THSYN_RS30850 a8759c9639d31b6126ff1a63944789eb 1411 SUPERFAMILY SSF56112 529 790 1.8E-31 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS30850 a8759c9639d31b6126ff1a63944789eb 1411 Gene3D G3DSA:1.10.150.20 809 878 1.1E-5 T 29-03-2018 THSYN_RS30850 a8759c9639d31b6126ff1a63944789eb 1411 Pfam PF08378 Nuclease-related domain 15 132 4.8E-12 T 29-03-2018 IPR011528 Nuclease-related domain, NERD THSYN_RS30850 a8759c9639d31b6126ff1a63944789eb 1411 Pfam PF00069 Protein kinase domain 532 783 4.6E-17 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS30850 a8759c9639d31b6126ff1a63944789eb 1411 Pfam PF00069 Protein kinase domain 256 447 4.3E-11 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS30850 a8759c9639d31b6126ff1a63944789eb 1411 SMART SM00220 532 788 1.1E-11 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS30850 a8759c9639d31b6126ff1a63944789eb 1411 SUPERFAMILY SSF56112 207 504 4.76E-24 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS30850 a8759c9639d31b6126ff1a63944789eb 1411 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 538 565 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 THSYN_RS30850 a8759c9639d31b6126ff1a63944789eb 1411 Gene3D G3DSA:1.10.510.10 526 795 7.5E-31 T 29-03-2018 THSYN_RS30850 a8759c9639d31b6126ff1a63944789eb 1411 Gene3D G3DSA:1.10.510.10 208 509 4.1E-23 T 29-03-2018 THSYN_RS05995 4a8d9a45d464ab59e613ab8643bd5675 350 SUPERFAMILY SSF51569 7 348 2.93E-134 T 29-03-2018 THSYN_RS05995 4a8d9a45d464ab59e613ab8643bd5675 350 Gene3D G3DSA:3.20.20.70 8 350 4.9E-129 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS05995 4a8d9a45d464ab59e613ab8643bd5675 350 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 348 2.9E-159 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 THSYN_RS05995 4a8d9a45d464ab59e613ab8643bd5675 350 PIRSF PIRSF001361 1 350 5.8E-159 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 THSYN_RS05995 4a8d9a45d464ab59e613ab8643bd5675 350 Pfam PF00793 DAHP synthetase I family 44 337 3.1E-99 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THSYN_RS23680 efd273f6bcab8288e584de779d0ac585 126 Gene3D G3DSA:3.30.70.330 1 104 1.3E-29 T 29-03-2018 THSYN_RS23680 efd273f6bcab8288e584de779d0ac585 126 SUPERFAMILY SSF54928 2 110 1.14E-34 T 29-03-2018 IPR000504 RNA recognition motif domain GO:0003676 THSYN_RS23680 efd273f6bcab8288e584de779d0ac585 126 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 3 72 4.4E-22 T 29-03-2018 IPR000504 RNA recognition motif domain GO:0003676 THSYN_RS23680 efd273f6bcab8288e584de779d0ac585 126 SMART SM00360 2 75 6.8E-27 T 29-03-2018 IPR000504 RNA recognition motif domain GO:0003676 THSYN_RS14000 e6f821f9f1725b738a7e03c6371ebe8e 640 Gene3D G3DSA:2.160.20.10 261 498 4.6E-14 T 29-03-2018 IPR012334 Pectin lyase fold THSYN_RS14000 e6f821f9f1725b738a7e03c6371ebe8e 640 SUPERFAMILY SSF51126 154 496 2.46E-15 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS14000 e6f821f9f1725b738a7e03c6371ebe8e 640 SUPERFAMILY SSF103647 98 151 2.09E-10 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 THSYN_RS14000 e6f821f9f1725b738a7e03c6371ebe8e 640 Gene3D G3DSA:4.10.1080.10 81 260 2.3E-15 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 THSYN_RS14000 e6f821f9f1725b738a7e03c6371ebe8e 640 Gene3D G3DSA:4.10.1080.10 5 80 1.3E-12 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 THSYN_RS14000 e6f821f9f1725b738a7e03c6371ebe8e 640 SUPERFAMILY SSF103647 9 99 1.57E-15 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 THSYN_RS14000 e6f821f9f1725b738a7e03c6371ebe8e 640 Pfam PF02412 Thrombospondin type 3 repeat 104 138 3.8E-6 T 29-03-2018 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 THSYN_RS14000 e6f821f9f1725b738a7e03c6371ebe8e 640 Pfam PF02412 Thrombospondin type 3 repeat 69 101 0.014 T 29-03-2018 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 THSYN_RS14000 e6f821f9f1725b738a7e03c6371ebe8e 640 Pfam PF02412 Thrombospondin type 3 repeat 11 32 1.1E-4 T 29-03-2018 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 THSYN_RS14000 e6f821f9f1725b738a7e03c6371ebe8e 640 Pfam PF02412 Thrombospondin type 3 repeat 35 61 8.3E-5 T 29-03-2018 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 THSYN_RS29150 cb7bef5818456df896810af83d76ca42 141 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 133 2.2E-38 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29150 cb7bef5818456df896810af83d76ca42 141 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 86 3.0E-23 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29150 cb7bef5818456df896810af83d76ca42 141 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 84 1.3E-25 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29150 cb7bef5818456df896810af83d76ca42 141 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 133 6.2E-8 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29150 cb7bef5818456df896810af83d76ca42 141 SUPERFAMILY SSF46604 89 137 2.3E-12 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29150 cb7bef5818456df896810af83d76ca42 141 Gene3D G3DSA:2.60.15.10 1 90 1.3E-24 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29150 cb7bef5818456df896810af83d76ca42 141 SUPERFAMILY SSF51344 3 86 8.5E-21 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29150 cb7bef5818456df896810af83d76ca42 141 Gene3D G3DSA:1.20.5.440 91 136 2.7E-7 T 29-03-2018 THSYN_RS29150 cb7bef5818456df896810af83d76ca42 141 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 131 18.166 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS01110 cd4c529f98c801ac4485e71c43e6ef35 162 Pfam PF03737 Aldolase/RraA 5 153 1.0E-44 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein THSYN_RS01110 cd4c529f98c801ac4485e71c43e6ef35 162 SUPERFAMILY SSF89562 3 156 4.71E-48 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein THSYN_RS01110 cd4c529f98c801ac4485e71c43e6ef35 162 TIGRFAM TIGR01935 NOT-MenG: RraA family 5 154 3.0E-62 T 29-03-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 THSYN_RS01110 cd4c529f98c801ac4485e71c43e6ef35 162 Gene3D G3DSA:3.50.30.40 1 161 2.5E-47 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein THSYN_RS27670 9751b69a894a00535a5e6a1e69a08d68 804 Gene3D G3DSA:3.40.50.300 6 235 9.5E-57 T 29-03-2018 THSYN_RS27670 9751b69a894a00535a5e6a1e69a08d68 804 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 12 746 42.533 T 29-03-2018 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 THSYN_RS27670 9751b69a894a00535a5e6a1e69a08d68 804 SMART SM00490 270 351 2.0E-30 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS27670 9751b69a894a00535a5e6a1e69a08d68 804 SUPERFAMILY SSF52540 85 372 8.44E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27670 9751b69a894a00535a5e6a1e69a08d68 804 Gene3D G3DSA:3.40.50.300 236 386 4.8E-43 T 29-03-2018 THSYN_RS27670 9751b69a894a00535a5e6a1e69a08d68 804 Pfam PF00271 Helicase conserved C-terminal domain 245 351 4.1E-26 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS27670 9751b69a894a00535a5e6a1e69a08d68 804 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 165 173 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site THSYN_RS27670 9751b69a894a00535a5e6a1e69a08d68 804 SMART SM00487 36 234 2.9E-62 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS27670 9751b69a894a00535a5e6a1e69a08d68 804 Pfam PF03880 DbpA RNA binding domain 676 744 9.0E-22 T 29-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain THSYN_RS27670 9751b69a894a00535a5e6a1e69a08d68 804 Pfam PF00270 DEAD/DEAH box helicase 41 205 1.6E-44 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 207 29.437 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 Gene3D G3DSA:2.40.50.140 2 65 1.9E-23 T 29-03-2018 THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 Gene3D G3DSA:1.10.8.10 146 206 1.3E-10 T 29-03-2018 THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 SUPERFAMILY SSF50249 2 63 8.0E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 Gene3D G3DSA:1.10.150.20 114 142 0.0011 T 29-03-2018 THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 SUPERFAMILY SSF47781 66 133 2.45E-19 T 29-03-2018 IPR010994 RuvA domain 2-like THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 Pfam PF01330 RuvA N terminal domain 2 62 4.1E-19 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 Pfam PF07499 RuvA, C-terminal domain 163 205 6.6E-12 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 Gene3D G3DSA:1.10.150.20 66 113 2.9E-8 T 29-03-2018 THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 205 9.0E-50 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 SMART SM00278 108 127 0.069 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 SMART SM00278 73 92 120.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 SUPERFAMILY SSF46929 162 205 4.71E-8 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 THSYN_RS22320 9f03a38bcdcc8551eeaa4b4f7c6c020f 209 Pfam PF14520 Helix-hairpin-helix domain 72 130 4.1E-15 T 29-03-2018 THSYN_RS04630 c516bb618bbafa625ae97e9e7d9d2b31 585 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS04630 c516bb618bbafa625ae97e9e7d9d2b31 585 Gene3D G3DSA:3.40.50.300 338 569 7.6E-64 T 29-03-2018 THSYN_RS04630 c516bb618bbafa625ae97e9e7d9d2b31 585 Gene3D G3DSA:3.40.50.300 18 276 6.5E-54 T 29-03-2018 THSYN_RS04630 c516bb618bbafa625ae97e9e7d9d2b31 585 SUPERFAMILY SSF52540 24 242 2.04E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04630 c516bb618bbafa625ae97e9e7d9d2b31 585 SUPERFAMILY SSF52540 338 560 6.18E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04630 c516bb618bbafa625ae97e9e7d9d2b31 585 Pfam PF00005 ABC transporter 40 183 4.9E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS04630 c516bb618bbafa625ae97e9e7d9d2b31 585 Pfam PF00005 ABC transporter 358 501 3.1E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS04630 c516bb618bbafa625ae97e9e7d9d2b31 585 SMART SM00382 366 556 1.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS04630 c516bb618bbafa625ae97e9e7d9d2b31 585 SMART SM00382 49 273 3.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS09380 7777e4535fe8fe9d0084c56b1805f38e 229 SMART SM00382 38 225 1.8E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS09380 7777e4535fe8fe9d0084c56b1805f38e 229 Gene3D G3DSA:3.40.50.300 6 228 3.7E-61 T 29-03-2018 THSYN_RS09380 7777e4535fe8fe9d0084c56b1805f38e 229 Pfam PF00005 ABC transporter 29 175 1.6E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS09380 7777e4535fe8fe9d0084c56b1805f38e 229 SUPERFAMILY SSF52540 12 226 9.83E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09380 7777e4535fe8fe9d0084c56b1805f38e 229 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS19485 aca21acbf9e3ab3d94456f278e72d0e4 184 Gene3D G3DSA:2.60.40.680 2 160 1.7E-4 T 29-03-2018 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 7 587 7.5E-266 T 29-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 Gene3D G3DSA:1.20.58.100 430 539 5.5E-33 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 29-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 Gene3D G3DSA:4.10.80.40 540 587 2.2E-17 T 29-03-2018 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 SUPERFAMILY SSF56425 236 354 1.47E-42 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 Gene3D G3DSA:3.50.50.60 305 420 2.6E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 9 587 5.4E-238 T 29-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 SUPERFAMILY SSF51905 358 437 1.97E-76 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 SUPERFAMILY SSF51905 4 259 1.97E-76 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 Gene3D G3DSA:3.50.50.60 2 304 1.8E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 PIRSF PIRSF000171 1 580 1.2E-51 T 29-03-2018 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 Pfam PF00890 FAD binding domain 9 404 4.1E-116 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 Pfam PF02910 Fumarate reductase flavoprotein C-term 459 587 1.8E-40 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07590 3ab84c1b3798132a4b4b53436a1156be 587 SUPERFAMILY SSF46977 451 587 2.22E-51 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07985 7441251df54af1c2f53e677368981eb3 387 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 17 233 8.9E-71 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THSYN_RS07985 7441251df54af1c2f53e677368981eb3 387 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 7 251 18.234 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THSYN_RS07985 7441251df54af1c2f53e677368981eb3 387 ProSitePatterns PS01218 TatC family signature. 161 180 - T 29-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site THSYN_RS07985 7441251df54af1c2f53e677368981eb3 387 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 110 136 1.0E-46 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THSYN_RS07985 7441251df54af1c2f53e677368981eb3 387 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 15 42 1.0E-46 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THSYN_RS07985 7441251df54af1c2f53e677368981eb3 387 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 92 110 1.0E-46 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THSYN_RS07985 7441251df54af1c2f53e677368981eb3 387 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 161 189 1.0E-46 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THSYN_RS07985 7441251df54af1c2f53e677368981eb3 387 Pfam PF00902 Sec-independent protein translocase protein (TatC) 19 228 1.2E-63 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 SUPERFAMILY SSF47831 31 148 2.88E-27 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 456 471 1.0E-27 T 29-03-2018 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 473 488 1.0E-27 T 29-03-2018 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 300 319 1.0E-27 T 29-03-2018 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 509 521 1.0E-27 T 29-03-2018 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 259 547 4.4E-99 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 Gene3D G3DSA:3.20.20.60 262 579 1.1E-90 T 29-03-2018 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 Gene3D G3DSA:1.10.274.10 29 141 3.8E-28 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 SUPERFAMILY SSF52009 118 240 3.01E-28 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 Gene3D G3DSA:3.50.30.10 142 261 1.3E-25 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 Pfam PF05524 PEP-utilising enzyme, N-terminal 9 131 3.3E-27 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 456 474 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 Pfam PF00391 PEP-utilising enzyme, mobile domain 161 232 7.7E-20 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 8 555 1.4E-142 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 PIRSF PIRSF000732 3 578 3.1E-191 T 29-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 THSYN_RS02015 45dbed36a750dd4b81f57b73e905a6e1 580 SUPERFAMILY SSF51621 255 551 1.96E-95 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS29145 64cc36ade91d89c01a9ea0fc55bcec1f 947 ProSitePatterns PS00211 ABC transporters family signature. 833 847 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS29145 64cc36ade91d89c01a9ea0fc55bcec1f 947 SUPERFAMILY SSF52540 625 913 7.23E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29145 64cc36ade91d89c01a9ea0fc55bcec1f 947 Gene3D G3DSA:3.40.50.300 613 944 2.4E-53 T 29-03-2018 THSYN_RS29145 64cc36ade91d89c01a9ea0fc55bcec1f 947 Gene3D G3DSA:3.40.50.300 1 137 3.5E-15 T 29-03-2018 THSYN_RS29145 64cc36ade91d89c01a9ea0fc55bcec1f 947 Gene3D G3DSA:3.40.50.300 398 577 4.3E-15 T 29-03-2018 THSYN_RS29145 64cc36ade91d89c01a9ea0fc55bcec1f 947 Pfam PF00005 ABC transporter 807 863 6.7E-5 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS29145 64cc36ade91d89c01a9ea0fc55bcec1f 947 Gene3D G3DSA:1.10.8.280 291 397 1.2E-33 T 29-03-2018 THSYN_RS29145 64cc36ade91d89c01a9ea0fc55bcec1f 947 SUPERFAMILY SSF52540 2 202 5.83E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29145 64cc36ade91d89c01a9ea0fc55bcec1f 947 SUPERFAMILY SSF52540 434 573 5.83E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29145 64cc36ade91d89c01a9ea0fc55bcec1f 947 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 943 22.055 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 THSYN_RS29145 64cc36ade91d89c01a9ea0fc55bcec1f 947 Gene3D G3DSA:3.30.190.20 138 241 1.9E-40 T 29-03-2018 THSYN_RS29145 64cc36ade91d89c01a9ea0fc55bcec1f 947 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 2 928 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 THSYN_RS21955 1f73ec5419c1153a9e45a92a4e733657 275 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 215 2.2E-34 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS21955 1f73ec5419c1153a9e45a92a4e733657 275 SUPERFAMILY SSF53681 109 257 6.05E-37 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS21955 1f73ec5419c1153a9e45a92a4e733657 275 Hamap MF_00258 Glutamate racemase [murI]. 5 257 34.741 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS21955 1f73ec5419c1153a9e45a92a4e733657 275 SUPERFAMILY SSF53681 6 107 1.34E-31 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS21955 1f73ec5419c1153a9e45a92a4e733657 275 Gene3D G3DSA:3.40.50.1860 119 260 5.3E-41 T 29-03-2018 THSYN_RS21955 1f73ec5419c1153a9e45a92a4e733657 275 TIGRFAM TIGR00067 glut_race: glutamate racemase 7 244 2.3E-59 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS21955 1f73ec5419c1153a9e45a92a4e733657 275 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 180 190 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS21955 1f73ec5419c1153a9e45a92a4e733657 275 Gene3D G3DSA:3.40.50.1860 3 118 9.9E-28 T 29-03-2018 THSYN_RS01685 a835d44c6456f72340f93a1f5f5df636 340 PIRSF PIRSF006621 13 339 1.4E-96 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THSYN_RS01685 a835d44c6456f72340f93a1f5f5df636 340 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 14 331 9.5E-109 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 THSYN_RS01685 a835d44c6456f72340f93a1f5f5df636 340 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 105 123 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 THSYN_RS01685 a835d44c6456f72340f93a1f5f5df636 340 Pfam PF01207 Dihydrouridine synthase (Dus) 24 325 2.9E-91 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THSYN_RS01685 a835d44c6456f72340f93a1f5f5df636 340 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 12 333 45.038 T 29-03-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 THSYN_RS01685 a835d44c6456f72340f93a1f5f5df636 340 Gene3D G3DSA:3.20.20.70 19 252 2.5E-47 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS01685 a835d44c6456f72340f93a1f5f5df636 340 Gene3D G3DSA:1.10.1200.80 264 340 7.8E-23 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 THSYN_RS01685 a835d44c6456f72340f93a1f5f5df636 340 SUPERFAMILY SSF51395 21 331 8.61E-80 T 29-03-2018 THSYN_RS32600 9999cfd88a7c1162a674d8453ef5f4d1 316 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 16 309 7.6E-92 T 29-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 THSYN_RS32600 9999cfd88a7c1162a674d8453ef5f4d1 316 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 106 120 9.0E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THSYN_RS32600 9999cfd88a7c1162a674d8453ef5f4d1 316 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 9.0E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THSYN_RS32600 9999cfd88a7c1162a674d8453ef5f4d1 316 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 9.0E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THSYN_RS32600 9999cfd88a7c1162a674d8453ef5f4d1 316 Pfam PF00561 alpha/beta hydrolase fold 36 296 3.9E-28 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS32600 9999cfd88a7c1162a674d8453ef5f4d1 316 Gene3D G3DSA:3.40.50.1820 1 310 9.5E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS32600 9999cfd88a7c1162a674d8453ef5f4d1 316 SUPERFAMILY SSF53474 21 295 8.31E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS32600 9999cfd88a7c1162a674d8453ef5f4d1 316 PIRSF PIRSF006431 1 315 4.8E-107 T 29-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 THSYN_RS31045 2f989548ff645394ee3ae0e6b5aaaf86 217 PIRSF PIRSF003107 2 217 2.1E-55 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 THSYN_RS31045 2f989548ff645394ee3ae0e6b5aaaf86 217 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 213 4.9E-52 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 THSYN_RS31045 2f989548ff645394ee3ae0e6b5aaaf86 217 Gene3D G3DSA:1.20.58.220 104 213 1.0E-23 T 29-03-2018 THSYN_RS31045 2f989548ff645394ee3ae0e6b5aaaf86 217 Gene3D G3DSA:1.20.58.220 2 103 1.7E-16 T 29-03-2018 THSYN_RS31045 2f989548ff645394ee3ae0e6b5aaaf86 217 Pfam PF01895 PhoU domain 16 101 1.8E-15 T 29-03-2018 IPR026022 PhoU domain THSYN_RS31045 2f989548ff645394ee3ae0e6b5aaaf86 217 Pfam PF01895 PhoU domain 118 205 2.7E-17 T 29-03-2018 IPR026022 PhoU domain THSYN_RS31045 2f989548ff645394ee3ae0e6b5aaaf86 217 SUPERFAMILY SSF109755 5 216 2.62E-52 T 29-03-2018 THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 SMART SM00487 622 809 8.0E-33 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 SMART SM01058 501 598 1.1E-51 T 29-03-2018 IPR003711 CarD-like/TRCF domain THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 Gene3D G3DSA:3.40.50.300 813 978 1.5E-24 T 29-03-2018 THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 Gene3D G3DSA:3.40.50.300 321 799 1.0E-38 T 29-03-2018 THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 SUPERFAMILY SSF143517 1017 1168 7.32E-43 T 29-03-2018 THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 SMART SM00490 848 932 7.7E-16 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 166 1104 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 SUPERFAMILY SSF52540 24 354 1.01E-93 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 Pfam PF02559 CarD-like/TRCF domain 502 597 6.3E-26 T 29-03-2018 IPR003711 CarD-like/TRCF domain THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 Pfam PF00271 Helicase conserved C-terminal domain 828 931 9.5E-16 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 SMART SM00982 1030 1130 1.3E-50 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 SUPERFAMILY SSF141259 493 570 1.14E-24 T 29-03-2018 IPR003711 CarD-like/TRCF domain THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 SUPERFAMILY SSF52540 804 1012 7.37E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 SUPERFAMILY SSF52540 545 806 1.25E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 SUPERFAMILY SSF52540 373 488 1.06E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 41 1132 28.87 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 Pfam PF00270 DEAD/DEAH box helicase 627 787 1.0E-18 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS16625 4f96fe423fde6e6d652618a80745d18f 1169 Pfam PF03461 TRCF domain 1032 1123 1.3E-26 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 Pfam PF01436 NHL repeat 1244 1269 1.1E-5 T 29-03-2018 IPR001258 NHL repeat GO:0005515 THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 Pfam PF01436 NHL repeat 1300 1325 3.5E-4 T 29-03-2018 IPR001258 NHL repeat GO:0005515 THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 Pfam PF05593 RHS Repeat 2176 2212 1.5E-4 T 29-03-2018 IPR031325 RHS repeat THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 Pfam PF05593 RHS Repeat 1863 1897 5.5E-9 T 29-03-2018 IPR031325 RHS repeat THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 SUPERFAMILY SSF49299 360 434 9.55E-6 T 29-03-2018 IPR000601 PKD domain THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 SMART SM00736 435 531 0.0034 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 Gene3D G3DSA:2.120.10.30 1171 1240 3.4E-8 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 Gene3D G3DSA:2.120.10.30 1241 1401 1.2E-18 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 SMART SM00740 527 594 0.0042 T 29-03-2018 IPR005543 PASTA domain THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1562 1597 0.0015 T 29-03-2018 IPR006530 YD repeat THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1605 1643 1.1E-4 T 29-03-2018 IPR006530 YD repeat THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1583 1618 7.6E-4 T 29-03-2018 IPR006530 YD repeat THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2122 2151 0.0026 T 29-03-2018 IPR006530 YD repeat THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1540 1581 1.4E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1863 1894 3.4E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1842 1882 1.8E-7 T 29-03-2018 IPR006530 YD repeat THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 Gene3D G3DSA:2.120.10.30 1496 1629 1.6E-4 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 Gene3D G3DSA:3.40.1850.10 161 258 2.6E-24 T 29-03-2018 THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 Gene3D G3DSA:3.40.1850.10 259 352 5.1E-18 T 29-03-2018 THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 Gene3D G3DSA:3.40.1850.10 353 438 1.9E-14 T 29-03-2018 THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 SUPERFAMILY SSF49313 437 526 3.31E-13 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 SUPERFAMILY SSF101898 1469 1670 9.68E-12 T 29-03-2018 THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 SUPERFAMILY SSF101898 1187 1496 2.54E-36 T 29-03-2018 THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 Gene3D G3DSA:2.120.10.30 1402 1495 2.2E-11 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 2304 2381 5.8E-18 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 Gene3D G3DSA:2.60.40.1120 649 732 8.1E-6 T 29-03-2018 THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 Gene3D G3DSA:2.60.40.10 439 526 1.4E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 SUPERFAMILY SSF49299 153 245 1.31E-9 T 29-03-2018 IPR000601 PKD domain THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 SUPERFAMILY SSF49299 246 336 5.76E-6 T 29-03-2018 IPR000601 PKD domain THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 SMART SM00089 346 430 0.22 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 SMART SM00089 250 337 0.93 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 SMART SM00089 157 247 0.11 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS21670 d36c4b3ea52ffedbe9fbba5ed69e3b6c 2482 SUPERFAMILY SSF49464 650 718 8.24E-9 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain THSYN_RS17625 f18c803821a6467b7d9c008c776c0535 202 Gene3D G3DSA:3.40.50.2300 2 114 2.8E-27 T 29-03-2018 THSYN_RS17625 f18c803821a6467b7d9c008c776c0535 202 Gene3D G3DSA:1.10.10.10 115 198 2.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS17625 f18c803821a6467b7d9c008c776c0535 202 Pfam PF00072 Response regulator receiver domain 7 116 9.5E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS17625 f18c803821a6467b7d9c008c776c0535 202 SMART SM00448 5 116 3.8E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS17625 f18c803821a6467b7d9c008c776c0535 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 196 2.1E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS17625 f18c803821a6467b7d9c008c776c0535 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 7.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS17625 f18c803821a6467b7d9c008c776c0535 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 7.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS17625 f18c803821a6467b7d9c008c776c0535 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 7.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS17625 f18c803821a6467b7d9c008c776c0535 202 SUPERFAMILY SSF52172 4 156 5.12E-32 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS17625 f18c803821a6467b7d9c008c776c0535 202 SUPERFAMILY SSF46894 137 195 4.68E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS17625 f18c803821a6467b7d9c008c776c0535 202 SMART SM00421 140 197 7.6E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS31730 2fcdd1556e158d8452d5cedf0623f660 581 ProSitePatterns PS01130 SLC26A transporters signature. 53 74 - T 29-03-2018 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 Reactome: R-HSA-427601 THSYN_RS31730 2fcdd1556e158d8452d5cedf0623f660 581 Pfam PF00916 Sulfate permease family 24 387 2.2E-90 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 THSYN_RS31730 2fcdd1556e158d8452d5cedf0623f660 581 TIGRFAM TIGR00815 sulP: sulfate permease 11 546 4.1E-117 T 29-03-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 THSYN_RS31730 2fcdd1556e158d8452d5cedf0623f660 581 Pfam PF01740 STAS domain 445 537 1.3E-11 T 29-03-2018 IPR002645 STAS domain THSYN_RS31730 2fcdd1556e158d8452d5cedf0623f660 581 Gene3D G3DSA:3.30.750.24 420 559 1.6E-23 T 29-03-2018 IPR002645 STAS domain THSYN_RS31730 2fcdd1556e158d8452d5cedf0623f660 581 SUPERFAMILY SSF52091 446 553 3.34E-15 T 29-03-2018 IPR002645 STAS domain THSYN_RS23760 eff5732b1c2661ac8ecdb5b4b776c5ac 151 Pfam PF01724 Domain of unknown function DUF29 7 143 2.2E-48 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 TIGRFAM TIGR02917 PEP_TPR_lipo: putative PEP-CTERM system TPR-repeat lipoprotein 21 918 1.2E-123 T 29-03-2018 IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Pfam PF14559 Tetratricopeptide repeat 561 614 3.6E-6 T 29-03-2018 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Gene3D G3DSA:1.25.40.10 804 822 3.3E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Gene3D G3DSA:1.25.40.10 823 938 1.8E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Gene3D G3DSA:1.25.40.10 400 522 1.6E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Gene3D G3DSA:1.25.40.10 199 326 6.2E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Gene3D G3DSA:1.25.40.10 597 700 2.5E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Gene3D G3DSA:1.25.40.10 31 198 1.6E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Gene3D G3DSA:1.25.40.10 523 596 9.9E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SMART SM00028 244 277 59.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SMART SM00028 790 823 63.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SMART SM00028 617 650 120.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SMART SM00028 515 548 490.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SMART SM00028 857 890 260.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SMART SM00028 176 209 38.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SMART SM00028 142 175 20.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SMART SM00028 549 582 350.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SMART SM00028 210 243 5.1 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SMART SM00028 481 514 36.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SUPERFAMILY SSF48452 387 609 3.46E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SUPERFAMILY SSF48452 712 817 1.57E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Pfam PF13432 Tetratricopeptide repeat 282 336 6.9E-7 T 29-03-2018 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Pfam PF13432 Tetratricopeptide repeat 487 546 3.9E-5 T 29-03-2018 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Pfam PF13432 Tetratricopeptide repeat 217 276 0.013 T 29-03-2018 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Pfam PF13432 Tetratricopeptide repeat 149 210 3.2E-5 T 29-03-2018 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SUPERFAMILY SSF48452 146 367 3.8E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Gene3D G3DSA:1.25.40.10 703 803 2.4E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 SUPERFAMILY SSF48452 783 910 8.85E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Gene3D G3DSA:1.25.40.10 327 399 0.0015 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15905 297a9f5196cdd3cd8f4ff40e3dbb628a 939 Pfam PF13429 Tetratricopeptide repeat 795 913 4.7E-7 T 29-03-2018 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SUPERFAMILY SSF47384 1128 1210 6.08E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SMART SM00086 927 968 44.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SMART SM00086 469 512 5.2E-5 T 29-03-2018 IPR001610 PAC motif THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SUPERFAMILY SSF55874 1198 1369 6.68E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Gene3D G3DSA:3.30.450.20 844 972 1.3E-27 T 29-03-2018 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SUPERFAMILY SSF55781 510 687 2.84E-20 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Gene3D G3DSA:3.30.450.40 973 1140 5.3E-28 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Pfam PF08447 PAS fold 419 505 1.9E-19 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1145 1209 2.6E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SUPERFAMILY SSF55785 403 514 5.76E-19 T 29-03-2018 IPR000014 PAS domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Gene3D G3DSA:3.30.450.20 703 843 1.8E-25 T 29-03-2018 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SMART SM00091 706 772 2.6E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SMART SM00091 849 915 4.7E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SMART SM00091 395 463 6.4E-4 T 29-03-2018 IPR000014 PAS domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SUPERFAMILY SSF52172 1406 1526 3.42E-36 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SMART SM00388 1144 1209 3.7E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Pfam PF08448 PAS fold 715 820 8.6E-11 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Pfam PF04392 ABC transporter substrate binding protein 61 317 9.7E-6 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Gene3D G3DSA:3.30.565.10 1204 1373 9.0E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SMART SM00387 1258 1374 7.6E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Gene3D G3DSA:3.40.50.2300 162 254 4.8E-4 T 29-03-2018 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Gene3D G3DSA:3.30.450.20 368 525 1.4E-29 T 29-03-2018 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 851 975 3.8E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 703 826 1.6E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 394 518 5.7E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Gene3D G3DSA:1.10.287.130 1141 1203 6.2E-18 T 29-03-2018 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1258 1372 2.9E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Pfam PF13426 PAS domain 863 967 4.0E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Pfam PF01627 Hpt domain 1588 1674 7.4E-11 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SUPERFAMILY SSF47226 1566 1676 2.22E-19 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Pfam PF13185 GAF domain 541 686 3.0E-18 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Pfam PF13185 GAF domain 989 1122 1.6E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Gene3D G3DSA:3.40.50.2300 1396 1529 1.3E-36 T 29-03-2018 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SMART SM00448 1408 1521 1.2E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SUPERFAMILY SSF53271 83 204 5.38E-5 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SMART SM00065 541 695 0.0028 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SMART SM00065 990 1132 7.7E-12 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1334 1352 1.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1299 1313 1.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1358 1371 1.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1317 1327 1.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Gene3D G3DSA:1.20.120.160 1565 1677 1.7E-16 T 29-03-2018 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SUPERFAMILY SSF55785 700 817 2.74E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SUPERFAMILY SSF55785 864 977 7.41E-20 T 29-03-2018 IPR000014 PAS domain THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Pfam PF00072 Response regulator receiver domain 1410 1521 2.0E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 SUPERFAMILY SSF55781 973 1143 1.53E-20 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS05495 3caf7cd9a637f3adad5f7c3d5644c045 1684 Gene3D G3DSA:3.30.450.40 526 702 2.1E-27 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS04000 976938a122b27ed7bf4f19f0672544e0 131 Pfam PF07883 Cupin domain 32 99 2.5E-14 T 29-03-2018 IPR013096 Cupin 2, conserved barrel THSYN_RS04000 976938a122b27ed7bf4f19f0672544e0 131 Gene3D G3DSA:2.60.120.10 7 126 1.1E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS04000 976938a122b27ed7bf4f19f0672544e0 131 SUPERFAMILY SSF51182 17 113 2.88E-19 T 29-03-2018 IPR011051 RmlC-like cupin domain THSYN_RS18170 2b1bd4dead39089ae39cccb13b67eb03 541 SUPERFAMILY SSF56235 36 373 7.72E-38 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS18170 2b1bd4dead39089ae39cccb13b67eb03 541 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 36 289 5.3E-23 T 29-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal THSYN_RS18170 2b1bd4dead39089ae39cccb13b67eb03 541 Gene3D G3DSA:3.60.60.10 27 380 6.8E-47 T 29-03-2018 THSYN_RS12820 d8d7792329fa0a59d5adfe7db6f383e9 726 SUPERFAMILY SSF52540 5 643 1.48E-180 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12820 d8d7792329fa0a59d5adfe7db6f383e9 726 Pfam PF13361 UvrD-like helicase C-terminal domain 277 617 5.6E-67 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THSYN_RS12820 d8d7792329fa0a59d5adfe7db6f383e9 726 Gene3D G3DSA:3.40.50.300 283 385 6.3E-26 T 29-03-2018 THSYN_RS12820 d8d7792329fa0a59d5adfe7db6f383e9 726 Gene3D G3DSA:3.40.50.300 3 157 1.4E-27 T 29-03-2018 THSYN_RS12820 d8d7792329fa0a59d5adfe7db6f383e9 726 Gene3D G3DSA:3.40.50.300 158 282 7.1E-33 T 29-03-2018 THSYN_RS12820 d8d7792329fa0a59d5adfe7db6f383e9 726 Gene3D G3DSA:3.40.50.300 386 655 5.1E-53 T 29-03-2018 THSYN_RS12820 d8d7792329fa0a59d5adfe7db6f383e9 726 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 271 2.1E-74 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 THSYN_RS05800 c42e8b54b7edd223d346bd453767be02 287 Pfam PF00005 ABC transporter 56 211 2.9E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS05800 c42e8b54b7edd223d346bd453767be02 287 SMART SM00382 64 259 7.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS05800 c42e8b54b7edd223d346bd453767be02 287 ProSitePatterns PS00211 ABC transporters family signature. 184 198 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS05800 c42e8b54b7edd223d346bd453767be02 287 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 40 287 2.7E-120 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 THSYN_RS05800 c42e8b54b7edd223d346bd453767be02 287 SUPERFAMILY SSF52540 40 275 2.24E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05800 c42e8b54b7edd223d346bd453767be02 287 Gene3D G3DSA:3.40.50.300 31 285 1.0E-57 T 29-03-2018 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 467 58.295 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 466 1.3E-231 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 PRINTS PR00415 Aconitase family signature 83 96 2.6E-48 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 PRINTS PR00415 Aconitase family signature 134 149 2.6E-48 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 PRINTS PR00415 Aconitase family signature 196 209 2.6E-48 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 PRINTS PR00415 Aconitase family signature 210 223 2.6E-48 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 PRINTS PR00415 Aconitase family signature 344 355 2.6E-48 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 PRINTS PR00415 Aconitase family signature 109 117 2.6E-48 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 PRINTS PR00415 Aconitase family signature 287 301 2.6E-48 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 PRINTS PR00415 Aconitase family signature 120 133 2.6E-48 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 PRINTS PR00415 Aconitase family signature 401 414 2.6E-48 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 Gene3D G3DSA:3.30.499.10 317 467 8.8E-49 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 Pfam PF00330 Aconitase family (aconitate hydratase) 8 459 6.2E-151 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 Gene3D G3DSA:3.30.499.10 2 154 5.8E-39 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 SUPERFAMILY SSF53732 4 467 2.49E-159 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 ProSitePatterns PS01244 Aconitase family signature 2. 401 414 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 THSYN_RS10880 7cd0a9703804148664f419351f6685a1 467 Gene3D G3DSA:3.40.1060.10 155 289 5.3E-41 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS06290 63c5f69ef58da500e481540b22fae750 550 SUPERFAMILY SSF54862 451 550 5.83E-27 T 29-03-2018 THSYN_RS06290 63c5f69ef58da500e481540b22fae750 550 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 447 547 7.0E-48 T 29-03-2018 THSYN_RS06290 63c5f69ef58da500e481540b22fae750 550 Gene3D G3DSA:3.50.50.60 1 387 9.9E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS06290 63c5f69ef58da500e481540b22fae750 550 SUPERFAMILY SSF51905 308 449 4.62E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS06290 63c5f69ef58da500e481540b22fae750 550 SUPERFAMILY SSF51905 3 212 4.62E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS06290 63c5f69ef58da500e481540b22fae750 550 SUPERFAMILY SSF54373 212 307 5.89E-35 T 29-03-2018 THSYN_RS06290 63c5f69ef58da500e481540b22fae750 550 Pfam PF13450 NAD(P)-binding Rossmann-like domain 13 58 3.5E-8 T 29-03-2018 THSYN_RS06290 63c5f69ef58da500e481540b22fae750 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 1.5E-5 T 29-03-2018 THSYN_RS06290 63c5f69ef58da500e481540b22fae750 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 180 195 1.5E-5 T 29-03-2018 THSYN_RS28100 628d5589b00b431bab0c229d643701f9 228 SMART SM00479 43 217 2.7E-22 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THSYN_RS28100 628d5589b00b431bab0c229d643701f9 228 SUPERFAMILY SSF53098 34 213 7.97E-40 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS28100 628d5589b00b431bab0c229d643701f9 228 Pfam PF00929 Exonuclease 46 208 9.3E-19 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THSYN_RS28100 628d5589b00b431bab0c229d643701f9 228 Gene3D G3DSA:3.30.420.10 29 216 6.7E-31 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 287 403 2.6E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 SUPERFAMILY SSF52172 565 682 3.42E-32 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 Gene3D G3DSA:3.30.565.10 244 409 2.1E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 Gene3D G3DSA:3.40.50.2300 558 686 6.9E-34 T 29-03-2018 THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 Pfam PF00512 His Kinase A (phospho-acceptor) domain 175 239 7.6E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 SUPERFAMILY SSF47384 158 241 5.69E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 Gene3D G3DSA:3.40.50.2300 410 543 0.066 T 29-03-2018 THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 SMART SM00448 566 679 1.7E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 344 1.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 402 1.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 358 1.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 383 1.0E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 SMART SM00388 175 240 4.8E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 Pfam PF00072 Response regulator receiver domain 568 679 1.7E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 SUPERFAMILY SSF55874 230 403 6.29E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 SMART SM00387 287 405 3.0E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS17535 c339e65f9d5f7dadc069ae560a127e70 686 Gene3D G3DSA:1.10.287.130 165 236 3.5E-19 T 29-03-2018 THSYN_RS32050 ccfc22c38a9e679620300ec7c4bc7a4c 292 Gene3D G3DSA:3.40.50.720 111 238 1.4E-9 T 29-03-2018 THSYN_RS32050 ccfc22c38a9e679620300ec7c4bc7a4c 292 SUPERFAMILY SSF51735 103 220 7.34E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS32050 ccfc22c38a9e679620300ec7c4bc7a4c 292 SUPERFAMILY SSF53223 1 90 6.33E-34 T 29-03-2018 THSYN_RS32050 ccfc22c38a9e679620300ec7c4bc7a4c 292 Gene3D G3DSA:3.40.50.10280 1 110 1.8E-46 T 29-03-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal THSYN_RS32050 ccfc22c38a9e679620300ec7c4bc7a4c 292 Pfam PF09176 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal 10 90 5.4E-36 T 29-03-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal THSYN_RS16385 2c5c9a920fe66a13e198588e0003a4df 214 SUPERFAMILY SSF50475 16 214 4.68E-67 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 THSYN_RS16385 2c5c9a920fe66a13e198588e0003a4df 214 PIRSF PIRSF000190 3 214 2.4E-79 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THSYN_RS16385 2c5c9a920fe66a13e198588e0003a4df 214 Gene3D G3DSA:2.30.110.10 11 214 8.6E-76 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 THSYN_RS16385 2c5c9a920fe66a13e198588e0003a4df 214 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 12 214 1.2E-82 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THSYN_RS16385 2c5c9a920fe66a13e198588e0003a4df 214 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 173 214 9.6E-21 T 29-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THSYN_RS16385 2c5c9a920fe66a13e198588e0003a4df 214 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 11 214 39.32 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THSYN_RS16385 2c5c9a920fe66a13e198588e0003a4df 214 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 36 118 4.1E-24 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THSYN_RS16385 2c5c9a920fe66a13e198588e0003a4df 214 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 183 196 - T 29-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THSYN_RS29790 45e192cfa2ff03a50110be754a2df40c 310 Gene3D G3DSA:3.90.1530.10 1 88 5.0E-6 T 29-03-2018 THSYN_RS29790 45e192cfa2ff03a50110be754a2df40c 310 SUPERFAMILY SSF109709 117 194 1.27E-9 T 29-03-2018 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 525 918 6.3E-83 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 PIRSF PIRSF000853 5 925 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 Gene3D G3DSA:1.20.80.30 122 202 4.0E-27 T 29-03-2018 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 Gene3D G3DSA:3.20.20.60 540 923 2.4E-104 T 29-03-2018 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 6 920 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 Gene3D G3DSA:3.30.1490.20 6 121 2.3E-30 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 Gene3D G3DSA:1.10.189.10 349 396 1.9E-14 T 29-03-2018 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 Pfam PF00391 PEP-utilising enzyme, mobile domain 428 508 1.2E-25 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 SUPERFAMILY SSF56059 6 385 3.77E-122 T 29-03-2018 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 Gene3D G3DSA:3.50.30.10 397 539 7.6E-41 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 SUPERFAMILY SSF51621 696 919 1.01E-109 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 SUPERFAMILY SSF51621 516 651 1.01E-109 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 307 362 3.0E-7 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 21 298 4.4E-36 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 Gene3D G3DSA:3.30.470.20 250 347 1.4E-18 T 29-03-2018 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 455 466 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 THSYN_RS04560 e8027bfdf1a0d9b2cd3ea824a0ee009c 925 SUPERFAMILY SSF52009 396 517 4.19E-33 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THSYN_RS24200 60131ad090a355533fe105307780e19e 139 Pfam PF02657 Fe-S metabolism associated domain 10 133 4.1E-39 T 29-03-2018 IPR003808 Fe-S metabolism associated domain, SufE-like THSYN_RS24200 60131ad090a355533fe105307780e19e 139 SUPERFAMILY SSF82649 4 138 5.75E-36 T 29-03-2018 THSYN_RS24200 60131ad090a355533fe105307780e19e 139 Gene3D G3DSA:3.90.1010.10 1 138 1.3E-42 T 29-03-2018 THSYN_RS25470 202cfc48cec7b767e528b312f2e6fecb 775 Pfam PF13807 G-rich domain on putative tyrosine kinase 429 499 5.2E-12 T 29-03-2018 IPR032807 Tyrosine kinase, G-rich domain THSYN_RS25470 202cfc48cec7b767e528b312f2e6fecb 775 Pfam PF13614 AAA domain 581 695 2.7E-7 T 29-03-2018 IPR025669 AAA domain THSYN_RS25470 202cfc48cec7b767e528b312f2e6fecb 775 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 552 756 6.1E-51 T 29-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 THSYN_RS25470 202cfc48cec7b767e528b312f2e6fecb 775 Gene3D G3DSA:3.30.1890.10 80 477 4.7E-34 T 29-03-2018 THSYN_RS25470 202cfc48cec7b767e528b312f2e6fecb 775 Gene3D G3DSA:3.40.50.300 478 557 0.027 T 29-03-2018 THSYN_RS25470 202cfc48cec7b767e528b312f2e6fecb 775 Gene3D G3DSA:3.40.50.300 558 761 2.9E-34 T 29-03-2018 THSYN_RS25470 202cfc48cec7b767e528b312f2e6fecb 775 SUPERFAMILY SSF52540 571 759 8.28E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS25470 202cfc48cec7b767e528b312f2e6fecb 775 Pfam PF02706 Chain length determinant protein 48 138 2.7E-12 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 THSYN_RS01910 db52d878c89153ac9c47fee397bb1099 135 SUPERFAMILY SSF54631 8 127 8.59E-25 T 29-03-2018 THSYN_RS01910 db52d878c89153ac9c47fee397bb1099 135 Pfam PF00571 CBS domain 77 127 5.7E-12 T 29-03-2018 IPR000644 CBS domain THSYN_RS01910 db52d878c89153ac9c47fee397bb1099 135 SMART SM00116 84 131 3.3E-5 T 29-03-2018 IPR000644 CBS domain THSYN_RS01910 db52d878c89153ac9c47fee397bb1099 135 Gene3D G3DSA:3.10.580.10 3 128 2.4E-21 T 29-03-2018 THSYN_RS28560 98a85b0c5b7aa8e117f56263ffade282 112 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 23 104 1.1E-30 T 29-03-2018 IPR003849 Preprotein translocase YajC THSYN_RS28560 98a85b0c5b7aa8e117f56263ffade282 112 Pfam PF02699 Preprotein translocase subunit 26 101 3.0E-28 T 29-03-2018 IPR003849 Preprotein translocase YajC THSYN_RS28560 98a85b0c5b7aa8e117f56263ffade282 112 SMART SM01323 22 104 4.1E-41 T 29-03-2018 IPR003849 Preprotein translocase YajC THSYN_RS28560 98a85b0c5b7aa8e117f56263ffade282 112 PRINTS PR01853 Bacterial YajC preprotein translocase signature 24 44 1.8E-15 T 29-03-2018 IPR003849 Preprotein translocase YajC THSYN_RS28560 98a85b0c5b7aa8e117f56263ffade282 112 PRINTS PR01853 Bacterial YajC preprotein translocase signature 44 62 1.8E-15 T 29-03-2018 IPR003849 Preprotein translocase YajC THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 SUPERFAMILY SSF52440 1 127 9.5E-49 T 29-03-2018 IPR016185 Pre-ATP-grasp domain THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 Gene3D G3DSA:3.40.50.20 4 128 9.1E-38 T 29-03-2018 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 SUPERFAMILY SSF56059 128 401 1.54E-111 T 29-03-2018 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 Gene3D G3DSA:3.30.1490.20 655 744 3.4E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 SMART SM01096 424 547 3.1E-72 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 Gene3D G3DSA:3.40.50.1380 927 1054 1.3E-32 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1062 13.226 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1067 13.559 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 SUPERFAMILY SSF52440 556 675 1.05E-49 T 29-03-2018 IPR016185 Pre-ATP-grasp domain THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 709 723 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 547 9.1E-42 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 Gene3D G3DSA:1.10.1030.10 404 538 1.7E-53 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 SMART SM00851 955 1041 3.4E-31 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 Gene3D G3DSA:3.30.470.20 129 403 6.8E-69 T 29-03-2018 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.2E-65 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.2E-65 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.2E-65 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.2E-65 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.2E-65 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.2E-65 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 1.2E-65 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 Gene3D G3DSA:3.40.50.20 539 654 2.2E-63 T 29-03-2018 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1052 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 SUPERFAMILY SSF52335 935 1068 7.2E-36 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 SUPERFAMILY SSF48108 396 554 1.19E-51 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 Gene3D G3DSA:3.30.470.20 745 926 1.8E-38 T 29-03-2018 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 SUPERFAMILY SSF56059 673 932 1.5E-102 T 29-03-2018 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 Pfam PF02142 MGS-like domain 956 1041 5.0E-18 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 673 874 8.7E-33 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THSYN_RS22425 3a75a964ff55d1b16be132c3a2d8d06c 1068 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 3.2E-73 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THSYN_RS20515 283673992433cc4b9919239abe5c150a 269 SUPERFAMILY SSF54631 20 138 3.28E-30 T 29-03-2018 THSYN_RS20515 283673992433cc4b9919239abe5c150a 269 SMART SM00116 156 203 2.6E-6 T 29-03-2018 IPR000644 CBS domain THSYN_RS20515 283673992433cc4b9919239abe5c150a 269 SMART SM00116 27 74 1.5E-5 T 29-03-2018 IPR000644 CBS domain THSYN_RS20515 283673992433cc4b9919239abe5c150a 269 SMART SM00116 220 268 2.4E-8 T 29-03-2018 IPR000644 CBS domain THSYN_RS20515 283673992433cc4b9919239abe5c150a 269 SMART SM00116 91 139 1.7E-8 T 29-03-2018 IPR000644 CBS domain THSYN_RS20515 283673992433cc4b9919239abe5c150a 269 Pfam PF00571 CBS domain 216 268 4.4E-12 T 29-03-2018 IPR000644 CBS domain THSYN_RS20515 283673992433cc4b9919239abe5c150a 269 Pfam PF00571 CBS domain 21 72 8.8E-9 T 29-03-2018 IPR000644 CBS domain THSYN_RS20515 283673992433cc4b9919239abe5c150a 269 Pfam PF00571 CBS domain 149 201 8.4E-12 T 29-03-2018 IPR000644 CBS domain THSYN_RS20515 283673992433cc4b9919239abe5c150a 269 Pfam PF00571 CBS domain 84 138 1.3E-10 T 29-03-2018 IPR000644 CBS domain THSYN_RS20515 283673992433cc4b9919239abe5c150a 269 SUPERFAMILY SSF54631 146 268 5.68E-29 T 29-03-2018 THSYN_RS20515 283673992433cc4b9919239abe5c150a 269 Gene3D G3DSA:3.10.580.10 14 144 5.2E-32 T 29-03-2018 THSYN_RS20515 283673992433cc4b9919239abe5c150a 269 Gene3D G3DSA:3.10.580.10 145 269 2.0E-27 T 29-03-2018 THSYN_RS32375 26781d097b2cf506db01e57d147eb93e 279 Gene3D G3DSA:3.40.50.1220 3 277 8.2E-38 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS32375 26781d097b2cf506db01e57d147eb93e 279 SUPERFAMILY SSF52467 2 277 4.53E-66 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS32375 26781d097b2cf506db01e57d147eb93e 279 Pfam PF02146 Sir2 family 27 190 8.9E-20 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 THSYN_RS19240 260882e9fc145ac672eab1c2e8c0c11e 113 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 113 42.226 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 THSYN_RS19240 260882e9fc145ac672eab1c2e8c0c11e 113 TIGRFAM TIGR01165 cbiN: cobalt transport protein 4 90 2.0E-36 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 THSYN_RS19240 260882e9fc145ac672eab1c2e8c0c11e 113 Pfam PF02553 Cobalt transport protein component CbiN 5 75 7.5E-29 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 THSYN_RS19240 260882e9fc145ac672eab1c2e8c0c11e 113 Gene3D G3DSA:1.10.3720.10 1 99 0.0011 T 29-03-2018 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 SMART SM00387 777 890 2.6E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 Gene3D G3DSA:3.40.50.2300 904 1023 3.5E-30 T 29-03-2018 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 PRINTS PR01033 Phytochrome signature 480 498 7.4E-15 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 PRINTS PR01033 Phytochrome signature 260 281 7.4E-15 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 PRINTS PR01033 Phytochrome signature 173 192 7.4E-15 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 PRINTS PR01033 Phytochrome signature 447 466 7.4E-15 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 SUPERFAMILY SSF55785 17 134 3.63E-30 T 29-03-2018 IPR000014 PAS domain THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 Gene3D G3DSA:3.30.450.20 527 671 1.2E-20 T 29-03-2018 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 Gene3D G3DSA:1.10.287.130 672 725 3.3E-13 T 29-03-2018 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 SMART SM00448 907 1020 3.5E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 Gene3D G3DSA:3.30.450.20 14 133 1.1E-22 T 29-03-2018 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 SMART SM00388 666 731 5.4E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 Pfam PF01590 GAF domain 163 323 1.9E-15 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 SUPERFAMILY SSF47384 658 732 1.96E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 777 889 1.4E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 SUPERFAMILY SSF52172 906 1023 1.71E-31 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 SUPERFAMILY SSF55785 517 651 1.64E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 Gene3D G3DSA:3.30.565.10 726 890 7.0E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 SMART SM00065 158 328 1.3E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 Pfam PF08448 PAS fold 536 655 8.5E-8 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 SUPERFAMILY SSF55781 337 514 5.2E-38 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 Pfam PF00072 Response regulator receiver domain 909 1019 2.3E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 SUPERFAMILY SSF55781 161 322 1.32E-57 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 Pfam PF00512 His Kinase A (phospho-acceptor) domain 667 730 3.4E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 Pfam PF08446 PAS fold 27 135 2.8E-19 T 29-03-2018 IPR013654 PAS fold-2 GO:0006355 THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 Gene3D G3DSA:3.30.450.40 134 323 7.1E-39 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 SUPERFAMILY SSF55874 720 888 3.41E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS17620 c687ab65a52f4767f1dd742434612583 1024 Pfam PF00360 Phytochrome region 340 511 5.3E-41 T 29-03-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 THSYN_RS23380 2fdee1c6c98598decf4c0698c232b54f 168 SUPERFAMILY SSF56420 2 162 1.57E-47 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS23380 2fdee1c6c98598decf4c0698c232b54f 168 PRINTS PR01576 Peptide deformylase signature 94 105 2.3E-24 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS23380 2fdee1c6c98598decf4c0698c232b54f 168 PRINTS PR01576 Peptide deformylase signature 106 124 2.3E-24 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS23380 2fdee1c6c98598decf4c0698c232b54f 168 PRINTS PR01576 Peptide deformylase signature 125 154 2.3E-24 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS23380 2fdee1c6c98598decf4c0698c232b54f 168 PRINTS PR01576 Peptide deformylase signature 34 63 2.3E-24 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS23380 2fdee1c6c98598decf4c0698c232b54f 168 PIRSF PIRSF004749 1 165 5.1E-44 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS23380 2fdee1c6c98598decf4c0698c232b54f 168 Gene3D G3DSA:3.90.45.10 1 165 1.3E-46 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS23380 2fdee1c6c98598decf4c0698c232b54f 168 Hamap MF_00163 Peptide deformylase [def]. 2 166 25.013 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS23380 2fdee1c6c98598decf4c0698c232b54f 168 Pfam PF01327 Polypeptide deformylase 4 155 8.1E-40 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS23380 2fdee1c6c98598decf4c0698c232b54f 168 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 6 154 1.5E-37 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS02130 b06e32ee35d755bd7c8e3877c65fb0b4 229 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 161 182 - T 29-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 THSYN_RS02130 b06e32ee35d755bd7c8e3877c65fb0b4 229 Pfam PF01634 ATP phosphoribosyltransferase 70 219 1.4E-45 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 THSYN_RS02130 b06e32ee35d755bd7c8e3877c65fb0b4 229 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 21 202 5.1E-55 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 THSYN_RS02130 b06e32ee35d755bd7c8e3877c65fb0b4 229 Gene3D G3DSA:3.40.190.10 16 134 5.8E-36 T 29-03-2018 THSYN_RS02130 b06e32ee35d755bd7c8e3877c65fb0b4 229 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 20 226 52.629 T 29-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 THSYN_RS02130 b06e32ee35d755bd7c8e3877c65fb0b4 229 Gene3D G3DSA:3.40.190.10 135 194 1.4E-25 T 29-03-2018 THSYN_RS02130 b06e32ee35d755bd7c8e3877c65fb0b4 229 SUPERFAMILY SSF53850 19 225 8.9E-63 T 29-03-2018 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 SUPERFAMILY SSF51971 334 417 3.35E-46 T 29-03-2018 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 SUPERFAMILY SSF51971 146 301 3.35E-46 T 29-03-2018 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 Gene3D G3DSA:3.30.70.20 612 652 1.8E-9 T 29-03-2018 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 PRINTS PR00419 Adrenodoxin reductase family signature 281 295 1.3E-14 T 29-03-2018 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 PRINTS PR00419 Adrenodoxin reductase family signature 148 170 1.3E-14 T 29-03-2018 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 PRINTS PR00419 Adrenodoxin reductase family signature 171 184 1.3E-14 T 29-03-2018 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 PRINTS PR00419 Adrenodoxin reductase family signature 214 224 1.3E-14 T 29-03-2018 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 147 466 6.2E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 33 134 1.4E-11 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 Gene3D G3DSA:1.10.1060.10 15 141 8.2E-21 T 29-03-2018 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 633 644 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 SUPERFAMILY SSF54862 50 63 2.8E-17 T 29-03-2018 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 SUPERFAMILY SSF54862 563 650 2.8E-17 T 29-03-2018 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 Gene3D G3DSA:3.50.50.60 240 308 1.9E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 Pfam PF12838 4Fe-4S dicluster domain 597 646 1.7E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 Gene3D G3DSA:3.50.50.60 433 506 6.2E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 Gene3D G3DSA:3.30.70.20 526 611 0.0017 T 29-03-2018 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 Gene3D G3DSA:3.40.50.720 314 432 1.3E-10 T 29-03-2018 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 SUPERFAMILY SSF46548 46 157 5.75E-15 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS22660 3d3e86afcfc150f1f4027200d713fc05 654 Gene3D G3DSA:3.40.50.720 142 239 1.6E-16 T 29-03-2018 THSYN_RS08960 55ea5fcc00fb58afec34ee00511bc713 523 Gene3D G3DSA:3.40.50.1980 70 207 9.3E-46 T 29-03-2018 THSYN_RS08960 55ea5fcc00fb58afec34ee00511bc713 523 Gene3D G3DSA:3.40.50.1980 394 512 2.9E-29 T 29-03-2018 THSYN_RS08960 55ea5fcc00fb58afec34ee00511bc713 523 SUPERFAMILY SSF53807 3 522 2.06E-168 T 29-03-2018 THSYN_RS08960 55ea5fcc00fb58afec34ee00511bc713 523 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 70 501 3.1E-119 T 29-03-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 THSYN_RS08960 55ea5fcc00fb58afec34ee00511bc713 523 TIGRFAM TIGR01286 nifK: nitrogenase molybdenum-iron protein beta chain 2 523 1.6E-264 T 29-03-2018 IPR005976 Nitrogenase molybdenum-iron protein beta chain GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 THSYN_RS08960 55ea5fcc00fb58afec34ee00511bc713 523 Gene3D G3DSA:1.20.89.10 329 393 8.8E-27 T 29-03-2018 THSYN_RS08960 55ea5fcc00fb58afec34ee00511bc713 523 Pfam PF11844 Domain of unknown function (DUF3364) 1 56 2.7E-22 T 29-03-2018 IPR024564 Nitrogenase molybdenum-iron protein beta chain, N-terminal KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 THSYN_RS08960 55ea5fcc00fb58afec34ee00511bc713 523 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 151 165 - T 29-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 THSYN_RS08960 55ea5fcc00fb58afec34ee00511bc713 523 Gene3D G3DSA:3.40.50.1980 219 328 2.6E-29 T 29-03-2018 THSYN_RS08960 55ea5fcc00fb58afec34ee00511bc713 523 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 88 95 - T 29-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 THSYN_RS09820 ce71cf3988c9cd0af0242559acb9804d 1077 SMART SM00487 269 479 1.8E-5 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS09820 ce71cf3988c9cd0af0242559acb9804d 1077 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 6 213 8.3E-35 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THSYN_RS09820 ce71cf3988c9cd0af0242559acb9804d 1077 Pfam PF04851 Type III restriction enzyme, res subunit 294 437 1.7E-16 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS09820 ce71cf3988c9cd0af0242559acb9804d 1077 SUPERFAMILY SSF52540 240 474 5.9E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09820 ce71cf3988c9cd0af0242559acb9804d 1077 Gene3D G3DSA:3.40.50.300 216 457 8.8E-20 T 29-03-2018 THSYN_RS09820 ce71cf3988c9cd0af0242559acb9804d 1077 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 40 725 6.6E-144 T 29-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 THSYN_RS09820 ce71cf3988c9cd0af0242559acb9804d 1077 Pfam PF11867 Domain of unknown function (DUF3387) 733 1063 6.4E-27 T 29-03-2018 IPR021810 Protein of unknown function DUF3387 THSYN_RS17080 debeb5a7df5b0614f9e2c241be624c2f 369 Gene3D G3DSA:3.40.50.2000 1 167 7.1E-6 T 29-03-2018 THSYN_RS17080 debeb5a7df5b0614f9e2c241be624c2f 369 SUPERFAMILY SSF53756 2 358 1.38E-33 T 29-03-2018 THSYN_RS17080 debeb5a7df5b0614f9e2c241be624c2f 369 Gene3D G3DSA:3.40.50.2000 168 344 6.1E-14 T 29-03-2018 THSYN_RS24615 b362ebb8df5e428405b31229cdf7c110 427 SUPERFAMILY SSF142019 13 244 4.97E-83 T 29-03-2018 THSYN_RS24615 b362ebb8df5e428405b31229cdf7c110 427 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 54 223 1.8E-46 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24615 b362ebb8df5e428405b31229cdf7c110 427 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 346 357 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24615 b362ebb8df5e428405b31229cdf7c110 427 Pfam PF10531 SLBB domain 247 295 5.0E-15 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24615 b362ebb8df5e428405b31229cdf7c110 427 SUPERFAMILY SSF140490 330 422 1.31E-35 T 29-03-2018 THSYN_RS24615 b362ebb8df5e428405b31229cdf7c110 427 SMART SM00928 333 378 5.2E-26 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24615 b362ebb8df5e428405b31229cdf7c110 427 SUPERFAMILY SSF142984 245 327 1.03E-25 T 29-03-2018 THSYN_RS24615 b362ebb8df5e428405b31229cdf7c110 427 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 15 418 4.1E-189 T 29-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24615 b362ebb8df5e428405b31229cdf7c110 427 Gene3D G3DSA:3.10.560.10 239 317 5.3E-4 T 29-03-2018 THSYN_RS24615 b362ebb8df5e428405b31229cdf7c110 427 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 335 416 2.0E-29 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24615 b362ebb8df5e428405b31229cdf7c110 427 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 171 186 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS29160 634efb9836dae77e6ce5d361e3675647 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 287 7.8E-105 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29160 634efb9836dae77e6ce5d361e3675647 287 Gene3D G3DSA:3.40.1380.10 42 239 2.9E-68 T 29-03-2018 THSYN_RS29160 634efb9836dae77e6ce5d361e3675647 287 SUPERFAMILY SSF52943 2 287 5.49E-92 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29160 634efb9836dae77e6ce5d361e3675647 287 Gene3D G3DSA:1.10.287.80 2 41 2.1E-16 T 29-03-2018 THSYN_RS29160 634efb9836dae77e6ce5d361e3675647 287 Gene3D G3DSA:1.10.287.80 240 282 4.7E-15 T 29-03-2018 THSYN_RS29160 634efb9836dae77e6ce5d361e3675647 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 273 286 - T 29-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29160 634efb9836dae77e6ce5d361e3675647 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 287 35.282 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29160 634efb9836dae77e6ce5d361e3675647 287 Pfam PF00231 ATP synthase 5 286 1.8E-93 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29160 634efb9836dae77e6ce5d361e3675647 287 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 1.2E-34 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29160 634efb9836dae77e6ce5d361e3675647 287 PRINTS PR00126 ATP synthase gamma subunit signature 234 253 1.2E-34 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29160 634efb9836dae77e6ce5d361e3675647 287 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 1.2E-34 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29160 634efb9836dae77e6ce5d361e3675647 287 PRINTS PR00126 ATP synthase gamma subunit signature 265 286 1.2E-34 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 6.1E-18 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 SUPERFAMILY SSF68912 1 46 8.63E-13 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 8.6E-23 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 Gene3D G3DSA:1.10.720.10 1 43 6.3E-16 T 29-03-2018 THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 4.7E-213 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 SUPERFAMILY SSF50249 49 125 4.97E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 8.0E-31 T 29-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 Gene3D G3DSA:2.40.50.140 49 116 1.8E-30 T 29-03-2018 THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 SUPERFAMILY SSF52540 91 371 1.9E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 Gene3D G3DSA:3.40.50.300 129 418 1.5E-53 T 29-03-2018 THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 248.268 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 SMART SM00357 52 118 2.0E-16 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 SMART SM00382 170 355 4.3E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS13220 e5232e2d521bad666a3ac0a0f194fb46 418 SMART SM00959 5 47 1.1E-19 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 THSYN_RS18535 a20b3ce12d632c49095cfbc8dbc0f89c 582 Gene3D G3DSA:3.40.50.300 219 337 1.5E-11 T 29-03-2018 THSYN_RS18535 a20b3ce12d632c49095cfbc8dbc0f89c 582 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 256 321 4.2E-10 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS18535 a20b3ce12d632c49095cfbc8dbc0f89c 582 SUPERFAMILY SSF52540 247 331 2.79E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS18535 a20b3ce12d632c49095cfbc8dbc0f89c 582 SUPERFAMILY SSF52540 1 112 2.79E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS18535 a20b3ce12d632c49095cfbc8dbc0f89c 582 Pfam PF13175 AAA ATPase domain 1 42 5.7E-8 T 29-03-2018 THSYN_RS18535 a20b3ce12d632c49095cfbc8dbc0f89c 582 Gene3D G3DSA:3.40.50.300 1 110 6.9E-7 T 29-03-2018 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 SUPERFAMILY SSF55785 232 359 1.12E-25 T 29-03-2018 IPR000014 PAS domain THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 Gene3D G3DSA:3.30.450.20 78 236 1.6E-26 T 29-03-2018 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 Gene3D G3DSA:3.30.450.20 237 380 1.4E-33 T 29-03-2018 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 SUPERFAMILY SSF47384 367 448 5.49E-24 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 SUPERFAMILY SSF52172 630 758 1.12E-28 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 Gene3D G3DSA:3.30.565.10 442 604 1.3E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 SUPERFAMILY SSF55874 436 602 5.76E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 SMART SM00388 381 447 1.1E-25 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 113 241 2.7E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 242 368 1.9E-20 T 29-03-2018 IPR000014 PAS domain THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 SMART SM00448 629 751 1.2E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 SUPERFAMILY SSF55785 126 237 1.54E-20 T 29-03-2018 IPR000014 PAS domain THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 Gene3D G3DSA:3.40.50.2300 622 833 4.2E-30 T 29-03-2018 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 493 602 7.9E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 SMART SM00091 246 312 9.9E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 SMART SM00091 117 185 71.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 Gene3D G3DSA:1.10.287.130 381 441 5.1E-23 T 29-03-2018 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 SMART SM00387 493 604 1.6E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 Pfam PF08448 PAS fold 256 363 8.8E-14 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 Pfam PF08447 PAS fold 140 227 1.1E-15 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 PRINTS PR00344 Bacterial sensor protein C-terminal signature 548 558 2.8E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 544 2.8E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 PRINTS PR00344 Bacterial sensor protein C-terminal signature 564 582 2.8E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 PRINTS PR00344 Bacterial sensor protein C-terminal signature 588 601 2.8E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 SMART SM00086 318 361 4.6E-4 T 29-03-2018 IPR001610 PAC motif THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 SMART SM00086 192 234 8.4E-6 T 29-03-2018 IPR001610 PAC motif THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 Pfam PF00512 His Kinase A (phospho-acceptor) domain 381 447 3.8E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27160 f20caafdb44c3e28a985f4e80e146ed9 842 Pfam PF00072 Response regulator receiver domain 631 751 1.6E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS20915 f6680c3c51881c69222f620c81077b96 1040 SUPERFAMILY SSF52540 205 420 6.02E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS20915 f6680c3c51881c69222f620c81077b96 1040 Gene3D G3DSA:3.40.50.300 227 433 4.7E-20 T 29-03-2018 THSYN_RS20915 f6680c3c51881c69222f620c81077b96 1040 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 13 690 1.4E-149 T 29-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 THSYN_RS20915 f6680c3c51881c69222f620c81077b96 1040 SMART SM00487 245 451 1.1E-11 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS20915 f6680c3c51881c69222f620c81077b96 1040 Pfam PF04851 Type III restriction enzyme, res subunit 267 414 2.3E-14 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS20915 f6680c3c51881c69222f620c81077b96 1040 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 8 191 1.1E-31 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THSYN_RS17265 a643f923030e403b91c0d2b2e7f13947 324 SMART SM00382 40 233 5.3E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS17265 a643f923030e403b91c0d2b2e7f13947 324 SUPERFAMILY SSF52540 157 266 4.27E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17265 a643f923030e403b91c0d2b2e7f13947 324 SUPERFAMILY SSF52540 32 91 4.27E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17265 a643f923030e403b91c0d2b2e7f13947 324 Pfam PF07728 AAA domain (dynein-related subfamily) 44 224 2.7E-11 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THSYN_RS17265 a643f923030e403b91c0d2b2e7f13947 324 Gene3D G3DSA:3.40.50.300 25 271 9.3E-21 T 29-03-2018 THSYN_RS18835 918fccdcae31be62ed2d43fd4022a932 327 Gene3D G3DSA:3.40.50.300 41 210 1.5E-19 T 29-03-2018 THSYN_RS18835 918fccdcae31be62ed2d43fd4022a932 327 SMART SM00382 47 216 4.0E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS18835 918fccdcae31be62ed2d43fd4022a932 327 Pfam PF07728 AAA domain (dynein-related subfamily) 51 205 1.1E-15 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THSYN_RS18835 918fccdcae31be62ed2d43fd4022a932 327 SUPERFAMILY SSF52540 41 294 1.97E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS18835 918fccdcae31be62ed2d43fd4022a932 327 TIGRFAM TIGR02640 gas_vesic_GvpN: gas vesicle protein GvpN 28 288 1.2E-100 T 29-03-2018 IPR013462 Gas vesicle protein GvpN GO:0000166|GO:0005524|GO:0031411|GO:0031412 THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SMART SM01079 17 213 1.1E-74 T 29-03-2018 IPR006189 CHASE domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 Pfam PF13426 PAS domain 579 680 3.9E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SUPERFAMILY SSF55785 574 680 1.92E-27 T 29-03-2018 IPR000014 PAS domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 Pfam PF00563 EAL domain 872 1106 7.1E-68 T 29-03-2018 IPR001633 EAL domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 Gene3D G3DSA:3.20.20.450 858 1115 4.2E-88 T 29-03-2018 IPR001633 EAL domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 Pfam PF00990 Diguanylate cyclase, GGDEF domain 693 851 9.3E-46 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 Gene3D G3DSA:3.30.450.20 276 431 1.2E-16 T 29-03-2018 THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 Gene3D G3DSA:3.30.450.20 432 566 7.7E-23 T 29-03-2018 THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SUPERFAMILY SSF55785 294 430 1.7E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 689 855 1.7E-40 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 Gene3D G3DSA:3.40.50.10600 567 689 4.6E-26 T 29-03-2018 THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SMART SM00267 682 855 2.6E-60 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 Pfam PF03924 CHASE domain 21 211 7.4E-61 T 29-03-2018 IPR006189 CHASE domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SUPERFAMILY SSF141868 871 1123 5.23E-81 T 29-03-2018 IPR001633 EAL domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SMART SM00052 865 1111 7.4E-97 T 29-03-2018 IPR001633 EAL domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SMART SM00091 568 634 7.8E-4 T 29-03-2018 IPR000014 PAS domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SMART SM00091 444 511 46.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SMART SM00091 307 373 210.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SMART SM00086 393 432 60.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SMART SM00086 640 682 0.016 T 29-03-2018 IPR001610 PAC motif THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SMART SM00086 518 560 1.2 T 29-03-2018 IPR001610 PAC motif THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 Pfam PF08448 PAS fold 453 562 2.2E-7 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 Pfam PF08448 PAS fold 313 433 8.6E-8 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SUPERFAMILY SSF55073 698 856 1.1E-46 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 444 566 3.2E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 573 689 6.2E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 Gene3D G3DSA:3.30.70.270 690 857 1.6E-55 T 29-03-2018 THSYN_RS10110 c1f0e620cde8e60b752e7ddeb9127d2c 1251 SUPERFAMILY SSF55785 429 558 5.93E-19 T 29-03-2018 IPR000014 PAS domain THSYN_RS20670 e4b7ed65ed9217558a000d0694a166ff 360 Pfam PF07238 PilZ domain 249 354 3.7E-8 T 29-03-2018 IPR009875 PilZ domain GO:0035438 THSYN_RS20670 e4b7ed65ed9217558a000d0694a166ff 360 SUPERFAMILY SSF141371 245 354 2.63E-7 T 29-03-2018 THSYN_RS20670 e4b7ed65ed9217558a000d0694a166ff 360 SUPERFAMILY SSF55073 55 234 1.11E-57 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS20670 e4b7ed65ed9217558a000d0694a166ff 360 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 55 227 9.7E-36 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 THSYN_RS20670 e4b7ed65ed9217558a000d0694a166ff 360 SMART SM00044 19 217 6.2E-18 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 THSYN_RS20670 e4b7ed65ed9217558a000d0694a166ff 360 Gene3D G3DSA:3.30.70.1230 47 240 1.1E-51 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 THSYN_RS20670 e4b7ed65ed9217558a000d0694a166ff 360 Gene3D G3DSA:2.40.10.220 243 357 6.4E-11 T 29-03-2018 THSYN_RS22920 e295715136233b5ae473e24c028929e8 621 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 269 277 - T 29-03-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 THSYN_RS22920 e295715136233b5ae473e24c028929e8 621 Gene3D G3DSA:3.90.228.20 245 320 1.3E-21 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 THSYN_RS22920 e295715136233b5ae473e24c028929e8 621 Gene3D G3DSA:3.90.228.20 330 608 6.3E-114 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 THSYN_RS22920 e295715136233b5ae473e24c028929e8 621 Gene3D G3DSA:3.40.449.10 1 244 1.3E-114 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 THSYN_RS22920 e295715136233b5ae473e24c028929e8 621 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 245 604 3.0E-162 T 29-03-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 THSYN_RS22920 e295715136233b5ae473e24c028929e8 621 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 18 241 2.4E-103 T 29-03-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 THSYN_RS22920 e295715136233b5ae473e24c028929e8 621 SUPERFAMILY SSF53795 245 605 4.81E-148 T 29-03-2018 THSYN_RS22920 e295715136233b5ae473e24c028929e8 621 PIRSF PIRSF001348 1 608 1.2E-270 T 29-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 THSYN_RS22920 e295715136233b5ae473e24c028929e8 621 SUPERFAMILY SSF68923 6 244 1.1E-99 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 THSYN_RS22920 e295715136233b5ae473e24c028929e8 621 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 7 606 49.689 T 29-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SMART SM00086 1038 1080 1.8E-7 T 29-03-2018 IPR001610 PAC motif THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SUPERFAMILY SSF53335 289 481 3.12E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1087 1249 1.3E-46 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Pfam PF01739 CheR methyltransferase, SAM binding domain 289 475 4.1E-50 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SMART SM00091 845 911 1.8E-4 T 29-03-2018 IPR000014 PAS domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SMART SM00091 966 1032 7.8E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SMART SM00091 725 790 2.5 T 29-03-2018 IPR000014 PAS domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Pfam PF13426 PAS domain 977 1078 3.0E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1091 1247 4.3E-51 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SUPERFAMILY SSF55785 718 801 3.66E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Pfam PF13596 PAS domain 732 829 4.8E-6 T 29-03-2018 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SUPERFAMILY SSF55073 1096 1252 3.06E-51 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SMART SM00052 1261 1507 1.3E-106 T 29-03-2018 IPR001633 EAL domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SUPERFAMILY SSF55785 971 1078 5.93E-29 T 29-03-2018 IPR000014 PAS domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SUPERFAMILY SSF52738 22 208 1.03E-56 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Pfam PF03705 CheR methyltransferase, all-alpha domain 225 270 5.5E-11 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SUPERFAMILY SSF55785 829 949 1.34E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Gene3D G3DSA:3.40.50.180 15 213 6.9E-65 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SMART SM00267 1080 1251 7.1E-72 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Gene3D G3DSA:3.20.20.450 1254 1511 2.0E-91 T 29-03-2018 IPR001633 EAL domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 PRINTS PR00996 Glutamate methyltransferase family signature 281 293 6.8E-24 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 PRINTS PR00996 Glutamate methyltransferase family signature 244 257 6.8E-24 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 PRINTS PR00996 Glutamate methyltransferase family signature 422 436 6.8E-24 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 PRINTS PR00996 Glutamate methyltransferase family signature 320 340 6.8E-24 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 PRINTS PR00996 Glutamate methyltransferase family signature 356 372 6.8E-24 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 PRINTS PR00996 Glutamate methyltransferase family signature 441 464 6.8E-24 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Gene3D G3DSA:3.30.450.20 958 1077 3.7E-26 T 29-03-2018 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Gene3D G3DSA:1.20.5.400 648 721 1.7E-7 T 29-03-2018 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SUPERFAMILY SSF47757 221 290 8.37E-11 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Pfam PF00563 EAL domain 1270 1502 5.1E-66 T 29-03-2018 IPR001633 EAL domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Gene3D G3DSA:1.10.155.10 217 285 2.6E-11 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Gene3D G3DSA:3.30.450.20 722 839 4.1E-9 T 29-03-2018 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Gene3D G3DSA:3.30.450.20 840 957 8.0E-19 T 29-03-2018 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Gene3D G3DSA:3.30.70.270 1084 1253 2.3E-65 T 29-03-2018 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SMART SM00138 222 482 4.1E-75 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Gene3D G3DSA:3.40.50.150 287 482 3.9E-38 T 29-03-2018 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 SUPERFAMILY SSF141868 1267 1512 2.88E-82 T 29-03-2018 IPR001633 EAL domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Pfam PF08448 PAS fold 852 959 1.1E-13 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 846 965 6.8E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 970 1086 1.3E-19 T 29-03-2018 IPR000014 PAS domain THSYN_RS02175 104be9054ee4a2e22d62494baebb4f81 1520 Pfam PF01339 CheB methylesterase 28 202 1.3E-54 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Gene3D G3DSA:1.25.40.10 287 345 8.6E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Gene3D G3DSA:1.25.40.10 11 66 5.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Gene3D G3DSA:1.25.40.10 67 133 8.4E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Gene3D G3DSA:1.25.40.10 239 286 1.8E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Gene3D G3DSA:1.25.40.10 134 159 2.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SUPERFAMILY SSF52540 486 740 6.83E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Gene3D G3DSA:1.25.40.10 346 395 1.4E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Gene3D G3DSA:1.25.40.10 396 466 0.066 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Gene3D G3DSA:1.20.58.280 160 184 1.4E-8 T 29-03-2018 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SUPERFAMILY SSF48452 17 259 8.43E-34 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SUPERFAMILY SSF48452 224 406 1.18E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Gene3D G3DSA:1.25.40.10 185 238 1.2E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Pfam PF13432 Tetratricopeptide repeat 160 219 3.2E-10 T 29-03-2018 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Pfam PF13432 Tetratricopeptide repeat 27 86 7.5E-7 T 29-03-2018 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Pfam PF13432 Tetratricopeptide repeat 299 361 1.5E-10 T 29-03-2018 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Gene3D G3DSA:3.40.50.300 505 743 1.0E-38 T 29-03-2018 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SMART SM00028 52 85 24.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SMART SM00028 86 119 0.042 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SMART SM00028 260 293 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SMART SM00028 120 153 4.9 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SMART SM00028 226 259 0.022 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SMART SM00028 18 51 440.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SMART SM00028 154 187 0.0021 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SMART SM00028 294 327 340.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SMART SM00028 362 395 280.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SMART SM00028 188 221 3.3E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SMART SM00028 433 463 400.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 SMART SM00028 328 361 0.29 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16920 2264045f80966ee25156c6f783abfa7f 754 Pfam PF13469 Sulfotransferase family 508 705 8.1E-37 T 29-03-2018 THSYN_RS20365 e5c632f4537f29881753a203073df1b1 162 Gene3D G3DSA:3.30.1330.50 1 158 6.9E-72 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THSYN_RS20365 e5c632f4537f29881753a203073df1b1 162 Pfam PF02542 YgbB family 1 155 3.1E-65 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THSYN_RS20365 e5c632f4537f29881753a203073df1b1 162 SUPERFAMILY SSF69765 2 156 8.11E-65 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THSYN_RS20365 e5c632f4537f29881753a203073df1b1 162 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 155 7.1E-67 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THSYN_RS20365 e5c632f4537f29881753a203073df1b1 162 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 29-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THSYN_RS20365 e5c632f4537f29881753a203073df1b1 162 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 35.923 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THSYN_RS06485 a306a0ed6ac9afe27fb148530b6b3314 438 SUPERFAMILY SSF103473 22 426 3.92E-40 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS06485 a306a0ed6ac9afe27fb148530b6b3314 438 Gene3D G3DSA:1.20.1250.20 21 221 1.8E-16 T 29-03-2018 THSYN_RS06485 a306a0ed6ac9afe27fb148530b6b3314 438 Gene3D G3DSA:1.20.1250.20 229 432 1.5E-24 T 29-03-2018 THSYN_RS06485 a306a0ed6ac9afe27fb148530b6b3314 438 Pfam PF07690 Major Facilitator Superfamily 36 389 1.4E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THSYN_RS06485 a306a0ed6ac9afe27fb148530b6b3314 438 ProSitePatterns PS00216 Sugar transport proteins signature 1. 82 98 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THSYN_RS13365 5be79e96ab3bf1db871d8e15f9737f0d 140 Gene3D G3DSA:3.40.1440.10 29 134 3.2E-12 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily THSYN_RS13365 5be79e96ab3bf1db871d8e15f9737f0d 140 Pfam PF01541 GIY-YIG catalytic domain 37 131 2.6E-7 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily THSYN_RS13365 5be79e96ab3bf1db871d8e15f9737f0d 140 SUPERFAMILY SSF82771 37 132 1.1E-6 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily THSYN_RS13365 5be79e96ab3bf1db871d8e15f9737f0d 140 SMART SM00465 36 136 6.5E-6 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily THSYN_RS00225 3798709b29e515f7a34a7e39b568c876 338 Pfam PF00535 Glycosyl transferase family 2 16 181 5.2E-29 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS00225 3798709b29e515f7a34a7e39b568c876 338 Gene3D G3DSA:3.90.550.10 2 228 2.7E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS00225 3798709b29e515f7a34a7e39b568c876 338 SUPERFAMILY SSF53448 7 271 5.34E-41 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS17095 9422da843385d2879da736bdab37e8db 246 SUPERFAMILY SSF52833 6 240 9.13E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS17095 9422da843385d2879da736bdab37e8db 246 Gene3D G3DSA:3.40.30.10 4 156 1.5E-26 T 29-03-2018 THSYN_RS17095 9422da843385d2879da736bdab37e8db 246 Pfam PF08534 Redoxin 7 160 4.5E-30 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 THSYN_RS17095 9422da843385d2879da736bdab37e8db 246 TIGRFAM TIGR02190 GlrX-dom: glutaredoxin-family domain 164 242 5.9E-30 T 29-03-2018 IPR011906 Glutaredoxin domain KEGG: 00480+1.11.1.15 THSYN_RS17095 9422da843385d2879da736bdab37e8db 246 Pfam PF00462 Glutaredoxin 173 231 1.6E-15 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 THSYN_RS17095 9422da843385d2879da736bdab37e8db 246 Gene3D G3DSA:3.40.30.10 157 186 0.04 T 29-03-2018 THSYN_RS17095 9422da843385d2879da736bdab37e8db 246 ProSitePatterns PS00195 Glutaredoxin active site. 175 191 - T 29-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 THSYN_RS17095 9422da843385d2879da736bdab37e8db 246 PRINTS PR00160 Glutaredoxin signature 173 191 2.1E-9 T 29-03-2018 IPR014025 Glutaredoxin subgroup THSYN_RS17095 9422da843385d2879da736bdab37e8db 246 PRINTS PR00160 Glutaredoxin signature 214 227 2.1E-9 T 29-03-2018 IPR014025 Glutaredoxin subgroup THSYN_RS17095 9422da843385d2879da736bdab37e8db 246 PRINTS PR00160 Glutaredoxin signature 228 241 2.1E-9 T 29-03-2018 IPR014025 Glutaredoxin subgroup THSYN_RS17095 9422da843385d2879da736bdab37e8db 246 Gene3D G3DSA:3.40.30.10 187 242 9.9E-19 T 29-03-2018 THSYN_RS26470 b9e73af03847cae16dcc4b94eb342ea2 344 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 5 335 37.142 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 THSYN_RS26470 b9e73af03847cae16dcc4b94eb342ea2 344 SUPERFAMILY SSF52418 75 338 3.53E-92 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 THSYN_RS26470 b9e73af03847cae16dcc4b94eb342ea2 344 SUPERFAMILY SSF47648 1 67 2.75E-17 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 THSYN_RS26470 b9e73af03847cae16dcc4b94eb342ea2 344 Gene3D G3DSA:3.40.1030.10 74 344 1.5E-103 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 THSYN_RS26470 b9e73af03847cae16dcc4b94eb342ea2 344 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 64 1.4E-14 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 THSYN_RS26470 b9e73af03847cae16dcc4b94eb342ea2 344 Gene3D G3DSA:1.20.970.10 1 70 1.5E-19 T 29-03-2018 THSYN_RS26470 b9e73af03847cae16dcc4b94eb342ea2 344 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 8 334 3.5E-121 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 THSYN_RS26470 b9e73af03847cae16dcc4b94eb342ea2 344 Pfam PF00591 Glycosyl transferase family, a/b domain 78 325 1.0E-97 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 Gene3D G3DSA:3.30.565.10 260 426 1.2E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 SMART SM00387 302 418 1.5E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 Pfam PF00072 Response regulator receiver domain 36 147 7.2E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 SUPERFAMILY SSF55874 246 412 5.63E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 Gene3D G3DSA:1.10.287.130 191 251 3.1E-12 T 29-03-2018 THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 SUPERFAMILY SSF47384 176 257 1.41E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 302 414 4.2E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 SMART SM00388 191 256 2.2E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 SMART SM00448 34 147 1.4E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 Pfam PF00512 His Kinase A (phospho-acceptor) domain 191 255 2.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 396 8.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 357 8.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 371 8.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 Gene3D G3DSA:3.40.50.2300 25 190 3.8E-34 T 29-03-2018 THSYN_RS01440 5d5f450f397b36fa9ff0f56e6f644d39 431 SUPERFAMILY SSF52172 32 188 5.12E-34 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS16590 fb7f950bce8b6991ebd7f0a82e3f2bae 757 Gene3D G3DSA:3.40.718.10 447 722 1.5E-45 T 29-03-2018 THSYN_RS16590 fb7f950bce8b6991ebd7f0a82e3f2bae 757 Gene3D G3DSA:3.40.50.720 161 446 5.8E-78 T 29-03-2018 THSYN_RS16590 fb7f950bce8b6991ebd7f0a82e3f2bae 757 SUPERFAMILY SSF53223 9 161 3.09E-50 T 29-03-2018 THSYN_RS16590 fb7f950bce8b6991ebd7f0a82e3f2bae 757 Pfam PF01515 Phosphate acetyl/butaryl transferase 429 753 2.2E-78 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS16590 fb7f950bce8b6991ebd7f0a82e3f2bae 757 SMART SM00919 163 400 7.9E-130 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 THSYN_RS16590 fb7f950bce8b6991ebd7f0a82e3f2bae 757 SMART SM01274 18 151 1.3E-74 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 THSYN_RS16590 fb7f950bce8b6991ebd7f0a82e3f2bae 757 Pfam PF00390 Malic enzyme, N-terminal domain 19 150 2.4E-25 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 THSYN_RS16590 fb7f950bce8b6991ebd7f0a82e3f2bae 757 SUPERFAMILY SSF51735 163 441 8.45E-82 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS16590 fb7f950bce8b6991ebd7f0a82e3f2bae 757 Pfam PF03949 Malic enzyme, NAD binding domain 165 356 4.3E-16 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 THSYN_RS16590 fb7f950bce8b6991ebd7f0a82e3f2bae 757 SUPERFAMILY SSF53659 429 756 2.67E-79 T 29-03-2018 THSYN_RS16590 fb7f950bce8b6991ebd7f0a82e3f2bae 757 PIRSF PIRSF036684 1 757 0.0 T 29-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 THSYN_RS16590 fb7f950bce8b6991ebd7f0a82e3f2bae 757 Gene3D G3DSA:3.40.50.10380 5 160 2.8E-31 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 THSYN_RS24380 c7886213a24355b9471e1f3d1508ae47 354 Gene3D G3DSA:3.40.50.20 277 342 4.7E-6 T 29-03-2018 THSYN_RS24380 c7886213a24355b9471e1f3d1508ae47 354 Gene3D G3DSA:3.40.50.20 192 276 3.0E-17 T 29-03-2018 THSYN_RS24380 c7886213a24355b9471e1f3d1508ae47 354 SUPERFAMILY SSF51735 152 312 3.65E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS24380 c7886213a24355b9471e1f3d1508ae47 354 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 143 1.2E-26 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THSYN_RS24380 c7886213a24355b9471e1f3d1508ae47 354 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 178 206 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 THSYN_RS24380 c7886213a24355b9471e1f3d1508ae47 354 Gene3D G3DSA:3.90.180.10 6 191 2.1E-52 T 29-03-2018 THSYN_RS24380 c7886213a24355b9471e1f3d1508ae47 354 SUPERFAMILY SSF50129 9 173 5.93E-51 T 29-03-2018 IPR011032 GroES-like THSYN_RS24380 c7886213a24355b9471e1f3d1508ae47 354 SMART SM00829 11 342 4.9E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THSYN_RS24380 c7886213a24355b9471e1f3d1508ae47 354 Pfam PF00107 Zinc-binding dehydrogenase 185 308 5.6E-25 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THSYN_RS24380 c7886213a24355b9471e1f3d1508ae47 354 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 THSYN_RS07100 61ed0dc60c186d40c9d16cd9bb188b37 423 Gene3D G3DSA:3.40.50.410 227 365 3.9E-6 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS07100 61ed0dc60c186d40c9d16cd9bb188b37 423 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 423 38.664 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 THSYN_RS07100 61ed0dc60c186d40c9d16cd9bb188b37 423 Pfam PF04285 Protein of unknown function (DUF444) 3 421 9.3E-177 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 THSYN_RS07100 61ed0dc60c186d40c9d16cd9bb188b37 423 SUPERFAMILY SSF53300 251 351 1.11E-6 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS16695 6eaffee7a3566c2a0c9e73a88c6a6055 219 SUPERFAMILY SSF63380 94 194 7.99E-32 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THSYN_RS16695 6eaffee7a3566c2a0c9e73a88c6a6055 219 SUPERFAMILY SSF63380 1 88 2.3E-24 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THSYN_RS16695 6eaffee7a3566c2a0c9e73a88c6a6055 219 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 198 2.0E-62 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THSYN_RS16695 6eaffee7a3566c2a0c9e73a88c6a6055 219 Gene3D G3DSA:2.40.30.20 1 89 1.3E-26 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS16695 6eaffee7a3566c2a0c9e73a88c6a6055 219 Pfam PF00677 Lumazine binding domain 3 85 8.3E-21 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THSYN_RS16695 6eaffee7a3566c2a0c9e73a88c6a6055 219 Pfam PF00677 Lumazine binding domain 100 184 5.3E-24 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THSYN_RS16695 6eaffee7a3566c2a0c9e73a88c6a6055 219 Gene3D G3DSA:2.40.30.20 94 191 2.8E-34 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS16695 6eaffee7a3566c2a0c9e73a88c6a6055 219 PIRSF PIRSF000498 1 212 8.1E-71 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THSYN_RS18135 b18061110b0ae8a23b08aea912a6baed 657 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 494 646 2.4E-16 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 THSYN_RS18135 b18061110b0ae8a23b08aea912a6baed 657 Gene3D G3DSA:3.30.230.10 472 655 2.1E-25 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS18135 b18061110b0ae8a23b08aea912a6baed 657 TIGRFAM TIGR02688 TIGR02688: TIGR02688 family protein 1 439 5.6E-172 T 29-03-2018 IPR014061 Conserved hypothetical protein CHP02688 THSYN_RS18135 b18061110b0ae8a23b08aea912a6baed 657 SUPERFAMILY SSF54211 478 655 1.14E-25 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS18135 b18061110b0ae8a23b08aea912a6baed 657 Pfam PF13337 Putative ATP-dependent Lon protease 1 448 5.9E-171 T 29-03-2018 IPR014061 Conserved hypothetical protein CHP02688 THSYN_RS18135 b18061110b0ae8a23b08aea912a6baed 657 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 609 627 8.8E-6 T 29-03-2018 THSYN_RS18135 b18061110b0ae8a23b08aea912a6baed 657 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 586 605 8.8E-6 T 29-03-2018 THSYN_RS18135 b18061110b0ae8a23b08aea912a6baed 657 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 207 226 8.8E-6 T 29-03-2018 THSYN_RS18135 b18061110b0ae8a23b08aea912a6baed 657 TIGRFAM TIGR02653 Lon_rel_chp: conserved hypothetical protein 1 656 1.2E-291 T 29-03-2018 IPR013473 Conserved hypothetical protein CHP02653, peptidase S16 non-peptidase homologue THSYN_RS18135 b18061110b0ae8a23b08aea912a6baed 657 SUPERFAMILY SSF52540 201 417 4.13E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03115 cd2400f1e940c3c50fe3461769a5ea45 335 SMART SM00382 125 257 5.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS03115 cd2400f1e940c3c50fe3461769a5ea45 335 Gene3D G3DSA:3.40.50.300 86 271 6.2E-35 T 29-03-2018 THSYN_RS03115 cd2400f1e940c3c50fe3461769a5ea45 335 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 129 252 1.0E-26 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS03115 cd2400f1e940c3c50fe3461769a5ea45 335 SUPERFAMILY SSF52540 85 323 2.12E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24565 da4c92147e2728abcc2608079dbb1d1f 291 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 287 1.8E-108 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS24565 da4c92147e2728abcc2608079dbb1d1f 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 2.2E-32 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 THSYN_RS24565 da4c92147e2728abcc2608079dbb1d1f 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 2.2E-32 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 THSYN_RS24565 da4c92147e2728abcc2608079dbb1d1f 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 2.2E-32 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 THSYN_RS24565 da4c92147e2728abcc2608079dbb1d1f 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 2.2E-32 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 THSYN_RS24565 da4c92147e2728abcc2608079dbb1d1f 291 SUPERFAMILY SSF51569 1 290 3.66E-101 T 29-03-2018 THSYN_RS24565 da4c92147e2728abcc2608079dbb1d1f 291 PIRSF PIRSF001365 1 291 2.7E-89 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 THSYN_RS24565 da4c92147e2728abcc2608079dbb1d1f 291 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 THSYN_RS24565 da4c92147e2728abcc2608079dbb1d1f 291 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 287 65.996 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS24565 da4c92147e2728abcc2608079dbb1d1f 291 Gene3D G3DSA:3.20.20.70 1 291 2.4E-97 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS24565 da4c92147e2728abcc2608079dbb1d1f 291 SMART SM01130 1 289 4.6E-142 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 THSYN_RS24565 da4c92147e2728abcc2608079dbb1d1f 291 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS24565 da4c92147e2728abcc2608079dbb1d1f 291 Pfam PF00701 Dihydrodipicolinate synthetase family 2 287 6.3E-102 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 THSYN_RS02430 23c465cc424cb9fb8fb5272aa8588bd9 389 SUPERFAMILY SSF53756 1 381 1.78E-51 T 29-03-2018 THSYN_RS02430 23c465cc424cb9fb8fb5272aa8588bd9 389 Pfam PF13439 Glycosyltransferase Family 4 16 178 1.1E-15 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS02430 23c465cc424cb9fb8fb5272aa8588bd9 389 Gene3D G3DSA:3.40.50.2000 9 192 5.0E-6 T 29-03-2018 THSYN_RS02430 23c465cc424cb9fb8fb5272aa8588bd9 389 Gene3D G3DSA:3.40.50.2000 193 364 5.0E-27 T 29-03-2018 THSYN_RS02430 23c465cc424cb9fb8fb5272aa8588bd9 389 Pfam PF13692 Glycosyl transferases group 1 199 311 7.5E-18 T 29-03-2018 THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SUPERFAMILY SSF55073 976 1134 3.14E-49 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SUPERFAMILY SSF55785 428 555 9.83E-30 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Gene3D G3DSA:3.20.20.450 1133 1390 3.3E-88 T 29-03-2018 IPR001633 EAL domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SMART SM00086 263 303 7.4 T 29-03-2018 IPR001610 PAC motif THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SMART SM00086 918 960 3.3E-5 T 29-03-2018 IPR001610 PAC motif THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SMART SM00086 515 557 6.0E-8 T 29-03-2018 IPR001610 PAC motif THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SMART SM00086 389 431 3.7E-6 T 29-03-2018 IPR001610 PAC motif THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SMART SM00086 796 838 3.7E-6 T 29-03-2018 IPR001610 PAC motif THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 967 1132 5.6E-43 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Gene3D G3DSA:3.30.450.40 568 708 3.3E-12 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SMART SM00065 575 720 0.0025 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Gene3D G3DSA:3.30.70.270 965 1132 8.4E-58 T 29-03-2018 THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SUPERFAMILY SSF141868 1149 1396 2.22E-79 T 29-03-2018 IPR001633 EAL domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SUPERFAMILY SSF55785 854 957 3.06E-28 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Pfam PF08448 PAS fold 212 305 1.2E-7 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SMART SM00091 724 790 2.2E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SMART SM00091 315 383 2.5 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SMART SM00091 846 912 2.0E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SMART SM00091 192 262 2.4E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SMART SM00091 443 509 1.1E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SMART SM00267 960 1133 7.6E-64 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Gene3D G3DSA:3.30.450.20 849 964 1.2E-25 T 29-03-2018 THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Pfam PF00563 EAL domain 1149 1383 3.4E-67 T 29-03-2018 IPR001633 EAL domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Gene3D G3DSA:3.30.450.20 177 309 8.1E-25 T 29-03-2018 THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Gene3D G3DSA:3.30.450.20 436 567 8.8E-38 T 29-03-2018 THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Gene3D G3DSA:3.30.450.20 310 435 3.2E-28 T 29-03-2018 THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Gene3D G3DSA:3.30.450.20 709 848 3.8E-36 T 29-03-2018 THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SMART SM00052 1143 1388 5.1E-96 T 29-03-2018 IPR001633 EAL domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 851 967 3.1E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 721 845 1.3E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 189 309 1.9E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 439 560 2.0E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 363 438 7.3E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SUPERFAMILY SSF55781 577 722 1.15E-14 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SUPERFAMILY SSF55785 300 429 1.01E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Pfam PF13426 PAS domain 857 958 6.4E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SUPERFAMILY SSF55785 178 301 4.05E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Pfam PF08447 PAS fold 338 424 7.2E-16 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Pfam PF08447 PAS fold 747 831 2.4E-17 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Pfam PF08447 PAS fold 466 550 1.3E-18 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 Pfam PF00990 Diguanylate cyclase, GGDEF domain 971 1128 3.7E-50 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS13810 f692dfacf4d2ea67221688e708c53395 1422 SUPERFAMILY SSF55785 711 835 2.26E-26 T 29-03-2018 IPR000014 PAS domain THSYN_RS03365 e5fc2a6fb39f84516356c9509867d09c 140 Pfam PF00472 RF-1 domain 7 133 1.9E-22 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THSYN_RS03365 e5fc2a6fb39f84516356c9509867d09c 140 SUPERFAMILY SSF110916 7 100 6.02E-15 T 29-03-2018 THSYN_RS03365 e5fc2a6fb39f84516356c9509867d09c 140 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THSYN_RS03365 e5fc2a6fb39f84516356c9509867d09c 140 Gene3D G3DSA:3.30.160.20 1 140 6.9E-43 T 29-03-2018 THSYN_RS03050 6b320c2d3756c7bee239e256a84debf9 238 SMART SM00382 36 233 4.7E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS03050 6b320c2d3756c7bee239e256a84debf9 238 Pfam PF00005 ABC transporter 27 178 2.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS03050 6b320c2d3756c7bee239e256a84debf9 238 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS03050 6b320c2d3756c7bee239e256a84debf9 238 SUPERFAMILY SSF52540 8 231 1.3E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03050 6b320c2d3756c7bee239e256a84debf9 238 Gene3D G3DSA:3.40.50.300 4 234 1.3E-57 T 29-03-2018 THSYN_RS20475 2b60cb1433e898c619b09f5a74bb7aca 242 Gene3D G3DSA:3.30.420.10 2 177 1.3E-38 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS20475 2b60cb1433e898c619b09f5a74bb7aca 242 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 235 1.6E-89 T 29-03-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS20475 2b60cb1433e898c619b09f5a74bb7aca 242 SMART SM00479 2 175 3.0E-46 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THSYN_RS20475 2b60cb1433e898c619b09f5a74bb7aca 242 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 196 5.8E-65 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS20475 2b60cb1433e898c619b09f5a74bb7aca 242 Pfam PF00929 Exonuclease 4 166 3.2E-37 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THSYN_RS20475 2b60cb1433e898c619b09f5a74bb7aca 242 SUPERFAMILY SSF53098 1 173 5.06E-53 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS28325 0217ae672cfd64b03a6431939f87a113 145 ProDom PD005668 HYDROGENASE HUPH HYDROGENASE-1 EXPRESSION/FORMATION OPERON PROTEIN C-TERMINAL EXPRESSION HYAF HOXQ 21 117 6.0E-17 T 29-03-2018 IPR006894 HupH hydrogenase expression protein, C-terminal THSYN_RS28325 0217ae672cfd64b03a6431939f87a113 145 Pfam PF04809 HupH hydrogenase expression protein, C-terminal conserved region 21 133 1.1E-27 T 29-03-2018 IPR006894 HupH hydrogenase expression protein, C-terminal THSYN_RS07340 469bc800d49f6cc1cf709d2ee083d20d 180 Pfam PF00072 Response regulator receiver domain 9 117 1.3E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS07340 469bc800d49f6cc1cf709d2ee083d20d 180 SMART SM00448 6 117 2.2E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS07340 469bc800d49f6cc1cf709d2ee083d20d 180 Pfam PF02954 Bacterial regulatory protein, Fis family 137 174 8.0E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS07340 469bc800d49f6cc1cf709d2ee083d20d 180 SUPERFAMILY SSF52172 8 164 1.2E-28 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS07340 469bc800d49f6cc1cf709d2ee083d20d 180 Gene3D G3DSA:3.40.50.2300 2 120 1.3E-24 T 29-03-2018 THSYN_RS07340 469bc800d49f6cc1cf709d2ee083d20d 180 Gene3D G3DSA:1.10.10.60 129 174 4.1E-14 T 29-03-2018 THSYN_RS32910 869f3e3119e5146064cd2fd383128c65 93 Pfam PF09827 CRISPR associated protein Cas2 3 71 1.0E-18 T 29-03-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 THSYN_RS32910 869f3e3119e5146064cd2fd383128c65 93 Gene3D G3DSA:3.30.70.240 1 93 4.4E-23 T 29-03-2018 THSYN_RS32910 869f3e3119e5146064cd2fd383128c65 93 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 2 90 14.592 T 29-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THSYN_RS32910 869f3e3119e5146064cd2fd383128c65 93 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 4 84 9.0E-17 T 29-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THSYN_RS32910 869f3e3119e5146064cd2fd383128c65 93 SUPERFAMILY SSF143430 2 75 5.89E-18 T 29-03-2018 THSYN_RS14250 7ce6acea1bd714b530a15456926f4811 296 ProSitePatterns PS00567 Phosphoribulokinase signature. 164 177 - T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS14250 7ce6acea1bd714b530a15456926f4811 296 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 214 3.0E-61 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 THSYN_RS14250 7ce6acea1bd714b530a15456926f4811 296 PRINTS PR00478 Phosphoribulokinase family signature 164 181 7.0E-29 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS14250 7ce6acea1bd714b530a15456926f4811 296 PRINTS PR00478 Phosphoribulokinase family signature 126 144 7.0E-29 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS14250 7ce6acea1bd714b530a15456926f4811 296 PRINTS PR00478 Phosphoribulokinase family signature 12 29 7.0E-29 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS14250 7ce6acea1bd714b530a15456926f4811 296 PRINTS PR00478 Phosphoribulokinase family signature 182 205 7.0E-29 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS14250 7ce6acea1bd714b530a15456926f4811 296 Gene3D G3DSA:3.40.50.300 1 291 1.6E-35 T 29-03-2018 THSYN_RS14250 7ce6acea1bd714b530a15456926f4811 296 SUPERFAMILY SSF52540 4 287 3.2E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29435 e20a60f2b145cf0796c0cd26d5c15249 206 SUPERFAMILY SSF46955 4 47 1.33E-10 T 29-03-2018 IPR009061 Putative DNA-binding domain THSYN_RS29435 e20a60f2b145cf0796c0cd26d5c15249 206 SMART SM00857 60 194 1.4E-21 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THSYN_RS29435 e20a60f2b145cf0796c0cd26d5c15249 206 Pfam PF00239 Resolvase, N terminal domain 61 189 3.6E-20 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THSYN_RS29435 e20a60f2b145cf0796c0cd26d5c15249 206 ProSitePatterns PS00397 Site-specific recombinases active site. 63 71 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 THSYN_RS29435 e20a60f2b145cf0796c0cd26d5c15249 206 SUPERFAMILY SSF53041 58 190 6.93E-24 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THSYN_RS29435 e20a60f2b145cf0796c0cd26d5c15249 206 Gene3D G3DSA:3.40.50.1390 55 203 4.7E-30 T 29-03-2018 THSYN_RS29435 e20a60f2b145cf0796c0cd26d5c15249 206 Pfam PF00376 MerR family regulatory protein 5 41 6.9E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THSYN_RS29435 e20a60f2b145cf0796c0cd26d5c15249 206 SMART SM00422 4 85 0.0054 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THSYN_RS29435 e20a60f2b145cf0796c0cd26d5c15249 206 Gene3D G3DSA:1.10.1660.10 2 47 1.1E-13 T 29-03-2018 THSYN_RS24840 52155552c0e03267af29d30b9dc7621f 1164 Pfam PF00271 Helicase conserved C-terminal domain 719 839 5.9E-15 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS24840 52155552c0e03267af29d30b9dc7621f 1164 SUPERFAMILY SSF52540 719 863 4.36E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24840 52155552c0e03267af29d30b9dc7621f 1164 SUPERFAMILY SSF52540 305 403 4.36E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24840 52155552c0e03267af29d30b9dc7621f 1164 SMART SM00487 251 419 2.3E-11 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS24840 52155552c0e03267af29d30b9dc7621f 1164 Gene3D G3DSA:3.40.50.300 708 1022 3.3E-24 T 29-03-2018 THSYN_RS24840 52155552c0e03267af29d30b9dc7621f 1164 SUPERFAMILY SSF56024 121 198 5.49E-7 T 29-03-2018 THSYN_RS24840 52155552c0e03267af29d30b9dc7621f 1164 Gene3D G3DSA:3.40.50.10810 228 436 3.5E-18 T 29-03-2018 THSYN_RS24840 52155552c0e03267af29d30b9dc7621f 1164 Pfam PF13091 PLD-like domain 24 195 7.8E-16 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THSYN_RS24840 52155552c0e03267af29d30b9dc7621f 1164 Gene3D G3DSA:3.30.870.10 4 201 3.1E-9 T 29-03-2018 THSYN_RS24840 52155552c0e03267af29d30b9dc7621f 1164 SMART SM00490 747 839 9.8E-12 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS00890 6983312af5089f45ebd3fcfc886fa34a 365 SUPERFAMILY SSF52266 91 167 1.42E-7 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain THSYN_RS00890 6983312af5089f45ebd3fcfc886fa34a 365 SUPERFAMILY SSF52266 259 355 1.42E-7 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain THSYN_RS00890 6983312af5089f45ebd3fcfc886fa34a 365 Gene3D G3DSA:3.40.50.1110 91 357 2.6E-13 T 29-03-2018 THSYN_RS11800 8df18217b2df08fb829e11eee304500d 212 SUPERFAMILY SSF52540 1 72 5.01E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11800 8df18217b2df08fb829e11eee304500d 212 Gene3D G3DSA:3.40.50.300 1 184 8.0E-15 T 29-03-2018 THSYN_RS11800 8df18217b2df08fb829e11eee304500d 212 Pfam PF13476 AAA domain 6 169 5.9E-17 T 29-03-2018 THSYN_RS11755 d2f83d957029ee18fb8f18271a539e17 104 Pfam PF11743 Protein of unknown function (DUF3301) 6 93 5.7E-29 T 29-03-2018 IPR021732 Protein of unknown function DUF3301 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 Gene3D G3DSA:2.30.40.10 64 142 7.6E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 295 312 3.6E-35 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 334 350 3.6E-35 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 401 416 3.6E-35 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 427 440 3.6E-35 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 Pfam PF01979 Amidohydrolase family 125 453 4.4E-81 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 ProSitePatterns PS00145 Urease active site. 317 333 - T 29-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 SUPERFAMILY SSF51338 422 477 5.94E-6 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 SUPERFAMILY SSF51338 2 177 1.01E-60 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 567 4.1E-292 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 ProSitePatterns PS01120 Urease nickel ligands signature. 127 140 - T 29-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 Hamap MF_01953 Urease subunit alpha [ureC]. 2 567 56.918 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 119 2.8E-53 T 29-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 SUPERFAMILY SSF51556 481 567 3.4E-202 T 29-03-2018 IPR032466 Metal-dependent hydrolase THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 SUPERFAMILY SSF51556 129 432 3.4E-202 T 29-03-2018 IPR032466 Metal-dependent hydrolase THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 Gene3D G3DSA:3.20.20.140 143 421 8.1E-168 T 29-03-2018 THSYN_RS03785 17a506f293d9a8d494dd5d3319ae307b 567 Gene3D G3DSA:3.20.20.140 422 553 8.7E-43 T 29-03-2018 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 271 286 4.6E-22 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 106 120 4.6E-22 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 242 255 4.6E-22 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 225 4.6E-22 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 SUPERFAMILY SSF53738 183 293 1.1E-28 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 467 509 2.7E-6 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 SUPERFAMILY SSF53738 2 194 3.83E-47 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 107 116 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 14 153 9.8E-35 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 Gene3D G3DSA:3.40.120.10 1 187 5.9E-40 T 29-03-2018 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 Gene3D G3DSA:3.40.120.10 188 300 8.6E-30 T 29-03-2018 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 Gene3D G3DSA:3.30.310.50 403 544 8.4E-64 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 SUPERFAMILY SSF55957 410 544 3.66E-48 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 185 287 2.3E-11 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 295 407 9.8E-31 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 SUPERFAMILY SSF53738 279 415 4.32E-37 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS06640 45a07d2897ccc33d6265f17b01fa8451 544 Gene3D G3DSA:3.40.120.10 301 402 3.6E-38 T 29-03-2018 THSYN_RS09840 70096beb4ed182ed59cc506fbfbd9459 458 SUPERFAMILY SSF56601 112 375 3.18E-22 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS09840 70096beb4ed182ed59cc506fbfbd9459 458 Gene3D G3DSA:3.40.710.10 25 407 1.7E-27 T 29-03-2018 THSYN_RS13260 bfb08c234b380c33477050e177940591 428 Pfam PF00202 Aminotransferase class-III 23 422 3.7E-124 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THSYN_RS13260 bfb08c234b380c33477050e177940591 428 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 2 426 48.123 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 THSYN_RS13260 bfb08c234b380c33477050e177940591 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 244 281 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THSYN_RS13260 bfb08c234b380c33477050e177940591 428 Gene3D G3DSA:3.90.1150.10 1 176 5.0E-46 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS13260 bfb08c234b380c33477050e177940591 428 SUPERFAMILY SSF53383 6 425 5.9E-130 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS13260 bfb08c234b380c33477050e177940591 428 Gene3D G3DSA:3.40.640.10 188 317 2.9E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS13260 bfb08c234b380c33477050e177940591 428 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 15 423 7.5E-173 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 THSYN_RS13260 bfb08c234b380c33477050e177940591 428 Gene3D G3DSA:3.90.1150.10 318 426 6.7E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS24855 cd5ecd6e75d3e89d79d6a24735617d2d 489 Gene3D G3DSA:1.10.10.10 393 469 0.0011 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS24855 cd5ecd6e75d3e89d79d6a24735617d2d 489 Pfam PF04326 Putative DNA-binding domain 6 129 1.4E-7 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 THSYN_RS24855 cd5ecd6e75d3e89d79d6a24735617d2d 489 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 304 386 1.7E-16 T 29-03-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain THSYN_RS06270 fc690896378c0264206c79da9748611d 314 PIRSF PIRSF000428 7 305 3.7E-86 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS06270 fc690896378c0264206c79da9748611d 314 Pfam PF01515 Phosphate acetyl/butaryl transferase 84 297 2.5E-44 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS06270 fc690896378c0264206c79da9748611d 314 Gene3D G3DSA:3.40.50.10750 119 274 2.1E-45 T 29-03-2018 THSYN_RS06270 fc690896378c0264206c79da9748611d 314 SUPERFAMILY SSF53659 10 301 8.63E-67 T 29-03-2018 THSYN_RS25190 e272f3f746b00544c070eb7fbbf6c1b4 218 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 98 188 1.8E-15 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS25190 e272f3f746b00544c070eb7fbbf6c1b4 218 SUPERFAMILY SSF56784 4 188 4.41E-46 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS25190 e272f3f746b00544c070eb7fbbf6c1b4 218 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 2.5E-15 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS25190 e272f3f746b00544c070eb7fbbf6c1b4 218 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 170 2.5E-15 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS25190 e272f3f746b00544c070eb7fbbf6c1b4 218 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 2.5E-15 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS25190 e272f3f746b00544c070eb7fbbf6c1b4 218 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 132 148 2.5E-15 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS25190 e272f3f746b00544c070eb7fbbf6c1b4 218 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 106 182 8.6E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS25190 e272f3f746b00544c070eb7fbbf6c1b4 218 Gene3D G3DSA:3.40.50.1000 1 200 2.6E-34 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS25190 e272f3f746b00544c070eb7fbbf6c1b4 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 188 1.6E-34 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS26055 2f03d7183733fdd3040871d426fe2cff 77 Gene3D G3DSA:1.10.10.10 7 67 5.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26055 2f03d7183733fdd3040871d426fe2cff 77 SUPERFAMILY SSF46689 1 67 3.58E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS26055 2f03d7183733fdd3040871d426fe2cff 77 Pfam PF04255 Protein of unknown function (DUF433) 7 61 2.1E-21 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS26870 0e7a755ccb244a2718fd1102b7535cce 334 SMART SM00065 29 181 1.3E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS26870 0e7a755ccb244a2718fd1102b7535cce 334 Gene3D G3DSA:3.30.450.40 11 172 1.7E-20 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS26870 0e7a755ccb244a2718fd1102b7535cce 334 SUPERFAMILY SSF55781 15 168 8.51E-22 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS26870 0e7a755ccb244a2718fd1102b7535cce 334 Pfam PF13185 GAF domain 35 169 1.2E-11 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS22745 7417fe83459675513bde6edebd9aa619 328 Pfam PF00535 Glycosyl transferase family 2 21 193 1.4E-27 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS22745 7417fe83459675513bde6edebd9aa619 328 Gene3D G3DSA:3.90.550.10 13 319 8.6E-43 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22745 7417fe83459675513bde6edebd9aa619 328 SUPERFAMILY SSF53448 20 252 2.48E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS28265 ed9316eec0bbfb1e32e69b3400eb507e 102 Gene3D G3DSA:3.30.2310.20 1 90 9.6E-9 T 29-03-2018 THSYN_RS28265 ed9316eec0bbfb1e32e69b3400eb507e 102 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 89 3.3E-17 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS28265 ed9316eec0bbfb1e32e69b3400eb507e 102 SUPERFAMILY SSF143011 21 89 7.59E-8 T 29-03-2018 IPR035095 Toxin RelE-like domain THSYN_RS29685 ad9244aa6cde838c164f2811ae57955c 114 SUPERFAMILY SSF47729 3 92 8.68E-30 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS29685 ad9244aa6cde838c164f2811ae57955c 114 Gene3D G3DSA:4.10.520.10 1 99 2.9E-31 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS29685 ad9244aa6cde838c164f2811ae57955c 114 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 1.2E-15 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS29685 ad9244aa6cde838c164f2811ae57955c 114 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 1.2E-15 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS29685 ad9244aa6cde838c164f2811ae57955c 114 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 1.2E-15 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS29685 ad9244aa6cde838c164f2811ae57955c 114 Pfam PF00216 Bacterial DNA-binding protein 3 91 6.3E-30 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS29685 ad9244aa6cde838c164f2811ae57955c 114 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 95 7.6E-46 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 THSYN_RS29685 ad9244aa6cde838c164f2811ae57955c 114 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 29.254 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 THSYN_RS29685 ad9244aa6cde838c164f2811ae57955c 114 SMART SM00411 3 92 7.2E-39 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS23865 f458d2db6ac399fe631bb505692da04f 122 SMART SM01374 1 122 6.5E-86 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THSYN_RS23865 f458d2db6ac399fe631bb505692da04f 122 Gene3D G3DSA:2.40.150.20 1 122 1.1E-52 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THSYN_RS23865 f458d2db6ac399fe631bb505692da04f 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 1.5E-54 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THSYN_RS23865 f458d2db6ac399fe631bb505692da04f 122 SUPERFAMILY SSF50193 1 122 4.58E-52 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THSYN_RS23865 f458d2db6ac399fe631bb505692da04f 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 5.0E-58 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 THSYN_RS23865 f458d2db6ac399fe631bb505692da04f 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.521 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THSYN_RS23865 f458d2db6ac399fe631bb505692da04f 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 29-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS02265 1c803f7f97ff828836a11ef730c9e5f8 376 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 70 286 2.4E-19 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS02265 1c803f7f97ff828836a11ef730c9e5f8 376 SUPERFAMILY SSF111369 59 289 1.18E-27 T 29-03-2018 THSYN_RS02265 1c803f7f97ff828836a11ef730c9e5f8 376 Gene3D G3DSA:1.10.287.470 125 174 2.9E-9 T 29-03-2018 THSYN_RS02265 1c803f7f97ff828836a11ef730c9e5f8 376 Gene3D G3DSA:2.40.50.100 175 351 7.9E-10 T 29-03-2018 THSYN_RS02265 1c803f7f97ff828836a11ef730c9e5f8 376 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 47 354 8.1E-64 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS02265 1c803f7f97ff828836a11ef730c9e5f8 376 Gene3D G3DSA:2.40.50.100 69 124 9.7E-13 T 29-03-2018 THSYN_RS16925 8fb222d8d1c17f4576d9da282e804344 85 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 15 56 3.0E-8 T 29-03-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 THSYN_RS16925 8fb222d8d1c17f4576d9da282e804344 85 SMART SM00966 14 60 1.2E-6 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS16925 8fb222d8d1c17f4576d9da282e804344 85 Gene3D G3DSA:2.10.260.10 13 57 3.6E-10 T 29-03-2018 THSYN_RS16925 8fb222d8d1c17f4576d9da282e804344 85 SUPERFAMILY SSF89447 11 49 1.03E-8 T 29-03-2018 THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 SUPERFAMILY SSF46689 428 488 3.76E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 253 268 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 Gene3D G3DSA:1.10.8.60 340 448 1.5E-20 T 29-03-2018 THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 SUPERFAMILY SSF52172 7 211 3.27E-37 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 SUPERFAMILY SSF52540 175 408 1.89E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 SMART SM00448 8 119 1.0E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 380 389 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 Pfam PF00072 Response regulator receiver domain 10 119 1.0E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 191 204 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 452 469 6.0E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 469 489 6.0E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 Gene3D G3DSA:1.10.10.60 449 493 1.5E-15 T 29-03-2018 THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 SMART SM00382 187 330 2.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 Pfam PF02954 Bacterial regulatory protein, Fis family 446 486 7.9E-14 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 Gene3D G3DSA:3.40.50.300 165 339 1.2E-26 T 29-03-2018 THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 Pfam PF00158 Sigma-54 interaction domain 173 331 2.7E-66 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THSYN_RS01400 6cd1a659859bff7908742666e241cba6 494 Gene3D G3DSA:3.40.50.2300 1 164 3.2E-32 T 29-03-2018 THSYN_RS08965 04b4c608e1e8ea9a00b72186a31ba0bf 494 Gene3D G3DSA:3.40.50.1980 76 209 8.5E-39 T 29-03-2018 THSYN_RS08965 04b4c608e1e8ea9a00b72186a31ba0bf 494 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 81 88 - T 29-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 THSYN_RS08965 04b4c608e1e8ea9a00b72186a31ba0bf 494 TIGRFAM TIGR01862 N2-ase-Ialpha: nitrogenase component I, alpha chain 27 473 1.6E-200 T 29-03-2018 IPR010143 Nitrogenase component 1, alpha chain GO:0009399|GO:0016163|GO:0051536|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 THSYN_RS08965 04b4c608e1e8ea9a00b72186a31ba0bf 494 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 62 467 1.5E-110 T 29-03-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 THSYN_RS08965 04b4c608e1e8ea9a00b72186a31ba0bf 494 SUPERFAMILY SSF53807 7 479 1.19E-165 T 29-03-2018 THSYN_RS08965 04b4c608e1e8ea9a00b72186a31ba0bf 494 TIGRFAM TIGR01282 nifD: nitrogenase molybdenum-iron protein alpha chain 12 479 2.1E-264 T 29-03-2018 IPR005972 Nitrogenase molybdenum-iron protein alpha chain GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 THSYN_RS08965 04b4c608e1e8ea9a00b72186a31ba0bf 494 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 152 166 - T 29-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 THSYN_RS08965 04b4c608e1e8ea9a00b72186a31ba0bf 494 Gene3D G3DSA:3.40.50.1980 389 479 3.9E-29 T 29-03-2018 THSYN_RS08965 04b4c608e1e8ea9a00b72186a31ba0bf 494 Gene3D G3DSA:3.40.50.1980 312 388 3.8E-26 T 29-03-2018 THSYN_RS08965 04b4c608e1e8ea9a00b72186a31ba0bf 494 Gene3D G3DSA:3.40.50.1980 1 75 4.6E-20 T 29-03-2018 THSYN_RS08965 04b4c608e1e8ea9a00b72186a31ba0bf 494 Gene3D G3DSA:3.40.50.1980 210 311 2.2E-28 T 29-03-2018 THSYN_RS01730 7c8206b176bb943477731ed77a7af63c 394 SUPERFAMILY SSF52440 3 112 1.58E-32 T 29-03-2018 IPR016185 Pre-ATP-grasp domain THSYN_RS01730 7c8206b176bb943477731ed77a7af63c 394 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 14 391 6.7E-182 T 29-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 THSYN_RS01730 7c8206b176bb943477731ed77a7af63c 394 Gene3D G3DSA:3.40.50.20 9 126 4.4E-22 T 29-03-2018 THSYN_RS01730 7c8206b176bb943477731ed77a7af63c 394 Pfam PF02222 ATP-grasp domain 123 295 2.5E-56 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type THSYN_RS01730 7c8206b176bb943477731ed77a7af63c 394 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 8 392 52.666 T 29-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 THSYN_RS01730 7c8206b176bb943477731ed77a7af63c 394 Gene3D G3DSA:3.30.1490.20 127 196 8.0E-18 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS01730 7c8206b176bb943477731ed77a7af63c 394 Gene3D G3DSA:3.30.470.20 197 391 2.0E-46 T 29-03-2018 THSYN_RS01730 7c8206b176bb943477731ed77a7af63c 394 SUPERFAMILY SSF56059 120 384 5.3E-59 T 29-03-2018 THSYN_RS27000 d38d69cc3238aefd41105f1edaa76bd7 1141 Pfam PF13020 Domain of unknown function (DUF3883) 1018 1111 6.5E-17 T 29-03-2018 IPR024975 Domain of unknown function DUF3883 THSYN_RS27000 d38d69cc3238aefd41105f1edaa76bd7 1141 Pfam PF00176 SNF2 family N-terminal domain 123 296 5.4E-17 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THSYN_RS27000 d38d69cc3238aefd41105f1edaa76bd7 1141 Pfam PF00271 Helicase conserved C-terminal domain 488 592 1.9E-16 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS27000 d38d69cc3238aefd41105f1edaa76bd7 1141 Gene3D G3DSA:3.40.50.10810 93 330 1.5E-27 T 29-03-2018 THSYN_RS27000 d38d69cc3238aefd41105f1edaa76bd7 1141 SMART SM00490 506 592 1.4E-17 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS27000 d38d69cc3238aefd41105f1edaa76bd7 1141 SUPERFAMILY SSF52540 151 309 2.51E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27000 d38d69cc3238aefd41105f1edaa76bd7 1141 SUPERFAMILY SSF52540 474 611 2.51E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27000 d38d69cc3238aefd41105f1edaa76bd7 1141 SMART SM00487 98 296 9.6E-20 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS27000 d38d69cc3238aefd41105f1edaa76bd7 1141 Gene3D G3DSA:3.40.50.300 462 687 2.2E-28 T 29-03-2018 THSYN_RS27175 3aa03785ab064b3c27f13e73d46ca66b 285 SUPERFAMILY SSF161111 2 199 5.36E-53 T 29-03-2018 THSYN_RS27175 3aa03785ab064b3c27f13e73d46ca66b 285 Pfam PF01545 Cation efflux family 6 198 4.5E-43 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THSYN_RS27175 3aa03785ab064b3c27f13e73d46ca66b 285 SUPERFAMILY SSF160240 205 279 5.49E-21 T 29-03-2018 THSYN_RS27175 3aa03785ab064b3c27f13e73d46ca66b 285 Gene3D G3DSA:3.30.70.1350 199 281 2.3E-21 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain THSYN_RS27175 3aa03785ab064b3c27f13e73d46ca66b 285 Gene3D G3DSA:1.20.1510.10 1 198 3.9E-39 T 29-03-2018 THSYN_RS27175 3aa03785ab064b3c27f13e73d46ca66b 285 Pfam PF16916 Dimerisation domain of Zinc Transporter 206 278 3.9E-22 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain THSYN_RS27175 3aa03785ab064b3c27f13e73d46ca66b 285 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 5 279 5.3E-66 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THSYN_RS27860 b988722a43d9e3073421a2c903467652 2159 SUPERFAMILY SSF48239 1692 1891 2.64E-13 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid THSYN_RS27860 b988722a43d9e3073421a2c903467652 2159 Gene3D G3DSA:2.60.40.10 1018 1281 0.49 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS27860 b988722a43d9e3073421a2c903467652 2159 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 1282 1419 1.4E-10 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 THSYN_RS27860 b988722a43d9e3073421a2c903467652 2159 Pfam PF01835 MG2 domain 909 1014 8.9E-20 T 29-03-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 THSYN_RS27860 b988722a43d9e3073421a2c903467652 2159 Pfam PF00207 Alpha-2-macroglobulin family 1487 1568 1.0E-6 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 THSYN_RS27860 b988722a43d9e3073421a2c903467652 2159 Gene3D G3DSA:1.50.10.20 1682 1999 2.1E-14 T 29-03-2018 THSYN_RS27860 b988722a43d9e3073421a2c903467652 2159 Gene3D G3DSA:2.60.40.1120 818 864 0.0045 T 29-03-2018 THSYN_RS27860 b988722a43d9e3073421a2c903467652 2159 SMART SM01360 1486 1575 1.7E-6 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 THSYN_RS27860 b988722a43d9e3073421a2c903467652 2159 Gene3D G3DSA:2.60.40.10 1537 1639 2.7E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS27860 b988722a43d9e3073421a2c903467652 2159 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 800 900 5.8E-19 T 29-03-2018 THSYN_RS27860 b988722a43d9e3073421a2c903467652 2159 SMART SM01359 1281 1420 2.4E-25 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 THSYN_RS27860 b988722a43d9e3073421a2c903467652 2159 Gene3D G3DSA:2.60.40.10 910 1003 1.4E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS25235 12136e4f8b09244897b4cf7786750f21 122 SUPERFAMILY SSF158446 3 114 4.19E-36 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS25235 12136e4f8b09244897b4cf7786750f21 122 Pfam PF05635 23S rRNA-intervening sequence protein 6 105 2.5E-37 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS25235 12136e4f8b09244897b4cf7786750f21 122 TIGRFAM TIGR02436 TIGR02436: four helix bundle protein 9 114 6.0E-38 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS25235 12136e4f8b09244897b4cf7786750f21 122 Gene3D G3DSA:1.20.1440.60 1 119 7.3E-37 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 Gene3D G3DSA:3.30.450.40 420 546 0.12 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 SUPERFAMILY SSF55073 544 702 9.42E-39 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 SUPERFAMILY SSF55781 331 508 4.49E-42 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 SUPERFAMILY SSF55785 7 124 1.83E-28 T 29-03-2018 IPR000014 PAS domain THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 Gene3D G3DSA:3.30.450.20 6 125 1.1E-18 T 29-03-2018 THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 SMART SM00267 528 703 6.9E-52 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 Pfam PF00990 Diguanylate cyclase, GGDEF domain 539 699 2.2E-32 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 Pfam PF00360 Phytochrome region 336 514 3.1E-42 T 29-03-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 SMART SM00065 151 332 4.0E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 Pfam PF01590 GAF domain 155 321 9.5E-18 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 Gene3D G3DSA:3.30.450.40 141 322 4.5E-35 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 536 703 1.6E-36 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 Gene3D G3DSA:3.30.70.270 547 704 4.1E-47 T 29-03-2018 THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 PRINTS PR01033 Phytochrome signature 256 277 3.1E-18 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 PRINTS PR01033 Phytochrome signature 166 185 3.1E-18 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 PRINTS PR01033 Phytochrome signature 476 494 3.1E-18 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 PRINTS PR01033 Phytochrome signature 443 462 3.1E-18 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 SUPERFAMILY SSF55781 144 319 8.72E-51 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS31225 c292d6f764c0604de339d7596b900e62 704 Pfam PF08446 PAS fold 17 124 8.2E-17 T 29-03-2018 IPR013654 PAS fold-2 GO:0006355 THSYN_RS06510 a5a09a5130aa69ad03ca3cc539b8e5a0 608 Gene3D G3DSA:2.40.50.140 552 608 1.3E-5 T 29-03-2018 THSYN_RS06510 a5a09a5130aa69ad03ca3cc539b8e5a0 608 SUPERFAMILY SSF50249 178 546 7.71E-82 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS06510 a5a09a5130aa69ad03ca3cc539b8e5a0 608 Gene3D G3DSA:1.10.10.10 157 219 8.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS06510 a5a09a5130aa69ad03ca3cc539b8e5a0 608 SMART SM00955 232 504 2.5E-64 T 29-03-2018 THSYN_RS06510 a5a09a5130aa69ad03ca3cc539b8e5a0 608 Pfam PF00773 RNB domain 232 503 4.3E-49 T 29-03-2018 THSYN_RS06510 a5a09a5130aa69ad03ca3cc539b8e5a0 608 SUPERFAMILY SSF50249 548 606 1.11E-6 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS25050 f6a9e5c4869d68b5c6fb1c2d6f1692a7 639 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 564 6.5E-132 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS25050 f6a9e5c4869d68b5c6fb1c2d6f1692a7 639 Pfam PF00733 Asparagine synthase 240 629 5.4E-81 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THSYN_RS25050 f6a9e5c4869d68b5c6fb1c2d6f1692a7 639 Pfam PF13537 Glutamine amidotransferase domain 46 165 4.8E-42 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain THSYN_RS25050 f6a9e5c4869d68b5c6fb1c2d6f1692a7 639 Gene3D G3DSA:3.60.20.10 1 220 8.3E-50 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS25050 f6a9e5c4869d68b5c6fb1c2d6f1692a7 639 SUPERFAMILY SSF52402 482 627 2.07E-73 T 29-03-2018 THSYN_RS25050 f6a9e5c4869d68b5c6fb1c2d6f1692a7 639 SUPERFAMILY SSF52402 218 384 2.07E-73 T 29-03-2018 THSYN_RS25050 f6a9e5c4869d68b5c6fb1c2d6f1692a7 639 Gene3D G3DSA:3.40.50.620 221 634 6.1E-73 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS25050 f6a9e5c4869d68b5c6fb1c2d6f1692a7 639 PIRSF PIRSF001589 1 638 2.2E-152 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS25050 f6a9e5c4869d68b5c6fb1c2d6f1692a7 639 SUPERFAMILY SSF56235 1 222 1.8E-59 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS32205 db040115ec026947791e93c411edb326 226 Pfam PF06245 Protein of unknown function (DUF1015) 2 221 1.8E-50 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 THSYN_RS00900 ebe855928fe8a76ab54f8858762af478 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 29-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THSYN_RS00900 ebe855928fe8a76ab54f8858762af478 389 PIRSF PIRSF001554 1 388 2.4E-147 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THSYN_RS00900 ebe855928fe8a76ab54f8858762af478 389 Pfam PF08442 ATP-grasp domain 2 203 7.2E-70 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THSYN_RS00900 ebe855928fe8a76ab54f8858762af478 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 8.1E-155 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THSYN_RS00900 ebe855928fe8a76ab54f8858762af478 389 SUPERFAMILY SSF52210 239 384 5.89E-51 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THSYN_RS00900 ebe855928fe8a76ab54f8858762af478 389 SUPERFAMILY SSF56059 1 238 4.71E-75 T 29-03-2018 THSYN_RS00900 ebe855928fe8a76ab54f8858762af478 389 Gene3D G3DSA:3.40.50.261 240 385 1.3E-40 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THSYN_RS00900 ebe855928fe8a76ab54f8858762af478 389 Gene3D G3DSA:3.30.470.20 97 239 5.2E-52 T 29-03-2018 THSYN_RS00900 ebe855928fe8a76ab54f8858762af478 389 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 41.843 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THSYN_RS00900 ebe855928fe8a76ab54f8858762af478 389 Pfam PF00549 CoA-ligase 262 381 3.1E-22 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THSYN_RS00900 ebe855928fe8a76ab54f8858762af478 389 Gene3D G3DSA:3.30.1490.20 21 96 5.1E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS10480 bbfdadb628be8649ed655e5c8293e897 323 SUPERFAMILY SSF51569 1 316 6.07E-109 T 29-03-2018 THSYN_RS10480 bbfdadb628be8649ed655e5c8293e897 323 TIGRFAM TIGR00874 talAB: transaldolase 2 317 8.0E-144 T 29-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 THSYN_RS10480 bbfdadb628be8649ed655e5c8293e897 323 Gene3D G3DSA:3.20.20.70 1 319 4.0E-111 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS10480 bbfdadb628be8649ed655e5c8293e897 323 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 13 314 2.5E-93 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 THSYN_RS10480 bbfdadb628be8649ed655e5c8293e897 323 ProSitePatterns PS01054 Transaldolase signature 1. 30 38 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 THSYN_RS10480 bbfdadb628be8649ed655e5c8293e897 323 Hamap MF_00492 Transaldolase [tal]. 1 320 48.29 T 29-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Gene3D G3DSA:3.30.450.20 386 527 6.9E-22 T 29-03-2018 THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Gene3D G3DSA:3.30.450.20 670 826 8.6E-21 T 29-03-2018 THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SUPERFAMILY SSF55073 829 986 3.37E-50 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Gene3D G3DSA:3.30.70.270 827 986 5.7E-61 T 29-03-2018 THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Pfam PF00990 Diguanylate cyclase, GGDEF domain 824 980 9.5E-47 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SMART SM00267 813 984 1.6E-67 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SUPERFAMILY SSF55781 500 675 7.85E-22 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SUPERFAMILY SSF55785 276 379 5.76E-31 T 29-03-2018 IPR000014 PAS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Gene3D G3DSA:3.10.580.10 108 189 7.5E-8 T 29-03-2018 THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SMART SM00116 132 179 89.0 T 29-03-2018 IPR000644 CBS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SMART SM00116 67 115 0.0015 T 29-03-2018 IPR000644 CBS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SMART SM00116 4 51 1.5E-8 T 29-03-2018 IPR000644 CBS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SMART SM00116 198 246 1.3 T 29-03-2018 IPR000644 CBS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 687 819 1.1E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 390 514 4.0E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 266 389 1.3E-24 T 29-03-2018 IPR000014 PAS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SUPERFAMILY SSF55785 699 820 1.42E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SUPERFAMILY SSF54631 1 114 1.2E-23 T 29-03-2018 THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SUPERFAMILY SSF141868 1001 1244 1.7E-70 T 29-03-2018 IPR001633 EAL domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Gene3D G3DSA:3.20.20.450 987 1244 1.9E-78 T 29-03-2018 IPR001633 EAL domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SMART SM00086 340 382 3.5E-7 T 29-03-2018 IPR001610 PAC motif THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SMART SM00086 468 510 1.3E-5 T 29-03-2018 IPR001610 PAC motif THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SMART SM00086 772 813 28.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SUPERFAMILY SSF54631 123 246 4.15E-13 T 29-03-2018 THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 822 983 2.3E-42 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Gene3D G3DSA:3.10.580.10 190 249 6.8E-5 T 29-03-2018 THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Pfam PF13185 GAF domain 534 675 2.7E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Gene3D G3DSA:3.30.450.40 528 669 3.4E-18 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Gene3D G3DSA:3.30.450.20 258 385 3.0E-34 T 29-03-2018 THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SUPERFAMILY SSF55785 379 508 1.43E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Gene3D G3DSA:3.20.20.70 1 107 1.2E-25 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Pfam PF13426 PAS domain 414 509 5.9E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Pfam PF13426 PAS domain 278 381 4.3E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Pfam PF13426 PAS domain 699 812 3.7E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SMART SM00065 532 684 0.002 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Pfam PF00571 CBS domain 1 49 8.8E-8 T 29-03-2018 IPR000644 CBS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Pfam PF00571 CBS domain 60 114 3.4E-7 T 29-03-2018 IPR000644 CBS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Pfam PF00571 CBS domain 195 244 0.0019 T 29-03-2018 IPR000644 CBS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SMART SM00052 994 1240 8.4E-81 T 29-03-2018 IPR001633 EAL domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 Pfam PF00563 EAL domain 1001 1233 2.8E-61 T 29-03-2018 IPR001633 EAL domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SMART SM00091 268 334 2.3E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SMART SM00091 688 754 2.7E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS33270 fcf230a0cb17981d867229c0637399ce 1266 SMART SM00091 394 462 2.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS00150 b5d848013f05c838adc9e52d5fb052c7 647 SUPERFAMILY SSF51735 144 274 1.42E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS00150 b5d848013f05c838adc9e52d5fb052c7 647 Gene3D G3DSA:3.40.50.720 141 267 4.8E-30 T 29-03-2018 THSYN_RS00150 b5d848013f05c838adc9e52d5fb052c7 647 SUPERFAMILY SSF51735 285 551 1.84E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS00150 b5d848013f05c838adc9e52d5fb052c7 647 Gene3D G3DSA:3.40.50.720 279 580 1.8E-63 T 29-03-2018 THSYN_RS00150 b5d848013f05c838adc9e52d5fb052c7 647 Pfam PF02719 Polysaccharide biosynthesis protein 286 573 9.0E-113 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain THSYN_RS00150 b5d848013f05c838adc9e52d5fb052c7 647 Pfam PF13727 CoA-binding domain 65 241 5.1E-18 T 29-03-2018 THSYN_RS30755 8228b249575e94a949e2f3ca3d7a5c8e 290 SUPERFAMILY SSF55729 5 269 4.58E-34 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS30755 8228b249575e94a949e2f3ca3d7a5c8e 290 Gene3D G3DSA:3.40.630.30 144 282 2.8E-4 T 29-03-2018 THSYN_RS30755 8228b249575e94a949e2f3ca3d7a5c8e 290 Gene3D G3DSA:3.40.630.30 1 139 2.7E-19 T 29-03-2018 THSYN_RS30755 8228b249575e94a949e2f3ca3d7a5c8e 290 Pfam PF00583 Acetyltransferase (GNAT) family 25 99 5.2E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS00255 394322850647b9634f1c10b04541f242 406 Pfam PF00764 Arginosuccinate synthase 10 400 4.1E-152 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS00255 394322850647b9634f1c10b04541f242 406 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 12 20 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS00255 394322850647b9634f1c10b04541f242 406 Gene3D G3DSA:1.20.5.470 372 404 2.8E-15 T 29-03-2018 THSYN_RS00255 394322850647b9634f1c10b04541f242 406 SUPERFAMILY SSF52402 7 212 1.57E-50 T 29-03-2018 THSYN_RS00255 394322850647b9634f1c10b04541f242 406 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 120 131 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS00255 394322850647b9634f1c10b04541f242 406 Gene3D G3DSA:3.90.1260.10 166 360 1.1E-96 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS00255 394322850647b9634f1c10b04541f242 406 Gene3D G3DSA:3.40.50.620 2 165 7.8E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS00255 394322850647b9634f1c10b04541f242 406 Hamap MF_00005 Argininosuccinate synthase [argG]. 6 406 52.151 T 29-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS00255 394322850647b9634f1c10b04541f242 406 SUPERFAMILY SSF69864 180 404 7.32E-93 T 29-03-2018 THSYN_RS00255 394322850647b9634f1c10b04541f242 406 TIGRFAM TIGR00032 argG: argininosuccinate synthase 8 403 4.9E-142 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS01120 407f1c37c9b6b15d6e461496de964b3d 419 Pfam PF04326 Putative DNA-binding domain 14 131 2.1E-15 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 THSYN_RS01120 407f1c37c9b6b15d6e461496de964b3d 419 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 324 409 1.6E-16 T 29-03-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain THSYN_RS27745 82f89242cdcde24a802849fbbfe2d616 246 Pfam PF04754 Putative transposase, YhgA-like 1 130 7.5E-22 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS27745 82f89242cdcde24a802849fbbfe2d616 246 Pfam PF14261 Domain of unknown function (DUF4351) 190 225 8.7E-6 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS13325 db68d26b14390b3cae035ff6cfd8d934 298 Pfam PF12784 PD-(D/E)XK nuclease family transposase 9 125 3.2E-19 T 29-03-2018 THSYN_RS13325 db68d26b14390b3cae035ff6cfd8d934 298 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 9 295 2.7E-24 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA THSYN_RS13325 db68d26b14390b3cae035ff6cfd8d934 298 Gene3D G3DSA:1.10.10.60 246 295 5.9E-8 T 29-03-2018 THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 SUPERFAMILY SSF55874 723 889 1.09E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 SUPERFAMILY SSF47384 654 734 1.86E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 Pfam PF13493 Domain of unknown function (DUF4118) 405 509 1.1E-28 T 29-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 Pfam PF13492 GAF domain 532 648 8.5E-11 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 Gene3D G3DSA:1.20.120.620 404 502 8.2E-26 T 29-03-2018 THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 Gene3D G3DSA:3.40.50.620 229 375 3.6E-9 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 Gene3D G3DSA:1.10.287.130 660 728 4.5E-14 T 29-03-2018 THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 Gene3D G3DSA:3.40.50.300 23 147 2.4E-19 T 29-03-2018 THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 Pfam PF00512 His Kinase A (phospho-acceptor) domain 668 734 3.2E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 SMART SM00387 778 889 1.6E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 SMART SM00388 667 734 1.1E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 Gene3D G3DSA:3.30.565.10 729 889 3.1E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 783 887 2.8E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 Gene3D G3DSA:3.30.450.40 503 659 4.1E-7 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 24 232 3.7E-95 T 29-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 PRINTS PR00344 Bacterial sensor protein C-terminal signature 849 867 2.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 PRINTS PR00344 Bacterial sensor protein C-terminal signature 873 886 2.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 PRINTS PR00344 Bacterial sensor protein C-terminal signature 816 830 2.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08465 4edf8ffec3fab8a5eac41e3c97e7a5ad 902 SUPERFAMILY SSF52402 254 367 4.52E-7 T 29-03-2018 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 SUPERFAMILY SSF48113 434 738 1.62E-112 T 29-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 ProSitePatterns PS00436 Peroxidases active site signature. 97 108 - T 29-03-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 Pfam PF00141 Peroxidase 89 399 2.3E-49 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 Pfam PF00141 Peroxidase 407 713 1.9E-38 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 260 270 - T 29-03-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 Gene3D G3DSA:1.10.520.10 63 219 9.5E-37 T 29-03-2018 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 Hamap MF_01961 Catalase-peroxidase [katG]. 19 740 41.092 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 Gene3D G3DSA:1.10.520.10 445 606 2.8E-43 T 29-03-2018 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 SUPERFAMILY SSF48113 31 433 1.21E-145 T 29-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 PRINTS PR00458 Haem peroxidase superfamily signature 175 187 2.9E-16 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 PRINTS PR00458 Haem peroxidase superfamily signature 260 275 2.9E-16 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 PRINTS PR00458 Haem peroxidase superfamily signature 157 174 2.9E-16 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 PRINTS PR00458 Haem peroxidase superfamily signature 97 111 2.9E-16 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 PRINTS PR00458 Haem peroxidase superfamily signature 320 335 2.9E-16 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 59 72 4.0E-46 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 268 291 4.0E-46 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 484 510 4.0E-46 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 74 99 4.0E-46 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 33 55 4.0E-46 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 Gene3D G3DSA:1.10.420.10 607 715 5.6E-37 T 29-03-2018 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 Gene3D G3DSA:1.10.420.10 234 401 2.1E-37 T 29-03-2018 THSYN_RS02275 37b1b0c11c751d091ad29d2402bd1304 742 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 33 740 0.0 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THSYN_RS31240 a23584fdab3bc633068d403694f5be28 703 Pfam PF11067 Protein of unknown function (DUF2868) 204 686 3.1E-85 T 29-03-2018 IPR021296 Protein of unknown function DUF2868 THSYN_RS31240 a23584fdab3bc633068d403694f5be28 703 PRINTS PR01217 Proline rich extensin signature 481 506 3.5E-10 T 29-03-2018 THSYN_RS31240 a23584fdab3bc633068d403694f5be28 703 PRINTS PR01217 Proline rich extensin signature 407 428 3.5E-10 T 29-03-2018 THSYN_RS31240 a23584fdab3bc633068d403694f5be28 703 PRINTS PR01217 Proline rich extensin signature 428 444 3.5E-10 T 29-03-2018 THSYN_RS31240 a23584fdab3bc633068d403694f5be28 703 PRINTS PR01217 Proline rich extensin signature 446 463 3.5E-10 T 29-03-2018 THSYN_RS22250 f220dc3234c5dc2fe4db46bf207644b0 494 SUPERFAMILY SSF90257 14 133 6.28E-5 T 29-03-2018 THSYN_RS22250 f220dc3234c5dc2fe4db46bf207644b0 494 Gene3D G3DSA:3.90.1580.10 258 327 3.9E-12 T 29-03-2018 THSYN_RS22250 f220dc3234c5dc2fe4db46bf207644b0 494 Gene3D G3DSA:3.90.1580.10 328 494 1.4E-46 T 29-03-2018 THSYN_RS22250 f220dc3234c5dc2fe4db46bf207644b0 494 Gene3D G3DSA:1.20.1170.10 7 156 6.1E-11 T 29-03-2018 THSYN_RS22250 f220dc3234c5dc2fe4db46bf207644b0 494 SUPERFAMILY SSF56436 267 493 5.18E-63 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS22250 f220dc3234c5dc2fe4db46bf207644b0 494 Pfam PF03781 Sulfatase-modifying factor enzyme 1 268 492 8.9E-56 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS23375 334993c540a3f1b953e22a17626e44d3 699 SMART SM00245 327 545 1.1E-58 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 THSYN_RS23375 334993c540a3f1b953e22a17626e44d3 699 Pfam PF03572 Peptidase family S41 361 543 1.5E-49 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 THSYN_RS23375 334993c540a3f1b953e22a17626e44d3 699 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 242 317 1.6E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS23375 334993c540a3f1b953e22a17626e44d3 699 SMART SM00228 244 322 5.4E-4 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS23375 334993c540a3f1b953e22a17626e44d3 699 Gene3D G3DSA:2.30.42.10 252 340 7.7E-11 T 29-03-2018 THSYN_RS23375 334993c540a3f1b953e22a17626e44d3 699 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 194 560 6.0E-88 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 THSYN_RS23375 334993c540a3f1b953e22a17626e44d3 699 SUPERFAMILY SSF52096 185 262 2.49E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS23375 334993c540a3f1b953e22a17626e44d3 699 SUPERFAMILY SSF52096 355 549 2.49E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS23375 334993c540a3f1b953e22a17626e44d3 699 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 549 685 4.1E-23 T 29-03-2018 IPR020992 Tail specific protease, C-terminal THSYN_RS23375 334993c540a3f1b953e22a17626e44d3 699 SUPERFAMILY SSF50156 242 318 5.0E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS23375 334993c540a3f1b953e22a17626e44d3 699 Gene3D G3DSA:3.30.750.44 153 251 1.2E-21 T 29-03-2018 THSYN_RS23375 334993c540a3f1b953e22a17626e44d3 699 Gene3D G3DSA:3.90.226.10 341 675 1.1E-52 T 29-03-2018 THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 203 2.0E-73 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 Gene3D G3DSA:3.40.50.880 4 217 3.9E-45 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 Gene3D G3DSA:3.30.300.10 404 528 2.8E-51 T 29-03-2018 THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 SUPERFAMILY SSF52402 192 449 1.15E-56 T 29-03-2018 THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 528 55.428 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 211 528 9.8E-148 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 SUPERFAMILY SSF52317 6 236 3.82E-54 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 Pfam PF02540 NAD synthase 216 291 7.3E-7 T 29-03-2018 IPR022310 NAD/GMP synthase THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 Pfam PF00958 GMP synthase C terminal domain 436 527 1.4E-41 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 6.4E-7 T 29-03-2018 THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 PRINTS PR00096 Glutamine amidotransferase superfamily signature 176 189 6.4E-7 T 29-03-2018 THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 6.4E-7 T 29-03-2018 THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 Pfam PF00117 Glutamine amidotransferase class-I 11 198 9.3E-36 T 29-03-2018 IPR017926 Glutamine amidotransferase THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 Gene3D G3DSA:3.40.50.620 218 403 4.8E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 SUPERFAMILY SSF54810 408 528 2.88E-49 T 29-03-2018 THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 PRINTS PR00097 Anthranilate synthase component II signature 53 62 9.1E-6 T 29-03-2018 THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 PRINTS PR00097 Anthranilate synthase component II signature 176 189 9.1E-6 T 29-03-2018 THSYN_RS23250 2b9da33fa9dccd7ef027e00ee811cdf8 528 PRINTS PR00097 Anthranilate synthase component II signature 80 91 9.1E-6 T 29-03-2018 THSYN_RS15115 112613482293360adf91618909d85f28 1135 Pfam PF01055 Glycosyl hydrolases family 31 275 766 1.9E-82 T 29-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 THSYN_RS15115 112613482293360adf91618909d85f28 1135 SMART SM01065 1035 1131 2.9E-23 T 29-03-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 THSYN_RS15115 112613482293360adf91618909d85f28 1135 SMART SM01065 927 1026 4.9E-22 T 29-03-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 THSYN_RS15115 112613482293360adf91618909d85f28 1135 SUPERFAMILY SSF49452 1034 1129 6.38E-22 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 THSYN_RS15115 112613482293360adf91618909d85f28 1135 Gene3D G3DSA:3.20.20.80 281 695 4.2E-70 T 29-03-2018 THSYN_RS15115 112613482293360adf91618909d85f28 1135 Gene3D G3DSA:2.60.40.10 1028 1134 3.3E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15115 112613482293360adf91618909d85f28 1135 Gene3D G3DSA:2.60.40.1760 62 280 4.0E-12 T 29-03-2018 THSYN_RS15115 112613482293360adf91618909d85f28 1135 Gene3D G3DSA:2.60.40.10 925 1025 4.4E-19 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15115 112613482293360adf91618909d85f28 1135 SUPERFAMILY SSF51011 676 754 6.33E-12 T 29-03-2018 THSYN_RS15115 112613482293360adf91618909d85f28 1135 SUPERFAMILY SSF49452 927 1018 2.01E-20 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 THSYN_RS15115 112613482293360adf91618909d85f28 1135 Gene3D G3DSA:2.60.40.1180 763 905 7.9E-16 T 29-03-2018 THSYN_RS15115 112613482293360adf91618909d85f28 1135 Pfam PF17137 Domain of unknown function (DUF5110) 790 862 1.4E-13 T 29-03-2018 IPR033403 Domain of unknown function DUF5110 THSYN_RS15115 112613482293360adf91618909d85f28 1135 Gene3D G3DSA:2.60.40.1180 696 762 1.2E-12 T 29-03-2018 THSYN_RS15115 112613482293360adf91618909d85f28 1135 SUPERFAMILY SSF74650 68 279 1.16E-6 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 THSYN_RS15115 112613482293360adf91618909d85f28 1135 SUPERFAMILY SSF51445 285 674 1.05E-35 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS15115 112613482293360adf91618909d85f28 1135 Pfam PF00686 Starch binding domain 928 1021 1.1E-21 T 29-03-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 THSYN_RS15115 112613482293360adf91618909d85f28 1135 Pfam PF00686 Starch binding domain 1036 1129 5.6E-21 T 29-03-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 THSYN_RS00920 6cfc96b826fde5a5cb666e6ef4290425 575 Gene3D G3DSA:1.20.1480.30 329 445 0.23 T 29-03-2018 THSYN_RS00920 6cfc96b826fde5a5cb666e6ef4290425 575 Gene3D G3DSA:1.20.58.130 248 328 0.0035 T 29-03-2018 THSYN_RS00920 6cfc96b826fde5a5cb666e6ef4290425 575 Gene3D G3DSA:3.30.1330.60 446 575 2.3E-35 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS00920 6cfc96b826fde5a5cb666e6ef4290425 575 Pfam PF00691 OmpA family 470 564 7.5E-18 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS00920 6cfc96b826fde5a5cb666e6ef4290425 575 Gene3D G3DSA:1.20.5.340 136 183 1.8E-4 T 29-03-2018 THSYN_RS00920 6cfc96b826fde5a5cb666e6ef4290425 575 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 553 573 9.6E-8 T 29-03-2018 THSYN_RS00920 6cfc96b826fde5a5cb666e6ef4290425 575 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 515 532 9.6E-8 T 29-03-2018 THSYN_RS00920 6cfc96b826fde5a5cb666e6ef4290425 575 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 533 552 9.6E-8 T 29-03-2018 THSYN_RS00920 6cfc96b826fde5a5cb666e6ef4290425 575 SUPERFAMILY SSF103088 466 570 3.01E-30 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS00920 6cfc96b826fde5a5cb666e6ef4290425 575 Gene3D G3DSA:1.20.5.340 31 135 1.5E-5 T 29-03-2018 THSYN_RS29880 9a6e3707820ea3f2710e81ad7c598faf 107 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 103 3.0E-19 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS29880 9a6e3707820ea3f2710e81ad7c598faf 107 Gene3D G3DSA:2.30.30.110 6 104 6.4E-17 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS29880 9a6e3707820ea3f2710e81ad7c598faf 107 SUPERFAMILY SSF50118 2 105 1.37E-24 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS00015 a65cf9737836f7d3efc71cf539427311 361 SUPERFAMILY SSF52540 9 330 1.01E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00015 a65cf9737836f7d3efc71cf539427311 361 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 7 355 3.0E-52 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 THSYN_RS00015 a65cf9737836f7d3efc71cf539427311 361 Gene3D G3DSA:3.40.50.300 5 358 6.1E-14 T 29-03-2018 THSYN_RS00015 a65cf9737836f7d3efc71cf539427311 361 ProSitePatterns PS00617 RecF protein signature 1. 121 141 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 THSYN_RS00015 a65cf9737836f7d3efc71cf539427311 361 Pfam PF13476 AAA domain 9 57 5.1E-7 T 29-03-2018 THSYN_RS00015 a65cf9737836f7d3efc71cf539427311 361 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 361 51.311 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 THSYN_RS22360 9c81af00407fd8101eb66381c4532887 230 Pfam PF07589 PEP-CTERM motif 201 225 3.1E-9 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS22360 9c81af00407fd8101eb66381c4532887 230 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 202 225 2.5E-6 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS03800 99cd3c1e227ad05e12b69803df814d1a 100 PIRSF PIRSF001223 1 100 3.3E-49 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03800 99cd3c1e227ad05e12b69803df814d1a 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 2.0E-30 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03800 99cd3c1e227ad05e12b69803df814d1a 100 Pfam PF00547 Urease, gamma subunit 2 99 7.9E-47 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03800 99cd3c1e227ad05e12b69803df814d1a 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.295 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03800 99cd3c1e227ad05e12b69803df814d1a 100 Gene3D G3DSA:3.30.280.10 2 99 2.8E-48 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03800 99cd3c1e227ad05e12b69803df814d1a 100 SUPERFAMILY SSF54111 2 99 4.71E-46 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03800 99cd3c1e227ad05e12b69803df814d1a 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 2 99 7.0E-53 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS00285 8e21b6d703af3734c15570458cd847df 378 SUPERFAMILY SSF52540 4 250 9.39E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00285 8e21b6d703af3734c15570458cd847df 378 Pfam PF08402 TOBE domain 290 362 7.0E-9 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THSYN_RS00285 8e21b6d703af3734c15570458cd847df 378 Gene3D G3DSA:2.40.50.140 302 354 1.3E-13 T 29-03-2018 THSYN_RS00285 8e21b6d703af3734c15570458cd847df 378 Gene3D G3DSA:3.40.50.300 2 247 1.4E-67 T 29-03-2018 THSYN_RS00285 8e21b6d703af3734c15570458cd847df 378 Pfam PF00005 ABC transporter 22 164 7.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS00285 8e21b6d703af3734c15570458cd847df 378 SMART SM00382 31 213 9.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS00285 8e21b6d703af3734c15570458cd847df 378 SUPERFAMILY SSF50331 245 369 1.08E-27 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal THSYN_RS00285 8e21b6d703af3734c15570458cd847df 378 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS00285 8e21b6d703af3734c15570458cd847df 378 Gene3D G3DSA:2.40.50.100 248 301 1.9E-8 T 29-03-2018 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 Gene3D G3DSA:1.10.4050.10 534 647 4.6E-18 T 29-03-2018 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 Gene3D G3DSA:1.10.4050.10 6 123 1.9E-9 T 29-03-2018 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 Gene3D G3DSA:3.30.460.10 648 821 1.8E-57 T 29-03-2018 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 Gene3D G3DSA:3.30.460.10 124 296 4.3E-62 T 29-03-2018 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 Gene3D G3DSA:1.20.120.330 297 452 8.3E-48 T 29-03-2018 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 Gene3D G3DSA:1.20.120.330 822 955 2.7E-39 T 29-03-2018 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 Pfam PF08335 GlnD PII-uridylyltransferase 309 448 3.8E-41 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 Pfam PF08335 GlnD PII-uridylyltransferase 835 923 2.9E-12 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 34 955 19.132 T 29-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 SUPERFAMILY SSF81301 37 298 1.21E-78 T 29-03-2018 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 SUPERFAMILY SSF81593 825 953 6.75E-31 T 29-03-2018 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 563 814 3.6E-80 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 41 287 7.4E-78 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 SUPERFAMILY SSF81301 535 825 1.01E-82 T 29-03-2018 THSYN_RS02645 67eca39e7b3a791e23638579da377387 955 SUPERFAMILY SSF81593 299 448 7.38E-44 T 29-03-2018 THSYN_RS11955 7cc4a12ee7ec2e07444f7ecc0d564bd5 408 Gene3D G3DSA:3.40.640.10 53 280 4.5E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS11955 7cc4a12ee7ec2e07444f7ecc0d564bd5 408 Gene3D G3DSA:3.90.1150.10 281 405 3.2E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS11955 7cc4a12ee7ec2e07444f7ecc0d564bd5 408 SUPERFAMILY SSF53383 6 400 1.33E-92 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS11955 7cc4a12ee7ec2e07444f7ecc0d564bd5 408 Pfam PF00155 Aminotransferase class I and II 34 386 5.7E-47 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THSYN_RS30375 d43da2e118cdb93d82242919ad64b336 174 Pfam PF13673 Acetyltransferase (GNAT) domain 29 147 3.1E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS30375 d43da2e118cdb93d82242919ad64b336 174 SUPERFAMILY SSF55729 1 165 3.72E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS30375 d43da2e118cdb93d82242919ad64b336 174 Gene3D G3DSA:3.40.630.30 11 170 1.1E-19 T 29-03-2018 THSYN_RS25350 d2f8292ab4246969611068fc24fd87c8 246 Pfam PF12644 Protein of unknown function (DUF3782) 84 165 1.5E-24 T 29-03-2018 IPR024271 Protein of unknown function DUF3782 THSYN_RS25350 d2f8292ab4246969611068fc24fd87c8 246 Pfam PF07788 PD-(D/E)XK nuclease superfamily 166 235 6.9E-24 T 29-03-2018 IPR012431 PD-(D/E)XK nuclease THSYN_RS28420 08d39669f70731ddfd618c907908d2a0 439 Gene3D G3DSA:3.40.50.300 217 438 2.0E-39 T 29-03-2018 THSYN_RS28420 08d39669f70731ddfd618c907908d2a0 439 Pfam PF00271 Helicase conserved C-terminal domain 235 341 1.2E-25 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS28420 08d39669f70731ddfd618c907908d2a0 439 SUPERFAMILY SSF52540 33 353 3.69E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS28420 08d39669f70731ddfd618c907908d2a0 439 Pfam PF00270 DEAD/DEAH box helicase 27 192 2.8E-45 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS28420 08d39669f70731ddfd618c907908d2a0 439 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site THSYN_RS28420 08d39669f70731ddfd618c907908d2a0 439 Gene3D G3DSA:3.40.50.300 10 215 1.6E-56 T 29-03-2018 THSYN_RS28420 08d39669f70731ddfd618c907908d2a0 439 SMART SM00487 22 223 2.8E-51 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS28420 08d39669f70731ddfd618c907908d2a0 439 SMART SM00490 260 341 2.8E-22 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 SUPERFAMILY SSF54001 177 401 9.25E-78 T 29-03-2018 THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 SUPERFAMILY SSF54001 32 137 9.25E-78 T 29-03-2018 THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 Gene3D G3DSA:3.90.70.10 209 396 4.6E-12 T 29-03-2018 THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 532 593 1.8E-5 T 29-03-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 648 706 4.0E-6 T 29-03-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 SMART SM00060 406 485 1.9E-10 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 Gene3D G3DSA:2.60.120.380 505 611 2.2E-13 T 29-03-2018 THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 Gene3D G3DSA:2.60.40.10 404 504 1.3E-20 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 ProDom PD004169 PRECURSOR CYSTEINE STREPTOCOCCAL STREPTOPAIN PROTEINASE PROTEASE THIOL B STREPTOCOCCUS EXOTOXIN 190 385 3.0E-27 T 29-03-2018 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 SUPERFAMILY SSF49265 400 497 5.08E-18 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 PRINTS PR00797 Streptopain (C10) cysteine protease family signature 331 355 2.0E-13 T 29-03-2018 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 PRINTS PR00797 Streptopain (C10) cysteine protease family signature 363 384 2.0E-13 T 29-03-2018 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 PRINTS PR00797 Streptopain (C10) cysteine protease family signature 207 231 2.0E-13 T 29-03-2018 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 Gene3D G3DSA:2.60.120.380 619 722 2.4E-12 T 29-03-2018 THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 Pfam PF00041 Fibronectin type III domain 408 485 3.8E-9 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 Pfam PF01640 Peptidase C10 family 189 377 4.0E-52 T 29-03-2018 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 THSYN_RS17475 00a6a1c13e9dd703150eab74e813de47 724 Pfam PF13734 Spi protease inhibitor 30 126 3.3E-15 T 29-03-2018 IPR025896 Spi protease inhibitor THSYN_RS22295 b0d7b2f28a57f1e52441eace56de8b33 496 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 169 1.9E-35 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THSYN_RS22295 b0d7b2f28a57f1e52441eace56de8b33 496 PRINTS PR00095 Anthranilate synthase component I signature 336 349 1.7E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THSYN_RS22295 b0d7b2f28a57f1e52441eace56de8b33 496 PRINTS PR00095 Anthranilate synthase component I signature 416 430 1.7E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THSYN_RS22295 b0d7b2f28a57f1e52441eace56de8b33 496 PRINTS PR00095 Anthranilate synthase component I signature 322 335 1.7E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THSYN_RS22295 b0d7b2f28a57f1e52441eace56de8b33 496 PRINTS PR00095 Anthranilate synthase component I signature 431 445 1.7E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THSYN_RS22295 b0d7b2f28a57f1e52441eace56de8b33 496 SUPERFAMILY SSF56322 14 482 5.49E-160 T 29-03-2018 IPR005801 ADC synthase GO:0009058 THSYN_RS22295 b0d7b2f28a57f1e52441eace56de8b33 496 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 26 482 2.4E-170 T 29-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THSYN_RS22295 b0d7b2f28a57f1e52441eace56de8b33 496 Pfam PF00425 chorismate binding enzyme 221 474 2.6E-97 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal THSYN_RS22295 b0d7b2f28a57f1e52441eace56de8b33 496 Gene3D G3DSA:3.60.120.10 13 484 1.1E-169 T 29-03-2018 IPR005801 ADC synthase GO:0009058 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Gene3D G3DSA:1.25.40.10 1171 1233 2.8E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SMART SM00028 742 775 3.2 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SMART SM00028 1030 1063 0.28 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SMART SM00028 1126 1159 7.2E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SMART SM00028 886 919 9.7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SMART SM00028 1078 1111 190.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SMART SM00028 982 1015 0.017 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SMART SM00028 790 823 0.3 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SMART SM00028 838 871 3.8 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SMART SM00028 1194 1227 63.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SMART SM00028 934 967 19.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SMART SM00028 1160 1193 2.3 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Gene3D G3DSA:1.25.40.10 972 1022 2.8E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Pfam PF13429 Tetratricopeptide repeat 990 1225 2.8E-7 T 29-03-2018 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Pfam PF13191 AAA ATPase domain 170 325 1.8E-8 T 29-03-2018 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Gene3D G3DSA:1.10.10.10 910 971 5.4E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Gene3D G3DSA:1.25.40.10 762 834 1.2E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Gene3D G3DSA:3.40.50.300 162 338 1.3E-8 T 29-03-2018 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Gene3D G3DSA:1.20.1250.10 835 909 2.4E-11 T 29-03-2018 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Gene3D G3DSA:1.25.40.10 1135 1170 9.9E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Gene3D G3DSA:1.25.40.10 673 761 3.1E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SUPERFAMILY SSF52540 262 411 1.99E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SUPERFAMILY SSF52540 164 235 1.99E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Gene3D G3DSA:1.10.150.200 1088 1134 0.42 T 29-03-2018 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Gene3D G3DSA:1.10.150.200 1023 1087 5.6E-6 T 29-03-2018 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SUPERFAMILY SSF48452 980 1059 1.9E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SUPERFAMILY SSF48452 761 923 1.9E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Pfam PF13181 Tetratricopeptide repeat 747 772 0.021 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Pfam PF13181 Tetratricopeptide repeat 843 868 0.013 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Pfam PF13181 Tetratricopeptide repeat 795 820 0.027 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 Pfam PF13181 Tetratricopeptide repeat 891 916 0.081 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23245 2ec7789092335839dc20e196fb53dc91 1276 SUPERFAMILY SSF48452 1031 1226 3.57E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS09780 3b660c8ba1cbd08f8c3720ac1e60126b 296 SUPERFAMILY SSF53474 9 288 4.19E-59 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS09780 3b660c8ba1cbd08f8c3720ac1e60126b 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 2.7E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS09780 3b660c8ba1cbd08f8c3720ac1e60126b 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 2.7E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS09780 3b660c8ba1cbd08f8c3720ac1e60126b 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 2.7E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS09780 3b660c8ba1cbd08f8c3720ac1e60126b 296 Gene3D G3DSA:3.40.50.1820 2 295 3.7E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS09780 3b660c8ba1cbd08f8c3720ac1e60126b 296 Pfam PF12697 Alpha/beta hydrolase family 27 274 4.8E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 SMART SM00304 326 380 1.5E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 SMART SM00052 687 935 2.4E-105 T 29-03-2018 IPR001633 EAL domain THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 Gene3D G3DSA:3.30.450.20 175 305 3.8E-14 T 29-03-2018 THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 SMART SM00086 465 507 2.6E-8 T 29-03-2018 IPR001610 PAC motif THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 Pfam PF00563 EAL domain 693 930 7.4E-74 T 29-03-2018 IPR001633 EAL domain THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 SUPERFAMILY SSF141868 692 940 3.92E-85 T 29-03-2018 IPR001633 EAL domain THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 SUPERFAMILY SSF55073 523 679 5.1E-44 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 Gene3D G3DSA:3.20.20.450 685 948 1.9E-96 T 29-03-2018 IPR001633 EAL domain THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 SMART SM00267 507 677 8.3E-57 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 386 514 2.2E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 SMART SM00091 390 458 1.3E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 Gene3D G3DSA:3.30.70.270 521 684 1.5E-58 T 29-03-2018 THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 Pfam PF00672 HAMP domain 328 376 1.2E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 SUPERFAMILY SSF55785 397 510 1.44E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 Pfam PF08447 PAS fold 413 500 2.2E-18 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 Pfam PF02743 Cache domain 43 287 2.0E-13 T 29-03-2018 IPR033479 Double Cache domain 1 THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 SUPERFAMILY SSF158472 328 376 3.66E-5 T 29-03-2018 THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 515 677 8.3E-40 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 Gene3D G3DSA:3.30.450.20 367 520 4.3E-34 T 29-03-2018 THSYN_RS16855 e9ad172ebf8e6f10de57dbba476c8835 961 Pfam PF00990 Diguanylate cyclase, GGDEF domain 518 672 1.4E-43 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS07980 6a2aecbd9c65a4dc3467ab1fd3822a6d 110 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 107 14.524 T 29-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 THSYN_RS07980 6a2aecbd9c65a4dc3467ab1fd3822a6d 110 Pfam PF02416 mttA/Hcf106 family 4 49 9.4E-9 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 THSYN_RS07980 6a2aecbd9c65a4dc3467ab1fd3822a6d 110 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 1.6E-19 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 THSYN_RS07980 6a2aecbd9c65a4dc3467ab1fd3822a6d 110 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 1.6E-19 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 THSYN_RS07980 6a2aecbd9c65a4dc3467ab1fd3822a6d 110 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 1.6E-19 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 THSYN_RS07980 6a2aecbd9c65a4dc3467ab1fd3822a6d 110 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 68 1.5E-24 T 29-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SUPERFAMILY SSF55073 802 958 2.43E-45 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 Gene3D G3DSA:3.30.450.20 235 358 1.5E-24 T 29-03-2018 THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SMART SM00267 786 959 1.7E-57 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 Pfam PF08447 PAS fold 523 610 5.1E-21 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SUPERFAMILY SSF55785 483 614 7.5E-26 T 29-03-2018 IPR000014 PAS domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 360 493 3.4E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 125 231 2.1E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 494 623 2.3E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 235 357 9.5E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SUPERFAMILY SSF55785 349 484 3.66E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SUPERFAMILY SSF55781 638 791 1.41E-8 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 793 958 1.4E-51 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SMART SM00086 443 486 0.83 T 29-03-2018 IPR001610 PAC motif THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SMART SM00086 573 616 9.8E-7 T 29-03-2018 IPR001610 PAC motif THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SMART SM00086 310 352 5.6 T 29-03-2018 IPR001610 PAC motif THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SMART SM00086 185 226 3.9 T 29-03-2018 IPR001610 PAC motif THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SUPERFAMILY SSF55785 132 233 1.56E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 Pfam PF08448 PAS fold 244 353 4.2E-13 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 Pfam PF13426 PAS domain 128 225 2.3E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 Pfam PF13188 PAS domain 364 410 4.0E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 Gene3D G3DSA:3.30.70.270 796 961 6.6E-54 T 29-03-2018 THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 Gene3D G3DSA:3.30.450.20 359 483 3.8E-25 T 29-03-2018 THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 Gene3D G3DSA:3.30.450.20 484 635 2.3E-39 T 29-03-2018 THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 Gene3D G3DSA:3.30.450.20 103 234 2.3E-17 T 29-03-2018 THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 Pfam PF00990 Diguanylate cyclase, GGDEF domain 797 955 3.7E-43 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 Gene3D G3DSA:3.30.450.40 636 795 3.5E-13 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SUPERFAMILY SSF55785 223 350 2.74E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SMART SM00091 364 434 0.0047 T 29-03-2018 IPR000014 PAS domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SMART SM00091 238 304 3.8E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SMART SM00091 113 177 0.74 T 29-03-2018 IPR000014 PAS domain THSYN_RS21130 88430836c7cb58a93c347232e206d43d 961 SMART SM00091 498 566 1.5E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS25655 a67c5232f26368e6048f1defb5d9da68 262 Pfam PF01026 TatD related DNase 4 251 8.8E-63 T 29-03-2018 IPR001130 TatD family GO:0016788 THSYN_RS25655 a67c5232f26368e6048f1defb5d9da68 262 PIRSF PIRSF005902 1 256 7.6E-64 T 29-03-2018 IPR001130 TatD family GO:0016788 THSYN_RS25655 a67c5232f26368e6048f1defb5d9da68 262 SUPERFAMILY SSF51556 3 253 4.54E-77 T 29-03-2018 IPR032466 Metal-dependent hydrolase THSYN_RS25655 a67c5232f26368e6048f1defb5d9da68 262 Gene3D G3DSA:3.20.20.140 1 260 1.3E-75 T 29-03-2018 THSYN_RS25655 a67c5232f26368e6048f1defb5d9da68 262 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 125 135 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THSYN_RS25655 a67c5232f26368e6048f1defb5d9da68 262 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 3 11 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THSYN_RS05700 659e7bcfce531caa770d5e8b30523fda 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 3.0E-15 T 29-03-2018 THSYN_RS05700 659e7bcfce531caa770d5e8b30523fda 144 SUPERFAMILY SSF54747 3 73 6.8E-31 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal THSYN_RS05700 659e7bcfce531caa770d5e8b30523fda 144 Gene3D G3DSA:1.10.10.250 73 141 3.4E-22 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 THSYN_RS05700 659e7bcfce531caa770d5e8b30523fda 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 8.1E-23 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 THSYN_RS05700 659e7bcfce531caa770d5e8b30523fda 144 SUPERFAMILY SSF46906 68 141 5.49E-25 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 THSYN_RS05700 659e7bcfce531caa770d5e8b30523fda 144 Gene3D G3DSA:3.30.1550.10 3 72 1.2E-35 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal THSYN_RS05700 659e7bcfce531caa770d5e8b30523fda 144 SMART SM00649 9 141 1.3E-83 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 THSYN_RS05700 659e7bcfce531caa770d5e8b30523fda 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 4.6E-64 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS05700 659e7bcfce531caa770d5e8b30523fda 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 4.2E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal THSYN_RS05700 659e7bcfce531caa770d5e8b30523fda 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 29-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS05700 659e7bcfce531caa770d5e8b30523fda 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.141 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 THSYN_RS29315 2f0f8b31c600baa7125ec6f8999dc15d 307 Pfam PF03055 Retinal pigment epithelial membrane protein 21 288 1.6E-57 T 29-03-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 THSYN_RS12140 2bcad67042e3d00cff5c774178816943 241 SUPERFAMILY SSF81606 5 239 1.31E-49 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS12140 2bcad67042e3d00cff5c774178816943 241 SMART SM00331 7 240 9.1E-16 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS12140 2bcad67042e3d00cff5c774178816943 241 SMART SM00332 2 238 2.7E-11 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS12140 2bcad67042e3d00cff5c774178816943 241 Pfam PF13672 Protein phosphatase 2C 17 200 7.1E-17 T 29-03-2018 THSYN_RS12140 2bcad67042e3d00cff5c774178816943 241 Gene3D G3DSA:3.60.40.10 4 240 3.7E-35 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS25575 f7167ddedd707e551743890779cf2084 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 5.6E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS25575 f7167ddedd707e551743890779cf2084 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 5.6E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS25575 f7167ddedd707e551743890779cf2084 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 5.6E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS25575 f7167ddedd707e551743890779cf2084 482 Pfam PF17152 Periplasmic sensor domain 39 139 2.5E-18 T 29-03-2018 IPR033417 Periplasmic sensor domain CHASE8 THSYN_RS25575 f7167ddedd707e551743890779cf2084 482 SUPERFAMILY SSF55874 334 457 3.27E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS25575 f7167ddedd707e551743890779cf2084 482 Gene3D G3DSA:3.30.565.10 222 459 1.9E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS25575 f7167ddedd707e551743890779cf2084 482 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 459 9.2E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS25575 f7167ddedd707e551743890779cf2084 482 SMART SM00304 177 231 0.0089 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS25575 f7167ddedd707e551743890779cf2084 482 Pfam PF07730 Histidine kinase 261 324 6.6E-12 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 THSYN_RS25575 f7167ddedd707e551743890779cf2084 482 SMART SM00387 363 460 1.0E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS25005 62fdefeacb5fc50b60aa87ab998cced3 776 SUPERFAMILY SSF51735 143 330 3.61E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS25005 62fdefeacb5fc50b60aa87ab998cced3 776 Gene3D G3DSA:3.90.180.10 309 366 2.7E-4 T 29-03-2018 THSYN_RS25005 62fdefeacb5fc50b60aa87ab998cced3 776 SMART SM00829 75 361 3.4E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THSYN_RS25005 62fdefeacb5fc50b60aa87ab998cced3 776 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 436 541 6.2E-13 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 THSYN_RS25005 62fdefeacb5fc50b60aa87ab998cced3 776 SUPERFAMILY SSF55347 622 738 2.07E-14 T 29-03-2018 THSYN_RS25005 62fdefeacb5fc50b60aa87ab998cced3 776 SUPERFAMILY SSF51735 436 541 2.25E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS25005 62fdefeacb5fc50b60aa87ab998cced3 776 Gene3D G3DSA:3.90.180.10 1 178 9.2E-28 T 29-03-2018 THSYN_RS25005 62fdefeacb5fc50b60aa87ab998cced3 776 SUPERFAMILY SSF50129 10 55 1.79E-20 T 29-03-2018 IPR011032 GroES-like THSYN_RS25005 62fdefeacb5fc50b60aa87ab998cced3 776 SUPERFAMILY SSF50129 87 176 1.79E-20 T 29-03-2018 IPR011032 GroES-like THSYN_RS25005 62fdefeacb5fc50b60aa87ab998cced3 776 Gene3D G3DSA:3.40.50.720 430 596 5.1E-28 T 29-03-2018 THSYN_RS25005 62fdefeacb5fc50b60aa87ab998cced3 776 Pfam PF00107 Zinc-binding dehydrogenase 178 297 1.9E-19 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THSYN_RS25005 62fdefeacb5fc50b60aa87ab998cced3 776 Gene3D G3DSA:3.40.50.720 179 290 2.4E-21 T 29-03-2018 THSYN_RS25005 62fdefeacb5fc50b60aa87ab998cced3 776 Gene3D G3DSA:3.30.360.10 597 774 2.4E-23 T 29-03-2018 THSYN_RS01480 03783a9e30898789c740b1d8986c507e 436 SUPERFAMILY SSF54631 198 333 4.51E-23 T 29-03-2018 THSYN_RS01480 03783a9e30898789c740b1d8986c507e 436 Gene3D G3DSA:3.20.20.70 168 344 1.4E-21 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS01480 03783a9e30898789c740b1d8986c507e 436 SMART SM01091 344 426 1.1E-28 T 29-03-2018 IPR005170 Transporter-associated domain THSYN_RS01480 03783a9e30898789c740b1d8986c507e 436 Pfam PF03471 Transporter associated domain 346 424 1.7E-22 T 29-03-2018 IPR005170 Transporter-associated domain THSYN_RS01480 03783a9e30898789c740b1d8986c507e 436 SUPERFAMILY SSF56176 345 424 6.27E-22 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THSYN_RS01480 03783a9e30898789c740b1d8986c507e 436 Pfam PF01595 Domain of unknown function DUF21 5 196 9.3E-43 T 29-03-2018 IPR002550 Domain of unknown function DUF21 THSYN_RS01480 03783a9e30898789c740b1d8986c507e 436 Gene3D G3DSA:3.30.465.10 345 435 2.4E-23 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THSYN_RS01480 03783a9e30898789c740b1d8986c507e 436 Pfam PF00571 CBS domain 281 329 5.2E-4 T 29-03-2018 IPR000644 CBS domain THSYN_RS12410 dd62d41f2f7830550f25435016989031 255 SUPERFAMILY SSF55729 18 224 3.81E-39 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS12410 dd62d41f2f7830550f25435016989031 255 Pfam PF13444 Acetyltransferase (GNAT) domain 33 133 1.3E-29 T 29-03-2018 THSYN_RS12410 dd62d41f2f7830550f25435016989031 255 Gene3D G3DSA:3.40.630.30 16 171 1.3E-31 T 29-03-2018 THSYN_RS20510 b785f7e15e371f2bbb5594711f6b62ab 345 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 343 7.9E-154 T 29-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 THSYN_RS20510 b785f7e15e371f2bbb5594711f6b62ab 345 Gene3D G3DSA:3.30.450.90 1 100 2.0E-24 T 29-03-2018 THSYN_RS20510 b785f7e15e371f2bbb5594711f6b62ab 345 Pfam PF00437 Type II/IV secretion system protein 12 264 1.1E-45 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THSYN_RS20510 b785f7e15e371f2bbb5594711f6b62ab 345 SUPERFAMILY SSF52540 5 334 2.76E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS20510 b785f7e15e371f2bbb5594711f6b62ab 345 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THSYN_RS20510 b785f7e15e371f2bbb5594711f6b62ab 345 Gene3D G3DSA:3.40.50.300 273 345 7.5E-14 T 29-03-2018 THSYN_RS20510 b785f7e15e371f2bbb5594711f6b62ab 345 Gene3D G3DSA:3.40.50.300 114 272 3.9E-26 T 29-03-2018 THSYN_RS23520 15b675a9a744499a8cd2db315ae373bb 298 SUPERFAMILY SSF48576 10 290 8.39E-82 T 29-03-2018 IPR008949 Isoprenoid synthase domain THSYN_RS23520 15b675a9a744499a8cd2db315ae373bb 298 Gene3D G3DSA:1.10.600.10 1 297 7.5E-82 T 29-03-2018 IPR008949 Isoprenoid synthase domain THSYN_RS23520 15b675a9a744499a8cd2db315ae373bb 298 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 216 228 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site THSYN_RS23520 15b675a9a744499a8cd2db315ae373bb 298 Pfam PF00348 Polyprenyl synthetase 34 268 3.3E-54 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 THSYN_RS23520 15b675a9a744499a8cd2db315ae373bb 298 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 84 100 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site THSYN_RS00025 16a31dcc9366f253404b06699af9bc97 249 SUPERFAMILY SSF69593 12 230 2.48E-33 T 29-03-2018 THSYN_RS00025 16a31dcc9366f253404b06699af9bc97 249 Pfam PF01553 Acyltransferase 60 184 1.3E-18 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THSYN_RS00025 16a31dcc9366f253404b06699af9bc97 249 SMART SM00563 72 187 5.6E-29 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THSYN_RS00025 16a31dcc9366f253404b06699af9bc97 249 Gene3D G3DSA:3.40.1130.10 32 235 1.5E-32 T 29-03-2018 THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 SUPERFAMILY SSF52540 34 309 5.09E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 580 645 2.5E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 7.0E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 318 4.9E-22 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 578 664 4.2E-24 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 Pfam PF00005 ABC transporter 377 529 4.6E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 Pfam PF00005 ABC transporter 27 183 3.8E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 SUPERFAMILY SSF52540 386 653 8.34E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 SMART SM00382 385 586 1.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 SMART SM00382 34 233 4.9E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 Gene3D G3DSA:3.40.50.300 2 324 7.6E-72 T 29-03-2018 THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 Gene3D G3DSA:3.40.50.300 346 672 4.0E-76 T 29-03-2018 THSYN_RS25660 a8879e942664b0321f67c02c777ac8b5 672 ProSitePatterns PS00211 ABC transporters family signature. 501 515 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS12725 2b9bcd1736171223cdf302edae74e7a3 433 SUPERFAMILY SSF48256 8 432 4.06E-147 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS12725 2b9bcd1736171223cdf302edae74e7a3 433 Gene3D G3DSA:1.10.580.10 56 284 2.3E-72 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain THSYN_RS12725 2b9bcd1736171223cdf302edae74e7a3 433 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 16 426 1.3E-152 T 29-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 THSYN_RS12725 2b9bcd1736171223cdf302edae74e7a3 433 PIRSF PIRSF001369 40 433 2.8E-139 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type THSYN_RS12725 2b9bcd1736171223cdf302edae74e7a3 433 ProSitePatterns PS00480 Citrate synthase signature. 307 319 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 THSYN_RS12725 2b9bcd1736171223cdf302edae74e7a3 433 PRINTS PR00143 Citrate synthase signature 300 320 1.7E-50 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS12725 2b9bcd1736171223cdf302edae74e7a3 433 PRINTS PR00143 Citrate synthase signature 168 181 1.7E-50 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS12725 2b9bcd1736171223cdf302edae74e7a3 433 PRINTS PR00143 Citrate synthase signature 244 272 1.7E-50 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS12725 2b9bcd1736171223cdf302edae74e7a3 433 PRINTS PR00143 Citrate synthase signature 363 379 1.7E-50 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS12725 2b9bcd1736171223cdf302edae74e7a3 433 PRINTS PR00143 Citrate synthase signature 383 397 1.7E-50 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS12725 2b9bcd1736171223cdf302edae74e7a3 433 PRINTS PR00143 Citrate synthase signature 222 237 1.7E-50 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS12725 2b9bcd1736171223cdf302edae74e7a3 433 Pfam PF00285 Citrate synthase, C-terminal domain 49 415 2.6E-127 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS12725 2b9bcd1736171223cdf302edae74e7a3 433 Gene3D G3DSA:1.10.230.10 285 383 9.6E-32 T 29-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain THSYN_RS10675 e41922e01056ef9c3f94190ddc31100c 398 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 1 395 3.1E-191 T 29-03-2018 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 THSYN_RS10675 e41922e01056ef9c3f94190ddc31100c 398 SUPERFAMILY SSF53383 2 397 4.4E-86 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS10675 e41922e01056ef9c3f94190ddc31100c 398 Gene3D G3DSA:3.40.640.10 52 283 7.6E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS10675 e41922e01056ef9c3f94190ddc31100c 398 Pfam PF00155 Aminotransferase class I and II 40 360 1.6E-41 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THSYN_RS10675 e41922e01056ef9c3f94190ddc31100c 398 Gene3D G3DSA:3.90.1150.10 284 398 1.7E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS03555 7d36a95207b29e472ff64d80a5e32a6a 364 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 357 37.894 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THSYN_RS03555 7d36a95207b29e472ff64d80a5e32a6a 364 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 185 348 1.1E-35 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 THSYN_RS03555 7d36a95207b29e472ff64d80a5e32a6a 364 Gene3D G3DSA:3.40.50.2000 175 341 2.4E-27 T 29-03-2018 THSYN_RS03555 7d36a95207b29e472ff64d80a5e32a6a 364 Gene3D G3DSA:3.40.50.2000 3 174 1.2E-43 T 29-03-2018 THSYN_RS03555 7d36a95207b29e472ff64d80a5e32a6a 364 SUPERFAMILY SSF53756 5 357 8.94E-123 T 29-03-2018 THSYN_RS03555 7d36a95207b29e472ff64d80a5e32a6a 364 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 142 7.4E-43 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THSYN_RS03555 7d36a95207b29e472ff64d80a5e32a6a 364 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 4 352 3.5E-111 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THSYN_RS24195 f18a63c12df032937f672e59340b5c9c 108 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 104 2.3E-16 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS24195 f18a63c12df032937f672e59340b5c9c 108 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 108 1.2E-32 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 THSYN_RS24195 f18a63c12df032937f672e59340b5c9c 108 Gene3D G3DSA:2.60.300.12 2 108 4.9E-32 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS24195 f18a63c12df032937f672e59340b5c9c 108 SUPERFAMILY SSF89360 1 97 2.35E-26 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS24195 f18a63c12df032937f672e59340b5c9c 108 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 89 106 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 THSYN_RS30460 0621ce7f8ce30a992b9274d28e2c2e1d 801 SUPERFAMILY SSF52540 98 302 4.16E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30460 0621ce7f8ce30a992b9274d28e2c2e1d 801 SUPERFAMILY SSF52540 351 592 4.16E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30460 0621ce7f8ce30a992b9274d28e2c2e1d 801 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain 147 302 9.8E-9 T 29-03-2018 IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain THSYN_RS30460 0621ce7f8ce30a992b9274d28e2c2e1d 801 Gene3D G3DSA:3.40.50.300 135 601 2.2E-31 T 29-03-2018 THSYN_RS30460 0621ce7f8ce30a992b9274d28e2c2e1d 801 Pfam PF12696 TraM recognition site of TraD and TraG 449 576 1.2E-13 T 29-03-2018 IPR032689 TraD/TraG, TraM recognition site THSYN_RS30460 0621ce7f8ce30a992b9274d28e2c2e1d 801 TIGRFAM TIGR03743 SXT_TraD: conjugative coupling factor TraD, SXT/TOL subfamily 8 597 2.7E-188 T 29-03-2018 IPR022458 Conjugative coupling factor TraG/TraD THSYN_RS01915 54c067cc8cc9be20ad66bbd3475c9c75 116 SMART SM00938 6 104 1.8E-6 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS01915 54c067cc8cc9be20ad66bbd3475c9c75 116 Gene3D G3DSA:3.30.70.120 1 108 1.3E-18 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THSYN_RS01915 54c067cc8cc9be20ad66bbd3475c9c75 116 SUPERFAMILY SSF54913 1 103 4.45E-20 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THSYN_RS27145 b627066b946987b06b902afc12403163 831 Pfam PF00072 Response regulator receiver domain 612 732 3.9E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS27145 b627066b946987b06b902afc12403163 831 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 539 5.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27145 b627066b946987b06b902afc12403163 831 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 563 5.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27145 b627066b946987b06b902afc12403163 831 PRINTS PR00344 Bacterial sensor protein C-terminal signature 569 582 5.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27145 b627066b946987b06b902afc12403163 831 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 525 5.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27145 b627066b946987b06b902afc12403163 831 Gene3D G3DSA:3.40.50.2300 604 756 1.7E-28 T 29-03-2018 THSYN_RS27145 b627066b946987b06b902afc12403163 831 SMART SM00387 474 585 3.2E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27145 b627066b946987b06b902afc12403163 831 SMART SM00388 362 428 2.6E-25 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27145 b627066b946987b06b902afc12403163 831 SMART SM00448 610 732 2.9E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS27145 b627066b946987b06b902afc12403163 831 Gene3D G3DSA:3.30.565.10 423 584 1.6E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27145 b627066b946987b06b902afc12403163 831 SUPERFAMILY SSF47384 349 429 1.73E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27145 b627066b946987b06b902afc12403163 831 Gene3D G3DSA:3.30.450.20 140 365 5.2E-5 T 29-03-2018 THSYN_RS27145 b627066b946987b06b902afc12403163 831 Pfam PF00512 His Kinase A (phospho-acceptor) domain 362 428 3.2E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27145 b627066b946987b06b902afc12403163 831 SUPERFAMILY SSF55874 417 583 4.19E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27145 b627066b946987b06b902afc12403163 831 Gene3D G3DSA:1.10.287.130 366 422 1.2E-22 T 29-03-2018 THSYN_RS27145 b627066b946987b06b902afc12403163 831 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 474 583 1.9E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27145 b627066b946987b06b902afc12403163 831 SUPERFAMILY SSF52172 611 743 4.27E-27 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS30775 4fe7f2acb48dd1ae70244299d254caff 305 Gene3D G3DSA:3.30.460.10 10 136 1.8E-6 T 29-03-2018 THSYN_RS30775 4fe7f2acb48dd1ae70244299d254caff 305 Pfam PF10127 Predicted nucleotidyltransferase 18 266 2.5E-82 T 29-03-2018 IPR018775 Nucleotidyltransferase, predicted THSYN_RS23910 e5fc9453571e6be0bb1b45cb3ea67c6f 203 Pfam PF00573 Ribosomal protein L4/L1 family 14 201 6.1E-65 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 THSYN_RS23910 e5fc9453571e6be0bb1b45cb3ea67c6f 203 Gene3D G3DSA:3.40.1370.10 144 201 3.1E-13 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 THSYN_RS23910 e5fc9453571e6be0bb1b45cb3ea67c6f 203 Gene3D G3DSA:3.40.1370.10 4 143 8.5E-46 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 THSYN_RS23910 e5fc9453571e6be0bb1b45cb3ea67c6f 203 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 14 200 2.3E-73 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23910 e5fc9453571e6be0bb1b45cb3ea67c6f 203 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 6 203 33.917 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23910 e5fc9453571e6be0bb1b45cb3ea67c6f 203 SUPERFAMILY SSF52166 13 202 1.57E-70 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 THSYN_RS25245 7e8369fc86e2ef8faa60a23d8977d56c 185 SUPERFAMILY SSF81593 55 127 1.02E-10 T 29-03-2018 THSYN_RS25245 7e8369fc86e2ef8faa60a23d8977d56c 185 Gene3D G3DSA:1.20.120.330 9 144 3.9E-13 T 29-03-2018 THSYN_RS07120 8d55bea4a952ce862c72c05d54fcddeb 567 Pfam PF16130 Domain of unknown function (DUF4842) 343 552 2.2E-40 T 29-03-2018 IPR032295 Domain of unknown function DUF4842 THSYN_RS07120 8d55bea4a952ce862c72c05d54fcddeb 567 TIGRFAM TIGR04456 LruC_dom: LruC domain 310 553 3.9E-65 T 29-03-2018 IPR031025 LruC domain THSYN_RS07120 8d55bea4a952ce862c72c05d54fcddeb 567 Pfam PF13448 Domain of unknown function (DUF4114) 172 259 4.7E-17 T 29-03-2018 IPR025193 Domain of unknown function DUF4114 THSYN_RS27630 b5d69eeca3e6d60fb60301b3cfff253f 426 Gene3D G3DSA:1.10.1200.70 330 416 6.2E-26 T 29-03-2018 THSYN_RS27630 b5d69eeca3e6d60fb60301b3cfff253f 426 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 416 31.15 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THSYN_RS27630 b5d69eeca3e6d60fb60301b3cfff253f 426 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 154 9.2E-47 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THSYN_RS27630 b5d69eeca3e6d60fb60301b3cfff253f 426 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 170 304 2.6E-48 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase THSYN_RS27630 b5d69eeca3e6d60fb60301b3cfff253f 426 PIRSF PIRSF000445 1 423 1.2E-156 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THSYN_RS27630 b5d69eeca3e6d60fb60301b3cfff253f 426 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 318 415 3.3E-25 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THSYN_RS27630 b5d69eeca3e6d60fb60301b3cfff253f 426 Gene3D G3DSA:3.40.50.720 159 311 3.6E-22 T 29-03-2018 THSYN_RS27630 b5d69eeca3e6d60fb60301b3cfff253f 426 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 97 120 - T 29-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THSYN_RS27630 b5d69eeca3e6d60fb60301b3cfff253f 426 SUPERFAMILY SSF69075 315 416 1.83E-26 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THSYN_RS27630 b5d69eeca3e6d60fb60301b3cfff253f 426 SUPERFAMILY SSF69742 1 156 1.31E-47 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THSYN_RS27630 b5d69eeca3e6d60fb60301b3cfff253f 426 SUPERFAMILY SSF51735 161 313 1.45E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS27630 b5d69eeca3e6d60fb60301b3cfff253f 426 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 415 3.3E-137 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THSYN_RS14155 003dfa4236197e9c6bf5b3717a83492f 565 Gene3D G3DSA:3.40.50.300 346 554 1.6E-37 T 29-03-2018 THSYN_RS14155 003dfa4236197e9c6bf5b3717a83492f 565 Pfam PF06472 ABC transporter transmembrane region 2 2 273 7.3E-57 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS14155 003dfa4236197e9c6bf5b3717a83492f 565 SMART SM00382 375 557 1.1E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS14155 003dfa4236197e9c6bf5b3717a83492f 565 Pfam PF00005 ABC transporter 369 505 9.6E-15 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS14155 003dfa4236197e9c6bf5b3717a83492f 565 Gene3D G3DSA:1.20.1560.10 1 333 1.1E-33 T 29-03-2018 THSYN_RS14155 003dfa4236197e9c6bf5b3717a83492f 565 SUPERFAMILY SSF52540 346 548 2.49E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14155 003dfa4236197e9c6bf5b3717a83492f 565 SUPERFAMILY SSF90123 24 326 3.53E-28 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS15650 e56c0872a705240ab23dab861279fd86 581 SUPERFAMILY SSF51338 538 579 2.07E-25 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS15650 e56c0872a705240ab23dab861279fd86 581 SUPERFAMILY SSF51338 45 109 2.07E-25 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS15650 e56c0872a705240ab23dab861279fd86 581 Gene3D G3DSA:2.30.40.10 524 581 2.4E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS15650 e56c0872a705240ab23dab861279fd86 581 Pfam PF07969 Amidohydrolase family 97 579 6.7E-101 T 29-03-2018 IPR013108 Amidohydrolase 3 THSYN_RS15650 e56c0872a705240ab23dab861279fd86 581 Gene3D G3DSA:2.30.40.10 39 163 3.9E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS15650 e56c0872a705240ab23dab861279fd86 581 Gene3D G3DSA:3.20.20.140 237 523 8.1E-54 T 29-03-2018 THSYN_RS15650 e56c0872a705240ab23dab861279fd86 581 SUPERFAMILY SSF51556 247 539 2.22E-32 T 29-03-2018 IPR032466 Metal-dependent hydrolase THSYN_RS15650 e56c0872a705240ab23dab861279fd86 581 SUPERFAMILY SSF51556 108 140 2.22E-32 T 29-03-2018 IPR032466 Metal-dependent hydrolase THSYN_RS30865 2845d2f79f979ad81937001273c81ffb 286 Gene3D G3DSA:3.90.260.10 171 253 1.3E-5 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS30865 2845d2f79f979ad81937001273c81ffb 286 Pfam PF01841 Transglutaminase-like superfamily 149 236 6.0E-20 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS30865 2845d2f79f979ad81937001273c81ffb 286 SMART SM00460 173 238 2.1E-20 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS30865 2845d2f79f979ad81937001273c81ffb 286 SUPERFAMILY SSF54001 7 265 3.82E-38 T 29-03-2018 THSYN_RS30865 2845d2f79f979ad81937001273c81ffb 286 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 5 81 8.4E-18 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal THSYN_RS28855 342734f9e7fd4dfba7f97c9bf2537ee9 447 Gene3D G3DSA:3.40.50.20 1 123 3.8E-51 T 29-03-2018 THSYN_RS28855 342734f9e7fd4dfba7f97c9bf2537ee9 447 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 1.3E-226 T 29-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 THSYN_RS28855 342734f9e7fd4dfba7f97c9bf2537ee9 447 Gene3D G3DSA:3.30.1490.20 124 211 2.9E-17 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS28855 342734f9e7fd4dfba7f97c9bf2537ee9 447 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 155 169 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THSYN_RS28855 342734f9e7fd4dfba7f97c9bf2537ee9 447 Pfam PF02785 Biotin carboxylase C-terminal domain 337 442 1.2E-36 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THSYN_RS28855 342734f9e7fd4dfba7f97c9bf2537ee9 447 SUPERFAMILY SSF56059 83 344 7.25E-67 T 29-03-2018 THSYN_RS28855 342734f9e7fd4dfba7f97c9bf2537ee9 447 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 9.9E-45 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THSYN_RS28855 342734f9e7fd4dfba7f97c9bf2537ee9 447 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THSYN_RS28855 342734f9e7fd4dfba7f97c9bf2537ee9 447 Gene3D G3DSA:3.30.470.20 212 445 1.5E-97 T 29-03-2018 THSYN_RS28855 342734f9e7fd4dfba7f97c9bf2537ee9 447 SMART SM00878 337 442 1.0E-58 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THSYN_RS28855 342734f9e7fd4dfba7f97c9bf2537ee9 447 SUPERFAMILY SSF51246 332 445 5.76E-40 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THSYN_RS28855 342734f9e7fd4dfba7f97c9bf2537ee9 447 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 1.2E-79 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THSYN_RS28855 342734f9e7fd4dfba7f97c9bf2537ee9 447 SUPERFAMILY SSF52440 1 113 1.73E-47 T 29-03-2018 IPR016185 Pre-ATP-grasp domain THSYN_RS23810 3ec3198eb9f5f714d98058dd70da9ddf 37 SUPERFAMILY SSF57840 1 37 4.05E-17 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23810 3ec3198eb9f5f714d98058dd70da9ddf 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 1.0E-7 T 29-03-2018 THSYN_RS23810 3ec3198eb9f5f714d98058dd70da9ddf 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23810 3ec3198eb9f5f714d98058dd70da9ddf 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 3.5E-22 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23810 3ec3198eb9f5f714d98058dd70da9ddf 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 18.009 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23810 3ec3198eb9f5f714d98058dd70da9ddf 37 Pfam PF00444 Ribosomal protein L36 1 37 9.4E-20 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS32905 6957b08f1b63bc2260f7bf781eef47dd 1083 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 755 1074 2.4E-58 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THSYN_RS32905 6957b08f1b63bc2260f7bf781eef47dd 1083 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 442 645 5.0E-36 T 29-03-2018 IPR000477 Reverse transcriptase domain THSYN_RS32905 6957b08f1b63bc2260f7bf781eef47dd 1083 Gene3D G3DSA:3.30.70.270 481 644 2.5E-30 T 29-03-2018 THSYN_RS32905 6957b08f1b63bc2260f7bf781eef47dd 1083 SUPERFAMILY SSF56672 441 648 4.73E-30 T 29-03-2018 THSYN_RS32905 6957b08f1b63bc2260f7bf781eef47dd 1083 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 487 1064 21.751 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THSYN_RS32905 6957b08f1b63bc2260f7bf781eef47dd 1083 Pfam PF01867 CRISPR associated protein Cas1 756 1036 4.1E-66 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THSYN_RS24035 6e74d87ccf57b824ca7967ab5998f38e 389 SUPERFAMILY SSF52540 16 134 1.92E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24035 6e74d87ccf57b824ca7967ab5998f38e 389 Gene3D G3DSA:3.40.50.300 4 286 2.0E-5 T 29-03-2018 THSYN_RS24035 6e74d87ccf57b824ca7967ab5998f38e 389 Pfam PF13635 Domain of unknown function (DUF4143) 175 334 7.7E-30 T 29-03-2018 IPR025420 Domain of unknown function DUF4143 THSYN_RS24035 6e74d87ccf57b824ca7967ab5998f38e 389 Pfam PF13173 AAA domain 18 133 6.0E-22 T 29-03-2018 THSYN_RS11890 1fda83590b5b5643cf198f07d593eceb 73 Pfam PF00741 Gas vesicle protein 23 61 1.5E-15 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 THSYN_RS24625 30f73c0fd3e6b5d824e06d6f8a54d918 419 Gene3D G3DSA:1.10.645.10 230 410 1.8E-46 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24625 30f73c0fd3e6b5d824e06d6f8a54d918 419 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 419 1.1E-179 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24625 30f73c0fd3e6b5d824e06d6f8a54d918 419 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 29-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24625 30f73c0fd3e6b5d824e06d6f8a54d918 419 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 419 49.797 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24625 30f73c0fd3e6b5d824e06d6f8a54d918 419 Gene3D G3DSA:1.10.645.10 3 229 1.1E-61 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24625 30f73c0fd3e6b5d824e06d6f8a54d918 419 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 419 1.2E-123 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24625 30f73c0fd3e6b5d824e06d6f8a54d918 419 SUPERFAMILY SSF56762 16 167 5.63E-136 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24625 30f73c0fd3e6b5d824e06d6f8a54d918 419 SUPERFAMILY SSF56762 195 419 5.63E-136 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS21245 6cb5d6a3b784b09bfa5855c9c4b24d2e 594 SUPERFAMILY SSF52402 210 361 4.68E-47 T 29-03-2018 THSYN_RS21245 6cb5d6a3b784b09bfa5855c9c4b24d2e 594 SUPERFAMILY SSF52402 438 545 4.68E-47 T 29-03-2018 THSYN_RS21245 6cb5d6a3b784b09bfa5855c9c4b24d2e 594 SUPERFAMILY SSF56235 100 197 5.92E-8 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS21245 6cb5d6a3b784b09bfa5855c9c4b24d2e 594 Pfam PF00733 Asparagine synthase 221 586 2.0E-51 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THSYN_RS21245 6cb5d6a3b784b09bfa5855c9c4b24d2e 594 PIRSF PIRSF001589 99 593 6.6E-54 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS21245 6cb5d6a3b784b09bfa5855c9c4b24d2e 594 Gene3D G3DSA:3.40.50.620 202 593 1.4E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS21245 6cb5d6a3b784b09bfa5855c9c4b24d2e 594 Gene3D G3DSA:3.60.20.10 84 201 2.1E-4 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS31415 457d322b37ceca3bc8c18807b52f7cd8 437 SUPERFAMILY SSF51649 151 431 7.98E-88 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS31415 457d322b37ceca3bc8c18807b52f7cd8 437 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 157 433 8.1E-59 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS31415 457d322b37ceca3bc8c18807b52f7cd8 437 SUPERFAMILY SSF54966 6 149 1.57E-38 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS31415 457d322b37ceca3bc8c18807b52f7cd8 437 Gene3D G3DSA:3.20.20.110 151 434 6.2E-86 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS31415 457d322b37ceca3bc8c18807b52f7cd8 437 Gene3D G3DSA:3.30.70.150 10 149 1.1E-29 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS11815 c6a5b5b315ed4e9bbac8940f78b034f7 566 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 345 542 1.2E-37 T 29-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 THSYN_RS11815 c6a5b5b315ed4e9bbac8940f78b034f7 566 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 375 474 4.1E-7 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THSYN_RS11815 c6a5b5b315ed4e9bbac8940f78b034f7 566 Pfam PF13807 G-rich domain on putative tyrosine kinase 220 293 3.7E-9 T 29-03-2018 IPR032807 Tyrosine kinase, G-rich domain THSYN_RS11815 c6a5b5b315ed4e9bbac8940f78b034f7 566 SUPERFAMILY SSF52540 363 530 6.2E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11815 c6a5b5b315ed4e9bbac8940f78b034f7 566 Gene3D G3DSA:3.30.1890.10 1 267 3.8E-16 T 29-03-2018 THSYN_RS11815 c6a5b5b315ed4e9bbac8940f78b034f7 566 Gene3D G3DSA:3.40.50.300 363 543 7.8E-28 T 29-03-2018 THSYN_RS15015 676f4129c3b1f37a048a0dc3f7750772 405 Gene3D G3DSA:3.40.50.720 1 256 1.7E-48 T 29-03-2018 THSYN_RS15015 676f4129c3b1f37a048a0dc3f7750772 405 SUPERFAMILY SSF51735 9 231 5.12E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS15015 676f4129c3b1f37a048a0dc3f7750772 405 SUPERFAMILY SSF51735 336 395 5.12E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS15015 676f4129c3b1f37a048a0dc3f7750772 405 Pfam PF07994 Myo-inositol-1-phosphate synthase 10 386 2.7E-31 T 29-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 THSYN_RS15015 676f4129c3b1f37a048a0dc3f7750772 405 Gene3D G3DSA:3.40.50.720 257 396 2.8E-26 T 29-03-2018 THSYN_RS15015 676f4129c3b1f37a048a0dc3f7750772 405 SUPERFAMILY SSF55347 232 336 1.44E-30 T 29-03-2018 THSYN_RS15015 676f4129c3b1f37a048a0dc3f7750772 405 PIRSF PIRSF015578 2 401 8.5E-77 T 29-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 THSYN_RS15015 676f4129c3b1f37a048a0dc3f7750772 405 Pfam PF01658 Myo-inositol-1-phosphate synthase 233 337 1.3E-27 T 29-03-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 317 419 6.7E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 202 269 8.1E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 SUPERFAMILY SSF55874 271 420 8.12E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 SUPERFAMILY SSF55785 25 152 9.34E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 SMART SM00086 113 154 0.006 T 29-03-2018 IPR001610 PAC motif THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 105 161 1.2E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 Gene3D G3DSA:3.30.450.20 1 48 2.0E-7 T 29-03-2018 THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 Gene3D G3DSA:3.30.450.20 95 160 1.7E-12 T 29-03-2018 THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 SUPERFAMILY SSF47384 196 270 2.75E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 Gene3D G3DSA:3.30.450.20 161 190 0.22 T 29-03-2018 THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 Pfam PF13426 PAS domain 1 27 0.36 T 29-03-2018 IPR000014 PAS domain THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 Pfam PF13426 PAS domain 99 153 6.3E-4 T 29-03-2018 IPR000014 PAS domain THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 Gene3D G3DSA:3.30.450.20 51 94 6.3E-4 T 29-03-2018 THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 Gene3D G3DSA:1.10.287.130 191 267 1.1E-5 T 29-03-2018 THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 Gene3D G3DSA:3.30.565.10 272 424 4.0E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 SMART SM00387 311 421 2.9E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 399 3.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 418 3.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 380 3.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 366 3.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS17550 28ace481f4ac7823831c9cd53f4d5043 424 SMART SM00388 201 271 2.7E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS09465 d1bb661f367e2fe3719419a4de69a6ea 247 SUPERFAMILY SSF53167 5 244 8.75E-70 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 THSYN_RS09465 d1bb661f367e2fe3719419a4de69a6ea 247 Pfam PF01048 Phosphorylase superfamily 5 244 5.6E-38 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 THSYN_RS09465 d1bb661f367e2fe3719419a4de69a6ea 247 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 3 247 30.811 T 29-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 THSYN_RS09465 d1bb661f367e2fe3719419a4de69a6ea 247 Gene3D G3DSA:3.40.50.1580 4 246 6.1E-34 T 29-03-2018 THSYN_RS12000 32110bd2094bb82bc798ad704bb4693b 81 SUPERFAMILY SSF46689 3 71 5.2E-21 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS12000 32110bd2094bb82bc798ad704bb4693b 81 Pfam PF04255 Protein of unknown function (DUF433) 10 65 8.9E-23 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS12000 32110bd2094bb82bc798ad704bb4693b 81 Gene3D G3DSA:1.10.10.10 10 72 4.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS09025 3fbfdb943db89ad4f3ecd3703510b252 349 Pfam PF00072 Response regulator receiver domain 109 167 1.0E-7 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS09025 3fbfdb943db89ad4f3ecd3703510b252 349 Gene3D G3DSA:3.40.50.2300 17 203 2.7E-15 T 29-03-2018 THSYN_RS09025 3fbfdb943db89ad4f3ecd3703510b252 349 SUPERFAMILY SSF52172 113 188 9.11E-11 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 PIRSF PIRSF000310 5 353 1.1E-129 T 29-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 Gene3D G3DSA:3.40.50.700 45 232 2.2E-44 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 SUPERFAMILY SSF56770 47 307 3.92E-84 T 29-03-2018 THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 62 205 3.9E-31 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 225 304 8.9E-32 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 254 280 6.2E-71 T 29-03-2018 THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 230 248 6.2E-71 T 29-03-2018 THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 282 295 6.2E-71 T 29-03-2018 THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 157 181 6.2E-71 T 29-03-2018 THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 47 69 6.2E-71 T 29-03-2018 THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 70 94 6.2E-71 T 29-03-2018 THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 212 229 6.2E-71 T 29-03-2018 THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 186 209 6.2E-71 T 29-03-2018 THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 16 34 5.4E-4 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 Gene3D G3DSA:4.10.480.10 233 307 4.3E-34 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THSYN_RS19030 894091876c5f0ded140864a7d1239e11 354 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 4 335 4.7E-124 T 29-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THSYN_RS11420 36044a37ecd0061c41bc2407663d5c71 80 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 51 5.8E-7 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS11420 36044a37ecd0061c41bc2407663d5c71 80 SMART SM00966 10 50 0.0033 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS11420 36044a37ecd0061c41bc2407663d5c71 80 Gene3D G3DSA:2.10.260.10 1 71 1.2E-5 T 29-03-2018 THSYN_RS11420 36044a37ecd0061c41bc2407663d5c71 80 SUPERFAMILY SSF89447 6 70 7.32E-9 T 29-03-2018 THSYN_RS26760 e8727d8360379cb553e8eb450b2ef2a7 397 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 4 395 2.1E-228 T 29-03-2018 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 THSYN_RS26760 e8727d8360379cb553e8eb450b2ef2a7 397 Pfam PF04303 PrpF protein 6 392 1.4E-176 T 29-03-2018 IPR007400 PrpF protein THSYN_RS26760 e8727d8360379cb553e8eb450b2ef2a7 397 Gene3D G3DSA:3.10.310.10 202 374 1.1E-70 T 29-03-2018 THSYN_RS26760 e8727d8360379cb553e8eb450b2ef2a7 397 Gene3D G3DSA:3.10.310.10 5 201 1.6E-85 T 29-03-2018 THSYN_RS26760 e8727d8360379cb553e8eb450b2ef2a7 397 SUPERFAMILY SSF54506 190 394 7.32E-77 T 29-03-2018 THSYN_RS26760 e8727d8360379cb553e8eb450b2ef2a7 397 SUPERFAMILY SSF54506 2 182 2.59E-71 T 29-03-2018 THSYN_RS02720 d4ebfb067a68dd12430560169038a4f0 140 SMART SM00507 8 63 0.0027 T 29-03-2018 IPR003615 HNH nuclease THSYN_RS02720 d4ebfb067a68dd12430560169038a4f0 140 Gene3D G3DSA:3.40.1800.10 1 76 6.9E-18 T 29-03-2018 THSYN_RS02720 d4ebfb067a68dd12430560169038a4f0 140 Pfam PF14279 HNH endonuclease 21 71 5.9E-12 T 29-03-2018 IPR029471 HNH endonuclease 5 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 Pfam PF00873 AcrB/AcrD/AcrF family 17 1041 1.5E-161 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 Gene3D G3DSA:3.30.70.1430 590 697 1.0E-10 T 29-03-2018 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 SUPERFAMILY SSF82714 197 277 1.03E-10 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 Gene3D G3DSA:3.30.2090.10 740 828 2.3E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 SUPERFAMILY SSF82714 742 826 2.62E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 Gene3D G3DSA:1.20.1640.10 294 514 1.8E-30 T 29-03-2018 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 Gene3D G3DSA:3.30.2090.10 193 279 4.5E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 SUPERFAMILY SSF82693 592 675 1.36E-5 T 29-03-2018 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 SUPERFAMILY SSF82693 53 148 3.92E-17 T 29-03-2018 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 SUPERFAMILY SSF82866 309 500 7.98E-35 T 29-03-2018 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 Gene3D G3DSA:1.20.1640.10 847 1046 9.4E-34 T 29-03-2018 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 Gene3D G3DSA:3.30.70.1430 53 156 3.6E-28 T 29-03-2018 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 SUPERFAMILY SSF82693 280 330 5.07E-16 T 29-03-2018 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 SUPERFAMILY SSF82693 149 194 5.07E-16 T 29-03-2018 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 PRINTS PR00702 Acriflavin resistance protein family signature 342 365 1.3E-21 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 PRINTS PR00702 Acriflavin resistance protein family signature 474 497 1.3E-21 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 PRINTS PR00702 Acriflavin resistance protein family signature 396 420 1.3E-21 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 PRINTS PR00702 Acriflavin resistance protein family signature 51 69 1.3E-21 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 PRINTS PR00702 Acriflavin resistance protein family signature 449 472 1.3E-21 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS28230 72f051a730cd4e87bac413416c3c4e2b 1056 SUPERFAMILY SSF82866 825 1046 2.22E-46 T 29-03-2018 THSYN_RS07270 4d038835e1f6d7b8045ba807ea8443b2 281 SUPERFAMILY SSF52980 28 210 1.02E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS07270 4d038835e1f6d7b8045ba807ea8443b2 281 Gene3D G3DSA:3.90.1570.10 26 210 1.2E-22 T 29-03-2018 THSYN_RS07270 4d038835e1f6d7b8045ba807ea8443b2 281 Pfam PF05685 Putative restriction endonuclease 36 207 5.3E-17 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS29260 5b705cb9245d829c012c171634c0700f 309 Gene3D G3DSA:3.40.50.300 20 185 7.5E-25 T 29-03-2018 THSYN_RS29260 5b705cb9245d829c012c171634c0700f 309 PIRSF PIRSF002849 4 309 2.4E-113 T 29-03-2018 THSYN_RS29260 5b705cb9245d829c012c171634c0700f 309 SUPERFAMILY SSF52540 26 282 4.45E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29260 5b705cb9245d829c012c171634c0700f 309 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 39 169 1.1E-62 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 THSYN_RS29260 5b705cb9245d829c012c171634c0700f 309 SMART SM00382 36 177 6.8E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS29260 5b705cb9245d829c012c171634c0700f 309 Gene3D G3DSA:1.10.8.300 200 306 2.5E-21 T 29-03-2018 THSYN_RS09040 a55565dddff2ea14db0a540f866c8a3f 572 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 43 567 2.4E-141 T 29-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 THSYN_RS09040 a55565dddff2ea14db0a540f866c8a3f 572 Pfam PF02272 DHHA1 domain 319 450 1.2E-17 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 THSYN_RS09040 a55565dddff2ea14db0a540f866c8a3f 572 Pfam PF01368 DHH family 72 199 6.6E-8 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 THSYN_RS09040 a55565dddff2ea14db0a540f866c8a3f 572 SUPERFAMILY SSF64182 47 462 4.58E-111 T 29-03-2018 THSYN_RS09040 a55565dddff2ea14db0a540f866c8a3f 572 Gene3D G3DSA:3.90.1640.10 49 243 6.4E-17 T 29-03-2018 THSYN_RS07240 66cd5b62a782984e6e74b562e86efe54 243 Pfam PF13578 Methyltransferase domain 82 197 3.9E-9 T 29-03-2018 THSYN_RS07240 66cd5b62a782984e6e74b562e86efe54 243 Gene3D G3DSA:3.40.50.150 56 225 2.4E-23 T 29-03-2018 THSYN_RS07240 66cd5b62a782984e6e74b562e86efe54 243 SUPERFAMILY SSF53335 66 204 1.13E-13 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS29130 05adc157dfea98f501857b0e4274c2a0 73 Gene3D G3DSA:1.10.260.40 1 71 2.2E-20 T 29-03-2018 THSYN_RS29130 05adc157dfea98f501857b0e4274c2a0 73 SMART SM00530 13 68 1.1E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS29130 05adc157dfea98f501857b0e4274c2a0 73 SUPERFAMILY SSF47413 8 71 2.68E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS29130 05adc157dfea98f501857b0e4274c2a0 73 Pfam PF01381 Helix-turn-helix 14 68 2.1E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS31195 4b80b7e0683b3beb3215fa0b9f8fcf98 338 SUPERFAMILY SSF109709 155 236 9.68E-15 T 29-03-2018 THSYN_RS31195 4b80b7e0683b3beb3215fa0b9f8fcf98 338 Gene3D G3DSA:3.90.1530.10 55 163 1.2E-11 T 29-03-2018 THSYN_RS31195 4b80b7e0683b3beb3215fa0b9f8fcf98 338 Pfam PF02195 ParB-like nuclease domain 69 161 5.4E-11 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS31195 4b80b7e0683b3beb3215fa0b9f8fcf98 338 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 66 231 1.5E-25 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 THSYN_RS31195 4b80b7e0683b3beb3215fa0b9f8fcf98 338 SMART SM00470 67 162 5.3E-10 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS31195 4b80b7e0683b3beb3215fa0b9f8fcf98 338 SUPERFAMILY SSF110849 69 164 7.32E-10 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS31195 4b80b7e0683b3beb3215fa0b9f8fcf98 338 Gene3D G3DSA:1.10.10.730 164 211 5.0E-9 T 29-03-2018 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Gene3D G3DSA:3.40.50.1460 814 1063 6.9E-24 T 29-03-2018 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Gene3D G3DSA:1.10.150.200 180 225 1.5E-8 T 29-03-2018 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Gene3D G3DSA:1.10.150.160 351 370 0.056 T 29-03-2018 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Gene3D G3DSA:1.20.1250.10 226 286 2.6E-19 T 29-03-2018 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 PRINTS PR00381 Kinesin light chain signature 214 233 6.3E-12 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 PRINTS PR00381 Kinesin light chain signature 236 254 6.3E-12 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 PRINTS PR00381 Kinesin light chain signature 345 365 6.3E-12 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 PRINTS PR00381 Kinesin light chain signature 301 318 6.3E-12 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 PRINTS PR00381 Kinesin light chain signature 380 401 6.3E-12 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 SUPERFAMILY SSF48452 93 450 2.18E-27 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Pfam PF13424 Tetratricopeptide repeat 185 252 2.5E-15 T 29-03-2018 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Pfam PF13424 Tetratricopeptide repeat 265 336 1.0E-18 T 29-03-2018 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Pfam PF13424 Tetratricopeptide repeat 99 158 5.0E-17 T 29-03-2018 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Pfam PF13424 Tetratricopeptide repeat 346 418 1.7E-16 T 29-03-2018 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 SMART SM00028 263 296 10.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 SMART SM00028 137 170 180.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 SMART SM00028 221 254 50.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 SMART SM00028 347 380 23.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 SMART SM00028 95 128 6.6 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 SMART SM00028 389 422 39.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 SMART SM00028 53 86 370.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 SMART SM00028 305 338 8.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Gene3D G3DSA:1.10.10.10 371 450 6.9E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Gene3D G3DSA:1.10.10.10 123 179 1.6E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Gene3D G3DSA:1.10.10.10 64 122 3.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Gene3D G3DSA:1.10.10.10 287 350 3.8E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Gene3D G3DSA:3.30.429.10 19 55 0.037 T 29-03-2018 THSYN_RS21855 2c0b3d353950a5be6a2c21a73958bf86 1066 Pfam PF12770 CHAT domain 735 1063 6.4E-58 T 29-03-2018 IPR024983 CHAT domain THSYN_RS00435 4095407ae5d5e2fef8313f074ff95ebd 396 SMART SM00079 51 270 8.2E-4 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 THSYN_RS00435 4095407ae5d5e2fef8313f074ff95ebd 396 SUPERFAMILY SSF54106 286 336 4.58E-5 T 29-03-2018 IPR018392 LysM domain THSYN_RS00435 4095407ae5d5e2fef8313f074ff95ebd 396 Gene3D G3DSA:3.40.190.10 41 153 7.4E-30 T 29-03-2018 THSYN_RS00435 4095407ae5d5e2fef8313f074ff95ebd 396 Pfam PF01476 LysM domain 288 336 2.1E-8 T 29-03-2018 IPR018392 LysM domain THSYN_RS00435 4095407ae5d5e2fef8313f074ff95ebd 396 SMART SM00062 51 272 7.7E-60 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS00435 4095407ae5d5e2fef8313f074ff95ebd 396 SMART SM00257 287 336 1.5E-4 T 29-03-2018 IPR018392 LysM domain THSYN_RS00435 4095407ae5d5e2fef8313f074ff95ebd 396 Gene3D G3DSA:3.40.190.10 154 226 1.3E-17 T 29-03-2018 THSYN_RS00435 4095407ae5d5e2fef8313f074ff95ebd 396 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 52 268 1.3E-56 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS00435 4095407ae5d5e2fef8313f074ff95ebd 396 Gene3D G3DSA:3.10.350.10 284 337 1.4E-11 T 29-03-2018 THSYN_RS00435 4095407ae5d5e2fef8313f074ff95ebd 396 SUPERFAMILY SSF53850 23 271 1.75E-63 T 29-03-2018 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 Gene3D G3DSA:1.10.274.10 202 307 2.5E-25 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 Pfam PF05524 PEP-utilising enzyme, N-terminal 178 299 1.1E-21 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 618 633 1.5E-22 T 29-03-2018 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 635 650 1.5E-22 T 29-03-2018 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 465 484 1.5E-22 T 29-03-2018 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 671 683 1.5E-22 T 29-03-2018 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 SUPERFAMILY SSF51621 426 711 1.96E-100 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 Pfam PF00391 PEP-utilising enzyme, mobile domain 325 397 1.3E-14 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 SUPERFAMILY SSF55781 2 162 6.32E-31 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 424 711 3.9E-99 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 178 733 3.7E-127 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 SUPERFAMILY SSF47831 203 316 1.01E-25 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 Gene3D G3DSA:3.30.450.40 1 166 5.1E-31 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 Pfam PF01590 GAF domain 17 154 5.2E-19 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 Gene3D G3DSA:3.50.30.10 308 426 9.2E-19 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 SMART SM00065 17 164 3.4E-25 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 Gene3D G3DSA:3.20.20.60 427 744 7.9E-93 T 29-03-2018 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 SUPERFAMILY SSF52009 298 415 6.93E-25 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THSYN_RS28915 94395c5f3715dec2dd9f6112e1da8525 753 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 618 636 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 THSYN_RS05480 bd14531123ee13baac03aa404f7f48ee 873 SUPERFAMILY SSF52540 459 773 1.7E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05480 bd14531123ee13baac03aa404f7f48ee 873 Pfam PF01580 FtsK/SpoIIIE family 486 701 2.6E-65 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 THSYN_RS05480 bd14531123ee13baac03aa404f7f48ee 873 Pfam PF09397 Ftsk gamma domain 807 867 2.8E-27 T 29-03-2018 IPR018541 FtsK gamma domain THSYN_RS05480 bd14531123ee13baac03aa404f7f48ee 873 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 17 191 3.1E-38 T 29-03-2018 IPR025199 DNA translocase FtsK, 4TM region THSYN_RS05480 bd14531123ee13baac03aa404f7f48ee 873 SUPERFAMILY SSF46785 806 870 9.52E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS05480 bd14531123ee13baac03aa404f7f48ee 873 Gene3D G3DSA:3.40.50.300 390 741 5.9E-55 T 29-03-2018 THSYN_RS05480 bd14531123ee13baac03aa404f7f48ee 873 Gene3D G3DSA:1.10.10.10 807 861 1.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS05480 bd14531123ee13baac03aa404f7f48ee 873 SMART SM00843 805 870 6.4E-38 T 29-03-2018 IPR018541 FtsK gamma domain THSYN_RS05480 bd14531123ee13baac03aa404f7f48ee 873 SMART SM00382 521 722 0.0035 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 PRINTS PR00097 Anthranilate synthase component II signature 347 360 1.9E-5 T 29-03-2018 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 PRINTS PR00097 Anthranilate synthase component II signature 234 243 1.9E-5 T 29-03-2018 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 PRINTS PR00097 Anthranilate synthase component II signature 262 273 1.9E-5 T 29-03-2018 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 373 5.2E-141 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 132 3.9E-50 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 376 48.048 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 231 245 2.4E-39 T 29-03-2018 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 304 315 2.4E-39 T 29-03-2018 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 192 206 2.4E-39 T 29-03-2018 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 262 278 2.4E-39 T 29-03-2018 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 279 296 2.4E-39 T 29-03-2018 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 SUPERFAMILY SSF52317 181 374 2.87E-59 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 Gene3D G3DSA:3.50.30.20 2 151 3.2E-60 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 SUPERFAMILY SSF52021 4 142 7.59E-56 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 SMART SM01097 3 133 9.4E-90 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 Gene3D G3DSA:3.40.50.880 152 377 3.4E-63 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 PRINTS PR00096 Glutamine amidotransferase superfamily signature 262 273 5.5E-11 T 29-03-2018 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 PRINTS PR00096 Glutamine amidotransferase superfamily signature 234 243 5.5E-11 T 29-03-2018 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 PRINTS PR00096 Glutamine amidotransferase superfamily signature 347 360 5.5E-11 T 29-03-2018 THSYN_RS22435 b09211bb0edaa362e3e10ae8afa70750 377 Pfam PF00117 Glutamine amidotransferase class-I 196 370 1.1E-46 T 29-03-2018 IPR017926 Glutamine amidotransferase THSYN_RS13610 d856b669f53d401dab0bc6c3c4b18e7e 146 Pfam PF01850 PIN domain 8 121 4.0E-7 T 29-03-2018 IPR002716 PIN domain THSYN_RS13610 d856b669f53d401dab0bc6c3c4b18e7e 146 SUPERFAMILY SSF88723 7 134 1.21E-16 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS13610 d856b669f53d401dab0bc6c3c4b18e7e 146 Gene3D G3DSA:3.40.50.1010 2 139 7.9E-16 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS07110 b16e593caaa0a9bb61ee3e56bd01e5eb 623 Pfam PF03734 L,D-transpeptidase catalytic domain 320 470 1.0E-24 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 THSYN_RS07110 b16e593caaa0a9bb61ee3e56bd01e5eb 623 Pfam PF01471 Putative peptidoglycan binding domain 233 291 5.0E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS07110 b16e593caaa0a9bb61ee3e56bd01e5eb 623 SUPERFAMILY SSF47090 220 294 2.41E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS07110 b16e593caaa0a9bb61ee3e56bd01e5eb 623 Gene3D G3DSA:2.40.440.10 319 474 4.9E-23 T 29-03-2018 THSYN_RS07110 b16e593caaa0a9bb61ee3e56bd01e5eb 623 SUPERFAMILY SSF141523 412 462 2.88E-19 T 29-03-2018 THSYN_RS07110 b16e593caaa0a9bb61ee3e56bd01e5eb 623 SUPERFAMILY SSF141523 318 373 2.88E-19 T 29-03-2018 THSYN_RS07110 b16e593caaa0a9bb61ee3e56bd01e5eb 623 Gene3D G3DSA:1.10.101.10 222 296 2.1E-14 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS32415 fda9fe2caf30204640bbc7a8878da768 209 Gene3D G3DSA:3.40.50.1390 54 191 2.1E-24 T 29-03-2018 THSYN_RS32415 fda9fe2caf30204640bbc7a8878da768 209 SUPERFAMILY SSF46955 4 50 5.04E-11 T 29-03-2018 IPR009061 Putative DNA-binding domain THSYN_RS32415 fda9fe2caf30204640bbc7a8878da768 209 Gene3D G3DSA:1.10.1660.10 1 52 3.9E-15 T 29-03-2018 THSYN_RS32415 fda9fe2caf30204640bbc7a8878da768 209 SMART SM00422 5 78 0.0056 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THSYN_RS32415 fda9fe2caf30204640bbc7a8878da768 209 SUPERFAMILY SSF53041 59 188 4.45E-20 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THSYN_RS32415 fda9fe2caf30204640bbc7a8878da768 209 Pfam PF13411 MerR HTH family regulatory protein 5 50 5.7E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THSYN_RS32415 fda9fe2caf30204640bbc7a8878da768 209 Pfam PF00239 Resolvase, N terminal domain 60 186 1.6E-17 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THSYN_RS32415 fda9fe2caf30204640bbc7a8878da768 209 SMART SM00857 60 189 1.1E-17 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THSYN_RS30680 fda9fe2caf30204640bbc7a8878da768 209 Gene3D G3DSA:3.40.50.1390 54 191 2.1E-24 T 29-03-2018 THSYN_RS30680 fda9fe2caf30204640bbc7a8878da768 209 SUPERFAMILY SSF46955 4 50 5.04E-11 T 29-03-2018 IPR009061 Putative DNA-binding domain THSYN_RS30680 fda9fe2caf30204640bbc7a8878da768 209 Gene3D G3DSA:1.10.1660.10 1 52 3.9E-15 T 29-03-2018 THSYN_RS30680 fda9fe2caf30204640bbc7a8878da768 209 SMART SM00422 5 78 0.0056 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THSYN_RS30680 fda9fe2caf30204640bbc7a8878da768 209 SUPERFAMILY SSF53041 59 188 4.45E-20 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THSYN_RS30680 fda9fe2caf30204640bbc7a8878da768 209 Pfam PF13411 MerR HTH family regulatory protein 5 50 5.7E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THSYN_RS30680 fda9fe2caf30204640bbc7a8878da768 209 Pfam PF00239 Resolvase, N terminal domain 60 186 1.6E-17 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THSYN_RS30680 fda9fe2caf30204640bbc7a8878da768 209 SMART SM00857 60 189 1.1E-17 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THSYN_RS13760 83ede978cc74b12eabfdbfaa3627e617 168 SUPERFAMILY SSF56436 2 156 8.48E-36 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS13760 83ede978cc74b12eabfdbfaa3627e617 168 Pfam PF03781 Sulfatase-modifying factor enzyme 1 2 153 3.2E-27 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS13760 83ede978cc74b12eabfdbfaa3627e617 168 Gene3D G3DSA:3.90.1580.10 1 162 2.1E-34 T 29-03-2018 THSYN_RS06805 09eb9b7663a212146e370fe1d4674686 580 Pfam PF00664 ABC transporter transmembrane region 55 314 4.2E-15 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS06805 09eb9b7663a212146e370fe1d4674686 580 Gene3D G3DSA:3.40.50.300 348 577 2.0E-58 T 29-03-2018 THSYN_RS06805 09eb9b7663a212146e370fe1d4674686 580 Pfam PF00005 ABC transporter 374 523 2.8E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS06805 09eb9b7663a212146e370fe1d4674686 580 SUPERFAMILY SSF52540 352 572 2.47E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06805 09eb9b7663a212146e370fe1d4674686 580 SUPERFAMILY SSF90123 33 325 4.32E-37 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS06805 09eb9b7663a212146e370fe1d4674686 580 SUPERFAMILY SSF90123 499 507 4.32E-37 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS06805 09eb9b7663a212146e370fe1d4674686 580 SMART SM00382 383 575 1.9E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS06805 09eb9b7663a212146e370fe1d4674686 580 Gene3D G3DSA:1.20.1560.10 17 341 9.1E-25 T 29-03-2018 THSYN_RS06805 09eb9b7663a212146e370fe1d4674686 580 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS20010 3d8adcbde5b25e57c3fc8491e7337ddd 208 SUPERFAMILY SSF69118 11 95 1.32E-11 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 THSYN_RS20010 3d8adcbde5b25e57c3fc8491e7337ddd 208 Pfam PF02627 Carboxymuconolactone decarboxylase family 23 92 1.8E-6 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THSYN_RS20010 3d8adcbde5b25e57c3fc8491e7337ddd 208 SUPERFAMILY SSF50022 110 206 1.2E-20 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THSYN_RS20010 3d8adcbde5b25e57c3fc8491e7337ddd 208 Gene3D G3DSA:1.20.1290.10 2 94 8.6E-8 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 THSYN_RS20010 3d8adcbde5b25e57c3fc8491e7337ddd 208 Gene3D G3DSA:2.102.10.10 110 207 7.5E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THSYN_RS20010 3d8adcbde5b25e57c3fc8491e7337ddd 208 Pfam PF00355 Rieske [2Fe-2S] domain 110 187 3.0E-12 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THSYN_RS23480 9f543ada0a36b7421abbe6a88444b1f5 317 SUPERFAMILY SSF52980 26 210 1.23E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS23480 9f543ada0a36b7421abbe6a88444b1f5 317 Pfam PF05685 Putative restriction endonuclease 37 207 2.4E-15 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS23480 9f543ada0a36b7421abbe6a88444b1f5 317 Gene3D G3DSA:3.90.1570.10 23 213 2.4E-21 T 29-03-2018 THSYN_RS08365 70040937bff91688db17b9e432d25838 192 Gene3D G3DSA:1.10.10.10 116 189 1.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS08365 70040937bff91688db17b9e432d25838 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 186 1.7E-34 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08365 70040937bff91688db17b9e432d25838 192 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 2 190 4.2E-97 T 29-03-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08365 70040937bff91688db17b9e432d25838 192 SUPERFAMILY SSF88659 123 186 1.36E-18 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08365 70040937bff91688db17b9e432d25838 192 SUPERFAMILY SSF88946 7 107 8.01E-30 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08365 70040937bff91688db17b9e432d25838 192 Pfam PF04542 Sigma-70 region 2 25 92 1.3E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08365 70040937bff91688db17b9e432d25838 192 Gene3D G3DSA:1.10.1740.10 2 115 2.0E-29 T 29-03-2018 THSYN_RS08365 70040937bff91688db17b9e432d25838 192 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 78 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08365 70040937bff91688db17b9e432d25838 192 Pfam PF08281 Sigma-70, region 4 132 181 9.9E-19 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS11760 956925e85370dc802100c2ff07ff2922 157 Pfam PF04386 Stringent starvation protein B 10 157 8.7E-36 T 29-03-2018 IPR007481 Stringent starvation protein B THSYN_RS11760 956925e85370dc802100c2ff07ff2922 157 SUPERFAMILY SSF101738 7 114 2.62E-45 T 29-03-2018 IPR007481 Stringent starvation protein B THSYN_RS11760 956925e85370dc802100c2ff07ff2922 157 PIRSF PIRSF005276 6 157 4.4E-51 T 29-03-2018 IPR007481 Stringent starvation protein B THSYN_RS11760 956925e85370dc802100c2ff07ff2922 157 Gene3D G3DSA:2.30.30.220 12 109 1.4E-38 T 29-03-2018 IPR007481 Stringent starvation protein B THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SUPERFAMILY SSF48371 4 175 1.22E-16 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 Pfam PF03130 PBS lyase HEAT-like repeat 127 149 0.0022 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 Pfam PF03130 PBS lyase HEAT-like repeat 480 500 0.015 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SUPERFAMILY SSF48371 261 467 2.3E-36 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 Pfam PF13646 HEAT repeats 506 600 2.5E-10 T 29-03-2018 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 Pfam PF13646 HEAT repeats 57 120 1.4E-9 T 29-03-2018 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 Pfam PF13646 HEAT repeats 343 427 4.8E-17 T 29-03-2018 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 Pfam PF13646 HEAT repeats 260 331 6.2E-12 T 29-03-2018 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SMART SM00567 E-Z type HEAT repeats 505 534 0.15 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SMART SM00567 E-Z type HEAT repeats 474 503 46.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SMART SM00567 E-Z type HEAT repeats 261 290 0.066 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SMART SM00567 E-Z type HEAT repeats 123 152 1.5 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SMART SM00567 E-Z type HEAT repeats 355 384 0.025 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SMART SM00567 E-Z type HEAT repeats 292 321 0.0019 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SMART SM00567 E-Z type HEAT repeats 536 587 99.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SMART SM00567 E-Z type HEAT repeats 386 415 1.1E-4 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SMART SM00567 E-Z type HEAT repeats 93 122 7.1E-6 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SMART SM00567 E-Z type HEAT repeats 324 353 29.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SMART SM00567 E-Z type HEAT repeats 60 89 0.1 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SMART SM00567 E-Z type HEAT repeats 417 468 250.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 Gene3D G3DSA:1.25.40.70 24 108 6.7E-10 T 29-03-2018 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 Gene3D G3DSA:1.25.40.70 401 473 2.6E-5 T 29-03-2018 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 Gene3D G3DSA:1.25.40.70 474 551 1.3E-11 T 29-03-2018 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 Gene3D G3DSA:1.25.40.70 228 338 6.9E-16 T 29-03-2018 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 Gene3D G3DSA:1.25.40.70 109 169 1.6E-5 T 29-03-2018 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 Gene3D G3DSA:1.25.40.70 565 604 0.034 T 29-03-2018 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 Gene3D G3DSA:1.25.40.70 339 400 9.0E-12 T 29-03-2018 THSYN_RS12040 409aa1a37a60feefc46834d374aaedaf 662 SUPERFAMILY SSF48371 374 614 1.26E-18 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS29395 5df7c68763fe4d631e619d250c938f38 242 Gene3D G3DSA:3.40.30.10 1 91 4.7E-9 T 29-03-2018 THSYN_RS29395 5df7c68763fe4d631e619d250c938f38 242 SUPERFAMILY SSF47616 141 226 6.82E-7 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like THSYN_RS29395 5df7c68763fe4d631e619d250c938f38 242 Pfam PF17172 Glutathione S-transferase N-terminal domain 18 112 7.1E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS29395 5df7c68763fe4d631e619d250c938f38 242 Pfam PF17171 Glutathione S-transferase, C-terminal domain 164 224 2.3E-11 T 29-03-2018 IPR033468 Metaxin, glutathione S-transferase domain THSYN_RS29395 5df7c68763fe4d631e619d250c938f38 242 Gene3D G3DSA:1.20.1050.10 92 226 3.0E-9 T 29-03-2018 THSYN_RS29395 5df7c68763fe4d631e619d250c938f38 242 SUPERFAMILY SSF52833 1 99 6.77E-9 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS30580 7b49d4f725fcfba382b4f6cd19f9f567 134 Gene3D G3DSA:3.30.479.10 1 132 1.7E-26 T 29-03-2018 THSYN_RS30580 7b49d4f725fcfba382b4f6cd19f9f567 134 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 6 130 1.4E-20 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 THSYN_RS30580 7b49d4f725fcfba382b4f6cd19f9f567 134 SUPERFAMILY SSF55620 1 129 2.72E-27 T 29-03-2018 THSYN_RS03575 3455ae6cd4e64585bf990ff41341b168 304 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 1 207 20.05 T 29-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 THSYN_RS03575 3455ae6cd4e64585bf990ff41341b168 304 Pfam PF03799 Cell division protein FtsQ 89 199 2.0E-17 T 29-03-2018 IPR005548 Cell division protein FtsQ/DivIB THSYN_RS03575 3455ae6cd4e64585bf990ff41341b168 304 Pfam PF08478 POTRA domain, FtsQ-type 16 85 4.5E-15 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type THSYN_RS30020 09e9a1f4676e8fbdf0d3bb617ce332d1 109 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 30.829 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 THSYN_RS30020 09e9a1f4676e8fbdf0d3bb617ce332d1 109 SMART SM00411 3 92 9.4E-43 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS30020 09e9a1f4676e8fbdf0d3bb617ce332d1 109 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 6.7E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS30020 09e9a1f4676e8fbdf0d3bb617ce332d1 109 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 6.7E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS30020 09e9a1f4676e8fbdf0d3bb617ce332d1 109 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 6.7E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS30020 09e9a1f4676e8fbdf0d3bb617ce332d1 109 SUPERFAMILY SSF47729 3 92 5.45E-32 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS30020 09e9a1f4676e8fbdf0d3bb617ce332d1 109 Pfam PF00216 Bacterial DNA-binding protein 3 91 2.3E-32 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS30020 09e9a1f4676e8fbdf0d3bb617ce332d1 109 Gene3D G3DSA:4.10.520.10 1 97 5.9E-33 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS30020 09e9a1f4676e8fbdf0d3bb617ce332d1 109 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 THSYN_RS30020 09e9a1f4676e8fbdf0d3bb617ce332d1 109 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 96 5.0E-47 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Gene3D G3DSA:1.25.40.10 140 208 2.3E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Gene3D G3DSA:1.25.40.10 248 313 8.6E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Gene3D G3DSA:1.25.40.10 669 746 3.0E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Gene3D G3DSA:1.25.40.10 747 819 2.1E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Pfam PF14559 Tetratricopeptide repeat 519 574 1.1E-5 T 29-03-2018 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Pfam PF14559 Tetratricopeptide repeat 351 411 3.4E-10 T 29-03-2018 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Gene3D G3DSA:1.25.40.10 314 372 2.5E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Gene3D G3DSA:1.25.40.10 433 523 1.2E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 237 270 360.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 474 507 0.0092 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 271 304 53.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 712 745 54.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 847 880 6.8 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 881 914 18.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 373 406 54.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 203 236 0.17 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 25 58 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 339 372 0.47 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 644 677 0.014 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 813 846 0.87 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 135 168 470.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SMART SM00028 508 541 260.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SUPERFAMILY SSF48452 25 258 1.4E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Gene3D G3DSA:1.25.40.10 524 589 5.6E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Gene3D G3DSA:1.25.40.10 373 432 1.2E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SUPERFAMILY SSF48452 625 919 1.52E-29 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Gene3D G3DSA:1.25.40.10 590 668 1.8E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 TIGRFAM TIGR02917 PEP_TPR_lipo: putative PEP-CTERM system TPR-repeat lipoprotein 12 908 1.5E-148 T 29-03-2018 IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Pfam PF13432 Tetratricopeptide repeat 243 302 0.0086 T 29-03-2018 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Pfam PF13432 Tetratricopeptide repeat 655 712 2.7E-4 T 29-03-2018 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Pfam PF13432 Tetratricopeptide repeat 174 235 0.015 T 29-03-2018 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Pfam PF13432 Tetratricopeptide repeat 783 847 3.8E-5 T 29-03-2018 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Pfam PF13432 Tetratricopeptide repeat 854 910 6.5E-4 T 29-03-2018 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Gene3D G3DSA:1.25.40.10 866 932 1.5E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SUPERFAMILY SSF48452 192 437 1.05E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Gene3D G3DSA:1.25.40.10 20 106 3.3E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Gene3D G3DSA:1.25.40.10 820 865 2.0E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 Gene3D G3DSA:1.25.40.10 209 247 3.2E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08245 58ab1e4f94cc37b2104594e09769b109 941 SUPERFAMILY SSF48452 461 652 1.08E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS06620 9efc650cb0a4d00c643fc0f2e6b214d9 564 SMART SM00917 420 548 4.0E-23 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS06620 9efc650cb0a4d00c643fc0f2e6b214d9 564 SUPERFAMILY SSF51569 20 328 3.66E-98 T 29-03-2018 THSYN_RS06620 9efc650cb0a4d00c643fc0f2e6b214d9 564 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 38 54 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS06620 9efc650cb0a4d00c643fc0f2e6b214d9 564 SUPERFAMILY SSF89000 386 435 7.06E-12 T 29-03-2018 THSYN_RS06620 9efc650cb0a4d00c643fc0f2e6b214d9 564 SUPERFAMILY SSF110921 451 547 1.44E-24 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS06620 9efc650cb0a4d00c643fc0f2e6b214d9 564 Gene3D G3DSA:3.20.20.70 8 374 7.8E-103 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS06620 9efc650cb0a4d00c643fc0f2e6b214d9 564 Pfam PF08502 LeuA allosteric (dimerisation) domain 421 547 3.2E-23 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS06620 9efc650cb0a4d00c643fc0f2e6b214d9 564 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 3 549 50.889 T 29-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS06620 9efc650cb0a4d00c643fc0f2e6b214d9 564 Pfam PF00682 HMGL-like 31 308 1.4E-71 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 THSYN_RS06620 9efc650cb0a4d00c643fc0f2e6b214d9 564 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 241 254 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 309 5.5E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 Pfam PF01627 Hpt domain 683 750 2.9E-11 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 SUPERFAMILY SSF47384 229 310 1.86E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 Gene3D G3DSA:3.30.565.10 313 478 1.5E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 Gene3D G3DSA:1.20.120.160 676 810 3.1E-17 T 29-03-2018 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 SUPERFAMILY SSF47226 608 621 5.5E-19 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 SUPERFAMILY SSF47226 662 758 5.5E-19 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 471 9.3E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 Gene3D G3DSA:3.30.450.40 1 58 3.4E-4 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 Gene3D G3DSA:3.30.450.40 59 248 9.5E-22 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 SUPERFAMILY SSF55781 85 234 4.58E-15 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 SMART SM00073 673 771 0.0092 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 SMART SM00388 244 309 3.3E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 SMART SM00065 83 232 1.1E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 Gene3D G3DSA:1.10.287.130 249 305 7.8E-17 T 29-03-2018 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 SUPERFAMILY SSF55874 298 469 1.7E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 425 2.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 2.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 2.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 2.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 Pfam PF00072 Response regulator receiver domain 515 625 2.7E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 SUPERFAMILY SSF52172 510 636 3.13E-38 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 Pfam PF13185 GAF domain 83 222 1.0E-27 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 SMART SM00448 512 625 1.4E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 Gene3D G3DSA:3.40.50.2300 504 640 7.6E-39 T 29-03-2018 THSYN_RS27375 e311377bef74a5fda98a46f8cc13a3d2 859 SMART SM00387 356 472 5.5E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS11145 b59676b624200129816631d130bc8df4 230 Gene3D G3DSA:3.30.70.1070 149 230 4.9E-14 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 THSYN_RS11145 b59676b624200129816631d130bc8df4 230 SUPERFAMILY SSF110997 153 227 8.63E-15 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 THSYN_RS11145 b59676b624200129816631d130bc8df4 230 Pfam PF05036 Sporulation related domain 153 225 3.7E-12 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 THSYN_RS16310 c254bbbbf5343c4863eb0df3217d7bac 434 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 429 2.2E-179 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THSYN_RS16310 c254bbbbf5343c4863eb0df3217d7bac 434 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THSYN_RS16310 c254bbbbf5343c4863eb0df3217d7bac 434 SUPERFAMILY SSF52540 4 430 4.14E-171 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16310 c254bbbbf5343c4863eb0df3217d7bac 434 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THSYN_RS16310 c254bbbbf5343c4863eb0df3217d7bac 434 Gene3D G3DSA:3.90.170.10 267 431 2.6E-67 T 29-03-2018 THSYN_RS16310 c254bbbbf5343c4863eb0df3217d7bac 434 SMART SM00788 4 424 5.4E-283 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THSYN_RS16310 c254bbbbf5343c4863eb0df3217d7bac 434 Pfam PF00709 Adenylosuccinate synthetase 5 422 3.3E-174 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THSYN_RS16310 c254bbbbf5343c4863eb0df3217d7bac 434 Gene3D G3DSA:3.40.440.10 153 266 2.1E-24 T 29-03-2018 THSYN_RS16310 c254bbbbf5343c4863eb0df3217d7bac 434 Gene3D G3DSA:3.40.440.10 1 152 6.9E-53 T 29-03-2018 THSYN_RS16310 c254bbbbf5343c4863eb0df3217d7bac 434 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 434 207.341 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THSYN_RS10925 2dc317538f6573e5b46a2ed78242977d 286 Gene3D G3DSA:3.90.226.10 13 286 1.1E-67 T 29-03-2018 THSYN_RS10925 2dc317538f6573e5b46a2ed78242977d 286 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 282 38.184 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS10925 2dc317538f6573e5b46a2ed78242977d 286 Pfam PF01039 Carboxyl transferase domain 106 241 1.8E-13 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 THSYN_RS10925 2dc317538f6573e5b46a2ed78242977d 286 SUPERFAMILY SSF52096 26 282 4.04E-84 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS10925 2dc317538f6573e5b46a2ed78242977d 286 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 282 6.4E-128 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS10925 2dc317538f6573e5b46a2ed78242977d 286 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 230 241 2.3E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS10925 2dc317538f6573e5b46a2ed78242977d 286 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 201 218 2.3E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS10925 2dc317538f6573e5b46a2ed78242977d 286 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 164 182 2.3E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS10925 2dc317538f6573e5b46a2ed78242977d 286 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 130 144 2.3E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS10925 2dc317538f6573e5b46a2ed78242977d 286 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 252 261 2.3E-37 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS22760 fd628e965c572bee93215f32f48163f8 274 Gene3D G3DSA:3.90.550.10 20 204 4.0E-10 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22760 fd628e965c572bee93215f32f48163f8 274 Pfam PF13712 Glycosyltransferase like family 52 227 1.8E-27 T 29-03-2018 THSYN_RS22760 fd628e965c572bee93215f32f48163f8 274 SUPERFAMILY SSF53448 47 122 5.2E-14 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22760 fd628e965c572bee93215f32f48163f8 274 SUPERFAMILY SSF53448 149 227 5.2E-14 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS32820 d5bc66b4b935f895ae2789f63d63aae6 178 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 7 162 1.1E-57 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 THSYN_RS32820 d5bc66b4b935f895ae2789f63d63aae6 178 PIRSF PIRSF028301 1 175 3.2E-61 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 THSYN_RS32820 d5bc66b4b935f895ae2789f63d63aae6 178 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 11 161 3.6E-59 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 885 897 5.0E-40 T 29-03-2018 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 782 792 5.0E-40 T 29-03-2018 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 397 411 5.0E-40 T 29-03-2018 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 560 574 5.0E-40 T 29-03-2018 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 861 880 5.0E-40 T 29-03-2018 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 760 771 5.0E-40 T 29-03-2018 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 SMART SM00831 239 312 1.0E-27 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 SUPERFAMILY SSF81665 460 554 1.1E-118 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 SUPERFAMILY SSF81665 243 350 1.1E-118 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 SUPERFAMILY SSF81665 911 1122 1.1E-118 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 Pfam PF04654 Protein of unknown function, DUF599 22 219 2.9E-53 T 29-03-2018 IPR006747 Protein of unknown function DUF599 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 Pfam PF00702 haloacid dehalogenase-like hydrolase 557 875 7.9E-22 T 29-03-2018 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 SUPERFAMILY SSF81660 567 764 1.48E-54 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 Gene3D G3DSA:3.40.1110.10 523 767 2.2E-46 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 Gene3D G3DSA:2.70.150.10 248 460 5.5E-46 T 29-03-2018 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 562 568 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 Pfam PF00690 Cation transporter/ATPase, N-terminus 245 305 3.4E-15 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 Pfam PF00122 E1-E2 ATPase 349 539 2.6E-51 T 29-03-2018 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 SUPERFAMILY SSF56784 715 966 5.17E-64 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 SUPERFAMILY SSF56784 558 578 5.17E-64 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 Gene3D G3DSA:1.20.1110.10 775 1122 1.4E-89 T 29-03-2018 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 SUPERFAMILY SSF81653 350 459 2.88E-30 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 828 951 1.2E-33 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 318 579 5.4E-40 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 Pfam PF00689 Cation transporting ATPase, C-terminus 946 1117 3.9E-46 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 833 849 1.2E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 718 736 1.2E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 893 918 1.2E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS18235 2fb4b77e893dafd378369871ec21f87c 1132 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 861 877 1.2E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SUPERFAMILY SSF55781 265 441 3.71E-22 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SMART SM00091 601 667 0.074 T 29-03-2018 IPR000014 PAS domain THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SMART SM00091 461 530 2.2E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SUPERFAMILY SSF47226 1225 1238 4.32E-16 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SUPERFAMILY SSF47226 1266 1353 4.32E-16 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SUPERFAMILY SSF47384 719 800 1.28E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Pfam PF00072 Response regulator receiver domain 1131 1241 8.0E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Pfam PF00072 Response regulator receiver domain 984 1096 9.5E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 889 903 5.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 907 917 5.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 948 961 5.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 924 942 5.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Gene3D G3DSA:3.40.50.2300 977 1113 1.0E-29 T 29-03-2018 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SUPERFAMILY SSF55785 594 712 1.4E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SMART SM00448 1129 1242 5.8E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SMART SM00448 981 1097 4.7E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SUPERFAMILY SSF55874 788 959 2.1E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SUPERFAMILY SSF52172 979 1102 1.71E-30 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Pfam PF13426 PAS domain 612 713 3.2E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Pfam PF00989 PAS fold 462 568 2.0E-10 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Gene3D G3DSA:3.30.565.10 803 967 1.9E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Gene3D G3DSA:3.30.450.20 598 733 9.2E-24 T 29-03-2018 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 734 798 5.1E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SMART SM00387 848 964 9.3E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SUPERFAMILY SSF55785 448 569 8.38E-23 T 29-03-2018 IPR000014 PAS domain THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SMART SM00388 734 799 5.8E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 848 963 1.1E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SMART SM00065 293 450 7.0E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Gene3D G3DSA:3.30.450.40 269 464 7.9E-28 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SUPERFAMILY SSF52172 1127 1250 5.98E-37 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Gene3D G3DSA:3.30.450.20 465 597 5.4E-27 T 29-03-2018 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SMART SM00086 673 714 0.0021 T 29-03-2018 IPR001610 PAC motif THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 SMART SM00086 533 571 0.44 T 29-03-2018 IPR001610 PAC motif THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Gene3D G3DSA:1.20.120.160 1258 1367 3.9E-15 T 29-03-2018 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Gene3D G3DSA:1.10.287.130 734 795 1.1E-20 T 29-03-2018 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 600 721 3.9E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 460 577 1.6E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Pfam PF13185 GAF domain 296 441 6.2E-17 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Gene3D G3DSA:3.40.50.2300 1116 1254 3.8E-39 T 29-03-2018 THSYN_RS06705 dde9014d3199f50ada63c3df6da16d4a 1458 Pfam PF01627 Hpt domain 1286 1365 2.8E-9 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS32970 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.443.10 101 266 2.7E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS32970 14ff4d70670ad517e94d4969176bb694 282 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.9E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS32970 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.150.130 2 90 2.0E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS32970 14ff4d70670ad517e94d4969176bb694 282 SUPERFAMILY SSF56349 9 262 5.3E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS32970 14ff4d70670ad517e94d4969176bb694 282 Pfam PF00589 Phage integrase family 103 260 1.1E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS11570 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.443.10 101 266 2.7E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS11570 14ff4d70670ad517e94d4969176bb694 282 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.9E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS11570 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.150.130 2 90 2.0E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS11570 14ff4d70670ad517e94d4969176bb694 282 SUPERFAMILY SSF56349 9 262 5.3E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS11570 14ff4d70670ad517e94d4969176bb694 282 Pfam PF00589 Phage integrase family 103 260 1.1E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS31600 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.443.10 101 266 2.7E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS31600 14ff4d70670ad517e94d4969176bb694 282 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.9E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS31600 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.150.130 2 90 2.0E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS31600 14ff4d70670ad517e94d4969176bb694 282 SUPERFAMILY SSF56349 9 262 5.3E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS31600 14ff4d70670ad517e94d4969176bb694 282 Pfam PF00589 Phage integrase family 103 260 1.1E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS06370 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.443.10 101 266 2.7E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS06370 14ff4d70670ad517e94d4969176bb694 282 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.9E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS06370 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.150.130 2 90 2.0E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS06370 14ff4d70670ad517e94d4969176bb694 282 SUPERFAMILY SSF56349 9 262 5.3E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS06370 14ff4d70670ad517e94d4969176bb694 282 Pfam PF00589 Phage integrase family 103 260 1.1E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS27675 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.443.10 101 266 2.7E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS27675 14ff4d70670ad517e94d4969176bb694 282 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.9E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS27675 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.150.130 2 90 2.0E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS27675 14ff4d70670ad517e94d4969176bb694 282 SUPERFAMILY SSF56349 9 262 5.3E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS27675 14ff4d70670ad517e94d4969176bb694 282 Pfam PF00589 Phage integrase family 103 260 1.1E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS00795 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.443.10 101 266 2.7E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS00795 14ff4d70670ad517e94d4969176bb694 282 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.9E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS00795 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.150.130 2 90 2.0E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS00795 14ff4d70670ad517e94d4969176bb694 282 SUPERFAMILY SSF56349 9 262 5.3E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS00795 14ff4d70670ad517e94d4969176bb694 282 Pfam PF00589 Phage integrase family 103 260 1.1E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS24835 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.443.10 101 266 2.7E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS24835 14ff4d70670ad517e94d4969176bb694 282 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.9E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS24835 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.150.130 2 90 2.0E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS24835 14ff4d70670ad517e94d4969176bb694 282 SUPERFAMILY SSF56349 9 262 5.3E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS24835 14ff4d70670ad517e94d4969176bb694 282 Pfam PF00589 Phage integrase family 103 260 1.1E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS17020 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.443.10 101 266 2.7E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS17020 14ff4d70670ad517e94d4969176bb694 282 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.9E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS17020 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.150.130 2 90 2.0E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS17020 14ff4d70670ad517e94d4969176bb694 282 SUPERFAMILY SSF56349 9 262 5.3E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS17020 14ff4d70670ad517e94d4969176bb694 282 Pfam PF00589 Phage integrase family 103 260 1.1E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS11370 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.443.10 101 266 2.7E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS11370 14ff4d70670ad517e94d4969176bb694 282 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.9E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS11370 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.150.130 2 90 2.0E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS11370 14ff4d70670ad517e94d4969176bb694 282 SUPERFAMILY SSF56349 9 262 5.3E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS11370 14ff4d70670ad517e94d4969176bb694 282 Pfam PF00589 Phage integrase family 103 260 1.1E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS32510 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.443.10 101 266 2.7E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS32510 14ff4d70670ad517e94d4969176bb694 282 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.9E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS32510 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.150.130 2 90 2.0E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS32510 14ff4d70670ad517e94d4969176bb694 282 SUPERFAMILY SSF56349 9 262 5.3E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS32510 14ff4d70670ad517e94d4969176bb694 282 Pfam PF00589 Phage integrase family 103 260 1.1E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS02385 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.443.10 101 266 2.7E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS02385 14ff4d70670ad517e94d4969176bb694 282 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.9E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS02385 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.150.130 2 90 2.0E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS02385 14ff4d70670ad517e94d4969176bb694 282 SUPERFAMILY SSF56349 9 262 5.3E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS02385 14ff4d70670ad517e94d4969176bb694 282 Pfam PF00589 Phage integrase family 103 260 1.1E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS11590 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.443.10 101 266 2.7E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS11590 14ff4d70670ad517e94d4969176bb694 282 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.9E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS11590 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.150.130 2 90 2.0E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS11590 14ff4d70670ad517e94d4969176bb694 282 SUPERFAMILY SSF56349 9 262 5.3E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS11590 14ff4d70670ad517e94d4969176bb694 282 Pfam PF00589 Phage integrase family 103 260 1.1E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS01245 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.443.10 101 266 2.7E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS01245 14ff4d70670ad517e94d4969176bb694 282 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.9E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS01245 14ff4d70670ad517e94d4969176bb694 282 Gene3D G3DSA:1.10.150.130 2 90 2.0E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS01245 14ff4d70670ad517e94d4969176bb694 282 SUPERFAMILY SSF56349 9 262 5.3E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS01245 14ff4d70670ad517e94d4969176bb694 282 Pfam PF00589 Phage integrase family 103 260 1.1E-36 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS10170 7c1e6cb624fc0819f8f039615372db6f 671 SUPERFAMILY SSF53067 15 168 7.12E-11 T 29-03-2018 THSYN_RS10170 7c1e6cb624fc0819f8f039615372db6f 671 Gene3D G3DSA:3.30.420.40 189 371 3.7E-17 T 29-03-2018 THSYN_RS10170 7c1e6cb624fc0819f8f039615372db6f 671 Gene3D G3DSA:3.30.420.40 12 188 1.3E-18 T 29-03-2018 THSYN_RS10170 7c1e6cb624fc0819f8f039615372db6f 671 SUPERFAMILY SSF53067 180 396 7.33E-21 T 29-03-2018 THSYN_RS10170 7c1e6cb624fc0819f8f039615372db6f 671 Pfam PF00012 Hsp70 protein 142 259 3.1E-7 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS10465 51e7f0bbf10fad138b0d1c3667127a5d 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS10465 51e7f0bbf10fad138b0d1c3667127a5d 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS10465 51e7f0bbf10fad138b0d1c3667127a5d 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.1E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS10465 51e7f0bbf10fad138b0d1c3667127a5d 307 Gene3D G3DSA:3.40.190.10 88 176 3.0E-21 T 29-03-2018 THSYN_RS10465 51e7f0bbf10fad138b0d1c3667127a5d 307 Pfam PF03466 LysR substrate binding domain 88 297 2.5E-42 T 29-03-2018 IPR005119 LysR, substrate-binding THSYN_RS10465 51e7f0bbf10fad138b0d1c3667127a5d 307 Gene3D G3DSA:3.40.190.10 177 272 5.2E-21 T 29-03-2018 THSYN_RS10465 51e7f0bbf10fad138b0d1c3667127a5d 307 Gene3D G3DSA:1.10.10.10 1 82 8.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS10465 51e7f0bbf10fad138b0d1c3667127a5d 307 SUPERFAMILY SSF46785 2 87 7.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS10465 51e7f0bbf10fad138b0d1c3667127a5d 307 SUPERFAMILY SSF53850 88 301 3.1E-38 T 29-03-2018 THSYN_RS10465 51e7f0bbf10fad138b0d1c3667127a5d 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.1E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 Gene3D G3DSA:1.10.560.10 374 516 4.1E-24 T 29-03-2018 IPR027413 GroEL-like equatorial domain THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 Gene3D G3DSA:1.10.560.10 1 188 2.3E-42 T 29-03-2018 IPR027413 GroEL-like equatorial domain THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 SUPERFAMILY SSF52029 185 376 9.77E-83 T 29-03-2018 IPR027409 GroEL-like apical domain THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 SUPERFAMILY SSF54849 137 203 6.87E-25 T 29-03-2018 THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 PRINTS PR00298 60kDa chaperonin signature 268 291 8.2E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 PRINTS PR00298 60kDa chaperonin signature 398 419 8.2E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 PRINTS PR00298 60kDa chaperonin signature 83 110 8.2E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 PRINTS PR00298 60kDa chaperonin signature 350 375 8.2E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 PRINTS PR00298 60kDa chaperonin signature 27 53 8.2E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 524 4.0E-97 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 Hamap MF_00600 60 kDa chaperonin [groL]. 2 547 41.412 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 4.9E-254 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 SUPERFAMILY SSF48592 406 521 2.9E-76 T 29-03-2018 THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 SUPERFAMILY SSF48592 7 134 2.9E-76 T 29-03-2018 THSYN_RS02910 9aa5fd12204240f6abd899153687bc4b 548 Gene3D G3DSA:3.50.7.10 189 373 9.1E-97 T 29-03-2018 IPR027409 GroEL-like apical domain THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 Gene3D G3DSA:3.30.930.10 134 591 1.8E-114 T 29-03-2018 THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 589 34.628 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 523 537 1.7E-25 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 479 495 1.7E-25 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 193 205 1.7E-25 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 210 223 1.7E-25 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 Gene3D G3DSA:2.40.50.140 1 108 1.0E-27 T 29-03-2018 THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 Pfam PF01336 OB-fold nucleic acid binding domain 18 101 9.7E-18 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 587 5.1E-246 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 SUPERFAMILY SSF55681 116 295 8.11E-112 T 29-03-2018 THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 SUPERFAMILY SSF55681 429 589 8.11E-112 T 29-03-2018 THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 SUPERFAMILY SSF50249 1 105 4.95E-35 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 Pfam PF02938 GAD domain 311 410 2.4E-24 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 Pfam PF00152 tRNA synthetases class II (D, K and N) 120 563 9.5E-113 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS05370 3cb3b81250bac528878fce75e0993bd2 592 SUPERFAMILY SSF55261 293 424 1.72E-39 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 Gene3D G3DSA:2.40.240.10 346 465 1.0E-44 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 Gene3D G3DSA:2.40.240.10 466 550 4.0E-27 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 29 339 2.6E-107 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 Gene3D G3DSA:3.40.50.620 156 262 3.3E-17 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 Gene3D G3DSA:3.40.50.620 44 152 1.5E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 SUPERFAMILY SSF52374 12 339 1.31E-94 T 29-03-2018 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 30 554 1.0E-226 T 29-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 35 46 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 343 532 1.0E-54 T 29-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 SUPERFAMILY SSF50715 342 550 5.23E-65 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 PRINTS PR00987 Glutamyl-tRNA synthetase signature 212 222 3.6E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 PRINTS PR00987 Glutamyl-tRNA synthetase signature 61 74 3.6E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 PRINTS PR00987 Glutamyl-tRNA synthetase signature 32 44 3.6E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 PRINTS PR00987 Glutamyl-tRNA synthetase signature 46 57 3.6E-10 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 Gene3D G3DSA:3.40.50.620 22 43 0.19 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 Gene3D G3DSA:1.10.1160.10 263 340 7.8E-35 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 THSYN_RS13740 1e99eed3445f5b24405bfebf188e23e7 557 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 552 51.753 T 29-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 THSYN_RS13130 2bee17f96c47e8aa37bf14cd4143741a 339 PIRSF PIRSF000089 4 339 3.5E-105 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 THSYN_RS13130 2bee17f96c47e8aa37bf14cd4143741a 339 Gene3D G3DSA:3.40.50.1220 210 339 2.0E-52 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS13130 2bee17f96c47e8aa37bf14cd4143741a 339 Pfam PF01012 Electron transfer flavoprotein domain 8 181 9.6E-43 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 THSYN_RS13130 2bee17f96c47e8aa37bf14cd4143741a 339 SUPERFAMILY SSF52402 7 194 9.07E-51 T 29-03-2018 THSYN_RS13130 2bee17f96c47e8aa37bf14cd4143741a 339 SUPERFAMILY SSF52467 214 332 6.18E-44 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS13130 2bee17f96c47e8aa37bf14cd4143741a 339 Gene3D G3DSA:3.40.50.620 1 208 4.4E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS13130 2bee17f96c47e8aa37bf14cd4143741a 339 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 214 297 4.0E-32 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 THSYN_RS13130 2bee17f96c47e8aa37bf14cd4143741a 339 SMART SM00893 8 204 9.8E-46 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 THSYN_RS13130 2bee17f96c47e8aa37bf14cd4143741a 339 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 278 304 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 THSYN_RS01505 b9be9cf77d8d3f047a1fa1f9a45965a8 125 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 13 124 1.5E-31 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 THSYN_RS01505 b9be9cf77d8d3f047a1fa1f9a45965a8 125 Gene3D G3DSA:3.40.1350.10 18 124 1.5E-37 T 29-03-2018 THSYN_RS01505 b9be9cf77d8d3f047a1fa1f9a45965a8 125 Pfam PF02021 Uncharacterised protein family UPF0102 20 108 5.5E-29 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 THSYN_RS01505 b9be9cf77d8d3f047a1fa1f9a45965a8 125 Hamap MF_00048 UPF0102 protein YraN [yraN]. 12 121 22.844 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 THSYN_RS01505 b9be9cf77d8d3f047a1fa1f9a45965a8 125 SUPERFAMILY SSF52980 20 108 2.23E-20 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS05810 ba3f8367010ee16ccec25bf87dbea903 463 SUPERFAMILY SSF161098 189 450 1.59E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS05810 ba3f8367010ee16ccec25bf87dbea903 463 Gene3D G3DSA:1.10.3720.10 130 453 7.9E-35 T 29-03-2018 THSYN_RS05810 ba3f8367010ee16ccec25bf87dbea903 463 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 166 458 2.5E-86 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 THSYN_RS05810 ba3f8367010ee16ccec25bf87dbea903 463 Pfam PF12501 Phosphate ATP-binding cassette transporter 8 181 8.8E-35 T 29-03-2018 IPR022182 ABC transporter phosphate permease PstC, N-terminal domain GO:0006817 THSYN_RS05810 ba3f8367010ee16ccec25bf87dbea903 463 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 250 459 1.4E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS31140 7af6046f280a837147c06c7fb77a29c5 242 Gene3D G3DSA:3.40.50.1820 2 242 2.4E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS31140 7af6046f280a837147c06c7fb77a29c5 242 Pfam PF00756 Putative esterase 43 205 7.8E-12 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 THSYN_RS31140 7af6046f280a837147c06c7fb77a29c5 242 SUPERFAMILY SSF53474 4 239 3.57E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS27390 89d4dde5ba9f08522ecde2929e140af0 354 Gene3D G3DSA:3.30.1330.10 6 168 6.6E-34 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS27390 89d4dde5ba9f08522ecde2929e140af0 354 Pfam PF02769 AIR synthase related protein, C-terminal domain 175 349 9.0E-30 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS27390 89d4dde5ba9f08522ecde2929e140af0 354 Gene3D G3DSA:3.90.650.10 170 352 9.3E-43 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS27390 89d4dde5ba9f08522ecde2929e140af0 354 TIGRFAM TIGR00476 selD: selenide, water dikinase 13 322 2.7E-125 T 29-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 THSYN_RS27390 89d4dde5ba9f08522ecde2929e140af0 354 PIRSF PIRSF036407 8 354 7.1E-108 T 29-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 THSYN_RS27390 89d4dde5ba9f08522ecde2929e140af0 354 SUPERFAMILY SSF55326 13 167 3.29E-39 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS27390 89d4dde5ba9f08522ecde2929e140af0 354 Pfam PF00586 AIR synthase related protein, N-terminal domain 56 163 1.9E-18 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS27390 89d4dde5ba9f08522ecde2929e140af0 354 SUPERFAMILY SSF56042 170 348 1.24E-47 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS27390 89d4dde5ba9f08522ecde2929e140af0 354 Hamap MF_00625 Selenide, water dikinase [selD]. 