locus-tag	class	description
AMC77_RS00005	COG0312	modulator of DNA gyrase
AMC77_RS00030	COG1104	cysteine desulfurase activity
AMC77_RS00035	COG0822	iron-sulfur transferase activity
AMC77_RS00040	COG0316	Belongs to the HesB IscA family
AMC77_RS00050	COG0443	Heat shock 70 kDa protein
AMC77_RS00060	COG0217	transcriptional regulatory protein
AMC77_RS00065	COG0799	negative regulation of ribosome biogenesis
AMC77_RS00075	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AMC77_RS00080	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AMC77_RS00105	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMC77_RS00125	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMC77_RS00130	COG0081	regulation of translation
AMC77_RS00135	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AMC77_RS00140	COG0222	ribosome binding
AMC77_RS00145	COG0085	RNA polymerase activity
AMC77_RS00150	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMC77_RS00155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AMC77_RS00160	COG0049	tRNA binding
AMC77_RS00165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMC77_RS00170	COG0051	transcription antitermination factor activity, RNA binding
AMC77_RS00175	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AMC77_RS00180	COG0088	Forms part of the polypeptide exit tunnel
AMC77_RS00185	COG0089	rRNA binding
AMC77_RS00190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AMC77_RS00195	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMC77_RS00200	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AMC77_RS00205	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMC77_RS00210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AMC77_RS00220	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMC77_RS00225	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AMC77_RS00230	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AMC77_RS00235	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AMC77_RS00240	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMC77_RS00245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AMC77_RS00250	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AMC77_RS00255	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AMC77_RS00260	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AMC77_RS00265	COG1841	ribosomal large subunit assembly
AMC77_RS00270	COG0200	Binds to the 23S rRNA
AMC77_RS00280	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMC77_RS00285	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMC77_RS00290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AMC77_RS00295	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AMC77_RS00300	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AMC77_RS00305	COG0202	RNA polymerase activity
AMC77_RS00310	COG0203	ribosomal protein L17
AMC77_RS00320	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMC77_RS00330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMC77_RS00335	COG0442	prolyl-tRNA aminoacylation
AMC77_RS00340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AMC77_RS00345	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AMC77_RS00350	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AMC77_RS00355	COG0439	Biotin carboxylase
AMC77_RS00360	COG0511	ligase activity, forming carbon-carbon bonds
AMC77_RS00365	COG0557	exoribonuclease II activity
AMC77_RS00375	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AMC77_RS00380	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMC77_RS00385	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AMC77_RS00390	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AMC77_RS00395	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AMC77_RS00405	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AMC77_RS00410	COG0039	L-malate dehydrogenase activity
AMC77_RS00425	COG1053	succinate dehydrogenase
AMC77_RS00430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AMC77_RS00435	COG0372	Belongs to the citrate synthase family
AMC77_RS00440	COG0567	Dehydrogenase, E1 component
AMC77_RS00445	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMC77_RS00450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMC77_RS00460	COG0105	UTP biosynthetic process
AMC77_RS00465	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMC77_RS00470	COG0124	histidyl-tRNA synthetase
AMC77_RS00475	COG1160	GTP binding
AMC77_RS00480	COG0740	serine-type endopeptidase activity
AMC77_RS00485	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMC77_RS00490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMC77_RS00495	COG1278	Cold shock
AMC77_RS00500	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AMC77_RS00505	COG0492	ferredoxin-NADP+ reductase activity
AMC77_RS00510	COG1674	ftsk spoiiie
AMC77_RS00525	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AMC77_RS00530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMC77_RS00535	COG0018	arginyl-trna synthetase
AMC77_RS00540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMC77_RS00545	COG0101	tRNA pseudouridine synthase activity
AMC77_RS00550	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AMC77_RS00555	COG0501	Belongs to the peptidase M48B family
AMC77_RS00575	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMC77_RS00580	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMC77_RS00585	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMC77_RS00590	COG0649	NAD binding
AMC77_RS00595	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AMC77_RS00600	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AMC77_RS00605	COG1034	ATP synthesis coupled electron transport
AMC77_RS00610	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMC77_RS00615	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMC77_RS00625	COG0713	ATP synthesis coupled electron transport
AMC77_RS00635	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMC77_RS00640	COG1007	ATP synthesis coupled electron transport