11 354 41.371 T 29-03-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 THSYN_RS10280 d825efb8dce9803452b21192029b16d6 946 SUPERFAMILY SSF48403 701 754 5.93E-10 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS10280 d825efb8dce9803452b21192029b16d6 946 SMART SM00248 710 739 0.005 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS10280 d825efb8dce9803452b21192029b16d6 946 Gene3D G3DSA:1.25.40.20 568 855 7.0E-11 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS10280 d825efb8dce9803452b21192029b16d6 946 SUPERFAMILY SSF52540 272 502 7.48E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10280 d825efb8dce9803452b21192029b16d6 946 SUPERFAMILY SSF52540 532 556 7.48E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10280 d825efb8dce9803452b21192029b16d6 946 SUPERFAMILY SSF52540 125 221 7.48E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10280 d825efb8dce9803452b21192029b16d6 946 Gene3D G3DSA:3.40.50.300 392 567 1.2E-14 T 29-03-2018 THSYN_RS10280 d825efb8dce9803452b21192029b16d6 946 Gene3D G3DSA:3.40.50.300 120 391 1.1E-18 T 29-03-2018 THSYN_RS10280 d825efb8dce9803452b21192029b16d6 946 Pfam PF00023 Ankyrin repeat 711 741 3.3E-4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 411 428 9.8E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 428 448 9.8E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 SUPERFAMILY SSF52172 1 181 4.7E-41 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 Gene3D G3DSA:1.10.8.60 311 403 1.8E-22 T 29-03-2018 THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 Gene3D G3DSA:3.40.50.300 145 310 1.1E-25 T 29-03-2018 THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 224 239 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 Gene3D G3DSA:3.40.50.2300 1 144 4.6E-32 T 29-03-2018 THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 Pfam PF00158 Sigma-54 interaction domain 139 304 1.3E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 SUPERFAMILY SSF52540 139 380 5.86E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 Pfam PF02954 Bacterial regulatory protein, Fis family 405 445 5.3E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 SUPERFAMILY SSF46689 353 447 1.12E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 SMART SM00382 158 301 1.0E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 Pfam PF00072 Response regulator receiver domain 7 113 3.8E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 SMART SM00448 4 115 9.7E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 352 361 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site THSYN_RS00910 edb7ed1244d83f3a56bc19c0928539e1 448 Gene3D G3DSA:1.10.10.60 404 448 3.5E-15 T 29-03-2018 THSYN_RS31105 3f9733f37ff3e62f0703f6bfcb66003e 446 Pfam PF11902 Protein of unknown function (DUF3422) 6 425 4.6E-162 T 29-03-2018 IPR021830 Protein of unknown function DUF3422 THSYN_RS05970 b1f3a643b8c74fb69a89ebb7a6a6c597 352 SUPERFAMILY SSF51735 1 334 4.6E-92 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS05970 b1f3a643b8c74fb69a89ebb7a6a6c597 352 Gene3D G3DSA:3.90.25.10 194 348 2.4E-50 T 29-03-2018 THSYN_RS05970 b1f3a643b8c74fb69a89ebb7a6a6c597 352 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 324 1.7E-92 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS05970 b1f3a643b8c74fb69a89ebb7a6a6c597 352 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 4 336 5.4E-148 T 29-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 THSYN_RS05970 b1f3a643b8c74fb69a89ebb7a6a6c597 352 Gene3D G3DSA:3.40.50.720 1 193 3.6E-38 T 29-03-2018 THSYN_RS23475 e5e9202661e470b7f5f27ba5389f4f90 348 Gene3D G3DSA:3.30.420.40 166 199 0.015 T 29-03-2018 THSYN_RS23475 e5e9202661e470b7f5f27ba5389f4f90 348 Gene3D G3DSA:3.30.420.40 9 165 2.8E-39 T 29-03-2018 THSYN_RS23475 e5e9202661e470b7f5f27ba5389f4f90 348 SUPERFAMILY SSF53067 155 340 1.66E-48 T 29-03-2018 THSYN_RS23475 e5e9202661e470b7f5f27ba5389f4f90 348 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 10 339 9.6E-159 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THSYN_RS23475 e5e9202661e470b7f5f27ba5389f4f90 348 Pfam PF06723 MreB/Mbl protein 12 338 1.2E-145 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THSYN_RS23475 e5e9202661e470b7f5f27ba5389f4f90 348 Gene3D G3DSA:3.90.640.10 200 257 8.7E-26 T 29-03-2018 THSYN_RS23475 e5e9202661e470b7f5f27ba5389f4f90 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 5.1E-64 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THSYN_RS23475 e5e9202661e470b7f5f27ba5389f4f90 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 5.1E-64 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THSYN_RS23475 e5e9202661e470b7f5f27ba5389f4f90 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 5.1E-64 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THSYN_RS23475 e5e9202661e470b7f5f27ba5389f4f90 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 5.1E-64 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THSYN_RS23475 e5e9202661e470b7f5f27ba5389f4f90 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 5.1E-64 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THSYN_RS23475 e5e9202661e470b7f5f27ba5389f4f90 348 SUPERFAMILY SSF53067 10 153 7.62E-38 T 29-03-2018 THSYN_RS23475 e5e9202661e470b7f5f27ba5389f4f90 348 Gene3D G3DSA:3.30.420.40 258 322 1.5E-9 T 29-03-2018 THSYN_RS04030 f3badc38720a8ab0429136157bdcae7d 432 SUPERFAMILY SSF56281 18 297 1.97E-47 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS04030 f3badc38720a8ab0429136157bdcae7d 432 Pfam PF00258 Flavodoxin 277 408 1.9E-11 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 THSYN_RS04030 f3badc38720a8ab0429136157bdcae7d 432 SMART SM00849 48 241 2.1E-31 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS04030 f3badc38720a8ab0429136157bdcae7d 432 SUPERFAMILY SSF52218 275 417 1.7E-37 T 29-03-2018 IPR029039 Flavoprotein-like domain THSYN_RS04030 f3badc38720a8ab0429136157bdcae7d 432 ProSitePatterns PS00201 Flavodoxin signature. 277 293 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 THSYN_RS04030 f3badc38720a8ab0429136157bdcae7d 432 Gene3D G3DSA:3.40.50.360 269 426 7.0E-25 T 29-03-2018 IPR029039 Flavoprotein-like domain THSYN_RS04030 f3badc38720a8ab0429136157bdcae7d 432 PIRSF PIRSF005243 14 421 1.2E-128 T 29-03-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 THSYN_RS04030 f3badc38720a8ab0429136157bdcae7d 432 Pfam PF00753 Metallo-beta-lactamase superfamily 48 186 2.7E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS04030 f3badc38720a8ab0429136157bdcae7d 432 Gene3D G3DSA:3.60.15.10 9 262 1.3E-40 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS13040 330cccc3645918264df451c4b664663d 270 Pfam PF00005 ABC transporter 25 172 7.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS13040 330cccc3645918264df451c4b664663d 270 SMART SM00382 33 221 1.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS13040 330cccc3645918264df451c4b664663d 270 Gene3D G3DSA:3.40.50.300 3 242 1.3E-61 T 29-03-2018 THSYN_RS13040 330cccc3645918264df451c4b664663d 270 SUPERFAMILY SSF52540 5 236 2.45E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12695 7abb5354a94e8a0b9e7b183cb55f3f44 294 SUPERFAMILY SSF56104 4 293 3.01E-100 T 29-03-2018 THSYN_RS12695 7abb5354a94e8a0b9e7b183cb55f3f44 294 ProSitePatterns PS01058 SAICAR synthetase signature 2. 205 213 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THSYN_RS12695 7abb5354a94e8a0b9e7b183cb55f3f44 294 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 12 293 26.337 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THSYN_RS12695 7abb5354a94e8a0b9e7b183cb55f3f44 294 Gene3D G3DSA:3.30.470.20 112 249 9.3E-55 T 29-03-2018 THSYN_RS12695 7abb5354a94e8a0b9e7b183cb55f3f44 294 ProSitePatterns PS01057 SAICAR synthetase signature 1. 106 120 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THSYN_RS12695 7abb5354a94e8a0b9e7b183cb55f3f44 294 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 15 292 2.8E-73 T 29-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 THSYN_RS12695 7abb5354a94e8a0b9e7b183cb55f3f44 294 Gene3D G3DSA:3.30.200.20 5 111 3.1E-30 T 29-03-2018 THSYN_RS12695 7abb5354a94e8a0b9e7b183cb55f3f44 294 Pfam PF01259 SAICAR synthetase 15 268 1.9E-98 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 Pfam PF02954 Bacterial regulatory protein, Fis family 422 461 4.9E-15 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 SMART SM00448 5 116 7.0E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 Gene3D G3DSA:3.40.50.2300 1 134 2.6E-35 T 29-03-2018 THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 7 461 1.9E-221 T 29-03-2018 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 Pfam PF00158 Sigma-54 interaction domain 139 306 1.5E-71 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 SMART SM00382 159 302 6.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 Gene3D G3DSA:1.10.8.60 312 380 7.1E-23 T 29-03-2018 THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 Gene3D G3DSA:1.10.10.60 381 464 1.2E-18 T 29-03-2018 THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 SUPERFAMILY SSF46689 379 464 1.0E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 Gene3D G3DSA:3.40.50.300 135 311 4.2E-32 T 29-03-2018 THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 SUPERFAMILY SSF52540 138 382 1.64E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 Pfam PF00072 Response regulator receiver domain 7 115 1.9E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 352 361 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 163 176 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 SUPERFAMILY SSF52172 4 184 1.14E-43 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 444 464 2.6E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS00060 27b30b96310eb698a4b8f0a75f2ea399 472 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 427 444 2.6E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS13615 76e923a1614d1b47fbc87b80f1adaa51 292 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 3 82 1.2E-26 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal THSYN_RS13615 76e923a1614d1b47fbc87b80f1adaa51 292 Gene3D G3DSA:3.90.260.10 167 248 9.0E-5 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS13615 76e923a1614d1b47fbc87b80f1adaa51 292 SUPERFAMILY SSF54001 109 271 1.12E-40 T 29-03-2018 THSYN_RS13615 76e923a1614d1b47fbc87b80f1adaa51 292 Pfam PF01841 Transglutaminase-like superfamily 151 244 1.6E-17 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS13615 76e923a1614d1b47fbc87b80f1adaa51 292 SMART SM00460 176 246 3.0E-17 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS23485 058cea50fac8925a193504fb39734f6f 95 SUPERFAMILY SSF141000 3 93 1.31E-27 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THSYN_RS23485 058cea50fac8925a193504fb39734f6f 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 90 9.0E-16 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THSYN_RS23485 058cea50fac8925a193504fb39734f6f 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 6.2E-29 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THSYN_RS23485 058cea50fac8925a193504fb39734f6f 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 22.485 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THSYN_RS08575 f16b290953337e8be12f241ea4b49114 461 Gene3D G3DSA:3.40.50.620 14 227 3.0E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS08575 f16b290953337e8be12f241ea4b49114 461 Pfam PF09179 TilS substrate binding domain 249 315 1.6E-16 T 29-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THSYN_RS08575 f16b290953337e8be12f241ea4b49114 461 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 371 407 1.6E-12 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THSYN_RS08575 f16b290953337e8be12f241ea4b49114 461 Pfam PF11734 TilS substrate C-terminal domain 361 426 2.3E-21 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THSYN_RS08575 f16b290953337e8be12f241ea4b49114 461 Pfam PF01171 PP-loop family 22 199 1.1E-47 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 THSYN_RS08575 f16b290953337e8be12f241ea4b49114 461 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 9 308 21.8 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THSYN_RS08575 f16b290953337e8be12f241ea4b49114 461 SUPERFAMILY SSF82829 246 320 4.32E-18 T 29-03-2018 THSYN_RS08575 f16b290953337e8be12f241ea4b49114 461 SUPERFAMILY SSF52402 16 230 4.63E-56 T 29-03-2018 THSYN_RS08575 f16b290953337e8be12f241ea4b49114 461 SMART SM00977 361 427 3.8E-19 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THSYN_RS08575 f16b290953337e8be12f241ea4b49114 461 SUPERFAMILY SSF56037 336 422 1.86E-20 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 THSYN_RS08575 f16b290953337e8be12f241ea4b49114 461 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 22 203 1.2E-45 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THSYN_RS05775 04e8ba001190cdb7d58fb0d4bca4a41c 69 SUPERFAMILY SSF46689 4 65 1.49E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS05775 04e8ba001190cdb7d58fb0d4bca4a41c 69 Pfam PF04255 Protein of unknown function (DUF433) 5 61 1.1E-20 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS05775 04e8ba001190cdb7d58fb0d4bca4a41c 69 Gene3D G3DSA:1.10.10.10 5 67 2.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25600 14e6b9f6e3cf812fe9ead8e605f2364d 568 Pfam PF01609 Transposase DDE domain 189 463 2.6E-15 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS25600 14e6b9f6e3cf812fe9ead8e605f2364d 568 Gene3D G3DSA:3.90.350.10 147 446 4.4E-36 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS25600 14e6b9f6e3cf812fe9ead8e605f2364d 568 SUPERFAMILY SSF53098 399 470 5.61E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS25600 14e6b9f6e3cf812fe9ead8e605f2364d 568 SUPERFAMILY SSF53098 355 372 5.61E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS32870 14e6b9f6e3cf812fe9ead8e605f2364d 568 Pfam PF01609 Transposase DDE domain 189 463 2.6E-15 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS32870 14e6b9f6e3cf812fe9ead8e605f2364d 568 Gene3D G3DSA:3.90.350.10 147 446 4.4E-36 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS32870 14e6b9f6e3cf812fe9ead8e605f2364d 568 SUPERFAMILY SSF53098 399 470 5.61E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS32870 14e6b9f6e3cf812fe9ead8e605f2364d 568 SUPERFAMILY SSF53098 355 372 5.61E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS19930 14e6b9f6e3cf812fe9ead8e605f2364d 568 Pfam PF01609 Transposase DDE domain 189 463 2.6E-15 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS19930 14e6b9f6e3cf812fe9ead8e605f2364d 568 Gene3D G3DSA:3.90.350.10 147 446 4.4E-36 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS19930 14e6b9f6e3cf812fe9ead8e605f2364d 568 SUPERFAMILY SSF53098 399 470 5.61E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS19930 14e6b9f6e3cf812fe9ead8e605f2364d 568 SUPERFAMILY SSF53098 355 372 5.61E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS08715 dc3d062e61898c5c63fc06bc2e33794d 668 SMART SM00052 420 660 2.6E-10 T 29-03-2018 IPR001633 EAL domain THSYN_RS08715 dc3d062e61898c5c63fc06bc2e33794d 668 Pfam PF00072 Response regulator receiver domain 137 248 5.2E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08715 dc3d062e61898c5c63fc06bc2e33794d 668 Gene3D G3DSA:3.40.50.2300 49 130 0.023 T 29-03-2018 THSYN_RS08715 dc3d062e61898c5c63fc06bc2e33794d 668 Gene3D G3DSA:3.40.50.2300 131 404 5.9E-33 T 29-03-2018 THSYN_RS08715 dc3d062e61898c5c63fc06bc2e33794d 668 Gene3D G3DSA:3.20.20.450 423 667 3.5E-36 T 29-03-2018 IPR001633 EAL domain THSYN_RS08715 dc3d062e61898c5c63fc06bc2e33794d 668 SUPERFAMILY SSF141868 426 661 4.32E-32 T 29-03-2018 IPR001633 EAL domain THSYN_RS08715 dc3d062e61898c5c63fc06bc2e33794d 668 SMART SM00448 135 248 1.5E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08715 dc3d062e61898c5c63fc06bc2e33794d 668 SUPERFAMILY SSF52172 135 262 4.7E-33 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS08715 dc3d062e61898c5c63fc06bc2e33794d 668 Pfam PF00563 EAL domain 428 655 4.8E-29 T 29-03-2018 IPR001633 EAL domain THSYN_RS23895 d71a275d1ccc471f06642def6886fc30 92 PIRSF PIRSF002144 1 92 1.3E-31 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23895 d71a275d1ccc471f06642def6886fc30 92 SUPERFAMILY SSF54570 3 84 7.72E-35 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23895 d71a275d1ccc471f06642def6886fc30 92 Pfam PF00203 Ribosomal protein S19 3 83 1.9E-35 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23895 d71a275d1ccc471f06642def6886fc30 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 2 91 3.0E-43 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 THSYN_RS23895 d71a275d1ccc471f06642def6886fc30 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.728 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23895 d71a275d1ccc471f06642def6886fc30 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23895 d71a275d1ccc471f06642def6886fc30 92 Gene3D G3DSA:3.30.860.10 1 92 6.1E-38 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23895 d71a275d1ccc471f06642def6886fc30 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.9E-22 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23895 d71a275d1ccc471f06642def6886fc30 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.9E-22 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23895 d71a275d1ccc471f06642def6886fc30 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.9E-22 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS13540 b41f9cd94ff741692aa4d8d419238ed6 122 SUPERFAMILY SSF54995 1 102 1.28E-35 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13540 b41f9cd94ff741692aa4d8d419238ed6 122 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 92 7.0E-33 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13540 b41f9cd94ff741692aa4d8d419238ed6 122 Pfam PF01250 Ribosomal protein S6 3 91 1.1E-25 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13540 b41f9cd94ff741692aa4d8d419238ed6 122 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.079 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 THSYN_RS13540 b41f9cd94ff741692aa4d8d419238ed6 122 Gene3D G3DSA:3.30.70.60 1 100 1.9E-29 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 THSYN_RS29830 a41b84853de098acf444f285b6df3b22 334 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 302 1.3E-75 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B THSYN_RS29830 a41b84853de098acf444f285b6df3b22 334 SUPERFAMILY SSF50891 206 308 2.73E-8 T 29-03-2018 IPR029000 Cyclophilin-like domain THSYN_RS29830 a41b84853de098acf444f285b6df3b22 334 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 4 324 5.9E-74 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B THSYN_RS29830 a41b84853de098acf444f285b6df3b22 334 SMART SM00797 25 319 3.3E-97 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B THSYN_RS28505 9c854b636f452a132ee4424f0b4a81f2 612 Pfam PF00474 Sodium:solute symporter family 397 531 5.7E-16 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THSYN_RS28505 9c854b636f452a132ee4424f0b4a81f2 612 Pfam PF00474 Sodium:solute symporter family 39 346 5.3E-38 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THSYN_RS28505 9c854b636f452a132ee4424f0b4a81f2 612 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 513 533 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 THSYN_RS15215 961bf59706196365bd4729c200f47e0d 356 SUPERFAMILY SSF111369 115 297 3.66E-6 T 29-03-2018 THSYN_RS15215 961bf59706196365bd4729c200f47e0d 356 Gene3D G3DSA:2.40.50.100 47 115 1.6E-10 T 29-03-2018 THSYN_RS15215 961bf59706196365bd4729c200f47e0d 356 SUPERFAMILY SSF111369 41 103 5.23E-6 T 29-03-2018 THSYN_RS15215 961bf59706196365bd4729c200f47e0d 356 Gene3D G3DSA:1.10.287.470 117 183 2.5E-7 T 29-03-2018 THSYN_RS15215 961bf59706196365bd4729c200f47e0d 356 Gene3D G3DSA:1.20.1600.10 184 319 3.0E-5 T 29-03-2018 THSYN_RS15215 961bf59706196365bd4729c200f47e0d 356 Pfam PF13437 HlyD family secretion protein 215 319 9.2E-13 T 29-03-2018 THSYN_RS31115 b349f33f4040692c6a31411bfdf172e8 414 Pfam PF05235 CHAD domain 114 344 3.6E-56 T 29-03-2018 IPR007899 CHAD domain THSYN_RS31115 b349f33f4040692c6a31411bfdf172e8 414 SMART SM00880 113 378 3.6E-68 T 29-03-2018 IPR007899 CHAD domain THSYN_RS23365 ccd2cd5b2311f47fa83a6cd3ce12158a 211 Pfam PF11103 Protein of unknown function (DUF2887) 3 97 4.4E-18 T 29-03-2018 IPR022573 Protein of unknown function DUF2887 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 Gene3D G3DSA:2.30.42.10 388 480 4.1E-17 T 29-03-2018 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 Pfam PF13365 Trypsin-like peptidase domain 100 233 6.7E-35 T 29-03-2018 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 PRINTS PR00834 HtrA/DegQ protease family signature 204 221 1.7E-49 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 PRINTS PR00834 HtrA/DegQ protease family signature 312 324 1.7E-49 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 PRINTS PR00834 HtrA/DegQ protease family signature 130 150 1.7E-49 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 PRINTS PR00834 HtrA/DegQ protease family signature 109 121 1.7E-49 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 PRINTS PR00834 HtrA/DegQ protease family signature 226 243 1.7E-49 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 PRINTS PR00834 HtrA/DegQ protease family signature 170 194 1.7E-49 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 SUPERFAMILY SSF50156 241 367 5.8E-22 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 SMART SM00228 389 469 1.1E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 SMART SM00228 272 354 3.8E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 Gene3D G3DSA:2.40.10.10 27 170 7.7E-37 T 29-03-2018 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 Gene3D G3DSA:2.30.42.10 274 377 8.0E-23 T 29-03-2018 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 Gene3D G3DSA:2.40.10.10 171 273 5.5E-39 T 29-03-2018 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 SUPERFAMILY SSF50494 97 282 1.29E-64 T 29-03-2018 IPR009003 Peptidase S1, PA clan THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 SUPERFAMILY SSF50494 14 50 1.29E-64 T 29-03-2018 IPR009003 Peptidase S1, PA clan THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 Pfam PF13180 PDZ domain 272 362 5.8E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 Pfam PF13180 PDZ domain 405 470 1.7E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 31 475 3.1E-144 T 29-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 THSYN_RS08410 505c07993ba03e735886c8f3a43636fc 481 SUPERFAMILY SSF50156 390 478 3.02E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 Gene3D G3DSA:2.60.40.10 1230 1321 1.4E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 Gene3D G3DSA:3.40.50.200 256 625 4.3E-27 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 SUPERFAMILY SSF49373 720 798 6.54E-7 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 SUPERFAMILY SSF52743 266 589 2.62E-42 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 Gene3D G3DSA:2.120.10.30 838 1176 3.0E-6 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 SMART SM00944 45 180 7.6E-36 T 29-03-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 SUPERFAMILY SSF54897 53 190 4.08E-34 T 29-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 SUPERFAMILY SSF49299 1334 1424 3.14E-7 T 29-03-2018 IPR000601 PKD domain THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 SUPERFAMILY SSF63446 1425 1475 5.79E-5 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 Gene3D G3DSA:2.60.40.10 716 816 2.0E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 Gene3D G3DSA:2.60.40.10 626 713 3.1E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 527 537 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 SUPERFAMILY SSF49373 624 698 4.71E-7 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 SUPERFAMILY SSF63829 853 1022 6.08E-11 T 29-03-2018 THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 SUPERFAMILY SSF63829 1073 1135 6.08E-11 T 29-03-2018 THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 Pfam PF00082 Subtilase family 340 546 1.0E-7 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 Pfam PF09286 Pro-kumamolisin, activation domain 53 179 2.7E-23 T 29-03-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 THSYN_RS09795 db9d74ec18cce01426f236f3a793565b 1487 Gene3D G3DSA:3.40.1850.10 1342 1426 1.5E-19 T 29-03-2018 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 726 742 3.4E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 757 782 3.4E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 SUPERFAMILY SSF56784 510 529 3.59E-54 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 SUPERFAMILY SSF56784 583 825 3.59E-54 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 250 827 3.7E-173 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 Pfam PF00122 E1-E2 ATPase 314 489 8.2E-53 T 29-03-2018 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 232 829 1.8E-155 T 29-03-2018 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 ProSitePatterns PS01229 Hypothetical cof family signature 2. 726 748 - T 29-03-2018 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 Gene3D G3DSA:1.20.1110.10 690 823 5.5E-33 T 29-03-2018 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 Gene3D G3DSA:1.20.1110.10 280 523 1.4E-40 T 29-03-2018 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 726 745 3.8E-27 T 29-03-2018 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 511 525 3.8E-27 T 29-03-2018 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 749 761 3.8E-27 T 29-03-2018 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 673 683 3.8E-27 T 29-03-2018 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 363 377 3.8E-27 T 29-03-2018 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 SUPERFAMILY SSF81665 775 808 1.83E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 SUPERFAMILY SSF81665 414 505 1.83E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 SUPERFAMILY SSF81665 283 317 1.83E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 Gene3D G3DSA:3.30.70.100 95 168 5.4E-17 T 29-03-2018 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 513 519 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 Pfam PF00702 haloacid dehalogenase-like hydrolase 507 740 4.3E-35 T 29-03-2018 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 Gene3D G3DSA:3.40.1110.10 524 689 8.5E-31 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 ProSitePatterns PS01047 Heavy-metal-associated domain. 104 133 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 SUPERFAMILY SSF55008 99 169 3.27E-18 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 Pfam PF00403 Heavy-metal-associated domain 104 161 1.2E-9 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 652 813 4.8E-39 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 287 527 3.3E-37 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 SUPERFAMILY SSF81653 316 413 1.7E-27 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 THSYN_RS08875 61fb6baf2c3ef3e024f4fc00359bb2d2 836 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 14 92 7.4E-21 T 29-03-2018 IPR021993 Putative metal-binding domain of cation transport ATPase THSYN_RS16210 f558b0626c3eb918064260d071c087b1 356 Pfam PF02504 Fatty acid synthesis protein 6 324 2.2E-104 T 29-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 THSYN_RS16210 f558b0626c3eb918064260d071c087b1 356 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 341 144.31 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 THSYN_RS16210 f558b0626c3eb918064260d071c087b1 356 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 7 334 2.6E-104 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 THSYN_RS16210 f558b0626c3eb918064260d071c087b1 356 PIRSF PIRSF002465 3 339 1.4E-126 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 THSYN_RS16210 f558b0626c3eb918064260d071c087b1 356 SUPERFAMILY SSF53659 5 336 1.19E-103 T 29-03-2018 THSYN_RS16210 f558b0626c3eb918064260d071c087b1 356 Gene3D G3DSA:3.40.718.10 2 338 3.1E-108 T 29-03-2018 THSYN_RS01680 a2bb3a40ab46e538319cd43946da3f72 301 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 295 31.158 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 THSYN_RS01680 a2bb3a40ab46e538319cd43946da3f72 301 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 288 1.4E-72 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 THSYN_RS01680 a2bb3a40ab46e538319cd43946da3f72 301 PIRSF PIRSF000401 1 297 1.1E-76 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 THSYN_RS01680 a2bb3a40ab46e538319cd43946da3f72 301 SUPERFAMILY SSF53335 63 274 1.92E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS01680 a2bb3a40ab46e538319cd43946da3f72 301 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 295 3.0E-80 T 29-03-2018 THSYN_RS01680 a2bb3a40ab46e538319cd43946da3f72 301 Gene3D G3DSA:3.40.50.150 101 297 1.6E-32 T 29-03-2018 THSYN_RS02055 34a026511d09e233bf914fdafe94cb05 109 SUPERFAMILY SSF69754 3 96 4.84E-35 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 THSYN_RS02055 34a026511d09e233bf914fdafe94cb05 109 Gene3D G3DSA:3.30.160.100 1 96 7.1E-31 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 THSYN_RS02055 34a026511d09e233bf914fdafe94cb05 109 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 96 3.7E-32 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 THSYN_RS02055 34a026511d09e233bf914fdafe94cb05 109 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 92 2.1E-27 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 THSYN_RS25665 59ed2b63c4e422d4ba606c5932fcdf0e 1174 SUPERFAMILY SSF52540 219 272 2.3E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS25665 59ed2b63c4e422d4ba606c5932fcdf0e 1174 SUPERFAMILY SSF52540 1030 1161 2.3E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS25665 59ed2b63c4e422d4ba606c5932fcdf0e 1174 SUPERFAMILY SSF52540 1 91 2.3E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS25665 59ed2b63c4e422d4ba606c5932fcdf0e 1174 Pfam PF13514 AAA domain 1 220 4.6E-66 T 29-03-2018 THSYN_RS25665 59ed2b63c4e422d4ba606c5932fcdf0e 1174 Gene3D G3DSA:3.40.50.300 1 1165 7.5E-21 T 29-03-2018 THSYN_RS16600 75166f2580025db7d9358ab7fe08bbd7 366 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 340 1.6E-85 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 THSYN_RS16600 75166f2580025db7d9358ab7fe08bbd7 366 Gene3D G3DSA:3.20.20.70 1 366 4.3E-128 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS16600 75166f2580025db7d9358ab7fe08bbd7 366 SUPERFAMILY SSF51395 5 363 6.64E-129 T 29-03-2018 THSYN_RS20665 c743523ee503feb2408132c697cf89a3 348 SUPERFAMILY SSF55326 20 166 2.39E-32 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS20665 c743523ee503feb2408132c697cf89a3 348 Pfam PF00586 AIR synthase related protein, N-terminal domain 62 162 2.2E-15 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS20665 c743523ee503feb2408132c697cf89a3 348 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 325 2.3E-28 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS20665 c743523ee503feb2408132c697cf89a3 348 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 18 348 1.2E-136 T 29-03-2018 IPR011854 Hydrogenase expression/formation protein HypE THSYN_RS20665 c743523ee503feb2408132c697cf89a3 348 SUPERFAMILY SSF56042 169 344 1.64E-46 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS20665 c743523ee503feb2408132c697cf89a3 348 Gene3D G3DSA:3.90.650.10 168 336 4.4E-40 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS20665 c743523ee503feb2408132c697cf89a3 348 Gene3D G3DSA:3.30.1330.10 14 165 3.0E-26 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS20665 c743523ee503feb2408132c697cf89a3 348 PIRSF PIRSF005644 13 348 3.8E-122 T 29-03-2018 IPR011854 Hydrogenase expression/formation protein HypE THSYN_RS10150 a42e6561dabcfa54905257fedb1e9b0b 434 SUPERFAMILY SSF53098 40 406 1.52E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS10150 a42e6561dabcfa54905257fedb1e9b0b 434 Gene3D G3DSA:3.90.350.10 55 357 1.0E-17 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS10150 a42e6561dabcfa54905257fedb1e9b0b 434 Pfam PF13546 DDE superfamily endonuclease 11 274 5.0E-52 T 29-03-2018 THSYN_RS10770 a42e6561dabcfa54905257fedb1e9b0b 434 SUPERFAMILY SSF53098 40 406 1.52E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS10770 a42e6561dabcfa54905257fedb1e9b0b 434 Gene3D G3DSA:3.90.350.10 55 357 1.0E-17 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS10770 a42e6561dabcfa54905257fedb1e9b0b 434 Pfam PF13546 DDE superfamily endonuclease 11 274 5.0E-52 T 29-03-2018 THSYN_RS19125 a42e6561dabcfa54905257fedb1e9b0b 434 SUPERFAMILY SSF53098 40 406 1.52E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS19125 a42e6561dabcfa54905257fedb1e9b0b 434 Gene3D G3DSA:3.90.350.10 55 357 1.0E-17 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS19125 a42e6561dabcfa54905257fedb1e9b0b 434 Pfam PF13546 DDE superfamily endonuclease 11 274 5.0E-52 T 29-03-2018 THSYN_RS30540 a42e6561dabcfa54905257fedb1e9b0b 434 SUPERFAMILY SSF53098 40 406 1.52E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS30540 a42e6561dabcfa54905257fedb1e9b0b 434 Gene3D G3DSA:3.90.350.10 55 357 1.0E-17 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS30540 a42e6561dabcfa54905257fedb1e9b0b 434 Pfam PF13546 DDE superfamily endonuclease 11 274 5.0E-52 T 29-03-2018 THSYN_RS10780 faa79bcd011f23e2b1d890eacd562616 66 Gene3D G3DSA:3.90.320.10 1 55 2.5E-4 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 THSYN_RS20370 ee915a62c2d6761e77333444554c1de0 235 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 8 229 5.9E-69 T 29-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 THSYN_RS20370 ee915a62c2d6761e77333444554c1de0 235 SUPERFAMILY SSF53448 6 229 2.93E-55 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS20370 ee915a62c2d6761e77333444554c1de0 235 Gene3D G3DSA:3.90.550.10 1 234 1.6E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS20370 ee915a62c2d6761e77333444554c1de0 235 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 7 227 2.6E-69 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 THSYN_RS20370 ee915a62c2d6761e77333444554c1de0 235 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 104 111 - T 29-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 THSYN_RS20370 ee915a62c2d6761e77333444554c1de0 235 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 5 228 42.417 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 THSYN_RS00805 d6c65454f24d5bae30b5da110c0a9aff 79 SUPERFAMILY SSF143880 1 74 2.35E-21 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS00805 d6c65454f24d5bae30b5da110c0a9aff 79 Gene3D G3DSA:3.30.2020.10 1 75 2.3E-24 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS00805 d6c65454f24d5bae30b5da110c0a9aff 79 Pfam PF10387 Protein of unknown function (DUF2442) 4 72 3.2E-18 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 PIRSF PIRSF006288 10 884 0.0 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 SUPERFAMILY SSF81593 195 313 4.71E-9 T 29-03-2018 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 Pfam PF01966 HD domain 459 590 3.1E-10 T 29-03-2018 IPR006674 HD domain THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 889 309.031 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 SUPERFAMILY SSF81301 15 170 2.66E-22 T 29-03-2018 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 Gene3D G3DSA:3.30.70.260 802 880 8.8E-8 T 29-03-2018 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 Gene3D G3DSA:3.30.70.260 693 782 4.0E-5 T 29-03-2018 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 SUPERFAMILY SSF109604 425 587 2.39E-12 T 29-03-2018 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 Gene3D G3DSA:3.30.460.10 19 172 7.3E-23 T 29-03-2018 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 Pfam PF08335 GlnD PII-uridylyltransferase 182 321 3.4E-36 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 Gene3D G3DSA:1.20.120.330 174 323 9.3E-25 T 29-03-2018 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 SMART SM00471 454 601 9.2E-8 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 34 863 1.0E-276 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 SUPERFAMILY SSF55021 697 768 6.11E-7 T 29-03-2018 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 Pfam PF03445 Putative nucleotidyltransferase DUF294 39 120 4.2E-4 T 29-03-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 SUPERFAMILY SSF55021 805 868 8.4E-7 T 29-03-2018 THSYN_RS22050 63a628b2b0ba4c8fbeb48b5f14dc54b5 889 Gene3D G3DSA:1.10.3090.10 381 638 4.5E-38 T 29-03-2018 THSYN_RS07785 13c8c554dd22d363475999466c3565ec 308 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 84 106 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site THSYN_RS07785 13c8c554dd22d363475999466c3565ec 308 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 28 304 1.1E-99 T 29-03-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 THSYN_RS07785 13c8c554dd22d363475999466c3565ec 308 Pfam PF01040 UbiA prenyltransferase family 45 287 1.5E-62 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 THSYN_RS07785 13c8c554dd22d363475999466c3565ec 308 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 22 305 29.516 T 29-03-2018 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 THSYN_RS09435 f20d8cfab521d4d59c9c288d9db01d00 157 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 108 2.0E-16 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 THSYN_RS09435 f20d8cfab521d4d59c9c288d9db01d00 157 Pfam PF02033 Ribosome-binding factor A 6 121 1.4E-25 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 THSYN_RS09435 f20d8cfab521d4d59c9c288d9db01d00 157 Gene3D G3DSA:3.30.300.20 1 114 3.2E-27 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta THSYN_RS09435 f20d8cfab521d4d59c9c288d9db01d00 157 ProSitePatterns PS01319 Ribosome-binding factor A signature. 87 108 - T 29-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 THSYN_RS09435 f20d8cfab521d4d59c9c288d9db01d00 157 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 5 123 3.3E-22 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 THSYN_RS09435 f20d8cfab521d4d59c9c288d9db01d00 157 SUPERFAMILY SSF89919 3 123 1.57E-24 T 29-03-2018 IPR023799 Ribosome-binding factor A domain THSYN_RS09435 f20d8cfab521d4d59c9c288d9db01d00 157 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 128 18.719 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 Gene3D G3DSA:1.20.120.330 271 372 2.6E-4 T 29-03-2018 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 Gene3D G3DSA:3.40.190.10 180 270 3.0E-7 T 29-03-2018 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 Gene3D G3DSA:3.40.50.2300 763 924 4.7E-30 T 29-03-2018 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 66 280 2.6E-32 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 Gene3D G3DSA:3.30.450.20 373 511 1.1E-30 T 29-03-2018 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 Gene3D G3DSA:3.30.565.10 580 742 9.1E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 PRINTS PR00344 Bacterial sensor protein C-terminal signature 686 696 3.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 PRINTS PR00344 Bacterial sensor protein C-terminal signature 702 720 3.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 PRINTS PR00344 Bacterial sensor protein C-terminal signature 668 682 3.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 PRINTS PR00344 Bacterial sensor protein C-terminal signature 726 739 3.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 SMART SM00387 631 742 2.9E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 SUPERFAMILY SSF47384 504 586 2.35E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 Gene3D G3DSA:3.40.190.10 57 179 5.0E-17 T 29-03-2018 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 SMART SM00388 519 585 1.1E-26 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 SMART SM00062 62 283 5.3E-17 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 SUPERFAMILY SSF55874 574 739 2.88E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 SUPERFAMILY SSF53850 63 282 1.27E-40 T 29-03-2018 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 631 740 1.9E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 Pfam PF00072 Response regulator receiver domain 769 889 1.8E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 Gene3D G3DSA:1.10.287.130 512 579 7.3E-21 T 29-03-2018 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 375 506 4.0E-19 T 29-03-2018 IPR000014 PAS domain THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 SUPERFAMILY SSF52172 768 897 1.85E-28 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 SUPERFAMILY SSF55785 366 496 2.74E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 SMART SM00448 767 889 1.1E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 SMART SM00091 379 445 1.6E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 Pfam PF00512 His Kinase A (phospho-acceptor) domain 519 585 7.9E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 SMART SM00086 457 499 3.1E-6 T 29-03-2018 IPR001610 PAC motif THSYN_RS27155 9531ae6567864da13e05a792561e2e87 996 Pfam PF00989 PAS fold 382 496 5.2E-12 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SUPERFAMILY SSF55785 437 571 2.09E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Gene3D G3DSA:3.40.50.2300 1136 1271 3.3E-33 T 29-03-2018 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SUPERFAMILY SSF47226 938 950 1.24E-16 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SUPERFAMILY SSF47226 990 1078 1.24E-16 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SMART SM00388 586 651 2.0E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1283 1441 1.4E-46 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SMART SM00073 1000 1097 6.8E-4 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Gene3D G3DSA:3.30.450.20 381 446 2.6E-10 T 29-03-2018 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SMART SM00267 1272 1445 2.3E-58 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SMART SM00448 1146 1259 1.9E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SMART SM00448 839 954 5.6E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Pfam PF13188 PAS domain 69 106 1.8E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Pfam PF13188 PAS domain 452 516 1.9E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Pfam PF08447 PAS fold 219 305 1.7E-19 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SUPERFAMILY SSF47384 572 652 3.14E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SUPERFAMILY SSF55785 59 182 2.09E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 587 651 1.5E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Gene3D G3DSA:3.40.50.2300 827 961 6.1E-39 T 29-03-2018 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Pfam PF01627 Hpt domain 1013 1094 2.5E-9 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SUPERFAMILY SSF52172 1141 1277 1.85E-34 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Gene3D G3DSA:3.30.565.10 655 822 6.6E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SUPERFAMILY SSF52172 837 959 2.99E-37 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SUPERFAMILY SSF55785 309 438 1.2E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Gene3D G3DSA:1.10.287.130 587 647 1.9E-19 T 29-03-2018 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SMART SM00086 270 312 0.0018 T 29-03-2018 IPR001610 PAC motif THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SMART SM00086 398 440 0.97 T 29-03-2018 IPR001610 PAC motif THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SMART SM00086 146 184 430.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Pfam PF00072 Response regulator receiver domain 842 954 1.0E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Pfam PF00072 Response regulator receiver domain 1148 1258 4.6E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SUPERFAMILY SSF55785 182 310 1.38E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Gene3D G3DSA:1.20.120.160 1001 1132 1.4E-14 T 29-03-2018 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SUPERFAMILY SSF55073 1288 1446 2.12E-47 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 244 319 1.5E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 448 579 8.4E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 698 813 1.7E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1280 1444 1.8E-41 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Gene3D G3DSA:3.30.450.20 335 380 2.8E-13 T 29-03-2018 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Gene3D G3DSA:3.30.450.20 180 334 2.4E-30 T 29-03-2018 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Gene3D G3DSA:3.30.450.20 28 179 6.7E-17 T 29-03-2018 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Gene3D G3DSA:3.30.450.20 447 586 6.1E-27 T 29-03-2018 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SUPERFAMILY SSF55874 640 816 9.69E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SMART SM00387 698 814 1.4E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 798 811 9.6E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 774 792 9.6E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 739 753 9.6E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Pfam PF13426 PAS domain 381 439 0.42 T 29-03-2018 IPR000014 PAS domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SMART SM00091 324 392 130.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SMART SM00091 452 521 3.3E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SMART SM00091 67 137 0.0022 T 29-03-2018 IPR000014 PAS domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 SMART SM00091 196 264 3.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS08180 da4a986375434db2211c48f3e81c2389 1453 Gene3D G3DSA:3.30.70.270 1272 1446 5.2E-55 T 29-03-2018 THSYN_RS23170 c5cb3a4c6a77c1374d9611dcf5507c8e 531 Gene3D G3DSA:3.40.50.980 181 325 1.2E-33 T 29-03-2018 THSYN_RS23170 c5cb3a4c6a77c1374d9611dcf5507c8e 531 Gene3D G3DSA:3.30.300.30 405 505 2.4E-21 T 29-03-2018 THSYN_RS23170 c5cb3a4c6a77c1374d9611dcf5507c8e 531 Gene3D G3DSA:3.40.50.980 40 180 2.2E-12 T 29-03-2018 THSYN_RS23170 c5cb3a4c6a77c1374d9611dcf5507c8e 531 Pfam PF13193 AMP-binding enzyme C-terminal domain 420 490 1.8E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain THSYN_RS23170 c5cb3a4c6a77c1374d9611dcf5507c8e 531 SUPERFAMILY SSF56801 55 502 9.16E-91 T 29-03-2018 THSYN_RS23170 c5cb3a4c6a77c1374d9611dcf5507c8e 531 Gene3D G3DSA:2.30.38.10 326 404 8.1E-8 T 29-03-2018 THSYN_RS23170 c5cb3a4c6a77c1374d9611dcf5507c8e 531 Pfam PF00501 AMP-binding enzyme 59 410 8.9E-41 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THSYN_RS16835 5b814ad3ca2a285f28200e053f4e896a 371 Gene3D G3DSA:3.40.50.2000 186 349 1.9E-39 T 29-03-2018 THSYN_RS16835 5b814ad3ca2a285f28200e053f4e896a 371 Gene3D G3DSA:3.40.50.2000 4 185 4.0E-10 T 29-03-2018 THSYN_RS16835 5b814ad3ca2a285f28200e053f4e896a 371 Pfam PF13439 Glycosyltransferase Family 4 17 176 3.1E-9 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS16835 5b814ad3ca2a285f28200e053f4e896a 371 Pfam PF00534 Glycosyl transferases group 1 198 349 1.6E-31 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS16835 5b814ad3ca2a285f28200e053f4e896a 371 SUPERFAMILY SSF53756 5 362 6.73E-66 T 29-03-2018 THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 929 1010 7.6E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 3126 3226 3.4E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 2572 2665 2.4E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 2189 2283 2.2E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 256 344 1.4E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 1011 1105 6.2E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 3420 3506 4.5E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 3705 3797 1.9E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF49299 3033 3123 1.24E-9 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF69318 754 914 8.63E-23 T 29-03-2018 THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:3.40.1850.10 3250 3330 2.7E-16 T 29-03-2018 THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:3.40.1850.10 3617 3704 2.0E-15 T 29-03-2018 THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.130.10.130 801 928 9.8E-9 T 29-03-2018 THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF49299 3521 3606 7.32E-8 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF49299 2576 2660 1.1E-8 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF49299 3242 3327 1.7E-8 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF49299 262 344 6.02E-13 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 2284 2566 1.0E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF49313 349 439 7.22E-10 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.120.560 1157 1318 1.4E-25 T 29-03-2018 THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 3608 3698 1.7 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 3423 3510 0.089 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 2194 2283 2.6E-9 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 1768 1836 0.33 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 2116 2190 8.1 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 1012 1102 4.6E-7 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 266 345 3.3E-14 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 1840 1927 2.0E-11 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 3517 3607 0.38 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 3329 3420 1.9 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 3244 3328 1.4E-6 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 2566 2662 2.3E-4 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 3705 3794 8.1E-4 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 3034 3125 0.19 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SMART SM00089 922 1009 1.7E-15 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 3331 3419 3.6E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 3507 3606 1.7E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Pfam PF00801 PKD domain 273 335 3.0E-8 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Pfam PF00801 PKD domain 2585 2650 2.0E-6 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Pfam PF00801 PKD domain 1860 1914 3.2E-10 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Pfam PF00801 PKD domain 3040 3111 1.7E-5 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Pfam PF00801 PKD domain 1039 1091 6.3E-6 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Pfam PF00801 PKD domain 936 993 4.4E-13 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 1786 1837 4.2E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 1838 1933 5.2E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 345 437 1.1E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 3799 3887 3.4E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF69318 442 588 4.84E-14 T 29-03-2018 THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.120.260 577 742 1.6E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF49299 3421 3510 9.29E-8 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF49299 2158 2281 1.96E-12 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 1407 1463 0.45 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 3041 3125 5.6E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF49299 3327 3419 1.1E-7 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF49299 1039 1100 9.55E-12 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 767 828 1.3E-9 T 29-03-2018 THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF49299 1860 1926 6.02E-13 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 1950 2188 3.2E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Pfam PF06439 Domain of Unknown Function (DUF1080) 1162 1330 1.3E-6 T 29-03-2018 IPR010496 Domain of unknown function DUF1080 THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF49299 3686 3793 1.83E-9 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 SUPERFAMILY SSF49299 908 1010 2.09E-17 T 29-03-2018 IPR000601 PKD domain THSYN_RS15075 f8fda05cbe55ebbe3e03db7e509b14d9 3891 Gene3D G3DSA:2.60.40.10 1319 1381 0.21 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS31790 b4a132c1307c77c66c8a1869359e3156 633 SUPERFAMILY SSF53335 82 135 1.19E-68 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS31790 b4a132c1307c77c66c8a1869359e3156 633 SUPERFAMILY SSF53335 166 301 1.19E-68 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS31790 b4a132c1307c77c66c8a1869359e3156 633 SUPERFAMILY SSF53335 356 460 1.19E-68 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS31790 b4a132c1307c77c66c8a1869359e3156 633 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 384 406 2.3E-15 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS31790 b4a132c1307c77c66c8a1869359e3156 633 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 178 197 2.3E-15 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS31790 b4a132c1307c77c66c8a1869359e3156 633 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 407 421 2.3E-15 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS31790 b4a132c1307c77c66c8a1869359e3156 633 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 115 127 2.3E-15 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS31790 b4a132c1307c77c66c8a1869359e3156 633 Pfam PF01555 DNA methylase 115 427 3.6E-38 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THSYN_RS31790 b4a132c1307c77c66c8a1869359e3156 633 PIRSF PIRSF015855 5 632 2.0E-169 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS31790 b4a132c1307c77c66c8a1869359e3156 633 Gene3D G3DSA:3.40.50.150 92 475 4.6E-52 T 29-03-2018 THSYN_RS31790 b4a132c1307c77c66c8a1869359e3156 633 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 118 124 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS02840 953ae1446e1af2466bc2affb370e8e05 168 Gene3D G3DSA:1.20.1260.10 104 167 5.3E-7 T 29-03-2018 IPR012347 Ferritin-related THSYN_RS02840 953ae1446e1af2466bc2affb370e8e05 168 Gene3D G3DSA:1.20.1260.10 2 75 1.8E-7 T 29-03-2018 IPR012347 Ferritin-related THSYN_RS02840 953ae1446e1af2466bc2affb370e8e05 168 SUPERFAMILY SSF47240 17 81 1.81E-8 T 29-03-2018 IPR009078 Ferritin-like superfamily THSYN_RS02840 953ae1446e1af2466bc2affb370e8e05 168 SUPERFAMILY SSF47240 109 165 2.72E-10 T 29-03-2018 IPR009078 Ferritin-like superfamily THSYN_RS16300 db633eb7ede709e0eb4cc32fa2fa288b 107 Gene3D G3DSA:1.10.260.40 23 105 2.6E-5 T 29-03-2018 THSYN_RS16300 db633eb7ede709e0eb4cc32fa2fa288b 107 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 10 96 9.1E-38 T 29-03-2018 IPR014057 Addiction module antidote protein, HI1420 THSYN_RS16300 db633eb7ede709e0eb4cc32fa2fa288b 107 SUPERFAMILY SSF47413 32 94 1.8E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS23750 c4bfb3e47ff22f49a134d597396fa598 106 Gene3D G3DSA:3.40.50.300 59 104 1.1E-4 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1233 1243 4.0E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1215 1229 4.0E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1250 1268 4.0E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1274 1287 4.0E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1061 1126 3.9E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00086 852 894 2.9 T 29-03-2018 IPR001610 PAC motif THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00086 475 517 4.9E-7 T 29-03-2018 IPR001610 PAC motif THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00086 1003 1041 180.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00086 360 402 2.4E-6 T 29-03-2018 IPR001610 PAC motif THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00086 731 773 1.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00086 600 640 11.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF47384 1047 1127 9.42E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF47226 1613 1705 3.01E-11 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF47226 1555 1568 3.01E-11 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 408 524 3.4E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 920 1048 1.4E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 656 780 7.0E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 780 901 1.5E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 287 402 1.7E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 525 643 2.6E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF01627 Hpt domain 1634 1711 2.8E-6 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF52172 1303 1437 1.28E-19 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00387 1174 1290 1.6E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF55874 1115 1292 5.24E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Gene3D G3DSA:3.40.50.2300 1293 1439 7.3E-21 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00091 924 994 1.4 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00091 403 470 1.8E-4 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00091 529 595 1.8E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00091 285 353 4.7E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00091 781 847 8.0E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00091 660 725 0.013 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Gene3D G3DSA:3.10.580.10 1 127 1.1E-18 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Gene3D G3DSA:3.30.450.20 652 781 3.2E-27 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Gene3D G3DSA:3.30.450.20 918 1055 1.4E-23 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Gene3D G3DSA:3.30.450.20 282 407 3.0E-25 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF13426 PAS domain 540 639 1.8E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF13426 PAS domain 295 401 5.5E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF13426 PAS domain 416 515 7.2E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Gene3D G3DSA:3.30.565.10 1131 1292 4.0E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF54631 14 126 2.78E-19 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF55785 278 400 1.19E-23 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00448 1304 1428 1.1E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00448 1457 1572 5.6E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Gene3D G3DSA:3.40.50.2300 1445 1587 2.1E-37 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Gene3D G3DSA:1.10.287.130 1056 1122 6.1E-17 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Gene3D G3DSA:3.30.450.20 520 651 1.1E-28 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF55785 514 638 2.44E-24 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Gene3D G3DSA:3.30.450.20 408 519 4.5E-24 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00388 1061 1126 2.5E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF55785 770 892 2.09E-20 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Gene3D G3DSA:3.30.450.20 782 917 3.5E-26 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF13188 PAS domain 925 965 4.8E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF54631 135 253 4.17E-31 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF00571 CBS domain 73 126 5.4E-6 T 29-03-2018 IPR000644 CBS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF00571 CBS domain 201 255 3.5E-8 T 29-03-2018 IPR000644 CBS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF00571 CBS domain 137 189 1.0E-10 T 29-03-2018 IPR000644 CBS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF55785 666 776 6.88E-19 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF55785 916 1039 7.68E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Gene3D G3DSA:3.10.580.10 129 281 3.0E-31 T 29-03-2018 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF00072 Response regulator receiver domain 1307 1428 2.2E-9 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF00072 Response regulator receiver domain 1459 1572 2.0E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF08448 PAS fold 667 775 1.4E-15 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF08448 PAS fold 788 896 6.9E-18 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF55785 424 525 1.33E-19 T 29-03-2018 IPR000014 PAS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1174 1288 2.0E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SUPERFAMILY SSF52172 1455 1582 1.71E-37 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00116 144 191 8.9E-9 T 29-03-2018 IPR000644 CBS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00116 208 256 2.4E-4 T 29-03-2018 IPR000644 CBS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00116 79 127 3.9E-5 T 29-03-2018 IPR000644 CBS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 SMART SM00116 15 62 0.031 T 29-03-2018 IPR000644 CBS domain THSYN_RS19350 98f32d6356a1761c935532f96d7be94c 1802 Gene3D G3DSA:1.20.120.160 1626 1776 8.5E-10 T 29-03-2018 THSYN_RS09580 aec8440f159cade673db244bd1811c41 684 Gene3D G3DSA:1.50.10.10 232 376 9.4E-30 T 29-03-2018 THSYN_RS09580 aec8440f159cade673db244bd1811c41 684 Gene3D G3DSA:1.50.10.10 377 640 3.6E-28 T 29-03-2018 THSYN_RS09580 aec8440f159cade673db244bd1811c41 684 Gene3D G3DSA:3.40.30.10 8 179 4.6E-24 T 29-03-2018 THSYN_RS09580 aec8440f159cade673db244bd1811c41 684 SUPERFAMILY SSF52833 8 139 4.56E-28 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS09580 aec8440f159cade673db244bd1811c41 684 SUPERFAMILY SSF48208 190 550 1.02E-69 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 THSYN_RS09580 aec8440f159cade673db244bd1811c41 684 Pfam PF03190 Protein of unknown function, DUF255 11 173 7.6E-71 T 29-03-2018 IPR004879 Domain of unknown function DUF255 THSYN_RS09580 aec8440f159cade673db244bd1811c41 684 PIRSF PIRSF006402 1 684 2.1E-207 T 29-03-2018 IPR024705 Spermatogenesis-associated protein 20 THSYN_RS11695 8c446c6f40a2bfcca30c400c6b290064 149 ProDom PD005668 HYDROGENASE HUPH HYDROGENASE-1 EXPRESSION/FORMATION OPERON PROTEIN C-TERMINAL EXPRESSION HYAF HOXQ 26 132 3.0E-14 T 29-03-2018 IPR006894 HupH hydrogenase expression protein, C-terminal THSYN_RS11695 8c446c6f40a2bfcca30c400c6b290064 149 Pfam PF04809 HupH hydrogenase expression protein, C-terminal conserved region 25 136 3.4E-20 T 29-03-2018 IPR006894 HupH hydrogenase expression protein, C-terminal THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 Gene3D G3DSA:3.30.565.10 271 425 1.6E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 Pfam PF13188 PAS domain 92 138 2.5E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 SUPERFAMILY SSF55874 256 421 2.49E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 SUPERFAMILY SSF55785 88 193 1.69E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 Gene3D G3DSA:1.10.287.130 194 263 2.6E-18 T 29-03-2018 THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 91 419 7.7E-124 T 29-03-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 Gene3D G3DSA:3.30.450.20 88 193 1.3E-11 T 29-03-2018 THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 SMART SM00388 201 267 3.1E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 SMART SM00387 311 423 3.5E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 Pfam PF00512 His Kinase A (phospho-acceptor) domain 202 265 2.1E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 Pfam PF11808 Domain of unknown function (DUF3329) 7 85 1.2E-14 T 29-03-2018 IPR021766 Protein of unknown function DUF3329 GO:0004673 THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 421 3.7E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 362 5.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 401 5.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 420 5.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 376 5.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 SUPERFAMILY SSF47384 188 267 3.34E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10355 89a1fe9237e24ac759b866345ebf248c 438 SMART SM00091 92 158 9.9E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS16780 b250ee76c72ab0aadb5ea6b35d5200b9 107 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 32 75 6.3E-12 T 29-03-2018 IPR022453 Zinc finger, MqsA-type THSYN_RS07275 1c5f4a158941a472c0d60fb55e01da78 385 Gene3D G3DSA:1.10.10.10 24 80 0.0072 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07275 1c5f4a158941a472c0d60fb55e01da78 385 Pfam PF13592 Winged helix-turn helix 133 186 2.0E-13 T 29-03-2018 IPR025959 Winged helix-turn helix domain THSYN_RS07275 1c5f4a158941a472c0d60fb55e01da78 385 Gene3D G3DSA:3.30.420.10 226 373 6.2E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS07275 1c5f4a158941a472c0d60fb55e01da78 385 Pfam PF13358 DDE superfamily endonuclease 204 346 2.1E-22 T 29-03-2018 THSYN_RS28615 1c5f4a158941a472c0d60fb55e01da78 385 Gene3D G3DSA:1.10.10.10 24 80 0.0072 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS28615 1c5f4a158941a472c0d60fb55e01da78 385 Pfam PF13592 Winged helix-turn helix 133 186 2.0E-13 T 29-03-2018 IPR025959 Winged helix-turn helix domain THSYN_RS28615 1c5f4a158941a472c0d60fb55e01da78 385 Gene3D G3DSA:3.30.420.10 226 373 6.2E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS28615 1c5f4a158941a472c0d60fb55e01da78 385 Pfam PF13358 DDE superfamily endonuclease 204 346 2.1E-22 T 29-03-2018 THSYN_RS17610 1c5f4a158941a472c0d60fb55e01da78 385 Gene3D G3DSA:1.10.10.10 24 80 0.0072 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS17610 1c5f4a158941a472c0d60fb55e01da78 385 Pfam PF13592 Winged helix-turn helix 133 186 2.0E-13 T 29-03-2018 IPR025959 Winged helix-turn helix domain THSYN_RS17610 1c5f4a158941a472c0d60fb55e01da78 385 Gene3D G3DSA:3.30.420.10 226 373 6.2E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS17610 1c5f4a158941a472c0d60fb55e01da78 385 Pfam PF13358 DDE superfamily endonuclease 204 346 2.1E-22 T 29-03-2018 THSYN_RS00775 f3b32ff65f99478cf7c0c78de25ab620 982 Gene3D G3DSA:3.40.50.300 193 370 8.0E-26 T 29-03-2018 THSYN_RS00775 f3b32ff65f99478cf7c0c78de25ab620 982 Gene3D G3DSA:2.10.109.10 838 966 3.9E-8 T 29-03-2018 THSYN_RS00775 f3b32ff65f99478cf7c0c78de25ab620 982 Pfam PF00271 Helicase conserved C-terminal domain 429 525 1.4E-9 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS00775 f3b32ff65f99478cf7c0c78de25ab620 982 SUPERFAMILY SSF52540 253 392 1.33E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00775 f3b32ff65f99478cf7c0c78de25ab620 982 SUPERFAMILY SSF52540 420 541 1.33E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00775 f3b32ff65f99478cf7c0c78de25ab620 982 Gene3D G3DSA:3.30.870.10 11 188 3.2E-12 T 29-03-2018 THSYN_RS00775 f3b32ff65f99478cf7c0c78de25ab620 982 Pfam PF04851 Type III restriction enzyme, res subunit 206 352 3.0E-29 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS00775 f3b32ff65f99478cf7c0c78de25ab620 982 Gene3D G3DSA:3.40.50.300 415 737 6.3E-21 T 29-03-2018 THSYN_RS00775 f3b32ff65f99478cf7c0c78de25ab620 982 SUPERFAMILY SSF51306 830 952 6.63E-8 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THSYN_RS00775 f3b32ff65f99478cf7c0c78de25ab620 982 SUPERFAMILY SSF56024 7 140 5.65E-7 T 29-03-2018 THSYN_RS00775 f3b32ff65f99478cf7c0c78de25ab620 982 SMART SM00487 200 379 1.2E-17 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS00775 f3b32ff65f99478cf7c0c78de25ab620 982 Pfam PF13091 PLD-like domain 20 140 9.0E-13 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THSYN_RS00775 f3b32ff65f99478cf7c0c78de25ab620 982 SMART SM00490 447 527 3.0E-9 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS04065 c3a0d0123fa211fe7f7b89d822dc1ea3 103 Gene3D G3DSA:3.30.110.60 6 100 5.8E-24 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 THSYN_RS04065 c3a0d0123fa211fe7f7b89d822dc1ea3 103 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 8 92 1.6E-24 T 29-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 THSYN_RS04065 c3a0d0123fa211fe7f7b89d822dc1ea3 103 Pfam PF01985 CRS1 / YhbY (CRM) domain 8 90 1.7E-20 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 THSYN_RS04065 c3a0d0123fa211fe7f7b89d822dc1ea3 103 SMART SM01103 7 90 8.4E-36 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 THSYN_RS04065 c3a0d0123fa211fe7f7b89d822dc1ea3 103 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 13 95 5.0E-14 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 THSYN_RS04065 c3a0d0123fa211fe7f7b89d822dc1ea3 103 SUPERFAMILY SSF75471 6 97 8.11E-28 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 THSYN_RS02995 10a0c8729740a9eb2a9b133a3e36cef7 273 Gene3D G3DSA:3.40.1130.10 63 264 4.6E-18 T 29-03-2018 THSYN_RS02995 10a0c8729740a9eb2a9b133a3e36cef7 273 Pfam PF01553 Acyltransferase 92 205 8.8E-8 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THSYN_RS02995 10a0c8729740a9eb2a9b133a3e36cef7 273 SMART SM00563 104 212 2.9E-9 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THSYN_RS02995 10a0c8729740a9eb2a9b133a3e36cef7 273 SUPERFAMILY SSF69593 25 254 4.84E-17 T 29-03-2018 THSYN_RS10900 7e9b27213d16042957c1bd05db623a35 1052 Gene3D G3DSA:1.25.40.10 643 1051 4.7E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS10900 7e9b27213d16042957c1bd05db623a35 1052 SUPERFAMILY SSF48452 659 736 4.09E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS10900 7e9b27213d16042957c1bd05db623a35 1052 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 227 292 2.0E-15 T 29-03-2018 IPR020012 Motility protein FimV, N-terminal THSYN_RS10900 7e9b27213d16042957c1bd05db623a35 1052 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 1008 1050 1.1E-18 T 29-03-2018 IPR020011 Motility protein FimV, C-terminal THSYN_RS13075 074efa458ec9092f9fe686daccc67b01 404 Gene3D G3DSA:3.40.50.620 7 277 1.4E-70 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS13075 074efa458ec9092f9fe686daccc67b01 404 Pfam PF00579 tRNA synthetases class I (W and Y) 7 175 7.6E-50 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS13075 074efa458ec9092f9fe686daccc67b01 404 Pfam PF00579 tRNA synthetases class I (W and Y) 249 313 3.8E-9 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS13075 074efa458ec9092f9fe686daccc67b01 404 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 8 181 5.7E-57 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 THSYN_RS13075 074efa458ec9092f9fe686daccc67b01 404 SUPERFAMILY SSF52374 10 177 1.64E-85 T 29-03-2018 THSYN_RS13075 074efa458ec9092f9fe686daccc67b01 404 SUPERFAMILY SSF52374 248 402 1.64E-85 T 29-03-2018 THSYN_RS13075 074efa458ec9092f9fe686daccc67b01 404 Gene3D G3DSA:1.10.240.10 278 398 5.5E-28 T 29-03-2018 THSYN_RS13075 074efa458ec9092f9fe686daccc67b01 404 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 150 171 3.9E-20 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 THSYN_RS13075 074efa458ec9092f9fe686daccc67b01 404 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 72 91 3.9E-20 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 THSYN_RS13075 074efa458ec9092f9fe686daccc67b01 404 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 21 37 3.9E-20 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 THSYN_RS13075 074efa458ec9092f9fe686daccc67b01 404 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 26 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 SUPERFAMILY SSF52540 147 389 3.68E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 361 370 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 Gene3D G3DSA:1.10.8.60 321 405 3.8E-23 T 29-03-2018 THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 Gene3D G3DSA:1.10.10.60 406 451 2.5E-16 T 29-03-2018 THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 SUPERFAMILY SSF52172 5 192 3.84E-28 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 Gene3D G3DSA:3.40.50.2300 1 144 3.2E-19 T 29-03-2018 THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 SMART SM00448 6 120 4.2E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 TIGRFAM TIGR02915 PEP_resp_reg: PEP-CTERM-box response regulator transcription factor 8 449 1.5E-211 T 29-03-2018 IPR014264 Signal transduction response regulator, PEP-CTERM system, putative THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 430 450 8.7E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 413 430 8.7E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 Pfam PF00072 Response regulator receiver domain 9 120 2.3E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 Gene3D G3DSA:3.40.50.300 145 320 9.3E-27 T 29-03-2018 THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 Pfam PF00158 Sigma-54 interaction domain 148 314 5.3E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 Pfam PF02954 Bacterial regulatory protein, Fis family 408 447 2.4E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 SMART SM00382 168 311 3.6E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS01950 d06d9a3b882a136453ca35ab87249e74 451 SUPERFAMILY SSF46689 361 449 6.09E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS31680 ac3c2e8fce8bef0ca3176edee8385b02 303 PIRSF PIRSF000363 36 303 4.6E-104 T 29-03-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 THSYN_RS31680 ac3c2e8fce8bef0ca3176edee8385b02 303 TIGRFAM TIGR01281 DPOR_bchL: light-independent protochlorophyllide reductase, iron-sulfur ATP-binding protein 38 301 5.7E-133 T 29-03-2018 IPR005971 Light-independent protochlorophyllide reductase, iron-sulphur ATP-binding protein GO:0005524|GO:0015995|GO:0016730|GO:0019685|GO:0046148|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31680 ac3c2e8fce8bef0ca3176edee8385b02 303 Hamap MF_00355 Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein [bchL]. 38 303 52.92 T 29-03-2018 IPR005971 Light-independent protochlorophyllide reductase, iron-sulphur ATP-binding protein GO:0005524|GO:0015995|GO:0016730|GO:0019685|GO:0046148|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31680 ac3c2e8fce8bef0ca3176edee8385b02 303 ProSitePatterns PS00746 NifH/frxC family signature 1. 122 134 - T 29-03-2018 IPR030655 NifH/chlL conserved site THSYN_RS31680 ac3c2e8fce8bef0ca3176edee8385b02 303 Gene3D G3DSA:3.40.50.300 36 303 8.2E-44 T 29-03-2018 THSYN_RS31680 ac3c2e8fce8bef0ca3176edee8385b02 303 PRINTS PR00091 Nitrogenase component II signature 120 134 3.0E-32 T 29-03-2018 THSYN_RS31680 ac3c2e8fce8bef0ca3176edee8385b02 303 PRINTS PR00091 Nitrogenase component II signature 65 80 3.0E-32 T 29-03-2018 THSYN_RS31680 ac3c2e8fce8bef0ca3176edee8385b02 303 PRINTS PR00091 Nitrogenase component II signature 158 173 3.0E-32 T 29-03-2018 THSYN_RS31680 ac3c2e8fce8bef0ca3176edee8385b02 303 PRINTS PR00091 Nitrogenase component II signature 43 56 3.0E-32 T 29-03-2018 THSYN_RS31680 ac3c2e8fce8bef0ca3176edee8385b02 303 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 39 300 7.1E-86 T 29-03-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 THSYN_RS31680 ac3c2e8fce8bef0ca3176edee8385b02 303 ProSitePatterns PS00692 NifH/frxC family signature 2. 159 172 - T 29-03-2018 IPR030655 NifH/chlL conserved site THSYN_RS31680 ac3c2e8fce8bef0ca3176edee8385b02 303 SUPERFAMILY SSF52540 37 299 4.71E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19770 131b641249bf26c08bfe647a618e5d85 187 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 1 175 3.2E-52 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 THSYN_RS19770 131b641249bf26c08bfe647a618e5d85 187 SUPERFAMILY SSF53335 1 173 5.72E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS19770 131b641249bf26c08bfe647a618e5d85 187 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 113 119 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS19770 131b641249bf26c08bfe647a618e5d85 187 Pfam PF03602 Conserved hypothetical protein 95 1 173 6.0E-56 T 29-03-2018 THSYN_RS19770 131b641249bf26c08bfe647a618e5d85 187 Gene3D G3DSA:3.40.50.150 1 179 2.5E-39 T 29-03-2018 THSYN_RS19770 131b641249bf26c08bfe647a618e5d85 187 PIRSF PIRSF004553 1 179 7.4E-52 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 THSYN_RS28290 cc650e1cf492373b27fa049d492e565e 293 SUPERFAMILY SSF103481 196 292 7.98E-7 T 29-03-2018 THSYN_RS28290 cc650e1cf492373b27fa049d492e565e 293 Pfam PF00892 EamA-like transporter family 4 134 1.8E-11 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 THSYN_RS28290 cc650e1cf492373b27fa049d492e565e 293 Pfam PF00892 EamA-like transporter family 158 290 5.7E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 THSYN_RS28290 cc650e1cf492373b27fa049d492e565e 293 SUPERFAMILY SSF103481 37 137 4.45E-12 T 29-03-2018 THSYN_RS03640 c04ce16452a1bbf35875ae86316cbfe8 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 130 11.198 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS03640 c04ce16452a1bbf35875ae86316cbfe8 133 Gene3D G3DSA:3.40.50.1010 2 133 2.0E-27 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS03640 c04ce16452a1bbf35875ae86316cbfe8 133 SUPERFAMILY SSF88723 5 124 2.8E-21 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS03640 c04ce16452a1bbf35875ae86316cbfe8 133 Pfam PF01850 PIN domain 6 123 6.4E-22 T 29-03-2018 IPR002716 PIN domain THSYN_RS13055 28b850973be18fdd0b3bd18c8b0c1b6c 278 TIGRFAM TIGR00637 ModE_repress: ModE molybdate transport repressor domain 32 118 6.6E-30 T 29-03-2018 IPR003725 Molybdenum-binding protein ModE, N-terminal THSYN_RS13055 28b850973be18fdd0b3bd18c8b0c1b6c 278 Gene3D G3DSA:2.40.50.100 201 267 8.0E-11 T 29-03-2018 THSYN_RS13055 28b850973be18fdd0b3bd18c8b0c1b6c 278 PIRSF PIRSF005763 16 278 1.2E-87 T 29-03-2018 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 THSYN_RS13055 28b850973be18fdd0b3bd18c8b0c1b6c 278 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 36 98 3.1E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS13055 28b850973be18fdd0b3bd18c8b0c1b6c 278 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 137 204 2.6E-21 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 THSYN_RS13055 28b850973be18fdd0b3bd18c8b0c1b6c 278 Pfam PF03459 TOBE domain 139 200 1.6E-17 T 29-03-2018 IPR005116 Transport-associated OB, type 1 THSYN_RS13055 28b850973be18fdd0b3bd18c8b0c1b6c 278 SUPERFAMILY SSF50331 137 205 6.56E-20 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal THSYN_RS13055 28b850973be18fdd0b3bd18c8b0c1b6c 278 Gene3D G3DSA:2.40.50.100 136 200 2.9E-23 T 29-03-2018 THSYN_RS13055 28b850973be18fdd0b3bd18c8b0c1b6c 278 SUPERFAMILY SSF46785 20 142 2.63E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS13055 28b850973be18fdd0b3bd18c8b0c1b6c 278 Gene3D G3DSA:1.10.10.10 14 122 4.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS13055 28b850973be18fdd0b3bd18c8b0c1b6c 278 SUPERFAMILY SSF50331 214 277 1.07E-10 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal THSYN_RS17790 01dc5612ca1a2624b8c04d35a80330f7 1394 Pfam PF00271 Helicase conserved C-terminal domain 298 419 6.2E-10 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS17790 01dc5612ca1a2624b8c04d35a80330f7 1394 Gene3D G3DSA:3.40.50.300 85 244 1.1E-29 T 29-03-2018 THSYN_RS17790 01dc5612ca1a2624b8c04d35a80330f7 1394 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 22 621 4.1E-280 T 29-03-2018 IPR010222 RNA helicase HrpA GO:0004004 THSYN_RS17790 01dc5612ca1a2624b8c04d35a80330f7 1394 Gene3D G3DSA:3.40.50.300 267 440 1.2E-45 T 29-03-2018 THSYN_RS17790 01dc5612ca1a2624b8c04d35a80330f7 1394 Pfam PF11898 Domain of unknown function (DUF3418) 778 1390 4.8E-210 T 29-03-2018 IPR024590 RNA helicase HrpA, C-terminal THSYN_RS17790 01dc5612ca1a2624b8c04d35a80330f7 1394 SUPERFAMILY SSF52540 83 604 1.08E-99 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17790 01dc5612ca1a2624b8c04d35a80330f7 1394 SMART SM00490 320 420 1.6E-12 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS17790 01dc5612ca1a2624b8c04d35a80330f7 1394 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 688 761 5.2E-15 T 29-03-2018 IPR011709 Domain of unknown function DUF1605 THSYN_RS17790 01dc5612ca1a2624b8c04d35a80330f7 1394 SMART SM00847 480 570 1.0E-34 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 THSYN_RS17790 01dc5612ca1a2624b8c04d35a80330f7 1394 SMART SM00382 101 400 3.2E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS17790 01dc5612ca1a2624b8c04d35a80330f7 1394 SMART SM00487 84 273 6.2E-23 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS17790 01dc5612ca1a2624b8c04d35a80330f7 1394 Pfam PF04408 Helicase associated domain (HA2) 483 569 1.7E-18 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 THSYN_RS10200 2617779e211f0f03fc6aa21ee4b4fd19 826 Gene3D G3DSA:2.60.40.10 252 343 2.7E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS10200 2617779e211f0f03fc6aa21ee4b4fd19 826 Gene3D G3DSA:2.60.500.10 529 621 8.5E-5 T 29-03-2018 THSYN_RS10200 2617779e211f0f03fc6aa21ee4b4fd19 826 SUPERFAMILY SSF49313 438 524 4.71E-6 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 THSYN_RS10200 2617779e211f0f03fc6aa21ee4b4fd19 826 Gene3D G3DSA:2.60.40.10 432 524 4.9E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS10200 2617779e211f0f03fc6aa21ee4b4fd19 826 Gene3D G3DSA:2.60.40.10 344 431 4.3E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS10200 2617779e211f0f03fc6aa21ee4b4fd19 826 SUPERFAMILY SSF49313 347 436 2.04E-7 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 THSYN_RS10200 2617779e211f0f03fc6aa21ee4b4fd19 826 SUPERFAMILY SSF49299 252 346 3.14E-5 T 29-03-2018 IPR000601 PKD domain THSYN_RS12775 e125b6b934988f9f4a67ba714bee8160 548 Pfam PF00374 Nickel-dependent hydrogenase 230 296 6.6E-9 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THSYN_RS12775 e125b6b934988f9f4a67ba714bee8160 548 Gene3D G3DSA:1.10.645.10 384 534 2.4E-25 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS12775 e125b6b934988f9f4a67ba714bee8160 548 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 305 470 2.6E-33 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS12775 e125b6b934988f9f4a67ba714bee8160 548 SUPERFAMILY SSF143243 80 206 7.19E-20 T 29-03-2018 THSYN_RS12775 e125b6b934988f9f4a67ba714bee8160 548 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 117 169 3.0E-10 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS12775 e125b6b934988f9f4a67ba714bee8160 548 Gene3D G3DSA:1.10.645.10 189 370 3.4E-39 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS12775 e125b6b934988f9f4a67ba714bee8160 548 SUPERFAMILY SSF56762 202 547 3.4E-93 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS12775 e125b6b934988f9f4a67ba714bee8160 548 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 99 170 3.1E-13 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS30665 83e4274f14e04b87a852d5c543fc57a2 158 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 59 9.1E-8 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS30665 83e4274f14e04b87a852d5c543fc57a2 158 SUPERFAMILY SSF54292 2 78 3.28E-24 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS30665 83e4274f14e04b87a852d5c543fc57a2 158 Pfam PF01799 [2Fe-2S] binding domain 73 145 4.5E-28 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 THSYN_RS30665 83e4274f14e04b87a852d5c543fc57a2 158 Gene3D G3DSA:3.10.20.30 1 74 3.0E-26 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS30665 83e4274f14e04b87a852d5c543fc57a2 158 SUPERFAMILY SSF47741 84 153 1.28E-30 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 THSYN_RS30665 83e4274f14e04b87a852d5c543fc57a2 158 Gene3D G3DSA:1.10.150.120 75 158 4.7E-34 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 THSYN_RS30665 83e4274f14e04b87a852d5c543fc57a2 158 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THSYN_RS10300 d973adbcba08bb3094d71d62b5d172d9 331 Gene3D G3DSA:3.20.20.150 10 315 7.3E-14 T 29-03-2018 THSYN_RS10300 d973adbcba08bb3094d71d62b5d172d9 331 ProSitePatterns PS01276 Peptidase family U32 signature. 161 179 - T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 THSYN_RS10300 d973adbcba08bb3094d71d62b5d172d9 331 Pfam PF01136 Peptidase family U32 76 324 2.4E-62 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 THSYN_RS23980 f9f97cd523099f25f71daff7be2229cc 80 SUPERFAMILY SSF143100 5 63 7.19E-10 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS23980 f9f97cd523099f25f71daff7be2229cc 80 Pfam PF08972 Domain of unknown function (DUF1902) 7 75 2.0E-16 T 29-03-2018 IPR015066 Domain of unknown function DUF1902 THSYN_RS23980 f9f97cd523099f25f71daff7be2229cc 80 Gene3D G3DSA:3.30.2390.10 5 75 1.5E-9 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS18890 4277b0b5b2b520f563883a7ee71e8e02 571 Gene3D G3DSA:3.30.420.10 194 355 0.0015 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS10070 4277b0b5b2b520f563883a7ee71e8e02 571 Gene3D G3DSA:3.30.420.10 194 355 0.0015 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS23655 4277b0b5b2b520f563883a7ee71e8e02 571 Gene3D G3DSA:3.30.420.10 194 355 0.0015 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS10235 7ba21c5cdbfa13e597a82973bb38a192 502 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 147 5.8E-27 T 29-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THSYN_RS10235 7ba21c5cdbfa13e597a82973bb38a192 502 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 186 488 1.7E-120 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THSYN_RS10235 7ba21c5cdbfa13e597a82973bb38a192 502 SUPERFAMILY SSF52949 1 184 5.36E-42 T 29-03-2018 THSYN_RS10235 7ba21c5cdbfa13e597a82973bb38a192 502 Gene3D G3DSA:3.40.220.10 1 160 2.0E-34 T 29-03-2018 THSYN_RS10235 7ba21c5cdbfa13e597a82973bb38a192 502 Gene3D G3DSA:3.40.630.10 171 494 1.5E-130 T 29-03-2018 THSYN_RS10235 7ba21c5cdbfa13e597a82973bb38a192 502 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 348 355 - T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THSYN_RS10235 7ba21c5cdbfa13e597a82973bb38a192 502 SUPERFAMILY SSF53187 180 494 3.45E-119 T 29-03-2018 THSYN_RS10235 7ba21c5cdbfa13e597a82973bb38a192 502 PRINTS PR00481 Cytosol aminopeptidase signature 322 343 1.4E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THSYN_RS10235 7ba21c5cdbfa13e597a82973bb38a192 502 PRINTS PR00481 Cytosol aminopeptidase signature 285 306 1.4E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THSYN_RS10235 7ba21c5cdbfa13e597a82973bb38a192 502 PRINTS PR00481 Cytosol aminopeptidase signature 344 364 1.4E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THSYN_RS10235 7ba21c5cdbfa13e597a82973bb38a192 502 PRINTS PR00481 Cytosol aminopeptidase signature 263 280 1.4E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THSYN_RS10235 7ba21c5cdbfa13e597a82973bb38a192 502 PRINTS PR00481 Cytosol aminopeptidase signature 372 387 1.4E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THSYN_RS10235 7ba21c5cdbfa13e597a82973bb38a192 502 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 496 38.046 T 29-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 SUPERFAMILY SSF52172 513 632 3.56E-34 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 372 484 9.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 Pfam PF00672 HAMP domain 174 226 1.4E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 SUPERFAMILY SSF55874 313 483 4.98E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 SUPERFAMILY SSF47384 248 325 1.86E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 SMART SM00304 173 230 1.1E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 Pfam PF00512 His Kinase A (phospho-acceptor) domain 259 324 2.6E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 SMART SM00388 259 324 5.0E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 SMART SM00448 514 628 1.6E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 Gene3D G3DSA:1.10.287.130 249 318 4.5E-19 T 29-03-2018 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 440 1.2E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 426 1.2E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 465 1.2E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 484 1.2E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 SUPERFAMILY SSF158472 190 227 6.93E-6 T 29-03-2018 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 SMART SM00387 371 487 1.2E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 Gene3D G3DSA:3.40.50.2300 507 641 2.7E-36 T 29-03-2018 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 Pfam PF00072 Response regulator receiver domain 516 627 8.8E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS15400 85b0685ef85d0f331ebd5a99f2563075 648 Gene3D G3DSA:3.30.565.10 319 487 7.0E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14265 22fb0ef9817c5e9b467f07801c78f4a9 236 Gene3D G3DSA:1.10.8.60 178 236 2.9E-17 T 29-03-2018 THSYN_RS14265 22fb0ef9817c5e9b467f07801c78f4a9 236 SUPERFAMILY SSF52540 71 235 1.88E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14265 22fb0ef9817c5e9b467f07801c78f4a9 236 Pfam PF00158 Sigma-54 interaction domain 72 171 6.9E-38 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THSYN_RS14265 22fb0ef9817c5e9b467f07801c78f4a9 236 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 218 227 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site THSYN_RS14265 22fb0ef9817c5e9b467f07801c78f4a9 236 Gene3D G3DSA:3.40.50.300 12 177 1.4E-17 T 29-03-2018 THSYN_RS15140 ef70002b16be6d1f6d7beaa58423e582 438 Gene3D G3DSA:1.10.260.40 10 75 1.4E-4 T 29-03-2018 THSYN_RS15140 ef70002b16be6d1f6d7beaa58423e582 438 Gene3D G3DSA:3.40.50.300 107 281 3.9E-8 T 29-03-2018 THSYN_RS15140 ef70002b16be6d1f6d7beaa58423e582 438 SUPERFAMILY SSF52540 108 189 1.81E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15140 ef70002b16be6d1f6d7beaa58423e582 438 SUPERFAMILY SSF52540 222 350 1.81E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 Gene3D G3DSA:3.30.300.20 204 281 7.0E-32 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 SMART SM00316 138 205 5.1E-6 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 SUPERFAMILY SSF54814 205 283 4.19E-29 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 370 419 7.5E-14 T 29-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 444 493 8.9E-18 T 29-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 SUPERFAMILY SSF69705 1 131 2.88E-39 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 SUPERFAMILY SSF54814 284 348 1.63E-15 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 Gene3D G3DSA:2.40.50.140 140 203 4.1E-12 T 29-03-2018 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 415 29.232 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 SUPERFAMILY SSF50249 137 204 1.97E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 347 4.3E-122 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 Pfam PF14520 Helix-hairpin-helix domain 436 491 2.4E-11 T 29-03-2018 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 SUPERFAMILY SSF47794 360 421 1.41E-14 T 29-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 Pfam PF13184 NusA-like KH domain 235 302 9.8E-28 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 Gene3D G3DSA:3.30.1480.10 1 134 8.7E-47 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 Gene3D G3DSA:3.30.300.20 283 353 1.3E-14 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 Pfam PF08529 NusA N-terminal domain 4 128 1.9E-37 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 Gene3D G3DSA:1.10.150.20 432 500 3.3E-16 T 29-03-2018 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 Gene3D G3DSA:1.10.150.20 357 426 4.4E-13 T 29-03-2018 THSYN_RS09445 773a1a7be015899a2cdd7e6d25a1a9c1 502 SUPERFAMILY SSF47794 433 495 4.55E-17 T 29-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 THSYN_RS21390 6b093bead712f9346a128daa07d4cc9a 835 Gene3D G3DSA:3.40.50.2000 499 813 3.2E-135 T 29-03-2018 THSYN_RS21390 6b093bead712f9346a128daa07d4cc9a 835 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 27 828 0.0 T 29-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THSYN_RS21390 6b093bead712f9346a128daa07d4cc9a 835 PIRSF PIRSF000460 12 835 4.7E-234 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THSYN_RS21390 6b093bead712f9346a128daa07d4cc9a 835 Pfam PF00343 Carbohydrate phosphorylase 117 828 0.0 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THSYN_RS21390 6b093bead712f9346a128daa07d4cc9a 835 SUPERFAMILY SSF53756 22 833 0.0 T 29-03-2018 THSYN_RS21390 6b093bead712f9346a128daa07d4cc9a 835 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 673 685 - T 29-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THSYN_RS21390 6b093bead712f9346a128daa07d4cc9a 835 Gene3D G3DSA:3.40.50.2000 17 498 5.6E-193 T 29-03-2018 THSYN_RS17825 29fed80fb128d6468c169b00abd838a6 284 Gene3D G3DSA:3.40.50.620 1 176 4.7E-75 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS17825 29fed80fb128d6468c169b00abd838a6 284 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 68 3.8E-8 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THSYN_RS17825 29fed80fb128d6468c169b00abd838a6 284 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 279 6.3E-94 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 THSYN_RS17825 29fed80fb128d6468c169b00abd838a6 284 Gene3D G3DSA:3.30.1300.10 177 282 4.4E-30 T 29-03-2018 THSYN_RS17825 29fed80fb128d6468c169b00abd838a6 284 Pfam PF02569 Pantoate-beta-alanine ligase 3 277 1.0E-99 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 THSYN_RS17825 29fed80fb128d6468c169b00abd838a6 284 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 40.624 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 THSYN_RS17825 29fed80fb128d6468c169b00abd838a6 284 SUPERFAMILY SSF52374 1 279 2.44E-104 T 29-03-2018 THSYN_RS06335 b8e674e8e6aea6511584c9a6b7fd2b6c 397 PRINTS PR00758 Arsenical pump membrane protein signature 55 79 6.2E-6 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THSYN_RS06335 b8e674e8e6aea6511584c9a6b7fd2b6c 397 PRINTS PR00758 Arsenical pump membrane protein signature 230 254 6.2E-6 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THSYN_RS06335 b8e674e8e6aea6511584c9a6b7fd2b6c 397 PRINTS PR00758 Arsenical pump membrane protein signature 167 192 6.2E-6 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THSYN_RS06335 b8e674e8e6aea6511584c9a6b7fd2b6c 397 PRINTS PR00758 Arsenical pump membrane protein signature 275 297 6.2E-6 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THSYN_RS06335 b8e674e8e6aea6511584c9a6b7fd2b6c 397 Pfam PF03600 Citrate transporter 11 313 7.7E-26 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 THSYN_RS12985 3d80f04a795978c6e186b216cfc6b0bd 173 Pfam PF04982 HPP family 48 169 7.1E-45 T 29-03-2018 IPR007065 HPP THSYN_RS20720 18b3c2261c0f3090ebbfa09f17e2cb03 213 Gene3D G3DSA:3.40.50.2020 1 193 5.8E-47 T 29-03-2018 THSYN_RS20720 18b3c2261c0f3090ebbfa09f17e2cb03 213 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 213 32.922 T 29-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THSYN_RS20720 18b3c2261c0f3090ebbfa09f17e2cb03 213 SUPERFAMILY SSF53271 1 209 2.63E-48 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like THSYN_RS20720 18b3c2261c0f3090ebbfa09f17e2cb03 213 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 12 187 1.4E-58 T 29-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THSYN_RS20720 18b3c2261c0f3090ebbfa09f17e2cb03 213 Pfam PF00156 Phosphoribosyl transferase domain 47 166 1.6E-13 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 ProSitePatterns PS00447 DNA polymerase family A signature. 727 746 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 TIGRFAM TIGR00593 pola: DNA polymerase I 7 901 2.3E-277 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 Gene3D G3DSA:1.10.150.20 183 258 1.1E-21 T 29-03-2018 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 SUPERFAMILY SSF88723 5 168 1.35E-54 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 7 168 9.4E-52 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 Pfam PF01612 3'-5' exonuclease 304 489 5.1E-40 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 Gene3D G3DSA:1.20.1060.10 515 629 2.2E-31 T 29-03-2018 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 Pfam PF00476 DNA polymerase family A 525 898 6.0E-152 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 651 666 1.3E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 673 696 1.3E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 848 861 1.3E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 628 650 1.3E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 727 752 1.3E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 764 775 1.3E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 786 797 1.3E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 818 834 1.3E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 703 716 1.3E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 SUPERFAMILY SSF47807 169 282 1.44E-28 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 Gene3D G3DSA:3.40.50.1010 5 182 6.3E-63 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 SUPERFAMILY SSF53098 301 489 3.51E-58 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 SMART SM00475 4 259 1.2E-116 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 SMART SM00482 659 865 6.7E-113 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 Gene3D G3DSA:3.30.420.10 312 514 1.1E-52 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 Gene3D G3DSA:3.30.70.370 727 901 6.4E-47 T 29-03-2018 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 Gene3D G3DSA:3.30.70.370 630 717 2.5E-19 T 29-03-2018 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 SUPERFAMILY SSF56672 496 901 8.56E-154 T 29-03-2018 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 169 257 2.1E-24 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 SMART SM00474 302 489 1.9E-42 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 THSYN_RS04830 6204ddb6a2b9bd445c4b7b45c3fe3ac8 901 SMART SM00279 171 206 1.2E-10 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 Gene3D G3DSA:4.10.480.10 235 309 2.1E-35 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 227 308 1.2E-32 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 Gene3D G3DSA:3.40.50.700 45 234 9.4E-48 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 62 206 1.2E-28 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 4 352 3.0E-168 T 29-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 PIRSF PIRSF000310 5 356 2.4E-141 T 29-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 116 139 4.2E-122 T 29-03-2018 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 232 250 4.2E-122 T 29-03-2018 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 256 282 4.2E-122 T 29-03-2018 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 188 211 4.2E-122 T 29-03-2018 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 70 94 4.2E-122 T 29-03-2018 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 214 231 4.2E-122 T 29-03-2018 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 284 297 4.2E-122 T 29-03-2018 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 159 183 4.2E-122 T 29-03-2018 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 47 69 4.2E-122 T 29-03-2018 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 SUPERFAMILY SSF56770 47 310 8.77E-89 T 29-03-2018 THSYN_RS28445 8f9bb735839b7332ac721a153608b006 378 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 16 45 2.1E-6 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 391 495 3.3E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 475 6.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 440 6.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 454 6.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 494 6.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 Gene3D G3DSA:3.30.565.10 347 496 1.2E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 SUPERFAMILY SSF55874 337 495 4.71E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 SMART SM00388 280 346 7.3E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 Gene3D G3DSA:1.10.287.130 274 342 2.9E-11 T 29-03-2018 THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 SUPERFAMILY SSF47384 275 344 3.14E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 SUPERFAMILY SSF55785 136 263 2.65E-23 T 29-03-2018 IPR000014 PAS domain THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 SMART SM00387 389 496 3.1E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 SMART SM00091 151 217 2.2E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 SMART SM00091 23 91 0.004 T 29-03-2018 IPR000014 PAS domain THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 Pfam PF00512 His Kinase A (phospho-acceptor) domain 281 344 2.1E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 Gene3D G3DSA:3.30.450.20 21 132 4.3E-16 T 29-03-2018 THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 Gene3D G3DSA:3.30.450.20 133 273 1.5E-31 T 29-03-2018 THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 149 272 1.3E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 SUPERFAMILY SSF55785 21 137 3.91E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 Pfam PF08448 PAS fold 29 141 1.4E-11 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS11935 7abaa277e4785d70efeec108f331cf45 496 Pfam PF08448 PAS fold 157 267 6.7E-14 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS21310 577ae339d413174e6ee8b9faf9c565a4 403 TIGRFAM TIGR04063 stp3: PEP-CTERM/exosortase A-associated glycosyltransferase, Daro_2409 family 2 399 3.0E-185 T 29-03-2018 IPR024004 Glycosyltransferase family 1, Daro2409 family THSYN_RS21310 577ae339d413174e6ee8b9faf9c565a4 403 Pfam PF00534 Glycosyl transferases group 1 215 374 9.5E-29 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS21310 577ae339d413174e6ee8b9faf9c565a4 403 Gene3D G3DSA:3.40.50.2000 4 205 5.9E-25 T 29-03-2018 THSYN_RS21310 577ae339d413174e6ee8b9faf9c565a4 403 SUPERFAMILY SSF53756 2 396 7.46E-74 T 29-03-2018 THSYN_RS21310 577ae339d413174e6ee8b9faf9c565a4 403 Gene3D G3DSA:3.40.50.2000 206 380 7.2E-41 T 29-03-2018 THSYN_RS21310 577ae339d413174e6ee8b9faf9c565a4 403 Pfam PF13579 Glycosyl transferase 4-like domain 15 191 3.3E-26 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS19775 eda925c2769876777c8c87ced5fd1ea9 158 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 156 5.3E-58 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THSYN_RS19775 eda925c2769876777c8c87ced5fd1ea9 158 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 35.581 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THSYN_RS19775 eda925c2769876777c8c87ced5fd1ea9 158 SUPERFAMILY SSF52374 3 155 8.04E-43 T 29-03-2018 THSYN_RS19775 eda925c2769876777c8c87ced5fd1ea9 158 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 59 7.6E-15 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THSYN_RS19775 eda925c2769876777c8c87ced5fd1ea9 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 1.5E-49 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THSYN_RS19775 eda925c2769876777c8c87ced5fd1ea9 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.5E-49 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THSYN_RS19775 eda925c2769876777c8c87ced5fd1ea9 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.5E-49 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THSYN_RS19775 eda925c2769876777c8c87ced5fd1ea9 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.5E-49 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THSYN_RS19775 eda925c2769876777c8c87ced5fd1ea9 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.5E-49 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THSYN_RS19775 eda925c2769876777c8c87ced5fd1ea9 158 Pfam PF01467 Cytidylyltransferase-like 5 133 1.1E-19 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THSYN_RS19775 eda925c2769876777c8c87ced5fd1ea9 158 Gene3D G3DSA:3.40.50.620 1 158 6.0E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 Gene3D G3DSA:2.40.30.10 275 384 6.2E-16 T 29-03-2018 THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 Pfam PF03764 Elongation factor G, domain IV 463 581 7.1E-39 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 SUPERFAMILY SSF54980 389 466 3.96E-18 T 29-03-2018 IPR035647 EF-G domain III/V-like THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 SUPERFAMILY SSF54980 584 675 3.09E-20 T 29-03-2018 IPR035647 EF-G domain III/V-like THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 Gene3D G3DSA:3.30.70.870 385 476 2.4E-26 T 29-03-2018 THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 SUPERFAMILY SSF54211 463 583 2.78E-40 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 Gene3D G3DSA:3.30.230.10 477 597 9.5E-41 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 PRINTS PR00315 GTP-binding elongation factor signature 129 138 2.2E-5 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 PRINTS PR00315 GTP-binding elongation factor signature 11 24 2.2E-5 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 PRINTS PR00315 GTP-binding elongation factor signature 77 87 2.2E-5 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 Pfam PF00679 Elongation factor G C-terminus 584 671 8.2E-23 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 SUPERFAMILY SSF52540 4 262 9.57E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 Gene3D G3DSA:3.30.70.240 598 676 2.2E-20 T 29-03-2018 THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 Gene3D G3DSA:3.40.50.300 2 267 1.3E-28 T 29-03-2018 THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 SMART SM00889 464 582 5.0E-59 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 Pfam PF14492 Elongation Factor G, domain II 389 461 1.4E-22 T 29-03-2018 THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 Pfam PF00009 Elongation factor Tu GTP binding domain 8 261 7.7E-35 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 SMART SM00838 584 672 1.1E-28 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like THSYN_RS22590 1ae22ca626405b94cab3fe4ce6a7cb6d 681 SUPERFAMILY SSF50447 246 379 5.89E-22 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS11055 983a8f365f252b8936aa7a0ee0e635ee 322 Pfam PF00849 RNA pseudouridylate synthase 107 237 2.1E-14 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS11055 983a8f365f252b8936aa7a0ee0e635ee 322 SMART SM00363 43 104 1.1E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS11055 983a8f365f252b8936aa7a0ee0e635ee 322 Gene3D G3DSA:3.30.70.1560 189 257 1.5E-20 T 29-03-2018 THSYN_RS11055 983a8f365f252b8936aa7a0ee0e635ee 322 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 145 159 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 THSYN_RS11055 983a8f365f252b8936aa7a0ee0e635ee 322 Gene3D G3DSA:3.10.290.10 40 102 1.9E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS11055 983a8f365f252b8936aa7a0ee0e635ee 322 SUPERFAMILY SSF55120 105 277 1.25E-44 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS11055 983a8f365f252b8936aa7a0ee0e635ee 322 Pfam PF01479 S4 domain 43 88 1.3E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS11055 983a8f365f252b8936aa7a0ee0e635ee 322 SUPERFAMILY SSF55174 44 135 3.79E-18 T 29-03-2018 THSYN_RS11055 983a8f365f252b8936aa7a0ee0e635ee 322 Gene3D G3DSA:3.30.70.580 103 188 2.4E-17 T 29-03-2018 THSYN_RS11055 983a8f365f252b8936aa7a0ee0e635ee 322 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 111 272 4.5E-52 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 THSYN_RS04500 1240414039f389dd20f8ec36c76b2189 788 Pfam PF08463 EcoEI R protein C-terminal 630 784 1.2E-25 T 29-03-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 THSYN_RS04500 1240414039f389dd20f8ec36c76b2189 788 Gene3D G3DSA:3.40.50.300 149 337 5.5E-25 T 29-03-2018 THSYN_RS04500 1240414039f389dd20f8ec36c76b2189 788 Gene3D G3DSA:3.40.50.300 398 670 3.0E-11 T 29-03-2018 THSYN_RS04500 1240414039f389dd20f8ec36c76b2189 788 Pfam PF04851 Type III restriction enzyme, res subunit 168 325 1.7E-41 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS04500 1240414039f389dd20f8ec36c76b2189 788 SUPERFAMILY SSF52540 182 327 8.49E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04500 1240414039f389dd20f8ec36c76b2189 788 SUPERFAMILY SSF52540 387 528 8.49E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04500 1240414039f389dd20f8ec36c76b2189 788 SMART SM00487 165 360 1.6E-17 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS04500 1240414039f389dd20f8ec36c76b2189 788 Pfam PF00271 Helicase conserved C-terminal domain 410 526 9.4E-8 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS25385 61acecf6ca9ef573e42fa27b52c43458 131 SUPERFAMILY SSF81593 11 102 1.8E-12 T 29-03-2018 THSYN_RS25385 61acecf6ca9ef573e42fa27b52c43458 131 SMART SM00748 12 118 6.2E-4 T 29-03-2018 IPR007842 HEPN domain THSYN_RS25385 61acecf6ca9ef573e42fa27b52c43458 131 Gene3D G3DSA:1.20.120.330 1 126 1.7E-18 T 29-03-2018 THSYN_RS25385 61acecf6ca9ef573e42fa27b52c43458 131 Pfam PF05168 HEPN domain 9 117 4.4E-15 T 29-03-2018 IPR007842 HEPN domain THSYN_RS23830 c976f48e796279d544a757c6e2f86b54 168 ProSitePatterns PS00585 Ribosomal protein S5 signature. 30 62 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site THSYN_RS23830 c976f48e796279d544a757c6e2f86b54 168 SUPERFAMILY SSF54768 10 78 2.09E-22 T 29-03-2018 THSYN_RS23830 c976f48e796279d544a757c6e2f86b54 168 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 13 164 1.7E-62 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 THSYN_RS23830 c976f48e796279d544a757c6e2f86b54 168 Gene3D G3DSA:3.30.230.10 78 168 4.4E-29 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS23830 c976f48e796279d544a757c6e2f86b54 168 Pfam PF00333 Ribosomal protein S5, N-terminal domain 14 76 1.3E-26 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 THSYN_RS23830 c976f48e796279d544a757c6e2f86b54 168 Pfam PF03719 Ribosomal protein S5, C-terminal domain 88 159 7.7E-29 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 THSYN_RS23830 c976f48e796279d544a757c6e2f86b54 168 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 165 33.895 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 THSYN_RS23830 c976f48e796279d544a757c6e2f86b54 168 SUPERFAMILY SSF54211 82 161 1.16E-24 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS23830 c976f48e796279d544a757c6e2f86b54 168 Gene3D G3DSA:3.30.160.20 12 74 8.9E-25 T 29-03-2018 THSYN_RS12690 adada8cb3268bf706cc16b8cf1c49d9d 286 Gene3D G3DSA:3.90.260.10 166 250 0.0061 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS12690 adada8cb3268bf706cc16b8cf1c49d9d 286 Pfam PF01841 Transglutaminase-like superfamily 128 234 1.1E-22 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS12690 adada8cb3268bf706cc16b8cf1c49d9d 286 SMART SM00460 171 236 4.8E-20 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS12690 adada8cb3268bf706cc16b8cf1c49d9d 286 SUPERFAMILY SSF54001 7 269 1.82E-43 T 29-03-2018 THSYN_RS12690 adada8cb3268bf706cc16b8cf1c49d9d 286 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 4 82 4.1E-18 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal THSYN_RS28975 e813ba6aa45baf89eaf654cdcc1d8157 360 Gene3D G3DSA:3.40.50.720 1 205 6.0E-24 T 29-03-2018 THSYN_RS28975 e813ba6aa45baf89eaf654cdcc1d8157 360 Gene3D G3DSA:3.90.25.10 206 247 1.0E-23 T 29-03-2018 THSYN_RS28975 e813ba6aa45baf89eaf654cdcc1d8157 360 Gene3D G3DSA:3.90.25.10 248 360 1.9E-33 T 29-03-2018 THSYN_RS28975 e813ba6aa45baf89eaf654cdcc1d8157 360 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 2 344 56.093 T 29-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 THSYN_RS28975 e813ba6aa45baf89eaf654cdcc1d8157 360 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 334 4.3E-155 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS28975 e813ba6aa45baf89eaf654cdcc1d8157 360 SUPERFAMILY SSF51735 2 340 3.75E-83 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS28975 e813ba6aa45baf89eaf654cdcc1d8157 360 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 2 341 2.6E-174 T 29-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 THSYN_RS29655 86ab0f07d77a0e1685fd85567ce0b933 118 Pfam PF05717 IS66 Orf2 like protein 9 105 5.4E-30 T 29-03-2018 IPR008878 Transposase IS66, Orf2 THSYN_RS18295 86ab0f07d77a0e1685fd85567ce0b933 118 Pfam PF05717 IS66 Orf2 like protein 9 105 5.4E-30 T 29-03-2018 IPR008878 Transposase IS66, Orf2 THSYN_RS09695 86ab0f07d77a0e1685fd85567ce0b933 118 Pfam PF05717 IS66 Orf2 like protein 9 105 5.4E-30 T 29-03-2018 IPR008878 Transposase IS66, Orf2 THSYN_RS18635 86ab0f07d77a0e1685fd85567ce0b933 118 Pfam PF05717 IS66 Orf2 like protein 9 105 5.4E-30 T 29-03-2018 IPR008878 Transposase IS66, Orf2 THSYN_RS09365 86ab0f07d77a0e1685fd85567ce0b933 118 Pfam PF05717 IS66 Orf2 like protein 9 105 5.4E-30 T 29-03-2018 IPR008878 Transposase IS66, Orf2 THSYN_RS30525 86ab0f07d77a0e1685fd85567ce0b933 118 Pfam PF05717 IS66 Orf2 like protein 9 105 5.4E-30 T 29-03-2018 IPR008878 Transposase IS66, Orf2 THSYN_RS09650 7a4412ed09c2c42b834e9feeada01022 198 SUPERFAMILY SSF141523 60 196 4.45E-24 T 29-03-2018 THSYN_RS09650 7a4412ed09c2c42b834e9feeada01022 198 Pfam PF03734 L,D-transpeptidase catalytic domain 60 196 1.6E-17 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 THSYN_RS09650 7a4412ed09c2c42b834e9feeada01022 198 Gene3D G3DSA:2.40.440.10 58 197 3.7E-23 T 29-03-2018 THSYN_RS19135 0526da25b48dfedf4c7a61c1407b23d9 365 ProDom PD074023 BIOSYNTHESIS COBALAMIN CBIM COBALT PRECURSOR SIGNAL NICKEL MEMBRANE ABC PROTEIN 260 336 6.0E-6 T 29-03-2018 IPR020486 Uncharacterised protein family MJ1570 THSYN_RS19135 0526da25b48dfedf4c7a61c1407b23d9 365 Pfam PF13190 PDGLE domain 254 348 2.0E-9 T 29-03-2018 IPR025937 PDGLE domain THSYN_RS19135 0526da25b48dfedf4c7a61c1407b23d9 365 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 220 1.4E-62 T 29-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 THSYN_RS28145 83307556b0249630148349f8d64a1511 581 SUPERFAMILY SSF52467 167 362 2.25E-46 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS28145 83307556b0249630148349f8d64a1511 581 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 427 446 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 THSYN_RS28145 83307556b0249630148349f8d64a1511 581 SUPERFAMILY SSF52518 10 190 8.06E-50 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS28145 83307556b0249630148349f8d64a1511 581 SUPERFAMILY SSF52518 366 579 3.99E-59 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS28145 83307556b0249630148349f8d64a1511 581 Gene3D G3DSA:3.40.50.1220 207 351 1.2E-40 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS28145 83307556b0249630148349f8d64a1511 581 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 203 333 4.8E-34 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 THSYN_RS28145 83307556b0249630148349f8d64a1511 581 Gene3D G3DSA:3.40.50.970 5 206 2.0E-50 T 29-03-2018 THSYN_RS28145 83307556b0249630148349f8d64a1511 581 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 11 580 2.8E-176 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 THSYN_RS28145 83307556b0249630148349f8d64a1511 581 Gene3D G3DSA:3.40.50.970 352 577 3.0E-45 T 29-03-2018 THSYN_RS28145 83307556b0249630148349f8d64a1511 581 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 11 182 4.1E-45 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THSYN_RS28145 83307556b0249630148349f8d64a1511 581 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 390 557 1.3E-40 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THSYN_RS26575 3601b9ce38bc41555f1adf0468902774 404 Gene3D G3DSA:3.90.1150.10 232 404 1.2E-48 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS26575 3601b9ce38bc41555f1adf0468902774 404 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 395 52.135 T 29-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 THSYN_RS26575 3601b9ce38bc41555f1adf0468902774 404 Pfam PF00266 Aminotransferase class-V 5 367 6.5E-80 T 29-03-2018 IPR000192 Aminotransferase class V domain THSYN_RS26575 3601b9ce38bc41555f1adf0468902774 404 Gene3D G3DSA:3.40.640.10 1 231 3.2E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS26575 3601b9ce38bc41555f1adf0468902774 404 PIRSF PIRSF005572 2 384 1.7E-124 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 THSYN_RS26575 3601b9ce38bc41555f1adf0468902774 404 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 1 404 1.8E-213 T 29-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 THSYN_RS26575 3601b9ce38bc41555f1adf0468902774 404 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 197 216 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site THSYN_RS26575 3601b9ce38bc41555f1adf0468902774 404 SUPERFAMILY SSF53383 5 389 2.72E-110 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS07845 c686e9b06bf18ce0c7105545aa519acf 212 Gene3D G3DSA:3.40.50.300 148 196 5.8E-6 T 29-03-2018 THSYN_RS07845 c686e9b06bf18ce0c7105545aa519acf 212 Gene3D G3DSA:2.30.30.110 1 109 7.1E-9 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS07845 c686e9b06bf18ce0c7105545aa519acf 212 SUPERFAMILY SSF50118 1 109 5.23E-12 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS07845 c686e9b06bf18ce0c7105545aa519acf 212 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 103 4.6E-5 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS07845 c686e9b06bf18ce0c7105545aa519acf 212 Gene3D G3DSA:3.40.50.300 110 147 1.3E-5 T 29-03-2018 THSYN_RS32440 a4c56526b8370928501d2230f0bbd2ce 373 Gene3D G3DSA:1.10.3290.10 22 295 2.0E-40 T 29-03-2018 IPR003812 Fido domain THSYN_RS32440 a4c56526b8370928501d2230f0bbd2ce 373 SUPERFAMILY SSF140931 99 290 1.12E-27 T 29-03-2018 IPR003812 Fido domain THSYN_RS32440 a4c56526b8370928501d2230f0bbd2ce 373 Gene3D G3DSA:1.10.10.10 300 368 4.2E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS32440 a4c56526b8370928501d2230f0bbd2ce 373 Pfam PF13776 Domain of unknown function (DUF4172) 2 83 1.2E-26 T 29-03-2018 IPR025230 Domain of unknown function DUF4172 THSYN_RS32440 a4c56526b8370928501d2230f0bbd2ce 373 Pfam PF02661 Fic/DOC family 113 224 1.3E-16 T 29-03-2018 IPR003812 Fido domain THSYN_RS02155 1f737d505c274b9c288188887844c3ae 222 Pfam PF00072 Response regulator receiver domain 3 112 7.7E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS02155 1f737d505c274b9c288188887844c3ae 222 SMART SM00862 145 216 1.8E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS02155 1f737d505c274b9c288188887844c3ae 222 SMART SM00448 1 112 2.1E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS02155 1f737d505c274b9c288188887844c3ae 222 Gene3D G3DSA:3.40.50.2300 1 115 2.3E-35 T 29-03-2018 THSYN_RS02155 1f737d505c274b9c288188887844c3ae 222 SUPERFAMILY SSF52172 1 173 1.01E-39 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS02155 1f737d505c274b9c288188887844c3ae 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 215 1.2E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS02155 1f737d505c274b9c288188887844c3ae 222 Gene3D G3DSA:1.10.10.10 116 222 5.1E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS04535 41bee6c008df2cb0a9b395dc8fe36299 119 Gene3D G3DSA:1.10.260.40 48 119 0.0021 T 29-03-2018 THSYN_RS02110 d3b071d93eb99923732614f36bb0b7e7 156 Pfam PF02470 MlaD protein 39 118 4.4E-23 T 29-03-2018 IPR003399 Mce/MlaD THSYN_RS02110 d3b071d93eb99923732614f36bb0b7e7 156 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 4 148 6.2E-57 T 29-03-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 479 489 3.6E-24 T 29-03-2018 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 321 335 3.6E-24 T 29-03-2018 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 164 178 3.6E-24 T 29-03-2018 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 567 3.6E-24 T 29-03-2018 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 532 551 3.6E-24 T 29-03-2018 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 3 692 0.0 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 8 696 40.702 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 SUPERFAMILY SSF81660 332 466 1.18E-34 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 Gene3D G3DSA:3.40.50.1000 459 591 7.1E-33 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 Pfam PF00122 E1-E2 ATPase 127 300 2.2E-33 T 29-03-2018 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 389 620 3.4E-47 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 105 357 6.4E-31 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 Pfam PF00702 haloacid dehalogenase-like hydrolase 317 546 1.8E-32 T 29-03-2018 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 SUPERFAMILY SSF56784 309 333 1.38E-38 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 SUPERFAMILY SSF56784 391 420 1.38E-38 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 SUPERFAMILY SSF56784 451 575 1.38E-38 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 SUPERFAMILY SSF81653 127 217 5.1E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 323 329 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 SUPERFAMILY SSF81665 30 107 5.1E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 SUPERFAMILY SSF81665 218 315 5.1E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 Gene3D G3DSA:3.40.1110.10 332 458 9.6E-24 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THSYN_RS08475 8c9ad703531a4a839e5cfadfd356cf7c 698 Gene3D G3DSA:2.70.150.10 28 218 7.4E-26 T 29-03-2018 THSYN_RS06015 76e6ed77e8dae24ba8d9a194eb0d6183 330 SMART SM00987 172 320 5.1E-39 T 29-03-2018 THSYN_RS06015 76e6ed77e8dae24ba8d9a194eb0d6183 330 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 158 323 8.8E-64 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 THSYN_RS06015 76e6ed77e8dae24ba8d9a194eb0d6183 330 SUPERFAMILY SSF52141 147 326 8.83E-63 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THSYN_RS06015 76e6ed77e8dae24ba8d9a194eb0d6183 330 Pfam PF03167 Uracil DNA glycosylase superfamily 172 319 2.5E-43 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THSYN_RS06015 76e6ed77e8dae24ba8d9a194eb0d6183 330 Gene3D G3DSA:3.40.470.10 142 328 1.6E-60 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THSYN_RS06015 76e6ed77e8dae24ba8d9a194eb0d6183 330 SMART SM00986 172 320 5.1E-39 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THSYN_RS19025 cdc311dc339dc936e2247d5b6a2db811 131 Pfam PF02635 DsrE/DsrF-like family 25 131 3.1E-15 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein THSYN_RS19025 cdc311dc339dc936e2247d5b6a2db811 131 SUPERFAMILY SSF75169 23 131 1.26E-20 T 29-03-2018 IPR027396 DsrEFH-like THSYN_RS19025 cdc311dc339dc936e2247d5b6a2db811 131 Gene3D G3DSA:3.40.1260.10 18 131 1.2E-23 T 29-03-2018 THSYN_RS24325 549508293ef01a30d829694b4c267a9b 261 Gene3D G3DSA:3.40.50.720 1 245 1.1E-77 T 29-03-2018 THSYN_RS24325 549508293ef01a30d829694b4c267a9b 261 Pfam PF00899 ThiF family 9 241 2.6E-63 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THSYN_RS24325 549508293ef01a30d829694b4c267a9b 261 SUPERFAMILY SSF69572 3 246 5.49E-89 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THSYN_RS18815 683983f8d84cc7f0ea799ced4a995766 137 SUPERFAMILY SSF47598 12 55 1.22E-7 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS18815 683983f8d84cc7f0ea799ced4a995766 137 Gene3D G3DSA:1.10.1220.10 14 56 4.9E-10 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS18785 6daadabd7e4ee615e48ecaec43c5cd91 270 SUPERFAMILY SSF140931 61 227 1.12E-28 T 29-03-2018 IPR003812 Fido domain THSYN_RS18785 6daadabd7e4ee615e48ecaec43c5cd91 270 Pfam PF02661 Fic/DOC family 85 193 7.3E-16 T 29-03-2018 IPR003812 Fido domain THSYN_RS18785 6daadabd7e4ee615e48ecaec43c5cd91 270 Gene3D G3DSA:1.10.3290.10 2 270 9.3E-49 T 29-03-2018 IPR003812 Fido domain THSYN_RS16550 2ddfb65a9e033ad8ca1f315258424021 426 Gene3D G3DSA:3.50.50.60 9 215 2.9E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS16550 2ddfb65a9e033ad8ca1f315258424021 426 Pfam PF12831 FAD dependent oxidoreductase 11 47 8.9E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS16550 2ddfb65a9e033ad8ca1f315258424021 426 SUPERFAMILY SSF51905 5 415 3.24E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS16550 2ddfb65a9e033ad8ca1f315258424021 426 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.5E-6 T 29-03-2018 THSYN_RS16550 2ddfb65a9e033ad8ca1f315258424021 426 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 350 366 3.5E-6 T 29-03-2018 THSYN_RS16550 2ddfb65a9e033ad8ca1f315258424021 426 Gene3D G3DSA:3.50.50.60 221 426 3.5E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS05110 acdbad5856129910c02a12500e66e2e8 193 Pfam PF05685 Putative restriction endonuclease 21 175 8.4E-32 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS05110 acdbad5856129910c02a12500e66e2e8 193 Gene3D G3DSA:3.90.1570.10 1 189 7.9E-44 T 29-03-2018 THSYN_RS05110 acdbad5856129910c02a12500e66e2e8 193 SUPERFAMILY SSF52980 2 184 4.77E-22 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS02630 0e56a89e728b95cb27c57cfd8f70df0b 473 PIRSF PIRSF001549 9 463 1.8E-111 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 THSYN_RS02630 0e56a89e728b95cb27c57cfd8f70df0b 473 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 10 465 25.797 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 THSYN_RS02630 0e56a89e728b95cb27c57cfd8f70df0b 473 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 15 441 9.5E-109 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 THSYN_RS02630 0e56a89e728b95cb27c57cfd8f70df0b 473 Pfam PF13393 Histidyl-tRNA synthetase 17 349 9.7E-35 T 29-03-2018 THSYN_RS02630 0e56a89e728b95cb27c57cfd8f70df0b 473 SUPERFAMILY SSF55681 14 357 8.3E-68 T 29-03-2018 THSYN_RS02630 0e56a89e728b95cb27c57cfd8f70df0b 473 Gene3D G3DSA:3.30.930.10 8 362 4.3E-83 T 29-03-2018 THSYN_RS02630 0e56a89e728b95cb27c57cfd8f70df0b 473 SUPERFAMILY SSF52954 365 462 3.78E-17 T 29-03-2018 IPR004154 Anticodon-binding THSYN_RS02630 0e56a89e728b95cb27c57cfd8f70df0b 473 Pfam PF03129 Anticodon binding domain 368 461 1.4E-12 T 29-03-2018 IPR004154 Anticodon-binding THSYN_RS02630 0e56a89e728b95cb27c57cfd8f70df0b 473 Gene3D G3DSA:3.40.50.800 363 464 4.0E-20 T 29-03-2018 IPR004154 Anticodon-binding THSYN_RS21630 b344bffd81b729699ba3074f98cfd1ed 514 PIRSF PIRSF017184 14 506 5.2E-131 T 29-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 THSYN_RS21630 b344bffd81b729699ba3074f98cfd1ed 514 Gene3D G3DSA:3.40.1190.20 233 510 3.2E-49 T 29-03-2018 IPR029056 Ribokinase-like THSYN_RS21630 b344bffd81b729699ba3074f98cfd1ed 514 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 438 448 - T 29-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site THSYN_RS21630 b344bffd81b729699ba3074f98cfd1ed 514 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 237 502 6.7E-63 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 THSYN_RS21630 b344bffd81b729699ba3074f98cfd1ed 514 Pfam PF03853 YjeF-related protein N-terminus 38 196 5.8E-42 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THSYN_RS21630 b344bffd81b729699ba3074f98cfd1ed 514 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 232 506 22.221 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 THSYN_RS21630 b344bffd81b729699ba3074f98cfd1ed 514 Gene3D G3DSA:3.40.50.10260 5 232 5.5E-66 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THSYN_RS21630 b344bffd81b729699ba3074f98cfd1ed 514 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 17 217 25.418 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THSYN_RS21630 b344bffd81b729699ba3074f98cfd1ed 514 Pfam PF01256 Carbohydrate kinase 255 492 4.4E-57 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 THSYN_RS21630 b344bffd81b729699ba3074f98cfd1ed 514 SUPERFAMILY SSF64153 15 254 1.03E-62 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THSYN_RS21630 b344bffd81b729699ba3074f98cfd1ed 514 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 18 217 9.4E-46 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THSYN_RS21630 b344bffd81b729699ba3074f98cfd1ed 514 SUPERFAMILY SSF53613 237 502 1.31E-69 T 29-03-2018 IPR029056 Ribokinase-like THSYN_RS20635 4189b20a1e567652ea54e8022a55631c 281 Pfam PF08867 FRG domain 23 107 2.3E-17 T 29-03-2018 IPR014966 FRG domain THSYN_RS20635 4189b20a1e567652ea54e8022a55631c 281 SMART SM00901 20 114 1.5E-30 T 29-03-2018 IPR014966 FRG domain THSYN_RS21095 7c060704a92702e452f896a81bda132f 319 Pfam PF04754 Putative transposase, YhgA-like 3 203 1.4E-28 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS21095 7c060704a92702e452f896a81bda132f 319 Pfam PF14261 Domain of unknown function (DUF4351) 261 313 3.6E-7 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS25465 5d4445f58d16b31c97aed0fe6b2e0f9e 288 Pfam PF02563 Polysaccharide biosynthesis/export protein 103 175 1.5E-19 T 29-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 THSYN_RS25465 5d4445f58d16b31c97aed0fe6b2e0f9e 288 Gene3D G3DSA:3.10.560.10 172 264 7.2E-20 T 29-03-2018 THSYN_RS25465 5d4445f58d16b31c97aed0fe6b2e0f9e 288 Gene3D G3DSA:3.30.1950.10 110 171 6.7E-14 T 29-03-2018 THSYN_RS25465 5d4445f58d16b31c97aed0fe6b2e0f9e 288 Pfam PF10531 SLBB domain 183 234 8.3E-9 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS16845 c2c3623b4c3f701e5f2d3c7696031dc7 243 Pfam PF04452 RNA methyltransferase 22 236 1.2E-59 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS16845 c2c3623b4c3f701e5f2d3c7696031dc7 243 SUPERFAMILY SSF88697 2 66 6.79E-12 T 29-03-2018 IPR015947 PUA-like domain THSYN_RS16845 c2c3623b4c3f701e5f2d3c7696031dc7 243 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 2 241 9.9E-48 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS16845 c2c3623b4c3f701e5f2d3c7696031dc7 243 SUPERFAMILY SSF75217 74 241 2.18E-47 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases THSYN_RS16845 c2c3623b4c3f701e5f2d3c7696031dc7 243 PIRSF PIRSF015601 3 241 7.8E-48 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS16845 c2c3623b4c3f701e5f2d3c7696031dc7 243 Gene3D G3DSA:3.40.1280.10 74 243 2.7E-52 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THSYN_RS16845 c2c3623b4c3f701e5f2d3c7696031dc7 243 Gene3D G3DSA:2.40.240.20 1 72 1.3E-16 T 29-03-2018 THSYN_RS02380 1884f869031800eee7931090ae0b7800 385 Pfam PF14319 Transposase zinc-binding domain 16 114 9.0E-32 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS02380 1884f869031800eee7931090ae0b7800 385 Pfam PF04986 Putative transposase 140 320 4.6E-56 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS31595 1884f869031800eee7931090ae0b7800 385 Pfam PF14319 Transposase zinc-binding domain 16 114 9.0E-32 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS31595 1884f869031800eee7931090ae0b7800 385 Pfam PF04986 Putative transposase 140 320 4.6E-56 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS01250 1884f869031800eee7931090ae0b7800 385 Pfam PF14319 Transposase zinc-binding domain 16 114 9.0E-32 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS01250 1884f869031800eee7931090ae0b7800 385 Pfam PF04986 Putative transposase 140 320 4.6E-56 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS11585 1884f869031800eee7931090ae0b7800 385 Pfam PF14319 Transposase zinc-binding domain 16 114 9.0E-32 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS11585 1884f869031800eee7931090ae0b7800 385 Pfam PF04986 Putative transposase 140 320 4.6E-56 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS00790 1884f869031800eee7931090ae0b7800 385 Pfam PF14319 Transposase zinc-binding domain 16 114 9.0E-32 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS00790 1884f869031800eee7931090ae0b7800 385 Pfam PF04986 Putative transposase 140 320 4.6E-56 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS32965 1884f869031800eee7931090ae0b7800 385 Pfam PF14319 Transposase zinc-binding domain 16 114 9.0E-32 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS32965 1884f869031800eee7931090ae0b7800 385 Pfam PF04986 Putative transposase 140 320 4.6E-56 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS06375 1884f869031800eee7931090ae0b7800 385 Pfam PF14319 Transposase zinc-binding domain 16 114 9.0E-32 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS06375 1884f869031800eee7931090ae0b7800 385 Pfam PF04986 Putative transposase 140 320 4.6E-56 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS24830 1884f869031800eee7931090ae0b7800 385 Pfam PF14319 Transposase zinc-binding domain 16 114 9.0E-32 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS24830 1884f869031800eee7931090ae0b7800 385 Pfam PF04986 Putative transposase 140 320 4.6E-56 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS27680 1884f869031800eee7931090ae0b7800 385 Pfam PF14319 Transposase zinc-binding domain 16 114 9.0E-32 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS27680 1884f869031800eee7931090ae0b7800 385 Pfam PF04986 Putative transposase 140 320 4.6E-56 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS11365 1884f869031800eee7931090ae0b7800 385 Pfam PF14319 Transposase zinc-binding domain 16 114 9.0E-32 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS11365 1884f869031800eee7931090ae0b7800 385 Pfam PF04986 Putative transposase 140 320 4.6E-56 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS32515 1884f869031800eee7931090ae0b7800 385 Pfam PF14319 Transposase zinc-binding domain 16 114 9.0E-32 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS32515 1884f869031800eee7931090ae0b7800 385 Pfam PF04986 Putative transposase 140 320 4.6E-56 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS17015 1884f869031800eee7931090ae0b7800 385 Pfam PF14319 Transposase zinc-binding domain 16 114 9.0E-32 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS17015 1884f869031800eee7931090ae0b7800 385 Pfam PF04986 Putative transposase 140 320 4.6E-56 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS00685 995db58fe2ee586bf26d3a1108ce2bfe 545 SUPERFAMILY SSF55469 73 256 1.31E-11 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THSYN_RS00685 995db58fe2ee586bf26d3a1108ce2bfe 545 SUPERFAMILY SSF55469 318 348 1.81E-14 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THSYN_RS00685 995db58fe2ee586bf26d3a1108ce2bfe 545 SUPERFAMILY SSF55469 421 535 1.81E-14 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THSYN_RS00685 995db58fe2ee586bf26d3a1108ce2bfe 545 Gene3D G3DSA:3.40.109.10 1 238 4.5E-32 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THSYN_RS00685 995db58fe2ee586bf26d3a1108ce2bfe 545 Gene3D G3DSA:3.40.109.10 299 540 1.9E-30 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THSYN_RS00685 995db58fe2ee586bf26d3a1108ce2bfe 545 Pfam PF00881 Nitroreductase family 72 219 2.4E-5 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 SUPERFAMILY SSF53335 67 248 4.63E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 SUPERFAMILY SSF48452 339 470 2.05E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 Pfam PF01739 CheR methyltransferase, SAM binding domain 66 248 2.5E-45 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 SMART SM00028 406 439 0.0042 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 SMART SM00028 440 473 120.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 PRINTS PR00996 Glutamate methyltransferase family signature 223 246 6.8E-17 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 PRINTS PR00996 Glutamate methyltransferase family signature 204 218 6.8E-17 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 PRINTS PR00996 Glutamate methyltransferase family signature 134 150 6.8E-17 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 PRINTS PR00996 Glutamate methyltransferase family signature 6 19 6.8E-17 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 Gene3D G3DSA:1.10.155.10 1 64 5.1E-8 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 Gene3D G3DSA:3.40.50.150 65 250 1.7E-37 T 29-03-2018 THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 SMART SM00138 9 264 4.1E-56 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 Gene3D G3DSA:1.25.40.10 325 418 9.8E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 Pfam PF13432 Tetratricopeptide repeat 412 468 1.6E-6 T 29-03-2018 THSYN_RS04370 e2ce6b51b9c1a654cdc3532c36397bc9 507 Gene3D G3DSA:1.25.40.10 419 470 3.3E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS09280 796fcc290d1badbdf67da4f4a2523e09 1044 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 490 502 2.4E-13 T 29-03-2018 THSYN_RS09280 796fcc290d1badbdf67da4f4a2523e09 1044 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 352 368 2.4E-13 T 29-03-2018 THSYN_RS09280 796fcc290d1badbdf67da4f4a2523e09 1044 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 380 394 2.4E-13 T 29-03-2018 THSYN_RS09280 796fcc290d1badbdf67da4f4a2523e09 1044 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 531 555 2.4E-13 T 29-03-2018 THSYN_RS09280 796fcc290d1badbdf67da4f4a2523e09 1044 Gene3D G3DSA:3.40.50.150 350 631 4.4E-32 T 29-03-2018 THSYN_RS09280 796fcc290d1badbdf67da4f4a2523e09 1044 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 493 499 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS09280 796fcc290d1badbdf67da4f4a2523e09 1044 Pfam PF02384 N-6 DNA Methylase 347 588 5.5E-13 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS09280 796fcc290d1badbdf67da4f4a2523e09 1044 SUPERFAMILY SSF53335 208 605 4.84E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS22230 b9657bce4a0f1f2c3ad38c94fc904f53 176 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 10 170 1.0E-80 T 29-03-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 THSYN_RS22230 b9657bce4a0f1f2c3ad38c94fc904f53 176 Pfam PF00994 Probable molybdopterin binding domain 16 157 3.7E-32 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS22230 b9657bce4a0f1f2c3ad38c94fc904f53 176 Gene3D G3DSA:3.40.980.10 10 170 1.2E-33 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS22230 b9657bce4a0f1f2c3ad38c94fc904f53 176 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 153 3.2E-35 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS22230 b9657bce4a0f1f2c3ad38c94fc904f53 176 PIRSF PIRSF006443 1 168 4.4E-62 T 29-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 THSYN_RS22230 b9657bce4a0f1f2c3ad38c94fc904f53 176 SUPERFAMILY SSF53218 10 171 7.33E-46 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS22230 b9657bce4a0f1f2c3ad38c94fc904f53 176 SMART SM00852 16 160 2.6E-32 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 SUPERFAMILY SSF56059 104 325 5.3E-65 T 29-03-2018 THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 Gene3D G3DSA:3.30.470.20 191 329 3.2E-58 T 29-03-2018 THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 29-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 423 3.5E-169 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 Gene3D G3DSA:3.40.50.20 2 86 4.3E-35 T 29-03-2018 THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 Gene3D G3DSA:3.90.600.10 330 424 7.3E-35 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 2.0E-34 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 Gene3D G3DSA:3.30.1490.20 87 189 7.1E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 SUPERFAMILY SSF52440 1 103 2.73E-35 T 29-03-2018 IPR016185 Pre-ATP-grasp domain THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 SMART SM01209 103 296 1.5E-132 T 29-03-2018 THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 296 1.1E-74 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 SMART SM01210 330 423 2.1E-52 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 SUPERFAMILY SSF51246 329 424 8.37E-32 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 423 42.187 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THSYN_RS01705 d3a8b2731680142cf9ae56a77326669c 427 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 331 421 2.2E-29 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THSYN_RS20225 fcbb80364857e0b709d4a795d61049ee 84 Pfam PF13711 Domain of unknown function (DUF4160) 9 73 1.0E-20 T 29-03-2018 IPR025427 Protein of unknown function DUF4160 THSYN_RS31850 c929efeed72647ba967c5680cb21d159 234 SMART SM00419 162 210 1.1E-7 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS31850 c929efeed72647ba967c5680cb21d159 234 Pfam PF00027 Cyclic nucleotide-binding domain 30 116 4.8E-17 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS31850 c929efeed72647ba967c5680cb21d159 234 SUPERFAMILY SSF46785 144 214 2.55E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS31850 c929efeed72647ba967c5680cb21d159 234 SUPERFAMILY SSF51206 3 143 4.19E-33 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like THSYN_RS31850 c929efeed72647ba967c5680cb21d159 234 Pfam PF13545 Crp-like helix-turn-helix domain 150 216 3.9E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS31850 c929efeed72647ba967c5680cb21d159 234 SMART SM00100 10 129 5.9E-18 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS31850 c929efeed72647ba967c5680cb21d159 234 Gene3D G3DSA:1.10.10.10 146 228 8.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS31850 c929efeed72647ba967c5680cb21d159 234 Gene3D G3DSA:2.60.120.10 1 145 5.2E-27 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 Pfam PF00512 His Kinase A (phospho-acceptor) domain 299 363 8.2E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 SMART SM00448 682 814 7.6E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 SUPERFAMILY SSF47384 286 365 1.47E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 SUPERFAMILY SSF52172 682 823 2.13E-36 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 Pfam PF00072 Response regulator receiver domain 684 751 2.4E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 Pfam PF00072 Response regulator receiver domain 773 814 4.5E-7 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 411 526 2.2E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 SMART SM00388 299 364 8.7E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 524 1.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 466 1.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 505 1.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 480 1.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 Gene3D G3DSA:3.30.565.10 368 532 5.4E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 Gene3D G3DSA:3.40.50.2300 536 672 7.8E-4 T 29-03-2018 THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 SUPERFAMILY SSF55874 353 524 3.14E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 Gene3D G3DSA:1.10.287.130 265 360 2.0E-18 T 29-03-2018 THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 SMART SM00387 411 529 4.2E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS26730 978bfc6f3e8409e5bb52b7b65c32fd9d 839 Gene3D G3DSA:3.40.50.2300 675 831 7.2E-40 T 29-03-2018 THSYN_RS14700 305945a69b641c6c9a0f575a0e7b649c 164 Pfam PF01899 Na+/H+ ion antiporter subunit 13 160 5.8E-44 T 29-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 THSYN_RS14700 305945a69b641c6c9a0f575a0e7b649c 164 PIRSF PIRSF019239 2 163 4.9E-42 T 29-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 THSYN_RS07545 a96c936568a4cdb7716227b9ad2b8853 432 Gene3D G3DSA:3.30.420.10 124 317 1.7E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS07545 a96c936568a4cdb7716227b9ad2b8853 432 SUPERFAMILY SSF53098 124 293 2.38E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS07545 a96c936568a4cdb7716227b9ad2b8853 432 Pfam PF13482 RNase_H superfamily 124 290 2.9E-29 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 Pfam PF00158 Sigma-54 interaction domain 146 309 3.1E-63 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 SMART SM00448 10 121 7.0E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 SUPERFAMILY SSF46689 403 459 7.62E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 423 440 1.2E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 440 460 1.2E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 Pfam PF00072 Response regulator receiver domain 12 121 1.5E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 Gene3D G3DSA:1.10.8.60 317 392 5.4E-19 T 29-03-2018 THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 SUPERFAMILY SSF52540 146 376 9.57E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 Pfam PF02954 Bacterial regulatory protein, Fis family 417 457 4.4E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 Gene3D G3DSA:3.40.50.2300 2 130 4.5E-34 T 29-03-2018 THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 SMART SM00382 164 307 4.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 230 245 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 Gene3D G3DSA:1.10.10.60 400 461 2.0E-11 T 29-03-2018 THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 SUPERFAMILY SSF52172 12 189 2.28E-40 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS11950 f731b4e9cdec8687bf4bf8f3599e6ccf 461 Gene3D G3DSA:3.40.50.300 142 315 1.7E-27 T 29-03-2018 THSYN_RS14390 8683b617e3913b8348d89cf1971ed693 130 ProSitePatterns PS00018 EF-hand calcium-binding domain. 41 53 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS14390 8683b617e3913b8348d89cf1971ed693 130 Pfam PF13202 EF hand 80 96 0.041 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS14390 8683b617e3913b8348d89cf1971ed693 130 Pfam PF13202 EF hand 37 55 1.0E-4 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS14390 8683b617e3913b8348d89cf1971ed693 130 ProSitePatterns PS00018 EF-hand calcium-binding domain. 84 96 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS14390 8683b617e3913b8348d89cf1971ed693 130 SUPERFAMILY SSF47473 37 97 2.68E-7 T 29-03-2018 IPR011992 EF-hand domain pair THSYN_RS14390 8683b617e3913b8348d89cf1971ed693 130 Gene3D G3DSA:1.10.238.10 50 85 2.9E-7 T 29-03-2018 THSYN_RS14390 8683b617e3913b8348d89cf1971ed693 130 Gene3D G3DSA:1.10.238.10 86 106 0.0047 T 29-03-2018 THSYN_RS14390 8683b617e3913b8348d89cf1971ed693 130 Gene3D G3DSA:1.10.238.10 16 49 0.0034 T 29-03-2018 THSYN_RS27640 e1a6d5390bd1b3afab43131465d407c5 292 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 9 278 8.3E-72 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 THSYN_RS27640 e1a6d5390bd1b3afab43131465d407c5 292 Gene3D G3DSA:3.30.70.890 165 282 2.0E-22 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain THSYN_RS27640 e1a6d5390bd1b3afab43131465d407c5 292 SUPERFAMILY SSF54211 10 160 4.93E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS27640 e1a6d5390bd1b3afab43131465d407c5 292 Gene3D G3DSA:3.30.230.10 8 163 4.1E-47 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS27640 e1a6d5390bd1b3afab43131465d407c5 292 Pfam PF00288 GHMP kinases N terminal domain 91 147 1.8E-11 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 THSYN_RS27640 e1a6d5390bd1b3afab43131465d407c5 292 Pfam PF08544 GHMP kinases C terminal 210 257 9.8E-7 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain THSYN_RS27640 e1a6d5390bd1b3afab43131465d407c5 292 SUPERFAMILY SSF55060 164 279 1.49E-28 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain THSYN_RS27640 e1a6d5390bd1b3afab43131465d407c5 292 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 8 274 30.904 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 THSYN_RS27640 e1a6d5390bd1b3afab43131465d407c5 292 PIRSF PIRSF010376 7 281 7.5E-80 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 THSYN_RS09720 0025b6a442dcf535e3d505604b03b724 1108 SUPERFAMILY SSF53474 234 409 1.26E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS09720 0025b6a442dcf535e3d505604b03b724 1108 Pfam PF07705 CARDB 967 1062 6.8E-7 T 29-03-2018 IPR011635 CARDB domain THSYN_RS09720 0025b6a442dcf535e3d505604b03b724 1108 Gene3D G3DSA:3.40.50.1820 233 494 1.3E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 SUPERFAMILY SSF55874 646 810 2.1E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 SMART SM00387 703 814 1.1E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 Pfam PF10114 Sensory domain found in PocR 397 558 3.3E-46 T 29-03-2018 IPR018771 PocR domain THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 703 813 1.2E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 Gene3D G3DSA:1.10.287.130 595 651 2.1E-22 T 29-03-2018 THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 Pfam PF00072 Response regulator receiver domain 841 965 1.3E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 Gene3D G3DSA:3.40.50.2300 830 979 6.2E-32 T 29-03-2018 THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 SMART SM00448 839 965 1.2E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 SMART SM01079 80 276 1.3E-68 T 29-03-2018 IPR006189 CHASE domain THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 Gene3D G3DSA:3.30.565.10 652 814 3.1E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 Pfam PF03924 CHASE domain 83 274 5.3E-57 T 29-03-2018 IPR006189 CHASE domain THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 SUPERFAMILY SSF52172 840 975 6.4E-29 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 SMART SM00388 591 657 2.1E-25 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 Pfam PF00512 His Kinase A (phospho-acceptor) domain 591 657 3.1E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 Gene3D G3DSA:3.30.450.20 409 594 1.5E-6 T 29-03-2018 THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 PRINTS PR00344 Bacterial sensor protein C-terminal signature 774 792 1.2E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 PRINTS PR00344 Bacterial sensor protein C-terminal signature 740 754 1.2E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 PRINTS PR00344 Bacterial sensor protein C-terminal signature 758 768 1.2E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 PRINTS PR00344 Bacterial sensor protein C-terminal signature 798 811 1.2E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27165 e0e07387683df19c7b3bf1523e9c5c7b 1058 SUPERFAMILY SSF47384 576 658 2.16E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS22595 c6799490613dfd838b201f21e654256d 127 SMART SM00530 21 78 9.1E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS22595 c6799490613dfd838b201f21e654256d 127 Pfam PF13560 Helix-turn-helix domain 17 72 9.1E-10 T 29-03-2018 THSYN_RS22595 c6799490613dfd838b201f21e654256d 127 Gene3D G3DSA:1.10.260.40 14 88 4.0E-16 T 29-03-2018 THSYN_RS22595 c6799490613dfd838b201f21e654256d 127 SUPERFAMILY SSF47413 14 84 7.6E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS17310 e29b4bb3287d434a2a17879a07aea535 96 SUPERFAMILY SSF52980 2 75 1.5E-5 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS17310 e29b4bb3287d434a2a17879a07aea535 96 Gene3D G3DSA:3.90.1570.10 2 85 1.1E-12 T 29-03-2018 THSYN_RS17310 e29b4bb3287d434a2a17879a07aea535 96 Pfam PF05685 Putative restriction endonuclease 20 75 6.9E-7 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS22825 104156f7cbbf92f1d17d7387df0571d0 612 SUPERFAMILY SSF142984 402 472 3.27E-13 T 29-03-2018 THSYN_RS22825 104156f7cbbf92f1d17d7387df0571d0 612 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 492 503 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS22825 104156f7cbbf92f1d17d7387df0571d0 612 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 209 378 2.1E-43 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS22825 104156f7cbbf92f1d17d7387df0571d0 612 SUPERFAMILY SSF140490 476 567 1.27E-27 T 29-03-2018 THSYN_RS22825 104156f7cbbf92f1d17d7387df0571d0 612 SUPERFAMILY SSF52833 21 176 5.48E-32 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS22825 104156f7cbbf92f1d17d7387df0571d0 612 SMART SM00928 479 524 2.7E-18 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS22825 104156f7cbbf92f1d17d7387df0571d0 612 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 328 343 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS22825 104156f7cbbf92f1d17d7387df0571d0 612 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 23 153 2.6E-26 T 29-03-2018 THSYN_RS22825 104156f7cbbf92f1d17d7387df0571d0 612 SUPERFAMILY SSF142019 193 399 2.48E-67 T 29-03-2018 THSYN_RS22825 104156f7cbbf92f1d17d7387df0571d0 612 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 480 562 8.2E-24 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS22825 104156f7cbbf92f1d17d7387df0571d0 612 Gene3D G3DSA:3.40.30.10 89 172 7.9E-6 T 29-03-2018 THSYN_RS09060 5c75e976dfc98d2bd96824a8f8f70ac4 279 Pfam PF00005 ABC transporter 29 181 4.9E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS09060 5c75e976dfc98d2bd96824a8f8f70ac4 279 SMART SM00382 38 229 1.3E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS09060 5c75e976dfc98d2bd96824a8f8f70ac4 279 SUPERFAMILY SSF52540 15 243 7.8E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09060 5c75e976dfc98d2bd96824a8f8f70ac4 279 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS09060 5c75e976dfc98d2bd96824a8f8f70ac4 279 Gene3D G3DSA:3.40.50.300 9 272 2.3E-64 T 29-03-2018 THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 SUPERFAMILY SSF55073 489 641 7.77E-45 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 66 184 1.4E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 197 319 4.9E-23 T 29-03-2018 IPR000014 PAS domain THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 Gene3D G3DSA:3.30.450.20 336 483 4.0E-22 T 29-03-2018 THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 SMART SM00091 198 264 8.9E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 SMART SM00091 67 133 2.0E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 SMART SM00091 324 392 270.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 SMART SM00267 473 642 2.7E-59 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 SUPERFAMILY SSF55785 67 170 2.09E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 SMART SM00086 398 441 5.4E-4 T 29-03-2018 IPR001610 PAC motif THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 SMART SM00086 270 312 1.4E-7 T 29-03-2018 IPR001610 PAC motif THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 480 641 3.8E-47 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 Pfam PF00990 Diguanylate cyclase, GGDEF domain 484 638 1.1E-43 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 SUPERFAMILY SSF55785 309 439 3.66E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 SUPERFAMILY SSF55785 212 321 2.09E-26 T 29-03-2018 IPR000014 PAS domain THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 Gene3D G3DSA:3.30.450.20 46 182 2.5E-22 T 29-03-2018 THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 Pfam PF08448 PAS fold 76 179 7.6E-7 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 Gene3D G3DSA:3.30.450.20 197 335 4.8E-30 T 29-03-2018 THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 Gene3D G3DSA:3.30.70.270 484 648 1.3E-55 T 29-03-2018 THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 Pfam PF08447 PAS fold 347 434 1.3E-13 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS01975 cf1543690bcc8fb4976a98e9a12bba18 649 Pfam PF08447 PAS fold 221 305 5.6E-15 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS24000 dfb60852109f89fbe68af2a3ed48dcf0 343 SUPERFAMILY SSF46589 17 104 6.28E-21 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 THSYN_RS24000 dfb60852109f89fbe68af2a3ed48dcf0 343 Gene3D G3DSA:3.30.930.10 12 343 9.5E-89 T 29-03-2018 THSYN_RS24000 dfb60852109f89fbe68af2a3ed48dcf0 343 SUPERFAMILY SSF55681 97 342 4.1E-83 T 29-03-2018 THSYN_RS24000 dfb60852109f89fbe68af2a3ed48dcf0 343 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 13 342 49.537 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 THSYN_RS24000 dfb60852109f89fbe68af2a3ed48dcf0 343 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 44 342 5.3E-103 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 THSYN_RS24000 dfb60852109f89fbe68af2a3ed48dcf0 343 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 25 92 3.5E-26 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 THSYN_RS24000 dfb60852109f89fbe68af2a3ed48dcf0 343 Pfam PF01409 tRNA synthetases class II core domain (F) 97 342 1.5E-104 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 THSYN_RS31355 067c59ff7841240842d1f40f721238f4 499 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 62 452 1.9E-37 T 29-03-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 THSYN_RS31355 067c59ff7841240842d1f40f721238f4 499 PIRSF PIRSF000163 52 491 7.5E-125 T 29-03-2018 IPR016209 Protochlorophyllide reductase, ChlB, light independent GO:0016730|GO:0046148|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31355 067c59ff7841240842d1f40f721238f4 499 TIGRFAM TIGR02015 BchY: chlorophyllide reductase subunit Y 52 469 3.1E-195 T 29-03-2018 IPR010245 Chlorophyllide reductase subunit Y GO:0015979|GO:0016021|GO:0016731|GO:0030494 THSYN_RS31355 067c59ff7841240842d1f40f721238f4 499 Gene3D G3DSA:3.40.50.1980 53 184 4.4E-14 T 29-03-2018 THSYN_RS31355 067c59ff7841240842d1f40f721238f4 499 Gene3D G3DSA:3.40.50.1980 185 325 1.9E-11 T 29-03-2018 THSYN_RS31355 067c59ff7841240842d1f40f721238f4 499 SUPERFAMILY SSF53807 53 462 3.92E-54 T 29-03-2018 THSYN_RS16715 399e83b0872ff4ee2ec6e5132365a580 243 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 16 242 37.105 T 29-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 THSYN_RS16715 399e83b0872ff4ee2ec6e5132365a580 243 Gene3D G3DSA:3.40.50.150 8 242 5.8E-44 T 29-03-2018 THSYN_RS16715 399e83b0872ff4ee2ec6e5132365a580 243 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 18 236 3.7E-77 T 29-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 THSYN_RS16715 399e83b0872ff4ee2ec6e5132365a580 243 Pfam PF13489 Methyltransferase domain 50 208 1.2E-21 T 29-03-2018 THSYN_RS16715 399e83b0872ff4ee2ec6e5132365a580 243 SUPERFAMILY SSF53335 11 224 7.28E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02875 a9c9420fc81b87c489dcfa1d068f7e8e 456 Pfam PF14706 Transposase DNA-binding 5 59 5.5E-20 T 29-03-2018 IPR014735 Transposase, Tn5-like, N-terminal THSYN_RS02875 a9c9420fc81b87c489dcfa1d068f7e8e 456 Gene3D G3DSA:3.90.350.10 60 342 5.6E-50 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS02875 a9c9420fc81b87c489dcfa1d068f7e8e 456 Gene3D G3DSA:1.10.246.40 4 59 1.1E-18 T 29-03-2018 THSYN_RS02875 a9c9420fc81b87c489dcfa1d068f7e8e 456 SUPERFAMILY SSF53098 5 448 4.93E-120 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS02875 a9c9420fc81b87c489dcfa1d068f7e8e 456 Pfam PF02281 Transposase Tn5 dimerisation domain 356 443 2.0E-19 T 29-03-2018 IPR003201 Transposase Tn5, dimerisation THSYN_RS02875 a9c9420fc81b87c489dcfa1d068f7e8e 456 Gene3D G3DSA:1.10.740.10 344 448 6.0E-36 T 29-03-2018 IPR014737 Transposase, Tn5-like, C-terminal THSYN_RS02875 a9c9420fc81b87c489dcfa1d068f7e8e 456 Pfam PF01609 Transposase DDE domain 263 349 1.6E-5 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS28650 a9c9420fc81b87c489dcfa1d068f7e8e 456 Pfam PF14706 Transposase DNA-binding 5 59 5.5E-20 T 29-03-2018 IPR014735 Transposase, Tn5-like, N-terminal THSYN_RS28650 a9c9420fc81b87c489dcfa1d068f7e8e 456 Gene3D G3DSA:3.90.350.10 60 342 5.6E-50 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS28650 a9c9420fc81b87c489dcfa1d068f7e8e 456 Gene3D G3DSA:1.10.246.40 4 59 1.1E-18 T 29-03-2018 THSYN_RS28650 a9c9420fc81b87c489dcfa1d068f7e8e 456 SUPERFAMILY SSF53098 5 448 4.93E-120 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS28650 a9c9420fc81b87c489dcfa1d068f7e8e 456 Pfam PF02281 Transposase Tn5 dimerisation domain 356 443 2.0E-19 T 29-03-2018 IPR003201 Transposase Tn5, dimerisation THSYN_RS28650 a9c9420fc81b87c489dcfa1d068f7e8e 456 Gene3D G3DSA:1.10.740.10 344 448 6.0E-36 T 29-03-2018 IPR014737 Transposase, Tn5-like, C-terminal THSYN_RS28650 a9c9420fc81b87c489dcfa1d068f7e8e 456 Pfam PF01609 Transposase DDE domain 263 349 1.6E-5 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS08620 37d72db599fa3a70fcd96fae79083f9d 221 Gene3D G3DSA:1.10.3890.10 4 204 9.7E-66 T 29-03-2018 IPR007451 Uncharacterised protein family UPF0274 THSYN_RS08620 37d72db599fa3a70fcd96fae79083f9d 221 Pfam PF04356 Protein of unknown function (DUF489) 7 196 1.9E-63 T 29-03-2018 IPR007451 Uncharacterised protein family UPF0274 THSYN_RS08620 37d72db599fa3a70fcd96fae79083f9d 221 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 11 190 1.0E-27 T 29-03-2018 IPR007451 Uncharacterised protein family UPF0274 THSYN_RS08620 37d72db599fa3a70fcd96fae79083f9d 221 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 204 29.947 T 29-03-2018 IPR007451 Uncharacterised protein family UPF0274 THSYN_RS08620 37d72db599fa3a70fcd96fae79083f9d 221 SUPERFAMILY SSF101322 2 205 7.72E-57 T 29-03-2018 IPR007451 Uncharacterised protein family UPF0274 THSYN_RS22260 75fbf93ee8d64eb1633535fa5f040f31 1046 SMART SM00028 630 663 13.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22260 75fbf93ee8d64eb1633535fa5f040f31 1046 SMART SM00028 790 823 49.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22260 75fbf93ee8d64eb1633535fa5f040f31 1046 SMART SM00028 750 783 84.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22260 75fbf93ee8d64eb1633535fa5f040f31 1046 SMART SM00028 710 743 5.5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22260 75fbf93ee8d64eb1633535fa5f040f31 1046 SMART SM00028 670 703 18.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22260 75fbf93ee8d64eb1633535fa5f040f31 1046 Gene3D G3DSA:1.10.10.10 306 414 3.2E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS22260 75fbf93ee8d64eb1633535fa5f040f31 1046 Gene3D G3DSA:1.25.40.10 621 900 1.7E-27 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22260 75fbf93ee8d64eb1633535fa5f040f31 1046 Gene3D G3DSA:3.40.50.300 35 305 1.5E-5 T 29-03-2018 THSYN_RS22260 75fbf93ee8d64eb1633535fa5f040f31 1046 Gene3D G3DSA:1.25.40.10 415 620 0.27 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22260 75fbf93ee8d64eb1633535fa5f040f31 1046 Pfam PF13424 Tetratricopeptide repeat 670 742 2.5E-8 T 29-03-2018 THSYN_RS22260 75fbf93ee8d64eb1633535fa5f040f31 1046 SUPERFAMILY SSF48452 625 829 5.18E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22260 75fbf93ee8d64eb1633535fa5f040f31 1046 SUPERFAMILY SSF52540 27 292 3.71E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 Gene3D G3DSA:1.10.287.110 1 120 1.3E-32 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 Pfam PF00226 DnaJ domain 5 66 1.4E-24 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 SUPERFAMILY SSF46565 1 110 7.2E-32 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 Gene3D G3DSA:1.20.5.460 292 311 1.3E-4 T 29-03-2018 THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 PRINTS PR00625 DnaJ domain signature 7 25 2.8E-23 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 PRINTS PR00625 DnaJ domain signature 41 61 2.8E-23 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 PRINTS PR00625 DnaJ domain signature 61 80 2.8E-23 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 PRINTS PR00625 DnaJ domain signature 25 40 2.8E-23 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 SUPERFAMILY SSF49493 215 295 4.84E-17 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 Pfam PF01556 DnaJ C terminal domain 134 286 3.9E-32 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 SMART SM00271 4 61 3.7E-26 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 Gene3D G3DSA:2.60.260.20 215 291 2.6E-16 T 29-03-2018 THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 SUPERFAMILY SSF49493 125 222 9.16E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THSYN_RS02410 0b000dfc45773acead811859edaa2ef3 314 Gene3D G3DSA:2.60.260.20 121 211 2.7E-18 T 29-03-2018 THSYN_RS12270 f8b903572b5d8100b0024dadf8dc63b3 478 SUPERFAMILY SSF47384 249 320 1.22E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS12270 f8b903572b5d8100b0024dadf8dc63b3 478 SMART SM00388 253 323 2.6E-4 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS12270 f8b903572b5d8100b0024dadf8dc63b3 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 1.5E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12270 f8b903572b5d8100b0024dadf8dc63b3 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 1.5E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12270 f8b903572b5d8100b0024dadf8dc63b3 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 1.5E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12270 f8b903572b5d8100b0024dadf8dc63b3 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 1.5E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12270 f8b903572b5d8100b0024dadf8dc63b3 478 SMART SM00387 365 472 8.9E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12270 f8b903572b5d8100b0024dadf8dc63b3 478 SUPERFAMILY SSF55874 311 471 4.58E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12270 f8b903572b5d8100b0024dadf8dc63b3 478 Pfam PF00512 His Kinase A (phospho-acceptor) domain 253 315 1.8E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS12270 f8b903572b5d8100b0024dadf8dc63b3 478 Gene3D G3DSA:1.10.287.130 241 319 4.5E-9 T 29-03-2018 THSYN_RS12270 f8b903572b5d8100b0024dadf8dc63b3 478 Gene3D G3DSA:3.30.565.10 323 478 5.3E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12270 f8b903572b5d8100b0024dadf8dc63b3 478 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 471 7.5E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS11675 e5a7c3c5bf9b6f6c9fb8c50f982a0944 301 SUPERFAMILY SSF53955 167 299 3.38E-45 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS11675 e5a7c3c5bf9b6f6c9fb8c50f982a0944 301 Pfam PF01464 Transglycosylase SLT domain 185 283 8.3E-28 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 THSYN_RS11675 e5a7c3c5bf9b6f6c9fb8c50f982a0944 301 Gene3D G3DSA:2.60.40.1180 43 158 2.2E-18 T 29-03-2018 THSYN_RS11675 e5a7c3c5bf9b6f6c9fb8c50f982a0944 301 Pfam PF08238 Sel1 repeat 102 132 6.7E-5 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS11675 e5a7c3c5bf9b6f6c9fb8c50f982a0944 301 Pfam PF08238 Sel1 repeat 75 99 1.0E-4 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS11675 e5a7c3c5bf9b6f6c9fb8c50f982a0944 301 SMART SM00671 101 136 7.4E-6 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS11675 e5a7c3c5bf9b6f6c9fb8c50f982a0944 301 SMART SM00671 65 100 0.001 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS11675 e5a7c3c5bf9b6f6c9fb8c50f982a0944 301 Gene3D G3DSA:1.10.530.10 166 301 2.4E-39 T 29-03-2018 THSYN_RS11675 e5a7c3c5bf9b6f6c9fb8c50f982a0944 301 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 202 230 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 THSYN_RS11675 e5a7c3c5bf9b6f6c9fb8c50f982a0944 301 SUPERFAMILY SSF81901 49 136 4.97E-14 T 29-03-2018 THSYN_RS07880 c9a79cdc92c0d8bacc6974d77834d4b5 165 Pfam PF00990 Diguanylate cyclase, GGDEF domain 25 160 3.6E-36 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS07880 c9a79cdc92c0d8bacc6974d77834d4b5 165 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 21 162 1.7E-40 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS07880 c9a79cdc92c0d8bacc6974d77834d4b5 165 SMART SM00267 9 164 2.2E-35 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS07880 c9a79cdc92c0d8bacc6974d77834d4b5 165 SUPERFAMILY SSF55073 23 162 1.88E-41 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS07880 c9a79cdc92c0d8bacc6974d77834d4b5 165 Gene3D G3DSA:3.30.70.270 19 164 4.7E-45 T 29-03-2018 THSYN_RS14750 bc200928fc2cddfd6818b44c07b6adb7 598 TIGRFAM TIGR02204 MsbA_rel: ABC transporter, permease/ATP-binding protein 16 590 1.6E-246 T 29-03-2018 IPR011918 ABC transporter, ATP-binding/permease protein THSYN_RS14750 bc200928fc2cddfd6818b44c07b6adb7 598 Gene3D G3DSA:1.20.1560.10 15 339 6.9E-64 T 29-03-2018 THSYN_RS14750 bc200928fc2cddfd6818b44c07b6adb7 598 SUPERFAMILY SSF90123 22 337 9.16E-74 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS14750 bc200928fc2cddfd6818b44c07b6adb7 598 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS14750 bc200928fc2cddfd6818b44c07b6adb7 598 SMART SM00382 379 565 3.9E-21 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS14750 bc200928fc2cddfd6818b44c07b6adb7 598 Gene3D G3DSA:3.40.50.300 349 586 1.1E-74 T 29-03-2018 THSYN_RS14750 bc200928fc2cddfd6818b44c07b6adb7 598 Pfam PF00005 ABC transporter 370 519 2.9E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS14750 bc200928fc2cddfd6818b44c07b6adb7 598 Pfam PF00664 ABC transporter transmembrane region 35 300 9.2E-51 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS14750 bc200928fc2cddfd6818b44c07b6adb7 598 SUPERFAMILY SSF52540 343 590 2.11E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10605 d0720cc0c6f0fd12df7f28be8d1220ad 160 SUPERFAMILY SSF55486 9 153 1.29E-38 T 29-03-2018 THSYN_RS10605 d0720cc0c6f0fd12df7f28be8d1220ad 160 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 4 151 21.508 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 THSYN_RS10605 d0720cc0c6f0fd12df7f28be8d1220ad 160 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 38 147 3.0E-29 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 THSYN_RS10605 d0720cc0c6f0fd12df7f28be8d1220ad 160 Pfam PF02130 Uncharacterized protein family UPF0054 24 144 2.0E-29 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 THSYN_RS10605 d0720cc0c6f0fd12df7f28be8d1220ad 160 Gene3D G3DSA:3.40.390.30 1 158 2.5E-40 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 THSYN_RS04275 3f82d94e444885c760c574bfcaf4300c 325 TIGRFAM TIGR01136 cysKM: cysteine synthase 10 314 8.3E-131 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 THSYN_RS04275 3f82d94e444885c760c574bfcaf4300c 325 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 THSYN_RS04275 3f82d94e444885c760c574bfcaf4300c 325 SUPERFAMILY SSF53686 6 314 2.88E-96 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THSYN_RS04275 3f82d94e444885c760c574bfcaf4300c 325 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 314 2.5E-136 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 THSYN_RS04275 3f82d94e444885c760c574bfcaf4300c 325 Gene3D G3DSA:3.40.50.1100 137 317 8.1E-59 T 29-03-2018 THSYN_RS04275 3f82d94e444885c760c574bfcaf4300c 325 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 303 1.3E-64 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THSYN_RS04275 3f82d94e444885c760c574bfcaf4300c 325 Gene3D G3DSA:3.40.50.1100 23 136 7.3E-32 T 29-03-2018 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 SMART SM00028 708 747 420.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 SMART SM00028 524 563 180.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 SMART SM00028 754 793 240.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 SMART SM00028 398 431 1.7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 SUPERFAMILY SSF48452 380 537 1.59E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 Gene3D G3DSA:1.20.5.1140 597 616 0.071 T 29-03-2018 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 Gene3D G3DSA:1.20.5.1140 506 526 1.9E-5 T 29-03-2018 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 Gene3D G3DSA:1.20.5.1140 690 711 5.8E-5 T 29-03-2018 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 Gene3D G3DSA:1.20.1250.10 759 834 7.6E-8 T 29-03-2018 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 Gene3D G3DSA:1.20.1250.10 527 596 3.8E-13 T 29-03-2018 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 Gene3D G3DSA:1.20.1250.10 617 689 2.3E-11 T 29-03-2018 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 Gene3D G3DSA:1.20.1250.10 442 505 1.5E-5 T 29-03-2018 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 Pfam PF13374 Tetratricopeptide repeat 523 566 5.3E-4 T 29-03-2018 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 Pfam PF13374 Tetratricopeptide repeat 707 737 0.012 T 29-03-2018 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 Pfam PF13374 Tetratricopeptide repeat 615 645 0.013 T 29-03-2018 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 Gene3D G3DSA:1.10.150.200 712 758 2.8E-9 T 29-03-2018 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 SUPERFAMILY SSF48452 497 636 1.4E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 Gene3D G3DSA:1.25.40.10 367 441 3.9E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00535 d6a661e21c75b17d815934b52442b350 879 SUPERFAMILY SSF48452 636 825 7.59E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23180 e5467806e52de8962f76d21fd2b396ef 590 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 24 189 1.1E-28 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THSYN_RS23180 e5467806e52de8962f76d21fd2b396ef 590 Gene3D G3DSA:3.40.50.1220 224 383 1.0E-21 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS23180 e5467806e52de8962f76d21fd2b396ef 590 SUPERFAMILY SSF52518 398 570 9.92E-12 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS23180 e5467806e52de8962f76d21fd2b396ef 590 PIRSF PIRSF004983 16 588 6.2E-129 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 THSYN_RS23180 e5467806e52de8962f76d21fd2b396ef 590 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 15 583 31.725 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 THSYN_RS23180 e5467806e52de8962f76d21fd2b396ef 590 SUPERFAMILY SSF52518 24 198 5.47E-33 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS23180 e5467806e52de8962f76d21fd2b396ef 590 Gene3D G3DSA:3.40.50.970 17 205 3.8E-50 T 29-03-2018 THSYN_RS23180 e5467806e52de8962f76d21fd2b396ef 590 Gene3D G3DSA:3.40.50.970 384 586 8.7E-17 T 29-03-2018 THSYN_RS23180 e5467806e52de8962f76d21fd2b396ef 590 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 21 462 1.1E-116 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 THSYN_RS01495 6e83bc72ac04c9d50f6645335a2e8f72 467 Pfam PF02913 FAD linked oxidases, C-terminal domain 223 463 1.8E-67 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THSYN_RS01495 6e83bc72ac04c9d50f6645335a2e8f72 467 Gene3D G3DSA:3.30.465.10 101 246 5.7E-36 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THSYN_RS01495 6e83bc72ac04c9d50f6645335a2e8f72 467 Pfam PF01565 FAD binding domain 48 186 8.6E-34 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THSYN_RS01495 6e83bc72ac04c9d50f6645335a2e8f72 467 Gene3D G3DSA:1.10.45.10 425 463 4.6E-15 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 THSYN_RS01495 6e83bc72ac04c9d50f6645335a2e8f72 467 SUPERFAMILY SSF55103 227 466 2.78E-67 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THSYN_RS01495 6e83bc72ac04c9d50f6645335a2e8f72 467 Gene3D G3DSA:3.30.43.10 2 100 5.7E-26 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THSYN_RS01495 6e83bc72ac04c9d50f6645335a2e8f72 467 SUPERFAMILY SSF56176 13 224 7.48E-65 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THSYN_RS20120 8a9aedf1394ed34a43677ca4c5b91559 472 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 109 4.2E-42 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THSYN_RS20120 8a9aedf1394ed34a43677ca4c5b91559 472 SUPERFAMILY SSF52440 1 112 1.01E-43 T 29-03-2018 IPR016185 Pre-ATP-grasp domain THSYN_RS20120 8a9aedf1394ed34a43677ca4c5b91559 472 SUPERFAMILY SSF51246 330 448 4.34E-43 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THSYN_RS20120 8a9aedf1394ed34a43677ca4c5b91559 472 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 321 2.9E-75 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THSYN_RS20120 8a9aedf1394ed34a43677ca4c5b91559 472 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THSYN_RS20120 8a9aedf1394ed34a43677ca4c5b91559 472 Gene3D G3DSA:3.40.50.20 1 122 3.8E-49 T 29-03-2018 THSYN_RS20120 8a9aedf1394ed34a43677ca4c5b91559 472 Pfam PF02785 Biotin carboxylase C-terminal domain 335 441 6.0E-40 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THSYN_RS20120 8a9aedf1394ed34a43677ca4c5b91559 472 SMART SM00878 335 441 1.3E-59 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THSYN_RS20120 8a9aedf1394ed34a43677ca4c5b91559 472 Gene3D G3DSA:3.30.1490.20 123 208 5.8E-21 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS20120 8a9aedf1394ed34a43677ca4c5b91559 472 SUPERFAMILY SSF56059 82 347 3.01E-67 T 29-03-2018 THSYN_RS20120 8a9aedf1394ed34a43677ca4c5b91559 472 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THSYN_RS20120 8a9aedf1394ed34a43677ca4c5b91559 472 Gene3D G3DSA:3.30.470.20 209 444 8.1E-99 T 29-03-2018 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1136 1150 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 Gene3D G3DSA:2.40.50.140 660 686 1.4E-6 T 29-03-2018 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 Pfam PF00400 WD domain, G-beta repeat 945 967 0.044 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 Pfam PF00400 WD domain, G-beta repeat 451 480 0.033 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 Pfam PF00400 WD domain, G-beta repeat 1115 1149 2.6E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 Pfam PF00400 WD domain, G-beta repeat 618 656 0.014 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 Pfam PF00400 WD domain, G-beta repeat 986 1017 9.3E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 Gene3D G3DSA:2.130.10.10 922 1093 9.5E-27 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SUPERFAMILY SSF50969 399 580 1.41E-31 T 29-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 Gene3D G3DSA:2.130.10.10 1094 1208 3.2E-17 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 643 657 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 Gene3D G3DSA:2.140.10.30 502 591 1.2E-14 T 29-03-2018 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 Gene3D G3DSA:2.80.10.50 592 659 2.0E-14 T 29-03-2018 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SUPERFAMILY SSF50998 1116 1162 7.85E-54 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SUPERFAMILY SSF50998 548 708 7.85E-54 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SUPERFAMILY SSF50998 932 1068 7.85E-54 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 Gene3D G3DSA:2.130.10.10 687 783 1.2E-5 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SMART SM00320 928 968 0.48 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SMART SM00320 978 1017 1.1E-6 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SMART SM00320 483 522 0.53 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SMART SM00320 1110 1149 4.7E-8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SMART SM00320 525 567 26.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SMART SM00320 617 656 1.0E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SMART SM00320 394 433 0.056 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SMART SM00320 659 696 1.6 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SMART SM00320 439 481 1.5E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 SMART SM00320 1068 1104 32.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS14140 e3fd896b0dda3c37b87dde307b83f3b8 1211 Gene3D G3DSA:2.130.10.120 259 501 1.4E-21 T 29-03-2018 THSYN_RS04440 0332162a90a788bf076bd66cf40f7f3e 96 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 20 90 1.7E-29 T 29-03-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 Gene3D G3DSA:2.160.20.10 302 453 8.8E-11 T 29-03-2018 IPR012334 Pectin lyase fold THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 SUPERFAMILY SSF51126 14 268 5.06E-25 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 Pfam PF13229 Right handed beta helix region 137 294 7.1E-15 T 29-03-2018 THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 Pfam PF13229 Right handed beta helix region 304 443 1.8E-8 T 29-03-2018 THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 Gene3D G3DSA:2.160.20.10 2 301 7.5E-30 T 29-03-2018 IPR012334 Pectin lyase fold THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 SUPERFAMILY SSF51126 252 438 8.16E-9 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 SMART SM00710 373 395 850.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 SMART SM00710 402 424 9900.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 SMART SM00710 321 343 1200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 SMART SM00710 119 143 370.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 SMART SM00710 165 187 1100.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 SMART SM00710 144 164 220.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 SMART SM00710 217 239 600.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS24720 fdfb36b11d5642fd98285c07f221fa9f 1591 SMART SM00710 247 269 3200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS12055 e9a5eadd5968e4239a0888fc910e547f 107 SUPERFAMILY SSF47413 7 68 2.16E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS12055 e9a5eadd5968e4239a0888fc910e547f 107 Gene3D G3DSA:1.10.260.40 1 88 1.8E-8 T 29-03-2018 THSYN_RS12055 e9a5eadd5968e4239a0888fc910e547f 107 SMART SM00530 16 69 0.003 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS12055 e9a5eadd5968e4239a0888fc910e547f 107 Pfam PF13560 Helix-turn-helix domain 13 67 8.2E-7 T 29-03-2018 THSYN_RS04575 ea6819b857813e82a5e18b55f0475356 519 Gene3D G3DSA:3.40.50.1460 173 424 2.9E-16 T 29-03-2018 THSYN_RS04575 ea6819b857813e82a5e18b55f0475356 519 Pfam PF12770 CHAT domain 114 412 1.1E-21 T 29-03-2018 IPR024983 CHAT domain THSYN_RS31635 54f866589d054cd36dd0d21a322dccca 211 Gene3D G3DSA:3.30.1380.20 39 211 8.6E-19 T 29-03-2018 THSYN_RS31635 54f866589d054cd36dd0d21a322dccca 211 TIGRFAM TIGR02019 BchJ: bacteriochlorophyll 4-vinyl reductase 19 206 1.1E-58 T 29-03-2018 IPR010249 Bacteriochlorophyll 4-vinyl reductase GO:0015979|GO:0030494 THSYN_RS31635 54f866589d054cd36dd0d21a322dccca 211 SMART SM00989 147 208 1.2E-11 T 29-03-2018 IPR004096 4-vinyl reductase, 4VR THSYN_RS31635 54f866589d054cd36dd0d21a322dccca 211 Pfam PF02830 V4R domain 154 207 1.3E-12 T 29-03-2018 IPR004096 4-vinyl reductase, 4VR THSYN_RS31635 54f866589d054cd36dd0d21a322dccca 211 SUPERFAMILY SSF111126 85 207 2.88E-21 T 29-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain THSYN_RS09115 cf96e26d718f2095c913c1b5083c9ec7 208 Pfam PF03458 UPF0126 domain 16 84 9.1E-16 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 THSYN_RS09115 cf96e26d718f2095c913c1b5083c9ec7 208 Pfam PF03458 UPF0126 domain 96 168 1.9E-18 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 THSYN_RS06045 bedbf9c94f342d5a52bb51110b60b412 1202 Pfam PF14579 Helix-hairpin-helix motif 804 892 7.6E-25 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS06045 bedbf9c94f342d5a52bb51110b60b412 1202 Gene3D G3DSA:2.40.50.140 988 1089 6.4E-16 T 29-03-2018 THSYN_RS06045 bedbf9c94f342d5a52bb51110b60b412 1202 SMART SM00481 6 73 4.8E-26 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal THSYN_RS06045 bedbf9c94f342d5a52bb51110b60b412 1202 Gene3D G3DSA:3.20.20.140 4 260 4.1E-41 T 29-03-2018 THSYN_RS06045 bedbf9c94f342d5a52bb51110b60b412 1202 Pfam PF02811 PHP domain 7 170 2.4E-42 T 29-03-2018 IPR004013 PHP domain GO:0003824 THSYN_RS06045 bedbf9c94f342d5a52bb51110b60b412 1202 Pfam PF01336 OB-fold nucleic acid binding domain 1012 1085 6.5E-8 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 THSYN_RS06045 bedbf9c94f342d5a52bb51110b60b412 1202 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 293 729 1.3E-176 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS06045 bedbf9c94f342d5a52bb51110b60b412 1202 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1047 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS06045 bedbf9c94f342d5a52bb51110b60b412 1202 Gene3D G3DSA:1.10.150.280 781 889 6.3E-8 T 29-03-2018 THSYN_RS06045 bedbf9c94f342d5a52bb51110b60b412 1202 SUPERFAMILY SSF89550 5 262 3.73E-22 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 THSYN_RS08325 466095d5374cd763482022432caf51ba 312 Gene3D G3DSA:3.40.50.300 1 246 4.9E-62 T 29-03-2018 THSYN_RS08325 466095d5374cd763482022432caf51ba 312 SMART SM00382 30 215 3.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS08325 466095d5374cd763482022432caf51ba 312 Pfam PF00005 ABC transporter 21 165 5.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS08325 466095d5374cd763482022432caf51ba 312 SUPERFAMILY SSF52540 4 232 5.44E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08325 466095d5374cd763482022432caf51ba 312 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS05490 06fe34cc666e2b370f6185095e38a836 654 Gene3D G3DSA:3.40.50.300 414 638 1.1E-25 T 29-03-2018 THSYN_RS05490 06fe34cc666e2b370f6185095e38a836 654 SUPERFAMILY SSF52540 396 427 8.69E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05490 06fe34cc666e2b370f6185095e38a836 654 SUPERFAMILY SSF52540 479 650 8.69E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05490 06fe34cc666e2b370f6185095e38a836 654 SUPERFAMILY SSF52540 320 360 8.69E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05490 06fe34cc666e2b370f6185095e38a836 654 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 38 647 47.783 T 29-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 THSYN_RS05490 06fe34cc666e2b370f6185095e38a836 654 Pfam PF13538 UvrD-like helicase C-terminal domain 578 625 2.4E-16 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain THSYN_RS05490 06fe34cc666e2b370f6185095e38a836 654 Gene3D G3DSA:3.40.50.300 140 375 7.2E-43 T 29-03-2018 THSYN_RS05490 06fe34cc666e2b370f6185095e38a836 654 SUPERFAMILY SSF52540 180 360 1.01E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05490 06fe34cc666e2b370f6185095e38a836 654 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 30 647 4.8E-147 T 29-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 THSYN_RS05490 06fe34cc666e2b370f6185095e38a836 654 Pfam PF13245 AAA domain 187 343 2.5E-26 T 29-03-2018 THSYN_RS25020 d7a603c6eb7132816c64627dbd023686 75 Gene3D G3DSA:1.10.260.40 11 74 4.9E-10 T 29-03-2018 THSYN_RS25020 d7a603c6eb7132816c64627dbd023686 75 SMART SM00530 19 72 7.8E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS25020 d7a603c6eb7132816c64627dbd023686 75 Pfam PF01381 Helix-turn-helix 20 70 2.1E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS25020 d7a603c6eb7132816c64627dbd023686 75 SUPERFAMILY SSF47413 18 73 4.5E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS22695 01573cd29c91217d5dc3cc6fe68e8512 356 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 234 245 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS22695 01573cd29c91217d5dc3cc6fe68e8512 356 SUPERFAMILY SSF54862 165 246 4.81E-8 T 29-03-2018 THSYN_RS22695 01573cd29c91217d5dc3cc6fe68e8512 356 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 120 335 7.3E-23 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS22695 01573cd29c91217d5dc3cc6fe68e8512 356 Gene3D G3DSA:3.30.413.10 48 345 8.5E-26 T 29-03-2018 THSYN_RS22695 01573cd29c91217d5dc3cc6fe68e8512 356 SUPERFAMILY SSF55124 7 124 2.47E-40 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS22695 01573cd29c91217d5dc3cc6fe68e8512 356 SUPERFAMILY SSF56014 253 343 1.07E-31 T 29-03-2018 THSYN_RS22695 01573cd29c91217d5dc3cc6fe68e8512 356 SUPERFAMILY SSF56014 120 189 1.07E-31 T 29-03-2018 THSYN_RS22695 01573cd29c91217d5dc3cc6fe68e8512 356 TIGRFAM TIGR02066 dsrB: sulfite reductase, dissimilatory-type beta subunit 22 356 1.8E-165 T 29-03-2018 IPR011808 Sulphite reductase, dissimilatory-type beta subunit GO:0006790|GO:0009055|GO:0018551|GO:0051539 KEGG: 00633+1.8.99.5|KEGG: 00920+1.8.99.5|MetaCyc: PWY-5306|MetaCyc: PWY-5360 THSYN_RS22695 01573cd29c91217d5dc3cc6fe68e8512 356 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 50 110 2.7E-6 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS25875 292ee10fb3779a2c0e0aaee5e7be1248 144 SMART SM00448 4 128 4.2E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS25875 292ee10fb3779a2c0e0aaee5e7be1248 144 Pfam PF00072 Response regulator receiver domain 6 128 4.4E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS25875 292ee10fb3779a2c0e0aaee5e7be1248 144 SUPERFAMILY SSF52172 2 131 2.42E-30 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS25875 292ee10fb3779a2c0e0aaee5e7be1248 144 Gene3D G3DSA:3.40.50.2300 1 133 5.9E-28 T 29-03-2018 THSYN_RS07410 3f47db0f059ea9897e7d4579ee980d41 228 Pfam PF01726 LexA DNA binding domain 4 66 1.0E-23 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 THSYN_RS07410 3f47db0f059ea9897e7d4579ee980d41 228 TIGRFAM TIGR00498 lexA: repressor LexA 4 219 4.3E-64 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 THSYN_RS07410 3f47db0f059ea9897e7d4579ee980d41 228 Gene3D G3DSA:2.10.109.10 99 220 1.6E-22 T 29-03-2018 THSYN_RS07410 3f47db0f059ea9897e7d4579ee980d41 228 Pfam PF00717 Peptidase S24-like 133 195 7.6E-13 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THSYN_RS07410 3f47db0f059ea9897e7d4579ee980d41 228 Hamap MF_00015 LexA repressor [lexA]. 4 221 30.99 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 THSYN_RS07410 3f47db0f059ea9897e7d4579ee980d41 228 Gene3D G3DSA:1.10.10.10 1 71 3.9E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07410 3f47db0f059ea9897e7d4579ee980d41 228 SUPERFAMILY SSF51306 94 219 4.19E-34 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THSYN_RS07410 3f47db0f059ea9897e7d4579ee980d41 228 SUPERFAMILY SSF46785 4 70 4.31E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07410 3f47db0f059ea9897e7d4579ee980d41 228 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 130 140 5.4E-12 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THSYN_RS07410 3f47db0f059ea9897e7d4579ee980d41 228 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 169 181 5.4E-12 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THSYN_RS07410 3f47db0f059ea9897e7d4579ee980d41 228 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 141 152 5.4E-12 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 503 615 3.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 Gene3D G3DSA:3.30.450.20 81 213 4.8E-8 T 29-03-2018 THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 SUPERFAMILY SSF52172 653 769 2.49E-9 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 Gene3D G3DSA:1.10.287.130 379 451 1.4E-18 T 29-03-2018 THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 Gene3D G3DSA:3.30.565.10 459 625 2.5E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 Pfam PF00512 His Kinase A (phospho-acceptor) domain 389 455 1.8E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 SMART SM00387 502 616 4.7E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 Gene3D G3DSA:3.40.50.2300 634 773 6.3E-12 T 29-03-2018 THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 SUPERFAMILY SSF47384 376 456 9.22E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 SUPERFAMILY SSF55874 444 616 1.96E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 PRINTS PR00344 Bacterial sensor protein C-terminal signature 600 613 3.5E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 594 3.5E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 PRINTS PR00344 Bacterial sensor protein C-terminal signature 559 569 3.5E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 555 3.5E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07315 cef7a162b03c60b0912b3c136c38e0c4 780 SMART SM00388 388 455 1.2E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS12750 a45ee1382b8af674edc2b06f9897d875 534 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 60 475 1.6E-71 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 THSYN_RS12750 a45ee1382b8af674edc2b06f9897d875 534 SUPERFAMILY SSF56317 222 506 1.07E-29 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THSYN_RS12750 a45ee1382b8af674edc2b06f9897d875 534 Pfam PF00795 Carbon-nitrogen hydrolase 226 494 1.5E-18 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THSYN_RS12750 a45ee1382b8af674edc2b06f9897d875 534 Gene3D G3DSA:3.60.110.10 221 500 2.6E-29 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THSYN_RS12750 a45ee1382b8af674edc2b06f9897d875 534 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 7 513 14.867 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 THSYN_RS16735 5fdb74ef11a92444a45a5da797b06b9c 90 Gene3D G3DSA:1.10.10.10 10 71 4.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS16735 5fdb74ef11a92444a45a5da797b06b9c 90 SUPERFAMILY SSF46689 5 69 3.58E-21 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS16735 5fdb74ef11a92444a45a5da797b06b9c 90 Pfam PF04255 Protein of unknown function (DUF433) 10 64 4.8E-24 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS03330 9033f0818a01836837005c74b4f29885 316 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 284 9.4E-99 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 THSYN_RS03330 9033f0818a01836837005c74b4f29885 316 Pfam PF02401 LytB protein 3 282 2.3E-89 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 THSYN_RS03330 9033f0818a01836837005c74b4f29885 316 Gene3D G3DSA:3.10.180.10 81 197 0.0084 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THSYN_RS03330 9033f0818a01836837005c74b4f29885 316 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 286 37.712 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 THSYN_RS03330 9033f0818a01836837005c74b4f29885 316 Gene3D G3DSA:3.40.50.1220 198 299 0.0027 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS24775 cda63b753f27fd3cce74a34472256225 495 Pfam PF10531 SLBB domain 289 336 1.7E-14 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24775 cda63b753f27fd3cce74a34472256225 495 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 408 419 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS24775 cda63b753f27fd3cce74a34472256225 495 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 495 159.191 T 29-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 THSYN_RS24775 cda63b753f27fd3cce74a34472256225 495 Gene3D G3DSA:3.30.70.20 346 379 9.9E-4 T 29-03-2018 THSYN_RS24775 cda63b753f27fd3cce74a34472256225 495 Gene3D G3DSA:3.30.70.20 412 484 6.7E-5 T 29-03-2018 THSYN_RS24775 cda63b753f27fd3cce74a34472256225 495 Gene3D G3DSA:3.30.70.20 380 411 2.0E-7 T 29-03-2018 THSYN_RS24775 cda63b753f27fd3cce74a34472256225 495 Pfam PF12838 4Fe-4S dicluster domain 368 421 4.6E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS24775 cda63b753f27fd3cce74a34472256225 495 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 3 437 2.1E-174 T 29-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 THSYN_RS24775 cda63b753f27fd3cce74a34472256225 495 SUPERFAMILY SSF46548 330 440 7.5E-20 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS24775 cda63b753f27fd3cce74a34472256225 495 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 131 276 2.2E-48 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24775 cda63b753f27fd3cce74a34472256225 495 SUPERFAMILY SSF142019 86 296 6.15E-57 T 29-03-2018 THSYN_RS24775 cda63b753f27fd3cce74a34472256225 495 Pfam PF13375 RnfC Barrel sandwich hybrid domain 5 106 3.6E-30 T 29-03-2018 IPR026902 RnfC Barrel sandwich hybrid domain THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:2.140.10.10 515 591 1.5E-24 T 29-03-2018 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 518 569 2.7E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 126 165 3.2E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 188 223 0.05 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 266 305 6.6E-9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 45 82 0.0035 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 434 473 3.8E-13 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 85 123 1.2E-9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 308 346 1.0E-9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 349 388 8.0E-9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 391 431 3.6E-10 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 476 515 1.3E-13 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 610 646 5.2E-9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 226 263 0.026 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SMART SM00320 572 607 3.5E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:2.80.10.50 330 383 2.2E-23 T 29-03-2018 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:2.60.40.10 716 807 0.27 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 PRINTS PR00320 G protein beta WD-40 repeat signature 460 474 6.1E-7 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 PRINTS PR00320 G protein beta WD-40 repeat signature 502 516 6.1E-7 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 PRINTS PR00320 G protein beta WD-40 repeat signature 594 608 6.1E-7 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:2.60.40.10 820 908 0.44 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 418 432 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:2.40.10.120 618 659 7.6E-12 T 29-03-2018 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SUPERFAMILY SSF50978 201 517 1.37E-100 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:3.40.50.300 1139 1282 3.1E-6 T 29-03-2018 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 594 608 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SUPERFAMILY SSF52540 1153 1361 3.17E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:1.10.10.670 305 329 1.4E-15 T 29-03-2018 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:1.10.10.670 384 407 2.2E-11 T 29-03-2018 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SUPERFAMILY SSF50960 490 671 3.27E-45 T 29-03-2018 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 271 305 1.1E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 480 515 3.0E-10 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 89 123 2.1E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 312 346 4.3E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 438 473 2.9E-10 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 586 607 6.0E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 614 646 3.0E-6 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 200 223 0.0053 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 352 379 9.2E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 142 165 3.9E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 58 82 0.0056 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 395 431 2.5E-9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 238 262 0.0091 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Pfam PF00400 WD domain, G-beta repeat 542 569 3.7E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:2.40.50.140 471 514 2.1E-23 T 29-03-2018 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:2.40.50.140 434 470 1.8E-21 T 29-03-2018 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:2.130.10.10 214 304 6.5E-33 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 SUPERFAMILY SSF50969 53 267 3.84E-47 T 29-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:2.80.10.50 155 213 5.3E-16 T 29-03-2018 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:2.130.10.120 38 154 1.8E-32 T 29-03-2018 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:2.80.10.50 592 617 9.3E-12 T 29-03-2018 THSYN_RS16400 645d5771a72826bbf1808abefa18c5b7 1493 Gene3D G3DSA:2.80.10.50 408 433 1.8E-16 T 29-03-2018 THSYN_RS02045 c79be39bfde9c55db14fad9a11107e93 233 Pfam PF07475 HPr Serine kinase C-terminal domain 133 213 2.9E-30 T 29-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 THSYN_RS02045 c79be39bfde9c55db14fad9a11107e93 233 Gene3D G3DSA:3.40.50.300 136 217 6.7E-17 T 29-03-2018 THSYN_RS02045 c79be39bfde9c55db14fad9a11107e93 233 Pfam PF02603 HPr Serine kinase N terminus 5 130 1.3E-22 T 29-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 THSYN_RS02045 c79be39bfde9c55db14fad9a11107e93 233 Gene3D G3DSA:3.40.1390.20 4 135 7.6E-28 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like THSYN_RS02045 c79be39bfde9c55db14fad9a11107e93 233 SUPERFAMILY SSF75138 15 133 1.12E-22 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like THSYN_RS02045 c79be39bfde9c55db14fad9a11107e93 233 SUPERFAMILY SSF53795 135 231 4.27E-15 T 29-03-2018 THSYN_RS15100 8d24eb1fd9e9eba3e18b6f8e37305396 293 PIRSF PIRSF005295 2 260 1.1E-97 T 29-03-2018 IPR012022 Protein of unknown function UCP005295 THSYN_RS15100 8d24eb1fd9e9eba3e18b6f8e37305396 293 SUPERFAMILY SSF51556 2 256 1.31E-49 T 29-03-2018 IPR032466 Metal-dependent hydrolase THSYN_RS15100 8d24eb1fd9e9eba3e18b6f8e37305396 293 Pfam PF01026 TatD related DNase 4 226 6.4E-15 T 29-03-2018 IPR001130 TatD family GO:0016788 THSYN_RS15100 8d24eb1fd9e9eba3e18b6f8e37305396 293 Gene3D G3DSA:3.20.20.140 2 269 1.0E-35 T 29-03-2018 THSYN_RS09575 d844bb300f2f29e9177bc8dda10979dd 111 PIRSF PIRSF006223 2 109 9.0E-25 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE THSYN_RS09575 d844bb300f2f29e9177bc8dda10979dd 111 Pfam PF04358 DsrC like protein 11 105 1.6E-26 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE THSYN_RS09575 d844bb300f2f29e9177bc8dda10979dd 111 Gene3D G3DSA:3.30.1420.10 5 39 1.7E-8 T 29-03-2018 THSYN_RS09575 d844bb300f2f29e9177bc8dda10979dd 111 Gene3D G3DSA:1.10.10.370 40 108 7.9E-18 T 29-03-2018 THSYN_RS09575 d844bb300f2f29e9177bc8dda10979dd 111 SUPERFAMILY SSF69721 10 105 4.58E-25 T 29-03-2018 IPR025526 DsrC-like domain THSYN_RS09575 d844bb300f2f29e9177bc8dda10979dd 111 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 10 105 5.1E-25 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 Pfam PF01588 Putative tRNA binding domain 601 693 3.5E-24 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 Gene3D G3DSA:1.10.730.10 376 540 1.4E-30 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 PRINTS PR01041 Methionyl-tRNA synthetase signature 250 261 8.2E-24 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 PRINTS PR01041 Methionyl-tRNA synthetase signature 41 55 8.2E-24 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 PRINTS PR01041 Methionyl-tRNA synthetase signature 387 398 8.2E-24 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 PRINTS PR01041 Methionyl-tRNA synthetase signature 9 22 8.2E-24 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 8.2E-24 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 PRINTS PR01041 Methionyl-tRNA synthetase signature 294 309 8.2E-24 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 Gene3D G3DSA:3.40.50.620 3 74 2.7E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 SUPERFAMILY SSF57770 141 175 1.22E-11 T 29-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 7 538 1.2E-170 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 580 696 5.6E-42 T 29-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 SUPERFAMILY SSF50249 590 695 1.62E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 SUPERFAMILY SSF47323 393 551 2.62E-39 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 25 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 Pfam PF09334 tRNA synthetases class I (M) 7 399 1.8E-153 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 SUPERFAMILY SSF52374 175 389 2.35E-98 T 29-03-2018 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 SUPERFAMILY SSF52374 4 140 2.35E-98 T 29-03-2018 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 Hamap MF_00098 Methionine--tRNA ligase [metG]. 5 549 39.666 T 29-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 Gene3D G3DSA:2.20.28.20 141 164 2.6E-15 T 29-03-2018 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 Gene3D G3DSA:2.170.220.10 165 249 2.2E-19 T 29-03-2018 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 Gene3D G3DSA:2.40.50.140 587 696 1.1E-28 T 29-03-2018 THSYN_RS05865 7735af01dae26bf97a822ccce4e82166 696 Gene3D G3DSA:3.40.50.620 250 374 4.0E-21 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS15670 c462dcc33a5ec17a2f746f14a67e40d6 86 Gene3D G3DSA:3.60.60.10 1 86 9.7E-6 T 29-03-2018 THSYN_RS02065 6aa904447f45682e14287b77aaeb34b8 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 4 241 1.8E-113 T 29-03-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 THSYN_RS02065 6aa904447f45682e14287b77aaeb34b8 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS02065 6aa904447f45682e14287b77aaeb34b8 241 SMART SM00382 28 222 9.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS02065 6aa904447f45682e14287b77aaeb34b8 241 Pfam PF00005 ABC transporter 19 166 3.0E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS02065 6aa904447f45682e14287b77aaeb34b8 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 215 236 4.5E-6 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal THSYN_RS02065 6aa904447f45682e14287b77aaeb34b8 241 SUPERFAMILY SSF52540 4 236 5.44E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02065 6aa904447f45682e14287b77aaeb34b8 241 Gene3D G3DSA:3.40.50.300 1 235 1.7E-59 T 29-03-2018 THSYN_RS17960 5b2895ee151a2399c469422a740ff228 336 Gene3D G3DSA:1.10.10.60 199 256 8.3E-8 T 29-03-2018 THSYN_RS17960 5b2895ee151a2399c469422a740ff228 336 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 209 250 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THSYN_RS17960 5b2895ee151a2399c469422a740ff228 336 SMART SM00342 221 307 1.6E-14 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THSYN_RS17960 5b2895ee151a2399c469422a740ff228 336 Gene3D G3DSA:1.10.10.60 257 309 6.8E-7 T 29-03-2018 THSYN_RS17960 5b2895ee151a2399c469422a740ff228 336 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 258 303 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THSYN_RS17960 5b2895ee151a2399c469422a740ff228 336 Pfam PF12833 Helix-turn-helix domain 227 309 3.1E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SUPERFAMILY SSF48452 31 196 1.07E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Gene3D G3DSA:1.25.40.10 272 357 1.7E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Gene3D G3DSA:1.25.40.10 840 887 1.4E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Gene3D G3DSA:1.25.40.10 364 461 9.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Gene3D G3DSA:1.25.40.10 695 839 2.4E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SUPERFAMILY SSF48452 374 605 6.51E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Gene3D G3DSA:1.25.20.10 888 929 0.065 T 29-03-2018 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Pfam PF13428 Tetratricopeptide repeat 613 655 5.6E-5 T 29-03-2018 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Gene3D G3DSA:1.25.40.10 462 544 5.5E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Pfam PF13429 Tetratricopeptide repeat 784 904 3.0E-7 T 29-03-2018 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Gene3D G3DSA:1.25.40.10 221 271 9.2E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 TIGRFAM TIGR02917 PEP_TPR_lipo: putative PEP-CTERM system TPR-repeat lipoprotein 22 911 3.0E-146 T 29-03-2018 IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SUPERFAMILY SSF48452 624 912 2.09E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Gene3D G3DSA:1.25.40.10 27 126 2.1E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Gene3D G3DSA:1.25.40.10 127 220 2.0E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SUPERFAMILY SSF81901 139 348 2.28E-20 T 29-03-2018 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Gene3D G3DSA:1.25.40.10 545 591 3.6E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Pfam PF13432 Tetratricopeptide repeat 38 97 0.0028 T 29-03-2018 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Pfam PF13432 Tetratricopeptide repeat 210 272 7.7E-5 T 29-03-2018 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Pfam PF13432 Tetratricopeptide repeat 482 544 8.7E-7 T 29-03-2018 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Pfam PF13432 Tetratricopeptide repeat 277 340 7.2E-10 T 29-03-2018 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Pfam PF13432 Tetratricopeptide repeat 143 203 0.013 T 29-03-2018 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 Gene3D G3DSA:1.25.40.10 592 694 2.2E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SMART SM00028 511 544 43.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SMART SM00028 273 306 310.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SMART SM00028 375 408 420.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SMART SM00028 647 680 41.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SMART SM00028 205 238 32.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SMART SM00028 137 170 0.006 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SMART SM00028 850 883 74.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SMART SM00028 545 578 430.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SMART SM00028 783 816 21.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SMART SM00028 477 510 0.053 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SMART SM00028 239 272 38.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SMART SM00028 307 340 0.25 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14915 9f30f867d84d2a497b5a2cc17cda9476 930 SMART SM00028 817 849 33.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS18280 65016f3f70f43f6b92e3e77b1d854569 394 Pfam PF01609 Transposase DDE domain 108 343 9.7E-23 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS18280 65016f3f70f43f6b92e3e77b1d854569 394 Gene3D G3DSA:3.90.350.10 113 330 1.7E-4 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS18280 65016f3f70f43f6b92e3e77b1d854569 394 Pfam PF13808 DDE_Tnp_1-associated 13 98 8.6E-31 T 29-03-2018 IPR032806 H repeat-associated protein, N-terminal THSYN_RS28520 65016f3f70f43f6b92e3e77b1d854569 394 Pfam PF01609 Transposase DDE domain 108 343 9.7E-23 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS28520 65016f3f70f43f6b92e3e77b1d854569 394 Gene3D G3DSA:3.90.350.10 113 330 1.7E-4 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS28520 65016f3f70f43f6b92e3e77b1d854569 394 Pfam PF13808 DDE_Tnp_1-associated 13 98 8.6E-31 T 29-03-2018 IPR032806 H repeat-associated protein, N-terminal THSYN_RS33240 65016f3f70f43f6b92e3e77b1d854569 394 Pfam PF01609 Transposase DDE domain 108 343 9.7E-23 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS33240 65016f3f70f43f6b92e3e77b1d854569 394 Gene3D G3DSA:3.90.350.10 113 330 1.7E-4 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS33240 65016f3f70f43f6b92e3e77b1d854569 394 Pfam PF13808 DDE_Tnp_1-associated 13 98 8.6E-31 T 29-03-2018 IPR032806 H repeat-associated protein, N-terminal THSYN_RS01985 65016f3f70f43f6b92e3e77b1d854569 394 Pfam PF01609 Transposase DDE domain 108 343 9.7E-23 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS01985 65016f3f70f43f6b92e3e77b1d854569 394 Gene3D G3DSA:3.90.350.10 113 330 1.7E-4 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS01985 65016f3f70f43f6b92e3e77b1d854569 394 Pfam PF13808 DDE_Tnp_1-associated 13 98 8.6E-31 T 29-03-2018 IPR032806 H repeat-associated protein, N-terminal THSYN_RS18845 40bd71d94544095dd85d341161aac34a 72 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 46 59 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 THSYN_RS18845 40bd71d94544095dd85d341161aac34a 72 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 1 72 20.301 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 THSYN_RS18845 40bd71d94544095dd85d341161aac34a 72 Pfam PF00741 Gas vesicle protein 12 50 1.7E-16 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 THSYN_RS18845 40bd71d94544095dd85d341161aac34a 72 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 13 27 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 THSYN_RS11925 40bd71d94544095dd85d341161aac34a 72 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 46 59 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 THSYN_RS11925 40bd71d94544095dd85d341161aac34a 72 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 1 72 20.301 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 THSYN_RS11925 40bd71d94544095dd85d341161aac34a 72 Pfam PF00741 Gas vesicle protein 12 50 1.7E-16 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 THSYN_RS11925 40bd71d94544095dd85d341161aac34a 72 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 13 27 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 THSYN_RS15395 40bd71d94544095dd85d341161aac34a 72 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 46 59 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 THSYN_RS15395 40bd71d94544095dd85d341161aac34a 72 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 1 72 20.301 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 THSYN_RS15395 40bd71d94544095dd85d341161aac34a 72 Pfam PF00741 Gas vesicle protein 12 50 1.7E-16 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 THSYN_RS15395 40bd71d94544095dd85d341161aac34a 72 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 13 27 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 THSYN_RS14910 29efe36f0a8cff1761aa8a81253ede71 342 SUPERFAMILY SSF102114 102 298 2.35E-9 T 29-03-2018 THSYN_RS14910 29efe36f0a8cff1761aa8a81253ede71 342 PIRSF PIRSF006004 3 341 9.9E-84 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS14910 29efe36f0a8cff1761aa8a81253ede71 342 Gene3D G3DSA:3.20.20.70 24 334 4.1E-21 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS14910 29efe36f0a8cff1761aa8a81253ede71 342 Pfam PF04055 Radical SAM superfamily 106 263 1.2E-7 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS26570 eb89b247acfe18dec74e1cca3cdb80a9 128 Gene3D G3DSA:3.90.1010.10 1 127 6.1E-52 T 29-03-2018 THSYN_RS26570 eb89b247acfe18dec74e1cca3cdb80a9 128 Pfam PF01592 NifU-like N terminal domain 2 126 4.3E-57 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 THSYN_RS26570 eb89b247acfe18dec74e1cca3cdb80a9 128 SUPERFAMILY SSF82649 1 125 1.78E-48 T 29-03-2018 THSYN_RS26570 eb89b247acfe18dec74e1cca3cdb80a9 128 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 6.5E-68 T 29-03-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 THSYN_RS28150 d457b0831b5b9fabb5fb6e5694d10cd5 231 Pfam PF04055 Radical SAM superfamily 44 187 1.1E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS28150 d457b0831b5b9fabb5fb6e5694d10cd5 231 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 26 202 1.8E-55 T 29-03-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein THSYN_RS28150 d457b0831b5b9fabb5fb6e5694d10cd5 231 SUPERFAMILY SSF102114 40 213 7.85E-28 T 29-03-2018 THSYN_RS28150 d457b0831b5b9fabb5fb6e5694d10cd5 231 Pfam PF13353 4Fe-4S single cluster domain 38 115 3.7E-8 T 29-03-2018 THSYN_RS28150 d457b0831b5b9fabb5fb6e5694d10cd5 231 Gene3D G3DSA:3.20.20.70 37 217 1.7E-27 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS25960 1f1e15d8938070106b62e1fbcafa3e94 200 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 THSYN_RS25960 1f1e15d8938070106b62e1fbcafa3e94 200 Gene3D G3DSA:3.40.50.360 2 198 4.3E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain THSYN_RS25960 1f1e15d8938070106b62e1fbcafa3e94 200 SUPERFAMILY SSF52218 3 194 4.98E-59 T 29-03-2018 IPR029039 Flavoprotein-like domain THSYN_RS25960 1f1e15d8938070106b62e1fbcafa3e94 200 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 4 192 1.0E-40 T 29-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 THSYN_RS25960 1f1e15d8938070106b62e1fbcafa3e94 200 Pfam PF03358 NADPH-dependent FMN reductase 12 141 1.7E-7 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 THSYN_RS10015 9612c6c377d2a176c4a7e8d682eed3c8 1445 SUPERFAMILY SSF103088 1333 1444 5.49E-18 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS10015 9612c6c377d2a176c4a7e8d682eed3c8 1445 Pfam PF00691 OmpA family 1342 1430 2.8E-10 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS10015 9612c6c377d2a176c4a7e8d682eed3c8 1445 SUPERFAMILY SSF53850 996 1016 1.0E-57 T 29-03-2018 THSYN_RS10015 9612c6c377d2a176c4a7e8d682eed3c8 1445 SUPERFAMILY SSF53850 1060 1292 1.0E-57 T 29-03-2018 THSYN_RS10015 9612c6c377d2a176c4a7e8d682eed3c8 1445 Gene3D G3DSA:3.40.190.10 990 1130 6.7E-8 T 29-03-2018 THSYN_RS10015 9612c6c377d2a176c4a7e8d682eed3c8 1445 Gene3D G3DSA:3.30.1330.60 1280 1445 3.2E-19 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS10015 9612c6c377d2a176c4a7e8d682eed3c8 1445 Gene3D G3DSA:3.40.190.10 1131 1254 1.4E-31 T 29-03-2018 THSYN_RS10015 9612c6c377d2a176c4a7e8d682eed3c8 1445 Pfam PF12849 PBP superfamily domain 1063 1278 1.0E-26 T 29-03-2018 IPR024370 PBP domain THSYN_RS28270 9cb9ecd07cd46ff519a736f9c301ed09 99 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 8 73 4.4E-17 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS28270 9cb9ecd07cd46ff519a736f9c301ed09 99 Gene3D G3DSA:3.40.1620.10 9 66 9.0E-15 T 29-03-2018 THSYN_RS28270 9cb9ecd07cd46ff519a736f9c301ed09 99 SUPERFAMILY SSF143120 9 82 3.92E-16 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS28270 9cb9ecd07cd46ff519a736f9c301ed09 99 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 11 63 2.4E-12 T 29-03-2018 THSYN_RS24785 ddc3f214addf125e32ac5f2f4356d584 560 Pfam PF00691 OmpA family 457 552 1.8E-14 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS24785 ddc3f214addf125e32ac5f2f4356d584 560 PRINTS PR01021 OMPA domain signature 503 519 3.3E-5 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS24785 ddc3f214addf125e32ac5f2f4356d584 560 PRINTS PR01021 OMPA domain signature 488 503 3.3E-5 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS24785 ddc3f214addf125e32ac5f2f4356d584 560 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 541 560 1.6E-6 T 29-03-2018 THSYN_RS24785 ddc3f214addf125e32ac5f2f4356d584 560 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 503 520 1.6E-6 T 29-03-2018 THSYN_RS24785 ddc3f214addf125e32ac5f2f4356d584 560 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 521 540 1.6E-6 T 29-03-2018 THSYN_RS24785 ddc3f214addf125e32ac5f2f4356d584 560 Gene3D G3DSA:3.30.1330.60 188 560 2.6E-29 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS24785 ddc3f214addf125e32ac5f2f4356d584 560 Pfam PF06078 Bacterial protein of unknown function (DUF937) 34 114 6.1E-7 T 29-03-2018 IPR009282 Protein of unknown function DUF937 THSYN_RS24785 ddc3f214addf125e32ac5f2f4356d584 560 SUPERFAMILY SSF140804 35 122 7.98E-19 T 29-03-2018 IPR027405 YidB-like THSYN_RS24785 ddc3f214addf125e32ac5f2f4356d584 560 Gene3D G3DSA:1.10.10.690 1 136 1.3E-19 T 29-03-2018 THSYN_RS24785 ddc3f214addf125e32ac5f2f4356d584 560 SUPERFAMILY SSF103088 449 556 1.28E-28 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS22910 6a28323334dbe5c68d514cd21619ed62 285 Pfam PF04333 MlaA lipoprotein 37 229 2.6E-74 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 THSYN_RS22910 6a28323334dbe5c68d514cd21619ed62 285 PRINTS PR01805 VacJ lipoprotein signature 55 71 6.1E-24 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 THSYN_RS22910 6a28323334dbe5c68d514cd21619ed62 285 PRINTS PR01805 VacJ lipoprotein signature 106 123 6.1E-24 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 THSYN_RS22910 6a28323334dbe5c68d514cd21619ed62 285 PRINTS PR01805 VacJ lipoprotein signature 38 51 6.1E-24 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 THSYN_RS22910 6a28323334dbe5c68d514cd21619ed62 285 PRINTS PR01805 VacJ lipoprotein signature 142 159 6.1E-24 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 THSYN_RS05415 b6947d62243ec86899d8d226c1bb0d1c 172 SUPERFAMILY SSF88874 1 166 6.02E-49 T 29-03-2018 THSYN_RS05415 b6947d62243ec86899d8d226c1bb0d1c 172 Gene3D G3DSA:4.10.1070.10 55 152 2.3E-5 T 29-03-2018 THSYN_RS05415 b6947d62243ec86899d8d226c1bb0d1c 172 Pfam PF07484 Phage Tail Collar Domain 7 63 1.2E-28 T 29-03-2018 IPR011083 Phage tail collar domain THSYN_RS05415 b6947d62243ec86899d8d226c1bb0d1c 172 Gene3D G3DSA:3.90.1340.10 1 54 1.2E-22 T 29-03-2018 IPR011083 Phage tail collar domain THSYN_RS32145 bad9fa01d6449dff8d4a78aaa6375ab6 291 SUPERFAMILY SSF52540 4 234 4.69E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS32145 bad9fa01d6449dff8d4a78aaa6375ab6 291 Gene3D G3DSA:3.40.50.300 1 244 5.3E-60 T 29-03-2018 THSYN_RS32145 bad9fa01d6449dff8d4a78aaa6375ab6 291 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 15 204 9.2E-82 T 29-03-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 THSYN_RS32145 bad9fa01d6449dff8d4a78aaa6375ab6 291 Pfam PF00005 ABC transporter 22 170 6.8E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS32145 bad9fa01d6449dff8d4a78aaa6375ab6 291 SMART SM00382 31 218 8.8E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS32145 bad9fa01d6449dff8d4a78aaa6375ab6 291 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS01935 93c98baeebb74ecc5d8eb9eb378092e2 294 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 30 293 1.9E-88 T 29-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 THSYN_RS01935 93c98baeebb74ecc5d8eb9eb378092e2 294 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 129 292 8.5E-52 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 THSYN_RS01935 93c98baeebb74ecc5d8eb9eb378092e2 294 Gene3D G3DSA:3.20.20.70 154 283 2.9E-40 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS01935 93c98baeebb74ecc5d8eb9eb378092e2 294 SUPERFAMILY SSF51690 129 293 9.03E-57 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 THSYN_RS01935 93c98baeebb74ecc5d8eb9eb378092e2 294 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 39 126 2.7E-25 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 THSYN_RS01935 93c98baeebb74ecc5d8eb9eb378092e2 294 PIRSF PIRSF006250 21 294 8.2E-89 T 29-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 THSYN_RS01935 93c98baeebb74ecc5d8eb9eb378092e2 294 SUPERFAMILY SSF54675 24 127 1.06E-29 T 29-03-2018 THSYN_RS01935 93c98baeebb74ecc5d8eb9eb378092e2 294 Gene3D G3DSA:3.90.1170.20 13 153 6.8E-42 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 THSYN_RS15980 a5cfaa0438e703acda2a6fbe057d1f11 498 Gene3D G3DSA:3.90.350.10 166 417 0.0014 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS15980 a5cfaa0438e703acda2a6fbe057d1f11 498 Pfam PF05598 Transposase domain (DUF772) 59 119 2.2E-12 T 29-03-2018 IPR008490 Transposase InsH, N-terminal THSYN_RS15980 a5cfaa0438e703acda2a6fbe057d1f11 498 Pfam PF13751 Transposase DDE domain 352 474 4.1E-18 T 29-03-2018 IPR025668 Transposase DDE domain THSYN_RS33165 a5cfaa0438e703acda2a6fbe057d1f11 498 Gene3D G3DSA:3.90.350.10 166 417 0.0014 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS33165 a5cfaa0438e703acda2a6fbe057d1f11 498 Pfam PF05598 Transposase domain (DUF772) 59 119 2.2E-12 T 29-03-2018 IPR008490 Transposase InsH, N-terminal THSYN_RS33165 a5cfaa0438e703acda2a6fbe057d1f11 498 Pfam PF13751 Transposase DDE domain 352 474 4.1E-18 T 29-03-2018 IPR025668 Transposase DDE domain THSYN_RS09745 1045b3d3dee75c9414374edc15ad4c15 1237 Pfam PF04205 FMN-binding domain 875 953 2.2E-11 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 THSYN_RS09745 1045b3d3dee75c9414374edc15ad4c15 1237 Pfam PF01564 Spermine/spermidine synthase domain 309 427 4.2E-12 T 29-03-2018 THSYN_RS09745 1045b3d3dee75c9414374edc15ad4c15 1237 Pfam PF12801 4Fe-4S binding domain 1046 1083 2.4E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS09745 1045b3d3dee75c9414374edc15ad4c15 1237 Pfam PF12801 4Fe-4S binding domain 1135 1174 2.6E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS09745 1045b3d3dee75c9414374edc15ad4c15 1237 SMART SM00900 875 956 5.8E-13 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 THSYN_RS09745 1045b3d3dee75c9414374edc15ad4c15 1237 Gene3D G3DSA:3.40.50.150 291 505 2.0E-13 T 29-03-2018 THSYN_RS09745 1045b3d3dee75c9414374edc15ad4c15 1237 Gene3D G3DSA:3.30.70.20 1154 1207 0.055 T 29-03-2018 THSYN_RS09745 1045b3d3dee75c9414374edc15ad4c15 1237 SUPERFAMILY SSF53335 248 469 1.23E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS09745 1045b3d3dee75c9414374edc15ad4c15 1237 SUPERFAMILY SSF54862 1199 1206 9.91E-5 T 29-03-2018 THSYN_RS09745 1045b3d3dee75c9414374edc15ad4c15 1237 SUPERFAMILY SSF54862 1054 1072 9.91E-5 T 29-03-2018 THSYN_RS09745 1045b3d3dee75c9414374edc15ad4c15 1237 SUPERFAMILY SSF54862 1112 1165 9.91E-5 T 29-03-2018 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 SUPERFAMILY SSF81660 335 531 1.0E-45 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 PRINTS PR01021 OMPA domain signature 1111 1127 4.5E-6 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 PRINTS PR01021 OMPA domain signature 1066 1088 4.5E-6 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 PRINTS PR01021 OMPA domain signature 1096 1111 4.5E-6 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 626 642 1.6E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 598 614 1.6E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 658 683 1.6E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 483 501 1.6E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 Gene3D G3DSA:3.40.1110.10 292 526 4.1E-44 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 Gene3D G3DSA:3.30.1330.60 956 1171 8.2E-29 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 Pfam PF00691 OmpA family 1066 1158 5.6E-14 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 SUPERFAMILY SSF81653 119 228 1.31E-28 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 Pfam PF00122 E1-E2 ATPase 115 307 9.0E-52 T 29-03-2018 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 SUPERFAMILY SSF56784 326 346 2.57E-59 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 SUPERFAMILY SSF56784 480 730 2.57E-59 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 SUPERFAMILY SSF103088 1059 1166 9.03E-24 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 Gene3D G3DSA:1.20.1110.10 647 886 6.8E-71 T 29-03-2018 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 Pfam PF00702 haloacid dehalogenase-like hydrolase 326 640 4.5E-22 T 29-03-2018 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 Gene3D G3DSA:3.40.50.1000 527 646 1.8E-21 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 330 336 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 Pfam PF00689 Cation transporting ATPase, C-terminus 711 879 4.2E-50 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 597 716 7.5E-33 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 87 349 8.0E-45 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 328 342 1.8E-40 T 29-03-2018 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 626 645 1.8E-40 T 29-03-2018 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 527 538 1.8E-40 T 29-03-2018 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 549 559 1.8E-40 T 29-03-2018 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 166 180 1.8E-40 T 29-03-2018 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 650 662 1.8E-40 T 29-03-2018 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 Gene3D G3DSA:2.70.150.10 16 230 1.5E-44 T 29-03-2018 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 SMART SM00831 7 81 1.3E-24 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 SUPERFAMILY SSF81665 676 881 5.36E-132 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 SUPERFAMILY SSF81665 229 322 5.36E-132 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 SUPERFAMILY SSF81665 7 119 5.36E-132 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS26670 c74a1fadb59f3ad972578524e900d2de 1171 Pfam PF00690 Cation transporter/ATPase, N-terminus 8 76 1.5E-16 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THSYN_RS16710 eee182b8d266fa9b706251a4f62f8383 418 Gene3D G3DSA:3.90.1150.10 276 416 1.6E-54 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS16710 eee182b8d266fa9b706251a4f62f8383 418 SUPERFAMILY SSF53383 6 416 6.19E-180 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS16710 eee182b8d266fa9b706251a4f62f8383 418 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 51.99 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 THSYN_RS16710 eee182b8d266fa9b706251a4f62f8383 418 Gene3D G3DSA:3.40.640.10 37 275 1.8E-52 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS16710 eee182b8d266fa9b706251a4f62f8383 418 PIRSF PIRSF000412 1 417 3.3E-162 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 THSYN_RS16710 eee182b8d266fa9b706251a4f62f8383 418 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 THSYN_RS16710 eee182b8d266fa9b706251a4f62f8383 418 Pfam PF00464 Serine hydroxymethyltransferase 9 386 2.6E-175 T 29-03-2018 THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 SUPERFAMILY SSF55486 211 456 1.44E-77 T 29-03-2018 THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 564 883 2.7E-124 T 29-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 Gene3D G3DSA:2.60.40.1730 16 199 1.6E-30 T 29-03-2018 THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 SUPERFAMILY SSF63737 7 199 1.15E-43 T 29-03-2018 THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 132 147 3.8E-10 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 319 331 3.8E-10 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 264 274 3.8E-10 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 300 315 3.8E-10 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 182 197 3.8E-10 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 450 561 2.1E-27 T 29-03-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 Pfam PF01433 Peptidase family M1 domain 214 445 4.8E-55 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 882 0.0 T 29-03-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 Gene3D G3DSA:1.10.390.10 287 449 1.2E-49 T 29-03-2018 THSYN_RS20060 e42f1a48e66a1308abef95b42b2fa822 885 Gene3D G3DSA:1.25.50.10 562 882 9.5E-128 T 29-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal THSYN_RS17810 6d004720eb033f41eeadd69ab9ae7a3b 458 Gene3D G3DSA:1.10.3090.10 173 424 3.6E-40 T 29-03-2018 THSYN_RS17810 6d004720eb033f41eeadd69ab9ae7a3b 458 SUPERFAMILY SSF81891 175 412 1.7E-45 T 29-03-2018 THSYN_RS17810 6d004720eb033f41eeadd69ab9ae7a3b 458 Pfam PF12626 Polymerase A arginine-rich C-terminus 320 432 2.8E-41 T 29-03-2018 IPR025866 Polymerase A arginine-rich C-terminal domain THSYN_RS17810 6d004720eb033f41eeadd69ab9ae7a3b 458 SUPERFAMILY SSF81301 20 172 1.09E-38 T 29-03-2018 THSYN_RS17810 6d004720eb033f41eeadd69ab9ae7a3b 458 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 12 435 37.501 T 29-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 THSYN_RS17810 6d004720eb033f41eeadd69ab9ae7a3b 458 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 203 264 8.3E-18 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 THSYN_RS17810 6d004720eb033f41eeadd69ab9ae7a3b 458 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 17 434 9.5E-153 T 29-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 THSYN_RS17810 6d004720eb033f41eeadd69ab9ae7a3b 458 Pfam PF01743 Poly A polymerase head domain 49 176 7.9E-37 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 THSYN_RS17810 6d004720eb033f41eeadd69ab9ae7a3b 458 Gene3D G3DSA:3.30.460.10 15 172 7.3E-51 T 29-03-2018 THSYN_RS03895 c3fb4abc4071bdfad109426a5b4cf409 116 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 97 114 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 THSYN_RS03895 c3fb4abc4071bdfad109426a5b4cf409 116 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 116 34.703 T 29-03-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 THSYN_RS03895 c3fb4abc4071bdfad109426a5b4cf409 116 SUPERFAMILY SSF89360 7 102 2.16E-29 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS03895 c3fb4abc4071bdfad109426a5b4cf409 116 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 13 116 8.8E-37 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 THSYN_RS03895 c3fb4abc4071bdfad109426a5b4cf409 116 Pfam PF01521 Iron-sulphur cluster biosynthesis 11 111 2.3E-19 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS03895 c3fb4abc4071bdfad109426a5b4cf409 116 Gene3D G3DSA:2.60.300.12 11 116 2.2E-37 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS23010 ef9aaba8414d36b6152adefb7d60b4d9 364 SUPERFAMILY SSF53474 82 239 6.23E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS23010 ef9aaba8414d36b6152adefb7d60b4d9 364 SUPERFAMILY SSF53474 278 310 6.23E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS23010 ef9aaba8414d36b6152adefb7d60b4d9 364 Gene3D G3DSA:3.40.50.1820 78 346 8.4E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS19060 6e34f54d4e1b7aa9b7d1c82016b19e36 380 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 8 362 3.8E-102 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 THSYN_RS19060 6e34f54d4e1b7aa9b7d1c82016b19e36 380 PIRSF PIRSF000267 3 379 2.8E-119 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 THSYN_RS19060 6e34f54d4e1b7aa9b7d1c82016b19e36 380 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 380 6.3E-155 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 THSYN_RS20550 34d2235a99c0fc7dd2e7fe3ebe69ae2a 246 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 207 214 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS20550 34d2235a99c0fc7dd2e7fe3ebe69ae2a 246 PIRSF PIRSF000349 27 246 1.5E-75 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS20550 34d2235a99c0fc7dd2e7fe3ebe69ae2a 246 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 136 238 2.4E-36 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS20550 34d2235a99c0fc7dd2e7fe3ebe69ae2a 246 SUPERFAMILY SSF54719 132 244 3.4E-40 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS20550 34d2235a99c0fc7dd2e7fe3ebe69ae2a 246 Gene3D G3DSA:1.10.287.990 63 128 1.6E-24 T 29-03-2018 THSYN_RS20550 34d2235a99c0fc7dd2e7fe3ebe69ae2a 246 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 46 128 2.8E-26 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS20550 34d2235a99c0fc7dd2e7fe3ebe69ae2a 246 PRINTS PR01703 Manganese superoxide dismutase signature 111 124 1.7E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS20550 34d2235a99c0fc7dd2e7fe3ebe69ae2a 246 PRINTS PR01703 Manganese superoxide dismutase signature 165 173 1.7E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS20550 34d2235a99c0fc7dd2e7fe3ebe69ae2a 246 PRINTS PR01703 Manganese superoxide dismutase signature 205 217 1.7E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS20550 34d2235a99c0fc7dd2e7fe3ebe69ae2a 246 PRINTS PR01703 Manganese superoxide dismutase signature 70 83 1.7E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS20550 34d2235a99c0fc7dd2e7fe3ebe69ae2a 246 PRINTS PR01703 Manganese superoxide dismutase signature 49 60 1.7E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS20550 34d2235a99c0fc7dd2e7fe3ebe69ae2a 246 SUPERFAMILY SSF46609 42 129 1.31E-29 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS26835 a613e23ddbfdba3e857128905ae9ea5f 265 SUPERFAMILY SSF53335 34 258 9.72E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS26835 a613e23ddbfdba3e857128905ae9ea5f 265 Pfam PF04989 Cephalosporin hydroxylase 39 258 6.7E-95 T 29-03-2018 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 THSYN_RS26835 a613e23ddbfdba3e857128905ae9ea5f 265 Gene3D G3DSA:3.40.50.150 13 245 9.7E-8 T 29-03-2018 THSYN_RS20390 07de3c45ac85d7005a6456529c6cce39 560 SUPERFAMILY SSF52540 6 271 1.26E-122 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS20390 07de3c45ac85d7005a6456529c6cce39 560 Hamap MF_01227 CTP synthase [pyrG]. 6 543 51.451 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 THSYN_RS20390 07de3c45ac85d7005a6456529c6cce39 560 Gene3D G3DSA:3.40.50.300 1 288 9.6E-129 T 29-03-2018 THSYN_RS20390 07de3c45ac85d7005a6456529c6cce39 560 Pfam PF00117 Glutamine amidotransferase class-I 304 537 1.6E-56 T 29-03-2018 IPR017926 Glutamine amidotransferase THSYN_RS20390 07de3c45ac85d7005a6456529c6cce39 560 SUPERFAMILY SSF52317 292 543 3.73E-85 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS20390 07de3c45ac85d7005a6456529c6cce39 560 TIGRFAM TIGR00337 PyrG: CTP synthase 5 538 2.6E-247 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 THSYN_RS20390 07de3c45ac85d7005a6456529c6cce39 560 Pfam PF06418 CTP synthase N-terminus 7 269 2.2E-125 T 29-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 THSYN_RS20390 07de3c45ac85d7005a6456529c6cce39 560 Gene3D G3DSA:3.40.50.880 289 546 1.2E-72 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS26810 8fe9b4c2b24b49a48a9d3015dae57c79 356 SUPERFAMILY SSF51735 1 334 1.05E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS26810 8fe9b4c2b24b49a48a9d3015dae57c79 356 Gene3D G3DSA:3.40.50.720 2 195 3.2E-26 T 29-03-2018 THSYN_RS26810 8fe9b4c2b24b49a48a9d3015dae57c79 356 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 172 4.5E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS26810 8fe9b4c2b24b49a48a9d3015dae57c79 356 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 2 350 4.6E-143 T 29-03-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 THSYN_RS26810 8fe9b4c2b24b49a48a9d3015dae57c79 356 Gene3D G3DSA:3.90.25.10 196 354 7.2E-27 T 29-03-2018 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 SUPERFAMILY SSF82714 704 789 6.28E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 Gene3D G3DSA:3.30.70.1430 553 653 2.6E-10 T 29-03-2018 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 Gene3D G3DSA:3.30.70.1430 43 147 3.6E-29 T 29-03-2018 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 SUPERFAMILY SSF82866 787 1008 1.83E-44 T 29-03-2018 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 Gene3D G3DSA:1.20.1640.10 291 501 1.2E-26 T 29-03-2018 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 Pfam PF00873 AcrB/AcrD/AcrF family 8 1005 3.8E-155 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 Gene3D G3DSA:1.20.1640.10 807 1008 1.1E-33 T 29-03-2018 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 5.2E-19 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 PRINTS PR00702 Acriflavin resistance protein family signature 359 380 5.2E-19 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 5.2E-19 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 5.2E-19 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 PRINTS PR00702 Acriflavin resistance protein family signature 538 555 5.2E-19 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 5.2E-19 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 SUPERFAMILY SSF82693 140 185 1.65E-18 T 29-03-2018 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 SUPERFAMILY SSF82693 271 326 1.65E-18 T 29-03-2018 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 SUPERFAMILY SSF82866 295 489 8.5E-30 T 29-03-2018 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 SUPERFAMILY SSF82714 188 268 1.14E-8 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 Gene3D G3DSA:3.30.2090.10 703 790 1.1E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 SUPERFAMILY SSF82693 43 139 3.01E-17 T 29-03-2018 THSYN_RS18180 6affcc1ab737193bb58c96ff4d52ebc0 1034 Gene3D G3DSA:3.30.2090.10 184 270 2.9E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS20000 1aa9510a4c2c46550767ed2b7eacfa5f 100 Pfam PF03692 Putative zinc- or iron-chelating domain 17 85 1.6E-7 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein THSYN_RS32125 f7aeb121902328cb9990cd22ae53cb87 219 PRINTS PR01021 OMPA domain signature 157 173 5.9E-8 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS32125 f7aeb121902328cb9990cd22ae53cb87 219 PRINTS PR01021 OMPA domain signature 112 134 5.9E-8 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS32125 f7aeb121902328cb9990cd22ae53cb87 219 PRINTS PR01021 OMPA domain signature 142 157 5.9E-8 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS32125 f7aeb121902328cb9990cd22ae53cb87 219 Gene3D G3DSA:3.30.1330.60 67 215 1.3E-31 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS32125 f7aeb121902328cb9990cd22ae53cb87 219 SUPERFAMILY SSF103088 98 212 9.16E-32 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS32125 f7aeb121902328cb9990cd22ae53cb87 219 Pfam PF00691 OmpA family 112 206 7.7E-20 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS32125 f7aeb121902328cb9990cd22ae53cb87 219 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 157 174 9.6E-7 T 29-03-2018 THSYN_RS32125 f7aeb121902328cb9990cd22ae53cb87 219 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 175 194 9.6E-7 T 29-03-2018 THSYN_RS32125 f7aeb121902328cb9990cd22ae53cb87 219 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 195 215 9.6E-7 T 29-03-2018 THSYN_RS05105 399f426ad0cf82f2467817e39ea4a868 323 Gene3D G3DSA:3.90.1570.10 42 226 4.5E-20 T 29-03-2018 THSYN_RS05105 399f426ad0cf82f2467817e39ea4a868 323 Pfam PF05685 Putative restriction endonuclease 53 219 6.4E-14 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS05105 399f426ad0cf82f2467817e39ea4a868 323 SUPERFAMILY SSF52980 42 223 1.93E-16 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS09940 a04bc8e36d4dd48228dd73a70c3a5aff 382 Gene3D G3DSA:3.40.50.410 102 347 0.001 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS07480 f5ca0449083dbe1862d8d272f3a5e87f 472 SMART SM00670 10 152 2.4E-6 T 29-03-2018 IPR002716 PIN domain THSYN_RS07480 f5ca0449083dbe1862d8d272f3a5e87f 472 Pfam PF02562 PhoH-like protein 261 458 3.1E-54 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 THSYN_RS07480 f5ca0449083dbe1862d8d272f3a5e87f 472 Pfam PF13638 PIN domain 12 164 2.0E-38 T 29-03-2018 IPR002716 PIN domain THSYN_RS07480 f5ca0449083dbe1862d8d272f3a5e87f 472 SUPERFAMILY SSF88723 9 71 8.04E-15 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS07480 f5ca0449083dbe1862d8d272f3a5e87f 472 SUPERFAMILY SSF88723 115 166 8.04E-15 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS07480 f5ca0449083dbe1862d8d272f3a5e87f 472 Gene3D G3DSA:3.40.50.1010 9 202 6.3E-42 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS07480 f5ca0449083dbe1862d8d272f3a5e87f 472 Gene3D G3DSA:3.40.50.300 259 468 8.1E-18 T 29-03-2018 THSYN_RS07480 f5ca0449083dbe1862d8d272f3a5e87f 472 SUPERFAMILY SSF52540 377 451 4.36E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07480 f5ca0449083dbe1862d8d272f3a5e87f 472 SUPERFAMILY SSF52540 260 346 4.36E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07480 f5ca0449083dbe1862d8d272f3a5e87f 472 SUPERFAMILY SSF52540 140 196 4.36E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12530 e28b3ff8321f1c118c4179fb75687715 489 Pfam PF00012 Hsp70 protein 105 323 1.6E-14 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS12530 e28b3ff8321f1c118c4179fb75687715 489 SUPERFAMILY SSF53067 1 122 5.61E-6 T 29-03-2018 THSYN_RS12530 e28b3ff8321f1c118c4179fb75687715 489 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 130 143 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THSYN_RS12530 e28b3ff8321f1c118c4179fb75687715 489 SUPERFAMILY SSF53067 125 325 4.65E-24 T 29-03-2018 THSYN_RS12530 e28b3ff8321f1c118c4179fb75687715 489 Gene3D G3DSA:3.30.420.40 135 308 1.9E-18 T 29-03-2018 THSYN_RS12530 e28b3ff8321f1c118c4179fb75687715 489 Gene3D G3DSA:2.60.34.10 332 480 1.1E-4 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 THSYN_RS12530 e28b3ff8321f1c118c4179fb75687715 489 Gene3D G3DSA:3.30.420.40 1 134 2.1E-14 T 29-03-2018 THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 SUPERFAMILY SSF82697 1 152 6.8E-42 T 29-03-2018 THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 SUPERFAMILY SSF109736 156 220 5.36E-19 T 29-03-2018 THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 Pfam PF02769 AIR synthase related protein, C-terminal domain 434 590 3.4E-27 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 Pfam PF02769 AIR synthase related protein, C-terminal domain 840 973 5.7E-15 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1046 1299 5.7E-101 T 29-03-2018 THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 SUPERFAMILY SSF55326 624 818 3.14E-62 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 SUPERFAMILY SSF56042 827 1021 7.03E-48 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 Gene3D G3DSA:3.30.1330.10 645 815 7.3E-19 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1300 20.833 T 29-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 3 1299 0.0 T 29-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 SUPERFAMILY SSF52317 1044 1299 2.75E-94 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 Gene3D G3DSA:3.40.50.880 1045 1299 3.6E-32 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 SUPERFAMILY SSF56042 433 656 1.24E-50 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 Gene3D G3DSA:3.90.650.10 823 1001 5.2E-29 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 Gene3D G3DSA:3.30.1330.10 184 218 0.003 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 Gene3D G3DSA:3.30.1330.10 219 414 6.2E-48 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 SMART SM01211 1046 1299 5.8E-148 T 29-03-2018 THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 Gene3D G3DSA:3.90.650.10 415 608 2.1E-33 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS28385 335799dfe0dee5ba58a7d8384c5c8b31 1300 SUPERFAMILY SSF55326 222 429 2.55E-59 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS11620 68ded76615f26e3e1aaf80143ee80c45 397 Pfam PF00155 Aminotransferase class I and II 40 378 1.8E-59 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THSYN_RS11620 68ded76615f26e3e1aaf80143ee80c45 397 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 2 382 51.192 T 29-03-2018 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 THSYN_RS11620 68ded76615f26e3e1aaf80143ee80c45 397 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 233 242 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 THSYN_RS11620 68ded76615f26e3e1aaf80143ee80c45 397 Gene3D G3DSA:3.90.1150.10 280 381 2.8E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS11620 68ded76615f26e3e1aaf80143ee80c45 397 Gene3D G3DSA:3.40.640.10 77 279 1.1E-50 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS11620 68ded76615f26e3e1aaf80143ee80c45 397 SUPERFAMILY SSF53383 6 379 8.51E-109 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS11620 68ded76615f26e3e1aaf80143ee80c45 397 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 18 378 1.4E-146 T 29-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 THSYN_RS20505 0e4d2aed3fac1e5ac0282f25f306f083 363 Gene3D G3DSA:3.30.450.90 1 45 5.9E-4 T 29-03-2018 THSYN_RS20505 0e4d2aed3fac1e5ac0282f25f306f083 363 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 92 323 2.1E-97 T 29-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 THSYN_RS20505 0e4d2aed3fac1e5ac0282f25f306f083 363 SUPERFAMILY SSF52540 88 316 1.77E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS20505 0e4d2aed3fac1e5ac0282f25f306f083 363 SUPERFAMILY SSF52540 18 58 1.77E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS20505 0e4d2aed3fac1e5ac0282f25f306f083 363 Gene3D G3DSA:3.40.50.300 252 326 7.6E-14 T 29-03-2018 THSYN_RS20505 0e4d2aed3fac1e5ac0282f25f306f083 363 Gene3D G3DSA:3.40.50.300 87 251 5.7E-25 T 29-03-2018 THSYN_RS20505 0e4d2aed3fac1e5ac0282f25f306f083 363 SMART SM00382 101 226 0.0016 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS20505 0e4d2aed3fac1e5ac0282f25f306f083 363 Pfam PF00437 Type II/IV secretion system protein 39 249 5.4E-35 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THSYN_RS01415 4b57b10c012a085e68d37d3ce6bab785 198 Gene3D G3DSA:3.40.50.300 3 190 4.8E-5 T 29-03-2018 THSYN_RS23915 45ac88123d18b9211b7972946ebb849b 217 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 210 37.809 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23915 45ac88123d18b9211b7972946ebb849b 217 SUPERFAMILY SSF50447 1 214 2.21E-75 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS23915 45ac88123d18b9211b7972946ebb849b 217 ProSitePatterns PS00474 Ribosomal protein L3 signature. 104 127 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site THSYN_RS23915 45ac88123d18b9211b7972946ebb849b 217 Pfam PF00297 Ribosomal protein L3 102 185 1.8E-16 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23915 45ac88123d18b9211b7972946ebb849b 217 Gene3D G3DSA:4.10.960.10 47 168 4.8E-31 T 29-03-2018 THSYN_RS23915 45ac88123d18b9211b7972946ebb849b 217 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 206 6.3E-82 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Gene3D G3DSA:3.40.50.2300 772 913 6.3E-41 T 29-03-2018 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 SUPERFAMILY SSF52172 634 758 5.55E-30 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 SUPERFAMILY SSF47384 372 453 9.22E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 SUPERFAMILY SSF47226 928 1037 9.29E-15 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Pfam PF00512 His Kinase A (phospho-acceptor) domain 388 452 3.7E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Gene3D G3DSA:3.30.565.10 456 622 1.5E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Pfam PF00072 Response regulator receiver domain 637 753 9.4E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Pfam PF00072 Response regulator receiver domain 9 98 8.8E-13 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Pfam PF00072 Response regulator receiver domain 781 895 6.8E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Pfam PF00072 Response regulator receiver domain 156 255 3.2E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 SUPERFAMILY SSF55874 442 611 2.36E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 499 614 1.3E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 SUPERFAMILY SSF52172 155 303 1.07E-25 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 SMART SM00448 7 117 1.5E-8 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 SMART SM00448 779 895 3.6E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 SMART SM00448 154 265 5.0E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 SMART SM00448 635 753 1.4E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 PRINTS PR00344 Bacterial sensor protein C-terminal signature 558 568 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 PRINTS PR00344 Bacterial sensor protein C-terminal signature 540 554 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 PRINTS PR00344 Bacterial sensor protein C-terminal signature 599 612 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 PRINTS PR00344 Bacterial sensor protein C-terminal signature 575 593 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 SUPERFAMILY SSF52172 2 128 1.12E-18 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Gene3D G3DSA:3.40.50.2300 3 148 1.6E-19 T 29-03-2018 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 SMART SM00387 499 615 1.0E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Gene3D G3DSA:3.40.50.2300 149 377 2.4E-23 T 29-03-2018 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 SMART SM00388 387 452 2.9E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Pfam PF01627 Hpt domain 953 1031 1.1E-8 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Gene3D G3DSA:1.10.287.130 378 448 1.9E-16 T 29-03-2018 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Gene3D G3DSA:3.40.50.2300 632 771 3.4E-30 T 29-03-2018 THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 SUPERFAMILY SSF52172 777 906 2.99E-37 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS18620 fd599fcc1be27973653015f5803bf22e 1047 Gene3D G3DSA:1.20.120.160 923 1042 7.6E-13 T 29-03-2018 THSYN_RS03535 14ebaea7535bb10f0e1498f021fcbfa7 452 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 27 446 6.9E-129 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03535 14ebaea7535bb10f0e1498f021fcbfa7 452 SUPERFAMILY SSF53244 315 446 2.13E-33 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THSYN_RS03535 14ebaea7535bb10f0e1498f021fcbfa7 452 Gene3D G3DSA:3.40.1390.10 3 87 8.3E-26 T 29-03-2018 THSYN_RS03535 14ebaea7535bb10f0e1498f021fcbfa7 452 Gene3D G3DSA:3.90.190.20 315 452 1.1E-41 T 29-03-2018 THSYN_RS03535 14ebaea7535bb10f0e1498f021fcbfa7 452 Pfam PF01225 Mur ligase family, catalytic domain 23 69 2.4E-9 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 THSYN_RS03535 14ebaea7535bb10f0e1498f021fcbfa7 452 Pfam PF02875 Mur ligase family, glutamate ligase domain 315 397 2.3E-10 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THSYN_RS03535 14ebaea7535bb10f0e1498f021fcbfa7 452 SUPERFAMILY SSF63418 2 95 1.44E-25 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 THSYN_RS03535 14ebaea7535bb10f0e1498f021fcbfa7 452 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 2 447 32.891 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03535 14ebaea7535bb10f0e1498f021fcbfa7 452 SUPERFAMILY SSF53623 99 311 2.09E-51 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS03535 14ebaea7535bb10f0e1498f021fcbfa7 452 Pfam PF08245 Mur ligase middle domain 103 295 3.4E-42 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS03535 14ebaea7535bb10f0e1498f021fcbfa7 452 Gene3D G3DSA:3.40.1190.10 88 311 4.6E-54 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS24055 8fd78d34913dff79b986811cab3a8cc0 300 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 12 32 5.2E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS24055 8fd78d34913dff79b986811cab3a8cc0 300 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 61 76 5.2E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS24055 8fd78d34913dff79b986811cab3a8cc0 300 Gene3D G3DSA:3.30.300.20 197 300 1.5E-36 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta THSYN_RS24055 8fd78d34913dff79b986811cab3a8cc0 300 Hamap MF_00367 GTPase Era [era]. 7 297 34.138 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24055 8fd78d34913dff79b986811cab3a8cc0 300 Gene3D G3DSA:1.20.120.430 3 63 1.6E-16 T 29-03-2018 THSYN_RS24055 8fd78d34913dff79b986811cab3a8cc0 300 TIGRFAM TIGR00436 era: GTP-binding protein Era 11 280 2.2E-82 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24055 8fd78d34913dff79b986811cab3a8cc0 300 SUPERFAMILY SSF54814 183 298 7.19E-37 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 THSYN_RS24055 8fd78d34913dff79b986811cab3a8cc0 300 Gene3D G3DSA:3.40.50.300 64 196 2.4E-14 T 29-03-2018 THSYN_RS24055 8fd78d34913dff79b986811cab3a8cc0 300 Pfam PF01926 50S ribosome-binding GTPase 12 126 5.6E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS24055 8fd78d34913dff79b986811cab3a8cc0 300 SUPERFAMILY SSF52540 12 205 1.4E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24055 8fd78d34913dff79b986811cab3a8cc0 300 Pfam PF07650 KH domain 210 285 5.1E-17 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS24055 8fd78d34913dff79b986811cab3a8cc0 300 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 166 1.8E-24 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS13000 86e00249230583c1b725d564eba2a97d 532 Gene3D G3DSA:2.60.40.10 428 532 7.9E-32 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS13000 86e00249230583c1b725d564eba2a97d 532 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 47 529 9.0E-190 T 29-03-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 THSYN_RS13000 86e00249230583c1b725d564eba2a97d 532 SUPERFAMILY SSF81296 429 529 2.24E-26 T 29-03-2018 IPR014756 Immunoglobulin E-set THSYN_RS13000 86e00249230583c1b725d564eba2a97d 532 Gene3D G3DSA:2.70.98.10 47 423 1.1E-153 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 THSYN_RS13000 86e00249230583c1b725d564eba2a97d 532 PIRSF PIRSF006281 14 532 3.9E-185 T 29-03-2018 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D THSYN_RS13000 86e00249230583c1b725d564eba2a97d 532 SUPERFAMILY SSF74650 47 423 3.08E-146 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 THSYN_RS05925 4d03af4ec722fe0006f83f4d7125036a 1035 Gene3D G3DSA:2.30.30.60 870 919 2.7E-13 T 29-03-2018 THSYN_RS05925 4d03af4ec722fe0006f83f4d7125036a 1035 SUPERFAMILY SSF50182 854 920 7.52E-17 T 29-03-2018 IPR010920 LSM domain THSYN_RS05925 4d03af4ec722fe0006f83f4d7125036a 1035 SUPERFAMILY SSF82861 771 853 4.18E-10 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 THSYN_RS05925 4d03af4ec722fe0006f83f4d7125036a 1035 Pfam PF00924 Mechanosensitive ion channel 812 1013 1.4E-47 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THSYN_RS05925 4d03af4ec722fe0006f83f4d7125036a 1035 SUPERFAMILY SSF82689 923 1024 2.88E-24 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 THSYN_RS05925 4d03af4ec722fe0006f83f4d7125036a 1035 Gene3D G3DSA:3.30.70.100 922 1018 1.6E-16 T 29-03-2018 THSYN_RS12680 f79642ebfef7e677b276a14a7391e5a7 156 Pfam PF08808 RES domain 5 149 9.3E-26 T 29-03-2018 IPR014914 RES domain THSYN_RS12680 f79642ebfef7e677b276a14a7391e5a7 156 SMART SM00953 15 142 1.1E-20 T 29-03-2018 IPR014914 RES domain THSYN_RS04115 d617ca01a3039367e8ed68b7f469d8d3 414 Pfam PF12704 MacB-like periplasmic core domain 19 254 3.5E-16 T 29-03-2018 IPR025857 MacB-like periplasmic core domain THSYN_RS04115 d617ca01a3039367e8ed68b7f469d8d3 414 Pfam PF02687 FtsX-like permease family 309 405 2.1E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 Gene3D G3DSA:2.40.50.180 651 720 3.3E-9 T 29-03-2018 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 Gene3D G3DSA:2.30.30.40 721 768 1.1E-12 T 29-03-2018 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 Gene3D G3DSA:1.20.120.160 142 270 8.3E-17 T 29-03-2018 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 Gene3D G3DSA:1.20.120.160 1 139 3.0E-24 T 29-03-2018 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 SMART SM00448 799 913 4.0E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 Pfam PF01627 Hpt domain 149 223 8.0E-9 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 Pfam PF01627 Hpt domain 3 95 1.2E-10 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 PRINTS PR00344 Bacterial sensor protein C-terminal signature 533 547 3.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 PRINTS PR00344 Bacterial sensor protein C-terminal signature 591 609 3.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 PRINTS PR00344 Bacterial sensor protein C-terminal signature 615 628 3.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 SUPERFAMILY SSF52172 800 919 9.53E-32 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 491 630 3.3E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 SUPERFAMILY SSF55874 446 629 2.62E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 Gene3D G3DSA:3.30.565.10 346 630 1.6E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 SMART SM00073 147 244 0.12 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 SMART SM00073 1 98 3.8E-10 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 Pfam PF00072 Response regulator receiver domain 801 910 5.9E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 Gene3D G3DSA:3.40.50.2300 793 930 8.9E-34 T 29-03-2018 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 SUPERFAMILY SSF47226 149 265 5.1E-14 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 SUPERFAMILY SSF47226 2 117 7.98E-23 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 SUPERFAMILY SSF50341 647 768 3.4E-23 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 SMART SM00260 623 768 1.2E-16 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 Pfam PF01584 CheW-like domain 648 771 8.9E-20 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS18605 7f504006147fc4c6d911a24a5ffaf85a 933 SMART SM00387 488 631 9.3E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS23875 72234906fef89912d412f011ef086ba5 66 Pfam PF00831 Ribosomal L29 protein 4 59 6.5E-22 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23875 72234906fef89912d412f011ef086ba5 66 Gene3D G3DSA:1.10.287.310 1 65 8.0E-24 T 29-03-2018 THSYN_RS23875 72234906fef89912d412f011ef086ba5 66 SUPERFAMILY SSF46561 1 62 9.94E-20 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23875 72234906fef89912d412f011ef086ba5 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 59 1.5E-19 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23875 72234906fef89912d412f011ef086ba5 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 16.778 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 SUPERFAMILY SSF55681 467 686 1.99E-46 T 29-03-2018 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 SMART SM00896 698 791 4.8E-40 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 Pfam PF01588 Putative tRNA binding domain 45 145 5.1E-26 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 Gene3D G3DSA:3.30.70.380 694 791 3.1E-24 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 SMART SM00873 212 385 9.1E-87 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 791 2.1E-237 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 SUPERFAMILY SSF56037 195 393 3.14E-70 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 SUPERFAMILY SSF46955 405 475 2.38E-16 T 29-03-2018 IPR009061 Putative DNA-binding domain THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 SUPERFAMILY SSF54991 693 791 4.18E-28 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 SMART SM00874 403 471 1.7E-24 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 Gene3D G3DSA:3.30.56.10 402 475 4.6E-21 T 29-03-2018 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 Gene3D G3DSA:3.50.40.10 197 394 2.3E-67 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 Gene3D G3DSA:3.30.930.10 495 687 3.4E-35 T 29-03-2018 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 785 42.866 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 Pfam PF03483 B3/4 domain 213 384 1.8E-65 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 Pfam PF03484 tRNA synthetase B5 domain 407 471 1.2E-15 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 Gene3D G3DSA:3.30.56.10 1 189 3.3E-47 T 29-03-2018 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 Pfam PF03147 Ferredoxin-fold anticodon binding domain 698 791 4.7E-27 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 THSYN_RS23995 659bf5ccb2639f09e4a0c2bde4057a02 792 SUPERFAMILY SSF50249 37 190 1.08E-47 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 SUPERFAMILY SSF55874 311 487 1.7E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 Gene3D G3DSA:3.40.50.2300 489 628 7.5E-23 T 29-03-2018 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 Gene3D G3DSA:3.40.50.2300 631 765 2.1E-43 T 29-03-2018 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 SUPERFAMILY SSF47384 242 323 1.06E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 463 1.5E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 482 1.5E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 424 1.5E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 438 1.5E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 SUPERFAMILY SSF52172 498 620 3.42E-22 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 SMART SM00448 641 757 4.3E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 SMART SM00448 501 616 2.3E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 SMART SM00388 257 322 2.2E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 Gene3D G3DSA:3.30.565.10 326 488 3.3E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 Gene3D G3DSA:3.30.450.20 86 260 2.7E-5 T 29-03-2018 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 Gene3D G3DSA:1.10.287.130 261 318 7.6E-18 T 29-03-2018 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 SUPERFAMILY SSF52172 642 762 2.13E-39 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 Pfam PF00072 Response regulator receiver domain 504 615 8.4E-11 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 Pfam PF00072 Response regulator receiver domain 643 757 4.2E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 SMART SM00387 369 485 4.8E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 Pfam PF00512 His Kinase A (phospho-acceptor) domain 257 322 3.7E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS00650 c240e01652e4ada29c792af2c5e8ddf3 765 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 369 483 7.2E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS15130 f8ff86b794822782620aefaf24042724 139 Gene3D G3DSA:1.20.120.330 9 137 1.5E-25 T 29-03-2018 THSYN_RS15130 f8ff86b794822782620aefaf24042724 139 SMART SM00748 21 129 7.6E-10 T 29-03-2018 IPR007842 HEPN domain THSYN_RS15130 f8ff86b794822782620aefaf24042724 139 Pfam PF05168 HEPN domain 19 132 1.5E-24 T 29-03-2018 IPR007842 HEPN domain THSYN_RS15130 f8ff86b794822782620aefaf24042724 139 SUPERFAMILY SSF81593 20 132 7.46E-21 T 29-03-2018 THSYN_RS07035 b9c67eb63a5c891d53d2f6af5d490155 472 Pfam PF00691 OmpA family 369 463 1.6E-21 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS07035 b9c67eb63a5c891d53d2f6af5d490155 472 Gene3D G3DSA:3.30.1330.60 26 472 2.7E-39 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS07035 b9c67eb63a5c891d53d2f6af5d490155 472 Pfam PF06078 Bacterial protein of unknown function (DUF937) 9 142 5.1E-16 T 29-03-2018 IPR009282 Protein of unknown function DUF937 THSYN_RS07035 b9c67eb63a5c891d53d2f6af5d490155 472 SUPERFAMILY SSF103088 363 469 3.4E-34 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS07035 b9c67eb63a5c891d53d2f6af5d490155 472 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 452 472 2.6E-5 T 29-03-2018 THSYN_RS07035 b9c67eb63a5c891d53d2f6af5d490155 472 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 414 431 2.6E-5 T 29-03-2018 THSYN_RS07035 b9c67eb63a5c891d53d2f6af5d490155 472 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 432 451 2.6E-5 T 29-03-2018 THSYN_RS07035 b9c67eb63a5c891d53d2f6af5d490155 472 PRINTS PR01021 OMPA domain signature 414 430 2.1E-11 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS07035 b9c67eb63a5c891d53d2f6af5d490155 472 PRINTS PR01021 OMPA domain signature 369 391 2.1E-11 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS07035 b9c67eb63a5c891d53d2f6af5d490155 472 PRINTS PR01021 OMPA domain signature 399 414 2.1E-11 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS22680 a599ff76bce8467c431d1dd08c41baa6 102 Gene3D G3DSA:3.40.1260.10 3 98 2.5E-23 T 29-03-2018 THSYN_RS22680 a599ff76bce8467c431d1dd08c41baa6 102 TIGRFAM TIGR03011 sulf_tusB_dsrH: sulfur relay protein TusB/DsrH 4 101 1.0E-29 T 29-03-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 THSYN_RS22680 a599ff76bce8467c431d1dd08c41baa6 102 Pfam PF04077 DsrH like protein 9 97 3.8E-27 T 29-03-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 THSYN_RS22680 a599ff76bce8467c431d1dd08c41baa6 102 SUPERFAMILY SSF75169 3 101 4.19E-28 T 29-03-2018 IPR027396 DsrEFH-like THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 SUPERFAMILY SSF52172 590 711 2.99E-36 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 Gene3D G3DSA:3.30.450.40 27 213 3.5E-4 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 Gene3D G3DSA:3.30.565.10 416 580 6.7E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 SMART SM00387 459 575 1.6E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 SMART SM00448 590 706 8.2E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 SUPERFAMILY SSF55785 224 337 2.27E-23 T 29-03-2018 IPR000014 PAS domain THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 SUPERFAMILY SSF55874 401 576 4.98E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 Pfam PF00072 Response regulator receiver domain 593 705 2.0E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 SUPERFAMILY SSF47384 333 413 9.02E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 SMART SM00388 347 412 3.9E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 Pfam PF08447 PAS fold 240 328 7.4E-21 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 459 574 3.5E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 215 340 1.3E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 SMART SM00086 292 334 2.7E-8 T 29-03-2018 IPR001610 PAC motif THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 Gene3D G3DSA:3.40.50.2300 581 712 8.7E-40 T 29-03-2018 THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 Pfam PF00512 His Kinase A (phospho-acceptor) domain 347 412 1.7E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 SMART SM00091 217 285 9.7E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 514 1.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 PRINTS PR00344 Bacterial sensor protein C-terminal signature 559 572 1.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 528 1.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 PRINTS PR00344 Bacterial sensor protein C-terminal signature 535 553 1.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 Gene3D G3DSA:3.30.450.20 214 342 1.5E-24 T 29-03-2018 THSYN_RS01185 890fcc95d090032baa70755eb0d5b9b0 712 Gene3D G3DSA:1.10.287.130 343 407 1.2E-17 T 29-03-2018 THSYN_RS03955 40e3111bed8b55f1ea4be0017392a850 418 Gene3D G3DSA:3.40.718.10 10 418 4.6E-129 T 29-03-2018 THSYN_RS03955 40e3111bed8b55f1ea4be0017392a850 418 SMART SM01329 30 414 6.5E-173 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THSYN_RS03955 40e3111bed8b55f1ea4be0017392a850 418 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 305 324 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 THSYN_RS03955 40e3111bed8b55f1ea4be0017392a850 418 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 418 1.8E-216 T 29-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 THSYN_RS03955 40e3111bed8b55f1ea4be0017392a850 418 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 31 413 2.2E-111 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THSYN_RS03955 40e3111bed8b55f1ea4be0017392a850 418 SUPERFAMILY SSF53659 4 418 1.52E-141 T 29-03-2018 THSYN_RS06325 7c8b540fbbdbcbad813ab179378d3c33 679 SUPERFAMILY SSF55718 533 654 2.06E-28 T 29-03-2018 IPR003033 SCP2 sterol-binding domain THSYN_RS06325 7c8b540fbbdbcbad813ab179378d3c33 679 SMART SM00849 125 348 1.0E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS06325 7c8b540fbbdbcbad813ab179378d3c33 679 Pfam PF00753 Metallo-beta-lactamase superfamily 121 348 8.4E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS06325 7c8b540fbbdbcbad813ab179378d3c33 679 Gene3D G3DSA:3.60.15.10 98 396 2.1E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS06325 7c8b540fbbdbcbad813ab179378d3c33 679 SUPERFAMILY SSF56281 25 525 3.93E-144 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS06325 7c8b540fbbdbcbad813ab179378d3c33 679 Pfam PF14863 Alkyl sulfatase dimerisation 385 523 3.7E-47 T 29-03-2018 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 THSYN_RS06325 7c8b540fbbdbcbad813ab179378d3c33 679 Pfam PF14864 Alkyl sulfatase C-terminal 531 653 1.4E-33 T 29-03-2018 IPR029229 Alkyl sulfatase, C-terminal THSYN_RS06325 7c8b540fbbdbcbad813ab179378d3c33 679 Gene3D G3DSA:3.30.1050.10 527 662 1.5E-19 T 29-03-2018 IPR003033 SCP2 sterol-binding domain THSYN_RS09645 f875040fdb807685f560662fb7252843 134 Pfam PF01850 PIN domain 4 116 2.5E-18 T 29-03-2018 IPR002716 PIN domain THSYN_RS09645 f875040fdb807685f560662fb7252843 134 SUPERFAMILY SSF88723 1 113 3.92E-22 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS09645 f875040fdb807685f560662fb7252843 134 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 120 10.158 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS09645 f875040fdb807685f560662fb7252843 134 Gene3D G3DSA:3.40.50.1010 1 122 1.9E-22 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS28190 2f1bbd0e13353ae06aa54b32699335ae 1079 Pfam PF14579 Helix-hairpin-helix motif 803 901 2.4E-22 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS28190 2f1bbd0e13353ae06aa54b32699335ae 1079 Gene3D G3DSA:3.20.20.140 37 266 6.3E-31 T 29-03-2018 THSYN_RS28190 2f1bbd0e13353ae06aa54b32699335ae 1079 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 39 878 2.0E-155 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS28190 2f1bbd0e13353ae06aa54b32699335ae 1079 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 307 729 4.4E-147 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS28190 2f1bbd0e13353ae06aa54b32699335ae 1079 Gene3D G3DSA:2.40.50.140 973 1067 4.7E-8 T 29-03-2018 THSYN_RS28190 2f1bbd0e13353ae06aa54b32699335ae 1079 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 38 1079 13.811 T 29-03-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS28190 2f1bbd0e13353ae06aa54b32699335ae 1079 SMART SM00481 39 106 6.1E-14 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal THSYN_RS28190 2f1bbd0e13353ae06aa54b32699335ae 1079 Pfam PF02811 PHP domain 41 142 5.0E-13 T 29-03-2018 IPR004013 PHP domain GO:0003824 THSYN_RS28190 2f1bbd0e13353ae06aa54b32699335ae 1079 SUPERFAMILY SSF89550 45 126 2.94E-9 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 THSYN_RS17580 9082cfc2fb650923e53a3b478845590f 85 Pfam PF13657 HipA N-terminal domain 4 38 5.0E-5 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 THSYN_RS08765 a0b475a1a653ef1acc56fb4be26e431b 553 Gene3D G3DSA:3.90.350.10 176 442 2.1E-4 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS08765 a0b475a1a653ef1acc56fb4be26e431b 553 Pfam PF13808 DDE_Tnp_1-associated 90 176 2.9E-15 T 29-03-2018 IPR032806 H repeat-associated protein, N-terminal THSYN_RS14125 148997e03f306bbb93d22b74a7c7d2b0 104 SUPERFAMILY SSF56436 74 90 1.95E-8 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS14125 148997e03f306bbb93d22b74a7c7d2b0 104 SUPERFAMILY SSF56436 1 33 1.95E-8 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS14125 148997e03f306bbb93d22b74a7c7d2b0 104 Pfam PF03781 Sulfatase-modifying factor enzyme 1 1 57 6.3E-8 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS14125 148997e03f306bbb93d22b74a7c7d2b0 104 Gene3D G3DSA:3.90.1580.10 1 87 1.1E-8 T 29-03-2018 THSYN_RS20300 bf457126dca1d21d09dd21093ca650df 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 THSYN_RS20300 bf457126dca1d21d09dd21093ca650df 107 SUPERFAMILY SSF89360 1 95 7.85E-27 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS20300 bf457126dca1d21d09dd21093ca650df 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 106 4.6E-36 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 THSYN_RS20300 bf457126dca1d21d09dd21093ca650df 107 Gene3D G3DSA:2.60.300.12 1 107 4.7E-35 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS20300 bf457126dca1d21d09dd21093ca650df 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 103 5.5E-19 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS13175 3f13eeaacc5b95ee0f1047382f15a0c5 90 SUPERFAMILY SSF47598 6 81 6.78E-20 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS13175 3f13eeaacc5b95ee0f1047382f15a0c5 90 Pfam PF08681 Protein of unknown function (DUF1778) 7 84 1.1E-23 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 THSYN_RS13175 3f13eeaacc5b95ee0f1047382f15a0c5 90 Gene3D G3DSA:1.20.890.30 51 86 1.6E-12 T 29-03-2018 THSYN_RS13175 3f13eeaacc5b95ee0f1047382f15a0c5 90 Gene3D G3DSA:1.10.1220.10 5 47 1.9E-10 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS10095 6d500580f70a6ce3b3d4bd5a3e0a2912 55 Gene3D G3DSA:3.30.50.10 13 54 1.6E-9 T 29-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 THSYN_RS10095 6d500580f70a6ce3b3d4bd5a3e0a2912 55 Pfam PF10013 Uncharacterized protein conserved in bacteria (DUF2256) 11 50 2.2E-19 T 29-03-2018 IPR017136 Uncharacterised conserved protein UCP037205 THSYN_RS29750 519002e40d9ad27f04b1b48453c449f1 87 Gene3D G3DSA:3.30.1360.20 3 83 2.8E-14 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 THSYN_RS29750 519002e40d9ad27f04b1b48453c449f1 87 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 3 80 1.0E-7 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 THSYN_RS29750 519002e40d9ad27f04b1b48453c449f1 87 SUPERFAMILY SSF55248 4 80 3.27E-13 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 THSYN_RS02365 ffd6310e2eeccfd4de0f5bd79999c52b 234 SMART SM00862 155 231 1.1E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS02365 ffd6310e2eeccfd4de0f5bd79999c52b 234 Gene3D G3DSA:1.10.10.10 128 234 1.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS02365 ffd6310e2eeccfd4de0f5bd79999c52b 234 SUPERFAMILY SSF46894 139 232 4.54E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS02365 ffd6310e2eeccfd4de0f5bd79999c52b 234 SMART SM00448 5 115 1.5E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS02365 ffd6310e2eeccfd4de0f5bd79999c52b 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 2.2E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS02365 ffd6310e2eeccfd4de0f5bd79999c52b 234 Pfam PF00072 Response regulator receiver domain 7 116 6.0E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS02365 ffd6310e2eeccfd4de0f5bd79999c52b 234 Gene3D G3DSA:3.40.50.2300 5 127 1.4E-33 T 29-03-2018 THSYN_RS02365 ffd6310e2eeccfd4de0f5bd79999c52b 234 SUPERFAMILY SSF52172 3 123 5.41E-40 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 SUPERFAMILY SSF55347 177 487 9.16E-108 T 29-03-2018 THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 4 487 8.9E-173 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 4 487 77.779 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 Gene3D G3DSA:3.30.360.10 189 488 3.7E-119 T 29-03-2018 THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 143 156 9.9E-46 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 219 236 9.9E-46 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 237 253 9.9E-46 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 328 354 9.9E-46 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 167 195 9.9E-46 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 8 187 6.7E-55 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 Gene3D G3DSA:3.40.50.720 2 188 5.2E-61 T 29-03-2018 THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 189 486 9.7E-110 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 SUPERFAMILY SSF51735 2 190 2.95E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS10140 3b8f3d4817ae58ccd7c3ec92ed6cbeeb 492 PIRSF PIRSF000110 1 489 3.1E-172 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THSYN_RS17965 19f1eb4aea02c7c5ce5906bd46a72143 526 Gene3D G3DSA:3.40.720.10 264 403 3.7E-32 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS17965 19f1eb4aea02c7c5ce5906bd46a72143 526 Gene3D G3DSA:3.40.720.10 34 263 4.2E-46 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS17965 19f1eb4aea02c7c5ce5906bd46a72143 526 Pfam PF14707 C-terminal region of aryl-sulfatase 406 507 1.7E-7 T 29-03-2018 THSYN_RS17965 19f1eb4aea02c7c5ce5906bd46a72143 526 Gene3D G3DSA:3.30.1120.10 404 500 6.4E-18 T 29-03-2018 THSYN_RS17965 19f1eb4aea02c7c5ce5906bd46a72143 526 Pfam PF00884 Sulfatase 38 368 7.0E-59 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THSYN_RS17965 19f1eb4aea02c7c5ce5906bd46a72143 526 SUPERFAMILY SSF53649 34 519 3.93E-118 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 505 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 447 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 486 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 SMART SM00304 232 284 5.7E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 Gene3D G3DSA:1.10.287.130 275 331 1.3E-9 T 29-03-2018 THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 Gene3D G3DSA:3.30.565.10 332 506 3.1E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 Pfam PF00672 HAMP domain 232 280 1.4E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 SMART SM00388 285 349 4.1E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 SUPERFAMILY SSF47384 269 347 2.75E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 SUPERFAMILY SSF158472 232 280 2.88E-8 T 29-03-2018 THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 397 505 1.1E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 Pfam PF00512 His Kinase A (phospho-acceptor) domain 285 344 3.0E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 SUPERFAMILY SSF55874 339 505 1.7E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02360 3b34f21894775ae835cffeee722f49e3 506 SMART SM00387 396 506 5.1E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS30730 81c8ad710e36870b9bbc8f54cd7ce959 1030 Gene3D G3DSA:3.40.50.10810 554 769 5.2E-52 T 29-03-2018 THSYN_RS30730 81c8ad710e36870b9bbc8f54cd7ce959 1030 Gene3D G3DSA:3.40.50.300 842 1005 4.0E-30 T 29-03-2018 THSYN_RS30730 81c8ad710e36870b9bbc8f54cd7ce959 1030 SMART SM00487 549 744 1.1E-27 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS30730 81c8ad710e36870b9bbc8f54cd7ce959 1030 Pfam PF00271 Helicase conserved C-terminal domain 853 967 3.1E-14 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS30730 81c8ad710e36870b9bbc8f54cd7ce959 1030 Pfam PF00176 SNF2 family N-terminal domain 572 837 2.1E-58 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THSYN_RS30730 81c8ad710e36870b9bbc8f54cd7ce959 1030 SUPERFAMILY SSF52540 771 1024 8.58E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30730 81c8ad710e36870b9bbc8f54cd7ce959 1030 SUPERFAMILY SSF52540 515 768 2.84E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30730 81c8ad710e36870b9bbc8f54cd7ce959 1030 SMART SM00490 882 967 1.9E-19 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS30730 81c8ad710e36870b9bbc8f54cd7ce959 1030 Pfam PF12419 SNF2 Helicase protein 373 512 1.1E-39 T 29-03-2018 IPR022138 Helicase SWF/SNF-related THSYN_RS00010 20b4b1803e9bcc2582a630ddecfe1c57 366 SUPERFAMILY SSF55979 1 116 3.85E-24 T 29-03-2018 THSYN_RS00010 20b4b1803e9bcc2582a630ddecfe1c57 366 Gene3D G3DSA:3.10.150.10 124 247 2.8E-27 T 29-03-2018 THSYN_RS00010 20b4b1803e9bcc2582a630ddecfe1c57 366 SUPERFAMILY SSF55979 127 244 4.92E-25 T 29-03-2018 THSYN_RS00010 20b4b1803e9bcc2582a630ddecfe1c57 366 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 118 8.4E-28 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS00010 20b4b1803e9bcc2582a630ddecfe1c57 366 PIRSF PIRSF000804 1 366 3.8E-101 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS00010 20b4b1803e9bcc2582a630ddecfe1c57 366 Pfam PF02767 DNA polymerase III beta subunit, central domain 129 243 9.1E-30 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS00010 20b4b1803e9bcc2582a630ddecfe1c57 366 Gene3D G3DSA:3.10.150.10 1 122 1.9E-24 T 29-03-2018 THSYN_RS00010 20b4b1803e9bcc2582a630ddecfe1c57 366 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 246 365 4.5E-31 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS00010 20b4b1803e9bcc2582a630ddecfe1c57 366 SUPERFAMILY SSF55979 246 366 5.38E-30 T 29-03-2018 THSYN_RS00010 20b4b1803e9bcc2582a630ddecfe1c57 366 SMART SM00480 17 362 3.2E-117 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS00010 20b4b1803e9bcc2582a630ddecfe1c57 366 Gene3D G3DSA:3.10.150.10 248 366 1.2E-23 T 29-03-2018 THSYN_RS00010 20b4b1803e9bcc2582a630ddecfe1c57 366 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 366 2.4E-91 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 Gene3D G3DSA:3.40.50.150 510 717 3.7E-38 T 29-03-2018 THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 Pfam PF02926 THUMP domain 47 155 2.1E-9 T 29-03-2018 IPR004114 THUMP domain GO:0003723 THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 SMART SM00981 58 156 2.3E-18 T 29-03-2018 IPR004114 THUMP domain GO:0003723 THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 310 316 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 517 672 6.2E-18 T 29-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 6 717 32.067 T 29-03-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 SUPERFAMILY SSF53335 409 717 2.31E-63 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 Gene3D G3DSA:3.40.50.150 162 389 2.9E-26 T 29-03-2018 THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 Gene3D G3DSA:3.30.750.80 405 509 3.0E-5 T 29-03-2018 THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 Pfam PF01170 Putative RNA methylase family UPF0020 164 378 1.3E-39 T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 SUPERFAMILY SSF53335 263 380 7.44E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 SUPERFAMILY SSF53335 149 223 7.44E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 201 212 - T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS11085 10fed6d6886dd8fe1d1631608d5d0a3f 717 PIRSF PIRSF037618 1 717 1.8E-280 T 29-03-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS24630 d2397687ed23cea7f6e2186e519bdb5b 239 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 40 191 2.4E-43 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24630 d2397687ed23cea7f6e2186e519bdb5b 239 SUPERFAMILY SSF143243 16 215 8.89E-54 T 29-03-2018 THSYN_RS24630 d2397687ed23cea7f6e2186e519bdb5b 239 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 12 198 34.794 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24630 d2397687ed23cea7f6e2186e519bdb5b 239 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 151 172 - T 29-03-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24630 d2397687ed23cea7f6e2186e519bdb5b 239 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 117 178 1.0E-21 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS02740 709da7110523e8ca1f9f841eead7f0f3 170 SUPERFAMILY SSF50630 23 157 6.65E-40 T 29-03-2018 IPR021109 Aspartic peptidase domain THSYN_RS02740 709da7110523e8ca1f9f841eead7f0f3 170 Pfam PF05618 Putative ATP-dependant zinc protease 24 159 2.3E-32 T 29-03-2018 THSYN_RS02740 709da7110523e8ca1f9f841eead7f0f3 170 Gene3D G3DSA:2.40.70.10 21 150 8.5E-31 T 29-03-2018 IPR021109 Aspartic peptidase domain THSYN_RS11685 fe708110f77f74a994b47c459169461c 222 SUPERFAMILY SSF52172 1 170 2.57E-35 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS11685 fe708110f77f74a994b47c459169461c 222 SMART SM00862 145 216 6.9E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS11685 fe708110f77f74a994b47c459169461c 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 8.6E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS11685 fe708110f77f74a994b47c459169461c 222 Pfam PF00072 Response regulator receiver domain 3 112 8.1E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS11685 fe708110f77f74a994b47c459169461c 222 Gene3D G3DSA:3.40.50.2300 1 116 1.6E-31 T 29-03-2018 THSYN_RS11685 fe708110f77f74a994b47c459169461c 222 Gene3D G3DSA:1.10.10.10 117 222 2.8E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS11685 fe708110f77f74a994b47c459169461c 222 SMART SM00448 1 112 9.3E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 190 9.9E-83 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 PRINTS PR00097 Anthranilate synthase component II signature 169 182 2.6E-36 T 29-03-2018 THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 PRINTS PR00097 Anthranilate synthase component II signature 99 107 2.6E-36 T 29-03-2018 THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.6E-36 T 29-03-2018 THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 PRINTS PR00097 Anthranilate synthase component II signature 74 85 2.6E-36 T 29-03-2018 THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 PRINTS PR00097 Anthranilate synthase component II signature 47 56 2.6E-36 T 29-03-2018 THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 PRINTS PR00097 Anthranilate synthase component II signature 119 131 2.6E-36 T 29-03-2018 THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 SUPERFAMILY SSF52317 2 191 1.45E-53 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 2.2E-13 T 29-03-2018 THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 2.2E-13 T 29-03-2018 THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 2.2E-13 T 29-03-2018 THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 Pfam PF00117 Glutamine amidotransferase class-I 4 190 5.1E-53 T 29-03-2018 IPR017926 Glutamine amidotransferase THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 7.3E-6 T 29-03-2018 THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 7.3E-6 T 29-03-2018 THSYN_RS26475 7cf5d3dc6c9dc46d2d53da25359358fd 193 Gene3D G3DSA:3.40.50.880 1 193 1.1E-57 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS19595 53c69cca4548578461e0e289ae8afa69 307 Gene3D G3DSA:1.10.3470.10 1 296 1.5E-56 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like THSYN_RS19595 53c69cca4548578461e0e289ae8afa69 307 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 291 5.8E-51 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THSYN_RS09340 90b3ea590129952c1b23992afd4eb87d 341 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 THSYN_RS09340 90b3ea590129952c1b23992afd4eb87d 341 Gene3D G3DSA:3.40.190.10 27 137 2.8E-21 T 29-03-2018 THSYN_RS09340 90b3ea590129952c1b23992afd4eb87d 341 SUPERFAMILY SSF53850 28 254 1.67E-37 T 29-03-2018 THSYN_RS09340 90b3ea590129952c1b23992afd4eb87d 341 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 251 4.1E-23 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS09340 90b3ea590129952c1b23992afd4eb87d 341 Gene3D G3DSA:3.40.190.10 138 228 7.4E-8 T 29-03-2018 THSYN_RS09340 90b3ea590129952c1b23992afd4eb87d 341 SMART SM00062 37 265 3.3E-27 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS05270 9f13348b6be1f7ad23d67722da146eff 212 Gene3D G3DSA:3.40.50.410 1 188 2.1E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS05270 9f13348b6be1f7ad23d67722da146eff 212 PIRSF PIRSF020634 3 211 4.5E-60 T 29-03-2018 IPR011392 Tellurite resistance, TerY THSYN_RS05270 9f13348b6be1f7ad23d67722da146eff 212 Pfam PF00092 von Willebrand factor type A domain 8 145 6.6E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS05270 9f13348b6be1f7ad23d67722da146eff 212 SUPERFAMILY SSF53300 5 163 4.3E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS05270 9f13348b6be1f7ad23d67722da146eff 212 SMART SM00327 5 184 3.2E-8 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 5 128 1.8E-42 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 Pfam PF00391 PEP-utilising enzyme, mobile domain 430 503 6.5E-21 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 Gene3D G3DSA:3.30.1340.10 164 247 2.2E-25 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 Pfam PF00381 PTS HPr component phosphorylation site 169 244 5.4E-24 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 PRINTS PR00107 Phosphocarrier protein signature 179 195 2.2E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 PRINTS PR00107 Phosphocarrier protein signature 219 236 2.2E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 PRINTS PR00107 Phosphocarrier protein signature 204 219 2.2E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 Gene3D G3DSA:1.10.274.10 307 423 1.6E-28 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 68 80 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 179 186 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 SUPERFAMILY SSF47831 313 422 4.45E-26 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 Gene3D G3DSA:2.70.70.10 1 151 8.8E-48 T 29-03-2018 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 169 244 2.9E-23 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 720 738 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 SUPERFAMILY SSF55594 171 254 1.14E-23 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 737 752 5.0E-22 T 29-03-2018 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 773 785 5.0E-22 T 29-03-2018 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 720 735 5.0E-22 T 29-03-2018 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 571 590 5.0E-22 T 29-03-2018 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 SUPERFAMILY SSF52009 405 522 2.62E-31 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 Pfam PF05524 PEP-utilising enzyme, N-terminal 287 405 7.1E-23 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 7 126 4.7E-37 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 538 812 4.1E-106 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 Gene3D G3DSA:3.50.30.10 424 522 4.5E-24 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 SUPERFAMILY SSF51621 538 822 1.62E-99 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 SUPERFAMILY SSF51261 2 145 1.59E-45 T 29-03-2018 IPR011055 Duplicated hybrid motif THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 286 838 2.3E-163 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 THSYN_RS16885 243855eb4f0626db3575c4ce3f0f8fdc 842 Gene3D G3DSA:3.20.20.60 527 840 7.0E-96 T 29-03-2018 THSYN_RS24015 ffe2f4f8c45a6852ca479e8c1afa29ec 177 Gene3D G3DSA:3.30.110.10 86 177 8.0E-35 T 29-03-2018 THSYN_RS24015 ffe2f4f8c45a6852ca479e8c1afa29ec 177 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 14 176 1.6E-69 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THSYN_RS24015 ffe2f4f8c45a6852ca479e8c1afa29ec 177 SUPERFAMILY SSF54364 12 85 1.11E-29 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THSYN_RS24015 ffe2f4f8c45a6852ca479e8c1afa29ec 177 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 90 175 5.3E-36 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 THSYN_RS24015 ffe2f4f8c45a6852ca479e8c1afa29ec 177 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 14 83 1.3E-30 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THSYN_RS24015 ffe2f4f8c45a6852ca479e8c1afa29ec 177 SUPERFAMILY SSF55200 91 176 1.24E-32 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 THSYN_RS24015 ffe2f4f8c45a6852ca479e8c1afa29ec 177 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 8 177 31.174 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THSYN_RS24015 ffe2f4f8c45a6852ca479e8c1afa29ec 177 ProSitePatterns PS00938 Initiation factor 3 signature. 65 78 - T 29-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 THSYN_RS24015 ffe2f4f8c45a6852ca479e8c1afa29ec 177 Gene3D G3DSA:3.10.20.80 9 85 8.5E-32 T 29-03-2018 THSYN_RS11175 581e2a05e30c2623b3db516f1cf721cb 436 Gene3D G3DSA:1.10.3290.10 64 330 4.8E-42 T 29-03-2018 IPR003812 Fido domain THSYN_RS11175 581e2a05e30c2623b3db516f1cf721cb 436 SUPERFAMILY SSF140931 131 325 3.66E-27 T 29-03-2018 IPR003812 Fido domain THSYN_RS11175 581e2a05e30c2623b3db516f1cf721cb 436 Pfam PF02661 Fic/DOC family 154 256 5.3E-16 T 29-03-2018 IPR003812 Fido domain THSYN_RS11175 581e2a05e30c2623b3db516f1cf721cb 436 Gene3D G3DSA:1.10.10.10 331 408 2.0E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 360 439 5.5E-28 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.5E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 2.5E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 90 2.5E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 155 1.4E-20 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 183 346 3.3E-26 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 Gene3D G3DSA:3.30.300.20 374 440 4.1E-27 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 SUPERFAMILY SSF52540 1 162 3.14E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 439 2.0E-167 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 SUPERFAMILY SSF52540 137 446 8.3E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 Hamap MF_00195 GTPase Der [der]. 2 442 37.223 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 Pfam PF01926 50S ribosome-binding GTPase 5 119 1.8E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 Pfam PF01926 50S ribosome-binding GTPase 185 303 3.6E-23 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 Gene3D G3DSA:1.20.120.430 3 66 4.0E-13 T 29-03-2018 THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 Gene3D G3DSA:1.20.120.430 253 373 3.4E-14 T 29-03-2018 THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 PIRSF PIRSF006485 1 447 1.4E-166 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 Gene3D G3DSA:1.20.120.430 67 252 1.5E-46 T 29-03-2018 THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 SMART SM00382 182 434 0.0021 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS07615 3b8a3efb66e880724a2a2580c90f944d 470 SMART SM00382 1 174 9.4 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS02030 c0eb92dcdae1924fe564673e3fdb7c8e 285 Pfam PF03668 P-loop ATPase protein family 1 284 6.4E-93 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 THSYN_RS02030 c0eb92dcdae1924fe564673e3fdb7c8e 285 Gene3D G3DSA:3.40.50.300 1 155 1.9E-10 T 29-03-2018 THSYN_RS02030 c0eb92dcdae1924fe564673e3fdb7c8e 285 SUPERFAMILY SSF52540 1 154 6.63E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02030 c0eb92dcdae1924fe564673e3fdb7c8e 285 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 285 37.92 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 THSYN_RS02030 c0eb92dcdae1924fe564673e3fdb7c8e 285 PIRSF PIRSF005052 1 285 1.1E-107 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 Pfam PF02254 TrkA-N domain 3 112 1.5E-25 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 Pfam PF02254 TrkA-N domain 234 349 6.8E-21 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 SUPERFAMILY SSF51735 231 375 7.44E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 SUPERFAMILY SSF51735 1 151 9.54E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 Gene3D G3DSA:3.30.70.1450 366 467 1.4E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 Pfam PF02080 TrkA-C domain 155 223 2.5E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 SUPERFAMILY SSF116726 135 221 1.96E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 SUPERFAMILY SSF116726 380 452 2.75E-5 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 Gene3D G3DSA:3.30.70.1450 139 231 1.1E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 Gene3D G3DSA:3.40.50.720 232 365 5.4E-18 T 29-03-2018 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 Gene3D G3DSA:3.40.50.720 1 138 1.8E-24 T 29-03-2018 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.3E-20 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.3E-20 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 1.3E-20 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.3E-20 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THSYN_RS00510 5fece6d81f0c3c75be1a522cf4433faa 467 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.3E-20 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THSYN_RS04190 3457b70b741395a5fb12b4bf1780b9ca 401 Pfam PF14238 Domain of unknown function (DUF4340) 84 258 8.6E-20 T 29-03-2018 IPR025641 Domain of unknown function DUF4340 THSYN_RS11830 1162a022c38ed1680a4a49e4b55b329e 617 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THSYN_RS11830 1162a022c38ed1680a4a49e4b55b329e 617 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 612 1.3E-241 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THSYN_RS11830 1162a022c38ed1680a4a49e4b55b329e 617 SUPERFAMILY SSF143975 3 422 1.12E-132 T 29-03-2018 THSYN_RS11830 1162a022c38ed1680a4a49e4b55b329e 617 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 511 522 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THSYN_RS11830 1162a022c38ed1680a4a49e4b55b329e 617 Pfam PF00920 Dehydratase family 34 609 3.1E-215 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THSYN_RS11830 1162a022c38ed1680a4a49e4b55b329e 617 Gene3D G3DSA:3.40.50.2300 90 253 0.001 T 29-03-2018 THSYN_RS11830 1162a022c38ed1680a4a49e4b55b329e 617 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 612 44.627 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THSYN_RS11830 1162a022c38ed1680a4a49e4b55b329e 617 SUPERFAMILY SSF52016 423 614 1.57E-56 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THSYN_RS21795 5013061f88ce9b28cce7a9e67665cbfe 463 PIRSF PIRSF000355 117 463 1.8E-136 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS21795 5013061f88ce9b28cce7a9e67665cbfe 463 Pfam PF00268 Ribonucleotide reductase, small chain 143 430 2.7E-83 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS21795 5013061f88ce9b28cce7a9e67665cbfe 463 Gene3D G3DSA:1.10.620.20 119 444 4.9E-98 T 29-03-2018 THSYN_RS21795 5013061f88ce9b28cce7a9e67665cbfe 463 SUPERFAMILY SSF47240 117 436 1.12E-97 T 29-03-2018 IPR009078 Ferritin-like superfamily THSYN_RS06630 874c246c54af6db590d645be0f51186e 253 Pfam PF05685 Putative restriction endonuclease 33 156 2.4E-16 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS06630 874c246c54af6db590d645be0f51186e 253 SUPERFAMILY SSF52980 7 167 6.97E-30 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS06630 874c246c54af6db590d645be0f51186e 253 Gene3D G3DSA:3.90.1570.10 19 155 1.1E-20 T 29-03-2018 THSYN_RS07740 78f503dac72b04e1d4cb0e9bf9320a54 433 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 32 336 1.7E-23 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS07740 78f503dac72b04e1d4cb0e9bf9320a54 433 Gene3D G3DSA:3.40.50.300 1 372 1.6E-30 T 29-03-2018 THSYN_RS07740 78f503dac72b04e1d4cb0e9bf9320a54 433 SUPERFAMILY SSF52540 1 341 4.05E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08420 a5318dfea6a6f7456c335661ba9b5b5e 624 SUPERFAMILY SSF51445 119 536 7.92E-98 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS08420 a5318dfea6a6f7456c335661ba9b5b5e 624 Pfam PF00128 Alpha amylase, catalytic domain 179 499 3.8E-74 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THSYN_RS08420 a5318dfea6a6f7456c335661ba9b5b5e 624 Gene3D G3DSA:2.60.40.10 1 115 4.6E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08420 a5318dfea6a6f7456c335661ba9b5b5e 624 PIRSF PIRSF036918 1 597 1.1E-214 T 29-03-2018 IPR017069 Maltodextrin glucosidase GO:0004558|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.20|KEGG: 00500+3.2.1.20|MetaCyc: PWY-842 THSYN_RS08420 a5318dfea6a6f7456c335661ba9b5b5e 624 SUPERFAMILY SSF81296 36 111 6.53E-8 T 29-03-2018 IPR014756 Immunoglobulin E-set THSYN_RS08420 a5318dfea6a6f7456c335661ba9b5b5e 624 SMART SM00642 130 527 1.8E-86 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THSYN_RS08420 a5318dfea6a6f7456c335661ba9b5b5e 624 Gene3D G3DSA:2.60.40.1180 533 618 2.2E-12 T 29-03-2018 THSYN_RS08420 a5318dfea6a6f7456c335661ba9b5b5e 624 Gene3D G3DSA:3.20.20.80 118 532 3.9E-96 T 29-03-2018 THSYN_RS08420 a5318dfea6a6f7456c335661ba9b5b5e 624 SUPERFAMILY SSF51011 536 616 1.23E-6 T 29-03-2018 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 Gene3D G3DSA:2.30.30.40 470 503 0.13 T 29-03-2018 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 Gene3D G3DSA:2.30.30.40 553 611 4.2E-7 T 29-03-2018 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 Gene3D G3DSA:3.40.50.2300 632 761 3.4E-34 T 29-03-2018 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 Pfam PF00072 Response regulator receiver domain 641 749 5.0E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 Gene3D G3DSA:2.40.50.180 504 552 8.8E-6 T 29-03-2018 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 SMART SM00387 325 469 2.8E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 SMART SM00073 5 102 4.8E-22 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 SUPERFAMILY SSF55874 282 467 7.6E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 384 5.7E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 466 5.7E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 5.7E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 Gene3D G3DSA:1.10.287.560 176 290 1.6E-6 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 SUPERFAMILY SSF47226 5 125 2.62E-32 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 SMART SM00448 639 753 1.3E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 SUPERFAMILY SSF52172 638 758 6.83E-33 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 Gene3D G3DSA:3.30.565.10 291 469 1.8E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 SUPERFAMILY SSF50341 463 614 2.75E-21 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 SMART SM01231 176 280 0.0012 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 Pfam PF01584 CheW-like domain 474 613 7.6E-18 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 328 468 7.5E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 Pfam PF01627 Hpt domain 8 100 3.3E-19 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 SMART SM00260 461 611 1.0E-14 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS04365 2ac31ba61961326f39e2a9da0094e4f7 761 Gene3D G3DSA:1.20.120.160 1 148 2.9E-34 T 29-03-2018 THSYN_RS20625 806c7ddf81b7a36e1896b62a1fbb52ab 455 Gene3D G3DSA:1.10.10.60 410 454 3.3E-14 T 29-03-2018 THSYN_RS20625 806c7ddf81b7a36e1896b62a1fbb52ab 455 Gene3D G3DSA:3.40.50.2300 1 152 1.1E-38 T 29-03-2018 THSYN_RS20625 806c7ddf81b7a36e1896b62a1fbb52ab 455 SMART SM00382 162 301 0.0016 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS20625 806c7ddf81b7a36e1896b62a1fbb52ab 455 SUPERFAMILY SSF52172 2 186 7.12E-46 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS20625 806c7ddf81b7a36e1896b62a1fbb52ab 455 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 223 238 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THSYN_RS20625 806c7ddf81b7a36e1896b62a1fbb52ab 455 SMART SM00448 4 116 1.4E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS20625 806c7ddf81b7a36e1896b62a1fbb52ab 455 Pfam PF00158 Sigma-54 interaction domain 143 303 1.1E-44 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THSYN_RS20625 806c7ddf81b7a36e1896b62a1fbb52ab 455 Gene3D G3DSA:1.10.8.60 310 409 5.0E-16 T 29-03-2018 THSYN_RS20625 806c7ddf81b7a36e1896b62a1fbb52ab 455 Pfam PF00072 Response regulator receiver domain 6 114 3.2E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS20625 806c7ddf81b7a36e1896b62a1fbb52ab 455 SUPERFAMILY SSF52540 143 379 2.0E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS20625 806c7ddf81b7a36e1896b62a1fbb52ab 455 Gene3D G3DSA:3.40.50.300 153 309 1.3E-23 T 29-03-2018 THSYN_RS20625 806c7ddf81b7a36e1896b62a1fbb52ab 455 Pfam PF02954 Bacterial regulatory protein, Fis family 407 445 1.3E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS20625 806c7ddf81b7a36e1896b62a1fbb52ab 455 SUPERFAMILY SSF46689 350 449 9.41E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS26085 d485d2d843d1efc050942b259d235c90 561 SUPERFAMILY SSF52540 1 217 2.95E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26085 d485d2d843d1efc050942b259d235c90 561 Pfam PF02463 RecF/RecN/SMC N terminal domain 14 508 4.2E-17 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal THSYN_RS26085 d485d2d843d1efc050942b259d235c90 561 PIRSF PIRSF003128 1 557 7.5E-158 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 THSYN_RS26085 d485d2d843d1efc050942b259d235c90 561 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 552 2.1E-161 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 THSYN_RS26085 d485d2d843d1efc050942b259d235c90 561 SUPERFAMILY SSF52540 362 508 8.51E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26085 d485d2d843d1efc050942b259d235c90 561 SUPERFAMILY SSF52540 3 50 8.51E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26085 d485d2d843d1efc050942b259d235c90 561 Gene3D G3DSA:3.40.50.300 1 532 2.1E-39 T 29-03-2018 THSYN_RS00565 def8669bfe6290bd5a6597d3567da7cc 150 SUPERFAMILY SSF52172 25 144 1.99E-27 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS00565 def8669bfe6290bd5a6597d3567da7cc 150 Gene3D G3DSA:3.40.50.2300 18 149 1.8E-27 T 29-03-2018 THSYN_RS00565 def8669bfe6290bd5a6597d3567da7cc 150 Pfam PF00072 Response regulator receiver domain 27 139 2.3E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00565 def8669bfe6290bd5a6597d3567da7cc 150 SMART SM00448 25 140 2.6E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS10960 56218bd2921ab79b49230220c16a0e22 226 Gene3D G3DSA:2.60.120.260 20 199 0.0016 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 SUPERFAMILY SSF48452 273 402 8.86E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 Pfam PF14559 Tetratricopeptide repeat 561 623 1.2E-5 T 29-03-2018 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 Pfam PF14559 Tetratricopeptide repeat 457 516 1.6E-6 T 29-03-2018 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 Gene3D G3DSA:1.25.40.10 328 406 1.1E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 Gene3D G3DSA:1.25.40.10 306 327 0.0088 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 Gene3D G3DSA:1.25.40.10 407 461 4.2E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 SMART SM00028 581 614 31.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 SMART SM00028 445 478 13.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 SMART SM00028 242 275 220.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 SMART SM00028 513 547 36.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 SMART SM00028 174 207 65.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 SMART SM00028 479 512 1.6 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 SMART SM00028 410 443 190.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 SUPERFAMILY SSF48452 159 301 7.99E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 Gene3D G3DSA:1.25.40.10 217 305 2.9E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 Gene3D G3DSA:1.25.40.10 559 624 1.4E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 Gene3D G3DSA:1.25.40.10 462 536 1.4E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 SUPERFAMILY SSF48452 446 617 1.61E-27 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 Gene3D G3DSA:1.25.40.10 537 558 9.6E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 Pfam PF13432 Tetratricopeptide repeat 283 344 1.4E-6 T 29-03-2018 THSYN_RS27635 a6c258e6d230e01ea1fde0a9ad0b1873 654 Gene3D G3DSA:1.25.40.10 77 216 1.7E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 SMART SM00091 34 101 0.0015 T 29-03-2018 IPR000014 PAS domain THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 SMART SM00388 198 265 5.6E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 363 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 377 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 401 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 420 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 SMART SM00086 122 164 4.8E-4 T 29-03-2018 IPR001610 PAC motif THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 Gene3D G3DSA:3.40.50.2300 446 578 5.1E-31 T 29-03-2018 THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 SUPERFAMILY SSF55785 37 156 1.06E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 Pfam PF13426 PAS domain 48 162 1.4E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 SMART SM00387 311 423 4.3E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 SMART SM00448 449 563 6.2E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 Gene3D G3DSA:3.30.565.10 259 423 2.2E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 Gene3D G3DSA:1.10.287.130 189 258 1.0E-16 T 29-03-2018 THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 38 170 1.7E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 SUPERFAMILY SSF47384 184 266 5.3E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 SUPERFAMILY SSF52172 450 570 6.69E-31 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 Pfam PF00512 His Kinase A (phospho-acceptor) domain 198 265 4.9E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 Pfam PF00072 Response regulator receiver domain 452 563 1.2E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 SUPERFAMILY SSF55874 254 420 2.1E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 422 5.7E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS15200 594cee96517b3e89f18c9c2f0d877767 579 Gene3D G3DSA:3.30.450.20 18 182 1.1E-17 T 29-03-2018 THSYN_RS12730 756a19484279c02d831810b4cb8ab48e 328 Pfam PF01218 Coproporphyrinogen III oxidase 10 311 3.6E-124 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THSYN_RS12730 756a19484279c02d831810b4cb8ab48e 328 SUPERFAMILY SSF102886 6 311 4.97E-130 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THSYN_RS12730 756a19484279c02d831810b4cb8ab48e 328 PRINTS PR00073 Coprogen oxidase signature 272 298 2.2E-83 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THSYN_RS12730 756a19484279c02d831810b4cb8ab48e 328 PRINTS PR00073 Coprogen oxidase signature 32 48 2.2E-83 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THSYN_RS12730 756a19484279c02d831810b4cb8ab48e 328 PRINTS PR00073 Coprogen oxidase signature 91 115 2.2E-83 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THSYN_RS12730 756a19484279c02d831810b4cb8ab48e 328 PRINTS PR00073 Coprogen oxidase signature 163 192 2.2E-83 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THSYN_RS12730 756a19484279c02d831810b4cb8ab48e 328 PRINTS PR00073 Coprogen oxidase signature 244 271 2.2E-83 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THSYN_RS12730 756a19484279c02d831810b4cb8ab48e 328 PRINTS PR00073 Coprogen oxidase signature 126 148 2.2E-83 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THSYN_RS12730 756a19484279c02d831810b4cb8ab48e 328 PRINTS PR00073 Coprogen oxidase signature 49 70 2.2E-83 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THSYN_RS12730 756a19484279c02d831810b4cb8ab48e 328 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 167 191 - T 29-03-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THSYN_RS12730 756a19484279c02d831810b4cb8ab48e 328 Gene3D G3DSA:3.40.1500.10 2 312 1.1E-130 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THSYN_RS12730 756a19484279c02d831810b4cb8ab48e 328 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 4 287 54.847 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THSYN_RS12730 756a19484279c02d831810b4cb8ab48e 328 PIRSF PIRSF000166 3 313 1.7E-118 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THSYN_RS29210 b5bd5e8ec22c13725e92411addde9b63 514 Pfam PF00884 Sulfatase 16 350 3.5E-74 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THSYN_RS29210 b5bd5e8ec22c13725e92411addde9b63 514 Gene3D G3DSA:3.40.720.10 248 386 3.4E-20 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS29210 b5bd5e8ec22c13725e92411addde9b63 514 Gene3D G3DSA:3.40.720.10 12 247 2.0E-43 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS29210 b5bd5e8ec22c13725e92411addde9b63 514 SUPERFAMILY SSF53649 13 478 1.74E-88 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS29210 b5bd5e8ec22c13725e92411addde9b63 514 ProSitePatterns PS00149 Sulfatases signature 2. 110 120 - T 29-03-2018 IPR024607 Sulfatase, conserved site THSYN_RS15440 df83a2d515672563d4a90feb4318e556 153 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 7 152 3.5E-28 T 29-03-2018 IPR011747 Conserved hypothetical protein CHP02241 THSYN_RS15440 df83a2d515672563d4a90feb4318e556 153 Pfam PF06841 T4-like virus tail tube protein gp19 11 151 1.3E-31 T 29-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 Gene3D G3DSA:1.10.287.130 422 480 2.1E-15 T 29-03-2018 THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 Pfam PF00512 His Kinase A (phospho-acceptor) domain 417 482 1.3E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 SUPERFAMILY SSF55785 254 383 2.62E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 Pfam PF08447 PAS fold 293 379 1.6E-9 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 Pfam PF00672 HAMP domain 193 242 2.8E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 525 634 7.2E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 SMART SM00304 193 245 2.7E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 SUPERFAMILY SSF158472 193 243 1.44E-10 T 29-03-2018 THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 SMART SM00086 343 385 3.1E-5 T 29-03-2018 IPR001610 PAC motif THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 SMART SM00388 416 484 6.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 SUPERFAMILY SSF55874 485 637 1.01E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 SUPERFAMILY SSF47384 400 485 1.47E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 Gene3D G3DSA:3.30.565.10 486 645 2.0E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 PRINTS PR00344 Bacterial sensor protein C-terminal signature 564 578 2.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 PRINTS PR00344 Bacterial sensor protein C-terminal signature 621 634 2.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 PRINTS PR00344 Bacterial sensor protein C-terminal signature 582 592 2.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 PRINTS PR00344 Bacterial sensor protein C-terminal signature 597 615 2.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 SMART SM00387 525 637 1.2E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS25870 3e9f2123c4650579a8b86d370fcb6e48 649 Gene3D G3DSA:3.30.450.20 264 421 4.5E-23 T 29-03-2018 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 Gene3D G3DSA:1.10.601.10 3 189 1.0E-61 T 29-03-2018 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 SUPERFAMILY SSF88659 193 267 1.44E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 SUPERFAMILY SSF88659 251 346 2.43E-23 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 8 354 39.756 T 29-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 Pfam PF04539 Sigma-70 region 3 200 274 2.0E-16 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 Gene3D G3DSA:1.10.10.10 190 240 2.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 144 157 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 SUPERFAMILY SSF88946 82 190 4.58E-46 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 80 353 1.1E-129 T 29-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 PRINTS PR00046 Major sigma-70 factor signature 313 328 4.8E-26 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 PRINTS PR00046 Major sigma-70 factor signature 292 304 4.8E-26 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 PRINTS PR00046 Major sigma-70 factor signature 144 157 4.8E-26 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 PRINTS PR00046 Major sigma-70 factor signature 168 176 4.8E-26 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 PRINTS PR00046 Major sigma-70 factor signature 328 339 4.8E-26 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 116 342 1.1E-35 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 Pfam PF00140 Sigma-70 factor, region 1.2 82 114 3.8E-12 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 Gene3D G3DSA:1.10.10.10 284 355 2.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 Pfam PF04542 Sigma-70 region 2 121 189 5.3E-21 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS08840 d4994ab8f177cbf31003772876cc6543 355 Pfam PF04545 Sigma-70, region 4 288 341 4.1E-16 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS14540 faefcd40630a8e353613a15cbe71440b 157 Gene3D G3DSA:3.30.160.70 1 64 1.1E-6 T 29-03-2018 THSYN_RS14540 faefcd40630a8e353613a15cbe71440b 157 Gene3D G3DSA:1.10.10.10 65 157 6.9E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS14540 faefcd40630a8e353613a15cbe71440b 157 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 67 148 3.3E-26 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 THSYN_RS14540 faefcd40630a8e353613a15cbe71440b 157 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 69 150 2.6E-29 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 THSYN_RS14540 faefcd40630a8e353613a15cbe71440b 157 SUPERFAMILY SSF46767 66 150 4.58E-26 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 THSYN_RS14540 faefcd40630a8e353613a15cbe71440b 157 SUPERFAMILY SSF53155 3 72 4.71E-10 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 THSYN_RS14540 faefcd40630a8e353613a15cbe71440b 157 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 115 121 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 THSYN_RS11010 a7fa95ca8f75416ff7e063c8e78952ae 226 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 119 3.6E-22 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THSYN_RS11010 a7fa95ca8f75416ff7e063c8e78952ae 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 224 3.1E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS11010 a7fa95ca8f75416ff7e063c8e78952ae 226 SUPERFAMILY SSF161098 16 216 2.88E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS11010 a7fa95ca8f75416ff7e063c8e78952ae 226 Gene3D G3DSA:1.10.3720.10 2 226 6.5E-39 T 29-03-2018 THSYN_RS22880 e396de2538f75b01dfed3068a8b1fa0c 596 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 520 5.0E-129 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS22880 e396de2538f75b01dfed3068a8b1fa0c 596 SUPERFAMILY SSF56235 1 225 1.8E-61 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS22880 e396de2538f75b01dfed3068a8b1fa0c 596 PIRSF PIRSF001589 1 596 1.3E-195 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS22880 e396de2538f75b01dfed3068a8b1fa0c 596 Gene3D G3DSA:3.60.20.10 1 222 3.5E-56 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS22880 e396de2538f75b01dfed3068a8b1fa0c 596 Pfam PF00733 Asparagine synthase 243 587 7.1E-82 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THSYN_RS22880 e396de2538f75b01dfed3068a8b1fa0c 596 TIGRFAM TIGR03104 trio_amidotrans: asparagine synthase family amidotransferase 1 588 2.6E-288 T 29-03-2018 IPR017535 Asparagine synthase family amidotransferase THSYN_RS22880 e396de2538f75b01dfed3068a8b1fa0c 596 Pfam PF13537 Glutamine amidotransferase domain 47 167 8.1E-45 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain THSYN_RS22880 e396de2538f75b01dfed3068a8b1fa0c 596 Gene3D G3DSA:3.40.50.620 223 593 5.4E-70 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS22880 e396de2538f75b01dfed3068a8b1fa0c 596 SUPERFAMILY SSF52402 234 387 6.62E-71 T 29-03-2018 THSYN_RS22880 e396de2538f75b01dfed3068a8b1fa0c 596 SUPERFAMILY SSF52402 442 564 6.62E-71 T 29-03-2018 THSYN_RS19795 fb66fb788566b33b145c716f766c7162 300 Gene3D G3DSA:3.40.50.1100 44 139 8.6E-35 T 29-03-2018 THSYN_RS19795 fb66fb788566b33b145c716f766c7162 300 Gene3D G3DSA:3.40.50.1100 140 300 3.8E-40 T 29-03-2018 THSYN_RS19795 fb66fb788566b33b145c716f766c7162 300 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 36 54 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 THSYN_RS19795 fb66fb788566b33b145c716f766c7162 300 TIGRFAM TIGR01138 cysM: cysteine synthase B 9 298 1.9E-137 T 29-03-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 THSYN_RS19795 fb66fb788566b33b145c716f766c7162 300 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 12 287 1.6E-62 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THSYN_RS19795 fb66fb788566b33b145c716f766c7162 300 TIGRFAM TIGR01136 cysKM: cysteine synthase 10 298 7.2E-116 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 THSYN_RS19795 fb66fb788566b33b145c716f766c7162 300 SUPERFAMILY SSF53686 9 298 2.1E-86 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THSYN_RS13440 d06fc76b8e8454d041925feb313029f5 810 SUPERFAMILY SSF47819 622 704 3.27E-13 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 THSYN_RS13440 d06fc76b8e8454d041925feb313029f5 810 Gene3D G3DSA:1.10.150.80 612 707 1.6E-16 T 29-03-2018 THSYN_RS13440 d06fc76b8e8454d041925feb313029f5 810 Pfam PF02689 Helicase 357 433 7.0E-5 T 29-03-2018 IPR003840 DNA helicase GO:0004386|GO:0005524 THSYN_RS13440 d06fc76b8e8454d041925feb313029f5 810 Gene3D G3DSA:3.40.50.300 154 404 4.6E-14 T 29-03-2018 THSYN_RS13440 d06fc76b8e8454d041925feb313029f5 810 Gene3D G3DSA:3.40.50.300 3 153 4.8E-11 T 29-03-2018 THSYN_RS13440 d06fc76b8e8454d041925feb313029f5 810 SMART SM00382 16 186 7.4E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS13440 d06fc76b8e8454d041925feb313029f5 810 Gene3D G3DSA:1.20.1050.10 486 554 0.001 T 29-03-2018 THSYN_RS13440 d06fc76b8e8454d041925feb313029f5 810 SUPERFAMILY SSF52540 3 212 5.84E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13440 d06fc76b8e8454d041925feb313029f5 810 SMART SM00341 621 704 4.4E-12 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 THSYN_RS13440 d06fc76b8e8454d041925feb313029f5 810 SUPERFAMILY SSF52540 130 428 3.05E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13440 d06fc76b8e8454d041925feb313029f5 810 Pfam PF00570 HRDC domain 626 693 3.7E-15 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 THSYN_RS13440 d06fc76b8e8454d041925feb313029f5 810 Pfam PF05970 PIF1-like helicase 19 211 3.2E-27 T 29-03-2018 IPR010285 DNA helicase Pif1-like GO:0000723|GO:0003678|GO:0006281 THSYN_RS13440 d06fc76b8e8454d041925feb313029f5 810 Pfam PF14493 Helix-turn-helix domain 716 803 3.6E-21 T 29-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 THSYN_RS29860 12867cceddd4c1f183f76f88011df0e1 569 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 438 457 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 THSYN_RS29860 12867cceddd4c1f183f76f88011df0e1 569 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 21 187 1.2E-38 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THSYN_RS29860 12867cceddd4c1f183f76f88011df0e1 569 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 403 544 3.6E-24 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THSYN_RS29860 12867cceddd4c1f183f76f88011df0e1 569 Gene3D G3DSA:3.40.50.1220 210 363 6.6E-30 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS29860 12867cceddd4c1f183f76f88011df0e1 569 Gene3D G3DSA:3.40.50.970 369 554 3.8E-34 T 29-03-2018 THSYN_RS29860 12867cceddd4c1f183f76f88011df0e1 569 Gene3D G3DSA:3.40.50.970 13 209 7.3E-45 T 29-03-2018 THSYN_RS29860 12867cceddd4c1f183f76f88011df0e1 569 SUPERFAMILY SSF52518 379 566 7.86E-47 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS29860 12867cceddd4c1f183f76f88011df0e1 569 SUPERFAMILY SSF52467 179 358 3.74E-28 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS29860 12867cceddd4c1f183f76f88011df0e1 569 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 218 312 3.3E-17 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 THSYN_RS29860 12867cceddd4c1f183f76f88011df0e1 569 PIRSF PIRSF036565 17 567 1.5E-148 T 29-03-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 THSYN_RS29860 12867cceddd4c1f183f76f88011df0e1 569 SUPERFAMILY SSF52518 21 193 1.25E-40 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS22875 6d3ac4ec810cda53e3d1f7471296bd42 193 SUPERFAMILY SSF46609 1 83 1.44E-35 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS22875 6d3ac4ec810cda53e3d1f7471296bd42 193 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS22875 6d3ac4ec810cda53e3d1f7471296bd42 193 PIRSF PIRSF000349 1 193 9.7E-84 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS22875 6d3ac4ec810cda53e3d1f7471296bd42 193 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 9.5E-40 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS22875 6d3ac4ec810cda53e3d1f7471296bd42 193 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 82 6.6E-33 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS22875 6d3ac4ec810cda53e3d1f7471296bd42 193 SUPERFAMILY SSF54719 82 191 7.2E-45 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS22875 6d3ac4ec810cda53e3d1f7471296bd42 193 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 3.8E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS22875 6d3ac4ec810cda53e3d1f7471296bd42 193 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 3.8E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS22875 6d3ac4ec810cda53e3d1f7471296bd42 193 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 3.8E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS22875 6d3ac4ec810cda53e3d1f7471296bd42 193 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 3.8E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS22875 6d3ac4ec810cda53e3d1f7471296bd42 193 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 3.8E-22 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 THSYN_RS22875 6d3ac4ec810cda53e3d1f7471296bd42 193 Gene3D G3DSA:1.10.287.990 20 82 1.6E-26 T 29-03-2018 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 Gene3D G3DSA:3.30.450.20 298 429 1.8E-31 T 29-03-2018 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 SMART SM00388 450 515 5.2E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 SMART SM00086 89 131 4.8E-11 T 29-03-2018 IPR001610 PAC motif THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 SMART SM00086 370 412 1.4E-10 T 29-03-2018 IPR001610 PAC motif THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 136 2.1E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 294 418 1.5E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 Pfam PF08447 PAS fold 39 124 5.4E-19 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 Pfam PF08447 PAS fold 322 405 5.2E-17 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 SUPERFAMILY SSF47384 435 516 6.08E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 Gene3D G3DSA:3.30.565.10 519 690 1.0E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 SUPERFAMILY SSF55785 22 134 1.93E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 SMART SM00448 710 823 2.5E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 SUPERFAMILY SSF52172 708 829 9.96E-38 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 Gene3D G3DSA:3.40.50.2300 705 832 2.5E-39 T 29-03-2018 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 Pfam PF00072 Response regulator receiver domain 713 822 1.9E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 Gene3D G3DSA:3.30.450.20 14 136 9.6E-30 T 29-03-2018 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 SUPERFAMILY SSF55785 285 410 1.01E-26 T 29-03-2018 IPR000014 PAS domain THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 SMART SM00091 15 84 2.3E-4 T 29-03-2018 IPR000014 PAS domain THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 SMART SM00091 298 364 3.1E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 SUPERFAMILY SSF55781 152 297 3.34E-13 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 PRINTS PR00344 Bacterial sensor protein C-terminal signature 667 680 5.5E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 PRINTS PR00344 Bacterial sensor protein C-terminal signature 608 622 5.5E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 PRINTS PR00344 Bacterial sensor protein C-terminal signature 643 661 5.5E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 SMART SM00387 561 683 2.2E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 561 682 1.3E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 Gene3D G3DSA:1.10.287.130 440 511 2.0E-18 T 29-03-2018 THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 SUPERFAMILY SSF55874 505 678 6.68E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 Gene3D G3DSA:3.30.450.40 137 297 6.6E-13 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS26335 b73f658ef4b7d77fb23867f3c0391400 832 Pfam PF00512 His Kinase A (phospho-acceptor) domain 450 515 4.6E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 Gene3D G3DSA:1.10.287.130 423 497 2.6E-18 T 29-03-2018 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 SUPERFAMILY SSF47384 418 502 5.89E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 Gene3D G3DSA:3.40.50.2300 687 812 3.5E-43 T 29-03-2018 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 Pfam PF00989 PAS fold 271 384 1.3E-12 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 SMART SM00448 689 802 2.7E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 SMART SM00387 547 661 3.9E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 547 658 3.5E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 PRINTS PR00344 Bacterial sensor protein C-terminal signature 621 639 7.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 600 7.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 PRINTS PR00344 Bacterial sensor protein C-terminal signature 604 614 7.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 PRINTS PR00344 Bacterial sensor protein C-terminal signature 645 658 7.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 Pfam PF00512 His Kinase A (phospho-acceptor) domain 433 500 2.4E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 Gene3D G3DSA:3.30.450.20 250 406 8.5E-30 T 29-03-2018 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 SUPERFAMILY SSF55785 257 384 1.33E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 Gene3D G3DSA:3.30.565.10 505 670 1.4E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 SUPERFAMILY SSF55874 490 659 1.44E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 Pfam PF00072 Response regulator receiver domain 691 802 4.0E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 SUPERFAMILY SSF158472 209 258 3.01E-7 T 29-03-2018 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 SMART SM00304 209 261 8.2E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 SMART SM00091 268 335 3.8E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 SMART SM00388 433 501 5.7E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 SUPERFAMILY SSF52172 686 810 3.13E-41 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS12380 1bdc32ce02398facff62a58d3bfde823 812 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 264 395 1.9E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS13570 8f36eccfbd6761b0c5242af8928e9f11 619 SMART SM00853 432 575 7.2E-49 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 THSYN_RS13570 8f36eccfbd6761b0c5242af8928e9f11 619 Gene3D G3DSA:3.30.230.10 207 329 2.3E-30 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS13570 8f36eccfbd6761b0c5242af8928e9f11 619 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 311 2.3E-94 T 29-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 THSYN_RS13570 8f36eccfbd6761b0c5242af8928e9f11 619 SUPERFAMILY SSF118116 428 617 1.57E-57 T 29-03-2018 THSYN_RS13570 8f36eccfbd6761b0c5242af8928e9f11 619 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 29-03-2018 IPR014762 DNA mismatch repair, conserved site THSYN_RS13570 8f36eccfbd6761b0c5242af8928e9f11 619 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 615 28.361 T 29-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 THSYN_RS13570 8f36eccfbd6761b0c5242af8928e9f11 619 SUPERFAMILY SSF55874 2 201 6.29E-52 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS13570 8f36eccfbd6761b0c5242af8928e9f11 619 SMART SM01340 213 331 5.5E-55 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 THSYN_RS13570 8f36eccfbd6761b0c5242af8928e9f11 619 Gene3D G3DSA:3.30.565.10 2 197 2.9E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS13570 8f36eccfbd6761b0c5242af8928e9f11 619 Pfam PF08676 MutL C terminal dimerisation domain 428 575 2.4E-45 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 THSYN_RS13570 8f36eccfbd6761b0c5242af8928e9f11 619 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 215 330 4.8E-37 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 THSYN_RS13570 8f36eccfbd6761b0c5242af8928e9f11 619 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 117 2.5E-8 T 29-03-2018 THSYN_RS13570 8f36eccfbd6761b0c5242af8928e9f11 619 SUPERFAMILY SSF54211 193 330 3.22E-35 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 6.5E-224 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 1.3E-33 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 Gene3D G3DSA:2.40.30.10 208 301 8.8E-32 T 29-03-2018 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.56 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 SUPERFAMILY SSF50447 207 303 2.95E-30 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 SUPERFAMILY SSF52540 6 221 3.75E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 Gene3D G3DSA:3.40.50.300 75 205 1.9E-29 T 29-03-2018 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.9E-59 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 Gene3D G3DSA:3.40.50.300 2 74 3.1E-11 T 29-03-2018 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 151 8.2E-15 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 Gene3D G3DSA:2.40.30.10 302 395 6.6E-34 T 29-03-2018 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 5.1E-16 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THSYN_RS05680 90ff548f65f0eeadd9a512e0df43cf07 396 SUPERFAMILY SSF50465 304 396 2.48E-37 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 6.5E-224 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 1.3E-33 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 Gene3D G3DSA:2.40.30.10 208 301 8.8E-32 T 29-03-2018 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.56 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 SUPERFAMILY SSF50447 207 303 2.95E-30 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 SUPERFAMILY SSF52540 6 221 3.75E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 Gene3D G3DSA:3.40.50.300 75 205 1.9E-29 T 29-03-2018 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.9E-59 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 Gene3D G3DSA:3.40.50.300 2 74 3.1E-11 T 29-03-2018 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 151 8.2E-15 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 Gene3D G3DSA:2.40.30.10 302 395 6.6E-34 T 29-03-2018 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 5.1E-16 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THSYN_RS23925 90ff548f65f0eeadd9a512e0df43cf07 396 SUPERFAMILY SSF50465 304 396 2.48E-37 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 184 6.1E-5 T 29-03-2018 THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 244 1.9E-98 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.0E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.0E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.0E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 SUPERFAMILY SSF51735 4 245 5.41E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 243 5.2E-64 T 29-03-2018 THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 6.2E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 6.2E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 6.2E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.2E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.2E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.2E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 Gene3D G3DSA:3.40.50.720 39 246 1.5E-70 T 29-03-2018 THSYN_RS16195 e8d90b32b2233d0bf7f048953160161d 246 Gene3D G3DSA:3.40.50.720 1 38 2.6E-7 T 29-03-2018 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 Pfam PF08477 Ras of Complex, Roc, domain of DAPkinase 350 467 6.9E-21 T 29-03-2018 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 Pfam PF16095 C-terminal of Roc, COR, domain 523 718 3.1E-49 T 29-03-2018 IPR032171 C-terminal of Roc (COR) domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 Pfam PF13676 TIR domain 848 951 2.4E-10 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 Gene3D G3DSA:3.80.10.10 42 130 5.8E-10 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 Gene3D G3DSA:3.30.70.1390 347 423 8.9E-15 T 29-03-2018 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 SUPERFAMILY SSF52540 348 466 2.9E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 SUPERFAMILY SSF52047 67 298 2.55E-35 T 29-03-2018 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 Gene3D G3DSA:3.40.50.10140 843 955 5.1E-8 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 SUPERFAMILY SSF52200 844 953 4.32E-6 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 Gene3D G3DSA:3.80.10.10 184 297 4.4E-12 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 PRINTS PR00449 Transforming protein P21 ras signature 349 370 2.4E-7 T 29-03-2018 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 PRINTS PR00449 Transforming protein P21 ras signature 393 415 2.4E-7 T 29-03-2018 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 SMART SM00368 224 248 77.0 T 29-03-2018 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 SMART SM00368 124 148 8.5 T 29-03-2018 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 SMART SM00368 149 173 8.6 T 29-03-2018 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 SMART SM00368 96 123 1.4 T 29-03-2018 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 SMART SM00368 196 223 0.14 T 29-03-2018 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 Gene3D G3DSA:3.40.50.2000 131 183 9.4E-12 T 29-03-2018 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 Pfam PF13516 Leucine Rich repeat 149 165 0.013 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 Pfam PF13516 Leucine Rich repeat 124 142 0.48 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 Pfam PF13516 Leucine Rich repeat 199 218 0.46 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 THSYN_RS01650 9872bf77595d86196dfbc2cb0c97dd12 983 Pfam PF13516 Leucine Rich repeat 98 118 0.041 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 SUPERFAMILY SSF54001 243 265 1.21E-10 T 29-03-2018 THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 SUPERFAMILY SSF54001 141 198 1.21E-10 T 29-03-2018 THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 Gene3D G3DSA:2.60.40.10 1435 1526 0.012 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 Gene3D G3DSA:3.40.1850.10 2490 2588 9.2E-16 T 29-03-2018 THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 Gene3D G3DSA:3.40.1850.10 2589 2682 9.7E-14 T 29-03-2018 THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 Gene3D G3DSA:3.40.1850.10 2286 2387 7.6E-19 T 29-03-2018 THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 Gene3D G3DSA:3.40.1850.10 2388 2489 5.1E-19 T 29-03-2018 THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 Pfam PF01841 Transglutaminase-like superfamily 130 260 2.3E-10 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 SUPERFAMILY SSF49299 2576 2673 6.87E-5 T 29-03-2018 IPR000601 PKD domain THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 SUPERFAMILY SSF49785 1286 1433 3.72E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 Gene3D G3DSA:2.60.120.260 1288 1431 7.8E-10 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 Gene3D G3DSA:2.60.40.10 2062 2160 3.8E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 Gene3D G3DSA:2.60.40.10 1161 1266 0.0069 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 Gene3D G3DSA:2.60.40.10 1951 2057 1.7E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 Gene3D G3DSA:2.60.40.10 1863 1941 0.046 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 Gene3D G3DSA:2.60.40.10 815 924 1.3E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 Gene3D G3DSA:2.60.40.10 942 1039 0.017 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 SMART SM00089 2379 2472 4.3 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 SMART SM00089 2282 2376 1.1 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 SMART SM00089 2580 2674 7.4 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 SMART SM00089 2475 2575 0.3 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS10955 cc547f4d1247a4c0d9abebc4945a1c9d 2791 SMART SM00089 1942 2063 13.0 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS23105 aa00df89315bac259b49331c5758cc1e 131 Pfam PF04138 GtrA-like protein 10 123 1.3E-19 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 THSYN_RS06085 533c823f35d25a89dc6eaa1b67b1471e 376 SUPERFAMILY SSF159245 44 369 4.05E-114 T 29-03-2018 THSYN_RS06085 533c823f35d25a89dc6eaa1b67b1471e 376 Pfam PF17186 Lipocalin-like domain 241 369 8.1E-42 T 29-03-2018 THSYN_RS06085 533c823f35d25a89dc6eaa1b67b1471e 376 Pfam PF07143 CrtC N-terminal lipocalin domain 67 237 1.8E-53 T 29-03-2018 IPR010791 AttH domain THSYN_RS06085 533c823f35d25a89dc6eaa1b67b1471e 376 Gene3D G3DSA:2.40.370.10 55 240 9.8E-67 T 29-03-2018 IPR023374 AttH-like domain THSYN_RS06085 533c823f35d25a89dc6eaa1b67b1471e 376 Gene3D G3DSA:2.40.370.10 241 375 4.8E-48 T 29-03-2018 IPR023374 AttH-like domain THSYN_RS05330 7999a4841a53628fcf159166455303ad 163 SUPERFAMILY SSF53927 7 155 5.14E-48 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 THSYN_RS05330 7999a4841a53628fcf159166455303ad 163 Gene3D G3DSA:3.40.140.10 1 163 2.7E-43 T 29-03-2018 THSYN_RS05330 7999a4841a53628fcf159166455303ad 163 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 11 108 1.5E-23 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain THSYN_RS05330 7999a4841a53628fcf159166455303ad 163 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 60 97 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 THSYN_RS09590 236d56b0d2c7f824ae3b343948e9d081 537 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 167 338 2.1E-48 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09590 236d56b0d2c7f824ae3b343948e9d081 537 Pfam PF10531 SLBB domain 362 410 4.8E-7 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09590 236d56b0d2c7f824ae3b343948e9d081 537 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 449 532 4.9E-34 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09590 236d56b0d2c7f824ae3b343948e9d081 537 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 22 102 8.3E-8 T 29-03-2018 THSYN_RS09590 236d56b0d2c7f824ae3b343948e9d081 537 SUPERFAMILY SSF52833 23 115 1.12E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS09590 236d56b0d2c7f824ae3b343948e9d081 537 SUPERFAMILY SSF140490 445 534 1.96E-35 T 29-03-2018 THSYN_RS09590 236d56b0d2c7f824ae3b343948e9d081 537 Gene3D G3DSA:3.40.30.10 20 118 1.5E-15 T 29-03-2018 THSYN_RS09590 236d56b0d2c7f824ae3b343948e9d081 537 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 461 472 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09590 236d56b0d2c7f824ae3b343948e9d081 537 SUPERFAMILY SSF142984 360 443 3.66E-25 T 29-03-2018 THSYN_RS09590 236d56b0d2c7f824ae3b343948e9d081 537 SUPERFAMILY SSF142019 118 359 1.27E-90 T 29-03-2018 THSYN_RS09590 236d56b0d2c7f824ae3b343948e9d081 537 SMART SM00928 448 493 5.0E-22 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09450 2f322bdde6673f67ff6340260401db26 163 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 157 23.583 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 THSYN_RS09450 2f322bdde6673f67ff6340260401db26 163 SUPERFAMILY SSF75420 2 84 8.24E-24 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal THSYN_RS09450 2f322bdde6673f67ff6340260401db26 163 SUPERFAMILY SSF74942 85 156 1.83E-11 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal THSYN_RS09450 2f322bdde6673f67ff6340260401db26 163 Gene3D G3DSA:3.30.300.70 1 81 8.3E-26 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal THSYN_RS09450 2f322bdde6673f67ff6340260401db26 163 Pfam PF17384 RimP C-terminal SH3 domain 89 156 1.0E-11 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal THSYN_RS09450 2f322bdde6673f67ff6340260401db26 163 Gene3D G3DSA:2.30.30.180 89 154 2.2E-12 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal THSYN_RS09450 2f322bdde6673f67ff6340260401db26 163 Pfam PF02576 RimP N-terminal domain 12 84 1.1E-25 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal THSYN_RS11060 7129351ba0111689e2ed052558966353 82 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 4 68 4.1E-17 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS11060 7129351ba0111689e2ed052558966353 82 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 3 64 1.6E-19 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS11060 7129351ba0111689e2ed052558966353 82 SUPERFAMILY SSF47598 1 46 4.11E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS11060 7129351ba0111689e2ed052558966353 82 Gene3D G3DSA:1.10.1220.10 6 44 9.6E-9 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS29055 43f06c758c3d24cc0cf28ea3ca2e1e7d 410 Pfam PF00534 Glycosyl transferases group 1 243 369 7.3E-11 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS29055 43f06c758c3d24cc0cf28ea3ca2e1e7d 410 Pfam PF13579 Glycosyl transferase 4-like domain 6 204 1.4E-7 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS29055 43f06c758c3d24cc0cf28ea3ca2e1e7d 410 Gene3D G3DSA:3.40.50.2000 214 383 1.4E-24 T 29-03-2018 THSYN_RS29055 43f06c758c3d24cc0cf28ea3ca2e1e7d 410 SUPERFAMILY SSF53756 103 399 4.24E-35 T 29-03-2018 THSYN_RS29055 43f06c758c3d24cc0cf28ea3ca2e1e7d 410 SUPERFAMILY SSF53756 6 56 4.24E-35 T 29-03-2018 THSYN_RS29055 43f06c758c3d24cc0cf28ea3ca2e1e7d 410 Gene3D G3DSA:3.40.50.2000 6 213 0.0018 T 29-03-2018 THSYN_RS26200 a713b7ebb00a7f428f1003c40d8da6db 417 Gene3D G3DSA:3.40.50.1110 70 347 1.2E-7 T 29-03-2018 THSYN_RS30315 178f22cbe033ebfaffec6d929b7723ee 221 SUPERFAMILY SSF46894 120 218 1.08E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS30315 178f22cbe033ebfaffec6d929b7723ee 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 8.1E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS30315 178f22cbe033ebfaffec6d929b7723ee 221 SMART SM00862 146 217 2.8E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS30315 178f22cbe033ebfaffec6d929b7723ee 221 SUPERFAMILY SSF52172 1 118 1.57E-34 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS30315 178f22cbe033ebfaffec6d929b7723ee 221 Gene3D G3DSA:1.10.10.10 113 221 2.2E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS30315 178f22cbe033ebfaffec6d929b7723ee 221 SMART SM00448 1 112 1.6E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS30315 178f22cbe033ebfaffec6d929b7723ee 221 Pfam PF00072 Response regulator receiver domain 4 113 1.1E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS30315 178f22cbe033ebfaffec6d929b7723ee 221 Gene3D G3DSA:3.40.50.2300 1 112 2.4E-30 T 29-03-2018 THSYN_RS07755 14332397f2c9b150d1edcbf88ab3154c 243 Gene3D G3DSA:3.40.50.2300 1 122 1.0E-31 T 29-03-2018 THSYN_RS07755 14332397f2c9b150d1edcbf88ab3154c 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 225 8.5E-14 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS07755 14332397f2c9b150d1edcbf88ab3154c 243 Gene3D G3DSA:1.10.10.10 123 232 1.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07755 14332397f2c9b150d1edcbf88ab3154c 243 SMART SM00862 152 225 1.4E-14 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS07755 14332397f2c9b150d1edcbf88ab3154c 243 Pfam PF00072 Response regulator receiver domain 7 116 4.1E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS07755 14332397f2c9b150d1edcbf88ab3154c 243 SUPERFAMILY SSF52172 2 127 1.12E-33 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS07755 14332397f2c9b150d1edcbf88ab3154c 243 SUPERFAMILY SSF46894 132 226 2.61E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS07755 14332397f2c9b150d1edcbf88ab3154c 243 SMART SM00448 5 115 1.0E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS32540 633a3adf9cd72652a192a4afcdf78109 342 TIGRFAM TIGR02030 BchI-ChlI: magnesium chelatase ATPase subunit I 5 340 7.7E-156 T 29-03-2018 IPR011775 Magnesium chelatase, ATPase subunit I GO:0005524|GO:0015995|GO:0016851 KEGG: 00860+6.6.1.1|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS32540 633a3adf9cd72652a192a4afcdf78109 342 Gene3D G3DSA:1.10.8.80 252 340 1.8E-20 T 29-03-2018 THSYN_RS32540 633a3adf9cd72652a192a4afcdf78109 342 SMART SM00382 28 210 2.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS32540 633a3adf9cd72652a192a4afcdf78109 342 Gene3D G3DSA:3.40.50.300 3 207 3.0E-27 T 29-03-2018 THSYN_RS32540 633a3adf9cd72652a192a4afcdf78109 342 Pfam PF01078 Magnesium chelatase, subunit ChlI 117 187 1.4E-8 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain THSYN_RS32540 633a3adf9cd72652a192a4afcdf78109 342 SUPERFAMILY SSF52540 4 329 9.14E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02685 1fcbc0ecf152b4ab3ad85b8714085ff3 474 Pfam PF12710 haloacid dehalogenase-like hydrolase 11 118 4.7E-6 T 29-03-2018 THSYN_RS02685 1fcbc0ecf152b4ab3ad85b8714085ff3 474 Pfam PF01040 UbiA prenyltransferase family 206 440 2.5E-22 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 THSYN_RS02685 1fcbc0ecf152b4ab3ad85b8714085ff3 474 SUPERFAMILY SSF56784 7 174 1.36E-13 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS02685 1fcbc0ecf152b4ab3ad85b8714085ff3 474 Gene3D G3DSA:3.40.50.1000 4 258 6.7E-13 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS09030 722d84cf85b0c5f580f356f5aa8a66ae 446 Gene3D G3DSA:3.40.640.10 65 290 1.1E-35 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS09030 722d84cf85b0c5f580f356f5aa8a66ae 446 SUPERFAMILY SSF53383 50 393 6.45E-79 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS09030 722d84cf85b0c5f580f356f5aa8a66ae 446 Pfam PF00155 Aminotransferase class I and II 52 384 1.2E-39 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THSYN_RS09030 722d84cf85b0c5f580f356f5aa8a66ae 446 Gene3D G3DSA:3.90.1150.10 291 399 7.6E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 SUPERFAMILY SSF141868 491 737 8.5E-52 T 29-03-2018 IPR001633 EAL domain THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 Pfam PF00990 Diguanylate cyclase, GGDEF domain 312 470 1.4E-47 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 SUPERFAMILY SSF55785 192 299 9.42E-19 T 29-03-2018 IPR000014 PAS domain THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 Pfam PF13426 PAS domain 199 299 6.4E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 SMART SM00086 259 301 6.8E-5 T 29-03-2018 IPR001610 PAC motif THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 310 471 3.8E-45 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 SUPERFAMILY SSF55073 317 476 8.63E-50 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 SMART SM00091 67 133 8.1 T 29-03-2018 IPR000014 PAS domain THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 SMART SM00091 187 253 0.031 T 29-03-2018 IPR000014 PAS domain THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 191 305 4.3E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 Gene3D G3DSA:3.30.70.270 309 477 1.3E-60 T 29-03-2018 THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 SUPERFAMILY SSF55785 57 157 1.43E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 SMART SM00267 301 474 6.3E-64 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 Gene3D G3DSA:3.20.20.450 478 741 5.7E-58 T 29-03-2018 IPR001633 EAL domain THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 Gene3D G3DSA:3.30.450.20 180 308 1.3E-18 T 29-03-2018 THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 Gene3D G3DSA:3.30.450.20 54 179 1.1E-13 T 29-03-2018 THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 SMART SM00052 484 730 3.9E-53 T 29-03-2018 IPR001633 EAL domain THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 Pfam PF08448 PAS fold 73 151 1.1E-5 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS24965 7aff71e1a960d0dee40cfd01145ab508 777 Pfam PF00563 EAL domain 490 725 4.2E-44 T 29-03-2018 IPR001633 EAL domain THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 Pfam PF00271 Helicase conserved C-terminal domain 441 544 1.7E-17 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 Pfam PF02151 UvrB/uvrC motif 631 663 1.6E-9 T 29-03-2018 IPR001943 UVR domain GO:0005515 THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 Gene3D G3DSA:3.40.50.300 415 589 1.0E-30 T 29-03-2018 THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 Pfam PF12344 Ultra-violet resistance protein B 552 593 1.3E-20 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 Gene3D G3DSA:3.40.50.300 10 413 6.3E-34 T 29-03-2018 THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 5 663 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 SUPERFAMILY SSF46600 618 663 3.01E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 Gene3D G3DSA:4.10.860.10 609 669 3.0E-15 T 29-03-2018 IPR001943 UVR domain GO:0005515 THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 SMART SM00490 460 546 6.5E-21 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 SUPERFAMILY SSF52540 459 580 7.03E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 SUPERFAMILY SSF52540 37 82 7.03E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 SUPERFAMILY SSF52540 3 415 1.66E-134 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 SMART SM00487 9 426 2.3E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 Pfam PF04851 Type III restriction enzyme, res subunit 16 139 8.3E-10 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS26245 7a29345ae660a0f9246c945b3ccd3906 669 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 665 43.428 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 SUPERFAMILY SSF81653 350 457 6.28E-28 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 SMART SM00831 237 310 7.5E-29 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 Pfam PF00690 Cation transporter/ATPase, N-terminus 239 304 1.3E-15 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 560 566 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 447 578 4.5E-23 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 826 950 1.4E-33 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 Gene3D G3DSA:1.20.1110.10 772 1120 2.2E-87 T 29-03-2018 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 Gene3D G3DSA:3.40.1110.10 522 765 2.6E-43 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 Pfam PF00122 E1-E2 ATPase 349 538 7.5E-49 T 29-03-2018 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 SUPERFAMILY SSF81660 565 762 5.45E-51 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 Gene3D G3DSA:2.70.150.10 248 458 2.8E-40 T 29-03-2018 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 716 734 4.7E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 831 847 4.7E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 891 916 4.7E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 859 875 4.7E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 Pfam PF00702 haloacid dehalogenase-like hydrolase 555 873 5.5E-22 T 29-03-2018 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 Pfam PF04654 Protein of unknown function, DUF599 18 218 6.9E-47 T 29-03-2018 IPR006747 Protein of unknown function DUF599 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 SUPERFAMILY SSF56784 713 964 6.04E-61 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 SUPERFAMILY SSF56784 556 576 6.04E-61 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 Pfam PF00689 Cation transporting ATPase, C-terminus 944 1116 1.1E-44 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 SUPERFAMILY SSF81665 909 1121 3.66E-119 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 SUPERFAMILY SSF81665 458 552 3.66E-119 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 SUPERFAMILY SSF81665 238 348 3.66E-119 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 395 409 3.7E-40 T 29-03-2018 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 758 769 3.7E-40 T 29-03-2018 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 859 878 3.7E-40 T 29-03-2018 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 558 572 3.7E-40 T 29-03-2018 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 883 895 3.7E-40 T 29-03-2018 THSYN_RS15245 b50110cc8d6b796b57dec973aefb05c1 1156 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 780 790 3.7E-40 T 29-03-2018 THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 Pfam PF13191 AAA ATPase domain 277 464 2.1E-36 T 29-03-2018 THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 SMART SM00065 1320 1473 1.2E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 SMART SM00220 10 245 2.8E-8 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 Pfam PF00069 Protein kinase domain 87 237 1.5E-17 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 Gene3D G3DSA:3.40.50.300 277 484 3.6E-9 T 29-03-2018 THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1601 1687 5.9E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 Gene3D G3DSA:3.30.565.10 1557 1689 1.3E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 SUPERFAMILY SSF52540 402 517 5.87E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 SUPERFAMILY SSF52540 270 340 5.87E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 SUPERFAMILY SSF55874 1571 1684 6.02E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 Gene3D G3DSA:3.30.450.40 1305 1487 2.2E-22 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 Gene3D G3DSA:1.10.510.10 75 270 5.0E-31 T 29-03-2018 THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 SMART SM00387 1597 1688 8.3E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 SUPERFAMILY SSF55781 1306 1484 2.01E-19 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS05540 67bca811c918001202ffbded653210bc 1706 SUPERFAMILY SSF56112 82 248 1.62E-30 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 SUPERFAMILY SSF55073 548 714 1.1E-46 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 SUPERFAMILY SSF55785 402 525 6.81E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 SMART SM00086 364 406 5.9E-5 T 29-03-2018 IPR001610 PAC motif THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 SMART SM00086 110 151 0.17 T 29-03-2018 IPR001610 PAC motif THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 SMART SM00086 235 278 64.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 SMART SM00267 532 713 1.8E-59 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 Gene3D G3DSA:3.30.450.20 405 534 1.1E-19 T 29-03-2018 THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 Pfam PF00990 Diguanylate cyclase, GGDEF domain 543 709 5.9E-42 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 Gene3D G3DSA:3.30.450.20 279 402 2.1E-17 T 29-03-2018 THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 SMART SM00091 418 489 3.4 T 29-03-2018 IPR000014 PAS domain THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 SMART SM00091 22 88 3.5 T 29-03-2018 IPR000014 PAS domain THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 SMART SM00091 161 229 5.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 Pfam PF08448 PAS fold 445 532 1.2E-8 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 Pfam PF08448 PAS fold 176 279 6.1E-7 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 SUPERFAMILY SSF55785 275 404 2.97E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 Gene3D G3DSA:3.30.450.20 33 161 8.9E-13 T 29-03-2018 THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 SUPERFAMILY SSF55785 176 287 2.79E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 539 712 1.3E-37 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 Pfam PF08447 PAS fold 313 399 7.7E-9 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 Gene3D G3DSA:3.30.70.270 535 716 4.6E-56 T 29-03-2018 THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 Pfam PF00989 PAS fold 43 139 2.3E-8 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 415 538 1.6E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 Gene3D G3DSA:3.30.450.20 162 278 4.5E-15 T 29-03-2018 THSYN_RS21925 c2d8d1eb09b7d25fd81fa642001e413d 723 SUPERFAMILY SSF55785 43 155 3.14E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 Pfam PF00873 AcrB/AcrD/AcrF family 6 1023 2.6E-142 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 Gene3D G3DSA:1.20.1640.10 284 502 1.9E-30 T 29-03-2018 THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 Gene3D G3DSA:1.20.1640.10 809 1034 1.2E-41 T 29-03-2018 THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 SUPERFAMILY SSF82693 43 132 3.14E-21 T 29-03-2018 THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 3.0E-24 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 3.0E-24 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 3.0E-24 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 3.0E-24 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 3.0E-24 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 Gene3D G3DSA:3.30.70.1430 564 671 6.2E-8 T 29-03-2018 THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 SUPERFAMILY SSF82866 299 488 7.59E-35 T 29-03-2018 THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 SUPERFAMILY SSF82714 731 803 1.44E-9 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 Gene3D G3DSA:3.30.2090.10 176 263 9.2E-6 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 Gene3D G3DSA:3.30.2090.10 729 806 1.2E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 SUPERFAMILY SSF82866 805 1026 3.92E-44 T 29-03-2018 THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 SUPERFAMILY SSF82714 181 258 1.57E-5 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS20170 6fca16b688aa188e40496d698f5fc8c8 1046 Gene3D G3DSA:3.30.70.1430 43 141 1.3E-22 T 29-03-2018 THSYN_RS17925 ef45711aaf35322e001889e7d82d7edb 461 SUPERFAMILY SSF102114 7 448 2.75E-135 T 29-03-2018 THSYN_RS17925 ef45711aaf35322e001889e7d82d7edb 461 Pfam PF06969 HemN C-terminal domain 367 435 4.1E-7 T 29-03-2018 IPR010723 HemN, C-terminal THSYN_RS17925 ef45711aaf35322e001889e7d82d7edb 461 Pfam PF04055 Radical SAM superfamily 59 232 1.7E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS17925 ef45711aaf35322e001889e7d82d7edb 461 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 6 461 8.9E-190 T 29-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 THSYN_RS17925 ef45711aaf35322e001889e7d82d7edb 461 PIRSF PIRSF000167 5 457 4.2E-162 T 29-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 THSYN_RS17925 ef45711aaf35322e001889e7d82d7edb 461 SMART SM00729 53 276 7.3E-49 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS17925 ef45711aaf35322e001889e7d82d7edb 461 Gene3D G3DSA:3.20.20.70 25 356 9.4E-45 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS27790 5acdce3189f0d60f9e6027377f7783e6 320 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 67 78 3.7E-14 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THSYN_RS27790 5acdce3189f0d60f9e6027377f7783e6 320 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 110 124 3.7E-14 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THSYN_RS27790 5acdce3189f0d60f9e6027377f7783e6 320 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 41 49 3.7E-14 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THSYN_RS27790 5acdce3189f0d60f9e6027377f7783e6 320 SUPERFAMILY SSF53474 8 301 4.42E-66 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS27790 5acdce3189f0d60f9e6027377f7783e6 320 Pfam PF00561 alpha/beta hydrolase fold 42 301 5.4E-32 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS27790 5acdce3189f0d60f9e6027377f7783e6 320 Gene3D G3DSA:3.40.50.1820 2 318 5.9E-66 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS27790 5acdce3189f0d60f9e6027377f7783e6 320 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 13 315 2.3E-129 T 29-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 THSYN_RS27790 5acdce3189f0d60f9e6027377f7783e6 320 PIRSF PIRSF006431 3 319 1.7E-137 T 29-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 THSYN_RS27790 5acdce3189f0d60f9e6027377f7783e6 320 PRINTS PR00111 Alpha/beta hydrolase fold signature 64 79 6.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS27790 5acdce3189f0d60f9e6027377f7783e6 320 PRINTS PR00111 Alpha/beta hydrolase fold signature 124 137 6.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS27790 5acdce3189f0d60f9e6027377f7783e6 320 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 6.2E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS13270 7fc504f18614c060787c4191208d4848 246 Pfam PF12323 Helix-turn-helix domain 1 36 3.1E-11 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain THSYN_RS13270 7fc504f18614c060787c4191208d4848 246 Pfam PF07282 Putative transposase DNA-binding domain 148 213 4.2E-20 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal THSYN_RS13270 7fc504f18614c060787c4191208d4848 246 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 104 173 5.5E-10 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal THSYN_RS16730 feba1ee5ba5080673ed1abe7d716d88a 246 Gene3D G3DSA:2.60.120.10 132 240 1.2E-27 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS16730 feba1ee5ba5080673ed1abe7d716d88a 246 Gene3D G3DSA:2.60.120.10 12 131 1.6E-46 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS16730 feba1ee5ba5080673ed1abe7d716d88a 246 PIRSF PIRSF006232 1 239 1.8E-51 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 THSYN_RS16730 feba1ee5ba5080673ed1abe7d716d88a 246 Pfam PF02678 Pirin 9 119 5.5E-36 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 THSYN_RS16730 feba1ee5ba5080673ed1abe7d716d88a 246 SUPERFAMILY SSF51182 1 233 2.03E-72 T 29-03-2018 IPR011051 RmlC-like cupin domain THSYN_RS11780 6fad98770aabe0fe3eb99763d4b80974 197 Gene3D G3DSA:1.20.5.510 4 33 7.6E-16 T 29-03-2018 THSYN_RS11780 6fad98770aabe0fe3eb99763d4b80974 197 PRINTS PR00162 Rieske 2Fe-2S subunit signature 150 162 2.2E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THSYN_RS11780 6fad98770aabe0fe3eb99763d4b80974 197 PRINTS PR00162 Rieske 2Fe-2S subunit signature 119 130 2.2E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THSYN_RS11780 6fad98770aabe0fe3eb99763d4b80974 197 PRINTS PR00162 Rieske 2Fe-2S subunit signature 163 175 2.2E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THSYN_RS11780 6fad98770aabe0fe3eb99763d4b80974 197 Gene3D G3DSA:2.102.10.10 34 197 1.1E-40 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THSYN_RS11780 6fad98770aabe0fe3eb99763d4b80974 197 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 2 40 3.5E-15 T 29-03-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 THSYN_RS11780 6fad98770aabe0fe3eb99763d4b80974 197 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 8 191 1.6E-72 T 29-03-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 THSYN_RS11780 6fad98770aabe0fe3eb99763d4b80974 197 Pfam PF00355 Rieske [2Fe-2S] domain 114 175 8.1E-11 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THSYN_RS11780 6fad98770aabe0fe3eb99763d4b80974 197 SUPERFAMILY SSF50022 30 190 3.58E-42 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THSYN_RS26030 9b27b42f0ea456178c34b97d417e2b0c 302 Pfam PF12644 Protein of unknown function (DUF3782) 146 221 1.1E-22 T 29-03-2018 IPR024271 Protein of unknown function DUF3782 THSYN_RS26030 9b27b42f0ea456178c34b97d417e2b0c 302 SUPERFAMILY SSF57997 43 171 6.28E-5 T 29-03-2018 THSYN_RS26030 9b27b42f0ea456178c34b97d417e2b0c 302 Pfam PF07788 PD-(D/E)XK nuclease superfamily 222 291 2.8E-23 T 29-03-2018 IPR012431 PD-(D/E)XK nuclease THSYN_RS26030 9b27b42f0ea456178c34b97d417e2b0c 302 Gene3D G3DSA:1.20.5.340 64 141 6.5E-4 T 29-03-2018 THSYN_RS03035 eee8250e99e25998fbfe794ceb09ec37 455 Pfam PF00501 AMP-binding enzyme 142 295 3.2E-16 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THSYN_RS03035 eee8250e99e25998fbfe794ceb09ec37 455 Gene3D G3DSA:3.30.300.30 350 452 3.4E-15 T 29-03-2018 THSYN_RS03035 eee8250e99e25998fbfe794ceb09ec37 455 Gene3D G3DSA:3.40.50.980 150 304 1.1E-23 T 29-03-2018 THSYN_RS03035 eee8250e99e25998fbfe794ceb09ec37 455 SUPERFAMILY SSF56801 22 447 1.3E-50 T 29-03-2018 THSYN_RS03035 eee8250e99e25998fbfe794ceb09ec37 455 Gene3D G3DSA:3.40.50.980 21 149 4.9E-4 T 29-03-2018 THSYN_RS05080 e5c60af240c821eda8b4d9d14a4fe15e 285 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 13 275 1.4E-96 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 THSYN_RS05080 e5c60af240c821eda8b4d9d14a4fe15e 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 281 1.5E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS05080 e5c60af240c821eda8b4d9d14a4fe15e 285 SUPERFAMILY SSF161098 24 273 7.48E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS05080 e5c60af240c821eda8b4d9d14a4fe15e 285 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 16 278 1.5E-124 T 29-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 THSYN_RS05080 e5c60af240c821eda8b4d9d14a4fe15e 285 Gene3D G3DSA:1.10.3720.10 20 283 7.8E-39 T 29-03-2018 THSYN_RS02695 7e12a3cd385415635f719fc02a7000d5 246 Pfam PF00106 short chain dehydrogenase 5 193 2.9E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS02695 7e12a3cd385415635f719fc02a7000d5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 7.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS02695 7e12a3cd385415635f719fc02a7000d5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 7.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS02695 7e12a3cd385415635f719fc02a7000d5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 7.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS02695 7e12a3cd385415635f719fc02a7000d5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 7.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS02695 7e12a3cd385415635f719fc02a7000d5 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 7.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS02695 7e12a3cd385415635f719fc02a7000d5 246 Gene3D G3DSA:3.40.50.720 2 245 3.3E-37 T 29-03-2018 THSYN_RS02695 7e12a3cd385415635f719fc02a7000d5 246 SUPERFAMILY SSF51735 4 243 6.18E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS02695 7e12a3cd385415635f719fc02a7000d5 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THSYN_RS21540 a1243183db6fc919a9ca4cdc0b7f0187 506 SUPERFAMILY SSF53067 17 137 3.08E-33 T 29-03-2018 THSYN_RS21540 a1243183db6fc919a9ca4cdc0b7f0187 506 SUPERFAMILY SSF53067 142 316 1.76E-44 T 29-03-2018 THSYN_RS21540 a1243183db6fc919a9ca4cdc0b7f0187 506 Pfam PF02541 Ppx/GppA phosphatase family 30 314 5.6E-72 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 THSYN_RS21540 a1243183db6fc919a9ca4cdc0b7f0187 506 SUPERFAMILY SSF109604 318 504 6.28E-49 T 29-03-2018 THSYN_RS21540 a1243183db6fc919a9ca4cdc0b7f0187 506 PIRSF PIRSF001267 8 506 2.5E-182 T 29-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 THSYN_RS21540 a1243183db6fc919a9ca4cdc0b7f0187 506 Gene3D G3DSA:1.10.3210.10 313 455 0.0019 T 29-03-2018 THSYN_RS21540 a1243183db6fc919a9ca4cdc0b7f0187 506 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 17 311 9.3E-93 T 29-03-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 THSYN_RS21540 a1243183db6fc919a9ca4cdc0b7f0187 506 Gene3D G3DSA:3.30.420.40 8 129 1.1E-35 T 29-03-2018 THSYN_RS21540 a1243183db6fc919a9ca4cdc0b7f0187 506 Gene3D G3DSA:3.30.420.150 130 310 4.4E-36 T 29-03-2018 THSYN_RS06380 ed74ac51625d714bbaa89efdda222301 71 SMART SM00966 4 49 1.1E-4 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS06380 ed74ac51625d714bbaa89efdda222301 71 Gene3D G3DSA:2.10.260.10 2 46 1.0E-7 T 29-03-2018 THSYN_RS06380 ed74ac51625d714bbaa89efdda222301 71 SUPERFAMILY SSF89447 1 47 1.92E-8 T 29-03-2018 THSYN_RS06380 ed74ac51625d714bbaa89efdda222301 71 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 43 7.3E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1002 1016 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 454 468 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Gene3D G3DSA:2.130.10.10 551 689 7.0E-24 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Gene3D G3DSA:2.40.50.140 773 828 4.1E-10 T 29-03-2018 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Gene3D G3DSA:2.40.50.140 690 736 6.6E-8 T 29-03-2018 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 719 733 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Gene3D G3DSA:2.120.10.30 103 216 2.1E-19 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Gene3D G3DSA:2.130.10.10 849 955 2.5E-27 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SUPERFAMILY SSF50998 533 559 4.39E-67 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SUPERFAMILY SSF50998 606 644 4.39E-67 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SUPERFAMILY SSF50998 696 1070 4.39E-67 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1052 1066 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 867 881 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 957 971 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SUPERFAMILY SSF50978 240 285 2.56E-65 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SUPERFAMILY SSF50978 158 188 2.56E-65 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SUPERFAMILY SSF50978 338 551 2.56E-65 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Gene3D G3DSA:1.10.10.670 508 550 5.7E-7 T 29-03-2018 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Gene3D G3DSA:1.10.10.670 418 466 6.2E-16 T 29-03-2018 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Gene3D G3DSA:1.10.10.670 372 417 2.1E-10 T 29-03-2018 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Gene3D G3DSA:1.10.10.670 467 507 4.3E-14 T 29-03-2018 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SUPERFAMILY SSF50978 112 332 9.34E-39 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Gene3D G3DSA:2.40.10.120 737 772 3.9E-11 T 29-03-2018 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 PRINTS PR01547 Saccharomyces cerevisiae 175.8kDa hypothetical protein signature 1049 1067 3.3E-6 T 29-03-2018 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 PRINTS PR01547 Saccharomyces cerevisiae 175.8kDa hypothetical protein signature 44 65 3.3E-6 T 29-03-2018 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 287 326 0.059 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 977 1015 8.8E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 887 926 2.3E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 198 234 33.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 383 421 0.0012 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 648 685 0.2 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 1022 1065 8.0E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 337 376 1.4E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 932 970 1.3E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 735 774 2.0E-8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 427 467 1.4E-9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 146 185 7.7E-6 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 470 508 0.099 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 103 139 1.1 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 241 280 1.8E-7 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 599 638 0.23 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 840 880 0.046 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 512 550 1.7 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 777 820 4.1 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 SMART SM00320 693 732 3.4E-6 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Gene3D G3DSA:2.140.10.10 956 1091 2.2E-28 T 29-03-2018 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 267 281 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 892 926 7.9E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 696 732 0.0055 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 254 280 3.7E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 114 139 0.0084 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 351 376 3.4E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 740 774 5.2E-6 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 159 185 1.3E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 299 324 0.0028 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 855 880 0.17 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 1042 1065 4.6E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 435 467 4.0E-8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 803 820 0.062 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 941 969 0.0043 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Pfam PF00400 WD domain, G-beta repeat 389 421 0.18 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 PRINTS PR00320 G protein beta WD-40 repeat signature 267 281 2.4E-8 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 PRINTS PR00320 G protein beta WD-40 repeat signature 454 468 2.4E-8 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 PRINTS PR00320 G protein beta WD-40 repeat signature 761 775 2.4E-8 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat THSYN_RS25560 fa1218be2aa4a83b51c94a3fad90d1b3 1174 Gene3D G3DSA:2.130.10.10 217 371 2.9E-39 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS06010 2d460fb2c0fb0740cb2a45f061cd7127 516 SMART SM00917 372 503 9.7E-40 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS06010 2d460fb2c0fb0740cb2a45f061cd7127 516 Pfam PF00682 HMGL-like 7 275 2.7E-98 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 THSYN_RS06010 2d460fb2c0fb0740cb2a45f061cd7127 516 Gene3D G3DSA:3.20.20.70 1 333 6.8E-111 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS06010 2d460fb2c0fb0740cb2a45f061cd7127 516 SUPERFAMILY SSF51569 3 293 4.76E-100 T 29-03-2018 THSYN_RS06010 2d460fb2c0fb0740cb2a45f061cd7127 516 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 14 30 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS06010 2d460fb2c0fb0740cb2a45f061cd7127 516 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 201 214 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS06010 2d460fb2c0fb0740cb2a45f061cd7127 516 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 7 500 5.8E-217 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS06010 2d460fb2c0fb0740cb2a45f061cd7127 516 Pfam PF08502 LeuA allosteric (dimerisation) domain 373 503 2.0E-36 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS06010 2d460fb2c0fb0740cb2a45f061cd7127 516 SUPERFAMILY SSF110921 395 502 1.57E-24 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS06010 2d460fb2c0fb0740cb2a45f061cd7127 516 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 4 512 43.996 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS30255 f5518d062da5ab0329f75a0252a5d934 406 Pfam PF04233 Phage Mu protein F like protein 55 176 2.8E-16 T 29-03-2018 IPR006528 Phage head morphogenesis domain THSYN_RS32400 f75a2cf60504709a26e80abe4270b39a 76 Gene3D G3DSA:3.40.1620.10 1 38 4.6E-16 T 29-03-2018 THSYN_RS32400 f75a2cf60504709a26e80abe4270b39a 76 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 44 1.4E-9 T 29-03-2018 THSYN_RS32400 f75a2cf60504709a26e80abe4270b39a 76 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 41 2.4E-10 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS32400 f75a2cf60504709a26e80abe4270b39a 76 SUPERFAMILY SSF143120 1 43 1.44E-10 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS22135 633962827fdd0e4f2ae901511898e679 205 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 7 201 1.6E-104 T 29-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 THSYN_RS22135 633962827fdd0e4f2ae901511898e679 205 PIRSF PIRSF005624 2 203 1.9E-48 T 29-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 THSYN_RS22135 633962827fdd0e4f2ae901511898e679 205 Hamap MF_01389 Urease accessory protein UreG [ureG]. 5 203 48.665 T 29-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 THSYN_RS22135 633962827fdd0e4f2ae901511898e679 205 SUPERFAMILY SSF52540 4 198 4.73E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22135 633962827fdd0e4f2ae901511898e679 205 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 9 179 4.1E-40 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THSYN_RS22135 633962827fdd0e4f2ae901511898e679 205 Gene3D G3DSA:3.40.50.300 7 195 9.8E-19 T 29-03-2018 THSYN_RS09545 bdcb017c10ec9a11d02346bbd8deda15 304 Pfam PF03781 Sulfatase-modifying factor enzyme 1 42 265 1.2E-35 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS09545 bdcb017c10ec9a11d02346bbd8deda15 304 Gene3D G3DSA:3.90.1580.10 31 91 3.6E-5 T 29-03-2018 THSYN_RS09545 bdcb017c10ec9a11d02346bbd8deda15 304 Gene3D G3DSA:3.90.1580.10 92 275 2.1E-46 T 29-03-2018 THSYN_RS09545 bdcb017c10ec9a11d02346bbd8deda15 304 SUPERFAMILY SSF56436 41 265 1.62E-55 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS09145 84340ca98a1845eca269e2c58bed722e 397 Pfam PF00762 Ferrochelatase 50 367 7.8E-113 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 THSYN_RS09145 84340ca98a1845eca269e2c58bed722e 397 Gene3D G3DSA:3.40.50.1400 45 220 3.2E-48 T 29-03-2018 THSYN_RS09145 84340ca98a1845eca269e2c58bed722e 397 SUPERFAMILY SSF53800 48 372 7.59E-111 T 29-03-2018 THSYN_RS09145 84340ca98a1845eca269e2c58bed722e 397 ProSitePatterns PS00534 Ferrochelatase signature. 237 256 - T 29-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 THSYN_RS09145 84340ca98a1845eca269e2c58bed722e 397 Hamap MF_00323 Ferrochelatase [hemH]. 47 368 38.154 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 THSYN_RS09145 84340ca98a1845eca269e2c58bed722e 397 TIGRFAM TIGR00109 hemH: ferrochelatase 47 367 2.4E-95 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 THSYN_RS09145 84340ca98a1845eca269e2c58bed722e 397 Gene3D G3DSA:3.40.50.1400 221 347 9.5E-43 T 29-03-2018 THSYN_RS30950 99d78567204c2b7720dbce46f41c62a7 558 Gene3D G3DSA:1.10.10.10 2 129 8.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07835 99d78567204c2b7720dbce46f41c62a7 558 Gene3D G3DSA:1.10.10.10 2 129 8.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS14470 99d78567204c2b7720dbce46f41c62a7 558 Gene3D G3DSA:1.10.10.10 2 129 8.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS10115 99d78567204c2b7720dbce46f41c62a7 558 Gene3D G3DSA:1.10.10.10 2 129 8.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS16250 99d78567204c2b7720dbce46f41c62a7 558 Gene3D G3DSA:1.10.10.10 2 129 8.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS16790 99d78567204c2b7720dbce46f41c62a7 558 Gene3D G3DSA:1.10.10.10 2 129 8.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS16565 99d78567204c2b7720dbce46f41c62a7 558 Gene3D G3DSA:1.10.10.10 2 129 8.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07515 99d78567204c2b7720dbce46f41c62a7 558 Gene3D G3DSA:1.10.10.10 2 129 8.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SMART SM00387 1261 1384 4.3E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SMART SM00091 852 918 6.9E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SMART SM00091 724 792 71.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SMART SM00091 471 536 2.8E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SMART SM00091 599 666 1.8E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 Gene3D G3DSA:3.30.450.20 703 841 1.3E-22 T 29-03-2018 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 Gene3D G3DSA:3.30.450.20 842 993 1.5E-33 T 29-03-2018 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 Pfam PF08448 PAS fold 858 968 1.2E-10 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SUPERFAMILY SSF55785 837 965 1.54E-26 T 29-03-2018 IPR000014 PAS domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 467 601 1.1E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 596 719 1.4E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 771 846 1.2E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 848 972 3.6E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 Gene3D G3DSA:3.30.565.10 1228 1389 9.8E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 Pfam PF13426 PAS domain 610 711 9.1E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1265 1383 2.0E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 Gene3D G3DSA:3.30.450.20 453 596 2.7E-21 T 29-03-2018 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1331 1341 1.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1344 1362 1.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1368 1381 1.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1313 1327 1.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 Gene3D G3DSA:1.10.287.130 1138 1217 1.3E-4 T 29-03-2018 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SUPERFAMILY SSF55874 1212 1382 1.57E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SUPERFAMILY SSF55785 593 710 2.23E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SMART SM00086 798 840 3.3E-6 T 29-03-2018 IPR001610 PAC motif THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SMART SM00086 925 967 1.3E-4 T 29-03-2018 IPR001610 PAC motif THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SMART SM00086 672 712 24.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 Gene3D G3DSA:3.30.450.20 597 702 3.0E-18 T 29-03-2018 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 Gene3D G3DSA:3.40.50.2300 1419 1544 2.5E-24 T 29-03-2018 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 Pfam PF13188 PAS domain 472 514 1.1E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SUPERFAMILY SSF52172 1422 1537 7.68E-25 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SMART SM00448 1424 1535 5.6E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 Pfam PF08447 PAS fold 747 834 1.1E-14 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SUPERFAMILY SSF55785 464 592 3.49E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 Pfam PF00072 Response regulator receiver domain 1426 1534 3.4E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS21505 fa5bb9a9c662b6cae115b55d734dacef 1552 SUPERFAMILY SSF55785 733 842 1.68E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS15740 c03164183bc264721bf86299fd5f4c11 114 Pfam PF01230 HIT domain 11 107 1.3E-28 T 29-03-2018 IPR001310 Histidine triad (HIT) protein THSYN_RS15740 c03164183bc264721bf86299fd5f4c11 114 PRINTS PR00332 Histidine triad family signature 5 21 1.1E-19 T 29-03-2018 IPR001310 Histidine triad (HIT) protein THSYN_RS15740 c03164183bc264721bf86299fd5f4c11 114 PRINTS PR00332 Histidine triad family signature 26 44 1.1E-19 T 29-03-2018 IPR001310 Histidine triad (HIT) protein THSYN_RS15740 c03164183bc264721bf86299fd5f4c11 114 PRINTS PR00332 Histidine triad family signature 94 104 1.1E-19 T 29-03-2018 IPR001310 Histidine triad (HIT) protein THSYN_RS15740 c03164183bc264721bf86299fd5f4c11 114 SUPERFAMILY SSF54197 2 113 5.81E-37 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 THSYN_RS15740 c03164183bc264721bf86299fd5f4c11 114 ProSitePatterns PS00892 HIT domain signature. 87 105 - T 29-03-2018 IPR019808 Histidine triad, conserved site THSYN_RS15740 c03164183bc264721bf86299fd5f4c11 114 Gene3D G3DSA:3.30.428.10 1 109 9.3E-33 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 Gene3D G3DSA:1.25.40.10 264 420 1.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 Gene3D G3DSA:1.10.10.10 467 531 2.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 Gene3D G3DSA:1.10.10.10 593 667 3.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 SUPERFAMILY SSF48452 519 643 9.62E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 SUPERFAMILY SSF48452 355 474 5.42E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 Pfam PF13424 Tetratricopeptide repeat 525 597 2.5E-12 T 29-03-2018 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 Pfam PF13424 Tetratricopeptide repeat 400 473 4.0E-13 T 29-03-2018 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 SUPERFAMILY SSF48452 435 558 5.82E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 Gene3D G3DSA:3.30.70.100 443 466 7.3E-4 T 29-03-2018 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 SMART SM00028 526 559 45.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 SMART SM00028 568 601 59.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 SMART SM00028 442 475 41.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 SMART SM00028 400 433 20.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 SMART SM00028 610 643 160.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 SMART SM00028 484 517 17.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 Pfam PF13374 Tetratricopeptide repeat 609 649 0.0079 T 29-03-2018 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 Pfam PF13374 Tetratricopeptide repeat 483 524 1.6E-8 T 29-03-2018 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 Gene3D G3DSA:1.20.1250.10 532 592 2.2E-12 T 29-03-2018 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 Gene3D G3DSA:1.20.5.1140 421 442 7.1E-5 T 29-03-2018 THSYN_RS29875 5cfef5b3ff0b10dbcd807da777806f18 684 SUPERFAMILY SSF52540 26 201 3.04E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08695 2b8f7a799019bc43d0cdae6f55b3213b 157 PRINTS PR00601 Bacterioferritin signature 3 22 3.9E-48 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08695 2b8f7a799019bc43d0cdae6f55b3213b 157 PRINTS PR00601 Bacterioferritin signature 107 127 3.9E-48 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08695 2b8f7a799019bc43d0cdae6f55b3213b 157 PRINTS PR00601 Bacterioferritin signature 23 43 3.9E-48 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08695 2b8f7a799019bc43d0cdae6f55b3213b 157 PRINTS PR00601 Bacterioferritin signature 65 85 3.9E-48 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08695 2b8f7a799019bc43d0cdae6f55b3213b 157 PRINTS PR00601 Bacterioferritin signature 129 150 3.9E-48 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08695 2b8f7a799019bc43d0cdae6f55b3213b 157 PRINTS PR00601 Bacterioferritin signature 86 106 3.9E-48 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08695 2b8f7a799019bc43d0cdae6f55b3213b 157 PRINTS PR00601 Bacterioferritin signature 44 64 3.9E-48 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08695 2b8f7a799019bc43d0cdae6f55b3213b 157 PIRSF PIRSF002560 1 157 2.7E-62 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08695 2b8f7a799019bc43d0cdae6f55b3213b 157 SUPERFAMILY SSF47240 1 156 3.37E-45 T 29-03-2018 IPR009078 Ferritin-like superfamily THSYN_RS08695 2b8f7a799019bc43d0cdae6f55b3213b 157 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 2.8E-50 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08695 2b8f7a799019bc43d0cdae6f55b3213b 157 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08695 2b8f7a799019bc43d0cdae6f55b3213b 157 Gene3D G3DSA:1.20.1260.10 2 151 9.1E-35 T 29-03-2018 IPR012347 Ferritin-related THSYN_RS08695 2b8f7a799019bc43d0cdae6f55b3213b 157 Pfam PF00210 Ferritin-like domain 8 145 4.6E-36 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 THSYN_RS31920 c8e6bfc15602cd4bf86fb08f340e067b 197 Pfam PF01400 Astacin (Peptidase family M12A) 38 110 1.2E-6 T 29-03-2018 IPR001506 Peptidase M12A GO:0004222|GO:0006508 THSYN_RS31920 c8e6bfc15602cd4bf86fb08f340e067b 197 SUPERFAMILY SSF55486 11 193 5.34E-20 T 29-03-2018 THSYN_RS31920 c8e6bfc15602cd4bf86fb08f340e067b 197 Gene3D G3DSA:3.40.390.10 1 197 2.4E-21 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 THSYN_RS20295 3b9cfa6a7e7ea8104ae956131dddbb0a 291 Gene3D G3DSA:3.90.1010.10 1 158 3.7E-54 T 29-03-2018 THSYN_RS20295 3b9cfa6a7e7ea8104ae956131dddbb0a 291 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 227 285 3.0E-20 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 THSYN_RS20295 3b9cfa6a7e7ea8104ae956131dddbb0a 291 TIGRFAM TIGR02000 NifU_proper: Fe-S cluster assembly protein NifU 1 284 1.5E-139 T 29-03-2018 IPR010238 NIF system FeS cluster assembly, NifU GO:0005506|GO:0016226|GO:0051536 THSYN_RS20295 3b9cfa6a7e7ea8104ae956131dddbb0a 291 Pfam PF04324 BFD-like [2Fe-2S] binding domain 135 184 3.5E-16 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain THSYN_RS20295 3b9cfa6a7e7ea8104ae956131dddbb0a 291 PIRSF PIRSF000375 1 285 6.6E-126 T 29-03-2018 IPR016217 Nitrogen fixation, NifU THSYN_RS20295 3b9cfa6a7e7ea8104ae956131dddbb0a 291 Gene3D G3DSA:3.30.300.130 213 289 1.4E-19 T 29-03-2018 IPR034904 Fe-S cluster assembly domain THSYN_RS20295 3b9cfa6a7e7ea8104ae956131dddbb0a 291 Pfam PF01592 NifU-like N terminal domain 4 124 2.4E-47 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 THSYN_RS20295 3b9cfa6a7e7ea8104ae956131dddbb0a 291 SUPERFAMILY SSF82649 2 131 1.75E-40 T 29-03-2018 THSYN_RS20295 3b9cfa6a7e7ea8104ae956131dddbb0a 291 Pfam PF01106 NifU-like domain 218 281 9.9E-20 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 THSYN_RS20295 3b9cfa6a7e7ea8104ae956131dddbb0a 291 SUPERFAMILY SSF117916 209 284 1.07E-18 T 29-03-2018 IPR034904 Fe-S cluster assembly domain THSYN_RS27230 6542fc53195a2f0e2e2bb33cdca4975e 296 Gene3D G3DSA:2.160.20.50 67 145 6.6E-9 T 29-03-2018 THSYN_RS27230 6542fc53195a2f0e2e2bb33cdca4975e 296 Pfam PF01391 Collagen triple helix repeat (20 copies) 84 137 1.1E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat THSYN_RS27230 6542fc53195a2f0e2e2bb33cdca4975e 296 Pfam PF07603 Protein of unknown function (DUF1566) 156 293 5.0E-13 T 29-03-2018 IPR011460 Protein of unknown function DUF1566 THSYN_RS03005 4c3b4c891b71ceab8e4a00f716a41473 447 Gene3D G3DSA:3.30.9.10 179 342 1.1E-22 T 29-03-2018 THSYN_RS03005 4c3b4c891b71ceab8e4a00f716a41473 447 Gene3D G3DSA:3.50.50.60 11 178 4.5E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03005 4c3b4c891b71ceab8e4a00f716a41473 447 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 9.1E-7 T 29-03-2018 THSYN_RS03005 4c3b4c891b71ceab8e4a00f716a41473 447 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 166 181 9.1E-7 T 29-03-2018 THSYN_RS03005 4c3b4c891b71ceab8e4a00f716a41473 447 Pfam PF01494 FAD binding domain 15 340 1.9E-23 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 THSYN_RS03005 4c3b4c891b71ceab8e4a00f716a41473 447 SUPERFAMILY SSF51905 283 387 1.56E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03005 4c3b4c891b71ceab8e4a00f716a41473 447 SUPERFAMILY SSF51905 15 187 1.56E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS25745 8b966883154bef438158cae8715725c8 172 Pfam PF00149 Calcineurin-like phosphoesterase 19 113 6.9E-8 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS25745 8b966883154bef438158cae8715725c8 172 SUPERFAMILY SSF56300 18 149 3.19E-15 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS25745 8b966883154bef438158cae8715725c8 172 Gene3D G3DSA:3.60.21.10 5 171 2.8E-13 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS32485 b158084daa7d56348f98d59656c06881 308 Pfam PF12697 Alpha/beta hydrolase family 88 281 4.6E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS32485 b158084daa7d56348f98d59656c06881 308 Gene3D G3DSA:3.40.50.1820 52 308 1.0E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS32485 b158084daa7d56348f98d59656c06881 308 SUPERFAMILY SSF53474 13 305 2.14E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS18625 2c2acad5de15d6516bcf0775a1cc1c05 447 Gene3D G3DSA:3.30.70.270 273 442 2.0E-55 T 29-03-2018 THSYN_RS18625 2c2acad5de15d6516bcf0775a1cc1c05 447 SUPERFAMILY SSF52172 8 144 9.68E-38 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS18625 2c2acad5de15d6516bcf0775a1cc1c05 447 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 279 440 1.9E-40 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS18625 2c2acad5de15d6516bcf0775a1cc1c05 447 Pfam PF08448 PAS fold 147 263 4.9E-8 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS18625 2c2acad5de15d6516bcf0775a1cc1c05 447 SUPERFAMILY SSF55073 285 439 5.26E-46 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS18625 2c2acad5de15d6516bcf0775a1cc1c05 447 Pfam PF00072 Response regulator receiver domain 13 123 2.9E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18625 2c2acad5de15d6516bcf0775a1cc1c05 447 Gene3D G3DSA:3.30.450.20 135 272 7.7E-14 T 29-03-2018 THSYN_RS18625 2c2acad5de15d6516bcf0775a1cc1c05 447 SMART SM00267 266 441 2.5E-60 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS18625 2c2acad5de15d6516bcf0775a1cc1c05 447 Pfam PF00990 Diguanylate cyclase, GGDEF domain 280 435 1.6E-44 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS18625 2c2acad5de15d6516bcf0775a1cc1c05 447 SMART SM00448 10 123 9.6E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18625 2c2acad5de15d6516bcf0775a1cc1c05 447 Gene3D G3DSA:3.40.50.2300 4 134 5.9E-38 T 29-03-2018 THSYN_RS18625 2c2acad5de15d6516bcf0775a1cc1c05 447 SUPERFAMILY SSF55785 128 260 3.35E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS07715 2faaf7e050e69ac1309d04403d39c662 391 Gene3D G3DSA:1.10.260.40 14 133 5.3E-7 T 29-03-2018 THSYN_RS07715 2faaf7e050e69ac1309d04403d39c662 391 Pfam PF06114 IrrE N-terminal-like domain 178 305 4.1E-21 T 29-03-2018 IPR010359 IrrE N-terminal-like domain THSYN_RS07715 2faaf7e050e69ac1309d04403d39c662 391 SUPERFAMILY SSF47413 15 64 1.04E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS19110 1c1705508ccbaf18c4be6c0a7db81427 433 Pfam PF03781 Sulfatase-modifying factor enzyme 1 190 409 3.8E-42 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS19110 1c1705508ccbaf18c4be6c0a7db81427 433 SUPERFAMILY SSF56436 188 409 7.77E-56 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS19110 1c1705508ccbaf18c4be6c0a7db81427 433 Gene3D G3DSA:3.90.1580.10 235 425 3.4E-46 T 29-03-2018 THSYN_RS19110 1c1705508ccbaf18c4be6c0a7db81427 433 Gene3D G3DSA:3.90.1580.10 181 234 2.9E-8 T 29-03-2018 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 335 410 9.9E-35 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 18 331 1.0E-118 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Gene3D G3DSA:1.10.150.20 445 515 9.4E-29 T 29-03-2018 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 420 447 1.2E-8 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Hamap MF_01588 DNA ligase [ligA]. 16 760 52.402 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 SMART SM00532 17 461 4.9E-245 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 SUPERFAMILY SSF47781 417 580 1.33E-50 T 29-03-2018 IPR010994 RuvA domain 2-like THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Gene3D G3DSA:1.10.287.610 9 80 1.1E-26 T 29-03-2018 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 SUPERFAMILY SSF56091 17 331 1.54E-111 T 29-03-2018 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 SMART SM00278 493 512 2.4 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 SMART SM00278 459 478 7.5 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 SMART SM00278 525 544 110.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 25 756 2.0E-238 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 SUPERFAMILY SSF52113 688 760 9.72E-18 T 29-03-2018 IPR001357 BRCT domain THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Gene3D G3DSA:3.40.50.10190 661 763 3.8E-21 T 29-03-2018 IPR001357 BRCT domain THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Gene3D G3DSA:3.30.1490.70 253 334 5.8E-20 T 29-03-2018 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 SMART SM00292 687 763 1.3E-11 T 29-03-2018 IPR001357 BRCT domain THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 688 760 5.6E-10 T 29-03-2018 IPR001357 BRCT domain THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Gene3D G3DSA:2.40.50.140 335 403 2.9E-34 T 29-03-2018 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 SUPERFAMILY SSF50249 331 412 2.57E-27 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Pfam PF14520 Helix-hairpin-helix domain 459 513 4.9E-7 T 29-03-2018 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Gene3D G3DSA:1.10.150.20 516 581 2.7E-18 T 29-03-2018 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Pfam PF12826 Helix-hairpin-helix motif 523 580 1.2E-12 T 29-03-2018 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Gene3D G3DSA:3.30.470.30 133 252 4.5E-50 T 29-03-2018 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 Gene3D G3DSA:1.10.150.20 590 660 1.4E-12 T 29-03-2018 THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 344 359 - T 29-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 SUPERFAMILY SSF47781 580 672 1.05E-11 T 29-03-2018 IPR010994 RuvA domain 2-like THSYN_RS23420 1d22c330d28d9f10f9474769e74e8db7 763 PIRSF PIRSF001604 12 763 1.1E-230 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 THSYN_RS24680 a3936041fcfe50f0c94bc21ece5c2ec9 404 SUPERFAMILY SSF103473 11 393 3.4E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS24680 a3936041fcfe50f0c94bc21ece5c2ec9 404 Gene3D G3DSA:1.20.1250.20 202 395 4.1E-18 T 29-03-2018 THSYN_RS24680 a3936041fcfe50f0c94bc21ece5c2ec9 404 Pfam PF07690 Major Facilitator Superfamily 21 240 1.1E-14 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THSYN_RS24680 a3936041fcfe50f0c94bc21ece5c2ec9 404 Gene3D G3DSA:1.20.1250.20 1 193 1.5E-21 T 29-03-2018 THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 SUPERFAMILY SSF47413 6 51 6.14E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 SMART SM00530 5 64 3.7E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 Pfam PF13020 Domain of unknown function (DUF3883) 1066 1155 1.9E-13 T 29-03-2018 IPR024975 Domain of unknown function DUF3883 THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 Gene3D G3DSA:1.10.10.60 4 28 1.5E-10 T 29-03-2018 THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 SUPERFAMILY SSF52540 101 325 3.1E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 Gene3D G3DSA:3.40.50.300 513 683 2.8E-27 T 29-03-2018 THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 Pfam PF01381 Helix-turn-helix 7 47 3.5E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 SUPERFAMILY SSF52540 513 681 1.34E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 SUPERFAMILY SSF52540 237 317 1.34E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 Pfam PF00271 Helicase conserved C-terminal domain 523 641 4.2E-17 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 SMART SM00487 113 325 2.4E-11 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 SMART SM00490 552 641 1.5E-16 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 Pfam PF00176 SNF2 family N-terminal domain 138 323 4.2E-10 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 Gene3D G3DSA:1.10.10.10 29 129 0.0011 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS17715 5a69a299f55be15ab77a7a40ab01a1fd 1192 Gene3D G3DSA:3.40.50.10810 130 354 5.6E-22 T 29-03-2018 THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 131 276 4.6E-50 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 3 438 2.9E-169 T 29-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 Pfam PF13375 RnfC Barrel sandwich hybrid domain 5 106 4.0E-30 T 29-03-2018 IPR026902 RnfC Barrel sandwich hybrid domain THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 408 419 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 Gene3D G3DSA:3.40.50.720 134 317 5.4E-4 T 29-03-2018 THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 Gene3D G3DSA:3.30.70.20 351 378 0.2 T 29-03-2018 THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 SUPERFAMILY SSF142019 87 296 6.93E-57 T 29-03-2018 THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 494 157.569 T 29-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 Gene3D G3DSA:3.30.70.20 379 416 1.3E-7 T 29-03-2018 THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 SUPERFAMILY SSF46548 330 436 5.36E-18 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 Pfam PF12800 4Fe-4S binding domain 407 419 0.33 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 Pfam PF12800 4Fe-4S binding domain 369 380 0.0058 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 Pfam PF10531 SLBB domain 289 337 4.8E-11 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS26955 95d813b7c2d0d69788c3421e507763fb 494 Gene3D G3DSA:3.30.70.20 417 489 0.0038 T 29-03-2018 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 SMART SM00388 172 237 2.7E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 SMART SM00448 431 544 2.5E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 Pfam PF08447 PAS fold 45 127 3.6E-7 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 SUPERFAMILY SSF52172 429 550 1.57E-36 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 284 398 8.5E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 Gene3D G3DSA:3.30.450.20 31 75 9.5E-5 T 29-03-2018 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 SUPERFAMILY SSF47384 157 238 2.94E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 SMART SM00387 284 400 6.3E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 Pfam PF00512 His Kinase A (phospho-acceptor) domain 172 237 2.8E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 378 1.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 339 1.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 353 1.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 397 1.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 SUPERFAMILY SSF55874 226 395 1.7E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 89 141 2.5E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 Gene3D G3DSA:3.30.565.10 241 406 3.9E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 Gene3D G3DSA:3.30.450.20 1 26 0.019 T 29-03-2018 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 Gene3D G3DSA:3.40.50.2300 417 555 1.3E-39 T 29-03-2018 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 SMART SM00086 93 134 1.6E-4 T 29-03-2018 IPR001610 PAC motif THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 SUPERFAMILY SSF55785 5 132 9.57E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 Pfam PF00072 Response regulator receiver domain 434 544 5.6E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 Gene3D G3DSA:1.10.287.130 176 233 4.8E-20 T 29-03-2018 THSYN_RS27365 4c2a92908bd47c513266f5b959d24f47 649 Gene3D G3DSA:3.30.450.20 76 175 8.7E-15 T 29-03-2018 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 5.7E-41 T 29-03-2018 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 5.7E-41 T 29-03-2018 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 5.7E-41 T 29-03-2018 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 5.7E-41 T 29-03-2018 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 5.7E-41 T 29-03-2018 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 Gene3D G3DSA:3.50.50.60 1 146 3.5E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 Gene3D G3DSA:3.40.50.720 147 263 5.8E-24 T 29-03-2018 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 301 5.4E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 Gene3D G3DSA:3.50.50.60 264 321 5.0E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 2.8E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 2.8E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 2.8E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 2.8E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 2.8E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 2.8E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 2.8E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 2.8E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 2.8E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 SUPERFAMILY SSF51905 1 313 1.05E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 THSYN_RS26165 dd7260d819926e6a30574a6ae4f73a7d 321 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 9 313 5.5E-120 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 THSYN_RS29205 498ba636d9a65dca019cd11d1924a46e 216 SUPERFAMILY SSF53335 16 214 1.3E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS29205 498ba636d9a65dca019cd11d1924a46e 216 Gene3D G3DSA:3.40.50.150 12 216 8.4E-25 T 29-03-2018 THSYN_RS29205 498ba636d9a65dca019cd11d1924a46e 216 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 37 213 3.3E-48 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THSYN_RS29205 498ba636d9a65dca019cd11d1924a46e 216 PIRSF PIRSF003078 13 216 4.9E-55 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THSYN_RS29205 498ba636d9a65dca019cd11d1924a46e 216 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 24 212 27.462 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THSYN_RS29205 498ba636d9a65dca019cd11d1924a46e 216 Pfam PF02527 rRNA small subunit methyltransferase G 31 210 2.5E-49 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 Gene3D G3DSA:3.30.230.10 218 389 1.1E-60 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 Pfam PF00204 DNA gyrase B 218 387 1.9E-55 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 171 9.8E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 Gene3D G3DSA:3.30.565.10 15 217 2.3E-72 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 SUPERFAMILY SSF54211 218 389 4.74E-57 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 3 803 98.763 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 ProSitePatterns PS00177 DNA topoisomerase II signature. 419 427 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 Pfam PF01751 Toprim domain 416 528 8.7E-18 T 29-03-2018 IPR006171 TOPRIM domain THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 731 792 2.3E-30 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 Gene3D G3DSA:3.40.50.670 397 800 3.5E-107 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR01159 DNA gyrase subunit B signature 217 239 1.7E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR01159 DNA gyrase subunit B signature 467 476 1.7E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR01159 DNA gyrase subunit B signature 309 325 1.7E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR01159 DNA gyrase subunit B signature 178 193 1.7E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR01159 DNA gyrase subunit B signature 193 206 1.7E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR01159 DNA gyrase subunit B signature 357 371 1.7E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR01159 DNA gyrase subunit B signature 756 768 1.7E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR01159 DNA gyrase subunit B signature 3 13 1.7E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR01159 DNA gyrase subunit B signature 371 391 1.7E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR01159 DNA gyrase subunit B signature 772 788 1.7E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 SUPERFAMILY SSF55874 3 215 1.96E-72 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 SMART SM00387 29 173 2.7E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 SMART SM00433 33 796 1.0E-260 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR00418 DNA topoisomerase II family signature 522 534 1.1E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR00418 DNA topoisomerase II family signature 735 751 1.1E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR00418 DNA topoisomerase II family signature 484 500 1.1E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR00418 DNA topoisomerase II family signature 68 81 1.1E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR00418 DNA topoisomerase II family signature 417 431 1.1E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR00418 DNA topoisomerase II family signature 265 278 1.1E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR00418 DNA topoisomerase II family signature 502 519 1.1E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR00418 DNA topoisomerase II family signature 33 48 1.1E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 PRINTS PR00418 DNA topoisomerase II family signature 111 125 1.1E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 SUPERFAMILY SSF56719 729 797 3.14E-87 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 SUPERFAMILY SSF56719 391 557 3.14E-87 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THSYN_RS00020 44ad121d3109c6da015071de3cd31647 803 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 3 803 6.1E-302 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS22465 fd99cee4ded46d996afd0a380b62fd74 289 Pfam PF03411 Penicillin-insensitive murein endopeptidase 51 286 4.0E-87 T 29-03-2018 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 THSYN_RS22465 fd99cee4ded46d996afd0a380b62fd74 289 PIRSF PIRSF018455 8 289 2.3E-88 T 29-03-2018 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 THSYN_RS22465 fd99cee4ded46d996afd0a380b62fd74 289 Gene3D G3DSA:3.30.1380.10 34 289 3.3E-84 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS22465 fd99cee4ded46d996afd0a380b62fd74 289 SUPERFAMILY SSF55166 36 288 1.41E-81 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS13335 30d157e0890f94c4ff3b7d91fd2007b8 709 Pfam PF01061 ABC-2 type transporter 454 657 2.3E-21 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 THSYN_RS13335 30d157e0890f94c4ff3b7d91fd2007b8 709 SUPERFAMILY SSF52540 147 388 6.55E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13335 30d157e0890f94c4ff3b7d91fd2007b8 709 SMART SM00240 66 116 7.2E-13 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THSYN_RS13335 30d157e0890f94c4ff3b7d91fd2007b8 709 ProSitePatterns PS00211 ABC transporters family signature. 296 310 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS13335 30d157e0890f94c4ff3b7d91fd2007b8 709 SMART SM00382 183 370 9.6E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS13335 30d157e0890f94c4ff3b7d91fd2007b8 709 Gene3D G3DSA:3.40.50.300 150 448 9.3E-62 T 29-03-2018 THSYN_RS13335 30d157e0890f94c4ff3b7d91fd2007b8 709 Gene3D G3DSA:2.60.200.20 59 141 5.8E-19 T 29-03-2018 THSYN_RS13335 30d157e0890f94c4ff3b7d91fd2007b8 709 Gene3D G3DSA:2.60.200.20 8 58 0.0037 T 29-03-2018 THSYN_RS13335 30d157e0890f94c4ff3b7d91fd2007b8 709 SUPERFAMILY SSF49879 64 156 1.53E-23 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 THSYN_RS13335 30d157e0890f94c4ff3b7d91fd2007b8 709 Pfam PF00498 FHA domain 67 130 4.8E-15 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THSYN_RS13335 30d157e0890f94c4ff3b7d91fd2007b8 709 Pfam PF00005 ABC transporter 174 324 2.2E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS29590 4a8e5a06226c0e908e35237b82ccc100 208 Pfam PF13508 Acetyltransferase (GNAT) domain 46 147 2.5E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS29590 4a8e5a06226c0e908e35237b82ccc100 208 Gene3D G3DSA:3.40.630.30 25 190 4.3E-19 T 29-03-2018 THSYN_RS29590 4a8e5a06226c0e908e35237b82ccc100 208 SUPERFAMILY SSF55729 21 153 8.11E-16 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS23935 fbb73e2b7625b06ea8c200ea13f5621d 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23935 fbb73e2b7625b06ea8c200ea13f5621d 156 PIRSF PIRSF002122 2 156 6.3E-61 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 THSYN_RS23935 fbb73e2b7625b06ea8c200ea13f5621d 156 Gene3D G3DSA:1.10.455.10 6 156 5.6E-64 T 29-03-2018 IPR023798 Ribosomal protein S7 domain THSYN_RS23935 fbb73e2b7625b06ea8c200ea13f5621d 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 6.4E-69 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 THSYN_RS23935 fbb73e2b7625b06ea8c200ea13f5621d 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.1E-67 T 29-03-2018 IPR023798 Ribosomal protein S7 domain THSYN_RS23935 fbb73e2b7625b06ea8c200ea13f5621d 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 36.221 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 THSYN_RS23935 fbb73e2b7625b06ea8c200ea13f5621d 156 SUPERFAMILY SSF47973 6 149 3.14E-62 T 29-03-2018 IPR023798 Ribosomal protein S7 domain THSYN_RS20645 ee78f40aa17d207813c01f25abe7b208 196 Pfam PF05175 Methyltransferase small domain 25 190 2.5E-35 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 THSYN_RS20645 ee78f40aa17d207813c01f25abe7b208 196 Gene3D G3DSA:3.40.50.150 10 195 5.1E-33 T 29-03-2018 THSYN_RS20645 ee78f40aa17d207813c01f25abe7b208 196 SUPERFAMILY SSF53335 16 181 8.82E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS26005 6eaed3370aab075cf6cb3e1e8da209d2 415 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 208 414 1.1E-66 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 THSYN_RS26005 6eaed3370aab075cf6cb3e1e8da209d2 415 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 2.4E-22 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 PRINTS PR01900 YidC translocation/secretion protein signature 509 533 5.2E-24 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 PRINTS PR01900 YidC translocation/secretion protein signature 361 377 5.2E-24 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 PRINTS PR01900 YidC translocation/secretion protein signature 490 505 5.2E-24 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 375 554 4.2E-71 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 556 23.993 T 29-03-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 PRINTS PR00701 60kDa inner membrane protein signature 437 460 9.1E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 PRINTS PR00701 60kDa inner membrane protein signature 87 108 9.1E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 PRINTS PR00701 60kDa inner membrane protein signature 180 200 9.1E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 PRINTS PR00701 60kDa inner membrane protein signature 520 543 9.1E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 PRINTS PR00701 60kDa inner membrane protein signature 346 366 9.1E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 PRINTS PR00701 60kDa inner membrane protein signature 2 23 9.1E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 PRINTS PR00701 60kDa inner membrane protein signature 484 506 9.1E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 PRINTS PR00701 60kDa inner membrane protein signature 273 288 9.1E-72 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 374 3.0E-98 T 29-03-2018 IPR028053 Membrane insertase YidC, N-terminal THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 Pfam PF02096 60Kd inner membrane protein 376 553 2.6E-60 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THSYN_RS29280 1821911ece85f7e9852eb61a74f7986a 565 Pfam PF14849 YidC periplasmic domain 82 365 2.1E-79 T 29-03-2018 IPR028053 Membrane insertase YidC, N-terminal THSYN_RS19765 747932f655556209b374b12252c99b86 501 Gene3D G3DSA:3.30.830.10 64 288 6.5E-45 T 29-03-2018 THSYN_RS19765 747932f655556209b374b12252c99b86 501 SUPERFAMILY SSF63411 305 483 4.0E-40 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THSYN_RS19765 747932f655556209b374b12252c99b86 501 Pfam PF05193 Peptidase M16 inactive domain 239 415 1.8E-29 T 29-03-2018 IPR007863 Peptidase M16, C-terminal THSYN_RS19765 747932f655556209b374b12252c99b86 501 Gene3D G3DSA:3.30.830.10 303 494 3.8E-30 T 29-03-2018 THSYN_RS19765 747932f655556209b374b12252c99b86 501 SUPERFAMILY SSF63411 69 294 5.17E-45 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THSYN_RS19765 747932f655556209b374b12252c99b86 501 Pfam PF00675 Insulinase (Peptidase family M16) 84 231 1.5E-15 T 29-03-2018 IPR011765 Peptidase M16, N-terminal THSYN_RS27305 1584ed9785765ee2e15dba41f5255c1f 175 Gene3D G3DSA:2.30.30.240 106 175 5.5E-18 T 29-03-2018 THSYN_RS27305 1584ed9785765ee2e15dba41f5255c1f 175 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 16 174 3.3E-44 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 THSYN_RS27305 1584ed9785765ee2e15dba41f5255c1f 175 Gene3D G3DSA:2.40.30.60 14 100 1.5E-21 T 29-03-2018 IPR002676 RimM protein GO:0006364 THSYN_RS27305 1584ed9785765ee2e15dba41f5255c1f 175 Pfam PF01782 RimM N-terminal domain 18 96 8.7E-23 T 29-03-2018 IPR002676 RimM protein GO:0006364 THSYN_RS27305 1584ed9785765ee2e15dba41f5255c1f 175 Pfam PF05239 PRC-barrel domain 104 169 1.2E-4 T 29-03-2018 IPR027275 PRC-barrel domain THSYN_RS27305 1584ed9785765ee2e15dba41f5255c1f 175 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 15 175 22.382 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 THSYN_RS27305 1584ed9785765ee2e15dba41f5255c1f 175 SUPERFAMILY SSF50346 106 175 8.63E-17 T 29-03-2018 IPR011033 PRC-barrel-like THSYN_RS27305 1584ed9785765ee2e15dba41f5255c1f 175 SUPERFAMILY SSF50447 15 100 4.59E-20 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS14695 0538a8e0fbf96279b2c771b541253b62 91 PIRSF PIRSF028784 1 91 5.0E-26 T 29-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 THSYN_RS14695 0538a8e0fbf96279b2c771b541253b62 91 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 33 84 1.2E-20 T 29-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 THSYN_RS19665 d917ef5b8dca1d44a2cd38217449bbfd 264 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 206 0.0027 T 29-03-2018 THSYN_RS19665 d917ef5b8dca1d44a2cd38217449bbfd 264 Pfam PF00106 short chain dehydrogenase 8 214 9.8E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS19665 d917ef5b8dca1d44a2cd38217449bbfd 264 Gene3D G3DSA:3.40.50.720 1 263 2.0E-53 T 29-03-2018 THSYN_RS19665 d917ef5b8dca1d44a2cd38217449bbfd 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 6.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS19665 d917ef5b8dca1d44a2cd38217449bbfd 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 6.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS19665 d917ef5b8dca1d44a2cd38217449bbfd 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 6.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS19665 d917ef5b8dca1d44a2cd38217449bbfd 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 6.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS19665 d917ef5b8dca1d44a2cd38217449bbfd 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS19665 d917ef5b8dca1d44a2cd38217449bbfd 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS19665 d917ef5b8dca1d44a2cd38217449bbfd 264 SUPERFAMILY SSF51735 2 260 1.86E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS08460 99ac9ba10fd59d8122613e6c9ab13273 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 8.8E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS08460 99ac9ba10fd59d8122613e6c9ab13273 229 Gene3D G3DSA:3.40.50.2300 1 124 4.7E-32 T 29-03-2018 THSYN_RS08460 99ac9ba10fd59d8122613e6c9ab13273 229 Pfam PF00072 Response regulator receiver domain 8 117 1.4E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08460 99ac9ba10fd59d8122613e6c9ab13273 229 SUPERFAMILY SSF52172 5 184 1.4E-36 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS08460 99ac9ba10fd59d8122613e6c9ab13273 229 SMART SM00448 6 116 5.8E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08460 99ac9ba10fd59d8122613e6c9ab13273 229 Gene3D G3DSA:1.10.10.10 125 229 6.4E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS08460 99ac9ba10fd59d8122613e6c9ab13273 229 SMART SM00862 151 227 1.7E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS01515 b8ce80de90f00b0e8c286dbe1b294196 287 PIRSF PIRSF005917 1 279 1.3E-93 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS01515 b8ce80de90f00b0e8c286dbe1b294196 287 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 8 208 1.1E-28 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS01515 b8ce80de90f00b0e8c286dbe1b294196 287 Gene3D G3DSA:3.30.950.10 116 231 4.3E-35 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS01515 b8ce80de90f00b0e8c286dbe1b294196 287 Gene3D G3DSA:3.40.1010.10 5 115 7.9E-39 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS01515 b8ce80de90f00b0e8c286dbe1b294196 287 SUPERFAMILY SSF53790 6 226 2.22E-75 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS01515 b8ce80de90f00b0e8c286dbe1b294196 287 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 7 276 1.1E-80 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS01515 b8ce80de90f00b0e8c286dbe1b294196 287 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 7 228 35.66 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS06785 4aab1a443f22bcb6d90962e16df78ea8 363 Gene3D G3DSA:1.20.1170.10 193 351 1.5E-5 T 29-03-2018 THSYN_RS07400 7b97aa35978f9026b517a2ae143ecb32 361 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 18 351 2.2E-147 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 THSYN_RS07400 7b97aa35978f9026b517a2ae143ecb32 361 Pfam PF13484 4Fe-4S double cluster binding domain 197 261 1.1E-19 T 29-03-2018 THSYN_RS07400 7b97aa35978f9026b517a2ae143ecb32 361 Gene3D G3DSA:3.30.70.20 205 277 2.1E-10 T 29-03-2018 THSYN_RS07400 7b97aa35978f9026b517a2ae143ecb32 361 Gene3D G3DSA:3.30.70.20 97 204 2.1E-5 T 29-03-2018 THSYN_RS07400 7b97aa35978f9026b517a2ae143ecb32 361 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 198 209 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS07400 7b97aa35978f9026b517a2ae143ecb32 361 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 11 320 49.517 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 THSYN_RS07400 7b97aa35978f9026b517a2ae143ecb32 361 Pfam PF08331 Domain of unknown function (DUF1730) 66 145 3.3E-23 T 29-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 THSYN_RS07400 7b97aa35978f9026b517a2ae143ecb32 361 SUPERFAMILY SSF54862 175 325 4.6E-19 T 29-03-2018 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 480 498 2.3E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 518 540 2.3E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 551 561 2.3E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 2.3E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 2.3E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 2.3E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 2.3E-51 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 SUPERFAMILY SSF52374 5 226 1.91E-139 T 29-03-2018 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 SUPERFAMILY SSF52374 416 663 1.91E-139 T 29-03-2018 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 Gene3D G3DSA:3.90.740.10 228 402 5.2E-48 T 29-03-2018 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 403 9.0E-69 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 SUPERFAMILY SSF50677 226 415 4.32E-51 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 Pfam PF08264 Anticodon-binding domain of tRNA 701 817 1.5E-15 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 Gene3D G3DSA:3.40.50.620 403 642 5.5E-56 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 Gene3D G3DSA:3.40.50.620 1 227 7.6E-77 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 SUPERFAMILY SSF47323 657 873 3.36E-32 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 613 651 6.5E-6 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 171 1.0E-25 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 418 566 2.1E-7 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 6 873 0.0 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 872 22.374 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS28255 f4de574d42187da92e532c82eeb7bb69 873 Gene3D G3DSA:1.10.730.10 643 792 1.6E-30 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS03300 f914ad1b06a035aca146c1a867261264 190 Pfam PF01420 Type I restriction modification DNA specificity domain 6 134 1.1E-6 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS03300 f914ad1b06a035aca146c1a867261264 190 Gene3D G3DSA:3.90.220.20 2 133 3.8E-13 T 29-03-2018 THSYN_RS03300 f914ad1b06a035aca146c1a867261264 190 SUPERFAMILY SSF116734 4 134 4.74E-22 T 29-03-2018 THSYN_RS04570 29f2ed613c79fc19fbbb4d44999b9eb6 208 SMART SM00702 21 205 2.1E-24 T 29-03-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 THSYN_RS04570 29f2ed613c79fc19fbbb4d44999b9eb6 208 Gene3D G3DSA:2.60.120.620 11 208 2.5E-35 T 29-03-2018 THSYN_RS04570 29f2ed613c79fc19fbbb4d44999b9eb6 208 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 113 204 1.7E-18 T 29-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 THSYN_RS00340 20fd89b627b2e28de465f77967c57528 659 SUPERFAMILY SSF56300 516 565 1.13E-8 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS00340 20fd89b627b2e28de465f77967c57528 659 SUPERFAMILY SSF56300 380 420 1.13E-8 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS00340 20fd89b627b2e28de465f77967c57528 659 SUPERFAMILY SSF56300 465 481 1.13E-8 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS00340 20fd89b627b2e28de465f77967c57528 659 SUPERFAMILY SSF56300 185 267 1.13E-8 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS00340 20fd89b627b2e28de465f77967c57528 659 Gene3D G3DSA:3.60.21.10 12 607 1.7E-41 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS00340 20fd89b627b2e28de465f77967c57528 659 Hamap MF_01854 Fructose-1,6-bisphosphatase class 3 [fbp]. 9 651 36.085 T 29-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 THSYN_RS00340 20fd89b627b2e28de465f77967c57528 659 Pfam PF06874 Firmicute fructose-1,6-bisphosphatase 11 649 1.2E-277 T 29-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 THSYN_RS00340 20fd89b627b2e28de465f77967c57528 659 PIRSF PIRSF000906 5 652 3.5E-257 T 29-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 THSYN_RS06390 b391017f4c50a3f06c4a6c1d3e816110 1022 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 316 322 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS06390 b391017f4c50a3f06c4a6c1d3e816110 1022 SUPERFAMILY SSF53335 12 486 7.37E-66 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS06390 b391017f4c50a3f06c4a6c1d3e816110 1022 SUPERFAMILY SSF116734 837 1008 2.45E-27 T 29-03-2018 THSYN_RS06390 b391017f4c50a3f06c4a6c1d3e816110 1022 Pfam PF01420 Type I restriction modification DNA specificity domain 837 994 8.6E-14 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS06390 b391017f4c50a3f06c4a6c1d3e816110 1022 Pfam PF02384 N-6 DNA Methylase 157 475 2.9E-32 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS06390 b391017f4c50a3f06c4a6c1d3e816110 1022 Gene3D G3DSA:3.90.220.20 644 818 6.4E-14 T 29-03-2018 THSYN_RS06390 b391017f4c50a3f06c4a6c1d3e816110 1022 Gene3D G3DSA:3.90.220.20 820 1002 1.7E-26 T 29-03-2018 THSYN_RS06390 b391017f4c50a3f06c4a6c1d3e816110 1022 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 202 216 2.5E-11 T 29-03-2018 THSYN_RS06390 b391017f4c50a3f06c4a6c1d3e816110 1022 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 343 367 2.5E-11 T 29-03-2018 THSYN_RS06390 b391017f4c50a3f06c4a6c1d3e816110 1022 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 178 194 2.5E-11 T 29-03-2018 THSYN_RS06390 b391017f4c50a3f06c4a6c1d3e816110 1022 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 313 325 2.5E-11 T 29-03-2018 THSYN_RS06390 b391017f4c50a3f06c4a6c1d3e816110 1022 SUPERFAMILY SSF116734 661 816 1.64E-12 T 29-03-2018 THSYN_RS06390 b391017f4c50a3f06c4a6c1d3e816110 1022 Gene3D G3DSA:3.40.50.150 177 566 9.3E-35 T 29-03-2018 THSYN_RS20125 86acfcf78109c32de3aa7d5e62e0044e 607 SUPERFAMILY SSF51569 2 299 1.59E-89 T 29-03-2018 THSYN_RS20125 86acfcf78109c32de3aa7d5e62e0044e 607 Gene3D G3DSA:1.10.10.60 398 443 3.5E-12 T 29-03-2018 THSYN_RS20125 86acfcf78109c32de3aa7d5e62e0044e 607 Gene3D G3DSA:3.20.20.70 1 283 3.3E-76 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS20125 86acfcf78109c32de3aa7d5e62e0044e 607 Gene3D G3DSA:2.40.50.100 531 605 7.7E-19 T 29-03-2018 THSYN_RS20125 86acfcf78109c32de3aa7d5e62e0044e 607 Pfam PF02436 Conserved carboxylase domain 291 478 1.3E-55 T 29-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 THSYN_RS20125 86acfcf78109c32de3aa7d5e62e0044e 607 SUPERFAMILY SSF89000 296 448 1.02E-48 T 29-03-2018 THSYN_RS20125 86acfcf78109c32de3aa7d5e62e0044e 607 Pfam PF00682 HMGL-like 4 266 1.6E-48 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 THSYN_RS20125 86acfcf78109c32de3aa7d5e62e0044e 607 SUPERFAMILY SSF51230 529 604 2.22E-20 T 29-03-2018 IPR011053 Single hybrid motif THSYN_RS20125 86acfcf78109c32de3aa7d5e62e0044e 607 Pfam PF00364 Biotin-requiring enzyme 538 604 1.0E-15 T 29-03-2018 IPR000089 Biotin/lipoyl attachment THSYN_RS20125 86acfcf78109c32de3aa7d5e62e0044e 607 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 6 601 2.7E-256 T 29-03-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 THSYN_RS12520 1c4319a809134b2c68472235d99b053a 523 SUPERFAMILY SSF52540 240 474 1.68E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12520 1c4319a809134b2c68472235d99b053a 523 Gene3D G3DSA:3.40.50.300 189 408 1.3E-29 T 29-03-2018 THSYN_RS12520 1c4319a809134b2c68472235d99b053a 523 Gene3D G3DSA:1.10.8.60 409 475 2.5E-11 T 29-03-2018 THSYN_RS12520 1c4319a809134b2c68472235d99b053a 523 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 275 400 6.4E-25 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS12520 1c4319a809134b2c68472235d99b053a 523 SMART SM00382 270 403 1.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS15190 c966014ae8bb1bb57c734e07eed3ff64 247 Gene3D G3DSA:1.10.10.10 152 238 8.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS15190 c966014ae8bb1bb57c734e07eed3ff64 247 SMART SM00419 163 211 5.2E-7 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS15190 c966014ae8bb1bb57c734e07eed3ff64 247 SUPERFAMILY SSF46785 149 223 6.69E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS15190 c966014ae8bb1bb57c734e07eed3ff64 247 Pfam PF13545 Crp-like helix-turn-helix domain 152 216 3.3E-14 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS15190 c966014ae8bb1bb57c734e07eed3ff64 247 SMART SM00100 13 134 3.4E-5 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS15190 c966014ae8bb1bb57c734e07eed3ff64 247 Gene3D G3DSA:2.60.120.10 8 151 3.7E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS15190 c966014ae8bb1bb57c734e07eed3ff64 247 SUPERFAMILY SSF51206 10 134 4.71E-12 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like THSYN_RS00490 7439d0c3dd450b4538f72aa694b3712e 95 Pfam PF00582 Universal stress protein family 14 95 3.7E-21 T 29-03-2018 IPR006016 UspA GO:0006950 THSYN_RS00490 7439d0c3dd450b4538f72aa694b3712e 95 SUPERFAMILY SSF52402 14 95 2.34E-24 T 29-03-2018 THSYN_RS00490 7439d0c3dd450b4538f72aa694b3712e 95 Gene3D G3DSA:3.40.50.620 3 95 1.1E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS00490 7439d0c3dd450b4538f72aa694b3712e 95 PRINTS PR01438 Universal stress protein signature 73 95 7.4E-10 T 29-03-2018 IPR006015 Universal stress protein A THSYN_RS00490 7439d0c3dd450b4538f72aa694b3712e 95 PRINTS PR01438 Universal stress protein signature 55 67 7.4E-10 T 29-03-2018 IPR006015 Universal stress protein A THSYN_RS00430 d07ac8358a4458740f94deda3a256f65 237 Gene3D G3DSA:3.90.1580.10 51 100 0.024 T 29-03-2018 THSYN_RS00430 d07ac8358a4458740f94deda3a256f65 237 Gene3D G3DSA:3.90.1580.10 101 237 2.9E-15 T 29-03-2018 THSYN_RS00430 d07ac8358a4458740f94deda3a256f65 237 SUPERFAMILY SSF56436 71 231 1.51E-27 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS00430 d07ac8358a4458740f94deda3a256f65 237 Pfam PF03781 Sulfatase-modifying factor enzyme 1 72 184 3.7E-14 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS04180 feeba1f5dded14d27ffb0fd694704d5e 206 Gene3D G3DSA:2.40.160.20 18 206 1.3E-17 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THSYN_RS04180 feeba1f5dded14d27ffb0fd694704d5e 206 Pfam PF13505 Outer membrane protein beta-barrel domain 19 180 2.7E-16 T 29-03-2018 IPR027385 Outer membrane protein beta-barrel THSYN_RS04180 feeba1f5dded14d27ffb0fd694704d5e 206 SUPERFAMILY SSF56925 28 206 4.97E-14 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THSYN_RS14400 dde92eb6cd735b27ef4f67888a10f035 92 Pfam PF11103 Protein of unknown function (DUF2887) 3 62 1.7E-8 T 29-03-2018 IPR022573 Protein of unknown function DUF2887 THSYN_RS06365 3de180595c876dbc729479cb19033298 392 SMART SM00382 99 224 0.002 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS06365 3de180595c876dbc729479cb19033298 392 Gene3D G3DSA:3.40.50.300 83 224 3.1E-7 T 29-03-2018 THSYN_RS06365 3de180595c876dbc729479cb19033298 392 Pfam PF13173 AAA domain 100 231 3.9E-29 T 29-03-2018 THSYN_RS06365 3de180595c876dbc729479cb19033298 392 SUPERFAMILY SSF52540 94 288 3.38E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 Gene3D G3DSA:3.40.50.300 185 218 1.0E-4 T 29-03-2018 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 Gene3D G3DSA:3.40.50.300 546 780 4.2E-55 T 29-03-2018 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 7 771 8.4E-174 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 SMART SM00306 216 312 8.0E-13 T 29-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 525 546 4.3E-8 T 29-03-2018 IPR030934 Intein C-terminal splicing region THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 Gene3D G3DSA:2.170.16.10 477 545 6.9E-18 T 29-03-2018 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 Gene3D G3DSA:2.170.16.10 219 395 5.5E-34 T 29-03-2018 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 Gene3D G3DSA:1.10.860.10 1 149 4.8E-46 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 Pfam PF00772 DnaB-like helicase N terminal domain 7 108 3.4E-32 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 SMART SM00305 506 551 4.1E-11 T 29-03-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 SUPERFAMILY SSF48024 5 116 1.57E-35 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 SUPERFAMILY SSF51294 217 337 3.73E-44 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 SUPERFAMILY SSF51294 481 545 3.73E-44 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 Pfam PF14890 Intein splicing domain 265 545 3.6E-26 T 29-03-2018 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 Pfam PF14528 LAGLIDADG-like domain 403 483 2.5E-11 T 29-03-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 Gene3D G3DSA:3.10.28.10 396 476 2.3E-11 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 SUPERFAMILY SSF55608 388 500 5.61E-10 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 SUPERFAMILY SSF52540 546 583 3.45E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 SUPERFAMILY SSF52540 610 762 3.45E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 218 292 1.8E-7 T 29-03-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 PRINTS PR00379 Intein signature 279 292 1.2E-23 T 29-03-2018 IPR006142 Intein GO:0016539 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 PRINTS PR00379 Intein signature 540 549 1.2E-23 T 29-03-2018 IPR006142 Intein GO:0016539 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 PRINTS PR00379 Intein signature 326 338 1.2E-23 T 29-03-2018 IPR006142 Intein GO:0016539 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 PRINTS PR00379 Intein signature 522 539 1.2E-23 T 29-03-2018 IPR006142 Intein GO:0016539 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 PRINTS PR00379 Intein signature 402 414 1.2E-23 T 29-03-2018 IPR006142 Intein GO:0016539 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 PRINTS PR00379 Intein signature 433 448 1.2E-23 T 29-03-2018 IPR006142 Intein GO:0016539 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 SUPERFAMILY SSF52540 177 218 4.73E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 Pfam PF03796 DnaB-like helicase C terminal domain 543 769 3.5E-96 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 THSYN_RS23020 b916419d0acca70430c63a18affd046b 780 Pfam PF03796 DnaB-like helicase C terminal domain 186 219 6.2E-11 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 THSYN_RS05100 cbcc678e2af40f973c9a044191daffbf 262 Gene3D G3DSA:1.10.12.10 220 262 6.8E-15 T 29-03-2018 IPR014748 Crontonase, C-terminal THSYN_RS05100 cbcc678e2af40f973c9a044191daffbf 262 SUPERFAMILY SSF52096 7 261 8.24E-83 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS05100 cbcc678e2af40f973c9a044191daffbf 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 260 8.1E-60 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THSYN_RS05100 cbcc678e2af40f973c9a044191daffbf 262 Gene3D G3DSA:3.90.226.10 7 219 5.7E-68 T 29-03-2018 THSYN_RS19265 2de62f09642ae96f84bc29ec33ab4e45 129 SUPERFAMILY SSF53146 1 123 2.09E-32 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THSYN_RS19265 2de62f09642ae96f84bc29ec33ab4e45 129 Gene3D G3DSA:3.30.420.130 1 128 1.9E-28 T 29-03-2018 THSYN_RS19265 2de62f09642ae96f84bc29ec33ab4e45 129 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 104 9.2E-21 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THSYN_RS01710 ec6d2bbf8a7b91e864603a198eca8926 348 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 11 345 3.9E-112 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 THSYN_RS01710 ec6d2bbf8a7b91e864603a198eca8926 348 Gene3D G3DSA:3.20.20.70 8 348 1.1E-83 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS01710 ec6d2bbf8a7b91e864603a198eca8926 348 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 9 345 44.864 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 THSYN_RS01710 ec6d2bbf8a7b91e864603a198eca8926 348 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 301 321 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 THSYN_RS01710 ec6d2bbf8a7b91e864603a198eca8926 348 SUPERFAMILY SSF51395 11 345 1.16E-91 T 29-03-2018 THSYN_RS01710 ec6d2bbf8a7b91e864603a198eca8926 348 Pfam PF01180 Dihydroorotate dehydrogenase 56 346 1.9E-78 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 THSYN_RS01710 ec6d2bbf8a7b91e864603a198eca8926 348 PIRSF PIRSF000164 23 347 4.4E-93 T 29-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 THSYN_RS01710 ec6d2bbf8a7b91e864603a198eca8926 348 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 90 109 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 THSYN_RS22095 f71377016ee10960d46c08ad82aae387 557 SUPERFAMILY SSF52200 2 117 6.28E-16 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS22095 f71377016ee10960d46c08ad82aae387 557 PRINTS PR00364 Disease resistance protein signature 179 194 8.2E-10 T 29-03-2018 THSYN_RS22095 f71377016ee10960d46c08ad82aae387 557 PRINTS PR00364 Disease resistance protein signature 255 269 8.2E-10 T 29-03-2018 THSYN_RS22095 f71377016ee10960d46c08ad82aae387 557 PRINTS PR00364 Disease resistance protein signature 335 349 8.2E-10 T 29-03-2018 THSYN_RS22095 f71377016ee10960d46c08ad82aae387 557 Gene3D G3DSA:3.40.50.300 139 297 5.7E-13 T 29-03-2018 THSYN_RS22095 f71377016ee10960d46c08ad82aae387 557 Pfam PF00931 NB-ARC domain 175 366 2.8E-7 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 THSYN_RS22095 f71377016ee10960d46c08ad82aae387 557 Pfam PF13676 TIR domain 6 102 1.9E-16 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS22095 f71377016ee10960d46c08ad82aae387 557 SUPERFAMILY SSF52540 146 366 9.35E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22095 f71377016ee10960d46c08ad82aae387 557 Gene3D G3DSA:3.40.50.10140 2 130 1.4E-18 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS18885 60d05b03dfcfe75420568379ea39e6d9 208 ProSitePatterns PS00018 EF-hand calcium-binding domain. 42 54 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS18885 60d05b03dfcfe75420568379ea39e6d9 208 ProSitePatterns PS00018 EF-hand calcium-binding domain. 182 194 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS18885 60d05b03dfcfe75420568379ea39e6d9 208 Gene3D G3DSA:1.10.1330.10 52 89 2.0E-9 T 29-03-2018 THSYN_RS18885 60d05b03dfcfe75420568379ea39e6d9 208 Gene3D G3DSA:1.10.238.10 90 145 4.1E-6 T 29-03-2018 THSYN_RS18885 60d05b03dfcfe75420568379ea39e6d9 208 Pfam PF13202 EF hand 175 195 3.6E-8 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS18885 60d05b03dfcfe75420568379ea39e6d9 208 Pfam PF13202 EF hand 80 100 9.8E-4 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS18885 60d05b03dfcfe75420568379ea39e6d9 208 Pfam PF13202 EF hand 38 57 5.8E-4 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS18885 60d05b03dfcfe75420568379ea39e6d9 208 Pfam PF13202 EF hand 135 152 0.071 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS18885 60d05b03dfcfe75420568379ea39e6d9 208 ProSitePatterns PS00018 EF-hand calcium-binding domain. 85 97 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS18885 60d05b03dfcfe75420568379ea39e6d9 208 Gene3D G3DSA:1.10.238.10 23 51 5.3E-4 T 29-03-2018 THSYN_RS18885 60d05b03dfcfe75420568379ea39e6d9 208 SUPERFAMILY SSF47473 38 198 2.89E-14 T 29-03-2018 IPR011992 EF-hand domain pair THSYN_RS18885 60d05b03dfcfe75420568379ea39e6d9 208 Gene3D G3DSA:1.10.238.10 184 207 6.8E-4 T 29-03-2018 THSYN_RS18885 60d05b03dfcfe75420568379ea39e6d9 208 Gene3D G3DSA:1.10.238.10 146 183 3.3E-7 T 29-03-2018 THSYN_RS01980 1d2de79042585aaa24ce1285dec7be5a 302 Gene3D G3DSA:1.20.5.50 233 295 0.15 T 29-03-2018 THSYN_RS01980 1d2de79042585aaa24ce1285dec7be5a 302 SUPERFAMILY SSF55785 114 234 5.23E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS01980 1d2de79042585aaa24ce1285dec7be5a 302 SUPERFAMILY SSF57997 42 135 2.48E-6 T 29-03-2018 THSYN_RS01980 1d2de79042585aaa24ce1285dec7be5a 302 Gene3D G3DSA:3.30.450.20 126 232 9.2E-17 T 29-03-2018 THSYN_RS01980 1d2de79042585aaa24ce1285dec7be5a 302 Gene3D G3DSA:3.40.50.150 18 125 1.9E-11 T 29-03-2018 THSYN_RS01980 1d2de79042585aaa24ce1285dec7be5a 302 Pfam PF13596 PAS domain 129 233 2.6E-29 T 29-03-2018 THSYN_RS14330 61899fc8065aa729d58ea5e253cd6944 582 Pfam PF02374 Anion-transporting ATPase 327 467 8.4E-31 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 THSYN_RS14330 61899fc8065aa729d58ea5e253cd6944 582 Pfam PF02374 Anion-transporting ATPase 474 581 8.8E-7 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 THSYN_RS14330 61899fc8065aa729d58ea5e253cd6944 582 Pfam PF02374 Anion-transporting ATPase 9 291 7.4E-64 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 THSYN_RS14330 61899fc8065aa729d58ea5e253cd6944 582 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 12 291 6.6E-68 T 29-03-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 THSYN_RS14330 61899fc8065aa729d58ea5e253cd6944 582 PIRSF PIRSF001327 2 582 1.5E-252 T 29-03-2018 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 THSYN_RS14330 61899fc8065aa729d58ea5e253cd6944 582 SMART SM00382 7 228 0.4 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS14330 61899fc8065aa729d58ea5e253cd6944 582 SMART SM00382 324 529 0.52 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS14330 61899fc8065aa729d58ea5e253cd6944 582 SUPERFAMILY SSF52540 313 534 2.44E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14330 61899fc8065aa729d58ea5e253cd6944 582 Gene3D G3DSA:3.40.50.300 311 581 1.4E-44 T 29-03-2018 THSYN_RS14330 61899fc8065aa729d58ea5e253cd6944 582 SUPERFAMILY SSF52540 6 241 4.32E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14330 61899fc8065aa729d58ea5e253cd6944 582 Gene3D G3DSA:3.40.50.300 3 293 1.0E-55 T 29-03-2018 THSYN_RS14330 61899fc8065aa729d58ea5e253cd6944 582 TIGRFAM TIGR04291 arsen_driv_ArsA: arsenical pump-driving ATPase 8 568 2.4E-234 T 29-03-2018 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 THSYN_RS21595 dbac5fe3db5197a328453cade078883c 106 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 27 38 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS21595 dbac5fe3db5197a328453cade078883c 106 Gene3D G3DSA:3.30.70.20 22 82 4.1E-11 T 29-03-2018 THSYN_RS21595 dbac5fe3db5197a328453cade078883c 106 Gene3D G3DSA:3.30.70.20 83 104 9.3E-4 T 29-03-2018 THSYN_RS21595 dbac5fe3db5197a328453cade078883c 106 SUPERFAMILY SSF46548 10 101 2.72E-16 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS21595 dbac5fe3db5197a328453cade078883c 106 TIGRFAM TIGR02936 fdxN_nitrog: ferredoxin III, nif-specific 6 101 8.7E-34 T 29-03-2018 IPR014283 Ferredoxin III 4[4Fe-4S], nif-specific THSYN_RS21595 dbac5fe3db5197a328453cade078883c 106 Pfam PF13237 4Fe-4S dicluster domain 22 93 1.3E-11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS21595 dbac5fe3db5197a328453cade078883c 106 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 82 93 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SUPERFAMILY SSF48452 402 574 4.8E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SUPERFAMILY SSF48452 195 392 1.14E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 Pfam PF13432 Tetratricopeptide repeat 406 469 1.5E-4 T 29-03-2018 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 Gene3D G3DSA:1.25.40.10 47 233 5.7E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 Pfam PF14559 Tetratricopeptide repeat 176 241 2.2E-8 T 29-03-2018 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 Pfam PF14559 Tetratricopeptide repeat 889 956 1.0E-6 T 29-03-2018 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 Gene3D G3DSA:1.25.40.10 386 521 6.8E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 Gene3D G3DSA:1.25.40.10 522 637 6.5E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 Gene3D G3DSA:1.25.40.120 788 960 9.6E-22 T 29-03-2018 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 Gene3D G3DSA:1.25.40.120 638 787 3.6E-7 T 29-03-2018 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SMART SM00028 266 299 340.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SMART SM00028 129 162 100.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SMART SM00028 402 435 58.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SMART SM00028 232 265 55.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SMART SM00028 811 844 11.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SMART SM00028 538 571 0.0091 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SMART SM00028 164 197 28.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SMART SM00028 743 776 380.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SMART SM00028 878 911 490.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SMART SM00028 198 231 70.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 Gene3D G3DSA:1.25.40.10 234 299 1.3E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SUPERFAMILY SSF48452 87 228 9.49E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SUPERFAMILY SSF48452 750 925 4.17E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 SUPERFAMILY SSF48452 595 715 4.17E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS25565 a3215ba78f17b8c14c51f09983533f90 963 Gene3D G3DSA:1.25.40.10 300 385 1.6E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23885 435514a83dba716af391cf4a1f0867e3 233 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.51 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 THSYN_RS23885 435514a83dba716af391cf4a1f0867e3 233 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 2.0E-39 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23885 435514a83dba716af391cf4a1f0867e3 233 Gene3D G3DSA:3.30.300.20 17 107 9.9E-28 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta THSYN_RS23885 435514a83dba716af391cf4a1f0867e3 233 Pfam PF07650 KH domain 39 111 9.0E-19 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23885 435514a83dba716af391cf4a1f0867e3 233 SMART SM00322 60 125 9.6E-9 T 29-03-2018 IPR004087 K Homology domain GO:0003676 THSYN_RS23885 435514a83dba716af391cf4a1f0867e3 233 SUPERFAMILY SSF54821 108 206 2.75E-39 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23885 435514a83dba716af391cf4a1f0867e3 233 Gene3D G3DSA:3.30.1140.32 108 207 8.1E-38 T 29-03-2018 THSYN_RS23885 435514a83dba716af391cf4a1f0867e3 233 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23885 435514a83dba716af391cf4a1f0867e3 233 SUPERFAMILY SSF54814 2 106 8.63E-38 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 THSYN_RS23885 435514a83dba716af391cf4a1f0867e3 233 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 5.2E-97 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 Gene3D G3DSA:3.40.50.300 201 346 4.7E-30 T 29-03-2018 THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 Pfam PF09382 RQC domain 401 511 1.3E-38 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 SMART SM00341 529 609 2.1E-19 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 456 9.6E-158 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 Gene3D G3DSA:1.10.10.10 636 705 7.1E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 Pfam PF16124 RecQ zinc-binding 336 398 4.2E-21 T 29-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 SMART SM00487 14 210 1.6E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 Gene3D G3DSA:1.10.150.80 516 611 1.4E-25 T 29-03-2018 THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 SMART SM00490 243 324 4.8E-26 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 SUPERFAMILY SSF47819 523 609 8.97E-24 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 Gene3D G3DSA:3.40.50.300 1 200 2.8E-34 T 29-03-2018 THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 Pfam PF00570 HRDC domain 534 597 2.8E-21 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 SMART SM00956 405 508 2.4E-53 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 SUPERFAMILY SSF52540 7 157 1.41E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 SUPERFAMILY SSF52540 298 341 1.41E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 Pfam PF14493 Helix-turn-helix domain 642 734 1.1E-20 T 29-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 SUPERFAMILY SSF52540 200 451 2.43E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 Pfam PF00270 DEAD/DEAH box helicase 21 177 1.5E-19 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 7 599 2.6E-250 T 29-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 Pfam PF00271 Helicase conserved C-terminal domain 218 323 1.1E-16 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS05940 13807250d0d0f4d4dc2552c4df53586d 739 Gene3D G3DSA:1.10.10.10 347 515 1.1E-50 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS27920 3bcefa0f0a54cb73f24b323fe60c9eae 328 SUPERFAMILY SSF52540 18 301 3.94E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27920 3bcefa0f0a54cb73f24b323fe60c9eae 328 Gene3D G3DSA:3.40.50.300 30 196 2.3E-28 T 29-03-2018 THSYN_RS27920 3bcefa0f0a54cb73f24b323fe60c9eae 328 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 49 179 6.4E-63 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 THSYN_RS27920 3bcefa0f0a54cb73f24b323fe60c9eae 328 PIRSF PIRSF002849 1 328 4.4E-126 T 29-03-2018 THSYN_RS27920 3bcefa0f0a54cb73f24b323fe60c9eae 328 Gene3D G3DSA:1.10.8.300 215 323 8.8E-29 T 29-03-2018 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 61 157 5.4E-22 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 261 333 1.0E-31 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 Gene3D G3DSA:1.10.150.20 251 333 4.4E-28 T 29-03-2018 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 SUPERFAMILY SSF47789 256 331 1.57E-25 T 29-03-2018 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 256 313 8.5E-23 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 SUPERFAMILY SSF56553 55 179 5.76E-37 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 SMART SM00662 25 235 8.3E-86 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 31 229 4.5E-22 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 SUPERFAMILY SSF55257 11 55 2.16E-26 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 SUPERFAMILY SSF55257 180 232 2.16E-26 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 322 33.373 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 26 321 1.5E-100 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 Gene3D G3DSA:3.30.1360.10 123 232 3.3E-25 T 29-03-2018 THSYN_RS23790 799e0a4a820103b26c7e772753cbc0f8 337 Gene3D G3DSA:3.30.1360.10 4 113 9.9E-17 T 29-03-2018 THSYN_RS12350 2b7e329ee59dc16dd50d0325e987e34c 247 SUPERFAMILY SSF63380 3 100 3.58E-25 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THSYN_RS12350 2b7e329ee59dc16dd50d0325e987e34c 247 SUPERFAMILY SSF52343 104 237 1.06E-33 T 29-03-2018 THSYN_RS12350 2b7e329ee59dc16dd50d0325e987e34c 247 Gene3D G3DSA:2.40.30.10 1 95 7.4E-20 T 29-03-2018 THSYN_RS12350 2b7e329ee59dc16dd50d0325e987e34c 247 Gene3D G3DSA:3.40.50.80 97 247 1.3E-22 T 29-03-2018 THSYN_RS12350 2b7e329ee59dc16dd50d0325e987e34c 247 Pfam PF00970 Oxidoreductase FAD-binding domain 20 92 6.0E-9 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 THSYN_RS12350 2b7e329ee59dc16dd50d0325e987e34c 247 Pfam PF00175 Oxidoreductase NAD-binding domain 111 222 8.4E-15 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THSYN_RS28610 375d8d76d5a4c7aa02f73f6ca0cdaf55 120 Gene3D G3DSA:3.30.2310.20 39 120 3.6E-12 T 29-03-2018 THSYN_RS28610 375d8d76d5a4c7aa02f73f6ca0cdaf55 120 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 41 120 4.8E-25 T 29-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 THSYN_RS28610 375d8d76d5a4c7aa02f73f6ca0cdaf55 120 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 41 120 7.1E-28 T 29-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 THSYN_RS28610 375d8d76d5a4c7aa02f73f6ca0cdaf55 120 SUPERFAMILY SSF143011 40 119 1.53E-16 T 29-03-2018 IPR035095 Toxin RelE-like domain THSYN_RS03290 70fde7f47a28f908bf064bf24ace32a5 795 Pfam PF12161 HsdM N-terminal domain 8 123 2.7E-15 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS03290 70fde7f47a28f908bf064bf24ace32a5 795 Gene3D G3DSA:3.40.50.150 157 443 5.2E-58 T 29-03-2018 THSYN_RS03290 70fde7f47a28f908bf064bf24ace32a5 795 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 159 175 4.3E-17 T 29-03-2018 THSYN_RS03290 70fde7f47a28f908bf064bf24ace32a5 795 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 300 324 4.3E-17 T 29-03-2018 THSYN_RS03290 70fde7f47a28f908bf064bf24ace32a5 795 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 187 201 4.3E-17 T 29-03-2018 THSYN_RS03290 70fde7f47a28f908bf064bf24ace32a5 795 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 263 275 4.3E-17 T 29-03-2018 THSYN_RS03290 70fde7f47a28f908bf064bf24ace32a5 795 Pfam PF02384 N-6 DNA Methylase 136 446 5.1E-98 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS03290 70fde7f47a28f908bf064bf24ace32a5 795 SUPERFAMILY SSF53335 8 488 1.3E-122 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS10710 1bc671c1a598e4b2a21e2d9385c0deeb 150 Gene3D G3DSA:3.40.50.1010 1 133 9.3E-13 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS10710 1bc671c1a598e4b2a21e2d9385c0deeb 150 SUPERFAMILY SSF88723 5 135 6.54E-11 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 Gene3D G3DSA:3.40.50.300 577 822 1.6E-37 T 29-03-2018 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 SUPERFAMILY SSF52540 577 808 3.47E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 Gene3D G3DSA:1.10.1420.10 274 416 5.1E-33 T 29-03-2018 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 SUPERFAMILY SSF48334 278 575 5.1E-86 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 Pfam PF05188 MutS domain II 135 264 1.8E-24 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 SMART SM00534 617 804 3.0E-109 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 Gene3D G3DSA:3.30.420.110 139 273 6.4E-26 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 SMART SM00533 294 601 3.8E-93 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 Pfam PF05192 MutS domain III 280 569 1.6E-33 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 Pfam PF05190 MutS family domain IV 438 529 1.6E-29 T 29-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 Pfam PF00488 MutS domain V 620 807 3.5E-79 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 Pfam PF01624 MutS domain I 15 126 1.4E-40 T 29-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 PIRSF PIRSF037677 236 827 1.7E-116 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 PIRSF PIRSF037677 7 217 7.7E-27 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 Gene3D G3DSA:3.40.1170.10 4 138 6.6E-46 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 SUPERFAMILY SSF55271 8 122 1.7E-42 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 14 860 24.955 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 698 714 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 14 865 0.0 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 Gene3D G3DSA:1.10.1420.10 417 545 2.6E-29 T 29-03-2018 THSYN_RS16445 4b1d5563dcdbc011640bf666f9cfac6f 868 SUPERFAMILY SSF53150 121 277 9.29E-41 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 THSYN_RS17055 2eb17bfa223c46aafb9ae8b0b6725a67 353 Pfam PF13439 Glycosyltransferase Family 4 7 166 7.8E-19 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS17055 2eb17bfa223c46aafb9ae8b0b6725a67 353 Gene3D G3DSA:3.40.50.2000 173 333 2.5E-43 T 29-03-2018 THSYN_RS17055 2eb17bfa223c46aafb9ae8b0b6725a67 353 SUPERFAMILY SSF53756 6 353 1.01E-71 T 29-03-2018 THSYN_RS17055 2eb17bfa223c46aafb9ae8b0b6725a67 353 Pfam PF00534 Glycosyl transferases group 1 188 320 1.1E-33 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS17055 2eb17bfa223c46aafb9ae8b0b6725a67 353 Gene3D G3DSA:3.40.50.2000 2 172 1.6E-18 T 29-03-2018 THSYN_RS12570 9515c2f0cfb285c90682b7f10fc63dbb 190 SUPERFAMILY SSF55154 6 172 4.58E-8 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 THSYN_RS12570 9515c2f0cfb285c90682b7f10fc63dbb 190 Gene3D G3DSA:2.40.320.10 2 185 6.6E-11 T 29-03-2018 THSYN_RS26495 ebe1b07a0e76dbc00d7cb29e47a0ac8a 536 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 11 232 5.8E-47 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related THSYN_RS26495 ebe1b07a0e76dbc00d7cb29e47a0ac8a 536 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 275 492 1.3E-81 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related THSYN_RS26495 ebe1b07a0e76dbc00d7cb29e47a0ac8a 536 SUPERFAMILY SSF52540 40 217 8.57E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26495 ebe1b07a0e76dbc00d7cb29e47a0ac8a 536 SUPERFAMILY SSF52540 302 491 2.99E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26495 ebe1b07a0e76dbc00d7cb29e47a0ac8a 536 Gene3D G3DSA:3.40.50.300 251 501 1.2E-83 T 29-03-2018 THSYN_RS26495 ebe1b07a0e76dbc00d7cb29e47a0ac8a 536 Gene3D G3DSA:3.40.50.300 3 250 3.3E-60 T 29-03-2018 THSYN_RS26495 ebe1b07a0e76dbc00d7cb29e47a0ac8a 536 TIGRFAM TIGR03708 poly_P_AMP_trns: polyphosphate:AMP phosphotransferase 2 494 1.4E-208 T 29-03-2018 IPR022489 Polyphosphate:AMP phosphotransferase GO:0006797|GO:0043751 THSYN_RS22515 d2704e6a7cbd2c262b7eb9fc60fd32aa 382 Pfam PF00849 RNA pseudouridylate synthase 147 304 3.8E-28 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS22515 d2704e6a7cbd2c262b7eb9fc60fd32aa 382 SUPERFAMILY SSF55174 65 116 1.85E-8 T 29-03-2018 THSYN_RS22515 d2704e6a7cbd2c262b7eb9fc60fd32aa 382 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 62 367 2.6E-73 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS22515 d2704e6a7cbd2c262b7eb9fc60fd32aa 382 Gene3D G3DSA:3.30.2350.10 137 371 6.9E-60 T 29-03-2018 THSYN_RS22515 d2704e6a7cbd2c262b7eb9fc60fd32aa 382 SMART SM00363 66 125 1.5E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS22515 d2704e6a7cbd2c262b7eb9fc60fd32aa 382 Gene3D G3DSA:3.10.290.10 53 127 1.8E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS22515 d2704e6a7cbd2c262b7eb9fc60fd32aa 382 Pfam PF01479 S4 domain 66 112 2.6E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS22515 d2704e6a7cbd2c262b7eb9fc60fd32aa 382 SUPERFAMILY SSF55120 138 367 8.8E-57 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS03220 654fb3e2ed4d7e1764729523475958ef 136 Pfam PF01381 Helix-turn-helix 24 78 6.6E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS03220 654fb3e2ed4d7e1764729523475958ef 136 SMART SM00530 23 78 3.6E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS03220 654fb3e2ed4d7e1764729523475958ef 136 Gene3D G3DSA:1.10.260.40 15 88 1.8E-20 T 29-03-2018 THSYN_RS03220 654fb3e2ed4d7e1764729523475958ef 136 SUPERFAMILY SSF47413 17 83 5.36E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS15495 54b27aa465d18036ff7e1e6bab76eafb 668 SMART SM00382 451 583 9.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS15495 54b27aa465d18036ff7e1e6bab76eafb 668 Gene3D G3DSA:1.10.8.60 590 650 8.5E-4 T 29-03-2018 THSYN_RS15495 54b27aa465d18036ff7e1e6bab76eafb 668 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 455 580 4.5E-26 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS15495 54b27aa465d18036ff7e1e6bab76eafb 668 Gene3D G3DSA:3.40.50.300 390 589 4.0E-30 T 29-03-2018 THSYN_RS15495 54b27aa465d18036ff7e1e6bab76eafb 668 SUPERFAMILY SSF52540 407 648 1.93E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29485 9c462b939a6ee2a5186897f571e0566a 338 Gene3D G3DSA:3.20.20.210 1 338 1.2E-67 T 29-03-2018 THSYN_RS29485 9c462b939a6ee2a5186897f571e0566a 338 SUPERFAMILY SSF51726 1 337 1.57E-60 T 29-03-2018 THSYN_RS29485 9c462b939a6ee2a5186897f571e0566a 338 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 4 336 2.1E-71 T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THSYN_RS23130 be384e5c9dd19f19231e81b24fb38b25 179 Gene3D G3DSA:3.40.630.30 2 174 1.3E-12 T 29-03-2018 THSYN_RS23130 be384e5c9dd19f19231e81b24fb38b25 179 Pfam PF13302 Acetyltransferase (GNAT) domain 9 141 4.8E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS23130 be384e5c9dd19f19231e81b24fb38b25 179 SUPERFAMILY SSF55729 5 150 1.91E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS15085 ccc326d5dc15638d9ea42cc57c162c79 282 Pfam PF01261 Xylose isomerase-like TIM barrel 21 234 5.0E-36 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain THSYN_RS15085 ccc326d5dc15638d9ea42cc57c162c79 282 SUPERFAMILY SSF51658 3 277 7.2E-58 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain THSYN_RS15085 ccc326d5dc15638d9ea42cc57c162c79 282 Gene3D G3DSA:3.20.20.150 1 281 1.1E-65 T 29-03-2018 THSYN_RS17400 522f2b6b4efce677cd7b315398259343 173 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 2 164 2.5E-70 T 29-03-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria THSYN_RS17400 522f2b6b4efce677cd7b315398259343 173 Pfam PF03350 Uncharacterized protein family, UPF0114 9 124 7.1E-33 T 29-03-2018 IPR005134 Uncharacterised protein family UPF0114 THSYN_RS17400 522f2b6b4efce677cd7b315398259343 173 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 165 80.995 T 29-03-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria THSYN_RS29115 6927fc61a9d34568ddfc817dcadd9fc8 456 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 450 42.444 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 THSYN_RS29115 6927fc61a9d34568ddfc817dcadd9fc8 456 Gene3D G3DSA:3.90.550.10 1 242 1.2E-49 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS29115 6927fc61a9d34568ddfc817dcadd9fc8 456 Gene3D G3DSA:2.160.10.10 322 438 2.9E-32 T 29-03-2018 THSYN_RS29115 6927fc61a9d34568ddfc817dcadd9fc8 456 SUPERFAMILY SSF53448 1 250 1.91E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS29115 6927fc61a9d34568ddfc817dcadd9fc8 456 Pfam PF12804 MobA-like NTP transferase domain 5 128 5.8E-25 T 29-03-2018 IPR025877 MobA-like NTP transferase THSYN_RS29115 6927fc61a9d34568ddfc817dcadd9fc8 456 Gene3D G3DSA:2.160.10.10 243 321 3.0E-17 T 29-03-2018 THSYN_RS29115 6927fc61a9d34568ddfc817dcadd9fc8 456 SUPERFAMILY SSF51161 253 435 7.07E-52 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS29115 6927fc61a9d34568ddfc817dcadd9fc8 456 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 5 452 2.9E-187 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 THSYN_RS29115 6927fc61a9d34568ddfc817dcadd9fc8 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 393 427 2.9E-9 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS29115 6927fc61a9d34568ddfc817dcadd9fc8 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 299 331 1.8E-5 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS33000 84e7e2eea671d6908355a100f884b7b7 421 SUPERFAMILY SSF53822 67 385 8.07E-27 T 29-03-2018 IPR028082 Periplasmic binding protein-like I THSYN_RS33000 84e7e2eea671d6908355a100f884b7b7 421 Pfam PF13458 Periplasmic binding protein 80 234 1.4E-7 T 29-03-2018 IPR028081 Leucine-binding protein domain THSYN_RS33000 84e7e2eea671d6908355a100f884b7b7 421 Gene3D G3DSA:3.40.50.2300 256 354 0.0081 T 29-03-2018 THSYN_RS33000 84e7e2eea671d6908355a100f884b7b7 421 Gene3D G3DSA:3.40.50.2300 87 255 8.5E-10 T 29-03-2018 THSYN_RS33000 84e7e2eea671d6908355a100f884b7b7 421 TIGRFAM TIGR03863 PQQ_ABC_bind: ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system 73 418 1.3E-140 T 29-03-2018 IPR022478 ABC transporter, substrate-binding protein, PQQ-dependent alcohol dehydrogenase system THSYN_RS16610 e3d9b36c2f7994e7126e7bd75f89e6e8 364 SUPERFAMILY SSF52540 13 188 3.31E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16610 e3d9b36c2f7994e7126e7bd75f89e6e8 364 Gene3D G3DSA:3.40.50.300 10 177 1.7E-11 T 29-03-2018 THSYN_RS16610 e3d9b36c2f7994e7126e7bd75f89e6e8 364 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 30 106 2.6E-5 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS11705 19c5c410295d5619e545e88d71573781 658 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 47 72 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THSYN_RS11705 19c5c410295d5619e545e88d71573781 658 SUPERFAMILY SSF56762 6 506 2.22E-138 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS11705 19c5c410295d5619e545e88d71573781 658 SUPERFAMILY SSF56762 533 628 2.22E-138 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS11705 19c5c410295d5619e545e88d71573781 658 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 619 628 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THSYN_RS11705 19c5c410295d5619e545e88d71573781 658 Gene3D G3DSA:1.10.645.10 1 628 2.8E-158 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS11705 19c5c410295d5619e545e88d71573781 658 Pfam PF00374 Nickel-dependent hydrogenase 47 628 9.9E-176 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THSYN_RS26695 29562f1b2ef42613d4ccfd3ec118638e 422 Gene3D G3DSA:3.40.50.300 23 163 1.3E-13 T 29-03-2018 THSYN_RS26695 29562f1b2ef42613d4ccfd3ec118638e 422 SUPERFAMILY SSF52540 31 158 4.91E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26695 29562f1b2ef42613d4ccfd3ec118638e 422 Pfam PF01926 50S ribosome-binding GTPase 47 133 9.0E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS19320 1655104448e9666f305849cd6875dfba 242 SMART SM00100 12 133 1.8E-8 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS19320 1655104448e9666f305849cd6875dfba 242 SUPERFAMILY SSF51206 8 137 6.15E-15 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like THSYN_RS19320 1655104448e9666f305849cd6875dfba 242 Gene3D G3DSA:2.60.120.10 6 159 8.8E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS19320 1655104448e9666f305849cd6875dfba 242 Pfam PF00027 Cyclic nucleotide-binding domain 33 117 3.5E-7 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS19320 1655104448e9666f305849cd6875dfba 242 Pfam PF13545 Crp-like helix-turn-helix domain 150 217 2.3E-14 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS19320 1655104448e9666f305849cd6875dfba 242 Gene3D G3DSA:1.10.10.10 160 236 1.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19320 1655104448e9666f305849cd6875dfba 242 SMART SM00419 162 210 2.1E-4 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS19320 1655104448e9666f305849cd6875dfba 242 SUPERFAMILY SSF46785 147 222 3.05E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS29195 64c25ec54a558dd8abcec7dde66269e6 305 SMART SM00470 49 139 2.3E-36 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS29195 64c25ec54a558dd8abcec7dde66269e6 305 Pfam PF02195 ParB-like nuclease domain 51 139 3.9E-28 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS29195 64c25ec54a558dd8abcec7dde66269e6 305 SUPERFAMILY SSF110849 48 183 3.14E-33 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS29195 64c25ec54a558dd8abcec7dde66269e6 305 Gene3D G3DSA:1.10.10.730 140 187 3.4E-18 T 29-03-2018 THSYN_RS29195 64c25ec54a558dd8abcec7dde66269e6 305 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 48 222 2.5E-58 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 THSYN_RS29195 64c25ec54a558dd8abcec7dde66269e6 305 Gene3D G3DSA:3.90.1530.10 39 139 4.3E-36 T 29-03-2018 THSYN_RS20460 fe82b4beba379a1ba05bc94a510f41da 868 SUPERFAMILY SSF53649 481 652 4.45E-5 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS20460 fe82b4beba379a1ba05bc94a510f41da 868 Pfam PF08665 PglZ domain 481 654 2.5E-58 T 29-03-2018 IPR013973 PglZ domain THSYN_RS20460 fe82b4beba379a1ba05bc94a510f41da 868 Gene3D G3DSA:3.40.720.10 183 714 8.8E-5 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS20460 fe82b4beba379a1ba05bc94a510f41da 868 TIGRFAM TIGR02687 TIGR02687: TIGR02687 family protein 4 859 1.1E-262 T 29-03-2018 IPR014060 Conserved hypothetical protein CHP02687 THSYN_RS02285 8b378c90687394044681d650035fd0a8 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 5.4E-17 T 29-03-2018 THSYN_RS02285 8b378c90687394044681d650035fd0a8 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 5.4E-17 T 29-03-2018 THSYN_RS02285 8b378c90687394044681d650035fd0a8 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 5.4E-17 T 29-03-2018 THSYN_RS02285 8b378c90687394044681d650035fd0a8 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 5.4E-17 T 29-03-2018 THSYN_RS02285 8b378c90687394044681d650035fd0a8 415 Pfam PF01494 FAD binding domain 5 341 4.6E-25 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 THSYN_RS02285 8b378c90687394044681d650035fd0a8 415 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 391 2.2E-124 T 29-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 THSYN_RS02285 8b378c90687394044681d650035fd0a8 415 SUPERFAMILY SSF51905 2 178 1.3E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS02285 8b378c90687394044681d650035fd0a8 415 SUPERFAMILY SSF51905 277 397 1.3E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS02285 8b378c90687394044681d650035fd0a8 415 Gene3D G3DSA:3.50.50.60 1 361 2.7E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS02285 8b378c90687394044681d650035fd0a8 415 TIGRFAM TIGR01984 UbiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase 5 391 1.9E-126 T 29-03-2018 IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase GO:0006744|GO:0008681 THSYN_RS02285 8b378c90687394044681d650035fd0a8 415 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 295 308 - T 29-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 THSYN_RS10540 f9bc56a56c4004d839bfa7cfce9cb11b 593 Gene3D G3DSA:3.20.20.70 157 481 4.2E-29 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS10540 f9bc56a56c4004d839bfa7cfce9cb11b 593 SUPERFAMILY SSF102114 217 443 2.88E-28 T 29-03-2018 THSYN_RS10540 f9bc56a56c4004d839bfa7cfce9cb11b 593 SMART SM00729 207 426 3.1E-17 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS10540 f9bc56a56c4004d839bfa7cfce9cb11b 593 Pfam PF04055 Radical SAM superfamily 218 379 1.5E-12 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS06055 562f80cad32380a7b233c97f960634c2 407 SMART SM00255 3 129 0.0079 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS06055 562f80cad32380a7b233c97f960634c2 407 SUPERFAMILY SSF56436 171 400 6.83E-68 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS06055 562f80cad32380a7b233c97f960634c2 407 Gene3D G3DSA:3.40.50.10140 4 128 8.5E-20 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS06055 562f80cad32380a7b233c97f960634c2 407 Gene3D G3DSA:3.90.1580.10 160 233 6.8E-13 T 29-03-2018 THSYN_RS06055 562f80cad32380a7b233c97f960634c2 407 Gene3D G3DSA:3.90.1580.10 234 406 1.9E-54 T 29-03-2018 THSYN_RS06055 562f80cad32380a7b233c97f960634c2 407 SUPERFAMILY SSF52200 5 101 3.66E-19 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS06055 562f80cad32380a7b233c97f960634c2 407 Pfam PF03781 Sulfatase-modifying factor enzyme 1 171 397 6.3E-58 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS06055 562f80cad32380a7b233c97f960634c2 407 Pfam PF13676 TIR domain 6 106 8.1E-27 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS28990 09d935f2d9ee116a08a8c8df03caead7 383 Pfam PF13439 Glycosyltransferase Family 4 13 180 2.8E-15 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS28990 09d935f2d9ee116a08a8c8df03caead7 383 SUPERFAMILY SSF53756 2 378 6.67E-70 T 29-03-2018 THSYN_RS28990 09d935f2d9ee116a08a8c8df03caead7 383 Gene3D G3DSA:3.40.50.2000 186 360 8.2E-40 T 29-03-2018 THSYN_RS28990 09d935f2d9ee116a08a8c8df03caead7 383 Pfam PF13692 Glycosyl transferases group 1 203 341 3.9E-24 T 29-03-2018 THSYN_RS28990 09d935f2d9ee116a08a8c8df03caead7 383 Gene3D G3DSA:3.40.50.2000 1 185 3.9E-16 T 29-03-2018 THSYN_RS28095 63ea5f0cb830a313162c23981af7b782 621 Gene3D G3DSA:3.10.580.10 147 320 5.6E-26 T 29-03-2018 THSYN_RS28095 63ea5f0cb830a313162c23981af7b782 621 Pfam PF03445 Putative nucleotidyltransferase DUF294 300 434 5.3E-48 T 29-03-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 THSYN_RS28095 63ea5f0cb830a313162c23981af7b782 621 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 472 615 6.0E-49 T 29-03-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding THSYN_RS28095 63ea5f0cb830a313162c23981af7b782 621 Gene3D G3DSA:2.60.120.10 2 146 1.6E-12 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS28095 63ea5f0cb830a313162c23981af7b782 621 SUPERFAMILY SSF51206 10 141 6.02E-16 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like THSYN_RS28095 63ea5f0cb830a313162c23981af7b782 621 Gene3D G3DSA:3.30.460.10 321 465 0.0019 T 29-03-2018 THSYN_RS28095 63ea5f0cb830a313162c23981af7b782 621 SUPERFAMILY SSF54631 154 273 1.21E-28 T 29-03-2018 THSYN_RS28095 63ea5f0cb830a313162c23981af7b782 621 SMART SM00116 227 274 0.22 T 29-03-2018 IPR000644 CBS domain THSYN_RS28095 63ea5f0cb830a313162c23981af7b782 621 SMART SM00116 163 210 2.7E-8 T 29-03-2018 IPR000644 CBS domain THSYN_RS28095 63ea5f0cb830a313162c23981af7b782 621 Pfam PF00571 CBS domain 220 273 4.5E-7 T 29-03-2018 IPR000644 CBS domain THSYN_RS28095 63ea5f0cb830a313162c23981af7b782 621 Pfam PF00571 CBS domain 156 208 1.7E-9 T 29-03-2018 IPR000644 CBS domain THSYN_RS10690 6e240c05a18419f01c8f57d41ff037a3 629 Gene3D G3DSA:1.25.40.10 101 348 8.4E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS10690 6e240c05a18419f01c8f57d41ff037a3 629 Gene3D G3DSA:1.25.40.10 349 624 2.0E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS10690 6e240c05a18419f01c8f57d41ff037a3 629 SUPERFAMILY SSF48452 148 161 5.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS10690 6e240c05a18419f01c8f57d41ff037a3 629 SUPERFAMILY SSF48452 260 324 5.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS10690 6e240c05a18419f01c8f57d41ff037a3 629 SUPERFAMILY SSF48452 200 219 5.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS10690 6e240c05a18419f01c8f57d41ff037a3 629 SUPERFAMILY SSF48452 401 446 5.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27900 2b02d830251224a293e65f3b95ee2e24 308 SUPERFAMILY SSF53474 25 302 9.39E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS27900 2b02d830251224a293e65f3b95ee2e24 308 Pfam PF12697 Alpha/beta hydrolase family 50 287 1.8E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS27900 2b02d830251224a293e65f3b95ee2e24 308 Gene3D G3DSA:3.40.50.1820 18 301 2.5E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 Gene3D G3DSA:3.30.2090.10 182 268 2.9E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 Gene3D G3DSA:3.30.70.1430 42 142 4.5E-17 T 29-03-2018 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1027 0.0 T 29-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 SUPERFAMILY SSF82714 185 265 2.09E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 SUPERFAMILY SSF82866 800 1026 2.62E-56 T 29-03-2018 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 Pfam PF00873 AcrB/AcrD/AcrF family 6 1019 4.6E-287 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 SUPERFAMILY SSF82714 718 800 1.1E-10 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 Gene3D G3DSA:1.20.1640.10 286 507 3.1E-40 T 29-03-2018 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 Gene3D G3DSA:1.20.1640.10 814 1032 3.9E-39 T 29-03-2018 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 Gene3D G3DSA:3.30.70.1430 560 664 6.9E-13 T 29-03-2018 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 SUPERFAMILY SSF82866 291 499 2.49E-40 T 29-03-2018 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 SUPERFAMILY SSF82693 43 127 1.91E-17 T 29-03-2018 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 Gene3D G3DSA:3.30.2090.10 715 803 9.0E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 616 630 4.2E-30 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 545 562 4.2E-30 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 4.2E-30 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 4.2E-30 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 4.2E-30 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 4.2E-30 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 4.2E-30 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 SUPERFAMILY SSF82693 139 182 4.97E-19 T 29-03-2018 THSYN_RS30335 1ef363318d029e46314ca2eb5d0980d0 1032 SUPERFAMILY SSF82693 268 324 4.97E-19 T 29-03-2018 THSYN_RS00995 410c2fa99e4c6b0459b6be669c6a5bec 109 SUPERFAMILY SSF102829 8 97 1.83E-23 T 29-03-2018 IPR007838 Cell division protein ZapA-like THSYN_RS00995 410c2fa99e4c6b0459b6be669c6a5bec 109 Pfam PF05164 Cell division protein ZapA 8 92 1.7E-22 T 29-03-2018 IPR007838 Cell division protein ZapA-like THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 174 188 2.1E-51 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 402 421 2.1E-51 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 142 162 2.1E-51 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 240 267 2.1E-51 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 206 220 2.1E-51 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 Pfam PF00308 Bacterial dnaA protein 110 326 3.6E-90 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 Pfam PF11638 DnaA N-terminal domain 2 62 1.7E-16 T 29-03-2018 IPR024633 DnaA N-terminal domain THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 354 421 1.7E-30 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 1 443 32.534 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 Gene3D G3DSA:3.40.50.300 106 273 3.7E-16 T 29-03-2018 THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 SMART SM00382 141 350 0.0025 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 SMART SM00760 352 421 2.6E-39 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 ProSitePatterns PS01008 DnaA protein signature. 402 421 - T 29-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 SUPERFAMILY SSF52540 108 321 5.07E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 4 442 2.3E-172 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 SUPERFAMILY SSF48295 341 443 8.89E-35 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 Gene3D G3DSA:1.10.1750.10 346 443 1.1E-34 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 THSYN_RS00005 186c2668c54c7a849770e77caefcb7f8 444 Gene3D G3DSA:1.10.8.60 275 345 7.3E-25 T 29-03-2018 THSYN_RS00540 682bc9740c08a793f73596b95e05f158 524 Gene3D G3DSA:3.40.50.300 23 392 1.9E-9 T 29-03-2018 THSYN_RS00540 682bc9740c08a793f73596b95e05f158 524 Pfam PF14516 AAA-like domain 40 343 3.0E-11 T 29-03-2018 THSYN_RS00540 682bc9740c08a793f73596b95e05f158 524 SUPERFAMILY SSF52540 26 271 3.54E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS32590 0c2d2beb21a8d6a14865008109efc3f7 404 Gene3D G3DSA:1.20.1600.10 32 334 1.4E-24 T 29-03-2018 THSYN_RS32590 0c2d2beb21a8d6a14865008109efc3f7 404 SUPERFAMILY SSF111369 54 299 1.44E-69 T 29-03-2018 THSYN_RS32590 0c2d2beb21a8d6a14865008109efc3f7 404 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 373 2.2E-79 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS32590 0c2d2beb21a8d6a14865008109efc3f7 404 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 292 4.0E-13 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS10530 8af0de236f0ed2fefa911029aaf05b43 190 Pfam PF00691 OmpA family 65 148 7.9E-13 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS10530 8af0de236f0ed2fefa911029aaf05b43 190 SUPERFAMILY SSF103088 59 177 2.49E-16 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS10530 8af0de236f0ed2fefa911029aaf05b43 190 Gene3D G3DSA:3.30.1330.60 24 190 4.1E-18 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS10530 8af0de236f0ed2fefa911029aaf05b43 190 PRINTS PR01021 OMPA domain signature 100 115 1.7E-7 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS10530 8af0de236f0ed2fefa911029aaf05b43 190 PRINTS PR01021 OMPA domain signature 115 131 1.7E-7 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS31475 4bd715a1da7440a49e35eae33c90ed21 410 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 1.6E-12 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THSYN_RS31475 4bd715a1da7440a49e35eae33c90ed21 410 PRINTS PR00758 Arsenical pump membrane protein signature 316 338 1.6E-12 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THSYN_RS31475 4bd715a1da7440a49e35eae33c90ed21 410 PRINTS PR00758 Arsenical pump membrane protein signature 273 297 1.6E-12 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THSYN_RS31475 4bd715a1da7440a49e35eae33c90ed21 410 PRINTS PR00758 Arsenical pump membrane protein signature 174 197 1.6E-12 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THSYN_RS31475 4bd715a1da7440a49e35eae33c90ed21 410 Pfam PF03600 Citrate transporter 21 352 4.2E-32 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 Gene3D G3DSA:1.20.1250.20 1 198 3.5E-9 T 29-03-2018 THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 Gene3D G3DSA:3.40.50.980 800 957 2.4E-43 T 29-03-2018 THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 Pfam PF00501 AMP-binding enzyme 630 1050 9.8E-73 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 Pfam PF01553 Acyltransferase 432 557 2.7E-22 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 ProSitePatterns PS00455 Putative AMP-binding domain signature. 794 805 - T 29-03-2018 IPR020845 AMP-binding, conserved site THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 Gene3D G3DSA:3.30.300.30 1051 1150 4.9E-9 T 29-03-2018 THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 SUPERFAMILY SSF103473 13 414 2.62E-25 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 Gene3D G3DSA:2.30.38.10 958 1048 2.2E-23 T 29-03-2018 THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 Gene3D G3DSA:1.20.1250.20 222 409 3.5E-12 T 29-03-2018 THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 SUPERFAMILY SSF69593 415 609 6.41E-29 T 29-03-2018 THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 Gene3D G3DSA:3.40.50.980 620 799 7.9E-21 T 29-03-2018 THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 SMART SM00563 446 561 1.5E-31 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 Pfam PF07690 Major Facilitator Superfamily 8 376 1.8E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 SUPERFAMILY SSF56801 621 1146 4.71E-100 T 29-03-2018 THSYN_RS26735 9a5586e9694feeb4ab08c70aa15493d2 1151 Gene3D G3DSA:3.40.1130.10 410 610 5.3E-38 T 29-03-2018 THSYN_RS01430 ba3bf4a555e43e60a4e79c4275b31e9d 439 Pfam PF01547 Bacterial extracellular solute-binding protein 84 346 3.0E-20 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 THSYN_RS01430 ba3bf4a555e43e60a4e79c4275b31e9d 439 Gene3D G3DSA:3.40.190.10 139 436 5.7E-42 T 29-03-2018 THSYN_RS01430 ba3bf4a555e43e60a4e79c4275b31e9d 439 SUPERFAMILY SSF53850 29 432 3.86E-55 T 29-03-2018 THSYN_RS10125 30760afb9d29f32366b8b93c9652fcd2 266 Pfam PF05685 Putative restriction endonuclease 44 158 1.4E-18 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS10125 30760afb9d29f32366b8b93c9652fcd2 266 SUPERFAMILY SSF52980 7 167 2.47E-28 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS10125 30760afb9d29f32366b8b93c9652fcd2 266 Gene3D G3DSA:3.90.1570.10 19 175 5.8E-22 T 29-03-2018 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 SUPERFAMILY SSF51971 390 481 1.12E-9 T 29-03-2018 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 Gene3D G3DSA:3.50.50.60 240 326 2.5E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 131 1.5E-24 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 487 1.7E-218 T 29-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 Gene3D G3DSA:3.50.50.60 342 477 1.1E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 469 4.2E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 SUPERFAMILY SSF51971 142 406 4.24E-65 T 29-03-2018 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 SUPERFAMILY SSF46548 2 154 4.97E-40 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 1.8E-24 T 29-03-2018 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 PRINTS PR00419 Adrenodoxin reductase family signature 210 220 1.8E-24 T 29-03-2018 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 1.8E-24 T 29-03-2018 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 PRINTS PR00419 Adrenodoxin reductase family signature 286 300 1.8E-24 T 29-03-2018 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 Gene3D G3DSA:3.40.50.720 141 239 5.7E-22 T 29-03-2018 THSYN_RS03105 e8c756c0c4cff8e6342094f1c2156a2b 488 Gene3D G3DSA:1.10.1060.10 3 140 4.7E-42 T 29-03-2018 THSYN_RS29730 277a46dd31a928183cfbd2755ee80dd7 97 TIGRFAM TIGR02704 carboxysome_B: carboxysome peptide B 1 78 1.1E-36 T 29-03-2018 IPR014077 Carboxysome peptide B THSYN_RS29730 277a46dd31a928183cfbd2755ee80dd7 97 Gene3D G3DSA:2.40.50.220 1 92 2.6E-17 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml THSYN_RS29730 277a46dd31a928183cfbd2755ee80dd7 97 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 77 6.6E-18 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml THSYN_RS29730 277a46dd31a928183cfbd2755ee80dd7 97 SUPERFAMILY SSF159133 1 81 1.01E-21 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml THSYN_RS29730 277a46dd31a928183cfbd2755ee80dd7 97 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 10 77 4.0E-20 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml THSYN_RS17680 a5e58b0392036acdb89044614686cb9d 157 Gene3D G3DSA:3.40.50.1820 5 157 1.7E-10 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS17680 a5e58b0392036acdb89044614686cb9d 157 SUPERFAMILY SSF53474 25 108 1.12E-7 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS17680 a5e58b0392036acdb89044614686cb9d 157 Pfam PF08386 TAP-like protein 46 133 3.1E-11 T 29-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal THSYN_RS14535 68c43e26a9ec60b00430c0e519c9af93 394 SUPERFAMILY SSF52172 20 170 8.54E-40 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS14535 68c43e26a9ec60b00430c0e519c9af93 394 SUPERFAMILY SSF109604 171 361 2.73E-31 T 29-03-2018 THSYN_RS14535 68c43e26a9ec60b00430c0e519c9af93 394 SMART SM00448 21 134 5.6E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS14535 68c43e26a9ec60b00430c0e519c9af93 394 SMART SM00471 183 334 1.1E-8 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS14535 68c43e26a9ec60b00430c0e519c9af93 394 Gene3D G3DSA:3.40.50.2300 18 154 2.0E-37 T 29-03-2018 THSYN_RS14535 68c43e26a9ec60b00430c0e519c9af93 394 Pfam PF01966 HD domain 189 324 3.4E-17 T 29-03-2018 IPR006674 HD domain THSYN_RS14535 68c43e26a9ec60b00430c0e519c9af93 394 Gene3D G3DSA:1.10.3210.10 155 375 3.2E-46 T 29-03-2018 THSYN_RS14535 68c43e26a9ec60b00430c0e519c9af93 394 Pfam PF00072 Response regulator receiver domain 24 134 8.4E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS20605 fd6ea13224f4c867d489c2c7106a08c9 310 SUPERFAMILY SSF53328 1 204 5.36E-62 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THSYN_RS20605 fd6ea13224f4c867d489c2c7106a08c9 310 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 303 1.7E-90 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 THSYN_RS20605 fd6ea13224f4c867d489c2c7106a08c9 310 Gene3D G3DSA:3.40.50.170 1 206 1.1E-63 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THSYN_RS20605 fd6ea13224f4c867d489c2c7106a08c9 310 Pfam PF00551 Formyl transferase 3 181 2.3E-39 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THSYN_RS20605 fd6ea13224f4c867d489c2c7106a08c9 310 SUPERFAMILY SSF50486 205 304 2.35E-30 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 THSYN_RS20605 fd6ea13224f4c867d489c2c7106a08c9 310 Gene3D G3DSA:3.10.25.10 207 308 1.9E-31 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THSYN_RS20605 fd6ea13224f4c867d489c2c7106a08c9 310 Pfam PF02911 Formyl transferase, C-terminal domain 204 301 3.1E-28 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THSYN_RS20605 fd6ea13224f4c867d489c2c7106a08c9 310 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 305 36.397 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 SMART SM00387 27 173 4.0E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 SUPERFAMILY SSF56719 388 621 2.25E-75 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 Gene3D G3DSA:3.30.565.10 17 216 1.2E-64 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 Gene3D G3DSA:3.40.50.670 396 627 4.0E-76 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 SMART SM00433 34 624 2.0E-211 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 ProSitePatterns PS00177 DNA topoisomerase II signature. 416 424 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 3 625 4.5E-299 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 Pfam PF00204 DNA gyrase B 218 382 2.6E-40 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 558 620 6.1E-24 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 SUPERFAMILY SSF54211 217 382 2.66E-47 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 2 628 46.679 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 Gene3D G3DSA:3.30.230.10 217 391 8.5E-42 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 170 2.0E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR00418 DNA topoisomerase II family signature 109 123 8.6E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR00418 DNA topoisomerase II family signature 414 428 8.6E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR00418 DNA topoisomerase II family signature 497 514 8.6E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR00418 DNA topoisomerase II family signature 31 46 8.6E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR00418 DNA topoisomerase II family signature 562 578 8.6E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR00418 DNA topoisomerase II family signature 66 79 8.6E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR00418 DNA topoisomerase II family signature 479 495 8.6E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR00418 DNA topoisomerase II family signature 266 279 8.6E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR00418 DNA topoisomerase II family signature 517 529 8.6E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 149 164 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 192 213 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 469 481 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 503 519 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 26 39 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 537 559 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 294 310 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 135 149 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 174 191 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 448 469 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 311 326 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 238 261 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 362 387 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 PRINTS PR01098 Topoisomerase IV subunit B signature 338 361 4.9E-99 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 Pfam PF01751 Toprim domain 413 519 2.2E-12 T 29-03-2018 IPR006171 TOPRIM domain THSYN_RS23510 70559c9bc5643576e17c9de79d3974da 628 SUPERFAMILY SSF55874 4 215 6.74E-66 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 SUPERFAMILY SSF54980 409 487 7.91E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 Gene3D G3DSA:3.30.70.240 616 693 8.6E-32 T 29-03-2018 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 Pfam PF14492 Elongation Factor G, domain II 411 484 5.1E-35 T 29-03-2018 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 Pfam PF00679 Elongation factor G C-terminus 608 692 9.5E-31 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 Pfam PF03764 Elongation factor G, domain IV 486 605 8.2E-51 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 Pfam PF03144 Elongation factor Tu domain 2 331 398 4.0E-16 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 Gene3D G3DSA:3.30.70.870 409 499 1.8E-38 T 29-03-2018 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 Gene3D G3DSA:2.40.30.10 294 408 1.6E-29 T 29-03-2018 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 SUPERFAMILY SSF54211 486 606 2.45E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 Gene3D G3DSA:3.40.50.300 1 293 4.0E-59 T 29-03-2018 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 SUPERFAMILY SSF54980 610 695 2.3E-29 T 29-03-2018 IPR035647 EF-G domain III/V-like THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 Gene3D G3DSA:3.30.230.10 500 615 2.6E-46 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 SUPERFAMILY SSF50447 312 409 1.49E-34 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 SUPERFAMILY SSF50447 256 281 1.49E-34 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 1.1E-62 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 SMART SM00838 607 694 7.3E-58 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 SUPERFAMILY SSF52540 6 288 2.8E-107 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 5.3E-32 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 Hamap MF_00054_B Elongation factor G [fusA]. 6 698 112.573 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 SMART SM00889 487 605 1.8E-76 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 PRINTS PR00315 GTP-binding elongation factor signature 137 146 5.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 PRINTS PR00315 GTP-binding elongation factor signature 85 95 5.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 PRINTS PR00315 GTP-binding elongation factor signature 101 112 5.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 PRINTS PR00315 GTP-binding elongation factor signature 12 25 5.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 PRINTS PR00315 GTP-binding elongation factor signature 58 66 5.1E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS23930 b7d9f3693cc608696fd1db56ca0f76c0 698 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 697 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS13695 61f41addcdc40e865722a2006f7f2914 431 Pfam PF13660 Domain of unknown function (DUF4147) 28 237 8.4E-48 T 29-03-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 THSYN_RS13695 61f41addcdc40e865722a2006f7f2914 431 Gene3D G3DSA:3.40.1480.10 255 429 9.4E-41 T 29-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 THSYN_RS13695 61f41addcdc40e865722a2006f7f2914 431 Gene3D G3DSA:3.40.50.10180 29 240 1.2E-49 T 29-03-2018 THSYN_RS13695 61f41addcdc40e865722a2006f7f2914 431 SUPERFAMILY SSF82544 25 429 4.32E-95 T 29-03-2018 THSYN_RS13695 61f41addcdc40e865722a2006f7f2914 431 Pfam PF05161 MOFRL family 319 424 9.4E-30 T 29-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 THSYN_RS01890 ad92630f2ca04150bf04062f23b0a471 359 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 192 208 - T 29-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 THSYN_RS01890 ad92630f2ca04150bf04062f23b0a471 359 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 168 8.6E-17 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THSYN_RS01890 ad92630f2ca04150bf04062f23b0a471 359 SUPERFAMILY SSF55811 220 347 5.01E-22 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 THSYN_RS01890 ad92630f2ca04150bf04062f23b0a471 359 Gene3D G3DSA:1.10.1670.10 119 225 1.3E-35 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 THSYN_RS01890 ad92630f2ca04150bf04062f23b0a471 359 Pfam PF14815 NUDIX domain 236 345 1.5E-21 T 29-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 THSYN_RS01890 ad92630f2ca04150bf04062f23b0a471 359 Gene3D G3DSA:1.10.340.30 21 118 4.5E-34 T 29-03-2018 THSYN_RS01890 ad92630f2ca04150bf04062f23b0a471 359 SMART SM00478 39 190 3.6E-46 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THSYN_RS01890 ad92630f2ca04150bf04062f23b0a471 359 Gene3D G3DSA:3.90.79.10 230 350 9.8E-11 T 29-03-2018 THSYN_RS01890 ad92630f2ca04150bf04062f23b0a471 359 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 THSYN_RS01890 ad92630f2ca04150bf04062f23b0a471 359 SUPERFAMILY SSF48150 4 224 1.88E-75 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 THSYN_RS01890 ad92630f2ca04150bf04062f23b0a471 359 Pfam PF00633 Helix-hairpin-helix motif 99 127 1.6E-5 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 THSYN_RS01890 ad92630f2ca04150bf04062f23b0a471 359 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 6 266 3.6E-108 T 29-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 THSYN_RS09530 7b2ca7c8b7f3141b17e060b6248ae964 278 SUPERFAMILY SSF56436 1 228 2.33E-56 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS09530 7b2ca7c8b7f3141b17e060b6248ae964 278 Gene3D G3DSA:3.90.1580.10 56 240 2.2E-48 T 29-03-2018 THSYN_RS09530 7b2ca7c8b7f3141b17e060b6248ae964 278 Gene3D G3DSA:3.90.1580.10 1 55 3.2E-6 T 29-03-2018 THSYN_RS09530 7b2ca7c8b7f3141b17e060b6248ae964 278 Pfam PF03781 Sulfatase-modifying factor enzyme 1 3 228 3.7E-35 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 Gene3D G3DSA:2.60.260.20 253 363 8.2E-26 T 29-03-2018 THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 Pfam PF00684 DnaJ central domain 145 205 1.8E-14 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 SUPERFAMILY SSF49493 257 342 2.88E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 Pfam PF01556 DnaJ C terminal domain 119 331 1.3E-41 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 376 40.231 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 Gene3D G3DSA:1.10.287.110 1 115 2.2E-33 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 Gene3D G3DSA:2.60.260.20 192 252 3.3E-18 T 29-03-2018 THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 SUPERFAMILY SSF46565 1 111 4.06E-33 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 Gene3D G3DSA:2.10.230.10 145 191 3.1E-14 T 29-03-2018 THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 SUPERFAMILY SSF57938 132 209 1.57E-22 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 29-03-2018 IPR018253 DnaJ domain, conserved site THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 346 4.4E-132 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 SMART SM00271 4 62 3.8E-28 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 SUPERFAMILY SSF49493 211 265 8.24E-22 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 SUPERFAMILY SSF49493 111 136 8.24E-22 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 Pfam PF00226 DnaJ domain 5 67 9.1E-26 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 PRINTS PR00625 DnaJ domain signature 62 81 2.7E-28 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 PRINTS PR00625 DnaJ domain signature 42 62 2.7E-28 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 PRINTS PR00625 DnaJ domain signature 25 40 2.7E-28 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS26060 81fa8b11dae0e4424bf99664db6d01b6 376 PRINTS PR00625 DnaJ domain signature 7 25 2.7E-28 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS26160 ca0e1f4afa66b25fe159a03c76310cb0 155 Gene3D G3DSA:2.30.260.10 81 153 5.2E-18 T 29-03-2018 THSYN_RS26160 ca0e1f4afa66b25fe159a03c76310cb0 155 SUPERFAMILY SSF54001 31 153 2.88E-39 T 29-03-2018 THSYN_RS26160 ca0e1f4afa66b25fe159a03c76310cb0 155 Pfam PF00877 NlpC/P60 family 47 150 2.7E-26 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain THSYN_RS26160 ca0e1f4afa66b25fe159a03c76310cb0 155 Gene3D G3DSA:3.90.1720.10 30 80 5.5E-17 T 29-03-2018 THSYN_RS24005 9c12d0417460ed6b8b0f833b1808a3e5 119 Gene3D G3DSA:1.10.1900.20 55 116 9.0E-27 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24005 9c12d0417460ed6b8b0f833b1808a3e5 119 SUPERFAMILY SSF74731 2 117 2.35E-50 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24005 9c12d0417460ed6b8b0f833b1808a3e5 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 4.0E-21 T 29-03-2018 THSYN_RS24005 9c12d0417460ed6b8b0f833b1808a3e5 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.893 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24005 9c12d0417460ed6b8b0f833b1808a3e5 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 5.8E-40 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24005 9c12d0417460ed6b8b0f833b1808a3e5 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 5.8E-40 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24005 9c12d0417460ed6b8b0f833b1808a3e5 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 5.8E-40 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24005 9c12d0417460ed6b8b0f833b1808a3e5 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 5.7E-50 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24005 9c12d0417460ed6b8b0f833b1808a3e5 119 Pfam PF00453 Ribosomal protein L20 3 108 5.9E-49 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24005 9c12d0417460ed6b8b0f833b1808a3e5 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS19915 3f378601b81e7e10830c2d5c47428e32 110 Gene3D G3DSA:1.10.10.10 16 72 1.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19915 3f378601b81e7e10830c2d5c47428e32 110 SUPERFAMILY SSF46689 18 76 3.58E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS19915 3f378601b81e7e10830c2d5c47428e32 110 Pfam PF04255 Protein of unknown function (DUF433) 18 64 7.6E-10 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 SMART SM00267 266 434 3.6E-55 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 Pfam PF00072 Response regulator receiver domain 14 120 3.9E-11 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 Gene3D G3DSA:3.30.70.270 271 434 1.1E-49 T 29-03-2018 THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 Gene3D G3DSA:3.40.50.2300 7 114 2.3E-17 T 29-03-2018 THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 Pfam PF00990 Diguanylate cyclase, GGDEF domain 277 430 3.8E-41 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 SMART SM00086 223 266 3.6E-7 T 29-03-2018 IPR001610 PAC motif THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 Gene3D G3DSA:3.30.450.20 115 270 2.4E-34 T 29-03-2018 THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 274 433 4.8E-46 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 SUPERFAMILY SSF55785 136 264 5.93E-21 T 29-03-2018 IPR000014 PAS domain THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 SMART SM00448 11 123 5.6E-6 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 SMART SM00091 148 216 0.0012 T 29-03-2018 IPR000014 PAS domain THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 273 1.7E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 SUPERFAMILY SSF55073 282 432 2.43E-42 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 SUPERFAMILY SSF52172 11 163 9.11E-23 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS25880 6ec66bb063823e16981b97bf28c3981b 436 Pfam PF08447 PAS fold 172 260 3.4E-21 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 PRINTS PR00992 Alanine racemase signature 193 220 1.0E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 PRINTS PR00992 Alanine racemase signature 156 167 1.0E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 PRINTS PR00992 Alanine racemase signature 267 282 1.0E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 PRINTS PR00992 Alanine racemase signature 250 265 1.0E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 PRINTS PR00992 Alanine racemase signature 122 134 1.0E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 PRINTS PR00992 Alanine racemase signature 288 305 1.0E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 PRINTS PR00992 Alanine racemase signature 340 353 1.0E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 PRINTS PR00992 Alanine racemase signature 62 80 1.0E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 PRINTS PR00992 Alanine racemase signature 27 43 1.0E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 TIGRFAM TIGR00492 alr: alanine racemase 4 357 3.6E-107 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 SMART SM01005 234 358 1.4E-60 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 Pfam PF00842 Alanine racemase, C-terminal domain 234 357 1.2E-38 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 Gene3D G3DSA:2.40.37.10 219 366 6.6E-52 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 Hamap MF_01201 Alanine racemase. 2 358 33.898 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 SUPERFAMILY SSF50621 229 358 1.71E-42 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 Pfam PF01168 Alanine racemase, N-terminal domain 9 220 1.0E-70 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 32 42 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 Gene3D G3DSA:3.20.20.10 1 218 4.8E-47 T 29-03-2018 IPR029066 PLP-binding barrel THSYN_RS16620 dc5517f0e8ca3756bd67f70a33bca433 370 SUPERFAMILY SSF51419 9 235 1.02E-70 T 29-03-2018 IPR029066 PLP-binding barrel THSYN_RS27525 0e8b3993299bff08789c5cad97df9161 535 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 54 518 220.193 T 29-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 THSYN_RS27525 0e8b3993299bff08789c5cad97df9161 535 Pfam PF12390 Selenocysteine synthase N terminal 54 92 3.9E-9 T 29-03-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 THSYN_RS27525 0e8b3993299bff08789c5cad97df9161 535 SUPERFAMILY SSF53383 124 396 1.16E-44 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS27525 0e8b3993299bff08789c5cad97df9161 535 Gene3D G3DSA:3.40.640.10 145 403 5.3E-32 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS27525 0e8b3993299bff08789c5cad97df9161 535 Pfam PF03841 L-seryl-tRNA selenium transferase 133 502 4.9E-156 T 29-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 THSYN_RS27525 0e8b3993299bff08789c5cad97df9161 535 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 54 506 4.3E-167 T 29-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 THSYN_RS20175 0a2e42c1a17bf8067678ba83aaada0e2 408 Gene3D G3DSA:2.40.50.100 36 82 6.0E-4 T 29-03-2018 THSYN_RS20175 0a2e42c1a17bf8067678ba83aaada0e2 408 Pfam PF13437 HlyD family secretion protein 203 295 6.3E-8 T 29-03-2018 THSYN_RS20175 0a2e42c1a17bf8067678ba83aaada0e2 408 Gene3D G3DSA:2.40.50.100 83 231 1.8E-10 T 29-03-2018 THSYN_RS20175 0a2e42c1a17bf8067678ba83aaada0e2 408 Pfam PF13533 Biotin-lipoyl like 68 111 2.3E-8 T 29-03-2018 THSYN_RS20175 0a2e42c1a17bf8067678ba83aaada0e2 408 SUPERFAMILY SSF111369 53 266 3.92E-14 T 29-03-2018 THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 SMART SM00671 87 122 8.9E-4 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 SMART SM00671 195 230 4.6E-7 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 SMART SM00671 159 194 2.6E-5 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 SMART SM00671 123 158 0.52 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 SMART SM00671 51 86 0.0021 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 SUPERFAMILY SSF81901 27 244 2.18E-38 T 29-03-2018 THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 Pfam PF08238 Sel1 repeat 52 85 9.7E-4 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 Pfam PF08238 Sel1 repeat 159 194 7.1E-5 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 Pfam PF08238 Sel1 repeat 129 156 0.0043 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 Pfam PF08238 Sel1 repeat 87 121 0.42 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 Pfam PF08238 Sel1 repeat 195 229 5.4E-8 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 Gene3D G3DSA:2.60.40.1180 26 115 1.9E-15 T 29-03-2018 THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 Gene3D G3DSA:2.60.40.1180 116 186 1.4E-16 T 29-03-2018 THSYN_RS00180 a7dd7539c376125a5871653c95f05ddf 322 Gene3D G3DSA:2.60.40.1180 187 290 5.9E-12 T 29-03-2018 THSYN_RS16510 8f7631721fa0656891109c3376faaf25 677 TIGRFAM TIGR02061 aprA: adenylylsulfate reductase, alpha subunit 17 666 1.5E-277 T 29-03-2018 IPR011803 Adenylylsulphate reductase, alpha subunit KEGG: 00920+1.8.99.2|MetaCyc: PWY-5278|MetaCyc: PWY-5279 THSYN_RS16510 8f7631721fa0656891109c3376faaf25 677 SUPERFAMILY SSF56425 271 416 5.75E-66 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS16510 8f7631721fa0656891109c3376faaf25 677 Gene3D G3DSA:3.90.700.10 290 408 1.8E-57 T 29-03-2018 THSYN_RS16510 8f7631721fa0656891109c3376faaf25 677 PIRSF PIRSF000171 6 671 5.0E-253 T 29-03-2018 THSYN_RS16510 8f7631721fa0656891109c3376faaf25 677 SUPERFAMILY SSF51905 447 524 5.14E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS16510 8f7631721fa0656891109c3376faaf25 677 SUPERFAMILY SSF51905 10 289 5.14E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS16510 8f7631721fa0656891109c3376faaf25 677 SUPERFAMILY SSF46977 533 666 1.83E-38 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS16510 8f7631721fa0656891109c3376faaf25 677 Pfam PF00890 FAD binding domain 17 278 3.2E-9 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS16510 8f7631721fa0656891109c3376faaf25 677 Gene3D G3DSA:1.20.58.100 505 633 1.9E-17 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS16510 8f7631721fa0656891109c3376faaf25 677 Gene3D G3DSA:3.50.50.60 12 289 9.0E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 Gene3D G3DSA:3.10.290.10 325 401 4.8E-18 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 4 401 48.538 T 29-03-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 SUPERFAMILY SSF52374 8 318 4.61E-94 T 29-03-2018 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 Pfam PF00579 tRNA synthetases class I (W and Y) 35 319 1.2E-74 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 6 401 1.0E-115 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 Gene3D G3DSA:1.10.240.10 221 322 1.9E-23 T 29-03-2018 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 SUPERFAMILY SSF55174 326 401 5.5E-18 T 29-03-2018 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 48 70 6.0E-26 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 213 225 6.0E-26 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 163 178 6.0E-26 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 180 202 6.0E-26 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 44 54 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 SMART SM00363 340 402 0.0017 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 Gene3D G3DSA:3.40.50.620 3 220 3.4E-63 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS03900 fa5cc180e622751c13d7057c99cb23c0 409 Pfam PF01479 S4 domain 342 384 7.5E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS15465 43d34f92d714e8a6afe5e9d27f3e47b7 220 Gene3D G3DSA:2.40.50.260 11 120 1.7E-24 T 29-03-2018 THSYN_RS15465 43d34f92d714e8a6afe5e9d27f3e47b7 220 SUPERFAMILY SSF69349 86 180 3.37E-6 T 29-03-2018 THSYN_RS15465 43d34f92d714e8a6afe5e9d27f3e47b7 220 SUPERFAMILY SSF69255 12 92 2.59E-17 T 29-03-2018 THSYN_RS16690 23f1a7f55c4998e72300ea460b0d0cfb 179 PIRSF PIRSF011484 1 178 8.9E-72 T 29-03-2018 IPR009822 YaeQ THSYN_RS16690 23f1a7f55c4998e72300ea460b0d0cfb 179 SUPERFAMILY SSF52980 4 175 7.78E-72 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS16690 23f1a7f55c4998e72300ea460b0d0cfb 179 SMART SM01322 1 176 3.7E-117 T 29-03-2018 IPR009822 YaeQ THSYN_RS16690 23f1a7f55c4998e72300ea460b0d0cfb 179 Gene3D G3DSA:3.10.640.10 2 177 6.5E-82 T 29-03-2018 THSYN_RS16690 23f1a7f55c4998e72300ea460b0d0cfb 179 Pfam PF07152 YaeQ protein 1 173 5.0E-78 T 29-03-2018 IPR009822 YaeQ THSYN_RS06345 cc4aa7af109c33a2f2e6b87301c57461 220 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 217 3.6E-76 T 29-03-2018 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 THSYN_RS06345 cc4aa7af109c33a2f2e6b87301c57461 220 SUPERFAMILY SSF53335 1 217 7.97E-59 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS06345 cc4aa7af109c33a2f2e6b87301c57461 220 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 217 39.781 T 29-03-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 THSYN_RS06345 cc4aa7af109c33a2f2e6b87301c57461 220 Gene3D G3DSA:3.40.50.150 16 218 3.5E-28 T 29-03-2018 THSYN_RS06345 cc4aa7af109c33a2f2e6b87301c57461 220 PIRSF PIRSF023956 1 219 5.1E-79 T 29-03-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 THSYN_RS06345 cc4aa7af109c33a2f2e6b87301c57461 220 TIGRFAM TIGR03840 TMPT_Se_Te: thiopurine S-methyltransferase, Se/Te detoxification family 4 215 1.3E-82 T 29-03-2018 IPR022474 Thiopurine S-methyltransferase, Se/Te detoxification GO:0008119|GO:0010038|GO:0032259 KEGG: 00983+2.1.1.67 THSYN_RS28090 da4a461b46896cf49bd0cd05045edbef 599 Pfam PF00474 Sodium:solute symporter family 34 300 1.0E-32 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THSYN_RS28090 da4a461b46896cf49bd0cd05045edbef 599 Pfam PF00474 Sodium:solute symporter family 394 513 2.5E-14 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THSYN_RS28090 da4a461b46896cf49bd0cd05045edbef 599 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 9 588 5.2E-231 T 29-03-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Gene3D G3DSA:1.10.10.670 917 959 1.1E-5 T 29-03-2018 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 822 836 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1253 1267 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Pfam PF12770 CHAT domain 27 193 8.4E-10 T 29-03-2018 IPR024983 CHAT domain THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Gene3D G3DSA:2.130.10.10 764 916 9.9E-34 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SUPERFAMILY SSF50998 800 1096 7.45E-62 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Gene3D G3DSA:2.120.10.30 1399 1517 9.7E-17 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SUPERFAMILY SSF52540 255 490 1.9E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 PRINTS PR00320 G protein beta WD-40 repeat signature 1296 1310 1.4E-5 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 PRINTS PR00320 G protein beta WD-40 repeat signature 1036 1050 1.4E-5 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 PRINTS PR00320 G protein beta WD-40 repeat signature 1079 1093 1.4E-5 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SUPERFAMILY SSF50978 1185 1498 1.83E-48 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SUPERFAMILY SSF50978 1015 1270 2.75E-49 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Pfam PF00400 WD domain, G-beta repeat 1276 1309 9.9E-8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Pfam PF00400 WD domain, G-beta repeat 846 876 0.0015 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Pfam PF00400 WD domain, G-beta repeat 972 1006 1.1E-6 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Pfam PF00400 WD domain, G-beta repeat 1453 1477 0.0075 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Pfam PF00400 WD domain, G-beta repeat 1058 1092 2.5E-6 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Pfam PF00400 WD domain, G-beta repeat 1110 1135 0.051 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Pfam PF00400 WD domain, G-beta repeat 1144 1178 0.0037 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Pfam PF00400 WD domain, G-beta repeat 1015 1049 7.4E-7 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Pfam PF00400 WD domain, G-beta repeat 805 835 0.0013 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Pfam PF00400 WD domain, G-beta repeat 1405 1435 0.21 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Gene3D G3DSA:2.140.10.30 1065 1169 1.5E-27 T 29-03-2018 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 1398 1435 2.2 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 839 878 1.4E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 1010 1049 5.4E-8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 1225 1266 31.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 925 963 41.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 1096 1135 0.52 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 1313 1352 1.5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 1270 1309 8.1E-8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 883 921 1.8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 1182 1221 28.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 797 835 9.2E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 1439 1478 0.015 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 748 792 110.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 1139 1178 0.69 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 1053 1092 8.3E-7 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 1356 1395 0.96 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 SMART SM00320 967 1006 7.3E-8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Gene3D G3DSA:3.40.50.1460 6 208 1.2E-13 T 29-03-2018 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 779 793 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Gene3D G3DSA:2.130.10.120 1269 1371 2.1E-24 T 29-03-2018 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Gene3D G3DSA:3.40.50.300 243 393 5.3E-7 T 29-03-2018 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 908 922 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 993 1007 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Gene3D G3DSA:2.80.10.50 1372 1398 2.9E-4 T 29-03-2018 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1296 1310 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Gene3D G3DSA:2.140.10.30 1170 1268 1.1E-12 T 29-03-2018 THSYN_RS13875 0fc8c4de96abae243e832a5e5427e45f 1532 Gene3D G3DSA:2.130.10.10 960 1064 2.5E-28 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS04635 d2a8658a974e2658764165a7bfc768a1 105 Pfam PF01909 Nucleotidyltransferase domain 22 88 7.4E-8 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS04635 d2a8658a974e2658764165a7bfc768a1 105 SUPERFAMILY SSF81301 4 103 2.77E-11 T 29-03-2018 THSYN_RS04635 d2a8658a974e2658764165a7bfc768a1 105 Gene3D G3DSA:3.30.460.10 1 105 1.9E-12 T 29-03-2018 THSYN_RS03570 d485f744daaf831b50b49659b46e1658 312 SUPERFAMILY SSF56059 107 305 4.42E-56 T 29-03-2018 THSYN_RS03570 d485f744daaf831b50b49659b46e1658 312 PIRSF PIRSF039102 12 57 1.9E-6 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03570 d485f744daaf831b50b49659b46e1658 312 PIRSF PIRSF039102 51 312 6.5E-79 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03570 d485f744daaf831b50b49659b46e1658 312 SUPERFAMILY SSF52440 15 107 8.92E-28 T 29-03-2018 IPR016185 Pre-ATP-grasp domain THSYN_RS03570 d485f744daaf831b50b49659b46e1658 312 Gene3D G3DSA:3.30.1490.20 110 175 1.1E-17 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS03570 d485f744daaf831b50b49659b46e1658 312 Gene3D G3DSA:3.30.470.20 176 312 4.4E-38 T 29-03-2018 THSYN_RS03570 d485f744daaf831b50b49659b46e1658 312 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 74 85 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03570 d485f744daaf831b50b49659b46e1658 312 Pfam PF01820 D-ala D-ala ligase N-terminus 15 97 1.7E-15 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03570 d485f744daaf831b50b49659b46e1658 312 Gene3D G3DSA:3.40.50.20 5 109 1.4E-29 T 29-03-2018 THSYN_RS03570 d485f744daaf831b50b49659b46e1658 312 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 15 308 3.0E-97 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03570 d485f744daaf831b50b49659b46e1658 312 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 251 279 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03570 d485f744daaf831b50b49659b46e1658 312 Pfam PF07478 D-ala D-ala ligase C-terminus 123 306 3.4E-53 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03570 d485f744daaf831b50b49659b46e1658 312 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 14 309 34.36 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS32185 b4918fd25c7b648d4692feea0b8c4dfc 227 SUPERFAMILY SSF63965 12 219 5.76E-64 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 THSYN_RS32185 b4918fd25c7b648d4692feea0b8c4dfc 227 Pfam PF02570 Precorrin-8X methylmutase 20 217 4.8E-71 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 THSYN_RS32185 b4918fd25c7b648d4692feea0b8c4dfc 227 Gene3D G3DSA:3.40.50.10230 13 225 1.0E-75 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 THSYN_RS27785 c2ede263df14150128bc703b35bec9a9 149 Pfam PF01475 Ferric uptake regulator family 18 131 2.5E-12 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 THSYN_RS27785 c2ede263df14150128bc703b35bec9a9 149 SUPERFAMILY SSF46785 12 143 5.51E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS27785 c2ede263df14150128bc703b35bec9a9 149 Gene3D G3DSA:1.10.10.10 2 89 1.4E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS23370 06e416624f2328718013989dc645a703 523 Pfam PF04262 Glutamate-cysteine ligase 9 376 2.8E-151 T 29-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 THSYN_RS23370 06e416624f2328718013989dc645a703 523 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 523 185.162 T 29-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 THSYN_RS23370 06e416624f2328718013989dc645a703 523 SUPERFAMILY SSF55931 11 513 3.14E-170 T 29-03-2018 THSYN_RS23370 06e416624f2328718013989dc645a703 523 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 14 515 1.1E-157 T 29-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 THSYN_RS21850 0757d38ae39c5a46280d3f515e49d5a5 425 PIRSF PIRSF005353 1 425 5.0E-160 T 29-03-2018 IPR026033 Purine permease PbuG-like THSYN_RS21850 0757d38ae39c5a46280d3f515e49d5a5 425 Pfam PF00860 Permease family 14 387 4.5E-50 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Gene3D G3DSA:2.60.120.640 294 368 1.7E-6 T 29-03-2018 THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Gene3D G3DSA:2.60.40.10 369 465 1.9E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF05593 RHS Repeat 1235 1272 1.1E-7 T 29-03-2018 IPR031325 RHS repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF05593 RHS Repeat 1670 1703 2.6E-5 T 29-03-2018 IPR031325 RHS repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF05593 RHS Repeat 1609 1644 7.9E-8 T 29-03-2018 IPR031325 RHS repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF05593 RHS Repeat 1434 1459 7.3E-5 T 29-03-2018 IPR031325 RHS repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF05593 RHS Repeat 1509 1545 1.0E-8 T 29-03-2018 IPR031325 RHS repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF05593 RHS Repeat 1630 1666 7.2E-9 T 29-03-2018 IPR031325 RHS repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF05593 RHS Repeat 1109 1142 1.4E-8 T 29-03-2018 IPR031325 RHS repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF05593 RHS Repeat 1193 1226 2.6E-8 T 29-03-2018 IPR031325 RHS repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF05593 RHS Repeat 1343 1379 9.8E-6 T 29-03-2018 IPR031325 RHS repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF05593 RHS Repeat 1467 1503 9.8E-7 T 29-03-2018 IPR031325 RHS repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF05593 RHS Repeat 1308 1337 1.3E-5 T 29-03-2018 IPR031325 RHS repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF05593 RHS Repeat 1214 1249 1.3E-8 T 29-03-2018 IPR031325 RHS repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Gene3D G3DSA:2.120.10.30 1409 1661 0.16 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Gene3D G3DSA:2.120.10.30 845 1197 1.7E-5 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1944 2022 1.9E-15 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 SUPERFAMILY SSF69318 26 263 3.4E-24 T 29-03-2018 THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Gene3D G3DSA:2.120.10.30 1198 1408 1.6E-6 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Gene3D G3DSA:2.60.40.1080 607 694 7.1E-11 T 29-03-2018 THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 30 92 7.7E-7 T 29-03-2018 THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 SUPERFAMILY SSF82171 1156 1400 1.29E-8 T 29-03-2018 THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Gene3D G3DSA:2.130.10.130 3 127 5.7E-7 T 29-03-2018 THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Gene3D G3DSA:2.130.10.130 128 261 3.2E-11 T 29-03-2018 THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 SUPERFAMILY SSF63829 1016 1224 1.5E-6 T 29-03-2018 THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 SMART SM00740 533 601 7.2E-4 T 29-03-2018 IPR005543 PASTA domain THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 SMART SM00740 465 532 4.0E-7 T 29-03-2018 IPR005543 PASTA domain THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Gene3D G3DSA:2.60.40.650 700 810 6.4E-5 T 29-03-2018 THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 Pfam PF03793 PASTA domain 469 532 1.9E-6 T 29-03-2018 IPR005543 PASTA domain THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1826 1857 0.0017 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1343 1382 9.5E-8 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1530 1570 7.7E-4 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1371 1405 0.0015 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1609 1648 1.8E-6 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1446 1486 6.8E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1004 1044 1.8E-8 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1256 1297 9.4E-8 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1650 1678 4.4E-6 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1214 1253 5.4E-10 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1488 1527 3.4E-9 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1432 1460 2.1E-4 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1173 1213 7.2E-7 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1097 1129 6.7E-6 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1307 1336 8.0E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS10205 4599a21dbbb169a420d1ccad32b2904e 2197 SUPERFAMILY SSF49373 626 692 5.96E-5 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments THSYN_RS06395 eb953c463d1369c6816dcb06086075b1 800 Gene3D G3DSA:3.40.50.300 169 337 1.9E-18 T 29-03-2018 THSYN_RS06395 eb953c463d1369c6816dcb06086075b1 800 Pfam PF00271 Helicase conserved C-terminal domain 433 544 7.7E-8 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS06395 eb953c463d1369c6816dcb06086075b1 800 SUPERFAMILY SSF52540 410 553 1.03E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06395 eb953c463d1369c6816dcb06086075b1 800 SUPERFAMILY SSF52540 191 327 1.03E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06395 eb953c463d1369c6816dcb06086075b1 800 Pfam PF08463 EcoEI R protein C-terminal 681 794 5.1E-6 T 29-03-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 THSYN_RS06395 eb953c463d1369c6816dcb06086075b1 800 Pfam PF04851 Type III restriction enzyme, res subunit 175 325 4.2E-21 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS06395 eb953c463d1369c6816dcb06086075b1 800 Gene3D G3DSA:3.40.50.300 415 558 1.7E-13 T 29-03-2018 THSYN_RS06395 eb953c463d1369c6816dcb06086075b1 800 SMART SM00487 171 365 1.0E-12 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 SUPERFAMILY SSF141868 549 798 4.97E-83 T 29-03-2018 IPR001633 EAL domain THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 SUPERFAMILY SSF55785 146 260 6.0E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 Pfam PF00989 PAS fold 266 337 2.0E-5 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 Pfam PF13426 PAS domain 146 251 4.5E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 SUPERFAMILY SSF55785 276 371 2.09E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 Gene3D G3DSA:3.30.70.270 374 535 1.5E-58 T 29-03-2018 THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 Gene3D G3DSA:3.30.450.20 127 241 7.7E-21 T 29-03-2018 THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 Gene3D G3DSA:3.20.20.450 536 804 7.2E-95 T 29-03-2018 IPR001633 EAL domain THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 370 534 2.3E-42 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 Pfam PF00563 EAL domain 550 785 1.9E-71 T 29-03-2018 IPR001633 EAL domain THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 Pfam PF00990 Diguanylate cyclase, GGDEF domain 374 529 1.0E-47 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 SMART SM00267 362 534 1.2E-64 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 Gene3D G3DSA:3.30.450.20 242 373 5.1E-16 T 29-03-2018 THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 SMART SM00086 212 252 10.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 SMART SM00086 322 362 0.044 T 29-03-2018 IPR001610 PAC motif THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 SMART SM00091 135 202 5.5E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 SMART SM00091 264 330 0.013 T 29-03-2018 IPR000014 PAS domain THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 SUPERFAMILY SSF55073 378 536 1.52E-49 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 136 258 3.3E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS14220 a2c5baf25d557140e571facd63de9103 850 SMART SM00052 544 790 1.6E-102 T 29-03-2018 IPR001633 EAL domain THSYN_RS00575 86c0288a1b1b97d2375335ec170b7b5f 406 Pfam PF00072 Response regulator receiver domain 4 84 2.2E-9 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00575 86c0288a1b1b97d2375335ec170b7b5f 406 SUPERFAMILY SSF141868 151 392 3.01E-68 T 29-03-2018 IPR001633 EAL domain THSYN_RS00575 86c0288a1b1b97d2375335ec170b7b5f 406 Pfam PF00563 EAL domain 153 383 1.9E-58 T 29-03-2018 IPR001633 EAL domain THSYN_RS00575 86c0288a1b1b97d2375335ec170b7b5f 406 Gene3D G3DSA:3.40.50.2300 1 119 7.4E-11 T 29-03-2018 THSYN_RS00575 86c0288a1b1b97d2375335ec170b7b5f 406 SUPERFAMILY SSF52172 2 87 7.12E-11 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS00575 86c0288a1b1b97d2375335ec170b7b5f 406 SMART SM00052 145 388 5.1E-68 T 29-03-2018 IPR001633 EAL domain THSYN_RS00575 86c0288a1b1b97d2375335ec170b7b5f 406 Gene3D G3DSA:3.20.20.450 145 396 6.1E-70 T 29-03-2018 IPR001633 EAL domain THSYN_RS31650 eedafda533ae95459db784a78f884a5d 280 Pfam PF12291 Protein of unknown function (DUF3623) 1 254 8.8E-106 T 29-03-2018 IPR017496 Photosynthetic complex assembly protein 2, putative THSYN_RS31650 eedafda533ae95459db784a78f884a5d 280 TIGRFAM TIGR03055 photo_alph_chp2: putative photosynthetic complex assembly protein 2 6 248 3.5E-91 T 29-03-2018 IPR017496 Photosynthetic complex assembly protein 2, putative THSYN_RS04165 e4ad7ec549a5ce28e0ef53f6e1f4dbc8 481 Gene3D G3DSA:3.40.50.620 1 305 4.3E-89 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS04165 e4ad7ec549a5ce28e0ef53f6e1f4dbc8 481 SMART SM00840 340 401 2.6E-26 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 THSYN_RS04165 e4ad7ec549a5ce28e0ef53f6e1f4dbc8 481 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 480 3.4E-168 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 THSYN_RS04165 e4ad7ec549a5ce28e0ef53f6e1f4dbc8 481 SUPERFAMILY SSF47323 316 480 2.75E-34 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS04165 e4ad7ec549a5ce28e0ef53f6e1f4dbc8 481 SUPERFAMILY SSF52374 2 313 6.91E-99 T 29-03-2018 THSYN_RS04165 e4ad7ec549a5ce28e0ef53f6e1f4dbc8 481 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 480 38.882 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 THSYN_RS04165 e4ad7ec549a5ce28e0ef53f6e1f4dbc8 481 Gene3D G3DSA:1.20.120.640 306 393 5.6E-21 T 29-03-2018 THSYN_RS04165 e4ad7ec549a5ce28e0ef53f6e1f4dbc8 481 Pfam PF09190 DALR domain 340 401 1.1E-21 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 THSYN_RS04165 e4ad7ec549a5ce28e0ef53f6e1f4dbc8 481 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 3.3E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THSYN_RS04165 e4ad7ec549a5ce28e0ef53f6e1f4dbc8 481 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 3.3E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THSYN_RS04165 e4ad7ec549a5ce28e0ef53f6e1f4dbc8 481 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 3.3E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THSYN_RS04165 e4ad7ec549a5ce28e0ef53f6e1f4dbc8 481 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 3.3E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THSYN_RS04165 e4ad7ec549a5ce28e0ef53f6e1f4dbc8 481 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 313 6.1E-130 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Gene3D G3DSA:3.30.450.20 749 893 3.2E-39 T 29-03-2018 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Gene3D G3DSA:3.30.450.20 625 748 2.4E-37 T 29-03-2018 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SUPERFAMILY SSF158472 407 455 4.58E-5 T 29-03-2018 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SMART SM00448 1152 1267 1.1E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1007 1121 2.7E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Gene3D G3DSA:3.30.450.20 235 380 1.3E-9 T 29-03-2018 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Pfam PF08447 PAS fold 657 740 1.2E-13 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Pfam PF08447 PAS fold 528 599 1.4E-6 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SUPERFAMILY SSF47226 1309 1407 2.09E-9 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Gene3D G3DSA:1.20.5.50 422 497 0.0057 T 29-03-2018 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Gene3D G3DSA:3.30.565.10 964 1130 9.6E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Pfam PF00989 PAS fold 761 872 2.1E-12 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SUPERFAMILY SSF47384 880 961 5.69E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Gene3D G3DSA:3.30.450.20 109 234 6.8E-4 T 29-03-2018 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Gene3D G3DSA:1.20.120.160 1301 1467 2.3E-8 T 29-03-2018 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SMART SM00086 585 621 2.6 T 29-03-2018 IPR001610 PAC motif THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SMART SM00086 706 748 1.1E-5 T 29-03-2018 IPR001610 PAC motif THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SMART SM00086 833 875 4.2E-9 T 29-03-2018 IPR001610 PAC motif THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SMART SM00388 895 960 3.6E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SUPERFAMILY SSF52172 1152 1277 3.56E-34 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SMART SM00387 1007 1123 5.5E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1066 1076 2.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1083 1101 2.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1107 1120 2.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1048 1062 2.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SMART SM00304 405 457 1.4E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SUPERFAMILY SSF55785 745 873 1.77E-27 T 29-03-2018 IPR000014 PAS domain THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 756 882 5.7E-31 T 29-03-2018 IPR000014 PAS domain THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 629 755 2.9E-27 T 29-03-2018 IPR000014 PAS domain THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Pfam PF00672 HAMP domain 407 453 2.3E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Gene3D G3DSA:3.30.450.20 498 624 3.2E-21 T 29-03-2018 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SUPERFAMILY SSF55785 618 746 6.12E-29 T 29-03-2018 IPR000014 PAS domain THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Gene3D G3DSA:3.40.50.2300 1141 1279 3.4E-35 T 29-03-2018 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Pfam PF00512 His Kinase A (phospho-acceptor) domain 895 959 3.3E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SUPERFAMILY SSF55874 949 1121 1.96E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SMART SM00091 503 571 2.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SMART SM00091 760 826 2.5E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SMART SM00091 633 699 4.1E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Pfam PF00072 Response regulator receiver domain 1155 1266 2.1E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 SUPERFAMILY SSF55785 520 630 2.44E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS09825 d773c02f0967fcc25403c453f00c2b0a 1507 Gene3D G3DSA:1.10.287.130 894 956 7.6E-19 T 29-03-2018 THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 563 581 2.5E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 587 600 2.5E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 556 2.5E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 542 2.5E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 SUPERFAMILY SSF47384 360 441 1.94E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 Gene3D G3DSA:1.10.287.130 379 436 2.6E-19 T 29-03-2018 THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 SUPERFAMILY SSF52172 618 736 7.97E-5 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 Gene3D G3DSA:3.40.50.2300 766 912 1.3E-42 T 29-03-2018 THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 SUPERFAMILY SSF52172 777 905 3.27E-36 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 Gene3D G3DSA:3.30.565.10 444 609 9.7E-49 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 SMART SM00388 375 440 1.3E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 Gene3D G3DSA:3.30.450.20 149 378 2.4E-6 T 29-03-2018 THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 SMART SM00448 778 900 3.3E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 SUPERFAMILY SSF55874 429 603 8.38E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 Pfam PF00072 Response regulator receiver domain 780 900 2.4E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 SMART SM00387 487 603 5.7E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 Gene3D G3DSA:3.40.50.2300 614 739 4.5E-4 T 29-03-2018 THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 488 601 3.3E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS11115 6cccd4baa4f159ff1be47cbaddb2f1b2 917 Pfam PF00512 His Kinase A (phospho-acceptor) domain 375 440 4.8E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 SUPERFAMILY SSF55785 364 486 1.03E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 Gene3D G3DSA:3.30.565.10 564 732 7.4E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 SMART SM00304 307 360 2.6E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 607 730 1.1E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 SUPERFAMILY SSF47384 491 566 2.75E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 PIRSF PIRSF037532 2 734 2.3E-207 T 29-03-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 PRINTS PR00344 Bacterial sensor protein C-terminal signature 717 730 3.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 PRINTS PR00344 Bacterial sensor protein C-terminal signature 683 693 3.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 PRINTS PR00344 Bacterial sensor protein C-terminal signature 665 679 3.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 PRINTS PR00344 Bacterial sensor protein C-terminal signature 694 712 3.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 Gene3D G3DSA:3.30.450.20 121 243 2.5E-6 T 29-03-2018 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 Pfam PF00512 His Kinase A (phospho-acceptor) domain 497 564 3.8E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 Pfam PF00672 HAMP domain 307 356 2.1E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 SMART SM00387 607 733 7.9E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 SMART SM00388 496 568 3.7E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 Gene3D G3DSA:3.30.450.20 353 491 4.5E-16 T 29-03-2018 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 Gene3D G3DSA:1.10.287.130 492 563 3.2E-11 T 29-03-2018 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 SUPERFAMILY SSF158472 307 357 2.22E-8 T 29-03-2018 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 Pfam PF08448 PAS fold 382 487 5.2E-5 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS20620 75fd7630a7caae5af5ddbd9785eaf479 749 SUPERFAMILY SSF55874 557 731 1.7E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 SUPERFAMILY SSF55424 361 484 1.72E-38 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 365 473 5.4E-33 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 Gene3D G3DSA:3.40.50.720 193 352 5.1E-31 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 Gene3D G3DSA:3.30.390.30 353 482 1.0E-36 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 27 479 2.8E-147 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 27 346 1.3E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 61 71 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 426 441 5.0E-73 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 196 221 5.0E-73 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 27 49 5.0E-73 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 169 5.0E-73 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 448 468 5.0E-73 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 283 297 5.0E-73 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 361 382 5.0E-73 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 60 75 5.0E-73 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 326 333 5.0E-73 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 Gene3D G3DSA:3.50.50.60 25 192 3.6E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 8.8E-40 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 298 8.8E-40 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 196 214 8.8E-40 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 28 47 8.8E-40 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 311 333 8.8E-40 T 29-03-2018 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 SUPERFAMILY SSF51905 27 399 2.53E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS19380 c3cdb0466be8f495af2715881737d27a 490 PIRSF PIRSF000350 4 485 1.2E-87 T 29-03-2018 THSYN_RS22010 2df69179651a4eacd2ce2b4c9ec28b46 395 Gene3D G3DSA:1.10.1740.10 308 391 8.1E-26 T 29-03-2018 THSYN_RS22010 2df69179651a4eacd2ce2b4c9ec28b46 395 Pfam PF13288 DXP reductoisomerase C-terminal domain 266 384 7.8E-39 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 THSYN_RS22010 2df69179651a4eacd2ce2b4c9ec28b46 395 PIRSF PIRSF006205 1 394 1.9E-147 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 THSYN_RS22010 2df69179651a4eacd2ce2b4c9ec28b46 395 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 5.6E-44 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 THSYN_RS22010 2df69179651a4eacd2ce2b4c9ec28b46 395 Gene3D G3DSA:3.40.50.720 2 150 1.4E-48 T 29-03-2018 THSYN_RS22010 2df69179651a4eacd2ce2b4c9ec28b46 395 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 388 1.9E-147 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 THSYN_RS22010 2df69179651a4eacd2ce2b4c9ec28b46 395 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 234 1.2E-38 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 THSYN_RS22010 2df69179651a4eacd2ce2b4c9ec28b46 395 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 389 46.534 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 THSYN_RS22010 2df69179651a4eacd2ce2b4c9ec28b46 395 SUPERFAMILY SSF69055 297 390 7.85E-26 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 THSYN_RS22010 2df69179651a4eacd2ce2b4c9ec28b46 395 SUPERFAMILY SSF55347 126 269 5.89E-60 T 29-03-2018 THSYN_RS22010 2df69179651a4eacd2ce2b4c9ec28b46 395 SUPERFAMILY SSF51735 3 150 7.73E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS11195 6018421122e8ecbe2fb962d2919b427f 179 Pfam PF05069 Phage virion morphogenesis family 11 70 6.7E-12 T 29-03-2018 IPR006522 Phage virion morphogensis protein THSYN_RS11195 6018421122e8ecbe2fb962d2919b427f 179 Pfam PF05069 Phage virion morphogenesis family 98 175 2.6E-11 T 29-03-2018 IPR006522 Phage virion morphogensis protein THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 247 273 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 Gene3D G3DSA:1.10.10.10 219 278 1.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 SUPERFAMILY SSF88659 185 277 1.79E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 1 279 48.226 T 29-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 Pfam PF04545 Sigma-70, region 4 224 274 1.2E-14 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 11 277 6.2E-119 T 29-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 74 87 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 Pfam PF04542 Sigma-70 region 2 51 119 2.1E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 SUPERFAMILY SSF88946 9 119 3.66E-39 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 Gene3D G3DSA:1.10.601.10 9 119 7.1E-33 T 29-03-2018 THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 PRINTS PR00046 Major sigma-70 factor signature 74 87 3.2E-18 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 PRINTS PR00046 Major sigma-70 factor signature 228 240 3.2E-18 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 PRINTS PR00046 Major sigma-70 factor signature 247 262 3.2E-18 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 PRINTS PR00046 Major sigma-70 factor signature 262 273 3.2E-18 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS06540 1769240f550a2bc0c9bc329c0128b6ca 279 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 45 277 3.4E-32 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS18205 c4fcb4ba45b4fa544e366eae9c3e2831 448 Gene3D G3DSA:3.90.350.10 115 361 1.3E-5 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS18205 c4fcb4ba45b4fa544e366eae9c3e2831 448 Pfam PF13701 Transposase DDE domain group 1 12 446 1.0E-28 T 29-03-2018 IPR025668 Transposase DDE domain THSYN_RS01825 c4fcb4ba45b4fa544e366eae9c3e2831 448 Gene3D G3DSA:3.90.350.10 115 361 1.3E-5 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS01825 c4fcb4ba45b4fa544e366eae9c3e2831 448 Pfam PF13701 Transposase DDE domain group 1 12 446 1.0E-28 T 29-03-2018 IPR025668 Transposase DDE domain THSYN_RS04940 c4fcb4ba45b4fa544e366eae9c3e2831 448 Gene3D G3DSA:3.90.350.10 115 361 1.3E-5 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS04940 c4fcb4ba45b4fa544e366eae9c3e2831 448 Pfam PF13701 Transposase DDE domain group 1 12 446 1.0E-28 T 29-03-2018 IPR025668 Transposase DDE domain THSYN_RS15675 c4fcb4ba45b4fa544e366eae9c3e2831 448 Gene3D G3DSA:3.90.350.10 115 361 1.3E-5 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS15675 c4fcb4ba45b4fa544e366eae9c3e2831 448 Pfam PF13701 Transposase DDE domain group 1 12 446 1.0E-28 T 29-03-2018 IPR025668 Transposase DDE domain THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 Gene3D G3DSA:3.30.70.1430 563 662 4.0E-22 T 29-03-2018 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 SUPERFAMILY SSF82693 666 715 3.66E-27 T 29-03-2018 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 SUPERFAMILY SSF82693 805 854 3.66E-27 T 29-03-2018 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 Gene3D G3DSA:3.30.2090.10 180 275 4.2E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 Gene3D G3DSA:3.30.70.1440 666 762 1.9E-17 T 29-03-2018 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 SUPERFAMILY SSF82693 561 665 1.02E-29 T 29-03-2018 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 SUPERFAMILY SSF82693 38 131 6.1E-27 T 29-03-2018 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 SUPERFAMILY SSF82866 297 497 4.45E-50 T 29-03-2018 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 SUPERFAMILY SSF82693 135 182 6.28E-17 T 29-03-2018 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 SUPERFAMILY SSF82693 274 330 6.28E-17 T 29-03-2018 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 Gene3D G3DSA:1.20.1640.10 820 1027 2.5E-35 T 29-03-2018 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 Pfam PF00873 AcrB/AcrD/AcrF family 1 1024 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 SUPERFAMILY SSF82714 716 804 4.84E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 Gene3D G3DSA:3.30.70.1430 38 140 2.2E-26 T 29-03-2018 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 SUPERFAMILY SSF82866 828 1024 2.22E-42 T 29-03-2018 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 SUPERFAMILY SSF82714 182 272 6.02E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1032 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 Gene3D G3DSA:1.20.1640.10 286 504 2.4E-44 T 29-03-2018 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.1E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 PRINTS PR00702 Acriflavin resistance protein family signature 615 629 1.1E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.1E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 1.1E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.1E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.1E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 1.1E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.1E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS32585 14b4b5ad3a372cc7ce69137862e3c495 1059 PRINTS PR00702 Acriflavin resistance protein family signature 548 565 1.1E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS05585 633467dfe2670c9925c559efbb40cfc6 140 Gene3D G3DSA:1.20.120.330 1 138 6.1E-19 T 29-03-2018 THSYN_RS05585 633467dfe2670c9925c559efbb40cfc6 140 SUPERFAMILY SSF81593 32 134 5.1E-18 T 29-03-2018 THSYN_RS05585 633467dfe2670c9925c559efbb40cfc6 140 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 3 134 8.5E-18 T 29-03-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 THSYN_RS05860 e8cf20c06369991bebe4ba6deba9c27d 363 Gene3D G3DSA:3.30.300.130 2 89 1.6E-12 T 29-03-2018 IPR034904 Fe-S cluster assembly domain THSYN_RS05860 e8cf20c06369991bebe4ba6deba9c27d 363 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 97 339 7.6E-104 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 THSYN_RS05860 e8cf20c06369991bebe4ba6deba9c27d 363 Hamap MF_02040 Iron-sulfur cluster carrier protein. 93 341 38.355 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein THSYN_RS05860 e8cf20c06369991bebe4ba6deba9c27d 363 Gene3D G3DSA:3.40.50.300 90 319 3.2E-67 T 29-03-2018 THSYN_RS05860 e8cf20c06369991bebe4ba6deba9c27d 363 Pfam PF01883 Iron-sulfur cluster assembly protein 7 78 6.2E-15 T 29-03-2018 IPR002744 MIP18 family-like THSYN_RS05860 e8cf20c06369991bebe4ba6deba9c27d 363 SUPERFAMILY SSF52540 100 345 1.23E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05860 e8cf20c06369991bebe4ba6deba9c27d 363 SUPERFAMILY SSF117916 4 86 4.25E-15 T 29-03-2018 IPR034904 Fe-S cluster assembly domain THSYN_RS05860 e8cf20c06369991bebe4ba6deba9c27d 363 ProSitePatterns PS01215 Mrp family signature. 204 220 - T 29-03-2018 IPR000808 Mrp, conserved site GO:0005524 THSYN_RS24730 2057809994ef23cc7a62076a89a56ad1 117 SUPERFAMILY SSF55729 20 97 2.61E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS24730 2057809994ef23cc7a62076a89a56ad1 117 Gene3D G3DSA:3.40.630.30 4 102 7.9E-14 T 29-03-2018 THSYN_RS24730 2057809994ef23cc7a62076a89a56ad1 117 Pfam PF13508 Acetyltransferase (GNAT) domain 29 90 1.2E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 Gene3D G3DSA:2.40.10.10 164 263 4.8E-39 T 29-03-2018 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 Pfam PF13180 PDZ domain 267 353 5.8E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 Gene3D G3DSA:2.30.42.10 264 363 4.9E-23 T 29-03-2018 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 Gene3D G3DSA:2.30.42.10 383 449 6.3E-12 T 29-03-2018 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 40 449 1.1E-136 T 29-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 Gene3D G3DSA:2.40.10.10 37 163 3.6E-34 T 29-03-2018 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 SUPERFAMILY SSF50494 38 257 2.96E-67 T 29-03-2018 IPR009003 Peptidase S1, PA clan THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 PRINTS PR00834 HtrA/DegQ protease family signature 306 318 1.2E-54 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 PRINTS PR00834 HtrA/DegQ protease family signature 163 187 1.2E-54 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 PRINTS PR00834 HtrA/DegQ protease family signature 102 114 1.2E-54 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 PRINTS PR00834 HtrA/DegQ protease family signature 220 237 1.2E-54 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 PRINTS PR00834 HtrA/DegQ protease family signature 123 143 1.2E-54 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 PRINTS PR00834 HtrA/DegQ protease family signature 198 215 1.2E-54 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 SUPERFAMILY SSF50156 386 447 1.45E-12 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 Pfam PF13365 Trypsin-like peptidase domain 92 227 9.2E-34 T 29-03-2018 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 SUPERFAMILY SSF50156 224 348 7.23E-23 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 SMART SM00228 266 348 2.5E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08660 0a2ce91bacc9fe3f838e76af48b4cdd1 452 SMART SM00228 372 444 2.7E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS09690 b9b788f5f846374b18f25f1a0d26e5e7 580 Pfam PF03050 Transposase IS66 family 226 521 1.9E-43 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS18290 b9b788f5f846374b18f25f1a0d26e5e7 580 Pfam PF03050 Transposase IS66 family 226 521 1.9E-43 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS19715 9c3e2e81aa656a3b256d23601a25b4ce 197 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 94 197 1.8E-39 T 29-03-2018 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 THSYN_RS19715 9c3e2e81aa656a3b256d23601a25b4ce 197 Pfam PF00691 OmpA family 96 190 1.2E-16 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS19715 9c3e2e81aa656a3b256d23601a25b4ce 197 Gene3D G3DSA:3.30.1330.60 38 197 2.8E-30 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS19715 9c3e2e81aa656a3b256d23601a25b4ce 197 PRINTS PR01021 OMPA domain signature 127 142 8.9E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS19715 9c3e2e81aa656a3b256d23601a25b4ce 197 PRINTS PR01021 OMPA domain signature 142 158 8.9E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS19715 9c3e2e81aa656a3b256d23601a25b4ce 197 PRINTS PR01021 OMPA domain signature 97 119 8.9E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS19715 9c3e2e81aa656a3b256d23601a25b4ce 197 SUPERFAMILY SSF103088 90 197 2.35E-31 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.25.40.10 309 386 3.5E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 707 740 74.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 469 502 0.01 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 301 334 45.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 131 164 0.0073 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 28 61 71.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 62 95 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 503 536 43.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 367 400 10.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 605 638 41.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 267 300 27.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 774 807 460.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 401 434 81.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 199 232 0.42 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 639 672 35.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SMART SM00028 876 909 44.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SUPERFAMILY SSF48452 34 163 1.0E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.25.40.10 581 631 4.6E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.25.40.10 113 193 7.6E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.20.120.420 435 483 1.9E-4 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.25.40.10 817 923 4.7E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.25.40.10 387 434 4.8E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.25.40.10 701 786 2.7E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Pfam PF13181 Tetratricopeptide repeat 369 399 0.0055 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.25.40.10 484 517 5.3E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SUPERFAMILY SSF48452 579 912 8.34E-30 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.25.40.10 787 816 1.3E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Pfam PF09976 Tetratricopeptide repeat-like domain 41 167 6.9E-11 T 29-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 TIGRFAM TIGR02917 PEP_TPR_lipo: putative PEP-CTERM system TPR-repeat lipoprotein 13 903 1.5E-226 T 29-03-2018 IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SUPERFAMILY SSF48452 131 367 9.48E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.25.40.10 23 112 2.7E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 SUPERFAMILY SSF48452 369 590 2.16E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.25.40.10 632 700 2.2E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Pfam PF13432 Tetratricopeptide repeat 508 568 4.8E-6 T 29-03-2018 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.25.40.10 518 580 3.8E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.25.40.10 243 308 3.8E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Gene3D G3DSA:1.25.40.10 194 242 1.0E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Pfam PF14559 Tetratricopeptide repeat 651 706 4.6E-7 T 29-03-2018 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Pfam PF14559 Tetratricopeptide repeat 211 259 2.4E-6 T 29-03-2018 THSYN_RS01945 4b57a0569c29f1d394c6da22e3b5aa17 924 Pfam PF14559 Tetratricopeptide repeat 855 917 1.4E-7 T 29-03-2018 THSYN_RS08860 d03480d9b3aab33a54f30da79f41a7b2 304 SUPERFAMILY SSF46626 99 186 1.95E-22 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS08860 d03480d9b3aab33a54f30da79f41a7b2 304 SUPERFAMILY SSF46626 29 63 1.95E-22 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS08860 d03480d9b3aab33a54f30da79f41a7b2 304 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 110 182 3.8E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS08860 d03480d9b3aab33a54f30da79f41a7b2 304 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 9 56 3.4E-21 T 29-03-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal THSYN_RS08860 d03480d9b3aab33a54f30da79f41a7b2 304 Gene3D G3DSA:1.10.760.10 68 192 5.8E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS08860 d03480d9b3aab33a54f30da79f41a7b2 304 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 11 303 2.5E-60 T 29-03-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III THSYN_RS08860 d03480d9b3aab33a54f30da79f41a7b2 304 Pfam PF00034 Cytochrome c 195 300 1.4E-5 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS08860 d03480d9b3aab33a54f30da79f41a7b2 304 PIRSF PIRSF000006 1 304 1.4E-63 T 29-03-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III THSYN_RS08860 d03480d9b3aab33a54f30da79f41a7b2 304 SUPERFAMILY SSF46626 194 302 2.81E-10 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS08860 d03480d9b3aab33a54f30da79f41a7b2 304 Gene3D G3DSA:1.10.760.10 193 304 8.5E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS30075 28360871a1fce6bc9170539b0ed70f96 110 Pfam PF03683 Uncharacterised protein family (UPF0175) 41 107 2.4E-13 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS30075 28360871a1fce6bc9170539b0ed70f96 110 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 7 39 1.8E-5 T 29-03-2018 THSYN_RS30075 28360871a1fce6bc9170539b0ed70f96 110 Gene3D G3DSA:3.40.1620.10 1 103 8.9E-7 T 29-03-2018 THSYN_RS26420 496116d71e4ca2e15ef6ce40787f8c85 422 Gene3D G3DSA:3.30.70.20 5 43 0.0063 T 29-03-2018 THSYN_RS26420 496116d71e4ca2e15ef6ce40787f8c85 422 SUPERFAMILY SSF54862 31 121 2.05E-15 T 29-03-2018 THSYN_RS26420 496116d71e4ca2e15ef6ce40787f8c85 422 Gene3D G3DSA:3.30.70.20 93 288 7.8E-4 T 29-03-2018 THSYN_RS26420 496116d71e4ca2e15ef6ce40787f8c85 422 Pfam PF02754 Cysteine-rich domain 198 244 0.046 T 29-03-2018 IPR004017 Cysteine-rich domain THSYN_RS26420 496116d71e4ca2e15ef6ce40787f8c85 422 Pfam PF02754 Cysteine-rich domain 309 393 9.2E-11 T 29-03-2018 IPR004017 Cysteine-rich domain THSYN_RS26420 496116d71e4ca2e15ef6ce40787f8c85 422 Pfam PF13183 4Fe-4S dicluster domain 34 99 3.2E-11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS26420 496116d71e4ca2e15ef6ce40787f8c85 422 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 36 47 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS26420 496116d71e4ca2e15ef6ce40787f8c85 422 PIRSF PIRSF000139 18 260 7.4E-44 T 29-03-2018 THSYN_RS26420 496116d71e4ca2e15ef6ce40787f8c85 422 PIRSF PIRSF000139 284 421 1.1E-26 T 29-03-2018 THSYN_RS26420 496116d71e4ca2e15ef6ce40787f8c85 422 Gene3D G3DSA:3.30.70.20 44 92 1.2E-8 T 29-03-2018 THSYN_RS26420 496116d71e4ca2e15ef6ce40787f8c85 422 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS13820 9391f9d31dfad989bda3c19f0410f612 730 Pfam PF01103 Surface antigen 490 650 1.2E-8 T 29-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 THSYN_RS13820 9391f9d31dfad989bda3c19f0410f612 730 Gene3D G3DSA:2.40.160.50 364 728 3.2E-23 T 29-03-2018 THSYN_RS13820 9391f9d31dfad989bda3c19f0410f612 730 Pfam PF01734 Patatin-like phospholipase 29 220 1.5E-25 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 THSYN_RS13820 9391f9d31dfad989bda3c19f0410f612 730 Gene3D G3DSA:3.40.1090.10 19 284 5.2E-45 T 29-03-2018 THSYN_RS13820 9391f9d31dfad989bda3c19f0410f612 730 SUPERFAMILY SSF52151 126 317 3.14E-54 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS13820 9391f9d31dfad989bda3c19f0410f612 730 SUPERFAMILY SSF52151 24 96 3.14E-54 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS24915 40815f9b811b7e18138c9ccb864c7f0b 209 Pfam PF01725 Ham1 family 10 197 5.3E-56 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 THSYN_RS24915 40815f9b811b7e18138c9ccb864c7f0b 209 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 9 199 4.2E-56 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 THSYN_RS24915 40815f9b811b7e18138c9ccb864c7f0b 209 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 8 202 48.613 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 THSYN_RS24915 40815f9b811b7e18138c9ccb864c7f0b 209 Gene3D G3DSA:3.90.950.10 1 204 8.2E-75 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THSYN_RS24915 40815f9b811b7e18138c9ccb864c7f0b 209 SUPERFAMILY SSF52972 8 200 6.54E-70 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THSYN_RS05015 e0837c65cfe70f4d0a4a7cf7ac33fd99 341 Gene3D G3DSA:1.10.40.50 277 338 4.2E-18 T 29-03-2018 THSYN_RS05015 e0837c65cfe70f4d0a4a7cf7ac33fd99 341 Gene3D G3DSA:2.40.50.140 44 103 7.8E-14 T 29-03-2018 THSYN_RS05015 e0837c65cfe70f4d0a4a7cf7ac33fd99 341 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 47 340 30.414 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 THSYN_RS05015 e0837c65cfe70f4d0a4a7cf7ac33fd99 341 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 81 333 8.6E-60 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 THSYN_RS05015 e0837c65cfe70f4d0a4a7cf7ac33fd99 341 SUPERFAMILY SSF52540 118 332 2.09E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05015 e0837c65cfe70f4d0a4a7cf7ac33fd99 341 Gene3D G3DSA:3.40.50.300 121 275 1.5E-17 T 29-03-2018 THSYN_RS05015 e0837c65cfe70f4d0a4a7cf7ac33fd99 341 Pfam PF03193 RsgA GTPase 102 275 2.3E-39 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 THSYN_RS00160 00c6a3dda0a66628ae58246b926e9094 402 Gene3D G3DSA:3.30.70.1120 100 167 0.0066 T 29-03-2018 THSYN_RS00160 00c6a3dda0a66628ae58246b926e9094 402 Pfam PF00482 Type II secretion system (T2SS), protein F 69 191 2.0E-29 T 29-03-2018 IPR018076 Type II secretion system F domain THSYN_RS00160 00c6a3dda0a66628ae58246b926e9094 402 Pfam PF00482 Type II secretion system (T2SS), protein F 272 392 2.7E-23 T 29-03-2018 IPR018076 Type II secretion system F domain THSYN_RS00160 00c6a3dda0a66628ae58246b926e9094 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 382 401 1.3E-21 T 29-03-2018 IPR003004 GspF/PilC family THSYN_RS00160 00c6a3dda0a66628ae58246b926e9094 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 366 380 1.3E-21 T 29-03-2018 IPR003004 GspF/PilC family THSYN_RS00160 00c6a3dda0a66628ae58246b926e9094 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 64 76 1.3E-21 T 29-03-2018 IPR003004 GspF/PilC family THSYN_RS00160 00c6a3dda0a66628ae58246b926e9094 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 163 191 1.3E-21 T 29-03-2018 IPR003004 GspF/PilC family THSYN_RS23900 0dec6b253d0b1714a03fbddf9c519999 275 Gene3D G3DSA:2.40.50.140 1 114 4.9E-44 T 29-03-2018 THSYN_RS23900 0dec6b253d0b1714a03fbddf9c519999 275 PIRSF PIRSF002158 12 275 8.0E-101 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23900 0dec6b253d0b1714a03fbddf9c519999 275 SMART SM01382 124 252 2.4E-89 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 THSYN_RS23900 0dec6b253d0b1714a03fbddf9c519999 275 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.264 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 THSYN_RS23900 0dec6b253d0b1714a03fbddf9c519999 275 SUPERFAMILY SSF50249 3 124 9.94E-47 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS23900 0dec6b253d0b1714a03fbddf9c519999 275 Gene3D G3DSA:4.10.950.10 197 273 1.5E-35 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 THSYN_RS23900 0dec6b253d0b1714a03fbddf9c519999 275 SMART SM01383 42 118 6.5E-44 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23900 0dec6b253d0b1714a03fbddf9c519999 275 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 272 3.0E-126 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 THSYN_RS23900 0dec6b253d0b1714a03fbddf9c519999 275 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 250 6.0E-56 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 THSYN_RS23900 0dec6b253d0b1714a03fbddf9c519999 275 SUPERFAMILY SSF50104 126 272 1.44E-60 T 29-03-2018 IPR008991 Translation protein SH3-like domain THSYN_RS23900 0dec6b253d0b1714a03fbddf9c519999 275 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23900 0dec6b253d0b1714a03fbddf9c519999 275 Gene3D G3DSA:2.30.30.30 119 195 2.0E-31 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 THSYN_RS23900 0dec6b253d0b1714a03fbddf9c519999 275 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 116 1.1E-31 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS02160 ab4e5b5974436f6a9632ad51b3a97c16 497 SMART SM00387 373 478 2.0E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02160 ab4e5b5974436f6a9632ad51b3a97c16 497 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 421 1.8E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS02160 ab4e5b5974436f6a9632ad51b3a97c16 497 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 456 1.8E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS02160 ab4e5b5974436f6a9632ad51b3a97c16 497 Gene3D G3DSA:3.30.565.10 223 476 7.5E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02160 ab4e5b5974436f6a9632ad51b3a97c16 497 SUPERFAMILY SSF55874 338 475 1.44E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02160 ab4e5b5974436f6a9632ad51b3a97c16 497 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 378 475 1.7E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS27780 e364b747a4c0f33149c3aa416a0ccb04 294 Pfam PF00950 ABC 3 transport family 11 265 6.2E-71 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 THSYN_RS27780 e364b747a4c0f33149c3aa416a0ccb04 294 SUPERFAMILY SSF81345 8 262 7.45E-36 T 29-03-2018 IPR029022 ABC transporter, BtuC-like THSYN_RS27780 e364b747a4c0f33149c3aa416a0ccb04 294 Gene3D G3DSA:1.10.3470.10 6 277 1.2E-24 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like THSYN_RS26930 fc7a3b40237a72781cc5e1a8dc6dbf93 406 Pfam PF13776 Domain of unknown function (DUF4172) 3 84 1.2E-21 T 29-03-2018 IPR025230 Domain of unknown function DUF4172 THSYN_RS26930 fc7a3b40237a72781cc5e1a8dc6dbf93 406 Gene3D G3DSA:1.10.3290.10 25 289 1.6E-47 T 29-03-2018 IPR003812 Fido domain THSYN_RS26930 fc7a3b40237a72781cc5e1a8dc6dbf93 406 Gene3D G3DSA:1.10.10.10 297 370 9.4E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26930 fc7a3b40237a72781cc5e1a8dc6dbf93 406 SUPERFAMILY SSF140931 98 283 2.49E-34 T 29-03-2018 IPR003812 Fido domain THSYN_RS26930 fc7a3b40237a72781cc5e1a8dc6dbf93 406 Pfam PF02661 Fic/DOC family 112 223 6.8E-19 T 29-03-2018 IPR003812 Fido domain THSYN_RS02060 0c6b669f5629de463b71e5a3d7d8ff12 500 PIRSF PIRSF000774 1 500 1.2E-149 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THSYN_RS02060 0c6b669f5629de463b71e5a3d7d8ff12 500 Gene3D G3DSA:1.10.10.10 345 436 7.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS02060 0c6b669f5629de463b71e5a3d7d8ff12 500 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 478 485 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THSYN_RS02060 0c6b669f5629de463b71e5a3d7d8ff12 500 PRINTS PR00045 Sigma-54 factor signature 473 491 1.7E-31 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THSYN_RS02060 0c6b669f5629de463b71e5a3d7d8ff12 500 PRINTS PR00045 Sigma-54 factor signature 399 411 1.7E-31 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THSYN_RS02060 0c6b669f5629de463b71e5a3d7d8ff12 500 PRINTS PR00045 Sigma-54 factor signature 202 219 1.7E-31 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THSYN_RS02060 0c6b669f5629de463b71e5a3d7d8ff12 500 PRINTS PR00045 Sigma-54 factor signature 415 426 1.7E-31 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THSYN_RS02060 0c6b669f5629de463b71e5a3d7d8ff12 500 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 49 1.8E-14 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THSYN_RS02060 0c6b669f5629de463b71e5a3d7d8ff12 500 Pfam PF04963 Sigma-54 factor, core binding domain 129 326 1.6E-56 T 29-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 THSYN_RS02060 0c6b669f5629de463b71e5a3d7d8ff12 500 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 497 9.2E-142 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THSYN_RS02060 0c6b669f5629de463b71e5a3d7d8ff12 500 Pfam PF04552 Sigma-54, DNA binding domain 342 498 2.7E-67 T 29-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding THSYN_RS01280 1049d8217bf690aa7f316cd8cdec5d1b 94 SMART SM00530 34 88 3.7E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS01280 1049d8217bf690aa7f316cd8cdec5d1b 94 SUPERFAMILY SSF47413 35 78 7.68E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS01280 1049d8217bf690aa7f316cd8cdec5d1b 94 Pfam PF15731 Antitoxin component of bacterial toxin-antitoxin system, MqsA 7 91 1.8E-11 T 29-03-2018 IPR032758 Antitoxin MqsA/HigA-2 THSYN_RS01280 1049d8217bf690aa7f316cd8cdec5d1b 94 Gene3D G3DSA:1.10.260.40 3 92 2.2E-15 T 29-03-2018 THSYN_RS26590 9f64405fe5bea2f470ae6028624563a3 275 PIRSF PIRSF004808 16 257 3.4E-62 T 29-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 THSYN_RS26590 9f64405fe5bea2f470ae6028624563a3 275 Pfam PF00588 SpoU rRNA Methylase family 20 169 1.1E-27 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 THSYN_RS26590 9f64405fe5bea2f470ae6028624563a3 275 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 18 251 2.5E-63 T 29-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 THSYN_RS26590 9f64405fe5bea2f470ae6028624563a3 275 SUPERFAMILY SSF75217 18 178 4.97E-33 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases THSYN_RS26590 9f64405fe5bea2f470ae6028624563a3 275 Gene3D G3DSA:3.40.1280.10 16 179 4.3E-39 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THSYN_RS22145 d45412a1793158672c9f1941b1233b3c 239 Pfam PF13548 Domain of unknown function (DUF4126) 8 178 1.1E-54 T 29-03-2018 IPR025196 Domain of unknown function DUF4126 THSYN_RS02335 b034fac2ce09a7365b8da2df8d8be3e4 140 Pfam PF00816 H-NS histone family 60 111 2.0E-11 T 29-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 THSYN_RS02335 b034fac2ce09a7365b8da2df8d8be3e4 140 SMART SM00528 75 118 4.8E-8 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 THSYN_RS02335 b034fac2ce09a7365b8da2df8d8be3e4 140 Gene3D G3DSA:4.10.430.10 81 117 1.6E-12 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 THSYN_RS02335 b034fac2ce09a7365b8da2df8d8be3e4 140 SUPERFAMILY SSF81273 81 115 3.88E-8 T 29-03-2018 THSYN_RS00915 53ede8c5eb92161835de1d88fce33317 462 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 17 460 3.1E-171 T 29-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 THSYN_RS00915 53ede8c5eb92161835de1d88fce33317 462 SUPERFAMILY SSF53633 15 312 2.51E-64 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase THSYN_RS00915 53ede8c5eb92161835de1d88fce33317 462 Pfam PF00583 Acetyltransferase (GNAT) family 343 421 9.0E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS00915 53ede8c5eb92161835de1d88fce33317 462 Gene3D G3DSA:3.40.630.30 315 461 4.0E-24 T 29-03-2018 THSYN_RS00915 53ede8c5eb92161835de1d88fce33317 462 SUPERFAMILY SSF55729 316 437 1.89E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS00915 53ede8c5eb92161835de1d88fce33317 462 Gene3D G3DSA:3.40.1160.10 15 313 6.1E-62 T 29-03-2018 THSYN_RS00915 53ede8c5eb92161835de1d88fce33317 462 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 460 195.374 T 29-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 THSYN_RS00915 53ede8c5eb92161835de1d88fce33317 462 Pfam PF00696 Amino acid kinase family 35 230 7.8E-24 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase THSYN_RS00915 53ede8c5eb92161835de1d88fce33317 462 PIRSF PIRSF000423 8 460 7.8E-180 T 29-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 THSYN_RS25945 bbaced8c7703fc7f723cbb9584def329 139 Pfam PF02915 Rubrerythrin 12 133 5.5E-26 T 29-03-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 THSYN_RS25945 bbaced8c7703fc7f723cbb9584def329 139 Gene3D G3DSA:1.20.1260.10 2 68 2.0E-18 T 29-03-2018 IPR012347 Ferritin-related THSYN_RS25945 bbaced8c7703fc7f723cbb9584def329 139 Gene3D G3DSA:1.20.1260.10 69 139 1.1E-12 T 29-03-2018 IPR012347 Ferritin-related THSYN_RS25945 bbaced8c7703fc7f723cbb9584def329 139 SUPERFAMILY SSF47240 3 138 2.47E-41 T 29-03-2018 IPR009078 Ferritin-like superfamily THSYN_RS05470 7fb47c3dc4a9fbacfc978094469255ee 436 Pfam PF12002 MgsA AAA+ ATPase C terminal 258 424 2.1E-69 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal THSYN_RS05470 7fb47c3dc4a9fbacfc978094469255ee 436 Gene3D G3DSA:1.10.8.60 149 233 1.3E-20 T 29-03-2018 THSYN_RS05470 7fb47c3dc4a9fbacfc978094469255ee 436 Pfam PF16193 AAA C-terminal domain 184 257 1.4E-18 T 29-03-2018 IPR032423 AAA C-terminal domain THSYN_RS05470 7fb47c3dc4a9fbacfc978094469255ee 436 SMART SM00382 43 160 1.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS05470 7fb47c3dc4a9fbacfc978094469255ee 436 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 47 156 4.6E-17 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS05470 7fb47c3dc4a9fbacfc978094469255ee 436 SUPERFAMILY SSF48019 242 424 1.53E-75 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 THSYN_RS05470 7fb47c3dc4a9fbacfc978094469255ee 436 Gene3D G3DSA:1.10.3710.10 338 436 5.0E-36 T 29-03-2018 THSYN_RS05470 7fb47c3dc4a9fbacfc978094469255ee 436 Gene3D G3DSA:3.40.50.300 2 148 1.9E-27 T 29-03-2018 THSYN_RS05470 7fb47c3dc4a9fbacfc978094469255ee 436 SUPERFAMILY SSF52540 7 229 4.09E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05470 7fb47c3dc4a9fbacfc978094469255ee 436 Gene3D G3DSA:1.20.272.10 242 336 7.7E-38 T 29-03-2018 THSYN_RS02755 8f7707dbfcf9f27ff5750dd7a534f5d4 89 Pfam PF11154 Protein of unknown function (DUF2934) 16 51 1.2E-13 T 29-03-2018 IPR021327 Protein of unknown function DUF2934 THSYN_RS28810 3c459e2add8af8201c1b2af36e253079 337 Pfam PF02661 Fic/DOC family 103 198 2.0E-20 T 29-03-2018 IPR003812 Fido domain THSYN_RS28810 3c459e2add8af8201c1b2af36e253079 337 Gene3D G3DSA:1.10.3290.10 13 251 3.3E-51 T 29-03-2018 IPR003812 Fido domain THSYN_RS28810 3c459e2add8af8201c1b2af36e253079 337 SUPERFAMILY SSF140931 81 249 1.83E-40 T 29-03-2018 IPR003812 Fido domain THSYN_RS02585 97ba33250c017fcc7ea54c527dd474a7 302 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 11 300 1.5E-108 T 29-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 THSYN_RS02585 97ba33250c017fcc7ea54c527dd474a7 302 Pfam PF00589 Phage integrase family 117 284 4.1E-43 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS02585 97ba33250c017fcc7ea54c527dd474a7 302 Gene3D G3DSA:1.10.150.130 7 115 1.9E-23 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS02585 97ba33250c017fcc7ea54c527dd474a7 302 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 94 3.1E-17 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS02585 97ba33250c017fcc7ea54c527dd474a7 302 SUPERFAMILY SSF56349 13 292 2.56E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS02585 97ba33250c017fcc7ea54c527dd474a7 302 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 7 298 57.009 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD THSYN_RS02585 97ba33250c017fcc7ea54c527dd474a7 302 Gene3D G3DSA:1.10.443.10 116 292 1.2E-42 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS17405 7520c7d5cfcd19d8156e82deb348f8f2 548 Gene3D G3DSA:1.10.1130.10 231 514 2.4E-18 T 29-03-2018 THSYN_RS17405 7520c7d5cfcd19d8156e82deb348f8f2 548 Gene3D G3DSA:1.10.1130.10 64 230 1.2E-15 T 29-03-2018 THSYN_RS17405 7520c7d5cfcd19d8156e82deb348f8f2 548 SUPERFAMILY SSF48695 55 496 1.14E-90 T 29-03-2018 IPR011031 Multihaem cytochrome THSYN_RS17405 7520c7d5cfcd19d8156e82deb348f8f2 548 PIRSF PIRSF039014 10 544 1.2E-155 T 29-03-2018 IPR024673 Octaheme c-type cytochrome THSYN_RS17405 7520c7d5cfcd19d8156e82deb348f8f2 548 TIGRFAM TIGR04315 octaheme_Shew: octaheme c-type cytochrome, tetrathionate reductase family 47 503 4.9E-182 T 29-03-2018 IPR024673 Octaheme c-type cytochrome THSYN_RS17405 7520c7d5cfcd19d8156e82deb348f8f2 548 Pfam PF13435 Cytochrome c554 and c-prime 233 304 0.011 T 29-03-2018 IPR023155 Cytochrome c-552/4 THSYN_RS17405 7520c7d5cfcd19d8156e82deb348f8f2 548 Pfam PF11783 Cytochrome c bacterial 317 492 5.4E-61 T 29-03-2018 IPR024673 Octaheme c-type cytochrome THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SMART SM00138 207 467 8.0E-67 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SUPERFAMILY SSF55785 938 1065 1.57E-30 T 29-03-2018 IPR000014 PAS domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SMART SM00091 1097 1163 6.4E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SMART SM00091 707 772 1.8 T 29-03-2018 IPR000014 PAS domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SMART SM00091 827 893 0.0063 T 29-03-2018 IPR000014 PAS domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SMART SM00091 952 1018 2.2E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SMART SM00387 1349 1460 2.0E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Pfam PF00989 PAS fold 953 1064 7.0E-12 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Pfam PF00989 PAS fold 1098 1212 5.0E-10 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Pfam PF13596 PAS domain 710 812 1.9E-12 T 29-03-2018 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Gene3D G3DSA:1.20.120.160 1627 1732 9.7E-11 T 29-03-2018 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SUPERFAMILY SSF47757 201 275 1.83E-10 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Gene3D G3DSA:3.40.50.150 272 469 2.1E-38 T 29-03-2018 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 PRINTS PR00996 Glutamate methyltransferase family signature 305 325 8.1E-21 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 PRINTS PR00996 Glutamate methyltransferase family signature 341 357 8.1E-21 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 PRINTS PR00996 Glutamate methyltransferase family signature 426 449 8.1E-21 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 PRINTS PR00996 Glutamate methyltransferase family signature 407 421 8.1E-21 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Gene3D G3DSA:1.20.5.400 634 701 1.9E-6 T 29-03-2018 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Gene3D G3DSA:3.30.450.20 1087 1226 1.2E-27 T 29-03-2018 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SUPERFAMILY SSF47226 1580 1593 3.4E-13 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SUPERFAMILY SSF47226 1629 1718 3.4E-13 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Pfam PF00072 Response regulator receiver domain 1486 1597 6.1E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Gene3D G3DSA:1.10.287.130 1227 1298 2.6E-15 T 29-03-2018 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Pfam PF01339 CheB methylesterase 10 184 3.3E-47 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1237 1302 3.5E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SUPERFAMILY SSF52738 6 189 2.62E-47 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1349 1457 2.0E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SUPERFAMILY SSF47384 1222 1303 1.33E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SUPERFAMILY SSF52172 1483 1608 4.84E-33 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Pfam PF01739 CheR methyltransferase, SAM binding domain 275 461 7.5E-46 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Pfam PF08448 PAS fold 834 942 1.5E-16 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SMART SM00448 1484 1597 1.7E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SMART SM00086 1025 1067 0.0013 T 29-03-2018 IPR001610 PAC motif THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SMART SM00086 1175 1216 100.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SMART SM00086 899 940 62.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SMART SM00086 776 815 310.