AMC77_RS00660	COG0483	inositol monophosphate 1-phosphatase activity
AMC77_RS00665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMC77_RS00670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMC77_RS00675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMC77_RS00675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMC77_RS00675	COG3321	synthase
AMC77_RS00675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMC77_RS00675	COG1028	Short-chain dehydrogenase reductase Sdr
AMC77_RS00680	COG4221	oxidoreductase activity
AMC77_RS00680	COG3321	synthase
AMC77_RS00680	COG1028	Short-chain dehydrogenase reductase Sdr
AMC77_RS00680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMC77_RS00685	COG2072	flavoprotein involved in K transport
AMC77_RS00695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AMC77_RS00695	COG2070	2-Nitropropane dioxygenase
AMC77_RS00715	COG1129	ABC transporter
AMC77_RS00720	COG1126	abc transporter atp-binding protein
AMC77_RS00725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMC77_RS00730	COG3425	synthase
AMC77_RS00740	COG1024	Enoyl-CoA hydratase
AMC77_RS00750	COG2070	2-Nitropropane dioxygenase
AMC77_RS00750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AMC77_RS00755	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AMC77_RS00760	COG0012	GTP binding
AMC77_RS00765	COG5007	Belongs to the BolA IbaG family
AMC77_RS00770	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMC77_RS00785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMC77_RS00785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMC77_RS00790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMC77_RS00800	COG0653	protein targeting
AMC77_RS00805	COG0482	sulfurtransferase activity
AMC77_RS00810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMC77_RS00825	COG0268	Binds directly to 16S ribosomal RNA
AMC77_RS00830	COG0728	peptidoglycan biosynthetic process
AMC77_RS00835	COG0275	rRNA processing
AMC77_RS00850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AMC77_RS00855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AMC77_RS00860	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AMC77_RS00870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMC77_RS00875	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AMC77_RS00880	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AMC77_RS00885	COG0181	hydroxymethylbilane synthase activity
AMC77_RS00890	COG1758	RNA polymerase activity
AMC77_RS00895	COG0194	GDP metabolic process
AMC77_RS00900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMC77_RS00905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMC77_RS00915	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMC77_RS00920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMC77_RS00930	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMC77_RS00945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMC77_RS00950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMC77_RS00960	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AMC77_RS00965	COG2890	protein-(glutamine-N5) methyltransferase activity
AMC77_RS00970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AMC77_RS00975	COG1253	flavin adenine dinucleotide binding
AMC77_RS00990	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AMC77_RS01005	COG1194	a g-specific adenine glycosylase
AMC77_RS01010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMC77_RS01015	COG3321	synthase
AMC77_RS01020	COG1028	Short-chain dehydrogenase reductase Sdr
AMC77_RS01020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMC77_RS01020	COG3321	synthase
AMC77_RS01020	COG4221	oxidoreductase activity
AMC77_RS01025	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMC77_RS01035	COG1214	PFAM Peptidase M22, glycoprotease
AMC77_RS01060	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AMC77_RS01065	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AMC77_RS01070	COG0195	Participates in both transcription termination and antitermination
AMC77_RS01070	COG2251	uridine kinase activity
AMC77_RS01085	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMC77_RS01090	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AMC77_RS01095	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMC77_RS01100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AMC77_RS01105	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMC77_RS01110	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMC77_RS01120	COG0356	it plays a direct role in the translocation of protons across the membrane
AMC77_RS01125	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMC77_RS01130	COG0154	amidase activity
AMC77_RS01135	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMC77_RS01140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AMC77_RS01155	COG0484	heat shock protein binding
AMC77_RS01160	COG0443	Heat shock 70 kDa protein
AMC77_RS01165	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMC77_RS01180	COG0495	leucyl-tRNA aminoacylation
AMC77_RS01185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMC77_RS01190	COG0321	lipoyl(octanoyl) transferase activity
AMC77_RS01195	COG0450	alkyl hydroperoxide reductase
AMC77_RS01200	COG0751	glycine-tRNA ligase activity
AMC77_RS01205	COG0752	glycyl-tRNA synthetase alpha subunit
AMC77_RS01210	COG4535	Mg2 and Co2 transporter CorC
AMC77_RS01215	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AMC77_RS01220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMC77_RS01225	COG0343	queuine tRNA-ribosyltransferase activity
AMC77_RS01230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMC77_RS01235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AMC77_RS01240	COG0525	valine-tRNA ligase activity
AMC77_RS01245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AMC77_RS01250	COG0563	adenylate kinase activity