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SUPERFAMILY SSF53335 274 466 2.72E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SUPERFAMILY SSF55874 1291 1458 4.71E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Gene3D G3DSA:1.10.155.10 200 271 5.0E-11 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Gene3D G3DSA:3.30.450.20 941 1086 1.6E-36 T 29-03-2018 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Gene3D G3DSA:3.30.450.20 821 940 7.1E-22 T 29-03-2018 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SUPERFAMILY SSF55785 695 813 5.23E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 1094 1222 8.7E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 824 947 1.1E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 949 1073 3.3E-25 T 29-03-2018 IPR000014 PAS domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Gene3D G3DSA:3.40.50.2300 1469 1618 9.7E-35 T 29-03-2018 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SMART SM00388 1236 1302 1.6E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Gene3D G3DSA:3.40.50.180 1 194 4.9E-56 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SUPERFAMILY SSF55785 1090 1214 1.45E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 SUPERFAMILY SSF55785 812 938 1.08E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Gene3D G3DSA:3.30.565.10 1306 1466 3.5E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Gene3D G3DSA:3.30.450.20 702 820 1.5E-17 T 29-03-2018 THSYN_RS14520 cd73abe26df07502545d9908da08285a 1742 Pfam PF03705 CheR methyltransferase, all-alpha domain 210 260 2.0E-8 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 SUPERFAMILY SSF56014 141 340 1.28E-55 T 29-03-2018 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 474 490 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 SUPERFAMILY SSF55124 342 418 3.76E-21 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 15 555 5.0E-258 T 29-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 SUPERFAMILY SSF55124 10 140 2.94E-28 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 348 412 6.1E-14 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 72 130 1.5E-13 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 3 567 57.198 T 29-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 Gene3D G3DSA:3.30.413.10 423 564 1.3E-27 T 29-03-2018 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 SUPERFAMILY SSF56014 425 564 1.44E-35 T 29-03-2018 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 Gene3D G3DSA:3.30.413.10 134 342 5.8E-49 T 29-03-2018 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 166 324 3.3E-46 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 428 554 2.9E-6 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 PRINTS PR00397 Sirohaem Fe-binding site signature 426 444 3.0E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS27875 3fef5bab7a004da29b2dd6917e3cc936 567 PRINTS PR00397 Sirohaem Fe-binding site signature 474 492 3.0E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS12465 34fd9c3e0235cfb57d01873164cbefa5 231 Gene3D G3DSA:3.40.50.2300 2 140 5.3E-37 T 29-03-2018 THSYN_RS12465 34fd9c3e0235cfb57d01873164cbefa5 231 SMART SM00448 3 114 6.9E-43 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS12465 34fd9c3e0235cfb57d01873164cbefa5 231 Gene3D G3DSA:1.10.10.10 141 231 1.6E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS12465 34fd9c3e0235cfb57d01873164cbefa5 231 SMART SM00862 152 228 7.6E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS12465 34fd9c3e0235cfb57d01873164cbefa5 231 Pfam PF00072 Response regulator receiver domain 5 115 4.6E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS12465 34fd9c3e0235cfb57d01873164cbefa5 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 2.5E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS12465 34fd9c3e0235cfb57d01873164cbefa5 231 SUPERFAMILY SSF46894 132 229 9.64E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS12465 34fd9c3e0235cfb57d01873164cbefa5 231 SUPERFAMILY SSF52172 1 126 1.39E-40 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS13865 9192c590b1431043e2a3da526e2fbbd3 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 2.6E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS13865 9192c590b1431043e2a3da526e2fbbd3 238 SUPERFAMILY SSF52172 2 125 4.55E-38 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS13865 9192c590b1431043e2a3da526e2fbbd3 238 Gene3D G3DSA:3.40.50.2300 1 125 3.5E-32 T 29-03-2018 THSYN_RS13865 9192c590b1431043e2a3da526e2fbbd3 238 Pfam PF00072 Response regulator receiver domain 8 116 1.5E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS13865 9192c590b1431043e2a3da526e2fbbd3 238 SMART SM00862 151 229 6.3E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS13865 9192c590b1431043e2a3da526e2fbbd3 238 SUPERFAMILY SSF46894 130 230 1.53E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS13865 9192c590b1431043e2a3da526e2fbbd3 238 SMART SM00448 5 116 6.0E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS13865 9192c590b1431043e2a3da526e2fbbd3 238 Gene3D G3DSA:1.10.10.10 126 233 1.3E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS05060 3a2ca6d3bbb1d290d2498bc5dbe29e56 318 Pfam PF01420 Type I restriction modification DNA specificity domain 142 243 3.3E-5 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS05060 3a2ca6d3bbb1d290d2498bc5dbe29e56 318 Gene3D G3DSA:3.90.220.20 1 36 0.002 T 29-03-2018 THSYN_RS05060 3a2ca6d3bbb1d290d2498bc5dbe29e56 318 Gene3D G3DSA:3.90.220.20 63 228 2.0E-25 T 29-03-2018 THSYN_RS05060 3a2ca6d3bbb1d290d2498bc5dbe29e56 318 SUPERFAMILY SSF116734 61 280 8.5E-39 T 29-03-2018 THSYN_RS05060 3a2ca6d3bbb1d290d2498bc5dbe29e56 318 SUPERFAMILY SSF116734 2 60 1.08E-8 T 29-03-2018 THSYN_RS05060 3a2ca6d3bbb1d290d2498bc5dbe29e56 318 Gene3D G3DSA:1.10.287.1120 229 294 1.1E-4 T 29-03-2018 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SUPERFAMILY SSF55785 353 481 7.5E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 928 1042 1.8E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Pfam PF13185 GAF domain 511 655 5.9E-19 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Gene3D G3DSA:3.30.450.20 182 342 1.3E-22 T 29-03-2018 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Gene3D G3DSA:3.30.450.20 343 490 3.9E-27 T 29-03-2018 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SMART SM00448 1078 1191 1.5E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Pfam PF00989 PAS fold 667 776 1.4E-16 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Gene3D G3DSA:3.30.450.20 669 814 4.5E-29 T 29-03-2018 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Pfam PF08447 PAS fold 391 477 5.6E-19 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Pfam PF08447 PAS fold 228 311 1.6E-12 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SUPERFAMILY SSF55785 216 322 1.2E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SUPERFAMILY SSF55874 871 1040 1.31E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Gene3D G3DSA:3.30.450.40 491 668 2.3E-14 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Pfam PF01627 Hpt domain 1258 1329 1.7E-10 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1004 1022 7.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 987 997 7.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1028 1041 7.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 969 983 7.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SMART SM00086 737 779 5.1E-7 T 29-03-2018 IPR001610 PAC motif THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SMART SM00086 278 319 4.2E-6 T 29-03-2018 IPR001610 PAC motif THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SMART SM00086 441 483 2.4E-6 T 29-03-2018 IPR001610 PAC motif THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Gene3D G3DSA:1.10.287.130 815 878 2.2E-19 T 29-03-2018 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SMART SM00387 928 1044 1.6E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Gene3D G3DSA:3.40.50.2300 1064 1203 4.2E-39 T 29-03-2018 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SUPERFAMILY SSF52172 1077 1196 1.14E-35 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SUPERFAMILY SSF47384 803 883 4.71E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SUPERFAMILY SSF55781 513 668 2.35E-10 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Gene3D G3DSA:1.20.120.160 1242 1375 1.3E-14 T 29-03-2018 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 662 786 6.1E-23 T 29-03-2018 IPR000014 PAS domain THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 250 325 1.5E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 362 490 5.1E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SMART SM00065 511 665 2.4E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SUPERFAMILY SSF55785 671 777 4.54E-30 T 29-03-2018 IPR000014 PAS domain THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Pfam PF00072 Response regulator receiver domain 1081 1191 1.9E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 817 882 2.2E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Pfam PF07694 5TMR of 5TMR-LYT 35 186 7.6E-19 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SUPERFAMILY SSF47226 1174 1187 3.4E-14 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SUPERFAMILY SSF47226 1224 1327 3.4E-14 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SMART SM00388 817 882 1.3E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 Gene3D G3DSA:3.30.565.10 886 1053 6.7E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SMART SM00091 366 435 20.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS10440 04eabc4824e05c3493ca0c3cd6654007 1417 SMART SM00091 665 731 1.9E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS27570 653d91ade0089034034423222671c481 195 SMART SM00926 43 104 2.0E-23 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS27570 653d91ade0089034034423222671c481 195 SUPERFAMILY SSF53706 36 195 1.96E-54 T 29-03-2018 THSYN_RS27570 653d91ade0089034034423222671c481 195 Gene3D G3DSA:3.40.50.740 109 195 3.0E-11 T 29-03-2018 THSYN_RS27570 653d91ade0089034034423222671c481 195 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 45 103 1.4E-19 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS27570 653d91ade0089034034423222671c481 195 Gene3D G3DSA:2.20.25.90 36 108 1.8E-20 T 29-03-2018 THSYN_RS20795 c21d368520e2abe62fe46de6e5c1c388 118 Pfam PF12973 ChrR Cupin-like domain 26 108 1.9E-21 T 29-03-2018 IPR025979 ChrR-like cupin domain THSYN_RS20795 c21d368520e2abe62fe46de6e5c1c388 118 SUPERFAMILY SSF51182 23 110 6.62E-23 T 29-03-2018 IPR011051 RmlC-like cupin domain THSYN_RS20795 c21d368520e2abe62fe46de6e5c1c388 118 Gene3D G3DSA:2.60.120.10 4 117 9.9E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS14350 0e74a3c121590e7fb7f5c6964ad1a893 789 SUPERFAMILY SSF48452 511 695 9.99E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14350 0e74a3c121590e7fb7f5c6964ad1a893 789 Pfam PF13374 Tetratricopeptide repeat 629 656 0.011 T 29-03-2018 THSYN_RS14350 0e74a3c121590e7fb7f5c6964ad1a893 789 SUPERFAMILY SSF48452 414 534 1.23E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14350 0e74a3c121590e7fb7f5c6964ad1a893 789 Gene3D G3DSA:1.25.40.10 43 536 2.2E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14350 0e74a3c121590e7fb7f5c6964ad1a893 789 Gene3D G3DSA:1.25.40.10 642 703 0.0012 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14350 0e74a3c121590e7fb7f5c6964ad1a893 789 SMART SM00028 506 539 370.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14350 0e74a3c121590e7fb7f5c6964ad1a893 789 SMART SM00028 586 620 180.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14350 0e74a3c121590e7fb7f5c6964ad1a893 789 SMART SM00028 627 660 18.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14350 0e74a3c121590e7fb7f5c6964ad1a893 789 SMART SM00028 546 579 0.41 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14350 0e74a3c121590e7fb7f5c6964ad1a893 789 SMART SM00028 466 499 3.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14350 0e74a3c121590e7fb7f5c6964ad1a893 789 Pfam PF13424 Tetratricopeptide repeat 506 575 4.6E-9 T 29-03-2018 THSYN_RS14350 0e74a3c121590e7fb7f5c6964ad1a893 789 Gene3D G3DSA:1.10.150.200 537 591 3.4E-9 T 29-03-2018 THSYN_RS14350 0e74a3c121590e7fb7f5c6964ad1a893 789 Gene3D G3DSA:1.10.150.200 592 641 1.8E-6 T 29-03-2018 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 767 847 1.5E-25 T 29-03-2018 IPR019489 Clp ATPase, C-terminal THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 Gene3D G3DSA:3.40.50.300 158 343 8.1E-24 T 29-03-2018 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 676 694 8.1E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 602 620 8.1E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 709 723 8.1E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 647 665 8.1E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 SUPERFAMILY SSF81923 4 157 1.08E-38 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 632 650 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 SUPERFAMILY SSF52540 547 851 3.0E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 Gene3D G3DSA:1.10.8.60 767 861 1.8E-21 T 29-03-2018 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 SMART SM01086 767 856 4.5E-36 T 29-03-2018 IPR019489 Clp ATPase, C-terminal THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 Gene3D G3DSA:3.40.50.300 553 766 5.4E-53 T 29-03-2018 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 SUPERFAMILY SSF52540 160 546 3.58E-97 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 856 0.0 T 29-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 Gene3D G3DSA:1.10.8.60 344 548 1.1E-46 T 29-03-2018 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 96 146 1.0E-10 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 4.4E-11 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 Gene3D G3DSA:1.10.1780.10 1 152 8.3E-31 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 336 1.4E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 Pfam PF07724 AAA domain (Cdc48 subfamily) 597 761 5.4E-57 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 SMART SM00382 199 344 9.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS08745 152bcac579a311d3ee6deafa3773b6ce 866 SMART SM00382 598 747 2.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS13230 1fa8a7625b8f6bce4ba5cc95ac429095 570 Pfam PF00270 DEAD/DEAH box helicase 33 204 3.4E-44 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS13230 1fa8a7625b8f6bce4ba5cc95ac429095 570 SMART SM00487 28 234 1.5E-54 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS13230 1fa8a7625b8f6bce4ba5cc95ac429095 570 Pfam PF00271 Helicase conserved C-terminal domain 252 351 3.4E-27 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS13230 1fa8a7625b8f6bce4ba5cc95ac429095 570 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 163 171 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site THSYN_RS13230 1fa8a7625b8f6bce4ba5cc95ac429095 570 Gene3D G3DSA:3.40.50.300 237 556 8.5E-43 T 29-03-2018 THSYN_RS13230 1fa8a7625b8f6bce4ba5cc95ac429095 570 SUPERFAMILY SSF52540 84 362 4.36E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13230 1fa8a7625b8f6bce4ba5cc95ac429095 570 Gene3D G3DSA:3.40.50.300 7 236 7.9E-55 T 29-03-2018 THSYN_RS13230 1fa8a7625b8f6bce4ba5cc95ac429095 570 SMART SM00490 270 351 7.7E-31 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS13230 1fa8a7625b8f6bce4ba5cc95ac429095 570 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 8 389 52.394 T 29-03-2018 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 THSYN_RS28690 c4f854a3deef5266669296edc8c3fe33 238 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 14 224 1.3E-53 T 29-03-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 THSYN_RS28690 c4f854a3deef5266669296edc8c3fe33 238 SUPERFAMILY SSF100950 8 226 1.67E-60 T 29-03-2018 THSYN_RS28690 c4f854a3deef5266669296edc8c3fe33 238 Gene3D G3DSA:3.40.50.1360 1 223 7.8E-64 T 29-03-2018 THSYN_RS28690 c4f854a3deef5266669296edc8c3fe33 238 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 13 213 4.3E-61 T 29-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 THSYN_RS00905 d936b67c17bb91897ef6cb6ef91f37bd 552 SUPERFAMILY SSF55874 392 550 9.17E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00905 d936b67c17bb91897ef6cb6ef91f37bd 552 SMART SM00387 443 552 1.9E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00905 d936b67c17bb91897ef6cb6ef91f37bd 552 Gene3D G3DSA:1.10.287.130 327 391 1.1E-13 T 29-03-2018 THSYN_RS00905 d936b67c17bb91897ef6cb6ef91f37bd 552 SMART SM00388 335 401 8.7E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS00905 d936b67c17bb91897ef6cb6ef91f37bd 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 513 5.5E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00905 d936b67c17bb91897ef6cb6ef91f37bd 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 532 5.5E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00905 d936b67c17bb91897ef6cb6ef91f37bd 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 499 5.5E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00905 d936b67c17bb91897ef6cb6ef91f37bd 552 Pfam PF00512 His Kinase A (phospho-acceptor) domain 335 399 1.0E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS00905 d936b67c17bb91897ef6cb6ef91f37bd 552 Gene3D G3DSA:3.30.565.10 392 552 4.3E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00905 d936b67c17bb91897ef6cb6ef91f37bd 552 SUPERFAMILY SSF47384 325 398 1.59E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS00905 d936b67c17bb91897ef6cb6ef91f37bd 552 Gene3D G3DSA:3.30.450.20 200 326 8.4E-4 T 29-03-2018 THSYN_RS00905 d936b67c17bb91897ef6cb6ef91f37bd 552 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 444 550 1.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS23440 b35522eaf067ed0f4a84480ff3cec967 286 Gene3D G3DSA:3.20.10.10 134 283 1.7E-41 T 29-03-2018 THSYN_RS23440 b35522eaf067ed0f4a84480ff3cec967 286 Gene3D G3DSA:3.30.470.10 1 133 6.2E-28 T 29-03-2018 THSYN_RS23440 b35522eaf067ed0f4a84480ff3cec967 286 Pfam PF01063 Amino-transferase class IV 30 252 6.8E-45 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 THSYN_RS23440 b35522eaf067ed0f4a84480ff3cec967 286 ProSitePatterns PS00770 Aminotransferases class-IV signature. 179 208 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 THSYN_RS23440 b35522eaf067ed0f4a84480ff3cec967 286 SUPERFAMILY SSF56752 4 277 6.93E-76 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 THSYN_RS09260 aedbc322acefa3bbf536f6f07bea0621 1195 Gene3D G3DSA:3.60.21.10 7 369 1.2E-19 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS09260 aedbc322acefa3bbf536f6f07bea0621 1195 SUPERFAMILY SSF52540 429 658 3.18E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09260 aedbc322acefa3bbf536f6f07bea0621 1195 SUPERFAMILY SSF56436 921 1189 1.25E-60 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS09260 aedbc322acefa3bbf536f6f07bea0621 1195 SMART SM00382 431 605 0.0014 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS09260 aedbc322acefa3bbf536f6f07bea0621 1195 Pfam PF00149 Calcineurin-like phosphoesterase 14 259 2.3E-9 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS09260 aedbc322acefa3bbf536f6f07bea0621 1195 SUPERFAMILY SSF56300 154 310 4.0E-21 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS09260 aedbc322acefa3bbf536f6f07bea0621 1195 SUPERFAMILY SSF56300 13 108 4.0E-21 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS09260 aedbc322acefa3bbf536f6f07bea0621 1195 Pfam PF03781 Sulfatase-modifying factor enzyme 1 922 1188 7.8E-52 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS09260 aedbc322acefa3bbf536f6f07bea0621 1195 Gene3D G3DSA:3.90.1580.10 909 1195 3.6E-62 T 29-03-2018 THSYN_RS09260 aedbc322acefa3bbf536f6f07bea0621 1195 Gene3D G3DSA:3.40.50.300 370 617 8.0E-9 T 29-03-2018 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 Gene3D G3DSA:3.30.930.10 10 223 4.9E-59 T 29-03-2018 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 SUPERFAMILY SSF55681 407 478 4.27E-106 T 29-03-2018 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 SUPERFAMILY SSF55681 10 237 4.27E-106 T 29-03-2018 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 459 2.2E-47 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 571 41.719 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 SUPERFAMILY SSF52954 464 571 2.45E-29 T 29-03-2018 IPR004154 Anticodon-binding THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 Gene3D G3DSA:3.30.930.10 397 458 4.6E-9 T 29-03-2018 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 Pfam PF04073 Aminoacyl-tRNA editing domain 257 378 1.1E-22 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 Pfam PF03129 Anticodon binding domain 486 568 1.3E-15 T 29-03-2018 IPR004154 Anticodon-binding THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 567 7.0E-242 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 SUPERFAMILY SSF55826 218 390 1.27E-28 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 7.0E-19 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 7.0E-19 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 7.0E-19 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 7.0E-19 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 Gene3D G3DSA:3.40.50.800 459 573 2.5E-28 T 29-03-2018 IPR004154 Anticodon-binding THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 PIRSF PIRSF001535 1 574 3.6E-263 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THSYN_RS25920 23cef2002ced7598ebd89fe9df8d67fe 575 Gene3D G3DSA:3.90.960.10 241 389 9.1E-32 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THSYN_RS06160 f23451cd2eebee5e35a692a80c7656c9 825 Pfam PF03781 Sulfatase-modifying factor enzyme 1 625 822 2.9E-35 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS06160 f23451cd2eebee5e35a692a80c7656c9 825 SUPERFAMILY SSF56436 606 822 2.59E-46 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS06160 f23451cd2eebee5e35a692a80c7656c9 825 Gene3D G3DSA:3.90.1580.10 620 825 5.6E-41 T 29-03-2018 THSYN_RS06160 f23451cd2eebee5e35a692a80c7656c9 825 Gene3D G3DSA:3.40.50.300 120 299 3.3E-6 T 29-03-2018 THSYN_RS06160 f23451cd2eebee5e35a692a80c7656c9 825 SUPERFAMILY SSF52540 124 186 1.36E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06160 f23451cd2eebee5e35a692a80c7656c9 825 SUPERFAMILY SSF52540 220 378 1.36E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22395 985bf5d04f3cbe92357db6d13fab83a2 866 SUPERFAMILY SSF48452 339 548 4.3E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22395 985bf5d04f3cbe92357db6d13fab83a2 866 Gene3D G3DSA:1.25.40.10 324 727 1.4E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22395 985bf5d04f3cbe92357db6d13fab83a2 866 Gene3D G3DSA:1.25.40.10 11 222 1.1E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS05715 5703065c0db0b29e2f738fa71e33206d 125 SUPERFAMILY SSF48300 4 61 2.88E-16 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS05715 5703065c0db0b29e2f738fa71e33206d 125 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 125 25.041 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS05715 5703065c0db0b29e2f738fa71e33206d 125 Gene3D G3DSA:3.30.1390.10 55 125 1.8E-31 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THSYN_RS05715 5703065c0db0b29e2f738fa71e33206d 125 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 60 125 2.0E-20 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS05715 5703065c0db0b29e2f738fa71e33206d 125 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 125 6.1E-48 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS05715 5703065c0db0b29e2f738fa71e33206d 125 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 59 125 1.0E-31 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS05715 5703065c0db0b29e2f738fa71e33206d 125 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 48 1.1E-18 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS05715 5703065c0db0b29e2f738fa71e33206d 125 SUPERFAMILY SSF54736 54 125 1.92E-25 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THSYN_RS05715 5703065c0db0b29e2f738fa71e33206d 125 Gene3D G3DSA:1.20.5.710 3 54 2.7E-15 T 29-03-2018 THSYN_RS16820 19586f7e5ccd4f6fcb5691613698f0ee 248 SUPERFAMILY SSF52172 1 123 5.69E-35 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS16820 19586f7e5ccd4f6fcb5691613698f0ee 248 Gene3D G3DSA:2.20.25.10 210 244 2.6E-4 T 29-03-2018 THSYN_RS16820 19586f7e5ccd4f6fcb5691613698f0ee 248 Pfam PF00072 Response regulator receiver domain 3 113 2.9E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS16820 19586f7e5ccd4f6fcb5691613698f0ee 248 Gene3D G3DSA:2.40.50.40 139 205 6.0E-12 T 29-03-2018 THSYN_RS16820 19586f7e5ccd4f6fcb5691613698f0ee 248 SMART SM00448 1 113 9.9E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS16820 19586f7e5ccd4f6fcb5691613698f0ee 248 SMART SM00850 147 244 2.2E-28 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 THSYN_RS16820 19586f7e5ccd4f6fcb5691613698f0ee 248 Pfam PF04397 LytTr DNA-binding domain 151 243 5.9E-22 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 THSYN_RS16820 19586f7e5ccd4f6fcb5691613698f0ee 248 Gene3D G3DSA:3.40.50.2300 1 133 4.9E-33 T 29-03-2018 THSYN_RS26950 8cb7d71ed9dc39eca83d077629f0e3cc 176 Gene3D G3DSA:3.30.70.20 119 141 8.7E-11 T 29-03-2018 THSYN_RS26950 8cb7d71ed9dc39eca83d077629f0e3cc 176 Gene3D G3DSA:3.30.70.20 142 175 1.8E-4 T 29-03-2018 THSYN_RS26950 8cb7d71ed9dc39eca83d077629f0e3cc 176 Pfam PF04060 Putative Fe-S cluster 41 73 3.5E-10 T 29-03-2018 IPR007202 4Fe-4S domain GO:0051536 THSYN_RS26950 8cb7d71ed9dc39eca83d077629f0e3cc 176 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 140 151 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS26950 8cb7d71ed9dc39eca83d077629f0e3cc 176 Gene3D G3DSA:3.30.70.20 24 118 1.9E-7 T 29-03-2018 THSYN_RS26950 8cb7d71ed9dc39eca83d077629f0e3cc 176 Pfam PF14697 4Fe-4S dicluster domain 103 157 2.6E-12 T 29-03-2018 THSYN_RS26950 8cb7d71ed9dc39eca83d077629f0e3cc 176 PIRSF PIRSF005784 1 176 3.1E-55 T 29-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 THSYN_RS26950 8cb7d71ed9dc39eca83d077629f0e3cc 176 SUPERFAMILY SSF54862 39 169 1.26E-25 T 29-03-2018 THSYN_RS26950 8cb7d71ed9dc39eca83d077629f0e3cc 176 Hamap MF_00463 Electron transport complex subunit RsxB [rsxB]. 1 175 34.454 T 29-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 THSYN_RS26950 8cb7d71ed9dc39eca83d077629f0e3cc 176 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 3 173 4.8E-54 T 29-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 THSYN_RS08870 fc6ce43df7276aa73e7b3c59795e442d 171 Pfam PF05751 FixH 18 166 6.6E-30 T 29-03-2018 IPR008620 Nitrogen fixation protein FixH THSYN_RS08870 fc6ce43df7276aa73e7b3c59795e442d 171 Gene3D G3DSA:2.60.40.10 69 162 9.7E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS05965 515f115a7970561449a5b5e02ec8cbee 294 Gene3D G3DSA:3.90.550.10 4 291 2.1E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS05965 515f115a7970561449a5b5e02ec8cbee 294 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 4 288 2.6E-148 T 29-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 THSYN_RS05965 515f115a7970561449a5b5e02ec8cbee 294 Pfam PF00483 Nucleotidyl transferase 4 240 2.8E-67 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THSYN_RS05965 515f115a7970561449a5b5e02ec8cbee 294 SUPERFAMILY SSF53448 2 288 7.43E-89 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 SUPERFAMILY SSF52922 489 614 1.57E-31 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 7 617 45.722 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 Pfam PF02780 Transketolase, C-terminal domain 492 608 2.2E-26 T 29-03-2018 IPR033248 Transketolase, C-terminal domain THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 SMART SM00861 316 480 1.4E-67 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 SUPERFAMILY SSF52518 3 196 9.98E-83 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 SUPERFAMILY SSF52518 240 378 9.98E-83 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 Gene3D G3DSA:3.40.50.920 492 618 4.3E-34 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 8 279 1.0E-122 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 Pfam PF02779 Transketolase, pyrimidine binding domain 316 477 9.6E-37 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 Gene3D G3DSA:3.40.50.970 1 294 1.8E-83 T 29-03-2018 THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 Gene3D G3DSA:3.40.50.970 295 483 8.1E-63 T 29-03-2018 THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 ProSitePatterns PS00801 Transketolase signature 1. 33 52 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 9 616 1.7E-263 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS13345 f61e73ef850c74d0cad3a45e2f26bbc2 633 SUPERFAMILY SSF52518 314 501 6.48E-59 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS11355 fd487922644151a0b806df85189cc9dc 132 Pfam PF01850 PIN domain 2 121 5.0E-14 T 29-03-2018 IPR002716 PIN domain THSYN_RS11355 fd487922644151a0b806df85189cc9dc 132 Gene3D G3DSA:3.40.50.1010 1 131 6.2E-18 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS11355 fd487922644151a0b806df85189cc9dc 132 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 130 9.792 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS11355 fd487922644151a0b806df85189cc9dc 132 SUPERFAMILY SSF88723 1 130 3.64E-20 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 SUPERFAMILY SSF54980 389 465 5.04E-15 T 29-03-2018 IPR035647 EF-G domain III/V-like THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 SUPERFAMILY SSF50447 258 388 7.57E-29 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 Gene3D G3DSA:3.40.50.300 79 268 9.7E-28 T 29-03-2018 THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 158 3.1E-21 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 Pfam PF00009 Elongation factor Tu GTP binding domain 10 274 2.4E-49 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 1 525 3.0E-252 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 SUPERFAMILY SSF52540 8 274 5.82E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 Gene3D G3DSA:3.30.70.870 386 461 2.5E-7 T 29-03-2018 THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 Gene3D G3DSA:2.40.30.10 269 381 5.2E-20 T 29-03-2018 THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 PRINTS PR00315 GTP-binding elongation factor signature 83 93 2.8E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 PRINTS PR00315 GTP-binding elongation factor signature 99 110 2.8E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 PRINTS PR00315 GTP-binding elongation factor signature 63 71 2.8E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 PRINTS PR00315 GTP-binding elongation factor signature 13 26 2.8E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 PRINTS PR00315 GTP-binding elongation factor signature 135 144 2.8E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 Pfam PF16658 Class II release factor RF3, C-terminal domain 384 509 9.4E-43 T 29-03-2018 IPR032090 Peptide chain release factor 3, C-terminal THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 56 71 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 Gene3D G3DSA:3.40.50.300 1 78 1.2E-7 T 29-03-2018 THSYN_RS12935 dd8a6e0ee5b47e9bef1ef2ab6729cbbb 526 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 2 524 52.058 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 THSYN_RS03295 df9444cfc7aae736d9f9371995d2d3f1 387 Gene3D G3DSA:1.10.10.10 293 386 2.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS03295 df9444cfc7aae736d9f9371995d2d3f1 387 Pfam PF02661 Fic/DOC family 130 234 1.4E-21 T 29-03-2018 IPR003812 Fido domain THSYN_RS03295 df9444cfc7aae736d9f9371995d2d3f1 387 SUPERFAMILY SSF140931 106 300 4.05E-45 T 29-03-2018 IPR003812 Fido domain THSYN_RS03295 df9444cfc7aae736d9f9371995d2d3f1 387 Gene3D G3DSA:1.10.3290.10 40 292 6.5E-57 T 29-03-2018 IPR003812 Fido domain THSYN_RS03295 df9444cfc7aae736d9f9371995d2d3f1 387 PIRSF PIRSF038925 14 383 5.6E-110 T 29-03-2018 IPR026287 Adenosine monophosphate-protein transferase THSYN_RS03295 df9444cfc7aae736d9f9371995d2d3f1 387 Pfam PF13784 Fic/DOC family N-terminal 42 121 6.0E-26 T 29-03-2018 IPR025758 Fic/DOC N-terminal THSYN_RS19400 1dc6170bb795316b5c8eef2a70608ecb 558 Gene3D G3DSA:1.10.10.60 6 37 2.5E-4 T 29-03-2018 THSYN_RS19400 1dc6170bb795316b5c8eef2a70608ecb 558 Gene3D G3DSA:1.10.10.10 38 209 9.2E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS01310 1dc6170bb795316b5c8eef2a70608ecb 558 Gene3D G3DSA:1.10.10.60 6 37 2.5E-4 T 29-03-2018 THSYN_RS01310 1dc6170bb795316b5c8eef2a70608ecb 558 Gene3D G3DSA:1.10.10.10 38 209 9.2E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25940 1dc6170bb795316b5c8eef2a70608ecb 558 Gene3D G3DSA:1.10.10.60 6 37 2.5E-4 T 29-03-2018 THSYN_RS25940 1dc6170bb795316b5c8eef2a70608ecb 558 Gene3D G3DSA:1.10.10.10 38 209 9.2E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS09430 634dec374816b6f909fd78c04ca18093 307 SUPERFAMILY SSF88697 250 307 7.95E-13 T 29-03-2018 IPR015947 PUA-like domain THSYN_RS09430 634dec374816b6f909fd78c04ca18093 307 SUPERFAMILY SSF55120 12 234 3.74E-79 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS09430 634dec374816b6f909fd78c04ca18093 307 Gene3D G3DSA:3.30.2350.10 11 232 2.2E-78 T 29-03-2018 THSYN_RS09430 634dec374816b6f909fd78c04ca18093 307 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 183 247 3.9E-19 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 THSYN_RS09430 634dec374816b6f909fd78c04ca18093 307 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 34 182 1.8E-57 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 THSYN_RS09430 634dec374816b6f909fd78c04ca18093 307 Gene3D G3DSA:2.30.130.10 249 307 5.7E-20 T 29-03-2018 IPR002478 PUA domain GO:0003723 THSYN_RS09430 634dec374816b6f909fd78c04ca18093 307 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 251 307 3.5E-21 T 29-03-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS09430 634dec374816b6f909fd78c04ca18093 307 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 13 211 9.1E-79 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS09430 634dec374816b6f909fd78c04ca18093 307 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 12 307 19.715 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 Gene3D G3DSA:3.30.450.20 188 322 3.2E-24 T 29-03-2018 THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 SUPERFAMILY SSF55785 174 305 5.06E-21 T 29-03-2018 IPR000014 PAS domain THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 SMART SM00267 314 486 1.4E-69 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 321 483 8.9E-46 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 Gene3D G3DSA:3.30.450.20 47 187 3.4E-14 T 29-03-2018 THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 Gene3D G3DSA:3.20.20.450 490 756 6.5E-99 T 29-03-2018 IPR001633 EAL domain THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 Pfam PF00563 EAL domain 503 738 8.6E-70 T 29-03-2018 IPR001633 EAL domain THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 SUPERFAMILY SSF55073 330 488 1.33E-52 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 Pfam PF13188 PAS domain 67 108 0.11 T 29-03-2018 IPR000014 PAS domain THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 SMART SM00052 496 743 5.3E-113 T 29-03-2018 IPR001633 EAL domain THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 187 313 9.5E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 SUPERFAMILY SSF141868 502 750 3.92E-87 T 29-03-2018 IPR001633 EAL domain THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 SUPERFAMILY SSF55785 49 157 2.97E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 Gene3D G3DSA:3.30.70.270 323 489 3.9E-65 T 29-03-2018 THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 Pfam PF00990 Diguanylate cyclase, GGDEF domain 325 481 2.4E-53 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 Pfam PF08448 PAS fold 196 306 3.4E-13 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 SMART SM00091 62 128 4.7 T 29-03-2018 IPR000014 PAS domain THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 SMART SM00091 189 255 0.32 T 29-03-2018 IPR000014 PAS domain THSYN_RS07020 1f354e533d7bfcb62551390c22194aae 763 SMART SM00086 265 307 0.005 T 29-03-2018 IPR001610 PAC motif THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 SUPERFAMILY SSF52540 348 585 6.83E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 431 446 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 Pfam PF00158 Sigma-54 interaction domain 348 511 4.7E-63 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 Gene3D G3DSA:1.10.8.60 515 580 4.6E-15 T 29-03-2018 THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 Pfam PF01590 GAF domain 75 208 6.3E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 SMART SM00382 364 507 1.2E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 Pfam PF02954 Bacterial regulatory protein, Fis family 610 647 2.5E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 SUPERFAMILY SSF55781 71 191 2.04E-8 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 Gene3D G3DSA:3.30.450.20 228 325 6.7E-4 T 29-03-2018 THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 Gene3D G3DSA:1.10.10.60 581 650 1.2E-15 T 29-03-2018 THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 613 630 3.6E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 630 650 3.6E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 Gene3D G3DSA:3.40.50.300 341 514 2.5E-22 T 29-03-2018 THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 555 564 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 SUPERFAMILY SSF46689 555 650 1.41E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 Gene3D G3DSA:3.30.450.40 130 212 9.2E-5 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS33150 e9c54b3213f8da5d06211195f1b20a7d 653 Gene3D G3DSA:3.30.450.40 68 129 0.35 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS13985 b9ab72fb1aa5f564fa9a19e67ee05e31 113 SUPERFAMILY SSF47413 6 69 4.83E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS13985 b9ab72fb1aa5f564fa9a19e67ee05e31 113 Pfam PF01381 Helix-turn-helix 14 68 9.7E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS13985 b9ab72fb1aa5f564fa9a19e67ee05e31 113 Gene3D G3DSA:1.10.260.40 1 83 5.6E-18 T 29-03-2018 THSYN_RS13985 b9ab72fb1aa5f564fa9a19e67ee05e31 113 SMART SM00530 13 68 1.6E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS13025 48815cb8c75cc5ddc1a3720635fd29d1 241 Pfam PF01618 MotA/TolQ/ExbB proton channel family 96 210 6.0E-30 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 THSYN_RS23135 83ff51aec9ff952a2cabb5ae97f77d34 314 Gene3D G3DSA:3.90.550.10 2 227 6.6E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS23135 83ff51aec9ff952a2cabb5ae97f77d34 314 Pfam PF00535 Glycosyl transferase family 2 5 156 4.2E-30 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS23135 83ff51aec9ff952a2cabb5ae97f77d34 314 SUPERFAMILY SSF53448 2 252 5.63E-39 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS04045 e0cc3da78f9116a2c380b03201dd7227 312 SUPERFAMILY SSF101478 20 292 4.05E-65 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 THSYN_RS04045 e0cc3da78f9116a2c380b03201dd7227 312 Pfam PF03747 ADP-ribosylglycohydrolase 26 282 2.1E-52 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 THSYN_RS04045 e0cc3da78f9116a2c380b03201dd7227 312 TIGRFAM TIGR02662 dinitro_DRAG: ADP-ribosyl-[dinitrogen reductase] hydrolase 20 307 5.3E-120 T 29-03-2018 IPR013479 ADP-ribosyl-dinitrogen reductase hydrolase THSYN_RS04045 e0cc3da78f9116a2c380b03201dd7227 312 Gene3D G3DSA:1.10.4080.10 13 308 1.4E-66 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 THSYN_RS09095 454a9df50660c347f681e1a4a640bf76 154 PIRSF PIRSF010312 2 154 5.3E-43 T 29-03-2018 IPR016568 Sulphur oxidation, SoxY THSYN_RS09095 454a9df50660c347f681e1a4a640bf76 154 Gene3D G3DSA:2.60.40.730 54 148 6.7E-7 T 29-03-2018 THSYN_RS09095 454a9df50660c347f681e1a4a640bf76 154 Pfam PF13501 Sulfur oxidation protein SoxY 49 152 1.4E-32 T 29-03-2018 IPR032711 Ig-like SoxY domain THSYN_RS09095 454a9df50660c347f681e1a4a640bf76 154 TIGRFAM TIGR04488 SoxY_true_GGCGG: thiosulfate oxidation carrier protein SoxY 5 154 3.2E-47 T 29-03-2018 IPR016568 Sulphur oxidation, SoxY THSYN_RS21700 3467b5c4a953f6f736664d75a6d10541 82 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 39 6.9E-8 T 29-03-2018 THSYN_RS21700 3467b5c4a953f6f736664d75a6d10541 82 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 41 5.8E-12 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS21700 3467b5c4a953f6f736664d75a6d10541 82 SUPERFAMILY SSF143120 1 40 8.11E-9 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS21700 3467b5c4a953f6f736664d75a6d10541 82 Gene3D G3DSA:3.40.1620.10 1 39 7.6E-15 T 29-03-2018 THSYN_RS20690 62aebbad104c753ce23565d45a4f35f3 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 224 1.1E-75 T 29-03-2018 IPR001405 RadC protein THSYN_RS20690 62aebbad104c753ce23565d45a4f35f3 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 29-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site THSYN_RS20690 62aebbad104c753ce23565d45a4f35f3 224 Gene3D G3DSA:3.40.140.10 99 224 1.4E-45 T 29-03-2018 THSYN_RS20690 62aebbad104c753ce23565d45a4f35f3 224 SUPERFAMILY SSF47781 19 91 8.9E-11 T 29-03-2018 IPR010994 RuvA domain 2-like THSYN_RS20690 62aebbad104c753ce23565d45a4f35f3 224 SUPERFAMILY SSF102712 111 193 8.76E-7 T 29-03-2018 THSYN_RS20690 62aebbad104c753ce23565d45a4f35f3 224 Pfam PF04002 RadC-like JAB domain 103 222 1.8E-43 T 29-03-2018 IPR025657 RadC-like JAB domain THSYN_RS02305 dd9a8a25f9e0605f98c84a0c612f3667 182 Gene3D G3DSA:3.90.80.10 3 180 8.6E-51 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THSYN_RS02305 dd9a8a25f9e0605f98c84a0c612f3667 182 Pfam PF00719 Inorganic pyrophosphatase 18 172 3.5E-52 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THSYN_RS02305 dd9a8a25f9e0605f98c84a0c612f3667 182 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 36.407 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THSYN_RS02305 dd9a8a25f9e0605f98c84a0c612f3667 182 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THSYN_RS02305 dd9a8a25f9e0605f98c84a0c612f3667 182 SUPERFAMILY SSF50324 4 174 1.57E-65 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THSYN_RS22200 bc46007b236fb0d5133f05389b0db4c5 363 Gene3D G3DSA:4.10.1250.10 232 273 4.7E-17 T 29-03-2018 THSYN_RS22200 bc46007b236fb0d5133f05389b0db4c5 363 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 254 6.6E-87 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal THSYN_RS22200 bc46007b236fb0d5133f05389b0db4c5 363 Gene3D G3DSA:3.30.1360.120 121 231 2.2E-27 T 29-03-2018 THSYN_RS22200 bc46007b236fb0d5133f05389b0db4c5 363 Gene3D G3DSA:3.30.1360.120 3 120 1.8E-30 T 29-03-2018 THSYN_RS22200 bc46007b236fb0d5133f05389b0db4c5 363 PIRSF PIRSF006487 1 362 7.6E-82 T 29-03-2018 THSYN_RS22200 bc46007b236fb0d5133f05389b0db4c5 363 Gene3D G3DSA:2.40.30.110 278 363 3.0E-22 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THSYN_RS22200 bc46007b236fb0d5133f05389b0db4c5 363 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 262 350 2.0E-19 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THSYN_RS22200 bc46007b236fb0d5133f05389b0db4c5 363 SUPERFAMILY SSF103025 4 275 4.24E-91 T 29-03-2018 THSYN_RS22200 bc46007b236fb0d5133f05389b0db4c5 363 SUPERFAMILY SSF101790 272 358 1.06E-23 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain THSYN_RS22200 bc46007b236fb0d5133f05389b0db4c5 363 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 356 2.0E-128 T 29-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 THSYN_RS22200 bc46007b236fb0d5133f05389b0db4c5 363 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 356 44.95 T 29-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THSYN_RS04265 8b992423e64f45e0152c5daf32393321 485 Gene3D G3DSA:3.50.50.60 147 285 7.7E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS04265 8b992423e64f45e0152c5daf32393321 485 SUPERFAMILY SSF51905 191 298 1.01E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS04265 8b992423e64f45e0152c5daf32393321 485 SUPERFAMILY SSF51905 328 396 1.01E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS04265 8b992423e64f45e0152c5daf32393321 485 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 316 3.9E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS04265 8b992423e64f45e0152c5daf32393321 485 Gene3D G3DSA:3.50.50.60 3 146 1.8E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS04265 8b992423e64f45e0152c5daf32393321 485 SUPERFAMILY SSF51905 2 196 1.86E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS07540 b7e8c289945071095548010564bbc664 104 Gene3D G3DSA:1.10.10.60 11 59 6.8E-4 T 29-03-2018 THSYN_RS07540 b7e8c289945071095548010564bbc664 104 Pfam PF13560 Helix-turn-helix domain 47 92 9.3E-12 T 29-03-2018 THSYN_RS07540 b7e8c289945071095548010564bbc664 104 SUPERFAMILY SSF47413 45 89 1.95E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS07540 b7e8c289945071095548010564bbc664 104 SMART SM00530 44 101 7.6E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS07540 b7e8c289945071095548010564bbc664 104 Gene3D G3DSA:1.10.260.40 60 104 1.8E-15 T 29-03-2018 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Gene3D G3DSA:1.25.40.10 716 785 4.8E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SUPERFAMILY SSF48452 838 1126 3.32E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Gene3D G3DSA:1.25.40.10 662 715 1.2E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Pfam PF14559 Tetratricopeptide repeat 572 628 1.0E-6 T 29-03-2018 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Pfam PF14559 Tetratricopeptide repeat 1082 1148 2.4E-8 T 29-03-2018 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SUPERFAMILY SSF48452 628 820 2.79E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Gene3D G3DSA:1.25.40.120 786 941 1.2E-12 T 29-03-2018 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SUPERFAMILY SSF48452 364 532 1.22E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Pfam PF13432 Tetratricopeptide repeat 465 526 0.001 T 29-03-2018 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Pfam PF13432 Tetratricopeptide repeat 364 425 3.1E-5 T 29-03-2018 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Pfam PF13432 Tetratricopeptide repeat 636 697 2.2E-4 T 29-03-2018 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Pfam PF13432 Tetratricopeptide repeat 710 765 0.0027 T 29-03-2018 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Gene3D G3DSA:1.25.40.10 1023 1136 2.2E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SMART SM00028 664 697 43.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SMART SM00028 494 527 71.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SMART SM00028 1037 1069 210.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SMART SM00028 1003 1036 72.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SMART SM00028 358 391 16.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SMART SM00028 834 867 360.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SMART SM00028 732 765 3.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SMART SM00028 392 425 260.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SMART SM00028 698 731 250.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 TIGRFAM TIGR02917 PEP_TPR_lipo: putative PEP-CTERM system TPR-repeat lipoprotein 256 1131 5.5E-107 T 29-03-2018 IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Gene3D G3DSA:1.25.40.10 355 563 2.7E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SUPERFAMILY SSF48452 260 343 9.63E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Gene3D G3DSA:1.25.40.10 942 1022 6.0E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 SUPERFAMILY SSF48452 491 629 1.9E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Gene3D G3DSA:1.25.40.10 240 349 6.7E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18000 c28e1ca07672dd41d43eaa1fbdd90910 1151 Gene3D G3DSA:1.25.40.10 564 661 7.9E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS17465 09f13c31372e97aea40871c278df108a 269 SUPERFAMILY SSF50494 36 262 8.75E-33 T 29-03-2018 IPR009003 Peptidase S1, PA clan THSYN_RS17465 09f13c31372e97aea40871c278df108a 269 Gene3D G3DSA:2.40.10.10 145 266 2.0E-17 T 29-03-2018 THSYN_RS17465 09f13c31372e97aea40871c278df108a 269 Gene3D G3DSA:2.40.10.10 31 144 6.4E-19 T 29-03-2018 THSYN_RS17465 09f13c31372e97aea40871c278df108a 269 Pfam PF13365 Trypsin-like peptidase domain 65 227 1.6E-23 T 29-03-2018 THSYN_RS25135 e6a6a9e145a2af77d3cff54152e1dd04 379 Gene3D G3DSA:3.90.1150.10 240 375 2.2E-35 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS25135 e6a6a9e145a2af77d3cff54152e1dd04 379 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 17 370 7.7E-127 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THSYN_RS25135 e6a6a9e145a2af77d3cff54152e1dd04 379 Gene3D G3DSA:3.40.640.10 2 239 6.2E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS25135 e6a6a9e145a2af77d3cff54152e1dd04 379 PIRSF PIRSF000390 6 375 1.1E-107 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THSYN_RS25135 e6a6a9e145a2af77d3cff54152e1dd04 379 SUPERFAMILY SSF53383 14 372 1.57E-113 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS16500 f3ad3245e6167f99d2788291452ee6d6 391 Gene3D G3DSA:3.10.400.10 3 184 1.6E-59 T 29-03-2018 THSYN_RS16500 f3ad3245e6167f99d2788291452ee6d6 391 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 28 387 43.38 T 29-03-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 THSYN_RS16500 f3ad3245e6167f99d2788291452ee6d6 391 SUPERFAMILY SSF52374 173 387 3.08E-75 T 29-03-2018 THSYN_RS16500 f3ad3245e6167f99d2788291452ee6d6 391 Pfam PF14306 PUA-like domain 5 163 2.1E-52 T 29-03-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 THSYN_RS16500 f3ad3245e6167f99d2788291452ee6d6 391 SUPERFAMILY SSF88697 4 168 1.69E-47 T 29-03-2018 IPR015947 PUA-like domain THSYN_RS16500 f3ad3245e6167f99d2788291452ee6d6 391 Gene3D G3DSA:3.40.50.620 185 391 6.0E-82 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS16500 f3ad3245e6167f99d2788291452ee6d6 391 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 6 383 3.6E-115 T 29-03-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 THSYN_RS16500 f3ad3245e6167f99d2788291452ee6d6 391 Pfam PF01747 ATP-sulfurylase 174 384 5.9E-81 T 29-03-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 THSYN_RS09520 8c687b1c2610aa7d7ec735625129847a 468 SUPERFAMILY SSF50494 4 154 2.44E-10 T 29-03-2018 IPR009003 Peptidase S1, PA clan THSYN_RS09520 8c687b1c2610aa7d7ec735625129847a 468 Gene3D G3DSA:2.40.10.10 13 103 9.0E-6 T 29-03-2018 THSYN_RS00320 7971840024ac838e85e4e9b6e7d56087 129 Gene3D G3DSA:3.30.1130.10 3 126 1.1E-32 T 29-03-2018 THSYN_RS00320 7971840024ac838e85e4e9b6e7d56087 129 SUPERFAMILY SSF55620 5 112 1.93E-28 T 29-03-2018 THSYN_RS00320 7971840024ac838e85e4e9b6e7d56087 129 PIRSF PIRSF027377 2 124 2.7E-54 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 THSYN_RS00320 7971840024ac838e85e4e9b6e7d56087 129 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 129 50.703 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 THSYN_RS00320 7971840024ac838e85e4e9b6e7d56087 129 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 8 116 3.5E-53 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 THSYN_RS00320 7971840024ac838e85e4e9b6e7d56087 129 Pfam PF14489 QueF-like protein 40 117 1.2E-32 T 29-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 THSYN_RS10915 4a6945b6712906d85d81f44b030bb72e 410 Gene3D G3DSA:3.40.50.1100 214 408 1.1E-39 T 29-03-2018 THSYN_RS10915 4a6945b6712906d85d81f44b030bb72e 410 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 22 404 1.1E-190 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THSYN_RS10915 4a6945b6712906d85d81f44b030bb72e 410 Gene3D G3DSA:3.40.50.1100 24 213 7.2E-45 T 29-03-2018 THSYN_RS10915 4a6945b6712906d85d81f44b030bb72e 410 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 68 393 3.3E-44 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THSYN_RS10915 4a6945b6712906d85d81f44b030bb72e 410 SUPERFAMILY SSF53686 18 403 1.7E-148 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THSYN_RS10915 4a6945b6712906d85d81f44b030bb72e 410 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 96 110 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THSYN_RS10915 4a6945b6712906d85d81f44b030bb72e 410 PIRSF PIRSF001413 12 409 2.0E-163 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THSYN_RS10915 4a6945b6712906d85d81f44b030bb72e 410 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 17 406 52.679 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THSYN_RS00850 22f77484616872cbd9284fa712523ca2 471 Gene3D G3DSA:3.30.70.20 361 383 0.28 T 29-03-2018 THSYN_RS00850 22f77484616872cbd9284fa712523ca2 471 Gene3D G3DSA:3.30.70.20 280 316 0.0024 T 29-03-2018 THSYN_RS00850 22f77484616872cbd9284fa712523ca2 471 SUPERFAMILY SSF54862 287 390 5.44E-15 T 29-03-2018 THSYN_RS00850 22f77484616872cbd9284fa712523ca2 471 Pfam PF02589 LUD domain 65 290 3.0E-53 T 29-03-2018 IPR003741 LUD domain THSYN_RS00850 22f77484616872cbd9284fa712523ca2 471 Pfam PF11870 Domain of unknown function (DUF3390) 381 463 2.3E-17 T 29-03-2018 IPR024569 4Fe-4S binding protein, C-terminal THSYN_RS00850 22f77484616872cbd9284fa712523ca2 471 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 309 320 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS00850 22f77484616872cbd9284fa712523ca2 471 Gene3D G3DSA:3.40.50.10420 131 279 3.7E-45 T 29-03-2018 THSYN_RS00850 22f77484616872cbd9284fa712523ca2 471 Gene3D G3DSA:3.40.50.10420 60 130 5.9E-8 T 29-03-2018 THSYN_RS00850 22f77484616872cbd9284fa712523ca2 471 SUPERFAMILY SSF100950 130 291 4.6E-41 T 29-03-2018 THSYN_RS00850 22f77484616872cbd9284fa712523ca2 471 SUPERFAMILY SSF100950 60 84 4.6E-41 T 29-03-2018 THSYN_RS00850 22f77484616872cbd9284fa712523ca2 471 Gene3D G3DSA:3.30.70.20 317 360 6.7E-6 T 29-03-2018 THSYN_RS00850 22f77484616872cbd9284fa712523ca2 471 Pfam PF13183 4Fe-4S dicluster domain 307 373 1.7E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS21990 68a149c13f64d32b17e44347604cf7da 365 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 146 174 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 THSYN_RS21990 68a149c13f64d32b17e44347604cf7da 365 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 21 342 36.309 T 29-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 THSYN_RS21990 68a149c13f64d32b17e44347604cf7da 365 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 24 345 1.5E-107 T 29-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 THSYN_RS21990 68a149c13f64d32b17e44347604cf7da 365 SUPERFAMILY SSF51161 51 333 2.62E-76 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS21990 68a149c13f64d32b17e44347604cf7da 365 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 39 104 4.5E-18 T 29-03-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 THSYN_RS21990 68a149c13f64d32b17e44347604cf7da 365 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 144 176 1.4E-6 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS21990 68a149c13f64d32b17e44347604cf7da 365 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 238 272 1.9E-5 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS21990 68a149c13f64d32b17e44347604cf7da 365 Gene3D G3DSA:2.160.10.10 113 139 0.0016 T 29-03-2018 THSYN_RS21990 68a149c13f64d32b17e44347604cf7da 365 Gene3D G3DSA:2.160.10.10 140 326 1.1E-48 T 29-03-2018 THSYN_RS13720 c8c522e0583a6394e27c85dc2eff1a56 348 Pfam PF02445 Quinolinate synthetase A protein 36 342 1.2E-101 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 THSYN_RS13720 c8c522e0583a6394e27c85dc2eff1a56 348 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 30 343 1.3E-108 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 THSYN_RS13720 c8c522e0583a6394e27c85dc2eff1a56 348 Gene3D G3DSA:3.40.50.10800 27 114 5.4E-17 T 29-03-2018 THSYN_RS13720 c8c522e0583a6394e27c85dc2eff1a56 348 Gene3D G3DSA:3.40.50.10800 214 325 2.3E-29 T 29-03-2018 THSYN_RS13720 c8c522e0583a6394e27c85dc2eff1a56 348 Gene3D G3DSA:3.40.50.10800 119 213 1.5E-20 T 29-03-2018 THSYN_RS13720 c8c522e0583a6394e27c85dc2eff1a56 348 SUPERFAMILY SSF142754 33 343 4.45E-106 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 SUPERFAMILY SSF54782 219 306 4.84E-28 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 Gene3D G3DSA:3.30.160.40 220 303 1.6E-25 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 211 3.3E-78 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 PIRSF PIRSF001438 1 308 4.1E-121 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 Gene3D G3DSA:3.40.190.10 1 105 8.5E-45 T 29-03-2018 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 PRINTS PR00151 Porphobilinogen deaminase signature 123 140 1.4E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 1.4E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 PRINTS PR00151 Porphobilinogen deaminase signature 142 159 1.4E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 PRINTS PR00151 Porphobilinogen deaminase signature 44 64 1.4E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 PRINTS PR00151 Porphobilinogen deaminase signature 75 94 1.4E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 296 3.5E-112 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 225 294 4.4E-21 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 Gene3D G3DSA:3.40.190.10 106 198 2.6E-37 T 29-03-2018 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 SUPERFAMILY SSF53850 4 217 6.86E-84 T 29-03-2018 THSYN_RS05640 0df6471e9fcd879934c7cba0476af279 308 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 296 39.636 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS19710 ea2b990a2de9f2bfb89eb2f2bddf8819 437 SUPERFAMILY SSF69304 160 434 8.89E-60 T 29-03-2018 THSYN_RS19710 ea2b990a2de9f2bfb89eb2f2bddf8819 437 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 24 433 3.4E-151 T 29-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 THSYN_RS19710 ea2b990a2de9f2bfb89eb2f2bddf8819 437 Pfam PF04052 TolB amino-terminal domain 31 134 1.0E-27 T 29-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 THSYN_RS19710 ea2b990a2de9f2bfb89eb2f2bddf8819 437 Pfam PF07676 WD40-like Beta Propeller Repeat 286 322 3.6E-14 T 29-03-2018 IPR011659 WD40-like Beta Propeller THSYN_RS19710 ea2b990a2de9f2bfb89eb2f2bddf8819 437 Pfam PF07676 WD40-like Beta Propeller Repeat 380 403 0.2 T 29-03-2018 IPR011659 WD40-like Beta Propeller THSYN_RS19710 ea2b990a2de9f2bfb89eb2f2bddf8819 437 Pfam PF07676 WD40-like Beta Propeller Repeat 247 278 4.5E-7 T 29-03-2018 IPR011659 WD40-like Beta Propeller THSYN_RS19710 ea2b990a2de9f2bfb89eb2f2bddf8819 437 Pfam PF07676 WD40-like Beta Propeller Repeat 209 232 3.1E-6 T 29-03-2018 IPR011659 WD40-like Beta Propeller THSYN_RS19710 ea2b990a2de9f2bfb89eb2f2bddf8819 437 Gene3D G3DSA:2.130.10.150 260 437 4.1E-34 T 29-03-2018 THSYN_RS19710 ea2b990a2de9f2bfb89eb2f2bddf8819 437 Gene3D G3DSA:3.40.50.10070 30 168 2.8E-31 T 29-03-2018 THSYN_RS19710 ea2b990a2de9f2bfb89eb2f2bddf8819 437 Hamap MF_00671 Protein TolB [tolB]. 9 432 33.844 T 29-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 THSYN_RS19710 ea2b990a2de9f2bfb89eb2f2bddf8819 437 Gene3D G3DSA:2.120.10.60 170 259 1.2E-11 T 29-03-2018 THSYN_RS19710 ea2b990a2de9f2bfb89eb2f2bddf8819 437 SUPERFAMILY SSF52964 36 166 4.58E-35 T 29-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 THSYN_RS13680 753db59668383c14b47c0352173cb3e4 690 Gene3D G3DSA:3.40.50.2300 118 265 6.1E-20 T 29-03-2018 THSYN_RS13680 753db59668383c14b47c0352173cb3e4 690 Gene3D G3DSA:3.30.70.270 276 430 9.3E-8 T 29-03-2018 THSYN_RS13680 753db59668383c14b47c0352173cb3e4 690 Gene3D G3DSA:3.20.20.450 444 686 2.5E-45 T 29-03-2018 IPR001633 EAL domain THSYN_RS13680 753db59668383c14b47c0352173cb3e4 690 SMART SM00448 140 253 1.2E-10 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS13680 753db59668383c14b47c0352173cb3e4 690 SUPERFAMILY SSF52172 137 264 3.7E-20 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS13680 753db59668383c14b47c0352173cb3e4 690 SUPERFAMILY SSF141868 448 678 8.5E-40 T 29-03-2018 IPR001633 EAL domain THSYN_RS13680 753db59668383c14b47c0352173cb3e4 690 Pfam PF00072 Response regulator receiver domain 142 253 5.1E-11 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS13680 753db59668383c14b47c0352173cb3e4 690 Pfam PF00563 EAL domain 449 674 3.1E-41 T 29-03-2018 IPR001633 EAL domain THSYN_RS13680 753db59668383c14b47c0352173cb3e4 690 SMART SM00052 441 681 1.3E-21 T 29-03-2018 IPR001633 EAL domain THSYN_RS13555 91ed9473cdd7cfd8259a094b76f448ad 148 Gene3D G3DSA:3.40.5.10 2 49 2.0E-18 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13555 91ed9473cdd7cfd8259a094b76f448ad 148 SUPERFAMILY SSF55653 57 146 6.02E-23 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal THSYN_RS13555 91ed9473cdd7cfd8259a094b76f448ad 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 24.127 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS13555 91ed9473cdd7cfd8259a094b76f448ad 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 2 47 2.5E-18 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13555 91ed9473cdd7cfd8259a094b76f448ad 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 2 146 6.8E-42 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS13555 91ed9473cdd7cfd8259a094b76f448ad 148 SUPERFAMILY SSF55658 1 57 6.98E-17 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal THSYN_RS13555 91ed9473cdd7cfd8259a094b76f448ad 148 Gene3D G3DSA:3.10.430.100 63 146 1.7E-24 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal THSYN_RS13555 91ed9473cdd7cfd8259a094b76f448ad 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13555 91ed9473cdd7cfd8259a094b76f448ad 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 145 9.9E-24 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 Pfam PF00512 His Kinase A (phospho-acceptor) domain 452 516 9.0E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 SMART SM00448 709 824 8.4E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 564 679 2.4E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 SMART SM00388 452 517 4.5E-24 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 Pfam PF08447 PAS fold 340 425 8.0E-20 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 312 439 7.3E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 SUPERFAMILY SSF52172 708 832 3.56E-37 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 SMART SM00086 390 432 1.5E-5 T 29-03-2018 IPR001610 PAC motif THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 Gene3D G3DSA:3.40.50.2300 702 837 4.4E-39 T 29-03-2018 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 SMART SM00073 863 960 1.3E-4 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 Pfam PF01627 Hpt domain 873 945 1.2E-9 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 SUPERFAMILY SSF55874 506 678 4.71E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 PRINTS PR00344 Bacterial sensor protein C-terminal signature 640 658 5.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 PRINTS PR00344 Bacterial sensor protein C-terminal signature 623 633 5.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 PRINTS PR00344 Bacterial sensor protein C-terminal signature 605 619 5.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 PRINTS PR00344 Bacterial sensor protein C-terminal signature 664 677 5.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 Pfam PF00072 Response regulator receiver domain 711 823 2.6E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 SUPERFAMILY SSF55785 324 435 1.92E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 SMART SM00387 564 680 1.6E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 Gene3D G3DSA:3.30.450.20 283 451 6.7E-36 T 29-03-2018 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 SUPERFAMILY SSF47226 852 950 2.62E-20 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 SUPERFAMILY SSF47226 807 820 2.62E-20 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 Gene3D G3DSA:3.30.565.10 521 688 7.0E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 SUPERFAMILY SSF47384 437 518 1.29E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 Gene3D G3DSA:1.20.120.160 848 960 5.9E-17 T 29-03-2018 THSYN_RS10090 b940fce73baf19cc7e2f0284840cea2b 1048 Gene3D G3DSA:1.10.287.130 452 513 8.9E-21 T 29-03-2018 THSYN_RS29725 23ca3bf730bc401faf6b13e6d03381e0 84 Gene3D G3DSA:2.40.50.220 1 83 1.0E-19 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml THSYN_RS29725 23ca3bf730bc401faf6b13e6d03381e0 84 SUPERFAMILY SSF159133 1 81 8.89E-23 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml THSYN_RS29725 23ca3bf730bc401faf6b13e6d03381e0 84 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 76 8.9E-20 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml THSYN_RS29725 23ca3bf730bc401faf6b13e6d03381e0 84 TIGRFAM TIGR02703 carboxysome_A: carboxysome peptide A 1 78 4.4E-45 T 29-03-2018 IPR014076 Carboxysome peptide A THSYN_RS29725 23ca3bf730bc401faf6b13e6d03381e0 84 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 10 78 4.0E-29 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml THSYN_RS06535 36ddf395909e9fb349d4bcd41e6e1226 324 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 50 323 61.742 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 THSYN_RS06535 36ddf395909e9fb349d4bcd41e6e1226 324 Gene3D G3DSA:1.20.120.140 220 324 8.8E-25 T 29-03-2018 THSYN_RS06535 36ddf395909e9fb349d4bcd41e6e1226 324 SUPERFAMILY SSF52540 119 323 1.31E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06535 36ddf395909e9fb349d4bcd41e6e1226 324 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 296 309 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THSYN_RS06535 36ddf395909e9fb349d4bcd41e6e1226 324 SMART SM00962 122 323 5.9E-120 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THSYN_RS06535 36ddf395909e9fb349d4bcd41e6e1226 324 Pfam PF00448 SRP54-type protein, GTPase domain 122 323 1.3E-78 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THSYN_RS06535 36ddf395909e9fb349d4bcd41e6e1226 324 SUPERFAMILY SSF47364 21 101 5.76E-21 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THSYN_RS06535 36ddf395909e9fb349d4bcd41e6e1226 324 SMART SM00963 26 107 2.3E-26 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THSYN_RS06535 36ddf395909e9fb349d4bcd41e6e1226 324 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 50 322 2.3E-110 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 THSYN_RS06535 36ddf395909e9fb349d4bcd41e6e1226 324 Gene3D G3DSA:3.40.50.300 100 217 3.5E-17 T 29-03-2018 THSYN_RS06535 36ddf395909e9fb349d4bcd41e6e1226 324 SMART SM00382 121 312 2.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS06535 36ddf395909e9fb349d4bcd41e6e1226 324 Pfam PF02881 SRP54-type protein, helical bundle domain 37 103 4.6E-13 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THSYN_RS06535 36ddf395909e9fb349d4bcd41e6e1226 324 Gene3D G3DSA:1.20.120.140 14 99 1.7E-22 T 29-03-2018 THSYN_RS10665 43ce841e40595bf81818c03e85c3524f 114 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 4 111 2.3E-27 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR THSYN_RS10665 43ce841e40595bf81818c03e85c3524f 114 SUPERFAMILY SSF52833 1 113 1.39E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS10665 43ce841e40595bf81818c03e85c3524f 114 Pfam PF03960 ArsC family 8 111 1.1E-13 T 29-03-2018 IPR006660 Arsenate reductase-like THSYN_RS10665 43ce841e40595bf81818c03e85c3524f 114 Gene3D G3DSA:3.40.30.10 1 114 5.7E-35 T 29-03-2018 THSYN_RS07760 ee130b8f1397b5be15056aed0809d68a 141 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 5 138 2.1E-41 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 THSYN_RS07760 ee130b8f1397b5be15056aed0809d68a 141 Pfam PF01894 Uncharacterised protein family UPF0047 18 134 2.9E-38 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 THSYN_RS07760 ee130b8f1397b5be15056aed0809d68a 141 SUPERFAMILY SSF111038 2 138 9.68E-47 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 THSYN_RS07760 ee130b8f1397b5be15056aed0809d68a 141 PIRSF PIRSF004681 1 138 3.8E-49 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 THSYN_RS07760 ee130b8f1397b5be15056aed0809d68a 141 Gene3D G3DSA:2.60.120.460 1 138 1.1E-52 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 THSYN_RS30855 b76b2f83c4dcd6a0ce52a1c35c6df5ec 79 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 2 78 1.9E-29 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS30855 b76b2f83c4dcd6a0ce52a1c35c6df5ec 79 Gene3D G3DSA:1.10.1220.10 4 44 1.3E-10 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS30855 b76b2f83c4dcd6a0ce52a1c35c6df5ec 79 SUPERFAMILY SSF47598 3 43 6.45E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS30855 b76b2f83c4dcd6a0ce52a1c35c6df5ec 79 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 3 68 1.5E-26 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS01655 88f4ae6873a4bc5aee22a87d5282ce24 131 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 123 10.889 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS01655 88f4ae6873a4bc5aee22a87d5282ce24 131 SUPERFAMILY SSF88723 1 121 8.41E-22 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS01655 88f4ae6873a4bc5aee22a87d5282ce24 131 Pfam PF01850 PIN domain 3 116 1.3E-16 T 29-03-2018 IPR002716 PIN domain THSYN_RS01655 88f4ae6873a4bc5aee22a87d5282ce24 131 Gene3D G3DSA:3.40.50.1010 2 123 5.4E-22 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS19475 e21d63ad5284b49d2ccf0056d5419224 751 Pfam PF00069 Protein kinase domain 95 226 2.3E-7 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS19475 e21d63ad5284b49d2ccf0056d5419224 751 Pfam PF03781 Sulfatase-modifying factor enzyme 1 526 749 6.7E-51 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS19475 e21d63ad5284b49d2ccf0056d5419224 751 Gene3D G3DSA:3.90.1580.10 521 567 2.9E-12 T 29-03-2018 THSYN_RS19475 e21d63ad5284b49d2ccf0056d5419224 751 Gene3D G3DSA:3.90.1580.10 568 746 1.1E-52 T 29-03-2018 THSYN_RS19475 e21d63ad5284b49d2ccf0056d5419224 751 SMART SM00220 12 306 0.0085 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS19475 e21d63ad5284b49d2ccf0056d5419224 751 Gene3D G3DSA:1.10.510.10 91 505 3.7E-18 T 29-03-2018 THSYN_RS19475 e21d63ad5284b49d2ccf0056d5419224 751 SUPERFAMILY SSF56112 67 300 6.6E-19 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS19475 e21d63ad5284b49d2ccf0056d5419224 751 SUPERFAMILY SSF56436 526 751 3.06E-69 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 73 419 7.2E-21 T 29-03-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 SUPERFAMILY SSF101908 430 664 2.75E-6 T 29-03-2018 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 Pfam PF14312 FG-GAP repeat 688 733 3.7E-9 T 29-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 Pfam PF14312 FG-GAP repeat 473 511 3.2E-9 T 29-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 Pfam PF14312 FG-GAP repeat 577 626 1.1E-12 T 29-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 Gene3D G3DSA:2.70.98.10 33 417 1.2E-34 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 SMART SM00191 590 640 0.12 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 SMART SM00191 701 747 41.0 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 SMART SM00191 431 479 130.0 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 SMART SM00191 483 525 0.22 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 SMART SM00191 752 802 190.0 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 SMART SM00191 529 584 100.0 T 29-03-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 SUPERFAMILY SSF74650 73 417 5.02E-17 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 Gene3D G3DSA:2.130.10.130 552 655 2.0E-11 T 29-03-2018 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 Gene3D G3DSA:2.130.10.130 432 537 2.7E-7 T 29-03-2018 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 Gene3D G3DSA:2.130.10.130 656 799 0.001 T 29-03-2018 THSYN_RS02845 858c932caa80bff30edaa35bd910208b 803 Gene3D G3DSA:2.40.50.100 538 551 0.14 T 29-03-2018 THSYN_RS14930 5cdbfa97893b95d289513cc74ff6f47e 108 SUPERFAMILY SSF143100 1 75 1.31E-14 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS14930 5cdbfa97893b95d289513cc74ff6f47e 108 Pfam PF05534 HicB family 54 104 7.7E-21 T 29-03-2018 IPR008651 Uncharacterised protein family HicB THSYN_RS14930 5cdbfa97893b95d289513cc74ff6f47e 108 Gene3D G3DSA:3.30.2390.10 7 63 2.5E-7 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS14930 5cdbfa97893b95d289513cc74ff6f47e 108 SUPERFAMILY SSF47598 69 107 3.45E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS14930 5cdbfa97893b95d289513cc74ff6f47e 108 Gene3D G3DSA:1.10.1220.10 64 107 1.2E-14 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 Gene3D G3DSA:3.40.50.300 71 296 6.1E-9 T 29-03-2018 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 Gene3D G3DSA:1.10.10.10 297 623 1.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 SUPERFAMILY SSF52540 70 328 8.81E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 Gene3D G3DSA:1.25.40.10 693 747 1.0E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 SUPERFAMILY SSF46785 364 430 2.27E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 SUPERFAMILY SSF48452 688 860 5.5E-30 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 Pfam PF13414 TPR repeat 739 772 4.4E-7 T 29-03-2018 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 Pfam PF13414 TPR repeat 774 807 5.9E-8 T 29-03-2018 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 Gene3D G3DSA:1.25.40.10 854 995 0.0083 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 Gene3D G3DSA:1.20.120.420 796 853 3.7E-16 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 SMART SM00028 795 829 0.73 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 SMART SM00028 691 724 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 SMART SM00028 725 759 0.12 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 SMART SM00028 832 864 48.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 SMART SM00028 760 794 1.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 SMART SM00382 97 277 1.8E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 Pfam PF13432 Tetratricopeptide repeat 810 865 0.003 T 29-03-2018 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 Pfam PF13191 AAA ATPase domain 74 242 8.2E-11 T 29-03-2018 THSYN_RS00555 a624cd4bbb509c27ea87d2f5e42ec91c 1043 Gene3D G3DSA:1.25.40.10 748 795 6.4E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01595 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS07460 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS04675 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS01855 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS17560 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS25435 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS03075 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS28960 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS20195 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS18645 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS17875 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS17170 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS06690 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS27100 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS02040 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS20205 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS31175 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS00495 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS26640 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS21330 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS06105 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS26240 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS17685 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS04925 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS28925 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS00785 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS03720 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS28045 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS12600 547607efa533632c491a626978adcd41 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS32800 38055932849f8de8ab74c72d75c2b17f 1017 SUPERFAMILY SSF53335 212 295 8.35E-10 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS32800 38055932849f8de8ab74c72d75c2b17f 1017 Pfam PF06634 Protein of unknown function (DUF1156) 34 96 1.3E-17 T 29-03-2018 IPR009537 Domain of unknown function DUF1156 THSYN_RS32800 38055932849f8de8ab74c72d75c2b17f 1017 SUPERFAMILY SSF53335 628 643 5.49E-5 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS32800 38055932849f8de8ab74c72d75c2b17f 1017 SUPERFAMILY SSF53335 678 760 5.49E-5 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS32800 38055932849f8de8ab74c72d75c2b17f 1017 Gene3D G3DSA:3.40.50.150 197 752 3.9E-30 T 29-03-2018 THSYN_RS06725 d3b17fd5bce37ce3884902101a96eaa7 188 Pfam PF06853 Protein of unknown function (DUF1249) 38 167 7.8E-26 T 29-03-2018 IPR009659 Protein of unknown function DUF1249 THSYN_RS22560 bd69bec34f5822b97e44bad6f21577d4 160 Gene3D G3DSA:2.40.50.140 26 124 1.7E-34 T 29-03-2018 THSYN_RS22560 bd69bec34f5822b97e44bad6f21577d4 160 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 140 32.311 T 29-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 THSYN_RS22560 bd69bec34f5822b97e44bad6f21577d4 160 Pfam PF03100 CcmE 4 130 2.1E-46 T 29-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 THSYN_RS22560 bd69bec34f5822b97e44bad6f21577d4 160 SUPERFAMILY SSF82093 29 136 2.75E-39 T 29-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 743 789 0.034 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 661 742 1.1E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 23 114 3.1E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 156 204 2.7E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 403 458 0.064 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SUPERFAMILY SSF48452 462 611 8.35E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SUPERFAMILY SSF48452 135 299 4.55E-27 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Pfam PF13432 Tetratricopeptide repeat 523 586 1.9E-9 T 29-03-2018 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Pfam PF13432 Tetratricopeptide repeat 695 753 2.4E-4 T 29-03-2018 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Pfam PF13432 Tetratricopeptide repeat 244 296 2.0E-4 T 29-03-2018 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Pfam PF13432 Tetratricopeptide repeat 463 512 0.0022 T 29-03-2018 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Pfam PF13432 Tetratricopeptide repeat 797 855 3.0E-5 T 29-03-2018 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SUPERFAMILY SSF48452 22 183 3.8E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 313 366 1.0E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 367 402 1.2E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 230 310 8.3E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Pfam PF14559 Tetratricopeptide repeat 331 390 5.9E-6 T 29-03-2018 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SUPERFAMILY SSF48452 315 518 4.1E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 876 944 5.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 205 229 4.6E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 115 155 0.049 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 459 550 2.4E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SUPERFAMILY SSF48452 618 854 2.85E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SUPERFAMILY SSF48452 843 926 1.37E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 519 552 22.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 792 825 16.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 725 758 1.2 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 315 348 410.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 349 382 20.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 239 272 450.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 691 724 330.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 35 68 0.72 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 171 204 12.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 826 858 83.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 383 416 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 205 238 3.8 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 137 170 1.3 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 553 586 4.2 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 SMART SM00028 657 690 130.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 790 875 4.6E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 601 660 6.3E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 Gene3D G3DSA:1.25.40.10 551 600 3.0E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24555 45e0194034217ebea22d214e84960de9 958 TIGRFAM TIGR02917 PEP_TPR_lipo: putative PEP-CTERM system TPR-repeat lipoprotein 21 916 1.4E-180 T 29-03-2018 IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 Gene3D G3DSA:3.30.565.10 201 358 1.8E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 SUPERFAMILY SSF55785 11 107 8.72E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 SUPERFAMILY SSF55874 204 353 3.27E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 241 354 8.3E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 Pfam PF00512 His Kinase A (phospho-acceptor) domain 139 193 5.2E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 Pfam PF00989 PAS fold 12 116 5.5E-8 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 SUPERFAMILY SSF47384 128 197 4.51E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 13 111 4.3E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 SMART SM00387 240 355 1.1E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 SMART SM00388 136 201 1.3E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 Gene3D G3DSA:3.30.450.20 9 115 5.2E-16 T 29-03-2018 THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 Gene3D G3DSA:1.10.287.130 116 195 8.9E-13 T 29-03-2018 THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 352 1.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 301 1.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00055 2e3d3467b821bfb885d17db32d27eaf4 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 334 1.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01025 6f5bd3e40180c3def3fb107b5c09f088 381 Gene3D G3DSA:1.20.120.330 128 230 7.3E-4 T 29-03-2018 THSYN_RS01025 6f5bd3e40180c3def3fb107b5c09f088 381 Gene3D G3DSA:3.90.20.10 11 112 0.0061 T 29-03-2018 THSYN_RS12875 d6ea80eb9ef1ef67626bbad84d80286e 232 SUPERFAMILY SSF47781 153 212 4.45E-14 T 29-03-2018 IPR010994 RuvA domain 2-like THSYN_RS12875 d6ea80eb9ef1ef67626bbad84d80286e 232 Gene3D G3DSA:1.10.150.20 159 219 9.7E-16 T 29-03-2018 THSYN_RS12875 d6ea80eb9ef1ef67626bbad84d80286e 232 Gene3D G3DSA:3.40.50.10130 7 141 1.0E-24 T 29-03-2018 THSYN_RS12875 d6ea80eb9ef1ef67626bbad84d80286e 232 SMART SM00891 8 89 8.9E-17 T 29-03-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 THSYN_RS12875 d6ea80eb9ef1ef67626bbad84d80286e 232 SMART SM00278 193 212 1.3 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THSYN_RS12875 d6ea80eb9ef1ef67626bbad84d80286e 232 SMART SM00278 161 180 2.5 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THSYN_RS12875 d6ea80eb9ef1ef67626bbad84d80286e 232 SUPERFAMILY SSF52980 8 134 3.22E-25 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS12875 d6ea80eb9ef1ef67626bbad84d80286e 232 Pfam PF14520 Helix-hairpin-helix domain 161 210 1.9E-13 T 29-03-2018 THSYN_RS12875 d6ea80eb9ef1ef67626bbad84d80286e 232 Pfam PF02732 ERCC4 domain 11 130 1.7E-14 T 29-03-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 THSYN_RS26625 b6b6d579b20ce68a166a56ad4d258402 324 SUPERFAMILY SSF56042 146 319 1.14E-36 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS26625 b6b6d579b20ce68a166a56ad4d258402 324 Gene3D G3DSA:3.30.1330.10 1 146 5.2E-32 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS26625 b6b6d579b20ce68a166a56ad4d258402 324 Gene3D G3DSA:3.90.650.10 147 320 5.3E-42 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS26625 b6b6d579b20ce68a166a56ad4d258402 324 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 316 28.65 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 THSYN_RS26625 b6b6d579b20ce68a166a56ad4d258402 324 Pfam PF00586 AIR synthase related protein, N-terminal domain 27 140 5.0E-21 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS26625 b6b6d579b20ce68a166a56ad4d258402 324 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 3 319 3.5E-92 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 THSYN_RS26625 b6b6d579b20ce68a166a56ad4d258402 324 SUPERFAMILY SSF55326 2 140 4.36E-31 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS26625 b6b6d579b20ce68a166a56ad4d258402 324 PIRSF PIRSF005303 1 319 8.3E-77 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 THSYN_RS26625 b6b6d579b20ce68a166a56ad4d258402 324 Pfam PF02769 AIR synthase related protein, C-terminal domain 152 298 1.1E-9 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS19270 3a27dd13896bf516782278e27b9d62b1 306 SUPERFAMILY SSF54862 41 123 6.98E-18 T 29-03-2018 THSYN_RS19270 3a27dd13896bf516782278e27b9d62b1 306 Pfam PF00037 4Fe-4S binding domain 68 89 3.2E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS19270 3a27dd13896bf516782278e27b9d62b1 306 SUPERFAMILY SSF52540 1 54 2.58E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19270 3a27dd13896bf516782278e27b9d62b1 306 SUPERFAMILY SSF52540 121 294 2.58E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19270 3a27dd13896bf516782278e27b9d62b1 306 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 103 114 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS19270 3a27dd13896bf516782278e27b9d62b1 306 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 269 1.4E-13 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THSYN_RS19270 3a27dd13896bf516782278e27b9d62b1 306 Gene3D G3DSA:3.40.50.300 1 305 1.1E-41 T 29-03-2018 THSYN_RS18495 2ecc7fe0be8e9880c5b42ecb63e0113d 352 Pfam PF01734 Patatin-like phospholipase 24 217 1.5E-17 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 THSYN_RS18495 2ecc7fe0be8e9880c5b42ecb63e0113d 352 SUPERFAMILY SSF52151 23 97 4.19E-49 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS18495 2ecc7fe0be8e9880c5b42ecb63e0113d 352 SUPERFAMILY SSF52151 128 331 4.19E-49 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS18495 2ecc7fe0be8e9880c5b42ecb63e0113d 352 Gene3D G3DSA:3.40.1090.10 11 249 1.3E-37 T 29-03-2018 THSYN_RS10180 b06590593c4eaf9fd8f15d31d9024c90 143 Gene3D G3DSA:3.30.420.140 1 142 2.0E-36 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 THSYN_RS10180 b06590593c4eaf9fd8f15d31d9024c90 143 Pfam PF03652 Holliday junction resolvase 4 137 2.1E-36 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 THSYN_RS10180 b06590593c4eaf9fd8f15d31d9024c90 143 SMART SM00732 2 102 1.4E-23 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 THSYN_RS10180 b06590593c4eaf9fd8f15d31d9024c90 143 SUPERFAMILY SSF53098 2 138 3.79E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS10180 b06590593c4eaf9fd8f15d31d9024c90 143 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 2 140 23.088 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 THSYN_RS10180 b06590593c4eaf9fd8f15d31d9024c90 143 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 5 136 7.5E-36 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 THSYN_RS14735 566306a58d5867f6ac841d77e05b5730 133 Gene3D G3DSA:1.20.1440.60 10 116 9.1E-9 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS14735 566306a58d5867f6ac841d77e05b5730 133 SUPERFAMILY SSF158446 12 112 2.22E-5 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS28920 d30cef8f848a144c38b9da59435aed65 314 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 123 6.6E-19 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THSYN_RS28920 d30cef8f848a144c38b9da59435aed65 314 SUPERFAMILY SSF51735 132 273 4.95E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS28920 d30cef8f848a144c38b9da59435aed65 314 SUPERFAMILY SSF50129 9 164 1.57E-39 T 29-03-2018 IPR011032 GroES-like THSYN_RS28920 d30cef8f848a144c38b9da59435aed65 314 Gene3D G3DSA:3.40.50.720 153 265 1.2E-18 T 29-03-2018 THSYN_RS28920 d30cef8f848a144c38b9da59435aed65 314 Gene3D G3DSA:3.90.180.10 2 152 2.6E-32 T 29-03-2018 THSYN_RS28920 d30cef8f848a144c38b9da59435aed65 314 Pfam PF00107 Zinc-binding dehydrogenase 166 269 2.8E-7 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THSYN_RS03520 01d1843332c49890171f8923e72676a0 310 Pfam PF01795 MraW methylase family 5 308 1.8E-107 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS03520 01d1843332c49890171f8923e72676a0 310 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 4 308 8.8E-107 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS03520 01d1843332c49890171f8923e72676a0 310 PIRSF PIRSF004486 2 310 3.9E-98 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS03520 01d1843332c49890171f8923e72676a0 310 SUPERFAMILY SSF81799 115 214 1.14E-32 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS03520 01d1843332c49890171f8923e72676a0 310 Gene3D G3DSA:3.40.50.150 6 121 1.0E-16 T 29-03-2018 THSYN_RS03520 01d1843332c49890171f8923e72676a0 310 Gene3D G3DSA:1.10.150.170 122 216 2.2E-34 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS03520 01d1843332c49890171f8923e72676a0 310 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 6 309 37.726 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS03520 01d1843332c49890171f8923e72676a0 310 SUPERFAMILY SSF53335 214 309 3.71E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS03520 01d1843332c49890171f8923e72676a0 310 SUPERFAMILY SSF53335 5 114 3.71E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS24690 879de241183c095e29ed94998ec7e97f 390 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 4 166 1.4E-60 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THSYN_RS24690 879de241183c095e29ed94998ec7e97f 390 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 2 18 3.2E-14 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THSYN_RS24690 879de241183c095e29ed94998ec7e97f 390 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 148 161 3.2E-14 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THSYN_RS24690 879de241183c095e29ed94998ec7e97f 390 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 102 116 3.2E-14 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THSYN_RS24690 879de241183c095e29ed94998ec7e97f 390 Gene3D G3DSA:3.90.120.10 235 353 1.8E-13 T 29-03-2018 THSYN_RS24690 879de241183c095e29ed94998ec7e97f 390 Gene3D G3DSA:3.40.50.150 1 174 1.4E-57 T 29-03-2018 THSYN_RS24690 879de241183c095e29ed94998ec7e97f 390 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 63 75 - T 29-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 THSYN_RS24690 879de241183c095e29ed94998ec7e97f 390 SUPERFAMILY SSF53335 206 365 9.26E-78 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS24690 879de241183c095e29ed94998ec7e97f 390 SUPERFAMILY SSF53335 2 164 9.26E-78 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS24690 879de241183c095e29ed94998ec7e97f 390 Pfam PF00145 C-5 cytosine-specific DNA methylase 2 167 9.7E-60 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS24690 879de241183c095e29ed94998ec7e97f 390 Pfam PF00145 C-5 cytosine-specific DNA methylase 304 365 1.1E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 Gene3D G3DSA:3.30.70.1430 39 141 1.1E-23 T 29-03-2018 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 SUPERFAMILY SSF82693 137 183 1.62E-24 T 29-03-2018 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 SUPERFAMILY SSF82693 276 332 1.62E-24 T 29-03-2018 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 SUPERFAMILY SSF82693 563 669 2.3E-26 T 29-03-2018 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 Gene3D G3DSA:3.30.2090.10 182 277 3.8E-19 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 Pfam PF00873 AcrB/AcrD/AcrF family 2 1025 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 Gene3D G3DSA:3.30.70.1430 565 669 2.8E-19 T 29-03-2018 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 Gene3D G3DSA:3.30.70.1440 670 764 1.7E-19 T 29-03-2018 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 SUPERFAMILY SSF82866 298 499 4.58E-50 T 29-03-2018 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 Gene3D G3DSA:3.30.70.1320 765 842 9.1E-5 T 29-03-2018 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 SUPERFAMILY SSF82866 804 1028 8.37E-44 T 29-03-2018 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 SUPERFAMILY SSF82714 720 803 6.15E-19 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 3.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 3.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 3.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 3.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 3.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 3.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 3.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 3.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 PRINTS PR00702 Acriflavin resistance protein family signature 550 567 3.1E-89 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 SUPERFAMILY SSF82714 184 273 9.81E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1030 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 Gene3D G3DSA:1.20.1640.10 288 508 1.8E-48 T 29-03-2018 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 Gene3D G3DSA:1.20.1640.10 843 1034 7.2E-34 T 29-03-2018 THSYN_RS14230 c4786604cbc3455ef9a620650dbf40bb 1054 SUPERFAMILY SSF82693 39 132 5.76E-25 T 29-03-2018 THSYN_RS12360 154171566b5f2954c86225002cb644a2 439 Gene3D G3DSA:1.20.58.340 235 355 9.0E-7 T 29-03-2018 THSYN_RS12360 154171566b5f2954c86225002cb644a2 439 Gene3D G3DSA:1.20.58.340 356 427 1.1E-8 T 29-03-2018 THSYN_RS12360 154171566b5f2954c86225002cb644a2 439 Gene3D G3DSA:3.30.460.20 114 234 1.5E-9 T 29-03-2018 THSYN_RS12360 154171566b5f2954c86225002cb644a2 439 SUPERFAMILY SSF144083 359 421 1.83E-8 T 29-03-2018 THSYN_RS12360 154171566b5f2954c86225002cb644a2 439 SUPERFAMILY SSF143865 105 362 1.15E-29 T 29-03-2018 THSYN_RS12360 154171566b5f2954c86225002cb644a2 439 Pfam PF01544 CorA-like Mg2+ transporter protein 133 412 9.9E-33 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 THSYN_RS12360 154171566b5f2954c86225002cb644a2 439 SUPERFAMILY SSF158791 33 100 2.88E-9 T 29-03-2018 THSYN_RS12360 154171566b5f2954c86225002cb644a2 439 Gene3D G3DSA:1.10.220.30 44 113 7.5E-5 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical THSYN_RS19740 491955a0ae6ff62b5854c04c6c60f63e 278 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 27 94 2.0E-17 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 THSYN_RS19740 491955a0ae6ff62b5854c04c6c60f63e 278 SUPERFAMILY SSF53223 10 106 2.24E-26 T 29-03-2018 THSYN_RS19740 491955a0ae6ff62b5854c04c6c60f63e 278 Gene3D G3DSA:3.40.50.10860 22 117 7.0E-31 T 29-03-2018 THSYN_RS19740 491955a0ae6ff62b5854c04c6c60f63e 278 Gene3D G3DSA:3.40.50.720 118 273 3.2E-26 T 29-03-2018 THSYN_RS19740 491955a0ae6ff62b5854c04c6c60f63e 278 SUPERFAMILY SSF51735 107 267 1.58E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS04775 1eda716bebba641d054444610053905a 1039 SMART SM00487 257 457 4.4E-14 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS04775 1eda716bebba641d054444610053905a 1039 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 78 694 6.5E-135 T 29-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 THSYN_RS04775 1eda716bebba641d054444610053905a 1039 SUPERFAMILY SSF52540 232 458 1.64E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04775 1eda716bebba641d054444610053905a 1039 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 28 204 1.3E-27 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THSYN_RS04775 1eda716bebba641d054444610053905a 1039 SUPERFAMILY SSF52540 504 548 7.59E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04775 1eda716bebba641d054444610053905a 1039 SUPERFAMILY SSF52540 447 453 7.59E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04775 1eda716bebba641d054444610053905a 1039 SUPERFAMILY SSF52540 386 420 7.59E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04775 1eda716bebba641d054444610053905a 1039 SUPERFAMILY SSF52540 592 676 7.59E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04775 1eda716bebba641d054444610053905a 1039 Gene3D G3DSA:3.40.50.300 234 444 1.2E-21 T 29-03-2018 THSYN_RS04775 1eda716bebba641d054444610053905a 1039 Pfam PF04851 Type III restriction enzyme, res subunit 259 420 1.4E-13 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS03255 f9baebf6f2a137157f2b3c8b93c871e7 335 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 37 76 2.7E-8 T 29-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THSYN_RS03255 f9baebf6f2a137157f2b3c8b93c871e7 335 PIRSF PIRSF005963 5 333 1.3E-124 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THSYN_RS03255 f9baebf6f2a137157f2b3c8b93c871e7 335 Gene3D G3DSA:3.20.20.70 41 326 1.3E-23 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS03255 f9baebf6f2a137157f2b3c8b93c871e7 335 SUPERFAMILY SSF102114 53 320 5.49E-59 T 29-03-2018 THSYN_RS03255 f9baebf6f2a137157f2b3c8b93c871e7 335 Pfam PF04055 Radical SAM superfamily 94 253 2.0E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS03255 f9baebf6f2a137157f2b3c8b93c871e7 335 Hamap MF_00206 Lipoyl synthase [lipA]. 1 327 146.212 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THSYN_RS03255 f9baebf6f2a137157f2b3c8b93c871e7 335 TIGRFAM TIGR00510 lipA: lipoyl synthase 36 318 9.0E-121 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THSYN_RS03255 f9baebf6f2a137157f2b3c8b93c871e7 335 SMART SM00729 87 296 1.3E-4 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS11630 ce2e3c7eb19479682d3af579e2d6a38c 159 SUPERFAMILY SSF55961 7 152 8.8E-10 T 29-03-2018 THSYN_RS11630 ce2e3c7eb19479682d3af579e2d6a38c 159 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 7 147 3.0E-8 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase THSYN_RS11630 ce2e3c7eb19479682d3af579e2d6a38c 159 Gene3D G3DSA:3.30.530.20 3 156 1.5E-11 T 29-03-2018 IPR023393 START-like domain THSYN_RS24780 c8d59cf18dad085bdcc096123b258cc6 87 Hamap MF_00460 Protein RnfH [rnfH]. 1 87 22.133 T 29-03-2018 IPR005346 RnfH protein THSYN_RS24780 c8d59cf18dad085bdcc096123b258cc6 87 Pfam PF03658 RnfH family Ubiquitin 1 83 7.7E-33 T 29-03-2018 IPR005346 RnfH protein THSYN_RS24780 c8d59cf18dad085bdcc096123b258cc6 87 Gene3D G3DSA:3.10.20.280 1 84 9.2E-30 T 29-03-2018 IPR005346 RnfH protein THSYN_RS24780 c8d59cf18dad085bdcc096123b258cc6 87 SUPERFAMILY SSF54285 1 75 4.8E-24 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THSYN_RS00525 25d798232ae890aa4112310c165a4957 96 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 55 1.8E-14 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS00525 25d798232ae890aa4112310c165a4957 96 Gene3D G3DSA:3.40.1620.10 1 48 1.2E-15 T 29-03-2018 THSYN_RS00525 25d798232ae890aa4112310c165a4957 96 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 47 8.1E-11 T 29-03-2018 THSYN_RS00525 25d798232ae890aa4112310c165a4957 96 SUPERFAMILY SSF143120 1 73 5.89E-13 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS10410 3f14f3c443404038619fa3fc34c98f94 357 SUPERFAMILY SSF53067 58 178 4.53E-13 T 29-03-2018 THSYN_RS10410 3f14f3c443404038619fa3fc34c98f94 357 Pfam PF11104 Type IV pilus assembly protein PilM; 13 356 2.4E-129 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM THSYN_RS10410 3f14f3c443404038619fa3fc34c98f94 357 Gene3D G3DSA:3.30.420.40 194 323 4.3E-15 T 29-03-2018 THSYN_RS10410 3f14f3c443404038619fa3fc34c98f94 357 PIRSF PIRSF019169 1 357 8.1E-119 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM THSYN_RS10410 3f14f3c443404038619fa3fc34c98f94 357 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 9 356 5.5E-112 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM THSYN_RS10410 3f14f3c443404038619fa3fc34c98f94 357 SMART SM00842 11 182 0.002 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 THSYN_RS10410 3f14f3c443404038619fa3fc34c98f94 357 SUPERFAMILY SSF53067 194 355 3.2E-23 T 29-03-2018 THSYN_RS10410 3f14f3c443404038619fa3fc34c98f94 357 Gene3D G3DSA:3.30.420.40 1 175 1.6E-32 T 29-03-2018 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 884 948 6.8E-17 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 Gene3D G3DSA:1.10.287.380 877 947 6.7E-23 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 SUPERFAMILY SSF50677 197 363 3.14E-51 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 SUPERFAMILY SSF47323 636 898 2.24E-71 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 931 0.0 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 625 7.7E-196 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 SUPERFAMILY SSF46589 884 948 1.36E-14 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 1.7E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 PRINTS PR00986 Valyl-tRNA synthetase signature 500 518 1.7E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 1.7E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 PRINTS PR00986 Valyl-tRNA synthetase signature 469 490 1.7E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 PRINTS PR00986 Valyl-tRNA synthetase signature 369 382 1.7E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 SUPERFAMILY SSF52374 365 564 1.71E-132 T 29-03-2018 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 SUPERFAMILY SSF52374 602 635 1.71E-132 T 29-03-2018 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 SUPERFAMILY SSF52374 3 195 1.71E-132 T 29-03-2018 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 Gene3D G3DSA:3.40.50.620 32 536 5.4E-115 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 Gene3D G3DSA:1.10.730.10 537 843 4.2E-70 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 Pfam PF08264 Anticodon-binding domain of tRNA 668 826 3.5E-43 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 THSYN_RS16435 65314110ee7f23e679cb4905de4da7d3 951 Hamap MF_02004 Valine--tRNA ligase [valS]. 2 949 15.799 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THSYN_RS12230 235369c2f81b58813b5f23262cadff54 113 Pfam PF11848 Domain of unknown function (DUF3368) 67 111 8.4E-8 T 29-03-2018 IPR021799 Protein of unknown function DUF3368 THSYN_RS12230 235369c2f81b58813b5f23262cadff54 113 Gene3D G3DSA:3.40.50.1010 29 70 0.003 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 SUPERFAMILY SSF53738 154 254 1.84E-28 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 256 364 7.7E-29 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 2.7E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 2.7E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 2.7E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 371 439 1.6E-13 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 133 1.5E-44 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 Gene3D G3DSA:3.30.310.50 372 444 7.3E-19 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 440 1.3E-186 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 SUPERFAMILY SSF55957 356 443 1.11E-22 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 Gene3D G3DSA:3.40.120.10 1 152 1.7E-48 T 29-03-2018 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 155 252 1.4E-17 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 SUPERFAMILY SSF53738 256 363 4.71E-29 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 Gene3D G3DSA:3.40.120.10 154 264 2.6E-30 T 29-03-2018 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 Gene3D G3DSA:3.40.120.10 265 371 2.2E-28 T 29-03-2018 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 442 46.189 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS26130 d1d5152ec2b638e35f565bfd2a9495ca 448 SUPERFAMILY SSF53738 2 179 7.85E-48 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS28635 12b2e0686c18982a86f59d665b5c38c5 87 SMART SM00530 10 85 0.0012 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS28635 12b2e0686c18982a86f59d665b5c38c5 87 Gene3D G3DSA:1.10.10.60 5 46 5.6E-7 T 29-03-2018 THSYN_RS28635 12b2e0686c18982a86f59d665b5c38c5 87 Gene3D G3DSA:3.30.1190.10 47 79 1.9E-6 T 29-03-2018 THSYN_RS28635 12b2e0686c18982a86f59d665b5c38c5 87 Pfam PF15731 Antitoxin component of bacterial toxin-antitoxin system, MqsA 4 85 8.1E-10 T 29-03-2018 IPR032758 Antitoxin MqsA/HigA-2 THSYN_RS28635 12b2e0686c18982a86f59d665b5c38c5 87 SUPERFAMILY SSF47413 32 70 3.58E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS09675 fcd16a3eebe0670fb80634e172be5d94 196 Gene3D G3DSA:3.90.950.10 1 192 4.2E-55 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THSYN_RS09675 fcd16a3eebe0670fb80634e172be5d94 196 PIRSF PIRSF006305 1 194 1.7E-43 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 THSYN_RS09675 fcd16a3eebe0670fb80634e172be5d94 196 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 185 3.5E-49 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 THSYN_RS09675 fcd16a3eebe0670fb80634e172be5d94 196 Pfam PF02545 Maf-like protein 5 186 3.2E-44 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 THSYN_RS09675 fcd16a3eebe0670fb80634e172be5d94 196 Hamap MF_00528 Septum formation protein Maf [maf]. 4 192 29.709 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 THSYN_RS09675 fcd16a3eebe0670fb80634e172be5d94 196 SUPERFAMILY SSF52972 2 186 3.86E-57 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THSYN_RS02535 c4402b209ff7907d1e43639714d3a679 300 Pfam PF04381 Putative exonuclease, RdgC 2 294 3.8E-106 T 29-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 THSYN_RS02535 c4402b209ff7907d1e43639714d3a679 300 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 298 34.73 T 29-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 THSYN_RS27295 405a993b965576657cde229408bcce1e 114 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 31.204 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS27295 405a993b965576657cde229408bcce1e 114 PRINTS PR00061 Ribosomal protein L19 signature 34 63 2.3E-39 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS27295 405a993b965576657cde229408bcce1e 114 PRINTS PR00061 Ribosomal protein L19 signature 4 33 2.3E-39 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS27295 405a993b965576657cde229408bcce1e 114 PRINTS PR00061 Ribosomal protein L19 signature 88 113 2.3E-39 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS27295 405a993b965576657cde229408bcce1e 114 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 3.9E-50 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS27295 405a993b965576657cde229408bcce1e 114 Pfam PF01245 Ribosomal protein L19 3 113 3.2E-49 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS27295 405a993b965576657cde229408bcce1e 114 PIRSF PIRSF002191 1 114 1.4E-49 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS27295 405a993b965576657cde229408bcce1e 114 SUPERFAMILY SSF50104 2 113 2.71E-46 T 29-03-2018 IPR008991 Translation protein SH3-like domain THSYN_RS27295 405a993b965576657cde229408bcce1e 114 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 29-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS04860 20fe761fee75f347502663523189c906 396 PIRSF PIRSF000497 1 395 8.9E-165 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THSYN_RS04860 20fe761fee75f347502663523189c906 396 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 123 133 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THSYN_RS04860 20fe761fee75f347502663523189c906 396 SUPERFAMILY SSF55973 241 394 2.83E-64 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THSYN_RS04860 20fe761fee75f347502663523189c906 396 Pfam PF02772 S-adenosylmethionine synthetase, central domain 122 239 2.4E-44 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THSYN_RS04860 20fe761fee75f347502663523189c906 396 SUPERFAMILY SSF55973 4 116 3.22E-40 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THSYN_RS04860 20fe761fee75f347502663523189c906 396 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 394 55.033 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THSYN_RS04860 20fe761fee75f347502663523189c906 396 Gene3D G3DSA:3.30.300.10 267 396 2.0E-44 T 29-03-2018 THSYN_RS04860 20fe761fee75f347502663523189c906 396 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 267 275 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THSYN_RS04860 20fe761fee75f347502663523189c906 396 Gene3D G3DSA:3.30.300.10 149 266 1.2E-41 T 29-03-2018 THSYN_RS04860 20fe761fee75f347502663523189c906 396 Gene3D G3DSA:3.30.300.10 12 144 1.3E-39 T 29-03-2018 THSYN_RS04860 20fe761fee75f347502663523189c906 396 SUPERFAMILY SSF55973 118 240 1.29E-49 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THSYN_RS04860 20fe761fee75f347502663523189c906 396 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 393 1.2E-176 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THSYN_RS04860 20fe761fee75f347502663523189c906 396 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 241 383 4.7E-64 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THSYN_RS04860 20fe761fee75f347502663523189c906 396 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 107 1.7E-38 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THSYN_RS18750 8021b79736077bdbd211ebf3ff1653d0 325 PRINTS PR00111 Alpha/beta hydrolase fold signature 181 194 9.7E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS18750 8021b79736077bdbd211ebf3ff1653d0 325 PRINTS PR00111 Alpha/beta hydrolase fold signature 195 208 9.7E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS18750 8021b79736077bdbd211ebf3ff1653d0 325 PRINTS PR00111 Alpha/beta hydrolase fold signature 137 152 9.7E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS18750 8021b79736077bdbd211ebf3ff1653d0 325 Gene3D G3DSA:2.20.28.20 2 31 0.0016 T 29-03-2018 THSYN_RS18750 8021b79736077bdbd211ebf3ff1653d0 325 Gene3D G3DSA:3.40.50.1820 85 325 2.3E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS18750 8021b79736077bdbd211ebf3ff1653d0 325 SUPERFAMILY SSF53474 90 323 1.25E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS18750 8021b79736077bdbd211ebf3ff1653d0 325 Pfam PF00561 alpha/beta hydrolase fold 111 228 2.3E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS21935 7e19d242e89c003ff9ce64e6052404a0 188 SUPERFAMILY SSF52980 58 174 9.65E-11 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS21935 7e19d242e89c003ff9ce64e6052404a0 188 Gene3D G3DSA:3.90.1570.10 45 179 6.3E-22 T 29-03-2018 THSYN_RS21935 7e19d242e89c003ff9ce64e6052404a0 188 Pfam PF05685 Putative restriction endonuclease 54 160 9.6E-17 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS11750 78a942b4dc34953ca7f9d30c4cac1e41 528 Pfam PF14516 AAA-like domain 39 266 9.7E-9 T 29-03-2018 THSYN_RS11750 78a942b4dc34953ca7f9d30c4cac1e41 528 SUPERFAMILY SSF52540 26 283 2.23E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11750 78a942b4dc34953ca7f9d30c4cac1e41 528 Gene3D G3DSA:3.40.50.300 21 501 1.6E-9 T 29-03-2018 THSYN_RS29460 734fdd7af2f643bdfea08aa1386ee4b9 152 SMART SM00448 8 131 5.4E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS29460 734fdd7af2f643bdfea08aa1386ee4b9 152 SUPERFAMILY SSF52172 9 134 4.13E-30 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS29460 734fdd7af2f643bdfea08aa1386ee4b9 152 Gene3D G3DSA:3.40.50.2300 1 138 1.1E-27 T 29-03-2018 THSYN_RS29460 734fdd7af2f643bdfea08aa1386ee4b9 152 Pfam PF00072 Response regulator receiver domain 10 129 2.2E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS32170 b1b5fe8f163319013c0a0315c672cb6d 266 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 12 220 3.2E-38 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS32170 b1b5fe8f163319013c0a0315c672cb6d 266 PIRSF PIRSF036427 9 244 9.4E-53 T 29-03-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 THSYN_RS32170 b1b5fe8f163319013c0a0315c672cb6d 266 SUPERFAMILY SSF53790 6 245 9.81E-41 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS32170 b1b5fe8f163319013c0a0315c672cb6d 266 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 11 238 4.5E-63 T 29-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 THSYN_RS32170 b1b5fe8f163319013c0a0315c672cb6d 266 Gene3D G3DSA:3.40.1010.10 10 156 2.3E-24 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS23720 9a64dd38200b7054066e242a7d0f341d 396 PIRSF PIRSF001434 1 396 2.6E-145 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THSYN_RS23720 9a64dd38200b7054066e242a7d0f341d 396 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 393 3.8E-138 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THSYN_RS23720 9a64dd38200b7054066e242a7d0f341d 396 Gene3D G3DSA:3.40.640.10 8 261 3.1E-67 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS23720 9a64dd38200b7054066e242a7d0f341d 396 SUPERFAMILY SSF53383 28 394 1.28E-118 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS23720 9a64dd38200b7054066e242a7d0f341d 396 TIGRFAM TIGR01328 met_gam_lyase: methionine gamma-lyase 8 394 2.5E-171 T 29-03-2018 IPR006237 L-methionine gamma-lyase GO:0018826 KEGG: 00270+4.4.1.11|KEGG: 00450+4.4.1.11|KEGG: 00920+4.4.1.2|MetaCyc: PWY-7793 THSYN_RS23720 9a64dd38200b7054066e242a7d0f341d 396 Gene3D G3DSA:3.90.1150.10 263 396 6.1E-49 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS23720 9a64dd38200b7054066e242a7d0f341d 396 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THSYN_RS06070 8e994e92134745aa5242c487f554d96a 377 SUPERFAMILY SSF53756 8 367 1.41E-63 T 29-03-2018 THSYN_RS06070 8e994e92134745aa5242c487f554d96a 377 Gene3D G3DSA:3.40.50.2000 187 355 4.6E-37 T 29-03-2018 THSYN_RS06070 8e994e92134745aa5242c487f554d96a 377 Gene3D G3DSA:3.40.50.2000 1 186 3.3E-8 T 29-03-2018 THSYN_RS06070 8e994e92134745aa5242c487f554d96a 377 Pfam PF13692 Glycosyl transferases group 1 202 341 3.1E-28 T 29-03-2018 THSYN_RS06070 8e994e92134745aa5242c487f554d96a 377 Pfam PF13439 Glycosyltransferase Family 4 22 178 2.0E-14 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS12860 acf677c11bf9215c4850dd6c00fa7cf6 106 Pfam PF01909 Nucleotidyltransferase domain 17 83 9.0E-8 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS12860 acf677c11bf9215c4850dd6c00fa7cf6 106 Gene3D G3DSA:3.30.460.10 2 105 4.0E-15 T 29-03-2018 THSYN_RS12860 acf677c11bf9215c4850dd6c00fa7cf6 106 SUPERFAMILY SSF81301 8 106 3.27E-15 T 29-03-2018 THSYN_RS06295 27d5fcd8ab635be39680eee494ebaf48 589 SUPERFAMILY SSF56645 39 276 1.57E-57 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THSYN_RS06295 27d5fcd8ab635be39680eee494ebaf48 589 SUPERFAMILY SSF47203 284 461 4.35E-44 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THSYN_RS06295 27d5fcd8ab635be39680eee494ebaf48 589 Gene3D G3DSA:1.20.140.10 269 457 2.1E-43 T 29-03-2018 THSYN_RS06295 27d5fcd8ab635be39680eee494ebaf48 589 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 279 441 7.6E-26 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THSYN_RS06295 27d5fcd8ab635be39680eee494ebaf48 589 Gene3D G3DSA:2.40.110.10 156 268 5.6E-24 T 29-03-2018 THSYN_RS06295 27d5fcd8ab635be39680eee494ebaf48 589 Gene3D G3DSA:1.10.540.10 30 155 9.1E-17 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 THSYN_RS06295 27d5fcd8ab635be39680eee494ebaf48 589 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 53 156 1.9E-10 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 THSYN_RS06295 27d5fcd8ab635be39680eee494ebaf48 589 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 458 584 1.3E-27 T 29-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain THSYN_RS06295 27d5fcd8ab635be39680eee494ebaf48 589 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 269 4.1E-13 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 THSYN_RS07950 13169761f88e3ff91a38973ea6e8a728 485 Pfam PF02384 N-6 DNA Methylase 123 421 1.8E-64 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS07950 13169761f88e3ff91a38973ea6e8a728 485 Gene3D G3DSA:3.40.50.150 144 441 5.7E-48 T 29-03-2018 THSYN_RS07950 13169761f88e3ff91a38973ea6e8a728 485 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 295 319 1.6E-22 T 29-03-2018 THSYN_RS07950 13169761f88e3ff91a38973ea6e8a728 485 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 170 184 1.6E-22 T 29-03-2018 THSYN_RS07950 13169761f88e3ff91a38973ea6e8a728 485 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 146 162 1.6E-22 T 29-03-2018 THSYN_RS07950 13169761f88e3ff91a38973ea6e8a728 485 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 253 265 1.6E-22 T 29-03-2018 THSYN_RS07950 13169761f88e3ff91a38973ea6e8a728 485 SUPERFAMILY SSF53335 5 481 2.67E-112 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS07950 13169761f88e3ff91a38973ea6e8a728 485 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 256 262 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS07950 13169761f88e3ff91a38973ea6e8a728 485 Pfam PF12161 HsdM N-terminal domain 7 113 1.2E-11 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS10225 59279f2f354952e2d63b83935e311379 159 Pfam PF01584 CheW-like domain 24 149 3.4E-11 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS10225 59279f2f354952e2d63b83935e311379 159 Gene3D G3DSA:2.40.50.180 30 101 0.0012 T 29-03-2018 THSYN_RS10225 59279f2f354952e2d63b83935e311379 159 SUPERFAMILY SSF50341 24 150 5.89E-10 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS10225 59279f2f354952e2d63b83935e311379 159 SMART SM00260 9 149 0.004 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS13105 d331d6dcb944128f41ce14b78c5f7506 808 Pfam PF00912 Transglycosylase 49 223 1.1E-59 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 THSYN_RS13105 d331d6dcb944128f41ce14b78c5f7506 808 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 59 719 7.5E-177 T 29-03-2018 THSYN_RS13105 d331d6dcb944128f41ce14b78c5f7506 808 SUPERFAMILY SSF56601 205 227 1.18E-121 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS13105 d331d6dcb944128f41ce14b78c5f7506 808 SUPERFAMILY SSF56601 256 307 1.18E-121 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS13105 d331d6dcb944128f41ce14b78c5f7506 808 SUPERFAMILY SSF56601 625 752 1.18E-121 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS13105 d331d6dcb944128f41ce14b78c5f7506 808 SUPERFAMILY SSF56601 414 597 1.18E-121 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS13105 d331d6dcb944128f41ce14b78c5f7506 808 Pfam PF00905 Penicillin binding protein transpeptidase domain 420 680 3.5E-26 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THSYN_RS13105 d331d6dcb944128f41ce14b78c5f7506 808 SUPERFAMILY SSF53955 37 247 1.74E-72 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS13105 d331d6dcb944128f41ce14b78c5f7506 808 Gene3D G3DSA:3.40.710.10 236 733 2.4E-119 T 29-03-2018 THSYN_RS13105 d331d6dcb944128f41ce14b78c5f7506 808 Pfam PF17092 Penicillin-binding protein OB-like domain 310 417 3.8E-20 T 29-03-2018 IPR031376 Penicillin-binding protein, OB-like domain THSYN_RS13105 d331d6dcb944128f41ce14b78c5f7506 808 Gene3D G3DSA:1.10.3810.10 42 235 2.9E-75 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 THSYN_RS14310 3150f7b73c61ad57dc215051ef33df17 103 SUPERFAMILY SSF46785 3 93 1.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS14310 3150f7b73c61ad57dc215051ef33df17 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 6.7E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS14310 3150f7b73c61ad57dc215051ef33df17 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 6.7E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS14310 3150f7b73c61ad57dc215051ef33df17 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 6.7E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS14310 3150f7b73c61ad57dc215051ef33df17 103 Pfam PF12840 Helix-turn-helix domain 9 69 3.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS14310 3150f7b73c61ad57dc215051ef33df17 103 SMART SM00418 8 89 1.1E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS14310 3150f7b73c61ad57dc215051ef33df17 103 Gene3D G3DSA:1.10.10.10 1 90 6.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 Gene3D G3DSA:3.40.50.1440 8 214 1.5E-41 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 SUPERFAMILY SSF52490 14 205 1.44E-68 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 SMART SM00865 207 325 1.5E-55 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 Pfam PF12327 FtsZ family, C-terminal domain 222 316 1.5E-36 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 323 7.9E-131 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 SUPERFAMILY SSF55307 204 318 2.98E-42 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 PRINTS PR00423 Cell division protein FtsZ signature 98 118 6.1E-50 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 PRINTS PR00423 Cell division protein FtsZ signature 126 147 6.1E-50 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 PRINTS PR00423 Cell division protein FtsZ signature 212 233 6.1E-50 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 PRINTS PR00423 Cell division protein FtsZ signature 189 211 6.1E-50 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 172 2.1E-38 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 Gene3D G3DSA:3.30.1330.20 215 322 1.8E-43 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 SMART SM00864 13 205 9.8E-113 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS03585 9c4a3c8cd0c3ba899c0661a3841a4987 389 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 344 37.916 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 THSYN_RS28680 19dff361fc47a442481e4c234be7ed6e 318 Gene3D G3DSA:3.40.710.10 73 312 1.9E-18 T 29-03-2018 THSYN_RS28680 19dff361fc47a442481e4c234be7ed6e 318 SUPERFAMILY SSF56601 74 282 9.73E-23 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS28680 19dff361fc47a442481e4c234be7ed6e 318 Pfam PF13354 Beta-lactamase enzyme family 128 264 3.2E-14 T 29-03-2018 THSYN_RS10220 8effec194d4b33e3f3a0eec0f174f1d1 1278 SUPERFAMILY SSF47226 670 790 9.94E-16 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10220 8effec194d4b33e3f3a0eec0f174f1d1 1278 Gene3D G3DSA:2.30.30.40 1180 1243 9.0E-11 T 29-03-2018 THSYN_RS10220 8effec194d4b33e3f3a0eec0f174f1d1 1278 SUPERFAMILY SSF47226 461 573 3.14E-25 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10220 8effec194d4b33e3f3a0eec0f174f1d1 1278 Pfam PF01627 Hpt domain 672 762 4.8E-11 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10220 8effec194d4b33e3f3a0eec0f174f1d1 1278 Pfam PF01627 Hpt domain 462 551 1.8E-13 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10220 8effec194d4b33e3f3a0eec0f174f1d1 1278 Pfam PF01584 CheW-like domain 1113 1245 1.2E-11 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS10220 8effec194d4b33e3f3a0eec0f174f1d1 1278 SUPERFAMILY SSF50341 1111 1242 8.11E-16 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS10220 8effec194d4b33e3f3a0eec0f174f1d1 1278 SMART SM00260 1104 1243 1.1E-10 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS10220 8effec194d4b33e3f3a0eec0f174f1d1 1278 SMART SM00073 460 557 1.3E-7 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10220 8effec194d4b33e3f3a0eec0f174f1d1 1278 SMART SM00073 670 765 3.8E-5 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10220 8effec194d4b33e3f3a0eec0f174f1d1 1278 Gene3D G3DSA:1.20.120.160 667 800 2.4E-17 T 29-03-2018 THSYN_RS10220 8effec194d4b33e3f3a0eec0f174f1d1 1278 Gene3D G3DSA:1.20.120.160 460 592 3.7E-26 T 29-03-2018 THSYN_RS10220 8effec194d4b33e3f3a0eec0f174f1d1 1278 SUPERFAMILY SSF47226 10 127 1.0E-4 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS22240 54ff3527f3b970b45f8acb03630d01d0 84 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 84 8.0E-23 T 29-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 THSYN_RS22240 54ff3527f3b970b45f8acb03630d01d0 84 Pfam PF02597 ThiS family 4 84 7.5E-21 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 THSYN_RS22240 54ff3527f3b970b45f8acb03630d01d0 84 Gene3D G3DSA:3.10.20.30 2 84 1.1E-21 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS22240 54ff3527f3b970b45f8acb03630d01d0 84 SUPERFAMILY SSF54285 1 82 9.0E-21 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THSYN_RS23755 32acdc7e28d3f0cc9ac07f2c9f0881a9 1235 SUPERFAMILY SSF52540 442 673 4.6E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23755 32acdc7e28d3f0cc9ac07f2c9f0881a9 1235 Gene3D G3DSA:3.40.50.1460 83 405 2.5E-18 T 29-03-2018 THSYN_RS23755 32acdc7e28d3f0cc9ac07f2c9f0881a9 1235 SUPERFAMILY SSF48452 990 1175 5.01E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23755 32acdc7e28d3f0cc9ac07f2c9f0881a9 1235 Gene3D G3DSA:1.25.40.10 1106 1230 3.1E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23755 32acdc7e28d3f0cc9ac07f2c9f0881a9 1235 SMART SM00028 1027 1063 39.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23755 32acdc7e28d3f0cc9ac07f2c9f0881a9 1235 SMART SM00028 1123 1156 0.047 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23755 32acdc7e28d3f0cc9ac07f2c9f0881a9 1235 Gene3D G3DSA:1.25.40.10 1031 1105 3.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23755 32acdc7e28d3f0cc9ac07f2c9f0881a9 1235 Gene3D G3DSA:3.40.50.300 433 613 1.1E-4 T 29-03-2018 THSYN_RS23755 32acdc7e28d3f0cc9ac07f2c9f0881a9 1235 Pfam PF13181 Tetratricopeptide repeat 1125 1154 0.013 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23755 32acdc7e28d3f0cc9ac07f2c9f0881a9 1235 Gene3D G3DSA:3.30.70.100 935 1030 0.049 T 29-03-2018 THSYN_RS23755 32acdc7e28d3f0cc9ac07f2c9f0881a9 1235 Pfam PF12770 CHAT domain 211 391 4.5E-14 T 29-03-2018 IPR024983 CHAT domain THSYN_RS26775 88ad360a36c6a7f6b6d02d208f1d260a 141 Pfam PF01850 PIN domain 2 121 7.5E-12 T 29-03-2018 IPR002716 PIN domain THSYN_RS26775 88ad360a36c6a7f6b6d02d208f1d260a 141 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 132 10.101 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS26775 88ad360a36c6a7f6b6d02d208f1d260a 141 Gene3D G3DSA:3.40.50.1010 1 139 1.0E-24 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS26775 88ad360a36c6a7f6b6d02d208f1d260a 141 SUPERFAMILY SSF88723 2 137 2.16E-27 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS30320 02cf4d267268d3975dbe4e8450402225 440 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 420 6.6E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS30320 02cf4d267268d3975dbe4e8450402225 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 412 3.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS30320 02cf4d267268d3975dbe4e8450402225 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 377 3.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS30320 02cf4d267268d3975dbe4e8450402225 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 432 3.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS30320 02cf4d267268d3975dbe4e8450402225 440 SMART SM00387 328 435 1.9E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS30320 02cf4d267268d3975dbe4e8450402225 440 SUPERFAMILY SSF55874 300 433 1.96E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS30320 02cf4d267268d3975dbe4e8450402225 440 Gene3D G3DSA:3.30.565.10 184 434 2.2E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS28160 8a5f7766695109132e43ba9e80d53e66 988 SUPERFAMILY SSF51998 591 979 4.58E-107 T 29-03-2018 THSYN_RS28160 8a5f7766695109132e43ba9e80d53e66 988 SUPERFAMILY SSF51294 280 355 6.28E-6 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS28160 8a5f7766695109132e43ba9e80d53e66 988 Gene3D G3DSA:3.20.70.20 492 986 2.3E-130 T 29-03-2018 THSYN_RS28160 8a5f7766695109132e43ba9e80d53e66 988 Gene3D G3DSA:3.20.70.20 144 287 3.0E-46 T 29-03-2018 THSYN_RS28160 8a5f7766695109132e43ba9e80d53e66 988 SUPERFAMILY SSF51998 133 302 1.01E-40 T 29-03-2018 THSYN_RS28160 8a5f7766695109132e43ba9e80d53e66 988 Pfam PF03477 ATP cone domain 14 103 2.3E-19 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 THSYN_RS28160 8a5f7766695109132e43ba9e80d53e66 988 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 133 281 3.4E-48 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 THSYN_RS28160 8a5f7766695109132e43ba9e80d53e66 988 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 588 978 2.3E-111 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 THSYN_RS28160 8a5f7766695109132e43ba9e80d53e66 988 Gene3D G3DSA:3.10.28.10 384 491 0.0013 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 THSYN_RS28160 8a5f7766695109132e43ba9e80d53e66 988 SUPERFAMILY SSF55608 476 565 5.67E-9 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 THSYN_RS03590 7009cf4740af3363bd9b114acbe86535 303 Gene3D G3DSA:3.30.1700.10 128 298 1.5E-69 T 29-03-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 THSYN_RS03590 7009cf4740af3363bd9b114acbe86535 303 SUPERFAMILY SSF54211 133 277 3.79E-53 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS03590 7009cf4740af3363bd9b114acbe86535 303 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 275 1.0E-109 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 THSYN_RS03590 7009cf4740af3363bd9b114acbe86535 303 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 297 6.3E-124 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 THSYN_RS03590 7009cf4740af3363bd9b114acbe86535 303 SUPERFAMILY SSF54211 3 125 1.37E-42 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS03590 7009cf4740af3363bd9b114acbe86535 303 Gene3D G3DSA:3.30.230.20 1 127 7.2E-51 T 29-03-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 THSYN_RS03590 7009cf4740af3363bd9b114acbe86535 303 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 279 46.895 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 THSYN_RS06750 bf5161671e93adbf9ed8a33706445c47 679 SMART SM00448 146 259 1.3E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS06750 bf5161671e93adbf9ed8a33706445c47 679 SMART SM00052 431 671 1.5E-11 T 29-03-2018 IPR001633 EAL domain THSYN_RS06750 bf5161671e93adbf9ed8a33706445c47 679 Gene3D G3DSA:3.20.20.450 437 676 2.0E-36 T 29-03-2018 IPR001633 EAL domain THSYN_RS06750 bf5161671e93adbf9ed8a33706445c47 679 SUPERFAMILY SSF141868 439 671 2.48E-32 T 29-03-2018 IPR001633 EAL domain THSYN_RS06750 bf5161671e93adbf9ed8a33706445c47 679 Gene3D G3DSA:3.40.50.2300 144 351 7.7E-33 T 29-03-2018 THSYN_RS06750 bf5161671e93adbf9ed8a33706445c47 679 SUPERFAMILY SSF52172 145 274 3.42E-32 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS06750 bf5161671e93adbf9ed8a33706445c47 679 Pfam PF00563 EAL domain 440 666 8.2E-28 T 29-03-2018 IPR001633 EAL domain THSYN_RS06750 bf5161671e93adbf9ed8a33706445c47 679 Pfam PF00072 Response regulator receiver domain 148 259 3.2E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS06750 bf5161671e93adbf9ed8a33706445c47 679 Gene3D G3DSA:3.40.50.2300 13 143 0.21 T 29-03-2018 THSYN_RS12835 6bfca63fe08c71b72190adcaa9ffdaa3 177 Pfam PF17200 Single Cache domain 2 49 150 1.6E-15 T 29-03-2018 IPR033480 Single Cache domain 2 THSYN_RS12835 6bfca63fe08c71b72190adcaa9ffdaa3 177 SMART SM01049 41 136 4.1E-18 T 29-03-2018 IPR033480 Single Cache domain 2 THSYN_RS12835 6bfca63fe08c71b72190adcaa9ffdaa3 177 Gene3D G3DSA:3.30.450.20 25 157 6.5E-20 T 29-03-2018 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 SUPERFAMILY SSF52540 170 418 3.92E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 Gene3D G3DSA:1.10.8.60 353 437 1.2E-29 T 29-03-2018 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 SMART SM01086 655 744 1.4E-33 T 29-03-2018 IPR019489 Clp ATPase, C-terminal THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 655 735 4.7E-23 T 29-03-2018 IPR019489 Clp ATPase, C-terminal THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 SUPERFAMILY SSF81923 1 141 1.02E-60 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 735 0.0 T 29-03-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 Gene3D G3DSA:3.40.50.300 444 654 1.4E-44 T 29-03-2018 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 1.2E-15 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 Gene3D G3DSA:1.10.8.60 655 752 9.1E-20 T 29-03-2018 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 520 538 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 597 611 1.2E-37 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 564 582 1.2E-37 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 535 553 1.2E-37 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 493 511 1.2E-37 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 Gene3D G3DSA:1.10.1780.10 1 151 8.1E-28 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 Pfam PF07724 AAA domain (Cdc48 subfamily) 488 648 4.2E-48 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 Gene3D G3DSA:3.40.50.300 167 352 8.1E-27 T 29-03-2018 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 SMART SM00382 208 353 2.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 SMART SM00382 489 656 7.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 SUPERFAMILY SSF52540 439 731 2.46E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 213 326 2.6E-11 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS03970 f34779ae57c9ad65ddd10228d3615eb7 753 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 304 316 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 THSYN_RS23665 45395f88e021ddc361e1048892175de3 301 Pfam PF01841 Transglutaminase-like superfamily 146 248 8.8E-14 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS23665 45395f88e021ddc361e1048892175de3 301 SUPERFAMILY SSF54001 143 275 1.68E-23 T 29-03-2018 THSYN_RS23665 45395f88e021ddc361e1048892175de3 301 SMART SM00460 175 250 5.7E-8 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS23665 45395f88e021ddc361e1048892175de3 301 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 3 81 2.4E-12 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal THSYN_RS13700 55e6444382f6eabc5a88a89d4b260ad0 2985 SMART SM00635 973 1055 6.9E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 THSYN_RS13700 55e6444382f6eabc5a88a89d4b260ad0 2985 SMART SM00635 1060 1142 3.9E-10 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 THSYN_RS13700 55e6444382f6eabc5a88a89d4b260ad0 2985 Gene3D G3DSA:2.60.40.10 686 777 2.0E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS13700 55e6444382f6eabc5a88a89d4b260ad0 2985 Gene3D G3DSA:2.60.40.10 32 96 0.012 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS13700 55e6444382f6eabc5a88a89d4b260ad0 2985 Gene3D G3DSA:2.60.40.1080 1059 1136 6.9E-9 T 29-03-2018 THSYN_RS13700 55e6444382f6eabc5a88a89d4b260ad0 2985 Gene3D G3DSA:2.60.40.1080 981 1058 4.7E-10 T 29-03-2018 THSYN_RS13700 55e6444382f6eabc5a88a89d4b260ad0 2985 Gene3D G3DSA:2.60.40.10 325 439 1.2E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS13700 55e6444382f6eabc5a88a89d4b260ad0 2985 Gene3D G3DSA:2.40.50.70 556 617 0.021 T 29-03-2018 THSYN_RS13700 55e6444382f6eabc5a88a89d4b260ad0 2985 Gene3D G3DSA:2.40.50.70 1240 1290 8.7E-5 T 29-03-2018 THSYN_RS13700 55e6444382f6eabc5a88a89d4b260ad0 2985 Gene3D G3DSA:2.40.50.70 1137 1188 3.2E-5 T 29-03-2018 THSYN_RS13700 55e6444382f6eabc5a88a89d4b260ad0 2985 Pfam PF13205 Bacterial Ig-like domain 464 568 1.4E-7 T 29-03-2018 IPR032812 SbsA, Ig-like domain THSYN_RS13700 55e6444382f6eabc5a88a89d4b260ad0 2985 Pfam PF02368 Bacterial Ig-like domain (group 2) 1062 1126 1.2E-5 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 THSYN_RS03225 4274ba9b6abadecaca6a1be32a8c7bce 136 Pfam PF01850 PIN domain 4 127 1.2E-12 T 29-03-2018 IPR002716 PIN domain THSYN_RS03225 4274ba9b6abadecaca6a1be32a8c7bce 136 Gene3D G3DSA:3.40.50.1010 2 136 4.3E-27 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS03225 4274ba9b6abadecaca6a1be32a8c7bce 136 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 133 10.759 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS03225 4274ba9b6abadecaca6a1be32a8c7bce 136 SUPERFAMILY SSF88723 1 134 1.01E-32 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS15335 4e44b77316d889c62625b7c9a6e2614c 1012 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 238 878 1.9E-54 T 29-03-2018 IPR013407 CRISPR-associated protein Cmr2 THSYN_RS15335 4e44b77316d889c62625b7c9a6e2614c 1012 Pfam PF12469 CRISPR-associated protein 238 358 5.3E-31 T 29-03-2018 IPR024615 CRISPR-associated protein Cmr2, N-terminal THSYN_RS02075 81cbbe9f2bc2365328e528ba46b93c73 190 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 2 156 7.9E-26 T 29-03-2018 IPR010664 Lipopolysaccharide assembly, LptC-related THSYN_RS02075 81cbbe9f2bc2365328e528ba46b93c73 190 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 2 156 2.5E-33 T 29-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 THSYN_RS21070 90b05742abcedb0ae0d66a9b8f9d6ba8 518 PRINTS PR01806 Virulence factor MviN signature 53 69 1.7E-77 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THSYN_RS21070 90b05742abcedb0ae0d66a9b8f9d6ba8 518 PRINTS PR01806 Virulence factor MviN signature 158 179 1.7E-77 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THSYN_RS21070 90b05742abcedb0ae0d66a9b8f9d6ba8 518 PRINTS PR01806 Virulence factor MviN signature 134 158 1.7E-77 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THSYN_RS21070 90b05742abcedb0ae0d66a9b8f9d6ba8 518 PRINTS PR01806 Virulence factor MviN signature 418 435 1.7E-77 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THSYN_RS21070 90b05742abcedb0ae0d66a9b8f9d6ba8 518 PRINTS PR01806 Virulence factor MviN signature 366 385 1.7E-77 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THSYN_RS21070 90b05742abcedb0ae0d66a9b8f9d6ba8 518 PRINTS PR01806 Virulence factor MviN signature 34 53 1.7E-77 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THSYN_RS21070 90b05742abcedb0ae0d66a9b8f9d6ba8 518 PRINTS PR01806 Virulence factor MviN signature 260 286 1.7E-77 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THSYN_RS21070 90b05742abcedb0ae0d66a9b8f9d6ba8 518 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 4 475 20.169 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THSYN_RS21070 90b05742abcedb0ae0d66a9b8f9d6ba8 518 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 3 508 4.2E-136 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THSYN_RS21070 90b05742abcedb0ae0d66a9b8f9d6ba8 518 PIRSF PIRSF002869 1 517 1.0E-159 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THSYN_RS21070 90b05742abcedb0ae0d66a9b8f9d6ba8 518 Pfam PF03023 MviN-like protein 29 470 4.9E-138 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THSYN_RS26140 a31ad5b520d1050888c44471066a6513 640 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 188 320 1.7E-46 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS26140 a31ad5b520d1050888c44471066a6513 640 Gene3D G3DSA:3.40.50.300 130 337 2.1E-64 T 29-03-2018 THSYN_RS26140 a31ad5b520d1050888c44471066a6513 640 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 622 38.09 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 THSYN_RS26140 a31ad5b520d1050888c44471066a6513 640 Pfam PF01434 Peptidase family M41 382 592 1.1E-84 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 THSYN_RS26140 a31ad5b520d1050888c44471066a6513 640 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 98 593 3.1E-246 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 THSYN_RS26140 a31ad5b520d1050888c44471066a6513 640 SUPERFAMILY SSF52540 142 391 1.94E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26140 a31ad5b520d1050888c44471066a6513 640 ProSitePatterns PS00674 AAA-protein family signature. 291 309 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 THSYN_RS26140 a31ad5b520d1050888c44471066a6513 640 SMART SM00382 184 323 1.1E-26 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS26140 a31ad5b520d1050888c44471066a6513 640 Gene3D G3DSA:1.10.8.60 338 414 1.1E-24 T 29-03-2018 THSYN_RS26140 a31ad5b520d1050888c44471066a6513 640 Pfam PF06480 FtsH Extracellular 5 83 2.7E-14 T 29-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 THSYN_RS26140 a31ad5b520d1050888c44471066a6513 640 SUPERFAMILY SSF140990 402 604 6.54E-78 T 29-03-2018 THSYN_RS17065 eef825bbd1ffc33aaea1277a02c30bdd 379 Gene3D G3DSA:3.40.50.2000 194 359 1.0E-16 T 29-03-2018 THSYN_RS17065 eef825bbd1ffc33aaea1277a02c30bdd 379 Pfam PF13692 Glycosyl transferases group 1 217 343 1.3E-9 T 29-03-2018 THSYN_RS17065 eef825bbd1ffc33aaea1277a02c30bdd 379 SUPERFAMILY SSF53756 116 375 5.76E-21 T 29-03-2018 THSYN_RS17065 eef825bbd1ffc33aaea1277a02c30bdd 379 SUPERFAMILY SSF53756 11 58 5.76E-21 T 29-03-2018 THSYN_RS24570 66f3c8f02eec9d0ad0ea9b093359e56e 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 7.2E-5 T 29-03-2018 THSYN_RS24570 66f3c8f02eec9d0ad0ea9b093359e56e 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 413 432 7.2E-5 T 29-03-2018 THSYN_RS24570 66f3c8f02eec9d0ad0ea9b093359e56e 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 7.2E-5 T 29-03-2018 THSYN_RS24570 66f3c8f02eec9d0ad0ea9b093359e56e 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 308 320 7.2E-5 T 29-03-2018 THSYN_RS24570 66f3c8f02eec9d0ad0ea9b093359e56e 478 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 470 18.423 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 THSYN_RS24570 66f3c8f02eec9d0ad0ea9b093359e56e 478 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 469 1.5E-142 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 THSYN_RS24570 66f3c8f02eec9d0ad0ea9b093359e56e 478 Pfam PF00361 Proton-conducting membrane transporter 125 419 7.7E-77 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS31425 4f58eb303db2679e1a769c711d34a7ab 489 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 1 485 1.3E-184 T 29-03-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 THSYN_RS31425 4f58eb303db2679e1a769c711d34a7ab 489 SUPERFAMILY SSF51905 1 313 1.58E-68 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31425 4f58eb303db2679e1a769c711d34a7ab 489 SUPERFAMILY SSF51905 444 476 1.58E-68 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31425 4f58eb303db2679e1a769c711d34a7ab 489 Gene3D G3DSA:3.50.50.60 1 478 1.2E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31425 4f58eb303db2679e1a769c711d34a7ab 489 Pfam PF01593 Flavin containing amine oxidoreductase 8 476 1.3E-30 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THSYN_RS25185 fe897ecfb76ab099286644c9f2be5641 256 Gene3D G3DSA:3.90.550.10 5 253 1.5E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS25185 fe897ecfb76ab099286644c9f2be5641 256 SUPERFAMILY SSF53448 18 246 1.37E-19 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS25185 fe897ecfb76ab099286644c9f2be5641 256 Pfam PF00483 Nucleotidyl transferase 25 207 6.3E-9 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THSYN_RS25185 fe897ecfb76ab099286644c9f2be5641 256 PIRSF PIRSF028162 5 245 1.8E-51 T 29-03-2018 IPR016873 Capsular polysaccharide biosynthesis protein, BcbE, predicted THSYN_RS20725 4921dc73b708c9c29aef40a774af905c 226 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 9 219 4.3E-52 T 29-03-2018 THSYN_RS17210 41d7f0311b58ae67e8837c94c909e1ac 214 SUPERFAMILY SSF46626 38 165 6.4E-24 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS17210 41d7f0311b58ae67e8837c94c909e1ac 214 PIRSF PIRSF000005 1 214 9.0E-60 T 29-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 THSYN_RS17210 41d7f0311b58ae67e8837c94c909e1ac 214 SUPERFAMILY SSF46626 141 212 4.05E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS17210 41d7f0311b58ae67e8837c94c909e1ac 214 Gene3D G3DSA:1.10.760.10 112 211 2.4E-20 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS17210 41d7f0311b58ae67e8837c94c909e1ac 214 Gene3D G3DSA:1.10.760.10 16 111 5.1E-20 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS17210 41d7f0311b58ae67e8837c94c909e1ac 214 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 36 108 1.4E-6 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS17210 41d7f0311b58ae67e8837c94c909e1ac 214 Pfam PF00034 Cytochrome c 142 212 5.3E-5 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS12890 82f03e42379f5d9039f30e0dd0033e52 745 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 388 402 - T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 THSYN_RS12890 82f03e42379f5d9039f30e0dd0033e52 745 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 606 731 4.5E-46 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 THSYN_RS12890 82f03e42379f5d9039f30e0dd0033e52 745 Gene3D G3DSA:3.90.1150.10 455 629 2.0E-71 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS12890 82f03e42379f5d9039f30e0dd0033e52 745 Gene3D G3DSA:3.40.640.10 149 453 4.2E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS12890 82f03e42379f5d9039f30e0dd0033e52 745 SUPERFAMILY SSF55904 601 744 9.15E-43 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 THSYN_RS12890 82f03e42379f5d9039f30e0dd0033e52 745 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 20 143 4.4E-36 T 29-03-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 THSYN_RS12890 82f03e42379f5d9039f30e0dd0033e52 745 PIRSF PIRSF009393 1 745 8.8E-274 T 29-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 THSYN_RS12890 82f03e42379f5d9039f30e0dd0033e52 745 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 149 579 4.0E-147 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 THSYN_RS12890 82f03e42379f5d9039f30e0dd0033e52 745 SUPERFAMILY SSF53383 149 598 2.45E-115 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS12890 82f03e42379f5d9039f30e0dd0033e52 745 Gene3D G3DSA:3.40.50.220 78 147 0.047 T 29-03-2018 IPR027464 Ornithine decarboxylase, N-terminal domain KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 THSYN_RS12890 82f03e42379f5d9039f30e0dd0033e52 745 Gene3D G3DSA:3.90.100.10 630 745 1.0E-33 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 THSYN_RS27865 67640b582bf0e09bc2a5ca30f5492da7 132 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 2 120 22.424 T 29-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 THSYN_RS27865 67640b582bf0e09bc2a5ca30f5492da7 132 SUPERFAMILY SSF50685 19 111 1.71E-12 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain THSYN_RS27865 67640b582bf0e09bc2a5ca30f5492da7 132 Pfam PF03330 Lytic transglycolase 28 116 8.0E-24 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain THSYN_RS27865 67640b582bf0e09bc2a5ca30f5492da7 132 Gene3D G3DSA:2.40.40.10 9 122 4.9E-24 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain THSYN_RS27865 67640b582bf0e09bc2a5ca30f5492da7 132 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 30 129 2.8E-41 T 29-03-2018 IPR012997 Rare lipoprotein A THSYN_RS07365 22aa24871381b3e8a1a95a85bd6c62f9 326 Gene3D G3DSA:3.30.470.30 90 174 1.1E-15 T 29-03-2018 THSYN_RS07365 22aa24871381b3e8a1a95a85bd6c62f9 326 Pfam PF14743 DNA ligase OB-like domain 252 315 6.8E-24 T 29-03-2018 IPR029319 DNA ligase, OB-like domain THSYN_RS07365 22aa24871381b3e8a1a95a85bd6c62f9 326 Gene3D G3DSA:3.30.1490.70 175 226 9.9E-9 T 29-03-2018 THSYN_RS07365 22aa24871381b3e8a1a95a85bd6c62f9 326 Gene3D G3DSA:2.40.50.140 227 318 3.0E-17 T 29-03-2018 THSYN_RS07365 22aa24871381b3e8a1a95a85bd6c62f9 326 SUPERFAMILY SSF56091 67 237 2.16E-34 T 29-03-2018 THSYN_RS07365 22aa24871381b3e8a1a95a85bd6c62f9 326 SUPERFAMILY SSF50249 212 315 2.8E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS27210 ccddd3ea2c809557b1e31da0c024cf6f 38 Gene3D G3DSA:3.90.1580.10 1 38 1.2E-11 T 29-03-2018 THSYN_RS27210 ccddd3ea2c809557b1e31da0c024cf6f 38 SUPERFAMILY SSF56436 7 35 6.97E-10 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS27210 ccddd3ea2c809557b1e31da0c024cf6f 38 Pfam PF03781 Sulfatase-modifying factor enzyme 1 5 34 3.4E-10 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS23870 83b32c989f13abbceb59b6bf6b8337e0 86 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 8 83 24.001 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23870 83b32c989f13abbceb59b6bf6b8337e0 86 SUPERFAMILY SSF50249 8 85 7.28E-32 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS23870 83b32c989f13abbceb59b6bf6b8337e0 86 Pfam PF00366 Ribosomal protein S17 13 80 3.4E-32 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23870 83b32c989f13abbceb59b6bf6b8337e0 86 PRINTS PR00973 Ribosomal protein S17 family signature 69 76 5.4E-13 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23870 83b32c989f13abbceb59b6bf6b8337e0 86 PRINTS PR00973 Ribosomal protein S17 family signature 27 50 5.4E-13 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23870 83b32c989f13abbceb59b6bf6b8337e0 86 PRINTS PR00973 Ribosomal protein S17 family signature 59 69 5.4E-13 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23870 83b32c989f13abbceb59b6bf6b8337e0 86 Gene3D G3DSA:2.40.50.140 8 85 1.3E-31 T 29-03-2018 THSYN_RS23870 83b32c989f13abbceb59b6bf6b8337e0 86 ProSitePatterns PS00056 Ribosomal protein S17 signature. 59 71 - T 29-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23870 83b32c989f13abbceb59b6bf6b8337e0 86 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 9 79 2.0E-26 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23870 83b32c989f13abbceb59b6bf6b8337e0 86 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 9 78 3.0E-35 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS29010 1a994c3f2873194fd5c0d8e51c4f88f9 429 SUPERFAMILY SSF53335 74 264 2.81E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS29010 1a994c3f2873194fd5c0d8e51c4f88f9 429 Gene3D G3DSA:3.40.50.150 68 266 8.2E-25 T 29-03-2018 THSYN_RS29010 1a994c3f2873194fd5c0d8e51c4f88f9 429 Pfam PF13489 Methyltransferase domain 105 245 8.2E-19 T 29-03-2018 THSYN_RS29010 1a994c3f2873194fd5c0d8e51c4f88f9 429 Pfam PF08484 C-methyltransferase C-terminal domain 255 414 1.9E-45 T 29-03-2018 IPR013691 C-methyltransferase THSYN_RS29010 1a994c3f2873194fd5c0d8e51c4f88f9 429 Pfam PF08421 Putative zinc binding domain 14 74 1.1E-16 T 29-03-2018 IPR013630 Methyltransferase putative zinc binding domain THSYN_RS13670 ee82f3beb0f889101c6d9f63364a5d19 334 Gene3D G3DSA:3.30.930.10 17 334 2.0E-50 T 29-03-2018 THSYN_RS13670 ee82f3beb0f889101c6d9f63364a5d19 334 PRINTS PR00982 Lysyl-tRNA synthetase signature 38 48 1.2E-5 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THSYN_RS13670 ee82f3beb0f889101c6d9f63364a5d19 334 PRINTS PR00982 Lysyl-tRNA synthetase signature 106 123 1.2E-5 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THSYN_RS13670 ee82f3beb0f889101c6d9f63364a5d19 334 PRINTS PR00982 Lysyl-tRNA synthetase signature 217 233 1.2E-5 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THSYN_RS13670 ee82f3beb0f889101c6d9f63364a5d19 334 Pfam PF00152 tRNA synthetases class II (D, K and N) 218 331 2.8E-17 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS13670 ee82f3beb0f889101c6d9f63364a5d19 334 Pfam PF00152 tRNA synthetases class II (D, K and N) 22 143 1.4E-13 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS13670 ee82f3beb0f889101c6d9f63364a5d19 334 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 23 329 2.6E-113 T 29-03-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 THSYN_RS13670 ee82f3beb0f889101c6d9f63364a5d19 334 SUPERFAMILY SSF55681 22 331 1.16E-65 T 29-03-2018 THSYN_RS07310 6cdd81ffaf43691699c007769e6cbeb7 157 Pfam PF00578 AhpC/TSA family 5 133 3.3E-35 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THSYN_RS07310 6cdd81ffaf43691699c007769e6cbeb7 157 Gene3D G3DSA:3.40.30.10 1 157 9.5E-36 T 29-03-2018 THSYN_RS07310 6cdd81ffaf43691699c007769e6cbeb7 157 PIRSF PIRSF000239 1 157 1.4E-24 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THSYN_RS07310 6cdd81ffaf43691699c007769e6cbeb7 157 SUPERFAMILY SSF52833 1 154 1.72E-48 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS09725 8eee6d1a6fabd5ee1b56dd0b9fc8917e 359 SUPERFAMILY SSF50331 240 358 5.32E-19 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal THSYN_RS09725 8eee6d1a6fabd5ee1b56dd0b9fc8917e 359 Pfam PF00005 ABC transporter 28 163 1.4E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS09725 8eee6d1a6fabd5ee1b56dd0b9fc8917e 359 Pfam PF03459 TOBE domain 296 358 9.7E-14 T 29-03-2018 IPR005116 Transport-associated OB, type 1 THSYN_RS09725 8eee6d1a6fabd5ee1b56dd0b9fc8917e 359 Gene3D G3DSA:2.40.50.100 279 357 2.2E-19 T 29-03-2018 THSYN_RS09725 8eee6d1a6fabd5ee1b56dd0b9fc8917e 359 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 4 358 4.4E-127 T 29-03-2018 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 THSYN_RS09725 8eee6d1a6fabd5ee1b56dd0b9fc8917e 359 SMART SM00382 25 213 3.0E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS09725 8eee6d1a6fabd5ee1b56dd0b9fc8917e 359 SUPERFAMILY SSF52540 10 226 6.27E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09725 8eee6d1a6fabd5ee1b56dd0b9fc8917e 359 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS09725 8eee6d1a6fabd5ee1b56dd0b9fc8917e 359 Gene3D G3DSA:3.40.50.300 15 251 2.0E-54 T 29-03-2018 THSYN_RS28845 d32c17c9839139c40166b1ff89e03b6b 153 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 141 1.5E-57 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THSYN_RS28845 d32c17c9839139c40166b1ff89e03b6b 153 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 29-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THSYN_RS28845 d32c17c9839139c40166b1ff89e03b6b 153 SUPERFAMILY SSF52304 3 144 9.03E-59 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THSYN_RS28845 d32c17c9839139c40166b1ff89e03b6b 153 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 17 145 8.0E-47 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THSYN_RS28845 d32c17c9839139c40166b1ff89e03b6b 153 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 153 70.428 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THSYN_RS28845 d32c17c9839139c40166b1ff89e03b6b 153 Gene3D G3DSA:3.40.50.9100 1 146 5.6E-62 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THSYN_RS28845 d32c17c9839139c40166b1ff89e03b6b 153 Pfam PF01220 Dehydroquinase class II 3 140 1.6E-57 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THSYN_RS28845 d32c17c9839139c40166b1ff89e03b6b 153 PIRSF PIRSF001399 1 146 2.7E-55 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THSYN_RS07335 8b91c6c9dee2cd1f4b4c8c3311c5c1e6 472 Gene3D G3DSA:3.30.565.10 325 470 1.5E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07335 8b91c6c9dee2cd1f4b4c8c3311c5c1e6 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 410 2.8E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07335 8b91c6c9dee2cd1f4b4c8c3311c5c1e6 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 461 2.8E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07335 8b91c6c9dee2cd1f4b4c8c3311c5c1e6 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 443 2.8E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07335 8b91c6c9dee2cd1f4b4c8c3311c5c1e6 472 Gene3D G3DSA:1.10.287.130 227 314 5.7E-5 T 29-03-2018 THSYN_RS07335 8b91c6c9dee2cd1f4b4c8c3311c5c1e6 472 SUPERFAMILY SSF47384 251 312 1.79E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS07335 8b91c6c9dee2cd1f4b4c8c3311c5c1e6 472 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 463 2.4E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07335 8b91c6c9dee2cd1f4b4c8c3311c5c1e6 472 SUPERFAMILY SSF55874 326 464 5.63E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07335 8b91c6c9dee2cd1f4b4c8c3311c5c1e6 472 SMART SM00387 361 464 4.6E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS30140 50168c5fcdab4a03feccf9a8711c6dde 153 TIGRFAM TIGR03741 PRTRC_E: PRTRC system protein E 3 116 1.5E-10 T 29-03-2018 IPR022273 ParB-related, ThiF-related cassette, protein E THSYN_RS27055 fd1fa23a283ced8acd685dd29ff075d3 711 SMART SM00729 368 621 1.7E-9 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS27055 fd1fa23a283ced8acd685dd29ff075d3 711 Gene3D G3DSA:3.20.20.70 302 692 1.3E-33 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS27055 fd1fa23a283ced8acd685dd29ff075d3 711 Pfam PF04055 Radical SAM superfamily 372 577 1.9E-19 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS27055 fd1fa23a283ced8acd685dd29ff075d3 711 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 372 392 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 THSYN_RS27055 fd1fa23a283ced8acd685dd29ff075d3 711 Gene3D G3DSA:3.40.50.280 41 203 0.0019 T 29-03-2018 THSYN_RS27055 fd1fa23a283ced8acd685dd29ff075d3 711 Pfam PF11842 Domain of unknown function (DUF3362) 586 689 8.6E-49 T 29-03-2018 IPR024560 Uncharacterised protein family UPF0313, C-terminal THSYN_RS27055 fd1fa23a283ced8acd685dd29ff075d3 711 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 23 638 48.868 T 29-03-2018 IPR022946 Uncharacterised protein family UPF0313 THSYN_RS27055 fd1fa23a283ced8acd685dd29ff075d3 711 SUPERFAMILY SSF102114 361 432 8.63E-13 T 29-03-2018 THSYN_RS27055 fd1fa23a283ced8acd685dd29ff075d3 711 SUPERFAMILY SSF102114 462 610 8.63E-13 T 29-03-2018 THSYN_RS27055 fd1fa23a283ced8acd685dd29ff075d3 711 Pfam PF08497 Radical SAM N-terminal 24 371 1.8E-137 T 29-03-2018 IPR013704 Uncharacterised protein family UPF0313, N-terminal THSYN_RS27055 fd1fa23a283ced8acd685dd29ff075d3 711 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 24 636 1.8E-251 T 29-03-2018 IPR022946 Uncharacterised protein family UPF0313 THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 ProSitePatterns PS00018 EF-hand calcium-binding domain. 42 54 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 Gene3D G3DSA:1.10.238.10 4 49 0.0055 T 29-03-2018 THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 ProSitePatterns PS00018 EF-hand calcium-binding domain. 186 198 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 Pfam PF13202 EF hand 181 199 1.7E-4 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 Pfam PF13202 EF hand 138 157 1.8E-4 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 Gene3D G3DSA:1.10.238.10 189 212 5.0E-4 T 29-03-2018 THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 Gene3D G3DSA:1.10.238.10 50 91 3.7E-10 T 29-03-2018 THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 ProSitePatterns PS00018 EF-hand calcium-binding domain. 143 155 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 Gene3D G3DSA:1.10.238.10 92 149 1.3E-10 T 29-03-2018 THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 ProSitePatterns PS00018 EF-hand calcium-binding domain. 85 97 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 Gene3D G3DSA:1.10.238.10 150 188 2.1E-9 T 29-03-2018 THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 SUPERFAMILY SSF47473 37 106 2.54E-18 T 29-03-2018 IPR011992 EF-hand domain pair THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 SUPERFAMILY SSF47473 135 200 2.54E-18 T 29-03-2018 IPR011992 EF-hand domain pair THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 Pfam PF13499 EF-hand domain pair 38 99 2.4E-8 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 SMART SM00054 177 205 41.0 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 SMART SM00054 134 162 9.0 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 SMART SM00054 76 104 0.2 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS18915 6a0629afe44280a36e312a4aa44aee62 213 SMART SM00054 36 61 23.0 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS13355 b4912519b033e27b2694b6b83946d7e8 464 Gene3D G3DSA:3.30.70.150 13 138 4.8E-37 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS13355 b4912519b033e27b2694b6b83946d7e8 464 SUPERFAMILY SSF54966 4 139 2.88E-48 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS13355 b4912519b033e27b2694b6b83946d7e8 464 SUPERFAMILY SSF51649 140 457 1.14E-108 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS13355 b4912519b033e27b2694b6b83946d7e8 464 Hamap MF_01339 Ribulose bisphosphate carboxylase [cbbM]. 3 461 77.417 T 29-03-2018 IPR020871 Ribulose bisphosphate carboxylase large subunit, type II GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS13355 b4912519b033e27b2694b6b83946d7e8 464 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 14 132 3.2E-37 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS13355 b4912519b033e27b2694b6b83946d7e8 464 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 145 442 2.6E-112 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS13355 b4912519b033e27b2694b6b83946d7e8 464 Gene3D G3DSA:3.20.20.110 140 443 5.9E-107 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS13355 b4912519b033e27b2694b6b83946d7e8 464 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 188 196 - T 29-03-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS12435 66c5efcbff443d90dae2143a9a75c708 620 SUPERFAMILY SSF54211 405 487 4.43E-7 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS12435 66c5efcbff443d90dae2143a9a75c708 620 Gene3D G3DSA:3.30.230.40 400 491 1.0E-8 T 29-03-2018 THSYN_RS12435 66c5efcbff443d90dae2143a9a75c708 620 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 184 8.3E-22 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS12435 66c5efcbff443d90dae2143a9a75c708 620 Gene3D G3DSA:3.40.50.1000 64 222 1.1E-29 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS12435 66c5efcbff443d90dae2143a9a75c708 620 Gene3D G3DSA:3.30.230.40 290 386 1.6E-4 T 29-03-2018 THSYN_RS12435 66c5efcbff443d90dae2143a9a75c708 620 Gene3D G3DSA:3.30.230.40 504 620 0.0018 T 29-03-2018 THSYN_RS12435 66c5efcbff443d90dae2143a9a75c708 620 SUPERFAMILY SSF56784 1 210 2.47E-39 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS12435 66c5efcbff443d90dae2143a9a75c708 620 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 232 366 3.0E-5 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 THSYN_RS12435 66c5efcbff443d90dae2143a9a75c708 620 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 442 598 8.0E-7 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 THSYN_RS12435 66c5efcbff443d90dae2143a9a75c708 620 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 73 184 6.5E-14 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS24170 43eef5c573fa037af85be1d2330e9446 503 SMART SM00382 201 344 4.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS24170 43eef5c573fa037af85be1d2330e9446 503 Gene3D G3DSA:3.40.50.300 177 353 8.2E-27 T 29-03-2018 THSYN_RS24170 43eef5c573fa037af85be1d2330e9446 503 Gene3D G3DSA:3.40.50.10770 3 142 1.0E-4 T 29-03-2018 THSYN_RS24170 43eef5c573fa037af85be1d2330e9446 503 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 205 218 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THSYN_RS24170 43eef5c573fa037af85be1d2330e9446 503 Gene3D G3DSA:1.10.8.60 354 430 8.9E-19 T 29-03-2018 THSYN_RS24170 43eef5c573fa037af85be1d2330e9446 503 SUPERFAMILY SSF52540 182 429 4.0E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24170 43eef5c573fa037af85be1d2330e9446 503 Pfam PF00158 Sigma-54 interaction domain 182 347 3.9E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THSYN_RS24170 43eef5c573fa037af85be1d2330e9446 503 Pfam PF02954 Bacterial regulatory protein, Fis family 463 498 1.1E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS24170 43eef5c573fa037af85be1d2330e9446 503 Gene3D G3DSA:1.10.10.60 431 503 4.6E-13 T 29-03-2018 THSYN_RS24170 43eef5c573fa037af85be1d2330e9446 503 SUPERFAMILY SSF46689 398 501 5.73E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS27935 de878b38228c0b825a5b915010a23a61 340 Pfam PF01944 Stage II sporulation protein M 113 293 2.2E-29 T 29-03-2018 IPR002798 Stage II sporulation protein M-like THSYN_RS08760 6196d3185594565d5502fbe25b49d42a 299 Pfam PF14236 Domain of unknown function (DUF4338) 95 291 9.7E-67 T 29-03-2018 IPR025639 Domain of unknown function DUF4338 THSYN_RS02090 6196d3185594565d5502fbe25b49d42a 299 Pfam PF14236 Domain of unknown function (DUF4338) 95 291 9.7E-67 T 29-03-2018 IPR025639 Domain of unknown function DUF4338 THSYN_RS05525 6196d3185594565d5502fbe25b49d42a 299 Pfam PF14236 Domain of unknown function (DUF4338) 95 291 9.7E-67 T 29-03-2018 IPR025639 Domain of unknown function DUF4338 THSYN_RS14550 6196d3185594565d5502fbe25b49d42a 299 Pfam PF14236 Domain of unknown function (DUF4338) 95 291 9.7E-67 T 29-03-2018 IPR025639 Domain of unknown function DUF4338 THSYN_RS23630 6196d3185594565d5502fbe25b49d42a 299 Pfam PF14236 Domain of unknown function (DUF4338) 95 291 9.7E-67 T 29-03-2018 IPR025639 Domain of unknown function DUF4338 THSYN_RS07780 6196d3185594565d5502fbe25b49d42a 299 Pfam PF14236 Domain of unknown function (DUF4338) 95 291 9.7E-67 T 29-03-2018 IPR025639 Domain of unknown function DUF4338 THSYN_RS12870 a0e7c361ea3107a0aa019f13b3dd61d1 679 Gene3D G3DSA:1.10.443.10 487 672 2.8E-10 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS12870 a0e7c361ea3107a0aa019f13b3dd61d1 679 SUPERFAMILY SSF56349 493 647 1.41E-7 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS12870 a0e7c361ea3107a0aa019f13b3dd61d1 679 Gene3D G3DSA:1.20.1170.10 114 409 8.5E-7 T 29-03-2018 THSYN_RS02805 55e3c95817531d45e61ce3a98bf7791d 488 Pfam PF01593 Flavin containing amine oxidoreductase 28 476 2.2E-54 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THSYN_RS02805 55e3c95817531d45e61ce3a98bf7791d 488 Gene3D G3DSA:1.10.405.10 117 209 3.1E-10 T 29-03-2018 THSYN_RS02805 55e3c95817531d45e61ce3a98bf7791d 488 Gene3D G3DSA:3.50.50.60 6 105 9.3E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS02805 55e3c95817531d45e61ce3a98bf7791d 488 PRINTS PR00757 Flavin-containing amine oxidase signature 457 474 5.6E-5 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THSYN_RS02805 55e3c95817531d45e61ce3a98bf7791d 488 PRINTS PR00757 Flavin-containing amine oxidase signature 20 39 5.6E-5 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THSYN_RS02805 55e3c95817531d45e61ce3a98bf7791d 488 Gene3D G3DSA:3.90.660.10 210 420 7.6E-30 T 29-03-2018 THSYN_RS02805 55e3c95817531d45e61ce3a98bf7791d 488 SUPERFAMILY SSF51905 19 323 1.76E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS02805 55e3c95817531d45e61ce3a98bf7791d 488 SUPERFAMILY SSF51905 429 477 1.76E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS02805 55e3c95817531d45e61ce3a98bf7791d 488 SUPERFAMILY SSF54373 304 415 2.81E-11 T 29-03-2018 THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 SMART SM00091 403 471 4.0E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 SMART SM00091 269 341 1.8E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 524 682 2.4E-46 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 Gene3D G3DSA:3.30.450.20 236 399 4.6E-28 T 29-03-2018 THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 Gene3D G3DSA:3.30.450.20 400 523 2.7E-22 T 29-03-2018 THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 SUPERFAMILY SSF158472 193 242 7.98E-9 T 29-03-2018 THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 Gene3D G3DSA:3.30.70.270 524 683 3.0E-51 T 29-03-2018 THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 SUPERFAMILY SSF55073 532 682 1.1E-42 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 SMART SM00267 516 684 3.0E-59 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 Pfam PF13188 PAS domain 403 445 4.8E-4 T 29-03-2018 IPR000014 PAS domain THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 Pfam PF00672 HAMP domain 193 241 4.5E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 SUPERFAMILY SSF55785 254 389 1.73E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 Pfam PF08448 PAS fold 276 393 2.0E-12 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 402 523 6.0E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 266 397 1.5E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 Pfam PF00990 Diguanylate cyclase, GGDEF domain 527 680 1.2E-40 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 SUPERFAMILY SSF55785 388 504 9.6E-19 T 29-03-2018 IPR000014 PAS domain THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 SMART SM00304 193 245 1.9E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 SMART SM00086 348 391 0.013 T 29-03-2018 IPR001610 PAC motif THSYN_RS25885 8fda8e81301a1aefa24d659d5a8b7f40 685 SMART SM00086 477 516 0.022 T 29-03-2018 IPR001610 PAC motif THSYN_RS19390 b09208dd3f0b85d867d530cacb736201 252 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 8 46 5.6E-17 T 29-03-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal THSYN_RS19390 b09208dd3f0b85d867d530cacb736201 252 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 7 225 1.1E-23 T 29-03-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 THSYN_RS19390 b09208dd3f0b85d867d530cacb736201 252 TIGRFAM TIGR01876 cas_Cas5d: CRISPR-associated protein Cas5, subtype I-C/DVULG 8 246 9.2E-37 T 29-03-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 THSYN_RS19390 b09208dd3f0b85d867d530cacb736201 252 PIRSF PIRSF029950 2 251 4.6E-52 T 29-03-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 Pfam PF08206 Ribonuclease B OB domain 190 243 1.8E-5 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 Pfam PF08206 Ribonuclease B OB domain 118 174 1.1E-21 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 TIGRFAM TIGR02063 RNase_R: ribonuclease R 50 747 1.4E-266 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 SMART SM00316 665 748 1.8E-12 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 SMART SM00316 111 173 58.0 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 Gene3D G3DSA:2.40.50.140 664 749 5.0E-19 T 29-03-2018 THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 SUPERFAMILY SSF50249 251 664 3.31E-147 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 Hamap MF_01895 Ribonuclease R [rnr]. 69 748 58.754 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 SUPERFAMILY SSF50249 667 747 2.5E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 ProSitePatterns PS01175 Ribonuclease II family signature. 586 610 - T 29-03-2018 IPR022966 Ribonuclease II/R, conserved site THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 99 746 5.5E-234 T 29-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 SMART SM00357 117 176 5.5E-17 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 SMART SM00357 181 245 1.6 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 Pfam PF00575 S1 RNA binding domain 665 745 2.3E-12 T 29-03-2018 IPR003029 S1 domain GO:0003676 THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 SMART SM00955 291 619 1.8E-183 T 29-03-2018 THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 SUPERFAMILY SSF50249 169 267 7.89E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 SUPERFAMILY SSF50249 98 178 1.09E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 Gene3D G3DSA:2.40.50.140 112 182 1.2E-4 T 29-03-2018 THSYN_RS03725 774e2b02f5fab13a678566d94aa57e7b 768 Pfam PF00773 RNB domain 291 618 2.5E-110 T 29-03-2018 THSYN_RS31955 1c6c0bdb0a4823b56cd9585a1ff8c100 201 Gene3D G3DSA:3.90.550.10 6 199 1.6E-34 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS31955 1c6c0bdb0a4823b56cd9585a1ff8c100 201 SUPERFAMILY SSF53448 11 192 1.89E-34 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS31955 1c6c0bdb0a4823b56cd9585a1ff8c100 201 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 11 192 4.1E-68 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 THSYN_RS31955 1c6c0bdb0a4823b56cd9585a1ff8c100 201 Pfam PF12804 MobA-like NTP transferase domain 13 169 1.4E-36 T 29-03-2018 IPR025877 MobA-like NTP transferase THSYN_RS31955 1c6c0bdb0a4823b56cd9585a1ff8c100 201 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 9 196 28.358 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 THSYN_RS21980 f667ce3f4359aa42f0e3e75a7a8e4a9d 256 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 174 255 6.8E-27 T 29-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 THSYN_RS21980 f667ce3f4359aa42f0e3e75a7a8e4a9d 256 Gene3D G3DSA:1.20.1180.10 191 256 1.2E-20 T 29-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 THSYN_RS21980 f667ce3f4359aa42f0e3e75a7a8e4a9d 256 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 20 46 1.4E-7 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS21980 f667ce3f4359aa42f0e3e75a7a8e4a9d 256 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 131 2.6E-5 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS21980 f667ce3f4359aa42f0e3e75a7a8e4a9d 256 PIRSF PIRSF000456 1 256 3.4E-101 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 THSYN_RS21980 f667ce3f4359aa42f0e3e75a7a8e4a9d 256 Gene3D G3DSA:2.160.10.10 1 190 2.1E-46 T 29-03-2018 THSYN_RS21980 f667ce3f4359aa42f0e3e75a7a8e4a9d 256 SUPERFAMILY SSF51161 2 256 9.12E-79 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS21980 f667ce3f4359aa42f0e3e75a7a8e4a9d 256 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 2 255 3.6E-102 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 THSYN_RS21980 f667ce3f4359aa42f0e3e75a7a8e4a9d 256 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 256 44.243 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 THSYN_RS10930 0c8e892a7bfde1777257603885cae5a4 82 Gene3D G3DSA:3.40.1620.10 1 79 1.5E-16 T 29-03-2018 THSYN_RS10930 0c8e892a7bfde1777257603885cae5a4 82 SUPERFAMILY SSF143120 1 44 1.83E-10 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS10930 0c8e892a7bfde1777257603885cae5a4 82 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 42 9.6E-9 T 29-03-2018 THSYN_RS10930 0c8e892a7bfde1777257603885cae5a4 82 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 45 1.8E-10 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS09005 51e9ac38f6526aa78d50f0decc9134d7 494 Pfam PF03441 FAD binding domain of DNA photolyase 288 488 1.2E-85 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 THSYN_RS09005 51e9ac38f6526aa78d50f0decc9134d7 494 Gene3D G3DSA:1.10.579.10 308 493 1.4E-77 T 29-03-2018 THSYN_RS09005 51e9ac38f6526aa78d50f0decc9134d7 494 Gene3D G3DSA:1.25.40.80 130 307 5.4E-39 T 29-03-2018 THSYN_RS09005 51e9ac38f6526aa78d50f0decc9134d7 494 Pfam PF00875 DNA photolyase 5 172 1.4E-47 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 THSYN_RS09005 51e9ac38f6526aa78d50f0decc9134d7 494 PRINTS PR00147 DNA photolyase signature 141 157 1.7E-20 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 THSYN_RS09005 51e9ac38f6526aa78d50f0decc9134d7 494 PRINTS PR00147 DNA photolyase signature 359 377 1.7E-20 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 THSYN_RS09005 51e9ac38f6526aa78d50f0decc9134d7 494 PRINTS PR00147 DNA photolyase signature 398 412 1.7E-20 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 THSYN_RS09005 51e9ac38f6526aa78d50f0decc9134d7 494 PRINTS PR00147 DNA photolyase signature 339 355 1.7E-20 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 THSYN_RS09005 51e9ac38f6526aa78d50f0decc9134d7 494 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 339 351 - T 29-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal THSYN_RS09005 51e9ac38f6526aa78d50f0decc9134d7 494 SUPERFAMILY SSF48173 197 492 1.83E-106 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 THSYN_RS09005 51e9ac38f6526aa78d50f0decc9134d7 494 Gene3D G3DSA:3.40.50.620 2 129 2.1E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS09005 51e9ac38f6526aa78d50f0decc9134d7 494 SUPERFAMILY SSF52425 4 212 1.23E-52 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 Pfam PF00873 AcrB/AcrD/AcrF family 5 1002 3.2E-233 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 SUPERFAMILY SSF82866 291 489 4.19E-45 T 29-03-2018 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 SUPERFAMILY SSF82714 695 782 6.41E-10 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 Gene3D G3DSA:3.30.2090.10 180 267 3.6E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 SUPERFAMILY SSF82714 182 264 5.23E-10 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 SUPERFAMILY SSF82866 783 1003 8.63E-44 T 29-03-2018 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 Gene3D G3DSA:3.30.2090.10 694 784 4.9E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 Gene3D G3DSA:3.30.70.1430 40 141 3.0E-24 T 29-03-2018 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 SUPERFAMILY SSF82693 40 132 8.02E-22 T 29-03-2018 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 Gene3D G3DSA:1.20.1640.10 796 1005 4.6E-36 T 29-03-2018 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 SUPERFAMILY SSF82693 267 312 3.56E-11 T 29-03-2018 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 SUPERFAMILY SSF82693 137 181 3.56E-11 T 29-03-2018 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 SUPERFAMILY SSF82693 545 644 9.68E-10 T 29-03-2018 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 2.0E-55 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 2.0E-55 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 2.0E-55 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.0E-55 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 2.0E-55 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 PRINTS PR00702 Acriflavin resistance protein family signature 531 548 2.0E-55 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.0E-55 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 2.0E-55 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 Gene3D G3DSA:3.30.70.1430 546 650 1.9E-16 T 29-03-2018 THSYN_RS17145 4f2fdcf644ec729578a014e29622a66b 1049 Gene3D G3DSA:1.20.1640.10 279 498 4.3E-40 T 29-03-2018 THSYN_RS01060 71b21c78e89d6913e364ce8589855581 213 PIRSF PIRSF000370 1 213 2.9E-32 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 THSYN_RS01060 71b21c78e89d6913e364ce8589855581 213 SUPERFAMILY SSF102114 46 138 1.96E-7 T 29-03-2018 THSYN_RS01060 71b21c78e89d6913e364ce8589855581 213 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 213 33.377 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 THSYN_RS01060 71b21c78e89d6913e364ce8589855581 213 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 3 213 9.4E-105 T 29-03-2018 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 THSYN_RS01060 71b21c78e89d6913e364ce8589855581 213 Gene3D G3DSA:3.20.20.70 25 208 4.8E-13 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS01060 71b21c78e89d6913e364ce8589855581 213 Pfam PF04055 Radical SAM superfamily 46 180 3.7E-7 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS13445 bff2f89860c61ac9862b09bc96032ecc 75 SUPERFAMILY SSF46689 1 63 1.68E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS13445 bff2f89860c61ac9862b09bc96032ecc 75 Gene3D G3DSA:1.10.10.10 7 66 5.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS13445 bff2f89860c61ac9862b09bc96032ecc 75 Pfam PF04255 Protein of unknown function (DUF433) 7 62 5.0E-23 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 254 263 2.8E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 266 289 2.8E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 133 144 2.8E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 2.8E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 146 3.1E-49 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 5 302 79.538 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 Gene3D G3DSA:3.40.50.1370 163 302 1.1E-45 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 153 299 3.4E-46 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 6 301 4.7E-115 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 122 136 1.6E-28 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 49 63 1.6E-28 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 82 95 1.6E-28 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 218 228 1.6E-28 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 280 291 1.6E-28 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 Gene3D G3DSA:3.40.50.1370 4 162 7.7E-62 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THSYN_RS06170 b2a54ef117d137bd9999a7fc4968e25a 305 SUPERFAMILY SSF53671 3 301 1.13E-101 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 138 266 4.9E-29 T 29-03-2018 IPR000014 PAS domain THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 Gene3D G3DSA:3.40.50.2300 549 679 3.9E-40 T 29-03-2018 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 Pfam PF00512 His Kinase A (phospho-acceptor) domain 297 361 1.9E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 Pfam PF01627 Hpt domain 725 801 6.4E-11 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 SUPERFAMILY SSF52172 4 153 1.25E-25 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 SMART SM00091 142 208 2.6E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 Gene3D G3DSA:1.20.120.160 703 814 5.8E-14 T 29-03-2018 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 Pfam PF00989 PAS fold 147 256 1.2E-17 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 SUPERFAMILY SSF47226 652 665 4.32E-18 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 SUPERFAMILY SSF47226 704 802 4.32E-18 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 Pfam PF00072 Response regulator receiver domain 7 117 6.6E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 Pfam PF00072 Response regulator receiver domain 559 668 2.9E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 SUPERFAMILY SSF55874 351 518 1.57E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 SUPERFAMILY SSF52172 552 674 3.7E-39 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 Gene3D G3DSA:3.30.450.20 129 287 4.1E-30 T 29-03-2018 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 464 2.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 478 2.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 503 2.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 522 2.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 SMART SM00388 297 362 4.0E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 SMART SM00387 409 525 1.2E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 SUPERFAMILY SSF47384 283 363 6.67E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 Gene3D G3DSA:1.10.287.130 288 358 7.6E-17 T 29-03-2018 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 SUPERFAMILY SSF55785 130 256 4.01E-28 T 29-03-2018 IPR000014 PAS domain THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 409 524 9.9E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 Gene3D G3DSA:3.30.565.10 366 532 4.8E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 Gene3D G3DSA:3.40.50.2300 1 128 2.8E-26 T 29-03-2018 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 SMART SM00448 556 669 8.1E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS29465 a67c22631121fe8f660184515a15ae3a 834 SMART SM00448 5 117 3.1E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS03095 11d21f9b6f3c5012b7b8842887ab3818 135 Gene3D G3DSA:3.40.50.1010 1 135 5.9E-27 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS03095 11d21f9b6f3c5012b7b8842887ab3818 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 132 10.84 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS03095 11d21f9b6f3c5012b7b8842887ab3818 135 Pfam PF01850 PIN domain 3 126 1.9E-12 T 29-03-2018 IPR002716 PIN domain THSYN_RS03095 11d21f9b6f3c5012b7b8842887ab3818 135 SUPERFAMILY SSF88723 2 133 5.61E-32 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS05740 6b66ec2d2c2b2554744b01ef27ecdd4d 110 SMART SM00530 15 74 2.4E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS05740 6b66ec2d2c2b2554744b01ef27ecdd4d 110 Gene3D G3DSA:1.10.260.40 3 80 2.4E-18 T 29-03-2018 THSYN_RS05740 6b66ec2d2c2b2554744b01ef27ecdd4d 110 SUPERFAMILY SSF47413 11 80 1.3E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS05740 6b66ec2d2c2b2554744b01ef27ecdd4d 110 Pfam PF13560 Helix-turn-helix domain 12 71 1.2E-14 T 29-03-2018 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Pfam PF04560 RNA polymerase Rpb2, domain 7 1314 1388 3.9E-26 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1390 12.391 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1387 0.0 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Gene3D G3DSA:2.40.270.10 1088 1290 1.9E-78 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1108 1120 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Pfam PF10385 RNA polymerase beta subunit external 1 domain 619 684 6.7E-22 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Pfam PF04563 RNA polymerase beta subunit 27 527 3.2E-40 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Pfam PF04561 RNA polymerase Rpb2, domain 2 449 482 3.1E-5 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Pfam PF04561 RNA polymerase Rpb2, domain 2 158 230 7.1E-7 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Gene3D G3DSA:2.40.50.100 743 823 1.7E-27 T 29-03-2018 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Gene3D G3DSA:3.90.1800.10 1315 1357 6.4E-11 T 29-03-2018 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Pfam PF04565 RNA polymerase Rpb2, domain 3 541 608 1.9E-30 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Pfam PF00562 RNA polymerase Rpb2, domain 6 746 1312 1.5E-160 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Gene3D G3DSA:3.90.1100.10 672 741 9.8E-17 T 29-03-2018 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Gene3D G3DSA:3.90.1100.10 461 671 3.9E-77 T 29-03-2018 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Gene3D G3DSA:2.40.50.150 857 1087 1.8E-54 T 29-03-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 Gene3D G3DSA:3.90.1110.10 154 460 1.4E-64 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 SUPERFAMILY SSF64484 12 232 0.0 T 29-03-2018 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 SUPERFAMILY SSF64484 349 417 0.0 T 29-03-2018 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 SUPERFAMILY SSF64484 1084 1389 0.0 T 29-03-2018 THSYN_RS05720 1d955d050f97b58cc741aadcd91459de 1390 SUPERFAMILY SSF64484 450 967 0.0 T 29-03-2018 THSYN_RS05375 665d39018f59f5e589a1bccbd01c254a 188 SUPERFAMILY SSF55811 43 185 5.01E-23 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 THSYN_RS05375 665d39018f59f5e589a1bccbd01c254a 188 ProSitePatterns PS00893 Nudix box signature. 82 103 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THSYN_RS05375 665d39018f59f5e589a1bccbd01c254a 188 PRINTS PR01404 DATP pyrophosphohydrolase signature 112 131 7.5E-9 T 29-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 THSYN_RS05375 665d39018f59f5e589a1bccbd01c254a 188 PRINTS PR01404 DATP pyrophosphohydrolase signature 48 65 7.5E-9 T 29-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 THSYN_RS05375 665d39018f59f5e589a1bccbd01c254a 188 PRINTS PR01404 DATP pyrophosphohydrolase signature 169 182 7.5E-9 T 29-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 THSYN_RS05375 665d39018f59f5e589a1bccbd01c254a 188 Pfam PF00293 NUDIX domain 50 165 3.0E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THSYN_RS05375 665d39018f59f5e589a1bccbd01c254a 188 Gene3D G3DSA:3.90.79.10 43 186 1.5E-21 T 29-03-2018 THSYN_RS15220 e138c33ba22e3e8ebdc678754104964a 938 Pfam PF12698 ABC-2 family transporter protein 592 930 1.7E-33 T 29-03-2018 THSYN_RS15220 e138c33ba22e3e8ebdc678754104964a 938 Pfam PF00005 ABC transporter 308 451 1.1E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS15220 e138c33ba22e3e8ebdc678754104964a 938 Pfam PF00005 ABC transporter 44 191 6.5E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS15220 e138c33ba22e3e8ebdc678754104964a 938 SMART SM00382 316 507 8.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS15220 e138c33ba22e3e8ebdc678754104964a 938 SMART SM00382 53 270 2.0E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS15220 e138c33ba22e3e8ebdc678754104964a 938 SUPERFAMILY SSF52540 282 514 1.13E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15220 e138c33ba22e3e8ebdc678754104964a 938 Gene3D G3DSA:3.40.1710.10 604 757 6.2E-21 T 29-03-2018 THSYN_RS15220 e138c33ba22e3e8ebdc678754104964a 938 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS15220 e138c33ba22e3e8ebdc678754104964a 938 Gene3D G3DSA:3.40.50.300 26 278 1.2E-56 T 29-03-2018 THSYN_RS15220 e138c33ba22e3e8ebdc678754104964a 938 Gene3D G3DSA:3.40.50.300 289 529 6.1E-63 T 29-03-2018 THSYN_RS15220 e138c33ba22e3e8ebdc678754104964a 938 SUPERFAMILY SSF52540 31 255 6.12E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10875 4cb9b300facb4c0fc8e3f80aa32c9b48 379 Gene3D G3DSA:2.40.10.10 3 132 3.2E-4 T 29-03-2018 THSYN_RS10875 4cb9b300facb4c0fc8e3f80aa32c9b48 379 Pfam PF13365 Trypsin-like peptidase domain 22 148 1.5E-6 T 29-03-2018 THSYN_RS10875 4cb9b300facb4c0fc8e3f80aa32c9b48 379 Gene3D G3DSA:2.60.40.1120 269 349 2.2E-7 T 29-03-2018 THSYN_RS10875 4cb9b300facb4c0fc8e3f80aa32c9b48 379 SUPERFAMILY SSF49464 275 342 8.11E-9 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain THSYN_RS10875 4cb9b300facb4c0fc8e3f80aa32c9b48 379 Pfam PF13620 Carboxypeptidase regulatory-like domain 275 336 1.3E-7 T 29-03-2018 THSYN_RS10875 4cb9b300facb4c0fc8e3f80aa32c9b48 379 SUPERFAMILY SSF50494 4 139 5.95E-10 T 29-03-2018 IPR009003 Peptidase S1, PA clan THSYN_RS09605 e40ced1286dab038576ff2d70796b401 243 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 42 59 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09605 e40ced1286dab038576ff2d70796b401 243 Gene3D G3DSA:3.10.20.30 9 121 2.9E-12 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS09605 e40ced1286dab038576ff2d70796b401 243 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 201 212 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS09605 e40ced1286dab038576ff2d70796b401 243 SMART SM00929 94 134 4.9E-14 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09605 e40ced1286dab038576ff2d70796b401 243 Gene3D G3DSA:3.30.70.20 163 208 3.1E-12 T 29-03-2018 THSYN_RS09605 e40ced1286dab038576ff2d70796b401 243 PIRSF PIRSF000309 10 243 1.1E-101 T 29-03-2018 IPR016214 NAD-reducing hydrogenase, HoxS gamma subunit MetaCyc: PWY-5382|MetaCyc: PWY-6758 THSYN_RS09605 e40ced1286dab038576ff2d70796b401 243 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 94 133 4.9E-14 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09605 e40ced1286dab038576ff2d70796b401 243 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 11 87 5.1E-18 T 29-03-2018 THSYN_RS09605 e40ced1286dab038576ff2d70796b401 243 SUPERFAMILY SSF54862 86 217 3.52E-34 T 29-03-2018 THSYN_RS09605 e40ced1286dab038576ff2d70796b401 243 Pfam PF00037 4Fe-4S binding domain 199 216 9.4E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS09605 e40ced1286dab038576ff2d70796b401 243 Gene3D G3DSA:3.30.70.20 209 241 5.3E-6 T 29-03-2018 THSYN_RS09605 e40ced1286dab038576ff2d70796b401 243 SUPERFAMILY SSF54292 13 84 2.06E-17 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS09605 e40ced1286dab038576ff2d70796b401 243 Gene3D G3DSA:3.30.70.20 122 162 0.0038 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 SUPERFAMILY SSF51126 1338 1417 2.16E-25 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 SUPERFAMILY SSF51126 1445 1697 2.16E-25 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 SUPERFAMILY SSF50985 377 592 4.71E-49 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 SUPERFAMILY SSF50985 895 1138 6.37E-34 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 SUPERFAMILY SSF103647 721 814 1.44E-17 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 SUPERFAMILY SSF103647 1227 1283 2.48E-9 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:2.130.10.30 369 487 3.2E-26 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:2.130.10.30 1056 1143 4.6E-12 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 SUPERFAMILY SSF103647 1284 1337 3.01E-13 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF05345 Putative Ig domain 1179 1212 3.2E-8 T 29-03-2018 IPR008009 Putative Ig THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:2.130.10.30 892 1055 3.3E-24 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 SUPERFAMILY SSF50985 191 406 9.59E-44 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:2.130.10.30 520 630 1.6E-16 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 120 146 2.5E-6 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 341 366 3.3E-5 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 966 993 6.3E-7 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 194 221 2.2E-7 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 231 258 4.3E-8 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 156 183 1.8E-7 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 491 518 2.7E-8 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 528 556 6.3E-5 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 415 443 5.1E-9 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 455 482 1.0E-7 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 1076 1102 1.4E-5 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 268 292 2.5E-6 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 929 956 6.6E-7 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 1003 1030 1.2E-8 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 304 332 1.6E-11 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:4.10.510.10 226 260 1.4E-5 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:4.10.510.10 115 147 2.0E-8 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:4.10.510.10 301 334 5.8E-10 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:4.10.510.10 190 224 2.0E-7 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:4.10.510.10 153 185 3.6E-7 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:4.10.510.10 488 519 1.1E-6 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:4.10.510.10 337 368 1.1E-4 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:4.10.510.10 263 295 4.0E-6 T 29-03-2018 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:4.10.1080.10 1214 1291 1.7E-10 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:4.10.1080.10 689 793 1.2E-18 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:4.10.1080.10 794 889 8.9E-16 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Gene3D G3DSA:2.160.20.10 1336 1699 5.7E-24 T 29-03-2018 IPR012334 Pectin lyase fold THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 SUPERFAMILY SSF103647 814 885 3.4E-10 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 SUPERFAMILY SSF51120 1706 1787 4.19E-11 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 SUPERFAMILY SSF51120 1634 1655 4.19E-11 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF02412 Thrombospondin type 3 repeat 1257 1285 8.5E-4 T 29-03-2018 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF02412 Thrombospondin type 3 repeat 1289 1324 1.3E-7 T 29-03-2018 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF02412 Thrombospondin type 3 repeat 748 777 8.1E-5 T 29-03-2018 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF02412 Thrombospondin type 3 repeat 723 746 8.3E-4 T 29-03-2018 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 THSYN_RS05350 07e18519c5126f51b05f98da4440891c 1841 Pfam PF02412 Thrombospondin type 3 repeat 1232 1253 8.5E-4 T 29-03-2018 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 THSYN_RS20280 63bbf36789e9dff2dd23bac39cab4212 126 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 43 6.2E-7 T 29-03-2018 THSYN_RS20280 63bbf36789e9dff2dd23bac39cab4212 126 Pfam PF03683 Uncharacterised protein family (UPF0175) 38 104 3.6E-14 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS20280 63bbf36789e9dff2dd23bac39cab4212 126 SUPERFAMILY SSF143120 1 43 8.5E-8 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS20280 63bbf36789e9dff2dd23bac39cab4212 126 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 43 1.3E-7 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS20280 63bbf36789e9dff2dd23bac39cab4212 126 Gene3D G3DSA:3.40.1620.10 1 106 2.7E-11 T 29-03-2018 THSYN_RS03565 c7bf3d149c209e4d19d04f5ce0696ce4 292 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 193 288 1.4E-29 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03565 c7bf3d149c209e4d19d04f5ce0696ce4 292 Gene3D G3DSA:3.30.43.10 1 75 3.5E-24 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THSYN_RS03565 c7bf3d149c209e4d19d04f5ce0696ce4 292 Gene3D G3DSA:3.90.78.10 199 289 3.3E-29 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03565 c7bf3d149c209e4d19d04f5ce0696ce4 292 SUPERFAMILY SSF56176 13 200 4.0E-36 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THSYN_RS03565 c7bf3d149c209e4d19d04f5ce0696ce4 292 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 292 85.519 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03565 c7bf3d149c209e4d19d04f5ce0696ce4 292 SUPERFAMILY SSF56194 187 288 9.16E-36 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03565 c7bf3d149c209e4d19d04f5ce0696ce4 292 Gene3D G3DSA:3.30.465.10 78 198 1.5E-29 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THSYN_RS03565 c7bf3d149c209e4d19d04f5ce0696ce4 292 Pfam PF01565 FAD binding domain 28 154 8.0E-16 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THSYN_RS03565 c7bf3d149c209e4d19d04f5ce0696ce4 292 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 14 285 8.9E-58 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS19370 32516428380ae70f67fa59b55b92645d 356 PIRSF PIRSF029693 9 356 8.5E-133 T 29-03-2018 IPR016936 Uncharacterised conserved protein UCP029693 THSYN_RS19370 32516428380ae70f67fa59b55b92645d 356 Pfam PF10095 Uncharacterized protein conserved in bacteria (DUF2333) 27 356 2.7E-163 T 29-03-2018 IPR016936 Uncharacterised conserved protein UCP029693 THSYN_RS25425 1ee7d6748256db555944f5bac3572ddb 389 Pfam PF00953 Glycosyl transferase family 4 77 238 7.4E-32 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 THSYN_RS25425 1ee7d6748256db555944f5bac3572ddb 389 ProSitePatterns PS01348 MraY family signature 2. 152 163 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 547 558 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 Pfam PF13187 4Fe-4S dicluster domain 547 591 4.3E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 SUPERFAMILY SSF54862 539 595 2.55E-18 T 29-03-2018 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 Gene3D G3DSA:3.30.70.20 582 656 4.9E-6 T 29-03-2018 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 Gene3D G3DSA:3.50.50.60 140 310 3.2E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 161 2.9E-6 T 29-03-2018 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 404 420 2.9E-6 T 29-03-2018 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 141 417 4.5E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 621 746 1.6E-37 T 29-03-2018 IPR003813 Methyl-viologen-reducing hydrogenase, delta subunit GO:0015948|GO:0055114 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 Gene3D G3DSA:3.30.70.20 555 581 8.4E-13 T 29-03-2018 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 163 1.7E-7 T 29-03-2018 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 419 1.7E-7 T 29-03-2018 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 Gene3D G3DSA:3.50.50.60 321 526 3.9E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 577 588 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 SUPERFAMILY SSF51905 457 519 4.34E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 SUPERFAMILY SSF51905 140 422 4.34E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS16545 39b5d0af1e944bb436624f3b29a12700 754 Gene3D G3DSA:3.30.70.20 527 554 5.9E-5 T 29-03-2018 THSYN_RS22995 51972b61387bbe702a56472e7fb0d674 336 SUPERFAMILY SSF56349 72 326 1.0E-41 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS22995 51972b61387bbe702a56472e7fb0d674 336 Pfam PF00589 Phage integrase family 172 322 5.5E-21 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS22995 51972b61387bbe702a56472e7fb0d674 336 Gene3D G3DSA:1.10.150.130 54 162 4.9E-12 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS22995 51972b61387bbe702a56472e7fb0d674 336 Gene3D G3DSA:1.10.443.10 163 336 3.0E-30 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS15460 9c6a60014841574fc247ebb77cd284bd 364 SUPERFAMILY SSF69279 67 190 7.48E-16 T 29-03-2018 THSYN_RS15460 9c6a60014841574fc247ebb77cd284bd 364 Pfam PF05954 Phage late control gene D protein (GPD) 71 339 2.8E-14 T 29-03-2018 THSYN_RS15460 9c6a60014841574fc247ebb77cd284bd 364 Gene3D G3DSA:3.55.50.10 114 208 2.7E-4 T 29-03-2018 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 1 758 23.982 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 Gene3D G3DSA:3.10.20.310 332 369 0.057 T 29-03-2018 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 Gene3D G3DSA:3.10.20.310 74 155 3.3E-15 T 29-03-2018 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 PIRSF PIRSF006076 1 758 6.4E-245 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 Gene3D G3DSA:3.10.20.310 2 73 1.7E-8 T 29-03-2018 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 Gene3D G3DSA:3.10.20.310 156 246 6.3E-19 T 29-03-2018 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 Pfam PF01103 Surface antigen 430 758 1.7E-68 T 29-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 Gene3D G3DSA:2.40.160.50 370 758 5.0E-81 T 29-03-2018 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 6 758 1.3E-254 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 Gene3D G3DSA:3.10.20.310 248 328 4.1E-14 T 29-03-2018 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 Pfam PF07244 Surface antigen variable number repeat 248 326 8.4E-10 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 Pfam PF07244 Surface antigen variable number repeat 158 245 1.3E-15 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 Pfam PF07244 Surface antigen variable number repeat 75 154 1.2E-13 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THSYN_RS22000 e543de71844ac9bc8b2b4fa7d5bf32ca 758 Pfam PF07244 Surface antigen variable number repeat 329 403 2.5E-14 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THSYN_RS19295 bd4a235a42cf51452a28675bc45df79f 217 PIRSF PIRSF000239 8 217 1.3E-75 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THSYN_RS19295 bd4a235a42cf51452a28675bc45df79f 217 Gene3D G3DSA:3.30.1020.10 162 217 1.2E-24 T 29-03-2018 THSYN_RS19295 bd4a235a42cf51452a28675bc45df79f 217 Gene3D G3DSA:3.40.30.10 2 161 2.3E-37 T 29-03-2018 THSYN_RS19295 bd4a235a42cf51452a28675bc45df79f 217 Pfam PF00578 AhpC/TSA family 15 143 3.1E-34 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THSYN_RS19295 bd4a235a42cf51452a28675bc45df79f 217 SUPERFAMILY SSF52833 11 216 3.36E-69 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS19295 bd4a235a42cf51452a28675bc45df79f 217 Hamap MF_00401 Peroxiredoxin. 12 217 45.134 T 29-03-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THSYN_RS19295 bd4a235a42cf51452a28675bc45df79f 217 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 164 200 3.6E-14 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Gene3D G3DSA:2.60.40.1120 24 115 2.0E-8 T 29-03-2018 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 SUPERFAMILY SSF49265 967 1140 2.26E-12 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Gene3D G3DSA:2.40.50.140 479 499 0.12 T 29-03-2018 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Gene3D G3DSA:2.60.40.1120 396 478 0.0028 T 29-03-2018 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 SUPERFAMILY SSF49452 297 357 9.81E-7 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Pfam PF13620 Carboxypeptidase regulatory-like domain 24 106 9.4E-8 T 29-03-2018 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Pfam PF13620 Carboxypeptidase regulatory-like domain 495 550 6.4E-9 T 29-03-2018 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Pfam PF13620 Carboxypeptidase regulatory-like domain 303 359 2.6E-8 T 29-03-2018 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 SMART SM00060 869 945 0.0035 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 SMART SM00060 779 850 0.06 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 SMART SM00060 1061 1137 1.5E-4 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 SMART SM00060 965 1043 30.0 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 SMART SM00060 689 761 0.0048 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Gene3D G3DSA:2.60.40.1120 207 301 8.2E-4 T 29-03-2018 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Gene3D G3DSA:2.60.40.1120 116 199 7.1E-6 T 29-03-2018 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 SUPERFAMILY SSF49265 693 862 1.72E-12 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Gene3D G3DSA:2.60.40.10 773 861 2.4E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 SUPERFAMILY SSF49265 874 983 1.93E-6 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 SUPERFAMILY SSF49452 107 167 2.16E-5 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Gene3D G3DSA:2.60.40.10 1053 1142 2.9E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 SUPERFAMILY SSF49452 489 549 5.49E-7 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Gene3D G3DSA:2.60.40.10 684 772 5.7E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Gene3D G3DSA:2.60.40.10 972 1052 0.0013 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Gene3D G3DSA:2.60.40.10 867 971 6.0E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Gene3D G3DSA:2.60.40.10 588 668 0.013 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Gene3D G3DSA:2.60.40.10 500 557 9.5E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 Gene3D G3DSA:2.60.40.10 302 366 6.2E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS19500 b02e5a035da263f5ea53c38d36bbffdf 1142 SUPERFAMILY SSF49478 24 89 1.53E-5 T 29-03-2018 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 Pfam PF00009 Elongation factor Tu GTP binding domain 9 286 2.2E-56 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 SUPERFAMILY SSF54980 412 487 7.91E-18 T 29-03-2018 IPR035647 EF-G domain III/V-like THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 Gene3D G3DSA:3.30.70.240 623 693 3.1E-21 T 29-03-2018 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 SUPERFAMILY SSF54211 485 613 1.14E-11 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 Pfam PF14492 Elongation Factor G, domain II 413 483 2.9E-24 T 29-03-2018 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 SMART SM00838 614 692 2.3E-19 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 Pfam PF03764 Elongation factor G, domain IV 485 612 2.0E-8 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 Pfam PF00679 Elongation factor G C-terminus 615 691 2.7E-20 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 SUPERFAMILY SSF52540 7 286 2.51E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.6E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.6E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.6E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.6E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.6E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 SMART SM00889 486 612 1.1E-5 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 SUPERFAMILY SSF50447 255 280 8.7E-21 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 SUPERFAMILY SSF50447 309 407 8.7E-21 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 160 8.0E-25 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 Gene3D G3DSA:3.30.70.870 405 499 1.7E-23 T 29-03-2018 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 Gene3D G3DSA:3.30.230.10 500 622 1.6E-23 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 Gene3D G3DSA:2.40.30.10 280 401 2.5E-16 T 29-03-2018 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 Gene3D G3DSA:3.40.50.300 1 279 3.3E-47 T 29-03-2018 THSYN_RS27960 1350c84f52d51f97257b85af17500197 693 SUPERFAMILY SSF54980 615 691 7.19E-18 T 29-03-2018 IPR035647 EF-G domain III/V-like THSYN_RS20075 e2a2f8cf0492519a806b08d359300bb7 329 SUPERFAMILY SSF53474 29 308 3.82E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS20075 e2a2f8cf0492519a806b08d359300bb7 329 PIRSF PIRSF005211 1 328 6.7E-87 T 29-03-2018 IPR012020 AB hydrolase 4 family THSYN_RS20075 e2a2f8cf0492519a806b08d359300bb7 329 ProSitePatterns PS01133 Uncharacterized protein family UPF0017 signature. 229 270 - T 29-03-2018 IPR000952 AB hydrolase 4, conserved site THSYN_RS20075 e2a2f8cf0492519a806b08d359300bb7 329 Gene3D G3DSA:3.40.50.1820 44 327 1.7E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS20075 e2a2f8cf0492519a806b08d359300bb7 329 Pfam PF12146 Serine aminopeptidase, S33 61 273 2.3E-7 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 THSYN_RS09660 d82286ce09e3a85abf74216dc0dfbf07 45 Gene3D G3DSA:3.10.350.10 1 45 5.4E-11 T 29-03-2018 THSYN_RS09660 d82286ce09e3a85abf74216dc0dfbf07 45 SMART SM00257 1 44 2.1E-6 T 29-03-2018 IPR018392 LysM domain THSYN_RS09660 d82286ce09e3a85abf74216dc0dfbf07 45 Pfam PF01476 LysM domain 1 43 1.1E-9 T 29-03-2018 IPR018392 LysM domain THSYN_RS09660 d82286ce09e3a85abf74216dc0dfbf07 45 SUPERFAMILY SSF54106 1 43 8.37E-9 T 29-03-2018 IPR018392 LysM domain THSYN_RS00950 2986a5ce42ae606dce35008136e1621b 547 Gene3D G3DSA:3.40.50.300 388 523 1.1E-17 T 29-03-2018 THSYN_RS00950 2986a5ce42ae606dce35008136e1621b 547 Gene3D G3DSA:3.40.50.300 124 339 2.6E-21 T 29-03-2018 THSYN_RS00950 2986a5ce42ae606dce35008136e1621b 547 Pfam PF04851 Type III restriction enzyme, res subunit 143 312 1.6E-19 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS00950 2986a5ce42ae606dce35008136e1621b 547 SMART SM00490 427 510 0.0023 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS00950 2986a5ce42ae606dce35008136e1621b 547 SMART SM00487 141 351 1.2E-10 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS00950 2986a5ce42ae606dce35008136e1621b 547 Pfam PF00271 Helicase conserved C-terminal domain 408 509 9.0E-9 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS00950 2986a5ce42ae606dce35008136e1621b 547 SUPERFAMILY SSF52540 380 511 7.63E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00950 2986a5ce42ae606dce35008136e1621b 547 SUPERFAMILY SSF52540 157 314 7.63E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14790 557e49bf774a06f1182337829e8eacb2 458 SUPERFAMILY SSF47384 222 301 4.51E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS14790 557e49bf774a06f1182337829e8eacb2 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 426 4.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14790 557e49bf774a06f1182337829e8eacb2 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 4.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14790 557e49bf774a06f1182337829e8eacb2 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 445 4.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14790 557e49bf774a06f1182337829e8eacb2 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 406 4.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14790 557e49bf774a06f1182337829e8eacb2 458 Gene3D G3DSA:3.30.565.10 308 456 3.0E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14790 557e49bf774a06f1182337829e8eacb2 458 Gene3D G3DSA:1.10.287.130 225 296 8.2E-8 T 29-03-2018 THSYN_RS14790 557e49bf774a06f1182337829e8eacb2 458 SUPERFAMILY SSF55874 296 450 1.44E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14790 557e49bf774a06f1182337829e8eacb2 458 SMART SM00387 341 448 3.0E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14790 557e49bf774a06f1182337829e8eacb2 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 446 8.0E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS25200 374e0227c0e5248143bf35e0dd618459 428 Pfam PF00005 ABC transporter 64 195 8.8E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS25200 374e0227c0e5248143bf35e0dd618459 428 Gene3D G3DSA:3.40.50.300 1 290 9.2E-51 T 29-03-2018 THSYN_RS25200 374e0227c0e5248143bf35e0dd618459 428 SMART SM00382 73 245 9.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS25200 374e0227c0e5248143bf35e0dd618459 428 SUPERFAMILY SSF52540 59 258 8.84E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11980 0abe2a86556ff65c659fe8b927c847bb 290 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 4 189 2.6E-47 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 THSYN_RS11980 0abe2a86556ff65c659fe8b927c847bb 290 SUPERFAMILY SSF54913 219 290 1.11E-16 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THSYN_RS11980 0abe2a86556ff65c659fe8b927c847bb 290 Gene3D G3DSA:3.30.70.120 221 290 1.2E-19 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THSYN_RS11980 0abe2a86556ff65c659fe8b927c847bb 290 Gene3D G3DSA:3.40.190.10 121 216 4.0E-17 T 29-03-2018 THSYN_RS11980 0abe2a86556ff65c659fe8b927c847bb 290 Pfam PF08029 HisG, C-terminal domain 216 288 7.1E-22 T 29-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 THSYN_RS11980 0abe2a86556ff65c659fe8b927c847bb 290 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 190 289 1.5E-28 T 29-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 THSYN_RS11980 0abe2a86556ff65c659fe8b927c847bb 290 Pfam PF01634 ATP phosphoribosyltransferase 50 211 6.2E-38 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 THSYN_RS11980 0abe2a86556ff65c659fe8b927c847bb 290 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 3 290 26.886 T 29-03-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 THSYN_RS11980 0abe2a86556ff65c659fe8b927c847bb 290 SUPERFAMILY SSF53850 3 216 2.38E-56 T 29-03-2018 THSYN_RS11980 0abe2a86556ff65c659fe8b927c847bb 290 Gene3D G3DSA:3.40.190.10 1 120 1.1E-31 T 29-03-2018 THSYN_RS08740 a34b2a7e75cf04b1d97035322f843938 846 Gene3D G3DSA:2.60.40.10 409 535 9.8E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS11345 dcda0f9998527255df299d7270ac473c 97 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 16 77 1.0E-12 T 29-03-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system THSYN_RS11345 dcda0f9998527255df299d7270ac473c 97 Gene3D G3DSA:1.10.1220.10 16 80 3.4E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS08280 de8b6a399a3f0b1cf05a843732533c2e 356 Gene3D G3DSA:3.20.20.70 7 354 3.8E-115 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS08280 de8b6a399a3f0b1cf05a843732533c2e 356 Pfam PF00793 DAHP synthetase I family 44 338 2.7E-85 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THSYN_RS08280 de8b6a399a3f0b1cf05a843732533c2e 356 PIRSF PIRSF001361 1 353 7.9E-150 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 THSYN_RS08280 de8b6a399a3f0b1cf05a843732533c2e 356 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 5 347 3.6E-137 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 THSYN_RS08280 de8b6a399a3f0b1cf05a843732533c2e 356 SUPERFAMILY SSF51569 6 347 5.02E-124 T 29-03-2018 THSYN_RS01735 1da90fa189da018842292927d478b8a7 93 Gene3D G3DSA:2.60.120.10 2 92 4.1E-13 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS01735 1da90fa189da018842292927d478b8a7 93 Pfam PF05899 Protein of unknown function (DUF861) 21 90 1.9E-24 T 29-03-2018 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 THSYN_RS01735 1da90fa189da018842292927d478b8a7 93 SUPERFAMILY SSF51182 24 90 2.23E-15 T 29-03-2018 IPR011051 RmlC-like cupin domain THSYN_RS15805 3b49c9b990db95f977113db73b085f41 264 Pfam PF12679 ABC-2 family transporter protein 77 213 5.6E-9 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 THSYN_RS16645 37ae6923e18493b4faa16fe7765537d5 1002 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 446 452 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS16645 37ae6923e18493b4faa16fe7765537d5 1002 Gene3D G3DSA:3.40.50.150 293 632 1.0E-22 T 29-03-2018 THSYN_RS16645 37ae6923e18493b4faa16fe7765537d5 1002 SUPERFAMILY SSF53335 151 414 1.86E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS16645 37ae6923e18493b4faa16fe7765537d5 1002 SUPERFAMILY SSF53335 441 569 1.86E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS16645 37ae6923e18493b4faa16fe7765537d5 1002 Pfam PF02384 N-6 DNA Methylase 274 543 4.1E-15 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS16645 37ae6923e18493b4faa16fe7765537d5 1002 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 443 455 7.1E-11 T 29-03-2018 THSYN_RS16645 37ae6923e18493b4faa16fe7765537d5 1002 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 295 311 7.1E-11 T 29-03-2018 THSYN_RS16645 37ae6923e18493b4faa16fe7765537d5 1002 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 326 340 7.1E-11 T 29-03-2018 THSYN_RS28295 c6e09b24037c2f97f95972ecaaa46830 144 Pfam PF00565 Staphylococcal nuclease homologue 31 127 5.9E-13 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold THSYN_RS28295 c6e09b24037c2f97f95972ecaaa46830 144 SMART SM00318 5 128 1.5E-15 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold THSYN_RS28295 c6e09b24037c2f97f95972ecaaa46830 144 SUPERFAMILY SSF50199 8 129 6.41E-28 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold THSYN_RS28295 c6e09b24037c2f97f95972ecaaa46830 144 Gene3D G3DSA:2.40.50.90 3 135 7.7E-26 T 29-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain THSYN_RS32285 028ce9fcb634016cf7d72ca500b5ff74 340 Pfam PF13343 Bacterial extracellular solute-binding protein 98 313 2.4E-25 T 29-03-2018 THSYN_RS32285 028ce9fcb634016cf7d72ca500b5ff74 340 PIRSF PIRSF002825 9 340 2.0E-78 T 29-03-2018 IPR026045 Ferric binding protein THSYN_RS32285 028ce9fcb634016cf7d72ca500b5ff74 340 Gene3D G3DSA:3.40.190.10 145 294 6.8E-33 T 29-03-2018 THSYN_RS32285 028ce9fcb634016cf7d72ca500b5ff74 340 SUPERFAMILY SSF53850 30 330 2.92E-70 T 29-03-2018 THSYN_RS32285 028ce9fcb634016cf7d72ca500b5ff74 340 Gene3D G3DSA:3.40.190.10 27 144 4.4E-10 T 29-03-2018 THSYN_RS32545 4f1fa3d1fbc493a87162c903ccabb034 631 SMART SM00327 447 623 2.4E-15 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS32545 4f1fa3d1fbc493a87162c903ccabb034 631 Gene3D G3DSA:1.10.8.300 197 327 2.3E-12 T 29-03-2018 THSYN_RS32545 4f1fa3d1fbc493a87162c903ccabb034 631 Gene3D G3DSA:3.40.50.410 441 626 2.7E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS32545 4f1fa3d1fbc493a87162c903ccabb034 631 SUPERFAMILY SSF53300 449 617 4.15E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS32545 4f1fa3d1fbc493a87162c903ccabb034 631 Pfam PF13519 von Willebrand factor type A domain 451 553 1.8E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS32545 4f1fa3d1fbc493a87162c903ccabb034 631 SUPERFAMILY SSF52540 74 281 1.2E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27455 f311d97da4d6973aa7952d1677230c40 462 SUPERFAMILY SSF53098 57 400 2.12E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS27455 f311d97da4d6973aa7952d1677230c40 462 Pfam PF13546 DDE superfamily endonuclease 28 290 5.7E-29 T 29-03-2018 THSYN_RS27455 f311d97da4d6973aa7952d1677230c40 462 Gene3D G3DSA:3.90.350.10 98 369 1.2E-13 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS15660 f311d97da4d6973aa7952d1677230c40 462 SUPERFAMILY SSF53098 57 400 2.12E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS15660 f311d97da4d6973aa7952d1677230c40 462 Pfam PF13546 DDE superfamily endonuclease 28 290 5.7E-29 T 29-03-2018 THSYN_RS15660 f311d97da4d6973aa7952d1677230c40 462 Gene3D G3DSA:3.90.350.10 98 369 1.2E-13 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS05020 f311d97da4d6973aa7952d1677230c40 462 SUPERFAMILY SSF53098 57 400 2.12E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS05020 f311d97da4d6973aa7952d1677230c40 462 Pfam PF13546 DDE superfamily endonuclease 28 290 5.7E-29 T 29-03-2018 THSYN_RS05020 f311d97da4d6973aa7952d1677230c40 462 Gene3D G3DSA:3.90.350.10 98 369 1.2E-13 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS30150 f311d97da4d6973aa7952d1677230c40 462 SUPERFAMILY SSF53098 57 400 2.12E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS30150 f311d97da4d6973aa7952d1677230c40 462 Pfam PF13546 DDE superfamily endonuclease 28 290 5.7E-29 T 29-03-2018 THSYN_RS30150 f311d97da4d6973aa7952d1677230c40 462 Gene3D G3DSA:3.90.350.10 98 369 1.2E-13 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS07725 f311d97da4d6973aa7952d1677230c40 462 SUPERFAMILY SSF53098 57 400 2.12E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS07725 f311d97da4d6973aa7952d1677230c40 462 Pfam PF13546 DDE superfamily endonuclease 28 290 5.7E-29 T 29-03-2018 THSYN_RS07725 f311d97da4d6973aa7952d1677230c40 462 Gene3D G3DSA:3.90.350.10 98 369 1.2E-13 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS16215 7e4d7f40735ef893e38a0f9e1e14bc9b 58 Pfam PF01783 Ribosomal L32p protein family 2 56 1.3E-21 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS16215 7e4d7f40735ef893e38a0f9e1e14bc9b 58 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 18.266 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS16215 7e4d7f40735ef893e38a0f9e1e14bc9b 58 SUPERFAMILY SSF57829 2 55 1.1E-19 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 THSYN_RS16215 7e4d7f40735ef893e38a0f9e1e14bc9b 58 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 4.4E-21 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS09985 862af9d87ae427b6f607856e80476c35 752 Gene3D G3DSA:3.40.50.410 22 211 2.5E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS09985 862af9d87ae427b6f607856e80476c35 752 SUPERFAMILY SSF53300 26 194 5.38E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS05005 e0bfecb8e784e3e4ad7a414a0b9bc690 145 Pfam PF01814 Hemerythrin HHE cation binding domain 5 127 2.1E-18 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THSYN_RS05005 e0bfecb8e784e3e4ad7a414a0b9bc690 145 Gene3D G3DSA:1.20.120.520 3 138 1.0E-16 T 29-03-2018 THSYN_RS11770 d1fc239f880a7ac32d71c626f7354633 241 Pfam PF02167 Cytochrome C1 family 34 240 4.1E-20 T 29-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 THSYN_RS11770 d1fc239f880a7ac32d71c626f7354633 241 Gene3D G3DSA:1.20.5.100 210 240 6.5E-15 T 29-03-2018 THSYN_RS11770 d1fc239f880a7ac32d71c626f7354633 241 Gene3D G3DSA:1.10.760.10 24 206 1.9E-53 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS11770 d1fc239f880a7ac32d71c626f7354633 241 SUPERFAMILY SSF46626 26 205 2.47E-45 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS11770 d1fc239f880a7ac32d71c626f7354633 241 PRINTS PR00603 Cytochrome C1 signature 42 61 3.0E-7 T 29-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 THSYN_RS11770 d1fc239f880a7ac32d71c626f7354633 241 PRINTS PR00603 Cytochrome C1 signature 206 221 3.0E-7 T 29-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 THSYN_RS11770 d1fc239f880a7ac32d71c626f7354633 241 PRINTS PR00603 Cytochrome C1 signature 187 206 3.0E-7 T 29-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 THSYN_RS20685 1b8864152b46daf4e2da7f5413ff6633 78 SUPERFAMILY SSF143800 2 76 1.29E-30 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20685 1b8864152b46daf4e2da7f5413ff6633 78 Gene3D G3DSA:2.30.170.40 2 75 2.0E-28 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20685 1b8864152b46daf4e2da7f5413ff6633 78 Pfam PF00830 Ribosomal L28 family 3 61 9.2E-28 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20685 1b8864152b46daf4e2da7f5413ff6633 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 20.476 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS20685 1b8864152b46daf4e2da7f5413ff6633 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 1.2E-27 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS26580 23d4ebbd37c7bc42bc0e34c7e856eaae 166 SUPERFAMILY SSF46785 2 133 6.81E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26580 23d4ebbd37c7bc42bc0e34c7e856eaae 166 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 134 2.4E-63 T 29-03-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 THSYN_RS26580 23d4ebbd37c7bc42bc0e34c7e856eaae 166 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 1.7E-46 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type THSYN_RS26580 23d4ebbd37c7bc42bc0e34c7e856eaae 166 Pfam PF02082 Transcriptional regulator 1 83 9.7E-27 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type THSYN_RS26580 23d4ebbd37c7bc42bc0e34c7e856eaae 166 Gene3D G3DSA:1.10.10.10 1 140 2.2E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS20545 cc62fb76d6441a49a052ff6fb35926bc 384 Gene3D G3DSA:3.30.470.20 180 378 5.8E-42 T 29-03-2018 THSYN_RS20545 cc62fb76d6441a49a052ff6fb35926bc 384 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 10 362 40.271 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 THSYN_RS20545 cc62fb76d6441a49a052ff6fb35926bc 384 SUPERFAMILY SSF56059 107 300 3.54E-48 T 29-03-2018 THSYN_RS20545 cc62fb76d6441a49a052ff6fb35926bc 384 Gene3D G3DSA:3.30.1490.20 122 179 7.0E-9 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS20545 cc62fb76d6441a49a052ff6fb35926bc 384 SUPERFAMILY SSF52440 9 104 1.58E-29 T 29-03-2018 IPR016185 Pre-ATP-grasp domain THSYN_RS20545 cc62fb76d6441a49a052ff6fb35926bc 384 Pfam PF02222 ATP-grasp domain 117 280 8.0E-44 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type THSYN_RS20545 cc62fb76d6441a49a052ff6fb35926bc 384 Gene3D G3DSA:3.40.50.20 10 106 2.8E-27 T 29-03-2018 THSYN_RS20545 cc62fb76d6441a49a052ff6fb35926bc 384 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 11 365 1.3E-119 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 THSYN_RS20545 cc62fb76d6441a49a052ff6fb35926bc 384 SUPERFAMILY SSF51246 306 378 6.43E-15 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THSYN_RS24535 f919ade559ecc581833e2f0371d16d5f 145 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 142 2.6E-34 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS24535 f919ade559ecc581833e2f0371d16d5f 145 SUPERFAMILY SSF52788 3 142 1.96E-38 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS24535 f919ade559ecc581833e2f0371d16d5f 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 101 114 1.0E-19 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS24535 f919ade559ecc581833e2f0371d16d5f 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 79 94 1.0E-19 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS24535 f919ade559ecc581833e2f0371d16d5f 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 45 61 1.0E-19 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS24535 f919ade559ecc581833e2f0371d16d5f 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 116 131 1.0E-19 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS24535 f919ade559ecc581833e2f0371d16d5f 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 1.0E-19 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS24535 f919ade559ecc581833e2f0371d16d5f 145 SMART SM00226 3 144 2.2E-40 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS24535 f919ade559ecc581833e2f0371d16d5f 145 Gene3D G3DSA:3.40.50.2300 2 145 8.7E-42 T 29-03-2018 THSYN_RS14660 b0b8703aa3f0773bb4d976d5a4a13200 298 Pfam PF07610 Protein of unknown function (DUF1573) 63 140 8.9E-6 T 29-03-2018 IPR011467 Protein of unknown function DUF1573 THSYN_RS14660 b0b8703aa3f0773bb4d976d5a4a13200 298 Gene3D G3DSA:2.60.40.10 53 157 3.3E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS13495 98c5c2d01e13cf861a729fcdc232ecae 193 Pfam PF05685 Putative restriction endonuclease 20 172 5.7E-32 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS13495 98c5c2d01e13cf861a729fcdc232ecae 193 SUPERFAMILY SSF52980 2 170 1.23E-24 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS13495 98c5c2d01e13cf861a729fcdc232ecae 193 Gene3D G3DSA:3.90.1570.10 2 189 1.5E-43 T 29-03-2018 THSYN_RS15790 d24db7353404f026c501835b4f94b593 83 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 9.6E-31 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THSYN_RS15790 d24db7353404f026c501835b4f94b593 83 Gene3D G3DSA:2.30.30.100 4 73 1.7E-34 T 29-03-2018 THSYN_RS15790 d24db7353404f026c501835b4f94b593 83 Pfam PF17209 Hfq protein 7 69 4.9E-32 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THSYN_RS15790 d24db7353404f026c501835b4f94b593 83 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 64 28.172 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THSYN_RS15790 d24db7353404f026c501835b4f94b593 83 SUPERFAMILY SSF50182 7 69 5.58E-25 T 29-03-2018 IPR010920 LSM domain THSYN_RS32730 f9856adfbd55cf27f08c6fb0b06f675b 404 Pfam PF02687 FtsX-like permease family 302 397 2.2E-7 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THSYN_RS15895 3cc76a8bfdb8742792192b06a4bf7c17 221 Gene3D G3DSA:3.30.70.270 72 218 5.9E-36 T 29-03-2018 THSYN_RS15895 3cc76a8bfdb8742792192b06a4bf7c17 221 Pfam PF00990 Diguanylate cyclase, GGDEF domain 79 212 4.5E-29 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS15895 3cc76a8bfdb8742792192b06a4bf7c17 221 SUPERFAMILY SSF55073 77 215 2.04E-34 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS15895 3cc76a8bfdb8742792192b06a4bf7c17 221 SMART SM00267 56 217 6.7E-28 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS15895 3cc76a8bfdb8742792192b06a4bf7c17 221 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 77 216 2.7E-32 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SUPERFAMILY SSF55785 577 693 9.18E-21 T 29-03-2018 IPR000014 PAS domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Pfam PF01590 GAF domain 722 864 4.3E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Gene3D G3DSA:3.30.450.20 874 1004 4.6E-28 T 29-03-2018 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Pfam PF08448 PAS fold 895 995 1.4E-14 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SMART SM00091 442 510 0.15 T 29-03-2018 IPR000014 PAS domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SMART SM00091 571 640 0.0045 T 29-03-2018 IPR000014 PAS domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SMART SM00091 879 945 3.8E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SUPERFAMILY SSF52172 1434 1552 4.98E-26 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Gene3D G3DSA:3.30.450.20 696 723 0.048 T 29-03-2018 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SUPERFAMILY SSF55785 451 562 1.92E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Gene3D G3DSA:1.10.287.130 1165 1240 2.1E-4 T 29-03-2018 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SMART SM00387 1284 1407 5.9E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SMART SM00065 721 875 9.8E-17 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Gene3D G3DSA:3.30.450.40 724 873 1.4E-20 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 569 697 4.8E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 439 566 1.7E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 875 998 2.4E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Pfam PF00072 Response regulator receiver domain 1438 1547 1.7E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SMART SM00448 1436 1547 2.2E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Gene3D G3DSA:3.30.565.10 1244 1407 7.7E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Gene3D G3DSA:3.40.50.2300 1433 1554 3.6E-26 T 29-03-2018 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SUPERFAMILY SSF55874 1235 1406 9.17E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Pfam PF08447 PAS fold 465 552 3.1E-12 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Pfam PF08447 PAS fold 594 684 2.0E-16 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SUPERFAMILY SSF55781 722 877 2.62E-20 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SUPERFAMILY SSF55785 866 992 2.58E-24 T 29-03-2018 IPR000014 PAS domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SMART SM00086 647 690 6.6E-10 T 29-03-2018 IPR001610 PAC motif THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SMART SM00086 517 559 0.033 T 29-03-2018 IPR001610 PAC motif THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 SMART SM00086 952 994 4.6 T 29-03-2018 IPR001610 PAC motif THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Gene3D G3DSA:3.30.450.40 1005 1164 0.011 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Gene3D G3DSA:3.30.450.20 564 695 7.7E-32 T 29-03-2018 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Gene3D G3DSA:3.30.450.20 411 563 6.4E-23 T 29-03-2018 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1286 1405 9.0E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1391 1404 2.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1336 1350 2.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1354 1364 2.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00560 d28a60cd01f7458bd00a41c91691831c 1555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1367 1385 2.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 Pfam PF08477 Ras of Complex, Roc, domain of DAPkinase 413 539 7.8E-21 T 29-03-2018 THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 Pfam PF13676 TIR domain 908 1008 3.6E-8 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 SUPERFAMILY SSF52200 905 1017 2.09E-11 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 Gene3D G3DSA:3.40.50.300 409 591 3.3E-17 T 29-03-2018 THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 SUPERFAMILY SSF52058 31 379 1.02E-50 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 Gene3D G3DSA:3.80.10.10 229 372 2.9E-21 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 PRINTS PR00449 Transforming protein P21 ras signature 455 477 1.5E-6 T 29-03-2018 THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 PRINTS PR00449 Transforming protein P21 ras signature 412 433 1.5E-6 T 29-03-2018 THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 PRINTS PR00449 Transforming protein P21 ras signature 527 540 1.5E-6 T 29-03-2018 THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 Pfam PF16095 C-terminal of Roc, COR, domain 629 820 1.2E-19 T 29-03-2018 IPR032171 C-terminal of Roc (COR) domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 SUPERFAMILY SSF52540 411 595 2.65E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 Gene3D G3DSA:3.80.10.10 1 228 2.4E-35 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 Pfam PF12799 Leucine Rich repeats (2 copies) 295 335 3.5E-6 T 29-03-2018 IPR025875 Leucine rich repeat 4 THSYN_RS08030 1781ed3b1cda4545df7048f863c21e8d 1095 Gene3D G3DSA:3.40.50.10140 902 1039 1.4E-13 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS04215 730d370e402395ce81eba1301885e14f 75 Gene3D G3DSA:1.20.5.30 58 75 0.0064 T 29-03-2018 THSYN_RS04215 730d370e402395ce81eba1301885e14f 75 SUPERFAMILY SSF57997 14 74 2.58E-6 T 29-03-2018 THSYN_RS04215 730d370e402395ce81eba1301885e14f 75 Gene3D G3DSA:1.20.1270.70 13 57 9.2E-7 T 29-03-2018 THSYN_RS12945 fc789274867632f7ea80413c3cc428fe 786 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 13 708 1.0E-183 T 29-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 THSYN_RS12945 fc789274867632f7ea80413c3cc428fe 786 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 9 29 5.1E-8 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS12945 fc789274867632f7ea80413c3cc428fe 786 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 30 48 5.1E-8 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS12945 fc789274867632f7ea80413c3cc428fe 786 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 57 72 5.1E-8 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS12945 fc789274867632f7ea80413c3cc428fe 786 SUPERFAMILY SSF52540 7 175 1.49E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12945 fc789274867632f7ea80413c3cc428fe 786 Gene3D G3DSA:3.40.50.300 2 304 2.0E-37 T 29-03-2018 THSYN_RS12945 fc789274867632f7ea80413c3cc428fe 786 Pfam PF07670 Nucleoside recognition 523 710 7.3E-30 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 THSYN_RS12945 fc789274867632f7ea80413c3cc428fe 786 Pfam PF07670 Nucleoside recognition 362 454 2.5E-14 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 THSYN_RS12945 fc789274867632f7ea80413c3cc428fe 786 Pfam PF07664 Ferrous iron transport protein B C terminus 465 517 4.4E-23 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 THSYN_RS12945 fc789274867632f7ea80413c3cc428fe 786 Pfam PF02421 Ferrous iron transport protein B 8 168 2.9E-63 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 THSYN_RS12945 fc789274867632f7ea80413c3cc428fe 786 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 170 5.4E-15 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS23920 29b83950c94eaff6f509cb51fcacf297 103 SUPERFAMILY SSF54999 5 102 7.59E-37 T 29-03-2018 IPR027486 Ribosomal protein S10 domain THSYN_RS23920 29b83950c94eaff6f509cb51fcacf297 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 3.8E-46 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23920 29b83950c94eaff6f509cb51fcacf297 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.244 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23920 29b83950c94eaff6f509cb51fcacf297 103 Gene3D G3DSA:3.30.70.600 3 103 1.0E-36 T 29-03-2018 IPR027486 Ribosomal protein S10 domain THSYN_RS23920 29b83950c94eaff6f509cb51fcacf297 103 SMART SM01403 7 101 1.4E-56 T 29-03-2018 IPR027486 Ribosomal protein S10 domain THSYN_RS23920 29b83950c94eaff6f509cb51fcacf297 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.7E-35 T 29-03-2018 IPR027486 Ribosomal protein S10 domain THSYN_RS23920 29b83950c94eaff6f509cb51fcacf297 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.6E-17 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23920 29b83950c94eaff6f509cb51fcacf297 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.6E-17 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23920 29b83950c94eaff6f509cb51fcacf297 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.6E-17 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 582 608 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 413 426 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 Pfam PF04539 Sigma-70 region 3 468 544 6.0E-30 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 Pfam PF03979 Sigma-70 factor, region 1.1 4 80 1.4E-27 T 29-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 Gene3D G3DSA:1.10.601.10 115 458 8.4E-102 T 29-03-2018 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 Gene3D G3DSA:1.10.601.10 2 114 9.9E-14 T 29-03-2018 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 Pfam PF04542 Sigma-70 region 2 389 458 1.7E-21 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 Pfam PF04546 Sigma-70, non-essential region 139 358 8.9E-56 T 29-03-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 Gene3D G3DSA:1.10.10.10 551 622 8.8E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 Gene3D G3DSA:1.10.10.10 459 509 2.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 Pfam PF00140 Sigma-70 factor, region 1.2 98 129 3.9E-12 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 5 622 44.191 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 385 610 5.2E-38 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 SUPERFAMILY SSF88659 462 535 1.18E-20 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 SUPERFAMILY SSF88659 519 621 1.38E-26 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 SUPERFAMILY SSF88946 115 456 1.57E-91 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 Pfam PF04545 Sigma-70, region 4 558 610 1.8E-18 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 PRINTS PR00046 Major sigma-70 factor signature 437 445 6.1E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 PRINTS PR00046 Major sigma-70 factor signature 597 608 6.1E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 PRINTS PR00046 Major sigma-70 factor signature 561 573 6.1E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 PRINTS PR00046 Major sigma-70 factor signature 413 426 6.1E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 PRINTS PR00046 Major sigma-70 factor signature 582 597 6.1E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS20965 0f503f361ecb89f7e0eb685d932cf964 624 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 385 621 9.3E-121 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 THSYN_RS05410 f3703f91f766665a1bce2ea7274499fc 171 Gene3D G3DSA:3.90.1340.10 1 65 2.5E-19 T 29-03-2018 IPR011083 Phage tail collar domain THSYN_RS05410 f3703f91f766665a1bce2ea7274499fc 171 Pfam PF07484 Phage Tail Collar Domain 8 63 1.1E-25 T 29-03-2018 IPR011083 Phage tail collar domain THSYN_RS05410 f3703f91f766665a1bce2ea7274499fc 171 SUPERFAMILY SSF88874 1 165 1.7E-45 T 29-03-2018 THSYN_RS29230 0ba8a61e577769a32c628927903eb5e8 107 Gene3D G3DSA:1.10.1220.10 8 50 2.1E-11 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS29230 0ba8a61e577769a32c628927903eb5e8 107 Gene3D G3DSA:1.20.890.30 54 89 5.9E-16 T 29-03-2018 THSYN_RS29230 0ba8a61e577769a32c628927903eb5e8 107 Pfam PF08681 Protein of unknown function (DUF1778) 10 87 2.8E-23 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 THSYN_RS29230 0ba8a61e577769a32c628927903eb5e8 107 SUPERFAMILY SSF47598 8 84 2.52E-20 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS27310 eee2af16a8086b98fc1f41ab1296fa64 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 24.66 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS27310 eee2af16a8086b98fc1f41ab1296fa64 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 78 4.1E-30 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS27310 eee2af16a8086b98fc1f41ab1296fa64 90 Gene3D G3DSA:3.30.1320.10 1 79 8.7E-31 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS27310 eee2af16a8086b98fc1f41ab1296fa64 90 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 29-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS27310 eee2af16a8086b98fc1f41ab1296fa64 90 Pfam PF00886 Ribosomal protein S16 8 68 6.6E-24 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS27310 eee2af16a8086b98fc1f41ab1296fa64 90 SUPERFAMILY SSF54565 1 78 4.32E-29 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS17530 8bb2bf4860777a9ac9461498d5e6079e 399 Pfam PF07282 Putative transposase DNA-binding domain 291 360 2.5E-22 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal THSYN_RS17530 8bb2bf4860777a9ac9461498d5e6079e 399 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 246 318 1.5E-8 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal THSYN_RS17530 8bb2bf4860777a9ac9461498d5e6079e 399 Pfam PF12323 Helix-turn-helix domain 1 43 4.0E-13 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain THSYN_RS17530 8bb2bf4860777a9ac9461498d5e6079e 399 Pfam PF01385 Probable transposase 166 277 4.8E-28 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 SUPERFAMILY SSF47384 315 396 5.1E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 SMART SM00086 248 290 4.6E-4 T 29-03-2018 IPR001610 PAC motif THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 Gene3D G3DSA:3.30.565.10 399 558 6.9E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 Pfam PF08448 PAS fold 180 292 1.6E-14 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 SUPERFAMILY SSF55874 384 549 4.85E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 Gene3D G3DSA:3.30.450.20 16 162 6.7E-13 T 29-03-2018 THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 SMART SM00387 441 553 6.7E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 SUPERFAMILY SSF55785 161 288 2.09E-23 T 29-03-2018 IPR000014 PAS domain THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 Gene3D G3DSA:1.10.287.130 320 391 4.1E-18 T 29-03-2018 THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 Pfam PF00512 His Kinase A (phospho-acceptor) domain 328 395 3.0E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 550 1.6E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 507 1.6E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 531 1.6E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 493 1.6E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 171 297 9.5E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 SMART SM00388 328 395 7.4E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 Gene3D G3DSA:3.30.450.20 163 319 3.7E-29 T 29-03-2018 THSYN_RS14195 468ddde858ff05fe809d79659c0b2a7d 582 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 442 551 5.5E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS22080 eec10fad141ca995b67e75148b564d6c 239 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 4 235 39.481 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THSYN_RS22080 eec10fad141ca995b67e75148b564d6c 239 SUPERFAMILY SSF51366 5 233 1.15E-75 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THSYN_RS22080 eec10fad141ca995b67e75148b564d6c 239 SMART SM00934 6 230 1.1E-97 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THSYN_RS22080 eec10fad141ca995b67e75148b564d6c 239 Gene3D G3DSA:3.20.20.70 1 235 8.6E-71 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS22080 eec10fad141ca995b67e75148b564d6c 239 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 8 230 8.0E-56 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THSYN_RS22080 eec10fad141ca995b67e75148b564d6c 239 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 58 71 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THSYN_RS22080 eec10fad141ca995b67e75148b564d6c 239 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 6 229 2.1E-48 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 Pfam PF00575 S1 RNA binding domain 646 717 1.6E-21 T 29-03-2018 IPR003029 S1 domain GO:0003676 THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 SUPERFAMILY SSF47781 467 555 2.0E-24 T 29-03-2018 IPR010994 RuvA domain 2-like THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 Pfam PF09371 Tex-like protein N-terminal domain 8 191 3.6E-68 T 29-03-2018 IPR018974 Tex-like protein, N-terminal THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 Gene3D G3DSA:1.10.150.310 496 627 1.5E-38 T 29-03-2018 THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 SUPERFAMILY SSF158832 2 317 4.58E-114 T 29-03-2018 THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 SUPERFAMILY SSF50249 635 723 8.95E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 Pfam PF12836 Helix-hairpin-helix motif 488 552 7.6E-23 T 29-03-2018 THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 Gene3D G3DSA:1.10.10.650 1 101 1.0E-34 T 29-03-2018 IPR023319 Tex-like protein, HTH domain THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 SUPERFAMILY SSF53098 318 466 3.49E-47 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 SUPERFAMILY SSF47781 557 629 2.45E-19 T 29-03-2018 IPR010994 RuvA domain 2-like THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 Gene3D G3DSA:1.10.3500.10 102 352 5.5E-71 T 29-03-2018 IPR023323 Tex-like domain THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 Gene3D G3DSA:2.40.50.140 640 722 4.2E-26 T 29-03-2018 THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 SMART SM00316 646 717 9.4E-27 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 Gene3D G3DSA:1.10.3500.10 353 495 6.8E-40 T 29-03-2018 IPR023323 Tex-like domain THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 SMART SM00732 322 421 1.7E-32 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 THSYN_RS14490 2de28f78d2a07d1748b545581cbf4436 787 Pfam PF16921 Tex protein YqgF-like domain 324 448 7.1E-50 T 29-03-2018 IPR032639 Tex protein, YqgF-like domain THSYN_RS29870 81ed0b898164d545660fcb59bc5f1438 693 Pfam PF07085 DRTGG domain 204 315 4.5E-26 T 29-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS29870 81ed0b898164d545660fcb59bc5f1438 693 Pfam PF01515 Phosphate acetyl/butaryl transferase 361 676 2.1E-118 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS29870 81ed0b898164d545660fcb59bc5f1438 693 SUPERFAMILY SSF75138 200 318 1.73E-19 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like THSYN_RS29870 81ed0b898164d545660fcb59bc5f1438 693 Pfam PF13500 AAA domain 7 201 3.2E-29 T 29-03-2018 THSYN_RS29870 81ed0b898164d545660fcb59bc5f1438 693 PIRSF PIRSF006107 5 684 2.2E-288 T 29-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS29870 81ed0b898164d545660fcb59bc5f1438 693 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 376 676 2.9E-123 T 29-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS29870 81ed0b898164d545660fcb59bc5f1438 693 Gene3D G3DSA:3.40.50.10750 499 652 2.3E-61 T 29-03-2018 THSYN_RS29870 81ed0b898164d545660fcb59bc5f1438 693 SUPERFAMILY SSF52540 8 211 2.88E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29870 81ed0b898164d545660fcb59bc5f1438 693 SUPERFAMILY SSF53659 362 680 1.07E-89 T 29-03-2018 THSYN_RS29870 81ed0b898164d545660fcb59bc5f1438 693 Gene3D G3DSA:3.40.50.300 5 200 9.2E-29 T 29-03-2018 THSYN_RS29870 81ed0b898164d545660fcb59bc5f1438 693 Gene3D G3DSA:3.40.1390.20 201 337 1.9E-23 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 PRINTS PR01033 Phytochrome signature 457 475 2.2E-16 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 PRINTS PR01033 Phytochrome signature 423 442 2.2E-16 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 PRINTS PR01033 Phytochrome signature 154 173 2.2E-16 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 PRINTS PR01033 Phytochrome signature 335 355 2.2E-16 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 PRINTS PR01033 Phytochrome signature 237 258 2.2E-16 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 SMART SM00065 139 313 6.9E-4 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 Gene3D G3DSA:3.30.450.40 125 301 4.6E-31 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 SUPERFAMILY SSF55781 322 494 2.66E-37 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 Pfam PF08446 PAS fold 13 68 1.5E-5 T 29-03-2018 IPR013654 PAS fold-2 GO:0006355 THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 Pfam PF01590 GAF domain 146 294 7.9E-16 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 SUPERFAMILY SSF55785 6 112 4.4E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 SUPERFAMILY SSF55781 139 309 2.13E-47 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 Gene3D G3DSA:3.30.450.20 3 113 3.3E-5 T 29-03-2018 THSYN_RS02200 5972d953c072f6a5a01195c635288248 501 Pfam PF00360 Phytochrome region 329 493 2.1E-35 T 29-03-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 THSYN_RS18790 3c92eb982aac8d38ff2987cdebefa688 683 Gene3D G3DSA:2.40.160.50 324 682 8.4E-49 T 29-03-2018 THSYN_RS18790 3c92eb982aac8d38ff2987cdebefa688 683 Gene3D G3DSA:3.10.20.310 203 286 4.3E-8 T 29-03-2018 THSYN_RS18790 3c92eb982aac8d38ff2987cdebefa688 683 Pfam PF17243 POTRA domain TamA domain 1 120 201 1.3E-15 T 29-03-2018 IPR035243 TamA, POTRA domain 1 THSYN_RS18790 3c92eb982aac8d38ff2987cdebefa688 683 Pfam PF01103 Surface antigen 480 680 6.3E-28 T 29-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 THSYN_RS18790 3c92eb982aac8d38ff2987cdebefa688 683 Pfam PF07244 Surface antigen variable number repeat 290 347 9.8E-5 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THSYN_RS16350 059cfb0983ec74d55d5e414fed4161b3 480 Pfam PF04851 Type III restriction enzyme, res subunit 254 421 2.2E-18 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS16350 059cfb0983ec74d55d5e414fed4161b3 480 SMART SM00487 252 441 2.3E-13 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS16350 059cfb0983ec74d55d5e414fed4161b3 480 Gene3D G3DSA:3.40.50.300 247 424 2.5E-24 T 29-03-2018 THSYN_RS16350 059cfb0983ec74d55d5e414fed4161b3 480 Pfam PF13091 PLD-like domain 39 201 1.7E-7 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THSYN_RS16350 059cfb0983ec74d55d5e414fed4161b3 480 SUPERFAMILY SSF52540 227 421 5.07E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24770 d73ca019760ad7bde2207b228ebf6718 181 Gene3D G3DSA:3.30.70.20 145 170 3.1E-5 T 29-03-2018 THSYN_RS24770 d73ca019760ad7bde2207b228ebf6718 181 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 144 155 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS24770 d73ca019760ad7bde2207b228ebf6718 181 PIRSF PIRSF005784 4 181 9.6E-59 T 29-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 THSYN_RS24770 d73ca019760ad7bde2207b228ebf6718 181 Pfam PF04060 Putative Fe-S cluster 45 77 7.3E-10 T 29-03-2018 IPR007202 4Fe-4S domain GO:0051536 THSYN_RS24770 d73ca019760ad7bde2207b228ebf6718 181 Pfam PF14697 4Fe-4S dicluster domain 107 161 4.1E-14 T 29-03-2018 THSYN_RS24770 d73ca019760ad7bde2207b228ebf6718 181 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 6 177 7.1E-57 T 29-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 THSYN_RS24770 d73ca019760ad7bde2207b228ebf6718 181 SUPERFAMILY SSF54862 42 173 2.33E-26 T 29-03-2018 THSYN_RS24770 d73ca019760ad7bde2207b228ebf6718 181 Hamap MF_00463 Electron transport complex subunit RsxB [rsxB]. 5 181 35.504 T 29-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 THSYN_RS24770 d73ca019760ad7bde2207b228ebf6718 181 Gene3D G3DSA:3.30.70.20 123 144 4.2E-10 T 29-03-2018 THSYN_RS24770 d73ca019760ad7bde2207b228ebf6718 181 Gene3D G3DSA:3.30.70.20 25 122 3.7E-9 T 29-03-2018 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 SUPERFAMILY SSF82714 183 264 1.96E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 SUPERFAMILY SSF82866 792 1014 1.18E-43 T 29-03-2018 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 SUPERFAMILY SSF82866 290 491 4.58E-47 T 29-03-2018 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 SUPERFAMILY SSF82714 709 790 3.79E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 Gene3D G3DSA:3.30.2090.10 181 269 3.0E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 Gene3D G3DSA:3.30.2090.10 707 794 7.5E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 SUPERFAMILY SSF82693 40 131 8.37E-23 T 29-03-2018 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 SUPERFAMILY SSF82693 136 182 2.93E-23 T 29-03-2018 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 SUPERFAMILY SSF82693 268 324 2.93E-23 T 29-03-2018 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 Gene3D G3DSA:3.30.70.1430 40 141 1.6E-23 T 29-03-2018 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 Gene3D G3DSA:1.20.1640.10 281 501 9.9E-48 T 29-03-2018 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 Pfam PF00873 AcrB/AcrD/AcrF family 5 1012 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 Gene3D G3DSA:1.20.1640.10 813 1015 3.2E-32 T 29-03-2018 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 SUPERFAMILY SSF82693 556 652 2.04E-14 T 29-03-2018 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 Gene3D G3DSA:3.30.70.1430 559 656 5.3E-11 T 29-03-2018 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.2E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.2E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.2E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 1.2E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 PRINTS PR00702 Acriflavin resistance protein family signature 610 624 1.2E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.2E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.2E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS18695 a54e684bc4101cdfe55ae7e4cd77a7b7 1029 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-78 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS19075 1c7e79ebdad947c8cb3a962c67f463bb 614 Pfam PF00664 ABC transporter transmembrane region 34 294 2.3E-7 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS19075 1c7e79ebdad947c8cb3a962c67f463bb 614 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 14 542 1.3E-138 T 29-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 THSYN_RS19075 1c7e79ebdad947c8cb3a962c67f463bb 614 Pfam PF00005 ABC transporter 363 511 4.8E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS19075 1c7e79ebdad947c8cb3a962c67f463bb 614 Gene3D G3DSA:1.20.1560.10 6 336 1.1E-31 T 29-03-2018 THSYN_RS19075 1c7e79ebdad947c8cb3a962c67f463bb 614 Gene3D G3DSA:3.40.50.300 337 572 1.1E-67 T 29-03-2018 THSYN_RS19075 1c7e79ebdad947c8cb3a962c67f463bb 614 SUPERFAMILY SSF52540 338 571 1.59E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19075 1c7e79ebdad947c8cb3a962c67f463bb 614 SUPERFAMILY SSF90123 14 333 2.88E-42 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS19075 1c7e79ebdad947c8cb3a962c67f463bb 614 SMART SM00382 372 558 1.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS19075 1c7e79ebdad947c8cb3a962c67f463bb 614 ProSitePatterns PS00211 ABC transporters family signature. 484 498 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS08025 8a36bc1ee5ce681544b4ebda1505d105 269 Gene3D G3DSA:3.40.50.300 15 268 3.2E-51 T 29-03-2018 THSYN_RS08025 8a36bc1ee5ce681544b4ebda1505d105 269 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 247 268 2.3E-9 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal THSYN_RS08025 8a36bc1ee5ce681544b4ebda1505d105 269 SUPERFAMILY SSF52540 27 267 4.47E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08025 8a36bc1ee5ce681544b4ebda1505d105 269 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 28 269 9.8E-118 T 29-03-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD THSYN_RS08025 8a36bc1ee5ce681544b4ebda1505d105 269 Pfam PF00005 ABC transporter 44 199 7.8E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS28665 3f16ebb03237f9ea02ccd5494e185350 966 SMART SM00861 620 813 7.7E-57 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THSYN_RS28665 3f16ebb03237f9ea02ccd5494e185350 966 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 818 959 2.6E-47 T 29-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 THSYN_RS28665 3f16ebb03237f9ea02ccd5494e185350 966 SUPERFAMILY SSF52518 603 820 3.9E-49 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS28665 3f16ebb03237f9ea02ccd5494e185350 966 Pfam PF02779 Transketolase, pyrimidine binding domain 620 813 1.0E-62 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THSYN_RS28665 3f16ebb03237f9ea02ccd5494e185350 966 PIRSF PIRSF000157 2 961 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 THSYN_RS28665 3f16ebb03237f9ea02ccd5494e185350 966 Gene3D G3DSA:1.10.287.1150 107 189 9.9E-21 T 29-03-2018 THSYN_RS28665 3f16ebb03237f9ea02ccd5494e185350 966 Gene3D G3DSA:3.40.50.970 619 828 4.0E-55 T 29-03-2018 THSYN_RS28665 3f16ebb03237f9ea02ccd5494e185350 966 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 15 958 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 THSYN_RS28665 3f16ebb03237f9ea02ccd5494e185350 966 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 13 49 1.5E-13 T 29-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 THSYN_RS28665 3f16ebb03237f9ea02ccd5494e185350 966 Pfam PF00676 Dehydrogenase E1 component 238 543 4.7E-52 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 THSYN_RS28665 3f16ebb03237f9ea02ccd5494e185350 966 Gene3D G3DSA:3.40.50.970 190 551 4.7E-85 T 29-03-2018 THSYN_RS28665 3f16ebb03237f9ea02ccd5494e185350 966 SUPERFAMILY SSF52518 144 548 1.72E-84 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Pfam PF13188 PAS domain 632 677 7.0E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Gene3D G3DSA:3.30.450.20 357 493 5.7E-24 T 29-03-2018 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SMART SM00065 751 902 5.7E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SMART SM00448 1296 1410 5.4E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Gene3D G3DSA:3.30.565.10 1108 1276 4.5E-49 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Gene3D G3DSA:3.40.50.2300 1286 1413 2.7E-36 T 29-03-2018 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Gene3D G3DSA:3.40.190.10 142 323 9.7E-27 T 29-03-2018 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Gene3D G3DSA:3.40.190.10 32 134 8.6E-12 T 29-03-2018 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Pfam PF09084 NMT1/THI5 like 45 250 8.1E-51 T 29-03-2018 IPR015168 SsuA/THI5-like THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SUPERFAMILY SSF52172 1296 1415 3.98E-36 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Pfam PF01627 Hpt domain 1459 1526 5.1E-8 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Gene3D G3DSA:1.20.120.160 1414 1539 1.1E-14 T 29-03-2018 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SUPERFAMILY SSF55874 1093 1265 3.93E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SMART SM00091 375 439 7.7E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SMART SM00091 632 700 0.0024 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SMART SM00091 906 973 1.1E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SMART SM00091 503 570 7.5E-4 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Pfam PF13426 PAS domain 920 1018 4.1E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Pfam PF13426 PAS domain 385 490 2.0E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Pfam PF00072 Response regulator receiver domain 1299 1410 5.2E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SMART SM00388 1039 1104 9.8E-25 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 371 498 3.0E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 499 627 1.9E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 903 1026 1.5E-20 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 628 675 2.3E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SUPERFAMILY SSF55785 891 1017 2.42E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Gene3D G3DSA:3.30.450.20 622 689 7.0E-16 T 29-03-2018 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SUPERFAMILY SSF47226 1438 1537 2.22E-19 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SUPERFAMILY SSF47226 1393 1406 2.22E-19 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SMART SM00387 1151 1267 8.0E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SUPERFAMILY SSF55785 488 618 1.4E-20 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1251 1264 5.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1192 1206 5.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1227 1245 5.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1210 1220 5.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SUPERFAMILY SSF55785 616 680 8.2E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SUPERFAMILY SSF47384 1024 1105 6.67E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1151 1266 1.2E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Gene3D G3DSA:3.30.450.20 494 621 1.8E-27 T 29-03-2018 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Gene3D G3DSA:3.30.450.20 896 1038 2.3E-27 T 29-03-2018 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Pfam PF13185 GAF domain 750 891 2.6E-25 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1039 1103 3.0E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SMART SM00086 578 620 1.7 T 29-03-2018 IPR001610 PAC motif THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SMART SM00086 451 491 15.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SMART SM00086 979 1019 0.0025 T 29-03-2018 IPR001610 PAC motif THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SUPERFAMILY SSF55785 362 489 7.5E-19 T 29-03-2018 IPR000014 PAS domain THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Gene3D G3DSA:3.30.450.20 690 730 0.011 T 29-03-2018 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SUPERFAMILY SSF53850 36 315 1.93E-30 T 29-03-2018 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Gene3D G3DSA:3.30.450.40 731 895 1.1E-19 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 SUPERFAMILY SSF55781 753 905 1.05E-16 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Pfam PF00989 PAS fold 504 617 1.2E-8 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS10085 d1ce85d59f34fe1c69c22e36beb4dd4d 1641 Gene3D G3DSA:1.10.287.130 1039 1100 2.3E-20 T 29-03-2018 THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Gene3D G3DSA:2.130.10.10 180 518 1.9E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 543 583 6.4E-10 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 842 874 1.4E-4 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 627 662 1.6E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 606 647 4.6E-4 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 293 332 3.1E-8 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 585 623 1.5E-7 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 933 963 4.5E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 648 683 3.5E-7 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 737 775 3.1E-4 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 779 819 2.6E-6 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 758 799 8.1E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 416 456 1.0E-7 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 800 837 6.6E-6 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 250 289 3.5E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 893 920 1.0E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1117 1149 4.9E-4 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 463 495 4.3E-8 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 501 537 2.2E-7 T 29-03-2018 IPR006530 YD repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1223 1304 2.2E-18 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 SUPERFAMILY SSF101898 746 856 1.05E-5 T 29-03-2018 THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 SUPERFAMILY SSF101898 530 680 1.05E-5 T 29-03-2018 THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 627 662 7.2E-5 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 800 835 2.6E-9 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 653 684 2.8E-6 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 293 327 1.3E-8 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 463 495 7.2E-10 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 585 618 7.0E-10 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 933 967 4.8E-8 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 423 449 5.0E-6 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 893 926 6.2E-6 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 249 285 1.8E-5 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 543 579 1.1E-10 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 501 537 1.5E-9 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 758 792 1.2E-7 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF05593 RHS Repeat 842 873 3.3E-7 T 29-03-2018 IPR031325 RHS repeat THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Gene3D G3DSA:2.130.10.10 536 1281 3.5E-5 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS32220 80c175101b7a910671a5a59a2c40a3f2 1455 Pfam PF03527 RHS protein 1196 1230 3.3E-9 T 29-03-2018 IPR001826 RHS protein THSYN_RS18700 0b8daa7ed05d8654f227bdfcf0b549f5 431 Gene3D G3DSA:2.40.50.100 93 150 8.5E-17 T 29-03-2018 THSYN_RS18700 0b8daa7ed05d8654f227bdfcf0b549f5 431 SUPERFAMILY SSF111369 85 320 5.62E-55 T 29-03-2018 THSYN_RS18700 0b8daa7ed05d8654f227bdfcf0b549f5 431 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 70 397 8.3E-73 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS18700 0b8daa7ed05d8654f227bdfcf0b549f5 431 Gene3D G3DSA:2.40.50.100 200 398 5.9E-5 T 29-03-2018 THSYN_RS18700 0b8daa7ed05d8654f227bdfcf0b549f5 431 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 87 316 2.1E-15 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS18700 0b8daa7ed05d8654f227bdfcf0b549f5 431 Gene3D G3DSA:1.10.287.470 151 199 1.3E-9 T 29-03-2018 THSYN_RS32040 b7cb456ed21c242b9f489def0ebeb74b 329 Hamap MF_00486 Methenyltetrahydromethanopterin cyclohydrolase [mch]. 1 329 141.986 T 29-03-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 THSYN_RS32040 b7cb456ed21c242b9f489def0ebeb74b 329 TIGRFAM TIGR03120 one_C_mch: methenyltetrahydromethanopterin cyclohydrolase 7 326 3.9E-119 T 29-03-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 THSYN_RS32040 b7cb456ed21c242b9f489def0ebeb74b 329 Gene3D G3DSA:3.10.340.11 7 62 7.6E-8 T 29-03-2018 THSYN_RS32040 b7cb456ed21c242b9f489def0ebeb74b 329 Gene3D G3DSA:3.30.1030.10 63 132 5.9E-11 T 29-03-2018 THSYN_RS32040 b7cb456ed21c242b9f489def0ebeb74b 329 Gene3D G3DSA:3.30.1030.10 133 327 1.5E-81 T 29-03-2018 THSYN_RS32040 b7cb456ed21c242b9f489def0ebeb74b 329 SUPERFAMILY SSF56199 6 326 1.06E-119 T 29-03-2018 THSYN_RS32040 b7cb456ed21c242b9f489def0ebeb74b 329 Pfam PF02289 Cyclohydrolase (MCH) 7 325 8.5E-128 T 29-03-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 THSYN_RS06965 3f3ff88b7301cf8794dfdb0aaf127117 121 TIGRFAM TIGR01841 phasin: phasin family protein 32 113 4.0E-8 T 29-03-2018 IPR010127 Phasin, subfamily 1 THSYN_RS06965 3f3ff88b7301cf8794dfdb0aaf127117 121 Pfam PF09361 Phasin protein 9 104 3.6E-14 T 29-03-2018 IPR018968 Phasin THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 Gene3D G3DSA:3.30.450.40 217 384 2.3E-17 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SUPERFAMILY SSF55874 761 911 3.01E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 Gene3D G3DSA:3.30.450.20 73 216 2.0E-25 T 29-03-2018 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 Gene3D G3DSA:3.30.450.20 525 665 3.5E-18 T 29-03-2018 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 Gene3D G3DSA:3.30.565.10 764 916 1.0E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 PRINTS PR00344 Bacterial sensor protein C-terminal signature 897 910 1.3E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 PRINTS PR00344 Bacterial sensor protein C-terminal signature 862 872 1.3E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 PRINTS PR00344 Bacterial sensor protein C-terminal signature 844 858 1.3E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 PRINTS PR00344 Bacterial sensor protein C-terminal signature 873 891 1.3E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 809 911 4.3E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SMART SM00387 803 913 2.3E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SUPERFAMILY SSF55785 378 511 8.2E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 Gene3D G3DSA:3.30.450.20 385 524 1.6E-25 T 29-03-2018 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 Pfam PF00512 His Kinase A (phospho-acceptor) domain 694 762 9.4E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SMART SM00091 391 461 0.0011 T 29-03-2018 IPR000014 PAS domain THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SMART SM00091 103 170 3.0E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SMART SM00065 241 387 2.6E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 Pfam PF01590 GAF domain 254 377 2.4E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 Pfam PF08448 PAS fold 397 515 4.2E-10 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SUPERFAMILY SSF47384 688 762 9.61E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 Pfam PF13426 PAS domain 120 218 1.0E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SUPERFAMILY SSF55785 91 217 2.79E-20 T 29-03-2018 IPR000014 PAS domain THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 Pfam PF08447 PAS fold 557 639 5.9E-6 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 585 653 1.6E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 100 221 1.1E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SUPERFAMILY SSF55781 248 390 7.2E-16 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SUPERFAMILY SSF55785 542 649 7.78E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SMART SM00086 605 646 4.7E-4 T 29-03-2018 IPR001610 PAC motif THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SMART SM00086 177 219 3.6E-5 T 29-03-2018 IPR001610 PAC motif THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SMART SM00086 470 513 0.016 T 29-03-2018 IPR001610 PAC motif THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 SMART SM00388 693 763 1.4E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS02005 d2348063e81da0f9ef2bb2d62d9c6159 916 Gene3D G3DSA:1.10.287.130 666 759 6.3E-5 T 29-03-2018 THSYN_RS10650 44f1f35ef48bad9c52e287ff1f9c41e8 357 Pfam PF13527 Acetyltransferase (GNAT) domain 3 92 2.8E-6 T 29-03-2018 THSYN_RS10650 44f1f35ef48bad9c52e287ff1f9c41e8 357 SUPERFAMILY SSF55729 1 169 4.89E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS10650 44f1f35ef48bad9c52e287ff1f9c41e8 357 SUPERFAMILY SSF55729 208 290 4.89E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS10650 44f1f35ef48bad9c52e287ff1f9c41e8 357 Gene3D G3DSA:3.40.630.30 146 318 8.2E-6 T 29-03-2018 THSYN_RS10650 44f1f35ef48bad9c52e287ff1f9c41e8 357 Gene3D G3DSA:3.40.630.30 1 98 4.9E-10 T 29-03-2018 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 Pfam PF03477 ATP cone domain 43 139 2.8E-18 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 761 783 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 313 914 1.2E-120 T 29-03-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 SUPERFAMILY SSF51998 852 920 3.36E-181 T 29-03-2018 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 SUPERFAMILY SSF51998 382 821 3.36E-181 T 29-03-2018 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 Gene3D G3DSA:3.20.70.20 287 924 7.2E-215 T 29-03-2018 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 PRINTS PR01183 Ribonucleotide reductase large chain signature 696 719 9.4E-45 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 PRINTS PR01183 Ribonucleotide reductase large chain signature 630 653 9.4E-45 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 PRINTS PR01183 Ribonucleotide reductase large chain signature 772 799 9.4E-45 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 PRINTS PR01183 Ribonucleotide reductase large chain signature 668 690 9.4E-45 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 PRINTS PR01183 Ribonucleotide reductase large chain signature 593 604 9.4E-45 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 PRINTS PR01183 Ribonucleotide reductase large chain signature 458 477 9.4E-45 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 SUPERFAMILY SSF48168 164 381 2.35E-59 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 305 377 2.0E-23 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 308 920 1.2E-215 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS20755 1aa6c92c20d43a35f732d4b91797a0a9 974 Pfam PF02867 Ribonucleotide reductase, barrel domain 383 917 3.5E-183 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 Pfam PF05746 DALR anticodon binding domain 469 589 1.4E-35 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 SUPERFAMILY SSF55190 5 111 1.15E-24 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 SMART SM01016 3 91 1.1E-36 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 Hamap MF_00123 Arginine--tRNA ligase [argS]. 3 589 25.929 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 Gene3D G3DSA:3.40.50.620 105 393 7.4E-51 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 Gene3D G3DSA:3.30.1360.70 1 104 2.1E-30 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 Gene3D G3DSA:1.10.730.10 434 589 3.8E-46 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 130 139 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 PRINTS PR01038 Arginyl-tRNA synthetase signature 159 172 1.8E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 PRINTS PR01038 Arginyl-tRNA synthetase signature 337 358 1.8E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 PRINTS PR01038 Arginyl-tRNA synthetase signature 120 135 1.8E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 PRINTS PR01038 Arginyl-tRNA synthetase signature 135 151 1.8E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 4 91 7.6E-24 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 Pfam PF00750 tRNA synthetases class I (R) 100 177 3.0E-10 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 Pfam PF00750 tRNA synthetases class I (R) 299 431 1.7E-8 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 SUPERFAMILY SSF52374 115 479 8.89E-87 T 29-03-2018 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 24 589 3.0E-132 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 SUPERFAMILY SSF47323 462 589 3.99E-36 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS11140 b1a22c3329b424f33fced18f3008051b 589 SMART SM00836 468 589 1.6E-56 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 THSYN_RS18155 5289d67ce5d5c2370cc68e1dafb8e810 279 Pfam PF12697 Alpha/beta hydrolase family 29 272 2.8E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS18155 5289d67ce5d5c2370cc68e1dafb8e810 279 SUPERFAMILY SSF53474 3 272 3.24E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS18155 5289d67ce5d5c2370cc68e1dafb8e810 279 Gene3D G3DSA:3.40.50.1820 11 279 1.9E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS14455 6163eef288805f64c8f815f99c1a0812 487 Pfam PF01189 16S rRNA methyltransferase RsmB/F 113 319 1.6E-48 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS14455 6163eef288805f64c8f815f99c1a0812 487 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 95 109 5.4E-27 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS14455 6163eef288805f64c8f815f99c1a0812 487 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 190 202 5.4E-27 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS14455 6163eef288805f64c8f815f99c1a0812 487 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 124 134 5.4E-27 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS14455 6163eef288805f64c8f815f99c1a0812 487 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 240 256 5.4E-27 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS14455 6163eef288805f64c8f815f99c1a0812 487 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 304 321 5.4E-27 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS14455 6163eef288805f64c8f815f99c1a0812 487 SUPERFAMILY SSF53335 29 321 1.81E-69 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS14455 6163eef288805f64c8f815f99c1a0812 487 Gene3D G3DSA:3.30.70.1170 48 102 6.7E-6 T 29-03-2018 THSYN_RS14455 6163eef288805f64c8f815f99c1a0812 487 Gene3D G3DSA:3.40.50.150 104 330 5.5E-69 T 29-03-2018 THSYN_RS14455 6163eef288805f64c8f815f99c1a0812 487 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 27 106 2.5E-7 T 29-03-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 14 391 9.8E-119 T 29-03-2018 IPR017687 Outer membrane protein assembly factor BamB THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 SMART SM00564 155 187 2.0E-4 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 SMART SM00564 201 232 130.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 SMART SM00564 331 362 280.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 SMART SM00564 115 146 3.5E-4 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 SMART SM00564 75 106 0.0015 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 SMART SM00564 252 283 0.55 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 SUPERFAMILY SSF50998 47 385 6.67E-71 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 Gene3D G3DSA:2.140.10.10 236 440 5.4E-16 T 29-03-2018 THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 9 393 34.646 T 29-03-2018 IPR017687 Outer membrane protein assembly factor BamB THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 Pfam PF01011 PQQ enzyme repeat 80 112 5.7E-5 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 Pfam PF13360 PQQ-like domain 331 394 2.5E-4 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 Pfam PF13360 PQQ-like domain 130 320 4.1E-35 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat THSYN_RS07620 42b4adf5bbc135ca0a39cf0f76dcfef4 460 Gene3D G3DSA:2.140.10.10 6 194 1.9E-28 T 29-03-2018 THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 422 431 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 SMART SM00382 230 373 1.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 Pfam PF02954 Bacterial regulatory protein, Fis family 500 534 7.8E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 SMART SM00065 39 187 1.1E-24 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 Pfam PF00158 Sigma-54 interaction domain 210 376 1.1E-72 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 SUPERFAMILY SSF52540 209 450 4.54E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 519 539 8.7E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 502 519 8.7E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 Gene3D G3DSA:3.30.450.40 16 203 5.5E-25 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 234 247 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 Gene3D G3DSA:1.10.8.60 383 453 2.1E-22 T 29-03-2018 THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 296 311 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 Gene3D G3DSA:3.40.50.300 206 382 1.0E-29 T 29-03-2018 THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 TIGRFAM TIGR01817 nifA: Nif-specific regulatory protein 22 543 1.9E-212 T 29-03-2018 IPR010113 Nif-specific regulatory protein GO:0003700|GO:0006355|GO:0009399 THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 Pfam PF13185 GAF domain 38 177 2.7E-13 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 SUPERFAMILY SSF55781 18 177 3.05E-22 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS24760 022af22531773a31a79a19237026bfb0 543 Gene3D G3DSA:1.10.10.60 468 534 3.3E-7 T 29-03-2018 THSYN_RS22125 83c7ecfa80764ac828a66f2fa6dd82de 224 Pfam PF01730 UreF 38 182 9.8E-34 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 THSYN_RS22125 83c7ecfa80764ac828a66f2fa6dd82de 224 PIRSF PIRSF009467 4 224 4.2E-61 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 THSYN_RS22125 83c7ecfa80764ac828a66f2fa6dd82de 224 Hamap MF_01385 Urease accessory protein UreF [ureF]. 6 224 31.796 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 THSYN_RS25130 f2bfaa796a527047bf1474aa43fd0130 338 Pfam PF00535 Glycosyl transferase family 2 19 123 2.4E-16 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS25130 f2bfaa796a527047bf1474aa43fd0130 338 SUPERFAMILY SSF53448 11 245 2.04E-42 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS25130 f2bfaa796a527047bf1474aa43fd0130 338 Gene3D G3DSA:3.90.550.10 2 290 1.9E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS28870 4e6feba3c6cb01e18f131f5fdfe32785 437 Pfam PF02481 DNA recombination-mediator protein A 96 298 3.0E-36 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 THSYN_RS28870 4e6feba3c6cb01e18f131f5fdfe32785 437 Gene3D G3DSA:3.40.50.450 134 298 1.8E-23 T 29-03-2018 THSYN_RS28870 4e6feba3c6cb01e18f131f5fdfe32785 437 Gene3D G3DSA:1.10.10.10 357 429 3.3E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS28870 4e6feba3c6cb01e18f131f5fdfe32785 437 Pfam PF13463 Winged helix DNA-binding domain 378 425 8.5E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THSYN_RS28870 4e6feba3c6cb01e18f131f5fdfe32785 437 SUPERFAMILY SSF102405 106 298 8.85E-27 T 29-03-2018 THSYN_RS00375 c9689cd40b1c7652267974b6b8a30d31 235 SMART SM00895 87 214 4.2E-24 T 29-03-2018 IPR011711 GntR, C-terminal THSYN_RS00375 c9689cd40b1c7652267974b6b8a30d31 235 Gene3D G3DSA:1.20.120.530 80 232 8.4E-32 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal THSYN_RS00375 c9689cd40b1c7652267974b6b8a30d31 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 77 4.4E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THSYN_RS00375 c9689cd40b1c7652267974b6b8a30d31 235 SMART SM00345 19 77 1.4E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THSYN_RS00375 c9689cd40b1c7652267974b6b8a30d31 235 Pfam PF07729 FCD domain 87 213 2.3E-24 T 29-03-2018 IPR011711 GntR, C-terminal THSYN_RS00375 c9689cd40b1c7652267974b6b8a30d31 235 Gene3D G3DSA:1.10.10.10 1 79 7.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS00375 c9689cd40b1c7652267974b6b8a30d31 235 SUPERFAMILY SSF48008 83 220 1.73E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal THSYN_RS00375 c9689cd40b1c7652267974b6b8a30d31 235 SUPERFAMILY SSF46785 12 106 1.98E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 321 36.811 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 Gene3D G3DSA:1.10.1040.10 184 329 8.8E-54 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 187 208 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 179 317 2.8E-51 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 197 221 4.4E-44 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 57 84 4.4E-44 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 4.4E-44 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 172 196 4.4E-44 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 132 152 4.4E-44 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 237 254 4.4E-44 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 PIRSF PIRSF000114 3 331 4.0E-98 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 SUPERFAMILY SSF51735 4 177 1.58E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 SUPERFAMILY SSF48179 178 330 2.38E-55 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 159 1.5E-44 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 THSYN_RS00115 685db9c49758d9713164d8c88e8ad7bd 332 Gene3D G3DSA:3.40.50.720 2 183 4.6E-35 T 29-03-2018 THSYN_RS11310 1c3a8186f7578d5d5b905fcd5401ee4f 611 SUPERFAMILY SSF82649 458 589 8.89E-37 T 29-03-2018 THSYN_RS11310 1c3a8186f7578d5d5b905fcd5401ee4f 611 Gene3D G3DSA:3.40.640.10 46 294 2.0E-60 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS11310 1c3a8186f7578d5d5b905fcd5401ee4f 611 Gene3D G3DSA:3.90.1010.10 444 589 8.1E-40 T 29-03-2018 THSYN_RS11310 1c3a8186f7578d5d5b905fcd5401ee4f 611 SUPERFAMILY SSF53383 16 417 2.48E-121 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS11310 1c3a8186f7578d5d5b905fcd5401ee4f 611 Gene3D G3DSA:3.90.1150.10 295 415 5.1E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS11310 1c3a8186f7578d5d5b905fcd5401ee4f 611 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 19 415 9.6E-162 T 29-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 THSYN_RS11310 1c3a8186f7578d5d5b905fcd5401ee4f 611 Pfam PF02657 Fe-S metabolism associated domain 463 584 3.1E-38 T 29-03-2018 IPR003808 Fe-S metabolism associated domain, SufE-like THSYN_RS11310 1c3a8186f7578d5d5b905fcd5401ee4f 611 Pfam PF00266 Aminotransferase class-V 37 408 1.2E-137 T 29-03-2018 IPR000192 Aminotransferase class V domain THSYN_RS01465 cb4b576578e02343dda7e2567756215a 1655 Gene3D G3DSA:1.20.58.280 1395 1490 3.4E-4 T 29-03-2018 THSYN_RS01465 cb4b576578e02343dda7e2567756215a 1655 Gene3D G3DSA:1.20.58.280 1293 1385 7.1E-4 T 29-03-2018 THSYN_RS01465 cb4b576578e02343dda7e2567756215a 1655 Gene3D G3DSA:1.20.58.280 1074 1172 2.7E-4 T 29-03-2018 THSYN_RS01465 cb4b576578e02343dda7e2567756215a 1655 SUPERFAMILY SSF48452 1354 1536 1.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01465 cb4b576578e02343dda7e2567756215a 1655 Gene3D G3DSA:1.25.40.10 926 1071 0.0034 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01465 cb4b576578e02343dda7e2567756215a 1655 Gene3D G3DSA:1.20.1250.10 1173 1281 0.059 T 29-03-2018 THSYN_RS01465 cb4b576578e02343dda7e2567756215a 1655 Gene3D G3DSA:1.25.40.10 1491 1639 0.013 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01465 cb4b576578e02343dda7e2567756215a 1655 SUPERFAMILY SSF48452 1266 1415 9.49E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08540 626d5dfa14f6d374e3657165aee6f029 92 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 8 76 8.0E-14 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS08540 626d5dfa14f6d374e3657165aee6f029 92 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 7 82 1.1E-6 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS08540 626d5dfa14f6d374e3657165aee6f029 92 Gene3D G3DSA:1.10.1220.10 5 46 1.3E-9 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS08540 626d5dfa14f6d374e3657165aee6f029 92 SUPERFAMILY SSF47598 3 46 7.78E-9 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS02760 9320b5092cf66bbf1e42884be0b064ee 305 Gene3D G3DSA:3.40.50.300 1 220 1.2E-57 T 29-03-2018 THSYN_RS02760 9320b5092cf66bbf1e42884be0b064ee 305 Pfam PF00005 ABC transporter 21 163 2.9E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS02760 9320b5092cf66bbf1e42884be0b064ee 305 SMART SM00382 29 233 3.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS02760 9320b5092cf66bbf1e42884be0b064ee 305 SUPERFAMILY SSF52540 4 214 9.53E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 Gene3D G3DSA:2.80.10.50 1135 1164 0.0025 T 29-03-2018 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 Gene3D G3DSA:3.40.50.300 198 396 4.4E-9 T 29-03-2018 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 Gene3D G3DSA:2.130.10.10 791 1134 4.7E-30 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 Gene3D G3DSA:2.120.10.30 1549 1630 1.2E-6 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 Pfam PF13191 AAA ATPase domain 216 386 1.6E-11 T 29-03-2018 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1504 1518 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 Pfam PF00400 WD domain, G-beta repeat 1276 1308 4.7E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 Pfam PF00400 WD domain, G-beta repeat 1521 1557 3.8E-6 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 Pfam PF00400 WD domain, G-beta repeat 995 1022 0.1 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 Gene3D G3DSA:1.10.10.670 1165 1223 3.0E-11 T 29-03-2018 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 Gene3D G3DSA:2.40.50.140 1504 1548 2.9E-14 T 29-03-2018 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SUPERFAMILY SSF52540 341 459 8.1E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SUPERFAMILY SSF52540 215 287 8.1E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 Gene3D G3DSA:2.130.10.10 1224 1321 4.8E-16 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SMART SM00320 1339 1380 11.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SMART SM00320 1572 1611 21.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SMART SM00320 1213 1260 4.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SMART SM00320 1027 1069 98.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SMART SM00320 985 1024 6.9E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SMART SM00320 1269 1308 3.8E-8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SMART SM00320 1170 1209 0.0041 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SMART SM00320 1519 1558 6.1E-8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SMART SM00320 1478 1517 0.0051 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SMART SM00320 1434 1473 5.9E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SMART SM00320 1122 1167 7.9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SMART SM00320 1084 1120 0.018 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SUPERFAMILY SSF50978 1340 1561 3.36E-50 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SUPERFAMILY SSF50978 1244 1313 3.36E-50 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1295 1309 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 Gene3D G3DSA:2.130.10.10 1339 1503 4.1E-27 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SUPERFAMILY SSF50998 872 890 2.67E-49 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SUPERFAMILY SSF50998 1347 1382 2.67E-49 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS27070 ce21955cac084905cce4cfb71e52e2f4 1656 SUPERFAMILY SSF50998 934 1312 2.67E-49 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS08780 d4b5b6b2bef99ab94d4ab29d19b464e0 248 Pfam PF01695 IstB-like ATP binding protein 56 232 1.1E-58 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 THSYN_RS08780 d4b5b6b2bef99ab94d4ab29d19b464e0 248 SMART SM00382 100 236 0.0043 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS08780 d4b5b6b2bef99ab94d4ab29d19b464e0 248 SUPERFAMILY SSF52540 68 229 1.23E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08780 d4b5b6b2bef99ab94d4ab29d19b464e0 248 Gene3D G3DSA:3.40.50.300 42 235 6.3E-16 T 29-03-2018 THSYN_RS08780 d4b5b6b2bef99ab94d4ab29d19b464e0 248 PIRSF PIRSF003073 1 248 2.0E-85 T 29-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein THSYN_RS27585 d4b5b6b2bef99ab94d4ab29d19b464e0 248 Pfam PF01695 IstB-like ATP binding protein 56 232 1.1E-58 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 THSYN_RS27585 d4b5b6b2bef99ab94d4ab29d19b464e0 248 SMART SM00382 100 236 0.0043 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS27585 d4b5b6b2bef99ab94d4ab29d19b464e0 248 SUPERFAMILY SSF52540 68 229 1.23E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27585 d4b5b6b2bef99ab94d4ab29d19b464e0 248 Gene3D G3DSA:3.40.50.300 42 235 6.3E-16 T 29-03-2018 THSYN_RS27585 d4b5b6b2bef99ab94d4ab29d19b464e0 248 PIRSF PIRSF003073 1 248 2.0E-85 T 29-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein THSYN_RS06735 d4b5b6b2bef99ab94d4ab29d19b464e0 248 Pfam PF01695 IstB-like ATP binding protein 56 232 1.1E-58 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 THSYN_RS06735 d4b5b6b2bef99ab94d4ab29d19b464e0 248 SMART SM00382 100 236 0.0043 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS06735 d4b5b6b2bef99ab94d4ab29d19b464e0 248 SUPERFAMILY SSF52540 68 229 1.23E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06735 d4b5b6b2bef99ab94d4ab29d19b464e0 248 Gene3D G3DSA:3.40.50.300 42 235 6.3E-16 T 29-03-2018 THSYN_RS06735 d4b5b6b2bef99ab94d4ab29d19b464e0 248 PIRSF PIRSF003073 1 248 2.0E-85 T 29-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein THSYN_RS28335 5ca911bb0af2acf75ef87095f6c030cb 84 SUPERFAMILY SSF159127 2 75 1.96E-21 T 29-03-2018 THSYN_RS28335 5ca911bb0af2acf75ef87095f6c030cb 84 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 9.1E-11 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS28335 5ca911bb0af2acf75ef87095f6c030cb 84 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 9.1E-11 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS28335 5ca911bb0af2acf75ef87095f6c030cb 84 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 40 56 9.1E-11 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS28335 5ca911bb0af2acf75ef87095f6c030cb 84 Pfam PF01455 HupF/HypC family 2 66 5.5E-21 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS28335 5ca911bb0af2acf75ef87095f6c030cb 84 Gene3D G3DSA:2.40.50.140 3 51 7.6E-4 T 29-03-2018 THSYN_RS28335 5ca911bb0af2acf75ef87095f6c030cb 84 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 2 78 2.4E-23 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS26310 58902bda99360ea5cf886b742e8f2959 581 PRINTS PR00775 90kDa heat shock protein signature 178 200 9.1E-13 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal THSYN_RS26310 58902bda99360ea5cf886b742e8f2959 581 PRINTS PR00775 90kDa heat shock protein signature 86 108 9.1E-13 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal THSYN_RS26310 58902bda99360ea5cf886b742e8f2959 581 PRINTS PR00775 90kDa heat shock protein signature 131 148 9.1E-13 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal THSYN_RS26310 58902bda99360ea5cf886b742e8f2959 581 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 89 201 4.1E-9 T 29-03-2018 THSYN_RS26310 58902bda99360ea5cf886b742e8f2959 581 Gene3D G3DSA:3.30.565.10 66 295 5.2E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS26310 58902bda99360ea5cf886b742e8f2959 581 SUPERFAMILY SSF55874 76 205 7.33E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS21255 bb685c2c0de1fafeb7e2791b29f95271 286 Gene3D G3DSA:3.40.50.300 39 192 1.3E-10 T 29-03-2018 THSYN_RS21255 bb685c2c0de1fafeb7e2791b29f95271 286 Pfam PF05673 Protein of unknown function (DUF815) 34 284 5.4E-101 T 29-03-2018 IPR008533 Domain of unknown function DUF815 THSYN_RS21255 bb685c2c0de1fafeb7e2791b29f95271 286 SUPERFAMILY SSF52540 10 188 5.05E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17690 2967be46c0dad6222f8a2a5d1c667ad7 153 Pfam PF01724 Domain of unknown function DUF29 9 136 2.0E-47 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS20980 0a8129126a32e42c31656869b885043b 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.6E-16 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20980 0a8129126a32e42c31656869b885043b 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.6E-16 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20980 0a8129126a32e42c31656869b885043b 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.6E-16 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20980 0a8129126a32e42c31656869b885043b 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.6E-16 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20980 0a8129126a32e42c31656869b885043b 71 Pfam PF01165 Ribosomal protein S21 3 56 1.0E-21 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20980 0a8129126a32e42c31656869b885043b 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.252 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20980 0a8129126a32e42c31656869b885043b 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 3.5E-24 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20980 0a8129126a32e42c31656869b885043b 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 44 3.0E-9 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20980 0a8129126a32e42c31656869b885043b 71 Gene3D G3DSA:1.20.5.1150 16 52 3.6E-17 T 29-03-2018 THSYN_RS00940 ff729ef1676a5a76bf9eb701aea7a16c 1171 SUPERFAMILY SSF52540 22 90 5.32E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00940 ff729ef1676a5a76bf9eb701aea7a16c 1171 SUPERFAMILY SSF52540 275 303 5.32E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00940 ff729ef1676a5a76bf9eb701aea7a16c 1171 SUPERFAMILY SSF52540 143 241 5.32E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00940 ff729ef1676a5a76bf9eb701aea7a16c 1171 Gene3D G3DSA:3.40.50.300 54 324 6.0E-9 T 29-03-2018 THSYN_RS32290 faf2ba141d50f2d47f4144ac01d58637 531 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 344 509 1.5E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS32290 faf2ba141d50f2d47f4144ac01d58637 531 Gene3D G3DSA:1.10.3720.10 316 525 1.9E-25 T 29-03-2018 THSYN_RS32290 faf2ba141d50f2d47f4144ac01d58637 531 SUPERFAMILY SSF161098 4 261 8.11E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS32290 faf2ba141d50f2d47f4144ac01d58637 531 Gene3D G3DSA:1.10.3720.10 5 268 1.1E-26 T 29-03-2018 THSYN_RS32290 faf2ba141d50f2d47f4144ac01d58637 531 SUPERFAMILY SSF161098 284 519 3.01E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 PRINTS PR00315 GTP-binding elongation factor signature 129 138 8.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 PRINTS PR00315 GTP-binding elongation factor signature 77 87 8.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 PRINTS PR00315 GTP-binding elongation factor signature 52 60 8.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 PRINTS PR00315 GTP-binding elongation factor signature 93 104 8.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 PRINTS PR00315 GTP-binding elongation factor signature 9 22 8.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 45 60 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 Gene3D G3DSA:3.30.70.240 392 551 5.9E-27 T 29-03-2018 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 SMART SM00838 403 488 0.0023 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 Pfam PF00009 Elongation factor Tu GTP binding domain 6 184 3.1E-50 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 Pfam PF00679 Elongation factor G C-terminus 401 486 6.8E-20 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 SUPERFAMILY SSF52540 1 231 3.55E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 TIGRFAM TIGR01393 lepA: elongation factor 4 6 596 2.2E-291 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 Hamap MF_00071 Elongation factor 4 [lepA]. 1 599 298.017 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 Gene3D G3DSA:2.40.30.10 191 288 4.1E-22 T 29-03-2018 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 176 2.9E-19 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 Gene3D G3DSA:3.40.50.300 3 188 5.4E-35 T 29-03-2018 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 Pfam PF06421 GTP-binding protein LepA C-terminus 489 595 1.1E-48 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 SUPERFAMILY SSF54980 401 495 9.59E-24 T 29-03-2018 IPR035647 EF-G domain III/V-like THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 SUPERFAMILY SSF54980 294 372 5.4E-18 T 29-03-2018 IPR035647 EF-G domain III/V-like THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 Pfam PF03144 Elongation factor Tu domain 2 208 278 2.8E-8 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THSYN_RS24075 9d105bce544ea49a08405ad44edc7710 600 Gene3D G3DSA:3.30.70.870 289 369 1.3E-25 T 29-03-2018 THSYN_RS13870 7fee7c92c75cb39a706540da7c032420 724 SUPERFAMILY SSF47384 488 560 1.92E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS13870 7fee7c92c75cb39a706540da7c032420 724 Gene3D G3DSA:1.10.287.130 488 557 1.8E-16 T 29-03-2018 THSYN_RS13870 7fee7c92c75cb39a706540da7c032420 724 PRINTS PR00344 Bacterial sensor protein C-terminal signature 704 717 6.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS13870 7fee7c92c75cb39a706540da7c032420 724 PRINTS PR00344 Bacterial sensor protein C-terminal signature 681 699 6.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS13870 7fee7c92c75cb39a706540da7c032420 724 PRINTS PR00344 Bacterial sensor protein C-terminal signature 646 660 6.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS13870 7fee7c92c75cb39a706540da7c032420 724 PRINTS PR00344 Bacterial sensor protein C-terminal signature 664 674 6.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS13870 7fee7c92c75cb39a706540da7c032420 724 SUPERFAMILY SSF55874 551 717 1.96E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS13870 7fee7c92c75cb39a706540da7c032420 724 SMART SM00387 606 720 1.8E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS13870 7fee7c92c75cb39a706540da7c032420 724 Gene3D G3DSA:3.30.565.10 565 721 1.5E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS13870 7fee7c92c75cb39a706540da7c032420 724 Pfam PF00512 His Kinase A (phospho-acceptor) domain 496 559 4.3E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS13870 7fee7c92c75cb39a706540da7c032420 724 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 607 718 5.7E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS13870 7fee7c92c75cb39a706540da7c032420 724 SMART SM00388 495 561 6.1E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS29780 2d548c02145e7f94436cd88bf691ffa9 595 SUPERFAMILY SSF52091 467 578 8.63E-15 T 29-03-2018 IPR002645 STAS domain THSYN_RS29780 2d548c02145e7f94436cd88bf691ffa9 595 Pfam PF01740 STAS domain 467 576 1.5E-17 T 29-03-2018 IPR002645 STAS domain THSYN_RS29780 2d548c02145e7f94436cd88bf691ffa9 595 Pfam PF00916 Sulfate permease family 46 411 5.0E-80 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 THSYN_RS29780 2d548c02145e7f94436cd88bf691ffa9 595 Gene3D G3DSA:3.30.750.24 445 584 4.6E-28 T 29-03-2018 IPR002645 STAS domain THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 660 774 9.0E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 Gene3D G3DSA:1.20.120.160 956 1128 3.8E-16 T 29-03-2018 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 SMART SM00387 660 776 4.8E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 SUPERFAMILY SSF47384 535 614 1.92E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 Pfam PF00512 His Kinase A (phospho-acceptor) domain 548 613 2.5E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 PRINTS PR00344 Bacterial sensor protein C-terminal signature 736 754 1.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 PRINTS PR00344 Bacterial sensor protein C-terminal signature 701 715 1.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 PRINTS PR00344 Bacterial sensor protein C-terminal signature 760 773 1.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 Pfam PF01627 Hpt domain 975 1052 1.8E-10 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 SMART SM00388 548 613 9.5E-26 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 SMART SM01079 249 444 2.1E-43 T 29-03-2018 IPR006189 CHASE domain THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 Gene3D G3DSA:1.10.287.130 538 609 2.5E-20 T 29-03-2018 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 SUPERFAMILY SSF52172 802 921 1.99E-33 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 SUPERFAMILY SSF47226 900 912 5.5E-16 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 SUPERFAMILY SSF47226 954 1041 5.5E-16 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 Pfam PF00072 Response regulator receiver domain 804 916 9.1E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 SMART SM00448 801 916 9.5E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 SMART SM00073 964 1061 5.6E-10 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 SUPERFAMILY SSF55874 602 777 1.57E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 Gene3D G3DSA:3.40.50.2300 793 928 2.2E-34 T 29-03-2018 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 Pfam PF03924 CHASE domain 252 442 9.2E-39 T 29-03-2018 IPR006189 CHASE domain THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 Pfam PF05231 MASE1 6 189 5.5E-21 T 29-03-2018 IPR007895 MASE1 THSYN_RS01445 47eec02e2a0932c9e000a124a230a13c 1151 Gene3D G3DSA:3.30.565.10 617 784 1.5E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS03270 73c6c7b7146714690b10d8a8b21bb658 114 Gene3D G3DSA:3.30.429.10 1 114 2.5E-29 T 29-03-2018 THSYN_RS03270 73c6c7b7146714690b10d8a8b21bb658 114 ProDom PD004816 MACROPHAGE MIGRATION INHIBITORY FACTOR TAUTOMERASE MIF PHENYLPYRUVATE CYTOKINE RESPONSE INFLAMMATORY 20 114 4.0E-20 T 29-03-2018 IPR001398 Macrophage migration inhibitory factor THSYN_RS03270 73c6c7b7146714690b10d8a8b21bb658 114 SUPERFAMILY SSF55331 1 114 1.28E-30 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily THSYN_RS03270 73c6c7b7146714690b10d8a8b21bb658 114 Pfam PF01187 Macrophage migration inhibitory factor (MIF) 2 114 2.2E-20 T 29-03-2018 IPR001398 Macrophage migration inhibitory factor THSYN_RS12160 85113dbe7e1a6eadc3cfb5fdac6cd0e0 1382 Gene3D G3DSA:3.40.50.300 1205 1360 6.2E-39 T 29-03-2018 THSYN_RS12160 85113dbe7e1a6eadc3cfb5fdac6cd0e0 1382 SUPERFAMILY SSF52540 1131 1360 6.3E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12160 85113dbe7e1a6eadc3cfb5fdac6cd0e0 1382 Pfam PF00176 SNF2 family N-terminal domain 941 1200 1.1E-55 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THSYN_RS12160 85113dbe7e1a6eadc3cfb5fdac6cd0e0 1382 SMART SM00487 918 1101 2.0E-22 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS12160 85113dbe7e1a6eadc3cfb5fdac6cd0e0 1382 Pfam PF00271 Helicase conserved C-terminal domain 1212 1322 1.1E-20 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS12160 85113dbe7e1a6eadc3cfb5fdac6cd0e0 1382 Gene3D G3DSA:3.40.50.10810 923 1130 8.7E-47 T 29-03-2018 THSYN_RS12160 85113dbe7e1a6eadc3cfb5fdac6cd0e0 1382 SUPERFAMILY SSF52540 909 1129 4.75E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12160 85113dbe7e1a6eadc3cfb5fdac6cd0e0 1382 SMART SM00490 1240 1322 2.2E-23 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS23660 3f534e44292a8fd1fc1ff0969921f581 320 Gene3D G3DSA:3.20.20.80 15 309 4.2E-5 T 29-03-2018 THSYN_RS23660 3f534e44292a8fd1fc1ff0969921f581 320 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 312 3.3E-90 T 29-03-2018 IPR007296 Domain of unknown function DUF403 THSYN_RS21345 a61c25b6f158bc123c4e0b0d92605daf 393 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 8 368 7.0E-89 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 THSYN_RS21345 a61c25b6f158bc123c4e0b0d92605daf 393 Gene3D G3DSA:3.40.50.2000 4 222 2.2E-79 T 29-03-2018 THSYN_RS21345 a61c25b6f158bc123c4e0b0d92605daf 393 Gene3D G3DSA:3.40.50.2000 223 351 3.8E-27 T 29-03-2018 THSYN_RS21345 a61c25b6f158bc123c4e0b0d92605daf 393 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 29 367 6.9E-100 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 THSYN_RS21345 a61c25b6f158bc123c4e0b0d92605daf 393 SUPERFAMILY SSF53756 8 368 2.3E-103 T 29-03-2018 THSYN_RS28835 b359712668a3c107ed05fa35c1e6227f 113 Gene3D G3DSA:3.30.70.120 3 110 2.7E-40 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THSYN_RS28835 b359712668a3c107ed05fa35c1e6227f 113 SUPERFAMILY SSF54913 7 110 1.15E-38 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THSYN_RS28835 b359712668a3c107ed05fa35c1e6227f 113 Pfam PF03091 CutA1 divalent ion tolerance protein 11 106 4.5E-37 T 29-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 SUPERFAMILY SSF52540 2 192 2.59E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 SUPERFAMILY SSF50447 174 259 4.52E-19 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 Gene3D G3DSA:2.40.30.10 267 348 2.1E-15 T 29-03-2018 THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 1 627 3.3E-136 T 29-03-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 SUPERFAMILY SSF46785 581 627 5.44E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 Pfam PF09107 Elongation factor SelB, winged helix 583 626 2.3E-17 T 29-03-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 Pfam PF09106 Elongation factor SelB, winged helix 442 498 7.6E-16 T 29-03-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 Gene3D G3DSA:1.10.10.10 507 567 1.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 SUPERFAMILY SSF50465 267 363 1.53E-18 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 PRINTS PR00315 GTP-binding elongation factor signature 54 64 1.2E-5 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 PRINTS PR00315 GTP-binding elongation factor signature 2 15 1.2E-5 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 PRINTS PR00315 GTP-binding elongation factor signature 70 81 1.2E-5 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 PRINTS PR00315 GTP-binding elongation factor signature 107 116 1.2E-5 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 Pfam PF03144 Elongation factor Tu domain 2 191 255 2.3E-7 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 Pfam PF00009 Elongation factor Tu GTP binding domain 2 157 3.0E-26 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 Gene3D G3DSA:2.40.30.10 174 260 2.7E-21 T 29-03-2018 THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 Gene3D G3DSA:1.10.10.10 434 498 9.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 Gene3D G3DSA:1.10.10.10 570 628 6.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 SUPERFAMILY SSF46785 433 503 1.22E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 Gene3D G3DSA:3.40.50.300 1 168 2.4E-30 T 29-03-2018 THSYN_RS27520 8d843348c7efeb4a00ff401b4fca6db6 635 SUPERFAMILY SSF46785 514 568 7.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 6.7E-179 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 439 34.392 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 Pfam PF00448 SRP54-type protein, GTPase domain 100 296 3.4E-74 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 Gene3D G3DSA:1.20.120.140 211 310 8.4E-33 T 29-03-2018 THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 4.8E-21 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 SMART SM00962 100 296 1.7E-118 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 Gene3D G3DSA:1.10.260.30 328 432 6.4E-37 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 SUPERFAMILY SSF52540 42 353 6.07E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 Gene3D G3DSA:3.40.50.300 99 210 3.9E-18 T 29-03-2018 THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 SMART SM00963 1 86 8.1E-37 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 Gene3D G3DSA:1.20.120.140 1 91 4.0E-29 T 29-03-2018 THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 SMART SM00382 99 247 7.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 Pfam PF02978 Signal peptide binding domain 329 427 1.9E-32 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 THSYN_RS15920 f51aa813d0b018211be8d3fc90c92692 466 SUPERFAMILY SSF47446 298 431 5.49E-46 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 THSYN_RS19085 fab4b684a0568b5474d9b061e6f6a139 787 Hamap MF_01403 Probable phosphoketolase. 5 786 41.609 T 29-03-2018 IPR023962 Probable phosphoketolase THSYN_RS19085 fab4b684a0568b5474d9b061e6f6a139 787 Pfam PF09363 XFP C-terminal domain 583 784 7.3E-96 T 29-03-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 THSYN_RS19085 fab4b684a0568b5474d9b061e6f6a139 787 ProSitePatterns PS60003 Phosphoketolase signature 2. 157 175 - T 29-03-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 THSYN_RS19085 fab4b684a0568b5474d9b061e6f6a139 787 PIRSF PIRSF017245 1 786 0.0 T 29-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 THSYN_RS19085 fab4b684a0568b5474d9b061e6f6a139 787 SUPERFAMILY SSF52518 8 368 6.6E-78 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS19085 fab4b684a0568b5474d9b061e6f6a139 787 Gene3D G3DSA:3.40.50.970 1 377 2.4E-88 T 29-03-2018 THSYN_RS19085 fab4b684a0568b5474d9b061e6f6a139 787 Pfam PF09364 XFP N-terminal domain 9 383 2.4E-195 T 29-03-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal THSYN_RS19085 fab4b684a0568b5474d9b061e6f6a139 787 ProSitePatterns PS60002 Phosphoketolase signature 1. 144 150 - T 29-03-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 THSYN_RS19085 fab4b684a0568b5474d9b061e6f6a139 787 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 399 572 6.1E-89 T 29-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 THSYN_RS19085 fab4b684a0568b5474d9b061e6f6a139 787 Gene3D G3DSA:3.40.50.970 385 598 5.3E-35 T 29-03-2018 THSYN_RS19085 fab4b684a0568b5474d9b061e6f6a139 787 Gene3D G3DSA:3.40.50.920 603 786 1.7E-85 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS19085 fab4b684a0568b5474d9b061e6f6a139 787 SUPERFAMILY SSF52518 375 589 2.41E-26 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 Pfam PF08264 Anticodon-binding domain of tRNA 691 844 1.4E-23 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 646 8.2E-206 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 Gene3D G3DSA:3.40.50.620 47 203 4.1E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 848 1.4E-279 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 Gene3D G3DSA:3.90.740.10 204 393 7.2E-61 T 29-03-2018 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 Pfam PF06827 Zinc finger found in FPG and IleRS 905 931 4.2E-7 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 407 422 2.0E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 567 576 2.0E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 51 62 2.0E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 241 264 2.0E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 533 546 2.0E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 SUPERFAMILY SSF52374 409 653 1.18E-136 T 29-03-2018 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 SUPERFAMILY SSF52374 3 202 1.18E-136 T 29-03-2018 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 Gene3D G3DSA:3.40.50.620 394 645 1.7E-72 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 SUPERFAMILY SSF47323 658 934 4.49E-74 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 Gene3D G3DSA:3.30.2320.20 825 901 2.7E-21 T 29-03-2018 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 SUPERFAMILY SSF50677 204 409 2.22E-54 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 2 934 21.286 T 29-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 THSYN_RS21175 748a53ec2c8ca5feb9ca6b04ae0001b6 943 Gene3D G3DSA:1.10.730.10 646 824 2.4E-39 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS23795 cd95046a6f49c34160fd095178b55e83 206 Gene3D G3DSA:1.10.1050.10 147 206 1.0E-15 T 29-03-2018 THSYN_RS23795 cd95046a6f49c34160fd095178b55e83 206 Gene3D G3DSA:1.10.1050.10 1 100 1.6E-40 T 29-03-2018 THSYN_RS23795 cd95046a6f49c34160fd095178b55e83 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 1.3E-76 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 THSYN_RS23795 cd95046a6f49c34160fd095178b55e83 206 Pfam PF01479 S4 domain 96 143 2.4E-18 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS23795 cd95046a6f49c34160fd095178b55e83 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 94 118 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23795 cd95046a6f49c34160fd095178b55e83 206 SUPERFAMILY SSF55174 3 206 2.22E-69 T 29-03-2018 THSYN_RS23795 cd95046a6f49c34160fd095178b55e83 206 SMART SM00363 96 160 3.3E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS23795 cd95046a6f49c34160fd095178b55e83 206 Gene3D G3DSA:3.10.290.10 101 146 2.5E-15 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS23795 cd95046a6f49c34160fd095178b55e83 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 95 2.3E-30 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 THSYN_RS23795 cd95046a6f49c34160fd095178b55e83 206 SMART SM01390 3 95 4.7E-45 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 THSYN_RS23795 cd95046a6f49c34160fd095178b55e83 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 34.305 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 Gene3D G3DSA:1.10.10.350 364 472 5.7E-25 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 2.3E-25 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 PRINTS PR00987 Glutamyl-tRNA synthetase signature 193 201 2.3E-25 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 PRINTS PR00987 Glutamyl-tRNA synthetase signature 177 187 2.3E-25 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 2.3E-25 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 2.3E-25 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 461 31.659 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 SUPERFAMILY SSF48163 297 461 1.44E-38 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 303 2.6E-105 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 SUPERFAMILY SSF52374 3 294 4.02E-110 T 29-03-2018 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 Gene3D G3DSA:3.40.50.620 3 119 3.0E-38 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 463 5.2E-170 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 Gene3D G3DSA:3.40.50.620 120 229 2.2E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 Gene3D G3DSA:1.10.1160.10 230 311 7.4E-33 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 THSYN_RS04695 de7e42a81ceb7124928d3ac9539f0608 473 Gene3D G3DSA:1.10.8.70 316 357 1.2E-5 T 29-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 THSYN_RS14610 f84871592ee8fd712dec6ecf27a83f94 624 Gene3D G3DSA:1.20.1560.10 13 328 2.4E-41 T 29-03-2018 THSYN_RS14610 f84871592ee8fd712dec6ecf27a83f94 624 SUPERFAMILY SSF90123 22 332 9.68E-51 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS14610 f84871592ee8fd712dec6ecf27a83f94 624 SMART SM00382 411 597 1.7E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS14610 f84871592ee8fd712dec6ecf27a83f94 624 Gene3D G3DSA:3.40.50.300 383 606 5.1E-44 T 29-03-2018 THSYN_RS14610 f84871592ee8fd712dec6ecf27a83f94 624 Pfam PF00664 ABC transporter transmembrane region 36 303 3.7E-27 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS14610 f84871592ee8fd712dec6ecf27a83f94 624 Pfam PF00005 ABC transporter 402 551 1.9E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS14610 f84871592ee8fd712dec6ecf27a83f94 624 SUPERFAMILY SSF52540 384 593 7.04E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14610 f84871592ee8fd712dec6ecf27a83f94 624 ProSitePatterns PS00211 ABC transporters family signature. 523 537 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS10145 82ee5b07e9088648a7dccc0c9c59f935 511 Pfam PF00534 Glycosyl transferases group 1 301 457 1.1E-16 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS10145 82ee5b07e9088648a7dccc0c9c59f935 511 Pfam PF08323 Starch synthase catalytic domain 15 252 1.2E-74 T 29-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THSYN_RS10145 82ee5b07e9088648a7dccc0c9c59f935 511 Gene3D G3DSA:3.40.50.2000 11 271 7.5E-10 T 29-03-2018 THSYN_RS10145 82ee5b07e9088648a7dccc0c9c59f935 511 Hamap MF_00484 Glycogen synthase [glgA]. 14 494 42.731 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THSYN_RS10145 82ee5b07e9088648a7dccc0c9c59f935 511 Gene3D G3DSA:3.40.50.2000 272 490 5.7E-40 T 29-03-2018 THSYN_RS10145 82ee5b07e9088648a7dccc0c9c59f935 511 SUPERFAMILY SSF53756 4 496 4.89E-118 T 29-03-2018 THSYN_RS10145 82ee5b07e9088648a7dccc0c9c59f935 511 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 15 493 7.8E-161 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THSYN_RS19165 ee6a6eaebecaff79e0b517b25d7cdb11 201 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 16 155 4.3E-13 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THSYN_RS19165 ee6a6eaebecaff79e0b517b25d7cdb11 201 SUPERFAMILY SSF52540 9 178 2.66E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19165 ee6a6eaebecaff79e0b517b25d7cdb11 201 Gene3D G3DSA:3.40.50.300 59 195 2.7E-12 T 29-03-2018 THSYN_RS19165 ee6a6eaebecaff79e0b517b25d7cdb11 201 Gene3D G3DSA:3.40.50.300 4 58 5.0E-16 T 29-03-2018 THSYN_RS19590 2845b8a8f4dbffab62e9d16a34da2870 379 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 93 103 1.6E-10 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THSYN_RS19590 2845b8a8f4dbffab62e9d16a34da2870 379 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 257 275 1.6E-10 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THSYN_RS19590 2845b8a8f4dbffab62e9d16a34da2870 379 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 28 44 1.6E-10 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THSYN_RS19590 2845b8a8f4dbffab62e9d16a34da2870 379 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 332 347 1.6E-10 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THSYN_RS19590 2845b8a8f4dbffab62e9d16a34da2870 379 Pfam PF13458 Periplasmic binding protein 27 365 4.3E-64 T 29-03-2018 IPR028081 Leucine-binding protein domain THSYN_RS19590 2845b8a8f4dbffab62e9d16a34da2870 379 Gene3D G3DSA:3.40.50.2300 158 326 6.8E-41 T 29-03-2018 THSYN_RS19590 2845b8a8f4dbffab62e9d16a34da2870 379 SUPERFAMILY SSF53822 27 370 1.85E-95 T 29-03-2018 IPR028082 Periplasmic binding protein-like I THSYN_RS19590 2845b8a8f4dbffab62e9d16a34da2870 379 Gene3D G3DSA:3.40.50.2300 26 157 1.7E-21 T 29-03-2018 THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 Pfam PF00158 Sigma-54 interaction domain 146 312 5.3E-68 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 Pfam PF02954 Bacterial regulatory protein, Fis family 422 460 9.1E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 231 246 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 SUPERFAMILY SSF52540 145 388 1.63E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 Gene3D G3DSA:3.40.50.300 142 317 3.6E-28 T 29-03-2018 THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 Gene3D G3DSA:1.10.8.60 318 385 4.6E-23 T 29-03-2018 THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 SMART SM00448 6 117 1.3E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 SUPERFAMILY SSF52172 4 189 4.98E-40 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 Gene3D G3DSA:3.40.50.2300 1 141 1.7E-31 T 29-03-2018 THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 Pfam PF00072 Response regulator receiver domain 8 114 5.8E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 SUPERFAMILY SSF46689 410 461 1.46E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 SMART SM00382 165 308 7.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS16985 2210bcae39dafec492e7e50c40dcaf35 465 Gene3D G3DSA:1.10.10.60 386 461 7.6E-12 T 29-03-2018 THSYN_RS03630 5321e245e4ba331baa9c3ccd1d7741cc 127 SMART SM00320 47 86 2.7E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS03630 5321e245e4ba331baa9c3ccd1d7741cc 127 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 73 87 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS03630 5321e245e4ba331baa9c3ccd1d7741cc 127 Gene3D G3DSA:2.130.10.10 1 123 1.2E-12 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS03630 5321e245e4ba331baa9c3ccd1d7741cc 127 SUPERFAMILY SSF82171 5 112 1.02E-10 T 29-03-2018 THSYN_RS05145 3ca8e72cc3e4ee96ac4b4eba7602578e 342 SUPERFAMILY SSF53659 20 340 1.6E-112 T 29-03-2018 THSYN_RS05145 3ca8e72cc3e4ee96ac4b4eba7602578e 342 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 48 335 7.0E-105 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 THSYN_RS05145 3ca8e72cc3e4ee96ac4b4eba7602578e 342 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 18 339 35.626 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 THSYN_RS05145 3ca8e72cc3e4ee96ac4b4eba7602578e 342 Gene3D G3DSA:3.40.718.10 14 341 7.0E-127 T 29-03-2018 THSYN_RS05145 3ca8e72cc3e4ee96ac4b4eba7602578e 342 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 21 339 1.1E-125 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 THSYN_RS32990 c0e88a8b739bd0f90cdb2b69ce5ae8da 263 SMART SM00382 47 230 2.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS32990 c0e88a8b739bd0f90cdb2b69ce5ae8da 263 Pfam PF00005 ABC transporter 39 181 5.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS32990 c0e88a8b739bd0f90cdb2b69ce5ae8da 263 TIGRFAM TIGR03864 PQQ_ABC_ATP: ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system 22 257 1.8E-98 T 29-03-2018 IPR022467 ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system THSYN_RS32990 c0e88a8b739bd0f90cdb2b69ce5ae8da 263 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS32990 c0e88a8b739bd0f90cdb2b69ce5ae8da 263 SUPERFAMILY SSF52540 21 245 3.13E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS32990 c0e88a8b739bd0f90cdb2b69ce5ae8da 263 Gene3D G3DSA:3.40.50.300 20 263 7.6E-63 T 29-03-2018 THSYN_RS01695 1ac9fc3e77282ad5b24b0404eb4785b0 521 SMART SM00798 134 453 1.5E-197 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THSYN_RS01695 1ac9fc3e77282ad5b24b0404eb4785b0 521 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 5 521 1.7E-234 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THSYN_RS01695 1ac9fc3e77282ad5b24b0404eb4785b0 521 SUPERFAMILY SSF53927 213 521 4.01E-125 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 THSYN_RS01695 1ac9fc3e77282ad5b24b0404eb4785b0 521 PIRSF PIRSF000414 1 521 1.4E-217 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THSYN_RS01695 1ac9fc3e77282ad5b24b0404eb4785b0 521 Pfam PF02142 MGS-like domain 16 129 9.6E-30 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain THSYN_RS01695 1ac9fc3e77282ad5b24b0404eb4785b0 521 Gene3D G3DSA:3.40.140.20 222 367 2.9E-50 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THSYN_RS01695 1ac9fc3e77282ad5b24b0404eb4785b0 521 SMART SM00851 16 129 4.6E-61 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain THSYN_RS01695 1ac9fc3e77282ad5b24b0404eb4785b0 521 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 4 521 45.107 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THSYN_RS01695 1ac9fc3e77282ad5b24b0404eb4785b0 521 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 452 1.0E-114 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THSYN_RS01695 1ac9fc3e77282ad5b24b0404eb4785b0 521 Gene3D G3DSA:3.40.50.1380 1 192 2.4E-74 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain THSYN_RS01695 1ac9fc3e77282ad5b24b0404eb4785b0 521 Gene3D G3DSA:3.40.140.20 369 511 1.6E-50 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THSYN_RS01695 1ac9fc3e77282ad5b24b0404eb4785b0 521 SUPERFAMILY SSF52335 4 193 4.19E-70 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain THSYN_RS23740 d171688d438e5a1524b84b6fdcfc9013 401 Hamap MF_02062 Sodium/glutamate symporter [gltS]. 3 397 23.327 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 THSYN_RS23740 d171688d438e5a1524b84b6fdcfc9013 401 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 6 397 8.4E-147 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 THSYN_RS23740 d171688d438e5a1524b84b6fdcfc9013 401 Pfam PF03616 Sodium/glutamate symporter 6 366 2.3E-131 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 THSYN_RS17650 97f36101f6a29b536607d626b09eceb3 358 SUPERFAMILY SSF46626 181 342 1.13E-34 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS17650 97f36101f6a29b536607d626b09eceb3 358 Pfam PF03150 Di-haem cytochrome c peroxidase 44 194 7.4E-52 T 29-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 THSYN_RS17650 97f36101f6a29b536607d626b09eceb3 358 PIRSF PIRSF000294 5 347 6.1E-107 T 29-03-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 THSYN_RS17650 97f36101f6a29b536607d626b09eceb3 358 SUPERFAMILY SSF46626 26 182 3.2E-50 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS17650 97f36101f6a29b536607d626b09eceb3 358 Gene3D G3DSA:1.10.760.10 32 197 2.0E-49 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS17650 97f36101f6a29b536607d626b09eceb3 358 Gene3D G3DSA:1.10.760.10 198 339 4.3E-20 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS17650 97f36101f6a29b536607d626b09eceb3 358 Pfam PF00034 Cytochrome c 202 324 1.8E-6 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS21800 0694d76131ba9122c05c7e459d0b939f 556 Gene3D G3DSA:3.40.50.150 18 248 5.1E-29 T 29-03-2018 THSYN_RS21800 0694d76131ba9122c05c7e459d0b939f 556 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 119 125 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS21800 0694d76131ba9122c05c7e459d0b939f 556 Pfam PF02384 N-6 DNA Methylase 17 197 1.0E-14 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS21800 0694d76131ba9122c05c7e459d0b939f 556 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 44 58 2.4E-18 T 29-03-2018 THSYN_RS21800 0694d76131ba9122c05c7e459d0b939f 556 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 116 128 2.4E-18 T 29-03-2018 THSYN_RS21800 0694d76131ba9122c05c7e459d0b939f 556 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 20 36 2.4E-18 T 29-03-2018 THSYN_RS21800 0694d76131ba9122c05c7e459d0b939f 556 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 155 179 2.4E-18 T 29-03-2018 THSYN_RS21800 0694d76131ba9122c05c7e459d0b939f 556 SUPERFAMILY SSF53335 14 237 7.68E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS21985 ce4192348d9fb68158c97a321f65650b 175 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 30 169 2.0E-60 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THSYN_RS21985 ce4192348d9fb68158c97a321f65650b 175 SUPERFAMILY SSF54637 28 169 1.45E-48 T 29-03-2018 IPR029069 HotDog domain THSYN_RS21985 ce4192348d9fb68158c97a321f65650b 175 Gene3D G3DSA:3.10.129.10 9 174 1.0E-55 T 29-03-2018 THSYN_RS21985 ce4192348d9fb68158c97a321f65650b 175 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 30 172 35.572 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THSYN_RS21985 ce4192348d9fb68158c97a321f65650b 175 Pfam PF07977 FabA-like domain 39 164 9.7E-38 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THSYN_RS17700 7acf1f537d3bcd894603fc440ce2ab2c 1084 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 113 180 2.4E-4 T 29-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 THSYN_RS17700 7acf1f537d3bcd894603fc440ce2ab2c 1084 SUPERFAMILY SSF53335 113 169 2.96E-15 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS17700 7acf1f537d3bcd894603fc440ce2ab2c 1084 SUPERFAMILY SSF53335 625 656 2.96E-15 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS17700 7acf1f537d3bcd894603fc440ce2ab2c 1084 SUPERFAMILY SSF53335 725 775 2.96E-15 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS17700 7acf1f537d3bcd894603fc440ce2ab2c 1084 Gene3D G3DSA:3.40.50.150 36 805 4.7E-44 T 29-03-2018 THSYN_RS17700 7acf1f537d3bcd894603fc440ce2ab2c 1084 Pfam PF06634 Protein of unknown function (DUF1156) 10 60 1.3E-17 T 29-03-2018 IPR009537 Domain of unknown function DUF1156 THSYN_RS17700 7acf1f537d3bcd894603fc440ce2ab2c 1084 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 650 656 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS22905 e398dece9b4329cf9a04ab1e1867da68 218 TIGRFAM TIGR01298 RNaseT: ribonuclease T 12 205 2.1E-93 T 29-03-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 THSYN_RS22905 e398dece9b4329cf9a04ab1e1867da68 218 Pfam PF00929 Exonuclease 21 195 8.6E-30 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THSYN_RS22905 e398dece9b4329cf9a04ab1e1867da68 218 SUPERFAMILY SSF53098 13 205 5.06E-53 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS22905 e398dece9b4329cf9a04ab1e1867da68 218 SMART SM00479 19 204 6.8E-29 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THSYN_RS22905 e398dece9b4329cf9a04ab1e1867da68 218 Gene3D G3DSA:3.30.420.10 20 206 2.4E-31 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS22905 e398dece9b4329cf9a04ab1e1867da68 218 Hamap MF_00157 Ribonuclease T [rnt]. 1 218 89.209 T 29-03-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 THSYN_RS21055 bd091760e107f6562ca7214dda51d103 328 Gene3D G3DSA:3.40.50.1820 27 327 1.9E-12 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS21055 bd091760e107f6562ca7214dda51d103 328 SUPERFAMILY SSF53474 58 311 9.08E-13 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS29635 856ef36382030aada62833a32518a4b5 269 Pfam PF04909 Amidohydrolase 75 216 9.3E-10 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 THSYN_RS29635 856ef36382030aada62833a32518a4b5 269 SUPERFAMILY SSF51556 13 260 2.82E-19 T 29-03-2018 IPR032466 Metal-dependent hydrolase THSYN_RS29635 856ef36382030aada62833a32518a4b5 269 Gene3D G3DSA:3.20.20.140 11 268 2.0E-21 T 29-03-2018 THSYN_RS14885 e04bb7f2cd23561ad6186320865b331a 495 Pfam PF12146 Serine aminopeptidase, S33 117 346 2.6E-14 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 THSYN_RS14885 e04bb7f2cd23561ad6186320865b331a 495 SUPERFAMILY SSF53474 113 345 1.03E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS14885 e04bb7f2cd23561ad6186320865b331a 495 Gene3D G3DSA:3.40.50.1820 39 400 7.2E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS05560 f3c298834cd0e7ac259d6b4f18b3ea73 551 Pfam PF13191 AAA ATPase domain 294 482 8.0E-36 T 29-03-2018 THSYN_RS05560 f3c298834cd0e7ac259d6b4f18b3ea73 551 Gene3D G3DSA:1.10.510.10 92 275 3.5E-27 T 29-03-2018 THSYN_RS05560 f3c298834cd0e7ac259d6b4f18b3ea73 551 SMART SM00220 10 263 6.9E-6 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS05560 f3c298834cd0e7ac259d6b4f18b3ea73 551 Pfam PF00069 Protein kinase domain 104 261 7.5E-10 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS05560 f3c298834cd0e7ac259d6b4f18b3ea73 551 SUPERFAMILY SSF56112 44 260 9.65E-27 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS05560 f3c298834cd0e7ac259d6b4f18b3ea73 551 SUPERFAMILY SSF52540 390 504 3.04E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05560 f3c298834cd0e7ac259d6b4f18b3ea73 551 SUPERFAMILY SSF52540 280 348 3.04E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05560 f3c298834cd0e7ac259d6b4f18b3ea73 551 Gene3D G3DSA:3.40.50.300 278 494 9.5E-11 T 29-03-2018 THSYN_RS32010 fe3950f7a9ca1ae45f4f565fd37cd255 353 Gene3D G3DSA:3.30.420.190 124 350 3.7E-79 T 29-03-2018 THSYN_RS32010 fe3950f7a9ca1ae45f4f565fd37cd255 353 Gene3D G3DSA:3.30.420.40 8 122 2.6E-33 T 29-03-2018 THSYN_RS32010 fe3950f7a9ca1ae45f4f565fd37cd255 353 Pfam PF01968 Hydantoinase/oxoprolinase 65 312 5.3E-11 T 29-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 THSYN_RS32010 fe3950f7a9ca1ae45f4f565fd37cd255 353 TIGRFAM TIGR03123 one_C_unchar_1: probable H4MPT-linked C1 transfer pathway protein 9 348 1.6E-103 T 29-03-2018 IPR002756 4-[[4-(2-aminoethyl)phenoxy]-methyl]-2-furanmethanamine-glutamate synthase THSYN_RS32010 fe3950f7a9ca1ae45f4f565fd37cd255 353 SUPERFAMILY SSF53067 124 275 5.18E-7 T 29-03-2018 THSYN_RS32010 fe3950f7a9ca1ae45f4f565fd37cd255 353 SUPERFAMILY SSF53067 8 80 5.18E-7 T 29-03-2018 THSYN_RS16815 9029e26e0fbcffd2b1e04acba5d8df03 359 SUPERFAMILY SSF55874 231 354 7.78E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS16815 9029e26e0fbcffd2b1e04acba5d8df03 359 Gene3D G3DSA:3.30.565.10 174 354 1.3E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS16815 9029e26e0fbcffd2b1e04acba5d8df03 359 Pfam PF06580 Histidine kinase 164 242 9.5E-22 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 Pfam PF00072 Response regulator receiver domain 18 127 1.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 Pfam PF00563 EAL domain 488 722 1.6E-71 T 29-03-2018 IPR001633 EAL domain THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 PIRSF PIRSF005925 298 740 1.2E-149 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 PIRSF PIRSF005925 176 304 2.6E-13 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 SMART SM00091 186 252 2.1E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 Pfam PF13426 PAS domain 197 299 2.2E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 SMART SM00052 482 727 1.5E-122 T 29-03-2018 IPR001633 EAL domain THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 Gene3D G3DSA:3.40.50.10600 183 306 6.6E-29 T 29-03-2018 THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 Gene3D G3DSA:3.20.20.450 476 739 1.6E-100 T 29-03-2018 IPR001633 EAL domain THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 SMART SM00448 16 127 5.1E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 Gene3D G3DSA:3.30.450.20 139 182 0.47 T 29-03-2018 THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 SMART SM00267 300 472 1.9E-69 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 SUPERFAMILY SSF55073 316 472 9.42E-51 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 SUPERFAMILY SSF141868 487 733 4.58E-90 T 29-03-2018 IPR001633 EAL domain THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 SUPERFAMILY SSF55785 191 298 8.03E-32 T 29-03-2018 IPR000014 PAS domain THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 190 306 3.9E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 SUPERFAMILY SSF52172 15 144 1.57E-37 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 Gene3D G3DSA:3.30.70.270 307 475 6.9E-62 T 29-03-2018 THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 308 469 1.3E-47 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 SMART SM00086 258 300 5.4E-7 T 29-03-2018 IPR001610 PAC motif THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 Pfam PF00990 Diguanylate cyclase, GGDEF domain 311 468 1.4E-50 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS02000 27b1a191fb1eb4853d97bdaeaeae7058 740 Gene3D G3DSA:3.40.50.2300 2 138 1.4E-36 T 29-03-2018 THSYN_RS20805 3a1e7bde71fde2dd6bd70d86477f14ce 354 SUPERFAMILY SSF103088 243 352 3.79E-31 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS20805 3a1e7bde71fde2dd6bd70d86477f14ce 354 Gene3D G3DSA:3.30.1330.60 106 353 1.3E-34 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS20805 3a1e7bde71fde2dd6bd70d86477f14ce 354 Pfam PF00691 OmpA family 251 347 1.2E-17 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS20805 3a1e7bde71fde2dd6bd70d86477f14ce 354 PRINTS PR01021 OMPA domain signature 297 313 5.2E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS20805 3a1e7bde71fde2dd6bd70d86477f14ce 354 PRINTS PR01021 OMPA domain signature 252 274 5.2E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS20805 3a1e7bde71fde2dd6bd70d86477f14ce 354 PRINTS PR01021 OMPA domain signature 282 297 5.2E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS10040 a9b808e9f085089b6f8c728194c295a7 341 Gene3D G3DSA:3.40.50.300 79 325 1.6E-29 T 29-03-2018 THSYN_RS10040 a9b808e9f085089b6f8c728194c295a7 341 Pfam PF00005 ABC transporter 118 274 7.1E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS10040 a9b808e9f085089b6f8c728194c295a7 341 SMART SM00382 118 325 1.4E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS10040 a9b808e9f085089b6f8c728194c295a7 341 SUPERFAMILY SSF52540 118 325 6.27E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21120 95c4825554bcdec73392e80b69cdc27a 356 Gene3D G3DSA:3.40.190.10 25 148 1.1E-16 T 29-03-2018 THSYN_RS21120 95c4825554bcdec73392e80b69cdc27a 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 172 191 2.3E-29 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS21120 95c4825554bcdec73392e80b69cdc27a 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 300 326 2.3E-29 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS21120 95c4825554bcdec73392e80b69cdc27a 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 2.3E-29 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS21120 95c4825554bcdec73392e80b69cdc27a 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 81 95 2.3E-29 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS21120 95c4825554bcdec73392e80b69cdc27a 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 127 143 2.3E-29 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS21120 95c4825554bcdec73392e80b69cdc27a 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 37 53 2.3E-29 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS21120 95c4825554bcdec73392e80b69cdc27a 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 53 74 2.3E-29 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS21120 95c4825554bcdec73392e80b69cdc27a 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 97 110 2.3E-29 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS21120 95c4825554bcdec73392e80b69cdc27a 356 Pfam PF13416 Bacterial extracellular solute-binding protein 47 321 1.2E-27 T 29-03-2018 THSYN_RS21120 95c4825554bcdec73392e80b69cdc27a 356 SUPERFAMILY SSF53850 32 353 2.13E-66 T 29-03-2018 THSYN_RS21120 95c4825554bcdec73392e80b69cdc27a 356 Gene3D G3DSA:3.40.190.10 149 307 6.3E-29 T 29-03-2018 THSYN_RS24370 e7784c1d06bd95de7a7ae2e34b316bb6 608 Gene3D G3DSA:1.20.1560.10 8 342 2.5E-55 T 29-03-2018 THSYN_RS24370 e7784c1d06bd95de7a7ae2e34b316bb6 608 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS24370 e7784c1d06bd95de7a7ae2e34b316bb6 608 Gene3D G3DSA:3.40.50.300 344 596 2.7E-76 T 29-03-2018 THSYN_RS24370 e7784c1d06bd95de7a7ae2e34b316bb6 608 Pfam PF00005 ABC transporter 371 520 1.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS24370 e7784c1d06bd95de7a7ae2e34b316bb6 608 SUPERFAMILY SSF90123 24 341 6.15E-58 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS24370 e7784c1d06bd95de7a7ae2e34b316bb6 608 SUPERFAMILY SSF52540 345 590 1.09E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24370 e7784c1d06bd95de7a7ae2e34b316bb6 608 Pfam PF00664 ABC transporter transmembrane region 37 308 1.2E-31 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS24370 e7784c1d06bd95de7a7ae2e34b316bb6 608 SMART SM00382 380 566 3.0E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS18315 6e573eceab14c14aeea8fcebf3c47096 286 Pfam PF13672 Protein phosphatase 2C 44 263 1.2E-48 T 29-03-2018 THSYN_RS18315 6e573eceab14c14aeea8fcebf3c47096 286 Gene3D G3DSA:3.60.40.10 36 208 3.0E-13 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS18315 6e573eceab14c14aeea8fcebf3c47096 286 SUPERFAMILY SSF81606 42 223 2.62E-14 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 Gene3D G3DSA:2.60.40.10 620 722 3.3E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 179 190 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 SUPERFAMILY SSF52743 249 470 1.83E-53 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 SUPERFAMILY SSF52743 152 210 1.83E-53 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 SUPERFAMILY SSF49313 638 722 1.37E-7 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 SUPERFAMILY SSF49785 730 867 3.4E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 256 266 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 Gene3D G3DSA:2.60.120.430 725 873 1.2E-13 T 29-03-2018 THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 Gene3D G3DSA:2.60.120.430 984 1138 1.7E-13 T 29-03-2018 THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 PRINTS PR00723 Subtilisin serine protease family (S8) signature 252 265 1.3E-15 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 PRINTS PR00723 Subtilisin serine protease family (S8) signature 174 193 1.3E-15 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 PRINTS PR00723 Subtilisin serine protease family (S8) signature 422 438 1.3E-15 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 423 433 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 Pfam PF05345 Putative Ig domain 663 699 5.9E-6 T 29-03-2018 IPR008009 Putative Ig THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 Gene3D G3DSA:2.60.40.10 884 981 1.0E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 SUPERFAMILY SSF49785 989 1138 2.04E-20 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 Gene3D G3DSA:3.40.50.200 147 503 2.6E-57 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS07245 720e43e204cad6e80f4f439f65975fc8 1140 Pfam PF00082 Subtilase family 174 449 4.4E-32 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS28480 cc28d11fdf98466d1f1871a87e4b6a70 489 SUPERFAMILY SSF88713 50 466 1.41E-50 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS28480 cc28d11fdf98466d1f1871a87e4b6a70 489 Gene3D G3DSA:3.20.110.10 113 276 5.9E-11 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain THSYN_RS28480 cc28d11fdf98466d1f1871a87e4b6a70 489 Gene3D G3DSA:3.20.110.10 277 412 0.19 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain THSYN_RS28480 cc28d11fdf98466d1f1871a87e4b6a70 489 Pfam PF03065 Glycosyl hydrolase family 57 152 249 3.9E-5 T 29-03-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 Gene3D G3DSA:1.20.58.280 555 579 0.015 T 29-03-2018 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 Gene3D G3DSA:1.20.58.280 693 719 0.0087 T 29-03-2018 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 Gene3D G3DSA:1.10.150.200 490 554 1.1E-10 T 29-03-2018 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 Gene3D G3DSA:1.20.1250.10 740 816 2.0E-9 T 29-03-2018 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 Gene3D G3DSA:1.20.1250.10 600 671 8.8E-12 T 29-03-2018 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 Pfam PF13374 Tetratricopeptide repeat 736 771 0.0051 T 29-03-2018 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 Pfam PF13374 Tetratricopeptide repeat 644 687 0.0017 T 29-03-2018 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 Gene3D G3DSA:3.30.70.100 580 599 0.016 T 29-03-2018 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 Gene3D G3DSA:1.20.120.420 392 489 7.6E-7 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 SUPERFAMILY SSF48452 405 565 1.6E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 SUPERFAMILY SSF48452 712 796 2.02E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 SUPERFAMILY SSF48452 527 699 4.17E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 Gene3D G3DSA:1.20.5.1140 720 739 9.6E-5 T 29-03-2018 THSYN_RS13455 0637283329ccfc57386491ea517254b7 862 Gene3D G3DSA:1.20.5.1140 672 692 3.2E-4 T 29-03-2018 THSYN_RS29045 edfc57779258bc8204837e31ff0b2558 238 Gene3D G3DSA:3.40.50.150 4 183 2.2E-8 T 29-03-2018 THSYN_RS29045 edfc57779258bc8204837e31ff0b2558 238 SUPERFAMILY SSF53335 57 167 2.8E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS18085 db3253efddf9809b09267127c6b94400 139 Gene3D G3DSA:3.40.50.1010 1 121 1.8E-14 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS18085 db3253efddf9809b09267127c6b94400 139 SUPERFAMILY SSF88723 5 114 1.96E-13 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS18085 db3253efddf9809b09267127c6b94400 139 Pfam PF01850 PIN domain 5 113 1.9E-8 T 29-03-2018 IPR002716 PIN domain THSYN_RS19505 88889e5c9aa04a2fec3ea03d061d2c18 137 SUPERFAMILY SSF47413 1 66 5.9E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS19505 88889e5c9aa04a2fec3ea03d061d2c18 137 SMART SM00530 6 61 8.1E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS19505 88889e5c9aa04a2fec3ea03d061d2c18 137 Pfam PF01381 Helix-turn-helix 7 61 2.9E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS19505 88889e5c9aa04a2fec3ea03d061d2c18 137 Gene3D G3DSA:1.10.260.40 1 137 1.6E-19 T 29-03-2018 THSYN_RS26190 6ed8e48a0bbb79382b45f7508a875abc 280 Gene3D G3DSA:3.90.226.10 116 278 5.4E-13 T 29-03-2018 THSYN_RS26190 6ed8e48a0bbb79382b45f7508a875abc 280 SUPERFAMILY SSF52096 122 220 8.15E-13 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS15775 5ffe5d3d8e85ff34b19b394b6b7193c4 295 TIGRFAM TIGR01932 hflC: HflC protein 145 286 4.9E-44 T 29-03-2018 IPR010200 HflC GO:0016021|GO:0052547 THSYN_RS15775 5ffe5d3d8e85ff34b19b394b6b7193c4 295 PIRSF PIRSF005651 2 295 8.2E-90 T 29-03-2018 IPR010200 HflC GO:0016021|GO:0052547 THSYN_RS15775 5ffe5d3d8e85ff34b19b394b6b7193c4 295 PRINTS PR00721 Stomatin signature 31 53 4.7E-7 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS15775 5ffe5d3d8e85ff34b19b394b6b7193c4 295 PRINTS PR00721 Stomatin signature 182 203 4.7E-7 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS15775 5ffe5d3d8e85ff34b19b394b6b7193c4 295 PRINTS PR00721 Stomatin signature 163 181 4.7E-7 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS15775 5ffe5d3d8e85ff34b19b394b6b7193c4 295 PRINTS PR00721 Stomatin signature 79 100 4.7E-7 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS15775 5ffe5d3d8e85ff34b19b394b6b7193c4 295 SUPERFAMILY SSF117892 56 193 6.54E-29 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS15775 5ffe5d3d8e85ff34b19b394b6b7193c4 295 Pfam PF01145 SPFH domain / Band 7 family 28 203 1.1E-30 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS15775 5ffe5d3d8e85ff34b19b394b6b7193c4 295 SMART SM00244 24 187 8.8E-31 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS31450 7f8221855b16dfbd3040ee3514a5fa5d 177 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 159 6.7E-22 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component THSYN_RS06875 c52f6fa3e5e849b0efa8b0049739d894 191 Pfam PF08269 Cache domain 69 171 1.2E-18 T 29-03-2018 IPR004010 Double Cache domain 2 THSYN_RS06875 c52f6fa3e5e849b0efa8b0049739d894 191 SMART SM01049 39 116 6.2E-5 T 29-03-2018 IPR033480 Single Cache domain 2 THSYN_RS06875 c52f6fa3e5e849b0efa8b0049739d894 191 Gene3D G3DSA:3.30.450.20 24 185 5.8E-27 T 29-03-2018 THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 SUPERFAMILY SSF47226 15 109 8.64E-15 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 Gene3D G3DSA:3.40.50.2300 155 280 2.4E-18 T 29-03-2018 THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 Gene3D G3DSA:3.40.50.2300 281 409 8.8E-32 T 29-03-2018 THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 Pfam PF00072 Response regulator receiver domain 162 273 2.0E-9 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 Pfam PF00072 Response regulator receiver domain 288 399 8.1E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 SMART SM00267 402 573 9.2E-52 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 SMART SM00448 286 399 1.8E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 SMART SM00448 160 274 9.3E-7 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 Gene3D G3DSA:3.30.70.270 410 574 2.7E-51 T 29-03-2018 THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 411 573 7.7E-44 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 Pfam PF00990 Diguanylate cyclase, GGDEF domain 415 569 1.9E-38 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 SUPERFAMILY SSF55073 418 572 4.94E-46 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 Gene3D G3DSA:1.20.120.160 11 111 2.3E-14 T 29-03-2018 THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 SUPERFAMILY SSF52172 161 280 2.85E-18 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 Pfam PF01627 Hpt domain 16 108 9.3E-12 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS04355 1817aa11e9e2e3a58f9e3e389cd0be6a 589 SUPERFAMILY SSF52172 285 414 2.42E-34 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS20255 7dc0e4cca9724d8226307743c826121d 86 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 13 74 9.6E-21 T 29-03-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system THSYN_RS20255 7dc0e4cca9724d8226307743c826121d 86 Gene3D G3DSA:1.10.1220.10 63 86 0.057 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS20255 7dc0e4cca9724d8226307743c826121d 86 Gene3D G3DSA:1.10.1220.10 32 57 0.029 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS15645 ba424bf62ae9132434bee98e6eab70be 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 203 299 4.1E-14 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 THSYN_RS15645 ba424bf62ae9132434bee98e6eab70be 562 Gene3D G3DSA:3.40.50.1220 196 349 1.0E-17 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS15645 ba424bf62ae9132434bee98e6eab70be 562 Gene3D G3DSA:3.40.50.970 1 195 8.4E-40 T 29-03-2018 THSYN_RS15645 ba424bf62ae9132434bee98e6eab70be 562 PIRSF PIRSF036565 1 555 1.2E-147 T 29-03-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 THSYN_RS15645 ba424bf62ae9132434bee98e6eab70be 562 SUPERFAMILY SSF52518 362 542 1.18E-38 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS15645 ba424bf62ae9132434bee98e6eab70be 562 SUPERFAMILY SSF52518 4 177 1.98E-37 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS15645 ba424bf62ae9132434bee98e6eab70be 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 174 1.3E-31 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THSYN_RS15645 ba424bf62ae9132434bee98e6eab70be 562 Gene3D G3DSA:3.40.50.970 358 540 3.9E-30 T 29-03-2018 THSYN_RS15645 ba424bf62ae9132434bee98e6eab70be 562 SUPERFAMILY SSF52467 165 346 6.87E-24 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS15645 ba424bf62ae9132434bee98e6eab70be 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 403 531 9.4E-20 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THSYN_RS08095 da1187eefe82098eeee0df93eafeb493 1033 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 128 217 2.8E-11 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THSYN_RS08095 da1187eefe82098eeee0df93eafeb493 1033 Gene3D G3DSA:3.40.50.300 273 499 7.5E-23 T 29-03-2018 THSYN_RS08095 da1187eefe82098eeee0df93eafeb493 1033 SMART SM00487 285 510 1.5E-8 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS08095 da1187eefe82098eeee0df93eafeb493 1033 Pfam PF04851 Type III restriction enzyme, res subunit 289 443 2.0E-13 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS08095 da1187eefe82098eeee0df93eafeb493 1033 SUPERFAMILY SSF52540 256 431 1.0E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08095 da1187eefe82098eeee0df93eafeb493 1033 SUPERFAMILY SSF52540 476 529 1.0E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12405 3366a4fa56482eaa823c74906acfea8e 394 SUPERFAMILY SSF53756 7 378 2.01E-75 T 29-03-2018 THSYN_RS12405 3366a4fa56482eaa823c74906acfea8e 394 Gene3D G3DSA:3.40.50.2000 193 359 2.6E-40 T 29-03-2018 THSYN_RS12405 3366a4fa56482eaa823c74906acfea8e 394 Pfam PF13692 Glycosyl transferases group 1 207 342 1.5E-25 T 29-03-2018 THSYN_RS12405 3366a4fa56482eaa823c74906acfea8e 394 Gene3D G3DSA:3.40.50.2000 4 192 6.0E-20 T 29-03-2018 THSYN_RS12405 3366a4fa56482eaa823c74906acfea8e 394 Pfam PF13439 Glycosyltransferase Family 4 18 185 3.4E-28 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS10370 c5b8bfc390f3fb1fd4b79e25a236ca70 398 Gene3D G3DSA:3.20.20.70 3 290 5.2E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS10370 c5b8bfc390f3fb1fd4b79e25a236ca70 398 Pfam PF04055 Radical SAM superfamily 10 175 3.4E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS10370 c5b8bfc390f3fb1fd4b79e25a236ca70 398 Pfam PF06969 HemN C-terminal domain 306 368 1.1E-7 T 29-03-2018 IPR010723 HemN, C-terminal THSYN_RS10370 c5b8bfc390f3fb1fd4b79e25a236ca70 398 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 7 369 4.9E-103 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 THSYN_RS10370 c5b8bfc390f3fb1fd4b79e25a236ca70 398 SUPERFAMILY SSF102114 2 380 2.09E-101 T 29-03-2018 THSYN_RS10370 c5b8bfc390f3fb1fd4b79e25a236ca70 398 SMART SM00729 5 223 1.9E-50 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS07375 0e78937a293b32befec4523edbb5bd66 193 PIRSF PIRSF001467 10 193 3.6E-79 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 THSYN_RS07375 0e78937a293b32befec4523edbb5bd66 193 SUPERFAMILY SSF50891 18 193 6.57E-76 T 29-03-2018 IPR029000 Cyclophilin-like domain THSYN_RS07375 0e78937a293b32befec4523edbb5bd66 193 Gene3D G3DSA:2.40.100.10 14 193 3.8E-76 T 29-03-2018 IPR029000 Cyclophilin-like domain THSYN_RS07375 0e78937a293b32befec4523edbb5bd66 193 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 82 94 1.8E-40 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THSYN_RS07375 0e78937a293b32befec4523edbb5bd66 193 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 46 61 1.8E-40 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THSYN_RS07375 0e78937a293b32befec4523edbb5bd66 193 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 140 152 1.8E-40 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THSYN_RS07375 0e78937a293b32befec4523edbb5bd66 193 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 125 140 1.8E-40 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THSYN_RS07375 0e78937a293b32befec4523edbb5bd66 193 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 153 168 1.8E-40 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THSYN_RS07375 0e78937a293b32befec4523edbb5bd66 193 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 32 191 5.6E-50 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THSYN_RS07375 0e78937a293b32befec4523edbb5bd66 193 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 77 94 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 Gene3D G3DSA:3.40.50.720 143 266 5.9E-36 T 29-03-2018 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 7 123 1.3E-39 T 29-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 SUPERFAMILY SSF53223 3 124 3.07E-40 T 29-03-2018 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 262 270 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 SUPERFAMILY SSF51735 125 283 1.07E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 36 58 2.0E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 206 235 2.0E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 112 133 2.0E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 157 177 2.0E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 77 104 2.0E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 241 257 2.0E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 258 276 2.0E-81 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 Hamap MF_01576 Bifunctional protein FolD [folD]. 5 285 38.273 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 126 283 6.9E-66 T 29-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 THSYN_RS27130 e50b91e7d975e90a4a7046f1d22d8a93 291 Gene3D G3DSA:3.40.50.10860 13 142 1.2E-49 T 29-03-2018 THSYN_RS18770 ed4a9a63a06f2af5a7945716f9197bf1 451 SUPERFAMILY SSF52540 177 439 6.36E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS18770 ed4a9a63a06f2af5a7945716f9197bf1 451 SMART SM00382 185 353 5.0E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS18770 ed4a9a63a06f2af5a7945716f9197bf1 451 Gene3D G3DSA:3.40.50.300 172 396 5.3E-22 T 29-03-2018 THSYN_RS18770 ed4a9a63a06f2af5a7945716f9197bf1 451 Pfam PF07728 AAA domain (dynein-related subfamily) 189 341 3.7E-14 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 263 276 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 Gene3D G3DSA:3.40.50.10490 1 140 2.8E-45 T 29-03-2018 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 495 512 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 Gene3D G3DSA:3.40.50.10490 141 256 1.4E-52 T 29-03-2018 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 Gene3D G3DSA:1.10.1390.10 511 552 7.7E-19 T 29-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 SUPERFAMILY SSF53697 5 546 6.95E-219 T 29-03-2018 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 Gene3D G3DSA:3.40.50.10490 257 510 1.8E-121 T 29-03-2018 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 43 522 41.661 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 Pfam PF00342 Phosphoglucose isomerase 49 539 8.7E-232 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 PRINTS PR00662 Glucose-6-phosphate isomerase signature 336 357 8.1E-55 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 PRINTS PR00662 Glucose-6-phosphate isomerase signature 481 495 8.1E-55 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 PRINTS PR00662 Glucose-6-phosphate isomerase signature 495 508 8.1E-55 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 PRINTS PR00662 Glucose-6-phosphate isomerase signature 463 481 8.1E-55 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 PRINTS PR00662 Glucose-6-phosphate isomerase signature 259 277 8.1E-55 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS10135 b095d333a72842776e7cb2bfe39caa5c 552 PRINTS PR00662 Glucose-6-phosphate isomerase signature 147 166 8.1E-55 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS22020 d691ca0deeeabb273d96eebc9be4de3d 238 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 1 221 34.327 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 THSYN_RS22020 d691ca0deeeabb273d96eebc9be4de3d 238 SUPERFAMILY SSF64005 1 216 4.71E-76 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 THSYN_RS22020 d691ca0deeeabb273d96eebc9be4de3d 238 Pfam PF01255 Putative undecaprenyl diphosphate synthase 1 220 1.0E-74 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 THSYN_RS22020 d691ca0deeeabb273d96eebc9be4de3d 238 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 1 220 3.1E-79 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 THSYN_RS22020 d691ca0deeeabb273d96eebc9be4de3d 238 Gene3D G3DSA:3.40.1180.10 1 223 9.1E-77 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 THSYN_RS21215 cf38b62e20dfeef94cf3c1c2567adc3e 277 Gene3D G3DSA:3.20.190.10 2 123 9.8E-22 T 29-03-2018 THSYN_RS21215 cf38b62e20dfeef94cf3c1c2567adc3e 277 SUPERFAMILY SSF81624 2 130 8.77E-19 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 THSYN_RS21215 cf38b62e20dfeef94cf3c1c2567adc3e 277 Gene3D G3DSA:1.10.8.50 124 271 3.8E-36 T 29-03-2018 THSYN_RS21215 cf38b62e20dfeef94cf3c1c2567adc3e 277 SMART SM00898 2 107 5.6E-11 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 THSYN_RS21215 cf38b62e20dfeef94cf3c1c2567adc3e 277 SUPERFAMILY SSF57716 218 260 7.41E-10 T 29-03-2018 THSYN_RS21215 cf38b62e20dfeef94cf3c1c2567adc3e 277 Pfam PF06827 Zinc finger found in FPG and IleRS 233 260 1.5E-5 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 THSYN_RS21215 cf38b62e20dfeef94cf3c1c2567adc3e 277 ProSitePatterns PS01242 Zinc finger FPG-type signature. 234 260 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 THSYN_RS21215 cf38b62e20dfeef94cf3c1c2567adc3e 277 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 102 5.2E-11 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 THSYN_RS21215 cf38b62e20dfeef94cf3c1c2567adc3e 277 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 123 208 2.7E-12 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 THSYN_RS21215 cf38b62e20dfeef94cf3c1c2567adc3e 277 SMART SM01232 123 218 1.4E-11 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 THSYN_RS21215 cf38b62e20dfeef94cf3c1c2567adc3e 277 SUPERFAMILY SSF46946 123 204 6.48E-16 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 THSYN_RS11385 8d127c9750e696ead2b634e88e08af7f 63 SUPERFAMILY SSF81593 20 59 7.06E-7 T 29-03-2018 THSYN_RS11385 8d127c9750e696ead2b634e88e08af7f 63 Gene3D G3DSA:1.20.120.330 20 61 1.1E-4 T 29-03-2018 THSYN_RS00335 ab8ec914a234705c065d03ae1659c78f 508 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 411 501 1.1E-28 T 29-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain THSYN_RS00335 ab8ec914a234705c065d03ae1659c78f 508 SUPERFAMILY SSF52540 190 504 4.11E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00335 ab8ec914a234705c065d03ae1659c78f 508 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 209 224 1.3E-5 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 THSYN_RS00335 ab8ec914a234705c065d03ae1659c78f 508 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 290 304 1.3E-5 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 THSYN_RS00335 ab8ec914a234705c065d03ae1659c78f 508 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 342 354 1.3E-5 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 THSYN_RS00335 ab8ec914a234705c065d03ae1659c78f 508 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 318 331 1.3E-5 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 THSYN_RS00335 ab8ec914a234705c065d03ae1659c78f 508 Pfam PF01078 Magnesium chelatase, subunit ChlI 190 394 2.2E-98 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain THSYN_RS00335 ab8ec914a234705c065d03ae1659c78f 508 SMART SM00382 210 393 5.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS00335 ab8ec914a234705c065d03ae1659c78f 508 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 501 1.3E-187 T 29-03-2018 IPR004482 Mg chelatase-related protein THSYN_RS00335 ab8ec914a234705c065d03ae1659c78f 508 SUPERFAMILY SSF54211 10 169 1.74E-29 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS00335 ab8ec914a234705c065d03ae1659c78f 508 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 9.8E-42 T 29-03-2018 THSYN_RS00335 ab8ec914a234705c065d03ae1659c78f 508 Gene3D G3DSA:3.40.50.300 187 390 3.8E-23 T 29-03-2018 THSYN_RS00335 ab8ec914a234705c065d03ae1659c78f 508 Gene3D G3DSA:3.30.230.10 5 181 5.5E-38 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS28840 5a16d0e4a3cb73a55b0c04506200b43c 805 Pfam PF11412 Disulphide bond corrector protein DsbC 29 144 3.1E-32 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THSYN_RS28840 5a16d0e4a3cb73a55b0c04506200b43c 805 Pfam PF11412 Disulphide bond corrector protein DsbC 204 323 9.0E-25 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THSYN_RS28840 5a16d0e4a3cb73a55b0c04506200b43c 805 Gene3D G3DSA:2.60.40.1250 197 329 2.9E-28 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THSYN_RS28840 5a16d0e4a3cb73a55b0c04506200b43c 805 Gene3D G3DSA:2.60.40.1250 25 154 1.6E-35 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THSYN_RS28840 5a16d0e4a3cb73a55b0c04506200b43c 805 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 389 594 6.5E-16 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 THSYN_RS28840 5a16d0e4a3cb73a55b0c04506200b43c 805 Gene3D G3DSA:3.40.30.10 713 803 7.1E-10 T 29-03-2018 THSYN_RS28840 5a16d0e4a3cb73a55b0c04506200b43c 805 Gene3D G3DSA:3.40.30.10 675 712 8.9E-4 T 29-03-2018 THSYN_RS28840 5a16d0e4a3cb73a55b0c04506200b43c 805 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 10 801 34.535 T 29-03-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 THSYN_RS28840 5a16d0e4a3cb73a55b0c04506200b43c 805 SUPERFAMILY SSF74863 28 145 3.53E-32 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THSYN_RS28840 5a16d0e4a3cb73a55b0c04506200b43c 805 SUPERFAMILY SSF52833 696 798 4.31E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS28840 5a16d0e4a3cb73a55b0c04506200b43c 805 Pfam PF13899 Thioredoxin-like 691 773 3.1E-16 T 29-03-2018 THSYN_RS28840 5a16d0e4a3cb73a55b0c04506200b43c 805 SUPERFAMILY SSF74863 201 323 8.11E-26 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 SUPERFAMILY SSF52540 610 924 1.77E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 ProSitePatterns PS00211 ABC transporters family signature. 1419 1433 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 Gene3D G3DSA:1.20.1580.10 1119 1419 2.4E-54 T 29-03-2018 THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 Gene3D G3DSA:3.40.50.300 1066 1100 0.0034 T 29-03-2018 THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 Gene3D G3DSA:1.20.1580.10 104 483 4.6E-82 T 29-03-2018 THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 SUPERFAMILY SSF52540 1036 1230 2.18E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 SUPERFAMILY SSF52540 1362 1501 2.18E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 Gene3D G3DSA:3.40.50.300 606 948 1.1E-47 T 29-03-2018 THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 SUPERFAMILY SSF52540 1550 1596 2.71E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 SUPERFAMILY SSF52540 1642 1883 2.71E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 13 939 8.4E-280 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 Gene3D G3DSA:3.40.50.300 949 1055 0.06 T 29-03-2018 THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 Gene3D G3DSA:3.40.50.300 1056 1065 0.42 T 29-03-2018 THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 Gene3D G3DSA:3.40.50.300 1545 1909 3.8E-50 T 29-03-2018 THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 SUPERFAMILY SSF52540 15 214 1.58E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 SUPERFAMILY SSF52540 434 565 1.58E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 Gene3D G3DSA:3.40.50.300 41 103 0.15 T 29-03-2018 THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 SMART SM00382 1049 1496 1.0 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 SMART SM00382 629 920 0.2 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 SMART SM00382 1567 1876 0.36 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 ProSitePatterns PS00211 ABC transporters family signature. 1793 1807 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS16940 53bca8ab259e6a4c818c95292e1378fd 1913 Gene3D G3DSA:3.40.1140.10 10 40 1.4E-6 T 29-03-2018 THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 Gene3D G3DSA:1.10.510.10 90 299 9.9E-32 T 29-03-2018 THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 Gene3D G3DSA:3.30.450.40 1315 1472 2.3E-21 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 SUPERFAMILY SSF55073 1489 1646 1.26E-43 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 SMART SM00267 1473 1648 4.5E-62 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 Gene3D G3DSA:3.40.50.300 300 508 6.6E-10 T 29-03-2018 THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 Gene3D G3DSA:1.25.40.10 549 1314 9.7E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 SUPERFAMILY SSF52540 278 374 1.33E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 SUPERFAMILY SSF52540 427 494 1.33E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1485 1644 4.0E-45 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 Pfam PF00069 Protein kinase domain 100 259 1.6E-17 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 SUPERFAMILY SSF55781 1296 1468 1.66E-21 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 SMART SM00220 2 261 5.2E-10 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 Gene3D G3DSA:3.30.70.270 1479 1651 5.4E-49 T 29-03-2018 THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1480 1646 3.5E-48 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 Pfam PF01590 GAF domain 1311 1453 2.7E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 SUPERFAMILY SSF56112 15 258 5.68E-32 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 SMART SM00065 1310 1463 6.4E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS26755 8621ac97418c2b53c9aa222b51ccd563 1652 Pfam PF13191 AAA ATPase domain 292 484 2.9E-36 T 29-03-2018 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 SUPERFAMILY SSF100934 526 636 3.14E-25 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 354 368 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 Gene3D G3DSA:3.30.420.40 320 379 3.6E-14 T 29-03-2018 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 637 1.0E-253 T 29-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 Gene3D G3DSA:2.60.34.10 409 550 3.0E-47 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 SUPERFAMILY SSF100920 406 557 1.31E-47 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 SUPERFAMILY SSF53067 19 198 6.11E-51 T 29-03-2018 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 Gene3D G3DSA:1.20.1270.10 551 638 4.7E-9 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 PRINTS PR00301 70kDa heat shock protein signature 48 60 9.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 PRINTS PR00301 70kDa heat shock protein signature 153 173 9.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 PRINTS PR00301 70kDa heat shock protein signature 20 33 9.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 PRINTS PR00301 70kDa heat shock protein signature 351 367 9.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 PRINTS PR00301 70kDa heat shock protein signature 407 426 9.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 PRINTS PR00301 70kDa heat shock protein signature 488 504 9.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 PRINTS PR00301 70kDa heat shock protein signature 212 222 9.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 PRINTS PR00301 70kDa heat shock protein signature 382 402 9.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 Pfam PF00012 Hsp70 protein 22 621 7.0E-179 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 SUPERFAMILY SSF53067 203 398 4.25E-52 T 29-03-2018 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 206 219 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 639 41.557 T 29-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 Gene3D G3DSA:3.90.640.10 251 319 9.1E-14 T 29-03-2018 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 Gene3D G3DSA:3.30.420.40 208 250 4.8E-16 T 29-03-2018 THSYN_RS26555 09d6301fb45afa5341e0e974f753fce4 646 Gene3D G3DSA:3.30.420.40 20 207 9.0E-56 T 29-03-2018 THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 Gene3D G3DSA:3.30.450.20 30 177 2.4E-24 T 29-03-2018 THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 SMART SM00387 364 475 8.5E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 Pfam PF00672 HAMP domain 205 246 1.6E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 369 473 3.3E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 SMART SM00388 255 320 8.1E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 472 1.0E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 415 1.0E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 453 1.0E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 429 1.0E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 Gene3D G3DSA:1.10.287.130 233 316 4.1E-11 T 29-03-2018 THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 Gene3D G3DSA:3.30.565.10 324 477 2.6E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 Pfam PF00512 His Kinase A (phospho-acceptor) domain 263 319 2.9E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 SUPERFAMILY SSF103190 67 177 5.1E-11 T 29-03-2018 IPR029151 Periplasmic sensor domain-like THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 SUPERFAMILY SSF47384 255 319 1.24E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS28705 d3a635975ffba3fa7833d0704939fec3 477 SUPERFAMILY SSF55874 310 473 9.04E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS13660 a2954e1f14921fae2c0356d64202ae47 340 SUPERFAMILY SSF102114 107 328 2.22E-22 T 29-03-2018 THSYN_RS13660 a2954e1f14921fae2c0356d64202ae47 340 TIGRFAM TIGR03821 EFP_modif_epmB: EF-P beta-lysylation protein EpmB 19 338 4.9E-122 T 29-03-2018 IPR022462 Lysine-2,3-aminomutase-like THSYN_RS13660 a2954e1f14921fae2c0356d64202ae47 340 PIRSF PIRSF004911 1 340 1.5E-102 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase THSYN_RS13660 a2954e1f14921fae2c0356d64202ae47 340 Gene3D G3DSA:3.20.20.70 108 325 6.9E-14 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS13660 a2954e1f14921fae2c0356d64202ae47 340 TIGRFAM TIGR00238 TIGR00238: KamA family protein 50 332 4.5E-85 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase THSYN_RS26265 3231a37bc586d598ddeceb5b672a5c63 171 Gene3D G3DSA:1.10.940.10 10 168 1.4E-31 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THSYN_RS26265 3231a37bc586d598ddeceb5b672a5c63 171 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 14 163 4.4E-31 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 THSYN_RS26265 3231a37bc586d598ddeceb5b672a5c63 171 SUPERFAMILY SSF48013 12 163 1.44E-31 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THSYN_RS26265 3231a37bc586d598ddeceb5b672a5c63 171 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 12 165 19.026 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 THSYN_RS26265 3231a37bc586d598ddeceb5b672a5c63 171 Pfam PF01029 NusB family 16 162 3.4E-26 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THSYN_RS01225 340820ab0eb07da1020604db01fa412d 326 SUPERFAMILY SSF53448 70 261 1.1E-5 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS01225 340820ab0eb07da1020604db01fa412d 326 Gene3D G3DSA:3.90.550.10 63 307 7.7E-8 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS20330 140ef6920c5f2e36f84012246adf2828 348 Gene3D G3DSA:3.40.630.10 29 310 4.8E-12 T 29-03-2018 THSYN_RS20330 140ef6920c5f2e36f84012246adf2828 348 SUPERFAMILY SSF53187 17 310 3.81E-39 T 29-03-2018 THSYN_RS20330 140ef6920c5f2e36f84012246adf2828 348 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 46 218 1.7E-8 T 29-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 THSYN_RS00760 40fbccc611634f181bc3f64fa7145e4e 81 SUPERFAMILY SSF143120 5 43 8.5E-8 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS00760 40fbccc611634f181bc3f64fa7145e4e 81 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 10 43 3.4E-7 T 29-03-2018 THSYN_RS00760 40fbccc611634f181bc3f64fa7145e4e 81 Gene3D G3DSA:3.40.1620.10 3 41 7.2E-12 T 29-03-2018 THSYN_RS00760 40fbccc611634f181bc3f64fa7145e4e 81 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 43 2.1E-7 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 SUPERFAMILY SSF55874 498 669 4.32E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 556 669 3.1E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 SMART SM00086 371 413 3.1E-4 T 29-03-2018 IPR001610 PAC motif THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 Gene3D G3DSA:3.30.565.10 513 681 1.8E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 SMART SM00387 556 672 3.3E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 Pfam PF00512 His Kinase A (phospho-acceptor) domain 444 509 2.1E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 SUPERFAMILY SSF52172 697 817 3.27E-37 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 Gene3D G3DSA:1.20.120.160 859 1034 3.4E-12 T 29-03-2018 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 SUPERFAMILY SSF55785 290 411 2.79E-20 T 29-03-2018 IPR000014 PAS domain THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 SUPERFAMILY SSF47384 428 510 3.73E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 Pfam PF00072 Response regulator receiver domain 700 812 1.7E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 Pfam PF01627 Hpt domain 868 950 3.6E-6 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 Gene3D G3DSA:3.30.450.20 267 431 9.3E-26 T 29-03-2018 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 Pfam PF08448 PAS fold 306 415 8.8E-16 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 SUPERFAMILY SSF47226 796 808 5.63E-13 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 SUPERFAMILY SSF47226 847 939 5.63E-13 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 PRINTS PR00344 Bacterial sensor protein C-terminal signature 632 650 2.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 PRINTS PR00344 Bacterial sensor protein C-terminal signature 597 611 2.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 PRINTS PR00344 Bacterial sensor protein C-terminal signature 615 625 2.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 PRINTS PR00344 Bacterial sensor protein C-terminal signature 656 669 2.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 SMART SM00388 444 509 4.2E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 Pfam PF05227 CHASE3 domain 98 229 1.5E-21 T 29-03-2018 IPR007891 CHASE3 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 Gene3D G3DSA:3.40.50.2300 684 818 9.7E-39 T 29-03-2018 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 Gene3D G3DSA:1.10.287.130 435 505 1.0E-17 T 29-03-2018 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 SMART SM00448 697 812 1.2E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS01435 4aeaa9ff8d850abd85233609ae3ba92f 1034 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 296 419 9.3E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 Pfam PF08448 PAS fold 23 117 3.4E-5 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 Pfam PF02954 Bacterial regulatory protein, Fis family 421 458 3.7E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 SUPERFAMILY SSF55785 19 111 1.26E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 SUPERFAMILY SSF46689 382 460 1.12E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 SUPERFAMILY SSF55785 265 379 9.77E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 SUPERFAMILY SSF55785 142 248 1.58E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 Gene3D G3DSA:1.10.10.60 401 463 2.3E-14 T 29-03-2018 THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 Gene3D G3DSA:3.30.450.20 147 255 2.8E-17 T 29-03-2018 THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 Gene3D G3DSA:3.30.450.20 267 382 1.4E-9 T 29-03-2018 THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 TIGRFAM TIGR02040 PpsR-CrtJ: transcriptional regulator PpsR 19 460 2.8E-148 T 29-03-2018 IPR011785 Transcription regulator PpsR THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 Pfam PF13188 PAS domain 276 304 0.0075 T 29-03-2018 IPR000014 PAS domain THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 Pfam PF13188 PAS domain 151 210 1.3E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 146 238 4.4E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 424 441 5.5E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 441 461 5.5E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 SMART SM00091 150 217 8.2E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 SMART SM00091 14 80 6.7 T 29-03-2018 IPR000014 PAS domain THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 SMART SM00091 271 340 0.0068 T 29-03-2018 IPR000014 PAS domain THSYN_RS31705 e47c9434a0b0b0ebce74a779fac9abc2 469 Gene3D G3DSA:3.30.450.20 16 146 4.7E-8 T 29-03-2018 THSYN_RS25845 72160f3dd3f1fdb13ee1df0527589d3c 539 Gene3D G3DSA:3.40.50.1820 170 511 8.9E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS25845 72160f3dd3f1fdb13ee1df0527589d3c 539 SUPERFAMILY SSF53474 173 464 1.02E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS25845 72160f3dd3f1fdb13ee1df0527589d3c 539 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 50 216 1.9E-57 T 29-03-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 THSYN_RS08220 82bd340d9d079faaa6045438a2c91fb2 262 Pfam PF01590 GAF domain 22 168 8.1E-14 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS08220 82bd340d9d079faaa6045438a2c91fb2 262 SUPERFAMILY SSF55781 5 188 2.18E-23 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS08220 82bd340d9d079faaa6045438a2c91fb2 262 SMART SM00065 21 178 2.5E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS08220 82bd340d9d079faaa6045438a2c91fb2 262 Gene3D G3DSA:3.30.450.40 6 196 8.7E-22 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS28215 923fe21b0df0ef2e6eab34ea39c4f6f1 424 Gene3D G3DSA:2.160.10.10 283 408 4.9E-13 T 29-03-2018 THSYN_RS28215 923fe21b0df0ef2e6eab34ea39c4f6f1 424 Pfam PF00483 Nucleotidyl transferase 13 280 1.9E-59 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THSYN_RS28215 923fe21b0df0ef2e6eab34ea39c4f6f1 424 SUPERFAMILY SSF51161 257 384 2.06E-13 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS28215 923fe21b0df0ef2e6eab34ea39c4f6f1 424 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 201 211 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 THSYN_RS28215 923fe21b0df0ef2e6eab34ea39c4f6f1 424 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 17 36 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 THSYN_RS28215 923fe21b0df0ef2e6eab34ea39c4f6f1 424 SUPERFAMILY SSF53448 346 361 4.69E-70 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS28215 923fe21b0df0ef2e6eab34ea39c4f6f1 424 SUPERFAMILY SSF53448 10 284 4.69E-70 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS28215 923fe21b0df0ef2e6eab34ea39c4f6f1 424 Gene3D G3DSA:3.90.550.10 1 282 1.7E-55 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS28215 923fe21b0df0ef2e6eab34ea39c4f6f1 424 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 103 111 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 THSYN_RS23605 e78f8fbb12fd1287d500053ff8619d71 1131 SUPERFAMILY SSF54001 8 337 2.1E-69 T 29-03-2018 THSYN_RS23605 e78f8fbb12fd1287d500053ff8619d71 1131 Pfam PF01841 Transglutaminase-like superfamily 133 246 4.7E-17 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS23605 e78f8fbb12fd1287d500053ff8619d71 1131 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 276 1126 0.0 T 29-03-2018 IPR018667 Domain of unknown function DUF2126 THSYN_RS23605 e78f8fbb12fd1287d500053ff8619d71 1131 Gene3D G3DSA:3.90.260.10 166 286 7.0E-8 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS23605 e78f8fbb12fd1287d500053ff8619d71 1131 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 83 7.3E-29 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal THSYN_RS23605 e78f8fbb12fd1287d500053ff8619d71 1131 SMART SM00460 172 248 5.0E-18 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS03285 81ff21e0460d6787f88cfa13586c6612 199 Pfam PF00186 Dihydrofolate reductase 10 167 2.2E-56 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 THSYN_RS03285 81ff21e0460d6787f88cfa13586c6612 199 PRINTS PR00070 Dihydrofolate reductase signature 48 59 1.3E-15 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 THSYN_RS03285 81ff21e0460d6787f88cfa13586c6612 199 PRINTS PR00070 Dihydrofolate reductase signature 99 113 1.3E-15 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 THSYN_RS03285 81ff21e0460d6787f88cfa13586c6612 199 PRINTS PR00070 Dihydrofolate reductase signature 21 31 1.3E-15 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 THSYN_RS03285 81ff21e0460d6787f88cfa13586c6612 199 PRINTS PR00070 Dihydrofolate reductase signature 35 43 1.3E-15 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 THSYN_RS03285 81ff21e0460d6787f88cfa13586c6612 199 PIRSF PIRSF000194 5 169 6.4E-61 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 THSYN_RS03285 81ff21e0460d6787f88cfa13586c6612 199 SUPERFAMILY SSF53597 10 167 2.88E-51 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 THSYN_RS03285 81ff21e0460d6787f88cfa13586c6612 199 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 21 43 - T 29-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 THSYN_RS03285 81ff21e0460d6787f88cfa13586c6612 199 Gene3D G3DSA:3.40.430.10 5 170 6.1E-49 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 THSYN_RS18520 84902c8b904778c3d9f2006d43844778 336 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 333 4.0E-145 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 THSYN_RS18520 84902c8b904778c3d9f2006d43844778 336 Gene3D G3DSA:3.90.25.10 207 251 4.8E-11 T 29-03-2018 THSYN_RS18520 84902c8b904778c3d9f2006d43844778 336 Gene3D G3DSA:3.90.25.10 316 336 0.0091 T 29-03-2018 THSYN_RS18520 84902c8b904778c3d9f2006d43844778 336 Gene3D G3DSA:3.90.25.10 252 315 1.4E-22 T 29-03-2018 THSYN_RS18520 84902c8b904778c3d9f2006d43844778 336 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 5.0E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS18520 84902c8b904778c3d9f2006d43844778 336 SUPERFAMILY SSF51735 1 333 5.38E-102 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS18520 84902c8b904778c3d9f2006d43844778 336 PRINTS PR01713 Nucleotide sugar epimerase signature 294 311 1.3E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 THSYN_RS18520 84902c8b904778c3d9f2006d43844778 336 PRINTS PR01713 Nucleotide sugar epimerase signature 230 245 1.3E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 THSYN_RS18520 84902c8b904778c3d9f2006d43844778 336 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 1.3E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 THSYN_RS18520 84902c8b904778c3d9f2006d43844778 336 PRINTS PR01713 Nucleotide sugar epimerase signature 255 270 1.3E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 THSYN_RS18520 84902c8b904778c3d9f2006d43844778 336 Gene3D G3DSA:3.40.50.720 1 206 1.4E-44 T 29-03-2018 THSYN_RS32155 dc8105765e84b354f2481245372eaf31 317 Gene3D G3DSA:3.30.950.10 133 250 8.6E-52 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS32155 dc8105765e84b354f2481245372eaf31 317 SUPERFAMILY SSF53790 4 256 7.46E-56 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS32155 dc8105765e84b354f2481245372eaf31 317 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 9 220 4.2E-36 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS32155 dc8105765e84b354f2481245372eaf31 317 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 10 252 2.1E-93 T 29-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 THSYN_RS32155 dc8105765e84b354f2481245372eaf31 317 Gene3D G3DSA:3.40.1010.10 7 132 9.3E-33 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS18190 5d94ec3a91eb7b050a6239148845cf21 610 Gene3D G3DSA:3.30.70.1450 321 399 4.0E-14 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS18190 5d94ec3a91eb7b050a6239148845cf21 610 Pfam PF02080 TrkA-C domain 231 293 1.4E-10 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS18190 5d94ec3a91eb7b050a6239148845cf21 610 Pfam PF02080 TrkA-C domain 325 392 3.5E-9 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS18190 5d94ec3a91eb7b050a6239148845cf21 610 Gene3D G3DSA:3.30.70.1450 223 311 1.0E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS18190 5d94ec3a91eb7b050a6239148845cf21 610 Pfam PF03600 Citrate transporter 17 555 3.4E-45 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 THSYN_RS18190 5d94ec3a91eb7b050a6239148845cf21 610 SUPERFAMILY SSF116726 320 394 2.22E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS18190 5d94ec3a91eb7b050a6239148845cf21 610 SUPERFAMILY SSF116726 230 293 8.89E-10 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 494 658 1.5E-50 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 SUPERFAMILY SSF55785 241 363 2.42E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 SMART SM00091 377 446 0.033 T 29-03-2018 IPR000014 PAS domain THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 SMART SM00091 252 318 0.51 T 29-03-2018 IPR000014 PAS domain THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 Gene3D G3DSA:3.30.450.20 241 375 1.5E-20 T 29-03-2018 THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 Gene3D G3DSA:3.30.70.270 491 659 1.3E-58 T 29-03-2018 THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 SUPERFAMILY SSF55785 362 485 3.4E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 Pfam PF00989 PAS fold 254 362 3.6E-5 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 Gene3D G3DSA:3.30.450.20 376 490 3.0E-15 T 29-03-2018 THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 Pfam PF08448 PAS fold 399 489 1.0E-9 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 Pfam PF00990 Diguanylate cyclase, GGDEF domain 498 655 4.2E-45 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 SMART SM00267 487 659 2.1E-63 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 374 494 2.5E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 255 371 8.1E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS04140 cee07dac68f1265cafdbf7c912487b23 663 SUPERFAMILY SSF55073 503 657 7.22E-50 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS16430 d2938e157e9b5982d4357d045d0599ca 221 Gene3D G3DSA:3.40.50.300 1 221 1.2E-63 T 29-03-2018 THSYN_RS16430 d2938e157e9b5982d4357d045d0599ca 221 Pfam PF00005 ABC transporter 25 170 3.8E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS16430 d2938e157e9b5982d4357d045d0599ca 221 SUPERFAMILY SSF52540 6 220 3.03E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16430 d2938e157e9b5982d4357d045d0599ca 221 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS16430 d2938e157e9b5982d4357d045d0599ca 221 SMART SM00382 34 218 1.8E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS31930 d65f39e25a0eab6948bed8e06e6a0429 79 SUPERFAMILY SSF143100 10 60 4.84E-12 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS31930 d65f39e25a0eab6948bed8e06e6a0429 79 Gene3D G3DSA:3.30.2390.10 4 69 1.5E-9 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS09805 3738c38e55bbdfdd6e6ab04478fc828d 379 Pfam PF01420 Type I restriction modification DNA specificity domain 3 154 2.0E-15 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS09805 3738c38e55bbdfdd6e6ab04478fc828d 379 Pfam PF01420 Type I restriction modification DNA specificity domain 183 335 6.4E-7 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS09805 3738c38e55bbdfdd6e6ab04478fc828d 379 Gene3D G3DSA:3.90.220.20 149 334 2.3E-22 T 29-03-2018 THSYN_RS09805 3738c38e55bbdfdd6e6ab04478fc828d 379 Gene3D G3DSA:3.90.220.20 1 148 3.1E-19 T 29-03-2018 THSYN_RS09805 3738c38e55bbdfdd6e6ab04478fc828d 379 SUPERFAMILY SSF116734 179 356 2.62E-31 T 29-03-2018 THSYN_RS09805 3738c38e55bbdfdd6e6ab04478fc828d 379 SUPERFAMILY SSF116734 2 166 9.16E-31 T 29-03-2018 THSYN_RS18960 7757f7a33c6d86c3508c758abed15121 101 Pfam PF04358 DsrC like protein 7 101 1.2E-24 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE THSYN_RS18960 7757f7a33c6d86c3508c758abed15121 101 Gene3D G3DSA:3.30.1420.10 6 38 5.0E-13 T 29-03-2018 THSYN_RS18960 7757f7a33c6d86c3508c758abed15121 101 SUPERFAMILY SSF69721 7 101 8.24E-30 T 29-03-2018 IPR025526 DsrC-like domain THSYN_RS18960 7757f7a33c6d86c3508c758abed15121 101 Gene3D G3DSA:1.10.10.370 39 100 2.0E-15 T 29-03-2018 THSYN_RS18960 7757f7a33c6d86c3508c758abed15121 101 PIRSF PIRSF006223 1 101 8.2E-23 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE THSYN_RS18960 7757f7a33c6d86c3508c758abed15121 101 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 7 101 2.1E-21 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE THSYN_RS16245 382b582ca0b953dddd58c313da6d68ec 168 Gene3D G3DSA:1.10.10.10 74 168 6.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS16245 382b582ca0b953dddd58c313da6d68ec 168 SMART SM00862 96 167 2.4E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS16245 382b582ca0b953dddd58c313da6d68ec 168 Pfam PF00072 Response regulator receiver domain 5 62 1.5E-10 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS16245 382b582ca0b953dddd58c313da6d68ec 168 Pfam PF00486 Transcriptional regulatory protein, C terminal 97 167 1.0E-13 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS16245 382b582ca0b953dddd58c313da6d68ec 168 SUPERFAMILY SSF52172 4 66 2.28E-14 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS16245 382b582ca0b953dddd58c313da6d68ec 168 Gene3D G3DSA:3.40.50.2300 2 73 1.2E-13 T 29-03-2018 THSYN_RS16245 382b582ca0b953dddd58c313da6d68ec 168 SUPERFAMILY SSF46894 87 167 1.62E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS07415 4b725372d1fdad2ecd80f941bd860d39 221 SUPERFAMILY SSF52540 46 157 1.81E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07415 4b725372d1fdad2ecd80f941bd860d39 221 Gene3D G3DSA:3.40.50.300 45 158 4.1E-27 T 29-03-2018 THSYN_RS07415 4b725372d1fdad2ecd80f941bd860d39 221 PIRSF PIRSF037290 1 216 9.2E-57 T 29-03-2018 IPR017166 Uncharacterised conserved protein UCP037290 THSYN_RS25160 51f10879add93e2bb64bf6690f95489f 317 Pfam PF00535 Glycosyl transferase family 2 7 125 3.9E-28 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS25160 51f10879add93e2bb64bf6690f95489f 317 SUPERFAMILY SSF53448 4 221 6.75E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS25160 51f10879add93e2bb64bf6690f95489f 317 Gene3D G3DSA:3.90.550.10 1 302 2.4E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS26785 9d3aed599e6758b2fd62d94d887dc0c3 139 Pfam PF00114 Pilin (bacterial filament) 36 138 6.9E-19 T 29-03-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 THSYN_RS26785 9d3aed599e6758b2fd62d94d887dc0c3 139 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 27 2.9E-11 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS26785 9d3aed599e6758b2fd62d94d887dc0c3 139 Gene3D G3DSA:3.30.700.10 8 138 4.8E-30 T 29-03-2018 THSYN_RS26785 9d3aed599e6758b2fd62d94d887dc0c3 139 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 28 1.5E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS26785 9d3aed599e6758b2fd62d94d887dc0c3 139 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS26785 9d3aed599e6758b2fd62d94d887dc0c3 139 SUPERFAMILY SSF54523 8 138 7.32E-26 T 29-03-2018 THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 SMART SM00429 658 751 3.5E-8 T 29-03-2018 IPR002909 IPT domain THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 SMART SM00429 485 567 7.5E-8 T 29-03-2018 IPR002909 IPT domain THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 SMART SM00429 569 655 1.5E-7 T 29-03-2018 IPR002909 IPT domain THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 SMART SM00429 401 483 5.0E-8 T 29-03-2018 IPR002909 IPT domain THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 SMART SM00429 317 399 8.0E-6 T 29-03-2018 IPR002909 IPT domain THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 SUPERFAMILY SSF81296 318 400 5.8E-13 T 29-03-2018 IPR014756 Immunoglobulin E-set THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 SUPERFAMILY SSF81296 485 567 6.28E-15 T 29-03-2018 IPR014756 Immunoglobulin E-set THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 SUPERFAMILY SSF81296 567 655 2.04E-11 T 29-03-2018 IPR014756 Immunoglobulin E-set THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 SUPERFAMILY SSF81296 401 482 1.07E-12 T 29-03-2018 IPR014756 Immunoglobulin E-set THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 Pfam PF01833 IPT/TIG domain 486 566 1.1E-13 T 29-03-2018 IPR002909 IPT domain THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 Pfam PF01833 IPT/TIG domain 570 654 6.5E-12 T 29-03-2018 IPR002909 IPT domain THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 Pfam PF01833 IPT/TIG domain 318 398 2.6E-12 T 29-03-2018 IPR002909 IPT domain THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 Pfam PF01833 IPT/TIG domain 659 750 6.6E-11 T 29-03-2018 IPR002909 IPT domain THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 Pfam PF01833 IPT/TIG domain 402 482 2.5E-13 T 29-03-2018 IPR002909 IPT domain THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 SUPERFAMILY SSF81296 657 752 1.78E-12 T 29-03-2018 IPR014756 Immunoglobulin E-set THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 Gene3D G3DSA:2.60.40.10 659 754 4.2E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 Gene3D G3DSA:2.60.40.10 562 656 1.7E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 Gene3D G3DSA:2.60.40.10 316 398 9.8E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 Gene3D G3DSA:2.60.40.10 400 482 1.1E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS21735 09a3f15e998fe6523aa1ba57243e204f 788 Gene3D G3DSA:2.60.40.10 484 561 1.1E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS28115 dd0842836b51aba23debee422c19b661 648 Pfam PF13193 AMP-binding enzyme C-terminal domain 531 609 3.8E-23 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain THSYN_RS28115 dd0842836b51aba23debee422c19b661 648 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 645 53.821 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 THSYN_RS28115 dd0842836b51aba23debee422c19b661 648 SUPERFAMILY SSF56801 14 641 1.24E-183 T 29-03-2018 THSYN_RS28115 dd0842836b51aba23debee422c19b661 648 Pfam PF00501 AMP-binding enzyme 84 522 1.4E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THSYN_RS28115 dd0842836b51aba23debee422c19b661 648 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 82 1.4E-23 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 THSYN_RS28115 dd0842836b51aba23debee422c19b661 648 Gene3D G3DSA:3.40.50.980 266 427 1.5E-36 T 29-03-2018 THSYN_RS28115 dd0842836b51aba23debee422c19b661 648 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 20 643 0.0 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 THSYN_RS28115 dd0842836b51aba23debee422c19b661 648 ProSitePatterns PS00455 Putative AMP-binding domain signature. 260 271 - T 29-03-2018 IPR020845 AMP-binding, conserved site THSYN_RS28115 dd0842836b51aba23debee422c19b661 648 Gene3D G3DSA:3.30.300.30 518 644 2.7E-24 T 29-03-2018 THSYN_RS28115 dd0842836b51aba23debee422c19b661 648 Gene3D G3DSA:3.40.50.980 75 265 3.0E-56 T 29-03-2018 THSYN_RS28115 dd0842836b51aba23debee422c19b661 648 Gene3D G3DSA:2.30.38.10 428 515 1.1E-10 T 29-03-2018 THSYN_RS07800 9b863c53ae8f89bcab49f73602648379 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site THSYN_RS07800 9b863c53ae8f89bcab49f73602648379 67 PRINTS PR00050 Cold shock protein signature 40 58 2.9E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THSYN_RS07800 9b863c53ae8f89bcab49f73602648379 67 PRINTS PR00050 Cold shock protein signature 4 19 2.9E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THSYN_RS07800 9b863c53ae8f89bcab49f73602648379 67 PRINTS PR00050 Cold shock protein signature 25 34 2.9E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THSYN_RS07800 9b863c53ae8f89bcab49f73602648379 67 PIRSF PIRSF002599 1 67 4.2E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 THSYN_RS07800 9b863c53ae8f89bcab49f73602648379 67 Gene3D G3DSA:2.40.50.140 1 67 1.1E-28 T 29-03-2018 THSYN_RS07800 9b863c53ae8f89bcab49f73602648379 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 8.4E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THSYN_RS07800 9b863c53ae8f89bcab49f73602648379 67 SMART SM00357 3 67 1.3E-30 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 THSYN_RS07800 9b863c53ae8f89bcab49f73602648379 67 SUPERFAMILY SSF50249 1 65 1.82E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS04715 13ef23f716295084dcc108bfb06b99fc 413 Pfam PF11799 impB/mucB/samB family C-terminal domain 245 347 1.4E-18 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 THSYN_RS04715 13ef23f716295084dcc108bfb06b99fc 413 Gene3D G3DSA:3.30.1490.100 244 358 8.5E-29 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 THSYN_RS04715 13ef23f716295084dcc108bfb06b99fc 413 Gene3D G3DSA:3.30.70.270 120 176 3.8E-16 T 29-03-2018 THSYN_RS04715 13ef23f716295084dcc108bfb06b99fc 413 Gene3D G3DSA:3.30.70.270 46 119 7.6E-23 T 29-03-2018 THSYN_RS04715 13ef23f716295084dcc108bfb06b99fc 413 Pfam PF00817 impB/mucB/samB family 12 159 4.4E-47 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 THSYN_RS04715 13ef23f716295084dcc108bfb06b99fc 413 SUPERFAMILY SSF100879 246 343 1.73E-25 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 THSYN_RS04715 13ef23f716295084dcc108bfb06b99fc 413 Gene3D G3DSA:1.10.150.20 177 243 1.4E-15 T 29-03-2018 THSYN_RS04715 13ef23f716295084dcc108bfb06b99fc 413 Hamap MF_01113 DNA polymerase IV [dinB]. 6 356 34.503 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 THSYN_RS04715 13ef23f716295084dcc108bfb06b99fc 413 SUPERFAMILY SSF56672 5 239 1.78E-79 T 29-03-2018 THSYN_RS24300 1453e80a6c3adc4025f5246a339ef3c9 176 PIRSF PIRSF036893 3 175 2.8E-38 T 29-03-2018 IPR022271 Lipocalin, ApoD type THSYN_RS24300 1453e80a6c3adc4025f5246a339ef3c9 176 ProSitePatterns PS00213 Lipocalin signature. 34 45 - T 29-03-2018 IPR022272 Lipocalin family conserved site THSYN_RS24300 1453e80a6c3adc4025f5246a339ef3c9 176 Gene3D G3DSA:2.40.128.20 2 175 1.0E-29 T 29-03-2018 IPR012674 Calycin THSYN_RS24300 1453e80a6c3adc4025f5246a339ef3c9 176 Pfam PF08212 Lipocalin-like domain 33 174 1.3E-36 T 29-03-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain THSYN_RS24300 1453e80a6c3adc4025f5246a339ef3c9 176 PRINTS PR01171 Bacterial lipocalin signature 104 118 1.9E-7 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 THSYN_RS24300 1453e80a6c3adc4025f5246a339ef3c9 176 PRINTS PR01171 Bacterial lipocalin signature 33 47 1.9E-7 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 THSYN_RS24300 1453e80a6c3adc4025f5246a339ef3c9 176 PRINTS PR01171 Bacterial lipocalin signature 163 173 1.9E-7 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 THSYN_RS24300 1453e80a6c3adc4025f5246a339ef3c9 176 PRINTS PR01171 Bacterial lipocalin signature 50 66 1.9E-7 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 THSYN_RS24300 1453e80a6c3adc4025f5246a339ef3c9 176 PRINTS PR01171 Bacterial lipocalin signature 136 147 1.9E-7 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 THSYN_RS24300 1453e80a6c3adc4025f5246a339ef3c9 176 SUPERFAMILY SSF50814 8 174 1.71E-37 T 29-03-2018 IPR012674 Calycin THSYN_RS05690 345f483b782331f1a793fa103a8a51a1 125 PRINTS PR01650 Bacterial translocase SecE signature 107 123 3.5E-21 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 THSYN_RS05690 345f483b782331f1a793fa103a8a51a1 125 PRINTS PR01650 Bacterial translocase SecE signature 63 83 3.5E-21 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 THSYN_RS05690 345f483b782331f1a793fa103a8a51a1 125 PRINTS PR01650 Bacterial translocase SecE signature 42 63 3.5E-21 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 THSYN_RS05690 345f483b782331f1a793fa103a8a51a1 125 PRINTS PR01650 Bacterial translocase SecE signature 87 107 3.5E-21 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 THSYN_RS05690 345f483b782331f1a793fa103a8a51a1 125 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 68 121 1.6E-16 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 THSYN_RS05690 345f483b782331f1a793fa103a8a51a1 125 Gene3D G3DSA:1.20.5.1030 66 117 2.0E-18 T 29-03-2018 THSYN_RS05690 345f483b782331f1a793fa103a8a51a1 125 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 67 120 1.7E-19 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THSYN_RS05690 345f483b782331f1a793fa103a8a51a1 125 Hamap MF_00422 Protein translocase subunit SecE [secE]. 61 119 11.866 T 29-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THSYN_RS09565 538561e0ad5f4561397a02281938fb76 339 SUPERFAMILY SSF53335 63 276 2.33E-11 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS09565 538561e0ad5f4561397a02281938fb76 339 Gene3D G3DSA:3.40.50.150 132 272 1.5E-5 T 29-03-2018 THSYN_RS09565 538561e0ad5f4561397a02281938fb76 339 Pfam PF13578 Methyltransferase domain 150 250 2.9E-9 T 29-03-2018 THSYN_RS30435 ee7364453a5aeeb09dbddfb002d3baf6 97 TIGRFAM TIGR02762 TraL_TIGR: type IV conjugative transfer system protein TraL 6 96 1.4E-14 T 29-03-2018 IPR009838 Type IV conjugative transfer system, protein TraL GO:0000746|GO:0019867 THSYN_RS30435 ee7364453a5aeeb09dbddfb002d3baf6 97 Pfam PF07178 TraL protein 6 95 5.4E-24 T 29-03-2018 IPR009838 Type IV conjugative transfer system, protein TraL GO:0000746|GO:0019867 THSYN_RS23185 7c0c120eb9c582c424c70b23d1cf7c4b 281 SUPERFAMILY SSF52096 18 276 3.13E-76 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS23185 7c0c120eb9c582c424c70b23d1cf7c4b 281 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 12 280 54.082 T 29-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 THSYN_RS23185 7c0c120eb9c582c424c70b23d1cf7c4b 281 TIGRFAM TIGR01929 menB: naphthoate synthase 20 277 7.8E-132 T 29-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 THSYN_RS23185 7c0c120eb9c582c424c70b23d1cf7c4b 281 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 119 139 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THSYN_RS23185 7c0c120eb9c582c424c70b23d1cf7c4b 281 Gene3D G3DSA:3.90.226.10 6 220 5.1E-61 T 29-03-2018 THSYN_RS23185 7c0c120eb9c582c424c70b23d1cf7c4b 281 Pfam PF00378 Enoyl-CoA hydratase/isomerase 29 275 1.3E-77 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THSYN_RS23185 7c0c120eb9c582c424c70b23d1cf7c4b 281 Gene3D G3DSA:1.10.12.10 221 269 1.7E-15 T 29-03-2018 IPR014748 Crontonase, C-terminal THSYN_RS09020 9575b9ea2d30a847c6d0da9c6f8bcff1 301 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 51 275 1.8E-49 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 THSYN_RS09020 9575b9ea2d30a847c6d0da9c6f8bcff1 301 SUPERFAMILY SSF56601 51 292 4.3E-47 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS09020 9575b9ea2d30a847c6d0da9c6f8bcff1 301 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 158 171 8.2E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THSYN_RS09020 9575b9ea2d30a847c6d0da9c6f8bcff1 301 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 130 147 8.2E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THSYN_RS09020 9575b9ea2d30a847c6d0da9c6f8bcff1 301 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 78 89 8.2E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THSYN_RS09020 9575b9ea2d30a847c6d0da9c6f8bcff1 301 Gene3D G3DSA:3.40.710.10 7 296 3.8E-40 T 29-03-2018 THSYN_RS08065 a47080288bc14943dcaa80397e885e86 271 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 4 267 2.7E-97 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS08065 a47080288bc14943dcaa80397e885e86 271 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 267 34.502 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS08065 a47080288bc14943dcaa80397e885e86 271 SUPERFAMILY SSF51735 238 269 6.35E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS08065 a47080288bc14943dcaa80397e885e86 271 SUPERFAMILY SSF51735 3 128 6.35E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS08065 a47080288bc14943dcaa80397e885e86 271 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 127 2.0E-38 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS08065 a47080288bc14943dcaa80397e885e86 271 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 130 266 4.0E-42 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS08065 a47080288bc14943dcaa80397e885e86 271 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 152 169 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS08065 a47080288bc14943dcaa80397e885e86 271 Gene3D G3DSA:3.40.50.720 1 123 3.3E-27 T 29-03-2018 THSYN_RS08065 a47080288bc14943dcaa80397e885e86 271 PIRSF PIRSF000161 2 270 6.7E-84 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS08065 a47080288bc14943dcaa80397e885e86 271 SUPERFAMILY SSF55347 129 238 1.72E-36 T 29-03-2018 THSYN_RS08065 a47080288bc14943dcaa80397e885e86 271 Gene3D G3DSA:3.30.360.10 128 236 3.3E-35 T 29-03-2018 THSYN_RS22025 a379f5cd7f4239eaa5517d56feb6b080 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 185 8.1E-71 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 THSYN_RS22025 a379f5cd7f4239eaa5517d56feb6b080 185 Pfam PF01765 Ribosome recycling factor 21 183 5.0E-64 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 THSYN_RS22025 a379f5cd7f4239eaa5517d56feb6b080 185 SUPERFAMILY SSF55194 2 183 1.05E-70 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 THSYN_RS22025 a379f5cd7f4239eaa5517d56feb6b080 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.084 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 THSYN_RS22025 a379f5cd7f4239eaa5517d56feb6b080 185 Gene3D G3DSA:1.10.132.20 2 73 1.1E-11 T 29-03-2018 THSYN_RS22025 a379f5cd7f4239eaa5517d56feb6b080 185 Gene3D G3DSA:1.10.132.20 74 184 6.2E-38 T 29-03-2018 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 Hamap MF_00974 DNA primase [dnaG]. 4 576 28.462 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 Pfam PF13155 Toprim-like 260 345 1.1E-13 T 29-03-2018 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 Pfam PF08275 DNA primase catalytic core, N-terminal domain 124 248 5.8E-41 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 Gene3D G3DSA:3.90.580.10 1 103 3.8E-33 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 Gene3D G3DSA:3.40.1360.10 238 364 1.8E-28 T 29-03-2018 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 SUPERFAMILY SSF57783 4 99 2.72E-34 T 29-03-2018 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 Pfam PF10410 DnaB-helicase binding domain of primase 366 419 9.5E-12 T 29-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 SUPERFAMILY SSF56731 113 418 4.19E-105 T 29-03-2018 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 Gene3D G3DSA:1.10.860.10 432 579 1.2E-17 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 Gene3D G3DSA:1.20.50.20 365 414 5.8E-19 T 29-03-2018 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 Gene3D G3DSA:3.90.980.10 108 237 2.9E-46 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 SMART SM00493 256 327 8.0E-19 T 29-03-2018 IPR006171 TOPRIM domain THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 Pfam PF08278 DNA primase DnaG DnaB-binding 446 567 1.6E-16 T 29-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 TIGRFAM TIGR01391 dnaG: DNA primase 4 411 3.8E-139 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 SUPERFAMILY SSF117023 442 563 1.14E-15 T 29-03-2018 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 SMART SM00400 36 90 1.4E-32 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 SMART SM00766 444 572 0.001 T 29-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 THSYN_RS20970 449c355824b3446e666d781c0e7e0770 580 Pfam PF01807 CHC2 zinc finger 6 100 2.3E-37 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 THSYN_RS14990 a168313f3ac45ab58b293b26e24ba1f9 533 Pfam PF03050 Transposase IS66 family 227 487 1.0E-46 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS08670 a168313f3ac45ab58b293b26e24ba1f9 533 Pfam PF03050 Transposase IS66 family 227 487 1.0E-46 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS32265 a168313f3ac45ab58b293b26e24ba1f9 533 Pfam PF03050 Transposase IS66 family 227 487 1.0E-46 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS24390 0619b5ff0f38758ea71b5669f6e59473 429 Pfam PF00589 Phage integrase family 237 382 4.4E-14 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS24390 0619b5ff0f38758ea71b5669f6e59473 429 Gene3D G3DSA:1.10.150.130 111 226 9.3E-22 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS24390 0619b5ff0f38758ea71b5669f6e59473 429 Gene3D G3DSA:1.10.443.10 227 393 1.5E-24 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS24390 0619b5ff0f38758ea71b5669f6e59473 429 SUPERFAMILY SSF56349 115 403 1.56E-55 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS24390 0619b5ff0f38758ea71b5669f6e59473 429 Pfam PF13356 Arm DNA-binding domain 12 102 7.3E-18 T 29-03-2018 IPR025166 Integrase, DNA-binding domain THSYN_RS00155 48191325fe2446ca10c35b0b4facb10c 568 SUPERFAMILY SSF52540 166 564 3.24E-99 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00155 48191325fe2446ca10c35b0b4facb10c 568 SMART SM00382 317 438 5.0E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS00155 48191325fe2446ca10c35b0b4facb10c 568 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 89 564 4.7E-200 T 29-03-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 THSYN_RS00155 48191325fe2446ca10c35b0b4facb10c 568 Gene3D G3DSA:3.40.50.300 290 568 2.2E-67 T 29-03-2018 THSYN_RS00155 48191325fe2446ca10c35b0b4facb10c 568 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 49 154 5.1E-19 T 29-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 THSYN_RS00155 48191325fe2446ca10c35b0b4facb10c 568 Pfam PF00437 Type II/IV secretion system protein 191 456 7.5E-84 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THSYN_RS00155 48191325fe2446ca10c35b0b4facb10c 568 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 384 398 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THSYN_RS00155 48191325fe2446ca10c35b0b4facb10c 568 SUPERFAMILY SSF160246 14 150 1.96E-29 T 29-03-2018 THSYN_RS00155 48191325fe2446ca10c35b0b4facb10c 568 Gene3D G3DSA:3.30.450.90 159 289 2.3E-48 T 29-03-2018 THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 SUPERFAMILY SSF117074 88 187 1.1E-16 T 29-03-2018 THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 SUPERFAMILY SSF117074 891 985 9.68E-17 T 29-03-2018 THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 SUPERFAMILY SSF117074 1050 1142 8.76E-15 T 29-03-2018 THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 SUPERFAMILY SSF117074 728 820 2.88E-16 T 29-03-2018 THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Gene3D G3DSA:2.60.40.10 910 1068 7.4E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Gene3D G3DSA:2.60.40.10 750 909 1.0E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Gene3D G3DSA:2.60.40.10 269 428 5.5E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Gene3D G3DSA:2.60.40.10 429 585 4.2E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Gene3D G3DSA:2.60.40.10 588 749 2.9E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Gene3D G3DSA:2.60.40.10 1069 1282 4.3E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Gene3D G3DSA:2.60.40.10 1 110 0.019 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Gene3D G3DSA:2.60.40.10 111 268 5.4E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 SUPERFAMILY SSF117074 407 500 1.18E-14 T 29-03-2018 THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Pfam PF17210 SdrD B-like domain 271 341 3.4E-12 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Pfam PF17210 SdrD B-like domain 752 854 8.7E-16 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Pfam PF17210 SdrD B-like domain 432 528 1.9E-13 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Pfam PF17210 SdrD B-like domain 592 699 3.4E-13 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Pfam PF17210 SdrD B-like domain 1072 1173 5.5E-12 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Pfam PF17210 SdrD B-like domain 112 186 1.3E-15 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 Pfam PF17210 SdrD B-like domain 912 1014 3.8E-17 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 SUPERFAMILY SSF117074 249 342 4.32E-15 T 29-03-2018 THSYN_RS08395 cd952283f91d3c5c1db40a42c2fa3410 1310 SUPERFAMILY SSF117074 570 660 7.19E-10 T 29-03-2018 THSYN_RS14090 44c14d163f6a7478aed03a33afd91b6b 180 Gene3D G3DSA:3.40.50.300 5 171 2.8E-58 T 29-03-2018 THSYN_RS14090 44c14d163f6a7478aed03a33afd91b6b 180 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 5 169 2.0E-56 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 THSYN_RS14090 44c14d163f6a7478aed03a33afd91b6b 180 PIRSF PIRSF006135 3 173 5.3E-50 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 THSYN_RS14090 44c14d163f6a7478aed03a33afd91b6b 180 SUPERFAMILY SSF52540 5 171 1.27E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS20490 08bccabf0994ed5c7ab4981ed9bb7eec 489 SUPERFAMILY SSF54106 374 419 2.22E-8 T 29-03-2018 IPR018392 LysM domain THSYN_RS20490 08bccabf0994ed5c7ab4981ed9bb7eec 489 Pfam PF01464 Transglycosylase SLT domain 130 228 2.1E-24 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 THSYN_RS20490 08bccabf0994ed5c7ab4981ed9bb7eec 489 SUPERFAMILY SSF54106 436 480 9.55E-10 T 29-03-2018 IPR018392 LysM domain THSYN_RS20490 08bccabf0994ed5c7ab4981ed9bb7eec 489 Gene3D G3DSA:3.10.350.10 360 434 1.8E-11 T 29-03-2018 THSYN_RS20490 08bccabf0994ed5c7ab4981ed9bb7eec 489 SMART SM00257 375 419 5.2E-5 T 29-03-2018 IPR018392 LysM domain THSYN_RS20490 08bccabf0994ed5c7ab4981ed9bb7eec 489 SMART SM00257 437 480 4.0E-6 T 29-03-2018 IPR018392 LysM domain THSYN_RS20490 08bccabf0994ed5c7ab4981ed9bb7eec 489 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 138 166 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 THSYN_RS20490 08bccabf0994ed5c7ab4981ed9bb7eec 489 SUPERFAMILY SSF53955 117 261 7.59E-43 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS20490 08bccabf0994ed5c7ab4981ed9bb7eec 489 Gene3D G3DSA:1.10.530.10 80 263 1.2E-36 T 29-03-2018 THSYN_RS20490 08bccabf0994ed5c7ab4981ed9bb7eec 489 Pfam PF01476 LysM domain 376 419 1.3E-7 T 29-03-2018 IPR018392 LysM domain THSYN_RS20490 08bccabf0994ed5c7ab4981ed9bb7eec 489 Pfam PF01476 LysM domain 438 479 5.7E-9 T 29-03-2018 IPR018392 LysM domain THSYN_RS20490 08bccabf0994ed5c7ab4981ed9bb7eec 489 Gene3D G3DSA:3.10.350.10 435 482 6.6E-10 T 29-03-2018 THSYN_RS19680 7afa074b68e2cb1edd13cf2c4cd66f17 500 Gene3D G3DSA:3.30.43.10 5 110 6.2E-27 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THSYN_RS19680 7afa074b68e2cb1edd13cf2c4cd66f17 500 Gene3D G3DSA:3.20.20.140 248 434 0.0011 T 29-03-2018 THSYN_RS19680 7afa074b68e2cb1edd13cf2c4cd66f17 500 Pfam PF01565 FAD binding domain 58 196 4.8E-42 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THSYN_RS19680 7afa074b68e2cb1edd13cf2c4cd66f17 500 Gene3D G3DSA:1.10.45.10 435 472 3.2E-13 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 THSYN_RS19680 7afa074b68e2cb1edd13cf2c4cd66f17 500 SUPERFAMILY SSF55103 206 475 3.6E-75 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THSYN_RS19680 7afa074b68e2cb1edd13cf2c4cd66f17 500 Gene3D G3DSA:3.30.465.10 111 247 1.5E-38 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THSYN_RS19680 7afa074b68e2cb1edd13cf2c4cd66f17 500 Pfam PF02913 FAD linked oxidases, C-terminal domain 233 472 9.0E-67 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THSYN_RS19680 7afa074b68e2cb1edd13cf2c4cd66f17 500 SUPERFAMILY SSF56176 21 233 5.61E-69 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THSYN_RS26445 386ec326b68b2a5e73f47e458b5661d5 138 Gene3D G3DSA:3.30.300.20 23 138 2.1E-31 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta THSYN_RS26445 386ec326b68b2a5e73f47e458b5661d5 138 SUPERFAMILY SSF82784 1 135 1.83E-39 T 29-03-2018 IPR003718 OsmC/Ohr family THSYN_RS26445 386ec326b68b2a5e73f47e458b5661d5 138 Gene3D G3DSA:2.20.25.10 1 22 2.1E-15 T 29-03-2018 THSYN_RS26445 386ec326b68b2a5e73f47e458b5661d5 138 Pfam PF02566 OsmC-like protein 35 129 6.6E-16 T 29-03-2018 IPR003718 OsmC/Ohr family THSYN_RS10430 9216340e118de6b4db7fd811a41f8114 760 Pfam PF00263 Bacterial type II and III secretion system protein 595 754 1.2E-48 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 THSYN_RS10430 9216340e118de6b4db7fd811a41f8114 760 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 699 732 - T 29-03-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 THSYN_RS10430 9216340e118de6b4db7fd811a41f8114 760 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 317 754 3.4E-157 T 29-03-2018 IPR013355 Type IV pilus secretin PilQ THSYN_RS10430 9216340e118de6b4db7fd811a41f8114 760 Pfam PF07660 Secretin and TonB N terminus short domain 343 389 9.7E-12 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THSYN_RS10430 9216340e118de6b4db7fd811a41f8114 760 SMART SM00965 342 390 2.2E-11 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THSYN_RS10430 9216340e118de6b4db7fd811a41f8114 760 Pfam PF11741 AMIN domain 61 144 5.7E-10 T 29-03-2018 IPR021731 AMIN domain THSYN_RS10430 9216340e118de6b4db7fd811a41f8114 760 PRINTS PR00811 Bacterial general secretion pathway protein D signature 481 491 6.0E-15 T 29-03-2018 IPR001775 GspD/PilQ family THSYN_RS10430 9216340e118de6b4db7fd811a41f8114 760 PRINTS PR00811 Bacterial general secretion pathway protein D signature 718 736 6.0E-15 T 29-03-2018 IPR001775 GspD/PilQ family THSYN_RS10430 9216340e118de6b4db7fd811a41f8114 760 PRINTS PR00811 Bacterial general secretion pathway protein D signature 741 755 6.0E-15 T 29-03-2018 IPR001775 GspD/PilQ family THSYN_RS10430 9216340e118de6b4db7fd811a41f8114 760 PRINTS PR00811 Bacterial general secretion pathway protein D signature 591 615 6.0E-15 T 29-03-2018 IPR001775 GspD/PilQ family THSYN_RS10430 9216340e118de6b4db7fd811a41f8114 760 Pfam PF03958 Bacterial type II/III secretion system short domain 416 481 1.1E-12 T 29-03-2018 IPR005644 NolW-like THSYN_RS02980 5f9080b54d4ca3f0625db09a8102da04 246 SUPERFAMILY SSF53335 38 219 3.56E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02980 5f9080b54d4ca3f0625db09a8102da04 246 Pfam PF13649 Methyltransferase domain 56 163 3.7E-9 T 29-03-2018 THSYN_RS02980 5f9080b54d4ca3f0625db09a8102da04 246 Gene3D G3DSA:3.40.50.150 5 230 2.3E-20 T 29-03-2018 THSYN_RS22815 1f6bc1f7d8496298c8b53df94bd00ae1 179 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 15 162 2.2E-31 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS22815 1f6bc1f7d8496298c8b53df94bd00ae1 179 SUPERFAMILY SSF56770 3 176 2.49E-38 T 29-03-2018 THSYN_RS22815 1f6bc1f7d8496298c8b53df94bd00ae1 179 Gene3D G3DSA:3.40.50.700 1 179 3.3E-38 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS05615 117db2820b9a8827feb1c6e2237ce61b 1068 Pfam PF11867 Domain of unknown function (DUF3387) 724 1063 1.3E-116 T 29-03-2018 IPR021810 Protein of unknown function DUF3387 THSYN_RS05615 117db2820b9a8827feb1c6e2237ce61b 1068 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 309 724 9.3E-126 T 29-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 THSYN_RS05615 117db2820b9a8827feb1c6e2237ce61b 1068 SUPERFAMILY SSF52540 227 508 6.05E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05615 117db2820b9a8827feb1c6e2237ce61b 1068 SUPERFAMILY SSF52540 628 709 7.3E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05615 117db2820b9a8827feb1c6e2237ce61b 1068 SUPERFAMILY SSF52540 424 504 7.3E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05615 117db2820b9a8827feb1c6e2237ce61b 1068 SUPERFAMILY SSF52540 556 598 7.3E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05615 117db2820b9a8827feb1c6e2237ce61b 1068 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 3 211 6.7E-41 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THSYN_RS05615 117db2820b9a8827feb1c6e2237ce61b 1068 Pfam PF04851 Type III restriction enzyme, res subunit 312 472 4.5E-16 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS05615 117db2820b9a8827feb1c6e2237ce61b 1068 SMART SM00487 268 505 1.2E-11 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS05615 117db2820b9a8827feb1c6e2237ce61b 1068 Gene3D G3DSA:3.40.50.300 5 494 1.5E-25 T 29-03-2018 THSYN_RS28880 b0574dc3d9e83032b0170642483dd49f 146 SUPERFAMILY SSF52980 7 139 5.36E-46 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS28880 b0574dc3d9e83032b0170642483dd49f 146 Pfam PF04480 Protein of unknown function (DUF559) 97 137 4.3E-5 T 29-03-2018 IPR007569 Domain of unknown function DUF559 THSYN_RS28880 b0574dc3d9e83032b0170642483dd49f 146 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 7 121 1.4E-41 T 29-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 THSYN_RS28880 b0574dc3d9e83032b0170642483dd49f 146 PIRSF PIRSF018267 6 145 2.8E-46 T 29-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 THSYN_RS28880 b0574dc3d9e83032b0170642483dd49f 146 Gene3D G3DSA:3.40.960.10 26 145 2.1E-30 T 29-03-2018 THSYN_RS28880 b0574dc3d9e83032b0170642483dd49f 146 Pfam PF03852 DNA mismatch endonuclease Vsr 7 74 8.8E-27 T 29-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 THSYN_RS22790 d9791c25b1378319eb989059e8546eee 271 SUPERFAMILY SSF53448 10 221 8.13E-27 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22790 d9791c25b1378319eb989059e8546eee 271 Gene3D G3DSA:3.90.550.10 2 228 1.6E-22 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22790 d9791c25b1378319eb989059e8546eee 271 Pfam PF00535 Glycosyl transferase family 2 14 145 3.7E-13 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS19520 a31661585dadcbcfd13722f3f81e72da 70 Gene3D G3DSA:3.30.2390.10 3 66 1.4E-7 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS19520 a31661585dadcbcfd13722f3f81e72da 70 SUPERFAMILY SSF143100 6 52 6.93E-10 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 SUPERFAMILY SSF140356 34 134 1.19E-33 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 Hamap MF_00347 Polyphosphate kinase [ppk]. 35 710 26.698 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 SUPERFAMILY SSF56024 529 710 1.39E-63 T 29-03-2018 THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 SUPERFAMILY SSF143724 139 339 2.35E-55 T 29-03-2018 THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 Gene3D G3DSA:3.30.870.10 529 715 1.2E-37 T 29-03-2018 THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 Pfam PF13090 Polyphosphate kinase C-terminal domain 358 705 6.3E-141 T 29-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 SUPERFAMILY SSF56024 349 523 2.12E-49 T 29-03-2018 THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 Pfam PF02503 Polyphosphate kinase middle domain 154 349 5.4E-57 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 Gene3D G3DSA:3.30.870.10 347 528 1.5E-16 T 29-03-2018 THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 Pfam PF13089 Polyphosphate kinase N-terminal domain 37 141 5.3E-34 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 PIRSF PIRSF015589 18 724 1.0E-265 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 Gene3D G3DSA:3.30.1840.10 141 334 4.1E-57 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 Gene3D G3DSA:1.20.58.310 39 140 5.5E-32 T 29-03-2018 THSYN_RS26270 61c64daf7899eee3ed4b6bcf1b2f659f 739 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 37 706 1.3E-227 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 THSYN_RS20500 b0e6b7b7cb7dbdd2a2a3a121962079c9 587 SUPERFAMILY SSF102114 174 409 1.57E-29 T 29-03-2018 THSYN_RS20500 b0e6b7b7cb7dbdd2a2a3a121962079c9 587 SMART SM00729 203 417 2.2E-16 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS20500 b0e6b7b7cb7dbdd2a2a3a121962079c9 587 Gene3D G3DSA:3.20.20.70 192 459 1.9E-31 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS20500 b0e6b7b7cb7dbdd2a2a3a121962079c9 587 Gene3D G3DSA:3.40.50.280 37 168 2.6E-4 T 29-03-2018 THSYN_RS20500 b0e6b7b7cb7dbdd2a2a3a121962079c9 587 Pfam PF04055 Radical SAM superfamily 210 368 7.0E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS00135 1ff6bde7bbe9b479977a71c3ce06cb16 479 SUPERFAMILY SSF50156 134 229 1.14E-20 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS00135 1ff6bde7bbe9b479977a71c3ce06cb16 479 SMART SM00228 146 217 3.5E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS00135 1ff6bde7bbe9b479977a71c3ce06cb16 479 Pfam PF13180 PDZ domain 146 226 9.4E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS00135 1ff6bde7bbe9b479977a71c3ce06cb16 479 Gene3D G3DSA:2.30.42.10 153 219 2.3E-17 T 29-03-2018 THSYN_RS00135 1ff6bde7bbe9b479977a71c3ce06cb16 479 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 99 422 2.2E-106 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 THSYN_RS00135 1ff6bde7bbe9b479977a71c3ce06cb16 479 SUPERFAMILY SSF52096 238 415 5.3E-81 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS00135 1ff6bde7bbe9b479977a71c3ce06cb16 479 SUPERFAMILY SSF52096 80 164 5.3E-81 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS00135 1ff6bde7bbe9b479977a71c3ce06cb16 479 Pfam PF03572 Peptidase family S41 245 409 1.9E-56 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 THSYN_RS00135 1ff6bde7bbe9b479977a71c3ce06cb16 479 Gene3D G3DSA:3.90.226.10 220 469 5.7E-68 T 29-03-2018 THSYN_RS00135 1ff6bde7bbe9b479977a71c3ce06cb16 479 SMART SM00245 219 411 4.5E-74 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 THSYN_RS00135 1ff6bde7bbe9b479977a71c3ce06cb16 479 Gene3D G3DSA:3.30.750.44 84 152 1.4E-15 T 29-03-2018 THSYN_RS25120 6af7bfd94e2038811f9a3074560b7e07 349 Pfam PF00535 Glycosyl transferase family 2 20 127 4.2E-23 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS25120 6af7bfd94e2038811f9a3074560b7e07 349 Gene3D G3DSA:3.90.550.10 2 301 1.1E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS25120 6af7bfd94e2038811f9a3074560b7e07 349 SUPERFAMILY SSF53448 17 247 4.5E-42 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS05475 295a26592a4ce9fa3684c44c7674ca1a 223 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 18 222 23.952 T 29-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 THSYN_RS05475 295a26592a4ce9fa3684c44c7674ca1a 223 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 51 211 8.5E-43 T 29-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like THSYN_RS05475 295a26592a4ce9fa3684c44c7674ca1a 223 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 24 214 1.1E-17 T 29-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 THSYN_RS05475 295a26592a4ce9fa3684c44c7674ca1a 223 Gene3D G3DSA:2.50.20.10 36 218 8.3E-32 T 29-03-2018 THSYN_RS05475 295a26592a4ce9fa3684c44c7674ca1a 223 SUPERFAMILY SSF89392 42 212 1.1E-35 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX THSYN_RS27320 01251ddf4831ca3fc331cb4517ea6797 346 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 71 91 2.9E-22 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS27320 01251ddf4831ca3fc331cb4517ea6797 346 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 295 313 2.9E-22 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS27320 01251ddf4831ca3fc331cb4517ea6797 346 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 25 39 2.9E-22 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS27320 01251ddf4831ca3fc331cb4517ea6797 346 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 276 293 2.9E-22 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS27320 01251ddf4831ca3fc331cb4517ea6797 346 Gene3D G3DSA:3.40.50.150 2 343 9.1E-39 T 29-03-2018 THSYN_RS27320 01251ddf4831ca3fc331cb4517ea6797 346 SUPERFAMILY SSF53335 167 337 1.4E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS27320 01251ddf4831ca3fc331cb4517ea6797 346 SUPERFAMILY SSF53335 8 94 1.4E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS27320 01251ddf4831ca3fc331cb4517ea6797 346 Pfam PF01555 DNA methylase 26 324 3.0E-32 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THSYN_RS27320 01251ddf4831ca3fc331cb4517ea6797 346 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 30 35 - T 29-03-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS21755 bac5d5b01925fedea892336b86884cc6 80 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 1 77 1.3E-32 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS21755 bac5d5b01925fedea892336b86884cc6 80 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 4 69 1.6E-28 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS21755 bac5d5b01925fedea892336b86884cc6 80 Gene3D G3DSA:1.10.1220.10 5 45 2.9E-10 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS21755 bac5d5b01925fedea892336b86884cc6 80 SUPERFAMILY SSF47598 4 45 1.45E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS07325 5b7360d352dab1cc3f351b28b45020c4 111 Gene3D G3DSA:1.10.10.10 2 103 6.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07325 5b7360d352dab1cc3f351b28b45020c4 111 SUPERFAMILY SSF46785 10 101 4.89E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07325 5b7360d352dab1cc3f351b28b45020c4 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 22 37 2.0E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS07325 5b7360d352dab1cc3f351b28b45020c4 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 2.0E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS07325 5b7360d352dab1cc3f351b28b45020c4 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 2.0E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS07325 5b7360d352dab1cc3f351b28b45020c4 111 SMART SM00418 20 98 2.7E-24 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS07325 5b7360d352dab1cc3f351b28b45020c4 111 Pfam PF01022 Bacterial regulatory protein, arsR family 28 71 1.3E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS25250 ff15a47d83b012bef8e93c782ba3aff8 100 Pfam PF01909 Nucleotidyltransferase domain 9 81 3.3E-6 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS25250 ff15a47d83b012bef8e93c782ba3aff8 100 SUPERFAMILY SSF81301 6 88 1.38E-12 T 29-03-2018 THSYN_RS25250 ff15a47d83b012bef8e93c782ba3aff8 100 Gene3D G3DSA:3.30.460.10 2 96 1.1E-10 T 29-03-2018 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 Pfam PF00384 Molybdopterin oxidoreductase 279 643 2.1E-24 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 7 643 2.5E-180 T 29-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 Gene3D G3DSA:3.40.50.740 437 677 9.5E-24 T 29-03-2018 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 SUPERFAMILY SSF54862 83 217 8.37E-37 T 29-03-2018 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 SUPERFAMILY SSF50692 721 774 4.52E-7 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 34 51 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 152 162 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 91 129 6.3E-17 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 SUPERFAMILY SSF53706 220 668 2.2E-79 T 29-03-2018 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 Gene3D G3DSA:2.40.40.20 706 788 2.2E-7 T 29-03-2018 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 SMART SM00929 90 130 4.2E-20 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 SUPERFAMILY SSF54292 4 81 1.05E-16 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 83 1.5E-15 T 29-03-2018 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 Pfam PF01568 Molydopterin dinucleotide binding domain 724 774 2.8E-5 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 105 117 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 Gene3D G3DSA:3.40.50.740 280 436 1.5E-20 T 29-03-2018 THSYN_RS24610 bff33edd8beb6e30c4ffaf0deb3c2d82 791 Gene3D G3DSA:3.10.20.30 1 167 2.8E-13 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 13 456 49.888 T 29-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 23 427 3.0E-188 T 29-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 Pfam PF03144 Elongation factor Tu domain 2 258 317 8.6E-8 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 Gene3D G3DSA:2.40.30.10 324 428 2.3E-25 T 29-03-2018 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 27 176 9.2E-12 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 Gene3D G3DSA:3.40.50.300 452 624 9.8E-49 T 29-03-2018 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 SUPERFAMILY SSF50447 237 324 8.73E-23 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 SUPERFAMILY SSF52540 14 229 7.33E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 444 623 1.5E-73 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 SUPERFAMILY SSF52540 455 622 4.91E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 455 624 36.372 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 Gene3D G3DSA:3.40.50.300 4 220 6.2E-38 T 29-03-2018 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 77 92 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 SUPERFAMILY SSF50465 325 427 3.36E-31 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 PRINTS PR00315 GTP-binding elongation factor signature 120 131 9.7E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 PRINTS PR00315 GTP-binding elongation factor signature 104 114 9.7E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 PRINTS PR00315 GTP-binding elongation factor signature 23 36 9.7E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 PRINTS PR00315 GTP-binding elongation factor signature 157 166 9.7E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 PRINTS PR00315 GTP-binding elongation factor signature 84 92 9.7E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 Pfam PF01583 Adenylylsulphate kinase 458 608 1.3E-71 T 29-03-2018 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 Pfam PF00009 Elongation factor Tu GTP binding domain 20 220 1.3E-40 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS32130 8a92ae20bfb0a575c6729641466d4432 624 Gene3D G3DSA:2.40.30.10 221 322 2.0E-22 T 29-03-2018 THSYN_RS13625 8aab423b008dd1c4906c044d7ad76279 173 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 39 150 8.0E-15 T 29-03-2018 IPR031982 Type IV minor pilin ComP THSYN_RS13625 8aab423b008dd1c4906c044d7ad76279 173 Pfam PF07963 Prokaryotic N-terminal methylation motif 13 38 2.3E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS13625 8aab423b008dd1c4906c044d7ad76279 173 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 16 36 1.1E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS13625 8aab423b008dd1c4906c044d7ad76279 173 SUPERFAMILY SSF54523 18 159 9.42E-18 T 29-03-2018 THSYN_RS13625 8aab423b008dd1c4906c044d7ad76279 173 Gene3D G3DSA:3.30.700.10 18 172 5.5E-16 T 29-03-2018 THSYN_RS05185 32c02a49b9621bf37408aead7a0ff374 284 Gene3D G3DSA:3.90.1570.10 12 178 2.6E-10 T 29-03-2018 THSYN_RS05185 32c02a49b9621bf37408aead7a0ff374 284 SUPERFAMILY SSF52980 19 173 1.07E-14 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS05185 32c02a49b9621bf37408aead7a0ff374 284 Gene3D G3DSA:1.10.10.60 218 255 1.4E-4 T 29-03-2018 THSYN_RS05185 32c02a49b9621bf37408aead7a0ff374 284 Gene3D G3DSA:1.10.10.60 200 217 0.46 T 29-03-2018 THSYN_RS05185 32c02a49b9621bf37408aead7a0ff374 284 Pfam PF05685 Putative restriction endonuclease 19 158 4.1E-10 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS01020 6d4c0be0fc2ae3987396e650649ffd18 1095 SMART SM00487 624 811 2.8E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS01020 6d4c0be0fc2ae3987396e650649ffd18 1095 Pfam PF00271 Helicase conserved C-terminal domain 925 1034 2.8E-18 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS01020 6d4c0be0fc2ae3987396e650649ffd18 1095 Gene3D G3DSA:3.40.50.10810 599 848 7.2E-51 T 29-03-2018 THSYN_RS01020 6d4c0be0fc2ae3987396e650649ffd18 1095 SUPERFAMILY SSF52540 841 1084 3.29E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS01020 6d4c0be0fc2ae3987396e650649ffd18 1095 SMART SM00490 954 1034 3.1E-22 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS01020 6d4c0be0fc2ae3987396e650649ffd18 1095 Gene3D G3DSA:3.40.50.300 914 1072 2.7E-39 T 29-03-2018 THSYN_RS01020 6d4c0be0fc2ae3987396e650649ffd18 1095 Pfam PF00176 SNF2 family N-terminal domain 646 911 1.2E-61 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THSYN_RS01020 6d4c0be0fc2ae3987396e650649ffd18 1095 Pfam PF04434 SWIM zinc finger 68 95 1.3E-5 T 29-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 THSYN_RS01020 6d4c0be0fc2ae3987396e650649ffd18 1095 SUPERFAMILY SSF52540 593 839 2.94E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS18610 e20fa266e05500d74b13503134e76bd5 406 SMART SM00448 48 162 2.5E-11 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18610 e20fa266e05500d74b13503134e76bd5 406 SUPERFAMILY SSF52172 49 152 3.13E-20 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS18610 e20fa266e05500d74b13503134e76bd5 406 Pfam PF00072 Response regulator receiver domain 50 148 4.8E-13 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18610 e20fa266e05500d74b13503134e76bd5 406 Pfam PF01339 CheB methylesterase 222 397 1.8E-44 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS18610 e20fa266e05500d74b13503134e76bd5 406 Gene3D G3DSA:3.40.50.2300 40 182 8.3E-20 T 29-03-2018 THSYN_RS18610 e20fa266e05500d74b13503134e76bd5 406 Gene3D G3DSA:3.40.50.180 212 406 2.1E-57 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS18610 e20fa266e05500d74b13503134e76bd5 406 SUPERFAMILY SSF52738 219 404 1.57E-47 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS18610 e20fa266e05500d74b13503134e76bd5 406 PIRSF PIRSF000876 46 406 1.8E-78 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS20815 c48c01b4174566dada76cc10b48df785 371 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 15 367 1.4E-101 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 THSYN_RS20815 c48c01b4174566dada76cc10b48df785 371 Gene3D G3DSA:3.90.1150.10 262 371 7.0E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS20815 c48c01b4174566dada76cc10b48df785 371 Gene3D G3DSA:3.40.640.10 53 261 1.5E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS20815 c48c01b4174566dada76cc10b48df785 371 Pfam PF00155 Aminotransferase class I and II 41 361 3.2E-50 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THSYN_RS20815 c48c01b4174566dada76cc10b48df785 371 SUPERFAMILY SSF53383 9 368 3.4E-78 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS20815 c48c01b4174566dada76cc10b48df785 371 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 11 368 59.771 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 THSYN_RS17150 ef478200d47c1cd13ee29ccfae117ae8 382 Gene3D G3DSA:1.10.287.470 130 177 1.5E-6 T 29-03-2018 THSYN_RS17150 ef478200d47c1cd13ee29ccfae117ae8 382 Gene3D G3DSA:2.40.50.100 178 341 0.0062 T 29-03-2018 THSYN_RS17150 ef478200d47c1cd13ee29ccfae117ae8 382 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 76 285 3.5E-18 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS17150 ef478200d47c1cd13ee29ccfae117ae8 382 SUPERFAMILY SSF111369 63 290 1.96E-19 T 29-03-2018 THSYN_RS17150 ef478200d47c1cd13ee29ccfae117ae8 382 Gene3D G3DSA:2.40.50.100 27 129 1.1E-11 T 29-03-2018 THSYN_RS17150 ef478200d47c1cd13ee29ccfae117ae8 382 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 48 365 2.1E-61 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS17520 49dd6b359433a05fac131c96cfdaef30 296 PRINTS PR00478 Phosphoribulokinase family signature 188 211 1.0E-33 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS17520 49dd6b359433a05fac131c96cfdaef30 296 PRINTS PR00478 Phosphoribulokinase family signature 132 150 1.0E-33 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS17520 49dd6b359433a05fac131c96cfdaef30 296 PRINTS PR00478 Phosphoribulokinase family signature 170 187 1.0E-33 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS17520 49dd6b359433a05fac131c96cfdaef30 296 PRINTS PR00478 Phosphoribulokinase family signature 12 29 1.0E-33 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS17520 49dd6b359433a05fac131c96cfdaef30 296 ProSitePatterns PS00567 Phosphoribulokinase signature. 170 183 - T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS17520 49dd6b359433a05fac131c96cfdaef30 296 SUPERFAMILY SSF52540 3 293 4.02E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17520 49dd6b359433a05fac131c96cfdaef30 296 Gene3D G3DSA:3.40.50.300 1 296 2.0E-46 T 29-03-2018 THSYN_RS17520 49dd6b359433a05fac131c96cfdaef30 296 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 220 1.2E-69 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 THSYN_RS09775 b9db32c4dc50212cc318300a53b85fdb 604 Gene3D G3DSA:3.30.1490.150 535 590 6.7E-17 T 29-03-2018 THSYN_RS09775 b9db32c4dc50212cc318300a53b85fdb 604 Pfam PF01871 AMMECR1 446 593 1.8E-45 T 29-03-2018 IPR002733 AMMECR1 domain THSYN_RS09775 b9db32c4dc50212cc318300a53b85fdb 604 SUPERFAMILY SSF143447 448 599 5.76E-50 T 29-03-2018 IPR002733 AMMECR1 domain THSYN_RS09775 b9db32c4dc50212cc318300a53b85fdb 604 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 96 371 1.9E-63 T 29-03-2018 THSYN_RS09775 b9db32c4dc50212cc318300a53b85fdb 604 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 444 593 5.2E-47 T 29-03-2018 IPR027623 AmmeMemoRadiSam system protein A THSYN_RS09775 b9db32c4dc50212cc318300a53b85fdb 604 Gene3D G3DSA:3.40.830.10 98 378 3.5E-38 T 29-03-2018 THSYN_RS09775 b9db32c4dc50212cc318300a53b85fdb 604 Pfam PF01875 Memo-like protein 98 370 8.0E-60 T 29-03-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 THSYN_RS09775 b9db32c4dc50212cc318300a53b85fdb 604 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 445 581 5.5E-34 T 29-03-2018 IPR023473 AMMECR1 THSYN_RS09775 b9db32c4dc50212cc318300a53b85fdb 604 Gene3D G3DSA:3.30.700.20 411 534 1.1E-31 T 29-03-2018 IPR027485 AMMECR1, N-terminal THSYN_RS09775 b9db32c4dc50212cc318300a53b85fdb 604 Hamap MF_00055 MEMO1 family protein . 94 373 48.086 T 29-03-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 THSYN_RS32180 41f39a781cdfb2d9a6b2b6ea9dbd1232 383 SUPERFAMILY SSF111342 17 303 3.27E-74 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 THSYN_RS32180 41f39a781cdfb2d9a6b2b6ea9dbd1232 383 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 30 349 2.4E-58 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 THSYN_RS32180 41f39a781cdfb2d9a6b2b6ea9dbd1232 383 PIRSF PIRSF026782 18 382 1.7E-96 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 THSYN_RS32180 41f39a781cdfb2d9a6b2b6ea9dbd1232 383 Gene3D G3DSA:3.30.2110.10 24 199 1.2E-55 T 29-03-2018 THSYN_RS32180 41f39a781cdfb2d9a6b2b6ea9dbd1232 383 Pfam PF01888 CbiD 23 285 6.5E-81 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 THSYN_RS32180 41f39a781cdfb2d9a6b2b6ea9dbd1232 383 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 22 377 26.168 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 THSYN_RS29295 a2015a5b1471f62db9807fdce72a00cf 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 1.0E-12 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS29295 a2015a5b1471f62db9807fdce72a00cf 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 29-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS29295 a2015a5b1471f62db9807fdce72a00cf 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 43 2.1E-23 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS29295 a2015a5b1471f62db9807fdce72a00cf 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.749 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS29295 a2015a5b1471f62db9807fdce72a00cf 44 Pfam PF00468 Ribosomal protein L34 1 43 3.0E-22 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS15840 4c8ef12d0c53f4802c46fd49138a5d74 237 SUPERFAMILY SSF51735 6 220 8.0E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS15840 4c8ef12d0c53f4802c46fd49138a5d74 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS15840 4c8ef12d0c53f4802c46fd49138a5d74 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS15840 4c8ef12d0c53f4802c46fd49138a5d74 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS15840 4c8ef12d0c53f4802c46fd49138a5d74 237 Gene3D G3DSA:3.40.50.720 3 200 3.8E-61 T 29-03-2018 THSYN_RS15840 4c8ef12d0c53f4802c46fd49138a5d74 237 Pfam PF00106 short chain dehydrogenase 6 198 4.5E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS15840 4c8ef12d0c53f4802c46fd49138a5d74 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS15840 4c8ef12d0c53f4802c46fd49138a5d74 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS15840 4c8ef12d0c53f4802c46fd49138a5d74 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 3.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS15840 4c8ef12d0c53f4802c46fd49138a5d74 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS15840 4c8ef12d0c53f4802c46fd49138a5d74 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 3.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS04735 f66f0abf35e6225bd17a8d60398a97c3 978 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 484 490 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS04735 f66f0abf35e6225bd17a8d60398a97c3 978 SUPERFAMILY SSF53335 368 591 7.63E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS04735 f66f0abf35e6225bd17a8d60398a97c3 978 SUPERFAMILY SSF53335 168 320 7.63E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS04735 f66f0abf35e6225bd17a8d60398a97c3 978 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 481 493 5.9E-6 T 29-03-2018 THSYN_RS04735 f66f0abf35e6225bd17a8d60398a97c3 978 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 372 386 5.9E-6 T 29-03-2018 THSYN_RS04735 f66f0abf35e6225bd17a8d60398a97c3 978 Gene3D G3DSA:3.40.50.150 299 668 2.4E-19 T 29-03-2018 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 Gene3D G3DSA:2.40.10.10 211 312 9.3E-38 T 29-03-2018 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 Pfam PF13180 PDZ domain 312 403 9.7E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 Gene3D G3DSA:2.40.10.10 69 210 1.1E-37 T 29-03-2018 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 SUPERFAMILY SSF50494 71 95 8.04E-63 T 29-03-2018 IPR009003 Peptidase S1, PA clan THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 SUPERFAMILY SSF50494 125 309 8.04E-63 T 29-03-2018 IPR009003 Peptidase S1, PA clan THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 Gene3D G3DSA:2.30.42.10 421 522 5.0E-19 T 29-03-2018 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 Gene3D G3DSA:2.30.42.10 313 416 9.2E-26 T 29-03-2018 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 SUPERFAMILY SSF50156 270 394 3.94E-23 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 425 507 1.4E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 72 517 1.4E-142 T 29-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 Pfam PF13365 Trypsin-like peptidase domain 139 273 1.6E-34 T 29-03-2018 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 SUPERFAMILY SSF50156 425 519 2.23E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 PRINTS PR00834 HtrA/DegQ protease family signature 352 364 4.7E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 PRINTS PR00834 HtrA/DegQ protease family signature 266 283 4.7E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 PRINTS PR00834 HtrA/DegQ protease family signature 210 234 4.7E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 PRINTS PR00834 HtrA/DegQ protease family signature 148 160 4.7E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 PRINTS PR00834 HtrA/DegQ protease family signature 169 189 4.7E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 PRINTS PR00834 HtrA/DegQ protease family signature 244 261 4.7E-48 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 SMART SM00228 312 394 3.1E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08205 8ca17092450e207508229bb63ee2b4de 522 SMART SM00228 426 511 2.1E-9 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS13250 772eb9d904d6796679a9c5cb9135ffe8 727 SUPERFAMILY SSF75138 209 334 5.49E-17 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like THSYN_RS13250 772eb9d904d6796679a9c5cb9135ffe8 727 Pfam PF13500 AAA domain 2 204 7.2E-23 T 29-03-2018 THSYN_RS13250 772eb9d904d6796679a9c5cb9135ffe8 727 Gene3D G3DSA:3.40.50.300 1 208 3.9E-25 T 29-03-2018 THSYN_RS13250 772eb9d904d6796679a9c5cb9135ffe8 727 Gene3D G3DSA:3.40.50.2000 384 484 0.078 T 29-03-2018 THSYN_RS13250 772eb9d904d6796679a9c5cb9135ffe8 727 Pfam PF01515 Phosphate acetyl/butaryl transferase 372 689 4.2E-127 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS13250 772eb9d904d6796679a9c5cb9135ffe8 727 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 388 689 1.8E-125 T 29-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS13250 772eb9d904d6796679a9c5cb9135ffe8 727 SUPERFAMILY SSF53659 372 692 9.46E-97 T 29-03-2018 THSYN_RS13250 772eb9d904d6796679a9c5cb9135ffe8 727 Gene3D G3DSA:3.40.1390.20 209 349 1.9E-26 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like THSYN_RS13250 772eb9d904d6796679a9c5cb9135ffe8 727 Pfam PF07085 DRTGG domain 212 326 3.9E-22 T 29-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS13250 772eb9d904d6796679a9c5cb9135ffe8 727 PIRSF PIRSF006107 1 697 3.5E-179 T 29-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS13250 772eb9d904d6796679a9c5cb9135ffe8 727 Gene3D G3DSA:3.40.50.10750 512 665 1.4E-63 T 29-03-2018 THSYN_RS13250 772eb9d904d6796679a9c5cb9135ffe8 727 SUPERFAMILY SSF52540 1 212 7.97E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22325 b181f370416f654d460c670ba0b1fa88 194 Gene3D G3DSA:3.90.1570.10 4 185 7.3E-40 T 29-03-2018 THSYN_RS22325 b181f370416f654d460c670ba0b1fa88 194 Pfam PF05685 Putative restriction endonuclease 13 170 4.8E-31 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS22325 b181f370416f654d460c670ba0b1fa88 194 SUPERFAMILY SSF52980 6 179 9.65E-23 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS10065 4f50e170e1788f08bf77a5eb48ba29c4 275 Pfam PF01435 Peptidase family M48 67 150 3.6E-9 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THSYN_RS10065 4f50e170e1788f08bf77a5eb48ba29c4 275 Gene3D G3DSA:3.30.2010.10 60 152 2.4E-10 T 29-03-2018 THSYN_RS01375 dd0105933206dac9323158e64c6876e3 98 SUPERFAMILY SSF159127 1 81 1.83E-19 T 29-03-2018 THSYN_RS01375 dd0105933206dac9323158e64c6876e3 98 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 72 2.6E-22 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS01375 dd0105933206dac9323158e64c6876e3 98 Pfam PF01455 HupF/HypC family 1 65 2.4E-17 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS01375 dd0105933206dac9323158e64c6876e3 98 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 56 68 6.7E-10 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS01375 dd0105933206dac9323158e64c6876e3 98 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 6.7E-10 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS01375 dd0105933206dac9323158e64c6876e3 98 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 6.7E-10 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS01375 dd0105933206dac9323158e64c6876e3 98 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 6.7E-10 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS01375 dd0105933206dac9323158e64c6876e3 98 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 29-03-2018 IPR019812 Hydrogenase assembly chaperone, conserved site THSYN_RS30135 7365551cd491fe82552322657e032321 263 SUPERFAMILY SSF69572 14 158 1.57E-10 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THSYN_RS30135 7365551cd491fe82552322657e032321 263 TIGRFAM TIGR03736 PRTRC_ThiF: PRTRC system ThiF family protein 5 248 1.2E-69 T 29-03-2018 IPR022500 ParB-related, ThiF-related cassette, ThiF THSYN_RS30135 7365551cd491fe82552322657e032321 263 Pfam PF00899 ThiF family 14 125 9.4E-10 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THSYN_RS30135 7365551cd491fe82552322657e032321 263 Gene3D G3DSA:3.40.50.720 13 253 1.1E-15 T 29-03-2018 THSYN_RS00295 ff1813ae8719cecbd1f509cb8fbf6f48 540 SUPERFAMILY SSF160964 21 286 1.96E-61 T 29-03-2018 THSYN_RS00295 ff1813ae8719cecbd1f509cb8fbf6f48 540 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 323 527 5.4E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS00295 ff1813ae8719cecbd1f509cb8fbf6f48 540 Gene3D G3DSA:2.40.430.10 127 216 1.3E-20 T 29-03-2018 THSYN_RS00295 ff1813ae8719cecbd1f509cb8fbf6f48 540 Gene3D G3DSA:3.10.650.10 217 295 1.3E-22 T 29-03-2018 THSYN_RS00295 ff1813ae8719cecbd1f509cb8fbf6f48 540 Gene3D G3DSA:1.10.3720.10 297 537 2.5E-39 T 29-03-2018 THSYN_RS00295 ff1813ae8719cecbd1f509cb8fbf6f48 540 SUPERFAMILY SSF161098 287 529 8.5E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS00295 ff1813ae8719cecbd1f509cb8fbf6f48 540 Pfam PF14785 Maltose transport system permease protein MalF P2 domain 107 286 3.5E-39 T 29-03-2018 IPR029345 Maltose transport system permease protein MalF, P2 domain THSYN_RS00295 ff1813ae8719cecbd1f509cb8fbf6f48 540 Gene3D G3DSA:1.20.58.370 13 102 5.3E-22 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain THSYN_RS19335 f788ef1c628ead201e55025888a7dc7d 2857 Gene3D G3DSA:1.50.10.10 2369 2744 3.9E-77 T 29-03-2018 THSYN_RS19335 f788ef1c628ead201e55025888a7dc7d 2857 Pfam PF10091 Putative glucoamylase 1315 1524 8.3E-13 T 29-03-2018 IPR019282 Domain of unknown function DUF2329 THSYN_RS19335 f788ef1c628ead201e55025888a7dc7d 2857 SMART SM01068 2060 2125 1.1E-34 T 29-03-2018 IPR009342 Putative carbohydrate binding domain THSYN_RS19335 f788ef1c628ead201e55025888a7dc7d 2857 SMART SM01068 1554 1612 3.2E-19 T 29-03-2018 IPR009342 Putative carbohydrate binding domain THSYN_RS19335 f788ef1c628ead201e55025888a7dc7d 2857 SUPERFAMILY SSF48208 2341 2855 1.21E-96 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 THSYN_RS19335 f788ef1c628ead201e55025888a7dc7d 2857 SUPERFAMILY SSF74650 2060 2326 1.66E-91 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 THSYN_RS19335 f788ef1c628ead201e55025888a7dc7d 2857 Gene3D G3DSA:2.60.420.10 2773 2857 8.2E-23 T 29-03-2018 THSYN_RS19335 f788ef1c628ead201e55025888a7dc7d 2857 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 2355 2780 1.4E-115 T 29-03-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain THSYN_RS19335 f788ef1c628ead201e55025888a7dc7d 2857 SUPERFAMILY SSF74650 1566 1824 1.69E-79 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 THSYN_RS19335 f788ef1c628ead201e55025888a7dc7d 2857 Gene3D G3DSA:2.70.98.40 1559 1836 2.8E-83 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 THSYN_RS19335 f788ef1c628ead201e55025888a7dc7d 2857 Gene3D G3DSA:2.70.98.40 2061 2338 4.1E-98 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 THSYN_RS19335 f788ef1c628ead201e55025888a7dc7d 2857 Pfam PF06165 Glycosyltransferase family 36 1575 1821 5.5E-77 T 29-03-2018 IPR010383 Glycosyl hydrolase 94 THSYN_RS19335 f788ef1c628ead201e55025888a7dc7d 2857 Pfam PF06165 Glycosyltransferase family 36 2083 2324 4.4E-83 T 29-03-2018 IPR010383 Glycosyl hydrolase 94 THSYN_RS19760 32e334b5d2f7ef6b781fc939eca2a02b 467 Pfam PF05193 Peptidase M16 inactive domain 197 379 5.3E-28 T 29-03-2018 IPR007863 Peptidase M16, C-terminal THSYN_RS19760 32e334b5d2f7ef6b781fc939eca2a02b 467 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 63 86 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 THSYN_RS19760 32e334b5d2f7ef6b781fc939eca2a02b 467 SUPERFAMILY SSF63411 258 446 5.42E-37 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THSYN_RS19760 32e334b5d2f7ef6b781fc939eca2a02b 467 Pfam PF00675 Insulinase (Peptidase family M16) 43 188 4.8E-25 T 29-03-2018 IPR011765 Peptidase M16, N-terminal THSYN_RS19760 32e334b5d2f7ef6b781fc939eca2a02b 467 SUPERFAMILY SSF63411 28 236 6.83E-62 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THSYN_RS19760 32e334b5d2f7ef6b781fc939eca2a02b 467 Gene3D G3DSA:3.30.830.10 256 457 2.0E-38 T 29-03-2018 THSYN_RS19760 32e334b5d2f7ef6b781fc939eca2a02b 467 Gene3D G3DSA:3.30.830.10 15 252 2.8E-64 T 29-03-2018 THSYN_RS19600 df472c7986d4897bb9ab2612fb2a6e9c 375 Gene3D G3DSA:1.10.3470.10 18 343 5.7E-45 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like THSYN_RS19600 df472c7986d4897bb9ab2612fb2a6e9c 375 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 338 2.8E-51 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THSYN_RS20825 70062d397f8172b00e484985402cef81 389 SUPERFAMILY SSF51735 83 274 1.68E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS20825 70062d397f8172b00e484985402cef81 389 Gene3D G3DSA:3.30.70.260 308 387 9.3E-11 T 29-03-2018 THSYN_RS20825 70062d397f8172b00e484985402cef81 389 SUPERFAMILY SSF55021 312 387 3.08E-12 T 29-03-2018 THSYN_RS20825 70062d397f8172b00e484985402cef81 389 Gene3D G3DSA:3.40.50.10730 116 164 1.3E-4 T 29-03-2018 THSYN_RS20825 70062d397f8172b00e484985402cef81 389 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 102 274 2.3E-40 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 THSYN_RS20825 70062d397f8172b00e484985402cef81 389 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 19 306 2.4E-19 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 THSYN_RS20825 70062d397f8172b00e484985402cef81 389 Gene3D G3DSA:3.40.50.720 165 306 3.5E-35 T 29-03-2018 THSYN_RS20825 70062d397f8172b00e484985402cef81 389 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 191 213 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site THSYN_RS20825 70062d397f8172b00e484985402cef81 389 SUPERFAMILY SSF52283 4 106 2.84E-20 T 29-03-2018 THSYN_RS20825 70062d397f8172b00e484985402cef81 389 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 140 167 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 THSYN_RS20825 70062d397f8172b00e484985402cef81 389 Gene3D G3DSA:3.40.50.720 2 113 1.1E-21 T 29-03-2018 THSYN_RS13655 7ab14ae1186a8d36af2e3f10746c3d28 692 SMART SM00052 444 689 3.9E-20 T 29-03-2018 IPR001633 EAL domain THSYN_RS13655 7ab14ae1186a8d36af2e3f10746c3d28 692 SUPERFAMILY SSF55073 280 414 2.67E-11 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS13655 7ab14ae1186a8d36af2e3f10746c3d28 692 SUPERFAMILY SSF52172 12 147 2.82E-5 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS13655 7ab14ae1186a8d36af2e3f10746c3d28 692 Gene3D G3DSA:3.20.20.450 434 692 6.3E-52 T 29-03-2018 IPR001633 EAL domain THSYN_RS13655 7ab14ae1186a8d36af2e3f10746c3d28 692 SUPERFAMILY SSF55785 133 253 2.27E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS13655 7ab14ae1186a8d36af2e3f10746c3d28 692 Pfam PF00563 EAL domain 454 684 6.7E-43 T 29-03-2018 IPR001633 EAL domain THSYN_RS13655 7ab14ae1186a8d36af2e3f10746c3d28 692 Gene3D G3DSA:3.30.450.20 113 260 3.3E-10 T 29-03-2018 THSYN_RS13655 7ab14ae1186a8d36af2e3f10746c3d28 692 SMART SM00267 275 428 8.4E-4 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS13655 7ab14ae1186a8d36af2e3f10746c3d28 692 Gene3D G3DSA:3.30.70.270 272 423 5.9E-15 T 29-03-2018 THSYN_RS13655 7ab14ae1186a8d36af2e3f10746c3d28 692 Pfam PF00990 Diguanylate cyclase, GGDEF domain 282 413 1.0E-5 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS13655 7ab14ae1186a8d36af2e3f10746c3d28 692 SUPERFAMILY SSF141868 452 689 3.53E-44 T 29-03-2018 IPR001633 EAL domain THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 Gene3D G3DSA:3.30.450.20 122 242 1.8E-9 T 29-03-2018 THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 409 426 4.1E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 426 446 4.1E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 Gene3D G3DSA:1.10.10.60 385 450 2.8E-14 T 29-03-2018 THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 SUPERFAMILY SSF55785 258 366 4.0E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 TIGRFAM TIGR02040 PpsR-CrtJ: transcriptional regulator PpsR 8 445 2.2E-144 T 29-03-2018 IPR011785 Transcription regulator PpsR THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 SMART SM00091 134 204 0.09 T 29-03-2018 IPR000014 PAS domain THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 SMART SM00091 257 326 0.042 T 29-03-2018 IPR000014 PAS domain THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 SUPERFAMILY SSF55785 126 231 2.42E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 Pfam PF02954 Bacterial regulatory protein, Fis family 403 443 7.3E-14 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 SUPERFAMILY SSF46689 378 446 1.52E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 Pfam PF13188 PAS domain 135 193 8.9E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 Gene3D G3DSA:3.30.450.20 6 121 1.8E-5 T 29-03-2018 THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 Pfam PF13426 PAS domain 267 367 3.3E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS31820 e01f4887a6baa0b2a70938e79397f26b 459 Gene3D G3DSA:3.30.450.20 256 368 2.3E-9 T 29-03-2018 THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 SUPERFAMILY SSF52172 1048 1166 1.41E-29 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 SMART SM00448 1050 1161 2.2E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 SMART SM00387 907 1030 4.5E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 SUPERFAMILY SSF55781 461 603 4.14E-11 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 Gene3D G3DSA:3.30.565.10 867 1030 2.8E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 908 1028 1.1E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 Gene3D G3DSA:3.30.450.40 426 624 8.0E-11 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 Gene3D G3DSA:1.10.287.130 791 863 0.0014 T 29-03-2018 THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 PRINTS PR00344 Bacterial sensor protein C-terminal signature 959 973 4.6E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 PRINTS PR00344 Bacterial sensor protein C-terminal signature 977 987 4.6E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 PRINTS PR00344 Bacterial sensor protein C-terminal signature 990 1008 4.6E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1014 1027 4.6E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 Gene3D G3DSA:3.40.50.2300 1046 1168 4.1E-29 T 29-03-2018 THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 Pfam PF00072 Response regulator receiver domain 1052 1158 1.1E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00580 16167b8592af5f695009a4701db00307 1169 SUPERFAMILY SSF55874 858 1029 1.11E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS33005 33cfed6853c6a2959b79da6605b82f2f 180 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 31 176 8.6E-36 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase THSYN_RS33005 33cfed6853c6a2959b79da6605b82f2f 180 Gene3D G3DSA:3.30.530.20 12 180 1.2E-34 T 29-03-2018 IPR023393 START-like domain THSYN_RS33005 33cfed6853c6a2959b79da6605b82f2f 180 SUPERFAMILY SSF55961 31 176 2.95E-30 T 29-03-2018 THSYN_RS16065 9cc89fa44c9debad8d5bf452a96e53ee 347 SUPERFAMILY SSF140931 85 280 3.14E-32 T 29-03-2018 IPR003812 Fido domain THSYN_RS16065 9cc89fa44c9debad8d5bf452a96e53ee 347 Pfam PF02661 Fic/DOC family 108 211 8.4E-17 T 29-03-2018 IPR003812 Fido domain THSYN_RS16065 9cc89fa44c9debad8d5bf452a96e53ee 347 Gene3D G3DSA:1.10.3290.10 19 291 1.2E-47 T 29-03-2018 IPR003812 Fido domain THSYN_RS04745 4094ba5d9c1d3e72c93ae6469973e8f0 96 SUPERFAMILY SSF47413 38 82 2.82E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS04745 4094ba5d9c1d3e72c93ae6469973e8f0 96 Pfam PF13560 Helix-turn-helix domain 41 86 3.4E-6 T 29-03-2018 THSYN_RS04745 4094ba5d9c1d3e72c93ae6469973e8f0 96 Gene3D G3DSA:1.10.260.40 12 95 5.4E-12 T 29-03-2018 THSYN_RS01160 91e917edb3ee11b7bd00fbdb4d8d0604 225 SUPERFAMILY SSF159594 42 213 5.75E-27 T 29-03-2018 THSYN_RS01160 91e917edb3ee11b7bd00fbdb4d8d0604 225 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 45 206 2.9E-30 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component THSYN_RS01160 91e917edb3ee11b7bd00fbdb4d8d0604 225 Gene3D G3DSA:3.40.50.10610 31 221 9.8E-38 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component THSYN_RS02315 7df9bd13ad204c4b07c17ace2e63b0d3 212 Gene3D G3DSA:3.40.50.300 4 206 1.2E-25 T 29-03-2018 THSYN_RS02315 7df9bd13ad204c4b07c17ace2e63b0d3 212 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 8 200 2.4E-64 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 THSYN_RS02315 7df9bd13ad204c4b07c17ace2e63b0d3 212 SUPERFAMILY SSF52540 16 202 1.16E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02315 7df9bd13ad204c4b07c17ace2e63b0d3 212 Pfam PF01926 50S ribosome-binding GTPase 27 145 3.1E-18 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS02315 7df9bd13ad204c4b07c17ace2e63b0d3 212 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 13 204 25.581 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 THSYN_RS21150 ebc6b85e594d8fbb405ecad42a5391a3 322 SUPERFAMILY SSF53335 26 320 1.3E-67 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS21150 ebc6b85e594d8fbb405ecad42a5391a3 322 Pfam PF01555 DNA methylase 52 316 6.1E-40 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THSYN_RS21150 ebc6b85e594d8fbb405ecad42a5391a3 322 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 56 61 - T 29-03-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS21150 ebc6b85e594d8fbb405ecad42a5391a3 322 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 84 104 1.5E-24 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS21150 ebc6b85e594d8fbb405ecad42a5391a3 322 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 277 295 1.5E-24 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS21150 ebc6b85e594d8fbb405ecad42a5391a3 322 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 258 275 1.5E-24 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS21150 ebc6b85e594d8fbb405ecad42a5391a3 322 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 300 320 1.5E-24 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS21150 ebc6b85e594d8fbb405ecad42a5391a3 322 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 51 65 1.5E-24 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS21150 ebc6b85e594d8fbb405ecad42a5391a3 322 Gene3D G3DSA:3.40.50.150 21 322 9.0E-49 T 29-03-2018 THSYN_RS16970 c9ed8bbeeba3acbabe90c84cb34de6cd 330 SUPERFAMILY SSF53067 1 326 5.7E-51 T 29-03-2018 THSYN_RS16970 c9ed8bbeeba3acbabe90c84cb34de6cd 330 Gene3D G3DSA:3.30.420.40 2 117 2.1E-18 T 29-03-2018 THSYN_RS16970 c9ed8bbeeba3acbabe90c84cb34de6cd 330 Hamap MF_00524 Glucokinase [glk]. 2 330 31.992 T 29-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 THSYN_RS16970 c9ed8bbeeba3acbabe90c84cb34de6cd 330 Gene3D G3DSA:3.40.367.20 118 313 1.2E-28 T 29-03-2018 THSYN_RS16970 c9ed8bbeeba3acbabe90c84cb34de6cd 330 TIGRFAM TIGR00749 glk: glucokinase 4 324 1.3E-76 T 29-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 THSYN_RS16970 c9ed8bbeeba3acbabe90c84cb34de6cd 330 Pfam PF02685 Glucokinase 4 327 8.4E-98 T 29-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Gene3D G3DSA:3.10.20.30 16 130 7.0E-14 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Gene3D G3DSA:3.30.70.20 181 216 5.3E-8 T 29-03-2018 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Pfam PF00384 Molybdopterin oxidoreductase 298 729 1.6E-70 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 246 851 1.2E-247 T 29-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 SUPERFAMILY SSF54292 20 92 4.11E-18 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 214 225 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 242 293 2.9E-15 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 SUPERFAMILY SSF54862 93 236 7.95E-37 T 29-03-2018 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 SUPERFAMILY SSF50692 769 849 2.49E-9 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Gene3D G3DSA:2.20.25.90 241 299 1.8E-16 T 29-03-2018 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 18 94 3.3E-22 T 29-03-2018 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Gene3D G3DSA:3.30.70.20 152 180 0.0062 T 29-03-2018 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 SMART SM00926 241 295 2.2E-14 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Gene3D G3DSA:3.30.70.20 217 240 2.9E-4 T 29-03-2018 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 101 140 3.7E-17 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 PIRSF PIRSF036643 15 857 0.0 T 29-03-2018 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 SUPERFAMILY SSF53706 242 779 8.25E-190 T 29-03-2018 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Gene3D G3DSA:2.40.40.20 794 852 1.5E-6 T 29-03-2018 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Pfam PF00037 4Fe-4S binding domain 210 227 1.1E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Gene3D G3DSA:3.40.50.740 300 402 2.7E-24 T 29-03-2018 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 SMART SM00929 101 141 6.9E-19 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Gene3D G3DSA:3.40.228.10 403 493 3.8E-18 T 29-03-2018 THSYN_RS33185 9a1e4236dba744121baa7f48b4d15ef2 876 Gene3D G3DSA:3.40.50.740 500 781 2.7E-77 T 29-03-2018 THSYN_RS15800 ed93438d390402637f1be92211882750 305 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS15800 ed93438d390402637f1be92211882750 305 SMART SM00382 30 209 1.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS15800 ed93438d390402637f1be92211882750 305 SUPERFAMILY SSF52540 4 212 1.05E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15800 ed93438d390402637f1be92211882750 305 Gene3D G3DSA:3.40.50.300 2 249 3.8E-56 T 29-03-2018 THSYN_RS15800 ed93438d390402637f1be92211882750 305 Pfam PF00005 ABC transporter 21 163 7.7E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS08520 2419862623026b50cac8f19807ba4167 60 SUPERFAMILY SSF88723 4 57 1.74E-12 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS08520 2419862623026b50cac8f19807ba4167 60 Gene3D G3DSA:3.40.50.1010 2 19 0.015 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS08520 2419862623026b50cac8f19807ba4167 60 Gene3D G3DSA:3.40.50.1010 20 59 1.6E-9 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS19435 03ff16b510d19159979e990fafa24c20 96 PIRSF PIRSF032582 1 96 5.0E-35 T 29-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THSYN_RS19435 03ff16b510d19159979e990fafa24c20 96 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 75 3.3E-16 T 29-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THSYN_RS19435 03ff16b510d19159979e990fafa24c20 96 Pfam PF09827 CRISPR associated protein Cas2 1 74 2.1E-21 T 29-03-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 THSYN_RS19435 03ff16b510d19159979e990fafa24c20 96 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 15.896 T 29-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THSYN_RS19435 03ff16b510d19159979e990fafa24c20 96 SUPERFAMILY SSF143430 1 86 4.97E-22 T 29-03-2018 THSYN_RS19435 03ff16b510d19159979e990fafa24c20 96 Gene3D G3DSA:3.30.70.240 1 71 4.4E-25 T 29-03-2018 THSYN_RS13965 a1b085a7f37f3fc2c617682e70a89338 262 Gene3D G3DSA:2.50.20.10 10 245 7.1E-11 T 29-03-2018 THSYN_RS10785 6f4b90e7fdb3a0cbbcf629ea56d2f4e7 496 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 367 445 5.1E-12 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain THSYN_RS10785 6f4b90e7fdb3a0cbbcf629ea56d2f4e7 496 Pfam PF13353 4Fe-4S single cluster domain 117 194 4.2E-6 T 29-03-2018 THSYN_RS10785 6f4b90e7fdb3a0cbbcf629ea56d2f4e7 496 SUPERFAMILY SSF102114 114 439 4.84E-45 T 29-03-2018 THSYN_RS10785 6f4b90e7fdb3a0cbbcf629ea56d2f4e7 496 Gene3D G3DSA:3.20.20.70 111 431 1.3E-31 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS10785 6f4b90e7fdb3a0cbbcf629ea56d2f4e7 496 Pfam PF04055 Radical SAM superfamily 120 280 5.1E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS10100 f5d07ca9e160a7a08b9e123a66d0cf88 513 Gene3D G3DSA:1.25.40.80 135 322 6.6E-48 T 29-03-2018 THSYN_RS10100 f5d07ca9e160a7a08b9e123a66d0cf88 513 SUPERFAMILY SSF48173 233 498 1.15E-55 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 THSYN_RS10100 f5d07ca9e160a7a08b9e123a66d0cf88 513 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 9 232 4.8E-71 T 29-03-2018 IPR007357 Deoxyribodipyrimidine photolyase-related protein THSYN_RS10100 f5d07ca9e160a7a08b9e123a66d0cf88 513 Gene3D G3DSA:1.10.579.10 323 501 4.8E-29 T 29-03-2018 THSYN_RS01255 7523ef39f6dcf34f4bbda58c872d4bd8 362 Pfam PF13469 Sulfotransferase family 75 268 2.5E-11 T 29-03-2018 THSYN_RS01255 7523ef39f6dcf34f4bbda58c872d4bd8 362 SUPERFAMILY SSF52540 150 351 2.39E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS01255 7523ef39f6dcf34f4bbda58c872d4bd8 362 SUPERFAMILY SSF52540 72 114 2.39E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS01255 7523ef39f6dcf34f4bbda58c872d4bd8 362 Gene3D G3DSA:3.40.50.300 72 350 7.7E-20 T 29-03-2018 THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 333 4.3E-137 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 Pfam PF01018 GTP1/OBG 4 156 1.3E-55 T 29-03-2018 IPR006169 GTP1/OBG domain THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 Gene3D G3DSA:2.70.210.12 2 156 5.4E-54 T 29-03-2018 IPR006169 GTP1/OBG domain THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 Hamap MF_01454 GTPase Obg [obg]. 2 334 46.659 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 PIRSF PIRSF002401 1 354 1.2E-127 T 29-03-2018 IPR035101 GTP-binding protein, Obg-type THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 SUPERFAMILY SSF52540 152 339 7.92E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 Gene3D G3DSA:3.40.50.300 159 344 7.2E-32 T 29-03-2018 THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 Pfam PF01926 50S ribosome-binding GTPase 161 285 6.6E-23 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 3.2E-33 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.2E-33 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.2E-33 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 3.2E-33 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS24480 400a66d064861aaf2aec837a41896a11 358 SUPERFAMILY SSF82051 2 157 2.62E-54 T 29-03-2018 IPR006169 GTP1/OBG domain THSYN_RS02105 d365247b58224e24a871c68effea8de7 270 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 17 268 9.7E-84 T 29-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria THSYN_RS02105 d365247b58224e24a871c68effea8de7 270 Pfam PF02405 Permease MlaE 55 266 1.1E-73 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SUPERFAMILY SSF81901 243 388 1.92E-34 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Gene3D G3DSA:2.60.40.1180 753 807 1.4E-18 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Gene3D G3DSA:2.60.40.1180 247 320 1.5E-19 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Gene3D G3DSA:2.60.40.1180 180 246 6.0E-14 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Gene3D G3DSA:2.60.40.1180 392 465 9.9E-20 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Gene3D G3DSA:2.60.40.1180 956 987 4.7E-11 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Gene3D G3DSA:2.60.40.1180 701 752 5.8E-13 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Gene3D G3DSA:2.60.40.1180 466 544 1.5E-19 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Gene3D G3DSA:2.60.40.1180 321 390 1.6E-17 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Gene3D G3DSA:2.60.40.1180 906 955 1.9E-22 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Gene3D G3DSA:2.60.40.1180 581 625 4.0E-21 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Gene3D G3DSA:2.60.40.1180 626 689 3.5E-23 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Gene3D G3DSA:2.60.40.1180 808 874 6.8E-18 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 942 977 4.9E-12 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 581 616 1.4E-8 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 472 507 3.9E-8 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 906 941 3.3E-12 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 254 289 5.2E-5 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 508 543 11.0 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 290 325 1.1E-9 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 326 361 7.9E-9 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 653 690 11.0 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 436 471 8.0E-11 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 723 758 5.8E-11 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 691 722 250.0 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 759 795 2.8E-7 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 796 831 4.8E-8 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 870 905 0.039 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 400 435 7.1E-5 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 199 234 1.5E-10 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 832 869 110.0 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 546 580 0.54 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SMART SM00671 617 652 1.9E-9 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 877 905 0.024 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 404 435 1.7E-5 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 618 652 1.9E-9 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 326 361 8.5E-7 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 256 289 0.0018 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 581 616 2.6E-8 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 473 507 4.2E-6 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 199 234 6.7E-9 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 510 537 1.3 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 656 680 0.0051 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 906 941 6.7E-11 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 759 795 5.8E-7 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 942 977 3.0E-9 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 290 325 5.4E-8 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 362 387 0.36 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 797 830 2.4E-6 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 436 471 5.5E-11 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 710 722 0.51 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 723 758 1.1E-8 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 555 580 4.0E-4 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 Pfam PF08238 Sel1 repeat 838 859 0.37 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SUPERFAMILY SSF81901 180 246 8.5E-12 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SUPERFAMILY SSF81901 874 985 1.24E-31 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SUPERFAMILY SSF81901 556 680 3.27E-34 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SUPERFAMILY SSF81901 703 859 1.48E-36 T 29-03-2018 THSYN_RS06245 06ddca17d8f16f6a2195b9b2efaccdf9 991 SUPERFAMILY SSF81901 405 538 1.74E-32 T 29-03-2018 THSYN_RS07605 8f650ea0daf2977f7bddd8e3ab4e7124 203 Pfam PF14103 Domain of unknown function (DUF4276) 8 187 4.7E-15 T 29-03-2018 IPR025455 Protein of unknown function DUF4276 THSYN_RS21340 10762a5aa056b35f8db94eb6e303b4e6 276 Pfam PF11959 Domain of unknown function (DUF3473) 141 269 1.6E-52 T 29-03-2018 IPR022560 Domain of unknown function DUF3473 THSYN_RS21340 10762a5aa056b35f8db94eb6e303b4e6 276 Gene3D G3DSA:3.20.20.370 1 270 3.3E-41 T 29-03-2018 THSYN_RS21340 10762a5aa056b35f8db94eb6e303b4e6 276 Pfam PF01522 Polysaccharide deacetylase 34 139 1.2E-19 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 THSYN_RS21340 10762a5aa056b35f8db94eb6e303b4e6 276 TIGRFAM TIGR03006 pepcterm_polyde: polysaccharide deacetylase family protein, PEP-CTERM locus subfamily 1 269 1.3E-131 T 29-03-2018 IPR014344 PEP-CTERM locus, polysaccharide deactylase THSYN_RS21340 10762a5aa056b35f8db94eb6e303b4e6 276 SUPERFAMILY SSF88713 7 248 1.0E-40 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS08060 ded5ba57a94e3c12826ed1060e88c465 381 SUPERFAMILY SSF159501 42 283 1.15E-65 T 29-03-2018 THSYN_RS08060 ded5ba57a94e3c12826ed1060e88c465 381 SUPERFAMILY SSF50156 293 367 1.58E-12 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08060 ded5ba57a94e3c12826ed1060e88c465 381 Gene3D G3DSA:3.20.20.140 7 297 0.001 T 29-03-2018 THSYN_RS08060 ded5ba57a94e3c12826ed1060e88c465 381 Pfam PF04187 Haem-binding uptake, Tiki superfamily, ChaN 50 255 1.3E-66 T 29-03-2018 IPR007314 Haem-binding uptake, Tiki superfamily, ChaN THSYN_RS08060 ded5ba57a94e3c12826ed1060e88c465 381 SMART SM00228 294 366 6.1E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS08060 ded5ba57a94e3c12826ed1060e88c465 381 Gene3D G3DSA:2.30.42.10 298 381 3.5E-12 T 29-03-2018 THSYN_RS08060 ded5ba57a94e3c12826ed1060e88c465 381 Pfam PF13180 PDZ domain 295 380 3.5E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS00610 3abde8ae8a6d7d047038d012355dd7e5 207 SUPERFAMILY SSF52200 38 125 1.27E-10 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS00610 3abde8ae8a6d7d047038d012355dd7e5 207 Pfam PF13676 TIR domain 39 154 1.1E-13 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS00610 3abde8ae8a6d7d047038d012355dd7e5 207 Gene3D G3DSA:3.40.50.10140 37 197 4.3E-14 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS10645 914636a55f775586088fc7461a51837d 313 SUPERFAMILY SSF75005 55 235 7.46E-13 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain THSYN_RS10645 914636a55f775586088fc7461a51837d 313 Gene3D G3DSA:2.115.10.20 41 131 0.0043 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain THSYN_RS10645 914636a55f775586088fc7461a51837d 313 Gene3D G3DSA:2.115.10.20 132 289 4.6E-6 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain THSYN_RS19140 21a5530cb2fba8bd7ec4aeaf6918fc97 388 Pfam PF04966 Carbohydrate-selective porin, OprB family 220 388 1.4E-14 T 29-03-2018 IPR007049 Carbohydrate-selective porin OprB GO:0005215|GO:0006810|GO:0016021 THSYN_RS10995 b71d33fec648a0f185fbb70b120f0651 271 SUPERFAMILY SSF52980 22 173 2.68E-13 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS10995 b71d33fec648a0f185fbb70b120f0651 271 Pfam PF05685 Putative restriction endonuclease 22 161 2.7E-9 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS10995 b71d33fec648a0f185fbb70b120f0651 271 Gene3D G3DSA:3.90.1570.10 12 174 2.8E-9 T 29-03-2018 THSYN_RS24580 e7599723c1944e7a7096a2f40f20e83c 525 Pfam PF00361 Proton-conducting membrane transporter 133 428 2.4E-74 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24580 e7599723c1944e7a7096a2f40f20e83c 525 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 64 123 2.6E-6 T 29-03-2018 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24580 e7599723c1944e7a7096a2f40f20e83c 525 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 8 499 1.3E-182 T 29-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24580 e7599723c1944e7a7096a2f40f20e83c 525 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 138 157 4.4E-39 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24580 e7599723c1944e7a7096a2f40f20e83c 525 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 4.4E-39 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24580 e7599723c1944e7a7096a2f40f20e83c 525 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 389 415 4.4E-39 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24580 e7599723c1944e7a7096a2f40f20e83c 525 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 168 192 4.4E-39 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS10335 51c3807343196db589721004bba0291b 443 Pfam PF00501 AMP-binding enzyme 87 293 6.7E-14 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THSYN_RS10335 51c3807343196db589721004bba0291b 443 Gene3D G3DSA:3.40.50.980 98 255 1.2E-17 T 29-03-2018 THSYN_RS10335 51c3807343196db589721004bba0291b 443 Gene3D G3DSA:3.40.50.980 22 97 0.21 T 29-03-2018 THSYN_RS10335 51c3807343196db589721004bba0291b 443 SUPERFAMILY SSF56801 29 404 2.35E-60 T 29-03-2018 THSYN_RS10335 51c3807343196db589721004bba0291b 443 PIRSF PIRSF006444 7 440 3.6E-181 T 29-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 THSYN_RS10335 51c3807343196db589721004bba0291b 443 Pfam PF14535 AMP-binding enzyme C-terminal domain 342 438 1.8E-31 T 29-03-2018 IPR028154 AMP-dependent ligase, C-terminal THSYN_RS10335 51c3807343196db589721004bba0291b 443 Gene3D G3DSA:3.30.300.30 332 441 5.6E-10 T 29-03-2018 THSYN_RS06835 6490b779f4412ced1a59befc90b894fb 142 Gene3D G3DSA:1.20.120.570 3 142 9.1E-4 T 29-03-2018 THSYN_RS06835 6490b779f4412ced1a59befc90b894fb 142 TIGRFAM TIGR01841 phasin: phasin family protein 48 133 4.5E-22 T 29-03-2018 IPR010127 Phasin, subfamily 1 THSYN_RS06835 6490b779f4412ced1a59befc90b894fb 142 Pfam PF09361 Phasin protein 27 125 5.3E-22 T 29-03-2018 IPR018968 Phasin THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 Gene3D G3DSA:1.20.1640.10 788 1009 8.7E-43 T 29-03-2018 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 SUPERFAMILY SSF82714 183 264 2.35E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.1E-65 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 3.1E-65 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.1E-65 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 3.1E-65 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 3.1E-65 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 3.1E-65 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 3.1E-65 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 3.1E-65 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 Gene3D G3DSA:3.30.70.1430 41 141 2.9E-20 T 29-03-2018 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 SUPERFAMILY SSF82693 267 323 5.23E-25 T 29-03-2018 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 SUPERFAMILY SSF82693 137 181 5.23E-25 T 29-03-2018 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 SUPERFAMILY SSF82714 703 785 1.44E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 SUPERFAMILY SSF82866 289 489 9.16E-49 T 29-03-2018 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 SUPERFAMILY SSF82693 43 130 1.94E-18 T 29-03-2018 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 Pfam PF00873 AcrB/AcrD/AcrF family 4 1005 2.1E-257 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 Gene3D G3DSA:1.20.1640.10 280 499 3.7E-46 T 29-03-2018 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 SUPERFAMILY SSF82693 553 650 3.5E-14 T 29-03-2018 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 SUPERFAMILY SSF82866 785 1008 4.32E-46 T 29-03-2018 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 Gene3D G3DSA:3.30.70.1430 555 651 9.1E-5 T 29-03-2018 THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 Gene3D G3DSA:3.30.2090.10 698 787 1.4E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS12280 4c008d97cca8cc2855cdea3d09c72a82 1025 Gene3D G3DSA:3.30.2090.10 181 268 1.2E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS29100 88f7adff20227413ab795fddd07a2982 372 Gene3D G3DSA:3.40.50.2000 207 346 1.4E-43 T 29-03-2018 THSYN_RS29100 88f7adff20227413ab795fddd07a2982 372 SUPERFAMILY SSF53756 7 368 2.87E-129 T 29-03-2018 THSYN_RS29100 88f7adff20227413ab795fddd07a2982 372 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 28 365 1.4E-114 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 THSYN_RS29100 88f7adff20227413ab795fddd07a2982 372 Gene3D G3DSA:3.40.50.2000 7 206 1.6E-71 T 29-03-2018 THSYN_RS29100 88f7adff20227413ab795fddd07a2982 372 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 7 367 1.5E-142 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 THSYN_RS32640 69f95489c3fde6e395228fdfdcc23805 245 Pfam PF03070 TENA/THI-4/PQQC family 16 225 6.0E-59 T 29-03-2018 IPR004305 Thiaminase-2/PQQC THSYN_RS32640 69f95489c3fde6e395228fdfdcc23805 245 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 10 242 4.3E-110 T 29-03-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 THSYN_RS32640 69f95489c3fde6e395228fdfdcc23805 245 Gene3D G3DSA:1.20.910.10 3 244 1.2E-35 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 THSYN_RS32640 69f95489c3fde6e395228fdfdcc23805 245 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 245 129.379 T 29-03-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 THSYN_RS32640 69f95489c3fde6e395228fdfdcc23805 245 SUPERFAMILY SSF48613 7 241 7.91E-74 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 THSYN_RS28210 6b293065d4680af6d28fde1494f42927 511 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 85 294 4.8E-73 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS28210 6b293065d4680af6d28fde1494f42927 511 Gene3D G3DSA:3.40.720.10 292 506 5.3E-35 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS28210 6b293065d4680af6d28fde1494f42927 511 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 7 506 44.472 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS28210 6b293065d4680af6d28fde1494f42927 511 Pfam PF01676 Metalloenzyme superfamily 8 493 1.3E-70 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 THSYN_RS28210 6b293065d4680af6d28fde1494f42927 511 PIRSF PIRSF001492 1 507 1.2E-184 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS28210 6b293065d4680af6d28fde1494f42927 511 SUPERFAMILY SSF53649 304 505 9.38E-66 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS28210 6b293065d4680af6d28fde1494f42927 511 SUPERFAMILY SSF53649 6 80 9.38E-66 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS28210 6b293065d4680af6d28fde1494f42927 511 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 8 505 8.9E-190 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS28210 6b293065d4680af6d28fde1494f42927 511 Gene3D G3DSA:3.40.1450.10 80 291 1.4E-82 T 29-03-2018 THSYN_RS28210 6b293065d4680af6d28fde1494f42927 511 SUPERFAMILY SSF64158 80 303 1.7E-74 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS30050 e817e6f41cc5dc134d7f5934efd78a4d 251 SUPERFAMILY SSF55486 35 96 8.79E-5 T 29-03-2018 THSYN_RS27880 b901b8be03db8c0352e3b38c53d2317e 272 SUPERFAMILY SSF52402 49 235 2.28E-51 T 29-03-2018 THSYN_RS27880 b901b8be03db8c0352e3b38c53d2317e 272 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 76 246 3.6E-49 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 THSYN_RS27880 b901b8be03db8c0352e3b38c53d2317e 272 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 62 269 6.7E-79 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 THSYN_RS27880 b901b8be03db8c0352e3b38c53d2317e 272 Gene3D G3DSA:3.40.50.620 38 271 6.0E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS27880 b901b8be03db8c0352e3b38c53d2317e 272 TIGRFAM TIGR02057 PAPS_reductase: phosphoadenosine phosphosulfate reductase 48 269 5.0E-82 T 29-03-2018 IPR011800 Phosphoadenosine phosphosulphate reductase CysH GO:0004604|GO:0019379 KEGG: 00920+1.8.4.8 THSYN_RS27880 b901b8be03db8c0352e3b38c53d2317e 272 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 36 270 39.097 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 THSYN_RS27880 b901b8be03db8c0352e3b38c53d2317e 272 PIRSF PIRSF000857 29 271 1.3E-53 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 THSYN_RS18600 3818d49a3232128a75892abbf663b0bb 150 SUPERFAMILY SSF50341 1 134 1.7E-21 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS18600 3818d49a3232128a75892abbf663b0bb 150 Gene3D G3DSA:2.30.30.40 84 129 0.0014 T 29-03-2018 THSYN_RS18600 3818d49a3232128a75892abbf663b0bb 150 SMART SM00260 1 133 6.8E-9 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS18600 3818d49a3232128a75892abbf663b0bb 150 Pfam PF01584 CheW-like domain 3 114 4.2E-20 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS18600 3818d49a3232128a75892abbf663b0bb 150 Gene3D G3DSA:2.40.50.180 19 83 2.0E-15 T 29-03-2018 THSYN_RS05875 43f492af81f6cee29407bb1a39cd75ed 409 Pfam PF03781 Sulfatase-modifying factor enzyme 1 176 405 1.0E-50 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS05875 43f492af81f6cee29407bb1a39cd75ed 409 Gene3D G3DSA:3.90.1580.10 237 409 3.6E-48 T 29-03-2018 THSYN_RS05875 43f492af81f6cee29407bb1a39cd75ed 409 Gene3D G3DSA:3.90.1580.10 168 236 1.3E-10 T 29-03-2018 THSYN_RS05875 43f492af81f6cee29407bb1a39cd75ed 409 SUPERFAMILY SSF56436 175 407 3.53E-61 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS29240 1f090484b3d9e2a108ead1da379e05a8 489 SMART SM00382 261 394 5.6E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS29240 1f090484b3d9e2a108ead1da379e05a8 489 SUPERFAMILY SSF52540 226 444 3.91E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29240 1f090484b3d9e2a108ead1da379e05a8 489 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 265 391 1.1E-27 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS29240 1f090484b3d9e2a108ead1da379e05a8 489 Gene3D G3DSA:1.10.8.60 399 478 1.1E-5 T 29-03-2018 THSYN_RS29240 1f090484b3d9e2a108ead1da379e05a8 489 Gene3D G3DSA:3.40.50.300 167 398 9.3E-31 T 29-03-2018 THSYN_RS16180 8689fb3c93c55a194089e2ee7cd6f7ff 300 TIGRFAM TIGR03461 pabC_Proteo: aminodeoxychorismate lyase 26 277 6.0E-71 T 29-03-2018 IPR017824 Aminodeoxychorismate lyase, class IV GO:0008696|GO:0030170|GO:0046656 KEGG: 00790+4.1.3.38|MetaCyc: PWY-6543 THSYN_RS16180 8689fb3c93c55a194089e2ee7cd6f7ff 300 Gene3D G3DSA:3.20.10.10 138 297 1.6E-36 T 29-03-2018 THSYN_RS16180 8689fb3c93c55a194089e2ee7cd6f7ff 300 Gene3D G3DSA:3.30.470.10 27 134 3.4E-21 T 29-03-2018 THSYN_RS16180 8689fb3c93c55a194089e2ee7cd6f7ff 300 Pfam PF01063 Amino-transferase class IV 47 269 1.1E-43 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 THSYN_RS16180 8689fb3c93c55a194089e2ee7cd6f7ff 300 SUPERFAMILY SSF56752 26 278 1.44E-61 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 SUPERFAMILY SSF55874 200 361 1.31E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 252 361 8.2E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 SUPERFAMILY SSF47384 129 210 4.32E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 SMART SM00387 252 364 2.2E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 Gene3D G3DSA:3.30.565.10 214 367 5.6E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 Gene3D G3DSA:1.10.287.130 149 207 1.0E-13 T 29-03-2018 THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 SMART SM00304 69 121 1.8E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 361 1.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 PRINTS PR00344 Bacterial sensor protein C-terminal signature 291 305 1.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 342 1.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 SUPERFAMILY SSF158472 69 117 8.37E-9 T 29-03-2018 THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 SMART SM00388 143 211 1.3E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 Pfam PF00512 His Kinase A (phospho-acceptor) domain 145 209 5.1E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 Pfam PF00672 HAMP domain 69 118 1.7E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS12650 3a183a9ed4e129bd396156093cf52fcf 367 Gene3D G3DSA:3.30.450.20 23 148 3.3E-4 T 29-03-2018 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Gene3D G3DSA:1.25.40.10 705 763 0.062 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Gene3D G3DSA:1.25.40.10 43 120 5.0E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 255 327 1.6E-8 T 29-03-2018 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Gene3D G3DSA:1.25.40.10 284 357 3.0E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Gene3D G3DSA:1.25.40.10 121 205 9.3E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SMART SM00028 64 97 9.8 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SMART SM00028 642 675 0.016 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SMART SM00028 508 541 89.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SMART SM00028 608 641 47.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SMART SM00028 371 404 0.44 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SMART SM00028 304 337 67.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SMART SM00028 819 852 10.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SMART SM00028 236 269 290.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SMART SM00028 474 507 18.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SMART SM00028 751 784 70.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SMART SM00028 542 575 0.98 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SMART SM00028 202 235 22.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SMART SM00028 133 166 2.5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Gene3D G3DSA:1.25.40.10 801 867 1.4E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Gene3D G3DSA:1.25.40.10 764 800 8.1E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Pfam PF14559 Tetratricopeptide repeat 488 542 2.2E-8 T 29-03-2018 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Pfam PF14559 Tetratricopeptide repeat 552 600 2.5E-8 T 29-03-2018 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Pfam PF14559 Tetratricopeptide repeat 795 860 5.7E-8 T 29-03-2018 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SUPERFAMILY SSF48452 137 403 1.03E-26 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SUPERFAMILY SSF48452 749 852 7.05E-34 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SUPERFAMILY SSF48452 450 673 7.05E-34 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Gene3D G3DSA:1.25.40.10 504 557 1.5E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Gene3D G3DSA:1.25.40.10 440 503 5.3E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Gene3D G3DSA:1.25.40.10 558 591 3.1E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Gene3D G3DSA:1.25.40.10 206 283 7.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Pfam PF13432 Tetratricopeptide repeat 615 675 1.2E-7 T 29-03-2018 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Pfam PF13432 Tetratricopeptide repeat 145 199 0.0035 T 29-03-2018 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 TIGRFAM TIGR02917 PEP_TPR_lipo: putative PEP-CTERM system TPR-repeat lipoprotein 36 814 4.2E-110 T 29-03-2018 IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Pfam PF13428 Tetratricopeptide repeat 64 106 4.1E-6 T 29-03-2018 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Gene3D G3DSA:1.25.40.10 358 437 1.4E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 Gene3D G3DSA:1.25.40.10 592 704 9.7E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22355 68f853e95298fd1d43e4fbd4817e0ae8 870 SUPERFAMILY SSF48452 57 114 3.18E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS13330 bee6d8e1e36bb57aed98c05aef716125 718 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 79 103 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 THSYN_RS13330 bee6d8e1e36bb57aed98c05aef716125 718 Gene3D G3DSA:1.10.510.10 66 326 6.6E-47 T 29-03-2018 THSYN_RS13330 bee6d8e1e36bb57aed98c05aef716125 718 SMART SM00220 73 320 2.0E-31 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS13330 bee6d8e1e36bb57aed98c05aef716125 718 SUPERFAMILY SSF56112 64 364 2.29E-56 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS13330 bee6d8e1e36bb57aed98c05aef716125 718 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 188 200 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 THSYN_RS13330 bee6d8e1e36bb57aed98c05aef716125 718 SUPERFAMILY SSF47090 527 586 3.77E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS13330 bee6d8e1e36bb57aed98c05aef716125 718 Gene3D G3DSA:1.10.101.10 525 588 3.1E-11 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS13330 bee6d8e1e36bb57aed98c05aef716125 718 Pfam PF00069 Protein kinase domain 73 272 2.3E-32 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS13330 bee6d8e1e36bb57aed98c05aef716125 718 Pfam PF01471 Putative peptidoglycan binding domain 530 585 4.1E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS04285 2efae771c99767a685cf0380fb9208c5 395 Gene3D G3DSA:3.40.640.10 2 246 2.1E-57 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS04285 2efae771c99767a685cf0380fb9208c5 395 Gene3D G3DSA:3.90.1150.10 247 381 1.4E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS04285 2efae771c99767a685cf0380fb9208c5 395 SUPERFAMILY SSF53383 11 378 7.88E-110 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS04285 2efae771c99767a685cf0380fb9208c5 395 PIRSF PIRSF001434 1 379 3.0E-139 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THSYN_RS04285 2efae771c99767a685cf0380fb9208c5 395 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 377 2.5E-138 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THSYN_RS24060 4f9a1108d212c697f0047a91da7fd108 229 Pfam PF14622 Ribonuclease-III-like 20 137 7.7E-33 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 THSYN_RS24060 4f9a1108d212c697f0047a91da7fd108 229 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 219 29.286 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 THSYN_RS24060 4f9a1108d212c697f0047a91da7fd108 229 ProSitePatterns PS00517 Ribonuclease III family signature. 37 45 - T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 THSYN_RS24060 4f9a1108d212c697f0047a91da7fd108 229 SMART SM00358 155 223 1.4E-21 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain THSYN_RS24060 4f9a1108d212c697f0047a91da7fd108 229 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 10 219 3.1E-69 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 THSYN_RS24060 4f9a1108d212c697f0047a91da7fd108 229 Gene3D G3DSA:1.10.1520.10 1 150 6.3E-40 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 THSYN_RS24060 4f9a1108d212c697f0047a91da7fd108 229 Gene3D G3DSA:3.30.160.20 154 228 1.3E-18 T 29-03-2018 THSYN_RS24060 4f9a1108d212c697f0047a91da7fd108 229 Pfam PF00035 Double-stranded RNA binding motif 155 219 3.2E-13 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain THSYN_RS24060 4f9a1108d212c697f0047a91da7fd108 229 SUPERFAMILY SSF69065 5 157 2.09E-45 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 THSYN_RS24060 4f9a1108d212c697f0047a91da7fd108 229 SUPERFAMILY SSF54768 108 222 8.01E-26 T 29-03-2018 THSYN_RS24060 4f9a1108d212c697f0047a91da7fd108 229 SMART SM00535 20 148 3.2E-48 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 THSYN_RS11300 6229afd7ee017ea68187640aeeeadb5d 189 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 2 186 37.74 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 THSYN_RS11300 6229afd7ee017ea68187640aeeeadb5d 189 Gene3D G3DSA:3.40.50.1950 2 189 4.4E-56 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 THSYN_RS11300 6229afd7ee017ea68187640aeeeadb5d 189 SUPERFAMILY SSF52507 2 186 1.24E-61 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 THSYN_RS11300 6229afd7ee017ea68187640aeeeadb5d 189 Pfam PF02441 Flavoprotein 2 165 5.2E-23 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 THSYN_RS11300 6229afd7ee017ea68187640aeeeadb5d 189 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 3 184 3.9E-70 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 THSYN_RS11485 a7ff2218836e828a2e6ffe41b586c4d7 204 Pfam PF04891 NifQ 50 195 1.1E-48 T 29-03-2018 IPR006975 NifQ GO:0009399|GO:0030151 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 197 207 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 438 448 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Gene3D G3DSA:2.130.10.30 288 433 1.9E-40 T 29-03-2018 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 SUPERFAMILY SSF50985 306 623 3.14E-66 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 245 255 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Gene3D G3DSA:3.10.100.10 479 526 7.9E-18 T 29-03-2018 IPR016186 C-type lectin-like/link domain THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Gene3D G3DSA:3.10.100.10 578 620 7.3E-17 T 29-03-2018 IPR016186 C-type lectin-like/link domain THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Gene3D G3DSA:3.10.100.10 92 141 1.1E-18 T 29-03-2018 IPR016186 C-type lectin-like/link domain THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Gene3D G3DSA:3.10.100.10 621 675 2.2E-12 T 29-03-2018 IPR016186 C-type lectin-like/link domain THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 52 62 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 SUPERFAMILY SSF50985 3 287 1.66E-82 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 115 131 3.4E-18 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 293 309 3.4E-18 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 309 323 3.4E-18 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 164 180 3.4E-18 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 447 468 3.4E-18 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 293 303 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 4 14 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 113 157 2.5E-10 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 403 448 5.9E-11 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 597 639 7.2E-9 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 499 544 1.9E-11 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 643 671 3.4E-5 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 65 110 1.3E-9 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 451 496 3.6E-10 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 258 303 2.8E-10 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 17 62 1.8E-10 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 210 255 2.3E-9 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 161 207 4.7E-10 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 547 592 2.0E-9 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 307 357 1.9E-10 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Gene3D G3DSA:4.10.510.10 527 577 4.1E-17 T 29-03-2018 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Gene3D G3DSA:4.10.510.10 242 287 1.8E-15 T 29-03-2018 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Gene3D G3DSA:4.10.510.10 434 478 1.0E-16 T 29-03-2018 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Gene3D G3DSA:4.10.510.10 49 91 3.1E-15 T 29-03-2018 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Gene3D G3DSA:4.10.510.10 143 192 2.4E-16 T 29-03-2018 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Gene3D G3DSA:4.10.510.10 193 241 3.6E-17 T 29-03-2018 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 Gene3D G3DSA:4.10.510.10 1 48 5.4E-13 T 29-03-2018 THSYN_RS22615 4dae52d41e750dc6247f26b682669df3 676 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 486 496 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 THSYN_RS04785 9e2c7e8095f97968d1ad55bdfebc176a 232 Pfam PF01420 Type I restriction modification DNA specificity domain 45 198 1.1E-14 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS04785 9e2c7e8095f97968d1ad55bdfebc176a 232 Gene3D G3DSA:1.10.287.1120 185 231 5.1E-7 T 29-03-2018 THSYN_RS04785 9e2c7e8095f97968d1ad55bdfebc176a 232 Gene3D G3DSA:3.90.220.20 14 184 1.8E-19 T 29-03-2018 THSYN_RS04785 9e2c7e8095f97968d1ad55bdfebc176a 232 SUPERFAMILY SSF116734 35 219 5.4E-29 T 29-03-2018 THSYN_RS24910 ff24b3899f004edf632920aa2052f2e0 238 SUPERFAMILY SSF55666 153 236 7.46E-23 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THSYN_RS24910 ff24b3899f004edf632920aa2052f2e0 238 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 2.9E-112 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 THSYN_RS24910 ff24b3899f004edf632920aa2052f2e0 238 Pfam PF03725 3' exoribonuclease family, domain 2 159 221 1.9E-7 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THSYN_RS24910 ff24b3899f004edf632920aa2052f2e0 238 SUPERFAMILY SSF54211 1 181 5.06E-47 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS24910 ff24b3899f004edf632920aa2052f2e0 238 Hamap MF_00564 Ribonuclease PH [rph]. 1 237 48.381 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 THSYN_RS24910 ff24b3899f004edf632920aa2052f2e0 238 Gene3D G3DSA:3.30.230.70 1 237 5.0E-56 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THSYN_RS24910 ff24b3899f004edf632920aa2052f2e0 238 ProSitePatterns PS01277 Ribonuclease PH signature. 116 129 - T 29-03-2018 IPR018336 Ribonuclease PH, conserved site THSYN_RS24910 ff24b3899f004edf632920aa2052f2e0 238 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 3.2E-23 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THSYN_RS20885 05d63569dd55e6a223356884d17fe5f9 924 Gene3D G3DSA:1.10.287.130 673 746 8.0E-18 T 29-03-2018 THSYN_RS20885 05d63569dd55e6a223356884d17fe5f9 924 SUPERFAMILY SSF55874 739 911 5.37E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS20885 05d63569dd55e6a223356884d17fe5f9 924 PRINTS PR00344 Bacterial sensor protein C-terminal signature 857 867 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS20885 05d63569dd55e6a223356884d17fe5f9 924 PRINTS PR00344 Bacterial sensor protein C-terminal signature 873 891 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS20885 05d63569dd55e6a223356884d17fe5f9 924 PRINTS PR00344 Bacterial sensor protein C-terminal signature 897 910 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS20885 05d63569dd55e6a223356884d17fe5f9 924 PRINTS PR00344 Bacterial sensor protein C-terminal signature 839 853 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS20885 05d63569dd55e6a223356884d17fe5f9 924 Pfam PF00512 His Kinase A (phospho-acceptor) domain 684 750 1.7E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS20885 05d63569dd55e6a223356884d17fe5f9 924 SMART SM00387 801 913 2.4E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS20885 05d63569dd55e6a223356884d17fe5f9 924 SUPERFAMILY SSF47384 669 751 3.14E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS20885 05d63569dd55e6a223356884d17fe5f9 924 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 802 911 2.5E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS20885 05d63569dd55e6a223356884d17fe5f9 924 Gene3D G3DSA:3.30.565.10 754 923 6.8E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS20885 05d63569dd55e6a223356884d17fe5f9 924 SMART SM00388 683 750 5.5E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 Gene3D G3DSA:1.10.10.10 1245 1306 0.0081 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 SUPERFAMILY SSF48452 1145 1277 2.98E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 Gene3D G3DSA:1.10.150.200 1118 1170 2.6E-11 T 29-03-2018 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 Pfam PF13424 Tetratricopeptide repeat 1123 1191 2.3E-13 T 29-03-2018 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 Pfam PF13424 Tetratricopeptide repeat 1201 1274 2.8E-8 T 29-03-2018 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 Gene3D G3DSA:3.40.50.1460 148 426 8.4E-16 T 29-03-2018 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 SUPERFAMILY SSF48452 1001 1191 9.1E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 Pfam PF12770 CHAT domain 116 411 5.6E-19 T 29-03-2018 IPR024983 CHAT domain THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 SUPERFAMILY SSF52540 463 752 3.27E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 Gene3D G3DSA:3.40.50.300 456 626 5.0E-13 T 29-03-2018 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 Gene3D G3DSA:1.25.40.10 996 1117 2.5E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 SMART SM00028 1122 1155 0.44 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 SMART SM00028 1202 1235 11.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 SMART SM00028 1082 1115 66.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 SMART SM00028 1162 1195 0.026 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 Gene3D G3DSA:3.30.70.100 1171 1204 2.3E-8 T 29-03-2018 THSYN_RS10705 8cbcece7284b29e040ad6df7b1943f51 1451 Gene3D G3DSA:3.30.70.100 1205 1244 1.1E-4 T 29-03-2018 THSYN_RS26450 0a1d82154f4b7ae60a9e97904fe7da01 215 Pfam PF00325 Bacterial regulatory proteins, crp family 171 202 1.7E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS26450 0a1d82154f4b7ae60a9e97904fe7da01 215 Pfam PF00027 Cyclic nucleotide-binding domain 22 109 4.4E-16 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS26450 0a1d82154f4b7ae60a9e97904fe7da01 215 SMART SM00100 2 122 1.2E-10 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS26450 0a1d82154f4b7ae60a9e97904fe7da01 215 SMART SM00419 165 213 1.6E-14 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS26450 0a1d82154f4b7ae60a9e97904fe7da01 215 Gene3D G3DSA:2.60.120.10 4 142 1.1E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS26450 0a1d82154f4b7ae60a9e97904fe7da01 215 Gene3D G3DSA:1.10.10.10 143 212 1.9E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26450 0a1d82154f4b7ae60a9e97904fe7da01 215 SUPERFAMILY SSF51206 10 141 5.63E-23 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like THSYN_RS26450 0a1d82154f4b7ae60a9e97904fe7da01 215 SUPERFAMILY SSF46785 144 212 3.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26450 0a1d82154f4b7ae60a9e97904fe7da01 215 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 171 187 9.0E-8 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS26450 0a1d82154f4b7ae60a9e97904fe7da01 215 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 187 202 9.0E-8 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS26450 0a1d82154f4b7ae60a9e97904fe7da01 215 ProSitePatterns PS00042 Crp-type HTH domain signature. 173 196 - T 29-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 THSYN_RS33180 00cc161cb689d5bf69c465b225ca7c10 313 Pfam PF02634 FdhD/NarQ family 71 305 1.2E-72 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 THSYN_RS33180 00cc161cb689d5bf69c465b225ca7c10 313 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 67 305 2.7E-62 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 THSYN_RS33180 00cc161cb689d5bf69c465b225ca7c10 313 Gene3D G3DSA:3.40.140.10 174 310 3.6E-46 T 29-03-2018 THSYN_RS33180 00cc161cb689d5bf69c465b225ca7c10 313 Gene3D G3DSA:3.10.20.10 73 159 1.9E-17 T 29-03-2018 THSYN_RS33180 00cc161cb689d5bf69c465b225ca7c10 313 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 51 309 33.063 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 THSYN_RS33180 00cc161cb689d5bf69c465b225ca7c10 313 SUPERFAMILY SSF53927 53 306 3.91E-79 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 THSYN_RS33180 00cc161cb689d5bf69c465b225ca7c10 313 PIRSF PIRSF015626 45 310 9.8E-78 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 THSYN_RS06420 d673918f75097776d41efb2c692d7c36 411 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 277 300 6.9E-5 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS06420 d673918f75097776d41efb2c692d7c36 411 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 179 200 6.9E-5 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS06420 d673918f75097776d41efb2c692d7c36 411 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 333 356 6.9E-5 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS06420 d673918f75097776d41efb2c692d7c36 411 Pfam PF02687 FtsX-like permease family 309 404 1.0E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THSYN_RS31270 0196dfc79fc6856b9e961e3a6ad57a74 41 SUPERFAMILY SSF56918 2 41 8.37E-11 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31270 0196dfc79fc6856b9e961e3a6ad57a74 41 Gene3D G3DSA:1.20.5.250 1 41 2.4E-18 T 29-03-2018 THSYN_RS31270 0196dfc79fc6856b9e961e3a6ad57a74 41 PRINTS PR00674 Light harvesting protein B chain signature 3 23 1.5E-6 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31270 0196dfc79fc6856b9e961e3a6ad57a74 41 PRINTS PR00674 Light harvesting protein B chain signature 23 40 1.5E-6 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31270 0196dfc79fc6856b9e961e3a6ad57a74 41 PIRSF PIRSF002900 1 41 2.4E-13 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31270 0196dfc79fc6856b9e961e3a6ad57a74 41 Pfam PF00556 Antenna complex alpha/beta subunit 6 41 1.4E-4 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS00970 556cde2eb64adcabddb64c7400ba1ffb 291 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 286 3.8E-32 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 THSYN_RS00970 556cde2eb64adcabddb64c7400ba1ffb 291 PIRSF PIRSF000103 1 291 1.1E-79 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 THSYN_RS00970 556cde2eb64adcabddb64c7400ba1ffb 291 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 THSYN_RS00970 556cde2eb64adcabddb64c7400ba1ffb 291 Gene3D G3DSA:1.10.1040.10 164 291 2.6E-30 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THSYN_RS00970 556cde2eb64adcabddb64c7400ba1ffb 291 SUPERFAMILY SSF51735 4 163 5.7E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS00970 556cde2eb64adcabddb64c7400ba1ffb 291 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 5 290 4.3E-104 T 29-03-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 THSYN_RS00970 556cde2eb64adcabddb64c7400ba1ffb 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 163 2.4E-50 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 THSYN_RS00970 556cde2eb64adcabddb64c7400ba1ffb 291 Gene3D G3DSA:3.40.50.720 3 163 5.4E-33 T 29-03-2018 THSYN_RS00970 556cde2eb64adcabddb64c7400ba1ffb 291 SUPERFAMILY SSF48179 165 288 8.96E-37 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THSYN_RS07320 91ac813499981748a0b0b312267c5ceb 299 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 155 273 2.4E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS07320 91ac813499981748a0b0b312267c5ceb 299 Gene3D G3DSA:3.40.50.2300 3 155 1.6E-32 T 29-03-2018 THSYN_RS07320 91ac813499981748a0b0b312267c5ceb 299 SMART SM00091 156 222 7.9E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS07320 91ac813499981748a0b0b312267c5ceb 299 Gene3D G3DSA:3.30.450.20 156 296 1.5E-21 T 29-03-2018 THSYN_RS07320 91ac813499981748a0b0b312267c5ceb 299 SUPERFAMILY SSF52172 6 158 4.98E-33 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS07320 91ac813499981748a0b0b312267c5ceb 299 SMART SM00448 7 123 3.6E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS07320 91ac813499981748a0b0b312267c5ceb 299 SMART SM00086 232 274 3.9E-4 T 29-03-2018 IPR001610 PAC motif THSYN_RS07320 91ac813499981748a0b0b312267c5ceb 299 Pfam PF00989 PAS fold 158 271 1.7E-10 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS07320 91ac813499981748a0b0b312267c5ceb 299 SUPERFAMILY SSF55785 147 272 1.03E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS07320 91ac813499981748a0b0b312267c5ceb 299 Pfam PF00072 Response regulator receiver domain 10 123 3.5E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS29835 732512afbe6163fefa22f00b9238ae6f 230 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 216 1.7E-48 T 29-03-2018 IPR010016 KipI family THSYN_RS29835 732512afbe6163fefa22f00b9238ae6f 230 Gene3D G3DSA:2.40.100.10 92 226 4.0E-49 T 29-03-2018 IPR029000 Cyclophilin-like domain THSYN_RS29835 732512afbe6163fefa22f00b9238ae6f 230 SUPERFAMILY SSF50891 95 222 7.59E-43 T 29-03-2018 IPR029000 Cyclophilin-like domain THSYN_RS29835 732512afbe6163fefa22f00b9238ae6f 230 SUPERFAMILY SSF160467 5 99 2.35E-13 T 29-03-2018 THSYN_RS29835 732512afbe6163fefa22f00b9238ae6f 230 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 5 208 8.4E-66 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D THSYN_RS29835 732512afbe6163fefa22f00b9238ae6f 230 Gene3D G3DSA:3.30.1360.40 2 91 1.5E-15 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 THSYN_RS29835 732512afbe6163fefa22f00b9238ae6f 230 SMART SM00796 4 208 6.2E-72 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 Pfam PF00072 Response regulator receiver domain 8 117 7.5E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 Pfam PF08448 PAS fold 165 257 1.7E-6 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 Pfam PF13487 HD domain 506 567 4.1E-18 T 29-03-2018 THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 SUPERFAMILY SSF55785 128 247 7.04E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 Pfam PF13185 GAF domain 286 412 8.6E-14 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 Gene3D G3DSA:3.30.450.20 133 256 1.3E-18 T 29-03-2018 THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 SUPERFAMILY SSF52172 3 148 3.42E-26 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 SMART SM00448 5 117 7.0E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 Gene3D G3DSA:1.10.3210.10 439 619 6.4E-41 T 29-03-2018 THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 SMART SM00471 450 585 3.5E-9 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 138 259 1.9E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 Gene3D G3DSA:3.30.450.40 257 429 8.0E-15 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 SMART SM00091 142 213 0.0026 T 29-03-2018 IPR000014 PAS domain THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 SUPERFAMILY SSF55781 264 417 1.48E-12 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 Gene3D G3DSA:3.40.50.2300 1 132 2.0E-24 T 29-03-2018 THSYN_RS12660 984529fcd3d0133825c1e3edc007a941 636 SUPERFAMILY SSF109604 435 615 1.83E-35 T 29-03-2018 THSYN_RS06030 c62c631991869c89a470a95f48949f64 530 SUPERFAMILY SSF53335 36 242 4.72E-59 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS06030 c62c631991869c89a470a95f48949f64 530 SUPERFAMILY SSF53335 292 396 4.72E-59 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS06030 c62c631991869c89a470a95f48949f64 530 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 116 135 1.3E-17 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS06030 c62c631991869c89a470a95f48949f64 530 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 61 73 1.3E-17 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS06030 c62c631991869c89a470a95f48949f64 530 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 344 358 1.3E-17 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS06030 c62c631991869c89a470a95f48949f64 530 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 321 343 1.3E-17 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS06030 c62c631991869c89a470a95f48949f64 530 PIRSF PIRSF015855 3 439 1.7E-107 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS06030 c62c631991869c89a470a95f48949f64 530 Gene3D G3DSA:3.40.50.150 38 403 5.7E-55 T 29-03-2018 THSYN_RS06030 c62c631991869c89a470a95f48949f64 530 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 64 70 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS06030 c62c631991869c89a470a95f48949f64 530 Pfam PF01555 DNA methylase 61 381 2.8E-35 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THSYN_RS27065 87a131d36155299562f3a3dc6e3d02d6 645 Gene3D G3DSA:1.25.40.10 477 632 7.4E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27065 87a131d36155299562f3a3dc6e3d02d6 645 SUPERFAMILY SSF103642 89 106 5.56E-5 T 29-03-2018 THSYN_RS27065 87a131d36155299562f3a3dc6e3d02d6 645 SMART SM00028 492 525 88.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27065 87a131d36155299562f3a3dc6e3d02d6 645 SMART SM00028 217 250 0.078 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27065 87a131d36155299562f3a3dc6e3d02d6 645 Gene3D G3DSA:3.10.450.50 83 107 5.6E-4 T 29-03-2018 THSYN_RS27065 87a131d36155299562f3a3dc6e3d02d6 645 Pfam PF02810 SEC-C motif 91 105 1.0E-4 T 29-03-2018 IPR004027 SEC-C motif THSYN_RS27065 87a131d36155299562f3a3dc6e3d02d6 645 SUPERFAMILY SSF48452 145 264 1.55E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27065 87a131d36155299562f3a3dc6e3d02d6 645 Gene3D G3DSA:1.25.40.120 120 468 1.8E-10 T 29-03-2018 THSYN_RS27065 87a131d36155299562f3a3dc6e3d02d6 645 SUPERFAMILY SSF48452 476 593 2.93E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS30145 457408fd7e5a4d435a4a069097d5a6a2 585 Pfam PF02195 ParB-like nuclease domain 24 113 1.1E-21 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS30145 457408fd7e5a4d435a4a069097d5a6a2 585 SUPERFAMILY SSF109709 117 206 2.88E-11 T 29-03-2018 THSYN_RS30145 457408fd7e5a4d435a4a069097d5a6a2 585 SUPERFAMILY SSF110849 22 146 8.89E-26 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS30145 457408fd7e5a4d435a4a069097d5a6a2 585 Gene3D G3DSA:3.90.1530.10 11 114 9.4E-32 T 29-03-2018 THSYN_RS30145 457408fd7e5a4d435a4a069097d5a6a2 585 Gene3D G3DSA:1.10.10.730 115 161 1.4E-8 T 29-03-2018 THSYN_RS30145 457408fd7e5a4d435a4a069097d5a6a2 585 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 35 199 8.9E-35 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 THSYN_RS30145 457408fd7e5a4d435a4a069097d5a6a2 585 SMART SM00470 23 114 1.3E-28 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS30145 457408fd7e5a4d435a4a069097d5a6a2 585 TIGRFAM TIGR03734 PRTRC_parB: PRTRC system ParB family protein 33 573 2.3E-122 T 29-03-2018 IPR022396 ParB-related, ThiF-related cassette, ParB THSYN_RS27035 d3f4bf3f3807799edbc3e681e345fae7 88 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 60 9.0E-10 T 29-03-2018 THSYN_RS27035 d3f4bf3f3807799edbc3e681e345fae7 88 Gene3D G3DSA:3.40.1620.10 5 55 4.8E-11 T 29-03-2018 THSYN_RS27035 d3f4bf3f3807799edbc3e681e345fae7 88 SUPERFAMILY SSF143120 6 79 6.8E-17 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS27035 d3f4bf3f3807799edbc3e681e345fae7 88 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 73 2.9E-16 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS07635 9e6af2185c44ef56854a0080380df7a7 280 Pfam PF13432 Tetratricopeptide repeat 88 147 7.1E-5 T 29-03-2018 THSYN_RS07635 9e6af2185c44ef56854a0080380df7a7 280 Pfam PF13181 Tetratricopeptide repeat 50 81 0.018 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS07635 9e6af2185c44ef56854a0080380df7a7 280 Gene3D G3DSA:1.25.40.10 138 269 3.5E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS07635 9e6af2185c44ef56854a0080380df7a7 280 SMART SM00028 50 83 0.18 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS07635 9e6af2185c44ef56854a0080380df7a7 280 SMART SM00028 84 117 0.008 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS07635 9e6af2185c44ef56854a0080380df7a7 280 SMART SM00028 154 187 0.058 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS07635 9e6af2185c44ef56854a0080380df7a7 280 Gene3D G3DSA:1.25.40.10 102 137 2.7E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS07635 9e6af2185c44ef56854a0080380df7a7 280 SUPERFAMILY SSF48452 49 215 1.37E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS07635 9e6af2185c44ef56854a0080380df7a7 280 Pfam PF14559 Tetratricopeptide repeat 164 217 9.0E-6 T 29-03-2018 THSYN_RS07635 9e6af2185c44ef56854a0080380df7a7 280 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 17 261 1.1E-51 T 29-03-2018 IPR013360 Pilus biogenesis/stability type IV, PilW THSYN_RS07635 9e6af2185c44ef56854a0080380df7a7 280 Gene3D G3DSA:1.25.40.10 41 101 1.1E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS07345 3e1764e33da148d458690c29255312ea 779 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 145 1.9E-11 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THSYN_RS07345 3e1764e33da148d458690c29255312ea 779 SUPERFAMILY SSF56935 488 779 3.55E-81 T 29-03-2018 THSYN_RS07345 3e1764e33da148d458690c29255312ea 779 SUPERFAMILY SSF56935 29 329 3.55E-81 T 29-03-2018 THSYN_RS07345 3e1764e33da148d458690c29255312ea 779 SUPERFAMILY SSF56935 360 449 3.55E-81 T 29-03-2018 THSYN_RS07345 3e1764e33da148d458690c29255312ea 779 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 762 779 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site THSYN_RS07345 3e1764e33da148d458690c29255312ea 779 Gene3D G3DSA:2.40.170.20 161 779 1.7E-47 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THSYN_RS07345 3e1764e33da148d458690c29255312ea 779 Gene3D G3DSA:2.170.130.10 19 151 1.3E-14 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THSYN_RS06175 43fd0c677df2c368f33fe35914ec3753 219 PIRSF PIRSF006158 1 217 4.0E-46 T 29-03-2018 IPR016476 SH3 domain protein THSYN_RS06175 43fd0c677df2c368f33fe35914ec3753 219 Gene3D G3DSA:1.20.5.1000 143 184 0.0098 T 29-03-2018 THSYN_RS06175 43fd0c677df2c368f33fe35914ec3753 219 SMART SM00287 16 82 1.8E-5 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type THSYN_RS06175 43fd0c677df2c368f33fe35914ec3753 219 Gene3D G3DSA:2.30.30.410 10 87 2.6E-9 T 29-03-2018 THSYN_RS06175 43fd0c677df2c368f33fe35914ec3753 219 TIGRFAM TIGR04211 SH3_and_anchor: SH3 domain protein 20 216 5.4E-59 T 29-03-2018 IPR016476 SH3 domain protein THSYN_RS06175 43fd0c677df2c368f33fe35914ec3753 219 Pfam PF08239 Bacterial SH3 domain 29 78 3.3E-7 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type THSYN_RS06175 43fd0c677df2c368f33fe35914ec3753 219 Gene3D G3DSA:1.20.5.1070 88 142 7.0E-7 T 29-03-2018 THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 41.986 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 SUPERFAMILY SSF52210 123 287 2.35E-55 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 PIRSF PIRSF001553 1 291 5.5E-127 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 29-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 29-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 Gene3D G3DSA:3.40.50.720 1 119 5.1E-43 T 29-03-2018 THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 2.0E-139 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 Pfam PF00549 CoA-ligase 151 271 2.2E-17 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 SUPERFAMILY SSF51735 1 122 4.97E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 Pfam PF02629 CoA binding domain 7 99 5.7E-28 T 29-03-2018 IPR003781 CoA-binding GO:0048037 THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 SMART SM00881 4 100 3.5E-34 T 29-03-2018 IPR003781 CoA-binding GO:0048037 THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 2.8E-37 T 29-03-2018 THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 2.8E-37 T 29-03-2018 THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 2.8E-37 T 29-03-2018 THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 2.8E-37 T 29-03-2018 THSYN_RS00895 007dd522b1a8d8d572d3b7abf04307d7 291 Gene3D G3DSA:3.40.50.261 120 291 7.9E-54 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THSYN_RS17935 d472a291f0cdc54f8a4c6daba7463f10 156 Pfam PF02082 Transcriptional regulator 1 83 1.3E-25 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type THSYN_RS17935 d472a291f0cdc54f8a4c6daba7463f10 156 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 7.2E-42 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type THSYN_RS17935 d472a291f0cdc54f8a4c6daba7463f10 156 Gene3D G3DSA:1.10.10.10 1 141 3.4E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS17935 d472a291f0cdc54f8a4c6daba7463f10 156 SUPERFAMILY SSF46785 2 132 2.02E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS21000 d2e559187ce9ed0a3f9d996743101128 210 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 2 201 5.1E-57 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 THSYN_RS21000 d2e559187ce9ed0a3f9d996743101128 210 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 6 201 18.959 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 THSYN_RS21000 d2e559187ce9ed0a3f9d996743101128 210 Pfam PF02660 Glycerol-3-phosphate acyltransferase 11 192 6.0E-48 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 THSYN_RS21000 d2e559187ce9ed0a3f9d996743101128 210 SMART SM01207 9 193 1.1E-71 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 THSYN_RS23405 4dd155aa89281dcbe4bf46eb215f9a1f 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 29-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 THSYN_RS23405 4dd155aa89281dcbe4bf46eb215f9a1f 112 SUPERFAMILY SSF54913 1 112 3.02E-44 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THSYN_RS23405 4dd155aa89281dcbe4bf46eb215f9a1f 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.2E-42 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS23405 4dd155aa89281dcbe4bf46eb215f9a1f 112 PRINTS PR00340 P-II protein signature 2 17 3.5E-42 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS23405 4dd155aa89281dcbe4bf46eb215f9a1f 112 PRINTS PR00340 P-II protein signature 52 75 3.5E-42 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS23405 4dd155aa89281dcbe4bf46eb215f9a1f 112 PRINTS PR00340 P-II protein signature 83 103 3.5E-42 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS23405 4dd155aa89281dcbe4bf46eb215f9a1f 112 PRINTS PR00340 P-II protein signature 23 41 3.5E-42 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS23405 4dd155aa89281dcbe4bf46eb215f9a1f 112 PIRSF PIRSF039144 1 112 4.3E-54 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS23405 4dd155aa89281dcbe4bf46eb215f9a1f 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 29-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 THSYN_RS23405 4dd155aa89281dcbe4bf46eb215f9a1f 112 SMART SM00938 4 105 5.4E-66 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS23405 4dd155aa89281dcbe4bf46eb215f9a1f 112 Gene3D G3DSA:3.30.70.120 1 108 6.2E-49 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THSYN_RS29175 11879af71d5e0c1c9791d1d6ba7b84bf 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 155 2.0E-48 T 29-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 THSYN_RS29175 11879af71d5e0c1c9791d1d6ba7b84bf 156 Gene3D G3DSA:1.20.5.620 62 122 4.9E-16 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain THSYN_RS29175 11879af71d5e0c1c9791d1d6ba7b84bf 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 2.9E-33 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THSYN_RS29175 11879af71d5e0c1c9791d1d6ba7b84bf 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 12.569 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THSYN_RS29175 11879af71d5e0c1c9791d1d6ba7b84bf 156 SUPERFAMILY SSF81573 63 121 2.35E-14 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain THSYN_RS25640 6c65ff8b896b294c7f08a13473fea212 160 SMART SM00935 1 156 6.9E-36 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 THSYN_RS25640 6c65ff8b896b294c7f08a13473fea212 160 Gene3D G3DSA:3.30.910.20 1 70 3.3E-10 T 29-03-2018 THSYN_RS25640 6c65ff8b896b294c7f08a13473fea212 160 Gene3D G3DSA:3.30.910.20 71 156 7.5E-15 T 29-03-2018 THSYN_RS25640 6c65ff8b896b294c7f08a13473fea212 160 Pfam PF03938 Outer membrane protein (OmpH-like) 3 155 7.0E-28 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 THSYN_RS25640 6c65ff8b896b294c7f08a13473fea212 160 SUPERFAMILY SSF111384 10 156 5.75E-29 T 29-03-2018 IPR024930 Skp domain THSYN_RS10380 44d1e42b7bf4a80a75bb5b3af68808fb 105 SUPERFAMILY SSF81301 11 105 2.73E-15 T 29-03-2018 THSYN_RS10380 44d1e42b7bf4a80a75bb5b3af68808fb 105 Pfam PF01909 Nucleotidyltransferase domain 10 56 2.4E-9 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS10380 44d1e42b7bf4a80a75bb5b3af68808fb 105 Gene3D G3DSA:3.30.460.10 7 105 4.9E-16 T 29-03-2018 THSYN_RS23215 9a002b9b530d2d495b8d516505c4d414 106 Gene3D G3DSA:2.30.30.110 1 105 7.6E-25 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS23215 9a002b9b530d2d495b8d516505c4d414 106 PIRSF PIRSF033490 1 106 3.0E-28 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS23215 9a002b9b530d2d495b8d516505c4d414 106 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 103 7.2E-24 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS23215 9a002b9b530d2d495b8d516505c4d414 106 SUPERFAMILY SSF50118 2 105 8.07E-29 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS21565 93feb2a4c5370a17a2328eb4251bc1a8 77 Gene3D G3DSA:1.10.1220.10 1 41 2.2E-8 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS30595 6b0e236bbdc7484d0d9ff5776cc59ca8 251 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS30595 6b0e236bbdc7484d0d9ff5776cc59ca8 251 PIRSF PIRSF039137 6 243 9.0E-103 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 THSYN_RS30595 6b0e236bbdc7484d0d9ff5776cc59ca8 251 Gene3D G3DSA:3.40.50.300 7 248 2.3E-57 T 29-03-2018 THSYN_RS30595 6b0e236bbdc7484d0d9ff5776cc59ca8 251 SUPERFAMILY SSF52540 10 241 5.44E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30595 6b0e236bbdc7484d0d9ff5776cc59ca8 251 Pfam PF00005 ABC transporter 26 170 5.2E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS30595 6b0e236bbdc7484d0d9ff5776cc59ca8 251 SMART SM00382 35 221 4.5E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS21530 6d9e436fb618f0c87b18818c091b9422 1146 SUPERFAMILY SSF50182 957 1022 3.17E-18 T 29-03-2018 IPR010920 LSM domain THSYN_RS21530 6d9e436fb618f0c87b18818c091b9422 1146 SUPERFAMILY SSF82861 875 955 2.75E-6 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 THSYN_RS21530 6d9e436fb618f0c87b18818c091b9422 1146 Pfam PF12795 Mechanosensitive ion channel porin domain 49 286 4.0E-38 T 29-03-2018 IPR024393 Mechanosensitive ion channel MscS, porin domain THSYN_RS21530 6d9e436fb618f0c87b18818c091b9422 1146 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 515 853 2.4E-89 T 29-03-2018 IPR025692 Mechanosensitive ion channel inner membrane domain 1 THSYN_RS21530 6d9e436fb618f0c87b18818c091b9422 1146 Gene3D G3DSA:1.20.5.320 89 207 4.8E-7 T 29-03-2018 THSYN_RS21530 6d9e436fb618f0c87b18818c091b9422 1146 Gene3D G3DSA:3.30.70.100 1024 1118 4.1E-18 T 29-03-2018 THSYN_RS21530 6d9e436fb618f0c87b18818c091b9422 1146 Gene3D G3DSA:2.30.30.60 972 1021 9.5E-14 T 29-03-2018 THSYN_RS21530 6d9e436fb618f0c87b18818c091b9422 1146 Pfam PF00924 Mechanosensitive ion channel 914 1113 1.1E-54 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THSYN_RS21530 6d9e436fb618f0c87b18818c091b9422 1146 SUPERFAMILY SSF82689 1027 1122 1.31E-23 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 THSYN_RS21530 6d9e436fb618f0c87b18818c091b9422 1146 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 986 1020 - T 29-03-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 THSYN_RS07085 63029be1247d1eb5b277da5e90b48b70 787 SUPERFAMILY SSF53649 65 601 1.34E-119 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS07085 63029be1247d1eb5b277da5e90b48b70 787 Pfam PF00884 Sulfatase 66 484 1.9E-80 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THSYN_RS07085 63029be1247d1eb5b277da5e90b48b70 787 Gene3D G3DSA:2.60.120.200 622 785 1.7E-7 T 29-03-2018 THSYN_RS07085 63029be1247d1eb5b277da5e90b48b70 787 ProSitePatterns PS00523 Sulfatases signature 1. 110 122 - T 29-03-2018 IPR024607 Sulfatase, conserved site THSYN_RS07085 63029be1247d1eb5b277da5e90b48b70 787 Gene3D G3DSA:3.30.1120.10 514 610 4.8E-12 T 29-03-2018 THSYN_RS07085 63029be1247d1eb5b277da5e90b48b70 787 Gene3D G3DSA:3.40.720.10 63 513 9.5E-90 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS10905 547e51e2d49565cd509962a3abb3878b 260 Gene3D G3DSA:3.30.70.580 1 107 4.0E-34 T 29-03-2018 THSYN_RS10905 547e51e2d49565cd509962a3abb3878b 260 PIRSF PIRSF001430 3 256 4.6E-75 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS10905 547e51e2d49565cd509962a3abb3878b 260 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 240 1.2E-66 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS10905 547e51e2d49565cd509962a3abb3878b 260 Pfam PF01416 tRNA pseudouridine synthase 145 247 3.7E-29 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS10905 547e51e2d49565cd509962a3abb3878b 260 Pfam PF01416 tRNA pseudouridine synthase 11 105 1.1E-9 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS10905 547e51e2d49565cd509962a3abb3878b 260 SUPERFAMILY SSF55120 4 253 1.02E-87 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS10905 547e51e2d49565cd509962a3abb3878b 260 Gene3D G3DSA:3.30.70.660 108 245 1.7E-35 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS10905 547e51e2d49565cd509962a3abb3878b 260 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 4 246 33.974 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS11470 3da8bfb78b0167d93136226bcc496f8d 172 SUPERFAMILY SSF52200 1 51 4.71E-9 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS11470 3da8bfb78b0167d93136226bcc496f8d 172 Gene3D G3DSA:3.40.50.10140 1 89 1.3E-9 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS11470 3da8bfb78b0167d93136226bcc496f8d 172 Pfam PF13676 TIR domain 2 52 1.4E-6 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS21830 d3e5625fd85fc997ce763fb83feaedb9 497 Gene3D G3DSA:1.20.1600.10 10 458 2.1E-98 T 29-03-2018 THSYN_RS21830 d3e5625fd85fc997ce763fb83feaedb9 497 SUPERFAMILY SSF56954 3 454 1.57E-106 T 29-03-2018 THSYN_RS21830 d3e5625fd85fc997ce763fb83feaedb9 497 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 2 452 9.7E-113 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 THSYN_RS21830 d3e5625fd85fc997ce763fb83feaedb9 497 Pfam PF02321 Outer membrane efflux protein 271 450 2.5E-21 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THSYN_RS21830 d3e5625fd85fc997ce763fb83feaedb9 497 Pfam PF02321 Outer membrane efflux protein 51 243 3.7E-26 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Pfam PF08447 PAS fold 1037 1125 3.2E-11 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Pfam PF08447 PAS fold 387 474 1.2E-18 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Gene3D G3DSA:1.10.287.130 1273 1302 4.1E-10 T 29-03-2018 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 488 612 7.0E-19 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 743 862 1.3E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 1139 1266 1.1E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 614 742 2.2E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 882 1009 1.1E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 360 487 6.6E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SUPERFAMILY SSF55785 602 733 5.23E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SUPERFAMILY SSF55785 352 478 2.09E-20 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SUPERFAMILY SSF55785 477 603 5.39E-26 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM01079 83 280 1.3E-47 T 29-03-2018 IPR006189 CHASE domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Pfam PF00989 PAS fold 1145 1245 2.4E-6 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Gene3D G3DSA:3.30.450.20 609 743 3.2E-24 T 29-03-2018 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Gene3D G3DSA:3.30.450.20 876 1002 4.7E-23 T 29-03-2018 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Gene3D G3DSA:3.30.450.20 349 482 8.5E-29 T 29-03-2018 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Gene3D G3DSA:3.30.450.20 1003 1133 1.4E-24 T 29-03-2018 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Gene3D G3DSA:3.30.450.20 483 608 1.1E-29 T 29-03-2018 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Gene3D G3DSA:3.30.450.20 1134 1272 1.9E-24 T 29-03-2018 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SUPERFAMILY SSF55785 1128 1258 2.42E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SUPERFAMILY SSF55785 733 853 7.4E-20 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00086 693 735 79.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00086 814 855 330.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00086 964 1002 140.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00086 1089 1131 4.5 T 29-03-2018 IPR001610 PAC motif THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00086 1223 1260 5.1 T 29-03-2018 IPR001610 PAC motif THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00086 438 480 4.6 T 29-03-2018 IPR001610 PAC motif THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00086 563 605 0.16 T 29-03-2018 IPR001610 PAC motif THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Gene3D G3DSA:3.30.450.20 744 875 2.2E-23 T 29-03-2018 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Pfam PF03924 CHASE domain 86 267 1.3E-42 T 29-03-2018 IPR006189 CHASE domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1273 1301 4.0E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SUPERFAMILY SSF55785 999 1129 6.28E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SUPERFAMILY SSF55785 877 1000 1.68E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SUPERFAMILY SSF47384 1259 1301 8.44E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00091 885 951 0.0073 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00091 743 809 3.2E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00091 1014 1082 7.9 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00091 617 686 0.034 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00091 364 432 9.4E-4 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00091 1143 1209 2.1E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 SMART SM00091 492 557 0.49 T 29-03-2018 IPR000014 PAS domain THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Pfam PF08448 PAS fold 623 737 1.3E-9 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Pfam PF08448 PAS fold 750 853 6.3E-11 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Pfam PF08448 PAS fold 499 604 6.9E-15 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS14850 a5e3845212c15e4278022741865a3d3f 1306 Pfam PF08448 PAS fold 892 1004 1.9E-8 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS25380 6e2c8a69937d74a024e165bded32a51e 124 TIGRFAM TIGR04176 MarR_EPS: EPS-associated transcriptional regulator, MarR family 10 107 1.9E-40 T 29-03-2018 IPR026433 EPS-associated transcriptional regulator, MarR family THSYN_RS25380 6e2c8a69937d74a024e165bded32a51e 124 Gene3D G3DSA:1.10.10.10 1 109 4.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25380 6e2c8a69937d74a024e165bded32a51e 124 Pfam PF13412 Winged helix-turn-helix DNA-binding 11 55 5.6E-9 T 29-03-2018 THSYN_RS25380 6e2c8a69937d74a024e165bded32a51e 124 SUPERFAMILY SSF46785 6 87 2.73E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS32310 bb04ce40e33c96abb938006f33eabb80 430 SUPERFAMILY SSF52540 6 193 1.45E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS32310 bb04ce40e33c96abb938006f33eabb80 430 Gene3D G3DSA:3.40.50.880 192 399 4.0E-21 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS32310 bb04ce40e33c96abb938006f33eabb80 430 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 9 185 1.1E-13 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THSYN_RS32310 bb04ce40e33c96abb938006f33eabb80 430 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 239 419 8.6E-30 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 THSYN_RS32310 bb04ce40e33c96abb938006f33eabb80 430 Gene3D G3DSA:3.40.50.300 3 190 4.7E-27 T 29-03-2018 THSYN_RS32310 bb04ce40e33c96abb938006f33eabb80 430 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 5 421 37.163 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 THSYN_RS32310 bb04ce40e33c96abb938006f33eabb80 430 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 9 426 2.5E-78 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 THSYN_RS32310 bb04ce40e33c96abb938006f33eabb80 430 SUPERFAMILY SSF52317 237 428 9.33E-30 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 Gene3D G3DSA:1.10.287.730 162 188 6.4E-12 T 29-03-2018 THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 Gene3D G3DSA:3.30.70.1170 189 246 1.4E-14 T 29-03-2018 THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 Gene3D G3DSA:1.10.940.10 17 160 6.4E-26 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 SUPERFAMILY SSF53335 158 450 2.74E-72 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 23 449 3.0E-117 T 29-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 Pfam PF01189 16S rRNA methyltransferase RsmB/F 256 447 5.8E-57 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 334 346 5.4E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 432 449 5.4E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 384 400 5.4E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 267 277 5.4E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 238 252 5.4E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 SUPERFAMILY SSF48013 21 165 3.43E-28 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 333 344 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 Gene3D G3DSA:3.40.50.150 247 452 5.9E-60 T 29-03-2018 THSYN_RS20610 7eba32de3ca6e56661169e647a1a3205 452 Pfam PF01029 NusB family 21 142 2.2E-18 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THSYN_RS20640 c17a2c746ae2538e9a0db7fcba133be8 496 Pfam PF13635 Domain of unknown function (DUF4143) 260 411 7.2E-9 T 29-03-2018 IPR025420 Domain of unknown function DUF4143 THSYN_RS20640 c17a2c746ae2538e9a0db7fcba133be8 496 SUPERFAMILY SSF52540 46 190 1.94E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS20640 c17a2c746ae2538e9a0db7fcba133be8 496 Gene3D G3DSA:1.10.10.10 251 335 2.0E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS20640 c17a2c746ae2538e9a0db7fcba133be8 496 Pfam PF13173 AAA domain 52 185 5.3E-29 T 29-03-2018 THSYN_RS04800 f515a2ef1f7bd8366b33fe2e5a2fc57f 826 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 266 272 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS04800 f515a2ef1f7bd8366b33fe2e5a2fc57f 826 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 300 324 6.6E-18 T 29-03-2018 THSYN_RS04800 f515a2ef1f7bd8366b33fe2e5a2fc57f 826 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 163 179 6.6E-18 T 29-03-2018 THSYN_RS04800 f515a2ef1f7bd8366b33fe2e5a2fc57f 826 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 263 275 6.6E-18 T 29-03-2018 THSYN_RS04800 f515a2ef1f7bd8366b33fe2e5a2fc57f 826 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 192 206 6.6E-18 T 29-03-2018 THSYN_RS04800 f515a2ef1f7bd8366b33fe2e5a2fc57f 826 Gene3D G3DSA:3.40.50.150 161 445 2.0E-55 T 29-03-2018 THSYN_RS04800 f515a2ef1f7bd8366b33fe2e5a2fc57f 826 Pfam PF12161 HsdM N-terminal domain 8 124 3.9E-13 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS04800 f515a2ef1f7bd8366b33fe2e5a2fc57f 826 SUPERFAMILY SSF53335 6 488 1.13E-118 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS04800 f515a2ef1f7bd8366b33fe2e5a2fc57f 826 Pfam PF02384 N-6 DNA Methylase 139 450 3.1E-95 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS22965 f12b5d2c1fb56234f0e33fdcf0e34041 133 SUPERFAMILY SSF88723 1 127 3.92E-16 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS22965 f12b5d2c1fb56234f0e33fdcf0e34041 133 Pfam PF01850 PIN domain 1 120 7.1E-12 T 29-03-2018 IPR002716 PIN domain THSYN_RS22965 f12b5d2c1fb56234f0e33fdcf0e34041 133 Gene3D G3DSA:3.40.50.1010 1 129 9.2E-13 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS22965 f12b5d2c1fb56234f0e33fdcf0e34041 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 130 11.214 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS20560 887a6dddf2e3cae0f98483670bf7e6ca 171 Gene3D G3DSA:3.90.1580.10 124 167 3.1E-7 T 29-03-2018 THSYN_RS20560 887a6dddf2e3cae0f98483670bf7e6ca 171 Gene3D G3DSA:3.90.1580.10 59 123 9.3E-15 T 29-03-2018 THSYN_RS20560 887a6dddf2e3cae0f98483670bf7e6ca 171 SUPERFAMILY SSF56436 67 165 5.89E-24 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS20560 887a6dddf2e3cae0f98483670bf7e6ca 171 Pfam PF03781 Sulfatase-modifying factor enzyme 1 69 165 1.3E-15 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 Gene3D G3DSA:3.20.20.10 34 265 3.4E-62 T 29-03-2018 IPR029066 PLP-binding barrel THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 225 241 - T 29-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 164 173 8.0E-33 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 75 92 8.0E-33 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 298 316 8.0E-33 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 379 401 8.0E-33 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 SUPERFAMILY SSF50621 253 411 3.56E-56 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 57 75 - T 29-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 Gene3D G3DSA:2.40.37.10 266 412 1.7E-47 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 412 42.478 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 SUPERFAMILY SSF51419 26 282 2.33E-81 T 29-03-2018 IPR029066 PLP-binding barrel THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 411 5.5E-161 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 35 280 6.5E-73 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 57 75 7.5E-26 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 369 382 7.5E-26 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 190 203 7.5E-26 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 270 289 7.5E-26 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 77 89 7.5E-26 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THSYN_RS02565 244753d370b22f3d774b2a49441258e9 415 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 29 368 6.2E-24 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 THSYN_RS32135 d3130a76c4d0f2ef453f6257fa787e9f 294 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 21 249 7.6E-58 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 THSYN_RS32135 d3130a76c4d0f2ef453f6257fa787e9f 294 Gene3D G3DSA:3.40.50.620 1 291 8.4E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS32135 d3130a76c4d0f2ef453f6257fa787e9f 294 PIRSF PIRSF002936 1 294 2.7E-138 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 THSYN_RS32135 d3130a76c4d0f2ef453f6257fa787e9f 294 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 2 294 9.5E-145 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 THSYN_RS32135 d3130a76c4d0f2ef453f6257fa787e9f 294 SUPERFAMILY SSF52402 3 201 2.14E-68 T 29-03-2018 THSYN_RS18485 5c2c4b7f3f5d1139351c58adefa59335 158 Pfam PF03350 Uncharacterized protein family, UPF0114 6 122 1.0E-21 T 29-03-2018 IPR005134 Uncharacterised protein family UPF0114 THSYN_RS18485 5c2c4b7f3f5d1139351c58adefa59335 158 PIRSF PIRSF026509 1 158 4.1E-46 T 29-03-2018 IPR005134 Uncharacterised protein family UPF0114 THSYN_RS01905 42b9b08d7180d09c559d2a5726c7b043 216 Gene3D G3DSA:3.40.80.10 2 189 5.8E-50 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 THSYN_RS01905 42b9b08d7180d09c559d2a5726c7b043 216 SUPERFAMILY SSF55846 5 183 3.93E-62 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 THSYN_RS01905 42b9b08d7180d09c559d2a5726c7b043 216 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 28 170 8.9E-24 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 THSYN_RS01905 42b9b08d7180d09c559d2a5726c7b043 216 SMART SM00644 17 169 1.0E-42 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 THSYN_RS27260 8dc028a7d3f0973bb30933d1a576c679 228 Pfam PF05063 MT-A70 24 194 3.5E-32 T 29-03-2018 IPR007757 MT-A70-like GO:0006139|GO:0008168 THSYN_RS27260 8dc028a7d3f0973bb30933d1a576c679 228 SUPERFAMILY SSF53335 21 185 1.55E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS27260 8dc028a7d3f0973bb30933d1a576c679 228 Gene3D G3DSA:3.40.50.150 14 204 8.8E-7 T 29-03-2018 THSYN_RS27260 8dc028a7d3f0973bb30933d1a576c679 228 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 27 33 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS21790 4d97697dfd93db56af32d4c5ae376070 336 Gene3D G3DSA:3.40.50.2000 159 316 2.2E-26 T 29-03-2018 THSYN_RS21790 4d97697dfd93db56af32d4c5ae376070 336 SUPERFAMILY SSF53756 63 327 5.76E-34 T 29-03-2018 THSYN_RS21790 4d97697dfd93db56af32d4c5ae376070 336 Pfam PF00534 Glycosyl transferases group 1 227 308 1.3E-16 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS32165 4367b3ac29b6d8713d9bd0b6cb8bba93 253 Pfam PF11760 Cobalamin synthesis G N-terminal 62 139 3.7E-31 T 29-03-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 THSYN_RS32165 4367b3ac29b6d8713d9bd0b6cb8bba93 253 SUPERFAMILY SSF159672 4 193 3.92E-52 T 29-03-2018 THSYN_RS32165 4367b3ac29b6d8713d9bd0b6cb8bba93 253 Pfam PF11761 Cobalamin biosynthesis central region 145 182 3.1E-9 T 29-03-2018 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 THSYN_RS21350 13c6aea6c4be30024e4487e10484a7ee 345 Pfam PF13401 AAA domain 41 171 5.9E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS21350 13c6aea6c4be30024e4487e10484a7ee 345 TIGRFAM TIGR03015 pepcterm_ATPase: putative secretion ATPase, PEP-CTERM locus subfamily 1 269 9.9E-111 T 29-03-2018 IPR017466 ATPase, secretion system, PEP-CTERM, predicted THSYN_RS21350 13c6aea6c4be30024e4487e10484a7ee 345 SMART SM00382 42 208 0.0041 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS21350 13c6aea6c4be30024e4487e10484a7ee 345 Gene3D G3DSA:3.40.50.300 27 243 1.1E-10 T 29-03-2018 THSYN_RS21350 13c6aea6c4be30024e4487e10484a7ee 345 SUPERFAMILY SSF52540 5 264 3.54E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31630 29565eedd990e9ab9723cba9ea1c9d62 75 Pfam PF04255 Protein of unknown function (DUF433) 7 62 3.7E-26 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS31630 29565eedd990e9ab9723cba9ea1c9d62 75 SUPERFAMILY SSF46689 1 68 1.45E-23 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS31630 29565eedd990e9ab9723cba9ea1c9d62 75 Gene3D G3DSA:1.10.10.10 7 68 4.3E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS31810 5859f2b5d79058b8c371d85830fceaf1 407 Gene3D G3DSA:1.20.1250.20 2 168 4.5E-12 T 29-03-2018 THSYN_RS31810 5859f2b5d79058b8c371d85830fceaf1 407 Pfam PF03209 PUCC protein 1 389 2.7E-88 T 29-03-2018 IPR004896 PucC-related THSYN_RS31810 5859f2b5d79058b8c371d85830fceaf1 407 SUPERFAMILY SSF103473 8 388 2.22E-25 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS31810 5859f2b5d79058b8c371d85830fceaf1 407 Gene3D G3DSA:1.20.1250.20 176 384 1.4E-12 T 29-03-2018 THSYN_RS31810 5859f2b5d79058b8c371d85830fceaf1 407 PIRSF PIRSF016565 1 406 3.9E-112 T 29-03-2018 IPR026036 PucC protein THSYN_RS16830 599debab5791f037fe747915b054d4ff 605 Pfam PF13537 Glutamine amidotransferase domain 48 165 4.5E-41 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain THSYN_RS16830 599debab5791f037fe747915b054d4ff 605 Gene3D G3DSA:3.40.50.620 221 588 2.0E-70 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS16830 599debab5791f037fe747915b054d4ff 605 Pfam PF00733 Asparagine synthase 239 585 1.6E-84 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THSYN_RS16830 599debab5791f037fe747915b054d4ff 605 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 522 6.3E-128 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS16830 599debab5791f037fe747915b054d4ff 605 SUPERFAMILY SSF56235 1 222 2.23E-57 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS16830 599debab5791f037fe747915b054d4ff 605 PIRSF PIRSF001589 1 603 6.8E-182 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS16830 599debab5791f037fe747915b054d4ff 605 SUPERFAMILY SSF52402 231 381 4.47E-72 T 29-03-2018 THSYN_RS16830 599debab5791f037fe747915b054d4ff 605 SUPERFAMILY SSF52402 442 565 4.47E-72 T 29-03-2018 THSYN_RS16830 599debab5791f037fe747915b054d4ff 605 Gene3D G3DSA:3.60.20.10 1 220 1.6E-53 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS11015 7b048f8c2d8fde6dd0c75d4799664520 242 SUPERFAMILY SSF52540 1 234 8.64E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11015 7b048f8c2d8fde6dd0c75d4799664520 242 SMART SM00382 26 213 1.2E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS11015 7b048f8c2d8fde6dd0c75d4799664520 242 Pfam PF00005 ABC transporter 19 165 4.2E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS11015 7b048f8c2d8fde6dd0c75d4799664520 242 PIRSF PIRSF039085 1 241 1.5E-104 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THSYN_RS11015 7b048f8c2d8fde6dd0c75d4799664520 242 Gene3D G3DSA:3.40.50.300 1 242 1.7E-69 T 29-03-2018 THSYN_RS11015 7b048f8c2d8fde6dd0c75d4799664520 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 142 171 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 Gene3D G3DSA:3.30.559.10 309 552 3.8E-80 T 29-03-2018 THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 Gene3D G3DSA:4.10.320.10 245 306 2.6E-17 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 SUPERFAMILY SSF52777 311 552 8.9E-84 T 29-03-2018 THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 89 552 4.4E-186 T 29-03-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 Pfam PF02817 e3 binding domain 253 287 3.6E-13 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 Gene3D G3DSA:2.40.50.100 1 57 4.0E-9 T 29-03-2018 THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 325 551 7.5E-77 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 SUPERFAMILY SSF51230 118 211 1.7E-22 T 29-03-2018 IPR011053 Single hybrid motif THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 SUPERFAMILY SSF47005 249 291 5.36E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 SUPERFAMILY SSF51230 5 95 4.58E-22 T 29-03-2018 IPR011053 Single hybrid motif THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 Gene3D G3DSA:2.40.50.100 148 192 5.7E-13 T 29-03-2018 THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 Pfam PF00364 Biotin-requiring enzyme 121 191 7.3E-21 T 29-03-2018 IPR000089 Biotin/lipoyl attachment THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 Pfam PF00364 Biotin-requiring enzyme 6 77 1.6E-19 T 29-03-2018 IPR000089 Biotin/lipoyl attachment THSYN_RS01175 55806ee5a0d27f6d0d1653cf020d940b 552 Gene3D G3DSA:3.90.1170.30 58 147 4.0E-20 T 29-03-2018 THSYN_RS22040 023be2118a96296e13fa8dbbfad6d129 251 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 226 2.0E-103 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS22040 023be2118a96296e13fa8dbbfad6d129 251 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 THSYN_RS22040 023be2118a96296e13fa8dbbfad6d129 251 Gene3D G3DSA:3.40.50.10490 5 249 1.3E-93 T 29-03-2018 THSYN_RS22040 023be2118a96296e13fa8dbbfad6d129 251 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 THSYN_RS22040 023be2118a96296e13fa8dbbfad6d129 251 Pfam PF00318 Ribosomal protein S2 9 224 1.9E-94 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS22040 023be2118a96296e13fa8dbbfad6d129 251 PRINTS PR00395 Ribosomal protein S2 signature 87 104 3.5E-37 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS22040 023be2118a96296e13fa8dbbfad6d129 251 PRINTS PR00395 Ribosomal protein S2 signature 158 175 3.5E-37 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS22040 023be2118a96296e13fa8dbbfad6d129 251 PRINTS PR00395 Ribosomal protein S2 signature 175 186 3.5E-37 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS22040 023be2118a96296e13fa8dbbfad6d129 251 PRINTS PR00395 Ribosomal protein S2 signature 37 46 3.5E-37 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS22040 023be2118a96296e13fa8dbbfad6d129 251 PRINTS PR00395 Ribosomal protein S2 signature 6 24 3.5E-37 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS22040 023be2118a96296e13fa8dbbfad6d129 251 PRINTS PR00395 Ribosomal protein S2 signature 196 210 3.5E-37 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS22040 023be2118a96296e13fa8dbbfad6d129 251 SUPERFAMILY SSF52313 6 229 2.75E-94 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain THSYN_RS22040 023be2118a96296e13fa8dbbfad6d129 251 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 41.961 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS30945 44745de4590db5ccd0ae97d8ed7a7d36 660 Gene3D G3DSA:1.20.144.10 266 455 2.8E-7 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS30945 44745de4590db5ccd0ae97d8ed7a7d36 660 SUPERFAMILY SSF48317 265 441 1.05E-16 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS30945 44745de4590db5ccd0ae97d8ed7a7d36 660 Pfam PF14067 LssY C-terminus 500 611 2.9E-13 T 29-03-2018 IPR025902 LssY-like C-terminal domain THSYN_RS30945 44745de4590db5ccd0ae97d8ed7a7d36 660 Pfam PF09335 SNARE associated Golgi protein 39 162 1.3E-15 T 29-03-2018 IPR032816 SNARE associated Golgi protein THSYN_RS07090 8886a3da664af720b2934be93c192b9f 217 Pfam PF05235 CHAD domain 39 121 5.6E-18 T 29-03-2018 IPR007899 CHAD domain THSYN_RS07090 8886a3da664af720b2934be93c192b9f 217 SMART SM00880 20 178 4.0E-5 T 29-03-2018 IPR007899 CHAD domain THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 SUPERFAMILY SSF82693 137 183 8.89E-21 T 29-03-2018 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 SUPERFAMILY SSF82693 276 332 8.89E-21 T 29-03-2018 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 SUPERFAMILY SSF82866 298 498 1.19E-46 T 29-03-2018 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 Gene3D G3DSA:3.30.70.1440 671 764 1.2E-14 T 29-03-2018 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 Gene3D G3DSA:3.30.2090.10 182 277 1.6E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 Gene3D G3DSA:1.20.1640.10 845 1033 1.7E-33 T 29-03-2018 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 Gene3D G3DSA:1.20.1640.10 288 508 1.4E-44 T 29-03-2018 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 SUPERFAMILY SSF82693 39 129 6.28E-22 T 29-03-2018 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 1.0E-93 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 1.0E-93 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 1.0E-93 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 1.0E-93 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 1.0E-93 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 1.0E-93 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 1.0E-93 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 1.0E-93 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 1.0E-93 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 SUPERFAMILY SSF82866 805 1028 6.93E-48 T 29-03-2018 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 Gene3D G3DSA:3.30.70.1430 566 667 4.9E-15 T 29-03-2018 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 Gene3D G3DSA:3.30.70.1320 765 844 5.2E-8 T 29-03-2018 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 Pfam PF00873 AcrB/AcrD/AcrF family 2 1026 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 SUPERFAMILY SSF82693 564 670 1.33E-24 T 29-03-2018 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 Gene3D G3DSA:3.30.70.1430 39 141 7.9E-22 T 29-03-2018 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 2 1034 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 SUPERFAMILY SSF82714 184 273 8.37E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS21825 ca187e2fe1297b2f154696aa3cc24dc7 1073 SUPERFAMILY SSF82714 722 806 1.31E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS08830 09ebb36ea5e6e39403a21ac275e1bdfa 210 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 7 207 2.0E-58 T 29-03-2018 THSYN_RS08830 09ebb36ea5e6e39403a21ac275e1bdfa 210 Gene3D G3DSA:3.40.50.150 1 210 1.9E-37 T 29-03-2018 THSYN_RS08830 09ebb36ea5e6e39403a21ac275e1bdfa 210 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 2 209 34.582 T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THSYN_RS08830 09ebb36ea5e6e39403a21ac275e1bdfa 210 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 2 209 8.1E-66 T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THSYN_RS08830 09ebb36ea5e6e39403a21ac275e1bdfa 210 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 132 147 - T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THSYN_RS08830 09ebb36ea5e6e39403a21ac275e1bdfa 210 SUPERFAMILY SSF53335 17 208 7.06E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS12810 28e167f20f79cb05ee05d993b23e42d7 182 SUPERFAMILY SSF54637 3 152 2.55E-47 T 29-03-2018 IPR029069 HotDog domain THSYN_RS12810 28e167f20f79cb05ee05d993b23e42d7 182 Pfam PF03061 Thioesterase superfamily 25 96 3.7E-18 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 THSYN_RS12810 28e167f20f79cb05ee05d993b23e42d7 182 Gene3D G3DSA:3.10.129.10 2 155 1.8E-50 T 29-03-2018 THSYN_RS10990 0565e09a06cb0229f1599d1732c78307 414 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 28 409 54.374 T 29-03-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 THSYN_RS10990 0565e09a06cb0229f1599d1732c78307 414 PIRSF PIRSF001434 14 412 8.5E-128 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THSYN_RS10990 0565e09a06cb0229f1599d1732c78307 414 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 27 408 7.0E-171 T 29-03-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 THSYN_RS10990 0565e09a06cb0229f1599d1732c78307 414 Gene3D G3DSA:3.90.1150.10 277 412 1.1E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS10990 0565e09a06cb0229f1599d1732c78307 414 Gene3D G3DSA:3.40.640.10 25 276 3.6E-60 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS10990 0565e09a06cb0229f1599d1732c78307 414 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 28 408 7.6E-132 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THSYN_RS10990 0565e09a06cb0229f1599d1732c78307 414 SUPERFAMILY SSF53383 43 409 6.12E-115 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS10990 0565e09a06cb0229f1599d1732c78307 414 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 218 232 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THSYN_RS05575 d2e7848848a0e2023a004e365c772803 533 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 288 294 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS05575 d2e7848848a0e2023a004e365c772803 533 Gene3D G3DSA:3.40.50.150 179 478 2.0E-59 T 29-03-2018 THSYN_RS05575 d2e7848848a0e2023a004e365c772803 533 SUPERFAMILY SSF53335 19 523 8.36E-134 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS05575 d2e7848848a0e2023a004e365c772803 533 Pfam PF12161 HsdM N-terminal domain 19 133 6.9E-23 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS05575 d2e7848848a0e2023a004e365c772803 533 Pfam PF02384 N-6 DNA Methylase 157 485 3.1E-107 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS05575 d2e7848848a0e2023a004e365c772803 533 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 319 343 8.6E-21 T 29-03-2018 THSYN_RS05575 d2e7848848a0e2023a004e365c772803 533 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 285 297 8.6E-21 T 29-03-2018 THSYN_RS05575 d2e7848848a0e2023a004e365c772803 533 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 211 225 8.6E-21 T 29-03-2018 THSYN_RS05575 d2e7848848a0e2023a004e365c772803 533 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 181 197 8.6E-21 T 29-03-2018 THSYN_RS11985 fb232d5c769f235c9d2b82ad50c491f2 358 Gene3D G3DSA:3.40.50.2000 1 199 1.7E-10 T 29-03-2018 THSYN_RS11985 fb232d5c769f235c9d2b82ad50c491f2 358 Gene3D G3DSA:3.40.50.2000 200 341 5.1E-7 T 29-03-2018 THSYN_RS11985 fb232d5c769f235c9d2b82ad50c491f2 358 SUPERFAMILY SSF53756 1 332 1.19E-16 T 29-03-2018 THSYN_RS12845 a6a29720c18925e6bf43b4359c76e31e 147 SMART SM00387 51 145 4.9E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12845 a6a29720c18925e6bf43b4359c76e31e 147 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 53 142 1.3E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12845 a6a29720c18925e6bf43b4359c76e31e 147 PRINTS PR00344 Bacterial sensor protein C-terminal signature 105 123 2.0E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12845 a6a29720c18925e6bf43b4359c76e31e 147 PRINTS PR00344 Bacterial sensor protein C-terminal signature 129 142 2.0E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12845 a6a29720c18925e6bf43b4359c76e31e 147 PRINTS PR00344 Bacterial sensor protein C-terminal signature 87 101 2.0E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12845 a6a29720c18925e6bf43b4359c76e31e 147 SUPERFAMILY SSF55874 17 142 2.88E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12845 a6a29720c18925e6bf43b4359c76e31e 147 Gene3D G3DSA:3.30.565.10 10 147 5.1E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00210 0a2782d9e82b86d8854685271134fc52 429 Gene3D G3DSA:3.30.465.10 335 420 2.0E-14 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THSYN_RS00210 0a2782d9e82b86d8854685271134fc52 429 Pfam PF03471 Transporter associated domain 343 415 2.8E-11 T 29-03-2018 IPR005170 Transporter-associated domain THSYN_RS00210 0a2782d9e82b86d8854685271134fc52 429 SUPERFAMILY SSF56176 338 419 4.91E-18 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THSYN_RS00210 0a2782d9e82b86d8854685271134fc52 429 Pfam PF01595 Domain of unknown function DUF21 12 182 1.7E-48 T 29-03-2018 IPR002550 Domain of unknown function DUF21 THSYN_RS00210 0a2782d9e82b86d8854685271134fc52 429 SUPERFAMILY SSF54631 192 328 1.89E-26 T 29-03-2018 THSYN_RS00210 0a2782d9e82b86d8854685271134fc52 429 Pfam PF00571 CBS domain 279 325 0.0037 T 29-03-2018 IPR000644 CBS domain THSYN_RS00210 0a2782d9e82b86d8854685271134fc52 429 Gene3D G3DSA:3.10.580.10 185 334 1.1E-28 T 29-03-2018 THSYN_RS00210 0a2782d9e82b86d8854685271134fc52 429 SMART SM01091 340 417 3.6E-17 T 29-03-2018 IPR005170 Transporter-associated domain THSYN_RS29375 03e8a8f485d5c947679d0ca192029b28 84 Gene3D G3DSA:3.40.630.30 1 80 1.2E-4 T 29-03-2018 THSYN_RS29375 03e8a8f485d5c947679d0ca192029b28 84 SUPERFAMILY SSF55729 3 69 6.36E-5 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS17950 06b82dd26fa50ef2a574eb24ccb4d55d 204 SUPERFAMILY SSF52833 44 203 2.72E-50 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS17950 06b82dd26fa50ef2a574eb24ccb4d55d 204 Pfam PF02630 SCO1/SenC 47 184 2.1E-38 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THSYN_RS17950 06b82dd26fa50ef2a574eb24ccb4d55d 204 Gene3D G3DSA:3.40.30.10 39 202 2.2E-32 T 29-03-2018 THSYN_RS32650 5d21ea4257d11ddf10017dc2ab6c0eb0 383 SUPERFAMILY SSF102114 12 318 6.67E-73 T 29-03-2018 THSYN_RS32650 5d21ea4257d11ddf10017dc2ab6c0eb0 383 Gene3D G3DSA:3.20.20.70 11 315 9.1E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS32650 5d21ea4257d11ddf10017dc2ab6c0eb0 383 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 250 336 2.2E-8 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain THSYN_RS32650 5d21ea4257d11ddf10017dc2ab6c0eb0 383 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 380 183.014 T 29-03-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 THSYN_RS32650 5d21ea4257d11ddf10017dc2ab6c0eb0 383 PIRSF PIRSF037420 1 355 9.6E-120 T 29-03-2018 THSYN_RS32650 5d21ea4257d11ddf10017dc2ab6c0eb0 383 SMART SM00729 14 216 0.0049 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS32650 5d21ea4257d11ddf10017dc2ab6c0eb0 383 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 12 354 7.9E-165 T 29-03-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 THSYN_RS32650 5d21ea4257d11ddf10017dc2ab6c0eb0 383 Pfam PF13186 Iron-sulfur cluster-binding domain 243 309 5.2E-9 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain THSYN_RS32650 5d21ea4257d11ddf10017dc2ab6c0eb0 383 Pfam PF04055 Radical SAM superfamily 20 173 9.1E-23 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS32650 5d21ea4257d11ddf10017dc2ab6c0eb0 383 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 THSYN_RS29560 3d09d8da65514ffa13e4734473c996d4 80 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 4 69 8.6E-27 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS29560 3d09d8da65514ffa13e4734473c996d4 80 SUPERFAMILY SSF47598 5 44 7.89E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS29560 3d09d8da65514ffa13e4734473c996d4 80 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 1 79 1.9E-30 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS29560 3d09d8da65514ffa13e4734473c996d4 80 Gene3D G3DSA:1.10.1220.10 5 45 2.0E-10 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS30785 fcf6dd57e2308a77c39e46b81e8700e0 699 Pfam PF00271 Helicase conserved C-terminal domain 246 343 2.7E-19 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS30785 fcf6dd57e2308a77c39e46b81e8700e0 699 Gene3D G3DSA:3.40.50.300 230 373 1.8E-29 T 29-03-2018 THSYN_RS30785 fcf6dd57e2308a77c39e46b81e8700e0 699 Gene3D G3DSA:3.40.50.300 4 204 2.9E-35 T 29-03-2018 THSYN_RS30785 fcf6dd57e2308a77c39e46b81e8700e0 699 Pfam PF00270 DEAD/DEAH box helicase 28 196 2.0E-24 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS30785 fcf6dd57e2308a77c39e46b81e8700e0 699 SUPERFAMILY SSF52540 36 358 5.53E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30785 fcf6dd57e2308a77c39e46b81e8700e0 699 SMART SM00487 22 228 2.5E-29 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS30785 fcf6dd57e2308a77c39e46b81e8700e0 699 SMART SM00490 264 345 1.0E-20 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS31530 ef6225578435ca690813b062a557ed65 157 Pfam PF03729 Short repeat of unknown function (DUF308) 11 62 2.4E-6 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane THSYN_RS31530 ef6225578435ca690813b062a557ed65 157 Pfam PF03729 Short repeat of unknown function (DUF308) 50 118 1.7E-8 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 PIRSF PIRSF004557 2 443 4.5E-124 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 SUPERFAMILY SSF103491 4 427 2.75E-131 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 Gene3D G3DSA:1.10.3370.10 8 442 3.8E-160 T 29-03-2018 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 Pfam PF00344 SecY translocase 78 420 2.0E-116 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 8.2E-93 T 29-03-2018 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 25 43 8.2E-93 T 29-03-2018 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 405 423 8.2E-93 T 29-03-2018 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 373 391 8.2E-93 T 29-03-2018 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 8.2E-93 T 29-03-2018 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 318 340 8.2E-93 T 29-03-2018 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 77 97 8.2E-93 T 29-03-2018 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 118 141 8.2E-93 T 29-03-2018 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 275 294 8.2E-93 T 29-03-2018 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 22 432 8.3E-131 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 ProSitePatterns PS00755 Protein secY signature 1. 78 97 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THSYN_RS23815 25d47b0e6d416edb4d347d23137b4f76 450 Hamap MF_01465 Protein translocase subunit SecY [secY]. 12 436 29.359 T 29-03-2018 IPR026593 Protein translocase subunit SecY THSYN_RS19955 ac25225f965a77ddf5af0d2611349421 541 Gene3D G3DSA:1.10.10.10 213 317 1.9E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19955 ac25225f965a77ddf5af0d2611349421 541 Pfam PF03235 Protein of unknown function DUF262 23 224 6.0E-22 T 29-03-2018 IPR004919 Domain of unknown function DUF262 THSYN_RS15275 3507e5d2800cc1de08065cfe52a884a0 461 Pfam PF02321 Outer membrane efflux protein 274 455 1.9E-18 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THSYN_RS15275 3507e5d2800cc1de08065cfe52a884a0 461 Pfam PF02321 Outer membrane efflux protein 63 245 2.6E-25 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THSYN_RS15275 3507e5d2800cc1de08065cfe52a884a0 461 Gene3D G3DSA:1.20.1600.10 21 461 1.2E-84 T 29-03-2018 THSYN_RS15275 3507e5d2800cc1de08065cfe52a884a0 461 SUPERFAMILY SSF56954 9 460 6.41E-95 T 29-03-2018 THSYN_RS15275 3507e5d2800cc1de08065cfe52a884a0 461 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 13 457 6.6E-97 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 THSYN_RS10670 e8124452bcb9c58159b4cc3194eea40f 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 133 166 0.0018 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS10670 e8124452bcb9c58159b4cc3194eea40f 273 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 1 272 55.894 T 29-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 THSYN_RS10670 e8124452bcb9c58159b4cc3194eea40f 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 134 162 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 THSYN_RS10670 e8124452bcb9c58159b4cc3194eea40f 273 SUPERFAMILY SSF51161 2 256 1.66E-70 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS10670 e8124452bcb9c58159b4cc3194eea40f 273 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 175 209 1.8E-12 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS10670 e8124452bcb9c58159b4cc3194eea40f 273 Gene3D G3DSA:1.10.166.10 3 69 6.5E-25 T 29-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 THSYN_RS10670 e8124452bcb9c58159b4cc3194eea40f 273 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 5 273 5.6E-141 T 29-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 THSYN_RS10670 e8124452bcb9c58159b4cc3194eea40f 273 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 5 69 3.4E-23 T 29-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 THSYN_RS10670 e8124452bcb9c58159b4cc3194eea40f 273 Gene3D G3DSA:2.160.10.10 87 257 2.6E-34 T 29-03-2018 THSYN_RS14620 c8c598481437ee03a1c511323826fdf9 399 Gene3D G3DSA:2.30.42.10 307 396 1.0E-10 T 29-03-2018 THSYN_RS14620 c8c598481437ee03a1c511323826fdf9 399 SMART SM00228 309 381 2.7E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS14620 c8c598481437ee03a1c511323826fdf9 399 Pfam PF13180 PDZ domain 309 382 6.1E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS14620 c8c598481437ee03a1c511323826fdf9 399 SUPERFAMILY SSF50156 308 389 2.26E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS14705 b0b49bff30805af820fd1a58fac00d4d 231 SUPERFAMILY SSF52980 20 203 5.09E-11 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS14705 b0b49bff30805af820fd1a58fac00d4d 231 Gene3D G3DSA:1.10.287.950 15 173 4.9E-5 T 29-03-2018 THSYN_RS13940 ed54c1abc7b9859cc0cd13592e8bd6a5 301 Gene3D G3DSA:3.30.420.40 116 300 1.2E-53 T 29-03-2018 THSYN_RS13940 ed54c1abc7b9859cc0cd13592e8bd6a5 301 Pfam PF00480 ROK family 3 297 1.3E-73 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 THSYN_RS13940 ed54c1abc7b9859cc0cd13592e8bd6a5 301 Gene3D G3DSA:3.30.420.40 1 115 5.7E-25 T 29-03-2018 THSYN_RS13940 ed54c1abc7b9859cc0cd13592e8bd6a5 301 SUPERFAMILY SSF53067 2 297 1.37E-62 T 29-03-2018 THSYN_RS13940 ed54c1abc7b9859cc0cd13592e8bd6a5 301 ProSitePatterns PS01125 ROK family signature. 130 157 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 THSYN_RS23770 6affab56b5d3460f135e1784c36941cf 430 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 429 16.633 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 THSYN_RS23770 6affab56b5d3460f135e1784c36941cf 430 Gene3D G3DSA:3.40.50.2030 261 413 6.7E-56 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 THSYN_RS23770 6affab56b5d3460f135e1784c36941cf 430 Gene3D G3DSA:1.20.1270.20 1 130 4.9E-41 T 29-03-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 THSYN_RS23770 6affab56b5d3460f135e1784c36941cf 430 Gene3D G3DSA:3.40.50.2030 131 260 8.8E-53 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 THSYN_RS23770 6affab56b5d3460f135e1784c36941cf 430 SUPERFAMILY SSF56821 1 415 2.38E-140 T 29-03-2018 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 THSYN_RS23770 6affab56b5d3460f135e1784c36941cf 430 Pfam PF03063 Prismane/CO dehydrogenase family 77 416 1.0E-104 T 29-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 THSYN_RS23770 6affab56b5d3460f135e1784c36941cf 430 Pfam PF03063 Prismane/CO dehydrogenase family 1 83 3.9E-16 T 29-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 THSYN_RS23770 6affab56b5d3460f135e1784c36941cf 430 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 26 425 8.5E-164 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 THSYN_RS07990 a36d1b2c3d88a37df3495b46f27618d7 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 73 6.6E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS07990 a36d1b2c3d88a37df3495b46f27618d7 326 SUPERFAMILY SSF53850 102 306 2.88E-41 T 29-03-2018 THSYN_RS07990 a36d1b2c3d88a37df3495b46f27618d7 326 Gene3D G3DSA:3.40.190.10 189 274 3.3E-19 T 29-03-2018 THSYN_RS07990 a36d1b2c3d88a37df3495b46f27618d7 326 SUPERFAMILY SSF46785 13 121 4.89E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07990 a36d1b2c3d88a37df3495b46f27618d7 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 8.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS07990 a36d1b2c3d88a37df3495b46f27618d7 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 8.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS07990 a36d1b2c3d88a37df3495b46f27618d7 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 8.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS07990 a36d1b2c3d88a37df3495b46f27618d7 326 Pfam PF03466 LysR substrate binding domain 101 302 5.8E-40 T 29-03-2018 IPR005119 LysR, substrate-binding THSYN_RS07990 a36d1b2c3d88a37df3495b46f27618d7 326 Gene3D G3DSA:3.40.190.10 100 188 9.3E-22 T 29-03-2018 THSYN_RS07990 a36d1b2c3d88a37df3495b46f27618d7 326 Gene3D G3DSA:1.10.10.10 7 94 5.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 Gene3D G3DSA:2.40.50.140 131 186 1.2E-26 T 29-03-2018 THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 Gene3D G3DSA:2.30.30.30 4 63 2.6E-25 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 Pfam PF09285 Elongation factor P, C-terminal 131 186 3.6E-25 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 Pfam PF01132 Elongation factor P (EF-P) OB domain 71 123 7.1E-22 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 SUPERFAMILY SSF50249 130 187 9.08E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 SUPERFAMILY SSF50104 2 63 4.11E-20 T 29-03-2018 IPR008991 Translation protein SH3-like domain THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 PIRSF PIRSF005901 2 188 3.3E-68 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 TIGRFAM TIGR00038 efp: translation elongation factor P 4 187 3.1E-78 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 SMART SM01185 69 123 1.4E-24 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 SUPERFAMILY SSF50249 68 128 1.29E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 Gene3D G3DSA:2.40.50.140 67 129 1.0E-24 T 29-03-2018 THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 SMART SM00841 131 186 3.8E-32 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 Hamap MF_00141 Elongation factor P [efp]. 3 187 49.037 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site THSYN_RS13665 1d8663629fd160952eb479772d66e461 189 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 62 4.8E-27 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like THSYN_RS30640 5aa39c7131f31206606017d2b08c70d3 336 SUPERFAMILY SSF53850 32 325 2.61E-26 T 29-03-2018 THSYN_RS30640 5aa39c7131f31206606017d2b08c70d3 336 Pfam PF09084 NMT1/THI5 like 41 256 7.6E-29 T 29-03-2018 IPR015168 SsuA/THI5-like THSYN_RS30640 5aa39c7131f31206606017d2b08c70d3 336 Gene3D G3DSA:3.40.190.10 28 145 1.2E-9 T 29-03-2018 THSYN_RS30640 5aa39c7131f31206606017d2b08c70d3 336 Gene3D G3DSA:3.40.190.10 146 331 2.2E-15 T 29-03-2018 THSYN_RS24100 74c26c64c58416ca1c8ff945654576f6 456 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 452 6.3E-215 T 29-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 THSYN_RS24100 74c26c64c58416ca1c8ff945654576f6 456 Pfam PF02875 Mur ligase family, glutamate ligase domain 315 368 2.6E-9 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THSYN_RS24100 74c26c64c58416ca1c8ff945654576f6 456 Pfam PF08245 Mur ligase middle domain 108 295 1.5E-20 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS24100 74c26c64c58416ca1c8ff945654576f6 456 Gene3D G3DSA:3.40.50.720 1 90 4.5E-13 T 29-03-2018 THSYN_RS24100 74c26c64c58416ca1c8ff945654576f6 456 Pfam PF01225 Mur ligase family, catalytic domain 2 97 2.6E-16 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 THSYN_RS24100 74c26c64c58416ca1c8ff945654576f6 456 SUPERFAMILY SSF53244 314 452 3.92E-38 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THSYN_RS24100 74c26c64c58416ca1c8ff945654576f6 456 Gene3D G3DSA:3.90.190.20 318 456 4.6E-27 T 29-03-2018 THSYN_RS24100 74c26c64c58416ca1c8ff945654576f6 456 Gene3D G3DSA:3.40.1190.10 91 317 2.9E-41 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS24100 74c26c64c58416ca1c8ff945654576f6 456 SUPERFAMILY SSF51984 1 89 1.57E-22 T 29-03-2018 THSYN_RS24100 74c26c64c58416ca1c8ff945654576f6 456 SUPERFAMILY SSF53623 94 313 1.83E-51 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS24100 74c26c64c58416ca1c8ff945654576f6 456 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 453 60.889 T 29-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 THSYN_RS24285 a37a67831c77d4451688033c33cc0954 422 Pfam PF00072 Response regulator receiver domain 66 177 5.2E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS24285 a37a67831c77d4451688033c33cc0954 422 SUPERFAMILY SSF52172 66 203 7.26E-34 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS24285 a37a67831c77d4451688033c33cc0954 422 Gene3D G3DSA:3.40.50.2300 61 273 1.9E-32 T 29-03-2018 THSYN_RS24285 a37a67831c77d4451688033c33cc0954 422 Pfam PF07730 Histidine kinase 222 281 1.7E-8 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 THSYN_RS24285 a37a67831c77d4451688033c33cc0954 422 SMART SM00387 319 410 5.0E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS24285 a37a67831c77d4451688033c33cc0954 422 SUPERFAMILY SSF55874 288 408 1.57E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS24285 a37a67831c77d4451688033c33cc0954 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 329 408 2.2E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS24285 a37a67831c77d4451688033c33cc0954 422 Gene3D G3DSA:3.30.565.10 284 410 6.5E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS24285 a37a67831c77d4451688033c33cc0954 422 SMART SM00448 64 177 5.9E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS24285 a37a67831c77d4451688033c33cc0954 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 407 7.8E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS24285 a37a67831c77d4451688033c33cc0954 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 7.8E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS24285 a37a67831c77d4451688033c33cc0954 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 389 7.8E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS29065 5ebb82b0eb2de2be25b34b0ceeb3534b 453 Gene3D G3DSA:2.70.50.60 299 439 4.2E-17 T 29-03-2018 THSYN_RS29065 5ebb82b0eb2de2be25b34b0ceeb3534b 453 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS29065 5ebb82b0eb2de2be25b34b0ceeb3534b 453 SMART SM00382 53 233 8.