AMC77_RS01255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMC77_RS01255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMC77_RS01270	COG0571	ribonuclease III activity
AMC77_RS01275	COG0481	GTPase activity
AMC77_RS01285	COG0242	peptide deformylase activity
AMC77_RS01305	COG0360	Binds together with S18 to 16S ribosomal RNA
AMC77_RS01310	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMC77_RS01315	COG0359	binds to the 23S rRNA
AMC77_RS01320	COG2925	Exonuclease
AMC77_RS01325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMC77_RS01325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMC77_RS01330	COG1678	Uncharacterized ACR, COG1678
AMC77_RS01335	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMC77_RS01340	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AMC77_RS01345	COG0542	response to heat
AMC77_RS01350	COG0415	Belongs to the DNA photolyase family
AMC77_RS01355	COG0629	single-stranded DNA binding
AMC77_RS01365	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AMC77_RS01385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMC77_RS01385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMC77_RS01390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMC77_RS01395	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMC77_RS01430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AMC77_RS01435	COG0564	pseudouridine synthase activity
AMC77_RS01440	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMC77_RS01445	COG2914	Belongs to the UPF0125 (RnfH) family
AMC77_RS01450	COG0281	malic enzyme
AMC77_RS01450	COG0280	phosphate acetyltransferase
AMC77_RS01455	COG0215	cysteine-tRNA ligase activity
AMC77_RS01460	COG0825	malonyl-CoA metabolic process
AMC77_RS01465	COG0037	tRNA processing
AMC77_RS01470	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AMC77_RS01480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMC77_RS01505	COG0616	signal peptide processing
AMC77_RS01505	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMC77_RS01510	COG0564	pseudouridine synthase activity
AMC77_RS01520	COG0717	Belongs to the dCTP deaminase family
AMC77_RS01525	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMC77_RS01530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AMC77_RS01535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMC77_RS01545	COG2878	Part of a membrane complex involved in electron transport
AMC77_RS01550	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AMC77_RS01555	COG0513	Belongs to the DEAD box helicase family
AMC77_RS01565	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AMC77_RS01570	COG0312	modulator of DNA gyrase
AMC77_RS01575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMC77_RS01585	COG1132	(ABC) transporter
AMC77_RS01590	COG0445	tRNA wobble uridine modification
AMC77_RS01595	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AMC77_RS01605	COG0706	membrane insertase activity
AMC77_RS01610	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AMC77_RS01615	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AMC77_RS01620	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AMC77_RS01625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AMC77_RS01630	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMC77_RS01640	COG0459	protein refolding
AMC77_RS01645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMC77_RS01650	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AMC77_RS01660	COG0592	DNA-directed DNA polymerase activity
AMC77_RS01670	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMC77_RS01680	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMC77_RS01685	COG0354	folic acid binding
AMC77_RS01690	COG0024	Methionine aminopeptidase
AMC77_RS01695	COG0052	Belongs to the universal ribosomal protein uS2 family
AMC77_RS01705	COG0528	UMP kinase activity
AMC77_RS01710	COG0233	cytoplasmic translational termination
AMC77_RS01715	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMC77_RS01720	COG0625	glutathione transferase activity
AMC77_RS01730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMC77_RS01735	COG0583	DNA-binding transcription factor activity
AMC77_RS01740	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMC77_RS01765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMC77_RS01765	COG1648	precorrin-2 dehydrogenase activity
AMC77_RS01775	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMC77_RS01780	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AMC77_RS01785	COG1185	polyribonucleotide nucleotidyltransferase activity
AMC77_RS01810	COG0492	ferredoxin-NADP+ reductase activity
AMC77_RS01815	COG0335	large ribosomal subunit rRNA binding
AMC77_RS01820	COG0336	Belongs to the RNA methyltransferase TrmD family
AMC77_RS01830	COG0228	four-way junction DNA binding
AMC77_RS01835	COG0861	Integral membrane protein TerC family
AMC77_RS01840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AMC77_RS01845	COG0045	succinate-CoA ligase (ADP-forming) activity
AMC77_RS01860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMC77_RS01870	COG0254	rRNA binding
AMC77_RS01875	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMC77_RS01895	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AMC77_RS01905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMC77_RS01910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMC77_RS01910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMC77_RS01915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMC77_RS01920	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMC77_RS01925	COG2945	thiolester hydrolase activity
AMC77_RS01935	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMC77_RS01940	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMC77_RS01945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AMC77_RS01960	COG0084	hydrolase, TatD family'
AMC77_RS01975	COG0148	phosphopyruvate hydratase activity