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS29065 5ebb82b0eb2de2be25b34b0ceeb3534b 453 Gene3D G3DSA:3.40.50.300 5 273 3.1E-45 T 29-03-2018 THSYN_RS29065 5ebb82b0eb2de2be25b34b0ceeb3534b 453 SUPERFAMILY SSF52540 35 237 1.64E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29065 5ebb82b0eb2de2be25b34b0ceeb3534b 453 Pfam PF14524 Wzt C-terminal domain 312 440 1.1E-15 T 29-03-2018 IPR029439 Wzt, C-terminal THSYN_RS29065 5ebb82b0eb2de2be25b34b0ceeb3534b 453 Pfam PF00005 ABC transporter 44 176 9.1E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS23565 08505aa813e5cc65d8a7f30966e604b5 282 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 258 281 3.7E-6 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS23565 08505aa813e5cc65d8a7f30966e604b5 282 Gene3D G3DSA:2.60.120.200 104 251 1.1E-8 T 29-03-2018 THSYN_RS23565 08505aa813e5cc65d8a7f30966e604b5 282 SUPERFAMILY SSF49899 110 253 2.87E-8 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain THSYN_RS23565 08505aa813e5cc65d8a7f30966e604b5 282 Pfam PF07589 PEP-CTERM motif 257 279 4.9E-7 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS23825 99637c238f534bb9495c8bb11c48c451 71 Gene3D G3DSA:3.30.1390.20 11 65 6.0E-18 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain THSYN_RS23825 99637c238f534bb9495c8bb11c48c451 71 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 11 65 4.0E-20 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23825 99637c238f534bb9495c8bb11c48c451 71 SUPERFAMILY SSF55129 9 65 2.09E-17 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain THSYN_RS23825 99637c238f534bb9495c8bb11c48c451 71 PIRSF PIRSF002211 5 67 2.8E-24 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23825 99637c238f534bb9495c8bb11c48c451 71 Pfam PF00327 Ribosomal protein L30p/L7e 12 61 1.4E-13 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain THSYN_RS23825 99637c238f534bb9495c8bb11c48c451 71 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 7 65 17.907 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS30835 9e36fdbb5658c1079288837b019b0a3e 825 SUPERFAMILY SSF53335 63 325 2.07E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS30835 9e36fdbb5658c1079288837b019b0a3e 825 SUPERFAMILY SSF53335 360 483 2.07E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS30835 9e36fdbb5658c1079288837b019b0a3e 825 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 371 377 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS30835 9e36fdbb5658c1079288837b019b0a3e 825 Gene3D G3DSA:3.40.50.150 203 557 1.3E-27 T 29-03-2018 THSYN_RS30835 9e36fdbb5658c1079288837b019b0a3e 825 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 235 249 1.7E-5 T 29-03-2018 THSYN_RS30835 9e36fdbb5658c1079288837b019b0a3e 825 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 368 380 1.7E-5 T 29-03-2018 THSYN_RS30835 9e36fdbb5658c1079288837b019b0a3e 825 Gene3D G3DSA:3.90.220.10 558 776 1.6E-16 T 29-03-2018 THSYN_RS08225 5362ce6f36c651d4bf122d54f55c44c0 158 Gene3D G3DSA:2.60.120.10 20 146 1.3E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS08225 5362ce6f36c651d4bf122d54f55c44c0 158 SMART SM00100 5 127 0.003 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS08225 5362ce6f36c651d4bf122d54f55c44c0 158 SUPERFAMILY SSF51206 24 126 2.88E-18 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like THSYN_RS08225 5362ce6f36c651d4bf122d54f55c44c0 158 Pfam PF00027 Cyclic nucleotide-binding domain 24 108 1.5E-15 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS28305 19a5d981c1420d04850d3116caddb02e 576 Pfam PF00374 Nickel-dependent hydrogenase 39 561 9.3E-233 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THSYN_RS28305 19a5d981c1420d04850d3116caddb02e 576 SUPERFAMILY SSF56762 1 561 3.66E-174 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS28305 19a5d981c1420d04850d3116caddb02e 576 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 552 561 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THSYN_RS28305 19a5d981c1420d04850d3116caddb02e 576 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 39 64 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THSYN_RS28305 19a5d981c1420d04850d3116caddb02e 576 Gene3D G3DSA:1.10.645.10 1 561 4.1E-199 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS25155 db3cf89535f66b29f1b79c8ffafbc978 313 Pfam PF13439 Glycosyltransferase Family 4 8 94 1.4E-7 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS25155 db3cf89535f66b29f1b79c8ffafbc978 313 SUPERFAMILY SSF53756 12 312 1.26E-48 T 29-03-2018 THSYN_RS25155 db3cf89535f66b29f1b79c8ffafbc978 313 Gene3D G3DSA:3.40.50.2000 3 122 2.8E-6 T 29-03-2018 THSYN_RS25155 db3cf89535f66b29f1b79c8ffafbc978 313 Pfam PF00534 Glycosyl transferases group 1 134 277 3.2E-24 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS25155 db3cf89535f66b29f1b79c8ffafbc978 313 Gene3D G3DSA:3.40.50.2000 123 291 4.4E-27 T 29-03-2018 THSYN_RS25955 8319411328b8bb56ac661f8f7b5f54a0 101 Gene3D G3DSA:3.30.70.100 10 101 2.0E-23 T 29-03-2018 THSYN_RS25955 8319411328b8bb56ac661f8f7b5f54a0 101 ProSitePatterns PS00150 Acylphosphatase signature 1. 21 31 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THSYN_RS25955 8319411328b8bb56ac661f8f7b5f54a0 101 SUPERFAMILY SSF54975 15 100 1.18E-25 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THSYN_RS25955 8319411328b8bb56ac661f8f7b5f54a0 101 Pfam PF00708 Acylphosphatase 18 99 1.5E-22 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THSYN_RS25955 8319411328b8bb56ac661f8f7b5f54a0 101 ProSitePatterns PS00151 Acylphosphatase signature 2. 45 61 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THSYN_RS23840 da218a91da54e8a54bf1025eb1662d4e 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 2.9E-33 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THSYN_RS23840 da218a91da54e8a54bf1025eb1662d4e 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 2.9E-33 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THSYN_RS23840 da218a91da54e8a54bf1025eb1662d4e 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 2.9E-33 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THSYN_RS23840 da218a91da54e8a54bf1025eb1662d4e 177 Pfam PF00347 Ribosomal protein L6 90 164 1.2E-20 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23840 da218a91da54e8a54bf1025eb1662d4e 177 Pfam PF00347 Ribosomal protein L6 11 81 1.3E-14 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23840 da218a91da54e8a54bf1025eb1662d4e 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23840 da218a91da54e8a54bf1025eb1662d4e 177 SUPERFAMILY SSF56053 1 82 1.34E-21 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23840 da218a91da54e8a54bf1025eb1662d4e 177 PIRSF PIRSF002162 1 177 2.9E-40 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23840 da218a91da54e8a54bf1025eb1662d4e 177 SUPERFAMILY SSF56053 83 177 1.21E-34 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23840 da218a91da54e8a54bf1025eb1662d4e 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 9.2E-72 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THSYN_RS23840 da218a91da54e8a54bf1025eb1662d4e 177 Gene3D G3DSA:3.90.930.12 2 82 2.0E-23 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23840 da218a91da54e8a54bf1025eb1662d4e 177 Gene3D G3DSA:3.90.930.12 83 177 1.5E-37 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23840 da218a91da54e8a54bf1025eb1662d4e 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.309 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THSYN_RS32445 50e06a4757810d3b422f5e49fcf2d2dd 84 Pfam PF07704 Rv0623-like transcription factor 1 83 3.8E-20 T 29-03-2018 IPR011660 Antitoxin VapB-like THSYN_RS23640 70f8e91a42989ba19a6ebf191caf13b6 405 Pfam PF00534 Glycosyl transferases group 1 229 365 1.7E-29 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS23640 70f8e91a42989ba19a6ebf191caf13b6 405 Pfam PF13439 Glycosyltransferase Family 4 75 211 1.0E-12 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS23640 70f8e91a42989ba19a6ebf191caf13b6 405 Gene3D G3DSA:3.40.50.2000 221 384 1.0E-41 T 29-03-2018 THSYN_RS23640 70f8e91a42989ba19a6ebf191caf13b6 405 Gene3D G3DSA:3.40.50.2000 34 220 6.8E-10 T 29-03-2018 THSYN_RS23640 70f8e91a42989ba19a6ebf191caf13b6 405 SUPERFAMILY SSF53756 31 399 3.56E-68 T 29-03-2018 THSYN_RS07445 cb89393cf71a0b1538d64436eef57773 84 Pfam PF14076 Domain of unknown function (DUF4258) 12 78 5.9E-13 T 29-03-2018 IPR025354 Protein of unknown function DUF4258 THSYN_RS19720 65fb0c2c052e6d05e9c9fddb86f68d12 296 Gene3D G3DSA:1.25.40.10 38 287 4.2E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19720 65fb0c2c052e6d05e9c9fddb86f68d12 296 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 165 283 4.0E-32 T 29-03-2018 IPR014162 Cell division coordinator CpoB, C-terminal THSYN_RS19720 65fb0c2c052e6d05e9c9fddb86f68d12 296 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 3 286 18.933 T 29-03-2018 IPR034706 Cell division coordinator CpoB GO:0051301 THSYN_RS19720 65fb0c2c052e6d05e9c9fddb86f68d12 296 Pfam PF16331 TolA binding protein trimerisation 29 96 1.3E-18 T 29-03-2018 IPR032519 YbgF, trimerisation domain GO:0070206 THSYN_RS19720 65fb0c2c052e6d05e9c9fddb86f68d12 296 Pfam PF13525 Outer membrane lipoprotein 166 286 5.4E-14 T 29-03-2018 THSYN_RS19720 65fb0c2c052e6d05e9c9fddb86f68d12 296 SUPERFAMILY SSF48452 170 283 3.35E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS02950 2d136fa75c6c807096605debe6095c14 540 Gene3D G3DSA:3.40.50.280 22 142 1.8E-17 T 29-03-2018 THSYN_RS02950 2d136fa75c6c807096605debe6095c14 540 Gene3D G3DSA:3.80.30.20 198 407 2.5E-31 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe THSYN_RS02950 2d136fa75c6c807096605debe6095c14 540 Pfam PF04055 Radical SAM superfamily 204 366 2.5E-19 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS02950 2d136fa75c6c807096605debe6095c14 540 SMART SM00729 200 402 6.5E-24 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS02950 2d136fa75c6c807096605debe6095c14 540 Pfam PF02310 B12 binding domain 24 139 3.3E-21 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 THSYN_RS02950 2d136fa75c6c807096605debe6095c14 540 SUPERFAMILY SSF52242 30 141 2.51E-5 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 THSYN_RS02950 2d136fa75c6c807096605debe6095c14 540 SUPERFAMILY SSF102114 162 394 1.96E-40 T 29-03-2018 THSYN_RS23890 a03ed5879f3452e72e025c5bc0913641 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23890 a03ed5879f3452e72e025c5bc0913641 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 28.138 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23890 a03ed5879f3452e72e025c5bc0913641 110 Gene3D G3DSA:3.90.470.10 1 110 3.2E-44 T 29-03-2018 THSYN_RS23890 a03ed5879f3452e72e025c5bc0913641 110 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 1.4E-38 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 THSYN_RS23890 a03ed5879f3452e72e025c5bc0913641 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.4E-45 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23890 a03ed5879f3452e72e025c5bc0913641 110 SUPERFAMILY SSF54843 2 109 5.89E-43 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 THSYN_RS29270 0d643143c28c42a067a31fb53af7a9a8 666 SMART SM00460 406 477 7.2E-21 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS29270 0d643143c28c42a067a31fb53af7a9a8 666 Pfam PF11992 Domain of unknown function (DUF3488) 19 331 2.7E-86 T 29-03-2018 IPR021878 Protein of unknown function DUF3488 THSYN_RS29270 0d643143c28c42a067a31fb53af7a9a8 666 Gene3D G3DSA:3.90.260.10 393 489 8.6E-16 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS29270 0d643143c28c42a067a31fb53af7a9a8 666 SUPERFAMILY SSF54001 281 604 3.22E-49 T 29-03-2018 THSYN_RS29270 0d643143c28c42a067a31fb53af7a9a8 666 Pfam PF13559 Domain of unknown function (DUF4129) 589 648 1.3E-7 T 29-03-2018 IPR025403 Domain of unknown function DUF4129 THSYN_RS29270 0d643143c28c42a067a31fb53af7a9a8 666 Pfam PF01841 Transglutaminase-like superfamily 380 475 1.2E-19 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS29340 c57147cb297163ebd56e83a4ff08bbe0 934 Pfam PF11369 Protein of unknown function (DUF3160) 606 918 5.5E-40 T 29-03-2018 IPR022601 Protein of unknown function DUF3160 THSYN_RS29340 c57147cb297163ebd56e83a4ff08bbe0 934 Pfam PF11369 Protein of unknown function (DUF3160) 372 517 1.3E-8 T 29-03-2018 IPR022601 Protein of unknown function DUF3160 THSYN_RS29340 c57147cb297163ebd56e83a4ff08bbe0 934 Gene3D G3DSA:2.130.10.10 30 465 4.2E-7 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS29340 c57147cb297163ebd56e83a4ff08bbe0 934 SMART SM01325 350 919 1.2E-36 T 29-03-2018 IPR022601 Protein of unknown function DUF3160 THSYN_RS29340 c57147cb297163ebd56e83a4ff08bbe0 934 SUPERFAMILY SSF82171 48 131 1.88E-7 T 29-03-2018 THSYN_RS29340 c57147cb297163ebd56e83a4ff08bbe0 934 SUPERFAMILY SSF82171 226 329 1.88E-7 T 29-03-2018 THSYN_RS32250 5ae776b7a97454720295829f1cae1b7a 107 Gene3D G3DSA:1.10.1200.10 1 106 6.5E-7 T 29-03-2018 THSYN_RS32250 5ae776b7a97454720295829f1cae1b7a 107 Pfam PF07377 Protein of unknown function (DUF1493) 13 104 5.8E-14 T 29-03-2018 IPR010862 Protein of unknown function DUF1493 THSYN_RS32250 5ae776b7a97454720295829f1cae1b7a 107 SUPERFAMILY SSF47336 12 64 3.93E-5 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain THSYN_RS14450 fde2a6b595c9f5e60963e3a373d2d2be 135 ProSitePatterns PS00018 EF-hand calcium-binding domain. 42 54 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS14450 fde2a6b595c9f5e60963e3a373d2d2be 135 Gene3D G3DSA:1.10.238.10 12 50 0.0025 T 29-03-2018 THSYN_RS14450 fde2a6b595c9f5e60963e3a373d2d2be 135 Pfam PF13202 EF hand 38 56 1.3E-5 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS14450 fde2a6b595c9f5e60963e3a373d2d2be 135 Pfam PF13202 EF hand 81 97 0.035 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS14450 fde2a6b595c9f5e60963e3a373d2d2be 135 ProSitePatterns PS00018 EF-hand calcium-binding domain. 85 97 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS14450 fde2a6b595c9f5e60963e3a373d2d2be 135 Gene3D G3DSA:1.10.238.10 51 85 3.2E-8 T 29-03-2018 THSYN_RS14450 fde2a6b595c9f5e60963e3a373d2d2be 135 Gene3D G3DSA:1.10.238.10 86 109 0.0081 T 29-03-2018 THSYN_RS14450 fde2a6b595c9f5e60963e3a373d2d2be 135 SUPERFAMILY SSF47473 37 99 2.04E-7 T 29-03-2018 IPR011992 EF-hand domain pair THSYN_RS25925 e731519e86a9fe8201da5d0e6397ea41 170 SUPERFAMILY SSF54637 3 168 5.22E-55 T 29-03-2018 IPR029069 HotDog domain THSYN_RS25925 e731519e86a9fe8201da5d0e6397ea41 170 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 3 169 4.0E-88 T 29-03-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THSYN_RS25925 e731519e86a9fe8201da5d0e6397ea41 170 Pfam PF07977 FabA-like domain 27 157 1.8E-47 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THSYN_RS25925 e731519e86a9fe8201da5d0e6397ea41 170 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 1 170 48.676 T 29-03-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THSYN_RS25925 e731519e86a9fe8201da5d0e6397ea41 170 Gene3D G3DSA:3.10.129.10 1 170 1.9E-47 T 29-03-2018 THSYN_RS11880 e4d6caef8cf71da9c9cf0f70d16d3074 126 Pfam PF00741 Gas vesicle protein 16 54 1.5E-17 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 THSYN_RS11880 e4d6caef8cf71da9c9cf0f70d16d3074 126 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 17 31 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 SUPERFAMILY SSF52540 452 686 9.96E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 ProSitePatterns PS00674 AAA-protein family signature. 596 614 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 Gene3D G3DSA:2.40.40.20 3 89 2.2E-20 T 29-03-2018 THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 90 1.0E-21 T 29-03-2018 IPR003338 CDC48, N-terminal subdomain THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 SMART SM01073 8 92 2.9E-26 T 29-03-2018 IPR003338 CDC48, N-terminal subdomain THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 112 166 9.1E-9 T 29-03-2018 IPR004201 CDC48, domain 2 THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 ProSitePatterns PS00674 AAA-protein family signature. 321 339 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 SUPERFAMILY SSF50692 3 89 2.49E-23 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 Gene3D G3DSA:3.40.50.300 166 358 2.2E-58 T 29-03-2018 THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 Gene3D G3DSA:3.40.50.300 444 633 9.8E-63 T 29-03-2018 THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 Gene3D G3DSA:3.10.330.10 91 165 3.2E-15 T 29-03-2018 IPR029067 CDC48 domain 2-like THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 SUPERFAMILY SSF52540 180 442 3.38E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 SMART SM01072 105 170 4.4E-7 T 29-03-2018 IPR004201 CDC48, domain 2 THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 Gene3D G3DSA:1.10.8.60 359 443 1.7E-26 T 29-03-2018 THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 689 5.3E-267 T 29-03-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 SUPERFAMILY SSF54585 94 186 1.34E-11 T 29-03-2018 IPR029067 CDC48 domain 2-like THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 SMART SM00382 217 353 1.7E-21 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 SMART SM00382 490 628 9.5E-22 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 Gene3D G3DSA:1.10.8.60 634 713 1.1E-19 T 29-03-2018 THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 494 626 1.4E-45 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS11865 e276942f397d2f59fca72d1bef8398a3 713 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 221 350 5.4E-45 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS00710 77478b58f44bb47dfd41e42c8edc839c 439 Gene3D G3DSA:3.30.450.20 212 276 3.0E-11 T 29-03-2018 THSYN_RS00710 77478b58f44bb47dfd41e42c8edc839c 439 Pfam PF00990 Diguanylate cyclase, GGDEF domain 264 427 1.5E-35 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS00710 77478b58f44bb47dfd41e42c8edc839c 439 SUPERFAMILY SSF55785 213 266 1.34E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS00710 77478b58f44bb47dfd41e42c8edc839c 439 SUPERFAMILY SSF55073 264 432 1.18E-40 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS00710 77478b58f44bb47dfd41e42c8edc839c 439 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 223 264 2.4E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS00710 77478b58f44bb47dfd41e42c8edc839c 439 SMART SM00091 223 291 8.2E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS00710 77478b58f44bb47dfd41e42c8edc839c 439 SMART SM00267 257 431 1.4E-37 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS00710 77478b58f44bb47dfd41e42c8edc839c 439 Pfam PF13188 PAS domain 224 265 1.1E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS00710 77478b58f44bb47dfd41e42c8edc839c 439 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 264 430 6.3E-35 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS00710 77478b58f44bb47dfd41e42c8edc839c 439 Gene3D G3DSA:3.30.70.270 277 439 2.9E-46 T 29-03-2018 THSYN_RS19360 ab98100ccbc82940e9511034c6e6f338 299 SUPERFAMILY SSF55874 221 291 2.26E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS19360 ab98100ccbc82940e9511034c6e6f338 299 SUPERFAMILY SSF55874 168 193 2.26E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS19360 ab98100ccbc82940e9511034c6e6f338 299 Gene3D G3DSA:3.30.565.10 130 297 6.7E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS19360 ab98100ccbc82940e9511034c6e6f338 299 Pfam PF13581 Histidine kinase-like ATPase domain 162 293 2.4E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS19360 ab98100ccbc82940e9511034c6e6f338 299 SMART SM00448 4 119 9.7E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS19360 ab98100ccbc82940e9511034c6e6f338 299 Gene3D G3DSA:3.40.50.2300 1 129 2.0E-34 T 29-03-2018 THSYN_RS19360 ab98100ccbc82940e9511034c6e6f338 299 SUPERFAMILY SSF52172 1 144 5.98E-37 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS19360 ab98100ccbc82940e9511034c6e6f338 299 Pfam PF00072 Response regulator receiver domain 6 118 1.1E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS22730 27931b6f5b46cd9a4a7fae34f6bdbacb 581 SMART SM00226 432 575 1.3E-26 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS22730 27931b6f5b46cd9a4a7fae34f6bdbacb 581 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 505 520 5.4E-10 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS22730 27931b6f5b46cd9a4a7fae34f6bdbacb 581 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 434 451 5.4E-10 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS22730 27931b6f5b46cd9a4a7fae34f6bdbacb 581 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 471 487 5.4E-10 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS22730 27931b6f5b46cd9a4a7fae34f6bdbacb 581 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 547 562 5.4E-10 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS22730 27931b6f5b46cd9a4a7fae34f6bdbacb 581 Gene3D G3DSA:3.40.50.2300 432 579 9.4E-32 T 29-03-2018 THSYN_RS22730 27931b6f5b46cd9a4a7fae34f6bdbacb 581 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 435 572 4.3E-21 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS22730 27931b6f5b46cd9a4a7fae34f6bdbacb 581 Gene3D G3DSA:3.40.50.20 5 120 6.4E-4 T 29-03-2018 THSYN_RS22730 27931b6f5b46cd9a4a7fae34f6bdbacb 581 SUPERFAMILY SSF56059 107 324 2.83E-31 T 29-03-2018 THSYN_RS22730 27931b6f5b46cd9a4a7fae34f6bdbacb 581 SUPERFAMILY SSF52788 433 575 4.84E-31 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS22730 27931b6f5b46cd9a4a7fae34f6bdbacb 581 Gene3D G3DSA:3.30.1490.20 121 194 1.1E-13 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS22730 27931b6f5b46cd9a4a7fae34f6bdbacb 581 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 302 1.8E-10 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THSYN_RS22730 27931b6f5b46cd9a4a7fae34f6bdbacb 581 Gene3D G3DSA:3.30.470.20 195 326 1.4E-12 T 29-03-2018 THSYN_RS27650 8ea75289db277c407b2a08754b682c04 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 202 315 3.8E-29 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 THSYN_RS27650 8ea75289db277c407b2a08754b682c04 317 Gene3D G3DSA:3.40.50.2020 153 309 1.5E-38 T 29-03-2018 THSYN_RS27650 8ea75289db277c407b2a08754b682c04 317 SUPERFAMILY SSF53271 71 307 7.61E-63 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like THSYN_RS27650 8ea75289db277c407b2a08754b682c04 317 SMART SM01400 6 123 8.3E-75 T 29-03-2018 THSYN_RS27650 8ea75289db277c407b2a08754b682c04 317 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 131 146 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 THSYN_RS27650 8ea75289db277c407b2a08754b682c04 317 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 6 316 49.047 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 THSYN_RS27650 8ea75289db277c407b2a08754b682c04 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 6 315 1.8E-117 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 THSYN_RS27650 8ea75289db277c407b2a08754b682c04 317 Gene3D G3DSA:3.40.50.2020 3 152 8.6E-65 T 29-03-2018 THSYN_RS27650 8ea75289db277c407b2a08754b682c04 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 123 2.1E-46 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 THSYN_RS25935 30d215f1d38930ac87e200043333c2ec 99 Gene3D G3DSA:3.30.2310.20 2 94 2.3E-4 T 29-03-2018 THSYN_RS25935 30d215f1d38930ac87e200043333c2ec 99 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 94 2.3E-12 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS25485 ab4404878b0214e2bae2eac3b9b4f9ee 447 Pfam PF01593 Flavin containing amine oxidoreductase 13 278 2.2E-20 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THSYN_RS25485 ab4404878b0214e2bae2eac3b9b4f9ee 447 Gene3D G3DSA:3.90.660.20 44 330 5.6E-30 T 29-03-2018 THSYN_RS25485 ab4404878b0214e2bae2eac3b9b4f9ee 447 SUPERFAMILY SSF51905 385 416 1.73E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS25485 ab4404878b0214e2bae2eac3b9b4f9ee 447 SUPERFAMILY SSF51905 6 303 1.73E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS25485 ab4404878b0214e2bae2eac3b9b4f9ee 447 Gene3D G3DSA:3.50.50.60 2 43 0.012 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS16015 abe94033d875ecf8edae439c903ca588 168 SMART SM00953 27 152 2.8E-10 T 29-03-2018 IPR014914 RES domain THSYN_RS16015 abe94033d875ecf8edae439c903ca588 168 Pfam PF08808 RES domain 15 142 1.3E-21 T 29-03-2018 IPR014914 RES domain THSYN_RS20890 67bcfcdefc0ed3fba519d4a984845d29 131 SMART SM00448 3 116 1.4E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS20890 67bcfcdefc0ed3fba519d4a984845d29 131 SUPERFAMILY SSF52172 2 122 3.56E-38 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS20890 67bcfcdefc0ed3fba519d4a984845d29 131 Pfam PF00072 Response regulator receiver domain 5 116 1.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS20890 67bcfcdefc0ed3fba519d4a984845d29 131 Gene3D G3DSA:3.40.50.2300 1 130 3.6E-38 T 29-03-2018 THSYN_RS03645 294783d06e38ec8cad1ec157b32b4d60 899 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 597 608 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site THSYN_RS03645 294783d06e38ec8cad1ec157b32b4d60 899 Pfam PF00082 Subtilase family 592 853 8.9E-24 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS03645 294783d06e38ec8cad1ec157b32b4d60 899 Gene3D G3DSA:3.40.50.200 537 898 5.6E-50 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS03645 294783d06e38ec8cad1ec157b32b4d60 899 SUPERFAMILY SSF52743 757 878 4.84E-49 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS03645 294783d06e38ec8cad1ec157b32b4d60 899 SUPERFAMILY SSF52743 578 698 4.84E-49 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS03645 294783d06e38ec8cad1ec157b32b4d60 899 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 634 644 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site THSYN_RS03645 294783d06e38ec8cad1ec157b32b4d60 899 Pfam PF13191 AAA ATPase domain 27 189 1.8E-8 T 29-03-2018 THSYN_RS03645 294783d06e38ec8cad1ec157b32b4d60 899 Gene3D G3DSA:3.40.50.300 17 457 8.7E-9 T 29-03-2018 THSYN_RS03645 294783d06e38ec8cad1ec157b32b4d60 899 PRINTS PR00723 Subtilisin serine protease family (S8) signature 630 643 3.7E-17 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS03645 294783d06e38ec8cad1ec157b32b4d60 899 PRINTS PR00723 Subtilisin serine protease family (S8) signature 835 851 3.7E-17 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS03645 294783d06e38ec8cad1ec157b32b4d60 899 PRINTS PR00723 Subtilisin serine protease family (S8) signature 592 611 3.7E-17 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS03645 294783d06e38ec8cad1ec157b32b4d60 899 SUPERFAMILY SSF52540 155 239 8.62E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03645 294783d06e38ec8cad1ec157b32b4d60 899 SUPERFAMILY SSF52540 25 116 8.62E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13045 a58e277719768d7cfb2b7bad3dff709f 343 SUPERFAMILY SSF81345 8 335 6.15E-69 T 29-03-2018 IPR029022 ABC transporter, BtuC-like THSYN_RS13045 a58e277719768d7cfb2b7bad3dff709f 343 Pfam PF01032 FecCD transport family 21 335 2.0E-76 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 THSYN_RS13045 a58e277719768d7cfb2b7bad3dff709f 343 Gene3D G3DSA:1.10.3470.10 5 342 4.1E-63 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like THSYN_RS20790 0b875453d4315cadddfcd4025e2cf4fc 319 Gene3D G3DSA:1.10.3430.10 14 318 7.1E-54 T 29-03-2018 THSYN_RS20790 0b875453d4315cadddfcd4025e2cf4fc 319 Pfam PF03253 Urea transporter 21 293 4.0E-39 T 29-03-2018 IPR004937 Urea transporter GO:0015204|GO:0016021|GO:0071918 Reactome: R-HSA-425366 THSYN_RS10885 156cc09689bcd899bd2141bdfd94507e 210 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 195 1.0E-77 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 THSYN_RS10885 156cc09689bcd899bd2141bdfd94507e 210 Gene3D G3DSA:3.20.19.10 1 183 1.6E-47 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THSYN_RS10885 156cc09689bcd899bd2141bdfd94507e 210 SUPERFAMILY SSF52016 1 202 2.35E-60 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THSYN_RS10885 156cc09689bcd899bd2141bdfd94507e 210 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 209 41.574 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 THSYN_RS10885 156cc09689bcd899bd2141bdfd94507e 210 Pfam PF00694 Aconitase C-terminal domain 2 131 1.6E-33 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS16095 81699be5f1901fad94ff0b586791f5bc 217 Gene3D G3DSA:3.40.50.300 1 217 9.7E-28 T 29-03-2018 THSYN_RS16095 81699be5f1901fad94ff0b586791f5bc 217 SUPERFAMILY SSF52540 36 214 9.48E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16095 81699be5f1901fad94ff0b586791f5bc 217 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 38 209 2.3E-6 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THSYN_RS26935 eda803b2a5aba9ea28ca2e16f4a8e03a 316 Gene3D G3DSA:3.30.70.1350 223 296 2.6E-9 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain THSYN_RS26935 eda803b2a5aba9ea28ca2e16f4a8e03a 316 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 24 294 2.5E-72 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THSYN_RS26935 eda803b2a5aba9ea28ca2e16f4a8e03a 316 SUPERFAMILY SSF161111 23 216 4.58E-50 T 29-03-2018 THSYN_RS26935 eda803b2a5aba9ea28ca2e16f4a8e03a 316 Pfam PF01545 Cation efflux family 25 215 1.0E-42 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THSYN_RS26935 eda803b2a5aba9ea28ca2e16f4a8e03a 316 Gene3D G3DSA:1.20.1510.10 23 215 3.5E-51 T 29-03-2018 THSYN_RS26935 eda803b2a5aba9ea28ca2e16f4a8e03a 316 SUPERFAMILY SSF160240 230 294 1.96E-6 T 29-03-2018 THSYN_RS02920 beaf0de29af0d7c148a413c25085a01e 241 Pfam PF00005 ABC transporter 19 153 3.2E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS02920 beaf0de29af0d7c148a413c25085a01e 241 SUPERFAMILY SSF52540 2 215 1.95E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02920 beaf0de29af0d7c148a413c25085a01e 241 SMART SM00382 28 201 1.3E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS02920 beaf0de29af0d7c148a413c25085a01e 241 Gene3D G3DSA:3.40.50.300 1 238 6.1E-55 T 29-03-2018 THSYN_RS18340 1473ef2812867b951a04d301da3b647b 479 SUPERFAMILY SSF102114 43 382 3.14E-40 T 29-03-2018 THSYN_RS18340 1473ef2812867b951a04d301da3b647b 479 Gene3D G3DSA:3.20.20.70 38 394 4.4E-32 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS18340 1473ef2812867b951a04d301da3b647b 479 TIGRFAM TIGR03942 sulfatase_rSAM: anaerobic sulfatase maturase 34 420 2.9E-140 T 29-03-2018 IPR023867 Anaerobic sulphatase maturase, radical SAM GO:0016491 THSYN_RS18340 1473ef2812867b951a04d301da3b647b 479 Pfam PF13394 4Fe-4S single cluster domain 42 133 7.4E-5 T 29-03-2018 THSYN_RS18340 1473ef2812867b951a04d301da3b647b 479 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 317 401 2.1E-19 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain THSYN_RS18340 1473ef2812867b951a04d301da3b647b 479 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 188 435 1.0E-14 T 29-03-2018 THSYN_RS18340 1473ef2812867b951a04d301da3b647b 479 SUPERFAMILY SSF103642 443 462 1.16E-5 T 29-03-2018 THSYN_RS18340 1473ef2812867b951a04d301da3b647b 479 Pfam PF02810 SEC-C motif 447 461 3.2E-4 T 29-03-2018 IPR004027 SEC-C motif THSYN_RS18340 1473ef2812867b951a04d301da3b647b 479 Pfam PF04055 Radical SAM superfamily 42 188 1.6E-9 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS18340 1473ef2812867b951a04d301da3b647b 479 Pfam PF13186 Iron-sulfur cluster-binding domain 317 373 4.5E-9 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain THSYN_RS18340 1473ef2812867b951a04d301da3b647b 479 Gene3D G3DSA:3.10.450.50 436 464 1.0E-4 T 29-03-2018 THSYN_RS12575 76741e3919af90df5f0fd7526d08b3bb 384 Gene3D G3DSA:3.30.870.10 6 165 9.6E-22 T 29-03-2018 THSYN_RS12575 76741e3919af90df5f0fd7526d08b3bb 384 SUPERFAMILY SSF56024 6 162 9.87E-26 T 29-03-2018 THSYN_RS12575 76741e3919af90df5f0fd7526d08b3bb 384 SUPERFAMILY SSF56024 192 353 3.81E-20 T 29-03-2018 THSYN_RS12575 76741e3919af90df5f0fd7526d08b3bb 384 Gene3D G3DSA:3.30.870.10 208 361 1.3E-17 T 29-03-2018 THSYN_RS12575 76741e3919af90df5f0fd7526d08b3bb 384 Pfam PF13091 PLD-like domain 23 153 2.7E-12 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THSYN_RS12575 76741e3919af90df5f0fd7526d08b3bb 384 Pfam PF13091 PLD-like domain 224 348 6.7E-17 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THSYN_RS27030 aca2d21a6a6c14d94d7260d8aec235aa 106 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 96 3.7E-17 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS27030 aca2d21a6a6c14d94d7260d8aec235aa 106 Gene3D G3DSA:3.30.2310.20 1 98 8.4E-13 T 29-03-2018 THSYN_RS27030 aca2d21a6a6c14d94d7260d8aec235aa 106 SUPERFAMILY SSF143011 1 96 1.02E-7 T 29-03-2018 IPR035095 Toxin RelE-like domain THSYN_RS12705 6fc29ae0258955855da4ddc3597fdd3f 363 Pfam PF13406 Transglycosylase SLT domain 54 345 2.6E-90 T 29-03-2018 IPR031304 Transglycosylase SLT domain 2 THSYN_RS12705 6fc29ae0258955855da4ddc3597fdd3f 363 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 54 348 3.2E-105 T 29-03-2018 IPR011757 Lytic transglycosylase MltB THSYN_RS12705 6fc29ae0258955855da4ddc3597fdd3f 363 Gene3D G3DSA:1.10.530.10 231 353 1.8E-30 T 29-03-2018 THSYN_RS12705 6fc29ae0258955855da4ddc3597fdd3f 363 SUPERFAMILY SSF53955 45 350 4.64E-86 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS12705 6fc29ae0258955855da4ddc3597fdd3f 363 Gene3D G3DSA:1.10.8.350 44 120 7.6E-7 T 29-03-2018 THSYN_RS12705 6fc29ae0258955855da4ddc3597fdd3f 363 Gene3D G3DSA:1.10.8.350 121 225 7.0E-37 T 29-03-2018 THSYN_RS31410 854dd86ed0f3a096ac5c6da87a6bc544 141 Pfam PF01894 Uncharacterised protein family UPF0047 20 137 8.6E-34 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 THSYN_RS31410 854dd86ed0f3a096ac5c6da87a6bc544 141 SUPERFAMILY SSF111038 1 140 6.54E-38 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 THSYN_RS31410 854dd86ed0f3a096ac5c6da87a6bc544 141 Gene3D G3DSA:2.60.120.460 1 141 2.7E-38 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 THSYN_RS31410 854dd86ed0f3a096ac5c6da87a6bc544 141 PIRSF PIRSF004681 1 141 2.3E-34 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 THSYN_RS31410 854dd86ed0f3a096ac5c6da87a6bc544 141 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 8 140 1.7E-30 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 THSYN_RS07910 e5485924a89ade59a74ba4b7bf548a9b 268 SUPERFAMILY SSF161098 4 262 8.04E-54 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS07910 e5485924a89ade59a74ba4b7bf548a9b 268 Gene3D G3DSA:1.10.3720.10 6 267 1.9E-39 T 29-03-2018 THSYN_RS07910 e5485924a89ade59a74ba4b7bf548a9b 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 258 1.9E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS08955 cf8c3a9cb8360726e6384a0dbb44dfd4 71 SUPERFAMILY SSF159203 3 69 1.26E-18 T 29-03-2018 IPR024044 NifT/FixU barrel-like domain THSYN_RS08955 cf8c3a9cb8360726e6384a0dbb44dfd4 71 Gene3D G3DSA:2.40.50.240 3 70 1.2E-25 T 29-03-2018 IPR024044 NifT/FixU barrel-like domain THSYN_RS08955 cf8c3a9cb8360726e6384a0dbb44dfd4 71 TIGRFAM TIGR02934 nifT_nitrog: probable nitrogen fixation protein FixT 4 69 3.2E-19 T 29-03-2018 IPR009727 NifT/FixU GO:0009399 THSYN_RS08955 cf8c3a9cb8360726e6384a0dbb44dfd4 71 Pfam PF06988 NifT/FixU protein 1 66 8.3E-23 T 29-03-2018 IPR009727 NifT/FixU GO:0009399 THSYN_RS01070 a38078066bd51bc6e213b960582b5e2d 231 Gene3D G3DSA:3.40.50.620 1 228 1.0E-51 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS01070 a38078066bd51bc6e213b960582b5e2d 231 Pfam PF06508 Queuosine biosynthesis protein QueC 4 218 1.9E-75 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 THSYN_RS01070 a38078066bd51bc6e213b960582b5e2d 231 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 211 5.1E-61 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 THSYN_RS01070 a38078066bd51bc6e213b960582b5e2d 231 PIRSF PIRSF006293 1 228 3.0E-76 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 THSYN_RS01070 a38078066bd51bc6e213b960582b5e2d 231 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 224 56.205 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 THSYN_RS01070 a38078066bd51bc6e213b960582b5e2d 231 SUPERFAMILY SSF52402 1 225 6.17E-63 T 29-03-2018 THSYN_RS12800 bec1f2241ebaca02c098e8a8aae02f40 102 SMART SM00530 6 63 6.0E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS12800 bec1f2241ebaca02c098e8a8aae02f40 102 Gene3D G3DSA:1.10.10.60 1 27 9.6E-6 T 29-03-2018 THSYN_RS12800 bec1f2241ebaca02c098e8a8aae02f40 102 SUPERFAMILY SSF47413 3 57 5.09E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS12800 bec1f2241ebaca02c098e8a8aae02f40 102 Pfam PF01381 Helix-turn-helix 7 57 6.4E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS12800 bec1f2241ebaca02c098e8a8aae02f40 102 Gene3D G3DSA:3.30.1190.10 28 69 9.1E-4 T 29-03-2018 THSYN_RS26875 39ee5ee22d524ae59ab978fff9490fea 319 SMART SM00065 29 183 5.2E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS26875 39ee5ee22d524ae59ab978fff9490fea 319 Gene3D G3DSA:3.30.450.40 11 171 1.6E-20 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS26875 39ee5ee22d524ae59ab978fff9490fea 319 Pfam PF13185 GAF domain 35 170 3.6E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS26875 39ee5ee22d524ae59ab978fff9490fea 319 SUPERFAMILY SSF55781 13 170 4.14E-22 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS21275 6e9b1d73593c683ef6800ff9b519e711 279 Gene3D G3DSA:3.40.50.150 29 253 1.6E-19 T 29-03-2018 THSYN_RS21275 6e9b1d73593c683ef6800ff9b519e711 279 SUPERFAMILY SSF53335 40 250 1.55E-17 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS20470 c0d14d05a7d2f678b29d016525eb3d58 674 TIGRFAM TIGR02688 TIGR02688: TIGR02688 family protein 8 455 5.5E-186 T 29-03-2018 IPR014061 Conserved hypothetical protein CHP02688 THSYN_RS20470 c0d14d05a7d2f678b29d016525eb3d58 674 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 626 644 1.4E-6 T 29-03-2018 THSYN_RS20470 c0d14d05a7d2f678b29d016525eb3d58 674 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 603 622 1.4E-6 T 29-03-2018 THSYN_RS20470 c0d14d05a7d2f678b29d016525eb3d58 674 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 223 242 1.4E-6 T 29-03-2018 THSYN_RS20470 c0d14d05a7d2f678b29d016525eb3d58 674 SUPERFAMILY SSF52540 222 414 1.11E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS20470 c0d14d05a7d2f678b29d016525eb3d58 674 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 510 659 6.2E-10 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 THSYN_RS20470 c0d14d05a7d2f678b29d016525eb3d58 674 TIGRFAM TIGR02653 Lon_rel_chp: conserved hypothetical protein 2 673 0.0 T 29-03-2018 IPR013473 Conserved hypothetical protein CHP02653, peptidase S16 non-peptidase homologue THSYN_RS20470 c0d14d05a7d2f678b29d016525eb3d58 674 SUPERFAMILY SSF54211 494 673 1.14E-23 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS20470 c0d14d05a7d2f678b29d016525eb3d58 674 Pfam PF13337 Putative ATP-dependent Lon protease 11 464 1.2E-205 T 29-03-2018 IPR014061 Conserved hypothetical protein CHP02688 THSYN_RS20470 c0d14d05a7d2f678b29d016525eb3d58 674 Gene3D G3DSA:3.30.230.10 490 671 1.6E-19 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS20470 c0d14d05a7d2f678b29d016525eb3d58 674 Gene3D G3DSA:3.40.50.300 203 360 5.9E-4 T 29-03-2018 THSYN_RS07550 ef95b453910667df7c23e8e87d1488a6 612 Gene3D G3DSA:3.30.420.40 1 156 4.2E-33 T 29-03-2018 THSYN_RS07550 ef95b453910667df7c23e8e87d1488a6 612 Pfam PF16861 Carbamoyltransferase C-terminus 404 593 1.3E-75 T 29-03-2018 IPR031730 Carbamoyltransferase, C-terminal THSYN_RS07550 ef95b453910667df7c23e8e87d1488a6 612 SUPERFAMILY SSF53067 130 215 4.1E-21 T 29-03-2018 THSYN_RS07550 ef95b453910667df7c23e8e87d1488a6 612 SUPERFAMILY SSF53067 1 78 4.1E-21 T 29-03-2018 THSYN_RS07550 ef95b453910667df7c23e8e87d1488a6 612 SUPERFAMILY SSF53067 253 351 4.1E-21 T 29-03-2018 THSYN_RS07550 ef95b453910667df7c23e8e87d1488a6 612 Pfam PF02543 Carbamoyltransferase N-terminus 3 347 7.9E-112 T 29-03-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 THSYN_RS05150 b3257fb85f32703a1c134a0629eedf7c 452 SUPERFAMILY SSF109998 45 221 2.2E-43 T 29-03-2018 IPR027304 Trigger factor/SurA domain THSYN_RS05150 b3257fb85f32703a1c134a0629eedf7c 452 Pfam PF13616 PPIC-type PPIASE domain 303 401 1.2E-25 T 29-03-2018 THSYN_RS05150 b3257fb85f32703a1c134a0629eedf7c 452 SUPERFAMILY SSF54534 192 294 5.04E-26 T 29-03-2018 THSYN_RS05150 b3257fb85f32703a1c134a0629eedf7c 452 Gene3D G3DSA:1.10.4030.10 41 168 8.8E-22 T 29-03-2018 THSYN_RS05150 b3257fb85f32703a1c134a0629eedf7c 452 SUPERFAMILY SSF54534 303 402 7.85E-30 T 29-03-2018 THSYN_RS05150 b3257fb85f32703a1c134a0629eedf7c 452 Hamap MF_01183 Chaperone SurA [surA]. 24 446 32.994 T 29-03-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 THSYN_RS05150 b3257fb85f32703a1c134a0629eedf7c 452 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 339 360 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 THSYN_RS05150 b3257fb85f32703a1c134a0629eedf7c 452 Gene3D G3DSA:3.10.50.40 302 404 9.3E-31 T 29-03-2018 THSYN_RS05150 b3257fb85f32703a1c134a0629eedf7c 452 Gene3D G3DSA:3.10.50.40 183 301 1.5E-25 T 29-03-2018 THSYN_RS05150 b3257fb85f32703a1c134a0629eedf7c 452 Pfam PF00639 PPIC-type PPIASE domain 198 290 4.6E-20 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 THSYN_RS05150 b3257fb85f32703a1c134a0629eedf7c 452 Pfam PF09312 SurA N-terminal domain 45 162 3.2E-35 T 29-03-2018 IPR015391 SurA N-terminal THSYN_RS08565 42dcc0188817d32ff5f21401a52cb1e7 141 SUPERFAMILY SSF48619 38 82 1.71E-9 T 29-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 THSYN_RS08565 42dcc0188817d32ff5f21401a52cb1e7 141 Gene3D G3DSA:1.20.90.10 23 96 1.5E-7 T 29-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 THSYN_RS30440 0e308d5c7f01cf4a84c26f0eafc89124 1514 SUPERFAMILY SSF55874 48 145 2.41E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS30440 0e308d5c7f01cf4a84c26f0eafc89124 1514 Gene3D G3DSA:3.30.565.10 25 274 1.3E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS04525 b32a1cf3dea413a6c159bb65fe938d83 101 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 35 76 3.4E-5 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 THSYN_RS04525 b32a1cf3dea413a6c159bb65fe938d83 101 SUPERFAMILY SSF51621 42 79 2.3E-7 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS04525 b32a1cf3dea413a6c159bb65fe938d83 101 Gene3D G3DSA:3.20.20.60 17 94 8.6E-7 T 29-03-2018 THSYN_RS31360 98ae60250fe79be49779b39537290835 487 SUPERFAMILY SSF53807 8 407 3.04E-70 T 29-03-2018 THSYN_RS31360 98ae60250fe79be49779b39537290835 487 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 12 396 2.4E-31 T 29-03-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 THSYN_RS31360 98ae60250fe79be49779b39537290835 487 Pfam PF08369 Proto-chlorophyllide reductase 57 kD subunit 426 476 1.7E-10 T 29-03-2018 IPR013580 Proto-chlorophyllide/chlorophyllide reductase, C-terminal GO:0015979|GO:0015995|GO:0016491|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31360 98ae60250fe79be49779b39537290835 487 Gene3D G3DSA:3.40.50.1980 10 112 1.1E-4 T 29-03-2018 THSYN_RS31360 98ae60250fe79be49779b39537290835 487 Gene3D G3DSA:3.40.50.1980 116 270 8.3E-25 T 29-03-2018 THSYN_RS31360 98ae60250fe79be49779b39537290835 487 Gene3D G3DSA:3.40.50.1980 284 415 3.2E-18 T 29-03-2018 THSYN_RS31360 98ae60250fe79be49779b39537290835 487 PIRSF PIRSF000163 1 482 1.1E-124 T 29-03-2018 IPR016209 Protochlorophyllide reductase, ChlB, light independent GO:0016730|GO:0046148|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31360 98ae60250fe79be49779b39537290835 487 TIGRFAM TIGR02014 BchZ: chlorophyllide reductase subunit Z 2 473 3.0E-234 T 29-03-2018 IPR010244 Chlorophyllide reductase subunit Z GO:0016730|GO:0030494|GO:0055114 THSYN_RS16055 4d3bbcd89cc8498c8096113fa54884a9 210 Gene3D G3DSA:3.40.50.450 25 160 6.1E-11 T 29-03-2018 THSYN_RS16055 4d3bbcd89cc8498c8096113fa54884a9 210 Gene3D G3DSA:1.20.5.500 2 24 0.0023 T 29-03-2018 THSYN_RS16055 4d3bbcd89cc8498c8096113fa54884a9 210 Pfam PF12694 Putative molybdenum carrier 44 185 1.3E-55 T 29-03-2018 IPR024755 Molybdenum cofactor carrier, putative THSYN_RS16055 4d3bbcd89cc8498c8096113fa54884a9 210 SUPERFAMILY SSF102405 39 138 2.56E-7 T 29-03-2018 THSYN_RS20180 ea52769c138ef5e6ae3298ed430a4f51 88 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 24 84 1.9E-15 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS20180 ea52769c138ef5e6ae3298ed430a4f51 88 Gene3D G3DSA:1.10.150.130 15 88 9.7E-6 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS31835 0fee2d2f8e5dda905ef568afbb70c40a 301 Pfam PF01913 Formylmethanofuran-tetrahydromethanopterin formyltransferase 3 143 5.8E-63 T 29-03-2018 IPR022667 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal GO:0006730|GO:0016740 THSYN_RS31835 0fee2d2f8e5dda905ef568afbb70c40a 301 Pfam PF02741 FTR, proximal lobe 146 296 7.1E-61 T 29-03-2018 IPR002770 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal GO:0006730|GO:0016740 THSYN_RS31835 0fee2d2f8e5dda905ef568afbb70c40a 301 Gene3D G3DSA:3.30.70.520 19 157 2.8E-66 T 29-03-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain THSYN_RS31835 0fee2d2f8e5dda905ef568afbb70c40a 301 SUPERFAMILY SSF55112 3 144 2.35E-63 T 29-03-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain THSYN_RS31835 0fee2d2f8e5dda905ef568afbb70c40a 301 PIRSF PIRSF006414 1 298 1.1E-118 T 29-03-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 THSYN_RS31835 0fee2d2f8e5dda905ef568afbb70c40a 301 Gene3D G3DSA:3.30.70.520 158 296 8.9E-58 T 29-03-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain THSYN_RS31835 0fee2d2f8e5dda905ef568afbb70c40a 301 Hamap MF_00579 Formylmethanofuran--tetrahydromethanopterin formyltransferase [ftr]. 1 297 46.467 T 29-03-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 THSYN_RS31835 0fee2d2f8e5dda905ef568afbb70c40a 301 SUPERFAMILY SSF55112 145 297 1.28E-58 T 29-03-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain THSYN_RS31835 0fee2d2f8e5dda905ef568afbb70c40a 301 TIGRFAM TIGR03119 one_C_fhcD: formylmethanofuran--tetrahydromethanopterin N-formyltransferase 8 296 2.6E-134 T 29-03-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 THSYN_RS07830 4a6649af3c3e8a8d7199e9a4ec88f18b 947 Gene3D G3DSA:3.40.50.410 272 460 9.2E-33 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS07830 4a6649af3c3e8a8d7199e9a4ec88f18b 947 SMART SM00327 277 454 5.3E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS07830 4a6649af3c3e8a8d7199e9a4ec88f18b 947 Pfam PF10021 Uncharacterized protein conserved in bacteria (DUF2263) 690 832 3.1E-36 T 29-03-2018 IPR019261 Domain of unknown function DUF2263 THSYN_RS07830 4a6649af3c3e8a8d7199e9a4ec88f18b 947 SUPERFAMILY SSF52949 843 934 9.65E-9 T 29-03-2018 THSYN_RS07830 4a6649af3c3e8a8d7199e9a4ec88f18b 947 Gene3D G3DSA:3.40.220.10 639 946 3.5E-13 T 29-03-2018 THSYN_RS07830 4a6649af3c3e8a8d7199e9a4ec88f18b 947 SUPERFAMILY SSF53300 275 450 4.59E-33 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS07830 4a6649af3c3e8a8d7199e9a4ec88f18b 947 Pfam PF00092 von Willebrand factor type A domain 279 433 4.7E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS07830 4a6649af3c3e8a8d7199e9a4ec88f18b 947 TIGRFAM TIGR02452 TIGR02452: TIGR02452 family protein 689 939 1.1E-61 T 29-03-2018 IPR012664 Conserved hypothetical protein CHP02452 THSYN_RS32775 9550ef7c9cfbcbf71ce4e4b3e4911708 193 Gene3D G3DSA:3.90.1570.10 1 189 4.5E-30 T 29-03-2018 THSYN_RS32775 9550ef7c9cfbcbf71ce4e4b3e4911708 193 SUPERFAMILY SSF52980 12 189 4.56E-32 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS32775 9550ef7c9cfbcbf71ce4e4b3e4911708 193 Pfam PF05685 Putative restriction endonuclease 12 168 4.4E-22 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS17930 b7fa787d1e7d6a0c79deaf04757a6e9b 304 Pfam PF05175 Methyltransferase small domain 127 210 3.1E-18 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 THSYN_RS17930 b7fa787d1e7d6a0c79deaf04757a6e9b 304 SUPERFAMILY SSF53335 10 288 5.12E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS17930 b7fa787d1e7d6a0c79deaf04757a6e9b 304 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 10 299 1.1E-75 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 THSYN_RS17930 b7fa787d1e7d6a0c79deaf04757a6e9b 304 Gene3D G3DSA:1.10.8.10 9 96 1.2E-13 T 29-03-2018 THSYN_RS17930 b7fa787d1e7d6a0c79deaf04757a6e9b 304 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 1 296 48.859 T 29-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 THSYN_RS17930 b7fa787d1e7d6a0c79deaf04757a6e9b 304 Gene3D G3DSA:3.40.50.150 97 275 5.6E-39 T 29-03-2018 THSYN_RS17930 b7fa787d1e7d6a0c79deaf04757a6e9b 304 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 8 291 1.8E-117 T 29-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 THSYN_RS17930 b7fa787d1e7d6a0c79deaf04757a6e9b 304 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 200 206 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS17930 b7fa787d1e7d6a0c79deaf04757a6e9b 304 PIRSF PIRSF037167 1 303 1.2E-119 T 29-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 THSYN_RS25085 4c04f3858fc9b05fb5800a76fd5e4cba 398 Pfam PF13579 Glycosyl transferase 4-like domain 16 186 4.6E-8 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS25085 4c04f3858fc9b05fb5800a76fd5e4cba 398 Gene3D G3DSA:3.40.50.2000 201 373 3.5E-39 T 29-03-2018 THSYN_RS25085 4c04f3858fc9b05fb5800a76fd5e4cba 398 Gene3D G3DSA:3.40.50.2000 11 200 1.4E-7 T 29-03-2018 THSYN_RS25085 4c04f3858fc9b05fb5800a76fd5e4cba 398 Pfam PF00534 Glycosyl transferases group 1 211 371 3.5E-29 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS25085 4c04f3858fc9b05fb5800a76fd5e4cba 398 SUPERFAMILY SSF53756 15 387 1.06E-59 T 29-03-2018 THSYN_RS10920 23fdebbeed9eb1b49b6c90813d26e5fe 271 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 261 6.0E-74 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THSYN_RS10920 23fdebbeed9eb1b49b6c90813d26e5fe 271 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 29-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THSYN_RS10920 23fdebbeed9eb1b49b6c90813d26e5fe 271 Pfam PF00290 Tryptophan synthase alpha chain 8 250 2.8E-85 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THSYN_RS10920 23fdebbeed9eb1b49b6c90813d26e5fe 271 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 264 34.072 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THSYN_RS10920 23fdebbeed9eb1b49b6c90813d26e5fe 271 Gene3D G3DSA:3.20.20.70 2 270 2.9E-79 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS10920 23fdebbeed9eb1b49b6c90813d26e5fe 271 SUPERFAMILY SSF51366 2 259 7.91E-88 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THSYN_RS01700 8a9976af985f2d67dc69f7753e515bb9 269 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 137 1.0E-6 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS01700 8a9976af985f2d67dc69f7753e515bb9 269 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 14 45 7.1E-6 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS01700 8a9976af985f2d67dc69f7753e515bb9 269 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 3 254 1.0E-94 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 THSYN_RS01700 8a9976af985f2d67dc69f7753e515bb9 269 Gene3D G3DSA:2.160.10.10 1 191 1.2E-39 T 29-03-2018 THSYN_RS01700 8a9976af985f2d67dc69f7753e515bb9 269 PIRSF PIRSF000456 1 263 1.7E-95 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 THSYN_RS01700 8a9976af985f2d67dc69f7753e515bb9 269 SUPERFAMILY SSF51161 2 254 3.07E-62 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS01700 8a9976af985f2d67dc69f7753e515bb9 269 Gene3D G3DSA:1.20.1180.10 192 258 4.2E-19 T 29-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 THSYN_RS01700 8a9976af985f2d67dc69f7753e515bb9 269 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 175 255 1.8E-25 T 29-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 THSYN_RS23645 5d1bcaa1af5ada546833bde1d52d6a4e 389 TIGRFAM TIGR03088 stp2: sugar transferase, PEP-CTERM/EpsH1 system associated 17 387 2.5E-140 T 29-03-2018 IPR017522 Sugar transferase, PEP-CTERM, Stp2 THSYN_RS23645 5d1bcaa1af5ada546833bde1d52d6a4e 389 Pfam PF13692 Glycosyl transferases group 1 211 351 7.4E-30 T 29-03-2018 THSYN_RS23645 5d1bcaa1af5ada546833bde1d52d6a4e 389 Gene3D G3DSA:3.40.50.2000 185 369 2.7E-44 T 29-03-2018 THSYN_RS23645 5d1bcaa1af5ada546833bde1d52d6a4e 389 Gene3D G3DSA:3.40.50.2000 16 184 2.2E-14 T 29-03-2018 THSYN_RS23645 5d1bcaa1af5ada546833bde1d52d6a4e 389 SUPERFAMILY SSF53756 19 388 2.45E-75 T 29-03-2018 THSYN_RS23645 5d1bcaa1af5ada546833bde1d52d6a4e 389 Pfam PF13439 Glycosyltransferase Family 4 29 189 9.7E-20 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS00815 2331d380fb635514232e28201906f114 774 SUPERFAMILY SSF51445 181 618 9.6E-114 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS00815 2331d380fb635514232e28201906f114 774 Gene3D G3DSA:2.60.40.10 113 224 2.2E-30 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS00815 2331d380fb635514232e28201906f114 774 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 110 726 1.6E-284 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 THSYN_RS00815 2331d380fb635514232e28201906f114 774 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 126 208 1.4E-22 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 THSYN_RS00815 2331d380fb635514232e28201906f114 774 Gene3D G3DSA:3.20.20.80 237 636 1.0E-74 T 29-03-2018 THSYN_RS00815 2331d380fb635514232e28201906f114 774 SUPERFAMILY SSF51011 626 729 9.83E-36 T 29-03-2018 THSYN_RS00815 2331d380fb635514232e28201906f114 774 SUPERFAMILY SSF81296 22 116 1.01E-14 T 29-03-2018 IPR014756 Immunoglobulin E-set THSYN_RS00815 2331d380fb635514232e28201906f114 774 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 102 729 45.199 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 THSYN_RS00815 2331d380fb635514232e28201906f114 774 PIRSF PIRSF000463 12 736 5.5E-291 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 THSYN_RS00815 2331d380fb635514232e28201906f114 774 Gene3D G3DSA:2.60.40.10 6 105 1.4E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS00815 2331d380fb635514232e28201906f114 774 SMART SM00642 252 619 6.7E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THSYN_RS00815 2331d380fb635514232e28201906f114 774 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 630 728 1.3E-21 T 29-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 THSYN_RS00815 2331d380fb635514232e28201906f114 774 Pfam PF00128 Alpha amylase, catalytic domain 279 347 6.6E-6 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THSYN_RS00815 2331d380fb635514232e28201906f114 774 Gene3D G3DSA:2.60.40.1180 637 729 1.2E-36 T 29-03-2018 THSYN_RS28780 70b0abb1d2581b514997ec73208bd1d9 265 Gene3D G3DSA:1.10.287.1080 6 125 3.1E-39 T 29-03-2018 THSYN_RS28780 70b0abb1d2581b514997ec73208bd1d9 265 SUPERFAMILY SSF101386 6 106 2.13E-25 T 29-03-2018 THSYN_RS28780 70b0abb1d2581b514997ec73208bd1d9 265 SUPERFAMILY SSF101386 143 240 2.99E-22 T 29-03-2018 THSYN_RS28780 70b0abb1d2581b514997ec73208bd1d9 265 TIGRFAM TIGR00444 mazG: MazG family protein 13 262 3.5E-91 T 29-03-2018 IPR011551 NTP pyrophosphohydrolase MazG THSYN_RS28780 70b0abb1d2581b514997ec73208bd1d9 265 Gene3D G3DSA:1.10.287.1080 143 265 4.0E-23 T 29-03-2018 THSYN_RS28780 70b0abb1d2581b514997ec73208bd1d9 265 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 103 4.5E-28 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core THSYN_RS24345 9b78d5fb42744102cd41fe8d691db6ff 766 SUPERFAMILY SSF52540 558 737 3.05E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24345 9b78d5fb42744102cd41fe8d691db6ff 766 Pfam PF02706 Chain length determinant protein 38 124 3.1E-6 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 THSYN_RS24345 9b78d5fb42744102cd41fe8d691db6ff 766 Pfam PF13807 G-rich domain on putative tyrosine kinase 415 486 9.7E-13 T 29-03-2018 IPR032807 Tyrosine kinase, G-rich domain THSYN_RS24345 9b78d5fb42744102cd41fe8d691db6ff 766 Gene3D G3DSA:3.40.50.300 531 753 2.2E-37 T 29-03-2018 THSYN_RS24345 9b78d5fb42744102cd41fe8d691db6ff 766 Gene3D G3DSA:3.30.1890.10 63 464 6.7E-33 T 29-03-2018 THSYN_RS24345 9b78d5fb42744102cd41fe8d691db6ff 766 Pfam PF13614 AAA domain 566 682 2.6E-10 T 29-03-2018 IPR025669 AAA domain THSYN_RS24345 9b78d5fb42744102cd41fe8d691db6ff 766 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 539 742 9.8E-45 T 29-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 THSYN_RS07690 544855e075c16a9105219528b4d59192 258 SUPERFAMILY SSF53067 1 112 4.75E-23 T 29-03-2018 THSYN_RS07690 544855e075c16a9105219528b4d59192 258 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 17.22 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 THSYN_RS07690 544855e075c16a9105219528b4d59192 258 Pfam PF03309 Type III pantothenate kinase 3 197 5.4E-40 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 THSYN_RS07690 544855e075c16a9105219528b4d59192 258 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 62 249 9.4E-20 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 THSYN_RS07690 544855e075c16a9105219528b4d59192 258 Gene3D G3DSA:3.30.420.40 83 258 8.3E-44 T 29-03-2018 THSYN_RS07690 544855e075c16a9105219528b4d59192 258 SUPERFAMILY SSF53067 118 250 2.07E-22 T 29-03-2018 THSYN_RS01690 ecbbe5374b566778b06f1a32ece84fb1 110 PRINTS PR01591 DNA-binding protein FIS signature 68 80 5.4E-6 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 THSYN_RS01690 ecbbe5374b566778b06f1a32ece84fb1 110 PRINTS PR01591 DNA-binding protein FIS signature 53 68 5.4E-6 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 THSYN_RS01690 ecbbe5374b566778b06f1a32ece84fb1 110 PRINTS PR01591 DNA-binding protein FIS signature 37 53 5.4E-6 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 THSYN_RS01690 ecbbe5374b566778b06f1a32ece84fb1 110 PIRSF PIRSF002097 23 109 3.7E-26 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 THSYN_RS01690 ecbbe5374b566778b06f1a32ece84fb1 110 Gene3D G3DSA:1.10.10.60 26 109 2.9E-16 T 29-03-2018 THSYN_RS01690 ecbbe5374b566778b06f1a32ece84fb1 110 SUPERFAMILY SSF46689 35 108 5.38E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS01690 ecbbe5374b566778b06f1a32ece84fb1 110 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 89 109 2.2E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS01690 ecbbe5374b566778b06f1a32ece84fb1 110 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 72 89 2.2E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS01690 ecbbe5374b566778b06f1a32ece84fb1 110 Pfam PF02954 Bacterial regulatory protein, Fis family 66 106 3.5E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS16190 c1eacbf112fa3f39238ebe157ad20a25 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 76 7.8E-37 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 THSYN_RS16190 c1eacbf112fa3f39238ebe157ad20a25 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site THSYN_RS16190 c1eacbf112fa3f39238ebe157ad20a25 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 77 0.004 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 THSYN_RS16190 c1eacbf112fa3f39238ebe157ad20a25 78 Gene3D G3DSA:1.10.1200.10 1 78 2.6E-28 T 29-03-2018 THSYN_RS16190 c1eacbf112fa3f39238ebe157ad20a25 78 Pfam PF00550 Phosphopantetheine attachment site 6 73 3.8E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain THSYN_RS16190 c1eacbf112fa3f39238ebe157ad20a25 78 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 23.206 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 THSYN_RS16190 c1eacbf112fa3f39238ebe157ad20a25 78 SUPERFAMILY SSF47336 2 77 1.7E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain THSYN_RS13120 8ac6f5aa4c5a899d406b40b545c90af7 192 Pfam PF02600 Disulfide bond formation protein DsbB 12 94 2.7E-10 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 THSYN_RS13120 8ac6f5aa4c5a899d406b40b545c90af7 192 SUPERFAMILY SSF158442 12 121 4.45E-20 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain THSYN_RS13120 8ac6f5aa4c5a899d406b40b545c90af7 192 Gene3D G3DSA:1.20.1550.10 4 168 3.2E-28 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain THSYN_RS10660 dfce14f9fc7cd8a94add036beb785cbf 375 Gene3D G3DSA:3.40.630.10 292 373 1.7E-4 T 29-03-2018 THSYN_RS10660 dfce14f9fc7cd8a94add036beb785cbf 375 Gene3D G3DSA:3.40.630.10 1 279 1.1E-58 T 29-03-2018 THSYN_RS10660 dfce14f9fc7cd8a94add036beb785cbf 375 SUPERFAMILY SSF55031 179 288 1.24E-26 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain THSYN_RS10660 dfce14f9fc7cd8a94add036beb785cbf 375 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 5 373 8.1E-159 T 29-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 THSYN_RS10660 dfce14f9fc7cd8a94add036beb785cbf 375 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 97 135 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 THSYN_RS10660 dfce14f9fc7cd8a94add036beb785cbf 375 Pfam PF01546 Peptidase family M20/M25/M40 62 370 1.7E-43 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 THSYN_RS10660 dfce14f9fc7cd8a94add036beb785cbf 375 Pfam PF07687 Peptidase dimerisation domain 175 279 4.5E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain THSYN_RS10660 dfce14f9fc7cd8a94add036beb785cbf 375 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 2 375 51.504 T 29-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 THSYN_RS10660 dfce14f9fc7cd8a94add036beb785cbf 375 SUPERFAMILY SSF53187 292 374 6.56E-64 T 29-03-2018 THSYN_RS10660 dfce14f9fc7cd8a94add036beb785cbf 375 SUPERFAMILY SSF53187 3 178 6.56E-64 T 29-03-2018 THSYN_RS30985 bfdb6b8e7e5f8826e8a3c5e2fbcca70a 619 Gene3D G3DSA:3.20.20.60 436 598 2.0E-38 T 29-03-2018 THSYN_RS30985 bfdb6b8e7e5f8826e8a3c5e2fbcca70a 619 Gene3D G3DSA:3.20.20.60 135 435 1.1E-28 T 29-03-2018 THSYN_RS30985 bfdb6b8e7e5f8826e8a3c5e2fbcca70a 619 SUPERFAMILY SSF51621 432 606 3.73E-62 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS30985 bfdb6b8e7e5f8826e8a3c5e2fbcca70a 619 SUPERFAMILY SSF51621 120 209 3.73E-62 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS30985 bfdb6b8e7e5f8826e8a3c5e2fbcca70a 619 Pfam PF00224 Pyruvate kinase, barrel domain 137 213 6.7E-10 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS30985 bfdb6b8e7e5f8826e8a3c5e2fbcca70a 619 Pfam PF00224 Pyruvate kinase, barrel domain 364 579 2.9E-37 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS30985 bfdb6b8e7e5f8826e8a3c5e2fbcca70a 619 SUPERFAMILY SSF50800 363 430 1.33E-7 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 269 382 2.5E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 221 4.5E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 Gene3D G3DSA:1.10.287.130 153 217 1.0E-19 T 29-03-2018 THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 SMART SM00388 156 221 5.3E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 Gene3D G3DSA:3.30.565.10 225 392 3.0E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 SMART SM00448 6 119 1.5E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 SUPERFAMILY SSF47384 141 222 1.77E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 SUPERFAMILY SSF52172 6 145 4.7E-36 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 Pfam PF00072 Response regulator receiver domain 8 119 2.2E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 Gene3D G3DSA:3.40.50.2300 3 152 5.3E-36 T 29-03-2018 THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 SUPERFAMILY SSF55874 210 384 5.11E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 381 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 362 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 323 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14865 e275e9e76853770eff9af69c5bfeae89 394 SMART SM00387 268 384 3.6E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00870 b373335acb56756666b1f38463699661 149 Gene3D G3DSA:1.10.287.540 88 119 1.3E-5 T 29-03-2018 THSYN_RS00870 b373335acb56756666b1f38463699661 149 Pfam PF07798 Protein of unknown function (DUF1640) 45 148 2.6E-11 T 29-03-2018 IPR024461 Coiled-coil domain-containing protein 90-like THSYN_RS00870 b373335acb56756666b1f38463699661 149 Gene3D G3DSA:1.20.120.330 33 87 1.8E-5 T 29-03-2018 THSYN_RS00870 b373335acb56756666b1f38463699661 149 SUPERFAMILY SSF58113 45 126 3.27E-6 T 29-03-2018 THSYN_RS29090 b63af98da50cf68966161cbc500cae74 317 Gene3D G3DSA:3.40.50.720 4 317 8.2E-54 T 29-03-2018 THSYN_RS29090 b63af98da50cf68966161cbc500cae74 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 219 2.4E-27 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THSYN_RS29090 b63af98da50cf68966161cbc500cae74 317 SUPERFAMILY SSF51735 4 256 2.35E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS29090 b63af98da50cf68966161cbc500cae74 317 SUPERFAMILY SSF51735 284 315 2.35E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS28945 74081d49f7bbd6d4d063c92c60488aa8 140 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 111 1.2E-28 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 THSYN_RS28945 74081d49f7bbd6d4d063c92c60488aa8 140 PIRSF PIRSF004761 1 115 1.5E-26 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 THSYN_RS08080 889cae1acc7182c8f22526832b6e5ad5 474 SUPERFAMILY SSF46626 278 395 4.31E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS08080 889cae1acc7182c8f22526832b6e5ad5 474 SUPERFAMILY SSF46626 452 474 4.31E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS08080 889cae1acc7182c8f22526832b6e5ad5 474 Gene3D G3DSA:1.10.760.10 269 474 1.4E-24 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS08080 889cae1acc7182c8f22526832b6e5ad5 474 Gene3D G3DSA:1.10.760.10 100 268 0.1 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS08080 889cae1acc7182c8f22526832b6e5ad5 474 Pfam PF00034 Cytochrome c 292 474 1.5E-4 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS31185 7815d1f9278b81c768526659888bf266 326 SUPERFAMILY SSF109709 148 252 1.02E-7 T 29-03-2018 THSYN_RS31185 7815d1f9278b81c768526659888bf266 326 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 87 216 2.4E-18 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 THSYN_RS31185 7815d1f9278b81c768526659888bf266 326 SMART SM00470 67 154 9.2E-14 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS31185 7815d1f9278b81c768526659888bf266 326 Gene3D G3DSA:3.90.1530.10 25 160 2.4E-22 T 29-03-2018 THSYN_RS31185 7815d1f9278b81c768526659888bf266 326 Pfam PF02195 ParB-like nuclease domain 84 153 2.1E-12 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS31185 7815d1f9278b81c768526659888bf266 326 Gene3D G3DSA:1.10.10.10 163 207 0.0043 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS31185 7815d1f9278b81c768526659888bf266 326 SUPERFAMILY SSF110849 87 156 1.13E-16 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS28125 8440f691d13f412f01ef2c454d3f960d 570 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 13 570 3.1E-259 T 29-03-2018 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 THSYN_RS28125 8440f691d13f412f01ef2c454d3f960d 570 SUPERFAMILY SSF160246 7 145 1.57E-34 T 29-03-2018 THSYN_RS28125 8440f691d13f412f01ef2c454d3f960d 570 Gene3D G3DSA:3.30.450.90 155 293 1.7E-47 T 29-03-2018 THSYN_RS28125 8440f691d13f412f01ef2c454d3f960d 570 SUPERFAMILY SSF52540 181 568 4.29E-99 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS28125 8440f691d13f412f01ef2c454d3f960d 570 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 46 151 7.1E-19 T 29-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 THSYN_RS28125 8440f691d13f412f01ef2c454d3f960d 570 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 388 402 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THSYN_RS28125 8440f691d13f412f01ef2c454d3f960d 570 Gene3D G3DSA:3.40.50.300 294 570 1.2E-61 T 29-03-2018 THSYN_RS28125 8440f691d13f412f01ef2c454d3f960d 570 Pfam PF00437 Type II/IV secretion system protein 193 460 1.2E-89 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THSYN_RS03340 6127ee206f1903c1796022cfd625b96b 682 Gene3D G3DSA:3.40.50.410 92 279 1.3E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS03340 6127ee206f1903c1796022cfd625b96b 682 Pfam PF13519 von Willebrand factor type A domain 95 202 3.5E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS03340 6127ee206f1903c1796022cfd625b96b 682 SUPERFAMILY SSF53300 95 280 8.22E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS03340 6127ee206f1903c1796022cfd625b96b 682 SMART SM00327 91 291 2.5E-4 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS03340 6127ee206f1903c1796022cfd625b96b 682 SMART SM00028 415 448 1.6E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS03340 6127ee206f1903c1796022cfd625b96b 682 SUPERFAMILY SSF48452 391 466 3.16E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS03340 6127ee206f1903c1796022cfd625b96b 682 Gene3D G3DSA:1.25.40.10 280 660 4.4E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19685 84d13783b2aab92dbe24b32f6075971c 365 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 28 330 1.2E-145 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 THSYN_RS19685 84d13783b2aab92dbe24b32f6075971c 365 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 365 179.729 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 THSYN_RS19685 84d13783b2aab92dbe24b32f6075971c 365 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 257 330 1.2E-32 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 THSYN_RS19685 84d13783b2aab92dbe24b32f6075971c 365 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 254 331 3.0E-30 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 THSYN_RS19685 84d13783b2aab92dbe24b32f6075971c 365 Gene3D G3DSA:1.10.10.10 261 331 6.5E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19685 84d13783b2aab92dbe24b32f6075971c 365 SMART SM00382 55 182 2.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS19685 84d13783b2aab92dbe24b32f6075971c 365 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 8 239 2.5E-116 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 THSYN_RS19685 84d13783b2aab92dbe24b32f6075971c 365 Gene3D G3DSA:1.10.8.60 188 258 4.5E-31 T 29-03-2018 THSYN_RS19685 84d13783b2aab92dbe24b32f6075971c 365 SUPERFAMILY SSF52540 24 256 9.29E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19685 84d13783b2aab92dbe24b32f6075971c 365 SUPERFAMILY SSF46785 260 334 1.16E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19685 84d13783b2aab92dbe24b32f6075971c 365 Gene3D G3DSA:3.40.50.300 22 185 2.4E-25 T 29-03-2018 THSYN_RS02485 a8c2f65f252cf2f1c346e5600f3b5381 343 Gene3D G3DSA:3.40.50.300 109 265 4.1E-22 T 29-03-2018 THSYN_RS02485 a8c2f65f252cf2f1c346e5600f3b5381 343 Gene3D G3DSA:3.40.50.300 266 338 9.8E-12 T 29-03-2018 THSYN_RS02485 a8c2f65f252cf2f1c346e5600f3b5381 343 Gene3D G3DSA:3.30.450.90 1 92 2.4E-17 T 29-03-2018 THSYN_RS02485 a8c2f65f252cf2f1c346e5600f3b5381 343 SUPERFAMILY SSF52540 2 327 1.33E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02485 a8c2f65f252cf2f1c346e5600f3b5381 343 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 2 332 7.4E-125 T 29-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 THSYN_RS02485 a8c2f65f252cf2f1c346e5600f3b5381 343 Pfam PF00437 Type II/IV secretion system protein 36 262 6.5E-37 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THSYN_RS18585 d6b7e7cfe1ec13319fda035e88c08ba9 217 SUPERFAMILY SSF46894 143 210 3.74E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS18585 d6b7e7cfe1ec13319fda035e88c08ba9 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 6.7E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS18585 d6b7e7cfe1ec13319fda035e88c08ba9 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 6.7E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS18585 d6b7e7cfe1ec13319fda035e88c08ba9 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 6.7E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS18585 d6b7e7cfe1ec13319fda035e88c08ba9 217 Gene3D G3DSA:1.10.10.10 127 214 6.2E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS18585 d6b7e7cfe1ec13319fda035e88c08ba9 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 6.6E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS18585 d6b7e7cfe1ec13319fda035e88c08ba9 217 SUPERFAMILY SSF52172 1 132 1.12E-33 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS18585 d6b7e7cfe1ec13319fda035e88c08ba9 217 SMART SM00421 147 204 3.4E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS18585 d6b7e7cfe1ec13319fda035e88c08ba9 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS18585 d6b7e7cfe1ec13319fda035e88c08ba9 217 Pfam PF00072 Response regulator receiver domain 4 117 2.5E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18585 d6b7e7cfe1ec13319fda035e88c08ba9 217 Gene3D G3DSA:3.40.50.2300 1 126 1.7E-34 T 29-03-2018 THSYN_RS18585 d6b7e7cfe1ec13319fda035e88c08ba9 217 SMART SM00448 2 116 2.2E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS07490 3ad8543d60656c801fb701e7ac60d270 179 Gene3D G3DSA:3.30.70.260 94 178 2.0E-13 T 29-03-2018 THSYN_RS07490 3ad8543d60656c801fb701e7ac60d270 179 Gene3D G3DSA:3.30.70.260 6 86 1.5E-13 T 29-03-2018 THSYN_RS07490 3ad8543d60656c801fb701e7ac60d270 179 SUPERFAMILY SSF55021 92 176 7.64E-18 T 29-03-2018 THSYN_RS07490 3ad8543d60656c801fb701e7ac60d270 179 SUPERFAMILY SSF55021 5 85 3.21E-16 T 29-03-2018 THSYN_RS07490 3ad8543d60656c801fb701e7ac60d270 179 PIRSF PIRSF028103 4 179 1.4E-56 T 29-03-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 THSYN_RS07490 3ad8543d60656c801fb701e7ac60d270 179 Pfam PF13740 ACT domain 7 79 1.2E-21 T 29-03-2018 THSYN_RS04105 ee8c1f5e458bd9b8745adedf4168194f 479 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 402 5.8E-17 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THSYN_RS04105 ee8c1f5e458bd9b8745adedf4168194f 479 SUPERFAMILY SSF53623 113 256 6.41E-40 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS04105 ee8c1f5e458bd9b8745adedf4168194f 479 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 117 141 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 THSYN_RS04105 ee8c1f5e458bd9b8745adedf4168194f 479 SUPERFAMILY SSF53244 317 475 6.41E-36 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THSYN_RS04105 ee8c1f5e458bd9b8745adedf4168194f 479 Pfam PF08245 Mur ligase middle domain 119 242 4.1E-26 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS04105 ee8c1f5e458bd9b8745adedf4168194f 479 Gene3D G3DSA:3.40.1190.10 95 307 6.8E-31 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS04105 ee8c1f5e458bd9b8745adedf4168194f 479 Gene3D G3DSA:3.90.190.20 323 477 2.4E-38 T 29-03-2018 THSYN_RS01360 d5e9b9161edfed379f6b15d46a0cff18 493 Pfam PF05598 Transposase domain (DUF772) 46 91 1.3E-6 T 29-03-2018 IPR008490 Transposase InsH, N-terminal THSYN_RS20400 ea20f9d754e0ca4a6de4f695a3155200 252 SUPERFAMILY SSF46785 161 240 1.68E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS20400 ea20f9d754e0ca4a6de4f695a3155200 252 Gene3D G3DSA:1.10.10.10 162 250 2.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS20400 ea20f9d754e0ca4a6de4f695a3155200 252 SMART SM00419 183 231 1.5E-11 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS20400 ea20f9d754e0ca4a6de4f695a3155200 252 ProSitePatterns PS00042 Crp-type HTH domain signature. 191 214 - T 29-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 THSYN_RS20400 ea20f9d754e0ca4a6de4f695a3155200 252 SMART SM00100 26 147 4.8E-15 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS20400 ea20f9d754e0ca4a6de4f695a3155200 252 Gene3D G3DSA:2.60.120.10 23 161 5.9E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS20400 ea20f9d754e0ca4a6de4f695a3155200 252 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 205 220 5.3E-10 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS20400 ea20f9d754e0ca4a6de4f695a3155200 252 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 189 205 5.3E-10 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS20400 ea20f9d754e0ca4a6de4f695a3155200 252 Pfam PF00027 Cyclic nucleotide-binding domain 46 128 6.0E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS20400 ea20f9d754e0ca4a6de4f695a3155200 252 SUPERFAMILY SSF51206 19 158 2.36E-25 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like THSYN_RS20400 ea20f9d754e0ca4a6de4f695a3155200 252 Pfam PF13545 Crp-like helix-turn-helix domain 164 237 8.9E-17 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS10655 77b1e56d950a854ab31858db61c7cee0 214 Gene3D G3DSA:3.30.420.10 5 176 1.4E-19 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS10655 77b1e56d950a854ab31858db61c7cee0 214 SMART SM00479 12 193 4.2E-5 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THSYN_RS10655 77b1e56d950a854ab31858db61c7cee0 214 SUPERFAMILY SSF53098 8 192 1.83E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS10655 77b1e56d950a854ab31858db61c7cee0 214 Gene3D G3DSA:1.20.5.140 177 193 2.2E-5 T 29-03-2018 THSYN_RS10655 77b1e56d950a854ab31858db61c7cee0 214 Pfam PF00929 Exonuclease 14 183 7.5E-6 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THSYN_RS12345 e7894e7afbb14a3614f1f5ddce0df534 185 Pfam PF00255 Glutathione peroxidase 33 139 5.9E-35 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 THSYN_RS12345 e7894e7afbb14a3614f1f5ddce0df534 185 PIRSF PIRSF000303 17 185 8.1E-57 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 THSYN_RS12345 e7894e7afbb14a3614f1f5ddce0df534 185 ProSitePatterns PS00460 Glutathione peroxidases active site. 53 68 - T 29-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 THSYN_RS12345 e7894e7afbb14a3614f1f5ddce0df534 185 PRINTS PR01011 Glutathione peroxidase family signature 86 102 1.4E-16 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 THSYN_RS12345 e7894e7afbb14a3614f1f5ddce0df534 185 PRINTS PR01011 Glutathione peroxidase family signature 51 68 1.4E-16 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 THSYN_RS12345 e7894e7afbb14a3614f1f5ddce0df534 185 PRINTS PR01011 Glutathione peroxidase family signature 147 156 1.4E-16 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 THSYN_RS12345 e7894e7afbb14a3614f1f5ddce0df534 185 SUPERFAMILY SSF52833 30 185 2.24E-50 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS12345 e7894e7afbb14a3614f1f5ddce0df534 185 Gene3D G3DSA:3.40.30.10 31 185 8.9E-35 T 29-03-2018 THSYN_RS29170 65066aac24b4d659d8d1b9bde466c69d 179 PRINTS PR00125 ATP synthase delta subunit signature 137 152 3.4E-24 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29170 65066aac24b4d659d8d1b9bde466c69d 179 PRINTS PR00125 ATP synthase delta subunit signature 76 87 3.4E-24 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29170 65066aac24b4d659d8d1b9bde466c69d 179 PRINTS PR00125 ATP synthase delta subunit signature 8 27 3.4E-24 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29170 65066aac24b4d659d8d1b9bde466c69d 179 PRINTS PR00125 ATP synthase delta subunit signature 152 170 3.4E-24 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29170 65066aac24b4d659d8d1b9bde466c69d 179 PRINTS PR00125 ATP synthase delta subunit signature 87 101 3.4E-24 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29170 65066aac24b4d659d8d1b9bde466c69d 179 Hamap MF_01416 ATP synthase subunit delta [atpD]. 4 179 18.607 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29170 65066aac24b4d659d8d1b9bde466c69d 179 Gene3D G3DSA:1.10.520.20 3 108 6.6E-26 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29170 65066aac24b4d659d8d1b9bde466c69d 179 SUPERFAMILY SSF47928 4 105 3.79E-23 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29170 65066aac24b4d659d8d1b9bde466c69d 179 Pfam PF00213 ATP synthase delta (OSCP) subunit 8 177 5.9E-49 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29170 65066aac24b4d659d8d1b9bde466c69d 179 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 139 158 - T 29-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29170 65066aac24b4d659d8d1b9bde466c69d 179 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 8 177 7.3E-43 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS31020 f32db2d41e0723cf8e96e7ac78d499f5 809 Pfam PF11339 Protein of unknown function (DUF3141) 86 630 3.0E-230 T 29-03-2018 IPR024501 Protein of unknown function DUF3141 THSYN_RS31020 f32db2d41e0723cf8e96e7ac78d499f5 809 Gene3D G3DSA:3.40.50.1820 21 455 1.1E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS31020 f32db2d41e0723cf8e96e7ac78d499f5 809 SUPERFAMILY SSF53474 142 453 2.17E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS31870 ec6c3bbad5dbda793fa5358476b44574 630 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 11 630 33.956 T 29-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup THSYN_RS31870 ec6c3bbad5dbda793fa5358476b44574 630 Pfam PF02705 K+ potassium transporter 20 552 1.5E-208 T 29-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 THSYN_RS02575 e20ec940d22f27fc33919cf0ce9a52a1 276 SUPERFAMILY SSF54506 3 274 3.54E-57 T 29-03-2018 THSYN_RS02575 e20ec940d22f27fc33919cf0ce9a52a1 276 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 29-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THSYN_RS02575 e20ec940d22f27fc33919cf0ce9a52a1 276 Gene3D G3DSA:3.10.310.10 1 126 7.1E-51 T 29-03-2018 THSYN_RS02575 e20ec940d22f27fc33919cf0ce9a52a1 276 Pfam PF01678 Diaminopimelate epimerase 5 123 2.1E-31 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THSYN_RS02575 e20ec940d22f27fc33919cf0ce9a52a1 276 Pfam PF01678 Diaminopimelate epimerase 154 269 1.1E-28 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THSYN_RS02575 e20ec940d22f27fc33919cf0ce9a52a1 276 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 274 5.0E-90 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THSYN_RS02575 e20ec940d22f27fc33919cf0ce9a52a1 276 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 276 39.317 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THSYN_RS02575 e20ec940d22f27fc33919cf0ce9a52a1 276 Gene3D G3DSA:3.10.310.10 127 263 4.5E-50 T 29-03-2018 THSYN_RS26550 c0c3361af34fb921276d19652bf51375 112 SUPERFAMILY SSF54292 5 105 3.14E-29 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS26550 c0c3361af34fb921276d19652bf51375 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 91 1.9E-10 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS26550 c0c3361af34fb921276d19652bf51375 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 110 6.9E-51 T 29-03-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 THSYN_RS26550 c0c3361af34fb921276d19652bf51375 112 PRINTS PR00355 Adrenodoxin signature 42 52 8.6E-9 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 THSYN_RS26550 c0c3361af34fb921276d19652bf51375 112 PRINTS PR00355 Adrenodoxin signature 60 74 8.6E-9 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 THSYN_RS26550 c0c3361af34fb921276d19652bf51375 112 PRINTS PR00355 Adrenodoxin signature 83 91 8.6E-9 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 THSYN_RS26550 c0c3361af34fb921276d19652bf51375 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 29-03-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 THSYN_RS26550 c0c3361af34fb921276d19652bf51375 112 Gene3D G3DSA:3.10.20.30 5 112 4.5E-28 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS12295 d700c166fdd18de4ab4c8a16c52dbeca 703 Pfam PF12867 DinB superfamily 30 163 2.2E-8 T 29-03-2018 IPR024775 DinB-like domain THSYN_RS12295 d700c166fdd18de4ab4c8a16c52dbeca 703 Pfam PF03781 Sulfatase-modifying factor enzyme 1 195 448 2.0E-30 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS12295 d700c166fdd18de4ab4c8a16c52dbeca 703 TIGRFAM TIGR04344 ovoA_Nterm: 5-histidylcysteine sulfoxide synthase 9 448 4.3E-202 T 29-03-2018 IPR027577 5-histidylcysteine sulfoxide synthase THSYN_RS12295 d700c166fdd18de4ab4c8a16c52dbeca 703 TIGRFAM TIGR04345 ovoA_Cterm: putative 4-mercaptohistidine N1-methyltranferase 461 702 1.5E-99 T 29-03-2018 IPR027625 Putative 4-mercaptohistidine N1-methyltranferase, OvoA C-terminal domain THSYN_RS12295 d700c166fdd18de4ab4c8a16c52dbeca 703 Gene3D G3DSA:3.90.1580.10 183 457 1.4E-46 T 29-03-2018 THSYN_RS12295 d700c166fdd18de4ab4c8a16c52dbeca 703 SUPERFAMILY SSF56436 192 449 2.45E-55 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS12295 d700c166fdd18de4ab4c8a16c52dbeca 703 SUPERFAMILY SSF53335 468 544 1.99E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS12295 d700c166fdd18de4ab4c8a16c52dbeca 703 SUPERFAMILY SSF53335 571 663 1.99E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS12295 d700c166fdd18de4ab4c8a16c52dbeca 703 Gene3D G3DSA:3.40.50.150 482 703 5.6E-25 T 29-03-2018 THSYN_RS12295 d700c166fdd18de4ab4c8a16c52dbeca 703 Pfam PF13489 Methyltransferase domain 488 647 4.7E-8 T 29-03-2018 THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 119 129 1.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 160 173 1.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 101 115 1.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 136 154 1.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 Gene3D G3DSA:1.20.120.160 359 521 6.8E-14 T 29-03-2018 THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 SUPERFAMILY SSF55874 2 174 5.5E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 Gene3D G3DSA:3.40.50.2300 183 317 1.9E-36 T 29-03-2018 THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 Pfam PF00072 Response regulator receiver domain 199 307 4.1E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 Gene3D G3DSA:3.30.565.10 17 182 2.5E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 Pfam PF01627 Hpt domain 365 437 6.3E-8 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 SUPERFAMILY SSF47226 293 306 1.26E-17 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 SUPERFAMILY SSF47226 346 430 1.26E-17 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 60 174 2.9E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 SUPERFAMILY SSF52172 197 315 8.68E-37 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 SMART SM00448 197 310 1.3E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS14860 6a1e985f92486d81cb852780041030f7 547 SMART SM00387 60 176 7.7E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 866 196.577 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 3.7E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 PRINTS PR00980 Alanyl-tRNA synthetase signature 296 309 3.7E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 PRINTS PR00980 Alanyl-tRNA synthetase signature 75 86 3.7E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 PRINTS PR00980 Alanyl-tRNA synthetase signature 272 288 3.7E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 3.7E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 SUPERFAMILY SSF50447 445 543 1.17E-17 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 Gene3D G3DSA:3.30.930.10 1 242 4.0E-112 T 29-03-2018 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 Pfam PF01411 tRNA synthetases class II (A) 6 547 2.0E-219 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 SUPERFAMILY SSF55186 543 702 2.49E-49 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 SMART SM00863 644 687 1.9E-18 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 Gene3D G3DSA:3.30.980.10 544 704 2.3E-42 T 29-03-2018 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 SUPERFAMILY SSF101353 246 436 1.09E-57 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 SUPERFAMILY SSF55681 3 245 1.71E-106 T 29-03-2018 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 845 0.0 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 Pfam PF02272 DHHA1 domain 726 862 9.2E-26 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 THSYN_RS28020 16b530f6509199aa860fe216b934647b 888 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 644 687 7.0E-15 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 THSYN_RS04255 5e70d64eae0d3151ee9da75b53802f5c 714 SMART SM00052 461 705 6.3E-9 T 29-03-2018 IPR001633 EAL domain THSYN_RS04255 5e70d64eae0d3151ee9da75b53802f5c 714 Gene3D G3DSA:3.30.70.270 288 453 3.9E-19 T 29-03-2018 THSYN_RS04255 5e70d64eae0d3151ee9da75b53802f5c 714 Gene3D G3DSA:3.20.20.450 467 708 1.0E-31 T 29-03-2018 IPR001633 EAL domain THSYN_RS04255 5e70d64eae0d3151ee9da75b53802f5c 714 Gene3D G3DSA:3.40.50.2300 16 154 0.015 T 29-03-2018 THSYN_RS04255 5e70d64eae0d3151ee9da75b53802f5c 714 SMART SM00267 273 449 8.0E-7 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS04255 5e70d64eae0d3151ee9da75b53802f5c 714 SMART SM00448 157 270 1.3E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS04255 5e70d64eae0d3151ee9da75b53802f5c 714 SUPERFAMILY SSF55073 294 446 7.3E-14 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS04255 5e70d64eae0d3151ee9da75b53802f5c 714 SUPERFAMILY SSF52172 158 283 5.69E-26 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS04255 5e70d64eae0d3151ee9da75b53802f5c 714 Pfam PF00563 EAL domain 478 700 6.0E-28 T 29-03-2018 IPR001633 EAL domain THSYN_RS04255 5e70d64eae0d3151ee9da75b53802f5c 714 Gene3D G3DSA:3.40.50.2300 155 287 6.9E-25 T 29-03-2018 THSYN_RS04255 5e70d64eae0d3151ee9da75b53802f5c 714 Pfam PF00072 Response regulator receiver domain 159 270 4.5E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS04255 5e70d64eae0d3151ee9da75b53802f5c 714 Pfam PF00990 Diguanylate cyclase, GGDEF domain 289 442 3.5E-8 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS04255 5e70d64eae0d3151ee9da75b53802f5c 714 SUPERFAMILY SSF141868 473 704 1.83E-28 T 29-03-2018 IPR001633 EAL domain THSYN_RS16705 25451767007df608078b256b091e6709 171 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 85.188 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 THSYN_RS16705 25451767007df608078b256b091e6709 171 Pfam PF03477 ATP cone domain 50 136 4.9E-16 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 THSYN_RS16705 25451767007df608078b256b091e6709 171 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 3.8E-61 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 THSYN_RS24485 8c02382e386a60d62b44a73ac4276ce4 85 Pfam PF01016 Ribosomal L27 protein 2 82 9.9E-37 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24485 8c02382e386a60d62b44a73ac4276ce4 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 3.0E-12 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24485 8c02382e386a60d62b44a73ac4276ce4 85 Gene3D G3DSA:2.40.50.100 20 84 2.4E-27 T 29-03-2018 THSYN_RS24485 8c02382e386a60d62b44a73ac4276ce4 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS24485 8c02382e386a60d62b44a73ac4276ce4 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 9.9E-38 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24485 8c02382e386a60d62b44a73ac4276ce4 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 9.9E-38 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24485 8c02382e386a60d62b44a73ac4276ce4 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 9.9E-38 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24485 8c02382e386a60d62b44a73ac4276ce4 85 SUPERFAMILY SSF110324 2 81 2.09E-32 T 29-03-2018 THSYN_RS24485 8c02382e386a60d62b44a73ac4276ce4 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.315 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24485 8c02382e386a60d62b44a73ac4276ce4 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 6.4E-40 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS22165 c8bca88a7584fcc350eb48fbb1505ee2 392 Gene3D G3DSA:3.40.50.300 180 316 5.8E-5 T 29-03-2018 THSYN_RS22165 c8bca88a7584fcc350eb48fbb1505ee2 392 SUPERFAMILY SSF52540 275 391 4.02E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22165 c8bca88a7584fcc350eb48fbb1505ee2 392 SUPERFAMILY SSF52540 188 248 4.02E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22165 c8bca88a7584fcc350eb48fbb1505ee2 392 Gene3D G3DSA:3.40.50.10140 2 155 2.0E-5 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS22165 c8bca88a7584fcc350eb48fbb1505ee2 392 Pfam PF08357 SEFIR domain 4 87 1.6E-4 T 29-03-2018 IPR013568 SEFIR domain THSYN_RS31040 a41d1a755b41b0da214eaeb36b057cdb 491 SUPERFAMILY SSF63825 258 358 1.65E-10 T 29-03-2018 THSYN_RS31040 a41d1a755b41b0da214eaeb36b057cdb 491 SUPERFAMILY SSF63825 190 230 1.65E-10 T 29-03-2018 THSYN_RS31040 a41d1a755b41b0da214eaeb36b057cdb 491 SUPERFAMILY SSF63829 64 228 9.48E-6 T 29-03-2018 THSYN_RS31040 a41d1a755b41b0da214eaeb36b057cdb 491 SUPERFAMILY SSF63829 255 273 9.48E-6 T 29-03-2018 THSYN_RS31040 a41d1a755b41b0da214eaeb36b057cdb 491 Pfam PF13449 Esterase-like activity of phytase 59 430 2.6E-59 T 29-03-2018 IPR027372 Phytase-like domain THSYN_RS31040 a41d1a755b41b0da214eaeb36b057cdb 491 Gene3D G3DSA:2.120.10.30 267 449 0.019 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS31040 a41d1a755b41b0da214eaeb36b057cdb 491 Gene3D G3DSA:2.130.10.10 161 266 4.4E-9 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS22105 3a9581caecd605888d525a654d4029da 478 Hamap MF_01603 Bifunctional protein HldE [hldE]. 4 474 41.674 T 29-03-2018 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 THSYN_RS22105 3a9581caecd605888d525a654d4029da 478 Gene3D G3DSA:3.40.1190.20 3 310 1.3E-60 T 29-03-2018 IPR029056 Ribokinase-like THSYN_RS22105 3a9581caecd605888d525a654d4029da 478 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 343 408 1.7E-18 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THSYN_RS22105 3a9581caecd605888d525a654d4029da 478 Gene3D G3DSA:3.40.50.620 323 477 3.1E-25 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS22105 3a9581caecd605888d525a654d4029da 478 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 51 74 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 THSYN_RS22105 3a9581caecd605888d525a654d4029da 478 SUPERFAMILY SSF53613 12 308 3.74E-61 T 29-03-2018 IPR029056 Ribokinase-like THSYN_RS22105 3a9581caecd605888d525a654d4029da 478 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 333 472 1.0E-57 T 29-03-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 THSYN_RS22105 3a9581caecd605888d525a654d4029da 478 Pfam PF01467 Cytidylyltransferase-like 345 435 2.3E-15 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THSYN_RS22105 3a9581caecd605888d525a654d4029da 478 Pfam PF00294 pfkB family carbohydrate kinase 11 302 7.5E-47 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB THSYN_RS22105 3a9581caecd605888d525a654d4029da 478 SUPERFAMILY SSF52374 342 471 3.66E-22 T 29-03-2018 THSYN_RS22105 3a9581caecd605888d525a654d4029da 478 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 6 312 2.0E-119 T 29-03-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 THSYN_RS29255 aada3f05762a66369f9bee7b36456ca2 624 SUPERFAMILY SSF51905 6 66 1.3E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS29255 aada3f05762a66369f9bee7b36456ca2 624 SUPERFAMILY SSF51905 97 261 1.3E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS29255 aada3f05762a66369f9bee7b36456ca2 624 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 622 1.9E-265 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 THSYN_RS29255 aada3f05762a66369f9bee7b36456ca2 624 Gene3D G3DSA:3.50.50.60 5 264 9.5E-72 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS29255 aada3f05762a66369f9bee7b36456ca2 624 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 THSYN_RS29255 aada3f05762a66369f9bee7b36456ca2 624 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 624 41.898 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 THSYN_RS29255 aada3f05762a66369f9bee7b36456ca2 624 Pfam PF01134 Glucose inhibited division protein A 8 398 4.5E-162 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 THSYN_RS29255 aada3f05762a66369f9bee7b36456ca2 624 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 THSYN_RS29255 aada3f05762a66369f9bee7b36456ca2 624 Pfam PF13932 GidA associated domain 402 616 1.1E-71 T 29-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 THSYN_RS29255 aada3f05762a66369f9bee7b36456ca2 624 SMART SM01228 546 617 1.8E-38 T 29-03-2018 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 SUPERFAMILY SSF81886 648 868 1.83E-82 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 SUPERFAMILY SSF81886 913 925 1.83E-82 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 Gene3D G3DSA:3.40.50.300 331 446 7.7E-9 T 29-03-2018 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 Gene3D G3DSA:3.40.50.300 9 286 4.4E-45 T 29-03-2018 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 SMART SM00957 6 432 1.6E-292 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 Pfam PF01043 SecA preprotein cross-linking domain 260 388 1.1E-37 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 Gene3D G3DSA:3.40.50.300 447 662 2.4E-56 T 29-03-2018 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 SUPERFAMILY SSF52540 398 445 3.01E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 SUPERFAMILY SSF52540 4 170 3.01E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 SUPERFAMILY SSF52540 198 255 3.01E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 860 19.994 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 188 846 5.5E-270 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 SUPERFAMILY SSF52540 447 646 2.37E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 Pfam PF07517 SecA DEAD-like domain 6 432 4.5E-125 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 Pfam PF07516 SecA Wing and Scaffold domain 645 856 2.0E-68 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 Pfam PF02810 SEC-C motif 917 935 2.1E-10 T 29-03-2018 IPR004027 SEC-C motif THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 PRINTS PR00906 SecA protein signature 369 391 5.3E-57 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 PRINTS PR00906 SecA protein signature 101 115 5.3E-57 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 PRINTS PR00906 SecA protein signature 63 87 5.3E-57 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 PRINTS PR00906 SecA protein signature 443 456 5.3E-57 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 PRINTS PR00906 SecA protein signature 406 423 5.3E-57 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 PRINTS PR00906 SecA protein signature 117 127 5.3E-57 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 SMART SM00958 255 388 3.2E-78 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 Gene3D G3DSA:1.10.3060.10 663 774 2.3E-30 T 29-03-2018 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 Gene3D G3DSA:1.10.3060.10 775 869 6.1E-25 T 29-03-2018 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 ProSitePatterns PS01312 SecA family signature. 530 545 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 THSYN_RS03470 73c3a78f586ad3cf2906148f88b62046 937 SUPERFAMILY SSF81767 254 398 5.36E-42 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 THSYN_RS32450 946a8d9a17bf7f78c1ee3042288ab8a5 126 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 125 13.059 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS32450 946a8d9a17bf7f78c1ee3042288ab8a5 126 SUPERFAMILY SSF88723 1 123 5.61E-18 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS32450 946a8d9a17bf7f78c1ee3042288ab8a5 126 Pfam PF01850 PIN domain 1 121 1.9E-17 T 29-03-2018 IPR002716 PIN domain THSYN_RS32450 946a8d9a17bf7f78c1ee3042288ab8a5 126 Gene3D G3DSA:3.40.50.1010 1 125 1.2E-15 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Gene3D G3DSA:1.25.40.10 840 930 1.8E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Pfam PF13428 Tetratricopeptide repeat 784 824 7.6E-7 T 29-03-2018 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Gene3D G3DSA:1.25.40.10 596 691 4.5E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SUPERFAMILY SSF48452 461 750 6.07E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Gene3D G3DSA:1.25.40.10 520 595 2.4E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Gene3D G3DSA:1.25.40.10 289 326 1.0E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Gene3D G3DSA:1.25.40.10 136 191 6.3E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Gene3D G3DSA:1.25.40.10 472 519 2.9E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Gene3D G3DSA:1.25.40.10 192 288 1.2E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Gene3D G3DSA:1.25.40.10 376 471 2.9E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Gene3D G3DSA:1.25.40.10 32 124 5.8E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Gene3D G3DSA:1.25.40.10 790 839 9.4E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 67 100 410.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 273 306 260.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 579 612 230.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 137 170 0.013 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 613 646 290.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 477 510 0.016 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 171 204 10.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 205 238 370.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 850 883 480.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 307 340 0.068 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 647 680 210.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 375 408 360.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 239 272 97.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 511 544 0.58 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SMART SM00028 783 816 9.3E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Pfam PF14559 Tetratricopeptide repeat 148 210 5.0E-7 T 29-03-2018 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Pfam PF14559 Tetratricopeptide repeat 488 554 1.9E-6 T 29-03-2018 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Pfam PF14559 Tetratricopeptide repeat 860 922 3.3E-9 T 29-03-2018 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Pfam PF14559 Tetratricopeptide repeat 557 622 3.1E-7 T 29-03-2018 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SUPERFAMILY SSF48452 326 436 1.94E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SUPERFAMILY SSF48452 720 909 4.17E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Pfam PF13432 Tetratricopeptide repeat 277 340 1.1E-5 T 29-03-2018 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Pfam PF13432 Tetratricopeptide repeat 347 409 1.7E-5 T 29-03-2018 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 TIGRFAM TIGR02917 PEP_TPR_lipo: putative PEP-CTERM system TPR-repeat lipoprotein 37 911 3.9E-158 T 29-03-2018 IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Gene3D G3DSA:1.25.40.10 719 789 3.1E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 Gene3D G3DSA:1.25.40.10 327 375 1.1E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SUPERFAMILY SSF48452 42 166 4.34E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19570 794044eb4289b4d8fbf03f686d190bc5 930 SUPERFAMILY SSF48452 143 363 2.13E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS25670 bf7276f66fea7ce27762a2b86c9b8c52 419 Gene3D G3DSA:3.60.21.10 75 246 6.8E-18 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS25670 bf7276f66fea7ce27762a2b86c9b8c52 419 Gene3D G3DSA:3.60.21.10 1 74 4.5E-12 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS25670 bf7276f66fea7ce27762a2b86c9b8c52 419 Pfam PF00149 Calcineurin-like phosphoesterase 1 196 1.1E-10 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS25670 bf7276f66fea7ce27762a2b86c9b8c52 419 PIRSF PIRSF033091 1 414 5.3E-104 T 29-03-2018 IPR014576 Predicted phosphoesterase, YhaO type THSYN_RS25670 bf7276f66fea7ce27762a2b86c9b8c52 419 SUPERFAMILY SSF56300 1 268 1.67E-48 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS20695 6e1c1ff5a51bf9cf4e6b0faaafa13baf 415 SUPERFAMILY SSF52507 4 178 7.46E-61 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 THSYN_RS20695 6e1c1ff5a51bf9cf4e6b0faaafa13baf 415 Gene3D G3DSA:3.40.50.1950 1 188 1.1E-56 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 THSYN_RS20695 6e1c1ff5a51bf9cf4e6b0faaafa13baf 415 Pfam PF02441 Flavoprotein 8 178 3.2E-45 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 THSYN_RS20695 6e1c1ff5a51bf9cf4e6b0faaafa13baf 415 SUPERFAMILY SSF102645 199 411 4.05E-71 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 THSYN_RS20695 6e1c1ff5a51bf9cf4e6b0faaafa13baf 415 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 201 382 9.1E-66 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 THSYN_RS20695 6e1c1ff5a51bf9cf4e6b0faaafa13baf 415 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 8 407 5.6E-129 T 29-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 THSYN_RS20695 6e1c1ff5a51bf9cf4e6b0faaafa13baf 415 Gene3D G3DSA:3.40.50.10300 195 414 2.0E-61 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 THSYN_RS07430 fd07ea3c4e3ee5392989587d7c303a68 260 Pfam PF01427 D-ala-D-ala dipeptidase 188 255 1.1E-15 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 THSYN_RS07430 fd07ea3c4e3ee5392989587d7c303a68 260 Pfam PF01427 D-ala-D-ala dipeptidase 33 156 5.3E-16 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 THSYN_RS07430 fd07ea3c4e3ee5392989587d7c303a68 260 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 33 254 30.873 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 THSYN_RS07430 fd07ea3c4e3ee5392989587d7c303a68 260 SUPERFAMILY SSF55166 31 255 2.86E-60 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS07430 fd07ea3c4e3ee5392989587d7c303a68 260 PIRSF PIRSF026671 6 258 1.9E-66 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 THSYN_RS07430 fd07ea3c4e3ee5392989587d7c303a68 260 Gene3D G3DSA:3.30.1380.10 30 256 1.1E-67 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS24045 a988e7cae64fdac22a780d191ecaed08 251 SUPERFAMILY SSF63892 9 244 2.88E-95 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 THSYN_RS24045 a988e7cae64fdac22a780d191ecaed08 251 Gene3D G3DSA:3.20.20.70 9 243 8.8E-99 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS24045 a988e7cae64fdac22a780d191ecaed08 251 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 250 120.639 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 THSYN_RS24045 a988e7cae64fdac22a780d191ecaed08 251 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 11 243 4.3E-98 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 THSYN_RS24045 a988e7cae64fdac22a780d191ecaed08 251 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 11 243 1.6E-92 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 THSYN_RS25175 c404f1e1b3667983adc3a59602725b46 253 Pfam PF00483 Nucleotidyl transferase 15 200 3.1E-10 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THSYN_RS25175 c404f1e1b3667983adc3a59602725b46 253 Gene3D G3DSA:3.90.550.10 10 250 7.6E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS25175 c404f1e1b3667983adc3a59602725b46 253 SUPERFAMILY SSF53448 11 249 2.48E-37 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS25175 c404f1e1b3667983adc3a59602725b46 253 PIRSF PIRSF028162 10 250 9.3E-73 T 29-03-2018 IPR016873 Capsular polysaccharide biosynthesis protein, BcbE, predicted THSYN_RS32700 984d8b0e56d5c792b9f6d423952a3d7b 785 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 30 512 2.1E-154 T 29-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein THSYN_RS32700 984d8b0e56d5c792b9f6d423952a3d7b 785 SUPERFAMILY SSF69255 372 460 1.05E-33 T 29-03-2018 THSYN_RS32700 984d8b0e56d5c792b9f6d423952a3d7b 785 SUPERFAMILY SSF69349 450 651 2.28E-43 T 29-03-2018 THSYN_RS32700 984d8b0e56d5c792b9f6d423952a3d7b 785 Pfam PF05954 Phage late control gene D protein (GPD) 34 335 4.9E-102 T 29-03-2018 THSYN_RS32700 984d8b0e56d5c792b9f6d423952a3d7b 785 SUPERFAMILY SSF69279 194 372 2.72E-38 T 29-03-2018 THSYN_RS32700 984d8b0e56d5c792b9f6d423952a3d7b 785 Gene3D G3DSA:2.40.50.230 378 460 5.4E-36 T 29-03-2018 IPR006531 Gp5 N-terminal THSYN_RS32700 984d8b0e56d5c792b9f6d423952a3d7b 785 SUPERFAMILY SSF69279 17 190 5.53E-61 T 29-03-2018 THSYN_RS32700 984d8b0e56d5c792b9f6d423952a3d7b 785 Gene3D G3DSA:2.60.40.10 697 780 3.5E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS32700 984d8b0e56d5c792b9f6d423952a3d7b 785 Gene3D G3DSA:3.55.50.10 103 195 4.2E-33 T 29-03-2018 THSYN_RS32700 984d8b0e56d5c792b9f6d423952a3d7b 785 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 16 530 1.9E-192 T 29-03-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset THSYN_RS13880 045077378978510dfba32f43cffd44dd 1095 SUPERFAMILY SSF53474 825 1018 5.53E-14 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS13880 045077378978510dfba32f43cffd44dd 1095 SUPERFAMILY SSF52129 194 257 5.44E-12 T 29-03-2018 IPR029030 Caspase-like domain THSYN_RS13880 045077378978510dfba32f43cffd44dd 1095 SUPERFAMILY SSF52129 3 156 5.44E-12 T 29-03-2018 IPR029030 Caspase-like domain THSYN_RS13880 045077378978510dfba32f43cffd44dd 1095 Gene3D G3DSA:3.40.50.1820 807 1091 1.3E-13 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS13880 045077378978510dfba32f43cffd44dd 1095 Gene3D G3DSA:3.40.50.1460 5 270 8.7E-52 T 29-03-2018 THSYN_RS13880 045077378978510dfba32f43cffd44dd 1095 Pfam PF00656 Caspase domain 9 264 2.3E-22 T 29-03-2018 THSYN_RS17710 8b69ca685e1d37dd4df3caaa7751579c 438 SUPERFAMILY SSF52540 1 119 4.52E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17710 8b69ca685e1d37dd4df3caaa7751579c 438 SUPERFAMILY SSF52540 261 400 4.52E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17710 8b69ca685e1d37dd4df3caaa7751579c 438 Gene3D G3DSA:3.40.50.300 1 392 3.2E-24 T 29-03-2018 THSYN_RS17710 8b69ca685e1d37dd4df3caaa7751579c 438 PIRSF PIRSF029347 129 405 6.1E-19 T 29-03-2018 IPR014555 RecF-like THSYN_RS17710 8b69ca685e1d37dd4df3caaa7751579c 438 PIRSF PIRSF029347 1 54 5.9E-12 T 29-03-2018 IPR014555 RecF-like THSYN_RS17710 8b69ca685e1d37dd4df3caaa7751579c 438 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 23 376 1.2E-27 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS18045 78384543029685ce802dbe12a5ffcdd8 290 Pfam PF08849 Putative inner membrane protein (DUF1819) 15 135 1.7E-11 T 29-03-2018 IPR014948 Protein of unknown function DUF1819, putative inner membrane THSYN_RS18045 78384543029685ce802dbe12a5ffcdd8 290 Pfam PF08849 Putative inner membrane protein (DUF1819) 174 221 5.4E-6 T 29-03-2018 IPR014948 Protein of unknown function DUF1819, putative inner membrane THSYN_RS18045 78384543029685ce802dbe12a5ffcdd8 290 Gene3D G3DSA:1.10.3540.10 166 233 3.6E-10 T 29-03-2018 THSYN_RS18045 78384543029685ce802dbe12a5ffcdd8 290 Gene3D G3DSA:1.10.3540.10 8 140 5.3E-17 T 29-03-2018 THSYN_RS26000 fe2e4c5b2d551808fcd093090f5882cc 293 Hamap MF_00117 33 kDa chaperonin [hslO]. 4 283 30.395 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 THSYN_RS26000 fe2e4c5b2d551808fcd093090f5882cc 293 Gene3D G3DSA:3.90.1280.10 225 280 2.5E-21 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 THSYN_RS26000 fe2e4c5b2d551808fcd093090f5882cc 293 Gene3D G3DSA:3.55.30.10 1 172 7.3E-59 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 THSYN_RS26000 fe2e4c5b2d551808fcd093090f5882cc 293 SUPERFAMILY SSF64397 5 231 6.8E-68 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 THSYN_RS26000 fe2e4c5b2d551808fcd093090f5882cc 293 Gene3D G3DSA:1.10.287.480 180 224 1.2E-18 T 29-03-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain THSYN_RS26000 fe2e4c5b2d551808fcd093090f5882cc 293 PIRSF PIRSF005261 1 283 9.1E-78 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 THSYN_RS26000 fe2e4c5b2d551808fcd093090f5882cc 293 Pfam PF01430 Hsp33 protein 5 272 1.6E-86 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 THSYN_RS26000 fe2e4c5b2d551808fcd093090f5882cc 293 SUPERFAMILY SSF118352 224 281 1.11E-18 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 THSYN_RS12390 25def29c88da0dc04bc810967fc93db1 691 Gene3D G3DSA:2.130.10.10 152 660 3.3E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS12390 25def29c88da0dc04bc810967fc93db1 691 Pfam PF05787 Bacterial protein of unknown function (DUF839) 222 662 1.0E-16 T 29-03-2018 IPR008557 Protein of unknown function DUF839 THSYN_RS16505 457b45f406f0b7e9b3cfc326d5988a5f 157 Gene3D G3DSA:3.30.70.20 2 31 0.013 T 29-03-2018 THSYN_RS16505 457b45f406f0b7e9b3cfc326d5988a5f 157 Gene3D G3DSA:3.30.70.20 32 62 9.5E-8 T 29-03-2018 THSYN_RS16505 457b45f406f0b7e9b3cfc326d5988a5f 157 Gene3D G3DSA:3.30.70.20 63 143 3.9E-4 T 29-03-2018 THSYN_RS16505 457b45f406f0b7e9b3cfc326d5988a5f 157 Pfam PF13187 4Fe-4S dicluster domain 9 68 3.3E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS16505 457b45f406f0b7e9b3cfc326d5988a5f 157 SUPERFAMILY SSF54862 3 114 6.37E-22 T 29-03-2018 THSYN_RS16505 457b45f406f0b7e9b3cfc326d5988a5f 157 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 53 64 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS16505 457b45f406f0b7e9b3cfc326d5988a5f 157 TIGRFAM TIGR02060 aprB: adenylylsulfate reductase, beta subunit 1 128 1.9E-58 T 29-03-2018 IPR011802 Adenylylsulphate reductase, beta subunit THSYN_RS16505 457b45f406f0b7e9b3cfc326d5988a5f 157 Pfam PF12139 Adenosine-5'-phosphosulfate reductase beta subunit 70 140 5.0E-27 T 29-03-2018 IPR022738 Adenylylsulphate reductase, beta subunit, C-terminal THSYN_RS03750 e95668e0f054b0dbd483b89a97ebbb70 408 Gene3D G3DSA:3.60.40.10 133 397 2.1E-24 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS03750 e95668e0f054b0dbd483b89a97ebbb70 408 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 201 394 7.6E-25 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS03750 e95668e0f054b0dbd483b89a97ebbb70 408 SUPERFAMILY SSF81606 183 392 8.37E-8 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS03750 e95668e0f054b0dbd483b89a97ebbb70 408 SMART SM00331 170 396 8.0E-14 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS02085 fd2171ee3d3a95774b2e4637ae462cb9 339 Pfam PF01380 SIS domain 55 187 7.7E-33 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 THSYN_RS02085 fd2171ee3d3a95774b2e4637ae462cb9 339 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 60 329 3.6E-106 T 29-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 THSYN_RS02085 fd2171ee3d3a95774b2e4637ae462cb9 339 Gene3D G3DSA:3.40.50.10490 17 213 1.1E-54 T 29-03-2018 THSYN_RS02085 fd2171ee3d3a95774b2e4637ae462cb9 339 SMART SM00116 225 273 0.27 T 29-03-2018 IPR000644 CBS domain THSYN_RS02085 fd2171ee3d3a95774b2e4637ae462cb9 339 SMART SM00116 290 338 12.0 T 29-03-2018 IPR000644 CBS domain THSYN_RS02085 fd2171ee3d3a95774b2e4637ae462cb9 339 SUPERFAMILY SSF53697 28 337 6.01E-67 T 29-03-2018 THSYN_RS02085 fd2171ee3d3a95774b2e4637ae462cb9 339 PIRSF PIRSF004692 10 339 3.5E-127 T 29-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 THSYN_RS02085 fd2171ee3d3a95774b2e4637ae462cb9 339 Pfam PF00571 CBS domain 286 336 3.7E-6 T 29-03-2018 IPR000644 CBS domain THSYN_RS02085 fd2171ee3d3a95774b2e4637ae462cb9 339 Pfam PF00571 CBS domain 216 273 7.6E-7 T 29-03-2018 IPR000644 CBS domain THSYN_RS02085 fd2171ee3d3a95774b2e4637ae462cb9 339 Gene3D G3DSA:3.10.580.10 214 337 2.5E-20 T 29-03-2018 THSYN_RS31605 08b9724982557af6b33b8e00e6b045a5 457 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 143 226 4.2E-20 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS31605 08b9724982557af6b33b8e00e6b045a5 457 SUPERFAMILY SSF56349 150 442 4.41E-51 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS31605 08b9724982557af6b33b8e00e6b045a5 457 Gene3D G3DSA:1.10.150.130 141 227 1.2E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS31605 08b9724982557af6b33b8e00e6b045a5 457 TIGRFAM TIGR02249 integrase_gron: integron integrase 144 456 5.0E-130 T 29-03-2018 IPR011946 Integrase, integron-type GO:0003677|GO:0006310|GO:0015074 THSYN_RS31605 08b9724982557af6b33b8e00e6b045a5 457 Gene3D G3DSA:1.10.150.130 15 94 0.02 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS31605 08b9724982557af6b33b8e00e6b045a5 457 Pfam PF00589 Phage integrase family 242 442 7.7E-44 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS31605 08b9724982557af6b33b8e00e6b045a5 457 Gene3D G3DSA:1.10.443.10 238 445 5.8E-49 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS14355 fa9e0c3419baa1528323909de51aa97d 336 Gene3D G3DSA:3.30.420.10 106 321 1.4E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS00120 0ee4623a679e313cc4ea355cdcdcc4fd 156 Pfam PF02556 Preprotein translocase subunit SecB 9 145 2.1E-56 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS00120 0ee4623a679e313cc4ea355cdcdcc4fd 156 Gene3D G3DSA:3.10.420.10 3 155 7.4E-52 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS00120 0ee4623a679e313cc4ea355cdcdcc4fd 156 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 8 144 1.7E-51 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS00120 0ee4623a679e313cc4ea355cdcdcc4fd 156 SUPERFAMILY SSF54611 4 144 2.09E-50 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS00120 0ee4623a679e313cc4ea355cdcdcc4fd 156 Hamap MF_00821 Protein-export protein SecB [secB]. 1 147 32.98 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS00120 0ee4623a679e313cc4ea355cdcdcc4fd 156 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 15 32 9.4E-35 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS00120 0ee4623a679e313cc4ea355cdcdcc4fd 156 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 75 95 9.4E-35 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS00120 0ee4623a679e313cc4ea355cdcdcc4fd 156 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 99 121 9.4E-35 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS00120 0ee4623a679e313cc4ea355cdcdcc4fd 156 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 125 143 9.4E-35 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS18500 24a31b5ce84de6ee8a96199df228871b 463 PIRSF PIRSF034888 1 85 3.9E-12 T 29-03-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 THSYN_RS18500 24a31b5ce84de6ee8a96199df228871b 463 PIRSF PIRSF034888 187 454 7.1E-32 T 29-03-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 THSYN_RS18500 24a31b5ce84de6ee8a96199df228871b 463 Pfam PF13175 AAA ATPase domain 282 386 2.3E-12 T 29-03-2018 THSYN_RS18500 24a31b5ce84de6ee8a96199df228871b 463 SUPERFAMILY SSF52540 289 393 7.4E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS18500 24a31b5ce84de6ee8a96199df228871b 463 SUPERFAMILY SSF52540 2 119 7.4E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS18500 24a31b5ce84de6ee8a96199df228871b 463 Pfam PF12476 Protein of unknown function (DUF3696) 398 443 7.3E-10 T 29-03-2018 IPR022532 Domain of unknown function DUF3696, C-terminal THSYN_RS18500 24a31b5ce84de6ee8a96199df228871b 463 Gene3D G3DSA:3.40.50.300 19 396 6.4E-12 T 29-03-2018 THSYN_RS23945 0ee9f0299389007eb519e4f7516ff448 110 Gene3D G3DSA:2.30.30.110 1 110 9.5E-11 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS23945 0ee9f0299389007eb519e4f7516ff448 110 SUPERFAMILY SSF50118 3 107 6.54E-13 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS23945 0ee9f0299389007eb519e4f7516ff448 110 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 104 3.5E-9 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS06255 06a36c9edfa579dcdde8af1226869dff 812 Pfam PF07503 HypF finger 161 192 1.1E-16 T 29-03-2018 IPR011125 Zinc finger, HypF-type GO:0008270 THSYN_RS06255 06a36c9edfa579dcdde8af1226869dff 812 Pfam PF07503 HypF finger 110 143 2.3E-15 T 29-03-2018 IPR011125 Zinc finger, HypF-type GO:0008270 THSYN_RS06255 06a36c9edfa579dcdde8af1226869dff 812 Gene3D G3DSA:3.90.870.10 201 405 3.7E-58 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain THSYN_RS06255 06a36c9edfa579dcdde8af1226869dff 812 Gene3D G3DSA:3.30.70.100 1 100 1.9E-20 T 29-03-2018 THSYN_RS06255 06a36c9edfa579dcdde8af1226869dff 812 SUPERFAMILY SSF54975 4 83 1.16E-18 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THSYN_RS06255 06a36c9edfa579dcdde8af1226869dff 812 Gene3D G3DSA:3.30.420.40 608 776 2.2E-30 T 29-03-2018 THSYN_RS06255 06a36c9edfa579dcdde8af1226869dff 812 Pfam PF01300 Telomere recombination 217 398 1.4E-49 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 THSYN_RS06255 06a36c9edfa579dcdde8af1226869dff 812 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 5 797 1.6E-230 T 29-03-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 THSYN_RS06255 06a36c9edfa579dcdde8af1226869dff 812 Pfam PF00708 Acylphosphatase 4 82 8.2E-15 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THSYN_RS06255 06a36c9edfa579dcdde8af1226869dff 812 PIRSF PIRSF006256 1 804 2.7E-284 T 29-03-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 THSYN_RS06255 06a36c9edfa579dcdde8af1226869dff 812 SUPERFAMILY SSF55821 178 411 1.86E-50 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain THSYN_RS06255 06a36c9edfa579dcdde8af1226869dff 812 ProSitePatterns PS00150 Acylphosphatase signature 1. 7 17 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THSYN_RS20245 8e03440a90c0ab7321920bf01ac2061c 310 Pfam PF12784 PD-(D/E)XK nuclease family transposase 7 229 9.0E-52 T 29-03-2018 THSYN_RS20245 8e03440a90c0ab7321920bf01ac2061c 310 Gene3D G3DSA:1.20.1600.10 68 300 1.0E-4 T 29-03-2018 THSYN_RS20245 8e03440a90c0ab7321920bf01ac2061c 310 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 8 243 2.0E-29 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA THSYN_RS13235 81ead4d6a8ca9bd5f6764aacba982918 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 91 189 6.4E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS13235 81ead4d6a8ca9bd5f6764aacba982918 222 Gene3D G3DSA:3.40.50.1000 7 217 1.1E-24 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS13235 81ead4d6a8ca9bd5f6764aacba982918 222 SUPERFAMILY SSF56784 5 216 1.29E-39 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS13235 81ead4d6a8ca9bd5f6764aacba982918 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 188 1.1E-10 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS03240 6b4f5c85a543b6f03319d5018edca885 1555 Gene3D G3DSA:3.20.20.70 449 798 6.2E-86 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS03240 6b4f5c85a543b6f03319d5018edca885 1555 Gene3D G3DSA:3.20.20.70 799 1238 7.4E-163 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS03240 6b4f5c85a543b6f03319d5018edca885 1555 Gene3D G3DSA:3.60.20.10 22 448 6.5E-169 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS03240 6b4f5c85a543b6f03319d5018edca885 1555 SUPERFAMILY SSF56235 22 443 4.71E-159 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS03240 6b4f5c85a543b6f03319d5018edca885 1555 SUPERFAMILY SSF69336 1235 1452 1.31E-93 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THSYN_RS03240 6b4f5c85a543b6f03319d5018edca885 1555 SUPERFAMILY SSF69336 1481 1528 1.31E-93 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THSYN_RS03240 6b4f5c85a543b6f03319d5018edca885 1555 SUPERFAMILY SSF51395 455 1223 4.58E-264 T 29-03-2018 THSYN_RS03240 6b4f5c85a543b6f03319d5018edca885 1555 Pfam PF04898 Glutamate synthase central domain 468 754 3.5E-111 T 29-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 THSYN_RS03240 6b4f5c85a543b6f03319d5018edca885 1555 Pfam PF01645 Conserved region in glutamate synthase 817 1186 4.1E-157 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 THSYN_RS03240 6b4f5c85a543b6f03319d5018edca885 1555 Pfam PF01493 GXGXG motif 1266 1452 1.9E-81 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THSYN_RS03240 6b4f5c85a543b6f03319d5018edca885 1555 Gene3D G3DSA:2.160.20.60 1241 1542 7.1E-115 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THSYN_RS03240 6b4f5c85a543b6f03319d5018edca885 1555 Pfam PF00310 Glutamine amidotransferases class-II 22 440 1.1E-188 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain THSYN_RS26145 9f03cd26c41e36a8f52947608c0bd0e0 207 SUPERFAMILY SSF53335 27 205 5.41E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS26145 9f03cd26c41e36a8f52947608c0bd0e0 207 Pfam PF01728 FtsJ-like methyltransferase 28 204 1.6E-57 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 THSYN_RS26145 9f03cd26c41e36a8f52947608c0bd0e0 207 Gene3D G3DSA:3.40.50.150 1 207 9.6E-63 T 29-03-2018 THSYN_RS26145 9f03cd26c41e36a8f52947608c0bd0e0 207 PIRSF PIRSF005461 1 207 4.3E-76 T 29-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 THSYN_RS26145 9f03cd26c41e36a8f52947608c0bd0e0 207 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 12 205 30.675 T 29-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 THSYN_RS28355 b9bb25d25362183264f3f7fcf31a278c 361 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 170 195 - T 29-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 THSYN_RS28355 b9bb25d25362183264f3f7fcf31a278c 361 SUPERFAMILY SSF52283 1 168 1.02E-47 T 29-03-2018 THSYN_RS28355 b9bb25d25362183264f3f7fcf31a278c 361 Gene3D G3DSA:3.40.50.720 195 361 1.4E-34 T 29-03-2018 THSYN_RS28355 b9bb25d25362183264f3f7fcf31a278c 361 SUPERFAMILY SSF51735 137 316 1.25E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS28355 b9bb25d25362183264f3f7fcf31a278c 361 Gene3D G3DSA:3.40.50.720 1 170 7.0E-44 T 29-03-2018 THSYN_RS28355 b9bb25d25362183264f3f7fcf31a278c 361 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 1.1E-38 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal THSYN_RS28355 b9bb25d25362183264f3f7fcf31a278c 361 SMART SM01002 146 310 1.9E-73 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain THSYN_RS28355 b9bb25d25362183264f3f7fcf31a278c 361 SMART SM01003 4 137 1.4E-54 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal THSYN_RS28355 b9bb25d25362183264f3f7fcf31a278c 361 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 341 3.9E-59 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain THSYN_RS30585 30e32ed44571a3930770c0b66b54de01 327 Gene3D G3DSA:3.90.180.10 2 156 1.6E-18 T 29-03-2018 THSYN_RS30585 30e32ed44571a3930770c0b66b54de01 327 SUPERFAMILY SSF50129 8 158 5.94E-17 T 29-03-2018 IPR011032 GroES-like THSYN_RS30585 30e32ed44571a3930770c0b66b54de01 327 Gene3D G3DSA:3.40.50.720 157 265 2.9E-10 T 29-03-2018 THSYN_RS30585 30e32ed44571a3930770c0b66b54de01 327 SUPERFAMILY SSF51735 128 268 4.43E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 Gene3D G3DSA:1.10.287.40 2 104 8.7E-21 T 29-03-2018 THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 SUPERFAMILY SSF55681 116 420 1.38E-96 T 29-03-2018 THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 PIRSF PIRSF001529 1 424 1.4E-164 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 1.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 1.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 1.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 1.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 1.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 220 400 4.4E-29 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 Gene3D G3DSA:3.30.930.10 105 424 1.3E-94 T 29-03-2018 THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 SUPERFAMILY SSF46589 2 112 2.72E-24 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 3.4E-24 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 39.692 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THSYN_RS09190 a48e48bf1024b1ac00a8358e6d73528b 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 417 4.0E-160 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THSYN_RS19045 52ca7457f4d065a1a939ce1d5b5dfd7c 576 Gene3D G3DSA:1.10.645.10 1 561 5.3E-197 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS19045 52ca7457f4d065a1a939ce1d5b5dfd7c 576 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 552 561 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THSYN_RS19045 52ca7457f4d065a1a939ce1d5b5dfd7c 576 Pfam PF00374 Nickel-dependent hydrogenase 39 561 2.6E-230 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THSYN_RS19045 52ca7457f4d065a1a939ce1d5b5dfd7c 576 SUPERFAMILY SSF56762 1 561 1.57E-172 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS19045 52ca7457f4d065a1a939ce1d5b5dfd7c 576 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 39 64 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THSYN_RS26505 1355c6cdd132422cfad3dc07224d15cf 441 Pfam PF04403 Paraquat-inducible protein A 302 386 1.1E-8 T 29-03-2018 IPR007498 Paraquat-inducible protein A THSYN_RS31815 0aa56c488e4234d11b5a134fae719e18 400 Gene3D G3DSA:3.50.50.60 2 155 1.8E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31815 0aa56c488e4234d11b5a134fae719e18 400 SUPERFAMILY SSF51905 256 364 1.48E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31815 0aa56c488e4234d11b5a134fae719e18 400 SUPERFAMILY SSF51905 7 168 1.48E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31815 0aa56c488e4234d11b5a134fae719e18 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 270 285 2.0E-15 T 29-03-2018 THSYN_RS31815 0aa56c488e4234d11b5a134fae719e18 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 2.0E-15 T 29-03-2018 THSYN_RS31815 0aa56c488e4234d11b5a134fae719e18 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 2.0E-15 T 29-03-2018 THSYN_RS31815 0aa56c488e4234d11b5a134fae719e18 400 Gene3D G3DSA:3.30.9.10 156 330 3.9E-34 T 29-03-2018 THSYN_RS31815 0aa56c488e4234d11b5a134fae719e18 400 TIGRFAM TIGR02023 BchP-ChlP: geranylgeranyl reductase 8 394 4.3E-150 T 29-03-2018 IPR010253 Geranylgeranyl reductase, plant/prokaryotic GO:0015979|GO:0015995|GO:0045550|GO:0055114 KEGG: 00900+1.3.1.83 THSYN_RS31815 0aa56c488e4234d11b5a134fae719e18 400 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 8 305 7.9E-78 T 29-03-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 THSYN_RS31815 0aa56c488e4234d11b5a134fae719e18 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 169 3.6E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS26820 affd7c4fd7037cade6363db4e51165b9 408 Pfam PF13489 Methyltransferase domain 82 237 3.5E-15 T 29-03-2018 THSYN_RS26820 affd7c4fd7037cade6363db4e51165b9 408 Pfam PF08421 Putative zinc binding domain 3 64 3.4E-21 T 29-03-2018 IPR013630 Methyltransferase putative zinc binding domain THSYN_RS26820 affd7c4fd7037cade6363db4e51165b9 408 Gene3D G3DSA:3.40.50.150 55 256 2.2E-30 T 29-03-2018 THSYN_RS26820 affd7c4fd7037cade6363db4e51165b9 408 SUPERFAMILY SSF53335 63 249 2.09E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS26820 affd7c4fd7037cade6363db4e51165b9 408 Pfam PF08484 C-methyltransferase C-terminal domain 244 403 2.8E-64 T 29-03-2018 IPR013691 C-methyltransferase THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 SMART SM00028 481 514 44.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 SMART SM00028 447 480 0.0064 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 SMART SM00028 304 337 160.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 SMART SM00220 16 276 2.2E-26 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 Gene3D G3DSA:1.25.40.10 319 407 5.1E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 Gene3D G3DSA:1.25.40.10 462 524 2.0E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 SUPERFAMILY SSF48452 391 511 1.12E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 48 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 Pfam PF13432 Tetratricopeptide repeat 390 446 0.0066 T 29-03-2018 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 Gene3D G3DSA:3.30.200.20 7 97 7.1E-14 T 29-03-2018 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 Pfam PF00069 Protein kinase domain 17 267 9.4E-31 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 SUPERFAMILY SSF56112 9 302 2.43E-53 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 Gene3D G3DSA:1.10.510.10 98 318 8.3E-33 T 29-03-2018 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 141 153 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 SUPERFAMILY SSF48452 304 433 1.27E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16030 84dcfb3ad5cd80a3bccc06c1ff7575df 526 Gene3D G3DSA:1.25.40.10 408 461 1.0E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS31645 078d68374c901d891e37778a8e9aa454 553 Gene3D G3DSA:3.40.50.280 13 136 5.6E-17 T 29-03-2018 THSYN_RS31645 078d68374c901d891e37778a8e9aa454 553 TIGRFAM TIGR02026 BchE: magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase 2 499 2.9E-246 T 29-03-2018 IPR011772 Magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase GO:0015995|GO:0016709|GO:0050661|GO:0055114 THSYN_RS31645 078d68374c901d891e37778a8e9aa454 553 Pfam PF02310 B12 binding domain 11 132 4.0E-24 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 THSYN_RS31645 078d68374c901d891e37778a8e9aa454 553 SMART SM00729 195 408 3.3E-29 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS31645 078d68374c901d891e37778a8e9aa454 553 SUPERFAMILY SSF102114 184 391 6.02E-38 T 29-03-2018 THSYN_RS31645 078d68374c901d891e37778a8e9aa454 553 Pfam PF04055 Radical SAM superfamily 201 362 5.2E-20 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS31645 078d68374c901d891e37778a8e9aa454 553 Gene3D G3DSA:3.20.20.70 193 499 4.5E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS31490 b2fbc1776876aacd3cf6db26cfbdcc17 287 SUPERFAMILY SSF52540 61 250 1.69E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31490 b2fbc1776876aacd3cf6db26cfbdcc17 287 Gene3D G3DSA:3.40.50.300 13 278 1.8E-76 T 29-03-2018 THSYN_RS31490 b2fbc1776876aacd3cf6db26cfbdcc17 287 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 5 266 1.0E-106 T 29-03-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 THSYN_RS31490 b2fbc1776876aacd3cf6db26cfbdcc17 287 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 31 255 4.0E-68 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related THSYN_RS31490 b2fbc1776876aacd3cf6db26cfbdcc17 287 PIRSF PIRSF028756 3 284 8.8E-72 T 29-03-2018 IPR016898 Polyphosphate kinase 2 THSYN_RS25040 2b3acfadb3dee9147e78c5713bc80bea 258 Pfam PF02698 DUF218 domain 83 248 2.6E-34 T 29-03-2018 IPR003848 Domain of unknown function DUF218 THSYN_RS25040 2b3acfadb3dee9147e78c5713bc80bea 258 Gene3D G3DSA:3.40.50.620 71 222 1.5E-39 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS04405 4d84b15173222fd72342c7ce9b82f99a 161 SUPERFAMILY SSF46785 22 75 7.72E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS04405 4d84b15173222fd72342c7ce9b82f99a 161 Pfam PF08279 HTH domain 21 60 7.4E-5 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 THSYN_RS04405 4d84b15173222fd72342c7ce9b82f99a 161 Gene3D G3DSA:1.10.10.10 5 78 7.6E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS14460 8abf9dcf6e405bae78ad0dd00e12349e 1134 Gene3D G3DSA:2.60.120.260 36 209 3.9E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS14460 8abf9dcf6e405bae78ad0dd00e12349e 1134 Gene3D G3DSA:2.60.120.430 398 586 2.3E-13 T 29-03-2018 THSYN_RS14460 8abf9dcf6e405bae78ad0dd00e12349e 1134 Gene3D G3DSA:2.60.120.430 271 394 6.1E-8 T 29-03-2018 THSYN_RS14460 8abf9dcf6e405bae78ad0dd00e12349e 1134 SUPERFAMILY SSF49785 410 510 8.5E-14 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS14460 8abf9dcf6e405bae78ad0dd00e12349e 1134 SUPERFAMILY SSF49785 540 580 8.5E-14 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS17920 dfd4fb68b5759ae68bbeb4e62c4b9d58 437 Gene3D G3DSA:3.30.70.1050 1 118 4.1E-30 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 THSYN_RS17920 dfd4fb68b5759ae68bbeb4e62c4b9d58 437 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 265 411 2.0E-27 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 THSYN_RS17920 dfd4fb68b5759ae68bbeb4e62c4b9d58 437 SUPERFAMILY SSF109998 250 427 2.75E-38 T 29-03-2018 IPR027304 Trigger factor/SurA domain THSYN_RS17920 dfd4fb68b5759ae68bbeb4e62c4b9d58 437 SUPERFAMILY SSF54534 90 242 6.68E-25 T 29-03-2018 THSYN_RS17920 dfd4fb68b5759ae68bbeb4e62c4b9d58 437 Gene3D G3DSA:1.10.3120.10 213 388 1.7E-33 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 THSYN_RS17920 dfd4fb68b5759ae68bbeb4e62c4b9d58 437 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 5.3E-34 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 THSYN_RS17920 dfd4fb68b5759ae68bbeb4e62c4b9d58 437 Hamap MF_00303 Trigger factor [tig]. 1 417 19.069 T 29-03-2018 IPR005215 Trigger factor GO:0015031 THSYN_RS17920 dfd4fb68b5759ae68bbeb4e62c4b9d58 437 SUPERFAMILY SSF102735 1 130 1.44E-31 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 THSYN_RS17920 dfd4fb68b5759ae68bbeb4e62c4b9d58 437 PIRSF PIRSF003095 1 431 3.1E-106 T 29-03-2018 IPR005215 Trigger factor GO:0015031 THSYN_RS17920 dfd4fb68b5759ae68bbeb4e62c4b9d58 437 TIGRFAM TIGR00115 tig: trigger factor 11 411 1.5E-113 T 29-03-2018 IPR005215 Trigger factor GO:0015031 THSYN_RS17920 dfd4fb68b5759ae68bbeb4e62c4b9d58 437 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 157 230 3.0E-10 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain THSYN_RS09920 99a923ecb907fd53ffc10f48645cae6a 1016 Pfam PF00754 F5/8 type C domain 173 267 1.7E-9 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain THSYN_RS09920 99a923ecb907fd53ffc10f48645cae6a 1016 SUPERFAMILY SSF49785 173 268 5.8E-10 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS09920 99a923ecb907fd53ffc10f48645cae6a 1016 Gene3D G3DSA:2.60.120.430 1 162 7.8E-11 T 29-03-2018 THSYN_RS09920 99a923ecb907fd53ffc10f48645cae6a 1016 Gene3D G3DSA:1.50.10.10 518 922 6.6E-28 T 29-03-2018 THSYN_RS09920 99a923ecb907fd53ffc10f48645cae6a 1016 Gene3D G3DSA:2.60.120.260 163 286 8.4E-14 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS09920 99a923ecb907fd53ffc10f48645cae6a 1016 SUPERFAMILY SSF48208 550 971 8.08E-33 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 THSYN_RS03325 d9f985978444df64105eda1f856bbdf4 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 169 184 3.6E-5 T 29-03-2018 THSYN_RS03325 d9f985978444df64105eda1f856bbdf4 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 3.6E-5 T 29-03-2018 THSYN_RS03325 d9f985978444df64105eda1f856bbdf4 376 Gene3D G3DSA:3.30.9.10 158 301 1.8E-34 T 29-03-2018 THSYN_RS03325 d9f985978444df64105eda1f856bbdf4 376 SUPERFAMILY SSF54373 216 303 1.1E-16 T 29-03-2018 THSYN_RS03325 d9f985978444df64105eda1f856bbdf4 376 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 4 346 1.7E-78 T 29-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 THSYN_RS03325 d9f985978444df64105eda1f856bbdf4 376 Pfam PF01266 FAD dependent oxidoreductase 3 342 2.6E-65 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THSYN_RS03325 d9f985978444df64105eda1f856bbdf4 376 SUPERFAMILY SSF51905 303 358 1.55E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03325 d9f985978444df64105eda1f856bbdf4 376 SUPERFAMILY SSF51905 2 216 1.55E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03325 d9f985978444df64105eda1f856bbdf4 376 Gene3D G3DSA:3.30.9.10 96 157 0.25 T 29-03-2018 THSYN_RS03325 d9f985978444df64105eda1f856bbdf4 376 Gene3D G3DSA:3.40.50.720 1 93 4.3E-6 T 29-03-2018 THSYN_RS26990 a976b47da757dc1695af10dcf438a608 89 Pfam PF03683 Uncharacterised protein family (UPF0175) 8 80 1.4E-24 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS04755 aa4d2934e2deba05baed7f9b64188cbc 749 Gene3D G3DSA:1.10.268.10 348 487 1.1E-41 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS04755 aa4d2934e2deba05baed7f9b64188cbc 749 Gene3D G3DSA:2.120.10.90 499 747 1.0E-40 T 29-03-2018 THSYN_RS04755 aa4d2934e2deba05baed7f9b64188cbc 749 SUPERFAMILY SSF56719 35 487 9.16E-154 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THSYN_RS04755 aa4d2934e2deba05baed7f9b64188cbc 749 SMART SM00434 15 465 1.5E-225 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS04755 aa4d2934e2deba05baed7f9b64188cbc 749 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 470 4.0E-133 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS04755 aa4d2934e2deba05baed7f9b64188cbc 749 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 8 747 34.183 T 29-03-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS04755 aa4d2934e2deba05baed7f9b64188cbc 749 Gene3D G3DSA:3.90.199.10 38 287 1.5E-100 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS04755 aa4d2934e2deba05baed7f9b64188cbc 749 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 653 700 1.1E-4 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THSYN_RS04755 aa4d2934e2deba05baed7f9b64188cbc 749 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 601 637 1.2 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THSYN_RS04755 aa4d2934e2deba05baed7f9b64188cbc 749 SUPERFAMILY SSF101904 505 747 3.4E-50 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal THSYN_RS04755 aa4d2934e2deba05baed7f9b64188cbc 749 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 13 744 0.0 T 29-03-2018 THSYN_RS31000 50e2d3703e92991c311bcbf5f32111f8 294 PRINTS PR00116 Arginase signature 104 119 2.3E-13 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 THSYN_RS31000 50e2d3703e92991c311bcbf5f32111f8 294 PRINTS PR00116 Arginase signature 216 245 2.3E-13 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 THSYN_RS31000 50e2d3703e92991c311bcbf5f32111f8 294 ProSitePatterns PS01053 Arginase family signature. 219 240 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 THSYN_RS31000 50e2d3703e92991c311bcbf5f32111f8 294 Gene3D G3DSA:3.40.800.10 1 291 3.5E-82 T 29-03-2018 THSYN_RS31000 50e2d3703e92991c311bcbf5f32111f8 294 TIGRFAM TIGR01230 agmatinase: agmatinase 11 288 2.8E-53 T 29-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 THSYN_RS31000 50e2d3703e92991c311bcbf5f32111f8 294 SUPERFAMILY SSF52768 16 291 1.37E-79 T 29-03-2018 THSYN_RS31000 50e2d3703e92991c311bcbf5f32111f8 294 PIRSF PIRSF036979 1 293 4.0E-78 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 THSYN_RS31000 50e2d3703e92991c311bcbf5f32111f8 294 Pfam PF00491 Arginase family 22 287 7.3E-77 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 THSYN_RS11290 35e06fd9d4283bf4ff39c3be421b27bf 653 SUPERFAMILY SSF53955 489 638 8.13E-42 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS11290 35e06fd9d4283bf4ff39c3be421b27bf 653 Gene3D G3DSA:1.25.20.10 33 396 4.5E-47 T 29-03-2018 THSYN_RS11290 35e06fd9d4283bf4ff39c3be421b27bf 653 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 510 538 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 THSYN_RS11290 35e06fd9d4283bf4ff39c3be421b27bf 653 Gene3D G3DSA:1.10.1240.20 413 481 2.0E-20 T 29-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 THSYN_RS11290 35e06fd9d4283bf4ff39c3be421b27bf 653 Pfam PF01464 Transglycosylase SLT domain 492 598 7.4E-24 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 THSYN_RS11290 35e06fd9d4283bf4ff39c3be421b27bf 653 SUPERFAMILY SSF48435 33 486 5.36E-102 T 29-03-2018 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 THSYN_RS11290 35e06fd9d4283bf4ff39c3be421b27bf 653 Gene3D G3DSA:1.10.530.10 482 643 2.4E-36 T 29-03-2018 THSYN_RS11290 35e06fd9d4283bf4ff39c3be421b27bf 653 Pfam PF14718 Soluble lytic murein transglycosylase L domain 416 481 1.2E-19 T 29-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 THSYN_RS25905 48836ed2fa9cbcdfe9ddb5ef2154e23a 163 SUPERFAMILY SSF55021 79 161 7.78E-26 T 29-03-2018 THSYN_RS25905 48836ed2fa9cbcdfe9ddb5ef2154e23a 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 8.3E-27 T 29-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 THSYN_RS25905 48836ed2fa9cbcdfe9ddb5ef2154e23a 163 SUPERFAMILY SSF55021 1 74 1.05E-21 T 29-03-2018 THSYN_RS25905 48836ed2fa9cbcdfe9ddb5ef2154e23a 163 Gene3D G3DSA:3.30.70.260 1 87 2.1E-23 T 29-03-2018 THSYN_RS25905 48836ed2fa9cbcdfe9ddb5ef2154e23a 163 Gene3D G3DSA:3.30.70.1150 88 160 2.4E-27 T 29-03-2018 THSYN_RS25905 48836ed2fa9cbcdfe9ddb5ef2154e23a 163 Pfam PF13710 ACT domain 13 71 7.3E-15 T 29-03-2018 THSYN_RS25905 48836ed2fa9cbcdfe9ddb5ef2154e23a 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 2.0E-32 T 29-03-2018 THSYN_RS25905 48836ed2fa9cbcdfe9ddb5ef2154e23a 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 158 6.8E-65 T 29-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 THSYN_RS27655 1bfb42e0b58c66bda20718525606912d 204 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 10 177 2.1E-44 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 THSYN_RS27655 1bfb42e0b58c66bda20718525606912d 204 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 5 187 30.593 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 THSYN_RS27655 1bfb42e0b58c66bda20718525606912d 204 Gene3D G3DSA:2.170.120.20 101 193 1.0E-28 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain THSYN_RS27655 1bfb42e0b58c66bda20718525606912d 204 SUPERFAMILY SSF50715 6 195 3.49E-55 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THSYN_RS27655 1bfb42e0b58c66bda20718525606912d 204 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 9 97 2.0E-23 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 THSYN_RS27655 1bfb42e0b58c66bda20718525606912d 204 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 5 97 22.926 T 29-03-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 THSYN_RS27655 1bfb42e0b58c66bda20718525606912d 204 Pfam PF01386 Ribosomal L25p family 9 94 2.4E-26 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 THSYN_RS27655 1bfb42e0b58c66bda20718525606912d 204 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 102 187 1.7E-28 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain THSYN_RS27655 1bfb42e0b58c66bda20718525606912d 204 Gene3D G3DSA:2.40.240.10 4 97 2.7E-30 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THSYN_RS11305 33ce935b4fa9c395ee63a6fb16db128d 622 SMART SM00052 367 614 4.0E-99 T 29-03-2018 IPR001633 EAL domain THSYN_RS11305 33ce935b4fa9c395ee63a6fb16db128d 622 SMART SM00267 185 357 2.2E-69 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS11305 33ce935b4fa9c395ee63a6fb16db128d 622 Gene3D G3DSA:3.20.20.450 365 618 4.1E-91 T 29-03-2018 IPR001633 EAL domain THSYN_RS11305 33ce935b4fa9c395ee63a6fb16db128d 622 Gene3D G3DSA:3.30.70.270 197 364 1.0E-65 T 29-03-2018 THSYN_RS11305 33ce935b4fa9c395ee63a6fb16db128d 622 Pfam PF00990 Diguanylate cyclase, GGDEF domain 196 352 3.2E-53 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS11305 33ce935b4fa9c395ee63a6fb16db128d 622 Pfam PF13188 PAS domain 63 120 2.8E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS11305 33ce935b4fa9c395ee63a6fb16db128d 622 Pfam PF00563 EAL domain 373 609 3.5E-67 T 29-03-2018 IPR001633 EAL domain THSYN_RS11305 33ce935b4fa9c395ee63a6fb16db128d 622 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 194 354 3.2E-45 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS11305 33ce935b4fa9c395ee63a6fb16db128d 622 SUPERFAMILY SSF55785 49 159 2.09E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS11305 33ce935b4fa9c395ee63a6fb16db128d 622 SUPERFAMILY SSF141868 373 620 6.41E-77 T 29-03-2018 IPR001633 EAL domain THSYN_RS11305 33ce935b4fa9c395ee63a6fb16db128d 622 Gene3D G3DSA:3.30.450.20 47 192 1.0E-17 T 29-03-2018 THSYN_RS11305 33ce935b4fa9c395ee63a6fb16db128d 622 SUPERFAMILY SSF55073 201 358 1.19E-54 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS11615 759740c6ac1e2a25c654ef8aeeb64917 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 7.6E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS11615 759740c6ac1e2a25c654ef8aeeb64917 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 7.6E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS11615 759740c6ac1e2a25c654ef8aeeb64917 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 223 7.6E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS11615 759740c6ac1e2a25c654ef8aeeb64917 268 Pfam PF00561 alpha/beta hydrolase fold 20 252 8.8E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS11615 759740c6ac1e2a25c654ef8aeeb64917 268 TIGRFAM TIGR01738 bioH: pimelyl-[acyl-carrier protein] methyl ester esterase 18 262 9.8E-70 T 29-03-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 THSYN_RS11615 759740c6ac1e2a25c654ef8aeeb64917 268 SUPERFAMILY SSF53474 16 265 8.51E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS11615 759740c6ac1e2a25c654ef8aeeb64917 268 Hamap MF_01260 Pimeloyl-[acyl-carrier protein] methyl ester esterase [bioH]. 3 264 37.088 T 29-03-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 THSYN_RS11615 759740c6ac1e2a25c654ef8aeeb64917 268 Gene3D G3DSA:3.40.50.1820 11 266 1.5E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS04360 64bd3095840697eac67819251797cf6f 120 SMART SM00448 1 111 1.5E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS04360 64bd3095840697eac67819251797cf6f 120 Pfam PF00072 Response regulator receiver domain 3 105 1.6E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS04360 64bd3095840697eac67819251797cf6f 120 SUPERFAMILY SSF52172 1 101 1.99E-23 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS04360 64bd3095840697eac67819251797cf6f 120 Gene3D G3DSA:3.40.50.2300 1 119 2.6E-22 T 29-03-2018 THSYN_RS31395 cc263b56daccff911446f6184cc8735d 49 SUPERFAMILY SSF56918 4 49 1.1E-18 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31395 cc263b56daccff911446f6184cc8735d 49 ProSitePatterns PS00969 Antenna complexes beta subunits signature. 16 47 - T 29-03-2018 IPR023623 Antenna complex, beta subunit, conserved site THSYN_RS31395 cc263b56daccff911446f6184cc8735d 49 Gene3D G3DSA:1.20.5.250 1 49 1.8E-26 T 29-03-2018 THSYN_RS31395 cc263b56daccff911446f6184cc8735d 49 Pfam PF00556 Antenna complex alpha/beta subunit 16 49 2.4E-12 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31395 cc263b56daccff911446f6184cc8735d 49 PRINTS PR00674 Light harvesting protein B chain signature 11 31 2.5E-13 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31395 cc263b56daccff911446f6184cc8735d 49 PRINTS PR00674 Light harvesting protein B chain signature 31 48 2.5E-13 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31395 cc263b56daccff911446f6184cc8735d 49 PIRSF PIRSF002900 1 49 1.1E-23 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS28425 bff129e654d61eb06927d6bad5e77589 301 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 25 301 44.952 T 29-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 THSYN_RS28425 bff129e654d61eb06927d6bad5e77589 301 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 67 299 6.7E-71 T 29-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 THSYN_RS28425 bff129e654d61eb06927d6bad5e77589 301 Pfam PF02666 Phosphatidylserine decarboxylase 78 298 1.3E-59 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 THSYN_RS10295 53c8d21bb659b0912946278fc7130848 308 Pfam PF01136 Peptidase family U32 119 271 4.5E-15 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 THSYN_RS04870 2a51b3283cf6650cb78f60750841b0fa 668 SUPERFAMILY SSF52518 343 533 7.23E-67 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS04870 2a51b3283cf6650cb78f60750841b0fa 668 Gene3D G3DSA:3.40.50.920 545 667 3.6E-32 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS04870 2a51b3283cf6650cb78f60750841b0fa 668 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS04870 2a51b3283cf6650cb78f60750841b0fa 668 ProSitePatterns PS00802 Transketolase signature 2. 474 490 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS04870 2a51b3283cf6650cb78f60750841b0fa 668 Pfam PF02780 Transketolase, C-terminal domain 547 660 7.6E-16 T 29-03-2018 IPR033248 Transketolase, C-terminal domain THSYN_RS04870 2a51b3283cf6650cb78f60750841b0fa 668 SUPERFAMILY SSF52518 5 335 3.48E-119 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS04870 2a51b3283cf6650cb78f60750841b0fa 668 Pfam PF02779 Transketolase, pyrimidine binding domain 360 532 7.5E-46 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THSYN_RS04870 2a51b3283cf6650cb78f60750841b0fa 668 Gene3D G3DSA:3.40.50.970 366 542 1.3E-45 T 29-03-2018 THSYN_RS04870 2a51b3283cf6650cb78f60750841b0fa 668 Gene3D G3DSA:3.40.50.970 1 365 5.1E-123 T 29-03-2018 THSYN_RS04870 2a51b3283cf6650cb78f60750841b0fa 668 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 340 3.7E-161 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS04870 2a51b3283cf6650cb78f60750841b0fa 668 SUPERFAMILY SSF52922 540 668 8.85E-43 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS04870 2a51b3283cf6650cb78f60750841b0fa 668 SMART SM00861 361 532 2.9E-67 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THSYN_RS04870 2a51b3283cf6650cb78f60750841b0fa 668 TIGRFAM TIGR00232 tktlase_bact: transketolase 6 667 3.4E-300 T 29-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 THSYN_RS01670 761c9ea4c446af83e0bb76300a433bc7 154 Pfam PF01047 MarR family 38 90 2.3E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THSYN_RS01670 761c9ea4c446af83e0bb76300a433bc7 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 1.2E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THSYN_RS01670 761c9ea4c446af83e0bb76300a433bc7 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 1.2E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THSYN_RS01670 761c9ea4c446af83e0bb76300a433bc7 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 1.2E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THSYN_RS01670 761c9ea4c446af83e0bb76300a433bc7 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 1.2E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THSYN_RS01670 761c9ea4c446af83e0bb76300a433bc7 154 Gene3D G3DSA:1.10.10.10 3 144 1.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS01670 761c9ea4c446af83e0bb76300a433bc7 154 SMART SM00347 26 126 2.5E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THSYN_RS01670 761c9ea4c446af83e0bb76300a433bc7 154 SUPERFAMILY SSF46785 6 140 1.19E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26895 12ee0c23f415b0d175b56a39dd36f135 108 Gene3D G3DSA:3.30.70.120 1 107 7.1E-27 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THSYN_RS26895 12ee0c23f415b0d175b56a39dd36f135 108 Pfam PF02641 Uncharacterized ACR, COG1993 6 84 2.8E-19 T 29-03-2018 IPR003793 Domain of unknown function DUF190 THSYN_RS26895 12ee0c23f415b0d175b56a39dd36f135 108 SUPERFAMILY SSF54913 1 101 9.12E-26 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THSYN_RS21845 202581d2545dec75f3e4c1f08cff1197 425 Gene3D G3DSA:3.90.1150.10 289 425 4.0E-50 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS21845 202581d2545dec75f3e4c1f08cff1197 425 PIRSF PIRSF001434 1 425 8.4E-133 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THSYN_RS21845 202581d2545dec75f3e4c1f08cff1197 425 Gene3D G3DSA:3.40.640.10 1 287 1.4E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS21845 202581d2545dec75f3e4c1f08cff1197 425 SUPERFAMILY SSF53383 1 422 2.79E-126 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS21845 202581d2545dec75f3e4c1f08cff1197 425 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 3 422 2.0E-199 T 29-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 THSYN_RS21845 202581d2545dec75f3e4c1f08cff1197 425 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 421 3.3E-144 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THSYN_RS21845 202581d2545dec75f3e4c1f08cff1197 425 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THSYN_RS33045 e6e748069503b9b3be96fdd73bb39931 289 SMART SM00382 58 233 3.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS33045 e6e748069503b9b3be96fdd73bb39931 289 Gene3D G3DSA:3.40.50.300 30 275 3.8E-50 T 29-03-2018 THSYN_RS33045 e6e748069503b9b3be96fdd73bb39931 289 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS33045 e6e748069503b9b3be96fdd73bb39931 289 Pfam PF00005 ABC transporter 49 183 1.1E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS33045 e6e748069503b9b3be96fdd73bb39931 289 SUPERFAMILY SSF52540 44 241 2.9E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03515 397cdf37e8d19959fe6c7d8ca087ed5b 151 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 151 46.389 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 THSYN_RS03515 397cdf37e8d19959fe6c7d8ca087ed5b 151 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 134 5.6E-40 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 THSYN_RS03515 397cdf37e8d19959fe6c7d8ca087ed5b 151 Gene3D G3DSA:2.10.260.10 79 129 8.5E-7 T 29-03-2018 THSYN_RS03515 397cdf37e8d19959fe6c7d8ca087ed5b 151 Gene3D G3DSA:2.10.260.10 4 46 0.053 T 29-03-2018 THSYN_RS03515 397cdf37e8d19959fe6c7d8ca087ed5b 151 SUPERFAMILY SSF89447 2 133 4.29E-41 T 29-03-2018 THSYN_RS03515 397cdf37e8d19959fe6c7d8ca087ed5b 151 Pfam PF02381 MraZ protein, putative antitoxin-like 2 74 3.9E-11 T 29-03-2018 IPR020603 MraZ domain THSYN_RS03515 397cdf37e8d19959fe6c7d8ca087ed5b 151 Pfam PF02381 MraZ protein, putative antitoxin-like 77 126 3.3E-16 T 29-03-2018 IPR020603 MraZ domain THSYN_RS03515 397cdf37e8d19959fe6c7d8ca087ed5b 151 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 125 3.0E-30 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 THSYN_RS03790 fb889c841febd833b40f4f80fd22be60 106 Pfam PF00699 Urease beta subunit 3 99 3.2E-45 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03790 fb889c841febd833b40f4f80fd22be60 106 Gene3D G3DSA:2.10.150.10 1 101 6.2E-46 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03790 fb889c841febd833b40f4f80fd22be60 106 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 32.374 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03790 fb889c841febd833b40f4f80fd22be60 106 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 102 3.0E-44 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS03790 fb889c841febd833b40f4f80fd22be60 106 SUPERFAMILY SSF51278 1 103 4.71E-48 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 THSYN_RS04135 94888afdad5ecd10c0b4fba6863504d6 425 Gene3D G3DSA:1.20.58.340 359 425 3.5E-20 T 29-03-2018 THSYN_RS04135 94888afdad5ecd10c0b4fba6863504d6 425 SUPERFAMILY SSF143865 95 360 2.22E-69 T 29-03-2018 THSYN_RS04135 94888afdad5ecd10c0b4fba6863504d6 425 Gene3D G3DSA:1.20.58.340 241 358 4.7E-32 T 29-03-2018 THSYN_RS04135 94888afdad5ecd10c0b4fba6863504d6 425 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 128 425 3.3E-78 T 29-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 THSYN_RS04135 94888afdad5ecd10c0b4fba6863504d6 425 SUPERFAMILY SSF144083 361 421 1.23E-18 T 29-03-2018 THSYN_RS04135 94888afdad5ecd10c0b4fba6863504d6 425 Pfam PF01544 CorA-like Mg2+ transporter protein 128 421 1.6E-68 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 THSYN_RS04135 94888afdad5ecd10c0b4fba6863504d6 425 Gene3D G3DSA:3.30.460.20 65 240 1.7E-42 T 29-03-2018 THSYN_RS11680 e78e1fa4723d81935a54d920d72cb38c 1211 SUPERFAMILY SSF53335 409 517 1.5E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS11680 e78e1fa4723d81935a54d920d72cb38c 1211 SUPERFAMILY SSF53335 565 675 1.5E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS11680 e78e1fa4723d81935a54d920d72cb38c 1211 SUPERFAMILY SSF53335 211 372 1.5E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS11680 e78e1fa4723d81935a54d920d72cb38c 1211 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 353 369 2.2E-8 T 29-03-2018 THSYN_RS11680 e78e1fa4723d81935a54d920d72cb38c 1211 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 573 585 2.2E-8 T 29-03-2018 THSYN_RS11680 e78e1fa4723d81935a54d920d72cb38c 1211 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 413 427 2.2E-8 T 29-03-2018 THSYN_RS11680 e78e1fa4723d81935a54d920d72cb38c 1211 Gene3D G3DSA:3.40.50.150 347 690 1.1E-23 T 29-03-2018 THSYN_RS11680 e78e1fa4723d81935a54d920d72cb38c 1211 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 576 582 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 Gene3D G3DSA:1.25.40.10 621 673 7.4E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 SUPERFAMILY SSF48695 95 220 8.38E-68 T 29-03-2018 IPR011031 Multihaem cytochrome THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 SUPERFAMILY SSF48695 26 50 8.38E-68 T 29-03-2018 IPR011031 Multihaem cytochrome THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 SUPERFAMILY SSF48695 288 554 8.38E-68 T 29-03-2018 IPR011031 Multihaem cytochrome THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 Gene3D G3DSA:1.25.40.10 674 769 6.4E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 Gene3D G3DSA:1.25.40.10 558 620 1.7E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 SUPERFAMILY SSF48452 567 757 1.04E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 Gene3D G3DSA:1.10.1130.10 360 442 4.9E-12 T 29-03-2018 THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 Gene3D G3DSA:1.10.1130.10 15 359 3.7E-54 T 29-03-2018 THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 Gene3D G3DSA:1.25.40.70 454 557 2.1E-4 T 29-03-2018 THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 Pfam PF13435 Cytochrome c554 and c-prime 162 206 7.0E-4 T 29-03-2018 IPR023155 Cytochrome c-552/4 THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 SMART SM00028 621 654 4.4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 SMART SM00028 655 688 0.017 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 SMART SM00028 587 620 0.027 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 Pfam PF14559 Tetratricopeptide repeat 702 764 3.5E-6 T 29-03-2018 THSYN_RS27250 b66845d96cf887f1cfbc317280edf26b 769 Pfam PF14559 Tetratricopeptide repeat 598 661 1.3E-5 T 29-03-2018 THSYN_RS02135 3b4398f7ffb73d822e724f4d73dd6bb3 189 Pfam PF09626 Dihaem cytochrome c 53 174 1.2E-35 T 29-03-2018 IPR018588 Dihaem cytochrome c THSYN_RS02135 3b4398f7ffb73d822e724f4d73dd6bb3 189 Gene3D G3DSA:1.10.1130.10 17 185 8.1E-4 T 29-03-2018 THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 SUPERFAMILY SSF55781 327 506 3.34E-41 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 SMART SM00065 150 324 2.5E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 SMART SM00065 553 694 0.045 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 PRINTS PR01033 Phytochrome signature 252 273 4.8E-18 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 PRINTS PR01033 Phytochrome signature 472 490 4.8E-18 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 PRINTS PR01033 Phytochrome signature 351 371 4.8E-18 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 PRINTS PR01033 Phytochrome signature 165 184 4.8E-18 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 PRINTS PR01033 Phytochrome signature 439 458 4.8E-18 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 Gene3D G3DSA:3.30.450.40 131 318 5.5E-40 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 SUPERFAMILY SSF55781 536 683 2.84E-12 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 SUPERFAMILY SSF55781 143 313 1.53E-56 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 Gene3D G3DSA:3.30.450.40 525 697 1.5E-16 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 Gene3D G3DSA:3.30.450.20 9 124 1.5E-21 T 29-03-2018 THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 Pfam PF00360 Phytochrome region 331 504 4.2E-42 T 29-03-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 SUPERFAMILY SSF55785 10 124 8.22E-31 T 29-03-2018 IPR000014 PAS domain THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 Pfam PF08446 PAS fold 17 124 9.6E-20 T 29-03-2018 IPR013654 PAS fold-2 GO:0006355 THSYN_RS21135 239c4bac21cfe045c6ccdecd95a7dfd9 698 Pfam PF01590 GAF domain 151 298 7.8E-17 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS01535 619ba60ddd317a9e324fd481399adca7 249 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 23 248 4.7E-80 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 THSYN_RS01535 619ba60ddd317a9e324fd481399adca7 249 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 14 248 38.517 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 THSYN_RS01535 619ba60ddd317a9e324fd481399adca7 249 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 34 49 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 THSYN_RS01535 619ba60ddd317a9e324fd481399adca7 249 Gene3D G3DSA:3.40.50.150 3 248 3.8E-44 T 29-03-2018 THSYN_RS01535 619ba60ddd317a9e324fd481399adca7 249 Pfam PF01209 ubiE/COQ5 methyltransferase family 19 248 5.1E-90 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 THSYN_RS01535 619ba60ddd317a9e324fd481399adca7 249 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 156 170 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 THSYN_RS01535 619ba60ddd317a9e324fd481399adca7 249 SUPERFAMILY SSF53335 17 246 6.69E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS14585 26c33521320d4d36a8c208004018322a 531 Gene3D G3DSA:1.10.3720.10 316 525 6.9E-23 T 29-03-2018 THSYN_RS14585 26c33521320d4d36a8c208004018322a 531 SUPERFAMILY SSF161098 3 261 8.37E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS14585 26c33521320d4d36a8c208004018322a 531 Gene3D G3DSA:1.10.3720.10 5 268 1.1E-26 T 29-03-2018 THSYN_RS14585 26c33521320d4d36a8c208004018322a 531 SUPERFAMILY SSF161098 285 523 2.07E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS14585 26c33521320d4d36a8c208004018322a 531 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 360 520 3.7E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS14585 26c33521320d4d36a8c208004018322a 531 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 261 1.1E-9 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS26610 69c3dc737cafae96b7e02d29acb3a205 844 SMART SM00487 7 192 3.5E-15 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS26610 69c3dc737cafae96b7e02d29acb3a205 844 Pfam PF08482 ATP-dependent helicase C-terminal 698 830 3.1E-50 T 29-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal THSYN_RS26610 69c3dc737cafae96b7e02d29acb3a205 844 SMART SM00490 235 333 1.2E-16 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS26610 69c3dc737cafae96b7e02d29acb3a205 844 Pfam PF04408 Helicase associated domain (HA2) 394 453 1.5E-14 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 THSYN_RS26610 69c3dc737cafae96b7e02d29acb3a205 844 Pfam PF00271 Helicase conserved C-terminal domain 213 333 3.4E-12 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS26610 69c3dc737cafae96b7e02d29acb3a205 844 PIRSF PIRSF005496 6 844 1.7E-295 T 29-03-2018 THSYN_RS26610 69c3dc737cafae96b7e02d29acb3a205 844 Gene3D G3DSA:3.40.50.300 186 352 1.3E-41 T 29-03-2018 THSYN_RS26610 69c3dc737cafae96b7e02d29acb3a205 844 SMART SM00847 393 489 4.0E-13 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 THSYN_RS26610 69c3dc737cafae96b7e02d29acb3a205 844 SUPERFAMILY SSF52540 23 343 1.32E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26610 69c3dc737cafae96b7e02d29acb3a205 844 Pfam PF00270 DEAD/DEAH box helicase 21 171 4.9E-6 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS26610 69c3dc737cafae96b7e02d29acb3a205 844 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 10 842 2.3E-285 T 29-03-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 THSYN_RS26610 69c3dc737cafae96b7e02d29acb3a205 844 Gene3D G3DSA:3.40.50.300 16 168 5.6E-23 T 29-03-2018 THSYN_RS19255 191b7483800a1b7a3490f3502023a870 223 SMART SM00419 163 211 4.4E-12 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS19255 191b7483800a1b7a3490f3502023a870 223 Gene3D G3DSA:1.10.10.10 148 221 9.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19255 191b7483800a1b7a3490f3502023a870 223 SUPERFAMILY SSF51206 17 146 3.01E-23 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like THSYN_RS19255 191b7483800a1b7a3490f3502023a870 223 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 169 185 3.4E-5 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS19255 191b7483800a1b7a3490f3502023a870 223 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 185 200 3.4E-5 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS19255 191b7483800a1b7a3490f3502023a870 223 SUPERFAMILY SSF46785 149 219 1.71E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19255 191b7483800a1b7a3490f3502023a870 223 Pfam PF13545 Crp-like helix-turn-helix domain 152 218 1.7E-14 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS19255 191b7483800a1b7a3490f3502023a870 223 Pfam PF00027 Cyclic nucleotide-binding domain 31 118 6.5E-8 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS19255 191b7483800a1b7a3490f3502023a870 223 Gene3D G3DSA:2.60.120.10 14 147 5.0E-13 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS05265 fe5bd134abc788feb3af4e4c70bcb1ae 350 Pfam PF15616 TerY-C metal binding domain 222 350 7.7E-47 T 29-03-2018 IPR028274 TerY-C metal binding domain THSYN_RS05265 fe5bd134abc788feb3af4e4c70bcb1ae 350 Pfam PF00092 von Willebrand factor type A domain 6 158 9.1E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS05265 fe5bd134abc788feb3af4e4c70bcb1ae 350 SUPERFAMILY SSF53300 5 160 3.12E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS05265 fe5bd134abc788feb3af4e4c70bcb1ae 350 Gene3D G3DSA:3.40.50.410 5 161 2.5E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS05265 fe5bd134abc788feb3af4e4c70bcb1ae 350 SMART SM00327 3 180 8.5E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS07920 dd3e90aedccd8a680a690a53746b39dc 378 Pfam PF00005 ABC transporter 38 179 8.5E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS07920 dd3e90aedccd8a680a690a53746b39dc 378 SUPERFAMILY SSF50331 255 376 6.46E-20 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal THSYN_RS07920 dd3e90aedccd8a680a690a53746b39dc 378 SMART SM00382 46 237 2.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS07920 dd3e90aedccd8a680a690a53746b39dc 378 Gene3D G3DSA:2.40.50.100 256 309 1.1E-4 T 29-03-2018 THSYN_RS07920 dd3e90aedccd8a680a690a53746b39dc 378 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS07920 dd3e90aedccd8a680a690a53746b39dc 378 SUPERFAMILY SSF52540 22 260 6.96E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07920 dd3e90aedccd8a680a690a53746b39dc 378 Gene3D G3DSA:3.40.50.300 17 253 9.6E-72 T 29-03-2018 THSYN_RS07920 dd3e90aedccd8a680a690a53746b39dc 378 Pfam PF08402 TOBE domain 296 376 9.2E-15 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THSYN_RS07920 dd3e90aedccd8a680a690a53746b39dc 378 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 52 376 2.4E-125 T 29-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 THSYN_RS30625 06e933bc5a28ad3150a1e2963ef26fff 106 ProDom PD007559 HYDRATASE NITRILE ALPHA SUBUNIT LYASE CHAIN METAL-BINDING DIRECT SEQUENCING NITRILASE 10 60 2.0E-4 T 29-03-2018 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 THSYN_RS30625 06e933bc5a28ad3150a1e2963ef26fff 106 Gene3D G3DSA:3.90.330.10 1 72 2.1E-14 T 29-03-2018 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 THSYN_RS30625 06e933bc5a28ad3150a1e2963ef26fff 106 SUPERFAMILY SSF56209 7 80 5.89E-16 T 29-03-2018 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 THSYN_RS30625 06e933bc5a28ad3150a1e2963ef26fff 106 Pfam PF02979 Nitrile hydratase, alpha chain 8 60 4.7E-8 T 29-03-2018 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 THSYN_RS30625 06e933bc5a28ad3150a1e2963ef26fff 106 TIGRFAM TIGR03793 TOMM_pelo: NHLP leader peptide domain 8 78 6.0E-21 T 29-03-2018 IPR022513 Thiazole/oxazole-modified microcins THSYN_RS07720 c0b5deb56c02dc5d9b7b3012572cadff 747 Gene3D G3DSA:1.20.1000.10 387 737 8.6E-12 T 29-03-2018 THSYN_RS07720 c0b5deb56c02dc5d9b7b3012572cadff 747 Pfam PF00271 Helicase conserved C-terminal domain 216 336 4.4E-16 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS07720 c0b5deb56c02dc5d9b7b3012572cadff 747 Gene3D G3DSA:3.40.50.300 185 375 5.9E-27 T 29-03-2018 THSYN_RS07720 c0b5deb56c02dc5d9b7b3012572cadff 747 SUPERFAMILY SSF52540 269 382 3.8E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07720 c0b5deb56c02dc5d9b7b3012572cadff 747 SUPERFAMILY SSF52540 184 240 3.8E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07720 c0b5deb56c02dc5d9b7b3012572cadff 747 SMART SM00490 256 336 3.0E-20 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS14240 2fb94f97f1c2dd386d5b01679a378721 98 Gene3D G3DSA:3.40.140.10 14 91 4.9E-4 T 29-03-2018 THSYN_RS14240 2fb94f97f1c2dd386d5b01679a378721 98 Pfam PF04002 RadC-like JAB domain 25 71 1.6E-4 T 29-03-2018 IPR025657 RadC-like JAB domain THSYN_RS20850 774597a7066a66a84f78b58d0aaf5bed 357 Gene3D G3DSA:3.60.60.10 30 350 1.6E-89 T 29-03-2018 THSYN_RS20850 774597a7066a66a84f78b58d0aaf5bed 357 SUPERFAMILY SSF56235 33 325 7.64E-88 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS20850 774597a7066a66a84f78b58d0aaf5bed 357 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 33 320 4.2E-45 T 29-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 131 1.5E-24 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 Gene3D G3DSA:3.50.50.60 325 406 1.1E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 Gene3D G3DSA:3.50.50.60 240 324 3.0E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 Gene3D G3DSA:3.50.50.60 411 488 2.8E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 SUPERFAMILY SSF46548 2 154 4.97E-40 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 469 1.7E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 1.8E-24 T 29-03-2018 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 PRINTS PR00419 Adrenodoxin reductase family signature 210 220 1.8E-24 T 29-03-2018 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 1.8E-24 T 29-03-2018 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 PRINTS PR00419 Adrenodoxin reductase family signature 286 300 1.8E-24 T 29-03-2018 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 SUPERFAMILY SSF51971 390 481 1.13E-9 T 29-03-2018 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 487 2.1E-218 T 29-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 Gene3D G3DSA:1.10.1060.10 3 140 4.7E-42 T 29-03-2018 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 Gene3D G3DSA:3.40.50.720 141 239 5.6E-22 T 29-03-2018 THSYN_RS03235 f784e921e616e896fc99aa043128915a 488 SUPERFAMILY SSF51971 142 406 2.41E-65 T 29-03-2018 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 131 1.5E-24 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 Gene3D G3DSA:3.50.50.60 325 406 1.1E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 Gene3D G3DSA:3.50.50.60 240 324 3.0E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 Gene3D G3DSA:3.50.50.60 411 488 2.8E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 SUPERFAMILY SSF46548 2 154 4.97E-40 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 469 1.7E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 1.8E-24 T 29-03-2018 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 PRINTS PR00419 Adrenodoxin reductase family signature 210 220 1.8E-24 T 29-03-2018 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 1.8E-24 T 29-03-2018 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 PRINTS PR00419 Adrenodoxin reductase family signature 286 300 1.8E-24 T 29-03-2018 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 SUPERFAMILY SSF51971 390 481 1.13E-9 T 29-03-2018 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 487 2.1E-218 T 29-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 Gene3D G3DSA:1.10.1060.10 3 140 4.7E-42 T 29-03-2018 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 Gene3D G3DSA:3.40.50.720 141 239 5.6E-22 T 29-03-2018 THSYN_RS03155 f784e921e616e896fc99aa043128915a 488 SUPERFAMILY SSF51971 142 406 2.41E-65 T 29-03-2018 THSYN_RS07875 322fe5b255ef4cc2e496ed9f33d0b9ea 813 SUPERFAMILY SSF53756 2 808 0.0 T 29-03-2018 THSYN_RS07875 322fe5b255ef4cc2e496ed9f33d0b9ea 813 PIRSF PIRSF000460 1 811 1.2E-223 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THSYN_RS07875 322fe5b255ef4cc2e496ed9f33d0b9ea 813 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 3 804 0.0 T 29-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THSYN_RS07875 322fe5b255ef4cc2e496ed9f33d0b9ea 813 Gene3D G3DSA:3.40.50.2000 1 473 5.9E-200 T 29-03-2018 THSYN_RS07875 322fe5b255ef4cc2e496ed9f33d0b9ea 813 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 649 661 - T 29-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THSYN_RS07875 322fe5b255ef4cc2e496ed9f33d0b9ea 813 Gene3D G3DSA:3.40.50.2000 474 789 4.6E-133 T 29-03-2018 THSYN_RS07875 322fe5b255ef4cc2e496ed9f33d0b9ea 813 Pfam PF00343 Carbohydrate phosphorylase 93 804 0.0 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 Pfam PF03705 CheR methyltransferase, all-alpha domain 249 299 1.7E-17 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 SMART SM00138 246 509 2.7E-81 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 SUPERFAMILY SSF52738 43 229 9.55E-58 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 SUPERFAMILY SSF53335 312 508 6.78E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 SUPERFAMILY SSF47757 241 315 9.94E-17 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 Gene3D G3DSA:3.40.50.150 311 511 1.3E-43 T 29-03-2018 THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 Gene3D G3DSA:1.10.155.10 241 309 2.0E-17 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 Gene3D G3DSA:3.40.50.180 38 235 6.2E-66 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 Pfam PF01339 CheB methylesterase 48 223 3.8E-55 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 PRINTS PR00996 Glutamate methyltransferase family signature 268 281 3.3E-30 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 PRINTS PR00996 Glutamate methyltransferase family signature 305 317 3.3E-30 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 PRINTS PR00996 Glutamate methyltransferase family signature 468 491 3.3E-30 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 PRINTS PR00996 Glutamate methyltransferase family signature 449 463 3.3E-30 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 PRINTS PR00996 Glutamate methyltransferase family signature 345 365 3.3E-30 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 PRINTS PR00996 Glutamate methyltransferase family signature 383 399 3.3E-30 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS01990 2ae1e2dfe01f90b42ed7a7015dfa47c3 644 Pfam PF01739 CheR methyltransferase, SAM binding domain 313 504 1.2E-52 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal THSYN_RS28455 d56ef1ec5a300df5db3673b03b1282e8 230 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 135 154 1.6E-50 T 29-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 THSYN_RS28455 d56ef1ec5a300df5db3673b03b1282e8 230 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 213 226 1.6E-50 T 29-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 THSYN_RS28455 d56ef1ec5a300df5db3673b03b1282e8 230 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 182 204 1.6E-50 T 29-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 THSYN_RS28455 d56ef1ec5a300df5db3673b03b1282e8 230 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 18 41 1.6E-50 T 29-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 THSYN_RS28455 d56ef1ec5a300df5db3673b03b1282e8 230 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 56 80 1.6E-50 T 29-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 THSYN_RS28455 d56ef1ec5a300df5db3673b03b1282e8 230 Pfam PF01292 Prokaryotic cytochrome b561 16 221 1.4E-30 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THSYN_RS28455 d56ef1ec5a300df5db3673b03b1282e8 230 TIGRFAM TIGR02125 CytB-hydogenase: Ni/Fe-hydrogenase, b-type cytochrome subunit 14 226 1.1E-69 T 29-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 THSYN_RS28455 d56ef1ec5a300df5db3673b03b1282e8 230 Gene3D G3DSA:1.20.950.20 7 228 1.1E-43 T 29-03-2018 THSYN_RS28455 d56ef1ec5a300df5db3673b03b1282e8 230 SUPERFAMILY SSF81342 11 226 1.8E-41 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 SUPERFAMILY SSF46955 3 51 6.41E-10 T 29-03-2018 IPR009061 Putative DNA-binding domain THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 ProSitePatterns PS01176 Initiation factor 2 signature. 916 938 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 Gene3D G3DSA:3.40.50.10050 781 843 2.1E-21 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 Gene3D G3DSA:2.40.30.10 866 964 2.6E-27 T 29-03-2018 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 SUPERFAMILY SSF52156 743 872 1.11E-34 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 Gene3D G3DSA:3.40.50.300 460 635 3.1E-39 T 29-03-2018 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 963 17.308 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 386 436 3.1E-14 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 46 2.3E-7 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 Pfam PF00009 Elongation factor Tu GTP binding domain 470 626 2.0E-34 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 SUPERFAMILY SSF52540 461 634 3.13E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 SUPERFAMILY SSF50447 867 962 1.85E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 381 963 5.7E-257 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 Pfam PF11987 Translation-initiation factor 2 751 855 2.3E-34 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 Gene3D G3DSA:3.30.56.50 389 430 1.9E-7 T 29-03-2018 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 Gene3D G3DSA:3.30.56.50 4 40 1.5E-10 T 29-03-2018 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 Gene3D G3DSA:2.40.30.10 638 780 1.1E-28 T 29-03-2018 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 65 120 1.9E-16 T 29-03-2018 IPR013575 Initiation factor 2 associated domain, bacterial THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 SUPERFAMILY SSF50447 638 719 4.99E-23 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 469 624 7.3E-32 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS09440 81f9c34110dab3b75bbd4992134923ae 965 Gene3D G3DSA:1.20.1000.10 41 265 0.0014 T 29-03-2018 THSYN_RS07955 6b88b9f737e2c4a587bce6e8ea7b6d26 252 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 243 34.577 T 29-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 THSYN_RS07955 6b88b9f737e2c4a587bce6e8ea7b6d26 252 Gene3D G3DSA:3.20.20.70 1 246 1.2E-55 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS07955 6b88b9f737e2c4a587bce6e8ea7b6d26 252 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 237 1.3E-72 T 29-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 THSYN_RS07955 6b88b9f737e2c4a587bce6e8ea7b6d26 252 Pfam PF00977 Histidine biosynthesis protein 3 235 1.9E-73 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 THSYN_RS07955 6b88b9f737e2c4a587bce6e8ea7b6d26 252 SUPERFAMILY SSF51366 3 238 5.73E-70 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THSYN_RS01770 255b0e3dda49d34ee2bc6f0fc4aeacab 207 SUPERFAMILY SSF53335 26 172 9.53E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS01770 255b0e3dda49d34ee2bc6f0fc4aeacab 207 Gene3D G3DSA:3.40.50.150 3 192 5.8E-13 T 29-03-2018 THSYN_RS01770 255b0e3dda49d34ee2bc6f0fc4aeacab 207 Pfam PF13649 Methyltransferase domain 53 136 2.3E-6 T 29-03-2018 THSYN_RS30870 f9f01fc2ecf19028b8d59213667e868e 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 18 188 3.0E-25 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS30870 f9f01fc2ecf19028b8d59213667e868e 225 SUPERFAMILY SSF56784 14 219 8.4E-39 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS30870 f9f01fc2ecf19028b8d59213667e868e 225 Gene3D G3DSA:3.40.50.1000 6 214 1.7E-25 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 SUPERFAMILY SSF53067 159 393 2.16E-80 T 29-03-2018 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 TIGRFAM TIGR00016 ackA: acetate kinase 3 389 3.0E-112 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 SUPERFAMILY SSF53067 4 195 1.64E-55 T 29-03-2018 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 204 221 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 Gene3D G3DSA:3.30.420.40 4 195 2.4E-57 T 29-03-2018 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 Pfam PF00871 Acetokinase family 5 386 5.3E-107 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 Hamap MF_00020 Acetate kinase [ackA]. 1 396 159.504 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 PRINTS PR00471 Acetate kinase family signature 5 16 1.6E-40 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 PRINTS PR00471 Acetate kinase family signature 320 336 1.6E-40 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 PRINTS PR00471 Acetate kinase family signature 204 225 1.6E-40 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 PRINTS PR00471 Acetate kinase family signature 374 386 1.6E-40 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 PRINTS PR00471 Acetate kinase family signature 298 311 1.6E-40 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 PRINTS PR00471 Acetate kinase family signature 175 188 1.6E-40 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 PIRSF PIRSF000722 1 396 1.7E-138 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS06275 b60821ead436f3492b88fcb5f6532f9a 397 Gene3D G3DSA:3.30.420.40 198 396 2.1E-73 T 29-03-2018 THSYN_RS17490 bb7dbdb8a4bc3275df2f66bcfb9fd21f 347 Pfam PF00445 Ribonuclease T2 family 137 301 2.9E-16 T 29-03-2018 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 Reactome: R-HSA-6798695 THSYN_RS17490 bb7dbdb8a4bc3275df2f66bcfb9fd21f 347 ProSitePatterns PS00530 Ribonuclease T2 family histidine active site 1. 169 176 - T 29-03-2018 IPR018188 Ribonuclease T2, His active site 1 GO:0003723|GO:0033897 Reactome: R-HSA-6798695 THSYN_RS17490 bb7dbdb8a4bc3275df2f66bcfb9fd21f 347 Gene3D G3DSA:3.90.730.10 112 340 2.1E-31 T 29-03-2018 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 Reactome: R-HSA-6798695 THSYN_RS17490 bb7dbdb8a4bc3275df2f66bcfb9fd21f 347 SUPERFAMILY SSF55895 135 316 3.79E-26 T 29-03-2018 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 Reactome: R-HSA-6798695 THSYN_RS17490 bb7dbdb8a4bc3275df2f66bcfb9fd21f 347 ProSitePatterns PS00531 Ribonuclease T2 family histidine active site 2. 226 237 - T 29-03-2018 IPR033130 Ribonuclease T2, His active site 2 Reactome: R-HSA-6798695 THSYN_RS08370 51f10b793c8a774c02ce2f3cea9e9393 190 SUPERFAMILY SSF89069 13 74 2.75E-11 T 29-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 THSYN_RS08370 51f10b793c8a774c02ce2f3cea9e9393 190 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 13 82 1.6E-11 T 29-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 SMART SM00278 131 150 4.5 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 SMART SM00278 195 214 140.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 Gene3D G3DSA:3.40.50.300 503 715 8.6E-33 T 29-03-2018 THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 SMART SM00382 347 530 6.7E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 Pfam PF14490 Helix-hairpin-helix containing domain 154 242 1.3E-30 T 29-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 Pfam PF14520 Helix-hairpin-helix domain 102 146 9.5E-8 T 29-03-2018 THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 Gene3D G3DSA:1.10.150.20 163 203 0.014 T 29-03-2018 THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 Gene3D G3DSA:3.40.50.300 281 502 2.2E-37 T 29-03-2018 THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 SUPERFAMILY SSF47781 93 170 2.2E-9 T 29-03-2018 IPR010994 RuvA domain 2-like THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 Pfam PF13538 UvrD-like helicase C-terminal domain 655 702 5.7E-18 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 Gene3D G3DSA:1.10.150.20 204 227 0.16 T 29-03-2018 THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 Pfam PF13604 AAA domain 334 513 2.2E-45 T 29-03-2018 THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 Gene3D G3DSA:1.10.150.20 93 162 3.5E-8 T 29-03-2018 THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 17 728 6.0E-206 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 14 732 27.673 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 SUPERFAMILY SSF52540 193 492 8.47E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 SUPERFAMILY SSF52540 444 510 7.59E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27020 bd2ccdfa93a4bef64d12acf35325ba63 743 SUPERFAMILY SSF52540 555 727 7.59E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15785 a24f058459453aa8d8b311f063f9c983 441 Pfam PF01926 50S ribosome-binding GTPase 200 304 7.0E-17 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS15785 a24f058459453aa8d8b311f063f9c983 441 Hamap MF_00900 GTPase HflX [hflX]. 26 390 45.147 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 THSYN_RS15785 a24f058459453aa8d8b311f063f9c983 441 Pfam PF16360 GTP-binding GTPase Middle Region 114 192 4.5E-27 T 29-03-2018 IPR032305 GTP-binding protein, middle domain THSYN_RS15785 a24f058459453aa8d8b311f063f9c983 441 Pfam PF13167 GTP-binding GTPase N-terminal 27 112 3.5E-26 T 29-03-2018 IPR025121 GTPase HflX, N-terminal THSYN_RS15785 a24f058459453aa8d8b311f063f9c983 441 SUPERFAMILY SSF52540 198 362 2.07E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15785 a24f058459453aa8d8b311f063f9c983 441 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 1.4E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS15785 a24f058459453aa8d8b311f063f9c983 441 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 267 285 1.4E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS15785 a24f058459453aa8d8b311f063f9c983 441 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 360 9.6E-144 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 THSYN_RS15785 a24f058459453aa8d8b311f063f9c983 441 Gene3D G3DSA:3.40.50.300 231 376 2.5E-16 T 29-03-2018 THSYN_RS15785 a24f058459453aa8d8b311f063f9c983 441 Gene3D G3DSA:3.40.50.300 171 230 5.1E-11 T 29-03-2018 THSYN_RS15785 a24f058459453aa8d8b311f063f9c983 441 PIRSF PIRSF006809 3 415 8.0E-134 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 THSYN_RS33155 1336be0ce2bf3ea876470b6bbb890bc3 528 Pfam PF03050 Transposase IS66 family 219 484 3.8E-43 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS21450 1336be0ce2bf3ea876470b6bbb890bc3 528 Pfam PF03050 Transposase IS66 family 219 484 3.8E-43 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS06145 1336be0ce2bf3ea876470b6bbb890bc3 528 Pfam PF03050 Transposase IS66 family 219 484 3.8E-43 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS08105 1336be0ce2bf3ea876470b6bbb890bc3 528 Pfam PF03050 Transposase IS66 family 219 484 3.8E-43 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS28460 1336be0ce2bf3ea876470b6bbb890bc3 528 Pfam PF03050 Transposase IS66 family 219 484 3.8E-43 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS32615 1336be0ce2bf3ea876470b6bbb890bc3 528 Pfam PF03050 Transposase IS66 family 219 484 3.8E-43 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS18230 1336be0ce2bf3ea876470b6bbb890bc3 528 Pfam PF03050 Transposase IS66 family 219 484 3.8E-43 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS16050 c8fea98bc025f24660a8fda81b16c53f 244 SMART SM00331 13 239 1.2E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS16050 c8fea98bc025f24660a8fda81b16c53f 244 SUPERFAMILY SSF81606 6 240 7.72E-61 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS16050 c8fea98bc025f24660a8fda81b16c53f 244 Pfam PF13672 Protein phosphatase 2C 17 202 2.6E-15 T 29-03-2018 THSYN_RS16050 c8fea98bc025f24660a8fda81b16c53f 244 SMART SM00332 1 237 6.0E-24 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS16050 c8fea98bc025f24660a8fda81b16c53f 244 Gene3D G3DSA:3.60.40.10 6 240 1.3E-41 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS03505 f63ae5560c93b43e8d2857277cbb3700 366 SUPERFAMILY SSF63829 21 189 1.63E-24 T 29-03-2018 THSYN_RS03505 f63ae5560c93b43e8d2857277cbb3700 366 SUPERFAMILY SSF63829 219 342 1.63E-24 T 29-03-2018 THSYN_RS03505 f63ae5560c93b43e8d2857277cbb3700 366 Pfam PF03022 Major royal jelly protein 96 339 6.4E-26 T 29-03-2018 IPR017996 Major royal jelly protein/protein yellow THSYN_RS03505 f63ae5560c93b43e8d2857277cbb3700 366 Gene3D G3DSA:2.120.10.30 26 365 3.9E-39 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS16135 d8dce2ee706b415510d4a3806f635306 193 SUPERFAMILY SSF81324 99 180 2.35E-11 T 29-03-2018 THSYN_RS16135 d8dce2ee706b415510d4a3806f635306 193 Gene3D G3DSA:1.10.287.70 95 182 8.4E-11 T 29-03-2018 THSYN_RS16135 d8dce2ee706b415510d4a3806f635306 193 Pfam PF07885 Ion channel 131 179 1.1E-9 T 29-03-2018 IPR013099 Potassium channel domain THSYN_RS24040 59bfe413b692ffedc3fe035623e1bb9b 404 Gene3D G3DSA:3.90.550.10 4 280 1.1E-37 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS24040 59bfe413b692ffedc3fe035623e1bb9b 404 SUPERFAMILY SSF53448 342 358 1.15E-45 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS24040 59bfe413b692ffedc3fe035623e1bb9b 404 SUPERFAMILY SSF53448 5 274 1.15E-45 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS24040 59bfe413b692ffedc3fe035623e1bb9b 404 SUPERFAMILY SSF51161 312 402 4.52E-15 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS24040 59bfe413b692ffedc3fe035623e1bb9b 404 Pfam PF00483 Nucleotidyl transferase 8 270 3.1E-31 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THSYN_RS24040 59bfe413b692ffedc3fe035623e1bb9b 404 Gene3D G3DSA:2.160.10.10 286 395 8.0E-8 T 29-03-2018 THSYN_RS17435 7de44b3ccb8bb39826210f35f3247c41 107 SMART SM00450 6 101 3.7E-18 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS17435 7de44b3ccb8bb39826210f35f3247c41 107 SUPERFAMILY SSF52821 3 101 1.7E-29 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS17435 7de44b3ccb8bb39826210f35f3247c41 107 Gene3D G3DSA:3.40.250.10 1 104 7.6E-24 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS17435 7de44b3ccb8bb39826210f35f3247c41 107 Pfam PF00581 Rhodanese-like domain 13 97 5.0E-9 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS02890 d3a79288422cf57b2ce1720873d81a96 93 SUPERFAMILY SSF47413 23 90 1.63E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS02890 d3a79288422cf57b2ce1720873d81a96 93 Gene3D G3DSA:1.10.10.60 19 52 8.5E-4 T 29-03-2018 THSYN_RS02890 d3a79288422cf57b2ce1720873d81a96 93 Pfam PF13744 Helix-turn-helix domain 19 91 1.6E-13 T 29-03-2018 THSYN_RS02890 d3a79288422cf57b2ce1720873d81a96 93 Gene3D G3DSA:3.30.1190.10 53 93 5.5E-6 T 29-03-2018 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SMART SM00028 788 821 43.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SMART SM00028 140 173 9.9 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SMART SM00028 174 207 340.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SMART SM00028 310 343 120.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SMART SM00028 208 241 51.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SMART SM00028 514 547 150.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SMART SM00028 618 651 210.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SMART SM00028 479 512 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Gene3D G3DSA:1.25.40.10 290 494 7.7E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SUPERFAMILY SSF48452 146 366 1.28E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Gene3D G3DSA:1.25.40.10 253 289 0.039 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Gene3D G3DSA:1.25.40.10 495 566 5.2E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SUPERFAMILY SSF48452 568 689 2.85E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SUPERFAMILY SSF48452 737 770 2.85E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Gene3D G3DSA:1.25.40.10 804 846 0.0057 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Gene3D G3DSA:1.25.40.10 847 939 2.8E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 TIGRFAM TIGR02917 PEP_TPR_lipo: putative PEP-CTERM system TPR-repeat lipoprotein 36 920 7.1E-107 T 29-03-2018 IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SUPERFAMILY SSF48452 386 549 1.71E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Gene3D G3DSA:1.25.40.10 716 803 5.7E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SUPERFAMILY SSF48452 36 123 3.8E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Gene3D G3DSA:1.25.40.10 26 117 7.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Pfam PF13432 Tetratricopeptide repeat 181 238 0.012 T 29-03-2018 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 SUPERFAMILY SSF48452 781 913 1.06E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Pfam PF14559 Tetratricopeptide repeat 286 353 1.3E-5 T 29-03-2018 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Pfam PF14559 Tetratricopeptide repeat 491 555 2.2E-6 T 29-03-2018 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Pfam PF14559 Tetratricopeptide repeat 869 937 2.6E-6 T 29-03-2018 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Pfam PF14559 Tetratricopeptide repeat 567 624 1.9E-5 T 29-03-2018 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Gene3D G3DSA:1.25.40.10 224 252 0.0025 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Gene3D G3DSA:1.25.40.10 567 715 6.8E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16935 cfb8c576fba99666fab035530fbab0c8 939 Gene3D G3DSA:1.25.40.10 118 223 4.4E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27850 181e82bc27cdfee34a80bb18ab1f95b1 273 Pfam PF05685 Putative restriction endonuclease 40 206 3.5E-13 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS27850 181e82bc27cdfee34a80bb18ab1f95b1 273 SUPERFAMILY SSF52980 24 210 1.55E-16 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS27850 181e82bc27cdfee34a80bb18ab1f95b1 273 Gene3D G3DSA:3.90.1570.10 21 210 3.8E-19 T 29-03-2018 THSYN_RS14645 d8563004df5e8c74222b67b5a2144a3b 483 Gene3D G3DSA:3.30.230.10 282 470 2.3E-35 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS14645 d8563004df5e8c74222b67b5a2144a3b 483 SUPERFAMILY SSF54211 292 468 4.93E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS14645 d8563004df5e8c74222b67b5a2144a3b 483 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 269 467 8.7E-38 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 THSYN_RS14645 d8563004df5e8c74222b67b5a2144a3b 483 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 371 390 4.2E-20 T 29-03-2018 THSYN_RS14645 d8563004df5e8c74222b67b5a2144a3b 483 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 401 420 4.2E-20 T 29-03-2018 THSYN_RS14645 d8563004df5e8c74222b67b5a2144a3b 483 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 54 73 4.2E-20 T 29-03-2018 THSYN_RS14645 d8563004df5e8c74222b67b5a2144a3b 483 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 424 442 4.2E-20 T 29-03-2018 THSYN_RS14645 d8563004df5e8c74222b67b5a2144a3b 483 Gene3D G3DSA:1.10.8.60 189 281 3.6E-10 T 29-03-2018 THSYN_RS14645 d8563004df5e8c74222b67b5a2144a3b 483 Gene3D G3DSA:3.40.50.300 14 188 3.8E-12 T 29-03-2018 THSYN_RS14645 d8563004df5e8c74222b67b5a2144a3b 483 SUPERFAMILY SSF52540 17 250 3.24E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14645 d8563004df5e8c74222b67b5a2144a3b 483 Pfam PF08298 PrkA AAA domain 12 73 1.5E-4 T 29-03-2018 IPR013153 PrkA AAA domain THSYN_RS11870 5abf9045025f17cdb25202cd9a8e884a 176 Gene3D G3DSA:2.60.40.790 85 176 2.2E-14 T 29-03-2018 IPR008978 HSP20-like chaperone THSYN_RS11870 5abf9045025f17cdb25202cd9a8e884a 176 Pfam PF05455 GvpH 8 135 4.0E-5 T 29-03-2018 IPR008633 Protein GvpH THSYN_RS11870 5abf9045025f17cdb25202cd9a8e884a 176 SUPERFAMILY SSF49764 91 173 1.26E-14 T 29-03-2018 IPR008978 HSP20-like chaperone THSYN_RS16205 2990903eee43a724cd9e48991e6a70e7 318 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 318 71.509 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THSYN_RS16205 2990903eee43a724cd9e48991e6a70e7 318 Gene3D G3DSA:3.40.47.10 3 162 3.0E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS16205 2990903eee43a724cd9e48991e6a70e7 318 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 184 9.8E-34 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THSYN_RS16205 2990903eee43a724cd9e48991e6a70e7 318 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 229 318 2.0E-36 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THSYN_RS16205 2990903eee43a724cd9e48991e6a70e7 318 SUPERFAMILY SSF53901 4 318 1.8E-72 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS16205 2990903eee43a724cd9e48991e6a70e7 318 Gene3D G3DSA:3.40.47.10 163 318 2.3E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS16205 2990903eee43a724cd9e48991e6a70e7 318 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 3 318 5.8E-129 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THSYN_RS21270 469d15ce9d9002430c8ab49791d9a94b 179 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 8 143 2.3E-47 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 THSYN_RS21270 469d15ce9d9002430c8ab49791d9a94b 179 Gene3D G3DSA:3.40.50.300 6 174 1.4E-26 T 29-03-2018 THSYN_RS21270 469d15ce9d9002430c8ab49791d9a94b 179 SUPERFAMILY SSF52540 6 148 3.75E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21270 469d15ce9d9002430c8ab49791d9a94b 179 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 8 167 5.0E-39 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 THSYN_RS10865 d9bebf29c4efbeffe382217621133f20 329 Gene3D G3DSA:3.30.200.20 6 108 2.8E-15 T 29-03-2018 THSYN_RS10865 d9bebf29c4efbeffe382217621133f20 329 Pfam PF01636 Phosphotransferase enzyme family 36 266 1.8E-39 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase THSYN_RS10865 d9bebf29c4efbeffe382217621133f20 329 SUPERFAMILY SSF56112 6 328 7.29E-85 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS10865 d9bebf29c4efbeffe382217621133f20 329 Gene3D G3DSA:3.90.1200.10 112 326 6.0E-24 T 29-03-2018 THSYN_RS10865 d9bebf29c4efbeffe382217621133f20 329 Hamap MF_01497 Stress response kinase A [srkA]. 5 322 47.748 T 29-03-2018 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 THSYN_RS10610 054901c10b7ad2f11eb9d2408a7dfa30 298 SMART SM01091 202 280 1.8E-27 T 29-03-2018 IPR005170 Transporter-associated domain THSYN_RS10610 054901c10b7ad2f11eb9d2408a7dfa30 298 Pfam PF03471 Transporter associated domain 204 279 3.0E-20 T 29-03-2018 IPR005170 Transporter-associated domain THSYN_RS10610 054901c10b7ad2f11eb9d2408a7dfa30 298 SUPERFAMILY SSF54631 61 199 2.15E-33 T 29-03-2018 THSYN_RS10610 054901c10b7ad2f11eb9d2408a7dfa30 298 Pfam PF00571 CBS domain 65 122 8.7E-9 T 29-03-2018 IPR000644 CBS domain THSYN_RS10610 054901c10b7ad2f11eb9d2408a7dfa30 298 Pfam PF00571 CBS domain 137 186 1.9E-4 T 29-03-2018 IPR000644 CBS domain THSYN_RS10610 054901c10b7ad2f11eb9d2408a7dfa30 298 SUPERFAMILY SSF56176 200 287 7.63E-22 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THSYN_RS10610 054901c10b7ad2f11eb9d2408a7dfa30 298 SMART SM00116 74 123 1.1E-4 T 29-03-2018 IPR000644 CBS domain THSYN_RS10610 054901c10b7ad2f11eb9d2408a7dfa30 298 SMART SM00116 138 186 0.26 T 29-03-2018 IPR000644 CBS domain THSYN_RS10610 054901c10b7ad2f11eb9d2408a7dfa30 298 Gene3D G3DSA:3.30.465.10 193 280 2.9E-25 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THSYN_RS10610 054901c10b7ad2f11eb9d2408a7dfa30 298 Gene3D G3DSA:3.10.580.10 44 192 3.4E-36 T 29-03-2018 THSYN_RS16930 d3029c96ea9f58361ca245765b905506 348 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 324 347 0.0011 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS16930 d3029c96ea9f58361ca245765b905506 348 Gene3D G3DSA:3.40.50.880 72 259 0.0013 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS10640 39d7deac065b165f8020369ac1fd7770 525 Pfam PF14516 AAA-like domain 40 353 4.8E-10 T 29-03-2018 THSYN_RS10640 39d7deac065b165f8020369ac1fd7770 525 Gene3D G3DSA:3.40.50.300 21 314 3.7E-9 T 29-03-2018 THSYN_RS10640 39d7deac065b165f8020369ac1fd7770 525 SUPERFAMILY SSF52540 26 281 1.78E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30175 fc56bdef2289d6a5600c9a74b8a3ddbe 916 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 143 155 5.7E-6 T 29-03-2018 THSYN_RS30175 fc56bdef2289d6a5600c9a74b8a3ddbe 916 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 83 97 5.7E-6 T 29-03-2018 THSYN_RS30175 fc56bdef2289d6a5600c9a74b8a3ddbe 916 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 48 64 5.7E-6 T 29-03-2018 THSYN_RS30175 fc56bdef2289d6a5600c9a74b8a3ddbe 916 Pfam PF00176 SNF2 family N-terminal domain 613 819 5.7E-8 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THSYN_RS30175 fc56bdef2289d6a5600c9a74b8a3ddbe 916 SUPERFAMILY SSF52540 527 697 2.44E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30175 fc56bdef2289d6a5600c9a74b8a3ddbe 916 Gene3D G3DSA:3.40.50.150 31 232 3.7E-7 T 29-03-2018 THSYN_RS30175 fc56bdef2289d6a5600c9a74b8a3ddbe 916 Gene3D G3DSA:3.40.50.10810 519 774 3.9E-14 T 29-03-2018 THSYN_RS30175 fc56bdef2289d6a5600c9a74b8a3ddbe 916 SUPERFAMILY SSF53335 46 247 3.25E-10 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS27180 9b52629a8a58cfeddf0d4f11e7ec4943 717 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 215 297 5.0E-7 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THSYN_RS27180 9b52629a8a58cfeddf0d4f11e7ec4943 717 Gene3D G3DSA:3.30.1490.20 202 285 6.3E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS27180 9b52629a8a58cfeddf0d4f11e7ec4943 717 SUPERFAMILY SSF56059 216 326 1.94E-33 T 29-03-2018 THSYN_RS27180 9b52629a8a58cfeddf0d4f11e7ec4943 717 SUPERFAMILY SSF56059 386 472 1.94E-33 T 29-03-2018 THSYN_RS27180 9b52629a8a58cfeddf0d4f11e7ec4943 717 Gene3D G3DSA:3.30.470.20 286 460 7.6E-24 T 29-03-2018 THSYN_RS27180 9b52629a8a58cfeddf0d4f11e7ec4943 717 SUPERFAMILY SSF53623 444 715 5.5E-21 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS27180 9b52629a8a58cfeddf0d4f11e7ec4943 717 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 4 715 1.1E-272 T 29-03-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 THSYN_RS27180 9b52629a8a58cfeddf0d4f11e7ec4943 717 Pfam PF08245 Mur ligase middle domain 486 643 2.0E-5 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS27180 9b52629a8a58cfeddf0d4f11e7ec4943 717 Gene3D G3DSA:3.40.1190.10 472 717 1.1E-28 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS32710 1f206e5e4b4f87ffb60378cf82f6fa1d 169 Pfam PF01471 Putative peptidoglycan binding domain 106 147 2.3E-8 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS32710 1f206e5e4b4f87ffb60378cf82f6fa1d 169 Gene3D G3DSA:1.10.101.10 100 168 1.4E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS32710 1f206e5e4b4f87ffb60378cf82f6fa1d 169 SUPERFAMILY SSF47090 106 147 8.24E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS30015 5daca546ad8c8e8bd4ebb2c6a2c458fe 525 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 54 76 5.3E-5 T 29-03-2018 THSYN_RS30015 5daca546ad8c8e8bd4ebb2c6a2c458fe 525 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 406 422 5.3E-5 T 29-03-2018 THSYN_RS30015 5daca546ad8c8e8bd4ebb2c6a2c458fe 525 Gene3D G3DSA:3.90.660.10 306 468 5.6E-26 T 29-03-2018 THSYN_RS30015 5daca546ad8c8e8bd4ebb2c6a2c458fe 525 Gene3D G3DSA:3.50.50.60 38 305 2.3E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS30015 5daca546ad8c8e8bd4ebb2c6a2c458fe 525 SUPERFAMILY SSF51905 480 512 2.37E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS30015 5daca546ad8c8e8bd4ebb2c6a2c458fe 525 SUPERFAMILY SSF51905 52 380 2.37E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS30015 5daca546ad8c8e8bd4ebb2c6a2c458fe 525 Pfam PF01593 Flavin containing amine oxidoreductase 268 510 1.9E-34 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THSYN_RS30015 5daca546ad8c8e8bd4ebb2c6a2c458fe 525 Pfam PF01593 Flavin containing amine oxidoreductase 62 146 8.7E-14 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THSYN_RS30015 5daca546ad8c8e8bd4ebb2c6a2c458fe 525 SUPERFAMILY SSF54373 360 468 1.83E-20 T 29-03-2018 THSYN_RS03465 08da63a0bbd219ba79a879e7f74e9eb7 404 Gene3D G3DSA:3.60.70.12 5 275 7.1E-99 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THSYN_RS03465 08da63a0bbd219ba79a879e7f74e9eb7 404 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 13 404 7.8E-119 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THSYN_RS03465 08da63a0bbd219ba79a879e7f74e9eb7 404 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 21 404 1.0E-116 T 29-03-2018 THSYN_RS03465 08da63a0bbd219ba79a879e7f74e9eb7 404 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 404 149.593 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THSYN_RS03465 08da63a0bbd219ba79a879e7f74e9eb7 404 SUPERFAMILY SSF56266 12 401 6.67E-134 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THSYN_RS03465 08da63a0bbd219ba79a879e7f74e9eb7 404 Pfam PF01960 ArgJ family 18 404 2.3E-140 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THSYN_RS16045 7b73eb677519d80a2426f785832f6d02 247 PIRSF PIRSF029287 1 231 2.2E-64 T 29-03-2018 IPR017748 Type VI secretion system-associated, BMAA0400 THSYN_RS16045 7b73eb677519d80a2426f785832f6d02 247 Pfam PF09867 Uncharacterized protein conserved in bacteria (DUF2094) 7 139 1.4E-48 T 29-03-2018 IPR017748 Type VI secretion system-associated, BMAA0400 THSYN_RS16045 7b73eb677519d80a2426f785832f6d02 247 TIGRFAM TIGR03373 VI_minor_4: type VI secretion-associated protein, BMA_A0400 family 7 137 1.6E-46 T 29-03-2018 IPR017748 Type VI secretion system-associated, BMAA0400 THSYN_RS16045 7b73eb677519d80a2426f785832f6d02 247 Gene3D G3DSA:3.40.1730.10 5 235 3.6E-73 T 29-03-2018 THSYN_RS11720 26a198d2b5c4fa9620d4c9194711a566 56 Gene3D G3DSA:3.30.70.270 1 48 7.1E-8 T 29-03-2018 THSYN_RS11720 26a198d2b5c4fa9620d4c9194711a566 56 SUPERFAMILY SSF55073 1 31 1.18E-6 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS11720 26a198d2b5c4fa9620d4c9194711a566 56 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1 31 1.8E-7 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS12300 6bf5773214b1494849d9f8790ad99c71 391 Gene3D G3DSA:3.90.1150.10 276 391 2.3E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS12300 6bf5773214b1494849d9f8790ad99c71 391 SUPERFAMILY SSF53383 7 388 7.84E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS12300 6bf5773214b1494849d9f8790ad99c71 391 Pfam PF00155 Aminotransferase class I and II 46 381 1.7E-35 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THSYN_RS12300 6bf5773214b1494849d9f8790ad99c71 391 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 8 388 2.4E-155 T 29-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 THSYN_RS12300 6bf5773214b1494849d9f8790ad99c71 391 Gene3D G3DSA:3.40.640.10 47 275 3.2E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS32475 f72ea65baa2b740efe80b37d200b6d4d 298 SUPERFAMILY SSF54975 1 136 2.81E-36 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THSYN_RS32475 f72ea65baa2b740efe80b37d200b6d4d 298 Pfam PF04940 Sensors of blue-light using FAD 1 92 3.9E-29 T 29-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 THSYN_RS32475 f72ea65baa2b740efe80b37d200b6d4d 298 SMART SM01034 1 93 1.4E-43 T 29-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 THSYN_RS32475 f72ea65baa2b740efe80b37d200b6d4d 298 Pfam PF06146 Phosphate-starvation-inducible E 210 277 9.2E-19 T 29-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 Gene3D G3DSA:3.40.50.300 26 269 1.0E-45 T 29-03-2018 THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 SUPERFAMILY SSF52540 4 268 1.0E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 Gene3D G3DSA:3.30.250.10 270 327 2.4E-27 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 Pfam PF00154 recA bacterial DNA recombination protein 7 269 2.3E-146 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 325 1.3E-174 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 Hamap MF_00268 Protein RecA [recA]. 5 330 52.613 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 SUPERFAMILY SSF54752 269 326 3.79E-21 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 ProSitePatterns PS00321 recA signature. 214 222 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 SMART SM00382 58 229 2.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 PRINTS PR00142 RecA protein signature 128 157 1.9E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 PRINTS PR00142 RecA protein signature 94 123 1.9E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 PRINTS PR00142 RecA protein signature 166 195 1.9E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 PRINTS PR00142 RecA protein signature 244 273 1.9E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 PRINTS PR00142 RecA protein signature 211 239 1.9E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THSYN_RS28030 49fa62c15860311deffbac0c3173a75e 352 PRINTS PR00142 RecA protein signature 298 315 1.9E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THSYN_RS09480 d0d9c94f7f0193895969a2268ca1664b 360 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 238 255 - T 29-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 THSYN_RS09480 d0d9c94f7f0193895969a2268ca1664b 360 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 7 296 3.5E-73 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 THSYN_RS09480 d0d9c94f7f0193895969a2268ca1664b 360 SUPERFAMILY SSF51445 5 306 5.79E-81 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS09480 d0d9c94f7f0193895969a2268ca1664b 360 Gene3D G3DSA:3.20.20.300 3 340 7.8E-77 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 THSYN_RS09480 d0d9c94f7f0193895969a2268ca1664b 360 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 5 340 49.262 T 29-03-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 THSYN_RS28075 668b30beb04492851182763dfee64905 102 Pfam PF04341 Protein of unknown function, DUF485 11 99 2.2E-34 T 29-03-2018 IPR007436 Protein of unknown function DUF485 THSYN_RS32805 122a66d3bc5017df82e7ee52463767c6 202 Pfam PF12635 Protein of unknown function (DUF3780) 17 189 6.3E-70 T 29-03-2018 IPR024220 Protein of unknown function DUF3780 THSYN_RS00740 43dba2d3d0e6aacb1c3678cbcd54a0e9 97 Gene3D G3DSA:1.10.1330.10 52 97 1.2E-6 T 29-03-2018 THSYN_RS00740 43dba2d3d0e6aacb1c3678cbcd54a0e9 97 SUPERFAMILY SSF47473 35 92 1.2E-8 T 29-03-2018 IPR011992 EF-hand domain pair THSYN_RS00740 43dba2d3d0e6aacb1c3678cbcd54a0e9 97 Pfam PF13202 EF hand 73 85 0.091 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS00740 43dba2d3d0e6aacb1c3678cbcd54a0e9 97 Pfam PF13202 EF hand 41 54 0.004 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 THSYN_RS00740 43dba2d3d0e6aacb1c3678cbcd54a0e9 97 Gene3D G3DSA:1.10.238.10 10 51 6.6E-4 T 29-03-2018 THSYN_RS00740 43dba2d3d0e6aacb1c3678cbcd54a0e9 97 ProSitePatterns PS00018 EF-hand calcium-binding domain. 73 85 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS27600 6b260fd840f2c968d8886add64a845b0 289 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 14 289 43.651 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 THSYN_RS27600 6b260fd840f2c968d8886add64a845b0 289 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 194 200 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS27600 6b260fd840f2c968d8886add64a845b0 289 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 31 287 8.4E-68 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 THSYN_RS27600 6b260fd840f2c968d8886add64a845b0 289 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 36 285 9.2E-85 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 THSYN_RS27600 6b260fd840f2c968d8886add64a845b0 289 Pfam PF05175 Methyltransferase small domain 118 205 2.5E-14 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 THSYN_RS27600 6b260fd840f2c968d8886add64a845b0 289 Gene3D G3DSA:3.40.50.150 93 288 2.1E-43 T 29-03-2018 THSYN_RS27600 6b260fd840f2c968d8886add64a845b0 289 SUPERFAMILY SSF53335 23 287 1.14E-56 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS27600 6b260fd840f2c968d8886add64a845b0 289 Gene3D G3DSA:1.10.8.10 13 92 8.5E-19 T 29-03-2018 THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 SUPERFAMILY SSF141868 452 699 1.27E-88 T 29-03-2018 IPR001633 EAL domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 SMART SM00267 259 436 4.8E-56 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 SUPERFAMILY SSF55073 275 438 1.02E-45 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 Gene3D G3DSA:3.30.450.20 16 146 5.4E-19 T 29-03-2018 THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 Gene3D G3DSA:3.20.20.450 438 706 7.7E-99 T 29-03-2018 IPR001633 EAL domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 SUPERFAMILY SSF55785 154 255 9.07E-28 T 29-03-2018 IPR000014 PAS domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 151 265 6.6E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 145 2.2E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 SMART SM00086 217 259 3.1E-6 T 29-03-2018 IPR001610 PAC motif THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 SMART SM00086 97 138 11.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 Pfam PF00563 EAL domain 454 687 1.9E-67 T 29-03-2018 IPR001633 EAL domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 Gene3D G3DSA:3.30.70.270 262 437 2.5E-56 T 29-03-2018 THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 268 435 7.5E-38 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 SMART SM00091 22 90 4.4E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 SMART SM00091 143 211 0.0026 T 29-03-2018 IPR000014 PAS domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 Gene3D G3DSA:3.40.50.10600 147 261 6.2E-27 T 29-03-2018 THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 Pfam PF00990 Diguanylate cyclase, GGDEF domain 270 432 2.6E-44 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 Pfam PF13426 PAS domain 157 258 9.8E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 Pfam PF13426 PAS domain 33 112 3.0E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 SMART SM00052 446 692 8.2E-113 T 29-03-2018 IPR001633 EAL domain THSYN_RS06545 a75b88334b776e54edf168c1c8c0506b 737 SUPERFAMILY SSF55785 41 146 4.75E-19 T 29-03-2018 IPR000014 PAS domain THSYN_RS20485 f5c2a016fe477cd28c4d582b1a3f41ed 268 Gene3D G3DSA:3.40.50.150 64 220 1.4E-11 T 29-03-2018 THSYN_RS20485 f5c2a016fe477cd28c4d582b1a3f41ed 268 SUPERFAMILY SSF53335 83 220 1.34E-13 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS20485 f5c2a016fe477cd28c4d582b1a3f41ed 268 Pfam PF08241 Methyltransferase domain 83 131 4.6E-6 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THSYN_RS12545 e4eefc72efd58d6e1efd88a5714ded50 328 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 71 250 3.1E-14 T 29-03-2018 IPR000477 Reverse transcriptase domain THSYN_RS12545 e4eefc72efd58d6e1efd88a5714ded50 328 SUPERFAMILY SSF56672 43 273 2.0E-27 T 29-03-2018 THSYN_RS12545 e4eefc72efd58d6e1efd88a5714ded50 328 Gene3D G3DSA:3.30.70.270 83 266 2.3E-17 T 29-03-2018 THSYN_RS32490 54bf873de42da25c1a4d7f9b5acf3d77 486 SUPERFAMILY SSF51905 2 72 2.46E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS32490 54bf873de42da25c1a4d7f9b5acf3d77 486 SUPERFAMILY SSF51905 219 394 2.46E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS32490 54bf873de42da25c1a4d7f9b5acf3d77 486 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 317 9.4E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS32490 54bf873de42da25c1a4d7f9b5acf3d77 486 Gene3D G3DSA:3.50.50.60 1 141 3.0E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS32490 54bf873de42da25c1a4d7f9b5acf3d77 486 SUPERFAMILY SSF51905 2 197 6.58E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS32490 54bf873de42da25c1a4d7f9b5acf3d77 486 Gene3D G3DSA:3.50.50.60 142 285 1.8E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS25630 3df29b145052c999fb0b6f2d16817646 222 SUPERFAMILY SSF56281 3 209 6.81E-57 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS25630 3df29b145052c999fb0b6f2d16817646 222 Pfam PF00753 Metallo-beta-lactamase superfamily 9 192 9.5E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS25630 3df29b145052c999fb0b6f2d16817646 222 Gene3D G3DSA:3.60.15.10 1 215 1.8E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS25630 3df29b145052c999fb0b6f2d16817646 222 SMART SM00849 12 192 2.7E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS16105 16160a0e0b3a412d3fb5e74d22371215 304 Gene3D G3DSA:2.40.320.10 29 239 5.5E-4 T 29-03-2018 THSYN_RS21765 4d4432cb37e8063dd60a4460db93af84 402 Pfam PF07075 Protein of unknown function (DUF1343) 24 401 5.0E-102 T 29-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 THSYN_RS21765 4d4432cb37e8063dd60a4460db93af84 402 PIRSF PIRSF016719 1 400 1.9E-94 T 29-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 THSYN_RS17770 a03d9974d5ad99f1be626eb883b34838 420 Pfam PF06114 IrrE N-terminal-like domain 190 317 1.3E-18 T 29-03-2018 IPR010359 IrrE N-terminal-like domain THSYN_RS17770 a03d9974d5ad99f1be626eb883b34838 420 SUPERFAMILY SSF47413 32 96 2.39E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS17770 a03d9974d5ad99f1be626eb883b34838 420 Gene3D G3DSA:1.10.260.40 52 100 1.2E-14 T 29-03-2018 THSYN_RS17770 a03d9974d5ad99f1be626eb883b34838 420 Gene3D G3DSA:1.10.10.60 11 51 0.0022 T 29-03-2018 THSYN_RS17770 a03d9974d5ad99f1be626eb883b34838 420 SMART SM00530 38 93 1.6E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS17770 a03d9974d5ad99f1be626eb883b34838 420 Pfam PF13560 Helix-turn-helix domain 34 92 1.2E-11 T 29-03-2018 THSYN_RS12110 dbaf34dbcc966b6cddb536c94bd24c6b 513 SMART SM00327 89 267 5.6E-15 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS12110 dbaf34dbcc966b6cddb536c94bd24c6b 513 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 421 511 1.2E-16 T 29-03-2018 IPR032030 YscD, cytoplasmic domain THSYN_RS12110 dbaf34dbcc966b6cddb536c94bd24c6b 513 Gene3D G3DSA:3.40.50.410 85 275 1.2E-23 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS12110 dbaf34dbcc966b6cddb536c94bd24c6b 513 SUPERFAMILY SSF53300 93 234 7.57E-22 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS12110 dbaf34dbcc966b6cddb536c94bd24c6b 513 SUPERFAMILY SSF49879 387 511 2.3E-25 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 THSYN_RS12110 dbaf34dbcc966b6cddb536c94bd24c6b 513 Gene3D G3DSA:2.60.200.20 395 513 4.1E-24 T 29-03-2018 THSYN_RS12110 dbaf34dbcc966b6cddb536c94bd24c6b 513 Pfam PF00092 von Willebrand factor type A domain 94 231 1.2E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS12110 dbaf34dbcc966b6cddb536c94bd24c6b 513 SMART SM00240 438 490 2.7E-10 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THSYN_RS17830 74b233f678aea73593cec7bd67d29363 126 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 122 6.0E-42 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THSYN_RS17830 74b233f678aea73593cec7bd67d29363 126 Gene3D G3DSA:2.40.40.20 1 117 6.9E-50 T 29-03-2018 THSYN_RS17830 74b233f678aea73593cec7bd67d29363 126 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 125 3.6E-49 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THSYN_RS17830 74b233f678aea73593cec7bd67d29363 126 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 68.923 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THSYN_RS17830 74b233f678aea73593cec7bd67d29363 126 PIRSF PIRSF006246 1 125 1.6E-49 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THSYN_RS17830 74b233f678aea73593cec7bd67d29363 126 SUPERFAMILY SSF50692 1 116 3.23E-46 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain THSYN_RS17830 74b233f678aea73593cec7bd67d29363 126 Pfam PF02261 Aspartate decarboxylase 1 114 6.6E-48 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THSYN_RS27170 8ba1746f0678084b1b525ce5a7e88daa 297 SMART SM00267 120 296 2.1E-63 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS27170 8ba1746f0678084b1b525ce5a7e88daa 297 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 128 295 1.5E-45 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS27170 8ba1746f0678084b1b525ce5a7e88daa 297 SUPERFAMILY SSF55073 136 294 9.42E-46 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS27170 8ba1746f0678084b1b525ce5a7e88daa 297 Pfam PF00072 Response regulator receiver domain 3 111 1.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS27170 8ba1746f0678084b1b525ce5a7e88daa 297 Gene3D G3DSA:3.30.70.270 129 297 1.5E-51 T 29-03-2018 THSYN_RS27170 8ba1746f0678084b1b525ce5a7e88daa 297 Gene3D G3DSA:3.40.50.2300 1 128 1.8E-37 T 29-03-2018 THSYN_RS27170 8ba1746f0678084b1b525ce5a7e88daa 297 SUPERFAMILY SSF52172 1 126 5.55E-41 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS27170 8ba1746f0678084b1b525ce5a7e88daa 297 SMART SM00448 1 114 5.6E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS27170 8ba1746f0678084b1b525ce5a7e88daa 297 Pfam PF00990 Diguanylate cyclase, GGDEF domain 131 292 3.5E-45 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS08200 c6333e6ca23fee2bc2d9aa5f39235676 226 Gene3D G3DSA:3.40.50.2300 1 124 4.2E-32 T 29-03-2018 THSYN_RS08200 c6333e6ca23fee2bc2d9aa5f39235676 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 9.3E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS08200 c6333e6ca23fee2bc2d9aa5f39235676 226 Pfam PF00072 Response regulator receiver domain 3 112 7.6E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08200 c6333e6ca23fee2bc2d9aa5f39235676 226 SMART SM00448 1 112 9.0E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08200 c6333e6ca23fee2bc2d9aa5f39235676 226 SMART SM00862 146 221 1.4E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS08200 c6333e6ca23fee2bc2d9aa5f39235676 226 SUPERFAMILY SSF52172 1 181 3.73E-37 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS08200 c6333e6ca23fee2bc2d9aa5f39235676 226 Gene3D G3DSA:1.10.10.10 125 226 4.3E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS24675 22f29a465e168e06b6501a70ccd94b74 683 Pfam PF00654 Voltage gated chloride channel 311 651 7.1E-85 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 THSYN_RS24675 22f29a465e168e06b6501a70ccd94b74 683 Gene3D G3DSA:1.10.3080.10 249 663 1.8E-78 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 THSYN_RS24675 22f29a465e168e06b6501a70ccd94b74 683 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 32 107 1.4E-17 T 29-03-2018 IPR020012 Motility protein FimV, N-terminal THSYN_RS24675 22f29a465e168e06b6501a70ccd94b74 683 SUPERFAMILY SSF81340 248 652 8.37E-94 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 THSYN_RS24675 22f29a465e168e06b6501a70ccd94b74 683 Gene3D G3DSA:3.10.350.10 21 84 9.4E-6 T 29-03-2018 THSYN_RS11605 6fc0ddb4c57cd8ebd6041c36aa0c32fd 233 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 208 28.216 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 THSYN_RS11605 6fc0ddb4c57cd8ebd6041c36aa0c32fd 233 Gene3D G3DSA:3.40.50.300 1 218 1.2E-59 T 29-03-2018 THSYN_RS11605 6fc0ddb4c57cd8ebd6041c36aa0c32fd 233 Pfam PF13500 AAA domain 3 207 1.1E-37 T 29-03-2018 THSYN_RS11605 6fc0ddb4c57cd8ebd6041c36aa0c32fd 233 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 5 175 2.7E-46 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 THSYN_RS11605 6fc0ddb4c57cd8ebd6041c36aa0c32fd 233 PIRSF PIRSF006755 1 228 5.5E-68 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 THSYN_RS11605 6fc0ddb4c57cd8ebd6041c36aa0c32fd 233 SUPERFAMILY SSF52540 1 216 3.72E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12685 05de6f022007996864f0f48fbf27f252 447 Gene3D G3DSA:1.10.3290.10 17 273 4.0E-53 T 29-03-2018 IPR003812 Fido domain THSYN_RS12685 05de6f022007996864f0f48fbf27f252 447 Pfam PF02661 Fic/DOC family 113 207 7.9E-21 T 29-03-2018 IPR003812 Fido domain THSYN_RS12685 05de6f022007996864f0f48fbf27f252 447 SUPERFAMILY SSF140931 92 257 4.58E-34 T 29-03-2018 IPR003812 Fido domain THSYN_RS10775 383339ceb102f978764bc8252be6c7c9 195 SUPERFAMILY SSF53474 64 190 4.79E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS10775 383339ceb102f978764bc8252be6c7c9 195 Gene3D G3DSA:3.40.50.1820 33 192 2.4E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS10775 383339ceb102f978764bc8252be6c7c9 195 Pfam PF00450 Serine carboxypeptidase 50 160 8.6E-17 T 29-03-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 THSYN_RS17260 14ca3ed7d68a2ddcbc4dea84f2380862 431 Gene3D G3DSA:3.90.1580.10 146 194 1.4E-4 T 29-03-2018 THSYN_RS17260 14ca3ed7d68a2ddcbc4dea84f2380862 431 Pfam PF03781 Sulfatase-modifying factor enzyme 1 159 385 1.6E-38 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS17260 14ca3ed7d68a2ddcbc4dea84f2380862 431 Gene3D G3DSA:3.90.1580.10 195 383 1.3E-53 T 29-03-2018 THSYN_RS17260 14ca3ed7d68a2ddcbc4dea84f2380862 431 SUPERFAMILY SSF56436 151 235 5.42E-58 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS17260 14ca3ed7d68a2ddcbc4dea84f2380862 431 SUPERFAMILY SSF56436 264 387 5.42E-58 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 SUPERFAMILY SSF82866 822 1057 3.92E-43 T 29-03-2018 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 Gene3D G3DSA:3.30.2090.10 184 269 1.4E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 SUPERFAMILY SSF82714 739 824 1.02E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 Gene3D G3DSA:3.30.70.1430 43 138 1.3E-19 T 29-03-2018 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 Gene3D G3DSA:3.30.70.1430 583 682 6.7E-5 T 29-03-2018 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1059 0.0 T 29-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 SUPERFAMILY SSF82693 137 184 7.06E-21 T 29-03-2018 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 SUPERFAMILY SSF82693 270 326 7.06E-21 T 29-03-2018 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 SUPERFAMILY SSF82866 292 502 3.01E-37 T 29-03-2018 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 Gene3D G3DSA:1.20.1640.10 285 512 1.3E-37 T 29-03-2018 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 6.1E-19 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 6.1E-19 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 PRINTS PR00702 Acriflavin resistance protein family signature 359 380 6.1E-19 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 PRINTS PR00702 Acriflavin resistance protein family signature 332 355 6.1E-19 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 SUPERFAMILY SSF82714 185 267 4.19E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 Pfam PF00873 AcrB/AcrD/AcrF family 6 1054 6.6E-225 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 Gene3D G3DSA:1.20.1640.10 828 1057 1.8E-30 T 29-03-2018 THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 Gene3D G3DSA:3.30.2090.10 738 826 4.3E-19 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS05455 02db4dc39d3ddb5b8d7615bee9ac4b1c 1070 SUPERFAMILY SSF82693 44 127 9.16E-20 T 29-03-2018 THSYN_RS01150 c11ccde9f8507400d383402e985893a0 448 Pfam PF04403 Paraquat-inducible protein A 251 407 2.8E-58 T 29-03-2018 IPR007498 Paraquat-inducible protein A THSYN_RS01150 c11ccde9f8507400d383402e985893a0 448 Pfam PF04403 Paraquat-inducible protein A 43 197 1.0E-46 T 29-03-2018 IPR007498 Paraquat-inducible protein A THSYN_RS01150 c11ccde9f8507400d383402e985893a0 448 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 4 406 9.5E-89 T 29-03-2018 IPR005219 Conserved hypothetical protein CHP00155 THSYN_RS08850 c0774f4971067665413213b277f8337e 265 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 63 254 7.2E-63 T 29-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO THSYN_RS08850 c0774f4971067665413213b277f8337e 265 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 83 236 2.0E-64 T 29-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO THSYN_RS08850 c0774f4971067665413213b277f8337e 265 SUPERFAMILY SSF46626 221 248 4.31E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS08850 c0774f4971067665413213b277f8337e 265 SUPERFAMILY SSF46626 24 42 4.31E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS08850 c0774f4971067665413213b277f8337e 265 SUPERFAMILY SSF46626 87 194 4.31E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS08850 c0774f4971067665413213b277f8337e 265 Gene3D G3DSA:1.10.760.10 78 264 2.4E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS03865 5eace25beda76953b03a7e9999897183 221 SUPERFAMILY SSF51391 5 211 2.35E-60 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THSYN_RS03865 5eace25beda76953b03a7e9999897183 221 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 6 212 25.89 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THSYN_RS03865 5eace25beda76953b03a7e9999897183 221 Pfam PF02581 Thiamine monophosphate synthase 8 194 2.0E-54 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THSYN_RS03865 5eace25beda76953b03a7e9999897183 221 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 8 205 3.4E-56 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THSYN_RS03865 5eace25beda76953b03a7e9999897183 221 Gene3D G3DSA:3.20.20.70 2 212 9.1E-45 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS20655 96dd17efb2602c8cb3477fe144435f83 90 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 70 1.1E-19 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS20655 96dd17efb2602c8cb3477fe144435f83 90 Pfam PF01455 HupF/HypC family 1 67 1.8E-24 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS20655 96dd17efb2602c8cb3477fe144435f83 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 19 35 4.1E-16 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS20655 96dd17efb2602c8cb3477fe144435f83 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 4.1E-16 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS20655 96dd17efb2602c8cb3477fe144435f83 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 40 56 4.1E-16 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS20655 96dd17efb2602c8cb3477fe144435f83 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 58 70 4.1E-16 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THSYN_RS20655 96dd17efb2602c8cb3477fe144435f83 90 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 29-03-2018 IPR019812 Hydrogenase assembly chaperone, conserved site THSYN_RS20655 96dd17efb2602c8cb3477fe144435f83 90 SUPERFAMILY SSF159127 1 76 5.1E-22 T 29-03-2018 THSYN_RS16150 a0cfa7d5736b0f0935d8723716079ff4 282 Pfam PF13676 TIR domain 11 118 8.4E-12 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS16150 a0cfa7d5736b0f0935d8723716079ff4 282 SUPERFAMILY SSF49464 206 271 1.22E-8 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain THSYN_RS16150 a0cfa7d5736b0f0935d8723716079ff4 282 Gene3D G3DSA:3.40.50.10140 5 122 2.3E-6 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS16150 a0cfa7d5736b0f0935d8723716079ff4 282 SUPERFAMILY SSF52200 5 116 8.5E-7 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS16150 a0cfa7d5736b0f0935d8723716079ff4 282 Gene3D G3DSA:2.60.40.1120 206 277 6.8E-8 T 29-03-2018 THSYN_RS16150 a0cfa7d5736b0f0935d8723716079ff4 282 Pfam PF13620 Carboxypeptidase regulatory-like domain 206 268 3.2E-7 T 29-03-2018 THSYN_RS01520 cf15d4171023530224bfba52a5e15f71 185 SUPERFAMILY SSF52980 5 183 4.08E-28 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS01520 cf15d4171023530224bfba52a5e15f71 185 Gene3D G3DSA:3.90.1570.10 2 183 2.3E-29 T 29-03-2018 THSYN_RS01520 cf15d4171023530224bfba52a5e15f71 185 Pfam PF05685 Putative restriction endonuclease 10 155 3.9E-20 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS02815 be691a88aa3c890cd16189c1ea32439c 190 Pfam PF13707 RloB-like protein 55 158 7.2E-19 T 29-03-2018 IPR025591 RloB-like protein THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 SUPERFAMILY SSF52218 60 207 1.7E-43 T 29-03-2018 IPR029039 Flavoprotein-like domain THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 Gene3D G3DSA:3.40.50.360 48 217 1.3E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 Pfam PF00667 FAD binding domain 362 425 4.2E-9 T 29-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 PRINTS PR00369 Flavodoxin signature 110 121 2.9E-12 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 PRINTS PR00369 Flavodoxin signature 142 152 2.9E-12 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 PRINTS PR00369 Flavodoxin signature 62 75 2.9E-12 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 PRINTS PR00369 Flavodoxin signature 166 185 2.9E-12 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 Pfam PF00258 Flavodoxin 63 179 1.6E-29 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 PIRSF PIRSF000207 1 599 1.6E-205 T 29-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 Pfam PF00175 Oxidoreductase NAD-binding domain 458 563 1.2E-17 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 Gene3D G3DSA:2.40.30.10 227 439 4.4E-37 T 29-03-2018 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 526 542 8.1E-21 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 271 281 8.1E-21 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 482 491 8.1E-21 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 387 394 8.1E-21 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 457 476 8.1E-21 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 549 557 8.1E-21 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 SUPERFAMILY SSF63380 234 447 1.29E-56 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 SUPERFAMILY SSF52343 445 599 7.6E-47 T 29-03-2018 THSYN_RS27870 c75a64c76e170d7adc0bf15b6bb84f60 599 Gene3D G3DSA:3.40.50.80 443 598 4.3E-35 T 29-03-2018 THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 Pfam PF00330 Aconitase family (aconitate hydratase) 471 817 2.0E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 ProSitePatterns PS01244 Aconitase family signature 2. 763 776 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 Gene3D G3DSA:3.30.499.10 405 524 8.2E-10 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 PIRSF PIRSF036687 1 861 0.0 T 29-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 Gene3D G3DSA:3.20.19.10 162 362 5.8E-31 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 SUPERFAMILY SSF52016 161 371 6.54E-62 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 855 0.0 T 29-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 Pfam PF11791 Aconitate B N-terminal domain 4 156 9.3E-63 T 29-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 Gene3D G3DSA:3.30.499.10 686 862 2.7E-49 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 382 1.1E-91 T 29-03-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 ProSitePatterns PS00450 Aconitase family signature 1. 705 722 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 SUPERFAMILY SSF74778 1 160 7.06E-67 T 29-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 SUPERFAMILY SSF53732 379 855 1.96E-143 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS10500 5fa0abf539cda72808aee58b44f58993 862 Gene3D G3DSA:3.40.1060.10 525 685 4.7E-28 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS25125 3671c5816d46f3a84e2c3b31b1932f0a 261 Pfam PF05050 Methyltransferase FkbM domain 61 204 4.3E-14 T 29-03-2018 IPR006342 Methyltransferase FkbM THSYN_RS25125 3671c5816d46f3a84e2c3b31b1932f0a 261 Gene3D G3DSA:3.40.50.150 40 223 1.4E-26 T 29-03-2018 THSYN_RS25125 3671c5816d46f3a84e2c3b31b1932f0a 261 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 58 196 5.4E-26 T 29-03-2018 IPR006342 Methyltransferase FkbM THSYN_RS25125 3671c5816d46f3a84e2c3b31b1932f0a 261 SUPERFAMILY SSF53335 46 232 1.96E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS16700 fe1280b1a04e9d60337f9d185063187d 372 Gene3D G3DSA:3.40.430.10 119 362 2.1E-71 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 THSYN_RS16700 fe1280b1a04e9d60337f9d185063187d 372 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 44 82 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 THSYN_RS16700 fe1280b1a04e9d60337f9d185063187d 372 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 140 361 4.6E-60 T 29-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 THSYN_RS16700 fe1280b1a04e9d60337f9d185063187d 372 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 1 359 3.0E-113 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 THSYN_RS16700 fe1280b1a04e9d60337f9d185063187d 372 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 93 1.7E-17 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain THSYN_RS16700 fe1280b1a04e9d60337f9d185063187d 372 SUPERFAMILY SSF53927 1 138 1.84E-45 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 THSYN_RS16700 fe1280b1a04e9d60337f9d185063187d 372 Gene3D G3DSA:3.40.140.10 1 118 1.9E-30 T 29-03-2018 THSYN_RS16700 fe1280b1a04e9d60337f9d185063187d 372 SUPERFAMILY SSF53597 139 360 1.3E-57 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 THSYN_RS16700 fe1280b1a04e9d60337f9d185063187d 372 Pfam PF01872 RibD C-terminal domain 141 357 4.0E-51 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 THSYN_RS16700 fe1280b1a04e9d60337f9d185063187d 372 PIRSF PIRSF006769 1 363 4.9E-124 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 THSYN_RS11460 584c4658b816d50f54d3537bc7906bbe 506 Pfam PF00171 Aldehyde dehydrogenase family 27 493 1.3E-162 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THSYN_RS11460 584c4658b816d50f54d3537bc7906bbe 506 Gene3D G3DSA:3.40.309.10 280 480 3.1E-64 T 29-03-2018 THSYN_RS11460 584c4658b816d50f54d3537bc7906bbe 506 Gene3D G3DSA:3.40.605.10 7 279 2.7E-94 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THSYN_RS11460 584c4658b816d50f54d3537bc7906bbe 506 SUPERFAMILY SSF53720 13 498 1.28E-160 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THSYN_RS11460 584c4658b816d50f54d3537bc7906bbe 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THSYN_RS11460 584c4658b816d50f54d3537bc7906bbe 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THSYN_RS24960 2c33f8970f416dea4f3b1dc71690d24a 297 Gene3D G3DSA:3.40.630.30 48 215 5.2E-19 T 29-03-2018 THSYN_RS24960 2c33f8970f416dea4f3b1dc71690d24a 297 Pfam PF00583 Acetyltransferase (GNAT) family 92 191 5.6E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS24960 2c33f8970f416dea4f3b1dc71690d24a 297 SUPERFAMILY SSF55729 22 194 1.95E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 Pfam PF00515 Tetratricopeptide repeat 78 111 3.6E-9 T 29-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 Gene3D G3DSA:3.40.50.2000 445 633 2.8E-28 T 29-03-2018 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 SUPERFAMILY SSF48452 9 231 1.9E-45 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 Gene3D G3DSA:1.20.120.420 180 246 3.9E-9 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 Gene3D G3DSA:1.25.40.10 2 84 6.0E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 Pfam PF13414 TPR repeat 119 159 5.1E-12 T 29-03-2018 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 SMART SM00028 112 145 1.5E-6 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 SMART SM00028 180 213 0.0012 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 SMART SM00028 44 77 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 SMART SM00028 10 43 0.035 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 SMART SM00028 78 111 1.9E-7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 SMART SM00028 146 179 2.4E-6 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 Gene3D G3DSA:1.10.8.10 146 155 4.7E-5 T 29-03-2018 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 Gene3D G3DSA:1.20.58.280 156 179 6.1E-13 T 29-03-2018 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 Gene3D G3DSA:1.20.58.280 121 145 2.9E-13 T 29-03-2018 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 Gene3D G3DSA:1.25.40.10 85 120 6.2E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 Pfam PF13844 Glycosyl transferase family 41 296 443 1.8E-39 T 29-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 Pfam PF13844 Glycosyl transferase family 41 458 650 3.9E-46 T 29-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 THSYN_RS29095 bc09ef5f81dab3a5b312be1174afa13c 665 Pfam PF13432 Tetratricopeptide repeat 14 76 1.1E-5 T 29-03-2018 THSYN_RS24225 0419a07c152d776945c0994c7a4579c3 226 SUPERFAMILY SSF103088 107 222 6.67E-36 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS24225 0419a07c152d776945c0994c7a4579c3 226 Gene3D G3DSA:3.30.1330.60 75 224 2.2E-38 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS24225 0419a07c152d776945c0994c7a4579c3 226 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 182 201 1.0E-7 T 29-03-2018 THSYN_RS24225 0419a07c152d776945c0994c7a4579c3 226 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 202 222 1.0E-7 T 29-03-2018 THSYN_RS24225 0419a07c152d776945c0994c7a4579c3 226 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 164 181 1.0E-7 T 29-03-2018 THSYN_RS24225 0419a07c152d776945c0994c7a4579c3 226 PRINTS PR01021 OMPA domain signature 149 164 4.7E-13 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS24225 0419a07c152d776945c0994c7a4579c3 226 PRINTS PR01021 OMPA domain signature 164 180 4.7E-13 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS24225 0419a07c152d776945c0994c7a4579c3 226 PRINTS PR01021 OMPA domain signature 119 141 4.7E-13 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS24225 0419a07c152d776945c0994c7a4579c3 226 Pfam PF13488 Glycine zipper 38 83 6.5E-9 T 29-03-2018 THSYN_RS24225 0419a07c152d776945c0994c7a4579c3 226 Pfam PF00691 OmpA family 118 213 2.2E-22 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS13575 03781b021105d437ba8e8a3412d55be1 72 Pfam PF10387 Protein of unknown function (DUF2442) 9 70 5.5E-7 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS13575 03781b021105d437ba8e8a3412d55be1 72 SUPERFAMILY SSF143880 6 69 1.31E-12 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS13575 03781b021105d437ba8e8a3412d55be1 72 Gene3D G3DSA:3.30.2020.10 2 72 2.6E-13 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS11660 559a0bd3fd4a67a62ddb395e6c1cf911 190 SUPERFAMILY SSF52980 12 190 5.31E-20 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS11660 559a0bd3fd4a67a62ddb395e6c1cf911 190 Gene3D G3DSA:3.90.1570.10 8 190 4.4E-31 T 29-03-2018 THSYN_RS11660 559a0bd3fd4a67a62ddb395e6c1cf911 190 Pfam PF05685 Putative restriction endonuclease 19 180 6.8E-29 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS17440 b0afe0074cda1e9b8baa9f5d4baf36da 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 29-03-2018 IPR001455 TusA-like domain THSYN_RS17440 b0afe0074cda1e9b8baa9f5d4baf36da 75 Pfam PF01206 Sulfurtransferase TusA 6 74 2.5E-24 T 29-03-2018 IPR001455 TusA-like domain THSYN_RS17440 b0afe0074cda1e9b8baa9f5d4baf36da 75 SUPERFAMILY SSF64307 3 75 4.45E-24 T 29-03-2018 IPR001455 TusA-like domain THSYN_RS17440 b0afe0074cda1e9b8baa9f5d4baf36da 75 Gene3D G3DSA:3.30.110.40 1 75 2.1E-28 T 29-03-2018 IPR001455 TusA-like domain THSYN_RS16720 63d9cb303ab8b99dd9250bf004d523cb 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THSYN_RS16720 63d9cb303ab8b99dd9250bf004d523cb 236 Pfam PF00106 short chain dehydrogenase 14 208 5.0E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16720 63d9cb303ab8b99dd9250bf004d523cb 236 SUPERFAMILY SSF51735 12 231 3.71E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS16720 63d9cb303ab8b99dd9250bf004d523cb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 6.9E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16720 63d9cb303ab8b99dd9250bf004d523cb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 6.9E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16720 63d9cb303ab8b99dd9250bf004d523cb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 6.9E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16720 63d9cb303ab8b99dd9250bf004d523cb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 6.9E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS16720 63d9cb303ab8b99dd9250bf004d523cb 236 Gene3D G3DSA:3.40.50.720 2 208 2.8E-49 T 29-03-2018 THSYN_RS21730 c7361696bd0c84f23f28a03684582d3b 282 Gene3D G3DSA:3.40.50.1400 1 139 2.0E-16 T 29-03-2018 THSYN_RS21730 c7361696bd0c84f23f28a03684582d3b 282 SUPERFAMILY SSF53800 1 270 1.83E-12 T 29-03-2018 THSYN_RS21730 c7361696bd0c84f23f28a03684582d3b 282 Gene3D G3DSA:3.40.50.1400 140 281 2.6E-14 T 29-03-2018 THSYN_RS13255 340b41bce4843485d6e275ffb61475b2 148 Pfam PF01724 Domain of unknown function DUF29 7 144 1.7E-47 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS15485 77a93dcc1ea673aa11a324913f9f5baf 765 Gene3D G3DSA:2.120.10.30 57 478 3.2E-8 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS15485 77a93dcc1ea673aa11a324913f9f5baf 765 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 506 614 6.7E-19 T 29-03-2018 IPR011748 Uncharacterised protein family, phage tail-like THSYN_RS15485 77a93dcc1ea673aa11a324913f9f5baf 765 Gene3D G3DSA:2.160.10.10 608 738 0.0018 T 29-03-2018 THSYN_RS15485 77a93dcc1ea673aa11a324913f9f5baf 765 SUPERFAMILY SSF101898 59 264 3.4E-10 T 29-03-2018 THSYN_RS15485 77a93dcc1ea673aa11a324913f9f5baf 765 Pfam PF09684 Phage tail protein (Tail_P2_I) 530 658 4.2E-12 T 29-03-2018 IPR006521 Tail protein I THSYN_RS26075 6d3bc864b3acb2b09ab6e4e093370dc5 334 SUPERFAMILY SSF46785 3 76 7.89E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26075 6d3bc864b3acb2b09ab6e4e093370dc5 334 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 325 26.129 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 THSYN_RS26075 6d3bc864b3acb2b09ab6e4e093370dc5 334 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 331 3.6E-98 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 THSYN_RS26075 6d3bc864b3acb2b09ab6e4e093370dc5 334 Gene3D G3DSA:3.30.450.40 177 334 4.6E-45 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS26075 6d3bc864b3acb2b09ab6e4e093370dc5 334 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 3 67 1.6E-5 T 29-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 THSYN_RS26075 6d3bc864b3acb2b09ab6e4e093370dc5 334 SUPERFAMILY SSF55781 65 333 2.16E-61 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS26075 6d3bc864b3acb2b09ab6e4e093370dc5 334 PIRSF PIRSF005485 1 334 1.8E-104 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 THSYN_RS26075 6d3bc864b3acb2b09ab6e4e093370dc5 334 Gene3D G3DSA:1.10.10.10 1 79 1.8E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26075 6d3bc864b3acb2b09ab6e4e093370dc5 334 Pfam PF01628 HrcA protein C terminal domain 98 318 4.3E-60 T 29-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 THSYN_RS15110 9890d1a46c1f35a4ce8dc0cf1a3641a3 464 Gene3D G3DSA:3.40.720.10 1 257 2.9E-17 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS15110 9890d1a46c1f35a4ce8dc0cf1a3641a3 464 SUPERFAMILY SSF53649 3 411 1.76E-70 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS15110 9890d1a46c1f35a4ce8dc0cf1a3641a3 464 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 9 375 8.7E-56 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 THSYN_RS15110 9890d1a46c1f35a4ce8dc0cf1a3641a3 464 Gene3D G3DSA:3.30.1360.110 275 358 5.6E-20 T 29-03-2018 IPR023116 Phosphonoacetate hydrolase, insert domain KEGG: 00440+3.11.1.2 THSYN_RS26525 8cb94e27e666cce13fc86c254df77406 631 PIRSF PIRSF001589 2 628 3.9E-66 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS26525 8cb94e27e666cce13fc86c254df77406 631 Pfam PF00733 Asparagine synthase 243 549 6.5E-34 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THSYN_RS26525 8cb94e27e666cce13fc86c254df77406 631 Gene3D G3DSA:3.40.50.620 222 629 3.2E-40 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS26525 8cb94e27e666cce13fc86c254df77406 631 SUPERFAMILY SSF56235 3 224 1.2E-33 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS26525 8cb94e27e666cce13fc86c254df77406 631 Gene3D G3DSA:3.60.20.10 1 221 3.4E-28 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS26525 8cb94e27e666cce13fc86c254df77406 631 SUPERFAMILY SSF52402 230 387 7.82E-38 T 29-03-2018 THSYN_RS26525 8cb94e27e666cce13fc86c254df77406 631 SUPERFAMILY SSF52402 474 551 7.82E-38 T 29-03-2018 THSYN_RS26525 8cb94e27e666cce13fc86c254df77406 631 Pfam PF13537 Glutamine amidotransferase domain 56 166 9.1E-18 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 SMART SM00086 353 395 2.6E-8 T 29-03-2018 IPR001610 PAC motif THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 SMART SM00086 231 273 4.3E-4 T 29-03-2018 IPR001610 PAC motif THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 Pfam PF00072 Response regulator receiver domain 18 127 2.8E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 SMART SM00267 395 567 2.5E-68 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 SMART SM00091 145 224 0.0071 T 29-03-2018 IPR000014 PAS domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 SMART SM00091 281 347 2.0E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 SUPERFAMILY SSF141868 582 829 4.84E-88 T 29-03-2018 IPR001633 EAL domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 Pfam PF00563 EAL domain 584 817 1.1E-71 T 29-03-2018 IPR001633 EAL domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 SUPERFAMILY SSF55785 133 271 7.33E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 Gene3D G3DSA:3.30.70.270 402 570 1.9E-61 T 29-03-2018 THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 SUPERFAMILY SSF55785 286 393 4.89E-30 T 29-03-2018 IPR000014 PAS domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 PIRSF PIRSF005925 273 399 8.5E-13 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 PIRSF PIRSF005925 394 833 4.9E-143 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 PIRSF PIRSF005925 152 286 2.7E-6 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 SUPERFAMILY SSF52172 15 151 6.12E-36 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 Gene3D G3DSA:3.20.20.450 571 833 8.3E-98 T 29-03-2018 IPR001633 EAL domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 Gene3D G3DSA:3.30.450.20 137 279 1.2E-25 T 29-03-2018 THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 Gene3D G3DSA:3.40.50.10600 280 401 4.3E-28 T 29-03-2018 THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 171 279 9.8E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 284 401 2.0E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 403 565 1.2E-46 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 Gene3D G3DSA:3.40.50.2300 2 136 2.2E-34 T 29-03-2018 THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 SUPERFAMILY SSF55073 411 567 4.94E-51 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 SMART SM00052 577 822 3.3E-116 T 29-03-2018 IPR001633 EAL domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 Pfam PF13426 PAS domain 292 394 1.3E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 Pfam PF13426 PAS domain 174 272 5.0E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 SMART SM00448 16 127 1.1E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS17545 eb5bcf925e22c2f5e4a79f6606c2a847 835 Pfam PF00990 Diguanylate cyclase, GGDEF domain 406 563 3.4E-49 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS18595 e8a0af6e28bfd80d7d1a86ce6dfc4950 752 Pfam PF00672 HAMP domain 425 470 3.8E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS18595 e8a0af6e28bfd80d7d1a86ce6dfc4950 752 SUPERFAMILY SSF58104 443 752 2.88E-55 T 29-03-2018 THSYN_RS18595 e8a0af6e28bfd80d7d1a86ce6dfc4950 752 SMART SM00304 423 475 3.0E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS18595 e8a0af6e28bfd80d7d1a86ce6dfc4950 752 SMART SM00304 476 528 110.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS18595 e8a0af6e28bfd80d7d1a86ce6dfc4950 752 SMART SM00283 490 751 1.8E-46 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THSYN_RS18595 e8a0af6e28bfd80d7d1a86ce6dfc4950 752 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 564 715 4.4E-31 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THSYN_RS18595 e8a0af6e28bfd80d7d1a86ce6dfc4950 752 Gene3D G3DSA:1.10.287.950 289 525 3.8E-6 T 29-03-2018 THSYN_RS18595 e8a0af6e28bfd80d7d1a86ce6dfc4950 752 Gene3D G3DSA:1.10.287.950 526 752 1.5E-39 T 29-03-2018 THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 Pfam PF00512 His Kinase A (phospho-acceptor) domain 226 289 3.8E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 Gene3D G3DSA:3.30.565.10 298 453 5.3E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 SMART SM00387 337 447 4.4E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 Gene3D G3DSA:1.20.5.1040 127 172 0.0023 T 29-03-2018 THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 Gene3D G3DSA:1.20.5.1040 2 55 2.5E-7 T 29-03-2018 THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 SUPERFAMILY SSF47384 208 288 7.65E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 343 444 3.8E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 Pfam PF08521 Two-component sensor kinase N-terminal 18 144 8.7E-9 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 424 2.1E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 402 2.1E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 388 2.1E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 Gene3D G3DSA:1.10.287.130 215 286 1.6E-15 T 29-03-2018 THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 SMART SM00388 225 290 4.7E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS11690 07f4d1629dfdd890e02968f3c559be03 455 SUPERFAMILY SSF55874 280 445 5.11E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS26675 d80ce4fcd4f771755d990ea32dabd51a 357 Gene3D G3DSA:3.30.460.20 46 169 8.9E-6 T 29-03-2018 THSYN_RS26675 d80ce4fcd4f771755d990ea32dabd51a 357 SUPERFAMILY SSF144083 292 355 8.89E-21 T 29-03-2018 THSYN_RS26675 d80ce4fcd4f771755d990ea32dabd51a 357 Pfam PF01544 CorA-like Mg2+ transporter protein 69 353 1.7E-46 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 THSYN_RS26675 d80ce4fcd4f771755d990ea32dabd51a 357 Gene3D G3DSA:1.20.58.340 290 357 3.4E-20 T 29-03-2018 THSYN_RS26675 d80ce4fcd4f771755d990ea32dabd51a 357 Gene3D G3DSA:1.20.58.340 173 289 6.5E-8 T 29-03-2018 THSYN_RS26675 d80ce4fcd4f771755d990ea32dabd51a 357 SUPERFAMILY SSF143865 38 296 4.58E-28 T 29-03-2018 THSYN_RS26675 d80ce4fcd4f771755d990ea32dabd51a 357 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 65 357 9.9E-65 T 29-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 THSYN_RS14290 bfbd467d4e69d25dda3ba60d160e8bd7 327 Pfam PF13353 4Fe-4S single cluster domain 21 89 1.3E-4 T 29-03-2018 THSYN_RS14290 bfbd467d4e69d25dda3ba60d160e8bd7 327 Pfam PF06463 Molybdenum Cofactor Synthesis C 185 311 3.2E-38 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 THSYN_RS14290 bfbd467d4e69d25dda3ba60d160e8bd7 327 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 5 327 4.4E-107 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 THSYN_RS14290 bfbd467d4e69d25dda3ba60d160e8bd7 327 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 327 37.82 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 THSYN_RS14290 bfbd467d4e69d25dda3ba60d160e8bd7 327 SUPERFAMILY SSF102114 4 280 3.66E-71 T 29-03-2018 THSYN_RS14290 bfbd467d4e69d25dda3ba60d160e8bd7 327 SMART SM00729 14 220 8.3E-9 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS14290 bfbd467d4e69d25dda3ba60d160e8bd7 327 Gene3D G3DSA:3.20.20.70 1 327 6.3E-78 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS14290 bfbd467d4e69d25dda3ba60d160e8bd7 327 Pfam PF04055 Radical SAM superfamily 19 178 2.5E-25 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS14290 bfbd467d4e69d25dda3ba60d160e8bd7 327 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 THSYN_RS03375 30d62e9f32fcbdb023929921658bf37f 748 Pfam PF01103 Surface antigen 506 657 3.5E-12 T 29-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 THSYN_RS03375 30d62e9f32fcbdb023929921658bf37f 748 Gene3D G3DSA:3.40.1090.10 24 383 5.2E-48 T 29-03-2018 THSYN_RS03375 30d62e9f32fcbdb023929921658bf37f 748 Pfam PF01734 Patatin-like phospholipase 40 231 4.2E-29 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 THSYN_RS03375 30d62e9f32fcbdb023929921658bf37f 748 SUPERFAMILY SSF52151 137 306 9.42E-55 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS03375 30d62e9f32fcbdb023929921658bf37f 748 SUPERFAMILY SSF52151 35 107 9.42E-55 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS03375 30d62e9f32fcbdb023929921658bf37f 748 Gene3D G3DSA:2.40.160.50 384 746 8.6E-21 T 29-03-2018 THSYN_RS02025 7a987545b8f55fefd50b45d78fbc10bd 135 Pfam PF03610 PTS system fructose IIA component 4 106 6.5E-16 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 THSYN_RS02025 7a987545b8f55fefd50b45d78fbc10bd 135 SUPERFAMILY SSF53062 3 128 1.31E-26 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 THSYN_RS02025 7a987545b8f55fefd50b45d78fbc10bd 135 Gene3D G3DSA:3.40.50.510 3 131 3.9E-28 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 THSYN_RS01555 139c6f88bc0c707eb96c58b33ddaaebe 528 SMART SM00382 24 395 4.7E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS01555 139c6f88bc0c707eb96c58b33ddaaebe 528 SUPERFAMILY SSF52540 2 132 1.49E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS01555 139c6f88bc0c707eb96c58b33ddaaebe 528 SUPERFAMILY SSF52540 290 396 1.49E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS01555 139c6f88bc0c707eb96c58b33ddaaebe 528 Gene3D G3DSA:3.40.50.300 1 401 5.1E-24 T 29-03-2018 THSYN_RS01555 139c6f88bc0c707eb96c58b33ddaaebe 528 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 217 381 8.4E-20 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS24670 721e4fa23dc56985fbe0f55dec570379 223 TIGRFAM TIGR04174 IPTL_CTERM: IPTL-CTERM protein sorting domain 194 220 2.7E-7 T 29-03-2018 IPR026442 IPTL-CTERM protein sorting domain THSYN_RS01600 2f78aad4a424af35c2f715a8ad3b1ca2 246 SUPERFAMILY SSF55120 2 236 1.1E-56 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS01600 2f78aad4a424af35c2f715a8ad3b1ca2 246 Gene3D G3DSA:3.30.2350.10 1 236 5.6E-56 T 29-03-2018 THSYN_RS01600 2f78aad4a424af35c2f715a8ad3b1ca2 246 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 49 63 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS01600 2f78aad4a424af35c2f715a8ad3b1ca2 246 Pfam PF00849 RNA pseudouridylate synthase 10 169 3.8E-33 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS06925 a88e48c472fc8469305bb6efa0f56f8b 249 Pfam PF00005 ABC transporter 17 172 3.9E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS06925 a88e48c472fc8469305bb6efa0f56f8b 249 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 244 1.5E-106 T 29-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 THSYN_RS06925 a88e48c472fc8469305bb6efa0f56f8b 249 Gene3D G3DSA:3.40.50.300 1 248 2.9E-40 T 29-03-2018 THSYN_RS06925 a88e48c472fc8469305bb6efa0f56f8b 249 SMART SM00382 26 223 2.6E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS06925 a88e48c472fc8469305bb6efa0f56f8b 249 SUPERFAMILY SSF52540 2 231 1.38E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12885 f005ddfc06899f0d0f5dc08068aec016 696 Gene3D G3DSA:1.20.1250.20 6 211 3.7E-7 T 29-03-2018 THSYN_RS12885 f005ddfc06899f0d0f5dc08068aec016 696 Gene3D G3DSA:3.40.50.150 441 678 4.0E-19 T 29-03-2018 THSYN_RS12885 f005ddfc06899f0d0f5dc08068aec016 696 SUPERFAMILY SSF103473 14 390 1.57E-6 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS12885 f005ddfc06899f0d0f5dc08068aec016 696 SUPERFAMILY SSF53335 501 624 5.05E-20 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS26280 63e58ae6bdfd0f832862160930957bcc 189 Pfam PF03843 Outer membrane lipoprotein Slp family 36 147 2.8E-27 T 29-03-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 Gene3D G3DSA:3.30.70.270 329 496 2.1E-59 T 29-03-2018 THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 323 486 1.6E-44 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 SUPERFAMILY SSF55073 332 490 1.09E-50 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 Gene3D G3DSA:3.20.20.450 497 758 2.7E-102 T 29-03-2018 IPR001633 EAL domain THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 Gene3D G3DSA:3.30.450.20 188 328 1.8E-25 T 29-03-2018 THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 SMART SM00052 498 744 3.2E-117 T 29-03-2018 IPR001633 EAL domain THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 Pfam PF00563 EAL domain 505 739 5.7E-73 T 29-03-2018 IPR001633 EAL domain THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 SMART SM00267 316 488 1.1E-63 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 Pfam PF13426 PAS domain 213 313 1.2E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 Pfam PF00990 Diguanylate cyclase, GGDEF domain 327 483 6.1E-51 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 SMART SM00091 202 268 8.6E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 SUPERFAMILY SSF141868 505 752 4.71E-89 T 29-03-2018 IPR001633 EAL domain THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 207 323 2.2E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 SUPERFAMILY SSF55785 207 313 1.93E-27 T 29-03-2018 IPR000014 PAS domain THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 PIRSF PIRSF005925 315 763 3.9E-147 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 PIRSF PIRSF005925 191 321 9.7E-8 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 Pfam PF07694 5TMR of 5TMR-LYT 39 189 8.6E-11 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 THSYN_RS17540 f1935ea475f6b3ffc3bddae551bc4645 766 SMART SM00086 274 316 0.0017 T 29-03-2018 IPR001610 PAC motif THSYN_RS15045 5788c41aad4859cba29686ff2ede8a25 340 Gene3D G3DSA:3.40.50.300 31 207 6.3E-29 T 29-03-2018 THSYN_RS15045 5788c41aad4859cba29686ff2ede8a25 340 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 50 190 7.3E-58 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 THSYN_RS15045 5788c41aad4859cba29686ff2ede8a25 340 SUPERFAMILY SSF52540 23 311 9.13E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15045 5788c41aad4859cba29686ff2ede8a25 340 Gene3D G3DSA:1.10.8.300 221 335 2.2E-23 T 29-03-2018 THSYN_RS15045 5788c41aad4859cba29686ff2ede8a25 340 SMART SM00382 47 198 7.1E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS15045 5788c41aad4859cba29686ff2ede8a25 340 PIRSF PIRSF002849 2 338 1.4E-111 T 29-03-2018 THSYN_RS17060 1b51db922050ec1327b480d20e2062b7 542 Gene3D G3DSA:3.30.1890.10 77 258 3.3E-13 T 29-03-2018 THSYN_RS17060 1b51db922050ec1327b480d20e2062b7 542 Gene3D G3DSA:1.20.5.50 352 447 0.14 T 29-03-2018 THSYN_RS17060 1b51db922050ec1327b480d20e2062b7 542 Gene3D G3DSA:1.20.5.730 259 337 0.003 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Gene3D G3DSA:2.60.120.640 1137 1238 1.3E-11 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Pfam PF08811 Protein of unknown function (DUF1800) 1235 1738 1.4E-87 T 29-03-2018 IPR014917 Protein of unknown function DUF1800 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SMART SM00758 809 943 9.0E-22 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SMART SM00758 498 632 6.6E-28 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SMART SM00758 654 787 0.012 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SMART SM00758 342 476 6.0E-15 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SMART SM00758 30 164 3.1E-15 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SMART SM00758 965 1099 1.5E-14 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SMART SM00758 186 320 1.1E-16 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SUPERFAMILY SSF56988 694 764 3.4E-7 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SUPERFAMILY SSF56988 540 616 7.98E-12 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SUPERFAMILY SSF56988 381 479 1.57E-14 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SUPERFAMILY SSF56988 69 142 2.35E-12 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Pfam PF07691 PA14 domain 535 631 8.4E-20 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Pfam PF07691 PA14 domain 847 938 8.2E-16 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Pfam PF07691 PA14 domain 379 453 7.4E-13 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Pfam PF07691 PA14 domain 68 158 1.7E-12 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Pfam PF07691 PA14 domain 683 766 7.4E-6 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Pfam PF07691 PA14 domain 225 319 1.0E-15 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Pfam PF07691 PA14 domain 1005 1090 1.8E-13 T 29-03-2018 IPR011658 PA14 domain THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Gene3D G3DSA:2.60.120.380 962 1087 3.1E-23 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SUPERFAMILY SSF56988 226 323 1.44E-12 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SUPERFAMILY SSF56988 850 948 7.72E-14 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Gene3D G3DSA:3.90.182.10 22 180 7.9E-23 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Gene3D G3DSA:3.90.182.10 805 961 3.9E-26 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Gene3D G3DSA:3.90.182.10 491 650 2.1E-24 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Gene3D G3DSA:3.90.182.10 181 333 4.5E-24 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Gene3D G3DSA:3.90.182.10 651 804 9.5E-18 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 Gene3D G3DSA:3.90.182.10 334 490 1.9E-23 T 29-03-2018 THSYN_RS14810 8835164ad5b1b1c632cbb017c03dc59b 1741 SUPERFAMILY SSF56988 1005 1076 7.98E-12 T 29-03-2018 THSYN_RS32015 f4d1b6b63a6fad61fbee9bf6c4f9e8ab 333 Pfam PF02655 ATP-grasp domain 122 288 1.8E-33 T 29-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 THSYN_RS32015 f4d1b6b63a6fad61fbee9bf6c4f9e8ab 333 Gene3D G3DSA:3.30.470.20 115 325 1.8E-25 T 29-03-2018 THSYN_RS32015 f4d1b6b63a6fad61fbee9bf6c4f9e8ab 333 SUPERFAMILY SSF56059 119 313 2.98E-22 T 29-03-2018 THSYN_RS32015 f4d1b6b63a6fad61fbee9bf6c4f9e8ab 333 PIRSF PIRSF016766 1 319 2.3E-73 T 29-03-2018 IPR024710 Tyramine--L-glutamate ligase KEGG: 00680+6.3.4.24|MetaCyc: PWY-5254 THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 155 292 5.0E-52 T 29-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 Pfam PF00583 Acetyltransferase (GNAT) family 785 874 2.9E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 Pfam PF13380 CoA binding domain 15 138 1.6E-20 T 29-03-2018 IPR003781 CoA-binding GO:0048037 THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 Gene3D G3DSA:3.40.50.261 297 460 1.5E-45 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 Gene3D G3DSA:3.40.50.261 130 296 4.1E-42 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 Gene3D G3DSA:3.40.630.30 727 888 4.1E-24 T 29-03-2018 THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 SUPERFAMILY SSF51735 7 134 3.94E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 Pfam PF13549 ATP-grasp domain 482 703 1.6E-69 T 29-03-2018 THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 SMART SM00881 9 104 7.7E-28 T 29-03-2018 IPR003781 CoA-binding GO:0048037 THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 Gene3D G3DSA:3.30.1490.20 510 571 3.6E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 SUPERFAMILY SSF56059 493 705 2.08E-32 T 29-03-2018 THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 SUPERFAMILY SSF52210 300 455 4.06E-44 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 SUPERFAMILY SSF55729 733 883 3.6E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 Gene3D G3DSA:3.40.50.720 5 129 8.9E-35 T 29-03-2018 THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 Gene3D G3DSA:3.30.470.20 572 707 6.8E-29 T 29-03-2018 THSYN_RS27135 a5693db2b7d858a37fe9b7e46f272214 892 SUPERFAMILY SSF52210 133 293 1.57E-41 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THSYN_RS26285 2c0d432813a1a687b79c6a31b86420ca 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 THSYN_RS26285 2c0d432813a1a687b79c6a31b86420ca 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 26.812 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS26285 2c0d432813a1a687b79c6a31b86420ca 95 PRINTS PR00297 10kDa chaperonin signature 3 18 4.4E-32 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS26285 2c0d432813a1a687b79c6a31b86420ca 95 PRINTS PR00297 10kDa chaperonin signature 60 72 4.4E-32 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS26285 2c0d432813a1a687b79c6a31b86420ca 95 PRINTS PR00297 10kDa chaperonin signature 25 46 4.4E-32 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS26285 2c0d432813a1a687b79c6a31b86420ca 95 PRINTS PR00297 10kDa chaperonin signature 81 94 4.4E-32 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS26285 2c0d432813a1a687b79c6a31b86420ca 95 SMART SM00883 2 94 1.5E-56 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS26285 2c0d432813a1a687b79c6a31b86420ca 95 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 7.8E-34 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS26285 2c0d432813a1a687b79c6a31b86420ca 95 Gene3D G3DSA:2.30.33.40 1 95 3.7E-38 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS26285 2c0d432813a1a687b79c6a31b86420ca 95 SUPERFAMILY SSF50129 1 95 5.57E-35 T 29-03-2018 IPR011032 GroES-like THSYN_RS09375 13b02e8b648c27946d48793e414611c5 831 Pfam PF02687 FtsX-like permease family 289 379 1.1E-5 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THSYN_RS33220 0cd6149b8084dd1ea2a29b7ccc4b1ec8 594 Pfam PF09369 Domain of unknown function (DUF1998) 464 561 7.2E-9 T 29-03-2018 IPR018973 DEAD/DEAH-box helicase, putative THSYN_RS11995 84492cc6ed1e1eb7d1300bdc1ccd8881 145 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 22 91 7.1E-7 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS11995 84492cc6ed1e1eb7d1300bdc1ccd8881 145 Gene3D G3DSA:2.30.30.110 12 137 4.3E-7 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 PIRSF PIRSF000171 335 533 6.6E-15 T 29-03-2018 THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 PIRSF PIRSF000171 1 320 3.2E-16 T 29-03-2018 THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 7 519 2.4E-197 T 29-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 Gene3D G3DSA:1.20.58.100 424 535 3.0E-28 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 Pfam PF02910 Fumarate reductase flavoprotein C-term 440 522 2.9E-14 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 Pfam PF00890 FAD binding domain 9 391 4.8E-96 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 Gene3D G3DSA:3.90.700.10 259 347 1.3E-35 T 29-03-2018 THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 SUPERFAMILY SSF46977 424 526 1.31E-30 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 SUPERFAMILY SSF56425 237 352 2.09E-42 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 SUPERFAMILY SSF51905 5 254 2.96E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 SUPERFAMILY SSF51905 355 447 2.96E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 Gene3D G3DSA:3.50.50.60 1 258 2.9E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 4.9E-8 T 29-03-2018 THSYN_RS08360 cf226c5836837997ca6f268d1d47f93c 552 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 354 376 4.9E-8 T 29-03-2018 THSYN_RS17425 261677d3b2ebeb36245f594cc6b09571 205 Pfam PF03734 L,D-transpeptidase catalytic domain 4 159 2.7E-20 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 THSYN_RS17425 261677d3b2ebeb36245f594cc6b09571 205 SUPERFAMILY SSF141523 87 160 4.71E-26 T 29-03-2018 THSYN_RS17425 261677d3b2ebeb36245f594cc6b09571 205 SUPERFAMILY SSF141523 4 59 4.71E-26 T 29-03-2018 THSYN_RS17425 261677d3b2ebeb36245f594cc6b09571 205 Gene3D G3DSA:2.40.440.10 2 161 8.8E-27 T 29-03-2018 THSYN_RS28070 edd6be9e3efedc8a57369b072cbac984 463 TIGRFAM TIGR00260 thrC: threonine synthase 67 422 1.9E-85 T 29-03-2018 IPR004450 Threonine synthase-like THSYN_RS28070 edd6be9e3efedc8a57369b072cbac984 463 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 100 397 2.2E-13 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THSYN_RS28070 edd6be9e3efedc8a57369b072cbac984 463 Pfam PF14821 Threonine synthase N terminus 2 80 4.6E-26 T 29-03-2018 IPR029144 Threonine synthase, N-terminal THSYN_RS28070 edd6be9e3efedc8a57369b072cbac984 463 Gene3D G3DSA:3.40.50.1100 92 205 1.6E-14 T 29-03-2018 THSYN_RS28070 edd6be9e3efedc8a57369b072cbac984 463 Gene3D G3DSA:3.40.50.1100 206 426 1.2E-83 T 29-03-2018 THSYN_RS28070 edd6be9e3efedc8a57369b072cbac984 463 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 101 115 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 THSYN_RS28070 edd6be9e3efedc8a57369b072cbac984 463 Gene3D G3DSA:3.90.1380.10 1 88 1.1E-26 T 29-03-2018 IPR029144 Threonine synthase, N-terminal THSYN_RS28070 edd6be9e3efedc8a57369b072cbac984 463 SUPERFAMILY SSF53686 1 457 1.6E-153 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THSYN_RS00440 cdd2c8aefa8250f6d1b040349d9036de 481 SUPERFAMILY SSF52540 93 363 5.15E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00440 cdd2c8aefa8250f6d1b040349d9036de 481 SUPERFAMILY SSF47917 363 476 2.88E-41 T 29-03-2018 THSYN_RS00440 cdd2c8aefa8250f6d1b040349d9036de 481 Gene3D G3DSA:1.10.1140.10 364 475 3.1E-32 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS00440 cdd2c8aefa8250f6d1b040349d9036de 481 Gene3D G3DSA:3.40.50.300 79 359 2.4E-79 T 29-03-2018 THSYN_RS00440 cdd2c8aefa8250f6d1b040349d9036de 481 SMART SM00382 158 343 2.7E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS00440 cdd2c8aefa8250f6d1b040349d9036de 481 Hamap MF_01347 ATP synthase subunit beta [atpB]. 19 477 47.997 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 THSYN_RS00440 cdd2c8aefa8250f6d1b040349d9036de 481 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 146 359 3.2E-63 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS00440 cdd2c8aefa8250f6d1b040349d9036de 481 Gene3D G3DSA:2.40.10.170 13 78 1.9E-20 T 29-03-2018 THSYN_RS00440 cdd2c8aefa8250f6d1b040349d9036de 481 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 24 89 6.5E-9 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS00440 cdd2c8aefa8250f6d1b040349d9036de 481 SUPERFAMILY SSF50615 16 91 6.8E-19 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS00440 cdd2c8aefa8250f6d1b040349d9036de 481 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 21 475 3.9E-182 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 THSYN_RS00440 cdd2c8aefa8250f6d1b040349d9036de 481 TIGRFAM TIGR03305 alt_F1F0_F1_bet: alternate F1F0 ATPase, F1 subunit beta 22 470 8.6E-265 T 29-03-2018 IPR017691 ATP synthase subunit beta, bacterial and archaeal GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS00440 cdd2c8aefa8250f6d1b040349d9036de 481 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 350 359 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS28285 8066badd648f1865506a6927521a6b66 531 Pfam PF01636 Phosphotransferase enzyme family 99 282 1.9E-10 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase THSYN_RS28285 8066badd648f1865506a6927521a6b66 531 SUPERFAMILY SSF56112 10 330 6.8E-27 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS28285 8066badd648f1865506a6927521a6b66 531 Pfam PF13671 AAA domain 343 495 9.0E-28 T 29-03-2018 THSYN_RS28285 8066badd648f1865506a6927521a6b66 531 Gene3D G3DSA:3.40.50.300 338 525 2.0E-19 T 29-03-2018 THSYN_RS28285 8066badd648f1865506a6927521a6b66 531 SUPERFAMILY SSF52540 336 376 2.47E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS28285 8066badd648f1865506a6927521a6b66 531 SUPERFAMILY SSF52540 407 505 2.47E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS28285 8066badd648f1865506a6927521a6b66 531 Gene3D G3DSA:3.90.1200.10 111 337 2.4E-14 T 29-03-2018 THSYN_RS04430 cff22d8c5bb575592a9412a5bc1e677f 291 Gene3D G3DSA:1.10.10.60 230 284 8.2E-9 T 29-03-2018 THSYN_RS04430 cff22d8c5bb575592a9412a5bc1e677f 291 Pfam PF12784 PD-(D/E)XK nuclease family transposase 7 232 2.0E-35 T 29-03-2018 THSYN_RS04430 cff22d8c5bb575592a9412a5bc1e677f 291 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 8 284 1.1E-39 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA THSYN_RS22400 4017cbbaec477a460ea2146fecedb36f 97 SUPERFAMILY SSF46565 2 55 4.58E-8 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS22400 4017cbbaec477a460ea2146fecedb36f 97 SMART SM00271 2 54 0.0058 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS22400 4017cbbaec477a460ea2146fecedb36f 97 Gene3D G3DSA:1.10.287.110 1 67 2.5E-9 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS19800 6100731d1090a185f892def56f3a926e 118 SMART SM00073 23 118 0.0019 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS19800 6100731d1090a185f892def56f3a926e 118 Pfam PF01627 Hpt domain 33 111 2.5E-9 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS19800 6100731d1090a185f892def56f3a926e 118 Gene3D G3DSA:1.20.120.160 3 117 3.5E-15 T 29-03-2018 THSYN_RS19800 6100731d1090a185f892def56f3a926e 118 SUPERFAMILY SSF47226 9 109 5.23E-18 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS10805 5f82cec634313f9849abdabc316183c1 260 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 THSYN_RS10805 5f82cec634313f9849abdabc316183c1 260 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 19 179 5.1E-71 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 THSYN_RS10805 5f82cec634313f9849abdabc316183c1 260 Gene3D G3DSA:2.160.10.10 75 199 3.6E-36 T 29-03-2018 THSYN_RS10805 5f82cec634313f9849abdabc316183c1 260 Gene3D G3DSA:1.10.3130.10 5 74 7.1E-24 T 29-03-2018 THSYN_RS10805 5f82cec634313f9849abdabc316183c1 260 SUPERFAMILY SSF51161 16 186 6.1E-54 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS10805 5f82cec634313f9849abdabc316183c1 260 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 130 165 1.5E-8 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS10805 5f82cec634313f9849abdabc316183c1 260 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 121 0.0013 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS09595 d1986f1fccfe7602ea3cda006719846c 82 Gene3D G3DSA:1.20.5.340 2 78 4.7E-4 T 29-03-2018 THSYN_RS09595 d1986f1fccfe7602ea3cda006719846c 82 SUPERFAMILY SSF57997 16 81 6.87E-5 T 29-03-2018 THSYN_RS15575 fa1e1e2c3bb1491ee6101efb679d27af 417 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 311 320 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site THSYN_RS15575 fa1e1e2c3bb1491ee6101efb679d27af 417 Pfam PF00158 Sigma-54 interaction domain 98 264 5.9E-57 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THSYN_RS15575 fa1e1e2c3bb1491ee6101efb679d27af 417 Pfam PF02954 Bacterial regulatory protein, Fis family 369 409 2.0E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS15575 fa1e1e2c3bb1491ee6101efb679d27af 417 SUPERFAMILY SSF46689 311 411 1.12E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS15575 fa1e1e2c3bb1491ee6101efb679d27af 417 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 184 199 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THSYN_RS15575 fa1e1e2c3bb1491ee6101efb679d27af 417 Gene3D G3DSA:3.40.50.300 93 270 1.7E-25 T 29-03-2018 THSYN_RS15575 fa1e1e2c3bb1491ee6101efb679d27af 417 SUPERFAMILY SSF52540 97 332 1.59E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15575 fa1e1e2c3bb1491ee6101efb679d27af 417 Gene3D G3DSA:1.10.10.60 346 412 3.0E-8 T 29-03-2018 THSYN_RS15575 fa1e1e2c3bb1491ee6101efb679d27af 417 Gene3D G3DSA:1.10.8.60 271 337 1.0E-19 T 29-03-2018 THSYN_RS15575 fa1e1e2c3bb1491ee6101efb679d27af 417 SMART SM00382 118 262 5.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS02515 4d4e1065005ccd8219a51ec81822fe98 240 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 16 36 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS02515 4d4e1065005ccd8219a51ec81822fe98 240 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 16 37 1.5E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS02515 4d4e1065005ccd8219a51ec81822fe98 240 Pfam PF07963 Prokaryotic N-terminal methylation motif 13 38 5.1E-6 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS12850 8a95ec422fbcf5e94e210a4e6a117a10 195 Pfam PF00072 Response regulator receiver domain 11 119 1.9E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS12850 8a95ec422fbcf5e94e210a4e6a117a10 195 SMART SM00448 9 122 8.5E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS12850 8a95ec422fbcf5e94e210a4e6a117a10 195 Gene3D G3DSA:3.40.50.2300 6 189 4.2E-36 T 29-03-2018 THSYN_RS12850 8a95ec422fbcf5e94e210a4e6a117a10 195 SUPERFAMILY SSF52172 8 134 4.98E-34 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS22265 82f05c72ad96fd303cf647ca7aa2ac65 429 SUPERFAMILY SSF52540 28 94 4.05E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22265 82f05c72ad96fd303cf647ca7aa2ac65 429 SUPERFAMILY SSF52540 130 251 4.05E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22265 82f05c72ad96fd303cf647ca7aa2ac65 429 Gene3D G3DSA:3.40.50.300 39 406 3.0E-4 T 29-03-2018 THSYN_RS14960 a0f2291dc4d3dfa3aba9a8866bd34d15 746 Pfam PF07027 Protein of unknown function (DUF1318) 54 117 3.6E-5 T 29-03-2018 IPR008309 Uncharacterised conserved protein UCP025560 THSYN_RS14960 a0f2291dc4d3dfa3aba9a8866bd34d15 746 SMART SM00327 337 524 6.7E-4 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS14960 a0f2291dc4d3dfa3aba9a8866bd34d15 746 Gene3D G3DSA:3.40.50.410 336 521 7.5E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS14960 a0f2291dc4d3dfa3aba9a8866bd34d15 746 Pfam PF00092 von Willebrand factor type A domain 339 505 8.4E-6 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS14960 a0f2291dc4d3dfa3aba9a8866bd34d15 746 SUPERFAMILY SSF53300 337 510 9.24E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS07840 736f7e92640d908c65246d8dc46ea109 64 Pfam PF10047 Protein of unknown function (DUF2281) 8 52 4.4E-8 T 29-03-2018 IPR018739 Domain of unknown function DUF2281 THSYN_RS15195 7041fee31621e8588fbb5a10b3eb0551 282 Gene3D G3DSA:3.30.450.20 158 272 1.1E-11 T 29-03-2018 THSYN_RS15195 7041fee31621e8588fbb5a10b3eb0551 282 SMART SM00448 11 123 1.8E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS15195 7041fee31621e8588fbb5a10b3eb0551 282 Gene3D G3DSA:3.40.50.2300 5 157 8.3E-33 T 29-03-2018 THSYN_RS15195 7041fee31621e8588fbb5a10b3eb0551 282 SUPERFAMILY SSF55785 149 266 5.02E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS15195 7041fee31621e8588fbb5a10b3eb0551 282 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 155 263 9.8E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS15195 7041fee31621e8588fbb5a10b3eb0551 282 SUPERFAMILY SSF52172 12 165 2.13E-34 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS15195 7041fee31621e8588fbb5a10b3eb0551 282 Pfam PF00072 Response regulator receiver domain 13 123 1.0E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS10320 dddbcf1b1cd568d7ea493805ef160b32 165 Gene3D G3DSA:3.40.920.10 1 100 1.4E-27 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 THSYN_RS10320 dddbcf1b1cd568d7ea493805ef160b32 165 Gene3D G3DSA:3.40.920.10 101 165 2.7E-7 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 THSYN_RS10320 dddbcf1b1cd568d7ea493805ef160b32 165 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 101 5.8E-23 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 THSYN_RS10320 dddbcf1b1cd568d7ea493805ef160b32 165 SUPERFAMILY SSF53323 4 158 6.8E-31 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 THSYN_RS24795 87142e94ea91c65c590eee636da8d18d 252 Gene3D G3DSA:3.90.550.10 1 251 1.6E-48 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS24795 87142e94ea91c65c590eee636da8d18d 252 Pfam PF02348 Cytidylyltransferase 5 223 7.2E-54 T 29-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 THSYN_RS24795 87142e94ea91c65c590eee636da8d18d 252 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 2 243 1.5E-90 T 29-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 THSYN_RS24795 87142e94ea91c65c590eee636da8d18d 252 SUPERFAMILY SSF53448 3 250 3.38E-60 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS24795 87142e94ea91c65c590eee636da8d18d 252 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 251 42.324 T 29-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 THSYN_RS06935 9fb8d2574cdaaecd70368f83205509e2 133 TIGRFAM TIGR02945 SUF_assoc: FeS assembly SUF system protein 36 133 3.4E-46 T 29-03-2018 IPR014291 SUF system FeS cluster assembly associated THSYN_RS06935 9fb8d2574cdaaecd70368f83205509e2 133 Pfam PF01883 Iron-sulfur cluster assembly protein 38 110 3.8E-22 T 29-03-2018 IPR002744 MIP18 family-like THSYN_RS06935 9fb8d2574cdaaecd70368f83205509e2 133 SUPERFAMILY SSF117916 36 132 3.04E-32 T 29-03-2018 IPR034904 Fe-S cluster assembly domain THSYN_RS06935 9fb8d2574cdaaecd70368f83205509e2 133 Gene3D G3DSA:3.30.300.130 33 132 3.4E-28 T 29-03-2018 IPR034904 Fe-S cluster assembly domain THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 401 505 1.3E-15 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 Gene3D G3DSA:3.40.120.10 295 402 2.1E-23 T 29-03-2018 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 SUPERFAMILY SSF53738 401 506 7.46E-28 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 153 278 3.7E-31 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 531 589 1.8E-9 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 Gene3D G3DSA:3.30.310.50 511 604 4.4E-15 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 Gene3D G3DSA:3.40.120.10 403 510 2.7E-20 T 29-03-2018 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 SUPERFAMILY SSF53738 296 397 2.63E-21 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 299 393 2.6E-19 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 SUPERFAMILY SSF55957 511 603 1.19E-17 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 375 390 7.3E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 312 331 7.3E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 241 255 7.3E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 SUPERFAMILY SSF53738 153 281 2.94E-33 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS20705 777c092747fe7dd9a3c2c95d5350ea97 604 Gene3D G3DSA:3.40.120.10 149 281 8.6E-33 T 29-03-2018 THSYN_RS00765 d43130c0026f1424ce489751de89888a 128 Gene3D G3DSA:3.40.50.1010 1 124 1.2E-15 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS00765 d43130c0026f1424ce489751de89888a 128 Pfam PF01850 PIN domain 8 118 4.0E-12 T 29-03-2018 IPR002716 PIN domain THSYN_RS00765 d43130c0026f1424ce489751de89888a 128 SUPERFAMILY SSF88723 8 127 1.18E-18 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS14680 3566b37f10832b9028f2076037c1409b 212 Gene3D G3DSA:3.30.70.60 114 212 0.0015 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 THSYN_RS14680 3566b37f10832b9028f2076037c1409b 212 Pfam PF10741 Type II secretion system (T2SS), protein M subtype b 100 209 5.9E-16 T 29-03-2018 IPR034756 Type II secretion system (T2SS), protein M subtype b THSYN_RS01930 3065a00256ca2487b2c6c6e3d861612d 742 Pfam PF07793 Protein of unknown function (DUF1631) 46 740 8.5E-137 T 29-03-2018 IPR012434 Protein of unknown function DUF1631 THSYN_RS26135 1294cd7f31752c907c08d85b64429b52 288 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 52 65 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS26135 1294cd7f31752c907c08d85b64429b52 288 Gene3D G3DSA:3.20.20.20 3 285 3.2E-110 T 29-03-2018 THSYN_RS26135 1294cd7f31752c907c08d85b64429b52 288 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 18 33 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS26135 1294cd7f31752c907c08d85b64429b52 288 SUPERFAMILY SSF51717 6 275 2.09E-104 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS26135 1294cd7f31752c907c08d85b64429b52 288 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 18 272 3.6E-98 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 THSYN_RS26135 1294cd7f31752c907c08d85b64429b52 288 Pfam PF00809 Pterin binding enzyme 19 258 3.2E-84 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS05160 253b0cce130458dc218286cdb6878750 326 Gene3D G3DSA:3.90.1200.10 92 325 3.1E-39 T 29-03-2018 THSYN_RS05160 253b0cce130458dc218286cdb6878750 326 Gene3D G3DSA:3.30.200.20 1 91 4.1E-27 T 29-03-2018 THSYN_RS05160 253b0cce130458dc218286cdb6878750 326 Pfam PF01636 Phosphotransferase enzyme family 24 235 1.1E-27 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase THSYN_RS05160 253b0cce130458dc218286cdb6878750 326 SUPERFAMILY SSF56112 6 306 2.19E-49 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS29400 0ffab205ee7cfd69c2536d12e0dfc5c9 295 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 106 285 1.8E-24 T 29-03-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein THSYN_RS29400 0ffab205ee7cfd69c2536d12e0dfc5c9 295 Gene3D G3DSA:1.10.1200.80 161 279 0.0019 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 THSYN_RS05710 d350fa254b6f2f41729cb840c9a81967 175 Pfam PF00466 Ribosomal protein L10 5 101 1.1E-24 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 THSYN_RS05710 d350fa254b6f2f41729cb840c9a81967 175 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 29-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS05710 d350fa254b6f2f41729cb840c9a81967 175 SUPERFAMILY SSF160369 4 170 3.14E-50 T 29-03-2018 THSYN_RS05710 d350fa254b6f2f41729cb840c9a81967 175 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 25.017 T 29-03-2018 IPR022973 Ribosomal protein L10 THSYN_RS32005 dc1490954afa247b945498c3bf464cb5 465 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 104 451 9.8E-119 T 29-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 THSYN_RS32005 dc1490954afa247b945498c3bf464cb5 465 PRINTS PR00095 Anthranilate synthase component I signature 389 403 1.2E-19 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THSYN_RS32005 dc1490954afa247b945498c3bf464cb5 465 PRINTS PR00095 Anthranilate synthase component I signature 404 418 1.2E-19 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THSYN_RS32005 dc1490954afa247b945498c3bf464cb5 465 PRINTS PR00095 Anthranilate synthase component I signature 295 308 1.2E-19 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THSYN_RS32005 dc1490954afa247b945498c3bf464cb5 465 PRINTS PR00095 Anthranilate synthase component I signature 309 322 1.2E-19 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THSYN_RS32005 dc1490954afa247b945498c3bf464cb5 465 Pfam PF04715 Anthranilate synthase component I, N terminal region 22 148 9.4E-20 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THSYN_RS32005 dc1490954afa247b945498c3bf464cb5 465 Pfam PF00425 chorismate binding enzyme 193 447 7.8E-101 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal THSYN_RS32005 dc1490954afa247b945498c3bf464cb5 465 Gene3D G3DSA:3.60.120.10 10 457 2.2E-159 T 29-03-2018 IPR005801 ADC synthase GO:0009058 THSYN_RS32005 dc1490954afa247b945498c3bf464cb5 465 SUPERFAMILY SSF56322 25 456 1.44E-148 T 29-03-2018 IPR005801 ADC synthase GO:0009058 THSYN_RS20810 a16d0185b740af6f66b68e5136f443a3 301 SUPERFAMILY SSF48179 177 283 2.27E-34 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THSYN_RS20810 a16d0185b740af6f66b68e5136f443a3 301 Pfam PF02153 Prephenate dehydrogenase 17 274 7.4E-70 T 29-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 THSYN_RS20810 a16d0185b740af6f66b68e5136f443a3 301 Gene3D G3DSA:3.40.50.720 2 173 2.2E-35 T 29-03-2018 THSYN_RS20810 a16d0185b740af6f66b68e5136f443a3 301 Gene3D G3DSA:1.10.3660.10 183 292 5.6E-36 T 29-03-2018 THSYN_RS20810 a16d0185b740af6f66b68e5136f443a3 301 SUPERFAMILY SSF51735 4 171 2.21E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS01565 4d125e43861e7d8f4782e3c705a3ecf0 224 SUPERFAMILY SSF116734 3 176 3.6E-25 T 29-03-2018 THSYN_RS01565 4d125e43861e7d8f4782e3c705a3ecf0 224 Gene3D G3DSA:3.90.220.20 1 174 1.4E-22 T 29-03-2018 THSYN_RS01565 4d125e43861e7d8f4782e3c705a3ecf0 224 Pfam PF01420 Type I restriction modification DNA specificity domain 5 170 1.7E-5 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS18955 9cc0a95bb43f9539da48d31ee2ed02d0 442 Gene3D G3DSA:1.10.287.130 210 270 6.5E-12 T 29-03-2018 THSYN_RS18955 9cc0a95bb43f9539da48d31ee2ed02d0 442 SMART SM00388 227 288 6.4E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS18955 9cc0a95bb43f9539da48d31ee2ed02d0 442 Gene3D G3DSA:3.30.565.10 271 435 1.2E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS18955 9cc0a95bb43f9539da48d31ee2ed02d0 442 SUPERFAMILY SSF55874 278 434 1.31E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS18955 9cc0a95bb43f9539da48d31ee2ed02d0 442 SMART SM00387 325 436 2.8E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS18955 9cc0a95bb43f9539da48d31ee2ed02d0 442 SMART SM00304 174 226 2.6E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS18955 9cc0a95bb43f9539da48d31ee2ed02d0 442 Pfam PF00512 His Kinase A (phospho-acceptor) domain 228 284 2.5E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS18955 9cc0a95bb43f9539da48d31ee2ed02d0 442 SUPERFAMILY SSF47384 210 284 1.96E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS18955 9cc0a95bb43f9539da48d31ee2ed02d0 442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 329 434 3.6E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS18955 9cc0a95bb43f9539da48d31ee2ed02d0 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 375 3.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS18955 9cc0a95bb43f9539da48d31ee2ed02d0 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 414 3.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS18955 9cc0a95bb43f9539da48d31ee2ed02d0 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 433 3.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS18955 9cc0a95bb43f9539da48d31ee2ed02d0 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 389 3.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS20840 7bc8eb55b7677e3442c424d63cd79c48 133 SUPERFAMILY SSF53850 19 132 1.3E-10 T 29-03-2018 THSYN_RS20840 7bc8eb55b7677e3442c424d63cd79c48 133 Gene3D G3DSA:3.40.190.10 17 133 4.4E-10 T 29-03-2018 THSYN_RS13585 f6b32f0a4867565fc7008c28d9e481b5 190 Pfam PF04832 SOUL heme-binding protein 7 184 8.7E-45 T 29-03-2018 IPR006917 SOUL haem-binding protein THSYN_RS13585 f6b32f0a4867565fc7008c28d9e481b5 190 SUPERFAMILY SSF55136 4 185 4.19E-51 T 29-03-2018 THSYN_RS13585 f6b32f0a4867565fc7008c28d9e481b5 190 Gene3D G3DSA:3.20.80.10 20 174 4.4E-4 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 SUPERFAMILY SSF51905 1 317 2.75E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 Gene3D G3DSA:3.30.390.30 326 448 1.2E-22 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 Gene3D G3DSA:3.50.50.60 1 103 1.3E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 SUPERFAMILY SSF55424 324 445 2.23E-28 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 Gene3D G3DSA:3.50.50.60 104 244 1.6E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 Gene3D G3DSA:3.50.50.60 246 323 1.8E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 292 9.3E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 6.1E-17 T 29-03-2018 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 6.1E-17 T 29-03-2018 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 6.1E-17 T 29-03-2018 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 6.1E-17 T 29-03-2018 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 328 430 1.1E-15 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 3.4E-21 T 29-03-2018 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 3.4E-21 T 29-03-2018 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 3.4E-21 T 29-03-2018 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 3.4E-21 T 29-03-2018 THSYN_RS09195 2cd41fc7c645a1f8124be602720f1682 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 3.4E-21 T 29-03-2018 THSYN_RS04100 caa70daf32e7adadf41bdc484e8b4701 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 415 4.4E-131 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit THSYN_RS04100 caa70daf32e7adadf41bdc484e8b4701 427 PIRSF PIRSF006066 1 427 1.3E-157 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 THSYN_RS04100 caa70daf32e7adadf41bdc484e8b4701 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 421 4.1E-157 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 THSYN_RS31995 8bd23116aa009c8594eedfa85de86188 99 Pfam PF08681 Protein of unknown function (DUF1778) 11 86 3.9E-23 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 THSYN_RS31995 8bd23116aa009c8594eedfa85de86188 99 SUPERFAMILY SSF47598 8 85 2.67E-17 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS31995 8bd23116aa009c8594eedfa85de86188 99 Gene3D G3DSA:1.20.5.780 8 87 3.2E-22 T 29-03-2018 THSYN_RS18965 c88089d04d01f8331c011319c4db6422 161 SMART SM00100 15 133 8.1E-14 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS18965 c88089d04d01f8331c011319c4db6422 161 SUPERFAMILY SSF51206 8 138 1.83E-25 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like THSYN_RS18965 c88089d04d01f8331c011319c4db6422 161 Pfam PF00027 Cyclic nucleotide-binding domain 34 119 7.5E-17 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS18965 c88089d04d01f8331c011319c4db6422 161 Gene3D G3DSA:2.60.120.10 2 155 1.3E-25 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS26745 c46747c936d79e22704888c32ea257f3 129 SUPERFAMILY SSF81593 10 106 4.71E-12 T 29-03-2018 THSYN_RS26745 c46747c936d79e22704888c32ea257f3 129 Gene3D G3DSA:1.20.120.330 1 129 1.9E-16 T 29-03-2018 THSYN_RS26745 c46747c936d79e22704888c32ea257f3 129 Pfam PF05168 HEPN domain 8 125 5.5E-15 T 29-03-2018 IPR007842 HEPN domain THSYN_RS26745 c46747c936d79e22704888c32ea257f3 129 SMART SM00748 12 122 0.0011 T 29-03-2018 IPR007842 HEPN domain THSYN_RS15725 900b6ec51fe66738a2b1a3fbf257a60c 89 Gene3D G3DSA:3.30.1070.10 1 83 5.4E-27 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 THSYN_RS15725 900b6ec51fe66738a2b1a3fbf257a60c 89 SUPERFAMILY SSF55229 34 83 1.96E-14 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 THSYN_RS15725 900b6ec51fe66738a2b1a3fbf257a60c 89 Pfam PF03776 Septum formation topological specificity factor MinE 15 82 3.6E-24 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 THSYN_RS15725 900b6ec51fe66738a2b1a3fbf257a60c 89 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 83 4.6E-28 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 THSYN_RS15725 900b6ec51fe66738a2b1a3fbf257a60c 89 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 87 18.649 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 THSYN_RS29185 6f0c40e9ee1fea3b82f7c7b7f17915aa 289 SUPERFAMILY SSF81336 102 282 4.58E-40 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29185 6f0c40e9ee1fea3b82f7c7b7f17915aa 289 ProSitePatterns PS00449 ATP synthase a subunit signature. 218 227 - T 29-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29185 6f0c40e9ee1fea3b82f7c7b7f17915aa 289 Gene3D G3DSA:1.20.120.220 101 288 2.2E-45 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29185 6f0c40e9ee1fea3b82f7c7b7f17915aa 289 Hamap MF_01393 ATP synthase subunit a [atpB]. 13 288 14.977 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29185 6f0c40e9ee1fea3b82f7c7b7f17915aa 289 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 45 282 1.3E-44 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29185 6f0c40e9ee1fea3b82f7c7b7f17915aa 289 Pfam PF00119 ATP synthase A chain 52 281 2.4E-54 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS08335 31121be28c83b5c40ca47bde73861699 812 Gene3D G3DSA:3.40.710.10 364 742 3.5E-96 T 29-03-2018 THSYN_RS08335 31121be28c83b5c40ca47bde73861699 812 SUPERFAMILY SSF53955 166 362 3.37E-63 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS08335 31121be28c83b5c40ca47bde73861699 812 Gene3D G3DSA:1.10.3810.10 159 358 1.2E-60 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 THSYN_RS08335 31121be28c83b5c40ca47bde73861699 812 SUPERFAMILY SSF56601 323 345 1.82E-108 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS08335 31121be28c83b5c40ca47bde73861699 812 SUPERFAMILY SSF56601 374 735 1.82E-108 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS08335 31121be28c83b5c40ca47bde73861699 812 Pfam PF00905 Penicillin binding protein transpeptidase domain 437 683 2.3E-22 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THSYN_RS08335 31121be28c83b5c40ca47bde73861699 812 Pfam PF14814 Bifunctional transglycosylase second domain 74 158 1.8E-23 T 29-03-2018 IPR028166 Bifunctional transglycosylase second domain KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THSYN_RS08335 31121be28c83b5c40ca47bde73861699 812 Gene3D G3DSA:3.30.2060.10 73 158 1.5E-23 T 29-03-2018 THSYN_RS08335 31121be28c83b5c40ca47bde73861699 812 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 39 726 5.8E-254 T 29-03-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THSYN_RS08335 31121be28c83b5c40ca47bde73861699 812 PIRSF PIRSF002799 3 735 2.6E-275 T 29-03-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THSYN_RS08335 31121be28c83b5c40ca47bde73861699 812 Pfam PF00912 Transglycosylase 164 341 2.3E-55 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 THSYN_RS18285 c24d1e8c6c2896542511476db98e052b 218 Pfam PF13384 Homeodomain-like domain 9 45 5.9E-6 T 29-03-2018 THSYN_RS18285 c24d1e8c6c2896542511476db98e052b 218 Gene3D G3DSA:1.10.10.10 2 130 1.7E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS03545 0b6b7b51996d87181cdabc0315843ebd 459 SUPERFAMILY SSF53244 311 457 5.68E-45 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THSYN_RS03545 0b6b7b51996d87181cdabc0315843ebd 459 Gene3D G3DSA:3.90.190.20 312 454 1.4E-39 T 29-03-2018 THSYN_RS03545 0b6b7b51996d87181cdabc0315843ebd 459 Pfam PF08245 Mur ligase middle domain 120 292 2.9E-26 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS03545 0b6b7b51996d87181cdabc0315843ebd 459 SUPERFAMILY SSF51984 15 104 4.97E-18 T 29-03-2018 THSYN_RS03545 0b6b7b51996d87181cdabc0315843ebd 459 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 16 455 6.1E-128 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03545 0b6b7b51996d87181cdabc0315843ebd 459 Gene3D G3DSA:3.40.1190.10 105 311 2.7E-62 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS03545 0b6b7b51996d87181cdabc0315843ebd 459 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 14 457 35.026 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03545 0b6b7b51996d87181cdabc0315843ebd 459 SUPERFAMILY SSF53623 106 309 1.31E-54 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS03545 0b6b7b51996d87181cdabc0315843ebd 459 Gene3D G3DSA:3.40.50.720 4 104 9.4E-16 T 29-03-2018 THSYN_RS03545 0b6b7b51996d87181cdabc0315843ebd 459 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 391 2.9E-9 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THSYN_RS08865 8fb4f2f2a2a7b74aba7507d298e9ce37 477 Gene3D G3DSA:3.30.70.20 300 359 0.14 T 29-03-2018 THSYN_RS08865 8fb4f2f2a2a7b74aba7507d298e9ce37 477 SUPERFAMILY SSF54862 107 127 7.53E-25 T 29-03-2018 THSYN_RS08865 8fb4f2f2a2a7b74aba7507d298e9ce37 477 SUPERFAMILY SSF54862 173 331 7.53E-25 T 29-03-2018 THSYN_RS08865 8fb4f2f2a2a7b74aba7507d298e9ce37 477 Gene3D G3DSA:3.30.70.20 218 273 1.8E-6 T 29-03-2018 THSYN_RS08865 8fb4f2f2a2a7b74aba7507d298e9ce37 477 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 41 474 1.2E-143 T 29-03-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 THSYN_RS08865 8fb4f2f2a2a7b74aba7507d298e9ce37 477 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 356 475 2.6E-28 T 29-03-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain THSYN_RS08865 8fb4f2f2a2a7b74aba7507d298e9ce37 477 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 271 282 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS08865 8fb4f2f2a2a7b74aba7507d298e9ce37 477 Gene3D G3DSA:2.60.40.10 360 475 5.1E-25 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08865 8fb4f2f2a2a7b74aba7507d298e9ce37 477 Pfam PF12801 4Fe-4S binding domain 95 135 3.7E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS08865 8fb4f2f2a2a7b74aba7507d298e9ce37 477 Gene3D G3DSA:3.30.70.20 274 299 0.003 T 29-03-2018 THSYN_RS08865 8fb4f2f2a2a7b74aba7507d298e9ce37 477 Pfam PF13746 4Fe-4S dicluster domain 218 323 1.8E-40 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS27235 9e2c0adec21526ba5bacea5301e6a00e 393 SUPERFAMILY SSF81901 285 391 4.19E-8 T 29-03-2018 THSYN_RS27235 9e2c0adec21526ba5bacea5301e6a00e 393 Gene3D G3DSA:1.25.40.10 198 393 2.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS11640 26aae4c599bd377437cd561528049af1 267 Gene3D G3DSA:3.80.30.10 75 253 3.4E-37 T 29-03-2018 THSYN_RS11640 26aae4c599bd377437cd561528049af1 267 Pfam PF04055 Radical SAM superfamily 31 183 9.7E-21 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS11640 26aae4c599bd377437cd561528049af1 267 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 13 245 2.5E-91 T 29-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 THSYN_RS11640 26aae4c599bd377437cd561528049af1 267 SUPERFAMILY SSF102114 30 223 1.14E-25 T 29-03-2018 THSYN_RS11640 26aae4c599bd377437cd561528049af1 267 Pfam PF13353 4Fe-4S single cluster domain 23 116 6.5E-16 T 29-03-2018 THSYN_RS11640 26aae4c599bd377437cd561528049af1 267 ProSitePatterns PS01087 Radical activating enzymes signature. 25 46 - T 29-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 THSYN_RS06165 c1bd91e3a57b65f277a71fa6e53767eb 392 Gene3D G3DSA:3.90.1150.10 2 164 8.1E-49 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS06165 c1bd91e3a57b65f277a71fa6e53767eb 392 Pfam PF00202 Aminotransferase class-III 11 384 3.4E-112 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THSYN_RS06165 c1bd91e3a57b65f277a71fa6e53767eb 392 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 212 249 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THSYN_RS06165 c1bd91e3a57b65f277a71fa6e53767eb 392 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 2 386 44.668 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 THSYN_RS06165 c1bd91e3a57b65f277a71fa6e53767eb 392 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 5 385 4.4E-144 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 THSYN_RS06165 c1bd91e3a57b65f277a71fa6e53767eb 392 SUPERFAMILY SSF53383 6 385 4.26E-125 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS06165 c1bd91e3a57b65f277a71fa6e53767eb 392 Gene3D G3DSA:3.40.640.10 165 280 4.5E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS06165 c1bd91e3a57b65f277a71fa6e53767eb 392 PIRSF PIRSF000521 1 147 1.9E-10 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THSYN_RS06165 c1bd91e3a57b65f277a71fa6e53767eb 392 PIRSF PIRSF000521 162 388 1.6E-38 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THSYN_RS06165 c1bd91e3a57b65f277a71fa6e53767eb 392 Gene3D G3DSA:3.90.1150.10 281 391 3.6E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 Gene3D G3DSA:3.40.50.300 1 79 1.9E-8 T 29-03-2018 THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 4.1E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 4.1E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 4.1E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 4.1E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 SUPERFAMILY SSF52540 3 297 1.49E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 8.9E-157 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 8.4E-41 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 PIRSF PIRSF006641 1 363 7.4E-152 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 SUPERFAMILY SSF81271 279 360 1.2E-35 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 Pfam PF01926 50S ribosome-binding GTPase 5 121 1.1E-22 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 45.281 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 Gene3D G3DSA:1.10.150.300 110 200 9.8E-27 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 THSYN_RS07895 a01df4921d130dda31c88bee03b6d266 363 Gene3D G3DSA:3.10.20.30 263 362 9.0E-47 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS23325 f1ed84b4fd92e811b056c15441b96f41 465 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 18 364 9.7E-127 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 THSYN_RS23325 f1ed84b4fd92e811b056c15441b96f41 465 Pfam PF02601 Exonuclease VII, large subunit 133 447 1.1E-89 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 THSYN_RS23325 f1ed84b4fd92e811b056c15441b96f41 465 Pfam PF13742 OB-fold nucleic acid binding domain 17 110 1.7E-30 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 THSYN_RS23325 f1ed84b4fd92e811b056c15441b96f41 465 Gene3D G3DSA:2.40.50.140 17 111 8.2E-5 T 29-03-2018 THSYN_RS23325 f1ed84b4fd92e811b056c15441b96f41 465 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 14 451 28.515 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 THSYN_RS07610 02837cc8f28bcb617effb5cf7bcc32d7 416 Pfam PF13175 AAA ATPase domain 7 51 1.6E-8 T 29-03-2018 THSYN_RS07610 02837cc8f28bcb617effb5cf7bcc32d7 416 PIRSF PIRSF029347 5 106 1.3E-16 T 29-03-2018 IPR014555 RecF-like THSYN_RS07610 02837cc8f28bcb617effb5cf7bcc32d7 416 PIRSF PIRSF029347 172 366 1.1E-17 T 29-03-2018 IPR014555 RecF-like THSYN_RS07610 02837cc8f28bcb617effb5cf7bcc32d7 416 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 258 330 4.0E-17 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS07610 02837cc8f28bcb617effb5cf7bcc32d7 416 Gene3D G3DSA:3.40.50.300 6 152 6.3E-10 T 29-03-2018 THSYN_RS07610 02837cc8f28bcb617effb5cf7bcc32d7 416 Gene3D G3DSA:3.40.50.300 176 367 5.6E-11 T 29-03-2018 THSYN_RS07610 02837cc8f28bcb617effb5cf7bcc32d7 416 SUPERFAMILY SSF52540 173 331 1.7E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07610 02837cc8f28bcb617effb5cf7bcc32d7 416 SUPERFAMILY SSF52540 6 97 1.7E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00040 bebe117a3a2d501e97140728097c4ad8 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 63 78 4.5E-68 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00040 bebe117a3a2d501e97140728097c4ad8 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 164 179 4.5E-68 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00040 bebe117a3a2d501e97140728097c4ad8 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 253 269 4.5E-68 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00040 bebe117a3a2d501e97140728097c4ad8 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 141 161 4.5E-68 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00040 bebe117a3a2d501e97140728097c4ad8 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 84 104 4.5E-68 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00040 bebe117a3a2d501e97140728097c4ad8 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 115 139 4.5E-68 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00040 bebe117a3a2d501e97140728097c4ad8 301 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 11 292 8.7E-147 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00040 bebe117a3a2d501e97140728097c4ad8 301 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 9 293 59.504 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00040 bebe117a3a2d501e97140728097c4ad8 301 Gene3D G3DSA:3.30.930.10 3 216 8.7E-86 T 29-03-2018 THSYN_RS00040 bebe117a3a2d501e97140728097c4ad8 301 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 10 300 1.2E-156 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00040 bebe117a3a2d501e97140728097c4ad8 301 SUPERFAMILY SSF55681 10 293 6.71E-130 T 29-03-2018 THSYN_RS00040 bebe117a3a2d501e97140728097c4ad8 301 Gene3D G3DSA:1.20.58.180 218 294 2.1E-31 T 29-03-2018 THSYN_RS09175 650ff6af65eda089569f84143538b30f 304 SUPERFAMILY SSF48317 60 273 6.02E-46 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS09175 650ff6af65eda089569f84143538b30f 304 ProSitePatterns PS01157 Class A bacterial acid phosphatases signature. 191 198 - T 29-03-2018 IPR018296 Acid phosphatase, class A, bacterial, conserved site GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 THSYN_RS09175 650ff6af65eda089569f84143538b30f 304 PIRSF PIRSF000897 29 292 2.2E-98 T 29-03-2018 IPR011158 Nonspecific acid phosphatase, class A GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 THSYN_RS09175 650ff6af65eda089569f84143538b30f 304 Gene3D G3DSA:1.20.144.10 56 278 1.5E-42 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS09175 650ff6af65eda089569f84143538b30f 304 Pfam PF01569 PAP2 superfamily 156 255 7.9E-17 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS09175 650ff6af65eda089569f84143538b30f 304 PRINTS PR00483 Bacterial acid phosphatase class A signature 253 271 1.5E-44 T 29-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 THSYN_RS09175 650ff6af65eda089569f84143538b30f 304 PRINTS PR00483 Bacterial acid phosphatase class A signature 161 179 1.5E-44 T 29-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 THSYN_RS09175 650ff6af65eda089569f84143538b30f 304 PRINTS PR00483 Bacterial acid phosphatase class A signature 97 116 1.5E-44 T 29-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 THSYN_RS09175 650ff6af65eda089569f84143538b30f 304 PRINTS PR00483 Bacterial acid phosphatase class A signature 187 213 1.5E-44 T 29-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 THSYN_RS09175 650ff6af65eda089569f84143538b30f 304 PRINTS PR00483 Bacterial acid phosphatase class A signature 219 243 1.5E-44 T 29-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 THSYN_RS09175 650ff6af65eda089569f84143538b30f 304 SMART SM00014 142 256 2.4E-21 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS23155 efabb67ab27c217c3d0f73d9bc8831ff 215 Gene3D G3DSA:1.20.58.280 78 156 1.1E-4 T 29-03-2018 THSYN_RS23155 efabb67ab27c217c3d0f73d9bc8831ff 215 Gene3D G3DSA:1.25.40.10 157 214 1.5E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23155 efabb67ab27c217c3d0f73d9bc8831ff 215 Pfam PF14559 Tetratricopeptide repeat 140 204 6.8E-7 T 29-03-2018 THSYN_RS23155 efabb67ab27c217c3d0f73d9bc8831ff 215 SUPERFAMILY SSF48452 96 208 7.11E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 134 1.1E-24 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 Pfam PF00679 Elongation factor G C-terminus 395 476 2.8E-22 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 Gene3D G3DSA:3.40.50.300 2 67 5.5E-11 T 29-03-2018 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 Gene3D G3DSA:3.40.50.300 68 185 3.0E-31 T 29-03-2018 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 Gene3D G3DSA:3.30.70.240 401 490 1.5E-18 T 29-03-2018 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 SUPERFAMILY SSF54980 302 387 3.6E-15 T 29-03-2018 IPR035647 EF-G domain III/V-like THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 SUPERFAMILY SSF54980 398 513 8.63E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 SUPERFAMILY SSF50447 151 299 2.65E-33 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 Pfam PF03144 Elongation factor Tu domain 2 219 289 9.5E-10 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 599 3.5E-278 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 Gene3D G3DSA:3.30.70.870 302 400 8.9E-33 T 29-03-2018 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 Pfam PF00009 Elongation factor Tu GTP binding domain 4 195 1.5E-55 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 Gene3D G3DSA:2.40.50.250 491 573 6.4E-38 T 29-03-2018 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 SUPERFAMILY SSF52540 3 207 1.46E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 PRINTS PR00315 GTP-binding elongation factor signature 123 132 6.6E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 PRINTS PR00315 GTP-binding elongation factor signature 51 59 6.6E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 PRINTS PR00315 GTP-binding elongation factor signature 71 81 6.6E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 PRINTS PR00315 GTP-binding elongation factor signature 87 98 6.6E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 PRINTS PR00315 GTP-binding elongation factor signature 7 20 6.6E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THSYN_RS26865 aad8808d4062b4344b4e9ff32a8f5543 607 Gene3D G3DSA:2.40.30.10 186 300 6.6E-23 T 29-03-2018 THSYN_RS28575 5e8692c5b43839d15b37806c131c3cca 178 Pfam PF01625 Peptide methionine sulfoxide reductase 5 158 4.1E-65 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THSYN_RS28575 5e8692c5b43839d15b37806c131c3cca 178 SUPERFAMILY SSF55068 4 168 4.05E-75 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THSYN_RS28575 5e8692c5b43839d15b37806c131c3cca 178 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 4 157 1.3E-61 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THSYN_RS28575 5e8692c5b43839d15b37806c131c3cca 178 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 3 162 37.268 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THSYN_RS28575 5e8692c5b43839d15b37806c131c3cca 178 Gene3D G3DSA:3.30.1060.10 2 174 8.0E-73 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THSYN_RS19450 438d5a955973f97d3aed4f947b37348c 446 Pfam PF01547 Bacterial extracellular solute-binding protein 106 353 1.6E-24 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 THSYN_RS19450 438d5a955973f97d3aed4f947b37348c 446 Gene3D G3DSA:3.40.190.10 155 445 1.8E-37 T 29-03-2018 THSYN_RS19450 438d5a955973f97d3aed4f947b37348c 446 SUPERFAMILY SSF53850 48 433 1.09E-55 T 29-03-2018 THSYN_RS24470 800f66bf4e9affeb29da3d286ccae9ce 242 Gene3D G3DSA:1.20.1080.10 1 240 1.5E-63 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 THSYN_RS24470 800f66bf4e9affeb29da3d286ccae9ce 242 SUPERFAMILY SSF81338 4 236 2.22E-62 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 THSYN_RS24470 800f66bf4e9affeb29da3d286ccae9ce 242 Pfam PF00230 Major intrinsic protein 4 233 7.6E-48 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 THSYN_RS24470 800f66bf4e9affeb29da3d286ccae9ce 242 PRINTS PR00783 Major intrinsic protein family signature 173 195 6.3E-50 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 THSYN_RS24470 800f66bf4e9affeb29da3d286ccae9ce 242 PRINTS PR00783 Major intrinsic protein family signature 143 161 6.3E-50 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 THSYN_RS24470 800f66bf4e9affeb29da3d286ccae9ce 242 PRINTS PR00783 Major intrinsic protein family signature 216 236 6.3E-50 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 THSYN_RS24470 800f66bf4e9affeb29da3d286ccae9ce 242 PRINTS PR00783 Major intrinsic protein family signature 49 73 6.3E-50 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 THSYN_RS24470 800f66bf4e9affeb29da3d286ccae9ce 242 PRINTS PR00783 Major intrinsic protein family signature 86 105 6.3E-50 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 THSYN_RS24470 800f66bf4e9affeb29da3d286ccae9ce 242 PRINTS PR00783 Major intrinsic protein family signature 5 24 6.3E-50 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 THSYN_RS24470 800f66bf4e9affeb29da3d286ccae9ce 242 ProSitePatterns PS00221 MIP family signature. 67 75 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 THSYN_RS24470 800f66bf4e9affeb29da3d286ccae9ce 242 TIGRFAM TIGR00861 MIP: MIP family channel proteins 9 233 3.8E-55 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 323 330 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 Pfam PF01842 ACT domain 296 358 3.2E-12 T 29-03-2018 IPR002912 ACT domain THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 Pfam PF00800 Prephenate dehydratase 112 286 3.3E-59 T 29-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 261 283 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 Gene3D G3DSA:3.40.190.10 200 274 6.0E-26 T 29-03-2018 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 SUPERFAMILY SSF55021 280 375 4.58E-27 T 29-03-2018 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 SUPERFAMILY SSF48600 10 112 1.33E-17 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 SMART SM00830 15 109 2.8E-27 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 TIGRFAM TIGR01807 CM_P2: chorismate mutase 11 99 7.6E-27 T 29-03-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 Gene3D G3DSA:1.20.59.10 6 117 1.5E-34 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 PIRSF PIRSF001500 5 378 2.7E-131 T 29-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 Pfam PF01817 Chorismate mutase type II 15 107 1.3E-21 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 Gene3D G3DSA:3.40.190.10 118 199 2.4E-31 T 29-03-2018 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 Gene3D G3DSA:3.30.70.260 288 377 6.4E-28 T 29-03-2018 THSYN_RS20820 3a94747dabb76e1466b14a7ac377e106 378 SUPERFAMILY SSF53850 109 293 4.13E-57 T 29-03-2018 THSYN_RS14430 a30280cf4c801301c62bfd8ad0800c37 219 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 10 185 9.1E-27 T 29-03-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 THSYN_RS14430 a30280cf4c801301c62bfd8ad0800c37 219 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 10 190 5.4E-26 T 29-03-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 THSYN_RS01755 366053bd03b97d9efe0b418bab497aef 375 Pfam PF01384 Phosphate transporter family 19 361 1.0E-81 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 SUPERFAMILY SSF53748 3 389 1.65E-142 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 Gene3D G3DSA:3.40.50.1260 176 377 1.3E-76 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 29-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 PRINTS PR00477 Phosphoglycerate kinase family signature 133 155 2.8E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 PRINTS PR00477 Phosphoglycerate kinase family signature 365 382 2.8E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 PRINTS PR00477 Phosphoglycerate kinase family signature 105 120 2.8E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 2.8E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 PRINTS PR00477 Phosphoglycerate kinase family signature 342 353 2.8E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 PRINTS PR00477 Phosphoglycerate kinase family signature 187 206 2.8E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 PRINTS PR00477 Phosphoglycerate kinase family signature 309 334 2.8E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 PRINTS PR00477 Phosphoglycerate kinase family signature 164 186 2.8E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 2.8E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 Pfam PF00162 Phosphoglycerate kinase 7 379 1.3E-139 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 Gene3D G3DSA:3.40.50.1260 3 175 4.9E-59 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 389 38.39 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04880 07f417576377f9a142c0d2bb5440e2d9 393 PIRSF PIRSF000724 1 393 9.5E-134 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS08375 ec0a452a16da27d47929315976a1405c 343 Gene3D G3DSA:2.50.20.10 37 266 2.1E-17 T 29-03-2018 THSYN_RS08375 ec0a452a16da27d47929315976a1405c 343 Pfam PF03888 MucB/RseB N-terminal domain 47 215 1.3E-50 T 29-03-2018 IPR033434 MucB/RseB, N-terminal THSYN_RS08375 ec0a452a16da27d47929315976a1405c 343 PIRSF PIRSF005427 13 339 3.6E-74 T 29-03-2018 IPR005588 MucB/RseB THSYN_RS08375 ec0a452a16da27d47929315976a1405c 343 Pfam PF17188 MucB/RseB C-terminal domain 243 331 1.0E-17 T 29-03-2018 IPR033436 MucB/RseB, C-terminal THSYN_RS02810 d0718298f25d01fee0d661c27987c42c 280 Gene3D G3DSA:3.40.50.150 1 279 4.7E-76 T 29-03-2018 THSYN_RS02810 d0718298f25d01fee0d661c27987c42c 280 SUPERFAMILY SSF53335 9 278 4.11E-85 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02810 d0718298f25d01fee0d661c27987c42c 280 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 277 8.3E-80 T 29-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 THSYN_RS02810 d0718298f25d01fee0d661c27987c42c 280 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 265 39.393 T 29-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 THSYN_RS11495 62e87cac415757f9bd29fdde7cac0915 459 Pfam PF00691 OmpA family 345 441 7.4E-10 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS11495 62e87cac415757f9bd29fdde7cac0915 459 Pfam PF09850 Type VI secretion system protein DotU 71 273 6.5E-71 T 29-03-2018 IPR017732 Type IV / VI secretion system, DotU THSYN_RS11495 62e87cac415757f9bd29fdde7cac0915 459 Gene3D G3DSA:3.30.1330.60 308 458 3.9E-25 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS11495 62e87cac415757f9bd29fdde7cac0915 459 SUPERFAMILY SSF103088 334 447 3.01E-22 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS11495 62e87cac415757f9bd29fdde7cac0915 459 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 70 279 2.7E-71 T 29-03-2018 IPR017732 Type IV / VI secretion system, DotU THSYN_RS04385 8706034bce7eaea09bd3e4bb5554c5e7 153 Pfam PF00583 Acetyltransferase (GNAT) family 30 127 1.9E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS04385 8706034bce7eaea09bd3e4bb5554c5e7 153 SUPERFAMILY SSF55729 7 152 2.06E-33 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS04385 8706034bce7eaea09bd3e4bb5554c5e7 153 Gene3D G3DSA:3.40.630.30 8 153 3.3E-34 T 29-03-2018 THSYN_RS04385 8706034bce7eaea09bd3e4bb5554c5e7 153 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 18 148 4.4E-35 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 THSYN_RS33190 e11bbbd3d849c77a3f110230a9e5a244 515 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 149 320 3.4E-43 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS33190 e11bbbd3d849c77a3f110230a9e5a244 515 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 268 283 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS33190 e11bbbd3d849c77a3f110230a9e5a244 515 SUPERFAMILY SSF142984 344 425 1.44E-20 T 29-03-2018 THSYN_RS33190 e11bbbd3d849c77a3f110230a9e5a244 515 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 432 512 4.5E-33 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS33190 e11bbbd3d849c77a3f110230a9e5a244 515 SUPERFAMILY SSF140490 427 513 1.44E-32 T 29-03-2018 THSYN_RS33190 e11bbbd3d849c77a3f110230a9e5a244 515 SUPERFAMILY SSF142019 101 341 1.24E-82 T 29-03-2018 THSYN_RS33190 e11bbbd3d849c77a3f110230a9e5a244 515 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 443 454 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS33190 e11bbbd3d849c77a3f110230a9e5a244 515 SMART SM00928 430 475 4.0E-23 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS26900 efa2c692c10d7d5206576a2117a74382 178 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 57 167 8.0E-21 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THSYN_RS26900 efa2c692c10d7d5206576a2117a74382 178 TIGRFAM TIGR00494 crcB: protein CrcB 57 171 3.6E-27 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THSYN_RS26900 efa2c692c10d7d5206576a2117a74382 178 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 55 172 18.428 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THSYN_RS33280 e63bbe9d354dd63684040031221a2d54 385 SUPERFAMILY SSF46955 37 87 4.12E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain THSYN_RS33280 e63bbe9d354dd63684040031221a2d54 385 SUPERFAMILY SSF52540 100 341 5.97E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS33280 e63bbe9d354dd63684040031221a2d54 385 Pfam PF13614 AAA domain 103 272 2.5E-35 T 29-03-2018 IPR025669 AAA domain THSYN_RS33280 e63bbe9d354dd63684040031221a2d54 385 Gene3D G3DSA:3.40.50.300 100 376 1.9E-45 T 29-03-2018 THSYN_RS33280 e63bbe9d354dd63684040031221a2d54 385 Gene3D G3DSA:1.10.1660.10 34 97 3.2E-6 T 29-03-2018 THSYN_RS11245 27642dd04bcb592f3717c1864f2373da 1013 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 58 351 2.0E-38 T 29-03-2018 IPR010090 Phage tail tape measure protein THSYN_RS11245 27642dd04bcb592f3717c1864f2373da 1013 Pfam PF10145 Phage-related minor tail protein 90 325 3.1E-31 T 29-03-2018 IPR010090 Phage tail tape measure protein THSYN_RS11245 27642dd04bcb592f3717c1864f2373da 1013 Gene3D G3DSA:1.20.58.60 54 887 0.042 T 29-03-2018 THSYN_RS23745 fb1b822aae1a3cf79bbb86d81ecf6ec9 193 SUPERFAMILY SSF52980 5 161 3.06E-24 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS23745 fb1b822aae1a3cf79bbb86d81ecf6ec9 193 Gene3D G3DSA:3.90.1570.10 2 189 5.4E-43 T 29-03-2018 THSYN_RS23745 fb1b822aae1a3cf79bbb86d81ecf6ec9 193 Pfam PF05685 Putative restriction endonuclease 11 161 2.1E-32 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS25675 246c4e0395fe5e85cbceec03705d5b16 529 Gene3D G3DSA:1.10.101.10 425 487 8.5E-11 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS25675 246c4e0395fe5e85cbceec03705d5b16 529 SUPERFAMILY SSF56436 95 154 6.12E-27 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS25675 246c4e0395fe5e85cbceec03705d5b16 529 SUPERFAMILY SSF56436 185 315 6.12E-27 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS25675 246c4e0395fe5e85cbceec03705d5b16 529 Pfam PF03781 Sulfatase-modifying factor enzyme 1 93 314 2.3E-24 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS25675 246c4e0395fe5e85cbceec03705d5b16 529 Gene3D G3DSA:3.90.1580.10 93 327 5.7E-23 T 29-03-2018 THSYN_RS25675 246c4e0395fe5e85cbceec03705d5b16 529 SUPERFAMILY SSF47090 425 486 3.77E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS25675 246c4e0395fe5e85cbceec03705d5b16 529 Pfam PF01471 Putative peptidoglycan binding domain 430 483 7.6E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS27660 316dd08434f54aabb685fbf6357cc55f 192 Gene3D G3DSA:3.40.50.1470 2 192 1.8E-62 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THSYN_RS27660 316dd08434f54aabb685fbf6357cc55f 192 Pfam PF01195 Peptidyl-tRNA hydrolase 8 188 3.8E-53 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THSYN_RS27660 316dd08434f54aabb685fbf6357cc55f 192 SUPERFAMILY SSF53178 7 189 1.83E-62 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THSYN_RS27660 316dd08434f54aabb685fbf6357cc55f 192 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 19 32 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 THSYN_RS27660 316dd08434f54aabb685fbf6357cc55f 192 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 6 182 33.516 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THSYN_RS27660 316dd08434f54aabb685fbf6357cc55f 192 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 111 121 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 THSYN_RS27660 316dd08434f54aabb685fbf6357cc55f 192 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 7 189 8.5E-60 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THSYN_RS16165 5e7f6054c6a1c7d405066026d7a898f2 345 Gene3D G3DSA:3.40.50.300 21 179 7.6E-28 T 29-03-2018 THSYN_RS16165 5e7f6054c6a1c7d405066026d7a898f2 345 Pfam PF13177 DNA polymerase III, delta subunit 22 179 7.8E-43 T 29-03-2018 THSYN_RS16165 5e7f6054c6a1c7d405066026d7a898f2 345 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 22 212 1.5E-58 T 29-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS16165 5e7f6054c6a1c7d405066026d7a898f2 345 SUPERFAMILY SSF52540 15 213 3.0E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16165 5e7f6054c6a1c7d405066026d7a898f2 345 Gene3D G3DSA:1.20.272.10 219 341 1.3E-12 T 29-03-2018 THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 Gene3D G3DSA:3.30.450.20 935 1096 0.0015 T 29-03-2018 THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 Pfam PF10114 Sensory domain found in PocR 994 1156 1.5E-43 T 29-03-2018 IPR018771 PocR domain THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 SMART SM00086 1254 1296 3.0E-8 T 29-03-2018 IPR001610 PAC motif THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 SUPERFAMILY SSF55785 1166 1294 6.11E-26 T 29-03-2018 IPR000014 PAS domain THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 Gene3D G3DSA:3.30.70.270 1320 1491 1.9E-53 T 29-03-2018 THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 SMART SM00267 1310 1485 7.7E-69 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 Gene3D G3DSA:3.30.450.40 760 934 6.7E-22 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 Gene3D G3DSA:3.30.450.20 1151 1319 1.4E-34 T 29-03-2018 THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 SUPERFAMILY SSF55781 780 929 9.6E-17 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 SMART SM00065 775 928 1.5E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 1176 1303 1.6E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 Pfam PF08447 PAS fold 1205 1286 4.0E-11 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1318 1483 5.6E-52 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1322 1481 5.9E-47 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS05555 93137111ea607c38ab6c59e8ae77efbd 1494 SUPERFAMILY SSF55073 1326 1483 1.57E-44 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS26015 32d05c7ddae216ce21aac06d2301d1a6 422 PIRSF PIRSF029347 2 98 2.2E-6 T 29-03-2018 IPR014555 RecF-like THSYN_RS26015 32d05c7ddae216ce21aac06d2301d1a6 422 PIRSF PIRSF029347 162 396 2.2E-22 T 29-03-2018 IPR014555 RecF-like THSYN_RS26015 32d05c7ddae216ce21aac06d2301d1a6 422 Gene3D G3DSA:3.40.50.300 2 385 1.5E-22 T 29-03-2018 THSYN_RS26015 32d05c7ddae216ce21aac06d2301d1a6 422 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 200 371 7.5E-27 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS26015 32d05c7ddae216ce21aac06d2301d1a6 422 SUPERFAMILY SSF52540 200 388 4.58E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26015 32d05c7ddae216ce21aac06d2301d1a6 422 SUPERFAMILY SSF52540 1 104 4.58E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS33130 7adf5278200b59f450ce7eff1274e37c 327 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 8 254 1.5E-30 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA THSYN_RS33130 7adf5278200b59f450ce7eff1274e37c 327 Pfam PF12784 PD-(D/E)XK nuclease family transposase 7 228 8.6E-47 T 29-03-2018 THSYN_RS00975 6ad9284fe4acc83e5c089ad0991b3aed 219 SUPERFAMILY SSF75445 126 197 3.14E-23 T 29-03-2018 THSYN_RS00975 6ad9284fe4acc83e5c089ad0991b3aed 219 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 216 32.541 T 29-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THSYN_RS00975 6ad9284fe4acc83e5c089ad0991b3aed 219 Gene3D G3DSA:3.30.70.260 137 195 1.1E-22 T 29-03-2018 THSYN_RS00975 6ad9284fe4acc83e5c089ad0991b3aed 219 Gene3D G3DSA:3.40.50.1360 1 136 2.6E-37 T 29-03-2018 THSYN_RS00975 6ad9284fe4acc83e5c089ad0991b3aed 219 SUPERFAMILY SSF100950 1 145 8.9E-41 T 29-03-2018 THSYN_RS00975 6ad9284fe4acc83e5c089ad0991b3aed 219 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 212 9.2E-64 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THSYN_RS00975 6ad9284fe4acc83e5c089ad0991b3aed 219 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 48 212 7.6E-56 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THSYN_RS10420 e808f726c0c642b05e8f78ea9ce707fa 201 Gene3D G3DSA:1.10.287.540 58 93 9.2E-18 T 29-03-2018 THSYN_RS10420 e808f726c0c642b05e8f78ea9ce707fa 201 Pfam PF04350 Pilus assembly protein, PilO 51 196 8.9E-56 T 29-03-2018 IPR007445 Pilus assembly protein, PilO THSYN_RS10420 e808f726c0c642b05e8f78ea9ce707fa 201 Gene3D G3DSA:3.30.70.60 94 201 9.4E-26 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 THSYN_RS10420 e808f726c0c642b05e8f78ea9ce707fa 201 PIRSF PIRSF016482 1 201 9.4E-66 T 29-03-2018 IPR007445 Pilus assembly protein, PilO THSYN_RS28400 899a507ac21cea279fb146079cf2ffa9 324 Pfam PF00174 Oxidoreductase molybdopterin binding domain 103 259 8.4E-29 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 THSYN_RS28400 899a507ac21cea279fb146079cf2ffa9 324 SUPERFAMILY SSF56524 73 320 3.14E-90 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 THSYN_RS28400 899a507ac21cea279fb146079cf2ffa9 324 Gene3D G3DSA:3.90.420.10 52 284 3.5E-57 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 THSYN_RS28400 899a507ac21cea279fb146079cf2ffa9 324 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 7 324 55.82 T 29-03-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 THSYN_RS04155 30bbb7c64bf066c719cd8be38dbbc110 274 Gene3D G3DSA:3.60.21.10 24 250 1.7E-17 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS04155 30bbb7c64bf066c719cd8be38dbbc110 274 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 264 89.467 T 29-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 THSYN_RS04155 30bbb7c64bf066c719cd8be38dbbc110 274 Pfam PF00149 Calcineurin-like phosphoesterase 25 221 5.2E-6 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS04155 30bbb7c64bf066c719cd8be38dbbc110 274 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 25 250 6.1E-78 T 29-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 THSYN_RS04155 30bbb7c64bf066c719cd8be38dbbc110 274 SUPERFAMILY SSF56300 25 226 4.91E-23 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS23085 f4465e5877cc0992498693c87a2a78ab 631 Pfam PF00005 ABC transporter 337 469 6.7E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS23085 f4465e5877cc0992498693c87a2a78ab 631 Pfam PF00005 ABC transporter 19 185 6.4E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS23085 f4465e5877cc0992498693c87a2a78ab 631 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS23085 f4465e5877cc0992498693c87a2a78ab 631 Pfam PF16326 ABC transporter C-terminal domain 560 628 1.3E-21 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 THSYN_RS23085 f4465e5877cc0992498693c87a2a78ab 631 SUPERFAMILY SSF52540 310 517 4.9E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23085 f4465e5877cc0992498693c87a2a78ab 631 Gene3D G3DSA:3.40.50.300 3 85 2.7E-9 T 29-03-2018 THSYN_RS23085 f4465e5877cc0992498693c87a2a78ab 631 Gene3D G3DSA:3.40.50.300 98 291 1.5E-43 T 29-03-2018 THSYN_RS23085 f4465e5877cc0992498693c87a2a78ab 631 SMART SM00382 344 514 9.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS23085 f4465e5877cc0992498693c87a2a78ab 631 SMART SM00382 28 230 2.3E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS23085 f4465e5877cc0992498693c87a2a78ab 631 Pfam PF12848 ABC transporter 224 302 1.2E-10 T 29-03-2018 IPR032781 ABC-transporter extension domain THSYN_RS23085 f4465e5877cc0992498693c87a2a78ab 631 Gene3D G3DSA:3.40.50.300 292 542 1.0E-54 T 29-03-2018 THSYN_RS23085 f4465e5877cc0992498693c87a2a78ab 631 SUPERFAMILY SSF52540 4 231 4.67E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09070 98ae6128be05ca56619260efc3d46b80 76 Pfam PF01722 BolA-like protein 21 74 5.2E-16 T 29-03-2018 IPR002634 BolA protein THSYN_RS09070 98ae6128be05ca56619260efc3d46b80 76 PIRSF PIRSF003113 1 76 1.6E-17 T 29-03-2018 IPR002634 BolA protein THSYN_RS09070 98ae6128be05ca56619260efc3d46b80 76 Gene3D G3DSA:3.30.300.90 1 76 5.9E-22 T 29-03-2018 THSYN_RS09070 98ae6128be05ca56619260efc3d46b80 76 SUPERFAMILY SSF82657 3 74 9.94E-23 T 29-03-2018 IPR002634 BolA protein THSYN_RS11635 b85fb777dfb9ce1d7917470a2d9d9659 772 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 28 768 0.0 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 THSYN_RS11635 b85fb777dfb9ce1d7917470a2d9d9659 772 ProSitePatterns PS00850 Glycine radical domain signature. 741 749 - T 29-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site THSYN_RS11635 b85fb777dfb9ce1d7917470a2d9d9659 772 Pfam PF01228 Glycine radical 641 752 1.2E-40 T 29-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 THSYN_RS11635 b85fb777dfb9ce1d7917470a2d9d9659 772 Pfam PF02901 Pyruvate formate lyase-like 39 625 7.1E-197 T 29-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 THSYN_RS11635 b85fb777dfb9ce1d7917470a2d9d9659 772 Gene3D G3DSA:3.20.70.20 19 770 6.9E-282 T 29-03-2018 THSYN_RS11635 b85fb777dfb9ce1d7917470a2d9d9659 772 SUPERFAMILY SSF51998 24 770 2.01E-275 T 29-03-2018 THSYN_RS11635 b85fb777dfb9ce1d7917470a2d9d9659 772 PIRSF PIRSF000379 24 770 0.0 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Gene3D G3DSA:3.30.1950.10 54 122 9.4E-12 T 29-03-2018 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Gene3D G3DSA:3.10.560.10 402 501 3.9E-12 T 29-03-2018 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Gene3D G3DSA:3.10.560.10 507 603 6.5E-15 T 29-03-2018 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Pfam PF10531 SLBB domain 418 455 9.9E-5 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Pfam PF10531 SLBB domain 233 279 6.1E-7 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Pfam PF10531 SLBB domain 522 571 0.0045 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Pfam PF10531 SLBB domain 127 176 3.3E-7 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Pfam PF10531 SLBB domain 322 373 7.0E-9 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Pfam PF10531 SLBB domain 617 660 2.0E-9 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Pfam PF02563 Polysaccharide biosynthesis/export protein 47 113 3.1E-11 T 29-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Gene3D G3DSA:3.10.560.10 606 699 8.4E-17 T 29-03-2018 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Gene3D G3DSA:3.10.560.10 123 205 1.6E-14 T 29-03-2018 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Gene3D G3DSA:3.10.560.10 311 401 3.9E-16 T 29-03-2018 THSYN_RS17005 81d572964f6769c48e8513cd92469b06 731 Gene3D G3DSA:3.10.560.10 218 310 1.0E-18 T 29-03-2018 THSYN_RS24350 060a40be6262621d260bf68e0aa16dd1 171 Gene3D G3DSA:3.30.1950.10 27 88 1.5E-15 T 29-03-2018 THSYN_RS24350 060a40be6262621d260bf68e0aa16dd1 171 Pfam PF10531 SLBB domain 100 142 1.1E-11 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24350 060a40be6262621d260bf68e0aa16dd1 171 Pfam PF02563 Polysaccharide biosynthesis/export protein 21 93 8.2E-19 T 29-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 THSYN_RS24350 060a40be6262621d260bf68e0aa16dd1 171 Gene3D G3DSA:3.10.560.10 89 168 8.8E-16 T 29-03-2018 THSYN_RS27985 0c1909474a30ab3a4848302f1c1d41ab 262 Pfam PF14341 PilX N-terminal 67 115 4.9E-12 T 29-03-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain THSYN_RS19440 3ae3f42c10fce67ced241bb2fcda60a0 1061 SUPERFAMILY SSF82689 938 1037 1.83E-14 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 THSYN_RS19440 3ae3f42c10fce67ced241bb2fcda60a0 1061 Gene3D G3DSA:3.30.70.100 937 1033 3.3E-12 T 29-03-2018 THSYN_RS19440 3ae3f42c10fce67ced241bb2fcda60a0 1061 Pfam PF00924 Mechanosensitive ion channel 827 1000 5.9E-45 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THSYN_RS19440 3ae3f42c10fce67ced241bb2fcda60a0 1061 SUPERFAMILY SSF50182 869 935 3.6E-15 T 29-03-2018 IPR010920 LSM domain THSYN_RS19440 3ae3f42c10fce67ced241bb2fcda60a0 1061 Gene3D G3DSA:2.30.30.60 886 936 2.4E-12 T 29-03-2018 THSYN_RS19440 3ae3f42c10fce67ced241bb2fcda60a0 1061 SUPERFAMILY SSF82861 786 868 1.96E-13 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 THSYN_RS07135 7fd9460ecb25f983a372e0e2330b5587 223 Gene3D G3DSA:3.40.50.1240 58 211 5.9E-15 T 29-03-2018 IPR029033 Histidine phosphatase superfamily THSYN_RS07135 7fd9460ecb25f983a372e0e2330b5587 223 SUPERFAMILY SSF53254 62 199 2.16E-15 T 29-03-2018 IPR029033 Histidine phosphatase superfamily THSYN_RS07135 7fd9460ecb25f983a372e0e2330b5587 223 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 62 143 4.5E-8 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THSYN_RS21410 ddeffb16d59da5ca7cb6c9e6173d5207 436 SUPERFAMILY SSF102114 136 358 3.14E-47 T 29-03-2018 THSYN_RS21410 ddeffb16d59da5ca7cb6c9e6173d5207 436 Pfam PF00919 Uncharacterized protein family UPF0004 6 96 7.7E-20 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 THSYN_RS21410 ddeffb16d59da5ca7cb6c9e6173d5207 436 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 143 163 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 THSYN_RS21410 ddeffb16d59da5ca7cb6c9e6173d5207 436 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 6 421 8.6E-103 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 THSYN_RS21410 ddeffb16d59da5ca7cb6c9e6173d5207 436 Pfam PF04055 Radical SAM superfamily 144 312 1.2E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS21410 ddeffb16d59da5ca7cb6c9e6173d5207 436 SMART SM00729 139 354 8.8E-42 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS21410 ddeffb16d59da5ca7cb6c9e6173d5207 436 Gene3D G3DSA:3.80.30.20 136 368 9.8E-38 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe THSYN_RS19150 9c05b952738becdb900771b64f19d561 127 Pfam PF01475 Ferric uptake regulator family 5 115 7.1E-21 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 THSYN_RS19150 9c05b952738becdb900771b64f19d561 127 SUPERFAMILY SSF46785 5 119 5.44E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19150 9c05b952738becdb900771b64f19d561 127 Gene3D G3DSA:1.10.10.10 2 78 2.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS30370 58f31fc2f48dfc7a59a8b43560440eb5 129 Gene3D G3DSA:1.10.10.10 7 59 0.0017 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS24655 582c5e9d7bd02a7ea95602089179fdb5 254 SUPERFAMILY SSF51351 1 248 2.36E-91 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS24655 582c5e9d7bd02a7ea95602089179fdb5 254 Gene3D G3DSA:3.20.20.70 1 254 2.4E-98 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS24655 582c5e9d7bd02a7ea95602089179fdb5 254 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 40.443 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS24655 582c5e9d7bd02a7ea95602089179fdb5 254 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS24655 582c5e9d7bd02a7ea95602089179fdb5 254 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 1.8E-67 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS24655 582c5e9d7bd02a7ea95602089179fdb5 254 Pfam PF00121 Triosephosphate isomerase 5 245 3.4E-88 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04305 86a3bdfc8a2f005a6cac9a00979f8550 200 Gene3D G3DSA:3.30.2310.20 126 199 3.4E-12 T 29-03-2018 THSYN_RS04305 86a3bdfc8a2f005a6cac9a00979f8550 200 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 134 199 3.7E-19 T 29-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 THSYN_RS04305 86a3bdfc8a2f005a6cac9a00979f8550 200 SUPERFAMILY SSF143011 139 199 8.04E-15 T 29-03-2018 IPR035095 Toxin RelE-like domain THSYN_RS04305 86a3bdfc8a2f005a6cac9a00979f8550 200 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 138 199 2.2E-23 T 29-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 THSYN_RS27345 e3f40d1b5e89746684fee05ef6fdceec 103 SUPERFAMILY SSF81301 5 102 2.05E-18 T 29-03-2018 THSYN_RS27345 e3f40d1b5e89746684fee05ef6fdceec 103 Pfam PF01909 Nucleotidyltransferase domain 20 70 6.1E-10 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS27345 e3f40d1b5e89746684fee05ef6fdceec 103 Gene3D G3DSA:3.30.460.10 2 101 9.9E-18 T 29-03-2018 THSYN_RS04750 54fdedf2c909f8626f91aa63f6395386 107 PIRSF PIRSF039032 1 106 3.0E-34 T 29-03-2018 IPR009387 Toxin HigB-2 THSYN_RS04750 54fdedf2c909f8626f91aa63f6395386 107 Pfam PF06296 RelE toxin of RelE / RelB toxin-antitoxin system 9 98 1.5E-8 T 29-03-2018 IPR009387 Toxin HigB-2 THSYN_RS31940 ad04b9ea2b25de549f0be2afa6e6da1e 89 Gene3D G3DSA:1.20.5.780 4 85 8.4E-16 T 29-03-2018 THSYN_RS31940 ad04b9ea2b25de549f0be2afa6e6da1e 89 Pfam PF08681 Protein of unknown function (DUF1778) 8 76 2.2E-11 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 THSYN_RS31940 ad04b9ea2b25de549f0be2afa6e6da1e 89 SUPERFAMILY SSF47598 7 80 1.85E-11 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS06250 4587fb884262245327729616a2ae73ed 221 Pfam PF13353 4Fe-4S single cluster domain 15 150 1.2E-26 T 29-03-2018 THSYN_RS06250 4587fb884262245327729616a2ae73ed 221 Gene3D G3DSA:3.20.20.70 10 158 3.8E-10 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS06250 4587fb884262245327729616a2ae73ed 221 SUPERFAMILY SSF102114 6 113 1.57E-7 T 29-03-2018 THSYN_RS20035 e374f58004e4aa864ecc2256388c6e98 453 Gene3D G3DSA:3.30.565.10 290 453 4.3E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS20035 e374f58004e4aa864ecc2256388c6e98 453 SUPERFAMILY SSF55874 312 452 3.14E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS20035 e374f58004e4aa864ecc2256388c6e98 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 452 1.3E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS20035 e374f58004e4aa864ecc2256388c6e98 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 1.0E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS20035 e374f58004e4aa864ecc2256388c6e98 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 398 1.0E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS20035 e374f58004e4aa864ecc2256388c6e98 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 1.0E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS20035 e374f58004e4aa864ecc2256388c6e98 453 SUPERFAMILY SSF47384 221 302 6.87E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS20035 e374f58004e4aa864ecc2256388c6e98 453 SMART SM00387 349 453 1.9E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS20035 e374f58004e4aa864ecc2256388c6e98 453 Gene3D G3DSA:1.10.287.130 225 289 0.0017 T 29-03-2018 THSYN_RS20035 e374f58004e4aa864ecc2256388c6e98 453 SMART SM00388 238 306 7.6E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS08535 62a53201b6f3bdbce57dffe641c20c78 96 SUPERFAMILY SSF53955 1 87 9.56E-11 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS08535 62a53201b6f3bdbce57dffe641c20c78 96 Pfam PF13406 Transglycosylase SLT domain 1 86 1.8E-12 T 29-03-2018 IPR031304 Transglycosylase SLT domain 2 THSYN_RS08535 62a53201b6f3bdbce57dffe641c20c78 96 Gene3D G3DSA:1.10.530.10 1 89 2.7E-14 T 29-03-2018 THSYN_RS17245 837a23c08e43c11490449d4bb2becd31 393 Pfam PF03781 Sulfatase-modifying factor enzyme 1 130 365 5.7E-40 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS17245 837a23c08e43c11490449d4bb2becd31 393 SUPERFAMILY SSF56436 120 202 1.32E-62 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS17245 837a23c08e43c11490449d4bb2becd31 393 SUPERFAMILY SSF56436 230 367 1.32E-62 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS17245 837a23c08e43c11490449d4bb2becd31 393 Gene3D G3DSA:3.90.1580.10 108 169 0.001 T 29-03-2018 THSYN_RS17245 837a23c08e43c11490449d4bb2becd31 393 Gene3D G3DSA:3.90.1580.10 170 380 4.3E-55 T 29-03-2018 THSYN_RS09425 83e397d6a388406d77e27294eaebcd77 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS09425 83e397d6a388406d77e27294eaebcd77 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 4.3E-37 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS09425 83e397d6a388406d77e27294eaebcd77 89 Gene3D G3DSA:1.10.287.10 2 89 2.9E-33 T 29-03-2018 THSYN_RS09425 83e397d6a388406d77e27294eaebcd77 89 Pfam PF00312 Ribosomal protein S15 8 88 2.0E-35 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS09425 83e397d6a388406d77e27294eaebcd77 89 SMART SM01387 8 88 2.1E-48 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS09425 83e397d6a388406d77e27294eaebcd77 89 SUPERFAMILY SSF47060 3 89 1.29E-33 T 29-03-2018 IPR009068 S15/NS1, RNA-binding THSYN_RS09425 83e397d6a388406d77e27294eaebcd77 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 2.0E-28 T 29-03-2018 THSYN_RS09425 83e397d6a388406d77e27294eaebcd77 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.414 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS26035 1576502fefb2957c497fd48967e2c394 224 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 30 217 3.7E-59 T 29-03-2018 THSYN_RS26035 1576502fefb2957c497fd48967e2c394 224 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 1 220 37.674 T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THSYN_RS26035 1576502fefb2957c497fd48967e2c394 224 Gene3D G3DSA:3.40.50.150 2 223 2.0E-39 T 29-03-2018 THSYN_RS26035 1576502fefb2957c497fd48967e2c394 224 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 29 218 4.1E-59 T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THSYN_RS26035 1576502fefb2957c497fd48967e2c394 224 SUPERFAMILY SSF53335 29 218 2.25E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS21620 4e0fc2ac8b353d1b1dae527455a5ae0e 207 Gene3D G3DSA:3.40.10.10 16 92 7.8E-9 T 29-03-2018 IPR035451 Ada-like domain THSYN_RS06915 3deb01d4f81f0c4b2b82bb0d73941b32 155 Gene3D G3DSA:3.30.310.70 22 155 1.3E-12 T 29-03-2018 IPR005180 Domain of unknown function DUF302 THSYN_RS06915 3deb01d4f81f0c4b2b82bb0d73941b32 155 SUPERFAMILY SSF103247 27 152 1.18E-11 T 29-03-2018 IPR005180 Domain of unknown function DUF302 THSYN_RS06840 dad622f1cab772731d09e60a40649f4b 394 Gene3D G3DSA:3.40.47.10 1 160 7.9E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS06840 dad622f1cab772731d09e60a40649f4b 394 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 THSYN_RS06840 dad622f1cab772731d09e60a40649f4b 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 391 4.9E-127 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 THSYN_RS06840 dad622f1cab772731d09e60a40649f4b 394 SUPERFAMILY SSF53901 271 392 4.11E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS06840 dad622f1cab772731d09e60a40649f4b 394 PIRSF PIRSF000429 1 394 1.4E-116 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 THSYN_RS06840 dad622f1cab772731d09e60a40649f4b 394 Gene3D G3DSA:3.40.47.10 267 390 1.1E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS06840 dad622f1cab772731d09e60a40649f4b 394 Gene3D G3DSA:3.40.47.10 161 266 1.6E-25 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS06840 dad622f1cab772731d09e60a40649f4b 394 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 THSYN_RS06840 dad622f1cab772731d09e60a40649f4b 394 SUPERFAMILY SSF53901 4 269 2.05E-74 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS06840 dad622f1cab772731d09e60a40649f4b 394 Pfam PF02803 Thiolase, C-terminal domain 270 392 1.2E-43 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THSYN_RS06840 dad622f1cab772731d09e60a40649f4b 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 THSYN_RS06840 dad622f1cab772731d09e60a40649f4b 394 Pfam PF00108 Thiolase, N-terminal domain 5 262 2.7E-82 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THSYN_RS24825 e8ac17fdb77da060a530d9e2fbb7d724 124 SUPERFAMILY SSF81301 18 123 1.12E-19 T 29-03-2018 THSYN_RS24825 e8ac17fdb77da060a530d9e2fbb7d724 124 Pfam PF01909 Nucleotidyltransferase domain 35 97 9.6E-12 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS24825 e8ac17fdb77da060a530d9e2fbb7d724 124 Gene3D G3DSA:3.30.460.10 5 124 1.3E-19 T 29-03-2018 THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 Gene3D G3DSA:3.40.50.300 220 397 3.1E-28 T 29-03-2018 THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 SUPERFAMILY SSF52540 225 468 3.71E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 Gene3D G3DSA:1.10.10.60 486 534 2.2E-12 T 29-03-2018 THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 439 448 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 Gene3D G3DSA:3.30.450.40 21 212 2.5E-14 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 SUPERFAMILY SSF55781 44 183 1.7E-14 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 Pfam PF00158 Sigma-54 interaction domain 226 393 1.8E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 250 263 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 312 327 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 SMART SM00065 42 193 9.3E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 SUPERFAMILY SSF46689 439 534 3.4E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 Gene3D G3DSA:1.10.8.60 399 471 5.7E-24 T 29-03-2018 THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 SMART SM00382 246 389 2.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS23300 433f06913e160c6abd98f028df467baa 557 Pfam PF02954 Bacterial regulatory protein, Fis family 488 532 1.1E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS09865 6011b5a61de24db43dae5e4d40ea3454 1075 SUPERFAMILY SSF52540 253 493 4.58E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09865 6011b5a61de24db43dae5e4d40ea3454 1075 Pfam PF04851 Type III restriction enzyme, res subunit 304 457 1.1E-14 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS09865 6011b5a61de24db43dae5e4d40ea3454 1075 SMART SM00487 294 484 7.7E-9 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS09865 6011b5a61de24db43dae5e4d40ea3454 1075 Gene3D G3DSA:3.40.50.300 38 479 3.8E-20 T 29-03-2018 THSYN_RS09865 6011b5a61de24db43dae5e4d40ea3454 1075 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 17 733 3.8E-132 T 29-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 THSYN_RS09865 6011b5a61de24db43dae5e4d40ea3454 1075 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 13 229 4.7E-31 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THSYN_RS32320 c8ee8dd4ec36ae6924cdc738a6378602 338 Gene3D G3DSA:3.90.1150.10 248 332 5.8E-7 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS32320 c8ee8dd4ec36ae6924cdc738a6378602 338 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 4 328 1.4E-105 T 29-03-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 THSYN_RS32320 c8ee8dd4ec36ae6924cdc738a6378602 338 SUPERFAMILY SSF53383 3 330 2.39E-56 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS32320 c8ee8dd4ec36ae6924cdc738a6378602 338 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 194 207 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 THSYN_RS32320 c8ee8dd4ec36ae6924cdc738a6378602 338 Pfam PF00155 Aminotransferase class I and II 51 281 2.5E-24 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THSYN_RS32320 c8ee8dd4ec36ae6924cdc738a6378602 338 Gene3D G3DSA:3.40.640.10 49 247 7.1E-30 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS15160 274c7db27bfcb8a1c1076913ebbf48cd 110 SUPERFAMILY SSF50118 3 108 4.8E-30 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS15160 274c7db27bfcb8a1c1076913ebbf48cd 110 Gene3D G3DSA:2.30.30.110 1 109 9.5E-26 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS15160 274c7db27bfcb8a1c1076913ebbf48cd 110 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 8 107 1.3E-21 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS29110 0538929664a2e8ba29a83502b9d07fc7 610 Pfam PF01380 SIS domain 464 592 2.9E-23 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 THSYN_RS29110 0538929664a2e8ba29a83502b9d07fc7 610 Pfam PF01380 SIS domain 295 419 2.1E-30 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 THSYN_RS29110 0538929664a2e8ba29a83502b9d07fc7 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 1.9E-255 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 THSYN_RS29110 0538929664a2e8ba29a83502b9d07fc7 610 Pfam PF13522 Glutamine amidotransferase domain 66 185 6.6E-20 T 29-03-2018 THSYN_RS29110 0538929664a2e8ba29a83502b9d07fc7 610 Gene3D G3DSA:3.40.50.10490 240 459 2.9E-59 T 29-03-2018 THSYN_RS29110 0538929664a2e8ba29a83502b9d07fc7 610 SUPERFAMILY SSF53697 246 610 2.85E-111 T 29-03-2018 THSYN_RS29110 0538929664a2e8ba29a83502b9d07fc7 610 Gene3D G3DSA:3.40.50.10490 460 608 2.0E-51 T 29-03-2018 THSYN_RS29110 0538929664a2e8ba29a83502b9d07fc7 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 40.375 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 THSYN_RS29110 0538929664a2e8ba29a83502b9d07fc7 610 Gene3D G3DSA:3.60.20.10 2 239 1.4E-64 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS29110 0538929664a2e8ba29a83502b9d07fc7 610 SUPERFAMILY SSF56235 2 234 1.97E-72 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS26855 2fd565e680e9f3701657f037b9684b4b 221 Pfam PF07788 PD-(D/E)XK nuclease superfamily 141 210 3.0E-24 T 29-03-2018 IPR012431 PD-(D/E)XK nuclease THSYN_RS26855 2fd565e680e9f3701657f037b9684b4b 221 Pfam PF12644 Protein of unknown function (DUF3782) 60 140 4.1E-24 T 29-03-2018 IPR024271 Protein of unknown function DUF3782 THSYN_RS05830 c4ac2db26e01339ce02ebd08741045fe 188 Hamap MF_00146 dCTP deaminase [dcd]. 1 188 28.471 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 THSYN_RS05830 c4ac2db26e01339ce02ebd08741045fe 188 Gene3D G3DSA:2.70.40.10 1 161 8.4E-59 T 29-03-2018 THSYN_RS05830 c4ac2db26e01339ce02ebd08741045fe 188 SUPERFAMILY SSF51283 3 187 3.01E-51 T 29-03-2018 IPR029054 dUTPase-like THSYN_RS05830 c4ac2db26e01339ce02ebd08741045fe 188 Pfam PF00692 dUTPase 76 184 8.3E-8 T 29-03-2018 IPR029054 dUTPase-like THSYN_RS05830 c4ac2db26e01339ce02ebd08741045fe 188 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 5 187 6.0E-49 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 THSYN_RS17180 ad0795ea6465d78cf3fad9014215228d 163 Pfam PF01909 Nucleotidyltransferase domain 65 133 2.6E-9 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS17180 ad0795ea6465d78cf3fad9014215228d 163 SUPERFAMILY SSF81301 60 162 1.94E-17 T 29-03-2018 THSYN_RS17180 ad0795ea6465d78cf3fad9014215228d 163 Gene3D G3DSA:3.30.460.10 44 163 5.5E-17 T 29-03-2018 THSYN_RS01155 01986effede0987a22b00628fda88b43 578 Pfam PF02470 MlaD protein 74 164 1.3E-13 T 29-03-2018 IPR003399 Mce/MlaD THSYN_RS01155 01986effede0987a22b00628fda88b43 578 Pfam PF02470 MlaD protein 190 265 4.9E-7 T 29-03-2018 IPR003399 Mce/MlaD THSYN_RS01155 01986effede0987a22b00628fda88b43 578 Pfam PF02470 MlaD protein 320 418 5.5E-12 T 29-03-2018 IPR003399 Mce/MlaD THSYN_RS10375 ddc997d4279d5ba4787d72c086a058cf 66 SUPERFAMILY SSF143800 1 65 7.06E-28 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS10375 ddc997d4279d5ba4787d72c086a058cf 66 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 64 28.559 T 29-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS10375 ddc997d4279d5ba4787d72c086a058cf 66 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 4.9E-34 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS10375 ddc997d4279d5ba4787d72c086a058cf 66 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 56 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS10375 ddc997d4279d5ba4787d72c086a058cf 66 Pfam PF01197 Ribosomal protein L31 1 65 5.7E-34 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS10375 ddc997d4279d5ba4787d72c086a058cf 66 PRINTS PR01249 Ribosomal protein L31 signature 46 64 1.3E-22 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS10375 ddc997d4279d5ba4787d72c086a058cf 66 PRINTS PR01249 Ribosomal protein L31 signature 31 46 1.3E-22 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS10375 ddc997d4279d5ba4787d72c086a058cf 66 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.3E-22 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 Pfam PF13484 4Fe-4S double cluster binding domain 698 767 3.5E-10 T 29-03-2018 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 Gene3D G3DSA:3.30.70.20 678 801 8.6E-27 T 29-03-2018 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 Gene3D G3DSA:3.40.50.970 4 260 3.9E-50 T 29-03-2018 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 Gene3D G3DSA:3.40.50.970 803 1185 2.5E-100 T 29-03-2018 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 7 1182 0.0 T 29-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 Gene3D G3DSA:3.40.920.10 424 634 6.1E-52 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 SUPERFAMILY SSF54862 674 849 4.6E-23 T 29-03-2018 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 SMART SM00890 631 688 1.6E-27 T 29-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 Gene3D G3DSA:3.40.50.920 261 423 2.8E-46 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 SUPERFAMILY SSF52518 804 1186 3.97E-123 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 SUPERFAMILY SSF52922 262 420 1.57E-42 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 Pfam PF10371 Domain of unknown function 635 687 4.3E-22 T 29-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 433 617 1.1E-25 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 Gene3D G3DSA:4.10.780.10 643 677 6.9E-13 T 29-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 755 766 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 271 356 2.1E-11 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 PIRSF PIRSF000159 2 1191 0.0 T 29-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 SUPERFAMILY SSF52518 7 260 1.35E-77 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 SUPERFAMILY SSF53323 424 677 2.22E-71 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 THSYN_RS04390 39b3b45bbd9df1077400188838fbd045 1199 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 23 249 6.1E-80 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 THSYN_RS22445 0a2cf5cb058631a9d25bbf74468fdc31 740 Pfam PF08351 Domain of unknown function (DUF1726) 70 158 5.4E-14 T 29-03-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 THSYN_RS22445 0a2cf5cb058631a9d25bbf74468fdc31 740 SUPERFAMILY SSF52540 192 335 6.13E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22445 0a2cf5cb058631a9d25bbf74468fdc31 740 Pfam PF13718 GNAT acetyltransferase 2 426 543 4.3E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS22445 0a2cf5cb058631a9d25bbf74468fdc31 740 Gene3D G3DSA:3.40.630.30 373 599 3.5E-18 T 29-03-2018 THSYN_RS22445 0a2cf5cb058631a9d25bbf74468fdc31 740 Gene3D G3DSA:3.40.50.300 188 369 5.0E-10 T 29-03-2018 THSYN_RS22445 0a2cf5cb058631a9d25bbf74468fdc31 740 Pfam PF05127 Helicase 219 391 3.4E-51 T 29-03-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 THSYN_RS22445 0a2cf5cb058631a9d25bbf74468fdc31 740 SUPERFAMILY SSF55729 442 573 2.09E-15 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS22445 0a2cf5cb058631a9d25bbf74468fdc31 740 Pfam PF17176 tRNA-binding domain 647 735 3.0E-8 T 29-03-2018 IPR033442 tRNA(Met) cytidine acetyltransferase TmcA, tRNA-binding domain KEGG: 00650+2.3.1.19 THSYN_RS22445 0a2cf5cb058631a9d25bbf74468fdc31 740 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 22 738 47.482 T 29-03-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 KEGG: 00650+2.3.1.19 THSYN_RS02350 ab0bed68bfb1423f8b26267bf623755d 496 Gene3D G3DSA:3.30.310.50 392 493 1.7E-15 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS02350 ab0bed68bfb1423f8b26267bf623755d 496 Gene3D G3DSA:3.40.120.10 189 267 2.1E-7 T 29-03-2018 THSYN_RS02350 ab0bed68bfb1423f8b26267bf623755d 496 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 13 138 1.9E-18 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS02350 ab0bed68bfb1423f8b26267bf623755d 496 SUPERFAMILY SSF53738 171 271 2.08E-11 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS02350 ab0bed68bfb1423f8b26267bf623755d 496 SUPERFAMILY SSF55957 423 492 4.71E-11 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS02350 ab0bed68bfb1423f8b26267bf623755d 496 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 274 393 9.5E-12 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS02350 ab0bed68bfb1423f8b26267bf623755d 496 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 424 483 6.3E-8 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS02350 ab0bed68bfb1423f8b26267bf623755d 496 Gene3D G3DSA:3.40.120.10 268 391 4.9E-17 T 29-03-2018 THSYN_RS02350 ab0bed68bfb1423f8b26267bf623755d 496 Gene3D G3DSA:3.40.120.10 7 146 3.2E-22 T 29-03-2018 THSYN_RS02350 ab0bed68bfb1423f8b26267bf623755d 496 SUPERFAMILY SSF53738 257 393 3.45E-8 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS02350 ab0bed68bfb1423f8b26267bf623755d 496 SUPERFAMILY SSF53738 10 143 5.89E-24 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS02350 ab0bed68bfb1423f8b26267bf623755d 496 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 104 113 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THSYN_RS00640 b89f3e6e7e9e16653de519bd6b776715 115 SUPERFAMILY SSF46785 31 104 1.06E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS00640 b89f3e6e7e9e16653de519bd6b776715 115 Pfam PF12840 Helix-turn-helix domain 44 99 1.2E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS00640 b89f3e6e7e9e16653de519bd6b776715 115 Gene3D G3DSA:1.10.10.10 9 111 1.0E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS29555 557db4701c36a552513565ecbbd09270 103 PIRSF PIRSF029218 1 99 1.8E-31 T 29-03-2018 IPR028344 Toxin-antitoxin system, toxin component ParE1/4 THSYN_RS29555 557db4701c36a552513565ecbbd09270 103 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 92 1.0E-19 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS29555 557db4701c36a552513565ecbbd09270 103 Gene3D G3DSA:3.30.2310.20 3 92 1.1E-4 T 29-03-2018 THSYN_RS24635 2a14913000f33fc33be7d9346e2556fa 158 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 3.9E-23 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24635 2a14913000f33fc33be7d9346e2556fa 158 SUPERFAMILY SSF56770 9 153 2.09E-68 T 29-03-2018 THSYN_RS24635 2a14913000f33fc33be7d9346e2556fa 158 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 2.8E-78 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24635 2a14913000f33fc33be7d9346e2556fa 158 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.932 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24635 2a14913000f33fc33be7d9346e2556fa 158 Gene3D G3DSA:3.40.50.700 11 156 4.8E-50 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24635 2a14913000f33fc33be7d9346e2556fa 158 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS10215 17e04a5b2a10f41932b6988b186f5fce 710 SUPERFAMILY SSF58104 444 708 5.89E-23 T 29-03-2018 THSYN_RS10215 17e04a5b2a10f41932b6988b186f5fce 710 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 539 674 3.1E-14 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THSYN_RS10215 17e04a5b2a10f41932b6988b186f5fce 710 SMART SM00283 450 708 4.0E-4 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THSYN_RS10215 17e04a5b2a10f41932b6988b186f5fce 710 Gene3D G3DSA:1.10.287.950 475 710 4.2E-18 T 29-03-2018 THSYN_RS17325 8a13f53b785c7d5cf3e3797751384140 1176 SUPERFAMILY SSF52540 246 457 1.73E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17325 8a13f53b785c7d5cf3e3797751384140 1176 Pfam PF00176 SNF2 family N-terminal domain 273 457 5.9E-13 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THSYN_RS17325 8a13f53b785c7d5cf3e3797751384140 1176 SUPERFAMILY SSF52540 654 827 9.68E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17325 8a13f53b785c7d5cf3e3797751384140 1176 SUPERFAMILY SSF52540 389 449 9.68E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17325 8a13f53b785c7d5cf3e3797751384140 1176 SMART SM00487 249 457 1.7E-8 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS17325 8a13f53b785c7d5cf3e3797751384140 1176 Gene3D G3DSA:3.40.50.300 645 1155 2.1E-24 T 29-03-2018 THSYN_RS17325 8a13f53b785c7d5cf3e3797751384140 1176 SMART SM00490 694 780 4.9E-11 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS17325 8a13f53b785c7d5cf3e3797751384140 1176 Pfam PF00271 Helicase conserved C-terminal domain 664 780 4.2E-14 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS17325 8a13f53b785c7d5cf3e3797751384140 1176 Gene3D G3DSA:3.40.50.10810 246 467 2.3E-25 T 29-03-2018 THSYN_RS02120 b700a9b6574a462e9c198518201ef412 101 SUPERFAMILY SSF52091 14 97 6.67E-13 T 29-03-2018 IPR002645 STAS domain THSYN_RS02120 b700a9b6574a462e9c198518201ef412 101 Gene3D G3DSA:3.30.750.24 11 100 9.5E-9 T 29-03-2018 IPR002645 STAS domain THSYN_RS02120 b700a9b6574a462e9c198518201ef412 101 Pfam PF13466 STAS domain 14 91 2.2E-16 T 29-03-2018 IPR002645 STAS domain THSYN_RS08690 20ccd288858c31928684d1dbbb3d956f 157 Gene3D G3DSA:2.60.40.790 5 139 7.2E-23 T 29-03-2018 IPR008978 HSP20-like chaperone THSYN_RS08690 20ccd288858c31928684d1dbbb3d956f 157 SUPERFAMILY SSF49764 11 139 2.58E-24 T 29-03-2018 IPR008978 HSP20-like chaperone THSYN_RS08690 20ccd288858c31928684d1dbbb3d956f 157 Pfam PF00011 Hsp20/alpha crystallin family 42 138 2.6E-20 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain THSYN_RS17820 cbc1c2b0cc21118e235583f89ef4cbee 267 SUPERFAMILY SSF51621 6 264 3.14E-101 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS17820 cbc1c2b0cc21118e235583f89ef4cbee 267 PIRSF PIRSF000388 2 267 1.5E-100 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 THSYN_RS17820 cbc1c2b0cc21118e235583f89ef4cbee 267 Gene3D G3DSA:3.20.20.60 1 267 1.2E-79 T 29-03-2018 THSYN_RS17820 cbc1c2b0cc21118e235583f89ef4cbee 267 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 6 267 42.42 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 THSYN_RS17820 cbc1c2b0cc21118e235583f89ef4cbee 267 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 12 263 3.7E-101 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 THSYN_RS17820 cbc1c2b0cc21118e235583f89ef4cbee 267 Pfam PF02548 Ketopantoate hydroxymethyltransferase 7 261 3.9E-108 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 THSYN_RS30935 87db14d77e1cb9ebc8200301559947ed 306 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 52 276 1.9E-110 T 29-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 THSYN_RS30935 87db14d77e1cb9ebc8200301559947ed 306 Gene3D G3DSA:3.40.50.300 9 296 8.6E-108 T 29-03-2018 THSYN_RS30935 87db14d77e1cb9ebc8200301559947ed 306 PIRSF PIRSF028756 14 306 2.8E-130 T 29-03-2018 IPR016898 Polyphosphate kinase 2 THSYN_RS30935 87db14d77e1cb9ebc8200301559947ed 306 SUPERFAMILY SSF52540 82 271 1.97E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30935 87db14d77e1cb9ebc8200301559947ed 306 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 51 275 1.3E-111 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related THSYN_RS05255 757c35f8c32f56c985ae83db55cd5740 386 Pfam PF00069 Protein kinase domain 38 145 5.2E-9 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS05255 757c35f8c32f56c985ae83db55cd5740 386 SUPERFAMILY SSF56112 31 148 1.89E-16 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS05255 757c35f8c32f56c985ae83db55cd5740 386 Gene3D G3DSA:1.10.510.10 21 318 1.9E-15 T 29-03-2018 THSYN_RS21065 6b7c368304018fa397e6127ff0d2c5b2 87 Pfam PF01649 Ribosomal protein S20 2 84 1.8E-27 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS21065 6b7c368304018fa397e6127ff0d2c5b2 87 SUPERFAMILY SSF46992 3 86 1.7E-30 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS21065 6b7c368304018fa397e6127ff0d2c5b2 87 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 1.6E-27 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS21065 6b7c368304018fa397e6127ff0d2c5b2 87 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 21 86 7.0E-19 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS21065 6b7c368304018fa397e6127ff0d2c5b2 87 Gene3D G3DSA:1.20.58.110 1 87 2.4E-29 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS21065 6b7c368304018fa397e6127ff0d2c5b2 87 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.368 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS12620 7026ebf1345eb662ac9cde0f88484eed 236 Gene3D G3DSA:3.40.50.300 2 234 3.9E-55 T 29-03-2018 THSYN_RS12620 7026ebf1345eb662ac9cde0f88484eed 236 SMART SM00382 35 223 1.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS12620 7026ebf1345eb662ac9cde0f88484eed 236 SUPERFAMILY SSF52540 7 227 5.84E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12620 7026ebf1345eb662ac9cde0f88484eed 236 Pfam PF00005 ABC transporter 26 174 1.3E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS12620 7026ebf1345eb662ac9cde0f88484eed 236 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 SUPERFAMILY SSF55347 150 314 5.66E-73 T 29-03-2018 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 2.7E-38 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 Gene3D G3DSA:3.30.360.10 161 316 1.4E-74 T 29-03-2018 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 PIRSF PIRSF000149 1 333 7.9E-128 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 314 2.1E-64 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 Gene3D G3DSA:3.40.50.720 1 160 6.6E-76 T 29-03-2018 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 326 2.6E-130 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 4.6E-45 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 4.6E-45 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 4.6E-45 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 4.6E-45 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 4.6E-45 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 SMART SM00846 3 151 1.3E-91 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 SUPERFAMILY SSF51735 3 167 6.48E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS04875 bfb382d2f6526760c29eda9bcd37c101 333 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS20115 983e278df8d0c10be2294a238763391e 158 Pfam PF00582 Universal stress protein family 6 151 2.1E-23 T 29-03-2018 IPR006016 UspA GO:0006950 THSYN_RS20115 983e278df8d0c10be2294a238763391e 158 PIRSF PIRSF006276 4 154 1.8E-26 T 29-03-2018 IPR006015 Universal stress protein A THSYN_RS20115 983e278df8d0c10be2294a238763391e 158 Gene3D G3DSA:3.40.50.620 5 154 2.4E-26 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS20115 983e278df8d0c10be2294a238763391e 158 SUPERFAMILY SSF52402 5 151 5.19E-27 T 29-03-2018 THSYN_RS20115 983e278df8d0c10be2294a238763391e 158 PRINTS PR01438 Universal stress protein signature 129 151 1.6E-11 T 29-03-2018 IPR006015 Universal stress protein A THSYN_RS20115 983e278df8d0c10be2294a238763391e 158 PRINTS PR01438 Universal stress protein signature 112 124 1.6E-11 T 29-03-2018 IPR006015 Universal stress protein A THSYN_RS20115 983e278df8d0c10be2294a238763391e 158 PRINTS PR01438 Universal stress protein signature 6 24 1.6E-11 T 29-03-2018 IPR006015 Universal stress protein A THSYN_RS01630 24666f53248e6b0afbad447a4c2ad5ad 89 Gene3D G3DSA:3.40.1620.10 2 55 5.6E-11 T 29-03-2018 THSYN_RS01630 24666f53248e6b0afbad447a4c2ad5ad 89 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 40 1.2E-7 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS01630 24666f53248e6b0afbad447a4c2ad5ad 89 SUPERFAMILY SSF143120 4 41 4.05E-6 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS01630 24666f53248e6b0afbad447a4c2ad5ad 89 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 41 2.3E-11 T 29-03-2018 THSYN_RS24180 effd4c1fdbbcc78c548e1dbaf5775352 952 Pfam PF00311 Phosphoenolpyruvate carboxylase 162 952 1.2E-272 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THSYN_RS24180 effd4c1fdbbcc78c548e1dbaf5775352 952 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 601 613 - T 29-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THSYN_RS24180 effd4c1fdbbcc78c548e1dbaf5775352 952 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 23 952 16.681 T 29-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THSYN_RS24180 effd4c1fdbbcc78c548e1dbaf5775352 952 Gene3D G3DSA:1.20.1440.90 305 436 6.1E-23 T 29-03-2018 THSYN_RS24180 effd4c1fdbbcc78c548e1dbaf5775352 952 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 163 174 - T 29-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THSYN_RS24180 effd4c1fdbbcc78c548e1dbaf5775352 952 SUPERFAMILY SSF51621 34 952 9.57E-277 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS24180 effd4c1fdbbcc78c548e1dbaf5775352 952 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 641 670 2.9E-59 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THSYN_RS24180 effd4c1fdbbcc78c548e1dbaf5775352 952 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 215 231 2.9E-59 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THSYN_RS24180 effd4c1fdbbcc78c548e1dbaf5775352 952 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 434 454 2.9E-59 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THSYN_RS24180 effd4c1fdbbcc78c548e1dbaf5775352 952 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 162 175 2.9E-59 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THSYN_RS24180 effd4c1fdbbcc78c548e1dbaf5775352 952 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 275 290 2.9E-59 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THSYN_RS24180 effd4c1fdbbcc78c548e1dbaf5775352 952 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 599 619 2.9E-59 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THSYN_RS24180 effd4c1fdbbcc78c548e1dbaf5775352 952 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 777 803 2.9E-59 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THSYN_RS07050 2f72895ad55196d9366c4ed80015b21f 522 SUPERFAMILY SSF53649 36 497 2.33E-107 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS07050 2f72895ad55196d9366c4ed80015b21f 522 Gene3D G3DSA:3.30.1120.10 402 492 4.8E-15 T 29-03-2018 THSYN_RS07050 2f72895ad55196d9366c4ed80015b21f 522 Gene3D G3DSA:3.40.720.10 35 256 6.5E-49 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS07050 2f72895ad55196d9366c4ed80015b21f 522 Gene3D G3DSA:3.40.720.10 257 401 1.5E-31 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS07050 2f72895ad55196d9366c4ed80015b21f 522 Pfam PF00884 Sulfatase 38 365 3.8E-64 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 520 531 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 SUPERFAMILY SSF46548 33 134 3.87E-21 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 Pfam PF00037 4Fe-4S binding domain 514 536 4.4E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 126 398 3.2E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 Gene3D G3DSA:3.50.50.60 219 268 5.5E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 Gene3D G3DSA:3.40.50.720 140 218 6.3E-18 T 29-03-2018 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 Gene3D G3DSA:3.30.70.20 500 542 9.0E-8 T 29-03-2018 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 34 111 1.3E-17 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 Gene3D G3DSA:3.90.180.10 117 139 0.11 T 29-03-2018 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 251 275 1.6E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 148 1.6E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 384 402 1.6E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 Gene3D G3DSA:3.50.50.60 269 432 1.7E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 SUPERFAMILY SSF51971 124 356 1.18E-51 T 29-03-2018 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 221 239 7.5E-19 T 29-03-2018 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 374 396 7.5E-19 T 29-03-2018 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 273 7.5E-19 T 29-03-2018 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 127 146 7.5E-19 T 29-03-2018 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 347 363 7.5E-19 T 29-03-2018 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 SUPERFAMILY SSF54862 453 540 2.8E-18 T 29-03-2018 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 SUPERFAMILY SSF54862 25 49 2.8E-18 T 29-03-2018 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 Gene3D G3DSA:1.10.1060.10 26 116 1.1E-25 T 29-03-2018 THSYN_RS07160 bb3457a461c0a4b6b08f2088809339f4 542 Gene3D G3DSA:1.10.1060.10 440 499 3.5E-8 T 29-03-2018 THSYN_RS13400 577aa3f60ff0513f1ef4e5b0fc75eb6a 235 SUPERFAMILY SSF51206 20 158 6.28E-25 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like THSYN_RS13400 577aa3f60ff0513f1ef4e5b0fc75eb6a 235 SMART SM00100 27 147 8.4E-9 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS13400 577aa3f60ff0513f1ef4e5b0fc75eb6a 235 Pfam PF00027 Cyclic nucleotide-binding domain 47 128 3.0E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS13400 577aa3f60ff0513f1ef4e5b0fc75eb6a 235 Gene3D G3DSA:2.60.120.10 19 159 7.3E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS13400 577aa3f60ff0513f1ef4e5b0fc75eb6a 235 Pfam PF13545 Crp-like helix-turn-helix domain 164 232 7.1E-14 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS13400 577aa3f60ff0513f1ef4e5b0fc75eb6a 235 SUPERFAMILY SSF46785 161 234 1.26E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS13400 577aa3f60ff0513f1ef4e5b0fc75eb6a 235 Gene3D G3DSA:1.10.10.10 160 233 2.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS30940 deb0a4e91e4db24f568eb56e55e812d6 317 SUPERFAMILY SSF53474 26 313 1.6E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS30940 deb0a4e91e4db24f568eb56e55e812d6 317 Pfam PF05448 Acetyl xylan esterase (AXE1) 18 298 6.4E-16 T 29-03-2018 IPR008391 Acetyl xylan esterase THSYN_RS30940 deb0a4e91e4db24f568eb56e55e812d6 317 Gene3D G3DSA:3.40.50.1820 20 315 1.0E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 220 259 1.1E-6 T 29-03-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 Gene3D G3DSA:2.60.120.430 1053 1174 1.1E-6 T 29-03-2018 THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 Pfam PF13229 Right handed beta helix region 125 266 7.0E-16 T 29-03-2018 THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 SUPERFAMILY SSF51126 14 317 8.59E-34 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 SUPERFAMILY SSF51126 368 421 8.59E-34 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 Gene3D G3DSA:3.90.182.10 580 645 5.3E-6 T 29-03-2018 THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 Gene3D G3DSA:2.60.120.260 831 985 2.2E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 Gene3D G3DSA:2.60.120.430 1177 1365 4.9E-11 T 29-03-2018 THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 Gene3D G3DSA:2.160.20.10 24 579 8.4E-41 T 29-03-2018 IPR012334 Pectin lyase fold THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 SMART SM00710 223 244 19.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 SMART SM00710 97 119 3900.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 SMART SM00710 245 267 530.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 SMART SM00710 829 860 9000.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 SMART SM00710 170 192 21.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 SMART SM00710 297 317 10000.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 SMART SM00710 122 143 11.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 SMART SM00710 322 347 4400.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 SUPERFAMILY SSF49785 1189 1290 5.53E-13 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS16090 493395657dc182bfb194ca6b426250e6 1915 SUPERFAMILY SSF49785 1320 1361 5.53E-13 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS22735 b573a2367ebc36e5d0bed02124c88d05 332 Gene3D G3DSA:3.90.550.10 1 304 8.6E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22735 b573a2367ebc36e5d0bed02124c88d05 332 SUPERFAMILY SSF53448 1 237 2.97E-34 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22735 b573a2367ebc36e5d0bed02124c88d05 332 Pfam PF00535 Glycosyl transferase family 2 5 109 2.7E-20 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 SUPERFAMILY SSF82693 47 131 9.07E-19 T 29-03-2018 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 SUPERFAMILY SSF82714 769 856 3.27E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 Pfam PF00873 AcrB/AcrD/AcrF family 20 520 1.5E-88 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 Pfam PF00873 AcrB/AcrD/AcrF family 576 1081 5.1E-65 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 SUPERFAMILY SSF82693 291 346 2.49E-11 T 29-03-2018 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 SUPERFAMILY SSF82693 151 191 2.49E-11 T 29-03-2018 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 Gene3D G3DSA:3.30.70.1430 47 150 1.5E-21 T 29-03-2018 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 Gene3D G3DSA:1.20.1640.10 291 517 1.1E-32 T 29-03-2018 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 Gene3D G3DSA:1.20.1640.10 901 1088 1.6E-32 T 29-03-2018 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 SUPERFAMILY SSF82866 858 1083 1.31E-40 T 29-03-2018 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 SUPERFAMILY SSF82693 607 721 1.18E-12 T 29-03-2018 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 SUPERFAMILY SSF82714 194 275 2.49E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 PRINTS PR00702 Acriflavin resistance protein family signature 487 510 2.8E-26 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 PRINTS PR00702 Acriflavin resistance protein family signature 408 432 2.8E-26 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 2.8E-26 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 PRINTS PR00702 Acriflavin resistance protein family signature 45 63 2.8E-26 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 PRINTS PR00702 Acriflavin resistance protein family signature 17 41 2.8E-26 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 PRINTS PR00702 Acriflavin resistance protein family signature 354 377 2.8E-26 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 Gene3D G3DSA:3.30.2090.10 767 859 3.8E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 Gene3D G3DSA:3.30.2090.10 190 278 2.0E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 Gene3D G3DSA:3.30.70.1430 609 720 6.5E-19 T 29-03-2018 THSYN_RS02260 58349c3d0d37e4133688e4d46589cd4e 1096 SUPERFAMILY SSF82866 313 512 1.14E-34 T 29-03-2018 THSYN_RS04070 4cecc422928960d7e4d706c3af4b4726 447 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 19 432 3.9E-114 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 THSYN_RS04070 4cecc422928960d7e4d706c3af4b4726 447 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 22 437 7.9E-118 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THSYN_RS04070 4cecc422928960d7e4d706c3af4b4726 447 Gene3D G3DSA:3.65.10.10 230 444 3.9E-51 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 THSYN_RS04070 4cecc422928960d7e4d706c3af4b4726 447 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 18 441 31.858 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THSYN_RS04070 4cecc422928960d7e4d706c3af4b4726 447 PIRSF PIRSF000505 10 444 7.8E-114 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THSYN_RS04070 4cecc422928960d7e4d706c3af4b4726 447 Gene3D G3DSA:3.65.10.10 29 229 2.0E-47 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 THSYN_RS04070 4cecc422928960d7e4d706c3af4b4726 447 ProSitePatterns PS00885 EPSP synthase signature 2. 353 371 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THSYN_RS04070 4cecc422928960d7e4d706c3af4b4726 447 SUPERFAMILY SSF55205 18 439 9.48E-122 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 THSYN_RS04070 4cecc422928960d7e4d706c3af4b4726 447 ProSitePatterns PS00104 EPSP synthase signature 1. 97 111 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THSYN_RS18680 81eb52d1acd086a9f2d4b66919b9dee8 65 Pfam PF14076 Domain of unknown function (DUF4258) 1 63 3.7E-8 T 29-03-2018 IPR025354 Protein of unknown function DUF4258 THSYN_RS22420 894d252c7c701fa66ef8ce9b00561fdc 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 156 1.6E-55 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 THSYN_RS22420 894d252c7c701fa66ef8ce9b00561fdc 158 PIRSF PIRSF006092 1 158 5.4E-51 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 THSYN_RS22420 894d252c7c701fa66ef8ce9b00561fdc 158 SUPERFAMILY SSF54534 82 157 1.83E-22 T 29-03-2018 THSYN_RS22420 894d252c7c701fa66ef8ce9b00561fdc 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 32.96 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 THSYN_RS22420 894d252c7c701fa66ef8ce9b00561fdc 158 Gene3D G3DSA:3.10.50.30 77 158 1.6E-26 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 THSYN_RS22420 894d252c7c701fa66ef8ce9b00561fdc 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 4.4E-31 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 THSYN_RS22420 894d252c7c701fa66ef8ce9b00561fdc 158 SUPERFAMILY SSF46557 3 78 6.41E-29 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 THSYN_RS22420 894d252c7c701fa66ef8ce9b00561fdc 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 THSYN_RS22420 894d252c7c701fa66ef8ce9b00561fdc 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 82 157 9.7E-27 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 THSYN_RS22420 894d252c7c701fa66ef8ce9b00561fdc 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 THSYN_RS22420 894d252c7c701fa66ef8ce9b00561fdc 158 Gene3D G3DSA:1.10.287.180 3 76 4.3E-32 T 29-03-2018 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 Gene3D G3DSA:3.30.980.10 66 141 1.5E-21 T 29-03-2018 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 Gene3D G3DSA:3.40.50.800 535 640 2.0E-25 T 29-03-2018 IPR004154 Anticodon-binding THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 325 531 1.2E-42 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 466 494 2.3E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 536 548 2.3E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 364 387 2.3E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 331 359 2.3E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 509 522 2.3E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 SMART SM00863 171 221 1.4E-24 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 171 221 3.3E-14 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 SUPERFAMILY SSF81271 3 61 5.01E-15 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 SUPERFAMILY SSF55681 245 528 3.19E-94 T 29-03-2018 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 Gene3D G3DSA:3.30.54.20 142 188 1.0E-21 T 29-03-2018 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 Gene3D G3DSA:3.30.930.10 223 533 1.9E-117 T 29-03-2018 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 SUPERFAMILY SSF52954 529 634 2.72E-29 T 29-03-2018 IPR004154 Anticodon-binding THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 67 636 34.717 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 73 632 1.2E-221 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 Gene3D G3DSA:3.10.20.30 1 64 4.4E-18 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 SUPERFAMILY SSF55186 65 243 6.54E-67 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 Pfam PF02824 TGS domain 4 61 2.1E-10 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 THSYN_RS24020 2f81e5c5c5cd3f7c102c9a06063ecbf6 640 Pfam PF03129 Anticodon binding domain 543 629 3.7E-19 T 29-03-2018 IPR004154 Anticodon-binding THSYN_RS22005 22e35d1d0581b7e473eda07268936ace 448 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 9 447 1.1E-111 T 29-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 THSYN_RS22005 22e35d1d0581b7e473eda07268936ace 448 Pfam PF13180 PDZ domain 215 289 1.2E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS22005 22e35d1d0581b7e473eda07268936ace 448 SUPERFAMILY SSF50156 209 295 7.49E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS22005 22e35d1d0581b7e473eda07268936ace 448 SUPERFAMILY SSF50156 90 188 5.78E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS22005 22e35d1d0581b7e473eda07268936ace 448 Gene3D G3DSA:2.30.42.10 223 308 2.3E-19 T 29-03-2018 THSYN_RS22005 22e35d1d0581b7e473eda07268936ace 448 Gene3D G3DSA:2.30.42.10 128 219 4.6E-10 T 29-03-2018 THSYN_RS22005 22e35d1d0581b7e473eda07268936ace 448 Pfam PF02163 Peptidase family M50 11 433 1.5E-76 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 THSYN_RS22005 22e35d1d0581b7e473eda07268936ace 448 SMART SM00228 213 282 8.2E-9 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS22005 22e35d1d0581b7e473eda07268936ace 448 SMART SM00228 117 189 4.7E-5 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS31340 22444a8887fa2f4dce69271819a58245 289 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 77 93 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site THSYN_RS31340 22444a8887fa2f4dce69271819a58245 289 SUPERFAMILY SSF48576 19 263 4.5E-61 T 29-03-2018 IPR008949 Isoprenoid synthase domain THSYN_RS31340 22444a8887fa2f4dce69271819a58245 289 Pfam PF00348 Polyprenyl synthetase 27 238 1.9E-42 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 THSYN_RS31340 22444a8887fa2f4dce69271819a58245 289 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 200 212 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site THSYN_RS31340 22444a8887fa2f4dce69271819a58245 289 Gene3D G3DSA:1.10.600.10 1 278 2.1E-58 T 29-03-2018 IPR008949 Isoprenoid synthase domain THSYN_RS23735 c98ee4502805881935beda87926804f1 505 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 211 497 5.2E-56 T 29-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family THSYN_RS23735 c98ee4502805881935beda87926804f1 505 Pfam PF16868 NMT1-like family 218 497 5.9E-45 T 29-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family THSYN_RS23735 c98ee4502805881935beda87926804f1 505 Gene3D G3DSA:3.40.190.10 212 322 1.5E-9 T 29-03-2018 THSYN_RS23735 c98ee4502805881935beda87926804f1 505 Gene3D G3DSA:3.40.190.10 323 500 2.7E-22 T 29-03-2018 THSYN_RS23735 c98ee4502805881935beda87926804f1 505 SUPERFAMILY SSF53850 215 497 2.88E-52 T 29-03-2018 THSYN_RS31170 2378638ca720e6e1edef2c3dfebcee9e 270 Gene3D G3DSA:3.60.21.10 13 250 2.8E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS31170 2378638ca720e6e1edef2c3dfebcee9e 270 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 15 228 1.2E-11 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 THSYN_RS31170 2378638ca720e6e1edef2c3dfebcee9e 270 SUPERFAMILY SSF56300 13 133 2.22E-30 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS31170 2378638ca720e6e1edef2c3dfebcee9e 270 SUPERFAMILY SSF56300 189 250 2.22E-30 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS13240 3d914490f557d6c61b5b2fef3fb651c8 187 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THSYN_RS13240 3d914490f557d6c61b5b2fef3fb651c8 187 Gene3D G3DSA:3.90.79.10 5 186 1.4E-32 T 29-03-2018 THSYN_RS13240 3d914490f557d6c61b5b2fef3fb651c8 187 SUPERFAMILY SSF55811 5 175 1.07E-35 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 THSYN_RS13240 3d914490f557d6c61b5b2fef3fb651c8 187 Pfam PF00293 NUDIX domain 45 162 9.3E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THSYN_RS23975 a50876f8c1156891d513b302d2f925ae 65 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 8 61 8.7E-9 T 29-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 THSYN_RS23975 a50876f8c1156891d513b302d2f925ae 65 SUPERFAMILY SSF54786 7 62 1.33E-9 T 29-03-2018 THSYN_RS23975 a50876f8c1156891d513b302d2f925ae 65 Gene3D G3DSA:3.30.920.30 6 61 1.2E-11 T 29-03-2018 THSYN_RS24920 989353535ad8e03241641802ead8937a 243 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 82 96 - T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein THSYN_RS24920 989353535ad8e03241641802ead8937a 243 Pfam PF01168 Alanine racemase, N-terminal domain 13 233 1.4E-28 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THSYN_RS24920 989353535ad8e03241641802ead8937a 243 Gene3D G3DSA:3.20.20.10 1 241 3.1E-65 T 29-03-2018 IPR029066 PLP-binding barrel THSYN_RS24920 989353535ad8e03241641802ead8937a 243 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 11 232 4.3E-58 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein THSYN_RS24920 989353535ad8e03241641802ead8937a 243 PIRSF PIRSF004848 1 237 1.4E-61 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein THSYN_RS24920 989353535ad8e03241641802ead8937a 243 SUPERFAMILY SSF51419 9 230 2.75E-70 T 29-03-2018 IPR029066 PLP-binding barrel THSYN_RS11625 7f9612774e559a0a1cfb74832726c63c 347 SMART SM00729 48 254 1.7E-30 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS11625 7f9612774e559a0a1cfb74832726c63c 347 SMART SM00876 225 317 1.2E-38 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THSYN_RS11625 7f9612774e559a0a1cfb74832726c63c 347 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 225 315 1.6E-16 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THSYN_RS11625 7f9612774e559a0a1cfb74832726c63c 347 Pfam PF04055 Radical SAM superfamily 55 208 3.6E-12 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS11625 7f9612774e559a0a1cfb74832726c63c 347 Gene3D G3DSA:3.20.20.70 9 320 1.4E-55 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS11625 7f9612774e559a0a1cfb74832726c63c 347 PIRSF PIRSF001619 2 323 5.5E-122 T 29-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THSYN_RS11625 7f9612774e559a0a1cfb74832726c63c 347 TIGRFAM TIGR00433 bioB: biotin synthase 22 315 1.4E-116 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THSYN_RS11625 7f9612774e559a0a1cfb74832726c63c 347 SUPERFAMILY SSF102114 10 315 5.1E-88 T 29-03-2018 THSYN_RS11625 7f9612774e559a0a1cfb74832726c63c 347 Hamap MF_01694 Biotin synthase [bioB]. 10 318 40.78 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THSYN_RS28450 4f1fea56303be542c0aad81d7992560f 596 Pfam PF00374 Nickel-dependent hydrogenase 53 581 8.2E-230 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THSYN_RS28450 4f1fea56303be542c0aad81d7992560f 596 SUPERFAMILY SSF56762 11 581 2.22E-179 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS28450 4f1fea56303be542c0aad81d7992560f 596 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 53 78 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THSYN_RS28450 4f1fea56303be542c0aad81d7992560f 596 Gene3D G3DSA:1.10.645.10 12 581 5.5E-199 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS28450 4f1fea56303be542c0aad81d7992560f 596 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 572 581 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THSYN_RS29005 4e25c88bcc44ca3b64ac9601730db222 249 SUPERFAMILY SSF53448 6 245 6.99E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS29005 4e25c88bcc44ca3b64ac9601730db222 249 Pfam PF00535 Glycosyl transferase family 2 17 187 3.9E-21 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS29005 4e25c88bcc44ca3b64ac9601730db222 249 Gene3D G3DSA:3.90.550.10 1 248 2.1E-34 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS27835 79367c2882707c67da5398b8bf9e962e 548 Gene3D G3DSA:3.40.50.1820 76 529 1.2E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS27835 79367c2882707c67da5398b8bf9e962e 548 SUPERFAMILY SSF53474 95 151 4.63E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS27835 79367c2882707c67da5398b8bf9e962e 548 SUPERFAMILY SSF53474 385 527 4.63E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS27835 79367c2882707c67da5398b8bf9e962e 548 SUPERFAMILY SSF53474 204 258 4.63E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS27835 79367c2882707c67da5398b8bf9e962e 548 Pfam PF08386 TAP-like protein 450 539 1.9E-20 T 29-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal THSYN_RS27835 79367c2882707c67da5398b8bf9e962e 548 Pfam PF00561 alpha/beta hydrolase fold 103 260 3.4E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS31740 32fe2b43e1dd74a54a10aa57453bf49a 409 Gene3D G3DSA:1.20.1600.10 51 358 3.9E-14 T 29-03-2018 THSYN_RS31740 32fe2b43e1dd74a54a10aa57453bf49a 409 SUPERFAMILY SSF111369 206 251 3.4E-5 T 29-03-2018 THSYN_RS31740 32fe2b43e1dd74a54a10aa57453bf49a 409 SUPERFAMILY SSF111369 71 154 3.4E-5 T 29-03-2018 THSYN_RS31740 32fe2b43e1dd74a54a10aa57453bf49a 409 Pfam PF13533 Biotin-lipoyl like 74 122 6.7E-9 T 29-03-2018 THSYN_RS15090 ce07e4644b44ea246aa6cbf03f737807 292 Pfam PF01040 UbiA prenyltransferase family 26 250 7.0E-20 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 THSYN_RS16495 d41d6b1e77fdf90756ff345eea3eafc2 966 Gene3D G3DSA:2.40.40.20 761 935 4.5E-37 T 29-03-2018 THSYN_RS16495 d41d6b1e77fdf90756ff345eea3eafc2 966 Gene3D G3DSA:3.40.228.10 504 722 8.3E-5 T 29-03-2018 THSYN_RS16495 d41d6b1e77fdf90756ff345eea3eafc2 966 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 17 68 1.7E-16 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS16495 d41d6b1e77fdf90756ff345eea3eafc2 966 Gene3D G3DSA:3.40.228.10 146 436 3.0E-62 T 29-03-2018 THSYN_RS16495 d41d6b1e77fdf90756ff345eea3eafc2 966 SMART SM00926 15 69 7.7E-19 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS16495 d41d6b1e77fdf90756ff345eea3eafc2 966 Gene3D G3DSA:2.20.25.90 8 74 1.3E-18 T 29-03-2018 THSYN_RS16495 d41d6b1e77fdf90756ff345eea3eafc2 966 SUPERFAMILY SSF50692 781 931 2.49E-31 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain THSYN_RS16495 d41d6b1e77fdf90756ff345eea3eafc2 966 Pfam PF00384 Molybdopterin oxidoreductase 72 367 6.6E-20 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS16495 d41d6b1e77fdf90756ff345eea3eafc2 966 Pfam PF00384 Molybdopterin oxidoreductase 547 623 1.3E-7 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS16495 d41d6b1e77fdf90756ff345eea3eafc2 966 SUPERFAMILY SSF53706 15 749 1.83E-147 T 29-03-2018 THSYN_RS16495 d41d6b1e77fdf90756ff345eea3eafc2 966 Pfam PF01568 Molydopterin dinucleotide binding domain 789 892 4.4E-10 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 THSYN_RS12045 bf6fcb71753c00fd3e73b1505fbd86c2 855 Gene3D G3DSA:3.20.20.70 56 365 8.1E-28 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS12045 bf6fcb71753c00fd3e73b1505fbd86c2 855 SUPERFAMILY SSF102114 504 803 1.57E-26 T 29-03-2018 THSYN_RS12045 bf6fcb71753c00fd3e73b1505fbd86c2 855 SUPERFAMILY SSF102114 58 375 2.09E-35 T 29-03-2018 THSYN_RS12045 bf6fcb71753c00fd3e73b1505fbd86c2 855 Gene3D G3DSA:3.20.20.70 490 703 7.2E-18 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS12045 bf6fcb71753c00fd3e73b1505fbd86c2 855 Pfam PF13394 4Fe-4S single cluster domain 514 594 3.5E-6 T 29-03-2018 THSYN_RS12045 bf6fcb71753c00fd3e73b1505fbd86c2 855 Pfam PF04055 Radical SAM superfamily 61 205 7.3E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS12045 bf6fcb71753c00fd3e73b1505fbd86c2 855 Pfam PF04055 Radical SAM superfamily 516 624 4.3E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS12045 bf6fcb71753c00fd3e73b1505fbd86c2 855 TIGRFAM TIGR04083 rSAM_pep_methan: putative peptide-modifying radical SAM enzyme, Mhun_1560 family 56 415 4.6E-97 T 29-03-2018 IPR024018 Conserved hypothetical protein CHP04083, radical SAM THSYN_RS12045 bf6fcb71753c00fd3e73b1505fbd86c2 855 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 302 392 3.0E-16 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain THSYN_RS19375 cbc4d114b330cd2f531b9f9cd2898bfc 168 SUPERFAMILY SSF52949 4 167 3.2E-59 T 29-03-2018 THSYN_RS19375 cbc4d114b330cd2f531b9f9cd2898bfc 168 SMART SM00506 4 133 7.9E-41 T 29-03-2018 IPR002589 Macro domain THSYN_RS19375 cbc4d114b330cd2f531b9f9cd2898bfc 168 Gene3D G3DSA:3.40.220.10 3 168 1.7E-65 T 29-03-2018 THSYN_RS19375 cbc4d114b330cd2f531b9f9cd2898bfc 168 Pfam PF01661 Macro domain 21 133 8.1E-41 T 29-03-2018 IPR002589 Macro domain THSYN_RS28890 974cde8231a22d91777bac4913273f6b 726 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 170 3.2E-24 T 29-03-2018 THSYN_RS28890 974cde8231a22d91777bac4913273f6b 726 Gene3D G3DSA:3.30.565.10 562 724 9.4E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS28890 974cde8231a22d91777bac4913273f6b 726 SMART SM00387 607 726 4.3E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS28890 974cde8231a22d91777bac4913273f6b 726 SUPERFAMILY SSF55874 13 177 3.54E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS28890 974cde8231a22d91777bac4913273f6b 726 Gene3D G3DSA:3.30.565.10 2 218 7.6E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS28890 974cde8231a22d91777bac4913273f6b 726 SUPERFAMILY SSF55874 596 709 4.19E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS14315 538d0ec1f25fde6310ee563e0c2b833f 167 SUPERFAMILY SSF52788 8 144 2.88E-37 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS14315 538d0ec1f25fde6310ee563e0c2b833f 167 Gene3D G3DSA:3.40.50.2300 4 144 4.0E-36 T 29-03-2018 THSYN_RS14315 538d0ec1f25fde6310ee563e0c2b833f 167 SMART SM00226 7 144 8.0E-38 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS14315 538d0ec1f25fde6310ee563e0c2b833f 167 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 10 142 2.6E-19 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 SUPERFAMILY SSF52540 265 520 4.0E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 Gene3D G3DSA:1.10.150.200 936 977 4.8E-9 T 29-03-2018 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 Gene3D G3DSA:1.10.150.200 879 935 4.0E-7 T 29-03-2018 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 Gene3D G3DSA:1.25.40.10 709 822 9.8E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 Gene3D G3DSA:3.40.50.300 258 433 1.3E-10 T 29-03-2018 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 Gene3D G3DSA:1.25.40.10 978 1043 8.4E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 Pfam PF12770 CHAT domain 59 209 5.9E-14 T 29-03-2018 IPR024983 CHAT domain THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 Gene3D G3DSA:3.40.50.1460 29 221 3.8E-20 T 29-03-2018 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 SMART SM00028 849 882 16.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 SMART SM00028 889 922 20.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 SMART SM00028 809 842 24.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 SMART SM00028 929 963 99.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 SMART SM00028 970 1003 21.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 Pfam PF13424 Tetratricopeptide repeat 848 918 1.9E-9 T 29-03-2018 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 SUPERFAMILY SSF48452 852 1037 5.82E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 SUPERFAMILY SSF48452 759 881 1.05E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS11475 3b9f275de878fb550772f8110555b10f 1135 Gene3D G3DSA:1.25.40.10 823 878 4.5E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS05435 94ad8839cbb6041d78421ccca41d2c60 462 SMART SM00382 22 382 9.7E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS05435 94ad8839cbb6041d78421ccca41d2c60 462 SUPERFAMILY SSF52540 268 376 1.44E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05435 94ad8839cbb6041d78421ccca41d2c60 462 SUPERFAMILY SSF52540 1 183 1.44E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05435 94ad8839cbb6041d78421ccca41d2c60 462 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 25 361 2.5E-18 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS05435 94ad8839cbb6041d78421ccca41d2c60 462 Gene3D G3DSA:3.40.50.300 1 377 2.7E-29 T 29-03-2018 THSYN_RS29085 84f4a5ab3e7decab2b2ece174cd9b713 137 Gene3D G3DSA:3.10.450.50 20 136 0.0015 T 29-03-2018 THSYN_RS29085 84f4a5ab3e7decab2b2ece174cd9b713 137 SUPERFAMILY SSF54427 28 135 9.35E-5 T 29-03-2018 IPR032710 NTF2-like domain THSYN_RS20785 119c055e8a36c5c8fd752c58d05b0f5c 222 Gene3D G3DSA:3.40.50.850 3 217 1.7E-48 T 29-03-2018 THSYN_RS20785 119c055e8a36c5c8fd752c58d05b0f5c 222 Pfam PF00857 Isochorismatase family 19 206 2.6E-41 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THSYN_RS20785 119c055e8a36c5c8fd752c58d05b0f5c 222 SUPERFAMILY SSF52499 5 207 9.29E-52 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THSYN_RS13515 448da76e2aa96c9d695dc7300c764328 1081 SUPERFAMILY SSF53335 217 259 2.17E-7 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS13515 448da76e2aa96c9d695dc7300c764328 1081 Pfam PF01555 DNA methylase 669 767 4.1E-5 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THSYN_RS13515 448da76e2aa96c9d695dc7300c764328 1081 SUPERFAMILY SSF53335 661 684 1.43E-12 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS13515 448da76e2aa96c9d695dc7300c764328 1081 SUPERFAMILY SSF53335 729 816 1.43E-12 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS13515 448da76e2aa96c9d695dc7300c764328 1081 Pfam PF06634 Protein of unknown function (DUF1156) 19 65 7.3E-13 T 29-03-2018 IPR009537 Domain of unknown function DUF1156 THSYN_RS13515 448da76e2aa96c9d695dc7300c764328 1081 Gene3D G3DSA:3.40.50.150 112 817 3.5E-37 T 29-03-2018 THSYN_RS25965 77a5466766ccc74461a647cc05f7ab41 237 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 7 230 1.2E-72 T 29-03-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 THSYN_RS25965 77a5466766ccc74461a647cc05f7ab41 237 Gene3D G3DSA:3.40.50.300 11 163 1.9E-14 T 29-03-2018 THSYN_RS25965 77a5466766ccc74461a647cc05f7ab41 237 Gene3D G3DSA:1.10.8.60 170 231 3.2E-7 T 29-03-2018 THSYN_RS25965 77a5466766ccc74461a647cc05f7ab41 237 Pfam PF00308 Bacterial dnaA protein 91 197 2.9E-9 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA THSYN_RS25965 77a5466766ccc74461a647cc05f7ab41 237 SMART SM00382 43 160 0.0021 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS25965 77a5466766ccc74461a647cc05f7ab41 237 SUPERFAMILY SSF52540 42 211 1.94E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15525 2b9ee03f416a13f267437cb2d9dd0ddc 1769 Pfam PF13699 Domain of unknown function (DUF4157) 118 190 1.4E-22 T 29-03-2018 IPR025295 Domain of unknown function DUF4157 THSYN_RS15525 2b9ee03f416a13f267437cb2d9dd0ddc 1769 Gene3D G3DSA:1.20.120.20 608 812 2.3E-7 T 29-03-2018 THSYN_RS15525 2b9ee03f416a13f267437cb2d9dd0ddc 1769 Gene3D G3DSA:1.20.120.20 364 493 2.9E-5 T 29-03-2018 THSYN_RS15525 2b9ee03f416a13f267437cb2d9dd0ddc 1769 Gene3D G3DSA:1.20.120.20 495 607 4.9E-9 T 29-03-2018 THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 Pfam PF17210 SdrD B-like domain 1107 1171 1.1E-6 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 Pfam PF17210 SdrD B-like domain 780 846 1.2E-6 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 Pfam PF17210 SdrD B-like domain 624 693 9.6E-7 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 Pfam PF17210 SdrD B-like domain 1463 1543 1.2E-8 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 Pfam PF17210 SdrD B-like domain 467 535 2.2E-7 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 Pfam PF17210 SdrD B-like domain 937 1005 4.2E-11 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 Gene3D G3DSA:2.60.40.10 464 618 2.0E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 Gene3D G3DSA:2.60.40.10 775 932 6.8E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 Gene3D G3DSA:2.60.40.10 1461 1678 7.3E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 Gene3D G3DSA:2.60.40.10 1269 1453 2.1E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 Gene3D G3DSA:2.60.40.10 1103 1257 1.6E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 Gene3D G3DSA:2.60.40.10 933 1097 4.0E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 SUPERFAMILY SSF117074 1081 1169 7.19E-10 T 29-03-2018 THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 SUPERFAMILY SSF117074 755 846 5.36E-9 T 29-03-2018 THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 SUPERFAMILY SSF117074 1249 1352 1.83E-10 T 29-03-2018 THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 SUPERFAMILY SSF49478 490 538 1.33E-8 T 29-03-2018 THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 SUPERFAMILY SSF117074 1437 1543 2.09E-11 T 29-03-2018 THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 Gene3D G3DSA:2.60.40.1120 621 732 4.9E-8 T 29-03-2018 THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 SUPERFAMILY SSF117074 598 693 6.54E-11 T 29-03-2018 THSYN_RS24550 8f96c981271f0a99db7538a207986540 1734 SUPERFAMILY SSF117074 913 1000 3.79E-13 T 29-03-2018 THSYN_RS07125 d3d8ba445974292fb1672abcde970c37 294 Pfam PF13493 Domain of unknown function (DUF4118) 38 141 1.3E-16 T 29-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain THSYN_RS07125 d3d8ba445974292fb1672abcde970c37 294 Gene3D G3DSA:3.30.450.20 153 288 4.7E-23 T 29-03-2018 THSYN_RS07125 d3d8ba445974292fb1672abcde970c37 294 Gene3D G3DSA:1.20.120.620 37 135 6.8E-14 T 29-03-2018 THSYN_RS07125 d3d8ba445974292fb1672abcde970c37 294 Pfam PF00989 PAS fold 175 287 1.2E-11 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS07125 d3d8ba445974292fb1672abcde970c37 294 SUPERFAMILY SSF55785 160 287 1.31E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS07125 d3d8ba445974292fb1672abcde970c37 294 SMART SM00091 172 241 3.8E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS07125 d3d8ba445974292fb1672abcde970c37 294 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 174 287 1.6E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS26110 160a4700ec806866d632d934cacf40dc 408 Pfam PF03781 Sulfatase-modifying factor enzyme 1 215 366 2.0E-29 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS26110 160a4700ec806866d632d934cacf40dc 408 Gene3D G3DSA:3.90.1580.10 206 374 1.1E-30 T 29-03-2018 THSYN_RS26110 160a4700ec806866d632d934cacf40dc 408 Gene3D G3DSA:3.40.50.9200 1 88 5.8E-4 T 29-03-2018 THSYN_RS26110 160a4700ec806866d632d934cacf40dc 408 SUPERFAMILY SSF56436 212 366 2.07E-34 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS02780 1fa52fa7687bc26442bfa86748385f60 275 ProSitePatterns PS01242 Zinc finger FPG-type signature. 250 274 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 THSYN_RS02780 1fa52fa7687bc26442bfa86748385f60 275 Gene3D G3DSA:1.10.8.50 136 275 2.3E-46 T 29-03-2018 THSYN_RS02780 1fa52fa7687bc26442bfa86748385f60 275 SUPERFAMILY SSF46946 136 228 9.13E-27 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 THSYN_RS02780 1fa52fa7687bc26442bfa86748385f60 275 SUPERFAMILY SSF81624 2 140 8.24E-40 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 THSYN_RS02780 1fa52fa7687bc26442bfa86748385f60 275 SUPERFAMILY SSF57716 223 274 5.13E-16 T 29-03-2018 THSYN_RS02780 1fa52fa7687bc26442bfa86748385f60 275 Gene3D G3DSA:3.20.190.10 2 129 6.1E-36 T 29-03-2018 THSYN_RS02780 1fa52fa7687bc26442bfa86748385f60 275 SMART SM00898 2 116 2.9E-46 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 THSYN_RS02780 1fa52fa7687bc26442bfa86748385f60 275 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 274 8.0E-85 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 THSYN_RS02780 1fa52fa7687bc26442bfa86748385f60 275 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 275 42.581 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 THSYN_RS02780 1fa52fa7687bc26442bfa86748385f60 275 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 135 224 2.4E-21 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 THSYN_RS02780 1fa52fa7687bc26442bfa86748385f60 275 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 113 3.1E-29 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 THSYN_RS02780 1fa52fa7687bc26442bfa86748385f60 275 Pfam PF06827 Zinc finger found in FPG and IleRS 247 275 2.9E-10 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 THSYN_RS02780 1fa52fa7687bc26442bfa86748385f60 275 SMART SM01232 135 227 6.8E-44 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 THSYN_RS08515 873379f2c8555d15302a5bb9ae124ec0 472 Gene3D G3DSA:1.10.101.10 392 464 1.2E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS08515 873379f2c8555d15302a5bb9ae124ec0 472 Gene3D G3DSA:1.10.530.10 261 385 2.7E-31 T 29-03-2018 THSYN_RS08515 873379f2c8555d15302a5bb9ae124ec0 472 SUPERFAMILY SSF47090 390 454 3.14E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS08515 873379f2c8555d15302a5bb9ae124ec0 472 Gene3D G3DSA:1.10.8.350 153 255 6.8E-35 T 29-03-2018 THSYN_RS08515 873379f2c8555d15302a5bb9ae124ec0 472 SUPERFAMILY SSF53955 78 385 1.69E-96 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS08515 873379f2c8555d15302a5bb9ae124ec0 472 Pfam PF13406 Transglycosylase SLT domain 87 378 3.5E-102 T 29-03-2018 IPR031304 Transglycosylase SLT domain 2 THSYN_RS08515 873379f2c8555d15302a5bb9ae124ec0 472 Pfam PF01471 Putative peptidoglycan binding domain 399 447 4.1E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS08515 873379f2c8555d15302a5bb9ae124ec0 472 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 86 381 1.3E-104 T 29-03-2018 IPR011970 Lytic murein transglycosylase THSYN_RS17445 752809fb96230c4b3fd98162cd3737fe 159 Pfam PF13686 DsrE/DsrF/DrsH-like family 3 157 6.9E-53 T 29-03-2018 IPR032836 DsrE2-like family THSYN_RS17445 752809fb96230c4b3fd98162cd3737fe 159 Gene3D G3DSA:3.40.1260.10 1 159 2.4E-53 T 29-03-2018 THSYN_RS17445 752809fb96230c4b3fd98162cd3737fe 159 SUPERFAMILY SSF75169 4 50 4.27E-20 T 29-03-2018 IPR027396 DsrEFH-like THSYN_RS17445 752809fb96230c4b3fd98162cd3737fe 159 SUPERFAMILY SSF75169 101 157 4.27E-20 T 29-03-2018 IPR027396 DsrEFH-like THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 Gene3D G3DSA:3.30.70.1430 63 164 5.3E-24 T 29-03-2018 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 SUPERFAMILY SSF82866 334 529 1.57E-36 T 29-03-2018 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 SUPERFAMILY SSF82866 865 917 3.27E-38 T 29-03-2018 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 SUPERFAMILY SSF82866 956 1103 3.27E-38 T 29-03-2018 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 PRINTS PR00702 Acriflavin resistance protein family signature 33 57 6.5E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 PRINTS PR00702 Acriflavin resistance protein family signature 481 504 6.5E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 PRINTS PR00702 Acriflavin resistance protein family signature 61 79 6.5E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 PRINTS PR00702 Acriflavin resistance protein family signature 506 529 6.5E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 PRINTS PR00702 Acriflavin resistance protein family signature 399 420 6.5E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 PRINTS PR00702 Acriflavin resistance protein family signature 427 451 6.5E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 PRINTS PR00702 Acriflavin resistance protein family signature 372 395 6.5E-31 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 Pfam PF00873 AcrB/AcrD/AcrF family 29 878 6.2E-113 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 Pfam PF00873 AcrB/AcrD/AcrF family 939 1103 2.6E-23 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 SUPERFAMILY SSF82714 772 860 2.22E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 Gene3D G3DSA:1.20.1640.10 308 531 2.1E-33 T 29-03-2018 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 Gene3D G3DSA:3.30.2090.10 210 298 4.6E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 SUPERFAMILY SSF82714 213 295 9.02E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 Gene3D G3DSA:3.30.2090.10 771 862 7.6E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 SUPERFAMILY SSF82693 63 156 3.49E-22 T 29-03-2018 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 SUPERFAMILY SSF82693 604 699 2.67E-7 T 29-03-2018 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 Gene3D G3DSA:3.30.70.1430 606 718 1.4E-15 T 29-03-2018 THSYN_RS13955 5143a70669890ec2f89957cac0e47d61 1414 Gene3D G3DSA:1.20.1640.10 873 1110 1.4E-26 T 29-03-2018 THSYN_RS18365 2c5427f2fb7797426fb16c0554f18fdf 512 Gene3D G3DSA:3.40.50.1820 226 512 2.0E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS18365 2c5427f2fb7797426fb16c0554f18fdf 512 SUPERFAMILY SSF53474 234 482 2.54E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS18365 2c5427f2fb7797426fb16c0554f18fdf 512 Pfam PF12697 Alpha/beta hydrolase family 240 489 1.3E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS29930 446a438161c418a2d6d6d667c0971a04 252 SMART SM00945 14 141 0.0015 T 29-03-2018 IPR016103 ProQ/FinO domain THSYN_RS29930 446a438161c418a2d6d6d667c0971a04 252 Gene3D G3DSA:1.10.1710.10 14 138 1.5E-19 T 29-03-2018 IPR016103 ProQ/FinO domain THSYN_RS29930 446a438161c418a2d6d6d667c0971a04 252 Pfam PF04352 ProQ/FINO family 23 125 1.5E-15 T 29-03-2018 IPR016103 ProQ/FinO domain THSYN_RS29930 446a438161c418a2d6d6d667c0971a04 252 SUPERFAMILY SSF48657 23 124 2.09E-16 T 29-03-2018 IPR016103 ProQ/FinO domain THSYN_RS32160 81561d7e3e61e05b65d2b854f72f8fec 141 SUPERFAMILY SSF159664 10 138 1.44E-35 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 THSYN_RS32160 81561d7e3e61e05b65d2b854f72f8fec 141 Pfam PF01890 Cobalamin synthesis G C-terminus 12 136 3.8E-33 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 THSYN_RS32160 81561d7e3e61e05b65d2b854f72f8fec 141 Gene3D G3DSA:3.30.420.180 4 140 2.1E-38 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 SUPERFAMILY SSF55008 2 67 1.31E-17 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 72 132 7.6E-9 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 6 65 7.9E-10 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 509 515 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 277 783 1.0E-85 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 SUPERFAMILY SSF81653 307 405 1.44E-26 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 238 814 2.4E-183 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 736 761 3.0E-6 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 705 721 3.0E-6 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 38 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 Gene3D G3DSA:3.30.70.100 69 135 9.4E-20 T 29-03-2018 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 Gene3D G3DSA:3.30.70.100 1 68 3.0E-19 T 29-03-2018 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 SUPERFAMILY SSF55008 70 135 1.83E-18 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 ProSitePatterns PS01047 Heavy-metal-associated domain. 75 104 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 219 815 2.3E-175 T 29-03-2018 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 Pfam PF00122 E1-E2 ATPase 306 485 3.9E-52 T 29-03-2018 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 Gene3D G3DSA:1.20.1110.10 661 813 1.1E-35 T 29-03-2018 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 SUPERFAMILY SSF56784 563 812 1.27E-54 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 SUPERFAMILY SSF56784 506 525 1.27E-54 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 521 3.3E-25 T 29-03-2018 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 355 369 3.3E-25 T 29-03-2018 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 630 641 3.3E-25 T 29-03-2018 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 705 724 3.3E-25 T 29-03-2018 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 652 662 3.3E-25 T 29-03-2018 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 728 740 3.3E-25 T 29-03-2018 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 SUPERFAMILY SSF81665 406 501 3.4E-15 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 SUPERFAMILY SSF81665 271 309 3.4E-15 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 SUPERFAMILY SSF81665 754 791 3.4E-15 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 Gene3D G3DSA:2.70.150.10 144 406 2.1E-37 T 29-03-2018 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 Gene3D G3DSA:3.40.1110.10 514 660 6.7E-40 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 Pfam PF00702 haloacid dehalogenase-like hydrolase 505 718 3.7E-41 T 29-03-2018 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 Pfam PF00403 Heavy-metal-associated domain 7 65 1.5E-15 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THSYN_RS18015 8b0cca79b1db3d7455817702ca48bd97 819 Pfam PF00403 Heavy-metal-associated domain 73 132 2.6E-13 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THSYN_RS16450 9ee9fc6a47f0e194d7352e635f138f43 562 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 82 220 3.0E-13 T 29-03-2018 THSYN_RS01775 d7602debf50a56110984807b3a670e35 77 Pfam PF04255 Protein of unknown function (DUF433) 8 63 1.6E-18 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS01775 d7602debf50a56110984807b3a670e35 77 SUPERFAMILY SSF46689 3 68 1.77E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS01775 d7602debf50a56110984807b3a670e35 77 Gene3D G3DSA:1.10.10.10 8 71 1.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS27140 85402f603465f3120df07a6c14b81f3f 310 SUPERFAMILY SSF52768 1 308 2.4E-102 T 29-03-2018 THSYN_RS27140 85402f603465f3120df07a6c14b81f3f 310 PRINTS PR01270 Histone deacetylase superfamily signature 236 246 1.6E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THSYN_RS27140 85402f603465f3120df07a6c14b81f3f 310 PRINTS PR01270 Histone deacetylase superfamily signature 124 147 1.6E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THSYN_RS27140 85402f603465f3120df07a6c14b81f3f 310 PRINTS PR01270 Histone deacetylase superfamily signature 158 173 1.6E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THSYN_RS27140 85402f603465f3120df07a6c14b81f3f 310 Gene3D G3DSA:3.40.800.20 1 310 2.0E-109 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THSYN_RS27140 85402f603465f3120df07a6c14b81f3f 310 Pfam PF00850 Histone deacetylase domain 20 305 1.3E-82 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THSYN_RS27420 e12e1e7ac9966a9c1028eea5dbb9ee56 357 Gene3D G3DSA:3.40.50.10140 16 262 9.6E-20 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS27420 e12e1e7ac9966a9c1028eea5dbb9ee56 357 Pfam PF03958 Bacterial type II/III secretion system short domain 293 355 1.1E-8 T 29-03-2018 IPR005644 NolW-like THSYN_RS27420 e12e1e7ac9966a9c1028eea5dbb9ee56 357 SMART SM00965 218 266 2.9E-8 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THSYN_RS27420 e12e1e7ac9966a9c1028eea5dbb9ee56 357 SUPERFAMILY SSF52200 14 137 2.75E-19 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS27420 e12e1e7ac9966a9c1028eea5dbb9ee56 357 Pfam PF13676 TIR domain 22 123 2.9E-16 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS27420 e12e1e7ac9966a9c1028eea5dbb9ee56 357 Pfam PF07660 Secretin and TonB N terminus short domain 219 265 5.2E-10 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THSYN_RS26705 82797e2b4216b2bbe5ad5a1c3c5bebad 478 Gene3D G3DSA:1.10.10.10 309 449 3.3E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26705 82797e2b4216b2bbe5ad5a1c3c5bebad 478 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 41 294 1.6E-43 T 29-03-2018 IPR017039 Virulence factor BrkB THSYN_RS26705 82797e2b4216b2bbe5ad5a1c3c5bebad 478 SUPERFAMILY SSF46785 335 437 1.63E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26705 82797e2b4216b2bbe5ad5a1c3c5bebad 478 Pfam PF03631 Virulence factor BrkB 50 298 1.8E-50 T 29-03-2018 IPR017039 Virulence factor BrkB THSYN_RS02300 f9eab759eca9411ef6c454336eda734d 674 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 8 673 8.1E-269 T 29-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 THSYN_RS02300 f9eab759eca9411ef6c454336eda734d 674 Pfam PF03030 Inorganic H+ pyrophosphatase 15 669 1.6E-269 T 29-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 THSYN_RS02300 f9eab759eca9411ef6c454336eda734d 674 PIRSF PIRSF001265 1 674 3.3E-260 T 29-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 THSYN_RS02300 f9eab759eca9411ef6c454336eda734d 674 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 3 674 25.655 T 29-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 THSYN_RS30660 2a49f57683ed4e85008a5f18305482ec 279 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 4 170 9.9E-49 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 THSYN_RS30660 2a49f57683ed4e85008a5f18305482ec 279 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 177 275 2.0E-20 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal THSYN_RS30660 2a49f57683ed4e85008a5f18305482ec 279 SUPERFAMILY SSF55447 175 275 4.32E-21 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal THSYN_RS30660 2a49f57683ed4e85008a5f18305482ec 279 Gene3D G3DSA:3.30.390.50 173 278 1.4E-23 T 29-03-2018 THSYN_RS30660 2a49f57683ed4e85008a5f18305482ec 279 Gene3D G3DSA:3.30.465.10 54 170 2.1E-34 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THSYN_RS30660 2a49f57683ed4e85008a5f18305482ec 279 Gene3D G3DSA:3.30.43.10 3 53 5.3E-12 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THSYN_RS30660 2a49f57683ed4e85008a5f18305482ec 279 SUPERFAMILY SSF56176 4 169 3.16E-50 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THSYN_RS30660 2a49f57683ed4e85008a5f18305482ec 279 SMART SM01092 176 279 4.0E-24 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal THSYN_RS27605 accf81903e41aa4c2edb7452c2756554 287 Gene3D G3DSA:3.90.1570.10 17 169 2.2E-22 T 29-03-2018 THSYN_RS27605 accf81903e41aa4c2edb7452c2756554 287 Pfam PF05685 Putative restriction endonuclease 36 155 3.2E-17 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS27605 accf81903e41aa4c2edb7452c2756554 287 SUPERFAMILY SSF52980 7 167 5.31E-30 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS03310 fbb0e8d01034c6082acef424bb1f2cef 111 Pfam PF13476 AAA domain 28 66 1.2E-8 T 29-03-2018 THSYN_RS03310 fbb0e8d01034c6082acef424bb1f2cef 111 Gene3D G3DSA:3.40.50.300 25 105 3.1E-10 T 29-03-2018 THSYN_RS03310 fbb0e8d01034c6082acef424bb1f2cef 111 SUPERFAMILY SSF52540 25 74 3.08E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31375 2173fded37911017ef9ffa584bc3e5e0 116 PRINTS PR00673 Light harvesting protein A chain signature 29 40 3.6E-11 T 29-03-2018 IPR018332 Antenna complex, alpha subunit THSYN_RS31375 2173fded37911017ef9ffa584bc3e5e0 116 PRINTS PR00673 Light harvesting protein A chain signature 10 29 3.6E-11 T 29-03-2018 IPR018332 Antenna complex, alpha subunit THSYN_RS31375 2173fded37911017ef9ffa584bc3e5e0 116 PRINTS PR00673 Light harvesting protein A chain signature 3 10 3.6E-11 T 29-03-2018 IPR018332 Antenna complex, alpha subunit THSYN_RS31375 2173fded37911017ef9ffa584bc3e5e0 116 Gene3D G3DSA:4.10.220.20 1 48 7.2E-21 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31375 2173fded37911017ef9ffa584bc3e5e0 116 ProSitePatterns PS00968 Antenna complexes alpha subunits signature. 23 41 - T 29-03-2018 IPR002361 Antenna complex, alpha subunit conserved site GO:0016021|GO:0019684|GO:0019866|GO:0030077|GO:0045156 THSYN_RS31375 2173fded37911017ef9ffa584bc3e5e0 116 SUPERFAMILY SSF56918 1 47 6.02E-18 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31375 2173fded37911017ef9ffa584bc3e5e0 116 Pfam PF00556 Antenna complex alpha/beta subunit 2 41 9.6E-15 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS06710 597303ba0897214de2cd80b0fcb89db2 334 SMART SM00471 146 283 2.2E-9 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS06710 597303ba0897214de2cd80b0fcb89db2 334 Gene3D G3DSA:3.40.50.2300 2 119 2.9E-32 T 29-03-2018 THSYN_RS06710 597303ba0897214de2cd80b0fcb89db2 334 Pfam PF00072 Response regulator receiver domain 7 116 1.5E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS06710 597303ba0897214de2cd80b0fcb89db2 334 SMART SM00448 4 116 7.1E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS06710 597303ba0897214de2cd80b0fcb89db2 334 Pfam PF01966 HD domain 153 273 5.9E-20 T 29-03-2018 IPR006674 HD domain THSYN_RS06710 597303ba0897214de2cd80b0fcb89db2 334 SUPERFAMILY SSF109604 125 314 1.68E-40 T 29-03-2018 THSYN_RS06710 597303ba0897214de2cd80b0fcb89db2 334 SUPERFAMILY SSF52172 2 141 4.13E-36 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS06710 597303ba0897214de2cd80b0fcb89db2 334 Gene3D G3DSA:1.10.3210.10 120 324 3.0E-51 T 29-03-2018 THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 Pfam PF13426 PAS domain 526 628 2.0E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 Pfam PF00563 EAL domain 818 1052 1.1E-66 T 29-03-2018 IPR001633 EAL domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 Gene3D G3DSA:3.30.450.20 88 219 2.3E-20 T 29-03-2018 THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SMART SM00086 465 507 2.5E-4 T 29-03-2018 IPR001610 PAC motif THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SMART SM00086 174 215 8.7E-6 T 29-03-2018 IPR001610 PAC motif THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SMART SM00086 587 629 0.0011 T 29-03-2018 IPR001610 PAC motif THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 Gene3D G3DSA:3.30.70.270 641 809 7.4E-60 T 29-03-2018 THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 636 800 1.0E-43 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SUPERFAMILY SSF55781 236 389 3.1E-15 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SMART SM00065 236 387 2.8E-4 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SUPERFAMILY SSF55785 407 516 1.66E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 Gene3D G3DSA:3.30.450.20 389 513 9.8E-20 T 29-03-2018 THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 Pfam PF00989 PAS fold 103 212 5.5E-11 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 Gene3D G3DSA:3.30.450.40 220 388 2.5E-17 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SMART SM00267 629 801 5.2E-60 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SMART SM00091 102 168 2.8E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SMART SM00091 515 581 4.6E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 Gene3D G3DSA:3.40.50.10600 514 634 9.9E-28 T 29-03-2018 THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SMART SM00052 811 1057 1.1E-103 T 29-03-2018 IPR001633 EAL domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 Pfam PF08447 PAS fold 414 500 2.3E-10 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SUPERFAMILY SSF55785 524 626 8.2E-28 T 29-03-2018 IPR000014 PAS domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 Pfam PF00990 Diguanylate cyclase, GGDEF domain 640 796 2.8E-47 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 520 636 7.3E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 99 217 1.8E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SUPERFAMILY SSF55785 94 213 1.41E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 Pfam PF13185 GAF domain 235 373 9.8E-26 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SUPERFAMILY SSF141868 817 1064 3.92E-77 T 29-03-2018 IPR001633 EAL domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 Gene3D G3DSA:3.20.20.450 810 1067 4.1E-93 T 29-03-2018 IPR001633 EAL domain THSYN_RS12995 ae2e6bebf19a3069c4462bfdde969a2a 1070 SUPERFAMILY SSF55073 645 802 6.04E-48 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS22895 999561010c5621b01c0578768b165531 323 Gene3D G3DSA:3.40.50.150 59 151 9.5E-6 T 29-03-2018 THSYN_RS22895 999561010c5621b01c0578768b165531 323 Pfam PF13489 Methyltransferase domain 109 255 5.7E-21 T 29-03-2018 THSYN_RS22895 999561010c5621b01c0578768b165531 323 Gene3D G3DSA:3.40.50.150 156 303 2.8E-13 T 29-03-2018 THSYN_RS22895 999561010c5621b01c0578768b165531 323 SUPERFAMILY SSF53335 111 264 1.66E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS25105 0a5752ba4dc4f8f1d0b4174f00b34d6e 341 Gene3D G3DSA:3.40.50.2000 115 310 2.5E-10 T 29-03-2018 THSYN_RS25105 0a5752ba4dc4f8f1d0b4174f00b34d6e 341 SUPERFAMILY SSF53756 40 334 5.9E-13 T 29-03-2018 THSYN_RS32380 4567b9116ac1535f499843113495044f 363 Gene3D G3DSA:3.30.1330.20 214 323 2.9E-33 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 THSYN_RS32380 4567b9116ac1535f499843113495044f 363 SMART SM00864 13 205 1.2E-80 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS32380 4567b9116ac1535f499843113495044f 363 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 363 30.889 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 THSYN_RS32380 4567b9116ac1535f499843113495044f 363 Pfam PF12327 FtsZ family, C-terminal domain 221 316 1.3E-27 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal THSYN_RS32380 4567b9116ac1535f499843113495044f 363 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.9E-29 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS32380 4567b9116ac1535f499843113495044f 363 PRINTS PR00423 Cell division protein FtsZ signature 211 232 1.9E-29 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS32380 4567b9116ac1535f499843113495044f 363 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.9E-29 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS32380 4567b9116ac1535f499843113495044f 363 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 15 168 1.9E-33 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS32380 4567b9116ac1535f499843113495044f 363 Gene3D G3DSA:3.40.50.1440 13 213 1.7E-31 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS32380 4567b9116ac1535f499843113495044f 363 SMART SM00865 206 324 1.9E-34 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 THSYN_RS32380 4567b9116ac1535f499843113495044f 363 SUPERFAMILY SSF55307 206 320 1.33E-32 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 THSYN_RS32380 4567b9116ac1535f499843113495044f 363 SUPERFAMILY SSF52490 15 200 1.31E-58 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS32380 4567b9116ac1535f499843113495044f 363 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 9 323 2.6E-101 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 THSYN_RS00945 7edc1915cbae5cd449182e452ad21cd9 264 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 11 123 2.2E-11 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 THSYN_RS00945 7edc1915cbae5cd449182e452ad21cd9 264 SUPERFAMILY SSF52402 9 128 2.12E-22 T 29-03-2018 THSYN_RS00945 7edc1915cbae5cd449182e452ad21cd9 264 Gene3D G3DSA:3.40.50.620 1 240 4.0E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS14515 85ef88f7814d9befcb2cf390a518d7a9 359 Gene3D G3DSA:3.60.21.10 124 325 1.5E-21 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS14515 85ef88f7814d9befcb2cf390a518d7a9 359 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 126 284 1.5E-10 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 THSYN_RS14515 85ef88f7814d9befcb2cf390a518d7a9 359 SUPERFAMILY SSF56300 122 343 8.58E-31 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS25195 48c7cc81f6c2ed7af65c5602e79c36b2 208 Gene3D G3DSA:3.20.20.190 1 208 1.9E-5 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 THSYN_RS25195 48c7cc81f6c2ed7af65c5602e79c36b2 208 SUPERFAMILY SSF51695 1 206 4.19E-13 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 THSYN_RS23430 caf450a74d022144f96daea646a8e357 214 Hamap MF_00013 Octanoyltransferase [lipB]. 7 213 37.033 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THSYN_RS23430 caf450a74d022144f96daea646a8e357 214 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 74 89 - T 29-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 THSYN_RS23430 caf450a74d022144f96daea646a8e357 214 PIRSF PIRSF016262 5 208 1.2E-55 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THSYN_RS23430 caf450a74d022144f96daea646a8e357 214 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 30 190 1.1E-59 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THSYN_RS23430 caf450a74d022144f96daea646a8e357 214 Gene3D G3DSA:3.30.930.10 6 207 2.1E-59 T 29-03-2018 THSYN_RS23430 caf450a74d022144f96daea646a8e357 214 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 78 131 6.0E-12 T 29-03-2018 THSYN_RS23430 caf450a74d022144f96daea646a8e357 214 Pfam PF03099 Biotin/lipoate A/B protein ligase family 60 162 3.2E-9 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 THSYN_RS23430 caf450a74d022144f96daea646a8e357 214 SUPERFAMILY SSF55681 10 194 1.41E-66 T 29-03-2018 THSYN_RS10230 a08c19c329f3b011b8365461f0e0356a 140 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 4 127 4.0E-32 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 THSYN_RS10230 a08c19c329f3b011b8365461f0e0356a 140 ProSitePatterns PS00550 Hemerythrin family signature. 57 80 - T 29-03-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 THSYN_RS10230 a08c19c329f3b011b8365461f0e0356a 140 SUPERFAMILY SSF47188 2 127 1.06E-27 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 THSYN_RS10230 a08c19c329f3b011b8365461f0e0356a 140 Gene3D G3DSA:1.20.120.50 2 130 8.9E-34 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 THSYN_RS10230 a08c19c329f3b011b8365461f0e0356a 140 Pfam PF01814 Hemerythrin HHE cation binding domain 13 123 4.1E-13 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THSYN_RS21320 294b739f63907422149d7196f95885ee 514 TIGRFAM TIGR02602 8TM_EpsH: exosortase 41 277 6.8E-76 T 29-03-2018 IPR013426 Exosortase, EpsH THSYN_RS21320 294b739f63907422149d7196f95885ee 514 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 184 277 3.3E-20 T 29-03-2018 IPR026392 Exosortase/Archaeosortase domain THSYN_RS21320 294b739f63907422149d7196f95885ee 514 Pfam PF11984 Protein of unknown function (DUF3485) 305 504 8.8E-37 T 29-03-2018 IPR014263 Methanolan biosynthesis EpsI THSYN_RS21320 294b739f63907422149d7196f95885ee 514 TIGRFAM TIGR03109 exosortase_1: exosortase A 15 279 4.3E-95 T 29-03-2018 IPR017540 Exosortase 1 THSYN_RS21320 294b739f63907422149d7196f95885ee 514 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 27 276 2.6E-60 T 29-03-2018 IPR019127 Exosortase EpsH-related THSYN_RS21320 294b739f63907422149d7196f95885ee 514 TIGRFAM TIGR02914 EpsI_fam: EpsI family protein 333 504 1.0E-34 T 29-03-2018 IPR014263 Methanolan biosynthesis EpsI THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 PIRSF PIRSF500210 1 337 1.1E-128 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 276 288 - T 29-03-2018 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 PIRSF PIRSF000904 1 337 7.5E-126 T 29-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 SUPERFAMILY SSF56655 2 334 2.33E-118 T 29-03-2018 THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 6 195 3.0E-67 T 29-03-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 Gene3D G3DSA:3.40.190.80 201 337 9.9E-52 T 29-03-2018 THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 5 336 46.965 T 29-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 310 335 9.1E-74 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 30 57 9.1E-74 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 67 93 9.1E-74 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 206 233 9.1E-74 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 149 172 9.1E-74 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 180 203 9.1E-74 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THSYN_RS25810 91d602b3923185499abff4264e41b1e8 337 Gene3D G3DSA:3.30.540.10 9 200 4.2E-64 T 29-03-2018 THSYN_RS26945 3fa3c75b7329fc706ef32e07eeb2e708 193 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 2 190 5.9E-80 T 29-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 THSYN_RS26945 3fa3c75b7329fc706ef32e07eeb2e708 193 PIRSF PIRSF006102 1 193 2.7E-55 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 THSYN_RS26945 3fa3c75b7329fc706ef32e07eeb2e708 193 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 190 5.7E-57 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 THSYN_RS26945 3fa3c75b7329fc706ef32e07eeb2e708 193 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 2 191 24.825 T 29-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 THSYN_RS17915 ec8bf0c8cb2b7e43c66fa60244485788 214 Gene3D G3DSA:3.90.226.10 16 208 6.4E-43 T 29-03-2018 THSYN_RS17915 ec8bf0c8cb2b7e43c66fa60244485788 214 PRINTS PR00127 Clp protease catalytic subunit P signature 33 48 1.1E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THSYN_RS17915 ec8bf0c8cb2b7e43c66fa60244485788 214 PRINTS PR00127 Clp protease catalytic subunit P signature 104 121 1.1E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THSYN_RS17915 ec8bf0c8cb2b7e43c66fa60244485788 214 PRINTS PR00127 Clp protease catalytic subunit P signature 125 144 1.1E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THSYN_RS17915 ec8bf0c8cb2b7e43c66fa60244485788 214 PRINTS PR00127 Clp protease catalytic subunit P signature 182 201 1.1E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THSYN_RS17915 ec8bf0c8cb2b7e43c66fa60244485788 214 PRINTS PR00127 Clp protease catalytic subunit P signature 73 93 1.1E-52 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THSYN_RS17915 ec8bf0c8cb2b7e43c66fa60244485788 214 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 126 139 - T 29-03-2018 IPR033135 ClpP, histidine active site THSYN_RS17915 ec8bf0c8cb2b7e43c66fa60244485788 214 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 17 207 43.597 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THSYN_RS17915 ec8bf0c8cb2b7e43c66fa60244485788 214 Pfam PF00574 Clp protease 27 206 1.7E-83 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA THSYN_RS17915 ec8bf0c8cb2b7e43c66fa60244485788 214 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 104 115 - T 29-03-2018 IPR018215 ClpP, Ser active site THSYN_RS17915 ec8bf0c8cb2b7e43c66fa60244485788 214 SUPERFAMILY SSF52096 25 207 6.63E-72 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS17915 ec8bf0c8cb2b7e43c66fa60244485788 214 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 16 205 2.4E-101 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THSYN_RS31470 e86d6ec3f8984aafefb447dc30848742 72 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 1 72 20.249 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 THSYN_RS31470 e86d6ec3f8984aafefb447dc30848742 72 Pfam PF00741 Gas vesicle protein 12 50 2.2E-16 T 29-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 THSYN_RS31470 e86d6ec3f8984aafefb447dc30848742 72 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 46 59 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 THSYN_RS31470 e86d6ec3f8984aafefb447dc30848742 72 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 13 27 - T 29-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 THSYN_RS31370 c8aad1ff546b73f8c07edb483efc1330 48 Gene3D G3DSA:1.20.5.250 1 48 8.7E-24 T 29-03-2018 THSYN_RS31370 c8aad1ff546b73f8c07edb483efc1330 48 SUPERFAMILY SSF56918 2 48 1.31E-17 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31370 c8aad1ff546b73f8c07edb483efc1330 48 Pfam PF00556 Antenna complex alpha/beta subunit 14 48 4.5E-12 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31370 c8aad1ff546b73f8c07edb483efc1330 48 PIRSF PIRSF002900 1 48 2.4E-23 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31370 c8aad1ff546b73f8c07edb483efc1330 48 PRINTS PR00674 Light harvesting protein B chain signature 10 30 4.9E-12 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31370 c8aad1ff546b73f8c07edb483efc1330 48 PRINTS PR00674 Light harvesting protein B chain signature 30 47 4.9E-12 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31370 c8aad1ff546b73f8c07edb483efc1330 48 ProSitePatterns PS00969 Antenna complexes beta subunits signature. 15 46 - T 29-03-2018 IPR023623 Antenna complex, beta subunit, conserved site THSYN_RS00205 3de6a5d512177d29801c5f96937ce20a 192 Pfam PF01871 AMMECR1 19 189 6.2E-43 T 29-03-2018 IPR002733 AMMECR1 domain THSYN_RS00205 3de6a5d512177d29801c5f96937ce20a 192 SUPERFAMILY SSF143447 4 191 1.44E-53 T 29-03-2018 IPR002733 AMMECR1 domain THSYN_RS00205 3de6a5d512177d29801c5f96937ce20a 192 Gene3D G3DSA:3.30.700.20 7 130 5.9E-31 T 29-03-2018 IPR027485 AMMECR1, N-terminal THSYN_RS00205 3de6a5d512177d29801c5f96937ce20a 192 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 16 190 1.1E-58 T 29-03-2018 IPR027623 AmmeMemoRadiSam system protein A THSYN_RS00205 3de6a5d512177d29801c5f96937ce20a 192 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 41 190 1.8E-30 T 29-03-2018 IPR023473 AMMECR1 THSYN_RS00205 3de6a5d512177d29801c5f96937ce20a 192 Gene3D G3DSA:3.30.1490.150 131 185 3.1E-16 T 29-03-2018 THSYN_RS22290 f5ebc2cccc2905cda21b36ce30bde2dc 225 Gene3D G3DSA:3.40.50.1000 83 225 8.9E-36 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS22290 f5ebc2cccc2905cda21b36ce30bde2dc 225 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 4 221 34.051 T 29-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 THSYN_RS22290 f5ebc2cccc2905cda21b36ce30bde2dc 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 126 190 1.1E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS22290 f5ebc2cccc2905cda21b36ce30bde2dc 225 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 106 185 1.8E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS22290 f5ebc2cccc2905cda21b36ce30bde2dc 225 SUPERFAMILY SSF56784 4 220 1.31E-57 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS22290 f5ebc2cccc2905cda21b36ce30bde2dc 225 Gene3D G3DSA:1.10.150.240 19 82 1.1E-19 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 THSYN_RS22290 f5ebc2cccc2905cda21b36ce30bde2dc 225 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 7 219 4.2E-65 T 29-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 THSYN_RS22290 f5ebc2cccc2905cda21b36ce30bde2dc 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 189 1.3E-30 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS21300 8b104aa7172ff0e49169062f47bbbd3b 577 SUPERFAMILY SSF52402 430 511 2.17E-10 T 29-03-2018 THSYN_RS21300 8b104aa7172ff0e49169062f47bbbd3b 577 SUPERFAMILY SSF52402 206 358 2.17E-10 T 29-03-2018 THSYN_RS21300 8b104aa7172ff0e49169062f47bbbd3b 577 Gene3D G3DSA:3.40.50.620 201 518 1.1E-9 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS29690 c574894eec246db01fc72c43ffa49403 319 Pfam PF06250 Protein of unknown function (DUF1016) 14 264 2.8E-86 T 29-03-2018 IPR009362 Protein of unknown function DUF1016 THSYN_RS18615 d2979c8d9e72eb210952afba663fb3d6 463 Pfam PF01739 CheR methyltransferase, SAM binding domain 73 249 2.8E-37 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal THSYN_RS18615 d2979c8d9e72eb210952afba663fb3d6 463 Gene3D G3DSA:1.25.40.10 320 458 3.3E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18615 d2979c8d9e72eb210952afba663fb3d6 463 SMART SM00138 8 267 5.2E-37 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS18615 d2979c8d9e72eb210952afba663fb3d6 463 SUPERFAMILY SSF53335 73 252 2.61E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS18615 d2979c8d9e72eb210952afba663fb3d6 463 SUPERFAMILY SSF48452 343 452 6.13E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18615 d2979c8d9e72eb210952afba663fb3d6 463 PRINTS PR00996 Glutamate methyltransferase family signature 227 250 8.4E-24 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS18615 d2979c8d9e72eb210952afba663fb3d6 463 PRINTS PR00996 Glutamate methyltransferase family signature 66 78 8.4E-24 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS18615 d2979c8d9e72eb210952afba663fb3d6 463 PRINTS PR00996 Glutamate methyltransferase family signature 138 154 8.4E-24 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS18615 d2979c8d9e72eb210952afba663fb3d6 463 PRINTS PR00996 Glutamate methyltransferase family signature 208 222 8.4E-24 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS18615 d2979c8d9e72eb210952afba663fb3d6 463 PRINTS PR00996 Glutamate methyltransferase family signature 105 125 8.4E-24 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THSYN_RS18615 d2979c8d9e72eb210952afba663fb3d6 463 Gene3D G3DSA:3.40.50.150 72 264 2.7E-37 T 29-03-2018 THSYN_RS28260 6a652ca5e2b3e50a2df42e46d25d2aa0 334 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 4 325 52.351 T 29-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 THSYN_RS28260 6a652ca5e2b3e50a2df42e46d25d2aa0 334 Gene3D G3DSA:3.20.20.70 6 246 4.4E-46 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS28260 6a652ca5e2b3e50a2df42e46d25d2aa0 334 PIRSF PIRSF006621 2 328 8.2E-72 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THSYN_RS28260 6a652ca5e2b3e50a2df42e46d25d2aa0 334 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 91 109 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 THSYN_RS28260 6a652ca5e2b3e50a2df42e46d25d2aa0 334 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 8 320 5.9E-136 T 29-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 THSYN_RS28260 6a652ca5e2b3e50a2df42e46d25d2aa0 334 Pfam PF01207 Dihydrouridine synthase (Dus) 12 311 6.7E-82 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THSYN_RS28260 6a652ca5e2b3e50a2df42e46d25d2aa0 334 SUPERFAMILY SSF51395 9 314 1.71E-75 T 29-03-2018 THSYN_RS02290 b7b454c19e3a6c0f3b033648ffcd899e 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 1.2E-16 T 29-03-2018 THSYN_RS02290 b7b454c19e3a6c0f3b033648ffcd899e 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 1.2E-16 T 29-03-2018 THSYN_RS02290 b7b454c19e3a6c0f3b033648ffcd899e 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 1.2E-16 T 29-03-2018 THSYN_RS02290 b7b454c19e3a6c0f3b033648ffcd899e 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.2E-16 T 29-03-2018 THSYN_RS02290 b7b454c19e3a6c0f3b033648ffcd899e 403 Gene3D G3DSA:3.50.50.60 4 365 1.6E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS02290 b7b454c19e3a6c0f3b033648ffcd899e 403 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 7 392 1.4E-136 T 29-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 THSYN_RS02290 b7b454c19e3a6c0f3b033648ffcd899e 403 Pfam PF01494 FAD binding domain 6 332 2.0E-25 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 THSYN_RS02290 b7b454c19e3a6c0f3b033648ffcd899e 403 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 296 309 - T 29-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 THSYN_RS02290 b7b454c19e3a6c0f3b033648ffcd899e 403 SUPERFAMILY SSF51905 6 179 3.74E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS02290 b7b454c19e3a6c0f3b033648ffcd899e 403 SUPERFAMILY SSF51905 278 394 3.74E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 SUPERFAMILY SSF52540 353 557 1.08E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 PRINTS PR00819 CbxX/CfqX superfamily signature 801 813 1.6E-30 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 PRINTS PR00819 CbxX/CfqX superfamily signature 585 599 1.6E-30 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 PRINTS PR00819 CbxX/CfqX superfamily signature 673 692 1.6E-30 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 PRINTS PR00819 CbxX/CfqX superfamily signature 724 741 1.6E-30 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 PRINTS PR00819 CbxX/CfqX superfamily signature 703 715 1.6E-30 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 PRINTS PR00819 CbxX/CfqX superfamily signature 659 673 1.6E-30 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 PRINTS PR00819 CbxX/CfqX superfamily signature 741 760 1.6E-30 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 SMART SM00382 618 756 7.6E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 SMART SM00382 353 468 9.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 SUPERFAMILY SSF52540 585 791 1.23E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 Gene3D G3DSA:3.40.50.300 289 483 1.9E-21 T 29-03-2018 THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 Gene3D G3DSA:3.40.50.300 573 753 4.0E-19 T 29-03-2018 THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 358 458 3.8E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS06215 4a966206ac848017cdff7949761171b9 842 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 623 735 1.0E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS07065 30541fdfbf4efe7a9df226f2daa8ce14 501 SUPERFAMILY SSF53649 36 459 9.89E-133 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS07065 30541fdfbf4efe7a9df226f2daa8ce14 501 ProSitePatterns PS00149 Sulfatases signature 2. 129 139 - T 29-03-2018 IPR024607 Sulfatase, conserved site THSYN_RS07065 30541fdfbf4efe7a9df226f2daa8ce14 501 ProSitePatterns PS00523 Sulfatases signature 1. 81 93 - T 29-03-2018 IPR024607 Sulfatase, conserved site THSYN_RS07065 30541fdfbf4efe7a9df226f2daa8ce14 501 Gene3D G3DSA:3.30.1120.10 390 469 1.7E-16 T 29-03-2018 THSYN_RS07065 30541fdfbf4efe7a9df226f2daa8ce14 501 Pfam PF00884 Sulfatase 37 365 6.7E-82 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THSYN_RS07065 30541fdfbf4efe7a9df226f2daa8ce14 501 Gene3D G3DSA:3.40.720.10 33 239 6.3E-65 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS07065 30541fdfbf4efe7a9df226f2daa8ce14 501 Gene3D G3DSA:3.40.720.10 240 389 3.3E-33 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS13815 59996acf3d0c445fd6da2913f888a23c 658 Pfam PF13091 PLD-like domain 479 624 6.6E-17 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THSYN_RS13815 59996acf3d0c445fd6da2913f888a23c 658 Pfam PF13091 PLD-like domain 272 418 1.2E-7 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THSYN_RS13815 59996acf3d0c445fd6da2913f888a23c 658 SUPERFAMILY SSF56024 474 636 9.42E-26 T 29-03-2018 THSYN_RS13815 59996acf3d0c445fd6da2913f888a23c 658 Gene3D G3DSA:3.30.870.10 245 432 2.1E-20 T 29-03-2018 THSYN_RS13815 59996acf3d0c445fd6da2913f888a23c 658 SUPERFAMILY SSF56024 250 426 1.32E-27 T 29-03-2018 THSYN_RS13815 59996acf3d0c445fd6da2913f888a23c 658 Gene3D G3DSA:3.30.870.10 468 638 2.2E-24 T 29-03-2018 THSYN_RS07055 043625a8deb0b039a7540ea649fc47ff 324 Pfam PF13557 Putative MetA-pathway of phenol degradation 81 320 7.2E-48 T 29-03-2018 IPR025737 MetA-pathway of phenol degradation, putative THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 Gene3D G3DSA:3.30.450.20 52 172 2.1E-27 T 29-03-2018 THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 SMART SM00387 433 546 9.8E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 55 175 1.4E-20 T 29-03-2018 IPR000014 PAS domain THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 Gene3D G3DSA:3.30.450.20 173 341 4.2E-15 T 29-03-2018 THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 502 1.8E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 524 1.8E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 488 1.8E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 SUPERFAMILY SSF55785 60 166 1.59E-24 T 29-03-2018 IPR000014 PAS domain THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 TIGRFAM TIGR02938 nifL_nitrog: nitrogen fixation negative regulator NifL 51 542 1.9E-158 T 29-03-2018 IPR014285 Nitrogen fixation negative regulator NifL GO:0004871|GO:0007165|GO:0009399|GO:0050660 THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 SUPERFAMILY SSF55785 165 273 9.42E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 Gene3D G3DSA:3.30.565.10 394 549 2.7E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 Pfam PF08448 PAS fold 186 277 1.6E-5 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 Pfam PF00989 PAS fold 58 165 3.6E-19 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 SUPERFAMILY SSF55874 394 542 1.44E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 SMART SM00091 180 246 0.03 T 29-03-2018 IPR000014 PAS domain THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 SMART SM00091 54 120 5.1E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS24765 682b5e896932e3c9f5dc8d44eae39ee7 549 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 434 542 1.1E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS06820 04c48ab0d1c67f7bbec3bdce284927f1 239 SUPERFAMILY SSF53448 6 208 1.28E-50 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS06820 04c48ab0d1c67f7bbec3bdce284927f1 239 Gene3D G3DSA:3.90.550.10 3 237 1.3E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS06820 04c48ab0d1c67f7bbec3bdce284927f1 239 Pfam PF00535 Glycosyl transferase family 2 8 110 7.6E-30 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS09965 fedf895e880cb7c5efe467b59cb8b90f 995 Pfam PF09369 Domain of unknown function (DUF1998) 883 967 2.4E-5 T 29-03-2018 IPR018973 DEAD/DEAH-box helicase, putative THSYN_RS09965 fedf895e880cb7c5efe467b59cb8b90f 995 Gene3D G3DSA:3.40.50.720 179 552 0.23 T 29-03-2018 THSYN_RS09965 fedf895e880cb7c5efe467b59cb8b90f 995 Gene3D G3DSA:3.40.50.720 614 813 0.019 T 29-03-2018 THSYN_RS16895 2affafaec626a253508b014df856b934 85 TIGRFAM TIGR02574 stabl_TIGR02574: putative addiction module component, TIGR02574 family 12 70 1.5E-8 T 29-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THSYN_RS16895 2affafaec626a253508b014df856b934 85 Pfam PF09720 Putative addiction module component 14 66 3.3E-18 T 29-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THSYN_RS30215 e61cc0cee05542af3bcef1c0e3b8e9ce 153 SUPERFAMILY SSF55729 7 141 5.32E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS30215 e61cc0cee05542af3bcef1c0e3b8e9ce 153 Pfam PF00583 Acetyltransferase (GNAT) family 10 141 1.4E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS30215 e61cc0cee05542af3bcef1c0e3b8e9ce 153 Gene3D G3DSA:3.40.630.30 3 142 2.1E-13 T 29-03-2018 THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 Gene3D G3DSA:3.30.565.10 1 230 1.9E-52 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 SUPERFAMILY SSF55874 8 217 4.06E-63 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 Hamap MF_00505 Chaperone protein HtpG [htpG]. 5 641 32.09 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 PRINTS PR00775 90kDa heat shock protein signature 8 28 3.4E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 PRINTS PR00775 90kDa heat shock protein signature 194 212 3.4E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 PRINTS PR00775 90kDa heat shock protein signature 176 193 3.4E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 PRINTS PR00775 90kDa heat shock protein signature 79 96 3.4E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 PRINTS PR00775 90kDa heat shock protein signature 124 146 3.4E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 PRINTS PR00775 90kDa heat shock protein signature 97 114 3.4E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 PRINTS PR00775 90kDa heat shock protein signature 29 51 3.4E-60 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 Pfam PF00183 Hsp90 protein 223 645 3.8E-130 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 SMART SM00387 30 188 3.4E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 PIRSF PIRSF002583 2 649 9.5E-215 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 187 2.3E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 SUPERFAMILY SSF54211 248 502 1.21E-97 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 28 37 - T 29-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 THSYN_RS06645 933ef914d82e8382cae78a9b636f36a5 653 SUPERFAMILY SSF110942 529 641 5.49E-35 T 29-03-2018 THSYN_RS13080 759ec7ec14a97b89a87401818b78a3ae 281 Gene3D G3DSA:1.10.10.580 196 266 8.3E-14 T 29-03-2018 THSYN_RS13080 759ec7ec14a97b89a87401818b78a3ae 281 Hamap MF_01805 Segregation and condensation protein A [scpA]. 38 268 22.387 T 29-03-2018 IPR003768 Segregation and condensation protein A THSYN_RS13080 759ec7ec14a97b89a87401818b78a3ae 281 Pfam PF02616 Segregation and condensation protein ScpA 55 265 4.3E-26 T 29-03-2018 IPR003768 Segregation and condensation protein A THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 SUPERFAMILY SSF117074 1544 1622 3.92E-5 T 29-03-2018 THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 SUPERFAMILY SSF117074 1391 1482 7.85E-17 T 29-03-2018 THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Gene3D G3DSA:2.60.40.290 632 744 2.8E-6 T 29-03-2018 THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Gene3D G3DSA:2.60.40.740 203 343 6.1E-7 T 29-03-2018 THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Gene3D G3DSA:2.60.40.740 891 1021 4.7E-4 T 29-03-2018 THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Gene3D G3DSA:2.60.40.740 759 890 6.7E-9 T 29-03-2018 THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Gene3D G3DSA:2.60.40.740 487 631 1.1E-9 T 29-03-2018 THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Gene3D G3DSA:2.60.40.10 1567 1622 1.3E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Gene3D G3DSA:2.60.40.10 1408 1566 1.5E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Pfam PF01345 Domain of unknown function DUF11 1158 1238 1.1E-8 T 29-03-2018 IPR001434 Domain of unknown function DUF11 THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1164 1204 5.8E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 62 102 2.9E-4 T 29-03-2018 IPR001434 Domain of unknown function DUF11 THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 493 531 1.0E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Gene3D G3DSA:2.60.40.10 1155 1280 2.7E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Gene3D G3DSA:2.60.40.10 51 200 1.6E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Gene3D G3DSA:2.60.40.10 346 486 1.5E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Gene3D G3DSA:2.60.40.10 1022 1153 1.7E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Gene3D G3DSA:2.60.40.10 1282 1407 3.5E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS08385 89609c253c1ce38ccf4f21f48fe82b34 1622 Pfam PF17210 SdrD B-like domain 1412 1483 3.0E-16 T 29-03-2018 IPR033764 SD-repeat containing protein, B domain THSYN_RS15745 d1dc649c3413efd799b2ff49d1d0a932 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 96.921 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 THSYN_RS15745 d1dc649c3413efd799b2ff49d1d0a932 198 Gene3D G3DSA:3.40.1360.10 77 170 2.4E-32 T 29-03-2018 THSYN_RS15745 d1dc649c3413efd799b2ff49d1d0a932 198 Pfam PF13662 Toprim domain 82 171 4.3E-21 T 29-03-2018 IPR006171 TOPRIM domain THSYN_RS15745 d1dc649c3413efd799b2ff49d1d0a932 198 Pfam PF02132 RecR protein 41 78 4.6E-13 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger THSYN_RS15745 d1dc649c3413efd799b2ff49d1d0a932 198 TIGRFAM TIGR00615 recR: recombination protein RecR 4 196 1.6E-71 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 THSYN_RS15745 d1dc649c3413efd799b2ff49d1d0a932 198 SUPERFAMILY SSF111304 4 198 1.44E-70 T 29-03-2018 IPR023627 Recombination protein RecR THSYN_RS15745 d1dc649c3413efd799b2ff49d1d0a932 198 SMART SM00493 80 165 0.001 T 29-03-2018 IPR006171 TOPRIM domain THSYN_RS15745 d1dc649c3413efd799b2ff49d1d0a932 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 29-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 THSYN_RS17225 b03d5beb22fdf54c22498d13f0eac91b 294 SMART SM00671 82 117 1.7E-9 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS17225 b03d5beb22fdf54c22498d13f0eac91b 294 SMART SM00671 46 81 1.4 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS17225 b03d5beb22fdf54c22498d13f0eac91b 294 Gene3D G3DSA:2.60.40.1180 25 138 6.6E-20 T 29-03-2018 THSYN_RS17225 b03d5beb22fdf54c22498d13f0eac91b 294 Pfam PF01464 Transglycosylase SLT domain 180 274 1.5E-28 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 THSYN_RS17225 b03d5beb22fdf54c22498d13f0eac91b 294 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 194 222 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 THSYN_RS17225 b03d5beb22fdf54c22498d13f0eac91b 294 Pfam PF08238 Sel1 repeat 54 81 0.035 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS17225 b03d5beb22fdf54c22498d13f0eac91b 294 Pfam PF08238 Sel1 repeat 84 117 1.3E-8 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS17225 b03d5beb22fdf54c22498d13f0eac91b 294 SUPERFAMILY SSF53955 168 290 6.19E-45 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS17225 b03d5beb22fdf54c22498d13f0eac91b 294 SUPERFAMILY SSF81901 34 125 4.97E-17 T 29-03-2018 THSYN_RS17225 b03d5beb22fdf54c22498d13f0eac91b 294 Gene3D G3DSA:1.10.530.10 158 292 7.7E-44 T 29-03-2018 THSYN_RS31460 96c0a8d19d23a9acb3bdd29e1ed242b5 69 Pfam PF04255 Protein of unknown function (DUF433) 6 54 2.6E-17 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS31460 96c0a8d19d23a9acb3bdd29e1ed242b5 69 SUPERFAMILY SSF46689 4 56 5.91E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS31460 96c0a8d19d23a9acb3bdd29e1ed242b5 69 Gene3D G3DSA:1.10.10.10 6 65 8.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 Gene3D G3DSA:1.25.40.10 49 100 6.2E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 SUPERFAMILY SSF53335 249 447 8.81E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 Gene3D G3DSA:1.20.58.280 6 48 0.033 T 29-03-2018 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 Gene3D G3DSA:1.25.40.10 167 200 1.5E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 Pfam PF13432 Tetratricopeptide repeat 94 153 3.4E-9 T 29-03-2018 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 Pfam PF13432 Tetratricopeptide repeat 31 86 1.2E-7 T 29-03-2018 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 Gene3D G3DSA:3.40.50.150 241 433 1.9E-21 T 29-03-2018 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 Gene3D G3DSA:1.25.40.10 101 139 2.9E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 SUPERFAMILY SSF48452 27 231 1.04E-36 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 Gene3D G3DSA:1.25.40.10 201 235 1.5E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 Gene3D G3DSA:1.25.40.10 140 166 3.9E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 SMART SM00028 53 86 1.4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 SMART SM00028 155 188 1.7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 SMART SM00028 19 52 36.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 SMART SM00028 189 222 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 SMART SM00028 87 120 0.067 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 SMART SM00028 121 154 1.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 Pfam PF13428 Tetratricopeptide repeat 194 231 9.4E-6 T 29-03-2018 THSYN_RS32685 d502fad9cacd156821b86e14b3472e85 450 Pfam PF13649 Methyltransferase domain 289 378 2.1E-12 T 29-03-2018 THSYN_RS23225 d4cde63f7af2c51c0a022f44225a0450 343 SUPERFAMILY SSF109998 50 224 1.26E-32 T 29-03-2018 IPR027304 Trigger factor/SurA domain THSYN_RS23225 d4cde63f7af2c51c0a022f44225a0450 343 Gene3D G3DSA:3.10.50.40 185 320 3.5E-48 T 29-03-2018 THSYN_RS23225 d4cde63f7af2c51c0a022f44225a0450 343 Pfam PF13624 SurA N-terminal domain 49 160 3.3E-12 T 29-03-2018 THSYN_RS23225 d4cde63f7af2c51c0a022f44225a0450 343 Pfam PF13616 PPIC-type PPIASE domain 187 295 1.2E-34 T 29-03-2018 THSYN_RS23225 d4cde63f7af2c51c0a022f44225a0450 343 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 234 254 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 THSYN_RS23225 d4cde63f7af2c51c0a022f44225a0450 343 Gene3D G3DSA:1.10.4030.10 43 170 8.1E-19 T 29-03-2018 THSYN_RS23225 d4cde63f7af2c51c0a022f44225a0450 343 SUPERFAMILY SSF54534 187 292 1.37E-35 T 29-03-2018 THSYN_RS18250 fd7bacf1c421dbdb4cd7ca959f8b1844 421 Gene3D G3DSA:1.20.1090.10 199 406 4.0E-57 T 29-03-2018 THSYN_RS18250 fd7bacf1c421dbdb4cd7ca959f8b1844 421 SUPERFAMILY SSF56796 25 396 2.09E-109 T 29-03-2018 THSYN_RS18250 fd7bacf1c421dbdb4cd7ca959f8b1844 421 Pfam PF00465 Iron-containing alcohol dehydrogenase 27 388 7.3E-108 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 THSYN_RS18250 fd7bacf1c421dbdb4cd7ca959f8b1844 421 Gene3D G3DSA:3.40.50.1970 26 198 7.4E-43 T 29-03-2018 THSYN_RS21715 cc255e35d592c2d2ca041ec00c6f2723 379 Gene3D G3DSA:1.20.1250.20 186 379 3.8E-19 T 29-03-2018 THSYN_RS21715 cc255e35d592c2d2ca041ec00c6f2723 379 Gene3D G3DSA:1.20.1250.20 2 182 5.3E-15 T 29-03-2018 THSYN_RS21715 cc255e35d592c2d2ca041ec00c6f2723 379 SUPERFAMILY SSF103473 3 374 1.83E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS21715 cc255e35d592c2d2ca041ec00c6f2723 379 PIRSF PIRSF004925 2 378 3.1E-100 T 29-03-2018 IPR026032 Probable 3-phenylpropionic acid transporter THSYN_RS21715 cc255e35d592c2d2ca041ec00c6f2723 379 Pfam PF12832 MFS_1 like family 3 355 1.3E-86 T 29-03-2018 IPR024989 Major facilitator superfamily associated domain THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 Gene3D G3DSA:3.30.70.940 2 115 1.4E-42 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 Pfam PF00467 KOW motif 126 156 7.8E-9 T 29-03-2018 IPR005824 KOW THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 SMART SM00738 2 111 6.7E-47 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 Gene3D G3DSA:2.30.30.30 118 176 4.7E-20 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 1.2E-66 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 29-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 Pfam PF02357 Transcription termination factor nusG 3 108 4.5E-27 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 SUPERFAMILY SSF82679 3 113 1.96E-39 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 25.098 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 SUPERFAMILY SSF50104 121 176 1.4E-18 T 29-03-2018 IPR008991 Translation protein SH3-like domain THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 SMART SM00739 123 150 7.1E-6 T 29-03-2018 IPR005824 KOW THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 5.2E-19 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 5.2E-19 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THSYN_RS05695 bed11f8e90ba6f71bceac7c33899b53f 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 5.2E-19 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THSYN_RS19050 1f43642b26a3be6edd7ec01fb5cc1523 184 PRINTS PR00344 Bacterial sensor protein C-terminal signature 168 181 2.3E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS19050 1f43642b26a3be6edd7ec01fb5cc1523 184 PRINTS PR00344 Bacterial sensor protein C-terminal signature 143 161 2.3E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS19050 1f43642b26a3be6edd7ec01fb5cc1523 184 PRINTS PR00344 Bacterial sensor protein C-terminal signature 129 139 2.3E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS19050 1f43642b26a3be6edd7ec01fb5cc1523 184 PRINTS PR00344 Bacterial sensor protein C-terminal signature 111 125 2.3E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS19050 1f43642b26a3be6edd7ec01fb5cc1523 184 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 77 177 1.1E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS19050 1f43642b26a3be6edd7ec01fb5cc1523 184 Gene3D G3DSA:3.30.565.10 1 182 1.5E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS19050 1f43642b26a3be6edd7ec01fb5cc1523 184 SUPERFAMILY SSF55874 21 180 3.01E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS19050 1f43642b26a3be6edd7ec01fb5cc1523 184 SMART SM00387 74 184 4.8E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS31405 90ed422b7564640a3c38774b5321a514 194 Gene3D G3DSA:3.90.79.10 19 191 3.6E-30 T 29-03-2018 THSYN_RS31405 90ed422b7564640a3c38774b5321a514 194 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 24 194 29.939 T 29-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 THSYN_RS31405 90ed422b7564640a3c38774b5321a514 194 Pfam PF00293 NUDIX domain 50 180 2.6E-24 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THSYN_RS31405 90ed422b7564640a3c38774b5321a514 194 SUPERFAMILY SSF55811 24 189 6.91E-44 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 THSYN_RS31405 90ed422b7564640a3c38774b5321a514 194 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 26 183 2.1E-38 T 29-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 THSYN_RS31405 90ed422b7564640a3c38774b5321a514 194 PIRSF PIRSF018427 14 194 2.6E-51 T 29-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 THSYN_RS12950 fe6165f2b4301f7fdf0c425a6cc3fe9e 79 SUPERFAMILY SSF46785 1 73 4.12E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS12950 fe6165f2b4301f7fdf0c425a6cc3fe9e 79 Pfam PF09012 FeoC like transcriptional regulator 2 70 5.6E-21 T 29-03-2018 IPR015102 Transcriptional regulator HTH-type, FeoC THSYN_RS12950 fe6165f2b4301f7fdf0c425a6cc3fe9e 79 Gene3D G3DSA:1.10.10.10 1 72 1.3E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS31525 999dd16646ac710276062665651ffac6 873 SMART SM00831 37 107 8.7E-14 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 Gene3D G3DSA:2.70.150.10 44 243 7.5E-43 T 29-03-2018 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 Gene3D G3DSA:3.40.1110.10 310 500 1.2E-24 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 SUPERFAMILY SSF81665 45 145 1.1E-77 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 SUPERFAMILY SSF81665 647 854 1.1E-77 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 SUPERFAMILY SSF81665 242 344 1.1E-77 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 Pfam PF00702 haloacid dehalogenase-like hydrolase 346 612 7.4E-21 T 29-03-2018 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 Pfam PF00122 E1-E2 ATPase 146 329 2.5E-45 T 29-03-2018 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 TIGRFAM TIGR01647 ATPase-IIIA_H: plasma-membrane proton-efflux P-type ATPase 54 816 9.1E-281 T 29-03-2018 IPR006534 P-type ATPase, subfamily IIIA GO:0006754|GO:0016021|GO:0016887 KEGG: 00190+3.6.3.6 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 Pfam PF00690 Cation transporter/ATPase, N-terminus 45 102 7.1E-13 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 SUPERFAMILY SSF56784 435 647 1.46E-38 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS31525 999dd16646ac710276062665651ffac6 873 SUPERFAMILY SSF56784 346 402 1.46E-38 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS31525 999dd16646ac710276062665651ffac6 873 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 115 539 1.2E-54 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 564 685 4.2E-28 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 570 586 5.7E-39 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 598 614 5.7E-39 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 629 654 5.7E-39 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 769 790 5.7E-39 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 462 480 5.7E-39 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 352 358 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 Gene3D G3DSA:1.20.1110.10 506 852 4.5E-58 T 29-03-2018 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 SUPERFAMILY SSF81653 146 242 1.44E-28 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 621 633 1.5E-38 T 29-03-2018 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 515 525 1.5E-38 T 29-03-2018 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 192 206 1.5E-38 T 29-03-2018 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 493 504 1.5E-38 T 29-03-2018 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 350 364 1.5E-38 T 29-03-2018 THSYN_RS31525 999dd16646ac710276062665651ffac6 873 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 598 617 1.5E-38 T 29-03-2018 THSYN_RS10945 e7a3b60a6eca0ab3022ef2e50c34a17b 165 SUPERFAMILY SSF143880 6 86 3.53E-16 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS10945 e7a3b60a6eca0ab3022ef2e50c34a17b 165 Pfam PF10387 Protein of unknown function (DUF2442) 9 81 3.4E-9 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS10945 e7a3b60a6eca0ab3022ef2e50c34a17b 165 Gene3D G3DSA:3.30.2020.10 2 85 9.7E-17 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS10945 e7a3b60a6eca0ab3022ef2e50c34a17b 165 Gene3D G3DSA:1.10.260.40 87 165 1.0E-6 T 29-03-2018 THSYN_RS10945 e7a3b60a6eca0ab3022ef2e50c34a17b 165 SUPERFAMILY SSF47413 91 154 2.36E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 Pfam PF00656 Caspase domain 794 1023 7.7E-8 T 29-03-2018 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 Gene3D G3DSA:3.40.50.1460 785 1038 2.9E-29 T 29-03-2018 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 SUPERFAMILY SSF101908 41 332 3.27E-34 T 29-03-2018 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 Gene3D G3DSA:2.120.10.60 108 252 7.8E-18 T 29-03-2018 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 SUPERFAMILY SSF52129 846 1025 5.93E-6 T 29-03-2018 IPR029030 Caspase-like domain THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 Pfam PF00400 WD domain, G-beta repeat 40 70 1.0E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 SMART SM00320 134 173 30.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 SMART SM00320 186 224 51.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 SMART SM00320 82 131 2.9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 SMART SM00320 30 71 9.8E-5 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 SMART SM00320 252 293 22.0 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 SMART SM00320 532 570 7.1 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 Gene3D G3DSA:1.10.10.670 68 107 1.0E-7 T 29-03-2018 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 Gene3D G3DSA:2.40.50.140 34 67 4.6E-6 T 29-03-2018 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 Gene3D G3DSA:2.130.10.10 253 462 8.5E-11 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 Gene3D G3DSA:2.115.10.10 497 718 2.5E-7 T 29-03-2018 THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 SUPERFAMILY SSF50998 260 449 1.33E-19 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS11360 e3e20a9d02a4ee5cf382ce36d3c00ebb 1043 SUPERFAMILY SSF50998 525 613 1.33E-19 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS09625 47c66d3d90272adc2cba4f39455778eb 155 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 7 147 3.5E-23 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS09625 47c66d3d90272adc2cba4f39455778eb 155 SUPERFAMILY SSF53163 5 150 3.79E-28 T 29-03-2018 IPR023430 Peptidase HybD-like domain THSYN_RS09625 47c66d3d90272adc2cba4f39455778eb 155 Gene3D G3DSA:3.40.50.1450 2 154 2.2E-32 T 29-03-2018 IPR023430 Peptidase HybD-like domain THSYN_RS09625 47c66d3d90272adc2cba4f39455778eb 155 Pfam PF01750 Hydrogenase maturation protease 47 144 3.7E-5 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS07685 fb434628936f7b904f54374c9cdd4a50 327 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 86 323 6.7E-52 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 THSYN_RS07685 fb434628936f7b904f54374c9cdd4a50 327 SUPERFAMILY SSF46785 3 58 4.22E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07685 fb434628936f7b904f54374c9cdd4a50 327 Gene3D G3DSA:2.30.30.100 279 324 5.3E-13 T 29-03-2018 THSYN_RS07685 fb434628936f7b904f54374c9cdd4a50 327 Pfam PF08279 HTH domain 6 57 5.4E-9 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 THSYN_RS07685 fb434628936f7b904f54374c9cdd4a50 327 SUPERFAMILY SSF50037 279 324 5.95E-9 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal THSYN_RS07685 fb434628936f7b904f54374c9cdd4a50 327 SUPERFAMILY SSF55681 84 274 1.59E-51 T 29-03-2018 THSYN_RS07685 fb434628936f7b904f54374c9cdd4a50 327 Gene3D G3DSA:3.30.930.10 71 277 1.9E-55 T 29-03-2018 THSYN_RS07685 fb434628936f7b904f54374c9cdd4a50 327 Gene3D G3DSA:1.10.10.10 1 62 1.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07685 fb434628936f7b904f54374c9cdd4a50 327 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 4 324 31.653 T 29-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 THSYN_RS07685 fb434628936f7b904f54374c9cdd4a50 327 Pfam PF03099 Biotin/lipoate A/B protein ligase family 93 213 9.0E-13 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 THSYN_RS07685 fb434628936f7b904f54374c9cdd4a50 327 Pfam PF02237 Biotin protein ligase C terminal domain 280 324 1.0E-8 T 29-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 THSYN_RS07440 bf022b08f3f18bf4fffb68efe8cbc9bf 65 Pfam PF10049 Protein of unknown function (DUF2283) 4 49 2.1E-9 T 29-03-2018 IPR019270 Protein of unknown function DUF2283 THSYN_RS09860 a9137404018aa7ea61e1f69b0dd38cf2 364 Gene3D G3DSA:3.40.220.10 1 339 1.8E-35 T 29-03-2018 THSYN_RS09860 a9137404018aa7ea61e1f69b0dd38cf2 364 Pfam PF01661 Macro domain 18 129 3.0E-16 T 29-03-2018 IPR002589 Macro domain THSYN_RS09860 a9137404018aa7ea61e1f69b0dd38cf2 364 SMART SM00506 1 132 6.1E-18 T 29-03-2018 IPR002589 Macro domain THSYN_RS09860 a9137404018aa7ea61e1f69b0dd38cf2 364 SUPERFAMILY SSF52949 2 149 1.04E-42 T 29-03-2018 THSYN_RS23460 0b5402e435ad44d97a36b48b3513f54c 624 SUPERFAMILY SSF56601 250 611 1.38E-100 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS23460 0b5402e435ad44d97a36b48b3513f54c 624 Gene3D G3DSA:3.90.1310.10 33 245 8.9E-50 T 29-03-2018 THSYN_RS23460 0b5402e435ad44d97a36b48b3513f54c 624 Pfam PF03717 Penicillin-binding Protein dimerisation domain 64 235 2.3E-43 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 THSYN_RS23460 0b5402e435ad44d97a36b48b3513f54c 624 SUPERFAMILY SSF56519 56 248 4.97E-48 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 THSYN_RS23460 0b5402e435ad44d97a36b48b3513f54c 624 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 20 610 8.8E-228 T 29-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 THSYN_RS23460 0b5402e435ad44d97a36b48b3513f54c 624 Pfam PF00905 Penicillin binding protein transpeptidase domain 267 606 1.2E-77 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THSYN_RS23460 0b5402e435ad44d97a36b48b3513f54c 624 Gene3D G3DSA:3.40.710.10 246 614 1.7E-92 T 29-03-2018 THSYN_RS11325 117cd7a5eb9b18e7c272394312f27adb 677 Gene3D G3DSA:1.20.1050.40 4 135 3.2E-38 T 29-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal THSYN_RS11325 117cd7a5eb9b18e7c272394312f27adb 677 Pfam PF01432 Peptidase family M3 219 674 3.1E-147 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 THSYN_RS11325 117cd7a5eb9b18e7c272394312f27adb 677 SUPERFAMILY SSF55486 1 674 2.04E-199 T 29-03-2018 THSYN_RS11325 117cd7a5eb9b18e7c272394312f27adb 677 Gene3D G3DSA:1.10.1370.10 455 677 1.9E-63 T 29-03-2018 THSYN_RS11325 117cd7a5eb9b18e7c272394312f27adb 677 Gene3D G3DSA:1.10.1370.10 137 440 1.1E-57 T 29-03-2018 THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 Gene3D G3DSA:3.30.230.10 287 458 5.5E-28 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 Gene3D G3DSA:3.40.50.300 76 286 1.6E-40 T 29-03-2018 THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 SUPERFAMILY SSF52540 72 297 1.85E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 Hamap MF_01498 DNA repair protein RadA [radA]. 25 456 43.11 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 SUPERFAMILY SSF54211 307 456 9.86E-39 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 SUPERFAMILY SSF54211 259 273 9.86E-39 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 Pfam PF13481 AAA domain 89 226 2.8E-14 T 29-03-2018 THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 TIGRFAM TIGR00416 sms: DNA repair protein RadA 7 455 9.6E-186 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 PRINTS PR01874 DNA repair protein radA signature 178 202 4.8E-93 T 29-03-2018 THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 PRINTS PR01874 DNA repair protein radA signature 87 115 4.8E-93 T 29-03-2018 THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 PRINTS PR01874 DNA repair protein radA signature 128 145 4.8E-93 T 29-03-2018 THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 PRINTS PR01874 DNA repair protein radA signature 217 245 4.8E-93 T 29-03-2018 THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 PRINTS PR01874 DNA repair protein radA signature 252 278 4.8E-93 T 29-03-2018 THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 PRINTS PR01874 DNA repair protein radA signature 326 349 4.8E-93 T 29-03-2018 THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 PRINTS PR01874 DNA repair protein radA signature 14 38 4.8E-93 T 29-03-2018 THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 SMART SM00382 95 248 1.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS13560 3db63231a88fd73c5bf16bbfcd8e86e4 458 Pfam PF13541 Subunit ChlI of Mg-chelatase 352 434 3.3E-8 T 29-03-2018 THSYN_RS14920 4304433fa9e53c61145a624ee8905a15 351 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 4 350 38.461 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 THSYN_RS14920 4304433fa9e53c61145a624ee8905a15 351 Pfam PF01008 Initiation factor 2 subunit family 54 338 3.3E-71 T 29-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 THSYN_RS14920 4304433fa9e53c61145a624ee8905a15 351 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 16 338 8.6E-129 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 THSYN_RS14920 4304433fa9e53c61145a624ee8905a15 351 SUPERFAMILY SSF100950 11 342 1.19E-109 T 29-03-2018 THSYN_RS14920 4304433fa9e53c61145a624ee8905a15 351 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 44 338 1.7E-104 T 29-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 THSYN_RS14920 4304433fa9e53c61145a624ee8905a15 351 Gene3D G3DSA:3.40.50.10470 146 349 4.0E-61 T 29-03-2018 THSYN_RS14920 4304433fa9e53c61145a624ee8905a15 351 Gene3D G3DSA:1.20.120.420 12 145 1.6E-40 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 THSYN_RS15385 df9a0d6ae7ab71047f3eefb52e2275d5 155 TIGRFAM TIGR00498 lexA: repressor LexA 33 153 8.3E-35 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 THSYN_RS15385 df9a0d6ae7ab71047f3eefb52e2275d5 155 Pfam PF00717 Peptidase S24-like 70 137 6.0E-16 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THSYN_RS15385 df9a0d6ae7ab71047f3eefb52e2275d5 155 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 78 89 6.5E-6 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THSYN_RS15385 df9a0d6ae7ab71047f3eefb52e2275d5 155 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 67 77 6.5E-6 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THSYN_RS15385 df9a0d6ae7ab71047f3eefb52e2275d5 155 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 107 119 6.5E-6 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THSYN_RS15385 df9a0d6ae7ab71047f3eefb52e2275d5 155 SUPERFAMILY SSF51306 32 152 2.09E-29 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THSYN_RS15385 df9a0d6ae7ab71047f3eefb52e2275d5 155 Gene3D G3DSA:2.10.109.10 38 153 5.9E-23 T 29-03-2018 THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 SMART SM00490 526 610 1.8E-19 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 Gene3D G3DSA:3.40.50.300 276 478 7.0E-35 T 29-03-2018 THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 SMART SM00487 287 481 1.3E-26 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 SUPERFAMILY SSF52540 238 474 4.38E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 Gene3D G3DSA:1.10.150.20 15 68 1.8E-5 T 29-03-2018 THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 Gene3D G3DSA:3.40.50.300 479 651 4.4E-27 T 29-03-2018 THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 Pfam PF00271 Helicase conserved C-terminal domain 503 609 1.1E-14 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 Pfam PF17191 RecG wedge domain 26 190 1.2E-10 T 29-03-2018 IPR033454 RecG, wedge domain THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 SUPERFAMILY SSF50249 21 195 1.44E-30 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 Pfam PF00270 DEAD/DEAH box helicase 293 452 1.2E-13 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 40 685 4.6E-205 T 29-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 Gene3D G3DSA:2.40.50.140 69 162 8.3E-9 T 29-03-2018 THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 SUPERFAMILY SSF52540 312 364 6.19E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07765 5d2e804a538be6f96b46cf59ce236f52 714 SUPERFAMILY SSF52540 529 671 6.19E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08230 c1a03620f6afdc9187cb446bbf37863c 369 TIGRFAM TIGR03694 exosort_acyl: N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated 134 363 2.1E-62 T 29-03-2018 IPR022484 PEP-CTERM/exosortase system-associated acyltransferase, predicted THSYN_RS08230 c1a03620f6afdc9187cb446bbf37863c 369 SUPERFAMILY SSF55729 137 342 2.22E-31 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS08230 c1a03620f6afdc9187cb446bbf37863c 369 Pfam PF13444 Acetyltransferase (GNAT) domain 157 263 1.4E-16 T 29-03-2018 THSYN_RS08230 c1a03620f6afdc9187cb446bbf37863c 369 Gene3D G3DSA:3.40.630.30 138 352 1.3E-34 T 29-03-2018 THSYN_RS15700 443fe19e7be26a727cf5b189f6754586 261 SMART SM00448 10 121 3.4E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS15700 443fe19e7be26a727cf5b189f6754586 261 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 236 8.0E-9 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS15700 443fe19e7be26a727cf5b189f6754586 261 SMART SM00862 159 237 1.4E-5 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS15700 443fe19e7be26a727cf5b189f6754586 261 SUPERFAMILY SSF52172 11 151 3.13E-30 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS15700 443fe19e7be26a727cf5b189f6754586 261 Gene3D G3DSA:3.40.50.2300 1 141 1.2E-28 T 29-03-2018 THSYN_RS15700 443fe19e7be26a727cf5b189f6754586 261 SUPERFAMILY SSF46894 153 238 2.41E-11 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS15700 443fe19e7be26a727cf5b189f6754586 261 Gene3D G3DSA:1.10.10.10 142 244 1.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS15700 443fe19e7be26a727cf5b189f6754586 261 Pfam PF00072 Response regulator receiver domain 12 120 3.8E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS32295 49b5f9db926e15fe471bafcca9c0dbc4 245 SUPERFAMILY SSF52540 1 216 5.44E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS32295 49b5f9db926e15fe471bafcca9c0dbc4 245 Pfam PF00005 ABC transporter 19 163 7.2E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS32295 49b5f9db926e15fe471bafcca9c0dbc4 245 Gene3D G3DSA:3.40.50.300 1 233 4.1E-61 T 29-03-2018 THSYN_RS32295 49b5f9db926e15fe471bafcca9c0dbc4 245 SMART SM00382 26 213 1.1E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS32295 49b5f9db926e15fe471bafcca9c0dbc4 245 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 SUPERFAMILY SSF49299 248 340 7.06E-8 T 29-03-2018 IPR000601 PKD domain THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 Gene3D G3DSA:3.40.1850.10 163 259 3.0E-20 T 29-03-2018 THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 Gene3D G3DSA:3.40.1850.10 260 355 1.6E-21 T 29-03-2018 THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 Gene3D G3DSA:3.40.1850.10 356 446 2.7E-14 T 29-03-2018 THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 Pfam PF02010 REJ domain 315 457 3.2E-9 T 29-03-2018 IPR002859 PKD/REJ-like domain THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 Pfam PF00801 PKD domain 731 796 2.0E-6 T 29-03-2018 IPR000601 PKD domain THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 Pfam PF00801 PKD domain 633 704 1.9E-5 T 29-03-2018 IPR000601 PKD domain THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 SUPERFAMILY SSF49299 514 623 2.35E-13 T 29-03-2018 IPR000601 PKD domain THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 SMART SM00089 159 245 6.0 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 SMART SM00089 538 625 2.0E-7 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 SMART SM00089 722 809 2.4E-14 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 SMART SM00089 628 715 3.6E-10 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 SMART SM00089 250 342 8.8E-8 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 SUPERFAMILY SSF49299 151 245 7.85E-6 T 29-03-2018 IPR000601 PKD domain THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 Gene3D G3DSA:2.60.40.10 1142 1262 0.026 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 SUPERFAMILY SSF49299 624 711 5.62E-15 T 29-03-2018 IPR000601 PKD domain THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 Gene3D G3DSA:2.60.40.10 447 535 7.3E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 Gene3D G3DSA:2.60.120.260 825 948 1.7E-8 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 SUPERFAMILY SSF49785 828 899 1.82E-6 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 Gene3D G3DSA:2.60.40.10 625 717 1.1E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 Gene3D G3DSA:2.60.40.10 537 624 1.1E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 Gene3D G3DSA:2.60.40.10 718 812 1.7E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 Pfam PF13860 FlgD Ig-like domain 969 1019 6.8E-7 T 29-03-2018 IPR025965 FlgD Ig-like domain THSYN_RS14595 0d53df3505b58498ae3b8a5e4e46b0bd 1266 SUPERFAMILY SSF49299 720 806 7.85E-16 T 29-03-2018 IPR000601 PKD domain THSYN_RS19275 37efd70281685c526813a7bf1601f0ba 292 SUPERFAMILY SSF52540 109 290 3.49E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19275 37efd70281685c526813a7bf1601f0ba 292 SUPERFAMILY SSF52540 1 65 3.49E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19275 37efd70281685c526813a7bf1601f0ba 292 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 267 7.7E-16 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THSYN_RS19275 37efd70281685c526813a7bf1601f0ba 292 Gene3D G3DSA:3.40.50.300 1 290 1.6E-38 T 29-03-2018 THSYN_RS19275 37efd70281685c526813a7bf1601f0ba 292 Pfam PF00037 4Fe-4S binding domain 62 84 3.2E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS19275 37efd70281685c526813a7bf1601f0ba 292 Pfam PF00037 4Fe-4S binding domain 93 114 7.1E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS19275 37efd70281685c526813a7bf1601f0ba 292 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 98 109 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS19275 37efd70281685c526813a7bf1601f0ba 292 SUPERFAMILY SSF54862 59 115 2.3E-17 T 29-03-2018 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 Pfam PF00871 Acetokinase family 5 390 1.5E-95 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 PRINTS PR00471 Acetate kinase family signature 209 230 1.5E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 PRINTS PR00471 Acetate kinase family signature 377 389 1.5E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 PRINTS PR00471 Acetate kinase family signature 5 16 1.5E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 PRINTS PR00471 Acetate kinase family signature 303 316 1.5E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 PRINTS PR00471 Acetate kinase family signature 180 193 1.5E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 PRINTS PR00471 Acetate kinase family signature 325 341 1.5E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 PIRSF PIRSF000722 1 399 1.6E-126 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 209 226 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 SUPERFAMILY SSF53067 166 398 3.19E-74 T 29-03-2018 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 Hamap MF_00020 Acetate kinase [ackA]. 1 399 151.345 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 Gene3D G3DSA:3.30.420.40 203 399 3.5E-70 T 29-03-2018 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 SUPERFAMILY SSF53067 4 202 4.14E-53 T 29-03-2018 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 TIGRFAM TIGR00016 ackA: acetate kinase 3 396 6.8E-97 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 Gene3D G3DSA:3.30.420.40 4 201 3.7E-54 T 29-03-2018 THSYN_RS31010 7f31980a1bfb200dae5ed03de84efae6 399 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THSYN_RS00980 053c19458f9136033d67111797b5045a 511 Gene3D G3DSA:3.40.1020.10 328 507 1.3E-65 T 29-03-2018 THSYN_RS00980 053c19458f9136033d67111797b5045a 511 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 5 505 2.5E-236 T 29-03-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 THSYN_RS00980 053c19458f9136033d67111797b5045a 511 Gene3D G3DSA:3.40.50.1100 4 157 9.3E-44 T 29-03-2018 THSYN_RS00980 053c19458f9136033d67111797b5045a 511 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 THSYN_RS00980 053c19458f9136033d67111797b5045a 511 SUPERFAMILY SSF55021 327 413 5.27E-27 T 29-03-2018 THSYN_RS00980 053c19458f9136033d67111797b5045a 511 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 306 3.4E-80 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THSYN_RS00980 053c19458f9136033d67111797b5045a 511 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 426 503 2.4E-20 T 29-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 THSYN_RS00980 053c19458f9136033d67111797b5045a 511 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 319 409 9.6E-23 T 29-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 THSYN_RS00980 053c19458f9136033d67111797b5045a 511 Gene3D G3DSA:3.40.50.1100 158 324 3.7E-38 T 29-03-2018 THSYN_RS00980 053c19458f9136033d67111797b5045a 511 SUPERFAMILY SSF55021 410 505 2.82E-24 T 29-03-2018 THSYN_RS00980 053c19458f9136033d67111797b5045a 511 SUPERFAMILY SSF53686 4 355 1.31E-103 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THSYN_RS26970 3ec8ea11752b1adb70fd0078f4a70589 223 PIRSF PIRSF006102 1 216 1.1E-67 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 THSYN_RS26970 3ec8ea11752b1adb70fd0078f4a70589 223 Pfam PF02508 Rnf-Nqr subunit, membrane protein 8 200 7.4E-58 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 THSYN_RS26970 3ec8ea11752b1adb70fd0078f4a70589 223 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 8 208 1.3E-72 T 29-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 THSYN_RS26970 3ec8ea11752b1adb70fd0078f4a70589 223 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 5 211 26.104 T 29-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 THSYN_RS10260 a3c40130922290c802a2edb829c2faa1 206 SMART SM00448 5 116 8.7E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS10260 a3c40130922290c802a2edb829c2faa1 206 SUPERFAMILY SSF46894 130 200 1.56E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS10260 a3c40130922290c802a2edb829c2faa1 206 ProSitePatterns PS00622 LuxR-type HTH domain signature. 157 184 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS10260 a3c40130922290c802a2edb829c2faa1 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 1.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS10260 a3c40130922290c802a2edb829c2faa1 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 1.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS10260 a3c40130922290c802a2edb829c2faa1 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 1.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS10260 a3c40130922290c802a2edb829c2faa1 206 Gene3D G3DSA:3.40.50.2300 1 127 1.1E-31 T 29-03-2018 THSYN_RS10260 a3c40130922290c802a2edb829c2faa1 206 Gene3D G3DSA:1.10.10.10 128 201 2.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS10260 a3c40130922290c802a2edb829c2faa1 206 SMART SM00421 140 197 7.8E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS10260 a3c40130922290c802a2edb829c2faa1 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 197 1.6E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS10260 a3c40130922290c802a2edb829c2faa1 206 SUPERFAMILY SSF52172 6 150 1.85E-35 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS10260 a3c40130922290c802a2edb829c2faa1 206 Pfam PF00072 Response regulator receiver domain 7 116 8.4E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS06350 493289259e80eccfa8a38e9bfda53891 260 SUPERFAMILY SSF51735 11 259 6.82E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS06350 493289259e80eccfa8a38e9bfda53891 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 257 1.5E-78 T 29-03-2018 THSYN_RS06350 493289259e80eccfa8a38e9bfda53891 260 PIRSF PIRSF000094 7 260 1.6E-88 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THSYN_RS06350 493289259e80eccfa8a38e9bfda53891 260 Gene3D G3DSA:3.40.50.720 9 260 2.4E-42 T 29-03-2018 THSYN_RS06350 493289259e80eccfa8a38e9bfda53891 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.2E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS06350 493289259e80eccfa8a38e9bfda53891 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.2E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS06350 493289259e80eccfa8a38e9bfda53891 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.2E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS06350 493289259e80eccfa8a38e9bfda53891 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.2E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS28930 162efb13895c1e45c4762c59d4e635e5 519 Gene3D G3DSA:3.40.640.10 154 391 7.4E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS28930 162efb13895c1e45c4762c59d4e635e5 519 Gene3D G3DSA:3.90.1150.10 392 519 1.3E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS28930 162efb13895c1e45c4762c59d4e635e5 519 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 171 513 5.5E-120 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THSYN_RS28930 162efb13895c1e45c4762c59d4e635e5 519 SUPERFAMILY SSF53383 164 518 2.95E-111 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS05985 e0f72ef856b3b1fde8042e59d654dd67 358 Pfam PF13365 Trypsin-like peptidase domain 224 325 2.5E-21 T 29-03-2018 THSYN_RS05985 e0f72ef856b3b1fde8042e59d654dd67 358 Gene3D G3DSA:2.40.10.10 72 271 6.6E-20 T 29-03-2018 THSYN_RS05985 e0f72ef856b3b1fde8042e59d654dd67 358 Pfam PF13511 Domain of unknown function (DUF4124) 20 70 2.3E-7 T 29-03-2018 IPR025392 Domain of unknown function DUF4124 THSYN_RS05985 e0f72ef856b3b1fde8042e59d654dd67 358 SUPERFAMILY SSF50494 82 121 1.46E-39 T 29-03-2018 IPR009003 Peptidase S1, PA clan THSYN_RS05985 e0f72ef856b3b1fde8042e59d654dd67 358 SUPERFAMILY SSF50494 220 356 1.46E-39 T 29-03-2018 IPR009003 Peptidase S1, PA clan THSYN_RS05985 e0f72ef856b3b1fde8042e59d654dd67 358 Gene3D G3DSA:2.40.10.10 272 358 2.2E-23 T 29-03-2018 THSYN_RS30575 c3d0bc051323c6f6400903b95c561e75 330 Pfam PF13439 Glycosyltransferase Family 4 56 134 2.8E-8 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS30575 c3d0bc051323c6f6400903b95c561e75 330 Gene3D G3DSA:3.40.50.2000 131 302 1.3E-39 T 29-03-2018 THSYN_RS30575 c3d0bc051323c6f6400903b95c561e75 330 Pfam PF00534 Glycosyl transferases group 1 137 298 1.0E-27 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS30575 c3d0bc051323c6f6400903b95c561e75 330 SUPERFAMILY SSF53756 58 323 9.42E-58 T 29-03-2018 THSYN_RS11510 cb0cb2a57a6d850452ae660a113b060b 584 TIGRFAM TIGR03354 VI_FHA: type VI secretion system FHA domain protein 299 563 1.7E-61 T 29-03-2018 IPR017735 Type VI secretion system, FHA domain-containing protein THSYN_RS11510 cb0cb2a57a6d850452ae660a113b060b 584 Pfam PF00498 FHA domain 45 114 3.0E-14 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THSYN_RS11510 cb0cb2a57a6d850452ae660a113b060b 584 SMART SM00240 44 97 1.8E-5 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THSYN_RS11510 cb0cb2a57a6d850452ae660a113b060b 584 Gene3D G3DSA:2.60.200.20 24 122 5.3E-20 T 29-03-2018 THSYN_RS11510 cb0cb2a57a6d850452ae660a113b060b 584 SUPERFAMILY SSF49879 24 120 3.25E-22 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 THSYN_RS05705 d73af5ca6eb1cf1b26c9cac1686270bd 230 Gene3D G3DSA:3.40.50.790 68 149 3.8E-34 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich THSYN_RS05705 d73af5ca6eb1cf1b26c9cac1686270bd 230 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.469 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 THSYN_RS05705 d73af5ca6eb1cf1b26c9cac1686270bd 230 SUPERFAMILY SSF56808 6 225 4.84E-80 T 29-03-2018 IPR023674 Ribosomal protein L1-like THSYN_RS05705 d73af5ca6eb1cf1b26c9cac1686270bd 230 PIRSF PIRSF002155 1 227 4.3E-77 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS05705 d73af5ca6eb1cf1b26c9cac1686270bd 230 Gene3D G3DSA:3.30.190.20 150 227 2.9E-18 T 29-03-2018 THSYN_RS05705 d73af5ca6eb1cf1b26c9cac1686270bd 230 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 226 2.0E-102 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 THSYN_RS05705 d73af5ca6eb1cf1b26c9cac1686270bd 230 Pfam PF00687 Ribosomal protein L1p/L10e family 30 220 2.6E-51 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein THSYN_RS05705 d73af5ca6eb1cf1b26c9cac1686270bd 230 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS05010 62a38955470fe8210a62bff02127c447 181 Gene3D G3DSA:3.30.420.10 2 181 3.1E-23 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS05010 62a38955470fe8210a62bff02127c447 181 Pfam PF00929 Exonuclease 9 170 2.6E-29 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THSYN_RS05010 62a38955470fe8210a62bff02127c447 181 SUPERFAMILY SSF53098 1 179 7.09E-44 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS05010 62a38955470fe8210a62bff02127c447 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 41.34 T 29-03-2018 IPR022894 Oligoribonuclease GO:0000175 THSYN_RS05010 62a38955470fe8210a62bff02127c447 181 SMART SM00479 7 180 7.2E-17 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THSYN_RS11280 b57661e598c8a0267e998bc801e85870 147 Gene3D G3DSA:2.60.40.1180 13 76 4.2E-7 T 29-03-2018 THSYN_RS11280 b57661e598c8a0267e998bc801e85870 147 Gene3D G3DSA:2.60.40.1180 77 145 4.1E-22 T 29-03-2018 THSYN_RS11280 b57661e598c8a0267e998bc801e85870 147 SMART SM00671 76 111 5.3E-9 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS11280 b57661e598c8a0267e998bc801e85870 147 SMART SM00671 40 75 6.8E-4 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS11280 b57661e598c8a0267e998bc801e85870 147 SMART SM00671 112 147 0.034 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS11280 b57661e598c8a0267e998bc801e85870 147 Pfam PF08238 Sel1 repeat 40 71 2.8E-4 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS11280 b57661e598c8a0267e998bc801e85870 147 Pfam PF08238 Sel1 repeat 114 138 0.0022 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS11280 b57661e598c8a0267e998bc801e85870 147 Pfam PF08238 Sel1 repeat 78 110 8.2E-9 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS11280 b57661e598c8a0267e998bc801e85870 147 SUPERFAMILY SSF81901 14 138 3.92E-28 T 29-03-2018 THSYN_RS21265 7f4dfb512ab6724b696ac70b83a9075b 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 553 4.9E-299 T 29-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD THSYN_RS21265 7f4dfb512ab6724b696ac70b83a9075b 555 Gene3D G3DSA:3.40.50.300 290 552 9.1E-52 T 29-03-2018 THSYN_RS21265 7f4dfb512ab6724b696ac70b83a9075b 555 SMART SM00382 348 524 1.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS21265 7f4dfb512ab6724b696ac70b83a9075b 555 SMART SM00382 31 236 2.1E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS21265 7f4dfb512ab6724b696ac70b83a9075b 555 Pfam PF12848 ABC transporter 230 303 4.3E-11 T 29-03-2018 IPR032781 ABC-transporter extension domain THSYN_RS21265 7f4dfb512ab6724b696ac70b83a9075b 555 Gene3D G3DSA:3.40.50.300 12 289 4.6E-52 T 29-03-2018 THSYN_RS21265 7f4dfb512ab6724b696ac70b83a9075b 555 Pfam PF00005 ABC transporter 339 473 2.0E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS21265 7f4dfb512ab6724b696ac70b83a9075b 555 Pfam PF00005 ABC transporter 22 191 5.3E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS21265 7f4dfb512ab6724b696ac70b83a9075b 555 SUPERFAMILY SSF52540 302 525 4.43E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21265 7f4dfb512ab6724b696ac70b83a9075b 555 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS21265 7f4dfb512ab6724b696ac70b83a9075b 555 SUPERFAMILY SSF52540 12 244 2.85E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS25980 27cbbeaf191e9b24b176672c4e498c67 230 Pfam PF00551 Formyl transferase 12 188 8.9E-54 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THSYN_RS25980 27cbbeaf191e9b24b176672c4e498c67 230 Gene3D G3DSA:3.40.50.170 2 207 1.3E-61 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THSYN_RS25980 27cbbeaf191e9b24b176672c4e498c67 230 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 12 195 29.241 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 THSYN_RS25980 27cbbeaf191e9b24b176672c4e498c67 230 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 141 164 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THSYN_RS25980 27cbbeaf191e9b24b176672c4e498c67 230 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 13 198 3.7E-67 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 THSYN_RS25980 27cbbeaf191e9b24b176672c4e498c67 230 SUPERFAMILY SSF53328 12 202 4.45E-59 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THSYN_RS08825 731cf35e6ed850b4127f44f1ae9f4fc2 248 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 233 1.9E-63 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 THSYN_RS08825 731cf35e6ed850b4127f44f1ae9f4fc2 248 SUPERFAMILY SSF64167 1 246 8.24E-82 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 THSYN_RS08825 731cf35e6ed850b4127f44f1ae9f4fc2 248 Gene3D G3DSA:3.40.1210.10 1 248 6.4E-83 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 THSYN_RS08825 731cf35e6ed850b4127f44f1ae9f4fc2 248 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 248 38.505 T 29-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 THSYN_RS08825 731cf35e6ed850b4127f44f1ae9f4fc2 248 Pfam PF01975 Survival protein SurE 3 182 6.3E-56 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 THSYN_RS13500 c2a0facc092afbc0c4847c4f2ac9ecda 1290 SUPERFAMILY SSF52540 750 940 2.3E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13500 c2a0facc092afbc0c4847c4f2ac9ecda 1290 SUPERFAMILY SSF52540 424 497 2.3E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13500 c2a0facc092afbc0c4847c4f2ac9ecda 1290 Gene3D G3DSA:3.40.50.300 754 935 6.9E-28 T 29-03-2018 THSYN_RS13500 c2a0facc092afbc0c4847c4f2ac9ecda 1290 Gene3D G3DSA:3.40.50.300 291 501 6.0E-19 T 29-03-2018 THSYN_RS13500 c2a0facc092afbc0c4847c4f2ac9ecda 1290 SMART SM00487 293 496 0.0014 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS13500 c2a0facc092afbc0c4847c4f2ac9ecda 1290 SMART SM00490 789 886 7.5E-22 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS13500 c2a0facc092afbc0c4847c4f2ac9ecda 1290 SUPERFAMILY SSF52540 292 498 2.33E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13500 c2a0facc092afbc0c4847c4f2ac9ecda 1290 Pfam PF00271 Helicase conserved C-terminal domain 760 886 2.5E-17 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS30560 2b9034584c47b2df22f5cdacbf0f7966 324 SUPERFAMILY SSF53597 103 274 1.01E-44 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 THSYN_RS30560 2b9034584c47b2df22f5cdacbf0f7966 324 Gene3D G3DSA:3.40.430.10 79 307 3.4E-50 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 THSYN_RS30560 2b9034584c47b2df22f5cdacbf0f7966 324 Pfam PF01872 RibD C-terminal domain 106 275 6.3E-38 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 THSYN_RS20420 d1f152089d8c869d4b9dbfaa940a4b3e 109 Pfam PF03683 Uncharacterised protein family (UPF0175) 51 99 1.3E-8 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS20420 d1f152089d8c869d4b9dbfaa940a4b3e 109 Gene3D G3DSA:3.40.1620.10 1 104 4.0E-6 T 29-03-2018 THSYN_RS15060 14747b72b40a7ab769f657501da75083 856 SUPERFAMILY SSF53300 39 171 2.07E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS15060 14747b72b40a7ab769f657501da75083 856 SUPERFAMILY SSF53300 389 556 9.64E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS15060 14747b72b40a7ab769f657501da75083 856 Pfam PF13768 von Willebrand factor type A domain 390 546 3.4E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS15060 14747b72b40a7ab769f657501da75083 856 SUPERFAMILY SSF52317 570 663 1.83E-27 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS15060 14747b72b40a7ab769f657501da75083 856 SUPERFAMILY SSF52317 262 386 1.83E-27 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS15060 14747b72b40a7ab769f657501da75083 856 Gene3D G3DSA:3.40.50.410 34 270 9.9E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS15060 14747b72b40a7ab769f657501da75083 856 Gene3D G3DSA:3.40.50.410 384 566 5.3E-22 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS15060 14747b72b40a7ab769f657501da75083 856 SMART SM00327 39 238 0.11 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS15060 14747b72b40a7ab769f657501da75083 856 SMART SM00327 388 566 2.6E-18 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS29040 cf43cf22e631cc3504f91788ad1b23e7 286 Gene3D G3DSA:3.40.50.720 1 283 2.1E-23 T 29-03-2018 THSYN_RS29040 cf43cf22e631cc3504f91788ad1b23e7 286 Pfam PF04321 RmlD substrate binding domain 1 150 2.0E-26 T 29-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 THSYN_RS29040 cf43cf22e631cc3504f91788ad1b23e7 286 SUPERFAMILY SSF51735 1 283 4.09E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 SUPERFAMILY SSF55874 462 632 1.31E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 Gene3D G3DSA:3.40.50.2300 656 786 1.1E-39 T 29-03-2018 THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 Gene3D G3DSA:1.10.287.130 397 469 2.6E-20 T 29-03-2018 THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 Gene3D G3DSA:3.30.450.20 189 312 2.9E-11 T 29-03-2018 THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 PRINTS PR00344 Bacterial sensor protein C-terminal signature 579 589 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 PRINTS PR00344 Bacterial sensor protein C-terminal signature 561 575 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 PRINTS PR00344 Bacterial sensor protein C-terminal signature 620 633 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 PRINTS PR00344 Bacterial sensor protein C-terminal signature 596 614 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 SMART SM00387 520 636 5.9E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 SUPERFAMILY SSF47384 391 474 1.18E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 Gene3D G3DSA:3.30.565.10 477 640 1.2E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 SUPERFAMILY SSF52172 666 786 2.28E-36 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 SMART SM00388 407 473 2.1E-24 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 SMART SM00448 665 782 1.4E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 Pfam PF00512 His Kinase A (phospho-acceptor) domain 407 473 1.4E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 520 634 2.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02230 a11c3bcd4b2ff4455cef7f0a47c570f9 788 Pfam PF00072 Response regulator receiver domain 667 782 6.1E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00395 305705cb57f0ccfeeba7640ae830c8eb 391 SUPERFAMILY SSF56935 25 391 6.96E-21 T 29-03-2018 THSYN_RS00395 305705cb57f0ccfeeba7640ae830c8eb 391 Pfam PF00593 TonB dependent receptor 245 359 0.0012 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THSYN_RS00395 305705cb57f0ccfeeba7640ae830c8eb 391 Gene3D G3DSA:2.40.160.10 8 391 1.1E-40 T 29-03-2018 THSYN_RS28250 dc81fd53d88d1d23bdf5372e7b2b929a 175 Gene3D G3DSA:3.30.160.150 30 174 2.1E-31 T 29-03-2018 THSYN_RS28250 dc81fd53d88d1d23bdf5372e7b2b929a 175 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 15 174 20.806 T 29-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 THSYN_RS28250 dc81fd53d88d1d23bdf5372e7b2b929a 175 Pfam PF04390 Lipopolysaccharide-assembly 48 169 1.1E-6 T 29-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 THSYN_RS00825 4c799dfd922e669b0d9af172262dba46 498 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 109 473 2.5E-83 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 THSYN_RS00825 4c799dfd922e669b0d9af172262dba46 498 SUPERFAMILY SSF51445 15 494 9.73E-158 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS00825 4c799dfd922e669b0d9af172262dba46 498 Gene3D G3DSA:3.20.20.80 11 495 1.2E-157 T 29-03-2018 THSYN_RS00825 4c799dfd922e669b0d9af172262dba46 498 Pfam PF02446 4-alpha-glucanotransferase 21 473 2.8E-143 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 THSYN_RS30190 29914018b7437d19518ccd02e8d1c15e 332 Gene3D G3DSA:1.10.10.60 273 325 1.2E-5 T 29-03-2018 THSYN_RS30190 29914018b7437d19518ccd02e8d1c15e 332 Pfam PF04754 Putative transposase, YhgA-like 24 188 1.3E-30 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS30360 29914018b7437d19518ccd02e8d1c15e 332 Gene3D G3DSA:1.10.10.60 273 325 1.2E-5 T 29-03-2018 THSYN_RS30360 29914018b7437d19518ccd02e8d1c15e 332 Pfam PF04754 Putative transposase, YhgA-like 24 188 1.3E-30 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS04230 63f9808d5f996544857732b08692bd21 388 SUPERFAMILY SSF54106 339 388 7.06E-5 T 29-03-2018 IPR018392 LysM domain THSYN_RS04230 63f9808d5f996544857732b08692bd21 388 Gene3D G3DSA:1.10.287.510 228 337 0.1 T 29-03-2018 THSYN_RS04230 63f9808d5f996544857732b08692bd21 388 Gene3D G3DSA:1.20.5.340 94 221 4.3E-6 T 29-03-2018 THSYN_RS04230 63f9808d5f996544857732b08692bd21 388 Pfam PF01476 LysM domain 340 388 1.3E-7 T 29-03-2018 IPR018392 LysM domain THSYN_RS04230 63f9808d5f996544857732b08692bd21 388 Gene3D G3DSA:3.10.350.10 338 388 2.7E-11 T 29-03-2018 THSYN_RS04230 63f9808d5f996544857732b08692bd21 388 SMART SM00257 339 388 5.2E-4 T 29-03-2018 IPR018392 LysM domain THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 Gene3D G3DSA:3.30.450.40 123 299 4.8E-31 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 SUPERFAMILY SSF55781 320 492 2.16E-38 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 Pfam PF01590 GAF domain 142 296 2.6E-15 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 SUPERFAMILY SSF55785 9 113 3.66E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 Pfam PF00360 Phytochrome region 338 492 9.1E-37 T 29-03-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 SMART SM00065 139 313 1.0E-4 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 SUPERFAMILY SSF55781 126 308 4.17E-48 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 Pfam PF08446 PAS fold 13 68 1.7E-8 T 29-03-2018 IPR013654 PAS fold-2 GO:0006355 THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 PRINTS PR01033 Phytochrome signature 457 475 3.6E-19 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 PRINTS PR01033 Phytochrome signature 423 442 3.6E-19 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 PRINTS PR01033 Phytochrome signature 335 355 3.6E-19 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 PRINTS PR01033 Phytochrome signature 154 173 3.6E-19 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 PRINTS PR01033 Phytochrome signature 237 258 3.6E-19 T 29-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 THSYN_RS21500 dd8eb1235d4407b0d1bbbfc667b76792 501 Gene3D G3DSA:3.30.450.20 1 113 9.6E-9 T 29-03-2018 THSYN_RS22675 521f4e2ee9e1a8e083095130d382db5e 112 Pfam PF04358 DsrC like protein 7 112 1.6E-45 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE THSYN_RS22675 521f4e2ee9e1a8e083095130d382db5e 112 Gene3D G3DSA:3.30.1420.10 5 42 3.9E-13 T 29-03-2018 THSYN_RS22675 521f4e2ee9e1a8e083095130d382db5e 112 Gene3D G3DSA:1.10.10.370 43 111 9.7E-35 T 29-03-2018 THSYN_RS22675 521f4e2ee9e1a8e083095130d382db5e 112 PIRSF PIRSF006223 5 112 5.8E-42 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE THSYN_RS22675 521f4e2ee9e1a8e083095130d382db5e 112 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 6 112 5.0E-50 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE THSYN_RS22675 521f4e2ee9e1a8e083095130d382db5e 112 SUPERFAMILY SSF69721 4 112 3.01E-41 T 29-03-2018 IPR025526 DsrC-like domain THSYN_RS16110 df8fb356d0eeffab405074ffb246448c 608 SUPERFAMILY SSF116726 321 394 9.02E-18 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS16110 df8fb356d0eeffab405074ffb246448c 608 Gene3D G3DSA:3.30.70.1450 310 396 1.9E-17 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS16110 df8fb356d0eeffab405074ffb246448c 608 SUPERFAMILY SSF116726 217 299 9.16E-10 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS16110 df8fb356d0eeffab405074ffb246448c 608 Pfam PF02080 TrkA-C domain 324 390 7.5E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS16110 df8fb356d0eeffab405074ffb246448c 608 Pfam PF02080 TrkA-C domain 231 298 1.3E-9 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS16110 df8fb356d0eeffab405074ffb246448c 608 Pfam PF03600 Citrate transporter 16 552 5.8E-52 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 THSYN_RS16110 df8fb356d0eeffab405074ffb246448c 608 Gene3D G3DSA:3.30.70.1450 230 304 1.1E-10 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THSYN_RS04235 cf0de6baf9c20ae12411cd544b4b120a 453 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 77 415 3.4E-37 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THSYN_RS04235 cf0de6baf9c20ae12411cd544b4b120a 453 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 106 120 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THSYN_RS04235 cf0de6baf9c20ae12411cd544b4b120a 453 SUPERFAMILY SSF53686 28 428 6.68E-106 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THSYN_RS04235 cf0de6baf9c20ae12411cd544b4b120a 453 Gene3D G3DSA:3.40.50.1100 219 427 7.1E-29 T 29-03-2018 THSYN_RS04235 cf0de6baf9c20ae12411cd544b4b120a 453 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 22 428 38.706 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THSYN_RS04235 cf0de6baf9c20ae12411cd544b4b120a 453 PIRSF PIRSF001413 10 434 8.7E-121 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THSYN_RS04235 cf0de6baf9c20ae12411cd544b4b120a 453 Gene3D G3DSA:3.40.50.1100 90 218 2.4E-22 T 29-03-2018 THSYN_RS04235 cf0de6baf9c20ae12411cd544b4b120a 453 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 14 430 2.4E-191 T 29-03-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THSYN_RS04235 cf0de6baf9c20ae12411cd544b4b120a 453 PIRSF PIRSF500824 2 437 3.9E-197 T 29-03-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THSYN_RS25095 95a7d773650460e3c7e696920bc2a020 349 Gene3D G3DSA:3.20.20.70 37 230 3.1E-19 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS25095 95a7d773650460e3c7e696920bc2a020 349 Pfam PF04055 Radical SAM superfamily 52 184 1.3E-12 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS25095 95a7d773650460e3c7e696920bc2a020 349 SUPERFAMILY SSF102114 44 302 1.83E-28 T 29-03-2018 THSYN_RS01745 fbeb68956490da06584e86ed0bdcd710 403 PIRSF PIRSF000139 8 402 1.2E-108 T 29-03-2018 THSYN_RS01745 fbeb68956490da06584e86ed0bdcd710 403 SUPERFAMILY SSF54862 21 118 3.35E-20 T 29-03-2018 THSYN_RS01745 fbeb68956490da06584e86ed0bdcd710 403 Pfam PF02754 Cysteine-rich domain 171 254 1.2E-8 T 29-03-2018 IPR004017 Cysteine-rich domain THSYN_RS01745 fbeb68956490da06584e86ed0bdcd710 403 Pfam PF02754 Cysteine-rich domain 302 385 1.5E-11 T 29-03-2018 IPR004017 Cysteine-rich domain THSYN_RS01745 fbeb68956490da06584e86ed0bdcd710 403 Gene3D G3DSA:3.30.70.20 11 35 0.021 T 29-03-2018 THSYN_RS01745 fbeb68956490da06584e86ed0bdcd710 403 Gene3D G3DSA:3.30.70.20 82 292 5.0E-5 T 29-03-2018 THSYN_RS01745 fbeb68956490da06584e86ed0bdcd710 403 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS01745 fbeb68956490da06584e86ed0bdcd710 403 Gene3D G3DSA:3.30.70.20 36 81 2.3E-9 T 29-03-2018 THSYN_RS01745 fbeb68956490da06584e86ed0bdcd710 403 Pfam PF12838 4Fe-4S dicluster domain 24 89 2.9E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS05935 0f06c0bba74359cce12a80ee7fbf7d2f 97 SMART SM00530 39 95 2.6E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS05935 0f06c0bba74359cce12a80ee7fbf7d2f 97 Gene3D G3DSA:1.10.260.40 24 97 3.6E-10 T 29-03-2018 THSYN_RS05935 0f06c0bba74359cce12a80ee7fbf7d2f 97 SUPERFAMILY SSF47413 26 96 5.35E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS05935 0f06c0bba74359cce12a80ee7fbf7d2f 97 Pfam PF13744 Helix-turn-helix domain 16 96 4.0E-19 T 29-03-2018 THSYN_RS29795 a8fd600d86b847acfeb594c3fbec4df9 476 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 364 372 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site THSYN_RS29795 a8fd600d86b847acfeb594c3fbec4df9 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 298 312 1.2E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 THSYN_RS29795 a8fd600d86b847acfeb594c3fbec4df9 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 364 372 1.2E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 THSYN_RS29795 a8fd600d86b847acfeb594c3fbec4df9 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 409 426 1.2E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 THSYN_RS29795 a8fd600d86b847acfeb594c3fbec4df9 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 434 446 1.2E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 THSYN_RS29795 a8fd600d86b847acfeb594c3fbec4df9 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 388 399 1.2E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 THSYN_RS29795 a8fd600d86b847acfeb594c3fbec4df9 476 SUPERFAMILY SSF51445 4 465 2.53E-155 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS29795 a8fd600d86b847acfeb594c3fbec4df9 476 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 13 27 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site THSYN_RS29795 a8fd600d86b847acfeb594c3fbec4df9 476 Pfam PF00232 Glycosyl hydrolase family 1 8 469 6.4E-128 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 THSYN_RS29795 a8fd600d86b847acfeb594c3fbec4df9 476 Gene3D G3DSA:3.20.20.80 1 473 8.0E-144 T 29-03-2018 THSYN_RS20940 bc43d1a2373a595e1e05c97d8b53e74f 195 Pfam PF06414 Zeta toxin 59 141 4.9E-5 T 29-03-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 THSYN_RS20940 bc43d1a2373a595e1e05c97d8b53e74f 195 Gene3D G3DSA:3.40.50.300 4 182 1.6E-9 T 29-03-2018 THSYN_RS20940 bc43d1a2373a595e1e05c97d8b53e74f 195 SUPERFAMILY SSF52540 7 142 2.54E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 SUPERFAMILY SSF49299 552 635 6.41E-24 T 29-03-2018 IPR000601 PKD domain THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 Gene3D G3DSA:2.60.120.260 638 781 1.3E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 SMART SM00710 242 264 1100.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 SMART SM00710 422 443 160.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 SMART SM00710 392 416 660.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 SMART SM00710 270 292 12.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 Pfam PF07602 Protein of unknown function (DUF1565) 34 75 1.4E-5 T 29-03-2018 IPR011459 Domain of unknown function DUF1565 THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 Gene3D G3DSA:2.160.20.10 18 549 3.7E-48 T 29-03-2018 IPR012334 Pectin lyase fold THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 SMART SM00089 557 636 1.6E-20 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 Pfam PF00801 PKD domain 562 623 1.1E-10 T 29-03-2018 IPR000601 PKD domain THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 Gene3D G3DSA:2.60.40.10 553 637 6.1E-22 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 SUPERFAMILY SSF51126 321 549 1.44E-44 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 SUPERFAMILY SSF51126 15 88 1.44E-44 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS19845 730029425bc744fe9e44f288d3af2404 785 SUPERFAMILY SSF51126 174 291 1.44E-44 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS29850 25713ec3348fac0377521d0755fbf16a 58 Pfam PF05532 CsbD-like 5 56 2.2E-12 T 29-03-2018 IPR008462 CsbD-like domain THSYN_RS29850 25713ec3348fac0377521d0755fbf16a 58 Gene3D G3DSA:1.10.1470.10 1 58 1.8E-12 T 29-03-2018 IPR008462 CsbD-like domain THSYN_RS29850 25713ec3348fac0377521d0755fbf16a 58 SUPERFAMILY SSF69047 1 57 7.19E-12 T 29-03-2018 IPR008462 CsbD-like domain THSYN_RS10890 be156c02e7c702a9afd4467361141f48 359 SUPERFAMILY SSF53659 3 357 4.03E-120 T 29-03-2018 THSYN_RS10890 be156c02e7c702a9afd4467361141f48 359 Gene3D G3DSA:3.40.718.10 2 359 5.9E-126 T 29-03-2018 THSYN_RS10890 be156c02e7c702a9afd4467361141f48 359 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 357 51.353 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 THSYN_RS10890 be156c02e7c702a9afd4467361141f48 359 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 THSYN_RS10890 be156c02e7c702a9afd4467361141f48 359 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 353 2.9E-133 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THSYN_RS10890 be156c02e7c702a9afd4467361141f48 359 SMART SM01329 4 353 1.2E-204 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THSYN_RS10890 be156c02e7c702a9afd4467361141f48 359 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 352 2.9E-148 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 THSYN_RS14345 ce968b1abe84aadc618f6d5cda7fe3b3 851 SUPERFAMILY SSF52540 429 523 3.13E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14345 ce968b1abe84aadc618f6d5cda7fe3b3 851 Gene3D G3DSA:3.40.50.300 423 566 7.0E-7 T 29-03-2018 THSYN_RS14345 ce968b1abe84aadc618f6d5cda7fe3b3 851 Pfam PF12770 CHAT domain 130 375 1.7E-18 T 29-03-2018 IPR024983 CHAT domain THSYN_RS14345 ce968b1abe84aadc618f6d5cda7fe3b3 851 Gene3D G3DSA:3.40.50.1460 172 385 9.1E-21 T 29-03-2018 THSYN_RS31780 2484c2357a6aec67906c1ba3492f78ba 1002 SUPERFAMILY SSF52540 10 24 4.03E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31780 2484c2357a6aec67906c1ba3492f78ba 1002 SUPERFAMILY SSF52540 88 288 4.03E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31780 2484c2357a6aec67906c1ba3492f78ba 1002 SUPERFAMILY SSF52540 485 585 5.72E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31780 2484c2357a6aec67906c1ba3492f78ba 1002 SUPERFAMILY SSF52540 88 129 5.72E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31780 2484c2357a6aec67906c1ba3492f78ba 1002 Pfam PF04851 Type III restriction enzyme, res subunit 11 258 5.9E-14 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS31780 2484c2357a6aec67906c1ba3492f78ba 1002 Gene3D G3DSA:3.40.50.300 7 271 1.9E-20 T 29-03-2018 THSYN_RS05905 3427127601ccfdc2248f026ff65fec97 256 Gene3D G3DSA:3.20.20.370 18 241 1.1E-42 T 29-03-2018 THSYN_RS05905 3427127601ccfdc2248f026ff65fec97 256 SUPERFAMILY SSF88713 25 208 3.34E-38 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS05905 3427127601ccfdc2248f026ff65fec97 256 Pfam PF01522 Polysaccharide deacetylase 61 195 5.1E-29 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 THSYN_RS22440 94a5e428b351f1c548ed71a6a16a96f2 145 SUPERFAMILY SSF54106 91 141 3.27E-6 T 29-03-2018 IPR018392 LysM domain THSYN_RS22440 94a5e428b351f1c548ed71a6a16a96f2 145 Pfam PF01476 LysM domain 93 141 1.9E-10 T 29-03-2018 IPR018392 LysM domain THSYN_RS22440 94a5e428b351f1c548ed71a6a16a96f2 145 Gene3D G3DSA:3.10.350.10 88 145 8.3E-15 T 29-03-2018 THSYN_RS22440 94a5e428b351f1c548ed71a6a16a96f2 145 Pfam PF04972 BON domain 18 82 1.3E-14 T 29-03-2018 IPR007055 BON domain THSYN_RS22440 94a5e428b351f1c548ed71a6a16a96f2 145 SMART SM00257 92 141 7.0E-10 T 29-03-2018 IPR018392 LysM domain THSYN_RS07870 18dd1ea283823a37b8dc0291d42a8ad6 477 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 476 37.858 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 THSYN_RS07870 18dd1ea283823a37b8dc0291d42a8ad6 477 SMART SM00845 328 475 1.7E-82 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 THSYN_RS07870 18dd1ea283823a37b8dc0291d42a8ad6 477 Pfam PF02637 GatB domain 329 475 1.1E-53 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 THSYN_RS07870 18dd1ea283823a37b8dc0291d42a8ad6 477 SUPERFAMILY SSF55931 4 296 8.5E-116 T 29-03-2018 THSYN_RS07870 18dd1ea283823a37b8dc0291d42a8ad6 477 Gene3D G3DSA:1.10.10.410 415 476 1.7E-26 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal THSYN_RS07870 18dd1ea283823a37b8dc0291d42a8ad6 477 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 2 475 6.0E-173 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 THSYN_RS07870 18dd1ea283823a37b8dc0291d42a8ad6 477 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 144 158 - T 29-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 THSYN_RS07870 18dd1ea283823a37b8dc0291d42a8ad6 477 SUPERFAMILY SSF89095 297 402 1.16E-34 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 THSYN_RS07870 18dd1ea283823a37b8dc0291d42a8ad6 477 Pfam PF02934 GatB/GatE catalytic domain 5 288 1.4E-108 T 29-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 THSYN_RS03665 f2115399c192bdac88291e419dff82eb 249 SUPERFAMILY SSF75217 94 246 2.49E-48 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases THSYN_RS03665 f2115399c192bdac88291e419dff82eb 249 SUPERFAMILY SSF55315 5 77 8.0E-15 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like THSYN_RS03665 f2115399c192bdac88291e419dff82eb 249 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 78 3.5E-14 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 THSYN_RS03665 f2115399c192bdac88291e419dff82eb 249 Pfam PF00588 SpoU rRNA Methylase family 99 239 7.3E-38 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 THSYN_RS03665 f2115399c192bdac88291e419dff82eb 249 SMART SM00967 6 82 3.5E-10 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 THSYN_RS03665 f2115399c192bdac88291e419dff82eb 249 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 4 246 41.77 T 29-03-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB THSYN_RS03665 f2115399c192bdac88291e419dff82eb 249 Gene3D G3DSA:3.40.1280.10 87 249 1.1E-44 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THSYN_RS03665 f2115399c192bdac88291e419dff82eb 249 Gene3D G3DSA:3.30.1330.30 3 77 1.2E-15 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like THSYN_RS03665 f2115399c192bdac88291e419dff82eb 249 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 7 245 1.9E-71 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 THSYN_RS13135 0e9086ebdef139160a10b811caafed9e 573 Pfam PF12186 Acyl-CoA dehydrogenase C terminal 465 559 2.6E-7 T 29-03-2018 IPR020964 Acyl-CoA dehydrogenase, C-terminal THSYN_RS13135 0e9086ebdef139160a10b811caafed9e 573 SUPERFAMILY SSF158494 446 559 7.19E-12 T 29-03-2018 IPR020964 Acyl-CoA dehydrogenase, C-terminal THSYN_RS13135 0e9086ebdef139160a10b811caafed9e 573 Gene3D G3DSA:1.10.540.10 27 170 1.5E-18 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 THSYN_RS13135 0e9086ebdef139160a10b811caafed9e 573 SUPERFAMILY SSF47203 388 456 2.42E-42 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THSYN_RS13135 0e9086ebdef139160a10b811caafed9e 573 SUPERFAMILY SSF47203 282 356 2.42E-42 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THSYN_RS13135 0e9086ebdef139160a10b811caafed9e 573 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 282 447 5.0E-29 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THSYN_RS13135 0e9086ebdef139160a10b811caafed9e 573 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 173 267 5.1E-22 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 THSYN_RS13135 0e9086ebdef139160a10b811caafed9e 573 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 54 168 1.6E-15 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 THSYN_RS13135 0e9086ebdef139160a10b811caafed9e 573 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 413 432 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THSYN_RS13135 0e9086ebdef139160a10b811caafed9e 573 Gene3D G3DSA:2.40.110.10 172 269 4.1E-23 T 29-03-2018 THSYN_RS13135 0e9086ebdef139160a10b811caafed9e 573 Gene3D G3DSA:1.20.140.10 270 455 3.6E-40 T 29-03-2018 THSYN_RS13135 0e9086ebdef139160a10b811caafed9e 573 Gene3D G3DSA:1.20.120.470 456 568 1.2E-25 T 29-03-2018 THSYN_RS13135 0e9086ebdef139160a10b811caafed9e 573 SUPERFAMILY SSF56645 49 274 7.2E-49 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THSYN_RS12905 e6cb28163484c43fd772b1d76af4f25e 288 Gene3D G3DSA:3.40.50.300 12 280 7.3E-6 T 29-03-2018 THSYN_RS12905 e6cb28163484c43fd772b1d76af4f25e 288 SUPERFAMILY SSF52540 145 199 2.3E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12905 e6cb28163484c43fd772b1d76af4f25e 288 SUPERFAMILY SSF52540 14 47 2.3E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00935 c1a760490e14cb9f0572d3db01e5456e 306 Pfam PF13182 Protein of unknown function (DUF4007) 10 297 3.4E-78 T 29-03-2018 IPR025248 Domain of unknown function DUF4007 THSYN_RS02790 0474067d004b7f42c16e0b01a86b466b 275 Gene3D G3DSA:3.60.110.10 1 273 1.9E-72 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THSYN_RS02790 0474067d004b7f42c16e0b01a86b466b 275 Pfam PF00795 Carbon-nitrogen hydrolase 5 255 1.6E-50 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THSYN_RS02790 0474067d004b7f42c16e0b01a86b466b 275 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 154 174 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site THSYN_RS02790 0474067d004b7f42c16e0b01a86b466b 275 SUPERFAMILY SSF56317 1 269 1.83E-77 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THSYN_RS10825 c76f4a1732805cd5c17d07fb21e41b49 321 TIGRFAM TIGR02933 nifM_nitrog: nitrogen fixation protein NifM 21 290 3.3E-60 T 29-03-2018 IPR014282 Nitrogen fixation protein NifM THSYN_RS10825 c76f4a1732805cd5c17d07fb21e41b49 321 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 197 217 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 THSYN_RS10825 c76f4a1732805cd5c17d07fb21e41b49 321 Gene3D G3DSA:3.10.50.40 143 282 9.2E-26 T 29-03-2018 THSYN_RS10825 c76f4a1732805cd5c17d07fb21e41b49 321 Gene3D G3DSA:1.10.4030.10 17 127 5.9E-4 T 29-03-2018 THSYN_RS10825 c76f4a1732805cd5c17d07fb21e41b49 321 SUPERFAMILY SSF54534 144 255 1.11E-20 T 29-03-2018 THSYN_RS10825 c76f4a1732805cd5c17d07fb21e41b49 321 Pfam PF00639 PPIC-type PPIASE domain 158 255 1.2E-17 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 THSYN_RS10825 c76f4a1732805cd5c17d07fb21e41b49 321 SUPERFAMILY SSF109998 36 180 4.32E-12 T 29-03-2018 IPR027304 Trigger factor/SurA domain THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 317 2.9E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 Gene3D G3DSA:3.30.390.30 323 456 2.6E-38 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 3.3E-74 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 3.3E-74 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 3.3E-74 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 3.3E-74 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.3E-74 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 3.3E-74 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 3.3E-74 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 3.3E-74 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 3.3E-74 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 4 448 2.2E-172 T 29-03-2018 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081|Reactome: R-HSA-2408550|Reactome: R-HSA-3299685|Reactome: R-HSA-499943|Reactome: R-HSA-5628897 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 446 1.3E-32 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 SUPERFAMILY SSF51905 1 364 1.6E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 SUPERFAMILY SSF55424 335 449 6.53E-34 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PIRSF PIRSF000350 1 449 2.1E-83 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 Gene3D G3DSA:3.40.50.720 165 322 2.0E-33 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 Gene3D G3DSA:3.50.50.60 2 164 3.5E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 1.0E-33 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 1.0E-33 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 1.0E-33 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.0E-33 T 29-03-2018 THSYN_RS17100 9b412fcf9e4bf89c3e19b3f0843f1196 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 1.0E-33 T 29-03-2018 THSYN_RS09155 e213614c9c5a15b3af93bb8971c4d80e 510 Pfam PF00266 Aminotransferase class-V 128 420 4.9E-29 T 29-03-2018 IPR000192 Aminotransferase class V domain THSYN_RS09155 e213614c9c5a15b3af93bb8971c4d80e 510 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 12 36 0.0012 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THSYN_RS09155 e213614c9c5a15b3af93bb8971c4d80e 510 SUPERFAMILY SSF53383 64 447 1.08E-53 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS09155 e213614c9c5a15b3af93bb8971c4d80e 510 SUPERFAMILY SSF53383 475 500 1.08E-53 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS09155 e213614c9c5a15b3af93bb8971c4d80e 510 Gene3D G3DSA:3.90.1150.10 364 508 2.8E-6 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS09155 e213614c9c5a15b3af93bb8971c4d80e 510 Gene3D G3DSA:3.40.640.10 108 363 8.8E-30 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS17940 fa38ed91f2ff32594ef620fd4df4f064 142 Gene3D G3DSA:3.40.630.30 2 130 3.4E-15 T 29-03-2018 THSYN_RS17940 fa38ed91f2ff32594ef620fd4df4f064 142 Pfam PF00583 Acetyltransferase (GNAT) family 33 112 1.0E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS17940 fa38ed91f2ff32594ef620fd4df4f064 142 SUPERFAMILY SSF55729 37 117 4.73E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS10505 2cabf704069abdb678cdf4d8c76f0520 185 Pfam PF05685 Putative restriction endonuclease 22 169 3.4E-32 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS10505 2cabf704069abdb678cdf4d8c76f0520 185 SUPERFAMILY SSF52980 9 160 2.04E-22 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS10505 2cabf704069abdb678cdf4d8c76f0520 185 Gene3D G3DSA:3.90.1570.10 4 183 1.1E-37 T 29-03-2018 THSYN_RS01190 bfc0daaede8e22bc0ab222e1eaef3785 332 Gene3D G3DSA:3.40.50.720 140 315 7.4E-35 T 29-03-2018 THSYN_RS01190 bfc0daaede8e22bc0ab222e1eaef3785 332 SUPERFAMILY SSF51735 118 299 5.38E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS01190 bfc0daaede8e22bc0ab222e1eaef3785 332 SMART SM00829 10 329 9.7E-39 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THSYN_RS01190 bfc0daaede8e22bc0ab222e1eaef3785 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 1.9E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THSYN_RS01190 bfc0daaede8e22bc0ab222e1eaef3785 332 Gene3D G3DSA:3.90.180.10 1 139 4.8E-40 T 29-03-2018 THSYN_RS01190 bfc0daaede8e22bc0ab222e1eaef3785 332 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 146 167 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 THSYN_RS01190 bfc0daaede8e22bc0ab222e1eaef3785 332 Pfam PF13602 Zinc-binding dehydrogenase 189 329 1.9E-30 T 29-03-2018 THSYN_RS01190 bfc0daaede8e22bc0ab222e1eaef3785 332 SUPERFAMILY SSF50129 1 150 7.3E-37 T 29-03-2018 IPR011032 GroES-like THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 SUPERFAMILY SSF158472 204 254 9.81E-8 T 29-03-2018 THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 Pfam PF00672 HAMP domain 203 252 3.2E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 474 2.5E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 Gene3D G3DSA:3.30.565.10 328 482 1.1E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 SUPERFAMILY SSF55874 312 473 4.58E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 456 7.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 7.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 433 7.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 SMART SM00304 203 256 6.3E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 SMART SM00388 257 323 1.3E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 SUPERFAMILY SSF47384 240 323 2.75E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 Gene3D G3DSA:1.10.287.130 247 319 1.7E-8 T 29-03-2018 THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 SMART SM00387 368 477 8.0E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08195 75b2e07cb054e69b69b69f4bce277c6e 482 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 323 1.9E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS11575 61e0a62134065c17404f3d1f66de2e5f 487 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 139 363 5.4E-37 T 29-03-2018 IPR000477 Reverse transcriptase domain THSYN_RS11575 61e0a62134065c17404f3d1f66de2e5f 487 SUPERFAMILY SSF56672 33 392 5.44E-53 T 29-03-2018 THSYN_RS11575 61e0a62134065c17404f3d1f66de2e5f 487 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 86 448 3.1E-102 T 29-03-2018 IPR030931 Group II intron reverse transcriptase/maturase THSYN_RS11575 61e0a62134065c17404f3d1f66de2e5f 487 Pfam PF08388 Group II intron, maturase-specific domain 388 451 1.9E-4 T 29-03-2018 IPR013597 Group II intron, maturase-specific THSYN_RS11575 61e0a62134065c17404f3d1f66de2e5f 487 Gene3D G3DSA:3.30.70.270 170 363 1.3E-27 T 29-03-2018 THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 523 1.7E-98 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 Hamap MF_00600 60 kDa chaperonin [groL]. 2 548 41.954 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 Gene3D G3DSA:1.10.560.10 1 185 1.4E-43 T 29-03-2018 IPR027413 GroEL-like equatorial domain THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 SUPERFAMILY SSF54849 137 205 1.05E-25 T 29-03-2018 THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 PRINTS PR00298 60kDa chaperonin signature 268 291 7.4E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 PRINTS PR00298 60kDa chaperonin signature 398 419 7.4E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 PRINTS PR00298 60kDa chaperonin signature 83 110 7.4E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 PRINTS PR00298 60kDa chaperonin signature 350 375 7.4E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 PRINTS PR00298 60kDa chaperonin signature 27 53 7.4E-75 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 SUPERFAMILY SSF52029 184 376 2.09E-84 T 29-03-2018 IPR027409 GroEL-like apical domain THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 Gene3D G3DSA:1.10.560.10 374 516 4.3E-24 T 29-03-2018 IPR027413 GroEL-like equatorial domain THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 Gene3D G3DSA:3.50.7.10 186 373 4.7E-100 T 29-03-2018 IPR027409 GroEL-like apical domain THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 1.7E-259 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 SUPERFAMILY SSF48592 406 521 1.3E-76 T 29-03-2018 THSYN_RS26290 0f3ed7f84d9a8de84a9539e9cbde71cc 553 SUPERFAMILY SSF48592 7 134 1.3E-76 T 29-03-2018 THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 SUPERFAMILY SSF141868 473 717 1.27E-91 T 29-03-2018 IPR001633 EAL domain THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 SUPERFAMILY SSF55785 182 290 1.48E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 SUPERFAMILY SSF55073 297 460 1.88E-46 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 SMART SM00091 171 234 12.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 SMART SM00091 48 114 1.5E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 Pfam PF08448 PAS fold 55 162 2.9E-10 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 Pfam PF08448 PAS fold 177 282 5.9E-7 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 Gene3D G3DSA:3.30.450.20 163 195 0.097 T 29-03-2018 THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 49 164 9.2E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 170 287 2.2E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 Pfam PF00990 Diguanylate cyclase, GGDEF domain 292 454 7.1E-47 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 SUPERFAMILY SSF55785 59 165 2.88E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 Gene3D G3DSA:3.30.450.20 196 287 1.3E-15 T 29-03-2018 THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 SMART SM00052 468 714 1.1E-124 T 29-03-2018 IPR001633 EAL domain THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 SMART SM00086 119 160 8.6 T 29-03-2018 IPR001610 PAC motif THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 SMART SM00086 240 281 0.098 T 29-03-2018 IPR001610 PAC motif THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 Gene3D G3DSA:3.30.450.20 1 162 6.1E-18 T 29-03-2018 THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 Pfam PF00563 EAL domain 474 709 1.5E-74 T 29-03-2018 IPR001633 EAL domain THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 Gene3D G3DSA:3.20.20.450 459 717 2.6E-105 T 29-03-2018 IPR001633 EAL domain THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 288 457 1.8E-43 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 SMART SM00267 281 458 6.8E-60 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS19985 fae23abc1c949e39ee5d82a7c0f3bf0d 719 Gene3D G3DSA:3.30.70.270 288 458 1.3E-58 T 29-03-2018 THSYN_RS14225 239ad214c6f1421429e0d4d7cf762d33 395 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 48 378 2.7E-76 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS14225 239ad214c6f1421429e0d4d7cf762d33 395 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 58 297 3.8E-8 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS14225 239ad214c6f1421429e0d4d7cf762d33 395 Gene3D G3DSA:1.20.1600.10 52 343 7.7E-24 T 29-03-2018 THSYN_RS14225 239ad214c6f1421429e0d4d7cf762d33 395 SUPERFAMILY SSF111369 61 303 4.18E-61 T 29-03-2018 THSYN_RS29070 a668d64ea3b1df79fc503b22b8fdb2e6 297 Pfam PF01061 ABC-2 type transporter 47 257 2.1E-28 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 Pfam PF00459 Inositol monophosphatase family 3 253 2.9E-68 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 SUPERFAMILY SSF56655 2 259 4.19E-86 T 29-03-2018 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 Gene3D G3DSA:3.40.190.80 144 264 1.2E-35 T 29-03-2018 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 209 223 - T 29-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 PRINTS PR01959 SuhB family inositol monophosphatase signature 102 121 3.7E-31 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 PRINTS PR01959 SuhB family inositol monophosphatase signature 154 180 3.7E-31 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 PRINTS PR01959 SuhB family inositol monophosphatase signature 196 208 3.7E-31 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 3.7E-31 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 Gene3D G3DSA:3.30.540.10 1 143 1.2E-46 T 29-03-2018 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 5.4E-59 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 5.4E-59 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 175 196 5.4E-59 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 206 230 5.4E-59 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 128 151 5.4E-59 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 79 95 5.4E-59 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS26595 97bbf9c8425dcfead3c6a7f5cf034be0 265 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 79 92 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site THSYN_RS13650 31314625ef16a997ad337c9a8800c994 178 Pfam PF12019 Type II transport protein GspH 39 158 2.6E-14 T 29-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THSYN_RS13650 31314625ef16a997ad337c9a8800c994 178 Gene3D G3DSA:3.30.700.10 5 155 2.9E-8 T 29-03-2018 THSYN_RS13650 31314625ef16a997ad337c9a8800c994 178 SUPERFAMILY SSF54523 5 94 3.85E-12 T 29-03-2018 THSYN_RS24050 9e4ae2d58b32b8b5e15468f3cdea0583 254 TIGRFAM TIGR00613 reco: DNA repair protein RecO 11 234 6.4E-22 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 THSYN_RS24050 9e4ae2d58b32b8b5e15468f3cdea0583 254 Pfam PF11967 Recombination protein O N terminal 11 79 1.3E-13 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal THSYN_RS24050 9e4ae2d58b32b8b5e15468f3cdea0583 254 SUPERFAMILY SSF57863 92 182 8.11E-10 T 29-03-2018 THSYN_RS24050 9e4ae2d58b32b8b5e15468f3cdea0583 254 Hamap MF_00201 DNA repair protein RecO [recO]. 6 236 21.416 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 THSYN_RS24050 9e4ae2d58b32b8b5e15468f3cdea0583 254 Gene3D G3DSA:2.40.50.140 10 81 1.8E-15 T 29-03-2018 THSYN_RS24050 9e4ae2d58b32b8b5e15468f3cdea0583 254 Pfam PF02565 Recombination protein O C terminal 90 231 1.0E-20 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 THSYN_RS24050 9e4ae2d58b32b8b5e15468f3cdea0583 254 SUPERFAMILY SSF50249 10 80 4.11E-11 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS28565 050ca8b4003e9f9797ccd24e77a5c246 371 Pfam PF01702 Queuine tRNA-ribosyltransferase 126 359 2.9E-86 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THSYN_RS28565 050ca8b4003e9f9797ccd24e77a5c246 371 SUPERFAMILY SSF51713 1 360 5.36E-155 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THSYN_RS28565 050ca8b4003e9f9797ccd24e77a5c246 371 Gene3D G3DSA:3.20.20.105 1 367 1.5E-151 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THSYN_RS28565 050ca8b4003e9f9797ccd24e77a5c246 371 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 3 361 2.1E-160 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THSYN_RS28565 050ca8b4003e9f9797ccd24e77a5c246 371 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 3 361 1.1E-153 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THSYN_RS28565 050ca8b4003e9f9797ccd24e77a5c246 371 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 362 54.66 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THSYN_RS08070 01d04cc59edeacc8e86fca12436d0817 128 Pfam PF12616 Protein of unknown function (DUF3775) 53 124 5.8E-27 T 29-03-2018 IPR022254 Protein of unknown function DUF3775 THSYN_RS24995 efbc61e3a4bd6b322e5ac0087a4bb2b5 410 Pfam PF13579 Glycosyl transferase 4-like domain 22 200 1.2E-20 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS24995 efbc61e3a4bd6b322e5ac0087a4bb2b5 410 Gene3D G3DSA:3.40.50.2000 215 388 9.5E-30 T 29-03-2018 THSYN_RS24995 efbc61e3a4bd6b322e5ac0087a4bb2b5 410 SUPERFAMILY SSF53756 3 403 1.47E-53 T 29-03-2018 THSYN_RS24995 efbc61e3a4bd6b322e5ac0087a4bb2b5 410 Gene3D G3DSA:3.40.50.2000 19 214 3.6E-20 T 29-03-2018 THSYN_RS24995 efbc61e3a4bd6b322e5ac0087a4bb2b5 410 Pfam PF00534 Glycosyl transferases group 1 223 380 5.9E-15 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS10595 5aa0fc1b5bab470783b9be3fbb17aa2f 448 SUPERFAMILY SSF102114 124 372 4.32E-58 T 29-03-2018 THSYN_RS10595 5aa0fc1b5bab470783b9be3fbb17aa2f 448 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 437 6.5E-139 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 THSYN_RS10595 5aa0fc1b5bab470783b9be3fbb17aa2f 448 Pfam PF01938 TRAM domain 379 439 6.7E-19 T 29-03-2018 IPR002792 TRAM domain THSYN_RS10595 5aa0fc1b5bab470783b9be3fbb17aa2f 448 Gene3D G3DSA:3.80.30.20 144 381 1.7E-49 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe THSYN_RS10595 5aa0fc1b5bab470783b9be3fbb17aa2f 448 Pfam PF00919 Uncharacterized protein family UPF0004 4 104 8.7E-26 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 THSYN_RS10595 5aa0fc1b5bab470783b9be3fbb17aa2f 448 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 438 2.2E-173 T 29-03-2018 THSYN_RS10595 5aa0fc1b5bab470783b9be3fbb17aa2f 448 SMART SM00729 147 367 1.3E-53 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS10595 5aa0fc1b5bab470783b9be3fbb17aa2f 448 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 THSYN_RS10595 5aa0fc1b5bab470783b9be3fbb17aa2f 448 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 440 71.177 T 29-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 THSYN_RS10595 5aa0fc1b5bab470783b9be3fbb17aa2f 448 Pfam PF04055 Radical SAM superfamily 151 325 5.0E-25 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 SMART SM00065 413 567 3.7E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 SUPERFAMILY SSF55073 582 740 1.65E-47 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 SMART SM00267 566 738 1.4E-56 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 Pfam PF13185 GAF domain 413 558 1.3E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 SUPERFAMILY SSF55781 415 559 1.5E-18 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 SMART SM00052 748 994 9.0E-80 T 29-03-2018 IPR001633 EAL domain THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 Gene3D G3DSA:3.30.450.40 391 574 2.3E-20 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 Gene3D G3DSA:3.30.450.20 237 390 7.1E-28 T 29-03-2018 THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 Pfam PF08447 PAS fold 287 375 4.5E-18 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 SUPERFAMILY SSF141868 755 1007 1.7E-76 T 29-03-2018 IPR001633 EAL domain THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 261 389 1.3E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 574 736 2.0E-38 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 SMART SM00086 339 382 2.7E-5 T 29-03-2018 IPR001610 PAC motif THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 Gene3D G3DSA:3.20.20.450 741 996 2.3E-85 T 29-03-2018 IPR001633 EAL domain THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 Pfam PF00563 EAL domain 755 989 3.8E-65 T 29-03-2018 IPR001633 EAL domain THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 Pfam PF00990 Diguanylate cyclase, GGDEF domain 577 734 9.1E-44 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 Gene3D G3DSA:3.30.70.270 575 740 6.8E-58 T 29-03-2018 THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 SUPERFAMILY SSF55785 272 385 4.51E-18 T 29-03-2018 IPR000014 PAS domain THSYN_RS01105 cb8df1a5132e29c4a3cac7f8ed2b0b94 1137 SMART SM00091 264 332 0.0063 T 29-03-2018 IPR000014 PAS domain THSYN_RS29940 75f5838e53991914e4d1a2653ad30ad0 2018 SUPERFAMILY SSF52540 1331 1578 1.76E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29940 75f5838e53991914e4d1a2653ad30ad0 2018 Gene3D G3DSA:3.40.50.300 1335 1490 1.1E-5 T 29-03-2018 THSYN_RS03060 24106d479a981181099c7d40dd8c0233 397 SUPERFAMILY SSF111369 56 293 1.06E-5 T 29-03-2018 THSYN_RS03060 24106d479a981181099c7d40dd8c0233 397 Gene3D G3DSA:2.40.50.100 64 149 2.9E-11 T 29-03-2018 THSYN_RS03060 24106d479a981181099c7d40dd8c0233 397 Gene3D G3DSA:2.40.50.100 193 374 7.2E-5 T 29-03-2018 THSYN_RS03060 24106d479a981181099c7d40dd8c0233 397 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 288 2.2E-12 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS03060 24106d479a981181099c7d40dd8c0233 397 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 39 388 1.4E-37 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS30265 d41f58149647414ad8d3739f9f91725d 359 Pfam PF10123 Mu-like prophage I protein 22 318 1.4E-67 T 29-03-2018 IPR012106 Protease, Mu phage/prophage I type THSYN_RS30265 d41f58149647414ad8d3739f9f91725d 359 PIRSF PIRSF016624 6 343 1.2E-54 T 29-03-2018 IPR012106 Protease, Mu phage/prophage I type THSYN_RS12005 ba8712441b286564decd6dbfa1311e44 118 Pfam PF01927 Mut7-C RNAse domain 2 57 8.0E-7 T 29-03-2018 IPR002782 Mut7-C RNAse domain THSYN_RS01635 43437f24d72418afbff178a7d8e5b937 143 Pfam PF01850 PIN domain 4 133 7.3E-12 T 29-03-2018 IPR002716 PIN domain THSYN_RS01635 43437f24d72418afbff178a7d8e5b937 143 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 139 10.393 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS01635 43437f24d72418afbff178a7d8e5b937 143 SUPERFAMILY SSF88723 4 138 8.83E-13 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS01635 43437f24d72418afbff178a7d8e5b937 143 Gene3D G3DSA:3.40.50.1010 2 143 1.7E-17 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS24110 0cc7980df202b60aeda45f425e43859b 94 SUPERFAMILY SSF81593 11 70 1.37E-10 T 29-03-2018 THSYN_RS24110 0cc7980df202b60aeda45f425e43859b 94 Gene3D G3DSA:1.20.120.330 1 77 3.6E-13 T 29-03-2018 THSYN_RS24110 0cc7980df202b60aeda45f425e43859b 94 Pfam PF05168 HEPN domain 9 72 4.3E-14 T 29-03-2018 IPR007842 HEPN domain THSYN_RS26635 08c49d08e4e32c97dd3ea82f4ddb68fd 796 Gene3D G3DSA:3.40.50.10140 451 587 4.2E-16 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS26635 08c49d08e4e32c97dd3ea82f4ddb68fd 796 Pfam PF13676 TIR domain 463 561 1.1E-16 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS26635 08c49d08e4e32c97dd3ea82f4ddb68fd 796 SUPERFAMILY SSF52200 453 572 6.54E-16 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS26635 08c49d08e4e32c97dd3ea82f4ddb68fd 796 SUPERFAMILY SSF52540 205 334 2.88E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26635 08c49d08e4e32c97dd3ea82f4ddb68fd 796 SUPERFAMILY SSF52540 68 126 2.88E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26635 08c49d08e4e32c97dd3ea82f4ddb68fd 796 Gene3D G3DSA:3.40.50.300 61 268 0.0018 T 29-03-2018 THSYN_RS21965 273259029e6e3da69387a800eb62d5bb 81 Gene3D G3DSA:2.10.260.10 5 42 2.0E-8 T 29-03-2018 THSYN_RS21965 273259029e6e3da69387a800eb62d5bb 81 SUPERFAMILY SSF89447 4 63 1.05E-10 T 29-03-2018 THSYN_RS21965 273259029e6e3da69387a800eb62d5bb 81 SMART SM00966 8 48 1.4E-5 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS21965 273259029e6e3da69387a800eb62d5bb 81 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 53 1.2E-11 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS27045 ff0e249dce1e22645ab253165115afb4 191 Gene3D G3DSA:3.90.80.10 30 140 1.4E-11 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THSYN_RS27045 ff0e249dce1e22645ab253165115afb4 191 Pfam PF00719 Inorganic pyrophosphatase 43 126 5.9E-8 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THSYN_RS27045 ff0e249dce1e22645ab253165115afb4 191 SUPERFAMILY SSF50324 39 148 2.35E-22 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THSYN_RS14365 184207d9c640191804f94cb116e1dd99 807 SUPERFAMILY SSF52200 8 157 3.01E-16 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS14365 184207d9c640191804f94cb116e1dd99 807 Gene3D G3DSA:1.25.40.10 680 801 5.0E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14365 184207d9c640191804f94cb116e1dd99 807 SUPERFAMILY SSF52540 202 428 1.57E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14365 184207d9c640191804f94cb116e1dd99 807 Gene3D G3DSA:3.40.50.10140 4 156 4.8E-15 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS14365 184207d9c640191804f94cb116e1dd99 807 SUPERFAMILY SSF48452 672 787 9.87E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14365 184207d9c640191804f94cb116e1dd99 807 SMART SM00255 9 290 6.0E-4 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS14365 184207d9c640191804f94cb116e1dd99 807 Gene3D G3DSA:3.40.50.300 187 363 2.6E-10 T 29-03-2018 THSYN_RS14365 184207d9c640191804f94cb116e1dd99 807 Pfam PF13676 TIR domain 13 114 3.5E-15 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS14365 184207d9c640191804f94cb116e1dd99 807 Pfam PF13191 AAA ATPase domain 203 337 8.8E-8 T 29-03-2018 THSYN_RS04310 446110749248535ec92b3cf711069e10 959 Gene3D G3DSA:3.40.50.300 184 369 5.0E-9 T 29-03-2018 THSYN_RS04310 446110749248535ec92b3cf711069e10 959 SUPERFAMILY SSF52200 6 124 5.36E-5 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS04310 446110749248535ec92b3cf711069e10 959 Gene3D G3DSA:3.40.50.10140 3 151 2.6E-12 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS04310 446110749248535ec92b3cf711069e10 959 Pfam PF08357 SEFIR domain 6 134 2.4E-12 T 29-03-2018 IPR013568 SEFIR domain THSYN_RS04310 446110749248535ec92b3cf711069e10 959 SUPERFAMILY SSF52540 196 441 1.39E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04310 446110749248535ec92b3cf711069e10 959 SUPERFAMILY SSF48452 717 849 1.55E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS04310 446110749248535ec92b3cf711069e10 959 Gene3D G3DSA:1.25.40.10 370 890 7.9E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16865 088e6457b2fe5b467f67443a1d5d8b3f 74 Pfam PF03884 DNA gyrase inhibitor YacG 13 62 3.3E-23 T 29-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 THSYN_RS16865 088e6457b2fe5b467f67443a1d5d8b3f 74 Gene3D G3DSA:3.30.50.10 9 66 9.5E-25 T 29-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 THSYN_RS16865 088e6457b2fe5b467f67443a1d5d8b3f 74 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 9 66 19.202 T 29-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 THSYN_RS16865 088e6457b2fe5b467f67443a1d5d8b3f 74 SUPERFAMILY SSF57716 9 65 2.57E-19 T 29-03-2018 THSYN_RS30995 5de94d669ef8dc4c9e1604dc30f46c84 183 Gene3D G3DSA:3.50.20.10 44 180 1.2E-32 T 29-03-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THSYN_RS30995 5de94d669ef8dc4c9e1604dc30f46c84 183 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 5 138 1.5E-34 T 29-03-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THSYN_RS30995 5de94d669ef8dc4c9e1604dc30f46c84 183 Gene3D G3DSA:3.30.60.30 2 42 5.5E-15 T 29-03-2018 THSYN_RS30995 5de94d669ef8dc4c9e1604dc30f46c84 183 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 5 141 2.0E-31 T 29-03-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THSYN_RS30995 5de94d669ef8dc4c9e1604dc30f46c84 183 SUPERFAMILY SSF56271 4 162 2.62E-42 T 29-03-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THSYN_RS30995 5de94d669ef8dc4c9e1604dc30f46c84 183 PIRSF PIRSF005216 1 182 1.8E-55 T 29-03-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THSYN_RS30995 5de94d669ef8dc4c9e1604dc30f46c84 183 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 183 76.008 T 29-03-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THSYN_RS30995 5de94d669ef8dc4c9e1604dc30f46c84 183 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 4 181 4.2E-56 T 29-03-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THSYN_RS00265 fd4d79b368976990902a7a5bb56ccc15 206 Pfam PF05685 Putative restriction endonuclease 32 198 2.3E-28 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS00265 fd4d79b368976990902a7a5bb56ccc15 206 Gene3D G3DSA:3.90.1570.10 19 202 9.8E-33 T 29-03-2018 THSYN_RS00265 fd4d79b368976990902a7a5bb56ccc15 206 SUPERFAMILY SSF52980 23 202 1.02E-30 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS26435 b9775ce1670e2cb6076098d4c136ca33 279 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 279 145.919 T 29-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 THSYN_RS26435 b9775ce1670e2cb6076098d4c136ca33 279 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 7 271 4.5E-135 T 29-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 THSYN_RS26435 b9775ce1670e2cb6076098d4c136ca33 279 Pfam PF02675 S-adenosylmethionine decarboxylase 37 179 6.1E-31 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 THSYN_RS26435 b9775ce1670e2cb6076098d4c136ca33 279 SUPERFAMILY SSF56276 122 184 1.02E-22 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 THSYN_RS26435 b9775ce1670e2cb6076098d4c136ca33 279 SUPERFAMILY SSF56276 47 88 1.02E-22 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 THSYN_RS26435 b9775ce1670e2cb6076098d4c136ca33 279 Gene3D G3DSA:3.60.90.10 32 199 2.2E-44 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 THSYN_RS26435 b9775ce1670e2cb6076098d4c136ca33 279 PIRSF PIRSF001356 3 273 2.0E-134 T 29-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 THSYN_RS29445 c808bede7b501815577c6868720dea58 695 Pfam PF11412 Disulphide bond corrector protein DsbC 28 146 1.3E-18 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THSYN_RS29445 c808bede7b501815577c6868720dea58 695 Gene3D G3DSA:2.60.40.1250 30 154 1.5E-7 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THSYN_RS29445 c808bede7b501815577c6868720dea58 695 SUPERFAMILY SSF52833 584 675 7.16E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS29445 c808bede7b501815577c6868720dea58 695 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 293 471 2.8E-11 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 THSYN_RS29445 c808bede7b501815577c6868720dea58 695 Pfam PF13899 Thioredoxin-like 584 666 2.0E-15 T 29-03-2018 THSYN_RS29445 c808bede7b501815577c6868720dea58 695 Gene3D G3DSA:3.40.30.10 560 676 1.3E-6 T 29-03-2018 THSYN_RS26325 242d28c78a654837d4155d6c55ed7df3 390 Gene3D G3DSA:3.40.50.300 5 140 1.4E-10 T 29-03-2018 THSYN_RS26325 242d28c78a654837d4155d6c55ed7df3 390 Pfam PF13173 AAA domain 19 140 1.4E-22 T 29-03-2018 THSYN_RS26325 242d28c78a654837d4155d6c55ed7df3 390 Pfam PF13635 Domain of unknown function (DUF4143) 181 337 6.5E-24 T 29-03-2018 IPR025420 Domain of unknown function DUF4143 THSYN_RS26325 242d28c78a654837d4155d6c55ed7df3 390 SUPERFAMILY SSF46785 194 248 1.3E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26325 242d28c78a654837d4155d6c55ed7df3 390 SUPERFAMILY SSF52540 17 184 4.89E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26325 242d28c78a654837d4155d6c55ed7df3 390 Gene3D G3DSA:1.10.10.10 191 258 8.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26325 242d28c78a654837d4155d6c55ed7df3 390 SMART SM00382 17 138 2.3E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS20945 30f6537f9b5fe748d8a19316ab304f17 394 Pfam PF01420 Type I restriction modification DNA specificity domain 20 171 3.1E-9 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS20945 30f6537f9b5fe748d8a19316ab304f17 394 Pfam PF01420 Type I restriction modification DNA specificity domain 258 371 1.2E-6 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS20945 30f6537f9b5fe748d8a19316ab304f17 394 SUPERFAMILY SSF116734 188 392 7.85E-35 T 29-03-2018 THSYN_RS20945 30f6537f9b5fe748d8a19316ab304f17 394 Gene3D G3DSA:1.10.287.1120 359 393 1.7E-9 T 29-03-2018 THSYN_RS20945 30f6537f9b5fe748d8a19316ab304f17 394 SUPERFAMILY SSF116734 12 188 3.92E-31 T 29-03-2018 THSYN_RS20945 30f6537f9b5fe748d8a19316ab304f17 394 Gene3D G3DSA:3.90.220.20 171 358 3.4E-29 T 29-03-2018 THSYN_RS20945 30f6537f9b5fe748d8a19316ab304f17 394 Gene3D G3DSA:3.90.220.20 5 170 4.2E-18 T 29-03-2018 THSYN_RS24560 adf94076def273849dccd5444f59c2b7 370 Pfam PF06804 NlpB/DapX lipoprotein 17 367 1.4E-35 T 29-03-2018 IPR010653 NlpB/DapX lipoprotein THSYN_RS23465 c58451b6e47e06ae36ead9626086a95d 162 Pfam PF04093 rod shape-determining protein MreD 11 153 1.6E-24 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 THSYN_RS23465 c58451b6e47e06ae36ead9626086a95d 162 PIRSF PIRSF018472 5 161 1.3E-48 T 29-03-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type THSYN_RS23465 c58451b6e47e06ae36ead9626086a95d 162 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 11 153 1.7E-33 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 THSYN_RS02185 471cf70e4db4fbaa1bea304cb0ac20b8 475 Gene3D G3DSA:3.40.50.150 26 213 4.6E-20 T 29-03-2018 THSYN_RS02185 471cf70e4db4fbaa1bea304cb0ac20b8 475 SUPERFAMILY SSF53448 240 474 1.13E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS02185 471cf70e4db4fbaa1bea304cb0ac20b8 475 SUPERFAMILY SSF53335 3 194 1.61E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02185 471cf70e4db4fbaa1bea304cb0ac20b8 475 Pfam PF13649 Methyltransferase domain 51 133 5.2E-12 T 29-03-2018 THSYN_RS02185 471cf70e4db4fbaa1bea304cb0ac20b8 475 Gene3D G3DSA:3.90.550.10 214 473 1.8E-29 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS02185 471cf70e4db4fbaa1bea304cb0ac20b8 475 Pfam PF00535 Glycosyl transferase family 2 241 371 2.7E-18 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS32840 691501cae6f1af525ea4731bc887e767 167 Gene3D G3DSA:3.10.450.40 9 157 4.0E-24 T 29-03-2018 THSYN_RS32840 691501cae6f1af525ea4731bc887e767 167 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 11 161 1.5E-26 T 29-03-2018 IPR017737 Type VI secretion system, lysozyme-related protein THSYN_RS32840 691501cae6f1af525ea4731bc887e767 167 Pfam PF04965 Gene 25-like lysozyme 39 142 2.6E-22 T 29-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD THSYN_RS32840 691501cae6f1af525ea4731bc887e767 167 SUPERFAMILY SSF160719 37 152 2.09E-8 T 29-03-2018 THSYN_RS20040 5f39a5f8e317d21ca1691f9d1b574152 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 2.4E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS20040 5f39a5f8e317d21ca1691f9d1b574152 227 SUPERFAMILY SSF52172 1 170 6.34E-38 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS20040 5f39a5f8e317d21ca1691f9d1b574152 227 Pfam PF00072 Response regulator receiver domain 4 112 4.2E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS20040 5f39a5f8e317d21ca1691f9d1b574152 227 SMART SM00448 1 112 8.7E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS20040 5f39a5f8e317d21ca1691f9d1b574152 227 Gene3D G3DSA:1.10.10.10 109 226 1.3E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS20040 5f39a5f8e317d21ca1691f9d1b574152 227 Gene3D G3DSA:3.40.50.2300 1 108 6.0E-33 T 29-03-2018 THSYN_RS20040 5f39a5f8e317d21ca1691f9d1b574152 227 SMART SM00862 145 220 7.0E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS17815 07d626a6c3c3d20dbeea67d421985033 186 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 13 142 3.2E-36 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THSYN_RS17815 07d626a6c3c3d20dbeea67d421985033 186 SUPERFAMILY SSF55083 11 161 2.22E-50 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THSYN_RS17815 07d626a6c3c3d20dbeea67d421985033 186 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 12 142 7.9E-41 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THSYN_RS17815 07d626a6c3c3d20dbeea67d421985033 186 Gene3D G3DSA:3.30.70.560 9 176 2.1E-53 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THSYN_RS17815 07d626a6c3c3d20dbeea67d421985033 186 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 97 108 - T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THSYN_RS15545 ebc52fbc92bfc2fedc533c94256b8ab7 1184 Pfam PF00149 Calcineurin-like phosphoesterase 11 256 1.1E-10 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS15545 ebc52fbc92bfc2fedc533c94256b8ab7 1184 SUPERFAMILY SSF56300 7 110 6.91E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS15545 ebc52fbc92bfc2fedc533c94256b8ab7 1184 SUPERFAMILY SSF56300 144 293 6.91E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS15545 ebc52fbc92bfc2fedc533c94256b8ab7 1184 Pfam PF03781 Sulfatase-modifying factor enzyme 1 911 1177 2.0E-51 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS15545 ebc52fbc92bfc2fedc533c94256b8ab7 1184 SUPERFAMILY SSF56436 911 1178 4.24E-63 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS15545 ebc52fbc92bfc2fedc533c94256b8ab7 1184 Gene3D G3DSA:3.60.21.10 1 320 2.4E-22 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS15545 ebc52fbc92bfc2fedc533c94256b8ab7 1184 SUPERFAMILY SSF52540 511 643 1.22E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15545 ebc52fbc92bfc2fedc533c94256b8ab7 1184 SUPERFAMILY SSF52540 420 453 1.22E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15545 ebc52fbc92bfc2fedc533c94256b8ab7 1184 Gene3D G3DSA:3.90.1580.10 899 1184 3.8E-64 T 29-03-2018 THSYN_RS15545 ebc52fbc92bfc2fedc533c94256b8ab7 1184 Gene3D G3DSA:3.40.50.300 408 578 1.1E-9 T 29-03-2018 THSYN_RS07890 870aab670aa4b369b31eab420d4e5479 503 Pfam PF00483 Nucleotidyl transferase 5 315 1.1E-56 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THSYN_RS07890 870aab670aa4b369b31eab420d4e5479 503 Pfam PF01050 Mannose-6-phosphate isomerase 344 494 3.7E-71 T 29-03-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 THSYN_RS07890 870aab670aa4b369b31eab420d4e5479 503 Gene3D G3DSA:3.90.550.10 2 366 2.7E-89 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS07890 870aab670aa4b369b31eab420d4e5479 503 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 497 1.2E-197 T 29-03-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 THSYN_RS07890 870aab670aa4b369b31eab420d4e5479 503 SUPERFAMILY SSF51182 206 498 7.91E-79 T 29-03-2018 IPR011051 RmlC-like cupin domain THSYN_RS07890 870aab670aa4b369b31eab420d4e5479 503 SUPERFAMILY SSF53448 2 311 2.6E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS07890 870aab670aa4b369b31eab420d4e5479 503 Gene3D G3DSA:2.60.120.10 367 476 4.4E-30 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS22150 0f6c7df7c362ed78a008b28c15bfb15e 428 Pfam PF01743 Poly A polymerase head domain 18 137 1.5E-18 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 THSYN_RS22150 0f6c7df7c362ed78a008b28c15bfb15e 428 SUPERFAMILY SSF81301 13 134 6.21E-31 T 29-03-2018 THSYN_RS22150 0f6c7df7c362ed78a008b28c15bfb15e 428 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 164 226 6.4E-13 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 THSYN_RS22150 0f6c7df7c362ed78a008b28c15bfb15e 428 Gene3D G3DSA:1.10.3090.10 134 418 6.5E-55 T 29-03-2018 THSYN_RS22150 0f6c7df7c362ed78a008b28c15bfb15e 428 PIRSF PIRSF000813 16 422 7.7E-187 T 29-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 THSYN_RS22150 0f6c7df7c362ed78a008b28c15bfb15e 428 Hamap MF_01261 Multifunctional CCA protein [cca]. 16 422 50.957 T 29-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 THSYN_RS22150 0f6c7df7c362ed78a008b28c15bfb15e 428 SMART SM00471 239 353 0.0097 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS22150 0f6c7df7c362ed78a008b28c15bfb15e 428 SUPERFAMILY SSF81891 135 374 2.09E-53 T 29-03-2018 THSYN_RS22150 0f6c7df7c362ed78a008b28c15bfb15e 428 Hamap MF_01262 CCA-adding enzyme [cca]. 16 416 40.184 T 29-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 THSYN_RS22150 0f6c7df7c362ed78a008b28c15bfb15e 428 Gene3D G3DSA:3.30.460.10 11 133 2.7E-29 T 29-03-2018 THSYN_RS22150 0f6c7df7c362ed78a008b28c15bfb15e 428 Pfam PF01966 HD domain 246 324 8.9E-9 T 29-03-2018 IPR006674 HD domain THSYN_RS22685 efd7f83c0ed3b059c9c47a739cc526e8 136 Pfam PF02635 DsrE/DsrF-like family 6 136 2.3E-23 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein THSYN_RS22685 efd7f83c0ed3b059c9c47a739cc526e8 136 SUPERFAMILY SSF75169 5 136 1.15E-37 T 29-03-2018 IPR027396 DsrEFH-like THSYN_RS22685 efd7f83c0ed3b059c9c47a739cc526e8 136 Gene3D G3DSA:3.40.1260.10 5 136 1.8E-22 T 29-03-2018 THSYN_RS22685 efd7f83c0ed3b059c9c47a739cc526e8 136 TIGRFAM TIGR03010 sulf_tusC_dsrF: sulfur relay protein TusC/DsrF 7 100 9.6E-31 T 29-03-2018 IPR017462 Sulphur relay, TusC/DsrF THSYN_RS10550 b32287fc6f5a3aee34d4caed7d7da7ca 60 Pfam PF12833 Helix-turn-helix domain 1 56 2.1E-10 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THSYN_RS10550 b32287fc6f5a3aee34d4caed7d7da7ca 60 SUPERFAMILY SSF46689 11 56 3.05E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS10550 b32287fc6f5a3aee34d4caed7d7da7ca 60 Gene3D G3DSA:1.10.10.60 5 58 4.3E-11 T 29-03-2018 THSYN_RS10895 9746e29b8d42c96d29295afd1dd2e168 371 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 369 33.241 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 THSYN_RS10895 9746e29b8d42c96d29295afd1dd2e168 371 SUPERFAMILY SSF55347 135 356 4.91E-73 T 29-03-2018 THSYN_RS10895 9746e29b8d42c96d29295afd1dd2e168 371 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 122 6.1E-21 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THSYN_RS10895 9746e29b8d42c96d29295afd1dd2e168 371 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 3 369 2.1E-178 T 29-03-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 THSYN_RS10895 9746e29b8d42c96d29295afd1dd2e168 371 PIRSF PIRSF000148 1 371 5.1E-62 T 29-03-2018 THSYN_RS10895 9746e29b8d42c96d29295afd1dd2e168 371 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 263 277 - T 29-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 THSYN_RS10895 9746e29b8d42c96d29295afd1dd2e168 371 Gene3D G3DSA:3.30.360.10 146 352 7.6E-56 T 29-03-2018 THSYN_RS10895 9746e29b8d42c96d29295afd1dd2e168 371 SMART SM00859 3 123 9.1E-27 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THSYN_RS10895 9746e29b8d42c96d29295afd1dd2e168 371 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 146 355 1.1E-51 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THSYN_RS10895 9746e29b8d42c96d29295afd1dd2e168 371 SUPERFAMILY SSF51735 1 148 1.66E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS10895 9746e29b8d42c96d29295afd1dd2e168 371 Gene3D G3DSA:3.40.50.720 2 145 9.0E-17 T 29-03-2018 THSYN_RS18755 32ce25d4ce319b2609fb077d2d3c09ce 136 SMART SM00749 71 134 6.8E-5 T 29-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria THSYN_RS18755 32ce25d4ce319b2609fb077d2d3c09ce 136 Pfam PF04972 BON domain 66 133 5.9E-18 T 29-03-2018 IPR007055 BON domain THSYN_RS18755 32ce25d4ce319b2609fb077d2d3c09ce 136 Gene3D G3DSA:1.10.8.10 30 76 8.6E-4 T 29-03-2018 THSYN_RS08640 a728a5ae7fed084d45dcc3ea22f873c4 376 Pfam PF03054 tRNA methyl transferase 17 370 9.4E-127 T 29-03-2018 THSYN_RS08640 a728a5ae7fed084d45dcc3ea22f873c4 376 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 17 369 4.8E-124 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 THSYN_RS08640 a728a5ae7fed084d45dcc3ea22f873c4 376 SUPERFAMILY SSF52402 15 253 5.07E-56 T 29-03-2018 THSYN_RS08640 a728a5ae7fed084d45dcc3ea22f873c4 376 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 16 371 36.95 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 THSYN_RS08640 a728a5ae7fed084d45dcc3ea22f873c4 376 Gene3D G3DSA:2.40.30.10 291 376 7.2E-26 T 29-03-2018 THSYN_RS08640 a728a5ae7fed084d45dcc3ea22f873c4 376 Gene3D G3DSA:3.40.50.620 7 221 2.8E-61 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS08640 a728a5ae7fed084d45dcc3ea22f873c4 376 Gene3D G3DSA:2.30.30.280 222 289 1.1E-23 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 THSYN_RS15325 70dc1b74fc48f9862a640a9a1006cbf5 350 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 218 341 1.1E-12 T 29-03-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal THSYN_RS22085 71c72de5e939d3d76bf6d96b8e381c63 440 Gene3D G3DSA:1.25.40.10 59 210 1.2E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22085 71c72de5e939d3d76bf6d96b8e381c63 440 SUPERFAMILY SSF48452 78 252 8.34E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22085 71c72de5e939d3d76bf6d96b8e381c63 440 Gene3D G3DSA:1.25.40.10 211 321 8.5E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22085 71c72de5e939d3d76bf6d96b8e381c63 440 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 44 427 35.054 T 29-03-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 THSYN_RS31540 0ba74ab2e1708ef83cc3ee331c57860e 242 SMART SM00382 35 234 2.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS31540 0ba74ab2e1708ef83cc3ee331c57860e 242 SUPERFAMILY SSF52540 30 218 2.48E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31540 0ba74ab2e1708ef83cc3ee331c57860e 242 Gene3D G3DSA:3.40.50.300 10 233 3.4E-40 T 29-03-2018 THSYN_RS31540 0ba74ab2e1708ef83cc3ee331c57860e 242 Pfam PF00005 ABC transporter 30 182 1.8E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS31540 0ba74ab2e1708ef83cc3ee331c57860e 242 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS25080 3962cf105336afe9f3e89f05fb6050b1 345 Pfam PF13524 Glycosyl transferases group 1 243 341 5.7E-20 T 29-03-2018 THSYN_RS25080 3962cf105336afe9f3e89f05fb6050b1 345 Gene3D G3DSA:3.40.50.2000 70 331 2.3E-9 T 29-03-2018 THSYN_RS23675 d25b32cf87d992d0b638c60a98513a61 487 SUPERFAMILY SSF143968 323 486 2.22E-68 T 29-03-2018 THSYN_RS23675 d25b32cf87d992d0b638c60a98513a61 487 Gene3D G3DSA:1.20.5.570 460 487 1.8E-17 T 29-03-2018 THSYN_RS23675 d25b32cf87d992d0b638c60a98513a61 487 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 431 2.2E-170 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 THSYN_RS23675 d25b32cf87d992d0b638c60a98513a61 487 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 455 9.3E-169 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 THSYN_RS23675 d25b32cf87d992d0b638c60a98513a61 487 SUPERFAMILY SSF50475 3 322 2.43E-122 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 THSYN_RS23675 d25b32cf87d992d0b638c60a98513a61 487 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 487 70.972 T 29-03-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 THSYN_RS23675 d25b32cf87d992d0b638c60a98513a61 487 Gene3D G3DSA:3.40.1670.10 323 459 3.5E-52 T 29-03-2018 THSYN_RS12865 c3334adcde64f6b95e40e5181b7f3b87 356 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 349 51.315 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THSYN_RS12865 c3334adcde64f6b95e40e5181b7f3b87 356 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 142 158 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THSYN_RS12865 c3334adcde64f6b95e40e5181b7f3b87 356 SUPERFAMILY SSF51726 3 352 1.19E-124 T 29-03-2018 THSYN_RS12865 c3334adcde64f6b95e40e5181b7f3b87 356 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 5 347 5.3E-144 T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THSYN_RS12865 c3334adcde64f6b95e40e5181b7f3b87 356 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 9 347 9.2E-137 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THSYN_RS12865 c3334adcde64f6b95e40e5181b7f3b87 356 Gene3D G3DSA:3.20.20.210 1 355 2.4E-114 T 29-03-2018 THSYN_RS12865 c3334adcde64f6b95e40e5181b7f3b87 356 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THSYN_RS21380 e9345aef609ba1c6d9d4e29a5b810437 297 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 3 264 4.8E-107 T 29-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 THSYN_RS21380 e9345aef609ba1c6d9d4e29a5b810437 297 Gene3D G3DSA:3.40.50.620 1 118 1.9E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS21380 e9345aef609ba1c6d9d4e29a5b810437 297 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 235 1.0E-39 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 THSYN_RS21380 e9345aef609ba1c6d9d4e29a5b810437 297 Gene3D G3DSA:3.40.50.620 119 226 3.4E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS21380 e9345aef609ba1c6d9d4e29a5b810437 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 7.8E-12 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 THSYN_RS21380 e9345aef609ba1c6d9d4e29a5b810437 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 174 184 7.8E-12 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 THSYN_RS21380 e9345aef609ba1c6d9d4e29a5b810437 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 190 198 7.8E-12 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 THSYN_RS21380 e9345aef609ba1c6d9d4e29a5b810437 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 7.8E-12 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 THSYN_RS21380 e9345aef609ba1c6d9d4e29a5b810437 297 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 3 292 42.19 T 29-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 THSYN_RS21380 e9345aef609ba1c6d9d4e29a5b810437 297 SUPERFAMILY SSF52374 3 281 1.31E-79 T 29-03-2018 THSYN_RS09090 eaef56422f6a20f7d91fa88efbb28ccf 103 Gene3D G3DSA:2.60.40.10 2 102 5.3E-34 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS09090 eaef56422f6a20f7d91fa88efbb28ccf 103 Pfam PF08770 Sulphur oxidation protein SoxZ 6 100 5.3E-35 T 29-03-2018 IPR014880 Sulphur oxidation protein SoxZ THSYN_RS09090 eaef56422f6a20f7d91fa88efbb28ccf 103 TIGRFAM TIGR04490 SoxZ_true: thiosulfate oxidation carrier complex protein SoxZ 5 102 3.8E-38 T 29-03-2018 IPR030995 Thiosulfate oxidation carrier complex protein SoxZ THSYN_RS09090 eaef56422f6a20f7d91fa88efbb28ccf 103 SUPERFAMILY SSF81296 1 102 1.54E-28 T 29-03-2018 IPR014756 Immunoglobulin E-set THSYN_RS20540 23a45f6deb67d17034e157fbecb0d3b1 177 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 18 170 2.3E-65 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 THSYN_RS20540 23a45f6deb67d17034e157fbecb0d3b1 177 Pfam PF00731 AIR carboxylase 18 161 2.2E-66 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 THSYN_RS20540 23a45f6deb67d17034e157fbecb0d3b1 177 PIRSF PIRSF001338 13 176 9.7E-70 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 THSYN_RS20540 23a45f6deb67d17034e157fbecb0d3b1 177 SUPERFAMILY SSF52255 16 172 1.06E-65 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 THSYN_RS20540 23a45f6deb67d17034e157fbecb0d3b1 177 Gene3D G3DSA:3.40.50.7700 10 174 7.0E-71 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 THSYN_RS20540 23a45f6deb67d17034e157fbecb0d3b1 177 SMART SM01001 16 165 1.1E-99 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 THSYN_RS20540 23a45f6deb67d17034e157fbecb0d3b1 177 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 18 169 33.544 T 29-03-2018 IPR033747 Class I PurE THSYN_RS29300 17a3bb6966edb12db05040aae40e64ab 301 Pfam PF07042 TrfA protein 48 286 1.0E-38 T 29-03-2018 IPR010751 Plasmid replication initiator protein TrfA THSYN_RS06310 ff6ab8c2e5b91f9ad0627b458ac9f566 544 ProSitePatterns PS00455 Putative AMP-binding domain signature. 190 201 - T 29-03-2018 IPR020845 AMP-binding, conserved site THSYN_RS06310 ff6ab8c2e5b91f9ad0627b458ac9f566 544 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 530 4.7E-19 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain THSYN_RS06310 ff6ab8c2e5b91f9ad0627b458ac9f566 544 Gene3D G3DSA:3.30.300.30 442 544 4.5E-26 T 29-03-2018 THSYN_RS06310 ff6ab8c2e5b91f9ad0627b458ac9f566 544 Gene3D G3DSA:3.40.50.980 192 345 8.1E-33 T 29-03-2018 THSYN_RS06310 ff6ab8c2e5b91f9ad0627b458ac9f566 544 Pfam PF00501 AMP-binding enzyme 29 447 1.5E-93 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THSYN_RS06310 ff6ab8c2e5b91f9ad0627b458ac9f566 544 SUPERFAMILY SSF56801 11 542 5.76E-137 T 29-03-2018 THSYN_RS06310 ff6ab8c2e5b91f9ad0627b458ac9f566 544 Gene3D G3DSA:3.40.50.980 23 191 5.4E-36 T 29-03-2018 THSYN_RS06310 ff6ab8c2e5b91f9ad0627b458ac9f566 544 Gene3D G3DSA:2.30.38.10 365 441 6.8E-18 T 29-03-2018 THSYN_RS05365 9850071365446cc738eb7eac5ddb36a1 111 Pfam PF09723 Zinc ribbon domain 1 41 2.0E-18 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain THSYN_RS05365 9850071365446cc738eb7eac5ddb36a1 111 SMART SM00834 1 42 4.6E-22 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain THSYN_RS05365 9850071365446cc738eb7eac5ddb36a1 111 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 5.7E-24 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain THSYN_RS03055 d2154368be57cf1f1faae4f4eec48ee5 405 Pfam PF12704 MacB-like periplasmic core domain 17 260 2.5E-12 T 29-03-2018 IPR025857 MacB-like periplasmic core domain THSYN_RS03055 d2154368be57cf1f1faae4f4eec48ee5 405 Pfam PF02687 FtsX-like permease family 316 399 5.2E-6 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 Gene3D G3DSA:3.30.70.100 685 728 0.0011 T 29-03-2018 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 Gene3D G3DSA:3.30.70.100 624 684 1.3E-10 T 29-03-2018 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 Gene3D G3DSA:3.40.50.10140 54 179 1.5E-16 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 SUPERFAMILY SSF48452 633 721 1.01E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 SUPERFAMILY SSF52540 198 417 1.66E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 SUPERFAMILY SSF52200 53 165 4.58E-15 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 Pfam PF00931 NB-ARC domain 227 407 1.5E-6 T 29-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 SMART SM00028 643 676 2.7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 SMART SM00028 683 716 3.3 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 Pfam PF13676 TIR domain 58 154 3.5E-15 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 Pfam PF13176 Tetratricopeptide repeat 646 678 7.0E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 PRINTS PR00364 Disease resistance protein signature 387 401 1.7E-9 T 29-03-2018 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 PRINTS PR00364 Disease resistance protein signature 307 321 1.7E-9 T 29-03-2018 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 PRINTS PR00364 Disease resistance protein signature 231 246 1.7E-9 T 29-03-2018 THSYN_RS27910 8e05d3e642e968982327b841477dcbda 732 Gene3D G3DSA:3.40.50.300 193 349 2.6E-11 T 29-03-2018 THSYN_RS01875 456d1c5a8d09de103d0f69fb5c87e1eb 605 Gene3D G3DSA:3.40.50.980 12 197 1.3E-43 T 29-03-2018 THSYN_RS01875 456d1c5a8d09de103d0f69fb5c87e1eb 605 Gene3D G3DSA:3.30.300.30 468 603 4.0E-13 T 29-03-2018 THSYN_RS01875 456d1c5a8d09de103d0f69fb5c87e1eb 605 SUPERFAMILY SSF56801 13 294 7.72E-122 T 29-03-2018 THSYN_RS01875 456d1c5a8d09de103d0f69fb5c87e1eb 605 SUPERFAMILY SSF56801 344 602 7.72E-122 T 29-03-2018 THSYN_RS01875 456d1c5a8d09de103d0f69fb5c87e1eb 605 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 29-03-2018 IPR020845 AMP-binding, conserved site THSYN_RS01875 456d1c5a8d09de103d0f69fb5c87e1eb 605 Gene3D G3DSA:2.30.38.10 397 466 1.8E-15 T 29-03-2018 THSYN_RS01875 456d1c5a8d09de103d0f69fb5c87e1eb 605 Gene3D G3DSA:3.40.50.980 198 396 2.7E-47 T 29-03-2018 THSYN_RS01875 456d1c5a8d09de103d0f69fb5c87e1eb 605 Pfam PF00501 AMP-binding enzyme 21 473 9.4E-96 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THSYN_RS05660 14aa1b78296e80bf7a3c157ce75621f8 445 Gene3D G3DSA:3.40.50.720 228 436 3.9E-69 T 29-03-2018 THSYN_RS05660 14aa1b78296e80bf7a3c157ce75621f8 445 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 186 1.0E-62 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THSYN_RS05660 14aa1b78296e80bf7a3c157ce75621f8 445 SMART SM00984 320 424 3.2E-50 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THSYN_RS05660 14aa1b78296e80bf7a3c157ce75621f8 445 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 423 1.6E-30 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THSYN_RS05660 14aa1b78296e80bf7a3c157ce75621f8 445 SUPERFAMILY SSF51735 1 195 2.33E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS05660 14aa1b78296e80bf7a3c157ce75621f8 445 Gene3D G3DSA:1.20.5.170 204 227 1.2E-14 T 29-03-2018 THSYN_RS05660 14aa1b78296e80bf7a3c157ce75621f8 445 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 295 1.2E-37 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THSYN_RS05660 14aa1b78296e80bf7a3c157ce75621f8 445 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 420 9.6E-136 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THSYN_RS05660 14aa1b78296e80bf7a3c157ce75621f8 445 SUPERFAMILY SSF48179 203 301 1.04E-32 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THSYN_RS05660 14aa1b78296e80bf7a3c157ce75621f8 445 Gene3D G3DSA:3.40.50.720 1 202 5.7E-60 T 29-03-2018 THSYN_RS05660 14aa1b78296e80bf7a3c157ce75621f8 445 PIRSF PIRSF000124 1 439 3.1E-148 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THSYN_RS05660 14aa1b78296e80bf7a3c157ce75621f8 445 SUPERFAMILY SSF52413 308 434 6.15E-39 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THSYN_RS05660 14aa1b78296e80bf7a3c157ce75621f8 445 PIRSF PIRSF500134 1 442 4.6E-186 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 THSYN_RS01380 be74f9f87cf415609ef1fc6c8b737892 89 SUPERFAMILY SSF47598 6 48 6.56E-9 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS01380 be74f9f87cf415609ef1fc6c8b737892 89 Pfam PF01402 Ribbon-helix-helix protein, copG family 9 46 3.5E-7 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 THSYN_RS01380 be74f9f87cf415609ef1fc6c8b737892 89 Gene3D G3DSA:1.10.1220.10 2 52 2.0E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS18540 06a31077a8ca8dce04481d52f89afb6e 1011 SUPERFAMILY SSF53335 221 344 2.21E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS18540 06a31077a8ca8dce04481d52f89afb6e 1011 SUPERFAMILY SSF53335 432 515 2.21E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS18540 06a31077a8ca8dce04481d52f89afb6e 1011 SUPERFAMILY SSF53335 143 192 2.21E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS18540 06a31077a8ca8dce04481d52f89afb6e 1011 Gene3D G3DSA:3.40.50.150 146 518 2.5E-48 T 29-03-2018 THSYN_RS18540 06a31077a8ca8dce04481d52f89afb6e 1011 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 449 471 2.6E-14 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS18540 06a31077a8ca8dce04481d52f89afb6e 1011 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 472 486 2.6E-14 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS18540 06a31077a8ca8dce04481d52f89afb6e 1011 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 171 183 2.6E-14 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS18540 06a31077a8ca8dce04481d52f89afb6e 1011 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 233 252 2.6E-14 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS18540 06a31077a8ca8dce04481d52f89afb6e 1011 Pfam PF01555 DNA methylase 171 502 3.9E-30 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THSYN_RS03485 5d046333b14432ad9a96dbc99fe38f95 37 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 12 35 4.9E-5 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS15000 f230de53eed1755cabf193d3b051a127 833 SUPERFAMILY SSF53300 42 215 6.35E-7 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS15000 f230de53eed1755cabf193d3b051a127 833 Gene3D G3DSA:3.40.50.410 37 242 1.4E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS15480 54dd553d11c83245e9f0d6a60dda7137 732 Pfam PF04865 Baseplate J-like protein 442 614 7.4E-16 T 29-03-2018 IPR006949 Baseplate protein J-like THSYN_RS15480 54dd553d11c83245e9f0d6a60dda7137 732 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 350 652 3.3E-63 T 29-03-2018 IPR011749 Conserved hypothetical protein CHP02243 THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 SUPERFAMILY SSF57414 65 105 8.24E-6 T 29-03-2018 THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 Gene3D G3DSA:2.60.40.10 645 853 0.024 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 Pfam PF00207 Alpha-2-macroglobulin family 1220 1288 7.9E-5 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 SMART SM01359 1005 1157 1.2E-38 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 SMART SM01360 1219 1315 7.2E-15 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 541 642 5.6E-26 T 29-03-2018 THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 Gene3D G3DSA:1.50.10.20 1430 1691 1.0E-25 T 29-03-2018 THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 Gene3D G3DSA:1.25.40.10 168 415 2.3E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 Gene3D G3DSA:3.50.4.10 48 127 1.7E-12 T 29-03-2018 THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 SUPERFAMILY SSF48239 1432 1677 8.24E-39 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 PIRSF PIRSF038980 67 1889 0.0 T 29-03-2018 IPR026284 Alpha-2-macroglobulin domain protein, bacteria THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 Gene3D G3DSA:2.60.40.10 550 629 0.0023 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 SMART SM00223 57 123 1.3E-4 T 29-03-2018 IPR000177 Apple domain GO:0005515|GO:0005576|GO:0006508 Reactome: R-HSA-140837 THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 Pfam PF01835 MG2 domain 649 743 9.6E-20 T 29-03-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 1005 1156 6.5E-17 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 THSYN_RS12065 40de3178a41883a00db9631fd43ef6e1 1896 Pfam PF00024 PAN domain 59 106 2.9E-6 T 29-03-2018 IPR003609 PAN/Apple domain THSYN_RS21040 409797866627a97b6b3d7d64b4ddac21 197 Hamap MF_01204 Probable malonic semialdehyde reductase RutE [rutE]. 2 197 42.172 T 29-03-2018 IPR023936 NADH dehydrogenase/NAD(P)H nitroreductase, putative, RutE GO:0016491|GO:0055114 THSYN_RS21040 409797866627a97b6b3d7d64b4ddac21 197 Pfam PF00881 Nitroreductase family 18 175 8.1E-14 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 THSYN_RS21040 409797866627a97b6b3d7d64b4ddac21 197 Gene3D G3DSA:3.40.109.10 3 196 3.3E-33 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THSYN_RS21040 409797866627a97b6b3d7d64b4ddac21 197 SUPERFAMILY SSF55469 15 192 2.22E-41 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THSYN_RS11775 8f7ffa225791477badce05ddc60cde1d 417 Pfam PF00033 Cytochrome b/b6/petB 31 216 2.1E-70 T 29-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 THSYN_RS11775 8f7ffa225791477badce05ddc60cde1d 417 Gene3D G3DSA:1.20.810.10 13 413 4.4E-161 T 29-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 THSYN_RS11775 8f7ffa225791477badce05ddc60cde1d 417 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 287 393 3.4E-41 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 THSYN_RS11775 8f7ffa225791477badce05ddc60cde1d 417 SUPERFAMILY SSF81648 290 409 4.8E-31 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 THSYN_RS11775 8f7ffa225791477badce05ddc60cde1d 417 SUPERFAMILY SSF81342 14 289 3.14E-98 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THSYN_RS11775 8f7ffa225791477badce05ddc60cde1d 417 PIRSF PIRSF038885 3 417 3.6E-162 T 29-03-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 THSYN_RS27665 023086f530ea4218184e8ac40f5ed785 343 SUPERFAMILY SSF56300 117 341 8.78E-31 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS27665 023086f530ea4218184e8ac40f5ed785 343 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 123 281 2.0E-10 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 THSYN_RS27665 023086f530ea4218184e8ac40f5ed785 343 Gene3D G3DSA:3.60.21.10 119 328 1.2E-20 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS23555 bbacda116a173043e61ddda45f3bdda8 361 SUPERFAMILY SSF52540 1 146 1.48E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23555 bbacda116a173043e61ddda45f3bdda8 361 SUPERFAMILY SSF52540 233 315 1.48E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23555 bbacda116a173043e61ddda45f3bdda8 361 Gene3D G3DSA:3.40.50.300 1 124 5.5E-9 T 29-03-2018 THSYN_RS23555 bbacda116a173043e61ddda45f3bdda8 361 Gene3D G3DSA:3.40.50.300 185 320 2.4E-10 T 29-03-2018 THSYN_RS23555 bbacda116a173043e61ddda45f3bdda8 361 Pfam PF13476 AAA domain 4 97 8.2E-9 T 29-03-2018 THSYN_RS23555 bbacda116a173043e61ddda45f3bdda8 361 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 229 308 1.1E-15 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 Pfam PF14561 Tetratricopeptide repeat 202 287 2.1E-22 T 29-03-2018 THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 ProSitePatterns PS00194 Thioredoxin family active site. 29 47 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 Gene3D G3DSA:1.25.40.10 117 199 8.5E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 TIGRFAM TIGR01068 thioredoxin: thioredoxin 11 111 5.5E-29 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 Gene3D G3DSA:3.40.30.10 78 116 2.2E-4 T 29-03-2018 THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 Gene3D G3DSA:1.25.40.10 202 287 2.0E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 SUPERFAMILY SSF52833 4 114 1.16E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 Gene3D G3DSA:3.40.30.10 7 77 9.1E-25 T 29-03-2018 THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 Pfam PF00085 Thioredoxin 7 111 4.3E-27 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 SUPERFAMILY SSF48452 116 249 8.54E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 Pfam PF14559 Tetratricopeptide repeat 126 193 1.8E-8 T 29-03-2018 THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 PRINTS PR00421 Thioredoxin family signature 76 87 8.7E-7 T 29-03-2018 THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 PRINTS PR00421 Thioredoxin family signature 36 45 8.7E-7 T 29-03-2018 THSYN_RS08580 d0fa22d150b7029b093a384f109b8bcf 287 PRINTS PR00421 Thioredoxin family signature 28 36 8.7E-7 T 29-03-2018 THSYN_RS29700 d668967f73fc5c6b20efdcca7ec3d1cd 155 Pfam PF02556 Preprotein translocase subunit SecB 34 135 3.8E-8 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS29700 d668967f73fc5c6b20efdcca7ec3d1cd 155 Gene3D G3DSA:3.10.420.10 2 144 1.2E-20 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS29700 d668967f73fc5c6b20efdcca7ec3d1cd 155 SUPERFAMILY SSF54611 10 137 6.32E-15 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS16670 919bb3b0ee7eed21e3d9060ac0074481 87 SUPERFAMILY SSF47598 3 55 1.78E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS16670 919bb3b0ee7eed21e3d9060ac0074481 87 Gene3D G3DSA:1.10.1220.10 1 77 2.1E-9 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS03695 15b6ea0e4a32927c35a41f6f447422e6 380 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 5 21 1.5E-14 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THSYN_RS03695 15b6ea0e4a32927c35a41f6f447422e6 380 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 160 173 1.5E-14 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THSYN_RS03695 15b6ea0e4a32927c35a41f6f447422e6 380 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 114 128 1.5E-14 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THSYN_RS03695 15b6ea0e4a32927c35a41f6f447422e6 380 SUPERFAMILY SSF53335 3 328 3.29E-88 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS03695 15b6ea0e4a32927c35a41f6f447422e6 380 Gene3D G3DSA:3.40.50.150 5 169 9.8E-53 T 29-03-2018 THSYN_RS03695 15b6ea0e4a32927c35a41f6f447422e6 380 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 75 87 - T 29-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 THSYN_RS03695 15b6ea0e4a32927c35a41f6f447422e6 380 Gene3D G3DSA:3.90.120.10 170 317 9.2E-31 T 29-03-2018 THSYN_RS03695 15b6ea0e4a32927c35a41f6f447422e6 380 Pfam PF00145 C-5 cytosine-specific DNA methylase 6 325 1.1E-61 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS03695 15b6ea0e4a32927c35a41f6f447422e6 380 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 310 328 - T 29-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 THSYN_RS03695 15b6ea0e4a32927c35a41f6f447422e6 380 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 7 182 1.2E-45 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 Pfam PF08447 PAS fold 378 460 3.4E-10 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 352 475 1.6E-19 T 29-03-2018 IPR000014 PAS domain THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 Pfam PF00512 His Kinase A (phospho-acceptor) domain 502 566 1.8E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 Gene3D G3DSA:3.30.565.10 568 721 4.8E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 PRINTS PR00344 Bacterial sensor protein C-terminal signature 681 699 1.9E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 PRINTS PR00344 Bacterial sensor protein C-terminal signature 705 718 1.9E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 PRINTS PR00344 Bacterial sensor protein C-terminal signature 648 662 1.9E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 SMART SM00091 354 420 2.0E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 SUPERFAMILY SSF47384 487 565 1.12E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 Gene3D G3DSA:1.10.287.130 505 564 1.5E-12 T 29-03-2018 THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 SMART SM00387 609 721 2.4E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 Gene3D G3DSA:3.30.450.20 351 504 2.5E-25 T 29-03-2018 THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 SUPERFAMILY SSF55874 557 722 4.71E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 SMART SM00388 500 568 1.4E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 SUPERFAMILY SSF55785 343 466 4.89E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 Gene3D G3DSA:3.30.450.20 97 298 1.1E-5 T 29-03-2018 THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 610 719 3.4E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS29455 898d09d383f137c814a13b96be268ee3 729 SMART SM00086 427 469 1.8E-5 T 29-03-2018 IPR001610 PAC motif THSYN_RS16990 4d5bd2919fcdaf919a773a920a4aa362 511 SUPERFAMILY SSF52172 147 269 1.08E-28 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS16990 4d5bd2919fcdaf919a773a920a4aa362 511 SUPERFAMILY SSF81606 307 506 4.84E-11 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS16990 4d5bd2919fcdaf919a773a920a4aa362 511 Gene3D G3DSA:3.60.40.10 293 510 2.4E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS16990 4d5bd2919fcdaf919a773a920a4aa362 511 Gene3D G3DSA:3.40.50.2300 151 292 4.1E-29 T 29-03-2018 THSYN_RS16990 4d5bd2919fcdaf919a773a920a4aa362 511 SUPERFAMILY SSF55874 35 119 5.02E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS16990 4d5bd2919fcdaf919a773a920a4aa362 511 Gene3D G3DSA:3.30.565.10 2 150 1.2E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS16990 4d5bd2919fcdaf919a773a920a4aa362 511 Pfam PF00072 Response regulator receiver domain 147 258 3.4E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS16990 4d5bd2919fcdaf919a773a920a4aa362 511 Pfam PF13581 Histidine kinase-like ATPase domain 12 127 1.1E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS16990 4d5bd2919fcdaf919a773a920a4aa362 511 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 318 507 1.6E-27 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS16990 4d5bd2919fcdaf919a773a920a4aa362 511 SMART SM00331 293 508 1.4E-16 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS16990 4d5bd2919fcdaf919a773a920a4aa362 511 SMART SM00448 145 257 4.7E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 SUPERFAMILY SSF52283 389 468 3.12E-117 T 29-03-2018 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 SUPERFAMILY SSF52283 181 228 3.12E-117 T 29-03-2018 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 SUPERFAMILY SSF52283 4 143 3.12E-117 T 29-03-2018 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 Gene3D G3DSA:3.40.50.1480 247 441 3.1E-81 T 29-03-2018 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 Gene3D G3DSA:3.40.50.1480 1 246 7.0E-97 T 29-03-2018 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 SMART SM00996 6 467 0.0 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 251 267 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 SUPERFAMILY SSF51735 229 388 2.02E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 PIRSF PIRSF001109 1 468 7.8E-193 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 SMART SM00997 229 388 1.3E-115 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 460 49.406 T 29-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 460 2.7E-190 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 229 388 3.0E-82 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THSYN_RS04855 8d00686505c39ba387bfd2a7aadd0ca6 468 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 6 467 6.4E-149 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THSYN_RS28135 3d49b62a924d5ff103451ed27323f94f 290 Pfam PF01478 Type IV leader peptidase family 138 244 8.1E-23 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 THSYN_RS28135 3d49b62a924d5ff103451ed27323f94f 290 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 213 224 2.9E-25 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial THSYN_RS28135 3d49b62a924d5ff103451ed27323f94f 290 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 202 212 2.9E-25 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial THSYN_RS28135 3d49b62a924d5ff103451ed27323f94f 290 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 145 162 2.9E-25 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial THSYN_RS28135 3d49b62a924d5ff103451ed27323f94f 290 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 225 240 2.9E-25 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial THSYN_RS28135 3d49b62a924d5ff103451ed27323f94f 290 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 21 126 2.1E-33 T 29-03-2018 IPR010627 Peptidase A24A, N-terminal THSYN_RS23275 7033dde927da062c8d846bdf7876578e 395 Pfam PF00465 Iron-containing alcohol dehydrogenase 12 384 3.6E-93 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 THSYN_RS23275 7033dde927da062c8d846bdf7876578e 395 SUPERFAMILY SSF56796 5 392 3.79E-87 T 29-03-2018 THSYN_RS23275 7033dde927da062c8d846bdf7876578e 395 Gene3D G3DSA:1.20.1090.10 190 394 5.6E-42 T 29-03-2018 THSYN_RS23275 7033dde927da062c8d846bdf7876578e 395 Gene3D G3DSA:3.40.50.1970 2 189 1.8E-37 T 29-03-2018 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 Pfam PF00575 S1 RNA binding domain 24 83 1.8E-4 T 29-03-2018 IPR003029 S1 domain GO:0003676 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 Pfam PF00575 S1 RNA binding domain 197 260 2.8E-14 T 29-03-2018 IPR003029 S1 domain GO:0003676 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 Pfam PF00575 S1 RNA binding domain 288 358 6.4E-19 T 29-03-2018 IPR003029 S1 domain GO:0003676 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 Pfam PF00575 S1 RNA binding domain 115 171 2.7E-6 T 29-03-2018 IPR003029 S1 domain GO:0003676 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 SUPERFAMILY SSF50249 16 119 5.65E-13 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 PRINTS PR00681 Ribosomal protein S1 signature 28 46 7.6E-47 T 29-03-2018 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 PRINTS PR00681 Ribosomal protein S1 signature 46 60 7.6E-47 T 29-03-2018 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 PRINTS PR00681 Ribosomal protein S1 signature 220 241 7.6E-47 T 29-03-2018 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 PRINTS PR00681 Ribosomal protein S1 signature 303 322 7.6E-47 T 29-03-2018 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 PRINTS PR00681 Ribosomal protein S1 signature 343 361 7.6E-47 T 29-03-2018 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 PRINTS PR00681 Ribosomal protein S1 signature 133 150 7.6E-47 T 29-03-2018 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 PRINTS PR00681 Ribosomal protein S1 signature 115 131 7.6E-47 T 29-03-2018 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 PRINTS PR00681 Ribosomal protein S1 signature 163 183 7.6E-47 T 29-03-2018 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 Gene3D G3DSA:2.40.50.140 6 95 5.7E-9 T 29-03-2018 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 SUPERFAMILY SSF50249 268 371 8.58E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 SMART SM00316 288 360 9.6E-24 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 SMART SM00316 110 179 2.4E-6 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 SMART SM00316 198 273 2.7E-21 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 SMART SM00316 26 94 1.9E-5 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 SUPERFAMILY SSF50249 197 290 8.58E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 Gene3D G3DSA:2.40.50.140 106 190 2.7E-9 T 29-03-2018 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 Gene3D G3DSA:2.40.50.140 191 279 3.8E-21 T 29-03-2018 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 Gene3D G3DSA:2.40.50.140 283 366 9.4E-23 T 29-03-2018 THSYN_RS06895 c551537416d8c358b151c376e278b96c 415 SUPERFAMILY SSF50249 111 192 1.34E-11 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS23120 452aa681fdb4fb619f895b1c455c62cc 357 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 113 190 1.2E-17 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THSYN_RS23120 452aa681fdb4fb619f895b1c455c62cc 357 Gene3D G3DSA:3.40.47.10 2 168 3.5E-22 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS23120 452aa681fdb4fb619f895b1c455c62cc 357 SUPERFAMILY SSF53901 8 340 2.84E-50 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS23120 452aa681fdb4fb619f895b1c455c62cc 357 PIRSF PIRSF000429 41 150 2.3E-4 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 THSYN_RS23120 452aa681fdb4fb619f895b1c455c62cc 357 PIRSF PIRSF000429 233 287 6.3 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 THSYN_RS23120 452aa681fdb4fb619f895b1c455c62cc 357 PIRSF PIRSF000429 305 338 580.0 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 THSYN_RS23120 452aa681fdb4fb619f895b1c455c62cc 357 Gene3D G3DSA:3.40.47.10 169 345 3.8E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS23120 452aa681fdb4fb619f895b1c455c62cc 357 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 251 339 6.7E-25 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THSYN_RS05275 b63afebc5b479bdff0b811702f3ccbe3 151 SUPERFAMILY SSF158682 21 147 8.11E-22 T 29-03-2018 THSYN_RS05275 b63afebc5b479bdff0b811702f3ccbe3 151 Gene3D G3DSA:1.10.3680.10 6 149 1.3E-19 T 29-03-2018 IPR029024 TerB-like THSYN_RS05275 b63afebc5b479bdff0b811702f3ccbe3 151 Pfam PF05099 Tellurite resistance protein TerB 9 147 3.9E-26 T 29-03-2018 IPR007791 Co-chaperone DjlA, N-terminal THSYN_RS12915 370baf0c47439317ea02563096cae6c6 184 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 THSYN_RS12915 370baf0c47439317ea02563096cae6c6 184 SMART SM01266 5 59 1.6E-16 T 29-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 THSYN_RS12915 370baf0c47439317ea02563096cae6c6 184 Gene3D G3DSA:2.160.10.10 2 184 2.4E-51 T 29-03-2018 THSYN_RS12915 370baf0c47439317ea02563096cae6c6 184 Pfam PF12464 Maltose acetyltransferase 7 58 7.7E-14 T 29-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 THSYN_RS12915 370baf0c47439317ea02563096cae6c6 184 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 132 165 4.8E-8 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS12915 370baf0c47439317ea02563096cae6c6 184 SUPERFAMILY SSF51161 1 183 2.63E-50 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS10680 6169553911f36ad0639c39ee4c2d8166 1148 SUPERFAMILY SSF52980 855 1143 6.43E-63 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS10680 6169553911f36ad0639c39ee4c2d8166 1148 SUPERFAMILY SSF52540 62 381 2.71E-92 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10680 6169553911f36ad0639c39ee4c2d8166 1148 SUPERFAMILY SSF52540 392 831 3.58E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10680 6169553911f36ad0639c39ee4c2d8166 1148 PIRSF PIRSF000980 62 1148 0.0 T 29-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 THSYN_RS10680 6169553911f36ad0639c39ee4c2d8166 1148 Gene3D G3DSA:1.10.10.160 146 243 4.9E-25 T 29-03-2018 THSYN_RS10680 6169553911f36ad0639c39ee4c2d8166 1148 Gene3D G3DSA:1.10.486.10 469 676 6.2E-64 T 29-03-2018 THSYN_RS10680 6169553911f36ad0639c39ee4c2d8166 1148 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 62 1146 19.363 T 29-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 THSYN_RS10680 6169553911f36ad0639c39ee4c2d8166 1148 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 62 826 9.3E-261 T 29-03-2018 THSYN_RS10680 6169553911f36ad0639c39ee4c2d8166 1148 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 63 1094 3.6E-296 T 29-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 THSYN_RS27950 46f931b404b7d3e1a1f3e49bc4b30536 64 Pfam PF11839 Alanine-zipper, major outer membrane lipoprotein 28 64 2.4E-6 T 29-03-2018 IPR021793 Major outer membrane lipoprotein Oprl THSYN_RS31385 e4064a871e967268d0fb487702b0261b 324 Gene3D G3DSA:1.20.85.10 3 143 1.4E-66 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31385 e4064a871e967268d0fb487702b0261b 324 ProSitePatterns PS00244 Photosynthetic reaction center proteins signature. 195 221 - T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31385 e4064a871e967268d0fb487702b0261b 324 TIGRFAM TIGR01115 pufM: photosynthetic reaction center M subunit 1 304 9.5E-166 T 29-03-2018 IPR005781 Photosynthetic reaction centre, M subunit GO:0019684|GO:0030077|GO:0045156 THSYN_RS31385 e4064a871e967268d0fb487702b0261b 324 PRINTS PR00256 Bacterial photosynthetic reaction centre signature 145 167 1.8E-51 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31385 e4064a871e967268d0fb487702b0261b 324 PRINTS PR00256 Bacterial photosynthetic reaction centre signature 55 76 1.8E-51 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31385 e4064a871e967268d0fb487702b0261b 324 PRINTS PR00256 Bacterial photosynthetic reaction centre signature 261 286 1.8E-51 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31385 e4064a871e967268d0fb487702b0261b 324 PRINTS PR00256 Bacterial photosynthetic reaction centre signature 112 140 1.8E-51 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31385 e4064a871e967268d0fb487702b0261b 324 PRINTS PR00256 Bacterial photosynthetic reaction centre signature 201 227 1.8E-51 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31385 e4064a871e967268d0fb487702b0261b 324 SUPERFAMILY SSF81483 2 317 2.49E-132 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31385 e4064a871e967268d0fb487702b0261b 324 Gene3D G3DSA:1.20.85.10 146 294 4.6E-60 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31385 e4064a871e967268d0fb487702b0261b 324 Pfam PF00124 Photosynthetic reaction centre protein 51 303 1.1E-102 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS11930 87ecec50bb882729c6b4f3aca85d6226 143 Gene3D G3DSA:3.40.50.2300 18 142 2.8E-21 T 29-03-2018 THSYN_RS11930 87ecec50bb882729c6b4f3aca85d6226 143 SUPERFAMILY SSF52172 23 138 1.04E-21 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS11930 87ecec50bb882729c6b4f3aca85d6226 143 SMART SM00448 20 134 7.5E-9 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS11930 87ecec50bb882729c6b4f3aca85d6226 143 Pfam PF00072 Response regulator receiver domain 23 134 7.0E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS32055 b7114739f865d123aa8d1b20193e68e9 339 SUPERFAMILY SSF54211 9 159 2.28E-17 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS32055 b7114739f865d123aa8d1b20193e68e9 339 Pfam PF00288 GHMP kinases N terminal domain 82 124 6.4E-6 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 THSYN_RS32055 b7114739f865d123aa8d1b20193e68e9 339 Gene3D G3DSA:3.30.70.890 172 330 1.4E-9 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain THSYN_RS32055 b7114739f865d123aa8d1b20193e68e9 339 PIRSF PIRSF004884 7 326 1.0E-79 T 29-03-2018 IPR004422 GHMP kinase group 1 MetaCyc: PWY-6148 THSYN_RS32055 b7114739f865d123aa8d1b20193e68e9 339 Gene3D G3DSA:3.30.230.10 8 161 6.8E-13 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS32055 b7114739f865d123aa8d1b20193e68e9 339 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 10 323 3.2E-39 T 29-03-2018 IPR004422 GHMP kinase group 1 MetaCyc: PWY-6148 THSYN_RS30965 7460a88bf53374955b3225f5041a1b9a 323 SUPERFAMILY SSF144083 258 320 4.05E-16 T 29-03-2018 THSYN_RS30965 7460a88bf53374955b3225f5041a1b9a 323 SUPERFAMILY SSF143865 10 249 3.79E-25 T 29-03-2018 THSYN_RS30965 7460a88bf53374955b3225f5041a1b9a 323 Gene3D G3DSA:1.20.58.340 138 256 3.5E-6 T 29-03-2018 THSYN_RS30965 7460a88bf53374955b3225f5041a1b9a 323 Gene3D G3DSA:1.20.58.340 257 323 6.9E-16 T 29-03-2018 THSYN_RS30965 7460a88bf53374955b3225f5041a1b9a 323 Gene3D G3DSA:3.30.460.20 4 135 1.8E-9 T 29-03-2018 THSYN_RS30965 7460a88bf53374955b3225f5041a1b9a 323 Pfam PF01544 CorA-like Mg2+ transporter protein 39 320 1.9E-42 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 THSYN_RS16010 d8ed1b9cedc2fae596ec61389aef29f8 132 TIGRFAM TIGR02293 TAS_TIGR02293: putative toxin-antitoxin system antitoxin component, TIGR02293 family 9 132 3.0E-34 T 29-03-2018 IPR011979 Conserved hypothetical protein CHP02293 THSYN_RS16010 d8ed1b9cedc2fae596ec61389aef29f8 132 Pfam PF09722 Protein of unknown function (DUF2384) 79 129 2.7E-14 T 29-03-2018 IPR024467 Domain of unknown function DUF2384 THSYN_RS23350 da40d942c581c134155a2e7320fc7593 606 Gene3D G3DSA:3.30.70.270 190 386 2.0E-18 T 29-03-2018 THSYN_RS23350 da40d942c581c134155a2e7320fc7593 606 SUPERFAMILY SSF55271 483 570 1.44E-11 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 THSYN_RS23350 da40d942c581c134155a2e7320fc7593 606 SUPERFAMILY SSF56672 127 441 2.41E-26 T 29-03-2018 THSYN_RS23350 da40d942c581c134155a2e7320fc7593 606 Pfam PF01624 MutS domain I 488 585 9.9E-7 T 29-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 THSYN_RS23350 da40d942c581c134155a2e7320fc7593 606 Gene3D G3DSA:3.40.1170.10 481 584 2.7E-9 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 THSYN_RS23350 da40d942c581c134155a2e7320fc7593 606 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 159 263 8.3E-7 T 29-03-2018 IPR000477 Reverse transcriptase domain THSYN_RS03960 24631eef389ffc8d48048ed73f3342f3 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.5E-29 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THSYN_RS03960 24631eef389ffc8d48048ed73f3342f3 68 Gene3D G3DSA:2.40.50.140 1 67 2.4E-28 T 29-03-2018 THSYN_RS03960 24631eef389ffc8d48048ed73f3342f3 68 SMART SM00357 3 67 2.3E-28 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 THSYN_RS03960 24631eef389ffc8d48048ed73f3342f3 68 PRINTS PR00050 Cold shock protein signature 25 34 4.5E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THSYN_RS03960 24631eef389ffc8d48048ed73f3342f3 68 PRINTS PR00050 Cold shock protein signature 40 58 4.5E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THSYN_RS03960 24631eef389ffc8d48048ed73f3342f3 68 PRINTS PR00050 Cold shock protein signature 4 19 4.5E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THSYN_RS03960 24631eef389ffc8d48048ed73f3342f3 68 PIRSF PIRSF002599 1 68 1.8E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 THSYN_RS03960 24631eef389ffc8d48048ed73f3342f3 68 TIGRFAM TIGR02381 cspD: cold shock domain protein CspD 1 67 5.8E-35 T 29-03-2018 IPR012751 CspD, cold shock GO:0003676|GO:0005737|GO:0006355|GO:0006950 THSYN_RS03960 24631eef389ffc8d48048ed73f3342f3 68 SUPERFAMILY SSF50249 1 67 2.49E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS33225 94287e1aebd154547ad532e5ecf6b96b 1150 SMART SM00490 849 953 0.008 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS33225 94287e1aebd154547ad532e5ecf6b96b 1150 SUPERFAMILY SSF52540 874 989 2.85E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS33225 94287e1aebd154547ad532e5ecf6b96b 1150 SUPERFAMILY SSF52540 451 511 2.85E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS33225 94287e1aebd154547ad532e5ecf6b96b 1150 SUPERFAMILY SSF52540 636 648 4.03E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS33225 94287e1aebd154547ad532e5ecf6b96b 1150 SUPERFAMILY SSF52540 678 758 4.03E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS33225 94287e1aebd154547ad532e5ecf6b96b 1150 SUPERFAMILY SSF52540 418 548 4.03E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS33225 94287e1aebd154547ad532e5ecf6b96b 1150 Gene3D G3DSA:3.40.50.300 400 742 1.2E-8 T 29-03-2018 THSYN_RS33225 94287e1aebd154547ad532e5ecf6b96b 1150 Gene3D G3DSA:3.40.50.300 743 993 4.4E-13 T 29-03-2018 THSYN_RS33225 94287e1aebd154547ad532e5ecf6b96b 1150 Pfam PF00271 Helicase conserved C-terminal domain 885 951 3.8E-6 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS22155 07ff0f1b0b6e8d749fb9800ece3ec9c3 266 Gene3D G3DSA:3.40.710.10 20 252 1.1E-28 T 29-03-2018 THSYN_RS22155 07ff0f1b0b6e8d749fb9800ece3ec9c3 266 Pfam PF00905 Penicillin binding protein transpeptidase domain 57 251 6.4E-32 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THSYN_RS22155 07ff0f1b0b6e8d749fb9800ece3ec9c3 266 ProSitePatterns PS00337 Beta-lactamase class-D active site. 64 74 - T 29-03-2018 IPR002137 Beta-lactamase, class-D active site GO:0008800|GO:0017001 KEGG: 00311+3.5.2.6 THSYN_RS22155 07ff0f1b0b6e8d749fb9800ece3ec9c3 266 SUPERFAMILY SSF56601 29 255 1.49E-38 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS27185 3bdb83e07c0e4043dae3afb639bba085 754 SUPERFAMILY SSF53244 586 713 1.15E-28 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THSYN_RS27185 3bdb83e07c0e4043dae3afb639bba085 754 Gene3D G3DSA:3.90.190.20 587 727 9.6E-25 T 29-03-2018 THSYN_RS27185 3bdb83e07c0e4043dae3afb639bba085 754 Pfam PF02875 Mur ligase family, glutamate ligase domain 586 662 8.1E-12 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THSYN_RS27185 3bdb83e07c0e4043dae3afb639bba085 754 SUPERFAMILY SSF53623 329 599 9.62E-38 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS27185 3bdb83e07c0e4043dae3afb639bba085 754 Pfam PF08245 Mur ligase middle domain 349 560 1.3E-18 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS27185 3bdb83e07c0e4043dae3afb639bba085 754 Gene3D G3DSA:3.40.1190.10 326 579 2.1E-42 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS18545 8e0aa1866183082dc84ff3a10eac4925 133 SUPERFAMILY SSF88723 1 126 1.15E-23 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS18545 8e0aa1866183082dc84ff3a10eac4925 133 Gene3D G3DSA:3.40.50.1010 1 133 8.8E-20 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS18545 8e0aa1866183082dc84ff3a10eac4925 133 Pfam PF01850 PIN domain 5 122 2.1E-12 T 29-03-2018 IPR002716 PIN domain THSYN_RS14840 760773437509c29e1ff217d0bd236eea 992 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 708 977 1.3E-56 T 29-03-2018 IPR022625 Type-1 restriction enzyme R protein, C-terminal THSYN_RS14840 760773437509c29e1ff217d0bd236eea 992 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 2 186 4.5E-31 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THSYN_RS14840 760773437509c29e1ff217d0bd236eea 992 SUPERFAMILY SSF52540 245 415 9.49E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14840 760773437509c29e1ff217d0bd236eea 992 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 3 700 2.7E-115 T 29-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 THSYN_RS14840 760773437509c29e1ff217d0bd236eea 992 SMART SM00487 242 447 1.8E-14 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS14840 760773437509c29e1ff217d0bd236eea 992 Pfam PF04851 Type III restriction enzyme, res subunit 245 413 1.0E-35 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS14840 760773437509c29e1ff217d0bd236eea 992 Gene3D G3DSA:3.40.50.300 241 427 4.2E-25 T 29-03-2018 THSYN_RS21910 54b244a2c9be93267af059ceffc206d6 610 SUPERFAMILY SSF56801 18 292 5.1E-119 T 29-03-2018 THSYN_RS21910 54b244a2c9be93267af059ceffc206d6 610 SUPERFAMILY SSF56801 343 600 5.1E-119 T 29-03-2018 THSYN_RS21910 54b244a2c9be93267af059ceffc206d6 610 Pfam PF00501 AMP-binding enzyme 25 472 8.3E-89 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THSYN_RS21910 54b244a2c9be93267af059ceffc206d6 610 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 29-03-2018 IPR020845 AMP-binding, conserved site THSYN_RS21910 54b244a2c9be93267af059ceffc206d6 610 Gene3D G3DSA:2.30.38.10 393 465 8.0E-19 T 29-03-2018 THSYN_RS21910 54b244a2c9be93267af059ceffc206d6 610 Gene3D G3DSA:3.30.300.30 467 602 8.3E-15 T 29-03-2018 THSYN_RS21910 54b244a2c9be93267af059ceffc206d6 610 Gene3D G3DSA:3.40.50.980 18 193 1.1E-38 T 29-03-2018 THSYN_RS21910 54b244a2c9be93267af059ceffc206d6 610 Gene3D G3DSA:3.40.50.980 194 392 1.4E-42 T 29-03-2018 THSYN_RS07915 1d4f32b97cad0ec176928ef624a391ab 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 301 4.4E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS07915 1d4f32b97cad0ec176928ef624a391ab 306 SUPERFAMILY SSF161098 18 297 4.97E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS07915 1d4f32b97cad0ec176928ef624a391ab 306 Gene3D G3DSA:1.10.3720.10 18 305 4.8E-45 T 29-03-2018 THSYN_RS26040 282e3af2ffe05b838206858cc010558d 397 Gene3D G3DSA:3.40.50.300 3 143 6.2E-12 T 29-03-2018 THSYN_RS26040 282e3af2ffe05b838206858cc010558d 397 Pfam PF13635 Domain of unknown function (DUF4143) 180 337 8.1E-22 T 29-03-2018 IPR025420 Domain of unknown function DUF4143 THSYN_RS26040 282e3af2ffe05b838206858cc010558d 397 Gene3D G3DSA:1.10.10.10 144 258 7.2E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26040 282e3af2ffe05b838206858cc010558d 397 SUPERFAMILY SSF52540 5 183 1.35E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26040 282e3af2ffe05b838206858cc010558d 397 Pfam PF13173 AAA domain 18 138 4.5E-23 T 29-03-2018 THSYN_RS26040 282e3af2ffe05b838206858cc010558d 397 SMART SM00382 16 137 1.5E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS00835 88df87403f28c30fd695e3dc7a81efb2 77 SUPERFAMILY SSF47598 3 67 5.11E-13 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS00835 88df87403f28c30fd695e3dc7a81efb2 77 Gene3D G3DSA:1.10.1220.10 1 55 4.5E-11 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 SUPERFAMILY SSF49299 537 617 2.49E-10 T 29-03-2018 IPR000601 PKD domain THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 Pfam PF00801 PKD domain 629 696 1.7E-6 T 29-03-2018 IPR000601 PKD domain THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 Gene3D G3DSA:2.60.40.10 442 529 5.7E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 Gene3D G3DSA:2.60.40.10 712 805 1.1E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 Gene3D G3DSA:2.60.40.10 531 618 1.2E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 Gene3D G3DSA:2.60.40.10 619 711 4.7E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 SMART SM00089 532 619 3.5E-4 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 SMART SM00089 149 238 0.55 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 SMART SM00089 244 336 11.0 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 SMART SM00089 622 710 4.2E-7 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 SMART SM00089 716 802 3.1E-6 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 SUPERFAMILY SSF49299 613 700 8.11E-15 T 29-03-2018 IPR000601 PKD domain THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 SUPERFAMILY SSF49299 715 799 3.92E-12 T 29-03-2018 IPR000601 PKD domain THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 SUPERFAMILY SSF49299 145 228 6.54E-7 T 29-03-2018 IPR000601 PKD domain THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 Gene3D G3DSA:3.40.1850.10 252 349 2.4E-14 T 29-03-2018 THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 Gene3D G3DSA:3.40.1850.10 350 441 1.6E-13 T 29-03-2018 THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 Gene3D G3DSA:3.40.1850.10 153 251 1.1E-23 T 29-03-2018 THSYN_RS32215 f42c5eb713b56214d7384548a2449058 1110 Pfam PF13860 FlgD Ig-like domain 816 882 2.0E-10 T 29-03-2018 IPR025965 FlgD Ig-like domain THSYN_RS09655 af53d928fd1e86cc27acddb0c91a1e98 398 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 172 354 2.6E-15 T 29-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 THSYN_RS09655 af53d928fd1e86cc27acddb0c91a1e98 398 Gene3D G3DSA:2.30.130.10 4 74 5.7E-22 T 29-03-2018 IPR002478 PUA domain GO:0003723 THSYN_RS09655 af53d928fd1e86cc27acddb0c91a1e98 398 SUPERFAMILY SSF88697 6 75 6.96E-11 T 29-03-2018 IPR015947 PUA-like domain THSYN_RS09655 af53d928fd1e86cc27acddb0c91a1e98 398 Gene3D G3DSA:3.40.50.150 183 396 1.0E-40 T 29-03-2018 THSYN_RS09655 af53d928fd1e86cc27acddb0c91a1e98 398 SUPERFAMILY SSF53335 86 392 9.28E-72 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS09655 af53d928fd1e86cc27acddb0c91a1e98 398 Gene3D G3DSA:3.30.750.80 78 181 3.2E-31 T 29-03-2018 THSYN_RS19245 da01eec816368ec8274c9e39c8dc3f9b 223 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 1 209 4.5E-88 T 29-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 THSYN_RS19245 da01eec816368ec8274c9e39c8dc3f9b 223 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 208 1.7E-50 T 29-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 THSYN_RS19245 da01eec816368ec8274c9e39c8dc3f9b 223 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 1 216 29.061 T 29-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 Gene3D G3DSA:1.10.10.10 334 397 5.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 Gene3D G3DSA:1.10.10.10 504 558 2.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 Gene3D G3DSA:1.10.10.10 420 481 1.7E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 Gene3D G3DSA:1.10.10.10 53 312 5.9E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 PRINTS PR00381 Kinesin light chain signature 432 449 1.0E-10 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 PRINTS PR00381 Kinesin light chain signature 511 532 1.0E-10 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 PRINTS PR00381 Kinesin light chain signature 367 385 1.0E-10 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 PRINTS PR00381 Kinesin light chain signature 476 496 1.0E-10 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 PRINTS PR00381 Kinesin light chain signature 345 364 1.0E-10 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 Gene3D G3DSA:1.20.58.280 482 503 0.11 T 29-03-2018 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 Gene3D G3DSA:1.20.58.280 398 419 0.014 T 29-03-2018 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 SUPERFAMILY SSF48452 270 384 3.8E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 SUPERFAMILY SSF48452 472 621 2.85E-21 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 SMART SM00028 310 343 17.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 SMART SM00028 352 385 15.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 SMART SM00028 478 511 12.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 SMART SM00028 562 595 250.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 SMART SM00028 520 553 13.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 SMART SM00028 436 469 31.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 SMART SM00028 268 301 46.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 SMART SM00028 394 427 17.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 Gene3D G3DSA:1.10.150.200 559 622 0.0019 T 29-03-2018 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 Pfam PF13424 Tetratricopeptide repeat 355 425 1.9E-17 T 29-03-2018 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 Pfam PF13424 Tetratricopeptide repeat 268 341 2.5E-18 T 29-03-2018 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 Pfam PF13424 Tetratricopeptide repeat 531 589 2.2E-12 T 29-03-2018 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 Pfam PF13424 Tetratricopeptide repeat 435 509 2.4E-17 T 29-03-2018 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 SUPERFAMILY SSF48452 388 509 6.5E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS11740 2d015293824456dc71cd37ae3d91ff95 664 Gene3D G3DSA:1.20.58.280 313 333 0.088 T 29-03-2018 THSYN_RS19560 ae8e449b615f77eda17db8c1ed2b59e0 126 Gene3D G3DSA:1.25.10.20 3 122 4.1E-8 T 29-03-2018 THSYN_RS19560 ae8e449b615f77eda17db8c1ed2b59e0 126 Pfam PF13646 HEAT repeats 29 109 1.7E-7 T 29-03-2018 THSYN_RS19560 ae8e449b615f77eda17db8c1ed2b59e0 126 SUPERFAMILY SSF48371 4 109 9.12E-10 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS01230 def7a117f9dc4bc295be1cc574823641 377 Gene3D G3DSA:3.90.1150.10 270 377 3.6E-14 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS01230 def7a117f9dc4bc295be1cc574823641 377 SUPERFAMILY SSF53383 9 372 4.63E-75 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS01230 def7a117f9dc4bc295be1cc574823641 377 Gene3D G3DSA:3.40.640.10 30 269 1.9E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS01230 def7a117f9dc4bc295be1cc574823641 377 PIRSF PIRSF000521 11 119 1.7 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THSYN_RS01230 def7a117f9dc4bc295be1cc574823641 377 PIRSF PIRSF000521 146 375 1.3E-13 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THSYN_RS01230 def7a117f9dc4bc295be1cc574823641 377 Pfam PF00202 Aminotransferase class-III 8 371 6.4E-61 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THSYN_RS01230 def7a117f9dc4bc295be1cc574823641 377 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 202 239 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 Gene3D G3DSA:2.60.34.10 390 531 9.3E-61 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 PRINTS PR00301 70kDa heat shock protein signature 469 485 4.0E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 PRINTS PR00301 70kDa heat shock protein signature 198 208 4.0E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 PRINTS PR00301 70kDa heat shock protein signature 334 350 4.0E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 PRINTS PR00301 70kDa heat shock protein signature 54 62 4.0E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 PRINTS PR00301 70kDa heat shock protein signature 388 407 4.0E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 PRINTS PR00301 70kDa heat shock protein signature 31 43 4.0E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 PRINTS PR00301 70kDa heat shock protein signature 3 16 4.0E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 PRINTS PR00301 70kDa heat shock protein signature 138 158 4.0E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 PRINTS PR00301 70kDa heat shock protein signature 365 385 4.0E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 Pfam PF00012 Hsp70 protein 4 603 1.7E-258 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 SUPERFAMILY SSF53067 4 184 2.88E-67 T 29-03-2018 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 SUPERFAMILY SSF53067 187 382 4.88E-67 T 29-03-2018 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 SUPERFAMILY SSF100934 507 605 1.7E-19 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 603 1.1E-285 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 644 36.358 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 Gene3D G3DSA:1.20.1270.10 532 616 4.4E-19 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 SUPERFAMILY SSF100920 384 540 9.16E-59 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 Gene3D G3DSA:3.30.420.40 197 365 4.0E-46 T 29-03-2018 THSYN_RS26065 5dbe967f258cfde570735d5cdc38b8de 649 Gene3D G3DSA:3.30.420.40 1 196 1.3E-81 T 29-03-2018 THSYN_RS01895 4c0884c30065f23032eca50187d7fe7d 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 29.244 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THSYN_RS01895 4c0884c30065f23032eca50187d7fe7d 90 PIRSF PIRSF029827 1 90 2.3E-41 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THSYN_RS01895 4c0884c30065f23032eca50187d7fe7d 90 Gene3D G3DSA:1.10.3880.10 2 89 1.4E-42 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THSYN_RS01895 4c0884c30065f23032eca50187d7fe7d 90 SUPERFAMILY SSF111148 1 89 1.44E-40 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THSYN_RS01895 4c0884c30065f23032eca50187d7fe7d 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 3.0E-44 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THSYN_RS01895 4c0884c30065f23032eca50187d7fe7d 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 75 3.0E-27 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THSYN_RS11855 b2bfd25250b5402e6791d6d906c955ce 139 Gene3D G3DSA:3.40.50.1010 2 135 4.9E-15 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS11855 b2bfd25250b5402e6791d6d906c955ce 139 Pfam PF01850 PIN domain 4 129 7.0E-6 T 29-03-2018 IPR002716 PIN domain THSYN_RS11855 b2bfd25250b5402e6791d6d906c955ce 139 SUPERFAMILY SSF88723 1 135 9.53E-23 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS29410 89311dd04b42507bed0c600f35fedad0 223 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 60 177 1.9E-33 T 29-03-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated THSYN_RS29410 89311dd04b42507bed0c600f35fedad0 223 SUPERFAMILY SSF53448 24 214 1.82E-39 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS29410 89311dd04b42507bed0c600f35fedad0 223 TIGRFAM TIGR04282 glyco_like_cofC: transferase 1, rSAM/selenodomain-associated 22 210 1.0E-59 T 29-03-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated THSYN_RS29410 89311dd04b42507bed0c600f35fedad0 223 Gene3D G3DSA:3.90.550.10 29 203 7.1E-20 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS10510 0c7c8b2ab1e0d9d400f38eba063393b5 228 Gene3D G3DSA:1.10.10.10 96 169 3.2E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS10510 0c7c8b2ab1e0d9d400f38eba063393b5 228 Pfam PF04337 Protein of unknown function, DUF480 10 156 3.0E-58 T 29-03-2018 IPR007432 Protein of unknown function DUF480 THSYN_RS10510 0c7c8b2ab1e0d9d400f38eba063393b5 228 SUPERFAMILY SSF46785 90 170 3.18E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS10510 0c7c8b2ab1e0d9d400f38eba063393b5 228 SUPERFAMILY SSF46785 8 87 4.13E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS10510 0c7c8b2ab1e0d9d400f38eba063393b5 228 Gene3D G3DSA:1.10.10.10 7 89 7.1E-36 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS10510 0c7c8b2ab1e0d9d400f38eba063393b5 228 Hamap MF_01584 UPF0502 protein YceH [yceH]. 10 219 31.131 T 29-03-2018 IPR007432 Protein of unknown function DUF480 THSYN_RS28245 e73a12faea07888aeba5533e9b4ac31f 343 Gene3D G3DSA:1.10.8.60 142 219 4.5E-16 T 29-03-2018 THSYN_RS28245 e73a12faea07888aeba5533e9b4ac31f 343 Pfam PF06144 DNA polymerase III, delta subunit 20 189 1.4E-20 T 29-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 THSYN_RS28245 e73a12faea07888aeba5533e9b4ac31f 343 SUPERFAMILY SSF52540 1 209 7.12E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS28245 e73a12faea07888aeba5533e9b4ac31f 343 Gene3D G3DSA:1.20.272.10 220 326 5.6E-21 T 29-03-2018 THSYN_RS28245 e73a12faea07888aeba5533e9b4ac31f 343 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 324 3.8E-76 T 29-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 THSYN_RS28245 e73a12faea07888aeba5533e9b4ac31f 343 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 215 314 1.2E-6 T 29-03-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS28245 e73a12faea07888aeba5533e9b4ac31f 343 Gene3D G3DSA:3.40.50.300 1 139 1.5E-16 T 29-03-2018 THSYN_RS28245 e73a12faea07888aeba5533e9b4ac31f 343 SUPERFAMILY SSF48019 211 332 1.33E-22 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 THSYN_RS24530 3829fe95d079eec2d3d7b17464390ac4 246 Gene3D G3DSA:3.40.50.150 7 220 3.2E-17 T 29-03-2018 THSYN_RS24530 3829fe95d079eec2d3d7b17464390ac4 246 Pfam PF13489 Methyltransferase domain 36 211 1.9E-7 T 29-03-2018 THSYN_RS24530 3829fe95d079eec2d3d7b17464390ac4 246 SUPERFAMILY SSF53335 191 218 1.26E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS24530 3829fe95d079eec2d3d7b17464390ac4 246 SUPERFAMILY SSF53335 22 156 1.26E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS27220 1f9f95e6641adf4c182871b428c814dd 759 Gene3D G3DSA:1.20.1560.10 173 498 5.6E-70 T 29-03-2018 THSYN_RS27220 1f9f95e6641adf4c182871b428c814dd 759 Pfam PF00664 ABC transporter transmembrane region 194 463 3.3E-48 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS27220 1f9f95e6641adf4c182871b428c814dd 759 Gene3D G3DSA:3.40.50.300 506 755 9.9E-78 T 29-03-2018 THSYN_RS27220 1f9f95e6641adf4c182871b428c814dd 759 SUPERFAMILY SSF90123 178 502 6.28E-79 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS27220 1f9f95e6641adf4c182871b428c814dd 759 SMART SM00382 539 725 2.6E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS27220 1f9f95e6641adf4c182871b428c814dd 759 SUPERFAMILY SSF52540 509 749 3.94E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27220 1f9f95e6641adf4c182871b428c814dd 759 ProSitePatterns PS00211 ABC transporters family signature. 651 665 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS27220 1f9f95e6641adf4c182871b428c814dd 759 Pfam PF00005 ABC transporter 530 679 2.3E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 242 321 5.3E-27 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 Gene3D G3DSA:4.10.480.10 250 324 6.7E-29 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 72 223 4.5E-25 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 Gene3D G3DSA:3.40.50.700 55 249 2.0E-40 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 PIRSF PIRSF000310 15 340 3.1E-110 T 29-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 SUPERFAMILY SSF56770 62 321 7.2E-71 T 29-03-2018 THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 128 151 5.2E-59 T 29-03-2018 THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 247 265 5.2E-59 T 29-03-2018 THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 299 312 5.2E-59 T 29-03-2018 THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 271 297 5.2E-59 T 29-03-2018 THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 171 195 5.2E-59 T 29-03-2018 THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 229 246 5.2E-59 T 29-03-2018 THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 204 227 5.2E-59 T 29-03-2018 THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 57 79 5.2E-59 T 29-03-2018 THSYN_RS11700 9ac16f840edc72e04ba1540dda055a43 357 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 23 322 9.4E-99 T 29-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THSYN_RS06260 40f82619734ef80df2612cc9f13f6631 97 Gene3D G3DSA:3.30.460.10 2 96 1.2E-20 T 29-03-2018 THSYN_RS06260 40f82619734ef80df2612cc9f13f6631 97 SUPERFAMILY SSF81301 3 96 6.31E-20 T 29-03-2018 THSYN_RS06260 40f82619734ef80df2612cc9f13f6631 97 Pfam PF01909 Nucleotidyltransferase domain 20 85 3.2E-12 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS29645 04dd0a6263b3e219ee3fba9cd8c56a7f 474 Pfam PF04055 Radical SAM superfamily 125 279 1.4E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS29645 04dd0a6263b3e219ee3fba9cd8c56a7f 474 Pfam PF13186 Iron-sulfur cluster-binding domain 361 422 1.4E-9 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain THSYN_RS29645 04dd0a6263b3e219ee3fba9cd8c56a7f 474 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 26 86 2.4E-7 T 29-03-2018 IPR008792 Coenzyme PQQ synthesis D THSYN_RS29645 04dd0a6263b3e219ee3fba9cd8c56a7f 474 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 361 449 1.9E-11 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain THSYN_RS29645 04dd0a6263b3e219ee3fba9cd8c56a7f 474 SUPERFAMILY SSF102114 118 428 1.44E-60 T 29-03-2018 THSYN_RS29645 04dd0a6263b3e219ee3fba9cd8c56a7f 474 Gene3D G3DSA:3.20.20.70 113 440 1.1E-40 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS29645 04dd0a6263b3e219ee3fba9cd8c56a7f 474 Pfam PF13353 4Fe-4S single cluster domain 130 212 8.1E-6 T 29-03-2018 THSYN_RS05055 153a37e3c4ec8931e3527b2243f6a72d 91 Gene3D G3DSA:1.10.1220.10 1 60 7.4E-8 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS05055 153a37e3c4ec8931e3527b2243f6a72d 91 Pfam PF05534 HicB family 5 33 1.8E-6 T 29-03-2018 IPR008651 Uncharacterised protein family HicB THSYN_RS05055 153a37e3c4ec8931e3527b2243f6a72d 91 SUPERFAMILY SSF47598 2 39 1.26E-5 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 SUPERFAMILY SSF52540 320 548 2.28E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 Gene3D G3DSA:3.40.50.300 320 550 1.3E-44 T 29-03-2018 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 SUPERFAMILY SSF48452 10 130 1.39E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 SMART SM00028 183 216 0.015 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 SMART SM00028 81 114 2.5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 SMART SM00028 115 148 4.0E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 SMART SM00028 149 182 0.0084 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 SMART SM00028 255 288 17.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 SMART SM00028 13 46 63.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 SMART SM00028 47 80 250.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 Gene3D G3DSA:1.25.40.10 160 190 9.4E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 Gene3D G3DSA:1.25.40.10 88 124 1.4E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 Gene3D G3DSA:1.25.40.10 125 159 1.3E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 Pfam PF13469 Sulfotransferase family 324 513 9.8E-47 T 29-03-2018 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 Gene3D G3DSA:1.25.40.10 5 87 8.4E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 Pfam PF13432 Tetratricopeptide repeat 119 181 1.6E-9 T 29-03-2018 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 Pfam PF13432 Tetratricopeptide repeat 17 79 0.0089 T 29-03-2018 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 Pfam PF13181 Tetratricopeptide repeat 183 215 0.027 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 Pfam PF13181 Tetratricopeptide repeat 256 287 0.0064 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 SUPERFAMILY SSF48452 91 285 2.02E-34 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 Gene3D G3DSA:1.10.150.200 235 317 0.0026 T 29-03-2018 THSYN_RS24230 6fcb538ad4a2774e4e84280dfbdde2ba 582 Gene3D G3DSA:1.10.150.200 191 231 4.4E-6 T 29-03-2018 THSYN_RS09200 b1e7c20d62f89506a5ab056d5cc450e8 308 Pfam PF01545 Cation efflux family 19 220 6.3E-34 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THSYN_RS09200 b1e7c20d62f89506a5ab056d5cc450e8 308 Gene3D G3DSA:1.20.1510.10 15 220 3.8E-17 T 29-03-2018 THSYN_RS09200 b1e7c20d62f89506a5ab056d5cc450e8 308 SUPERFAMILY SSF161111 14 219 5.62E-31 T 29-03-2018 THSYN_RS12330 da311949b25e9e78620e3efb7fa43479 194 PIRSF PIRSF029681 6 194 3.6E-46 T 29-03-2018 IPR018550 Lipid A 3-O-deacylase-related THSYN_RS12330 da311949b25e9e78620e3efb7fa43479 194 Gene3D G3DSA:2.40.160.20 35 194 1.7E-29 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THSYN_RS12330 da311949b25e9e78620e3efb7fa43479 194 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 55 193 1.4E-33 T 29-03-2018 IPR018550 Lipid A 3-O-deacylase-related THSYN_RS28220 78c20810317614dfac6e0153a4a7f512 231 Gene3D G3DSA:1.10.10.60 54 148 3.7E-12 T 29-03-2018 THSYN_RS28220 78c20810317614dfac6e0153a4a7f512 231 Gene3D G3DSA:1.10.10.60 8 53 1.2E-17 T 29-03-2018 THSYN_RS28220 78c20810317614dfac6e0153a4a7f512 231 SUPERFAMILY SSF46689 9 86 5.99E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS28220 78c20810317614dfac6e0153a4a7f512 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 8.1E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THSYN_RS28220 78c20810317614dfac6e0153a4a7f512 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 8.1E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THSYN_RS28220 78c20810317614dfac6e0153a4a7f512 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 9.9E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 Gene3D G3DSA:3.30.950.10 342 467 2.3E-41 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 Gene3D G3DSA:3.30.160.110 106 146 1.5E-16 T 29-03-2018 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 297 330 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 207 2.6E-68 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 Pfam PF13241 Putative NAD(P)-binding 7 115 1.2E-25 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 SUPERFAMILY SSF53790 215 460 9.03E-83 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 PIRSF PIRSF036426 1 468 1.2E-195 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 Gene3D G3DSA:3.40.1010.10 216 341 6.6E-40 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 Gene3D G3DSA:1.10.8.210 151 208 3.5E-20 T 29-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 Pfam PF10414 Sirohaem synthase dimerisation region 150 207 1.6E-20 T 29-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 Hamap MF_01646 Siroheme synthase [cysG]. 1 461 52.523 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 217 452 9.3E-93 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 219 428 1.0E-51 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 SUPERFAMILY SSF51735 1 111 1.38E-23 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 SUPERFAMILY SSF75615 114 206 2.62E-25 T 29-03-2018 THSYN_RS17430 62a47c0799ca117d06661179272fc7bb 476 Gene3D G3DSA:3.40.50.720 1 105 2.8E-19 T 29-03-2018 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 Pfam PF05000 RNA polymerase Rpb1, domain 4 675 764 2.7E-19 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 Pfam PF04997 RNA polymerase Rpb1, domain 1 16 343 1.0E-89 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 Gene3D G3DSA:2.40.40.20 347 489 3.1E-40 T 29-03-2018 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 SUPERFAMILY SSF64484 16 945 0.0 T 29-03-2018 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 SUPERFAMILY SSF64484 1134 1363 0.0 T 29-03-2018 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 Pfam PF04998 RNA polymerase Rpb1, domain 5 767 1315 8.2E-77 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 Gene3D G3DSA:2.40.50.100 908 1022 2.3E-31 T 29-03-2018 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 645 3.1E-27 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 SMART SM00663 236 515 2.7E-179 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 Pfam PF00623 RNA polymerase Rpb1, domain 2 345 389 9.5E-8 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 Pfam PF00623 RNA polymerase Rpb1, domain 2 391 486 4.6E-27 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1367 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 Gene3D G3DSA:2.40.50.100 1155 1213 6.6E-14 T 29-03-2018 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1377 18.958 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS05725 a79deb0c2c425c23a0e010771e840e70 1403 Gene3D G3DSA:2.40.50.100 1029 1124 3.1E-10 T 29-03-2018 THSYN_RS23780 994b46ee0f273672035fd862405622e7 249 PIRSF PIRSF006779 5 248 7.8E-45 T 29-03-2018 IPR002747 SAM-dependent chlorinase/fluorinase THSYN_RS23780 994b46ee0f273672035fd862405622e7 249 Gene3D G3DSA:3.40.50.10790 7 154 4.3E-41 T 29-03-2018 THSYN_RS23780 994b46ee0f273672035fd862405622e7 249 SUPERFAMILY SSF101852 167 246 3.53E-15 T 29-03-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal THSYN_RS23780 994b46ee0f273672035fd862405622e7 249 SUPERFAMILY SSF102522 8 145 8.89E-40 T 29-03-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal THSYN_RS23780 994b46ee0f273672035fd862405622e7 249 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 9 245 1.3E-60 T 29-03-2018 IPR002747 SAM-dependent chlorinase/fluorinase THSYN_RS23780 994b46ee0f273672035fd862405622e7 249 Gene3D G3DSA:2.40.30.90 167 248 1.2E-15 T 29-03-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal THSYN_RS29060 24700bdc7910ae2b8edf5e9a16f174f5 418 Gene3D G3DSA:2.120.10.30 50 406 8.8E-10 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS29060 24700bdc7910ae2b8edf5e9a16f174f5 418 SUPERFAMILY SSF63829 27 254 5.36E-12 T 29-03-2018 THSYN_RS29060 24700bdc7910ae2b8edf5e9a16f174f5 418 Pfam PF16261 Domain of unknown function (DUF4915) 89 302 2.5E-15 T 29-03-2018 IPR017481 Conserved hypothetical protein CHP03032 THSYN_RS14590 9031141f327ff6559f1eea0c601896f8 333 Pfam PF13343 Bacterial extracellular solute-binding protein 91 300 3.6E-28 T 29-03-2018 THSYN_RS14590 9031141f327ff6559f1eea0c601896f8 333 Gene3D G3DSA:3.40.190.10 17 140 2.0E-4 T 29-03-2018 THSYN_RS14590 9031141f327ff6559f1eea0c601896f8 333 SUPERFAMILY SSF53850 23 324 4.69E-70 T 29-03-2018 THSYN_RS14590 9031141f327ff6559f1eea0c601896f8 333 Gene3D G3DSA:3.40.190.10 141 279 3.3E-28 T 29-03-2018 THSYN_RS14590 9031141f327ff6559f1eea0c601896f8 333 PIRSF PIRSF002825 7 332 1.7E-78 T 29-03-2018 IPR026045 Ferric binding protein THSYN_RS14995 616b4900685a51ada882308883e27cd4 886 Gene3D G3DSA:3.40.50.410 112 302 8.9E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS14995 616b4900685a51ada882308883e27cd4 886 SUPERFAMILY SSF53300 123 290 6.47E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS00130 26c817954a2fe5ee955f0ce26667c3d5 110 SUPERFAMILY SSF46785 14 108 1.23E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS00130 26c817954a2fe5ee955f0ce26667c3d5 110 Pfam PF01022 Bacterial regulatory protein, arsR family 33 77 4.4E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS00130 26c817954a2fe5ee955f0ce26667c3d5 110 Gene3D G3DSA:1.10.10.10 6 109 3.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS00130 26c817954a2fe5ee955f0ce26667c3d5 110 SMART SM00418 26 104 3.6E-25 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS00130 26c817954a2fe5ee955f0ce26667c3d5 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.3E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS00130 26c817954a2fe5ee955f0ce26667c3d5 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 58 1.3E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS00130 26c817954a2fe5ee955f0ce26667c3d5 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 28 43 1.3E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS00130 26c817954a2fe5ee955f0ce26667c3d5 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 1.3E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS11135 49315b2b95f1dbe4525d50f2a3a88590 744 SMART SM00487 204 404 2.4E-14 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS11135 49315b2b95f1dbe4525d50f2a3a88590 744 SUPERFAMILY SSF52540 512 609 8.72E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11135 49315b2b95f1dbe4525d50f2a3a88590 744 SUPERFAMILY SSF52540 222 449 8.72E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11135 49315b2b95f1dbe4525d50f2a3a88590 744 Gene3D G3DSA:3.40.50.300 405 623 9.2E-24 T 29-03-2018 THSYN_RS11135 49315b2b95f1dbe4525d50f2a3a88590 744 Gene3D G3DSA:3.40.50.300 200 393 2.7E-25 T 29-03-2018 THSYN_RS11135 49315b2b95f1dbe4525d50f2a3a88590 744 Pfam PF00271 Helicase conserved C-terminal domain 525 597 2.3E-7 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS11135 49315b2b95f1dbe4525d50f2a3a88590 744 TIGRFAM TIGR00595 priA: primosomal protein N' 231 740 1.8E-173 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 THSYN_RS11135 49315b2b95f1dbe4525d50f2a3a88590 744 Pfam PF04851 Type III restriction enzyme, res subunit 208 368 5.2E-10 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS11135 49315b2b95f1dbe4525d50f2a3a88590 744 SMART SM00490 501 598 1.2E-11 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS11135 49315b2b95f1dbe4525d50f2a3a88590 744 Hamap MF_00983 Probable primosomal protein N' [priA]. 3 743 24.166 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 THSYN_RS13935 52f437136636f0253c0e2a7272379c9c 599 Gene3D G3DSA:3.40.50.300 215 382 7.1E-5 T 29-03-2018 THSYN_RS13935 52f437136636f0253c0e2a7272379c9c 599 SUPERFAMILY SSF54211 420 593 5.69E-24 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS13935 52f437136636f0253c0e2a7272379c9c 599 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 552 570 5.2E-8 T 29-03-2018 THSYN_RS13935 52f437136636f0253c0e2a7272379c9c 599 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 228 247 5.2E-8 T 29-03-2018 THSYN_RS13935 52f437136636f0253c0e2a7272379c9c 599 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 529 548 5.2E-8 T 29-03-2018 THSYN_RS13935 52f437136636f0253c0e2a7272379c9c 599 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 499 518 5.2E-8 T 29-03-2018 THSYN_RS13935 52f437136636f0253c0e2a7272379c9c 599 Gene3D G3DSA:3.30.230.10 412 598 5.6E-21 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS13935 52f437136636f0253c0e2a7272379c9c 599 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 462 598 8.4E-9 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 THSYN_RS13935 52f437136636f0253c0e2a7272379c9c 599 Pfam PF13337 Putative ATP-dependent Lon protease 12 376 3.6E-143 T 29-03-2018 IPR014061 Conserved hypothetical protein CHP02688 THSYN_RS13935 52f437136636f0253c0e2a7272379c9c 599 SUPERFAMILY SSF52540 227 346 9.14E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13935 52f437136636f0253c0e2a7272379c9c 599 TIGRFAM TIGR02688 TIGR02688: TIGR02688 family protein 12 376 3.0E-106 T 29-03-2018 IPR014061 Conserved hypothetical protein CHP02688 THSYN_RS21325 97c3aad13121d4de502536006b397c94 408 Gene3D G3DSA:3.40.50.2000 193 387 5.3E-18 T 29-03-2018 THSYN_RS21325 97c3aad13121d4de502536006b397c94 408 SUPERFAMILY SSF53756 16 399 2.04E-25 T 29-03-2018 THSYN_RS21325 97c3aad13121d4de502536006b397c94 408 TIGRFAM TIGR03087 stp1: sugar transferase, PEP-CTERM/EpsH1 system associated 8 399 9.2E-151 T 29-03-2018 IPR017521 Sugar transferase, PEP-CTERM, Stp1 THSYN_RS21325 97c3aad13121d4de502536006b397c94 408 Pfam PF13692 Glycosyl transferases group 1 235 367 1.0E-26 T 29-03-2018 THSYN_RS32195 900751a6510698c770705b717986d318 274 Gene3D G3DSA:3.30.950.10 123 244 9.6E-22 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS32195 900751a6510698c770705b717986d318 274 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 77 110 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 THSYN_RS32195 900751a6510698c770705b717986d318 274 SUPERFAMILY SSF53790 1 252 5.23E-61 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS32195 900751a6510698c770705b717986d318 274 Gene3D G3DSA:3.40.1010.10 1 122 1.6E-30 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS32195 900751a6510698c770705b717986d318 274 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 THSYN_RS32195 900751a6510698c770705b717986d318 274 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 4 254 4.7E-94 T 29-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 THSYN_RS32195 900751a6510698c770705b717986d318 274 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 210 1.8E-41 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS04685 6fe4c4dbe9f23b460d81b1929ea085a2 82 Gene3D G3DSA:2.10.260.10 3 46 3.9E-14 T 29-03-2018 THSYN_RS04685 6fe4c4dbe9f23b460d81b1929ea085a2 82 SUPERFAMILY SSF89447 1 66 4.19E-13 T 29-03-2018 THSYN_RS04685 6fe4c4dbe9f23b460d81b1929ea085a2 82 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 37 7.2E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS04685 6fe4c4dbe9f23b460d81b1929ea085a2 82 SMART SM00966 6 52 2.7E-7 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS02445 b8d598cde2c19ba8db75a241c38acb75 403 Pfam PF13692 Glycosyl transferases group 1 183 318 8.6E-25 T 29-03-2018 THSYN_RS02445 b8d598cde2c19ba8db75a241c38acb75 403 SUPERFAMILY SSF53756 10 356 7.22E-56 T 29-03-2018 THSYN_RS02445 b8d598cde2c19ba8db75a241c38acb75 403 Gene3D G3DSA:3.40.50.2000 184 347 5.1E-35 T 29-03-2018 THSYN_RS02445 b8d598cde2c19ba8db75a241c38acb75 403 Gene3D G3DSA:3.40.50.2000 4 183 3.2E-4 T 29-03-2018 THSYN_RS08020 7f5fafee504076066a494491d08b033c 361 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 40 354 2.1E-134 T 29-03-2018 IPR017778 ABC transporter, urea, permease protein, UrtC THSYN_RS08020 7f5fafee504076066a494491d08b033c 361 Pfam PF02653 Branched-chain amino acid transport system / permease component 48 343 1.4E-40 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THSYN_RS08020 7f5fafee504076066a494491d08b033c 361 Gene3D G3DSA:1.10.3470.10 12 349 9.1E-28 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like THSYN_RS16840 cf2f9ae67399c1234bade4b854dea043 315 SUPERFAMILY SSF48452 259 303 1.93E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16840 cf2f9ae67399c1234bade4b854dea043 315 Gene3D G3DSA:1.25.40.10 250 306 4.7E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16840 cf2f9ae67399c1234bade4b854dea043 315 Pfam PF00535 Glycosyl transferase family 2 6 167 1.4E-25 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS16840 cf2f9ae67399c1234bade4b854dea043 315 Gene3D G3DSA:3.90.550.10 1 249 7.2E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS16840 cf2f9ae67399c1234bade4b854dea043 315 SUPERFAMILY SSF53448 2 213 6.47E-53 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS00230 168ec95942a5e177e36226aec4b74237 267 SUPERFAMILY SSF53474 4 266 1.18E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS00230 168ec95942a5e177e36226aec4b74237 267 Gene3D G3DSA:3.40.50.1820 2 267 1.7E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS00230 168ec95942a5e177e36226aec4b74237 267 PRINTS PR00412 Epoxide hydrolase signature 242 264 5.5E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS00230 168ec95942a5e177e36226aec4b74237 267 PRINTS PR00412 Epoxide hydrolase signature 101 114 5.5E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS00230 168ec95942a5e177e36226aec4b74237 267 PRINTS PR00412 Epoxide hydrolase signature 44 59 5.5E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS00230 168ec95942a5e177e36226aec4b74237 267 PRINTS PR00412 Epoxide hydrolase signature 87 100 5.5E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS00230 168ec95942a5e177e36226aec4b74237 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 1.6E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS00230 168ec95942a5e177e36226aec4b74237 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 1.6E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS00230 168ec95942a5e177e36226aec4b74237 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 1.6E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS00230 168ec95942a5e177e36226aec4b74237 267 Pfam PF00561 alpha/beta hydrolase fold 20 252 4.6E-25 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS20975 a30f29aced46136d2621df7d449f2ea2 147 Pfam PF09424 Yqey-like protein 3 145 1.7E-55 T 29-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial THSYN_RS20975 a30f29aced46136d2621df7d449f2ea2 147 SUPERFAMILY SSF89095 1 145 7.85E-42 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 THSYN_RS20975 a30f29aced46136d2621df7d449f2ea2 147 Gene3D G3DSA:1.10.1510.10 1 89 1.6E-32 T 29-03-2018 THSYN_RS20975 a30f29aced46136d2621df7d449f2ea2 147 Gene3D G3DSA:1.10.10.410 90 146 9.5E-17 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal THSYN_RS06580 1a14c47428e08c75babd712f8c58afe1 434 Pfam PF01609 Transposase DDE domain 107 345 7.3E-16 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS06580 1a14c47428e08c75babd712f8c58afe1 434 SUPERFAMILY SSF53098 71 350 5.23E-26 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS06580 1a14c47428e08c75babd712f8c58afe1 434 Gene3D G3DSA:3.90.350.10 147 330 1.3E-17 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS07675 2834c650225b80a03b3376475a927071 90 SMART SM00360 2 75 3.5E-28 T 29-03-2018 IPR000504 RNA recognition motif domain GO:0003676 THSYN_RS07675 2834c650225b80a03b3376475a927071 90 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 3 73 6.7E-25 T 29-03-2018 IPR000504 RNA recognition motif domain GO:0003676 THSYN_RS07675 2834c650225b80a03b3376475a927071 90 Gene3D G3DSA:3.30.70.330 1 88 9.7E-30 T 29-03-2018 THSYN_RS07675 2834c650225b80a03b3376475a927071 90 SUPERFAMILY SSF54928 2 88 3.63E-32 T 29-03-2018 IPR000504 RNA recognition motif domain GO:0003676 THSYN_RS12920 1a9886bd091f6ccc03dd5515e64b7dc1 476 Pfam PF01266 FAD dependent oxidoreductase 8 398 9.9E-17 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THSYN_RS12920 1a9886bd091f6ccc03dd5515e64b7dc1 476 SUPERFAMILY SSF51905 6 245 3.76E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS12920 1a9886bd091f6ccc03dd5515e64b7dc1 476 Gene3D G3DSA:3.50.50.60 1 357 4.6E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS14500 cb93a67dd4be4528e7919853d4c56a8a 46 Pfam PF01724 Domain of unknown function DUF29 3 40 4.7E-8 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS10910 bdf98d2c25b42e8869105dd8f2d64ba5 213 SUPERFAMILY SSF51366 4 203 5.65E-59 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THSYN_RS10910 bdf98d2c25b42e8869105dd8f2d64ba5 213 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 6 201 4.7E-48 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 THSYN_RS10910 bdf98d2c25b42e8869105dd8f2d64ba5 213 Gene3D G3DSA:3.20.20.70 3 207 1.9E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS10910 bdf98d2c25b42e8869105dd8f2d64ba5 213 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 4 206 42.181 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 THSYN_RS17410 5081bc508eb00444efb568b4c6fe8c35 217 SUPERFAMILY SSF81342 4 204 3.22E-29 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THSYN_RS17410 5081bc508eb00444efb568b4c6fe8c35 217 Pfam PF01292 Prokaryotic cytochrome b561 9 194 5.3E-21 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THSYN_RS17410 5081bc508eb00444efb568b4c6fe8c35 217 Gene3D G3DSA:1.20.950.20 1 213 1.6E-32 T 29-03-2018 THSYN_RS17410 5081bc508eb00444efb568b4c6fe8c35 217 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 157 179 6.6E-5 T 29-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 THSYN_RS17410 5081bc508eb00444efb568b4c6fe8c35 217 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 11 34 6.6E-5 T 29-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 THSYN_RS15750 cae7a38069b1be5df894d6bdf6f509c5 107 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 3 96 20.731 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family THSYN_RS15750 cae7a38069b1be5df894d6bdf6f509c5 107 SUPERFAMILY SSF82607 9 101 1.02E-31 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family THSYN_RS15750 cae7a38069b1be5df894d6bdf6f509c5 107 PIRSF PIRSF004555 2 107 1.8E-36 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family THSYN_RS15750 cae7a38069b1be5df894d6bdf6f509c5 107 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 103 8.7E-33 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family THSYN_RS15750 cae7a38069b1be5df894d6bdf6f509c5 107 Gene3D G3DSA:3.30.1310.10 1 107 2.4E-40 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family THSYN_RS15750 cae7a38069b1be5df894d6bdf6f509c5 107 Pfam PF02575 YbaB/EbfC DNA-binding family 10 97 7.8E-32 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family THSYN_RS07970 a0129b72bb354b19b2c670b2d474c417 112 SUPERFAMILY SSF101386 3 92 2.18E-27 T 29-03-2018 THSYN_RS07970 a0129b72bb354b19b2c670b2d474c417 112 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 2 88 22.707 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 THSYN_RS07970 a0129b72bb354b19b2c670b2d474c417 112 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 88 2.0E-34 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 THSYN_RS07970 a0129b72bb354b19b2c670b2d474c417 112 Gene3D G3DSA:1.10.287.1080 1 94 5.7E-27 T 29-03-2018 THSYN_RS07970 a0129b72bb354b19b2c670b2d474c417 112 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 6 91 4.6E-19 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 THSYN_RS00880 aa888f1ba73cfda946898a432f82cf0e 380 SUPERFAMILY SSF52266 260 370 2.38E-13 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain THSYN_RS00880 aa888f1ba73cfda946898a432f82cf0e 380 SUPERFAMILY SSF52266 125 215 2.38E-13 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain THSYN_RS00880 aa888f1ba73cfda946898a432f82cf0e 380 Gene3D G3DSA:3.40.50.1110 123 380 6.6E-18 T 29-03-2018 THSYN_RS05655 bae5d9f5b2cb8932be992e43e3ece80d 492 Gene3D G3DSA:2.40.160.60 24 490 5.8E-51 T 29-03-2018 THSYN_RS05655 bae5d9f5b2cb8932be992e43e3ece80d 492 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 16 449 1.1E-36 T 29-03-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) THSYN_RS05655 bae5d9f5b2cb8932be992e43e3ece80d 492 SUPERFAMILY SSF56935 25 152 6.11E-45 T 29-03-2018 THSYN_RS05655 bae5d9f5b2cb8932be992e43e3ece80d 492 SUPERFAMILY SSF56935 189 491 6.11E-45 T 29-03-2018 THSYN_RS03995 73d709a61718adde3347f2745898d6ad 392 Gene3D G3DSA:3.40.630.30 184 373 7.0E-35 T 29-03-2018 THSYN_RS03995 73d709a61718adde3347f2745898d6ad 392 Gene3D G3DSA:3.40.630.30 9 183 4.7E-10 T 29-03-2018 THSYN_RS03995 73d709a61718adde3347f2745898d6ad 392 SUPERFAMILY SSF55729 179 352 4.24E-37 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS03995 73d709a61718adde3347f2745898d6ad 392 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 10 378 5.6E-154 T 29-03-2018 IPR007434 Peptidogalycan biosysnthesis/recognition THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 SUPERFAMILY SSF52343 207 336 1.57E-40 T 29-03-2018 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 304 312 2.1E-20 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 198 207 2.1E-20 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 154 161 2.1E-20 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 214 233 2.1E-20 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 138 150 2.1E-20 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 239 248 2.1E-20 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 Pfam PF00970 Oxidoreductase FAD-binding domain 111 203 2.5E-15 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 SUPERFAMILY SSF63380 108 204 1.46E-26 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 Gene3D G3DSA:3.10.20.30 2 105 5.7E-20 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 19 87 5.5E-13 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 Gene3D G3DSA:3.40.50.80 206 339 1.1E-24 T 29-03-2018 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 45 53 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 SUPERFAMILY SSF54292 5 95 4.59E-23 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 Pfam PF00175 Oxidoreductase NAD-binding domain 215 316 4.3E-19 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THSYN_RS03415 becbfa56e8a3f41432094a5cebf89a92 348 Gene3D G3DSA:2.40.30.10 106 202 3.1E-23 T 29-03-2018 THSYN_RS32495 0a7ac69f42347f20fa0dce36162ede6d 175 Gene3D G3DSA:3.40.50.1820 2 157 1.5E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS32495 0a7ac69f42347f20fa0dce36162ede6d 175 SUPERFAMILY SSF53474 44 114 4.17E-7 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS32495 0a7ac69f42347f20fa0dce36162ede6d 175 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 4 175 5.9E-52 T 29-03-2018 IPR018712 Domain of unknown function DUF2235 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 Gene3D G3DSA:1.10.287.950 405 637 2.4E-36 T 29-03-2018 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 425 597 1.6E-26 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 SUPERFAMILY SSF103190 59 184 6.28E-13 T 29-03-2018 IPR029151 Periplasmic sensor domain-like THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 Gene3D G3DSA:3.30.450.20 207 282 8.0E-4 T 29-03-2018 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 Gene3D G3DSA:1.10.287.950 303 402 2.1E-6 T 29-03-2018 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 Pfam PF14827 Double sensory domain of two-component sensor kinase 41 272 7.8E-34 T 29-03-2018 IPR029150 Double Cache domain 3 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 Gene3D G3DSA:3.30.450.20 33 186 2.7E-8 T 29-03-2018 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 SMART SM00304 385 435 89.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 SMART SM00304 305 357 1.7E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 SUPERFAMILY SSF58104 325 634 1.7E-52 T 29-03-2018 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 2.4E-14 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 470 497 2.4E-14 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 499 528 2.4E-14 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 Pfam PF00672 HAMP domain 305 353 4.3E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS04380 14f4e259f5308cac04f0721135e2fc20 653 SMART SM00283 372 633 1.0E-39 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THSYN_RS20090 ad7e319eee6b8a79423c75fc471b0fe6 520 Pfam PF09820 Predicted AAA-ATPase 11 275 3.5E-87 T 29-03-2018 IPR018631 AAA-ATPase-like domain THSYN_RS20090 ad7e319eee6b8a79423c75fc471b0fe6 520 Pfam PF08011 PD-(D/E)XK nuclease superfamily 421 512 1.2E-19 T 29-03-2018 IPR012547 PD-(D/E)XK nuclease superfamily 9 THSYN_RS24190 01bd7533b2af11ee5590237bdbd56b7a 220 Gene3D G3DSA:2.30.130.40 9 122 2.0E-26 T 29-03-2018 THSYN_RS24190 01bd7533b2af11ee5590237bdbd56b7a 220 Gene3D G3DSA:1.10.4060.10 158 211 1.5E-6 T 29-03-2018 THSYN_RS24190 01bd7533b2af11ee5590237bdbd56b7a 220 SUPERFAMILY SSF88697 16 205 3.23E-40 T 29-03-2018 IPR015947 PUA-like domain THSYN_RS24190 01bd7533b2af11ee5590237bdbd56b7a 220 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 16 200 3.9E-22 T 29-03-2018 IPR003111 Lon, substrate-binding domain THSYN_RS24190 01bd7533b2af11ee5590237bdbd56b7a 220 SMART SM00464 16 207 1.1E-8 T 29-03-2018 IPR003111 Lon, substrate-binding domain THSYN_RS09230 d537fd9f5d47b77bc62eca213c1923c0 61 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 3 55 3.9E-20 T 29-03-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 THSYN_RS01525 e9cbbe2adda6ac96f8e53e1b959b56a6 548 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 8 440 1.6E-176 T 29-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 THSYN_RS01525 e9cbbe2adda6ac96f8e53e1b959b56a6 548 Pfam PF03109 ABC1 family 114 231 1.1E-34 T 29-03-2018 IPR004147 UbiB domain THSYN_RS01525 e9cbbe2adda6ac96f8e53e1b959b56a6 548 Gene3D G3DSA:3.30.200.20 103 244 1.6E-24 T 29-03-2018 THSYN_RS01525 e9cbbe2adda6ac96f8e53e1b959b56a6 548 Gene3D G3DSA:1.10.510.10 269 352 1.7E-4 T 29-03-2018 THSYN_RS01525 e9cbbe2adda6ac96f8e53e1b959b56a6 548 SUPERFAMILY SSF56112 193 432 4.05E-48 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS01525 e9cbbe2adda6ac96f8e53e1b959b56a6 548 SUPERFAMILY SSF56112 95 158 4.05E-48 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS01525 e9cbbe2adda6ac96f8e53e1b959b56a6 548 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 4 519 51.005 T 29-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 THSYN_RS31290 184cc59cb5dac45d83e6b50aa64484ce 46 PIRSF PIRSF002900 1 46 1.8E-14 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31290 184cc59cb5dac45d83e6b50aa64484ce 46 Pfam PF00556 Antenna complex alpha/beta subunit 11 46 3.5E-4 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31290 184cc59cb5dac45d83e6b50aa64484ce 46 PRINTS PR00674 Light harvesting protein B chain signature 8 28 2.4E-6 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31290 184cc59cb5dac45d83e6b50aa64484ce 46 PRINTS PR00674 Light harvesting protein B chain signature 28 45 2.4E-6 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31290 184cc59cb5dac45d83e6b50aa64484ce 46 SUPERFAMILY SSF56918 4 46 4.45E-12 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31290 184cc59cb5dac45d83e6b50aa64484ce 46 Gene3D G3DSA:1.20.5.250 5 46 1.1E-18 T 29-03-2018 THSYN_RS31265 184cc59cb5dac45d83e6b50aa64484ce 46 PIRSF PIRSF002900 1 46 1.8E-14 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31265 184cc59cb5dac45d83e6b50aa64484ce 46 Pfam PF00556 Antenna complex alpha/beta subunit 11 46 3.5E-4 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31265 184cc59cb5dac45d83e6b50aa64484ce 46 PRINTS PR00674 Light harvesting protein B chain signature 8 28 2.4E-6 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31265 184cc59cb5dac45d83e6b50aa64484ce 46 PRINTS PR00674 Light harvesting protein B chain signature 28 45 2.4E-6 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31265 184cc59cb5dac45d83e6b50aa64484ce 46 SUPERFAMILY SSF56918 4 46 4.45E-12 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31265 184cc59cb5dac45d83e6b50aa64484ce 46 Gene3D G3DSA:1.20.5.250 5 46 1.1E-18 T 29-03-2018 THSYN_RS31300 184cc59cb5dac45d83e6b50aa64484ce 46 PIRSF PIRSF002900 1 46 1.8E-14 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31300 184cc59cb5dac45d83e6b50aa64484ce 46 Pfam PF00556 Antenna complex alpha/beta subunit 11 46 3.5E-4 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31300 184cc59cb5dac45d83e6b50aa64484ce 46 PRINTS PR00674 Light harvesting protein B chain signature 8 28 2.4E-6 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31300 184cc59cb5dac45d83e6b50aa64484ce 46 PRINTS PR00674 Light harvesting protein B chain signature 28 45 2.4E-6 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31300 184cc59cb5dac45d83e6b50aa64484ce 46 SUPERFAMILY SSF56918 4 46 4.45E-12 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31300 184cc59cb5dac45d83e6b50aa64484ce 46 Gene3D G3DSA:1.20.5.250 5 46 1.1E-18 T 29-03-2018 THSYN_RS31255 184cc59cb5dac45d83e6b50aa64484ce 46 PIRSF PIRSF002900 1 46 1.8E-14 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31255 184cc59cb5dac45d83e6b50aa64484ce 46 Pfam PF00556 Antenna complex alpha/beta subunit 11 46 3.5E-4 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31255 184cc59cb5dac45d83e6b50aa64484ce 46 PRINTS PR00674 Light harvesting protein B chain signature 8 28 2.4E-6 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31255 184cc59cb5dac45d83e6b50aa64484ce 46 PRINTS PR00674 Light harvesting protein B chain signature 28 45 2.4E-6 T 29-03-2018 IPR002362 Antenna complex, beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31255 184cc59cb5dac45d83e6b50aa64484ce 46 SUPERFAMILY SSF56918 4 46 4.45E-12 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31255 184cc59cb5dac45d83e6b50aa64484ce 46 Gene3D G3DSA:1.20.5.250 5 46 1.1E-18 T 29-03-2018 THSYN_RS24490 0a4eaab90788d411d2419ea01f2af70b 104 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.5E-41 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24490 0a4eaab90788d411d2419ea01f2af70b 104 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 29-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS24490 0a4eaab90788d411d2419ea01f2af70b 104 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.5E-39 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24490 0a4eaab90788d411d2419ea01f2af70b 104 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 26.867 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24490 0a4eaab90788d411d2419ea01f2af70b 104 SUPERFAMILY SSF141091 1 102 9.68E-37 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS22650 1ef15acbc10d1a6c01d6ad612a165395 264 Gene3D G3DSA:3.30.70.20 141 184 6.7E-18 T 29-03-2018 THSYN_RS22650 1ef15acbc10d1a6c01d6ad612a165395 264 SUPERFAMILY SSF54862 57 248 2.83E-46 T 29-03-2018 THSYN_RS22650 1ef15acbc10d1a6c01d6ad612a165395 264 Pfam PF13247 4Fe-4S dicluster domain 122 218 6.7E-13 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS22650 1ef15acbc10d1a6c01d6ad612a165395 264 Gene3D G3DSA:3.30.70.20 71 140 3.9E-18 T 29-03-2018 THSYN_RS22650 1ef15acbc10d1a6c01d6ad612a165395 264 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 158 169 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS22650 1ef15acbc10d1a6c01d6ad612a165395 264 Gene3D G3DSA:3.30.70.20 185 263 1.1E-12 T 29-03-2018 THSYN_RS22650 1ef15acbc10d1a6c01d6ad612a165395 264 Gene3D G3DSA:3.30.70.20 44 70 0.062 T 29-03-2018 THSYN_RS16075 30e8e846b6d6fa2ee06659cfb9bf4ef7 509 Gene3D G3DSA:3.30.420.40 203 322 4.4E-32 T 29-03-2018 THSYN_RS16075 30e8e846b6d6fa2ee06659cfb9bf4ef7 509 Pfam PF02541 Ppx/GppA phosphatase family 231 505 9.3E-51 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 THSYN_RS16075 30e8e846b6d6fa2ee06659cfb9bf4ef7 509 SUPERFAMILY SSF53067 208 330 1.78E-26 T 29-03-2018 THSYN_RS16075 30e8e846b6d6fa2ee06659cfb9bf4ef7 509 Gene3D G3DSA:3.30.420.150 323 505 2.6E-42 T 29-03-2018 THSYN_RS16075 30e8e846b6d6fa2ee06659cfb9bf4ef7 509 SUPERFAMILY SSF53067 335 507 3.49E-37 T 29-03-2018 THSYN_RS02480 030c44c01e4edda9ef153b9925240d1f 443 SUPERFAMILY SSF52540 6 343 3.01E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02480 030c44c01e4edda9ef153b9925240d1f 443 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 11 350 2.0E-132 T 29-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 THSYN_RS02480 030c44c01e4edda9ef153b9925240d1f 443 Pfam PF00437 Type II/IV secretion system protein 122 253 2.8E-37 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THSYN_RS02480 030c44c01e4edda9ef153b9925240d1f 443 Gene3D G3DSA:3.30.450.90 10 107 3.8E-16 T 29-03-2018 THSYN_RS02480 030c44c01e4edda9ef153b9925240d1f 443 SMART SM00382 129 254 0.0054 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS02480 030c44c01e4edda9ef153b9925240d1f 443 Gene3D G3DSA:3.40.50.300 280 353 2.1E-12 T 29-03-2018 THSYN_RS02480 030c44c01e4edda9ef153b9925240d1f 443 Gene3D G3DSA:3.40.50.300 119 279 2.9E-25 T 29-03-2018 THSYN_RS29425 27629db0b21ca1917c85dc8a41932596 222 SUPERFAMILY SSF53448 13 162 1.97E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS29425 27629db0b21ca1917c85dc8a41932596 222 Gene3D G3DSA:3.90.550.10 3 204 8.6E-17 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS19040 9afafc6838b90b68ee87a763644b7b28 463 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 133 144 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS19040 9afafc6838b90b68ee87a763644b7b28 463 Pfam PF02754 Cysteine-rich domain 338 426 9.5E-11 T 29-03-2018 IPR004017 Cysteine-rich domain THSYN_RS19040 9afafc6838b90b68ee87a763644b7b28 463 Pfam PF13183 4Fe-4S dicluster domain 62 147 7.6E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS19040 9afafc6838b90b68ee87a763644b7b28 463 Gene3D G3DSA:1.10.1060.10 25 166 4.4E-20 T 29-03-2018 THSYN_RS19040 9afafc6838b90b68ee87a763644b7b28 463 SUPERFAMILY SSF46548 41 162 5.06E-19 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS20995 e18fa57fe551c978497495e2a784fed9 356 Gene3D G3DSA:3.40.50.1820 86 354 1.1E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS20995 e18fa57fe551c978497495e2a784fed9 356 PRINTS PR00412 Epoxide hydrolase signature 296 312 6.1E-11 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS20995 e18fa57fe551c978497495e2a784fed9 356 PRINTS PR00412 Epoxide hydrolase signature 117 135 6.1E-11 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS20995 e18fa57fe551c978497495e2a784fed9 356 PRINTS PR00412 Epoxide hydrolase signature 329 351 6.1E-11 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS20995 e18fa57fe551c978497495e2a784fed9 356 PRINTS PR00412 Epoxide hydrolase signature 137 152 6.1E-11 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS20995 e18fa57fe551c978497495e2a784fed9 356 PRINTS PR00111 Alpha/beta hydrolase fold signature 298 312 3.0E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS20995 e18fa57fe551c978497495e2a784fed9 356 PRINTS PR00111 Alpha/beta hydrolase fold signature 137 152 3.0E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS20995 e18fa57fe551c978497495e2a784fed9 356 PRINTS PR00111 Alpha/beta hydrolase fold signature 182 195 3.0E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS20995 e18fa57fe551c978497495e2a784fed9 356 PRINTS PR00111 Alpha/beta hydrolase fold signature 196 209 3.0E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS20995 e18fa57fe551c978497495e2a784fed9 356 SUPERFAMILY SSF53474 89 353 1.43E-59 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS20995 e18fa57fe551c978497495e2a784fed9 356 Pfam PF12146 Serine aminopeptidase, S33 112 340 3.7E-23 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 THSYN_RS07385 eeefa08e6d0a1921bbebc33ebbb171d3 145 Gene3D G3DSA:1.10.3680.10 5 144 1.4E-11 T 29-03-2018 IPR029024 TerB-like THSYN_RS07385 eeefa08e6d0a1921bbebc33ebbb171d3 145 SUPERFAMILY SSF158682 15 140 2.35E-12 T 29-03-2018 THSYN_RS20680 0662a262cca097ac33379d00ea12aaa1 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS20680 0662a262cca097ac33379d00ea12aaa1 55 Pfam PF00471 Ribosomal protein L33 7 53 5.3E-18 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20680 0662a262cca097ac33379d00ea12aaa1 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 1.1E-25 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20680 0662a262cca097ac33379d00ea12aaa1 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 14.862 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS20680 0662a262cca097ac33379d00ea12aaa1 55 SUPERFAMILY SSF57829 1 53 6.1E-19 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Gene3D G3DSA:1.25.40.20 277 342 4.8E-25 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Gene3D G3DSA:1.25.40.20 211 276 2.4E-21 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Gene3D G3DSA:1.25.40.20 409 472 8.0E-22 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Gene3D G3DSA:1.25.40.20 143 210 1.5E-20 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Gene3D G3DSA:1.25.40.20 343 408 7.4E-19 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Pfam PF12796 Ankyrin repeats (3 copies) 363 424 4.6E-10 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Pfam PF12796 Ankyrin repeats (3 copies) 536 627 2.7E-17 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Pfam PF12796 Ankyrin repeats (3 copies) 268 359 6.6E-17 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Pfam PF12796 Ankyrin repeats (3 copies) 61 127 9.8E-13 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Pfam PF12796 Ankyrin repeats (3 copies) 136 225 1.5E-15 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Pfam PF12796 Ankyrin repeats (3 copies) 433 524 3.1E-16 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Gene3D G3DSA:1.25.40.20 473 527 6.0E-16 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SUPERFAMILY SSF48403 59 415 6.36E-89 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SUPERFAMILY SSF48403 363 703 1.15E-81 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Pfam PF13857 Ankyrin repeats (many copies) 657 702 1.0E-7 T 29-03-2018 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Gene3D G3DSA:1.25.40.20 528 609 5.5E-25 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 531 560 0.0017 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 597 626 4.6E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 461 490 0.1 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 197 226 0.4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 663 692 6.4E-6 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 64 93 7.0E-4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 630 659 0.0026 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 296 325 1.3E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 362 391 0.0041 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 494 523 0.0023 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 329 358 0.052 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 130 159 0.0065 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 230 259 0.39 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 163 192 1.6E-4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 395 424 0.62 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 564 593 0.007 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 97 126 4.4E-4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 263 292 3.5E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 SMART SM00248 428 457 2.9E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Gene3D G3DSA:1.25.40.20 610 666 6.6E-22 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Gene3D G3DSA:1.25.40.20 27 142 2.3E-27 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS28620 b6bea379d3bc281fdaaa559f685981c8 727 Gene3D G3DSA:2.40.10.190 667 727 4.1E-9 T 29-03-2018 THSYN_RS24080 e1b057b20cad56a8dd55bdb48efac493 342 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 3 337 6.1E-125 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 THSYN_RS24080 e1b057b20cad56a8dd55bdb48efac493 342 Pfam PF02547 Queuosine biosynthesis protein 4 337 2.6E-125 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 THSYN_RS24080 e1b057b20cad56a8dd55bdb48efac493 342 SUPERFAMILY SSF111337 4 337 3.92E-130 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 THSYN_RS24080 e1b057b20cad56a8dd55bdb48efac493 342 Gene3D G3DSA:3.40.1780.10 172 338 9.1E-65 T 29-03-2018 THSYN_RS24080 e1b057b20cad56a8dd55bdb48efac493 342 Gene3D G3DSA:3.40.1780.10 1 112 1.0E-26 T 29-03-2018 THSYN_RS24080 e1b057b20cad56a8dd55bdb48efac493 342 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 338 45.112 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 THSYN_RS22470 79f48f7f0a4f2811b9ac025b33a7a95b 312 Pfam PF01933 Uncharacterised protein family UPF0052 11 258 7.5E-64 T 29-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 THSYN_RS22470 79f48f7f0a4f2811b9ac025b33a7a95b 312 Hamap MF_00973 Gluconeogenesis factor. 7 297 28.619 T 29-03-2018 IPR010119 Gluconeogenesis factor THSYN_RS22470 79f48f7f0a4f2811b9ac025b33a7a95b 312 Gene3D G3DSA:3.40.50.10680 87 299 9.6E-37 T 29-03-2018 THSYN_RS22470 79f48f7f0a4f2811b9ac025b33a7a95b 312 SUPERFAMILY SSF142338 10 292 8.63E-74 T 29-03-2018 THSYN_RS22470 79f48f7f0a4f2811b9ac025b33a7a95b 312 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 11 262 2.9E-83 T 29-03-2018 IPR010119 Gluconeogenesis factor THSYN_RS23540 cd014cfa19c54ea2c11a37b1c8c9b4f9 150 SUPERFAMILY SSF47413 94 147 5.2E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS23540 cd014cfa19c54ea2c11a37b1c8c9b4f9 150 Gene3D G3DSA:3.30.2020.10 2 87 1.4E-18 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS23540 cd014cfa19c54ea2c11a37b1c8c9b4f9 150 Gene3D G3DSA:1.10.260.40 95 149 4.7E-8 T 29-03-2018 THSYN_RS23540 cd014cfa19c54ea2c11a37b1c8c9b4f9 150 SUPERFAMILY SSF143880 4 87 7.72E-17 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS23540 cd014cfa19c54ea2c11a37b1c8c9b4f9 150 Pfam PF10387 Protein of unknown function (DUF2442) 10 81 1.2E-10 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS03540 f30594bcc7fce758dad9f0ba2abb47d0 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 358 24.187 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THSYN_RS03540 f30594bcc7fce758dad9f0ba2abb47d0 360 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 2.7E-5 T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THSYN_RS03540 f30594bcc7fce758dad9f0ba2abb47d0 360 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THSYN_RS03540 f30594bcc7fce758dad9f0ba2abb47d0 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 360 5.3E-135 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THSYN_RS03540 f30594bcc7fce758dad9f0ba2abb47d0 360 ProSitePatterns PS01348 MraY family signature 2. 189 200 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THSYN_RS03540 f30594bcc7fce758dad9f0ba2abb47d0 360 Pfam PF00953 Glycosyl transferase family 4 99 283 3.7E-37 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 THSYN_RS24925 3e5eaa66dc7be4edf0630babcd09eaee 276 SUPERFAMILY SSF48179 163 270 2.04E-35 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THSYN_RS24925 3e5eaa66dc7be4edf0630babcd09eaee 276 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 223 246 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 THSYN_RS24925 3e5eaa66dc7be4edf0630babcd09eaee 276 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 268 2.4E-77 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 THSYN_RS24925 3e5eaa66dc7be4edf0630babcd09eaee 276 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 267 1.7E-35 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 THSYN_RS24925 3e5eaa66dc7be4edf0630babcd09eaee 276 SUPERFAMILY SSF51735 6 161 4.15E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS24925 3e5eaa66dc7be4edf0630babcd09eaee 276 Gene3D G3DSA:3.40.50.720 1 165 3.8E-29 T 29-03-2018 THSYN_RS24925 3e5eaa66dc7be4edf0630babcd09eaee 276 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 100 5.8E-19 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal THSYN_RS24925 3e5eaa66dc7be4edf0630babcd09eaee 276 Gene3D G3DSA:1.10.3730.10 166 273 1.9E-39 T 29-03-2018 THSYN_RS24925 3e5eaa66dc7be4edf0630babcd09eaee 276 PIRSF PIRSF000193 3 271 3.8E-75 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 THSYN_RS24925 3e5eaa66dc7be4edf0630babcd09eaee 276 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 268 25.942 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 THSYN_RS24260 ec64b39d9eb525ced8483a08817cc527 477 SUPERFAMILY SSF56801 81 440 1.96E-18 T 29-03-2018 THSYN_RS24260 ec64b39d9eb525ced8483a08817cc527 477 Gene3D G3DSA:3.40.50.980 132 302 5.1E-11 T 29-03-2018 THSYN_RS09125 bae8053c0e1ad55c863b9bb08fb469cc 236 SUPERFAMILY SSF56024 12 137 2.86E-10 T 29-03-2018 THSYN_RS09125 bae8053c0e1ad55c863b9bb08fb469cc 236 Gene3D G3DSA:3.30.870.10 7 177 9.4E-14 T 29-03-2018 THSYN_RS09125 bae8053c0e1ad55c863b9bb08fb469cc 236 Pfam PF13091 PLD-like domain 15 130 1.4E-9 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THSYN_RS19835 d385365300d760ad0a2f33346ab3426e 205 Pfam PF00963 Cohesin domain 58 142 2.8E-5 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 THSYN_RS19835 d385365300d760ad0a2f33346ab3426e 205 SUPERFAMILY SSF49384 58 165 2.88E-11 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 THSYN_RS19835 d385365300d760ad0a2f33346ab3426e 205 Gene3D G3DSA:2.60.40.680 48 182 5.9E-17 T 29-03-2018 THSYN_RS25790 0d33db64e056a2fabbc2069b85a8e733 337 Pfam PF00490 Delta-aminolevulinic acid dehydratase 14 334 1.3E-139 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THSYN_RS25790 0d33db64e056a2fabbc2069b85a8e733 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 200 219 1.3E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THSYN_RS25790 0d33db64e056a2fabbc2069b85a8e733 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 279 294 1.3E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THSYN_RS25790 0d33db64e056a2fabbc2069b85a8e733 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 309 328 1.3E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THSYN_RS25790 0d33db64e056a2fabbc2069b85a8e733 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 131 145 1.3E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THSYN_RS25790 0d33db64e056a2fabbc2069b85a8e733 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 162 181 1.3E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THSYN_RS25790 0d33db64e056a2fabbc2069b85a8e733 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 254 270 1.3E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THSYN_RS25790 0d33db64e056a2fabbc2069b85a8e733 337 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 254 266 - T 29-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THSYN_RS25790 0d33db64e056a2fabbc2069b85a8e733 337 Gene3D G3DSA:3.20.20.70 2 337 5.3E-150 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS25790 0d33db64e056a2fabbc2069b85a8e733 337 SMART SM01004 11 335 7.6E-245 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THSYN_RS25790 0d33db64e056a2fabbc2069b85a8e733 337 SUPERFAMILY SSF51569 8 336 7.91E-144 T 29-03-2018 THSYN_RS25790 0d33db64e056a2fabbc2069b85a8e733 337 PIRSF PIRSF001415 4 337 1.0E-148 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THSYN_RS20735 9e8504b759fe3d1b90ca01774dd0ccc7 655 Pfam PF00350 Dynamin family 85 259 1.0E-6 T 29-03-2018 IPR022812 Dynamin superfamily THSYN_RS20735 9e8504b759fe3d1b90ca01774dd0ccc7 655 Gene3D G3DSA:3.40.50.300 13 427 2.9E-16 T 29-03-2018 THSYN_RS20735 9e8504b759fe3d1b90ca01774dd0ccc7 655 Gene3D G3DSA:1.10.490.50 461 542 8.5E-4 T 29-03-2018 THSYN_RS20735 9e8504b759fe3d1b90ca01774dd0ccc7 655 SUPERFAMILY SSF52540 41 144 1.83E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS20735 9e8504b759fe3d1b90ca01774dd0ccc7 655 SUPERFAMILY SSF52540 189 318 1.83E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06520 a48d65f94f44ba3ba74ddd7298a82547 205 Gene3D G3DSA:3.90.79.10 1 198 1.4E-28 T 29-03-2018 THSYN_RS06520 a48d65f94f44ba3ba74ddd7298a82547 205 SUPERFAMILY SSF55811 4 197 2.44E-32 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 THSYN_RS06520 a48d65f94f44ba3ba74ddd7298a82547 205 Pfam PF00293 NUDIX domain 48 134 1.6E-7 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THSYN_RS02730 f097121f73a391e8b2dc15fae9e642bb 296 SUPERFAMILY SSF52540 3 287 1.61E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02730 f097121f73a391e8b2dc15fae9e642bb 296 Gene3D G3DSA:3.40.50.300 1 291 9.4E-34 T 29-03-2018 THSYN_RS02730 f097121f73a391e8b2dc15fae9e642bb 296 PRINTS PR00478 Phosphoribulokinase family signature 12 29 5.4E-26 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS02730 f097121f73a391e8b2dc15fae9e642bb 296 PRINTS PR00478 Phosphoribulokinase family signature 164 181 5.4E-26 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS02730 f097121f73a391e8b2dc15fae9e642bb 296 PRINTS PR00478 Phosphoribulokinase family signature 126 144 5.4E-26 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS02730 f097121f73a391e8b2dc15fae9e642bb 296 PRINTS PR00478 Phosphoribulokinase family signature 182 205 5.4E-26 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THSYN_RS02730 f097121f73a391e8b2dc15fae9e642bb 296 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 214 8.7E-58 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 THSYN_RS18430 2b6357a37e9fc7b3ab234817487fe147 259 PIRSF PIRSF009120 1 259 2.3E-82 T 29-03-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 THSYN_RS18430 2b6357a37e9fc7b3ab234817487fe147 259 Gene3D G3DSA:3.60.20.10 2 239 1.3E-35 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS18430 2b6357a37e9fc7b3ab234817487fe147 259 SUPERFAMILY SSF56235 2 252 4.07E-28 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS32630 4e346326a7fd7b8eb029179b3b83c8f1 24 Hamap MF_00656 Coenzyme PQQ synthesis protein A [pqqA]. 2 24 10.629 T 29-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 THSYN_RS32630 4e346326a7fd7b8eb029179b3b83c8f1 24 TIGRFAM TIGR02107 PQQ_syn_pqqA: coenzyme PQQ precursor peptide PqqA 3 23 1.7E-11 T 29-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 THSYN_RS32630 4e346326a7fd7b8eb029179b3b83c8f1 24 Pfam PF08042 PqqA family 2 20 9.9E-9 T 29-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 THSYN_RS07705 5d1a5a93e93e3869878c5fe6e1324144 405 Pfam PF01555 DNA methylase 147 227 5.1E-19 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THSYN_RS07705 5d1a5a93e93e3869878c5fe6e1324144 405 Pfam PF01555 DNA methylase 69 144 1.5E-15 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THSYN_RS07705 5d1a5a93e93e3869878c5fe6e1324144 405 Gene3D G3DSA:3.40.50.150 136 250 6.3E-21 T 29-03-2018 THSYN_RS07705 5d1a5a93e93e3869878c5fe6e1324144 405 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 69 81 7.6E-16 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS07705 5d1a5a93e93e3869878c5fe6e1324144 405 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 195 209 7.6E-16 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS07705 5d1a5a93e93e3869878c5fe6e1324144 405 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 172 194 7.6E-16 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 THSYN_RS07705 5d1a5a93e93e3869878c5fe6e1324144 405 SUPERFAMILY SSF53335 45 243 2.75E-57 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS07705 5d1a5a93e93e3869878c5fe6e1324144 405 Gene3D G3DSA:3.40.50.150 44 135 9.4E-22 T 29-03-2018 THSYN_RS07705 5d1a5a93e93e3869878c5fe6e1324144 405 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 72 78 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS28545 c484eeef7670c438ce973c6964975521 375 PIRSF PIRSF006268 28 372 3.5E-82 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 THSYN_RS28545 c484eeef7670c438ce973c6964975521 375 Gene3D G3DSA:3.10.520.10 65 362 2.3E-43 T 29-03-2018 THSYN_RS28545 c484eeef7670c438ce973c6964975521 375 Pfam PF02424 ApbE family 63 350 1.9E-78 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 THSYN_RS28545 c484eeef7670c438ce973c6964975521 375 SUPERFAMILY SSF143631 56 368 5.23E-87 T 29-03-2018 IPR003374 ApbE-like domain THSYN_RS04280 a7d92041bfc51f7606b3bd0368146eb0 373 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 5.1E-44 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal THSYN_RS04280 a7d92041bfc51f7606b3bd0368146eb0 373 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 2.1E-77 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain THSYN_RS04280 a7d92041bfc51f7606b3bd0368146eb0 373 SMART SM01003 4 137 6.1E-71 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal THSYN_RS04280 a7d92041bfc51f7606b3bd0368146eb0 373 SUPERFAMILY SSF51735 137 303 4.51E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS04280 a7d92041bfc51f7606b3bd0368146eb0 373 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 369 2.3E-144 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 THSYN_RS04280 a7d92041bfc51f7606b3bd0368146eb0 373 SUPERFAMILY SSF52283 305 360 2.98E-62 T 29-03-2018 THSYN_RS04280 a7d92041bfc51f7606b3bd0368146eb0 373 SUPERFAMILY SSF52283 1 137 2.98E-62 T 29-03-2018 THSYN_RS04280 a7d92041bfc51f7606b3bd0368146eb0 373 PIRSF PIRSF000183 1 371 1.2E-140 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 THSYN_RS04280 a7d92041bfc51f7606b3bd0368146eb0 373 SMART SM01002 149 297 7.3E-79 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain THSYN_RS04280 a7d92041bfc51f7606b3bd0368146eb0 373 Gene3D G3DSA:3.40.50.720 205 371 4.2E-44 T 29-03-2018 THSYN_RS04280 a7d92041bfc51f7606b3bd0368146eb0 373 Gene3D G3DSA:3.40.50.720 1 198 5.2E-44 T 29-03-2018 THSYN_RS26795 c56ffcd9b6afdef59103af6292495119 288 SUPERFAMILY SSF53448 5 244 2.81E-39 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS26795 c56ffcd9b6afdef59103af6292495119 288 Gene3D G3DSA:3.90.550.10 2 256 2.5E-37 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS26795 c56ffcd9b6afdef59103af6292495119 288 Pfam PF00535 Glycosyl transferase family 2 16 152 3.7E-22 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS16085 c610a6158fe5c7e4640ffe198a2e7341 255 Pfam PF00994 Probable molybdopterin binding domain 16 168 7.3E-20 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS16085 c610a6158fe5c7e4640ffe198a2e7341 255 SMART SM00852 15 175 1.8E-26 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS16085 c610a6158fe5c7e4640ffe198a2e7341 255 SUPERFAMILY SSF53218 14 205 8.9E-28 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS16085 c610a6158fe5c7e4640ffe198a2e7341 255 Gene3D G3DSA:3.40.980.10 10 175 1.0E-32 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS21710 59c78a684f2cbe362a2414c5d993cc83 123 SUPERFAMILY SSF46785 49 101 1.23E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS21710 59c78a684f2cbe362a2414c5d993cc83 123 Gene3D G3DSA:1.10.10.10 9 109 9.6E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS16825 436b2782d7684e6f14cca5d6f149c411 427 Pfam PF01569 PAP2 superfamily 99 226 1.5E-23 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS16825 436b2782d7684e6f14cca5d6f149c411 427 Gene3D G3DSA:1.20.144.10 46 238 5.7E-22 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS16825 436b2782d7684e6f14cca5d6f149c411 427 SMART SM00014 97 222 5.4E-10 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS16825 436b2782d7684e6f14cca5d6f149c411 427 SUPERFAMILY SSF48317 16 231 1.44E-23 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS17755 ee182683b12773c80b32316298ec4f49 389 SUPERFAMILY SSF53756 89 352 6.85E-23 T 29-03-2018 THSYN_RS17755 ee182683b12773c80b32316298ec4f49 389 Gene3D G3DSA:3.40.50.2000 191 357 2.9E-20 T 29-03-2018 THSYN_RS17755 ee182683b12773c80b32316298ec4f49 389 Gene3D G3DSA:3.40.50.2300 74 179 0.095 T 29-03-2018 THSYN_RS17755 ee182683b12773c80b32316298ec4f49 389 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 15 177 2.2E-5 T 29-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 THSYN_RS23685 8cb7eef6718862ec9429df5fd829dc92 80 Pfam PF13488 Glycine zipper 35 74 4.9E-7 T 29-03-2018 THSYN_RS27515 f6966ab2dcb4ce5199cab0593ae673fb 279 SUPERFAMILY SSF55073 132 248 3.69E-39 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS27515 f6966ab2dcb4ce5199cab0593ae673fb 279 Gene3D G3DSA:3.30.70.270 117 251 3.2E-45 T 29-03-2018 THSYN_RS27515 f6966ab2dcb4ce5199cab0593ae673fb 279 SMART SM00267 105 264 1.2E-30 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS27515 f6966ab2dcb4ce5199cab0593ae673fb 279 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 131 247 4.0E-33 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS27515 f6966ab2dcb4ce5199cab0593ae673fb 279 Pfam PF00990 Diguanylate cyclase, GGDEF domain 132 247 7.3E-36 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS31005 6aa39b632dd8c51a83d6aab7a4bdaac3 476 Pfam PF01515 Phosphate acetyl/butaryl transferase 239 452 1.1E-47 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS31005 6aa39b632dd8c51a83d6aab7a4bdaac3 476 SUPERFAMILY SSF53659 167 456 4.11E-68 T 29-03-2018 THSYN_RS31005 6aa39b632dd8c51a83d6aab7a4bdaac3 476 Gene3D G3DSA:3.10.129.10 2 158 2.0E-32 T 29-03-2018 THSYN_RS31005 6aa39b632dd8c51a83d6aab7a4bdaac3 476 Gene3D G3DSA:3.40.50.10750 273 429 1.0E-45 T 29-03-2018 THSYN_RS31005 6aa39b632dd8c51a83d6aab7a4bdaac3 476 Pfam PF01575 MaoC like domain 19 115 2.5E-15 T 29-03-2018 IPR002539 MaoC-like domain THSYN_RS31005 6aa39b632dd8c51a83d6aab7a4bdaac3 476 SUPERFAMILY SSF54637 8 142 1.35E-35 T 29-03-2018 IPR029069 HotDog domain THSYN_RS28865 392f34e9397bf1585a3787447434aed4 689 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 145 154 - T 29-03-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site THSYN_RS28865 392f34e9397bf1585a3787447434aed4 689 Gene3D G3DSA:3.40.50.2020 550 689 3.0E-18 T 29-03-2018 THSYN_RS28865 392f34e9397bf1585a3787447434aed4 689 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 22 344 2.5E-66 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 THSYN_RS28865 392f34e9397bf1585a3787447434aed4 689 SUPERFAMILY SSF52540 67 349 1.05E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS28865 392f34e9397bf1585a3787447434aed4 689 Gene3D G3DSA:3.40.50.300 214 478 9.1E-30 T 29-03-2018 THSYN_RS28865 392f34e9397bf1585a3787447434aed4 689 SMART SM00487 19 220 7.9E-27 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS28865 392f34e9397bf1585a3787447434aed4 689 SMART SM00490 256 336 3.1E-15 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS28865 392f34e9397bf1585a3787447434aed4 689 Pfam PF00271 Helicase conserved C-terminal domain 243 335 5.7E-11 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS28865 392f34e9397bf1585a3787447434aed4 689 Pfam PF00270 DEAD/DEAH box helicase 26 193 1.6E-17 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS28865 392f34e9397bf1585a3787447434aed4 689 SUPERFAMILY SSF53271 555 684 2.49E-13 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like THSYN_RS28865 392f34e9397bf1585a3787447434aed4 689 Gene3D G3DSA:3.40.50.300 6 206 3.4E-30 T 29-03-2018 THSYN_RS08380 9daa3cbb62b526ae1932a2bd6cc30694 313 SUPERFAMILY SSF52172 83 200 8.82E-32 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS08380 9daa3cbb62b526ae1932a2bd6cc30694 313 Gene3D G3DSA:1.10.10.10 199 312 1.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS08380 9daa3cbb62b526ae1932a2bd6cc30694 313 SMART SM00862 230 305 6.0E-17 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS08380 9daa3cbb62b526ae1932a2bd6cc30694 313 SMART SM00448 84 192 4.8E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08380 9daa3cbb62b526ae1932a2bd6cc30694 313 Pfam PF00072 Response regulator receiver domain 87 192 1.2E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08380 9daa3cbb62b526ae1932a2bd6cc30694 313 SUPERFAMILY SSF46894 203 306 2.66E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS08380 9daa3cbb62b526ae1932a2bd6cc30694 313 Gene3D G3DSA:3.40.50.2300 66 198 7.0E-31 T 29-03-2018 THSYN_RS08380 9daa3cbb62b526ae1932a2bd6cc30694 313 Pfam PF00486 Transcriptional regulatory protein, C terminal 230 305 4.0E-14 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS10685 ed08590d82fcf44677818b664ad8974c 389 Pfam PF13676 TIR domain 13 114 1.1E-15 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS10685 ed08590d82fcf44677818b664ad8974c 389 SUPERFAMILY SSF52540 192 325 2.3E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10685 ed08590d82fcf44677818b664ad8974c 389 Pfam PF13191 AAA ATPase domain 199 331 5.2E-9 T 29-03-2018 THSYN_RS10685 ed08590d82fcf44677818b664ad8974c 389 Gene3D G3DSA:3.40.50.10140 2 187 1.1E-13 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS10685 ed08590d82fcf44677818b664ad8974c 389 SMART SM00255 9 196 0.0067 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS10685 ed08590d82fcf44677818b664ad8974c 389 Gene3D G3DSA:3.40.50.300 188 339 1.1E-10 T 29-03-2018 THSYN_RS10685 ed08590d82fcf44677818b664ad8974c 389 SUPERFAMILY SSF52200 10 152 1.31E-15 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS08950 7c0e9f2c4261f34353565d4221571eff 64 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS08950 7c0e9f2c4261f34353565d4221571eff 64 Gene3D G3DSA:3.30.70.20 1 29 5.4E-6 T 29-03-2018 THSYN_RS08950 7c0e9f2c4261f34353565d4221571eff 64 SUPERFAMILY SSF54862 6 58 6.4E-13 T 29-03-2018 THSYN_RS08950 7c0e9f2c4261f34353565d4221571eff 64 Pfam PF00037 4Fe-4S binding domain 5 25 1.2E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS08950 7c0e9f2c4261f34353565d4221571eff 64 Gene3D G3DSA:3.30.70.20 30 63 0.0012 T 29-03-2018 THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 SUPERFAMILY SSF49299 152 244 5.23E-8 T 29-03-2018 IPR000601 PKD domain THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 Gene3D G3DSA:2.60.40.10 260 337 3.7E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 SUPERFAMILY SSF101898 1095 1297 3.14E-5 T 29-03-2018 THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 Gene3D G3DSA:2.60.40.10 228 259 0.086 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 Gene3D G3DSA:2.60.40.10 147 227 6.5E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 SUPERFAMILY SSF49313 247 341 1.53E-5 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 Gene3D G3DSA:2.60.40.10 338 430 2.7E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 SUPERFAMILY SSF49452 572 643 1.02E-10 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 Pfam PF13620 Carboxypeptidase regulatory-like domain 576 640 2.2E-10 T 29-03-2018 THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 SUPERFAMILY SSF49313 344 431 2.35E-7 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 Gene3D G3DSA:2.60.40.1120 576 648 2.8E-10 T 29-03-2018 THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 SMART SM00089 359 431 7.0 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 SMART SM00089 277 340 3.7 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS29920 53983e45e40aab1f4c719b008350870d 1315 SMART SM00089 164 240 1.0E-4 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS28580 b793d85f21b6a9a341a8813a5e75f4d7 91 SUPERFAMILY SSF47598 3 79 1.45E-20 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS28580 b793d85f21b6a9a341a8813a5e75f4d7 91 Gene3D G3DSA:1.20.890.30 50 85 3.9E-10 T 29-03-2018 THSYN_RS28580 b793d85f21b6a9a341a8813a5e75f4d7 91 Pfam PF08681 Protein of unknown function (DUF1778) 6 83 1.0E-24 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 THSYN_RS28580 b793d85f21b6a9a341a8813a5e75f4d7 91 Gene3D G3DSA:1.10.1220.10 3 46 1.7E-16 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS10185 4775ac2996cffb48a3227dfc123bd4b3 187 Pfam PF02622 Uncharacterized ACR, COG1678 16 174 3.0E-49 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 THSYN_RS10185 4775ac2996cffb48a3227dfc123bd4b3 187 Gene3D G3DSA:3.30.70.1300 46 119 7.0E-31 T 29-03-2018 THSYN_RS10185 4775ac2996cffb48a3227dfc123bd4b3 187 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 5 187 39.011 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 THSYN_RS10185 4775ac2996cffb48a3227dfc123bd4b3 187 SUPERFAMILY SSF143456 6 187 3.92E-65 T 29-03-2018 THSYN_RS10185 4775ac2996cffb48a3227dfc123bd4b3 187 Gene3D G3DSA:3.40.1740.10 120 179 1.2E-7 T 29-03-2018 THSYN_RS22850 66f74a343d473278d47ea80589fe89de 185 SUPERFAMILY SSF56436 1 105 7.77E-22 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS22850 66f74a343d473278d47ea80589fe89de 185 Gene3D G3DSA:3.90.1580.10 21 140 9.7E-19 T 29-03-2018 THSYN_RS22850 66f74a343d473278d47ea80589fe89de 185 Pfam PF03781 Sulfatase-modifying factor enzyme 1 1 77 1.1E-17 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS20025 02aff8989aa83474780828eee2ae8d8f 230 SUPERFAMILY SSF52317 1 190 2.92E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS20025 02aff8989aa83474780828eee2ae8d8f 230 Pfam PF00117 Glutamine amidotransferase class-I 22 180 4.7E-14 T 29-03-2018 IPR017926 Glutamine amidotransferase THSYN_RS20025 02aff8989aa83474780828eee2ae8d8f 230 Gene3D G3DSA:3.40.50.880 1 229 3.3E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS05625 bd791a38aa04d94275b90ae25506b22e 484 Gene3D G3DSA:2.40.50.140 32 118 3.0E-29 T 29-03-2018 THSYN_RS05625 bd791a38aa04d94275b90ae25506b22e 484 SUPERFAMILY SSF50249 39 119 2.32E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS05625 bd791a38aa04d94275b90ae25506b22e 484 SMART SM00316 37 114 3.3E-11 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS05625 bd791a38aa04d94275b90ae25506b22e 484 Pfam PF10150 Ribonuclease E/G family 116 388 9.6E-101 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 THSYN_RS05625 bd791a38aa04d94275b90ae25506b22e 484 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 421 6.3E-154 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 THSYN_RS05625 bd791a38aa04d94275b90ae25506b22e 484 Pfam PF00575 S1 RNA binding domain 38 101 8.9E-8 T 29-03-2018 IPR003029 S1 domain GO:0003676 THSYN_RS14940 2c27b2b75b42edcae95fbdeab6cb8e4d 133 Gene3D G3DSA:1.20.5.340 24 88 0.0036 T 29-03-2018 THSYN_RS14940 2c27b2b75b42edcae95fbdeab6cb8e4d 133 Gene3D G3DSA:1.20.5.730 96 133 0.056 T 29-03-2018 THSYN_RS07600 c716fea4ab9a1e541e3a53bf538312f4 126 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 1 116 7.2E-23 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07600 c716fea4ab9a1e541e3a53bf538312f4 126 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 4 122 1.2E-31 T 29-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07600 c716fea4ab9a1e541e3a53bf538312f4 126 PIRSF PIRSF000178 1 124 5.4E-24 T 29-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07600 c716fea4ab9a1e541e3a53bf538312f4 126 SUPERFAMILY SSF81343 2 122 3.71E-24 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07600 c716fea4ab9a1e541e3a53bf538312f4 126 Gene3D G3DSA:1.20.1300.10 13 126 3.7E-21 T 29-03-2018 THSYN_RS14565 0b1fe46dc55450e15bd6bfc4a9568e1b 253 Gene3D G3DSA:3.40.30.10 102 239 1.7E-21 T 29-03-2018 THSYN_RS14565 0b1fe46dc55450e15bd6bfc4a9568e1b 253 SUPERFAMILY SSF54423 27 81 1.8E-12 T 29-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal THSYN_RS14565 0b1fe46dc55450e15bd6bfc4a9568e1b 253 Gene3D G3DSA:3.10.450.70 21 82 5.0E-22 T 29-03-2018 THSYN_RS14565 0b1fe46dc55450e15bd6bfc4a9568e1b 253 SUPERFAMILY SSF52833 107 237 1.03E-31 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS14565 0b1fe46dc55450e15bd6bfc4a9568e1b 253 Pfam PF10411 Disulfide bond isomerase protein N-terminus 28 81 1.6E-20 T 29-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal THSYN_RS14565 0b1fe46dc55450e15bd6bfc4a9568e1b 253 Pfam PF13098 Thioredoxin-like domain 111 237 2.3E-21 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS32655 25e8dd50cc96ccc1055c66422426dc08 707 Gene3D G3DSA:3.20.110.10 227 330 5.7E-13 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain THSYN_RS32655 25e8dd50cc96ccc1055c66422426dc08 707 SUPERFAMILY SSF88713 134 322 2.22E-27 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS32655 25e8dd50cc96ccc1055c66422426dc08 707 SUPERFAMILY SSF88713 360 559 2.22E-27 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS32655 25e8dd50cc96ccc1055c66422426dc08 707 Gene3D G3DSA:3.20.110.10 133 226 1.1E-8 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain THSYN_RS32655 25e8dd50cc96ccc1055c66422426dc08 707 Gene3D G3DSA:3.20.110.10 400 489 5.0E-6 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain THSYN_RS32655 25e8dd50cc96ccc1055c66422426dc08 707 Pfam PF03065 Glycosyl hydrolase family 57 238 313 3.0E-10 T 29-03-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 THSYN_RS07005 6c78ec0d751db36d5eb25e6664090330 380 Gene3D G3DSA:3.90.1150.10 243 373 1.1E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS07005 6c78ec0d751db36d5eb25e6664090330 380 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 195 214 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site THSYN_RS07005 6c78ec0d751db36d5eb25e6664090330 380 PIRSF PIRSF005572 2 379 1.7E-124 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 THSYN_RS07005 6c78ec0d751db36d5eb25e6664090330 380 Pfam PF00266 Aminotransferase class-V 5 365 2.7E-70 T 29-03-2018 IPR000192 Aminotransferase class V domain THSYN_RS07005 6c78ec0d751db36d5eb25e6664090330 380 Gene3D G3DSA:3.40.640.10 13 242 1.7E-56 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS07005 6c78ec0d751db36d5eb25e6664090330 380 SUPERFAMILY SSF53383 3 373 4.03E-97 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS09845 de0cfb6cc5445f22faa235859e1b9d1f 901 Gene3D G3DSA:3.40.50.150 196 478 1.1E-65 T 29-03-2018 THSYN_RS09845 de0cfb6cc5445f22faa235859e1b9d1f 901 Pfam PF02384 N-6 DNA Methylase 176 482 7.2E-103 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS09845 de0cfb6cc5445f22faa235859e1b9d1f 901 Pfam PF12161 HsdM N-terminal domain 11 160 9.1E-32 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS09845 de0cfb6cc5445f22faa235859e1b9d1f 901 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 333 357 4.6E-22 T 29-03-2018 THSYN_RS09845 de0cfb6cc5445f22faa235859e1b9d1f 901 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 198 214 4.6E-22 T 29-03-2018 THSYN_RS09845 de0cfb6cc5445f22faa235859e1b9d1f 901 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 299 311 4.6E-22 T 29-03-2018 THSYN_RS09845 de0cfb6cc5445f22faa235859e1b9d1f 901 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 222 236 4.6E-22 T 29-03-2018 THSYN_RS09845 de0cfb6cc5445f22faa235859e1b9d1f 901 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 11 489 3.9E-73 T 29-03-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 THSYN_RS09845 de0cfb6cc5445f22faa235859e1b9d1f 901 SUPERFAMILY SSF53335 78 507 2.15E-131 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS09845 de0cfb6cc5445f22faa235859e1b9d1f 901 SUPERFAMILY SSF53335 9 48 2.15E-131 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 SUPERFAMILY SSF50249 347 439 5.83E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 SUPERFAMILY SSF50249 102 185 4.7E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 1.3E-215 T 29-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 SUPERFAMILY SSF50249 433 532 2.24E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 PIRSF PIRSF002111 385 548 1.3E-38 T 29-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 PIRSF PIRSF002111 1 386 1.6E-174 T 29-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 SUPERFAMILY SSF50249 2 112 5.52E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 SUPERFAMILY SSF50249 255 354 1.04E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 PRINTS PR00681 Ribosomal protein S1 signature 290 309 3.7E-88 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 PRINTS PR00681 Ribosomal protein S1 signature 330 348 3.7E-88 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 PRINTS PR00681 Ribosomal protein S1 signature 108 124 3.7E-88 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 PRINTS PR00681 Ribosomal protein S1 signature 155 175 3.7E-88 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 PRINTS PR00681 Ribosomal protein S1 signature 21 39 3.7E-88 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 PRINTS PR00681 Ribosomal protein S1 signature 84 103 3.7E-88 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 PRINTS PR00681 Ribosomal protein S1 signature 39 53 3.7E-88 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 PRINTS PR00681 Ribosomal protein S1 signature 212 233 3.7E-88 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 PRINTS PR00681 Ribosomal protein S1 signature 126 143 3.7E-88 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 Pfam PF00575 S1 RNA binding domain 189 260 2.9E-21 T 29-03-2018 IPR003029 S1 domain GO:0003676 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 Pfam PF00575 S1 RNA binding domain 448 520 2.4E-14 T 29-03-2018 IPR003029 S1 domain GO:0003676 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 Pfam PF00575 S1 RNA binding domain 361 434 6.9E-20 T 29-03-2018 IPR003029 S1 domain GO:0003676 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 Pfam PF00575 S1 RNA binding domain 102 171 9.4E-13 T 29-03-2018 IPR003029 S1 domain GO:0003676 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 Pfam PF00575 S1 RNA binding domain 276 347 2.7E-20 T 29-03-2018 IPR003029 S1 domain GO:0003676 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 SMART SM00316 103 171 7.5E-10 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 SMART SM00316 362 434 1.7E-21 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 SMART SM00316 275 347 7.2E-26 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 SMART SM00316 19 87 2.4E-7 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 SMART SM00316 190 260 1.3E-27 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 SMART SM00316 449 520 2.5E-19 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 Gene3D G3DSA:2.40.50.140 1 91 1.3E-9 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 Gene3D G3DSA:2.40.50.140 445 526 2.7E-18 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 Gene3D G3DSA:2.40.50.140 182 266 6.1E-26 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 Gene3D G3DSA:2.40.50.140 94 177 2.1E-8 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 SUPERFAMILY SSF50249 189 275 2.16E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 Gene3D G3DSA:2.40.50.140 275 348 1.4E-26 T 29-03-2018 THSYN_RS04080 b75a76efb82ae738ede91f2a414169c6 559 Gene3D G3DSA:2.40.50.140 361 435 1.0E-21 T 29-03-2018 THSYN_RS09770 222b64d37876b5ebb3aaa7dd3094d084 325 Pfam PF04055 Radical SAM superfamily 67 215 4.9E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS09770 222b64d37876b5ebb3aaa7dd3094d084 325 SUPERFAMILY SSF102114 37 302 6.08E-32 T 29-03-2018 THSYN_RS09770 222b64d37876b5ebb3aaa7dd3094d084 325 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 4 325 2.3E-116 T 29-03-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme THSYN_RS09770 222b64d37876b5ebb3aaa7dd3094d084 325 Gene3D G3DSA:3.20.20.70 55 293 2.9E-21 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS09770 222b64d37876b5ebb3aaa7dd3094d084 325 PIRSF PIRSF004869 1 301 4.6E-87 T 29-03-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted THSYN_RS02250 8999d3b168a331e25afdecdc7d00d689 1049 Gene3D G3DSA:3.40.50.300 279 492 1.5E-27 T 29-03-2018 THSYN_RS02250 8999d3b168a331e25afdecdc7d00d689 1049 SMART SM00487 300 501 2.5E-21 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS02250 8999d3b168a331e25afdecdc7d00d689 1049 SMART SM00490 611 695 3.8E-12 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS02250 8999d3b168a331e25afdecdc7d00d689 1049 SUPERFAMILY SSF52540 287 484 4.14E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02250 8999d3b168a331e25afdecdc7d00d689 1049 Pfam PF00270 DEAD/DEAH box helicase 308 462 9.4E-19 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS02250 8999d3b168a331e25afdecdc7d00d689 1049 Pfam PF00271 Helicase conserved C-terminal domain 618 695 6.2E-6 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS02250 8999d3b168a331e25afdecdc7d00d689 1049 SUPERFAMILY SSF52540 522 710 1.73E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS33110 a5b1a39e095fc64f2bb145f589389ce6 339 Gene3D G3DSA:3.40.190.80 218 336 4.5E-15 T 29-03-2018 THSYN_RS33110 a5b1a39e095fc64f2bb145f589389ce6 339 SUPERFAMILY SSF56655 76 337 5.63E-56 T 29-03-2018 THSYN_RS33110 a5b1a39e095fc64f2bb145f589389ce6 339 PRINTS PR00377 Inositol monophosphatase superfamily signature 202 225 1.2E-20 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS33110 a5b1a39e095fc64f2bb145f589389ce6 339 PRINTS PR00377 Inositol monophosphatase superfamily signature 279 303 1.2E-20 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS33110 a5b1a39e095fc64f2bb145f589389ce6 339 PRINTS PR00377 Inositol monophosphatase superfamily signature 110 130 1.2E-20 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS33110 a5b1a39e095fc64f2bb145f589389ce6 339 PRINTS PR00377 Inositol monophosphatase superfamily signature 153 169 1.2E-20 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS33110 a5b1a39e095fc64f2bb145f589389ce6 339 PRINTS PR00377 Inositol monophosphatase superfamily signature 248 269 1.2E-20 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS33110 a5b1a39e095fc64f2bb145f589389ce6 339 Gene3D G3DSA:3.30.540.10 66 217 2.2E-35 T 29-03-2018 THSYN_RS33110 a5b1a39e095fc64f2bb145f589389ce6 339 Pfam PF00459 Inositol monophosphatase family 74 312 1.6E-41 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS16255 14167b72690a382d93b7a2dea46909b8 75 Pfam PF00072 Response regulator receiver domain 13 66 2.2E-7 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS16255 14167b72690a382d93b7a2dea46909b8 75 SUPERFAMILY SSF52172 9 66 8.68E-13 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS16255 14167b72690a382d93b7a2dea46909b8 75 Gene3D G3DSA:3.40.50.2300 6 69 6.2E-12 T 29-03-2018 THSYN_RS21510 e7d0fde45434381080c2cc8231dd08c3 869 Gene3D G3DSA:3.30.450.20 571 714 1.5E-18 T 29-03-2018 THSYN_RS21510 e7d0fde45434381080c2cc8231dd08c3 869 SUPERFAMILY SSF55785 431 564 4.04E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS21510 e7d0fde45434381080c2cc8231dd08c3 869 SMART SM00091 443 513 3.8E-9 T 29-03-2018 IPR000014 PAS domain THSYN_RS21510 e7d0fde45434381080c2cc8231dd08c3 869 SMART SM00091 571 638 1.6E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS21510 e7d0fde45434381080c2cc8231dd08c3 869 SUPERFAMILY SSF55785 566 682 4.19E-16 T 29-03-2018 IPR000014 PAS domain THSYN_RS21510 e7d0fde45434381080c2cc8231dd08c3 869 SMART SM00304 366 422 0.0044 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS21510 e7d0fde45434381080c2cc8231dd08c3 869 Pfam PF13188 PAS domain 443 483 2.8E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS21510 e7d0fde45434381080c2cc8231dd08c3 869 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 568 690 6.4E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS21510 e7d0fde45434381080c2cc8231dd08c3 869 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 439 572 2.9E-11 T 29-03-2018 IPR000014 PAS domain THSYN_RS21510 e7d0fde45434381080c2cc8231dd08c3 869 Pfam PF13426 PAS domain 582 683 2.2E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS21510 e7d0fde45434381080c2cc8231dd08c3 869 Gene3D G3DSA:3.30.450.20 414 570 2.1E-21 T 29-03-2018 THSYN_RS22035 cda9d4a8a7d6a6e46b8ec4e0b771a5c0 294 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS22035 cda9d4a8a7d6a6e46b8ec4e0b771a5c0 294 SUPERFAMILY SSF46934 1 55 1.28E-17 T 29-03-2018 IPR009060 UBA-like GO:0005515 THSYN_RS22035 cda9d4a8a7d6a6e46b8ec4e0b771a5c0 294 Gene3D G3DSA:3.30.479.20 57 159 1.3E-23 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS22035 cda9d4a8a7d6a6e46b8ec4e0b771a5c0 294 Gene3D G3DSA:3.30.479.20 160 291 1.1E-48 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS22035 cda9d4a8a7d6a6e46b8ec4e0b771a5c0 294 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 293 4.0E-99 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS22035 cda9d4a8a7d6a6e46b8ec4e0b771a5c0 294 Gene3D G3DSA:1.10.8.10 1 55 1.2E-21 T 29-03-2018 THSYN_RS22035 cda9d4a8a7d6a6e46b8ec4e0b771a5c0 294 SUPERFAMILY SSF54713 55 149 9.16E-23 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS22035 cda9d4a8a7d6a6e46b8ec4e0b771a5c0 294 SUPERFAMILY SSF54713 154 292 4.06E-50 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS22035 cda9d4a8a7d6a6e46b8ec4e0b771a5c0 294 ProSitePatterns PS01127 Elongation factor Ts signature 2. 76 86 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS22035 cda9d4a8a7d6a6e46b8ec4e0b771a5c0 294 Pfam PF00889 Elongation factor TS 72 275 3.6E-66 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS22035 cda9d4a8a7d6a6e46b8ec4e0b771a5c0 294 Hamap MF_00050 Elongation factor Ts [tsf]. 1 293 76.714 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THSYN_RS02985 266e891ab0dc48ba2808a00d3779d3bb 443 Pfam PF00999 Sodium/hydrogen exchanger family 25 425 2.9E-48 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 THSYN_RS02985 266e891ab0dc48ba2808a00d3779d3bb 443 Gene3D G3DSA:1.20.91.10 273 360 6.5E-20 T 29-03-2018 THSYN_RS00655 d651a7d739d6e47625de05653f60d155 307 Gene3D G3DSA:3.10.450.50 99 307 7.4E-16 T 29-03-2018 THSYN_RS00655 d651a7d739d6e47625de05653f60d155 307 SUPERFAMILY SSF103642 286 306 1.46E-7 T 29-03-2018 THSYN_RS00655 d651a7d739d6e47625de05653f60d155 307 Pfam PF02810 SEC-C motif 289 306 6.0E-10 T 29-03-2018 IPR004027 SEC-C motif THSYN_RS00655 d651a7d739d6e47625de05653f60d155 307 Pfam PF06685 Protein of unknown function (DUF1186) 4 257 2.7E-44 T 29-03-2018 IPR010602 Protein of unknown function DUF1186 THSYN_RS06180 e145d59def0378898f495ee6e6810d75 86 Gene3D G3DSA:1.10.1220.10 1 45 4.9E-7 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS06180 e145d59def0378898f495ee6e6810d75 86 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 36 5.2E-7 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 PIRSF PIRSF000729 7 374 2.2E-127 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 SMART SM00359 283 370 1.1E-13 T 29-03-2018 IPR002478 PUA domain GO:0003723 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 ProSitePatterns PS00902 Glutamate 5-kinase signature. 213 230 - T 29-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 Pfam PF01472 PUA domain 283 356 1.3E-17 T 29-03-2018 IPR002478 PUA domain GO:0003723 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 PRINTS PR00474 Glutamate 5-kinase family signature 154 181 2.2E-53 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 PRINTS PR00474 Glutamate 5-kinase family signature 48 62 2.2E-53 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 PRINTS PR00474 Glutamate 5-kinase family signature 122 143 2.2E-53 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 PRINTS PR00474 Glutamate 5-kinase family signature 82 110 2.2E-53 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 PRINTS PR00474 Glutamate 5-kinase family signature 215 235 2.2E-53 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 Gene3D G3DSA:3.40.1160.10 1 271 1.4E-64 T 29-03-2018 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 SUPERFAMILY SSF88697 282 373 2.6E-23 T 29-03-2018 IPR015947 PUA-like domain THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 TIGRFAM TIGR01027 proB: glutamate 5-kinase 12 372 6.8E-128 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 Hamap MF_00456 Glutamate 5-kinase [proB]. 11 265 36.257 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 Pfam PF00696 Amino acid kinase family 12 239 4.7E-43 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 Gene3D G3DSA:2.30.130.10 281 373 7.5E-29 T 29-03-2018 IPR002478 PUA domain GO:0003723 THSYN_RS24475 391c79f6235262f724149cd495ede5c1 374 SUPERFAMILY SSF53633 11 263 4.32E-68 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase THSYN_RS10985 2f67db3aeefaafad292e08b99797d912 505 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 465 1.8E-152 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 THSYN_RS10985 2f67db3aeefaafad292e08b99797d912 505 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 465 44.2 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 THSYN_RS10985 2f67db3aeefaafad292e08b99797d912 505 PIRSF PIRSF000485 1 482 1.2E-154 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 THSYN_RS10985 2f67db3aeefaafad292e08b99797d912 505 Gene3D G3DSA:3.60.20.10 2 256 2.9E-50 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS10985 2f67db3aeefaafad292e08b99797d912 505 Pfam PF00156 Phosphoribosyl transferase domain 268 393 1.3E-8 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THSYN_RS10985 2f67db3aeefaafad292e08b99797d912 505 Gene3D G3DSA:3.40.50.2020 275 444 3.7E-35 T 29-03-2018 THSYN_RS10985 2f67db3aeefaafad292e08b99797d912 505 SUPERFAMILY SSF56235 2 257 9.44E-70 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS10985 2f67db3aeefaafad292e08b99797d912 505 SUPERFAMILY SSF53271 250 484 6.59E-72 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like THSYN_RS10985 2f67db3aeefaafad292e08b99797d912 505 Pfam PF13522 Glutamine amidotransferase domain 64 208 8.1E-17 T 29-03-2018 THSYN_RS12580 c51ea0922d04e97040d18f7a6478f15a 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS12580 c51ea0922d04e97040d18f7a6478f15a 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS12580 c51ea0922d04e97040d18f7a6478f15a 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS12580 c51ea0922d04e97040d18f7a6478f15a 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS12580 c51ea0922d04e97040d18f7a6478f15a 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS12580 c51ea0922d04e97040d18f7a6478f15a 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS12580 c51ea0922d04e97040d18f7a6478f15a 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS12580 c51ea0922d04e97040d18f7a6478f15a 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 1.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS12580 c51ea0922d04e97040d18f7a6478f15a 240 SUPERFAMILY SSF51735 4 239 2.17E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS12580 c51ea0922d04e97040d18f7a6478f15a 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 238 5.0E-41 T 29-03-2018 THSYN_RS12580 c51ea0922d04e97040d18f7a6478f15a 240 Gene3D G3DSA:3.40.50.720 2 240 2.0E-50 T 29-03-2018 THSYN_RS18420 1fc775fdd25ae057f8503063b15e4084 665 Gene3D G3DSA:3.40.50.150 185 566 1.3E-39 T 29-03-2018 THSYN_RS18420 1fc775fdd25ae057f8503063b15e4084 665 Pfam PF12161 HsdM N-terminal domain 13 134 7.7E-12 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS18420 1fc775fdd25ae057f8503063b15e4084 665 Pfam PF02384 N-6 DNA Methylase 167 477 1.4E-52 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS18420 1fc775fdd25ae057f8503063b15e4084 665 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 187 203 2.1E-10 T 29-03-2018 THSYN_RS18420 1fc775fdd25ae057f8503063b15e4084 665 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 214 228 2.1E-10 T 29-03-2018 THSYN_RS18420 1fc775fdd25ae057f8503063b15e4084 665 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 305 317 2.1E-10 T 29-03-2018 THSYN_RS18420 1fc775fdd25ae057f8503063b15e4084 665 SUPERFAMILY SSF53335 12 50 2.87E-95 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS18420 1fc775fdd25ae057f8503063b15e4084 665 SUPERFAMILY SSF53335 78 501 2.87E-95 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS18420 1fc775fdd25ae057f8503063b15e4084 665 SUPERFAMILY SSF53335 622 662 2.87E-95 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS19070 8c2932aa8034ff325ee46aa58918f51e 590 SUPERFAMILY SSF90123 16 331 3.01E-54 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS19070 8c2932aa8034ff325ee46aa58918f51e 590 Gene3D G3DSA:1.20.1560.10 3 336 6.1E-43 T 29-03-2018 THSYN_RS19070 8c2932aa8034ff325ee46aa58918f51e 590 Pfam PF00664 ABC transporter transmembrane region 19 266 2.1E-34 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS19070 8c2932aa8034ff325ee46aa58918f51e 590 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 17 558 2.0E-192 T 29-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 THSYN_RS19070 8c2932aa8034ff325ee46aa58918f51e 590 SUPERFAMILY SSF52540 347 584 6.04E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19070 8c2932aa8034ff325ee46aa58918f51e 590 Gene3D G3DSA:3.40.50.300 343 589 5.9E-71 T 29-03-2018 THSYN_RS19070 8c2932aa8034ff325ee46aa58918f51e 590 SMART SM00382 376 562 3.6E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS19070 8c2932aa8034ff325ee46aa58918f51e 590 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS19070 8c2932aa8034ff325ee46aa58918f51e 590 Pfam PF00005 ABC transporter 369 516 8.5E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS16185 e13625da52b75bc2dd677fee126a5d1a 412 SMART SM00825 Beta-ketoacyl synthase 6 412 1.6E-17 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain THSYN_RS16185 e13625da52b75bc2dd677fee126a5d1a 412 SUPERFAMILY SSF53901 4 252 4.88E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS16185 e13625da52b75bc2dd677fee126a5d1a 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 410 3.2E-195 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 THSYN_RS16185 e13625da52b75bc2dd677fee126a5d1a 412 Gene3D G3DSA:3.40.47.10 263 412 9.7E-54 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS16185 e13625da52b75bc2dd677fee126a5d1a 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 369 8.2E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal THSYN_RS16185 e13625da52b75bc2dd677fee126a5d1a 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site THSYN_RS16185 e13625da52b75bc2dd677fee126a5d1a 412 SUPERFAMILY SSF53901 215 411 4.97E-75 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS16185 e13625da52b75bc2dd677fee126a5d1a 412 PIRSF PIRSF000447 1 412 2.0E-186 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 THSYN_RS16185 e13625da52b75bc2dd677fee126a5d1a 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 247 3.3E-60 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal THSYN_RS16185 e13625da52b75bc2dd677fee126a5d1a 412 Gene3D G3DSA:3.40.47.10 6 260 2.4E-80 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS31335 f92c0bcabe6a5b078825b2a18d7001e5 463 Gene3D G3DSA:1.20.1250.20 235 452 7.4E-12 T 29-03-2018 THSYN_RS31335 f92c0bcabe6a5b078825b2a18d7001e5 463 SUPERFAMILY SSF103473 24 448 6.67E-25 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS31335 f92c0bcabe6a5b078825b2a18d7001e5 463 Gene3D G3DSA:1.20.1250.20 22 228 4.7E-10 T 29-03-2018 THSYN_RS31335 f92c0bcabe6a5b078825b2a18d7001e5 463 Pfam PF03209 PUCC protein 46 445 1.4E-119 T 29-03-2018 IPR004896 PucC-related THSYN_RS31335 f92c0bcabe6a5b078825b2a18d7001e5 463 PIRSF PIRSF016565 10 456 1.4E-113 T 29-03-2018 IPR026036 PucC protein THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 SUPERFAMILY SSF52922 489 615 1.44E-31 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 9 616 2.6E-263 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 Gene3D G3DSA:3.40.50.970 295 483 8.1E-63 T 29-03-2018 THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 Pfam PF02780 Transketolase, C-terminal domain 492 608 2.2E-26 T 29-03-2018 IPR033248 Transketolase, C-terminal domain THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 SUPERFAMILY SSF52518 3 196 9.98E-83 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 SUPERFAMILY SSF52518 240 378 9.98E-83 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 7 617 45.766 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 SMART SM00861 316 480 1.4E-67 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 8 279 1.0E-122 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 Pfam PF02779 Transketolase, pyrimidine binding domain 316 477 9.6E-37 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 Gene3D G3DSA:3.40.50.970 1 294 1.8E-83 T 29-03-2018 THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 ProSitePatterns PS00801 Transketolase signature 1. 33 52 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 Gene3D G3DSA:3.40.50.920 492 618 4.2E-34 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS31280 45b95b86cc3b440df2ace52f51f7a1b0 633 SUPERFAMILY SSF52518 314 501 6.48E-59 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS30180 486bb44c32baad470ca1e57f93762c18 170 Pfam PF00271 Helicase conserved C-terminal domain 20 90 4.7E-6 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS30180 486bb44c32baad470ca1e57f93762c18 170 SUPERFAMILY SSF52540 24 147 1.67E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30180 486bb44c32baad470ca1e57f93762c18 170 Gene3D G3DSA:3.40.50.300 17 130 2.4E-12 T 29-03-2018 THSYN_RS30180 486bb44c32baad470ca1e57f93762c18 170 SMART SM00490 6 92 0.0081 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS24330 a5fe634ba282b6bb9653915511e033b3 346 Pfam PF04932 O-Antigen ligase 129 270 1.9E-8 T 29-03-2018 IPR007016 O-antigen ligase-related THSYN_RS00445 b0403b87b485f9edf8c019dd1cb31a4f 129 TIGRFAM TIGR03166 alt_F1F0_F1_eps: alternate F1F0 ATPase, F1 subunit epsilon 2 123 3.8E-47 T 29-03-2018 IPR024037 Alternate ATP synthase, F1 complex, subunit epsilon THSYN_RS00445 b0403b87b485f9edf8c019dd1cb31a4f 129 SUPERFAMILY SSF51344 1 82 1.7E-15 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00445 b0403b87b485f9edf8c019dd1cb31a4f 129 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 8 58 0.001 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00445 b0403b87b485f9edf8c019dd1cb31a4f 129 Gene3D G3DSA:2.60.15.10 1 87 6.0E-12 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00445 b0403b87b485f9edf8c019dd1cb31a4f 129 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 1 81 6.8E-15 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS13635 96bfcad0204293e9ede148d0c027903b 173 Pfam PF14341 PilX N-terminal 16 66 8.2E-10 T 29-03-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain THSYN_RS13635 96bfcad0204293e9ede148d0c027903b 173 Pfam PF13681 Type IV pilus assembly protein PilX C-term 100 173 4.5E-12 T 29-03-2018 IPR025205 PilX/PilW C-terminal domain THSYN_RS31710 c0352a8a95a739a821a5813233a93a95 241 Pfam PF05685 Putative restriction endonuclease 42 150 3.2E-16 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS31710 c0352a8a95a739a821a5813233a93a95 241 Gene3D G3DSA:3.90.1570.10 19 162 1.3E-21 T 29-03-2018 THSYN_RS31710 c0352a8a95a739a821a5813233a93a95 241 SUPERFAMILY SSF52980 6 165 1.34E-30 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS02895 8e205bbe42878d83fb3b742a5420a803 84 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 19 54 6.4E-8 T 29-03-2018 THSYN_RS02895 8e205bbe42878d83fb3b742a5420a803 84 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 62 6.6E-10 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS02895 8e205bbe42878d83fb3b742a5420a803 84 Gene3D G3DSA:3.40.1620.10 3 50 2.1E-10 T 29-03-2018 THSYN_RS02895 8e205bbe42878d83fb3b742a5420a803 84 SUPERFAMILY SSF143120 4 72 1.57E-11 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS10385 18d5c339a0b6ed9189e90262659b8ef0 128 Pfam PF05168 HEPN domain 8 122 3.4E-9 T 29-03-2018 IPR007842 HEPN domain THSYN_RS10385 18d5c339a0b6ed9189e90262659b8ef0 128 Gene3D G3DSA:1.20.120.330 2 127 2.1E-15 T 29-03-2018 THSYN_RS11785 7bf11b1a7dc9ef00230595904dac6e22 250 Gene3D G3DSA:3.40.1390.30 110 221 1.5E-28 T 29-03-2018 THSYN_RS11785 7bf11b1a7dc9ef00230595904dac6e22 250 Gene3D G3DSA:3.40.1390.30 5 109 5.4E-22 T 29-03-2018 THSYN_RS11785 7bf11b1a7dc9ef00230595904dac6e22 250 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 238 2.2E-49 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 THSYN_RS11785 7bf11b1a7dc9ef00230595904dac6e22 250 SUPERFAMILY SSF102705 6 249 2.22E-70 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 THSYN_RS11785 7bf11b1a7dc9ef00230595904dac6e22 250 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 9 249 1.8E-52 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 THSYN_RS30710 f835ddd8b2c1f7cb1112e5db13793bfa 571 Gene3D G3DSA:3.30.420.10 194 351 0.0016 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS18395 f835ddd8b2c1f7cb1112e5db13793bfa 571 Gene3D G3DSA:3.30.420.10 194 351 0.0016 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS15850 f835ddd8b2c1f7cb1112e5db13793bfa 571 Gene3D G3DSA:3.30.420.10 194 351 0.0016 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS16765 f835ddd8b2c1f7cb1112e5db13793bfa 571 Gene3D G3DSA:3.30.420.10 194 351 0.0016 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS19415 f835ddd8b2c1f7cb1112e5db13793bfa 571 Gene3D G3DSA:3.30.420.10 194 351 0.0016 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS01805 efd9694421a922fdfbcb3c6f3e636e7d 63 Gene3D G3DSA:3.30.2390.10 4 54 7.7E-9 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS01805 efd9694421a922fdfbcb3c6f3e636e7d 63 SUPERFAMILY SSF143100 3 46 1.16E-9 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS18945 57c4da18e5167754bceb402493a2c27b 184 Gene3D G3DSA:3.90.70.10 42 184 2.2E-19 T 29-03-2018 THSYN_RS18945 57c4da18e5167754bceb402493a2c27b 184 Pfam PF03412 Peptidase C39 family 43 180 7.1E-15 T 29-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 THSYN_RS08805 f3219702ff58b694e08f159d1693d9dd 162 SUPERFAMILY SSF52833 89 156 5.23E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS08805 f3219702ff58b694e08f159d1693d9dd 162 Gene3D G3DSA:3.40.30.10 101 160 9.3E-16 T 29-03-2018 THSYN_RS08805 f3219702ff58b694e08f159d1693d9dd 162 Pfam PF00462 Glutaredoxin 90 144 6.3E-12 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 THSYN_RS08805 f3219702ff58b694e08f159d1693d9dd 162 Pfam PF13511 Domain of unknown function (DUF4124) 19 70 4.5E-12 T 29-03-2018 IPR025392 Domain of unknown function DUF4124 THSYN_RS08805 f3219702ff58b694e08f159d1693d9dd 162 Gene3D G3DSA:3.40.30.10 69 100 0.0079 T 29-03-2018 THSYN_RS07265 4f77ac3e6abfc2483891c5d2066850d9 282 Gene3D G3DSA:3.90.1570.10 23 213 2.0E-20 T 29-03-2018 THSYN_RS07265 4f77ac3e6abfc2483891c5d2066850d9 282 Pfam PF05685 Putative restriction endonuclease 37 206 1.9E-14 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS07265 4f77ac3e6abfc2483891c5d2066850d9 282 SUPERFAMILY SSF52980 26 210 7.51E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS20440 8aa49e0aa344fd19f1c269afd761e840 1130 Gene3D G3DSA:3.40.50.150 2 369 2.4E-28 T 29-03-2018 THSYN_RS20440 8aa49e0aa344fd19f1c269afd761e840 1130 SUPERFAMILY SSF53335 225 392 1.48E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS20440 8aa49e0aa344fd19f1c269afd761e840 1130 SUPERFAMILY SSF53335 4 88 1.48E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS20440 8aa49e0aa344fd19f1c269afd761e840 1130 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 233 239 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS20440 8aa49e0aa344fd19f1c269afd761e840 1130 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 11 25 3.3E-6 T 29-03-2018 THSYN_RS20440 8aa49e0aa344fd19f1c269afd761e840 1130 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 230 242 3.3E-6 T 29-03-2018 THSYN_RS20440 8aa49e0aa344fd19f1c269afd761e840 1130 Pfam PF07669 Eco57I restriction-modification methylase 228 317 9.1E-6 T 29-03-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 THSYN_RS20440 8aa49e0aa344fd19f1c269afd761e840 1130 Gene3D G3DSA:3.90.220.10 389 582 7.9E-21 T 29-03-2018 THSYN_RS18480 c6d4ce471c7445c4bf83b79f69fe8f6c 169 Pfam PF01899 Na+/H+ ion antiporter subunit 11 148 5.3E-22 T 29-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 THSYN_RS22210 e8177827eeb1dd849c7b9d38fa9de957 459 Gene3D G3DSA:3.40.640.10 79 340 3.1E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS22210 e8177827eeb1dd849c7b9d38fa9de957 459 SUPERFAMILY SSF53383 1 451 9.63E-111 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS22210 e8177827eeb1dd849c7b9d38fa9de957 459 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 1 451 45.551 T 29-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 THSYN_RS22210 e8177827eeb1dd849c7b9d38fa9de957 459 Pfam PF02347 Glycine cleavage system P-protein 3 442 3.7E-114 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 THSYN_RS22210 e8177827eeb1dd849c7b9d38fa9de957 459 PIRSF PIRSF006815 1 452 1.4E-160 T 29-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 THSYN_RS22210 e8177827eeb1dd849c7b9d38fa9de957 459 Gene3D G3DSA:3.90.1150.10 341 453 4.2E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS02945 be637e3b8c52d346c8a15b7d68d948d5 317 SUPERFAMILY SSF52218 5 156 3.71E-11 T 29-03-2018 IPR029039 Flavoprotein-like domain THSYN_RS02945 be637e3b8c52d346c8a15b7d68d948d5 317 Gene3D G3DSA:3.40.50.360 2 214 2.1E-16 T 29-03-2018 IPR029039 Flavoprotein-like domain THSYN_RS22485 d4195a111cfa951431b3301d1da6002b 700 SUPERFAMILY SSF53955 49 270 9.56E-57 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS22485 d4195a111cfa951431b3301d1da6002b 700 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 613 697 2.9E-20 T 29-03-2018 IPR009647 Penicillin-binding, C-terminal THSYN_RS22485 d4195a111cfa951431b3301d1da6002b 700 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 49 586 1.4E-189 T 29-03-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 THSYN_RS22485 d4195a111cfa951431b3301d1da6002b 700 Pfam PF00912 Transglycosylase 75 237 9.6E-41 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 THSYN_RS22485 d4195a111cfa951431b3301d1da6002b 700 Pfam PF00905 Penicillin binding protein transpeptidase domain 315 537 2.2E-14 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THSYN_RS22485 d4195a111cfa951431b3301d1da6002b 700 Gene3D G3DSA:1.10.3810.10 53 255 2.5E-47 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 THSYN_RS22485 d4195a111cfa951431b3301d1da6002b 700 Gene3D G3DSA:3.40.710.10 280 603 4.3E-59 T 29-03-2018 THSYN_RS22485 d4195a111cfa951431b3301d1da6002b 700 SUPERFAMILY SSF56601 269 587 2.82E-81 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS22485 d4195a111cfa951431b3301d1da6002b 700 SUPERFAMILY SSF56601 220 242 2.82E-81 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS13850 86763eb8ede325e11a1d89f43dad39ac 407 Pfam PF13519 von Willebrand factor type A domain 59 171 1.9E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS13850 86763eb8ede325e11a1d89f43dad39ac 407 SMART SM00327 55 238 1.5E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS13850 86763eb8ede325e11a1d89f43dad39ac 407 Gene3D G3DSA:3.40.50.410 54 225 8.8E-26 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS13850 86763eb8ede325e11a1d89f43dad39ac 407 SUPERFAMILY SSF53300 56 227 3.81E-25 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS17140 95ced07b46ec24058d1ca53ed6b9db8c 423 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 290 363 5.8E-20 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS17140 95ced07b46ec24058d1ca53ed6b9db8c 423 PIRSF PIRSF029347 1 161 3.9E-10 T 29-03-2018 IPR014555 RecF-like THSYN_RS17140 95ced07b46ec24058d1ca53ed6b9db8c 423 PIRSF PIRSF029347 208 399 1.5E-10 T 29-03-2018 IPR014555 RecF-like THSYN_RS17140 95ced07b46ec24058d1ca53ed6b9db8c 423 SUPERFAMILY SSF52540 183 368 1.53E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17140 95ced07b46ec24058d1ca53ed6b9db8c 423 SUPERFAMILY SSF52540 1 116 1.53E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17140 95ced07b46ec24058d1ca53ed6b9db8c 423 Gene3D G3DSA:3.40.50.300 1 370 1.8E-24 T 29-03-2018 THSYN_RS17140 95ced07b46ec24058d1ca53ed6b9db8c 423 Pfam PF13175 AAA ATPase domain 1 45 2.3E-9 T 29-03-2018 THSYN_RS06555 6b7386a3a0efc9493616c0de8d5fbe58 683 Gene3D G3DSA:3.40.720.10 243 594 4.4E-13 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS06555 6b7386a3a0efc9493616c0de8d5fbe58 683 Pfam PF04185 Phosphoesterase family 170 591 2.7E-51 T 29-03-2018 IPR007312 Phosphoesterase GO:0016788 THSYN_RS21570 e8026bf10c56f63faa7015c52fc7c736 492 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 37 441 1.7E-106 T 29-03-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 THSYN_RS21570 e8026bf10c56f63faa7015c52fc7c736 492 SUPERFAMILY SSF53807 4 454 2.49E-133 T 29-03-2018 THSYN_RS21570 e8026bf10c56f63faa7015c52fc7c736 492 Gene3D G3DSA:3.40.50.1980 24 177 1.2E-50 T 29-03-2018 THSYN_RS21570 e8026bf10c56f63faa7015c52fc7c736 492 Gene3D G3DSA:3.40.50.1980 287 367 2.5E-24 T 29-03-2018 THSYN_RS21570 e8026bf10c56f63faa7015c52fc7c736 492 Gene3D G3DSA:3.40.50.1980 368 456 8.8E-19 T 29-03-2018 THSYN_RS21570 e8026bf10c56f63faa7015c52fc7c736 492 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 122 136 - T 29-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 THSYN_RS21570 e8026bf10c56f63faa7015c52fc7c736 492 Gene3D G3DSA:3.40.50.1980 194 286 3.7E-24 T 29-03-2018 THSYN_RS21570 e8026bf10c56f63faa7015c52fc7c736 492 TIGRFAM TIGR01283 nifE: nitrogenase MoFe cofactor biosynthesis protein NifE 3 456 2.3E-211 T 29-03-2018 IPR005973 Nitrogenase MoFe cofactor biosynthesis protein NifE GO:0006461|GO:0009399 THSYN_RS21570 e8026bf10c56f63faa7015c52fc7c736 492 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 55 62 - T 29-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 THSYN_RS18740 66db4a108f0efbffe3f087d5c3b3395d 353 SUPERFAMILY SSF46689 274 322 1.52E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS18740 66db4a108f0efbffe3f087d5c3b3395d 353 Pfam PF12833 Helix-turn-helix domain 245 322 9.8E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THSYN_RS18740 66db4a108f0efbffe3f087d5c3b3395d 353 SMART SM00342 239 323 7.5E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THSYN_RS18740 66db4a108f0efbffe3f087d5c3b3395d 353 Pfam PF14525 AraC-binding-like domain 34 203 2.3E-17 T 29-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like THSYN_RS18740 66db4a108f0efbffe3f087d5c3b3395d 353 Gene3D G3DSA:1.10.10.60 273 330 8.0E-11 T 29-03-2018 THSYN_RS18740 66db4a108f0efbffe3f087d5c3b3395d 353 Gene3D G3DSA:1.10.10.60 225 272 4.6E-4 T 29-03-2018 THSYN_RS18145 ff767b93f5856fb94d6ba6a541fdfd6d 344 Pfam PF12710 haloacid dehalogenase-like hydrolase 68 276 3.1E-15 T 29-03-2018 THSYN_RS18145 ff767b93f5856fb94d6ba6a541fdfd6d 344 SUPERFAMILY SSF56784 64 281 2.98E-14 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS18145 ff767b93f5856fb94d6ba6a541fdfd6d 344 Gene3D G3DSA:3.40.50.1000 64 342 1.7E-15 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS16760 dc33d21209ab2964b7d86604e6c66c3a 179 SUPERFAMILY SSF52540 10 138 2.07E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16760 dc33d21209ab2964b7d86604e6c66c3a 179 Pfam PF01695 IstB-like ATP binding protein 2 140 2.4E-43 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 THSYN_RS16760 dc33d21209ab2964b7d86604e6c66c3a 179 Gene3D G3DSA:3.40.50.300 3 164 4.4E-15 T 29-03-2018 THSYN_RS16760 dc33d21209ab2964b7d86604e6c66c3a 179 SMART SM00382 8 141 1.4E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS10535 252cb497f416417f1bcb708636e6fced 467 Pfam PF08328 Adenylosuccinate lyase C-terminal 337 451 9.4E-49 T 29-03-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 THSYN_RS10535 252cb497f416417f1bcb708636e6fced 467 ProSitePatterns PS00163 Fumarate lyases signature. 300 309 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 THSYN_RS10535 252cb497f416417f1bcb708636e6fced 467 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 18 458 2.3E-126 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THSYN_RS10535 252cb497f416417f1bcb708636e6fced 467 Gene3D G3DSA:1.10.40.30 397 451 2.0E-29 T 29-03-2018 THSYN_RS10535 252cb497f416417f1bcb708636e6fced 467 Gene3D G3DSA:1.10.275.10 7 123 3.2E-43 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal THSYN_RS10535 252cb497f416417f1bcb708636e6fced 467 SUPERFAMILY SSF48557 16 458 4.24E-105 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 THSYN_RS10535 252cb497f416417f1bcb708636e6fced 467 Gene3D G3DSA:1.20.200.10 124 396 1.4E-84 T 29-03-2018 THSYN_RS10535 252cb497f416417f1bcb708636e6fced 467 PRINTS PR00149 Fumarate lyase superfamily signature 300 316 9.0E-16 T 29-03-2018 IPR000362 Fumarate lyase family THSYN_RS10535 252cb497f416417f1bcb708636e6fced 467 PRINTS PR00149 Fumarate lyase superfamily signature 169 187 9.0E-16 T 29-03-2018 IPR000362 Fumarate lyase family THSYN_RS10535 252cb497f416417f1bcb708636e6fced 467 PRINTS PR00149 Fumarate lyase superfamily signature 123 141 9.0E-16 T 29-03-2018 IPR000362 Fumarate lyase family THSYN_RS10535 252cb497f416417f1bcb708636e6fced 467 PRINTS PR00149 Fumarate lyase superfamily signature 257 284 9.0E-16 T 29-03-2018 IPR000362 Fumarate lyase family THSYN_RS10535 252cb497f416417f1bcb708636e6fced 467 Pfam PF00206 Lyase 20 318 1.2E-60 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal THSYN_RS05000 77544679ae9bf451172cb5f5c1190ce2 85 Gene3D G3DSA:3.30.110.40 1 68 1.3E-4 T 29-03-2018 IPR001455 TusA-like domain THSYN_RS05000 77544679ae9bf451172cb5f5c1190ce2 85 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 4 68 3.6E-17 T 29-03-2018 IPR018720 Domain of unknown function DUF2249 THSYN_RS05000 77544679ae9bf451172cb5f5c1190ce2 85 SUPERFAMILY SSF64307 3 67 1.28E-9 T 29-03-2018 IPR001455 TusA-like domain THSYN_RS17185 5de9124f03d3d78522520e1c37e9ed94 162 SMART SM00748 40 147 1.5E-9 T 29-03-2018 IPR007842 HEPN domain THSYN_RS17185 5de9124f03d3d78522520e1c37e9ed94 162 Pfam PF05168 HEPN domain 37 150 2.8E-23 T 29-03-2018 IPR007842 HEPN domain THSYN_RS17185 5de9124f03d3d78522520e1c37e9ed94 162 Gene3D G3DSA:1.20.120.330 32 157 3.7E-22 T 29-03-2018 THSYN_RS17185 5de9124f03d3d78522520e1c37e9ed94 162 SUPERFAMILY SSF81593 39 150 2.04E-18 T 29-03-2018 THSYN_RS21860 9099063487c650f2a86ad79f09f0cfba 568 Pfam PF01609 Transposase DDE domain 189 463 2.6E-15 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS21860 9099063487c650f2a86ad79f09f0cfba 568 Gene3D G3DSA:3.90.350.10 147 446 9.5E-36 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS21860 9099063487c650f2a86ad79f09f0cfba 568 SUPERFAMILY SSF53098 399 470 6.37E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS30450 a4f000c3ed45b08e93af299fc47e4194 89 Gene3D G3DSA:3.40.1620.10 8 65 9.2E-12 T 29-03-2018 THSYN_RS30450 a4f000c3ed45b08e93af299fc47e4194 89 SUPERFAMILY SSF143120 8 79 1.07E-12 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS30450 a4f000c3ed45b08e93af299fc47e4194 89 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 60 8.5E-13 T 29-03-2018 THSYN_RS30450 a4f000c3ed45b08e93af299fc47e4194 89 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 7 78 1.8E-13 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS18405 0cd3a6c94cec6e50b22efd0e46d32603 221 Gene3D G3DSA:1.10.287.1120 170 220 1.4E-6 T 29-03-2018 THSYN_RS18405 0cd3a6c94cec6e50b22efd0e46d32603 221 Pfam PF01420 Type I restriction modification DNA specificity domain 5 173 6.5E-6 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS18405 0cd3a6c94cec6e50b22efd0e46d32603 221 SUPERFAMILY SSF116734 3 211 9.48E-34 T 29-03-2018 THSYN_RS18405 0cd3a6c94cec6e50b22efd0e46d32603 221 Gene3D G3DSA:3.90.220.20 1 169 1.4E-24 T 29-03-2018 THSYN_RS23150 30cd14e0078fa876e36c389cfb29632c 338 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 153 2.3E-40 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 THSYN_RS23150 30cd14e0078fa876e36c389cfb29632c 338 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 337 3.1E-121 T 29-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 THSYN_RS23150 30cd14e0078fa876e36c389cfb29632c 338 SUPERFAMILY SSF51735 1 156 2.31E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS23150 30cd14e0078fa876e36c389cfb29632c 338 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 184 214 3.0E-9 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THSYN_RS23150 30cd14e0078fa876e36c389cfb29632c 338 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 23 1.6E-16 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THSYN_RS23150 30cd14e0078fa876e36c389cfb29632c 338 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 58 87 1.6E-16 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THSYN_RS23150 30cd14e0078fa876e36c389cfb29632c 338 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 111 136 1.6E-16 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THSYN_RS23150 30cd14e0078fa876e36c389cfb29632c 338 Gene3D G3DSA:3.40.50.720 1 185 4.0E-36 T 29-03-2018 THSYN_RS23150 30cd14e0078fa876e36c389cfb29632c 338 SUPERFAMILY SSF48179 182 332 4.01E-36 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THSYN_RS23150 30cd14e0078fa876e36c389cfb29632c 338 Gene3D G3DSA:1.10.1040.10 186 338 4.4E-40 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THSYN_RS23150 30cd14e0078fa876e36c389cfb29632c 338 SMART SM01350 184 334 4.1E-5 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THSYN_RS23150 30cd14e0078fa876e36c389cfb29632c 338 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 THSYN_RS21335 c67bd6a6f7c6df4e5f11b5b0c16d246b 332 Pfam PF13480 Acetyltransferase (GNAT) domain 162 295 4.1E-17 T 29-03-2018 THSYN_RS21335 c67bd6a6f7c6df4e5f11b5b0c16d246b 332 SUPERFAMILY SSF55729 152 303 1.34E-31 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS21335 c67bd6a6f7c6df4e5f11b5b0c16d246b 332 Gene3D G3DSA:3.40.630.30 14 161 1.6E-23 T 29-03-2018 THSYN_RS21335 c67bd6a6f7c6df4e5f11b5b0c16d246b 332 TIGRFAM TIGR03019 pepcterm_femAB: FemAB-related protein, PEP-CTERM system-associated 26 308 1.0E-118 T 29-03-2018 IPR017469 PEP-CTERM system-associated, FemAB-related THSYN_RS21335 c67bd6a6f7c6df4e5f11b5b0c16d246b 332 Gene3D G3DSA:3.40.630.30 162 300 2.8E-22 T 29-03-2018 THSYN_RS21335 c67bd6a6f7c6df4e5f11b5b0c16d246b 332 SUPERFAMILY SSF55729 20 126 9.32E-6 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS06265 006289a31e0d6a3636a588fd24e087ee 723 SUPERFAMILY SSF53474 45 369 2.13E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS06265 006289a31e0d6a3636a588fd24e087ee 723 Gene3D G3DSA:3.40.50.1820 5 383 2.1E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS06265 006289a31e0d6a3636a588fd24e087ee 723 Pfam PF11339 Protein of unknown function (DUF3141) 14 593 2.8E-279 T 29-03-2018 IPR024501 Protein of unknown function DUF3141 THSYN_RS23805 41450d2ac618c276063a2b33bd6ea3bb 118 Gene3D G3DSA:4.10.910.10 67 84 4.9E-17 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23805 41450d2ac618c276063a2b33bd6ea3bb 118 Gene3D G3DSA:1.10.8.50 1 66 3.9E-22 T 29-03-2018 THSYN_RS23805 41450d2ac618c276063a2b33bd6ea3bb 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 25.232 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23805 41450d2ac618c276063a2b33bd6ea3bb 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.2E-50 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23805 41450d2ac618c276063a2b33bd6ea3bb 118 Gene3D G3DSA:4.10.910.10 85 118 3.4E-23 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23805 41450d2ac618c276063a2b33bd6ea3bb 118 PIRSF PIRSF002134 1 118 1.0E-38 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23805 41450d2ac618c276063a2b33bd6ea3bb 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23805 41450d2ac618c276063a2b33bd6ea3bb 118 SUPERFAMILY SSF46946 2 114 6.67E-44 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 THSYN_RS23805 41450d2ac618c276063a2b33bd6ea3bb 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.1E-29 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS10970 d23d12c467438b123af9cb099f1c5b6f 426 SUPERFAMILY SSF53623 7 288 1.7E-80 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS10970 d23d12c467438b123af9cb099f1c5b6f 426 TIGRFAM TIGR01499 folC: bifunctional protein FolC 28 422 7.7E-90 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 THSYN_RS10970 d23d12c467438b123af9cb099f1c5b6f 426 Gene3D G3DSA:3.40.1190.10 3 290 1.6E-74 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS10970 d23d12c467438b123af9cb099f1c5b6f 426 Gene3D G3DSA:3.90.190.20 292 425 9.1E-29 T 29-03-2018 THSYN_RS10970 d23d12c467438b123af9cb099f1c5b6f 426 SUPERFAMILY SSF53244 292 425 1.07E-25 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THSYN_RS10970 d23d12c467438b123af9cb099f1c5b6f 426 PIRSF PIRSF001563 2 425 2.9E-101 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 THSYN_RS10970 d23d12c467438b123af9cb099f1c5b6f 426 Pfam PF08245 Mur ligase middle domain 50 266 3.4E-9 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS29015 5990af99c5ddeb193ec209c14e11691a 360 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 330 1.4E-69 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 THSYN_RS29015 5990af99c5ddeb193ec209c14e11691a 360 SUPERFAMILY SSF53756 1 329 4.46E-88 T 29-03-2018 THSYN_RS29015 5990af99c5ddeb193ec209c14e11691a 360 Gene3D G3DSA:3.40.50.2000 202 335 2.8E-19 T 29-03-2018 THSYN_RS29015 5990af99c5ddeb193ec209c14e11691a 360 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 27 329 4.8E-82 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 THSYN_RS29015 5990af99c5ddeb193ec209c14e11691a 360 Gene3D G3DSA:3.40.50.2000 1 201 3.7E-58 T 29-03-2018 THSYN_RS00875 fc4fa35ea637e1c055580e9840efd85c 538 Pfam PF02540 NAD synthase 267 515 1.4E-74 T 29-03-2018 IPR022310 NAD/GMP synthase THSYN_RS00875 fc4fa35ea637e1c055580e9840efd85c 538 Gene3D G3DSA:3.40.50.620 264 538 5.3E-69 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS00875 fc4fa35ea637e1c055580e9840efd85c 538 Pfam PF00795 Carbon-nitrogen hydrolase 7 241 1.9E-30 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THSYN_RS00875 fc4fa35ea637e1c055580e9840efd85c 538 SUPERFAMILY SSF56317 4 242 4.19E-64 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THSYN_RS00875 fc4fa35ea637e1c055580e9840efd85c 538 SUPERFAMILY SSF52402 260 523 1.16E-80 T 29-03-2018 THSYN_RS00875 fc4fa35ea637e1c055580e9840efd85c 538 TIGRFAM TIGR00552 nadE: NAD+ synthetase 274 517 4.3E-62 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 THSYN_RS00875 fc4fa35ea637e1c055580e9840efd85c 538 PIRSF PIRSF006630 2 538 7.9E-198 T 29-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 THSYN_RS00875 fc4fa35ea637e1c055580e9840efd85c 538 Gene3D G3DSA:3.60.110.10 2 244 9.6E-64 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THSYN_RS00875 fc4fa35ea637e1c055580e9840efd85c 538 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 35 50 - T 29-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 THSYN_RS07010 1ce3c7ba7fc88f2d3a6938e6fb61251e 356 Pfam PF00892 EamA-like transporter family 14 148 3.6E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 THSYN_RS07010 1ce3c7ba7fc88f2d3a6938e6fb61251e 356 Pfam PF00892 EamA-like transporter family 159 289 1.2E-7 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 THSYN_RS07010 1ce3c7ba7fc88f2d3a6938e6fb61251e 356 SUPERFAMILY SSF103481 202 295 1.83E-10 T 29-03-2018 THSYN_RS07010 1ce3c7ba7fc88f2d3a6938e6fb61251e 356 SUPERFAMILY SSF103481 69 151 3.53E-12 T 29-03-2018 THSYN_RS13145 ca73a564fafceab8b3973b8a35d9a1d9 889 Gene3D G3DSA:3.40.50.300 84 759 1.9E-23 T 29-03-2018 THSYN_RS13145 ca73a564fafceab8b3973b8a35d9a1d9 889 SUPERFAMILY SSF52540 501 720 3.15E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13145 ca73a564fafceab8b3973b8a35d9a1d9 889 SUPERFAMILY SSF52540 84 216 3.15E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13145 ca73a564fafceab8b3973b8a35d9a1d9 889 Pfam PF02463 RecF/RecN/SMC N terminal domain 85 722 3.1E-18 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal THSYN_RS25260 7a56c363219bbd89d2be915b767f3cd7 163 Pfam PF01724 Domain of unknown function DUF29 7 152 2.4E-46 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS08260 2ef746f9492734a9b1d338f1e488511f 377 Pfam PF07589 PEP-CTERM motif 353 375 1.8E-7 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS08260 2ef746f9492734a9b1d338f1e488511f 377 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 353 376 2.3E-6 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS20780 250a12f2d727c46ad33701ac16b8a18f 206 Gene3D G3DSA:3.10.450.50 4 76 3.3E-14 T 29-03-2018 THSYN_RS20780 250a12f2d727c46ad33701ac16b8a18f 206 Pfam PF02810 SEC-C motif 56 73 1.2E-8 T 29-03-2018 IPR004027 SEC-C motif THSYN_RS20780 250a12f2d727c46ad33701ac16b8a18f 206 SUPERFAMILY SSF103642 53 74 5.56E-8 T 29-03-2018 THSYN_RS23725 ec2805003746418920449e8613391ca4 507 Pfam PF00583 Acetyltransferase (GNAT) family 221 303 3.6E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS23725 ec2805003746418920449e8613391ca4 507 Gene3D G3DSA:3.40.630.30 177 327 3.1E-26 T 29-03-2018 THSYN_RS23725 ec2805003746418920449e8613391ca4 507 SUPERFAMILY SSF55729 172 314 8.44E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS09325 0694ff87619e9ae35db77e0fc68c8860 410 Gene3D G3DSA:3.40.50.20 4 122 6.6E-4 T 29-03-2018 THSYN_RS09325 0694ff87619e9ae35db77e0fc68c8860 410 SUPERFAMILY SSF56059 119 306 2.98E-17 T 29-03-2018 THSYN_RS09325 0694ff87619e9ae35db77e0fc68c8860 410 Gene3D G3DSA:3.30.470.20 123 385 1.5E-17 T 29-03-2018 THSYN_RS10980 85b9bb018f876aabbee52beeea60d71f 163 Pfam PF02674 Colicin V production protein 4 142 6.7E-37 T 29-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 THSYN_RS31125 a56a0cc04781c9b07531116c115b7d5b 593 Pfam PF13531 Bacterial extracellular solute-binding protein 44 331 3.7E-29 T 29-03-2018 THSYN_RS31125 a56a0cc04781c9b07531116c115b7d5b 593 SUPERFAMILY SSF53850 48 334 3.09E-14 T 29-03-2018 THSYN_RS31125 a56a0cc04781c9b07531116c115b7d5b 593 Gene3D G3DSA:3.40.190.10 208 346 1.2E-11 T 29-03-2018 THSYN_RS31125 a56a0cc04781c9b07531116c115b7d5b 593 Gene3D G3DSA:3.40.50.410 380 593 1.4E-24 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS31125 a56a0cc04781c9b07531116c115b7d5b 593 Pfam PF00092 von Willebrand factor type A domain 387 571 3.6E-8 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS31125 a56a0cc04781c9b07531116c115b7d5b 593 SMART SM00327 384 586 7.2E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS31125 a56a0cc04781c9b07531116c115b7d5b 593 SUPERFAMILY SSF53300 386 590 1.45E-18 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS17860 79c2c0b4485179a0c2741ecaa461bad3 71 Gene3D G3DSA:3.30.2390.10 4 71 1.1E-12 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS17860 79c2c0b4485179a0c2741ecaa461bad3 71 SUPERFAMILY SSF143100 8 60 3.4E-11 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS10570 52957106c5f1b31ce5f93cd0268eea81 67 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 32 54 3.9E-4 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS28860 b6dc664a47cad5c7989fec0237b02fb8 614 Gene3D G3DSA:1.25.40.10 1 111 0.0013 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS28860 b6dc664a47cad5c7989fec0237b02fb8 614 Gene3D G3DSA:1.25.40.10 114 299 1.1E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS28860 b6dc664a47cad5c7989fec0237b02fb8 614 SUPERFAMILY SSF48452 256 290 7.6E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS28860 b6dc664a47cad5c7989fec0237b02fb8 614 SUPERFAMILY SSF48452 439 538 7.6E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS28860 b6dc664a47cad5c7989fec0237b02fb8 614 Gene3D G3DSA:1.25.40.10 434 593 6.4E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS28860 b6dc664a47cad5c7989fec0237b02fb8 614 SMART SM00028 484 517 72.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS28860 b6dc664a47cad5c7989fec0237b02fb8 614 SMART SM00028 147 180 0.85 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS28860 b6dc664a47cad5c7989fec0237b02fb8 614 SMART SM00028 256 289 51.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS28860 b6dc664a47cad5c7989fec0237b02fb8 614 SUPERFAMILY SSF48452 122 290 2.75E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS03425 22bb2518f9658f3d6678e3a105aba8c3 1195 Gene3D G3DSA:3.40.50.300 470 659 9.8E-31 T 29-03-2018 THSYN_RS03425 22bb2518f9658f3d6678e3a105aba8c3 1195 SUPERFAMILY SSF52540 85 291 3.18E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03425 22bb2518f9658f3d6678e3a105aba8c3 1195 SMART SM00490 537 622 1.6E-23 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS03425 22bb2518f9658f3d6678e3a105aba8c3 1195 SUPERFAMILY SSF52540 523 662 1.15E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03425 22bb2518f9658f3d6678e3a105aba8c3 1195 SUPERFAMILY SSF52540 224 292 1.15E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03425 22bb2518f9658f3d6678e3a105aba8c3 1195 SUPERFAMILY SSF52540 472 496 1.15E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03425 22bb2518f9658f3d6678e3a105aba8c3 1195 Pfam PF00271 Helicase conserved C-terminal domain 523 622 1.5E-20 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS03425 22bb2518f9658f3d6678e3a105aba8c3 1195 SMART SM00487 100 310 1.4E-18 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS03425 22bb2518f9658f3d6678e3a105aba8c3 1195 Pfam PF13020 Domain of unknown function (DUF3883) 1080 1164 2.6E-16 T 29-03-2018 IPR024975 Domain of unknown function DUF3883 THSYN_RS03425 22bb2518f9658f3d6678e3a105aba8c3 1195 Pfam PF00176 SNF2 family N-terminal domain 125 358 9.6E-17 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THSYN_RS03425 22bb2518f9658f3d6678e3a105aba8c3 1195 Gene3D G3DSA:3.40.50.300 97 462 3.7E-27 T 29-03-2018 THSYN_RS12780 734fc360f6d196d0e41832e1677cdf35 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 255 279 3.1E-11 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS12780 734fc360f6d196d0e41832e1677cdf35 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 348 367 3.1E-11 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS12780 734fc360f6d196d0e41832e1677cdf35 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 146 165 3.1E-11 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS12780 734fc360f6d196d0e41832e1677cdf35 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 400 426 3.1E-11 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS12780 734fc360f6d196d0e41832e1677cdf35 508 Pfam PF00361 Proton-conducting membrane transporter 141 438 7.9E-53 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS08835 31e027e846299703b5dae778cba7ab2b 255 Pfam PF01476 LysM domain 47 89 3.1E-10 T 29-03-2018 IPR018392 LysM domain THSYN_RS08835 31e027e846299703b5dae778cba7ab2b 255 Gene3D G3DSA:2.70.70.10 102 254 8.2E-29 T 29-03-2018 THSYN_RS08835 31e027e846299703b5dae778cba7ab2b 255 SMART SM00257 46 90 5.7E-10 T 29-03-2018 IPR018392 LysM domain THSYN_RS08835 31e027e846299703b5dae778cba7ab2b 255 SUPERFAMILY SSF51261 47 251 1.57E-35 T 29-03-2018 IPR011055 Duplicated hybrid motif THSYN_RS08835 31e027e846299703b5dae778cba7ab2b 255 Pfam PF01551 Peptidase family M23 155 247 4.7E-23 T 29-03-2018 IPR016047 Peptidase M23 THSYN_RS08835 31e027e846299703b5dae778cba7ab2b 255 Gene3D G3DSA:3.10.350.10 33 101 1.1E-13 T 29-03-2018 THSYN_RS16275 2955dcb140b0aaae925d078d9f7646a6 385 Gene3D G3DSA:3.40.50.300 188 373 1.3E-14 T 29-03-2018 THSYN_RS16275 2955dcb140b0aaae925d078d9f7646a6 385 SUPERFAMILY SSF53795 190 248 2.47E-10 T 29-03-2018 THSYN_RS11715 154c7a2529941a3ecb6421233711676c 711 Gene3D G3DSA:3.40.50.2000 478 704 1.7E-28 T 29-03-2018 THSYN_RS11715 154c7a2529941a3ecb6421233711676c 711 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 224 706 3.4E-152 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THSYN_RS11715 154c7a2529941a3ecb6421233711676c 711 Pfam PF00534 Glycosyl transferases group 1 516 662 8.5E-8 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS11715 154c7a2529941a3ecb6421233711676c 711 Pfam PF08323 Starch synthase catalytic domain 224 464 1.6E-60 T 29-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THSYN_RS11715 154c7a2529941a3ecb6421233711676c 711 Hamap MF_00484 Glycogen synthase [glgA]. 222 708 37.721 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THSYN_RS11715 154c7a2529941a3ecb6421233711676c 711 SUPERFAMILY SSF53756 216 710 9.77E-104 T 29-03-2018 THSYN_RS24315 e3f4768b2228698eb69020be4c21e78d 262 SUPERFAMILY SSF50630 163 250 4.24E-11 T 29-03-2018 IPR021109 Aspartic peptidase domain THSYN_RS24315 e3f4768b2228698eb69020be4c21e78d 262 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 164 175 - T 29-03-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 THSYN_RS24315 e3f4768b2228698eb69020be4c21e78d 262 Pfam PF13650 Aspartyl protease 163 241 3.9E-16 T 29-03-2018 THSYN_RS24315 e3f4768b2228698eb69020be4c21e78d 262 Gene3D G3DSA:2.40.70.10 137 253 1.4E-11 T 29-03-2018 IPR021109 Aspartic peptidase domain THSYN_RS08405 d1b30db252ccd03cc9c3ded4b88c2a33 115 TIGRFAM TIGR03382 GC_trans_RRR: Myxococcales GC_trans_RRR domain 91 111 0.0034 T 29-03-2018 IPR017756 Transmembrane Gly-Cys-Arg, conserved site THSYN_RS13385 eeb364292e8bdc42b2d68cab7b121e94 113 Pfam PF03831 PhnA domain 46 113 6.7E-33 T 29-03-2018 IPR013988 PhnA protein, C-terminal THSYN_RS13385 eeb364292e8bdc42b2d68cab7b121e94 113 Pfam PF08274 PhnA Zinc-Ribbon 3 32 1.7E-14 T 29-03-2018 IPR013987 PhnA protein, N-terminal THSYN_RS13385 eeb364292e8bdc42b2d68cab7b121e94 113 Gene3D G3DSA:2.20.25.10 2 39 3.6E-16 T 29-03-2018 THSYN_RS13385 eeb364292e8bdc42b2d68cab7b121e94 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 3 113 5.3E-48 T 29-03-2018 IPR004624 PhnA protein THSYN_RS13385 eeb364292e8bdc42b2d68cab7b121e94 113 Gene3D G3DSA:2.30.30.40 45 112 9.6E-36 T 29-03-2018 THSYN_RS13385 eeb364292e8bdc42b2d68cab7b121e94 113 SUPERFAMILY SSF82057 41 113 2.66E-28 T 29-03-2018 THSYN_RS13385 eeb364292e8bdc42b2d68cab7b121e94 113 SUPERFAMILY SSF57783 3 35 1.07E-13 T 29-03-2018 THSYN_RS13160 94fd10212ee75990f59f20683b8de4d3 704 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 152 573 8.8E-48 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain THSYN_RS13160 94fd10212ee75990f59f20683b8de4d3 704 Gene3D G3DSA:3.10.105.10 418 630 2.9E-41 T 29-03-2018 THSYN_RS13160 94fd10212ee75990f59f20683b8de4d3 704 SUPERFAMILY SSF53850 22 114 4.96E-83 T 29-03-2018 THSYN_RS13160 94fd10212ee75990f59f20683b8de4d3 704 SUPERFAMILY SSF53850 153 647 4.96E-83 T 29-03-2018 THSYN_RS13160 94fd10212ee75990f59f20683b8de4d3 704 Gene3D G3DSA:3.90.76.10 66 234 2.7E-19 T 29-03-2018 THSYN_RS13160 94fd10212ee75990f59f20683b8de4d3 704 Gene3D G3DSA:3.40.190.10 235 417 1.3E-27 T 29-03-2018 THSYN_RS13160 94fd10212ee75990f59f20683b8de4d3 704 PIRSF PIRSF002741 22 69 220.0 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 THSYN_RS13160 94fd10212ee75990f59f20683b8de4d3 704 PIRSF PIRSF002741 151 656 4.2E-50 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 THSYN_RS16485 7c9902368b453883b24d73f4e7336609 240 Pfam PF12800 4Fe-4S binding domain 11 25 0.039 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS16485 7c9902368b453883b24d73f4e7336609 240 Pfam PF13247 4Fe-4S dicluster domain 66 167 6.1E-23 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS16485 7c9902368b453883b24d73f4e7336609 240 SUPERFAMILY SSF54862 1 208 4.5E-66 T 29-03-2018 THSYN_RS16485 7c9902368b453883b24d73f4e7336609 240 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 106 117 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS16485 7c9902368b453883b24d73f4e7336609 240 Gene3D G3DSA:3.30.70.20 127 226 8.6E-23 T 29-03-2018 THSYN_RS16485 7c9902368b453883b24d73f4e7336609 240 Gene3D G3DSA:3.30.70.20 88 126 3.3E-22 T 29-03-2018 THSYN_RS16485 7c9902368b453883b24d73f4e7336609 240 Gene3D G3DSA:3.30.70.20 2 87 2.3E-20 T 29-03-2018 THSYN_RS30465 115627ec4817d217bc799ed93f1a524f 802 Gene3D G3DSA:1.10.3210.10 87 260 2.2E-7 T 29-03-2018 THSYN_RS30465 115627ec4817d217bc799ed93f1a524f 802 Gene3D G3DSA:1.10.10.10 261 488 8.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS30465 115627ec4817d217bc799ed93f1a524f 802 SMART SM00471 116 284 0.0089 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS30465 115627ec4817d217bc799ed93f1a524f 802 Pfam PF07514 Putative helicase 57 373 4.9E-97 T 29-03-2018 IPR011119 Uncharacterised domain, helicase/relaxase, putative THSYN_RS00715 8d1253b8c053fdad1e6bde98135f5f8b 873 Gene3D G3DSA:2.60.120.260 20 178 1.1E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS00715 8d1253b8c053fdad1e6bde98135f5f8b 873 SUPERFAMILY SSF51445 617 706 1.12E-40 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS00715 8d1253b8c053fdad1e6bde98135f5f8b 873 SUPERFAMILY SSF51445 224 408 1.12E-40 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS00715 8d1253b8c053fdad1e6bde98135f5f8b 873 SUPERFAMILY SSF49785 21 170 1.19E-28 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS00715 8d1253b8c053fdad1e6bde98135f5f8b 873 SUPERFAMILY SSF101447 730 735 6.28E-5 T 29-03-2018 THSYN_RS00715 8d1253b8c053fdad1e6bde98135f5f8b 873 Pfam PF02018 Carbohydrate binding domain 22 156 7.8E-18 T 29-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 THSYN_RS00715 8d1253b8c053fdad1e6bde98135f5f8b 873 Gene3D G3DSA:3.20.20.80 198 717 1.1E-44 T 29-03-2018 THSYN_RS00715 8d1253b8c053fdad1e6bde98135f5f8b 873 Gene3D G3DSA:2.60.120.260 718 873 2.8E-6 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS00715 8d1253b8c053fdad1e6bde98135f5f8b 873 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 228 408 8.3E-18 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 Gene3D G3DSA:3.20.20.450 451 696 3.9E-37 T 29-03-2018 IPR001633 EAL domain THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 SMART SM00267 258 437 1.4E-7 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 SUPERFAMILY SSF52172 27 129 8.5E-5 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 Gene3D G3DSA:3.40.50.2300 135 275 1.2E-28 T 29-03-2018 THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 Pfam PF00563 EAL domain 457 684 3.8E-33 T 29-03-2018 IPR001633 EAL domain THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 SUPERFAMILY SSF52172 137 270 4.7E-32 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 SUPERFAMILY SSF55073 275 435 6.04E-13 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 SMART SM00052 449 689 3.5E-30 T 29-03-2018 IPR001633 EAL domain THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 Pfam PF00072 Response regulator receiver domain 140 251 1.1E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 Gene3D G3DSA:3.40.50.2300 5 130 2.4E-6 T 29-03-2018 THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 Gene3D G3DSA:3.30.70.270 276 436 2.1E-18 T 29-03-2018 THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 SUPERFAMILY SSF141868 457 685 9.29E-36 T 29-03-2018 IPR001633 EAL domain THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 SMART SM00448 138 251 2.3E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS11670 7830d46c05c3407fe18487124af5ad55 698 Pfam PF00990 Diguanylate cyclase, GGDEF domain 271 433 5.8E-7 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS27885 9d3aca7346aca79175835295073b1792 190 Gene3D G3DSA:3.90.1570.10 2 186 1.0E-36 T 29-03-2018 THSYN_RS27885 9d3aca7346aca79175835295073b1792 190 Pfam PF05685 Putative restriction endonuclease 13 179 4.3E-29 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS27885 9d3aca7346aca79175835295073b1792 190 SUPERFAMILY SSF52980 8 183 1.82E-22 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS22720 ff017b998ecece4317db9a2b43339fbc 112 SUPERFAMILY SSF69721 1 105 1.15E-28 T 29-03-2018 IPR025526 DsrC-like domain THSYN_RS22720 ff017b998ecece4317db9a2b43339fbc 112 Gene3D G3DSA:1.10.10.370 41 106 7.3E-22 T 29-03-2018 THSYN_RS22720 ff017b998ecece4317db9a2b43339fbc 112 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 3 105 4.5E-28 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE THSYN_RS22720 ff017b998ecece4317db9a2b43339fbc 112 Gene3D G3DSA:3.30.1420.10 3 40 3.9E-16 T 29-03-2018 THSYN_RS22720 ff017b998ecece4317db9a2b43339fbc 112 Pfam PF04358 DsrC like protein 4 105 1.0E-31 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE THSYN_RS22720 ff017b998ecece4317db9a2b43339fbc 112 PIRSF PIRSF006223 3 109 3.9E-29 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE THSYN_RS13200 4fb69cbb8ab4c80ee37c2da6dd1ac25d 929 Gene3D G3DSA:3.40.50.300 560 751 2.0E-4 T 29-03-2018 THSYN_RS13200 4fb69cbb8ab4c80ee37c2da6dd1ac25d 929 PRINTS PR00364 Disease resistance protein signature 593 608 1.3E-5 T 29-03-2018 THSYN_RS13200 4fb69cbb8ab4c80ee37c2da6dd1ac25d 929 PRINTS PR00364 Disease resistance protein signature 779 793 1.3E-5 T 29-03-2018 THSYN_RS13200 4fb69cbb8ab4c80ee37c2da6dd1ac25d 929 PRINTS PR00364 Disease resistance protein signature 675 689 1.3E-5 T 29-03-2018 THSYN_RS13200 4fb69cbb8ab4c80ee37c2da6dd1ac25d 929 SUPERFAMILY SSF52540 568 822 3.52E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 Pfam PF01751 Toprim domain 4 134 4.7E-9 T 29-03-2018 IPR006171 TOPRIM domain THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 Gene3D G3DSA:1.10.460.10 494 781 6.1E-25 T 29-03-2018 THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 Gene3D G3DSA:1.10.460.10 155 343 1.2E-32 T 29-03-2018 THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 Pfam PF01131 DNA topoisomerase 154 602 7.0E-101 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 Pfam PF13342 C-terminal repeat of topoisomerase 683 742 9.0E-23 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 SUPERFAMILY SSF56712 3 443 8.76E-151 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 SUPERFAMILY SSF56712 470 619 8.76E-151 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 SMART SM00436 126 216 1.7E-26 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 SMART SM00493 2 126 8.3E-6 T 29-03-2018 IPR006171 TOPRIM domain THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 Gene3D G3DSA:3.30.65.10 782 825 0.13 T 29-03-2018 THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 303 318 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 Gene3D G3DSA:2.70.20.10 356 493 2.2E-19 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 Gene3D G3DSA:3.40.50.140 2 154 2.5E-36 T 29-03-2018 THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 SMART SM00437 266 570 2.9E-66 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 309 318 2.2E-21 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 2.2E-21 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 389 405 2.2E-21 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 2.2E-21 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THSYN_RS11730 02d499d767bf8b1328e8d72076762ba5 888 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 533 547 2.2E-21 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THSYN_RS13450 43ea87b8c95aa38f2fb376be36e0d9ea 79 Gene3D G3DSA:3.30.2390.10 4 74 1.5E-9 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS13450 43ea87b8c95aa38f2fb376be36e0d9ea 79 SUPERFAMILY SSF143100 13 60 1.05E-12 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS10400 024ff1180c88574280a347afb5dff499 328 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 161 326 4.1E-30 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 THSYN_RS10400 024ff1180c88574280a347afb5dff499 328 SUPERFAMILY SSF51735 5 159 3.56E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS10400 024ff1180c88574280a347afb5dff499 328 Gene3D G3DSA:3.90.110.10 160 326 4.2E-47 T 29-03-2018 THSYN_RS10400 024ff1180c88574280a347afb5dff499 328 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 5 323 8.6E-135 T 29-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 THSYN_RS10400 024ff1180c88574280a347afb5dff499 328 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 145 6.5E-34 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 THSYN_RS10400 024ff1180c88574280a347afb5dff499 328 Gene3D G3DSA:3.40.50.720 7 159 9.9E-24 T 29-03-2018 THSYN_RS10400 024ff1180c88574280a347afb5dff499 328 PIRSF PIRSF000102 2 327 9.0E-60 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THSYN_RS10400 024ff1180c88574280a347afb5dff499 328 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 328 53.685 T 29-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 THSYN_RS10400 024ff1180c88574280a347afb5dff499 328 SUPERFAMILY SSF56327 161 327 7.26E-56 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 THSYN_RS26425 bfb1164fbe7b208b8109dc5bf0ccc96f 214 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 13 214 30.001 T 29-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 THSYN_RS26425 bfb1164fbe7b208b8109dc5bf0ccc96f 214 Gene3D G3DSA:1.20.1260.10 44 187 4.0E-19 T 29-03-2018 IPR012347 Ferritin-related THSYN_RS26425 bfb1164fbe7b208b8109dc5bf0ccc96f 214 SUPERFAMILY SSF47240 50 187 6.86E-16 T 29-03-2018 IPR009078 Ferritin-like superfamily THSYN_RS26425 bfb1164fbe7b208b8109dc5bf0ccc96f 214 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 52 214 7.9E-41 T 29-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 THSYN_RS00750 1ec68d6b37c757424ec8c91d10c2b48d 1024 Gene3D G3DSA:3.40.50.1460 442 690 2.2E-26 T 29-03-2018 THSYN_RS00750 1ec68d6b37c757424ec8c91d10c2b48d 1024 Pfam PF12770 CHAT domain 389 683 1.2E-27 T 29-03-2018 IPR024983 CHAT domain THSYN_RS32825 765b3c21026e5e9d85a55c1fe6482fce 500 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 21 495 4.4E-220 T 29-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath THSYN_RS32825 765b3c21026e5e9d85a55c1fe6482fce 500 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 71 495 2.1E-190 T 29-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath THSYN_RS29310 49550505f66eeeb1ff1590544d4758ae 346 Pfam PF11740 Plasmid replication region DNA-binding N-term 7 116 1.4E-19 T 29-03-2018 IPR021104 KfrA, N-terminal DNA-binding domain THSYN_RS29310 49550505f66eeeb1ff1590544d4758ae 346 Gene3D G3DSA:1.20.5.340 30 174 2.5E-7 T 29-03-2018 THSYN_RS29310 49550505f66eeeb1ff1590544d4758ae 346 Gene3D G3DSA:1.10.287.620 175 332 2.4E-4 T 29-03-2018 THSYN_RS25825 756397641c3660270994c684eabc7af3 832 Gene3D G3DSA:1.10.260.40 1 67 5.9E-15 T 29-03-2018 THSYN_RS25825 756397641c3660270994c684eabc7af3 832 Pfam PF13560 Helix-turn-helix domain 6 61 2.4E-13 T 29-03-2018 THSYN_RS25825 756397641c3660270994c684eabc7af3 832 SUPERFAMILY SSF53335 654 700 1.46E-17 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS25825 756397641c3660270994c684eabc7af3 832 SUPERFAMILY SSF53335 143 225 1.46E-17 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS25825 756397641c3660270994c684eabc7af3 832 SUPERFAMILY SSF53335 567 601 1.46E-17 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS25825 756397641c3660270994c684eabc7af3 832 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 595 601 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS25825 756397641c3660270994c684eabc7af3 832 Gene3D G3DSA:3.40.50.150 165 730 4.4E-36 T 29-03-2018 THSYN_RS25825 756397641c3660270994c684eabc7af3 832 SUPERFAMILY SSF47413 1 63 1.3E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS25825 756397641c3660270994c684eabc7af3 832 SMART SM00530 6 61 1.3E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS25825 756397641c3660270994c684eabc7af3 832 Pfam PF01555 DNA methylase 164 215 4.9E-7 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THSYN_RS22315 daf0e99ce2864a92bbdb125941aaeebc 174 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 7 157 2.7E-46 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THSYN_RS22315 daf0e99ce2864a92bbdb125941aaeebc 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 86 102 5.9E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THSYN_RS22315 daf0e99ce2864a92bbdb125941aaeebc 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 110 129 5.9E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THSYN_RS22315 daf0e99ce2864a92bbdb125941aaeebc 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 64 80 5.9E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THSYN_RS22315 daf0e99ce2864a92bbdb125941aaeebc 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 141 153 5.9E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THSYN_RS22315 daf0e99ce2864a92bbdb125941aaeebc 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 8 21 5.9E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THSYN_RS22315 daf0e99ce2864a92bbdb125941aaeebc 174 SUPERFAMILY SSF53098 6 159 3.49E-49 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS22315 daf0e99ce2864a92bbdb125941aaeebc 174 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 116 150 - T 29-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 THSYN_RS22315 daf0e99ce2864a92bbdb125941aaeebc 174 Gene3D G3DSA:3.30.420.10 5 160 7.7E-44 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS22315 daf0e99ce2864a92bbdb125941aaeebc 174 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 5 156 42.705 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THSYN_RS22315 daf0e99ce2864a92bbdb125941aaeebc 174 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 7 153 3.5E-48 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THSYN_RS14560 5b8b4ec8cdd090006ad002626044e4be 160 Pfam PF04461 Protein of unknown function (DUF520) 2 159 1.7E-64 T 29-03-2018 IPR007551 Protein of unknown function DUF520 THSYN_RS14560 5b8b4ec8cdd090006ad002626044e4be 160 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 160 28.8 T 29-03-2018 IPR007551 Protein of unknown function DUF520 THSYN_RS14560 5b8b4ec8cdd090006ad002626044e4be 160 SUPERFAMILY SSF89963 2 83 8.63E-33 T 29-03-2018 IPR007551 Protein of unknown function DUF520 THSYN_RS14560 5b8b4ec8cdd090006ad002626044e4be 160 Gene3D G3DSA:3.30.70.990 10 94 4.9E-34 T 29-03-2018 IPR035570 UPF0234 N-terminal domain THSYN_RS14560 5b8b4ec8cdd090006ad002626044e4be 160 SUPERFAMILY SSF89963 88 160 3.14E-26 T 29-03-2018 IPR007551 Protein of unknown function DUF520 THSYN_RS14560 5b8b4ec8cdd090006ad002626044e4be 160 Gene3D G3DSA:3.30.70.860 95 159 2.3E-29 T 29-03-2018 IPR035571 UPF0234/UPF0381 domain THSYN_RS32780 62db4c2bbad0d89721997a116852b381 915 Pfam PF13091 PLD-like domain 20 176 1.1E-12 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THSYN_RS32780 62db4c2bbad0d89721997a116852b381 915 SUPERFAMILY SSF56024 104 182 2.63E-6 T 29-03-2018 THSYN_RS32780 62db4c2bbad0d89721997a116852b381 915 Pfam PF00271 Helicase conserved C-terminal domain 751 807 2.7E-11 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS32780 62db4c2bbad0d89721997a116852b381 915 Gene3D G3DSA:3.30.870.10 16 186 9.4E-7 T 29-03-2018 THSYN_RS32780 62db4c2bbad0d89721997a116852b381 915 Gene3D G3DSA:3.40.50.300 677 844 2.1E-22 T 29-03-2018 THSYN_RS32780 62db4c2bbad0d89721997a116852b381 915 Pfam PF00176 SNF2 family N-terminal domain 251 435 4.2E-14 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THSYN_RS32780 62db4c2bbad0d89721997a116852b381 915 SUPERFAMILY SSF52540 675 860 3.42E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS32780 62db4c2bbad0d89721997a116852b381 915 SUPERFAMILY SSF52540 369 419 3.42E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS32780 62db4c2bbad0d89721997a116852b381 915 SMART SM00490 718 807 1.9E-9 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS32780 62db4c2bbad0d89721997a116852b381 915 Gene3D G3DSA:3.40.50.10810 210 676 1.1E-23 T 29-03-2018 THSYN_RS32780 62db4c2bbad0d89721997a116852b381 915 SMART SM00487 223 442 1.6E-12 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS32780 62db4c2bbad0d89721997a116852b381 915 SUPERFAMILY SSF52540 217 435 1.96E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03015 53a134aa9be422b326e2cc1b25b7cf02 249 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 24 176 4.9E-28 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal THSYN_RS03015 53a134aa9be422b326e2cc1b25b7cf02 249 SUPERFAMILY SSF53901 23 146 6.81E-9 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS03015 53a134aa9be422b326e2cc1b25b7cf02 249 Gene3D G3DSA:3.40.47.10 6 148 1.2E-8 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 Gene3D G3DSA:3.50.50.60 259 334 3.0E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 344 447 2.5E-16 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 SUPERFAMILY SSF55424 337 460 4.64E-26 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 Pfam PF00581 Rhodanese-like domain 470 561 4.8E-8 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 SMART SM00450 469 567 3.4E-9 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 SUPERFAMILY SSF52821 450 561 7.6E-24 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 SUPERFAMILY SSF51905 209 359 1.37E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 SUPERFAMILY SSF51905 1 180 1.37E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 Gene3D G3DSA:3.50.50.60 116 257 2.3E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 Gene3D G3DSA:3.50.50.60 2 115 2.8E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.8E-13 T 29-03-2018 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 4.8E-13 T 29-03-2018 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 188 4.8E-13 T 29-03-2018 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 249 263 4.8E-13 T 29-03-2018 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 297 1.2E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 Gene3D G3DSA:3.30.390.30 340 468 4.5E-25 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.1E-23 T 29-03-2018 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.1E-23 T 29-03-2018 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 264 1.1E-23 T 29-03-2018 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 116 134 1.1E-23 T 29-03-2018 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 1.1E-23 T 29-03-2018 THSYN_RS19260 f4f42233ba27f0c594dd2739cb0bee69 567 Gene3D G3DSA:3.40.250.10 469 563 5.3E-17 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS03410 8c97eb5dcc84ccd9d65f7d25512780be 287 SUPERFAMILY SSF51735 4 285 3.19E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS03410 8c97eb5dcc84ccd9d65f7d25512780be 287 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 211 1.6E-9 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THSYN_RS03410 8c97eb5dcc84ccd9d65f7d25512780be 287 Gene3D G3DSA:3.40.50.720 4 287 4.6E-36 T 29-03-2018 THSYN_RS13545 8d05d1b00720667acb2e0cc6c535f224 77 Gene3D G3DSA:4.10.640.10 1 77 1.2E-29 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13545 8d05d1b00720667acb2e0cc6c535f224 77 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 1.3E-18 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13545 8d05d1b00720667acb2e0cc6c535f224 77 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 1.3E-18 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13545 8d05d1b00720667acb2e0cc6c535f224 77 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 1.3E-18 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13545 8d05d1b00720667acb2e0cc6c535f224 77 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 1.3E-18 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13545 8d05d1b00720667acb2e0cc6c535f224 77 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 24 74 5.0E-20 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13545 8d05d1b00720667acb2e0cc6c535f224 77 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13545 8d05d1b00720667acb2e0cc6c535f224 77 TIGRFAM TIGR00165 S18: ribosomal protein bS18 7 75 3.1E-36 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13545 8d05d1b00720667acb2e0cc6c535f224 77 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 5 76 21.313 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13545 8d05d1b00720667acb2e0cc6c535f224 77 SUPERFAMILY SSF46911 4 76 3.01E-28 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS13545 8d05d1b00720667acb2e0cc6c535f224 77 Pfam PF01084 Ribosomal protein S18 22 71 1.8E-24 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS25370 940bdfffbbbb3ae8cbc66fce63e60bdd 124 SUPERFAMILY SSF46785 5 107 1.62E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25370 940bdfffbbbb3ae8cbc66fce63e60bdd 124 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 55 1.0E-11 T 29-03-2018 THSYN_RS25370 940bdfffbbbb3ae8cbc66fce63e60bdd 124 TIGRFAM TIGR04176 MarR_EPS: EPS-associated transcriptional regulator, MarR family 8 107 3.0E-43 T 29-03-2018 IPR026433 EPS-associated transcriptional regulator, MarR family THSYN_RS25370 940bdfffbbbb3ae8cbc66fce63e60bdd 124 Gene3D G3DSA:1.10.10.10 1 110 6.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS04515 14efdfe83bf3fc1743a18cbd1e93061c 505 Gene3D G3DSA:1.10.287.1120 466 505 1.3E-8 T 29-03-2018 THSYN_RS04515 14efdfe83bf3fc1743a18cbd1e93061c 505 Pfam PF01420 Type I restriction modification DNA specificity domain 57 237 1.1E-11 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS04515 14efdfe83bf3fc1743a18cbd1e93061c 505 Pfam PF01420 Type I restriction modification DNA specificity domain 431 478 2.2E-5 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS04515 14efdfe83bf3fc1743a18cbd1e93061c 505 Gene3D G3DSA:3.90.220.20 16 236 5.3E-28 T 29-03-2018 THSYN_RS04515 14efdfe83bf3fc1743a18cbd1e93061c 505 Gene3D G3DSA:3.90.220.20 276 465 3.9E-19 T 29-03-2018 THSYN_RS04515 14efdfe83bf3fc1743a18cbd1e93061c 505 SUPERFAMILY SSF116734 275 297 2.45E-35 T 29-03-2018 THSYN_RS04515 14efdfe83bf3fc1743a18cbd1e93061c 505 SUPERFAMILY SSF116734 55 238 2.45E-35 T 29-03-2018 THSYN_RS04515 14efdfe83bf3fc1743a18cbd1e93061c 505 SUPERFAMILY SSF116734 314 493 1.26E-22 T 29-03-2018 THSYN_RS31715 7be7040ad5e5a850569bf9edd3f9d3a7 284 Pfam PF00520 Ion transport protein 33 240 8.3E-32 T 29-03-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 THSYN_RS31715 7be7040ad5e5a850569bf9edd3f9d3a7 284 Gene3D G3DSA:1.10.287.70 158 206 9.5E-14 T 29-03-2018 THSYN_RS31715 7be7040ad5e5a850569bf9edd3f9d3a7 284 PRINTS PR00169 Potassium channel signature 67 90 5.0E-35 T 29-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 THSYN_RS31715 7be7040ad5e5a850569bf9edd3f9d3a7 284 PRINTS PR00169 Potassium channel signature 93 113 5.0E-35 T 29-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 THSYN_RS31715 7be7040ad5e5a850569bf9edd3f9d3a7 284 PRINTS PR00169 Potassium channel signature 216 242 5.0E-35 T 29-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 THSYN_RS31715 7be7040ad5e5a850569bf9edd3f9d3a7 284 PRINTS PR00169 Potassium channel signature 129 155 5.0E-35 T 29-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 THSYN_RS31715 7be7040ad5e5a850569bf9edd3f9d3a7 284 PRINTS PR00169 Potassium channel signature 158 181 5.0E-35 T 29-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 THSYN_RS31715 7be7040ad5e5a850569bf9edd3f9d3a7 284 PRINTS PR00169 Potassium channel signature 187 209 5.0E-35 T 29-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 THSYN_RS31715 7be7040ad5e5a850569bf9edd3f9d3a7 284 PRINTS PR00169 Potassium channel signature 25 53 5.0E-35 T 29-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 THSYN_RS31715 7be7040ad5e5a850569bf9edd3f9d3a7 284 SUPERFAMILY SSF81324 30 243 3.14E-51 T 29-03-2018 THSYN_RS31715 7be7040ad5e5a850569bf9edd3f9d3a7 284 Gene3D G3DSA:1.20.5.110 208 244 2.0E-13 T 29-03-2018 THSYN_RS31715 7be7040ad5e5a850569bf9edd3f9d3a7 284 Gene3D G3DSA:1.20.120.350 29 157 3.6E-27 T 29-03-2018 THSYN_RS04890 0f84301c18aafe23c925ed540575647c 354 Gene3D G3DSA:3.20.20.70 1 331 3.3E-105 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS04890 0f84301c18aafe23c925ed540575647c 354 PIRSF PIRSF001359 1 329 1.4E-80 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THSYN_RS04890 0f84301c18aafe23c925ed540575647c 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 3.0E-199 T 29-03-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 THSYN_RS04890 0f84301c18aafe23c925ed540575647c 354 SUPERFAMILY SSF51569 3 327 5.57E-105 T 29-03-2018 THSYN_RS04890 0f84301c18aafe23c925ed540575647c 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 327 8.9E-92 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THSYN_RS04890 0f84301c18aafe23c925ed540575647c 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 327 1.1E-95 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THSYN_RS04890 0f84301c18aafe23c925ed540575647c 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THSYN_RS01370 8bc0c624eb121f6d0ab7ed591f5d1abf 207 SUPERFAMILY SSF53163 6 163 2.33E-45 T 29-03-2018 IPR023430 Peptidase HybD-like domain THSYN_RS01370 8bc0c624eb121f6d0ab7ed591f5d1abf 207 PRINTS PR00446 Hydrogen uptake protein signature 7 19 2.9E-32 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS01370 8bc0c624eb121f6d0ab7ed591f5d1abf 207 PRINTS PR00446 Hydrogen uptake protein signature 71 87 2.9E-32 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS01370 8bc0c624eb121f6d0ab7ed591f5d1abf 207 PRINTS PR00446 Hydrogen uptake protein signature 60 70 2.9E-32 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS01370 8bc0c624eb121f6d0ab7ed591f5d1abf 207 PRINTS PR00446 Hydrogen uptake protein signature 39 56 2.9E-32 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS01370 8bc0c624eb121f6d0ab7ed591f5d1abf 207 PRINTS PR00446 Hydrogen uptake protein signature 19 30 2.9E-32 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS01370 8bc0c624eb121f6d0ab7ed591f5d1abf 207 Pfam PF01750 Hydrogenase maturation protease 24 152 4.9E-38 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS01370 8bc0c624eb121f6d0ab7ed591f5d1abf 207 TIGRFAM TIGR00140 hupD: hydrogenase expression/formation protein 7 158 1.6E-60 T 29-03-2018 IPR004419 Peptidase A31, hydrogenase expression/formation protein GO:0016485|GO:0046872 THSYN_RS01370 8bc0c624eb121f6d0ab7ed591f5d1abf 207 Gene3D G3DSA:3.40.50.1450 6 167 3.4E-45 T 29-03-2018 IPR023430 Peptidase HybD-like domain THSYN_RS01370 8bc0c624eb121f6d0ab7ed591f5d1abf 207 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 8 153 7.3E-44 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS18270 88616700832aa6d32e6159d0934b4097 382 SMART SM00382 31 343 5.5E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS18270 88616700832aa6d32e6159d0934b4097 382 Gene3D G3DSA:3.40.50.300 10 344 2.0E-25 T 29-03-2018 THSYN_RS18270 88616700832aa6d32e6159d0934b4097 382 PIRSF PIRSF029347 154 366 2.1E-12 T 29-03-2018 IPR014555 RecF-like THSYN_RS18270 88616700832aa6d32e6159d0934b4097 382 PIRSF PIRSF029347 10 144 1.5E-7 T 29-03-2018 IPR014555 RecF-like THSYN_RS18270 88616700832aa6d32e6159d0934b4097 382 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 34 330 1.4E-27 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS18270 88616700832aa6d32e6159d0934b4097 382 SUPERFAMILY SSF52540 10 137 9.61E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS18270 88616700832aa6d32e6159d0934b4097 382 SUPERFAMILY SSF52540 219 339 9.61E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07580 cae3dd6f504147ab8ae933f376082218 95 Gene3D G3DSA:1.10.150.250 10 95 1.6E-23 T 29-03-2018 THSYN_RS07580 cae3dd6f504147ab8ae933f376082218 95 SUPERFAMILY SSF109910 13 87 1.57E-21 T 29-03-2018 IPR005631 Flavinator of succinate dehydrogenase THSYN_RS07580 cae3dd6f504147ab8ae933f376082218 95 Pfam PF03937 Flavinator of succinate dehydrogenase 17 86 1.5E-22 T 29-03-2018 IPR005631 Flavinator of succinate dehydrogenase THSYN_RS03870 8f7ed936a5651d877e45d5ad04cede48 272 Pfam PF08543 Phosphomethylpyrimidine kinase 17 252 3.3E-65 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 THSYN_RS03870 8f7ed936a5651d877e45d5ad04cede48 272 Gene3D G3DSA:3.40.1190.20 4 263 5.3E-47 T 29-03-2018 IPR029056 Ribokinase-like THSYN_RS03870 8f7ed936a5651d877e45d5ad04cede48 272 SUPERFAMILY SSF53613 6 259 6.55E-61 T 29-03-2018 IPR029056 Ribokinase-like THSYN_RS14970 f54c560edae52181c6ac6432c7014836 1088 Gene3D G3DSA:3.40.50.1440 5 251 3.6E-7 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS14970 f54c560edae52181c6ac6432c7014836 1088 Pfam PF13809 Tubulin like 7 381 3.0E-40 T 29-03-2018 IPR025904 Tubulin-like THSYN_RS23160 490a755a52a0e796a91f00c75b20d5fb 290 Gene3D G3DSA:3.40.33.10 99 282 0.0019 T 29-03-2018 IPR014044 CAP domain THSYN_RS23160 490a755a52a0e796a91f00c75b20d5fb 290 SUPERFAMILY SSF55797 104 119 5.49E-8 T 29-03-2018 IPR014044 CAP domain THSYN_RS23160 490a755a52a0e796a91f00c75b20d5fb 290 SUPERFAMILY SSF55797 171 281 5.49E-8 T 29-03-2018 IPR014044 CAP domain THSYN_RS23160 490a755a52a0e796a91f00c75b20d5fb 290 Pfam PF00188 Cysteine-rich secretory protein family 169 273 7.5E-8 T 29-03-2018 IPR014044 CAP domain THSYN_RS00370 594118a9e88986d09c9ed957457d93ce 294 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 5 291 49.461 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 THSYN_RS00370 594118a9e88986d09c9ed957457d93ce 294 Pfam PF13714 Phosphoenolpyruvate phosphomutase 15 253 7.6E-49 T 29-03-2018 THSYN_RS00370 594118a9e88986d09c9ed957457d93ce 294 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 8 289 5.5E-127 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 THSYN_RS00370 594118a9e88986d09c9ed957457d93ce 294 SUPERFAMILY SSF51621 2 287 1.26E-100 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS00370 594118a9e88986d09c9ed957457d93ce 294 Gene3D G3DSA:3.20.20.60 3 294 2.6E-91 T 29-03-2018 THSYN_RS00370 594118a9e88986d09c9ed957457d93ce 294 ProSitePatterns PS00161 Isocitrate lyase signature. 121 126 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 THSYN_RS19860 92a755413df042e54ff46ad2f3efa26f 1933 Pfam PF00207 Alpha-2-macroglobulin family 1251 1336 1.9E-9 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 THSYN_RS19860 92a755413df042e54ff46ad2f3efa26f 1933 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 486 576 1.5E-17 T 29-03-2018 THSYN_RS19860 92a755413df042e54ff46ad2f3efa26f 1933 Gene3D G3DSA:2.60.40.10 1115 1299 3.0E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS19860 92a755413df042e54ff46ad2f3efa26f 1933 SMART SM01360 1249 1339 1.6E-18 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 THSYN_RS19860 92a755413df042e54ff46ad2f3efa26f 1933 SMART SM01359 1010 1167 1.1E-30 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 THSYN_RS19860 92a755413df042e54ff46ad2f3efa26f 1933 Pfam PF01835 MG2 domain 589 685 3.1E-18 T 29-03-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 THSYN_RS19860 92a755413df042e54ff46ad2f3efa26f 1933 Gene3D G3DSA:2.60.40.10 1306 1417 0.0053 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS19860 92a755413df042e54ff46ad2f3efa26f 1933 Gene3D G3DSA:2.60.40.10 493 687 0.04 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS19860 92a755413df042e54ff46ad2f3efa26f 1933 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 1015 1167 2.6E-17 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 THSYN_RS19860 92a755413df042e54ff46ad2f3efa26f 1933 Gene3D G3DSA:1.50.10.20 1477 1714 3.7E-5 T 29-03-2018 THSYN_RS23195 7d09f340909a023b79055781976113c7 353 SUPERFAMILY SSF54826 9 111 8.64E-14 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS23195 7d09f340909a023b79055781976113c7 353 Gene3D G3DSA:3.20.20.120 131 346 4.8E-48 T 29-03-2018 IPR029065 Enolase C-terminal domain-like THSYN_RS23195 7d09f340909a023b79055781976113c7 353 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 185 216 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 THSYN_RS23195 7d09f340909a023b79055781976113c7 353 Pfam PF13378 Enolase C-terminal domain-like 146 351 3.9E-33 T 29-03-2018 IPR029065 Enolase C-terminal domain-like THSYN_RS23195 7d09f340909a023b79055781976113c7 353 SUPERFAMILY SSF51604 125 346 2.23E-49 T 29-03-2018 IPR029065 Enolase C-terminal domain-like THSYN_RS23195 7d09f340909a023b79055781976113c7 353 SMART SM00922 142 235 4.6E-15 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal THSYN_RS23195 7d09f340909a023b79055781976113c7 353 TIGRFAM TIGR01927 menC_gamma/gm+: o-succinylbenzoate synthase 13 322 8.9E-41 T 29-03-2018 THSYN_RS23195 7d09f340909a023b79055781976113c7 353 Gene3D G3DSA:3.30.390.10 6 130 7.0E-17 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS17125 ac5d805cb469a734573d596934ac00cc 371 Gene3D G3DSA:1.10.10.10 6 65 4.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS17125 ac5d805cb469a734573d596934ac00cc 371 Pfam PF03781 Sulfatase-modifying factor enzyme 1 141 359 3.7E-52 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS17125 ac5d805cb469a734573d596934ac00cc 371 SUPERFAMILY SSF46689 4 65 1.04E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS17125 ac5d805cb469a734573d596934ac00cc 371 SUPERFAMILY SSF56436 141 360 5.89E-74 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS17125 ac5d805cb469a734573d596934ac00cc 371 Gene3D G3DSA:3.90.1580.10 132 206 3.8E-15 T 29-03-2018 THSYN_RS17125 ac5d805cb469a734573d596934ac00cc 371 Gene3D G3DSA:3.90.1580.10 207 369 2.3E-55 T 29-03-2018 THSYN_RS17125 ac5d805cb469a734573d596934ac00cc 371 Pfam PF04255 Protein of unknown function (DUF433) 6 61 2.5E-17 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS24140 eb29675d272e62429f57a49e27ed2ad0 358 Gene3D G3DSA:3.40.50.300 218 335 3.2E-8 T 29-03-2018 THSYN_RS24140 eb29675d272e62429f57a49e27ed2ad0 358 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 24 303 5.3E-21 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS24140 eb29675d272e62429f57a49e27ed2ad0 358 Gene3D G3DSA:3.40.50.300 1 180 2.6E-9 T 29-03-2018 THSYN_RS24140 eb29675d272e62429f57a49e27ed2ad0 358 SUPERFAMILY SSF52540 219 305 7.09E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24140 eb29675d272e62429f57a49e27ed2ad0 358 SUPERFAMILY SSF52540 1 158 7.09E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00455 1c5c72d67f22aa91581c3ac4864c0b08 107 Pfam PF12966 N-ATPase, AtpR subunit 6 86 5.2E-27 T 29-03-2018 IPR017581 N-ATPase, AtpR subunit-like THSYN_RS00455 1c5c72d67f22aa91581c3ac4864c0b08 107 TIGRFAM TIGR03165 F1F0_chp_2: F1/F0 ATPase, Methanosarcina type, subunit 2 6 86 1.5E-27 T 29-03-2018 IPR017581 N-ATPase, AtpR subunit-like THSYN_RS08290 604f8859dd27f6b944f8a22f0ad1c40e 386 PIRSF PIRSF031773 3 384 3.6E-63 T 29-03-2018 IPR005891 DevC protein THSYN_RS08290 604f8859dd27f6b944f8a22f0ad1c40e 386 Pfam PF02687 FtsX-like permease family 295 380 4.8E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THSYN_RS08290 604f8859dd27f6b944f8a22f0ad1c40e 386 Pfam PF12704 MacB-like periplasmic core domain 29 235 5.1E-11 T 29-03-2018 IPR025857 MacB-like periplasmic core domain THSYN_RS18255 d86b39efeea0d0b7c877a908a49f673c 472 Gene3D G3DSA:3.40.605.10 2 232 8.0E-51 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THSYN_RS18255 d86b39efeea0d0b7c877a908a49f673c 472 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 214 221 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THSYN_RS18255 d86b39efeea0d0b7c877a908a49f673c 472 Pfam PF00171 Aldehyde dehydrogenase family 24 437 1.8E-74 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THSYN_RS18255 d86b39efeea0d0b7c877a908a49f673c 472 SUPERFAMILY SSF53720 8 441 1.96E-101 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THSYN_RS18255 d86b39efeea0d0b7c877a908a49f673c 472 PIRSF PIRSF036492 1 471 6.8E-144 T 29-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 THSYN_RS18255 d86b39efeea0d0b7c877a908a49f673c 472 Gene3D G3DSA:3.40.309.10 233 424 4.7E-52 T 29-03-2018 THSYN_RS14200 6e2c4d9a21ee89067515dfb05be141ad 354 Gene3D G3DSA:1.10.3210.10 122 353 4.0E-48 T 29-03-2018 THSYN_RS14200 6e2c4d9a21ee89067515dfb05be141ad 354 SMART SM00471 171 308 6.9E-9 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS14200 6e2c4d9a21ee89067515dfb05be141ad 354 SUPERFAMILY SSF52172 10 162 1.57E-32 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS14200 6e2c4d9a21ee89067515dfb05be141ad 354 Pfam PF00072 Response regulator receiver domain 12 122 2.6E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS14200 6e2c4d9a21ee89067515dfb05be141ad 354 Pfam PF13487 HD domain 226 290 1.1E-17 T 29-03-2018 THSYN_RS14200 6e2c4d9a21ee89067515dfb05be141ad 354 SUPERFAMILY SSF109604 157 340 2.73E-35 T 29-03-2018 THSYN_RS14200 6e2c4d9a21ee89067515dfb05be141ad 354 SMART SM00448 10 122 4.8E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS14200 6e2c4d9a21ee89067515dfb05be141ad 354 Gene3D G3DSA:3.40.50.2300 3 121 8.1E-27 T 29-03-2018 THSYN_RS33205 54908d718aaf7708a633ec1bb9ae7469 464 Gene3D G3DSA:3.20.20.20 115 338 3.8E-9 T 29-03-2018 THSYN_RS33205 54908d718aaf7708a633ec1bb9ae7469 464 SUPERFAMILY SSF51717 114 329 7.72E-25 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS19975 ed5019b690e33dcc598ae4435e67dd1f 108 Gene3D G3DSA:3.40.30.10 18 98 2.7E-16 T 29-03-2018 THSYN_RS19975 ed5019b690e33dcc598ae4435e67dd1f 108 SMART SM01248 22 103 1.0E-49 T 29-03-2018 IPR011649 KaiB domain GO:0048511 THSYN_RS19975 ed5019b690e33dcc598ae4435e67dd1f 108 Pfam PF07689 KaiB domain 22 102 2.7E-26 T 29-03-2018 IPR011649 KaiB domain GO:0048511 THSYN_RS19975 ed5019b690e33dcc598ae4435e67dd1f 108 SUPERFAMILY SSF52833 10 104 9.79E-29 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS21240 714f8da292655c88bc1907fb79fe0457 375 Gene3D G3DSA:3.90.550.10 19 322 3.9E-48 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS21240 714f8da292655c88bc1907fb79fe0457 375 Pfam PF00535 Glycosyl transferase family 2 46 171 3.0E-25 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS21240 714f8da292655c88bc1907fb79fe0457 375 SUPERFAMILY SSF53448 43 290 1.5E-49 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS07645 06b4f731eacd210d821138dd6badb9b9 142 SMART SM00562 3 139 1.5E-82 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THSYN_RS07645 06b4f731eacd210d821138dd6badb9b9 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 4.3E-38 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THSYN_RS07645 06b4f731eacd210d821138dd6badb9b9 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 4.3E-38 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THSYN_RS07645 06b4f731eacd210d821138dd6badb9b9 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 4.3E-38 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THSYN_RS07645 06b4f731eacd210d821138dd6badb9b9 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 4.3E-38 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THSYN_RS07645 06b4f731eacd210d821138dd6badb9b9 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 4.3E-38 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THSYN_RS07645 06b4f731eacd210d821138dd6badb9b9 142 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 29-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THSYN_RS07645 06b4f731eacd210d821138dd6badb9b9 142 Pfam PF00334 Nucleoside diphosphate kinase 4 135 7.7E-55 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THSYN_RS07645 06b4f731eacd210d821138dd6badb9b9 142 SUPERFAMILY SSF54919 1 136 6.94E-57 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THSYN_RS07645 06b4f731eacd210d821138dd6badb9b9 142 Gene3D G3DSA:3.30.70.141 56 137 3.6E-33 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THSYN_RS07645 06b4f731eacd210d821138dd6badb9b9 142 Gene3D G3DSA:3.30.70.141 1 55 1.0E-17 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THSYN_RS07645 06b4f731eacd210d821138dd6badb9b9 142 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 141 34.285 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THSYN_RS27275 af0ae5c1282da3d62dfd2995c86e2bae 227 Gene3D G3DSA:1.25.40.20 135 226 5.1E-22 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS27275 af0ae5c1282da3d62dfd2995c86e2bae 227 SMART SM00248 131 158 2000.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS27275 af0ae5c1282da3d62dfd2995c86e2bae 227 SMART SM00248 162 191 1.2E-6 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS27275 af0ae5c1282da3d62dfd2995c86e2bae 227 SMART SM00248 99 128 0.65 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS27275 af0ae5c1282da3d62dfd2995c86e2bae 227 SMART SM00248 66 95 5.1E-4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS27275 af0ae5c1282da3d62dfd2995c86e2bae 227 Gene3D G3DSA:1.25.40.20 31 134 3.9E-24 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS27275 af0ae5c1282da3d62dfd2995c86e2bae 227 SUPERFAMILY SSF48403 38 206 6.38E-42 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS27275 af0ae5c1282da3d62dfd2995c86e2bae 227 Pfam PF12796 Ankyrin repeats (3 copies) 38 126 4.4E-12 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS27275 af0ae5c1282da3d62dfd2995c86e2bae 227 Pfam PF13857 Ankyrin repeats (many copies) 149 203 1.1E-11 T 29-03-2018 THSYN_RS27275 af0ae5c1282da3d62dfd2995c86e2bae 227 PRINTS PR01415 Ankyrin repeat signature 178 192 1.3E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS27275 af0ae5c1282da3d62dfd2995c86e2bae 227 PRINTS PR01415 Ankyrin repeat signature 67 82 1.3E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS25390 8d8fbd26a171494d04d2530c94bfd822 107 Pfam PF01909 Nucleotidyltransferase domain 21 83 2.7E-10 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS25390 8d8fbd26a171494d04d2530c94bfd822 107 SUPERFAMILY SSF81301 5 105 1.15E-17 T 29-03-2018 THSYN_RS25390 8d8fbd26a171494d04d2530c94bfd822 107 Gene3D G3DSA:3.30.460.10 2 107 2.1E-16 T 29-03-2018 THSYN_RS30100 68479328a37b1932cc5d74eac54f1dad 226 SUPERFAMILY SSF56719 5 210 2.62E-38 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THSYN_RS30100 68479328a37b1932cc5d74eac54f1dad 226 PRINTS PR00418 DNA topoisomerase II family signature 104 121 5.4E-17 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS30100 68479328a37b1932cc5d74eac54f1dad 226 PRINTS PR00418 DNA topoisomerase II family signature 174 190 5.4E-17 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS30100 68479328a37b1932cc5d74eac54f1dad 226 PRINTS PR00418 DNA topoisomerase II family signature 86 102 5.4E-17 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS30100 68479328a37b1932cc5d74eac54f1dad 226 PRINTS PR00418 DNA topoisomerase II family signature 124 136 5.4E-17 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS30100 68479328a37b1932cc5d74eac54f1dad 226 PRINTS PR00418 DNA topoisomerase II family signature 20 34 5.4E-17 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS30100 68479328a37b1932cc5d74eac54f1dad 226 Gene3D G3DSA:3.40.50.670 3 217 1.0E-43 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS30100 68479328a37b1932cc5d74eac54f1dad 226 Pfam PF01751 Toprim domain 19 129 2.6E-13 T 29-03-2018 IPR006171 TOPRIM domain THSYN_RS30100 68479328a37b1932cc5d74eac54f1dad 226 ProSitePatterns PS00177 DNA topoisomerase II signature. 22 30 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS12825 76928943efd2efefc6c3e8b91807633a 93 Pfam PF08681 Protein of unknown function (DUF1778) 10 88 3.6E-24 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 THSYN_RS12825 76928943efd2efefc6c3e8b91807633a 93 Gene3D G3DSA:1.20.890.30 54 89 6.6E-11 T 29-03-2018 THSYN_RS12825 76928943efd2efefc6c3e8b91807633a 93 Gene3D G3DSA:1.10.1220.10 7 50 4.0E-13 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS12825 76928943efd2efefc6c3e8b91807633a 93 SUPERFAMILY SSF47598 7 84 2.78E-20 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS22985 d24cba472568e3475350a8a0c6834261 118 Gene3D G3DSA:1.10.10.10 18 84 2.2E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS22985 d24cba472568e3475350a8a0c6834261 118 SUPERFAMILY SSF46785 6 112 1.2E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS22985 d24cba472568e3475350a8a0c6834261 118 Gene3D G3DSA:1.10.10.10 85 113 3.3E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 SUPERFAMILY SSF51621 168 339 1.64E-93 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 SUPERFAMILY SSF51621 2 76 1.64E-93 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 Gene3D G3DSA:3.20.20.60 169 321 1.6E-57 T 29-03-2018 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 Gene3D G3DSA:2.40.33.10 80 168 1.8E-21 T 29-03-2018 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 SUPERFAMILY SSF52935 324 472 1.7E-35 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 PRINTS PR01050 Pyruvate kinase family signature 217 243 3.8E-58 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 PRINTS PR01050 Pyruvate kinase family signature 60 76 3.8E-58 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 PRINTS PR01050 Pyruvate kinase family signature 294 312 3.8E-58 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 PRINTS PR01050 Pyruvate kinase family signature 244 268 3.8E-58 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 PRINTS PR01050 Pyruvate kinase family signature 269 293 3.8E-58 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 PRINTS PR01050 Pyruvate kinase family signature 313 329 3.8E-58 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 PRINTS PR01050 Pyruvate kinase family signature 187 201 3.8E-58 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 Gene3D G3DSA:3.20.20.60 1 79 6.7E-16 T 29-03-2018 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 SUPERFAMILY SSF50800 71 166 4.19E-22 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 469 5.5E-31 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 Gene3D G3DSA:3.40.1380.20 322 472 1.3E-39 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 471 5.3E-156 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS04885 e5f0e33cc6aa0fc00f803c36ce573ea1 480 Pfam PF00224 Pyruvate kinase, barrel domain 3 341 1.7E-115 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THSYN_RS22820 31699cbfc523b3fecc24d8f5500a8c91 239 Gene3D G3DSA:3.30.70.20 149 207 8.4E-4 T 29-03-2018 THSYN_RS22820 31699cbfc523b3fecc24d8f5500a8c91 239 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 82 117 3.4E-13 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS22820 31699cbfc523b3fecc24d8f5500a8c91 239 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 73 3.6E-17 T 29-03-2018 THSYN_RS22820 31699cbfc523b3fecc24d8f5500a8c91 239 SUPERFAMILY SSF54292 4 117 5.38E-29 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS22820 31699cbfc523b3fecc24d8f5500a8c91 239 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 97 109 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS22820 31699cbfc523b3fecc24d8f5500a8c91 239 PIRSF PIRSF000309 1 232 1.5E-73 T 29-03-2018 IPR016214 NAD-reducing hydrogenase, HoxS gamma subunit MetaCyc: PWY-5382|MetaCyc: PWY-6758 THSYN_RS22820 31699cbfc523b3fecc24d8f5500a8c91 239 Pfam PF13459 4Fe-4S single cluster domain 140 204 2.9E-10 T 29-03-2018 THSYN_RS22820 31699cbfc523b3fecc24d8f5500a8c91 239 Gene3D G3DSA:3.10.20.30 2 148 7.1E-16 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS22820 31699cbfc523b3fecc24d8f5500a8c91 239 SUPERFAMILY SSF54862 75 208 4.81E-27 T 29-03-2018 THSYN_RS22820 31699cbfc523b3fecc24d8f5500a8c91 239 SMART SM00929 82 122 1.1E-14 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS04145 b3bceacd42db2652624487357ec6f797 366 Pfam PF01594 AI-2E family transporter 22 347 4.1E-32 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like THSYN_RS07960 11a2a5004fc3e149248d8850b1934205 130 SUPERFAMILY SSF141734 4 111 7.45E-47 T 29-03-2018 THSYN_RS07960 11a2a5004fc3e149248d8850b1934205 130 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 5 109 31.696 T 29-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 THSYN_RS07960 11a2a5004fc3e149248d8850b1934205 130 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 31 105 9.4E-34 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 THSYN_RS07960 11a2a5004fc3e149248d8850b1934205 130 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 54 108 2.0E-19 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 THSYN_RS19355 2ec702110b7687afdb21a03615582c86 328 SMART SM00471 146 283 2.3E-11 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS19355 2ec702110b7687afdb21a03615582c86 328 SMART SM00448 4 116 2.1E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS19355 2ec702110b7687afdb21a03615582c86 328 SUPERFAMILY SSF109604 139 314 6.52E-42 T 29-03-2018 THSYN_RS19355 2ec702110b7687afdb21a03615582c86 328 Gene3D G3DSA:1.10.3210.10 116 323 3.3E-50 T 29-03-2018 THSYN_RS19355 2ec702110b7687afdb21a03615582c86 328 SUPERFAMILY SSF52172 5 124 1.57E-32 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS19355 2ec702110b7687afdb21a03615582c86 328 Pfam PF00072 Response regulator receiver domain 7 115 7.9E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS19355 2ec702110b7687afdb21a03615582c86 328 Gene3D G3DSA:3.40.50.2300 4 115 1.7E-26 T 29-03-2018 THSYN_RS19355 2ec702110b7687afdb21a03615582c86 328 Pfam PF01966 HD domain 152 273 1.2E-21 T 29-03-2018 IPR006674 HD domain THSYN_RS25900 9e0c20eccfcfcdab45bdc9496cc78f28 340 Gene3D G3DSA:1.10.1040.10 65 332 2.1E-121 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THSYN_RS25900 9e0c20eccfcfcdab45bdc9496cc78f28 340 PIRSF PIRSF000116 203 335 7.4E-14 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THSYN_RS25900 9e0c20eccfcfcdab45bdc9496cc78f28 340 PIRSF PIRSF000116 6 207 7.0E-45 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THSYN_RS25900 9e0c20eccfcfcdab45bdc9496cc78f28 340 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 328 3.2E-139 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THSYN_RS25900 9e0c20eccfcfcdab45bdc9496cc78f28 340 SUPERFAMILY SSF51735 4 184 6.78E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS25900 9e0c20eccfcfcdab45bdc9496cc78f28 340 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 3 330 45.82 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THSYN_RS25900 9e0c20eccfcfcdab45bdc9496cc78f28 340 SUPERFAMILY SSF48179 185 334 3.74E-71 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THSYN_RS25900 9e0c20eccfcfcdab45bdc9496cc78f28 340 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 328 1.9E-67 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THSYN_RS25900 9e0c20eccfcfcdab45bdc9496cc78f28 340 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 179 2.0E-74 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THSYN_RS21315 021c214579a79f577392539a9efc0408 638 PIRSF PIRSF001589 1 634 3.1E-172 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS21315 021c214579a79f577392539a9efc0408 638 Pfam PF00733 Asparagine synthase 244 627 1.7E-96 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THSYN_RS21315 021c214579a79f577392539a9efc0408 638 SUPERFAMILY SSF52402 482 622 3.14E-82 T 29-03-2018 THSYN_RS21315 021c214579a79f577392539a9efc0408 638 SUPERFAMILY SSF52402 234 383 3.14E-82 T 29-03-2018 THSYN_RS21315 021c214579a79f577392539a9efc0408 638 Pfam PF13537 Glutamine amidotransferase domain 48 166 3.0E-49 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain THSYN_RS21315 021c214579a79f577392539a9efc0408 638 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 562 2.4E-145 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS21315 021c214579a79f577392539a9efc0408 638 Gene3D G3DSA:3.60.20.10 1 224 1.0E-55 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS21315 021c214579a79f577392539a9efc0408 638 TIGRFAM TIGR03108 eps_aminotran_1: exosortase A system-associated amidotransferase 1 1 628 0.0 T 29-03-2018 IPR017539 Exosortase 1 system-associated amidotransferase 1 THSYN_RS21315 021c214579a79f577392539a9efc0408 638 Gene3D G3DSA:3.40.50.620 225 630 1.1E-70 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS21315 021c214579a79f577392539a9efc0408 638 SUPERFAMILY SSF56235 1 225 2.23E-64 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS25475 5ae62cf75106677a3130ba9c9748869f 176 TIGRFAM TIGR01955 RfaH: transcription elongation factor/antiterminator RfaH 4 161 4.9E-46 T 29-03-2018 IPR010215 Transcription antitermination protein RfaH GO:0006355 THSYN_RS25475 5ae62cf75106677a3130ba9c9748869f 176 Pfam PF02357 Transcription termination factor nusG 2 96 3.9E-15 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THSYN_RS25475 5ae62cf75106677a3130ba9c9748869f 176 Gene3D G3DSA:3.30.70.940 1 99 1.0E-14 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THSYN_RS25475 5ae62cf75106677a3130ba9c9748869f 176 SMART SM00738 1 100 1.6E-11 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THSYN_RS25475 5ae62cf75106677a3130ba9c9748869f 176 Gene3D G3DSA:2.30.30.30 112 164 1.8E-7 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 THSYN_RS25475 5ae62cf75106677a3130ba9c9748869f 176 SUPERFAMILY SSF50104 113 163 1.13E-7 T 29-03-2018 IPR008991 Translation protein SH3-like domain THSYN_RS25475 5ae62cf75106677a3130ba9c9748869f 176 SUPERFAMILY SSF82679 1 101 9.02E-23 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THSYN_RS27610 97fcb17857165dad00b626dd2c1854a7 297 SUPERFAMILY SSF52980 6 167 2.63E-30 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS27610 97fcb17857165dad00b626dd2c1854a7 297 Pfam PF05685 Putative restriction endonuclease 43 155 5.2E-17 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS27610 97fcb17857165dad00b626dd2c1854a7 297 Gene3D G3DSA:3.90.1570.10 18 176 7.5E-23 T 29-03-2018 THSYN_RS06665 573cd3f983a56e46ae692f6f8f1fbc70 839 ProSitePatterns PS00523 Sulfatases signature 1. 123 135 - T 29-03-2018 IPR024607 Sulfatase, conserved site THSYN_RS06665 573cd3f983a56e46ae692f6f8f1fbc70 839 Gene3D G3DSA:2.60.120.200 648 819 1.2E-5 T 29-03-2018 THSYN_RS06665 573cd3f983a56e46ae692f6f8f1fbc70 839 Pfam PF00884 Sulfatase 79 497 3.5E-67 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THSYN_RS06665 573cd3f983a56e46ae692f6f8f1fbc70 839 Gene3D G3DSA:3.40.720.10 76 527 3.5E-81 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS06665 573cd3f983a56e46ae692f6f8f1fbc70 839 Gene3D G3DSA:3.30.1120.10 528 626 6.7E-15 T 29-03-2018 THSYN_RS06665 573cd3f983a56e46ae692f6f8f1fbc70 839 SUPERFAMILY SSF53649 79 615 7.56E-113 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS21780 dc2c16a3fe6093c1538f5d2109297447 87 SUPERFAMILY SSF54862 4 64 1.82E-9 T 29-03-2018 THSYN_RS21780 dc2c16a3fe6093c1538f5d2109297447 87 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 12 23 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS21780 dc2c16a3fe6093c1538f5d2109297447 87 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 9.6E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 THSYN_RS21780 dc2c16a3fe6093c1538f5d2109297447 87 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 9.6E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 THSYN_RS21780 dc2c16a3fe6093c1538f5d2109297447 87 PRINTS PR00352 3Fe-4S ferredoxin signature 49 61 9.6E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 THSYN_RS21780 dc2c16a3fe6093c1538f5d2109297447 87 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 62 3.4E-11 T 29-03-2018 THSYN_RS21780 dc2c16a3fe6093c1538f5d2109297447 87 Gene3D G3DSA:3.30.70.20 21 80 2.9E-5 T 29-03-2018 THSYN_RS21780 dc2c16a3fe6093c1538f5d2109297447 87 Gene3D G3DSA:3.30.70.20 2 20 0.0011 T 29-03-2018 THSYN_RS25635 c715d12eb9f735b0628658d423829053 78 Pfam PF04325 Protein of unknown function (DUF465) 29 76 2.7E-14 T 29-03-2018 IPR007420 Protein of unknown function DUF465 THSYN_RS07210 e106cd7018f9d54e3fb1f08c65151436 617 SUPERFAMILY SSF52402 227 381 1.1E-71 T 29-03-2018 THSYN_RS07210 e106cd7018f9d54e3fb1f08c65151436 617 SUPERFAMILY SSF52402 458 577 1.1E-71 T 29-03-2018 THSYN_RS07210 e106cd7018f9d54e3fb1f08c65151436 617 Gene3D G3DSA:3.40.50.620 222 602 5.4E-63 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS07210 e106cd7018f9d54e3fb1f08c65151436 617 Gene3D G3DSA:3.60.20.10 1 221 1.9E-54 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS07210 e106cd7018f9d54e3fb1f08c65151436 617 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 538 2.4E-139 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS07210 e106cd7018f9d54e3fb1f08c65151436 617 Pfam PF13537 Glutamine amidotransferase domain 48 168 7.8E-46 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain THSYN_RS07210 e106cd7018f9d54e3fb1f08c65151436 617 Pfam PF00733 Asparagine synthase 240 586 4.6E-79 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THSYN_RS07210 e106cd7018f9d54e3fb1f08c65151436 617 SUPERFAMILY SSF56235 1 224 1.72E-65 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS07210 e106cd7018f9d54e3fb1f08c65151436 617 PIRSF PIRSF001589 1 613 8.5E-155 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS06355 9a9d5cf79a76cb4e81b4e2405cd90896 671 SUPERFAMILY SSF100950 18 278 3.89E-88 T 29-03-2018 THSYN_RS06355 9a9d5cf79a76cb4e81b4e2405cd90896 671 SMART SM00882 22 267 1.5E-66 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 THSYN_RS06355 9a9d5cf79a76cb4e81b4e2405cd90896 671 SMART SM00882 305 513 0.0011 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 THSYN_RS06355 9a9d5cf79a76cb4e81b4e2405cd90896 671 SUPERFAMILY SSF100950 301 541 8.38E-76 T 29-03-2018 THSYN_RS06355 9a9d5cf79a76cb4e81b4e2405cd90896 671 Gene3D G3DSA:3.40.1080.10 12 292 8.0E-87 T 29-03-2018 THSYN_RS06355 9a9d5cf79a76cb4e81b4e2405cd90896 671 Gene3D G3DSA:3.40.1080.10 299 546 2.0E-57 T 29-03-2018 THSYN_RS06355 9a9d5cf79a76cb4e81b4e2405cd90896 671 Pfam PF01144 Coenzyme A transferase 24 267 3.8E-33 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 THSYN_RS06280 5a99280476fc561f4f5ef29967ae6b0a 299 SUPERFAMILY SSF102114 5 225 5.89E-30 T 29-03-2018 THSYN_RS06280 5a99280476fc561f4f5ef29967ae6b0a 299 SMART SM00729 21 241 3.1E-21 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS06280 5a99280476fc561f4f5ef29967ae6b0a 299 Gene3D G3DSA:3.20.20.70 15 278 5.8E-27 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS06280 5a99280476fc561f4f5ef29967ae6b0a 299 Pfam PF04055 Radical SAM superfamily 26 196 4.7E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS05920 8b8ec40ee824619a08f3c3df4627ebcd 373 Gene3D G3DSA:3.40.50.2000 176 372 1.6E-41 T 29-03-2018 THSYN_RS05920 8b8ec40ee824619a08f3c3df4627ebcd 373 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 91 346 5.0E-34 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 THSYN_RS05920 8b8ec40ee824619a08f3c3df4627ebcd 373 SUPERFAMILY SSF53756 14 370 4.55E-81 T 29-03-2018 THSYN_RS05920 8b8ec40ee824619a08f3c3df4627ebcd 373 Gene3D G3DSA:3.40.50.2000 10 174 3.7E-41 T 29-03-2018 THSYN_RS22115 2bfb8b4ff354b7cb389ed8e06ed6cd14 137 Pfam PF01934 Protein of unknown function DUF86 21 130 2.9E-24 T 29-03-2018 IPR008201 Protein of unknown function DUF86 THSYN_RS22115 2bfb8b4ff354b7cb389ed8e06ed6cd14 137 Gene3D G3DSA:1.20.120.580 1 136 1.2E-23 T 29-03-2018 IPR008201 Protein of unknown function DUF86 THSYN_RS29515 63e4a52a1de27000083a23c9b4557481 855 Hamap MF_01871 UPF0753 protein . 37 847 23.66 T 29-03-2018 IPR018752 Uncharacterised protein family UPF0753 THSYN_RS29515 63e4a52a1de27000083a23c9b4557481 855 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 42 832 1.2E-263 T 29-03-2018 IPR018752 Uncharacterised protein family UPF0753 THSYN_RS30390 60b41f1065dd1ee6b5e2c8ba3b5563fb 482 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 30 267 2.5E-39 T 29-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system THSYN_RS30390 60b41f1065dd1ee6b5e2c8ba3b5563fb 482 Pfam PF13280 WYL domain 314 384 1.2E-8 T 29-03-2018 IPR026881 WYL domain THSYN_RS18185 6e6c924b811ac790d7620e00190b5a96 441 Gene3D G3DSA:1.10.287.470 151 199 1.9E-12 T 29-03-2018 THSYN_RS18185 6e6c924b811ac790d7620e00190b5a96 441 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 82 306 1.7E-16 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS18185 6e6c924b811ac790d7620e00190b5a96 441 Gene3D G3DSA:2.40.50.100 94 150 2.1E-17 T 29-03-2018 THSYN_RS18185 6e6c924b811ac790d7620e00190b5a96 441 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 70 390 2.0E-74 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS18185 6e6c924b811ac790d7620e00190b5a96 441 Gene3D G3DSA:2.40.50.100 200 389 0.0022 T 29-03-2018 THSYN_RS18185 6e6c924b811ac790d7620e00190b5a96 441 SUPERFAMILY SSF111369 83 309 5.49E-25 T 29-03-2018 THSYN_RS18210 985fe878cdf9e811c2082567a32a4a02 292 Gene3D G3DSA:2.60.40.10 195 288 9.8E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS18210 985fe878cdf9e811c2082567a32a4a02 292 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 120 127 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site THSYN_RS18210 985fe878cdf9e811c2082567a32a4a02 292 PRINTS PR00107 Phosphocarrier protein signature 160 177 3.1E-11 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS18210 985fe878cdf9e811c2082567a32a4a02 292 PRINTS PR00107 Phosphocarrier protein signature 145 160 3.1E-11 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS18210 985fe878cdf9e811c2082567a32a4a02 292 PRINTS PR00107 Phosphocarrier protein signature 120 136 3.1E-11 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS18210 985fe878cdf9e811c2082567a32a4a02 292 Pfam PF00381 PTS HPr component phosphorylation site 112 189 1.4E-22 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS18210 985fe878cdf9e811c2082567a32a4a02 292 SUPERFAMILY SSF49452 203 272 1.52E-5 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 THSYN_RS18210 985fe878cdf9e811c2082567a32a4a02 292 SUPERFAMILY SSF55594 111 195 1.7E-23 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS18210 985fe878cdf9e811c2082567a32a4a02 292 Gene3D G3DSA:3.30.1340.10 106 189 1.1E-23 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS18210 985fe878cdf9e811c2082567a32a4a02 292 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 112 188 7.7E-22 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS22605 b8945bb4a34ff28f597e7fe6eb1cae4d 492 Pfam PF01943 Polysaccharide biosynthesis protein 10 287 1.8E-10 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 THSYN_RS22605 b8945bb4a34ff28f597e7fe6eb1cae4d 492 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 352 480 3.7E-9 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain THSYN_RS31275 41d820e68e85b3265fc87d2307371189 385 SUPERFAMILY SSF46785 56 137 9.26E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS31275 41d820e68e85b3265fc87d2307371189 385 Pfam PF00891 O-methyltransferase 143 368 2.3E-44 T 29-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 THSYN_RS31275 41d820e68e85b3265fc87d2307371189 385 SUPERFAMILY SSF53335 142 376 6.33E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS31275 41d820e68e85b3265fc87d2307371189 385 Pfam PF16864 Dimerisation domain 58 125 9.9E-13 T 29-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain THSYN_RS31275 41d820e68e85b3265fc87d2307371189 385 Gene3D G3DSA:3.40.50.150 142 377 3.7E-29 T 29-03-2018 THSYN_RS31275 41d820e68e85b3265fc87d2307371189 385 Gene3D G3DSA:1.10.10.10 50 138 9.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS31275 41d820e68e85b3265fc87d2307371189 385 PIRSF PIRSF005739 50 381 5.8E-22 T 29-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 THSYN_RS30325 3c34b8addabe77c82dff5387ac0e3e6d 406 SUPERFAMILY SSF56954 2 404 1.83E-33 T 29-03-2018 THSYN_RS30325 3c34b8addabe77c82dff5387ac0e3e6d 406 Pfam PF02321 Outer membrane efflux protein 231 402 1.2E-9 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THSYN_RS30325 3c34b8addabe77c82dff5387ac0e3e6d 406 Pfam PF02321 Outer membrane efflux protein 32 202 1.5E-5 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THSYN_RS30325 3c34b8addabe77c82dff5387ac0e3e6d 406 Gene3D G3DSA:1.20.1600.10 8 404 6.6E-30 T 29-03-2018 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 PIRSF PIRSF000381 1 851 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 SUPERFAMILY SSF51717 11 285 3.27E-91 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 Gene3D G3DSA:3.10.196.10 739 883 1.6E-59 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 Pfam PF00809 Pterin binding enzyme 15 253 5.0E-59 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 593 864 9.6E-121 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 Gene3D G3DSA:1.10.288.10 668 738 2.0E-18 T 29-03-2018 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 SUPERFAMILY SSF56507 556 882 2.09E-129 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 Gene3D G3DSA:1.10.1240.10 300 387 2.1E-36 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 SUPERFAMILY SSF52242 398 547 1.44E-43 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 Gene3D G3DSA:3.40.50.280 388 558 5.3E-54 T 29-03-2018 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 SMART SM01018 311 394 8.4E-43 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 Gene3D G3DSA:1.10.288.10 593 649 5.9E-26 T 29-03-2018 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 TIGRFAM TIGR02082 metH: methionine synthase 6 848 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 Pfam PF02310 B12 binding domain 402 496 1.3E-18 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 SUPERFAMILY SSF47644 306 393 6.54E-28 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 Pfam PF02607 B12 binding domain 313 387 3.2E-24 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS08605 4a34fbcdf55f5fdc2a12fa17d701a054 883 Gene3D G3DSA:3.20.20.20 1 299 8.7E-74 T 29-03-2018 THSYN_RS03430 adc5cc53f49f86ccb90eaa835e27062c 437 SUPERFAMILY SSF52540 289 375 2.53E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03430 adc5cc53f49f86ccb90eaa835e27062c 437 SUPERFAMILY SSF52540 1 104 2.53E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03430 adc5cc53f49f86ccb90eaa835e27062c 437 PIRSF PIRSF029347 181 406 5.0E-18 T 29-03-2018 IPR014555 RecF-like THSYN_RS03430 adc5cc53f49f86ccb90eaa835e27062c 437 PIRSF PIRSF029347 1 94 1.1E-9 T 29-03-2018 IPR014555 RecF-like THSYN_RS03430 adc5cc53f49f86ccb90eaa835e27062c 437 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 23 90 2.3E-6 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS03430 adc5cc53f49f86ccb90eaa835e27062c 437 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 286 371 3.2E-22 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS03430 adc5cc53f49f86ccb90eaa835e27062c 437 Gene3D G3DSA:3.40.50.300 1 377 7.7E-21 T 29-03-2018 THSYN_RS26115 79891cb7a9c07636cdc756b3395a16aa 137 Pfam PF01475 Ferric uptake regulator family 9 128 1.4E-43 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 THSYN_RS26115 79891cb7a9c07636cdc756b3395a16aa 137 SUPERFAMILY SSF46785 4 132 2.29E-43 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26115 79891cb7a9c07636cdc756b3395a16aa 137 Gene3D G3DSA:1.10.10.10 2 88 2.3E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS01425 0f0889281ffc61d89ab13a6bcd1537fc 188 Gene3D G3DSA:3.90.870.10 6 187 6.6E-50 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain THSYN_RS01425 0f0889281ffc61d89ab13a6bcd1537fc 188 Pfam PF01300 Telomere recombination 16 187 1.6E-37 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 THSYN_RS01425 0f0889281ffc61d89ab13a6bcd1537fc 188 SUPERFAMILY SSF55821 9 187 1.53E-49 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain THSYN_RS01425 0f0889281ffc61d89ab13a6bcd1537fc 188 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 7 187 35.806 T 29-03-2018 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 THSYN_RS03825 49738bf7e567f9fdb5da22157048cce3 178 Pfam PF05981 CreA protein 22 153 4.0E-53 T 29-03-2018 IPR010292 Uncharacterised protein family CreA THSYN_RS03825 49738bf7e567f9fdb5da22157048cce3 178 PIRSF PIRSF003174 1 161 3.7E-59 T 29-03-2018 IPR010292 Uncharacterised protein family CreA THSYN_RS09170 77a33a0bddc7c67efc41648106c74c5c 185 SUPERFAMILY SSF56235 3 177 6.51E-59 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS09170 77a33a0bddc7c67efc41648106c74c5c 185 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 177 42.263 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 THSYN_RS09170 77a33a0bddc7c67efc41648106c74c5c 185 Pfam PF00227 Proteasome subunit 4 174 7.2E-23 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 THSYN_RS09170 77a33a0bddc7c67efc41648106c74c5c 185 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 177 1.5E-86 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 THSYN_RS09170 77a33a0bddc7c67efc41648106c74c5c 185 Gene3D G3DSA:3.60.20.10 7 179 1.1E-31 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS09170 77a33a0bddc7c67efc41648106c74c5c 185 PIRSF PIRSF039093 1 180 1.1E-88 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 THSYN_RS23570 ddad9b0a163789ed7665d165babd4c8a 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 161 188 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS23570 ddad9b0a163789ed7665d165babd4c8a 208 SUPERFAMILY SSF52172 2 131 9.25E-24 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS23570 ddad9b0a163789ed7665d165babd4c8a 208 Gene3D G3DSA:1.10.10.10 128 208 1.5E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS23570 ddad9b0a163789ed7665d165babd4c8a 208 Gene3D G3DSA:3.40.50.2300 2 127 3.8E-25 T 29-03-2018 THSYN_RS23570 ddad9b0a163789ed7665d165babd4c8a 208 SMART SM00421 144 201 1.9E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS23570 ddad9b0a163789ed7665d165babd4c8a 208 SUPERFAMILY SSF46894 130 206 2.45E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS23570 ddad9b0a163789ed7665d165babd4c8a 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 201 2.9E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS23570 ddad9b0a163789ed7665d165babd4c8a 208 SMART SM00448 3 116 2.9E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS23570 ddad9b0a163789ed7665d165babd4c8a 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 6.0E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS23570 ddad9b0a163789ed7665d165babd4c8a 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 6.0E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS23570 ddad9b0a163789ed7665d165babd4c8a 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 6.0E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS23570 ddad9b0a163789ed7665d165babd4c8a 208 Pfam PF00072 Response regulator receiver domain 5 116 2.1E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS05485 eab51dd221999c558858bfa2793c19f5 352 SUPERFAMILY SSF56925 35 205 4.45E-15 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THSYN_RS05485 eab51dd221999c558858bfa2793c19f5 352 PRINTS PR01021 OMPA domain signature 235 257 7.9E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS05485 eab51dd221999c558858bfa2793c19f5 352 PRINTS PR01021 OMPA domain signature 265 280 7.9E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS05485 eab51dd221999c558858bfa2793c19f5 352 PRINTS PR01021 OMPA domain signature 280 296 7.9E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS05485 eab51dd221999c558858bfa2793c19f5 352 Gene3D G3DSA:3.30.1330.60 227 352 2.4E-29 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS05485 eab51dd221999c558858bfa2793c19f5 352 Pfam PF00691 OmpA family 234 326 6.0E-18 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS05485 eab51dd221999c558858bfa2793c19f5 352 Pfam PF13505 Outer membrane protein beta-barrel domain 14 194 6.9E-10 T 29-03-2018 IPR027385 Outer membrane protein beta-barrel THSYN_RS05485 eab51dd221999c558858bfa2793c19f5 352 Gene3D G3DSA:2.40.160.20 10 226 2.7E-17 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THSYN_RS05485 eab51dd221999c558858bfa2793c19f5 352 SUPERFAMILY SSF103088 223 345 7.32E-29 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS28180 68d29c078fa6631fbc0ace49a0c3c99d 327 Pfam PF13424 Tetratricopeptide repeat 163 225 4.1E-9 T 29-03-2018 THSYN_RS28180 68d29c078fa6631fbc0ace49a0c3c99d 327 Gene3D G3DSA:3.30.70.100 160 201 8.6E-15 T 29-03-2018 THSYN_RS28180 68d29c078fa6631fbc0ace49a0c3c99d 327 Gene3D G3DSA:3.30.70.100 242 272 9.8E-6 T 29-03-2018 THSYN_RS28180 68d29c078fa6631fbc0ace49a0c3c99d 327 Gene3D G3DSA:3.30.70.100 202 241 4.3E-10 T 29-03-2018 THSYN_RS28180 68d29c078fa6631fbc0ace49a0c3c99d 327 Gene3D G3DSA:3.30.70.100 98 159 4.0E-11 T 29-03-2018 THSYN_RS28180 68d29c078fa6631fbc0ace49a0c3c99d 327 Pfam PF13176 Tetratricopeptide repeat 123 155 6.2E-7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS28180 68d29c078fa6631fbc0ace49a0c3c99d 327 SMART SM00028 120 153 0.035 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS28180 68d29c078fa6631fbc0ace49a0c3c99d 327 SMART SM00028 238 271 230.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS28180 68d29c078fa6631fbc0ace49a0c3c99d 327 SMART SM00028 278 311 28.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS28180 68d29c078fa6631fbc0ace49a0c3c99d 327 SMART SM00028 198 231 1.3 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS28180 68d29c078fa6631fbc0ace49a0c3c99d 327 SMART SM00028 158 191 3.1E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS28180 68d29c078fa6631fbc0ace49a0c3c99d 327 Gene3D G3DSA:1.10.150.200 273 325 1.7E-4 T 29-03-2018 THSYN_RS28180 68d29c078fa6631fbc0ace49a0c3c99d 327 SUPERFAMILY SSF48452 121 308 1.39E-31 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS06480 ba74dc2b74d50d51fb6fde29cfcf25aa 410 Gene3D G3DSA:1.10.8.60 335 405 4.3E-7 T 29-03-2018 THSYN_RS06480 ba74dc2b74d50d51fb6fde29cfcf25aa 410 SUPERFAMILY SSF52540 150 398 1.2E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06480 ba74dc2b74d50d51fb6fde29cfcf25aa 410 Gene3D G3DSA:3.40.50.300 144 334 1.5E-29 T 29-03-2018 THSYN_RS06480 ba74dc2b74d50d51fb6fde29cfcf25aa 410 SMART SM00382 196 330 2.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS06480 ba74dc2b74d50d51fb6fde29cfcf25aa 410 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 326 4.5E-25 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS27405 370084be834acaf19ba0451e2e0d9fb6 164 Pfam PF13091 PLD-like domain 15 108 1.8E-9 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THSYN_RS27405 370084be834acaf19ba0451e2e0d9fb6 164 SUPERFAMILY SSF56024 9 109 6.73E-15 T 29-03-2018 THSYN_RS27405 370084be834acaf19ba0451e2e0d9fb6 164 Gene3D G3DSA:3.30.870.10 2 109 1.3E-12 T 29-03-2018 THSYN_RS00385 aae0431252340df189ed4235ea99e990 630 Gene3D G3DSA:2.30.38.10 413 493 5.3E-13 T 29-03-2018 THSYN_RS00385 aae0431252340df189ed4235ea99e990 630 ProSitePatterns PS00455 Putative AMP-binding domain signature. 235 246 - T 29-03-2018 IPR020845 AMP-binding, conserved site THSYN_RS00385 aae0431252340df189ed4235ea99e990 630 Gene3D G3DSA:3.30.300.30 494 603 7.3E-23 T 29-03-2018 THSYN_RS00385 aae0431252340df189ed4235ea99e990 630 Gene3D G3DSA:3.40.50.980 49 240 1.0E-47 T 29-03-2018 THSYN_RS00385 aae0431252340df189ed4235ea99e990 630 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 3 57 6.5E-22 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 THSYN_RS00385 aae0431252340df189ed4235ea99e990 630 Pfam PF00501 AMP-binding enzyme 59 499 1.1E-87 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THSYN_RS00385 aae0431252340df189ed4235ea99e990 630 Gene3D G3DSA:3.40.50.980 241 402 3.2E-36 T 29-03-2018 THSYN_RS00385 aae0431252340df189ed4235ea99e990 630 SUPERFAMILY SSF56801 3 621 8.24E-161 T 29-03-2018 THSYN_RS00385 aae0431252340df189ed4235ea99e990 630 Pfam PF13193 AMP-binding enzyme C-terminal domain 509 587 2.3E-24 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain THSYN_RS05050 fe15bdf984e92c1bc166171a3cdbd966 140 Gene3D G3DSA:3.40.50.1010 1 140 1.2E-14 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS05050 fe15bdf984e92c1bc166171a3cdbd966 140 Pfam PF13470 PIN domain 2 114 5.5E-18 T 29-03-2018 IPR002716 PIN domain THSYN_RS05050 fe15bdf984e92c1bc166171a3cdbd966 140 SUPERFAMILY SSF88723 1 120 9.53E-12 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS05050 fe15bdf984e92c1bc166171a3cdbd966 140 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 2 111 1.3E-9 T 29-03-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component THSYN_RS23140 6352aa32e8f80045177604ed62ee5e04 286 SUPERFAMILY SSF53335 42 224 1.7E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS23140 6352aa32e8f80045177604ed62ee5e04 286 Gene3D G3DSA:3.40.50.150 17 210 5.5E-24 T 29-03-2018 THSYN_RS23140 6352aa32e8f80045177604ed62ee5e04 286 Pfam PF13489 Methyltransferase domain 63 203 4.0E-16 T 29-03-2018 THSYN_RS22370 7b95203db2e2db06bda6ad8d98584169 110 SUPERFAMILY SSF46689 16 79 6.09E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS22370 7b95203db2e2db06bda6ad8d98584169 110 Pfam PF04255 Protein of unknown function (DUF433) 16 66 1.6E-9 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS22370 7b95203db2e2db06bda6ad8d98584169 110 Gene3D G3DSA:1.10.10.10 13 74 2.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS04915 2d62898d867d07fb8f890c0fa9d899e6 116 Gene3D G3DSA:1.10.10.10 15 73 5.4E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS04915 2d62898d867d07fb8f890c0fa9d899e6 116 SUPERFAMILY SSF47413 42 112 7.7E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS04915 2d62898d867d07fb8f890c0fa9d899e6 116 Gene3D G3DSA:3.30.1190.10 74 116 2.8E-6 T 29-03-2018 THSYN_RS04915 2d62898d867d07fb8f890c0fa9d899e6 116 SMART SM00530 55 111 3.5E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS04915 2d62898d867d07fb8f890c0fa9d899e6 116 Pfam PF13744 Helix-turn-helix domain 37 112 1.0E-21 T 29-03-2018 THSYN_RS00485 afb265d15ecbfdbc46eee5fd15f337fd 304 PRINTS PR00126 ATP synthase gamma subunit signature 80 99 1.5E-15 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00485 afb265d15ecbfdbc46eee5fd15f337fd 304 PRINTS PR00126 ATP synthase gamma subunit signature 272 293 1.5E-15 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00485 afb265d15ecbfdbc46eee5fd15f337fd 304 PRINTS PR00126 ATP synthase gamma subunit signature 241 260 1.5E-15 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00485 afb265d15ecbfdbc46eee5fd15f337fd 304 SUPERFAMILY SSF52943 6 294 3.14E-49 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00485 afb265d15ecbfdbc46eee5fd15f337fd 304 TIGRFAM TIGR03323 alt_F1F0_F1_gam: alternate F1F0 ATPase, F1 subunit gamma 8 294 6.6E-121 T 29-03-2018 IPR017709 Alternate ATP synthase, F1 complex, subunit gamma THSYN_RS00485 afb265d15ecbfdbc46eee5fd15f337fd 304 Gene3D G3DSA:3.40.1380.10 73 181 3.9E-17 T 29-03-2018 THSYN_RS00485 afb265d15ecbfdbc46eee5fd15f337fd 304 Pfam PF00231 ATP synthase 6 294 1.0E-53 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00485 afb265d15ecbfdbc46eee5fd15f337fd 304 Gene3D G3DSA:1.10.287.80 182 248 1.1E-11 T 29-03-2018 THSYN_RS00485 afb265d15ecbfdbc46eee5fd15f337fd 304 Gene3D G3DSA:1.10.287.80 4 72 0.62 T 29-03-2018 THSYN_RS00485 afb265d15ecbfdbc46eee5fd15f337fd 304 Gene3D G3DSA:1.10.287.80 249 289 1.7E-5 T 29-03-2018 THSYN_RS16555 fee33aed5ad603c698c7462b76642083 430 Pfam PF16114 ATP citrate lyase citrate-binding 258 401 1.4E-18 T 29-03-2018 IPR032263 ATP-citrate synthase, citrate-binding domain KEGG: 00020+2.3.3.8|KEGG: 00720+2.3.3.8|MetaCyc: PWY-5172|Reactome: R-HSA-163765|Reactome: R-HSA-6798695|Reactome: R-HSA-75105 THSYN_RS16555 fee33aed5ad603c698c7462b76642083 430 Pfam PF08442 ATP-grasp domain 53 197 3.7E-13 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THSYN_RS16555 fee33aed5ad603c698c7462b76642083 430 SUPERFAMILY SSF56059 9 221 1.41E-24 T 29-03-2018 THSYN_RS16555 fee33aed5ad603c698c7462b76642083 430 Gene3D G3DSA:3.30.470.20 88 222 1.1E-20 T 29-03-2018 THSYN_RS17320 cb76a7a46d68b34eb41d6ab0e03ae386 1101 Pfam PF13809 Tubulin like 18 363 2.4E-44 T 29-03-2018 IPR025904 Tubulin-like THSYN_RS17320 cb76a7a46d68b34eb41d6ab0e03ae386 1101 Gene3D G3DSA:3.40.50.1440 14 235 1.6E-11 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS17320 cb76a7a46d68b34eb41d6ab0e03ae386 1101 Gene3D G3DSA:3.50.50.60 329 1059 0.022 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS15435 1844871a8cd3c8271ad498da6204366d 630 Pfam PF17482 Phage tail sheath C-terminal domain 516 621 2.6E-13 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain THSYN_RS15435 1844871a8cd3c8271ad498da6204366d 630 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 350 515 4.5E-23 T 29-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain THSYN_RS25950 a9107bdde96bcde4a8d3460b70e6993f 289 Gene3D G3DSA:3.60.21.10 19 277 1.6E-34 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS25950 a9107bdde96bcde4a8d3460b70e6993f 289 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 31 275 38.265 T 29-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 THSYN_RS25950 a9107bdde96bcde4a8d3460b70e6993f 289 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 220 275 3.0E-10 T 29-03-2018 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 THSYN_RS25950 a9107bdde96bcde4a8d3460b70e6993f 289 Pfam PF00149 Calcineurin-like phosphoesterase 31 220 2.7E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS25950 a9107bdde96bcde4a8d3460b70e6993f 289 SUPERFAMILY SSF56300 31 281 1.04E-52 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS09830 cd943368d4a2d5c971fa1b1dd46b7ebb 323 SMART SM00267 121 317 1.1E-63 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS09830 cd943368d4a2d5c971fa1b1dd46b7ebb 323 Gene3D G3DSA:3.30.70.270 130 322 3.4E-54 T 29-03-2018 THSYN_RS09830 cd943368d4a2d5c971fa1b1dd46b7ebb 323 Pfam PF00990 Diguanylate cyclase, GGDEF domain 133 264 2.4E-43 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS09830 cd943368d4a2d5c971fa1b1dd46b7ebb 323 SUPERFAMILY SSF55073 137 317 6.47E-44 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS09830 cd943368d4a2d5c971fa1b1dd46b7ebb 323 SMART SM00448 5 115 8.4E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS09830 cd943368d4a2d5c971fa1b1dd46b7ebb 323 SUPERFAMILY SSF52172 4 133 3.84E-38 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS09830 cd943368d4a2d5c971fa1b1dd46b7ebb 323 Gene3D G3DSA:3.40.50.2300 4 129 7.7E-35 T 29-03-2018 THSYN_RS09830 cd943368d4a2d5c971fa1b1dd46b7ebb 323 Pfam PF00072 Response regulator receiver domain 7 115 1.6E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS09830 cd943368d4a2d5c971fa1b1dd46b7ebb 323 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 130 264 1.1E-40 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS08970 d05065a671dacb5afd4b9d820b02ccdb 291 ProSitePatterns PS00746 NifH/frxC family signature 1. 88 100 - T 29-03-2018 IPR030655 NifH/chlL conserved site THSYN_RS08970 d05065a671dacb5afd4b9d820b02ccdb 291 TIGRFAM TIGR01287 nifH: nitrogenase iron protein 4 278 7.3E-141 T 29-03-2018 IPR005977 Nitrogenase iron protein NifH GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 THSYN_RS08970 d05065a671dacb5afd4b9d820b02ccdb 291 PRINTS PR00091 Nitrogenase component II signature 125 140 8.4E-38 T 29-03-2018 THSYN_RS08970 d05065a671dacb5afd4b9d820b02ccdb 291 PRINTS PR00091 Nitrogenase component II signature 9 22 8.4E-38 T 29-03-2018 THSYN_RS08970 d05065a671dacb5afd4b9d820b02ccdb 291 PRINTS PR00091 Nitrogenase component II signature 31 46 8.4E-38 T 29-03-2018 THSYN_RS08970 d05065a671dacb5afd4b9d820b02ccdb 291 PRINTS PR00091 Nitrogenase component II signature 86 100 8.4E-38 T 29-03-2018 THSYN_RS08970 d05065a671dacb5afd4b9d820b02ccdb 291 ProSitePatterns PS00692 NifH/frxC family signature 2. 126 139 - T 29-03-2018 IPR030655 NifH/chlL conserved site THSYN_RS08970 d05065a671dacb5afd4b9d820b02ccdb 291 SUPERFAMILY SSF52540 7 275 4.71E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08970 d05065a671dacb5afd4b9d820b02ccdb 291 PIRSF PIRSF000363 2 278 3.0E-123 T 29-03-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 THSYN_RS08970 d05065a671dacb5afd4b9d820b02ccdb 291 Gene3D G3DSA:3.40.50.300 4 272 5.4E-44 T 29-03-2018 THSYN_RS08970 d05065a671dacb5afd4b9d820b02ccdb 291 Hamap MF_00533 Nitrogenase iron protein [nifH]. 3 276 51.59 T 29-03-2018 IPR005977 Nitrogenase iron protein NifH GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 THSYN_RS08970 d05065a671dacb5afd4b9d820b02ccdb 291 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 4 275 3.3E-137 T 29-03-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 THSYN_RS16890 76eb29ac402e50fa8d0d6b73596eecee 695 Pfam PF02378 Phosphotransferase system, EIIC 18 424 8.8E-76 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 THSYN_RS16890 76eb29ac402e50fa8d0d6b73596eecee 695 Pfam PF00367 phosphotransferase system, EIIB 620 651 1.1E-5 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 THSYN_RS16890 76eb29ac402e50fa8d0d6b73596eecee 695 Pfam PF00367 phosphotransferase system, EIIB 510 543 1.6E-11 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 THSYN_RS16890 76eb29ac402e50fa8d0d6b73596eecee 695 SUPERFAMILY SSF55604 619 692 3.14E-10 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 THSYN_RS16890 76eb29ac402e50fa8d0d6b73596eecee 695 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 483 567 3.3E-18 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 THSYN_RS16890 76eb29ac402e50fa8d0d6b73596eecee 695 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 521 538 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 THSYN_RS16890 76eb29ac402e50fa8d0d6b73596eecee 695 Gene3D G3DSA:3.30.1360.60 617 693 1.0E-16 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 THSYN_RS16890 76eb29ac402e50fa8d0d6b73596eecee 695 Gene3D G3DSA:3.30.1360.60 506 581 1.3E-24 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 THSYN_RS16890 76eb29ac402e50fa8d0d6b73596eecee 695 SUPERFAMILY SSF55604 508 581 1.31E-19 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 THSYN_RS11820 bef2322e7a508a6eee0d7eb55d851cc3 194 Gene3D G3DSA:3.30.1890.10 74 169 2.2E-5 T 29-03-2018 THSYN_RS11820 bef2322e7a508a6eee0d7eb55d851cc3 194 Pfam PF02706 Chain length determinant protein 49 143 7.4E-9 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 THSYN_RS18065 88c7021c8c4465e783c14c96759f7acc 553 Gene3D G3DSA:1.10.10.10 493 548 3.1E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS18065 88c7021c8c4465e783c14c96759f7acc 553 SUPERFAMILY SSF46785 496 543 4.57E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS18065 88c7021c8c4465e783c14c96759f7acc 553 Gene3D G3DSA:1.10.10.60 151 180 0.046 T 29-03-2018 THSYN_RS18065 88c7021c8c4465e783c14c96759f7acc 553 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 301 383 1.1E-13 T 29-03-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain THSYN_RS18065 88c7021c8c4465e783c14c96759f7acc 553 Gene3D G3DSA:1.10.10.10 332 492 0.0032 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS18065 88c7021c8c4465e783c14c96759f7acc 553 Pfam PF06224 Winged helix DNA-binding domain 416 539 2.6E-6 T 29-03-2018 IPR009351 Protein of unknown function DUF1006 THSYN_RS18065 88c7021c8c4465e783c14c96759f7acc 553 Pfam PF04326 Putative DNA-binding domain 10 104 3.3E-12 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 THSYN_RS09525 847660e1d229c5467863223f7f5efda4 308 Pfam PF07728 AAA domain (dynein-related subfamily) 45 213 7.4E-11 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THSYN_RS09525 847660e1d229c5467863223f7f5efda4 308 Gene3D G3DSA:3.40.50.300 26 258 5.7E-22 T 29-03-2018 THSYN_RS09525 847660e1d229c5467863223f7f5efda4 308 SUPERFAMILY SSF52540 142 275 4.02E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09525 847660e1d229c5467863223f7f5efda4 308 SUPERFAMILY SSF52540 33 93 4.02E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09525 847660e1d229c5467863223f7f5efda4 308 SMART SM00382 41 221 9.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS19700 5100688b9d2342672bfbe134606ba162 147 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 140 2.2E-23 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 THSYN_RS19700 5100688b9d2342672bfbe134606ba162 147 TIGRFAM TIGR02801 tolR: protein TolR 14 139 2.1E-40 T 29-03-2018 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 THSYN_RS23845 d01af89d2f8ff3aef923d8c9eaee2a97 131 Gene3D G3DSA:3.30.1490.10 75 130 1.6E-17 T 29-03-2018 THSYN_RS23845 d01af89d2f8ff3aef923d8c9eaee2a97 131 Pfam PF00410 Ribosomal protein S8 5 130 3.8E-43 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23845 d01af89d2f8ff3aef923d8c9eaee2a97 131 SUPERFAMILY SSF56047 2 130 1.7E-44 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23845 d01af89d2f8ff3aef923d8c9eaee2a97 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23845 d01af89d2f8ff3aef923d8c9eaee2a97 131 Gene3D G3DSA:3.30.1370.30 2 73 1.5E-24 T 29-03-2018 THSYN_RS23845 d01af89d2f8ff3aef923d8c9eaee2a97 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 29.616 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS09385 0b70f9716dbc78ee73139de1087ea0c7 215 SUPERFAMILY SSF52266 27 206 3.21E-48 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain THSYN_RS09385 0b70f9716dbc78ee73139de1087ea0c7 215 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 32 191 5.7E-23 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain THSYN_RS09385 0b70f9716dbc78ee73139de1087ea0c7 215 Gene3D G3DSA:3.40.50.1110 27 209 5.1E-36 T 29-03-2018 THSYN_RS05795 833adb95461fdd8892d03be8f9b01928 251 Gene3D G3DSA:1.20.58.220 14 129 1.9E-21 T 29-03-2018 THSYN_RS05795 833adb95461fdd8892d03be8f9b01928 251 SUPERFAMILY SSF109755 20 237 4.4E-36 T 29-03-2018 THSYN_RS05795 833adb95461fdd8892d03be8f9b01928 251 Pfam PF01895 PhoU domain 33 120 3.5E-14 T 29-03-2018 IPR026022 PhoU domain THSYN_RS05795 833adb95461fdd8892d03be8f9b01928 251 Gene3D G3DSA:1.20.58.220 132 248 3.1E-7 T 29-03-2018 THSYN_RS05990 8001410bd945e6888c558f84afd35198 161 SUPERFAMILY SSF47188 64 148 1.31E-20 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 THSYN_RS05990 8001410bd945e6888c558f84afd35198 161 SUPERFAMILY SSF47188 3 33 1.31E-20 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 THSYN_RS05990 8001410bd945e6888c558f84afd35198 161 Gene3D G3DSA:1.20.120.50 1 152 2.1E-23 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 THSYN_RS05450 708e0a03a0531a4ac953be0f135cd83c 563 SUPERFAMILY SSF111369 129 315 1.18E-10 T 29-03-2018 THSYN_RS05450 708e0a03a0531a4ac953be0f135cd83c 563 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 216 389 4.4E-33 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS05450 708e0a03a0531a4ac953be0f135cd83c 563 Pfam PF11827 Protein of unknown function (DUF3347) 489 560 3.6E-13 T 29-03-2018 IPR021782 Protein of unknown function DUF3347 THSYN_RS05450 708e0a03a0531a4ac953be0f135cd83c 563 Gene3D G3DSA:2.40.50.100 214 525 2.9E-10 T 29-03-2018 THSYN_RS05450 708e0a03a0531a4ac953be0f135cd83c 563 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 108 315 1.5E-59 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS05450 708e0a03a0531a4ac953be0f135cd83c 563 Gene3D G3DSA:2.40.50.100 124 200 1.8E-4 T 29-03-2018 THSYN_RS18055 3c96c433d32168fbcc83e29646fe156a 108 Gene3D G3DSA:1.20.1440.60 1 107 5.9E-29 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS18055 3c96c433d32168fbcc83e29646fe156a 108 SUPERFAMILY SSF158446 1 103 1.31E-30 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS18055 3c96c433d32168fbcc83e29646fe156a 108 Pfam PF05635 23S rRNA-intervening sequence protein 1 96 4.8E-30 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS18055 3c96c433d32168fbcc83e29646fe156a 108 TIGRFAM TIGR02436 TIGR02436: four helix bundle protein 1 101 3.3E-31 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS22235 d42f271784824ba8a7f04b3667b3ed45 422 SUPERFAMILY SSF63867 342 419 6.28E-12 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THSYN_RS22235 d42f271784824ba8a7f04b3667b3ed45 422 Gene3D G3DSA:3.40.980.10 165 339 5.4E-54 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS22235 d42f271784824ba8a7f04b3667b3ed45 422 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 268 301 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 THSYN_RS22235 d42f271784824ba8a7f04b3667b3ed45 422 Pfam PF03454 MoeA C-terminal region (domain IV) 346 417 4.9E-8 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THSYN_RS22235 d42f271784824ba8a7f04b3667b3ed45 422 Gene3D G3DSA:2.40.340.10 345 413 1.8E-11 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THSYN_RS22235 d42f271784824ba8a7f04b3667b3ed45 422 Pfam PF00994 Probable molybdopterin binding domain 195 330 2.0E-22 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS22235 d42f271784824ba8a7f04b3667b3ed45 422 SMART SM00852 195 332 1.7E-38 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS22235 d42f271784824ba8a7f04b3667b3ed45 422 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 192 328 2.4E-27 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS22235 d42f271784824ba8a7f04b3667b3ed45 422 Gene3D G3DSA:2.170.190.11 76 156 8.8E-27 T 29-03-2018 THSYN_RS22235 d42f271784824ba8a7f04b3667b3ed45 422 Gene3D G3DSA:3.90.105.10 40 75 3.5E-11 T 29-03-2018 THSYN_RS22235 d42f271784824ba8a7f04b3667b3ed45 422 SUPERFAMILY SSF63882 20 190 6.93E-53 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THSYN_RS22235 d42f271784824ba8a7f04b3667b3ed45 422 SUPERFAMILY SSF53218 192 337 2.62E-41 T 29-03-2018 IPR001453 MoaB/Mog domain THSYN_RS22235 d42f271784824ba8a7f04b3667b3ed45 422 Pfam PF03453 MoeA N-terminal region (domain I and II) 24 182 1.1E-44 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THSYN_RS00305 71f173b2c9d8230e2b63b59311ba5a58 526 SUPERFAMILY SSF56935 75 526 1.16E-106 T 29-03-2018 THSYN_RS00305 71f173b2c9d8230e2b63b59311ba5a58 526 Pfam PF02264 LamB porin 76 526 4.6E-114 T 29-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 THSYN_RS00305 71f173b2c9d8230e2b63b59311ba5a58 526 Gene3D G3DSA:2.40.170.10 75 526 4.4E-124 T 29-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 THSYN_RS00305 71f173b2c9d8230e2b63b59311ba5a58 526 ProDom PD008788 PORIN MEMBRANE PRECURSOR SIGNAL MALTOPORIN OUTER ION TRANSMEMBRANE RECEPTOR LAMB 81 497 2.0E-84 T 29-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 THSYN_RS14075 6306703070218aa856693264a2874df4 474 SUPERFAMILY SSF55785 147 278 6.98E-15 T 29-03-2018 IPR000014 PAS domain THSYN_RS14075 6306703070218aa856693264a2874df4 474 SUPERFAMILY SSF55073 317 468 4.71E-48 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS14075 6306703070218aa856693264a2874df4 474 SUPERFAMILY SSF55785 18 148 6.14E-23 T 29-03-2018 IPR000014 PAS domain THSYN_RS14075 6306703070218aa856693264a2874df4 474 Gene3D G3DSA:3.30.70.270 306 470 2.9E-56 T 29-03-2018 THSYN_RS14075 6306703070218aa856693264a2874df4 474 Gene3D G3DSA:3.30.450.20 156 305 1.5E-26 T 29-03-2018 THSYN_RS14075 6306703070218aa856693264a2874df4 474 SMART SM00267 301 469 5.9E-67 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS14075 6306703070218aa856693264a2874df4 474 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 28 156 9.5E-19 T 29-03-2018 IPR000014 PAS domain THSYN_RS14075 6306703070218aa856693264a2874df4 474 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 158 287 3.4E-8 T 29-03-2018 IPR000014 PAS domain THSYN_RS14075 6306703070218aa856693264a2874df4 474 Pfam PF00989 PAS fold 163 259 7.0E-5 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS14075 6306703070218aa856693264a2874df4 474 Pfam PF00989 PAS fold 33 147 1.3E-12 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS14075 6306703070218aa856693264a2874df4 474 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 308 468 3.0E-50 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS14075 6306703070218aa856693264a2874df4 474 Gene3D G3DSA:3.30.450.20 12 155 4.8E-30 T 29-03-2018 THSYN_RS14075 6306703070218aa856693264a2874df4 474 SMART SM00086 244 280 0.74 T 29-03-2018 IPR001610 PAC motif THSYN_RS14075 6306703070218aa856693264a2874df4 474 SMART SM00086 108 150 5.1E-9 T 29-03-2018 IPR001610 PAC motif THSYN_RS14075 6306703070218aa856693264a2874df4 474 SMART SM00091 30 96 8.0E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS14075 6306703070218aa856693264a2874df4 474 SMART SM00091 162 233 1.9E-4 T 29-03-2018 IPR000014 PAS domain THSYN_RS14075 6306703070218aa856693264a2874df4 474 Pfam PF00990 Diguanylate cyclase, GGDEF domain 312 465 2.5E-48 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS18200 efde6fff3adacb69f45d201758e17d57 327 Pfam PF04754 Putative transposase, YhgA-like 3 203 1.5E-28 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS18200 efde6fff3adacb69f45d201758e17d57 327 Pfam PF14261 Domain of unknown function (DUF4351) 268 321 5.2E-7 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS20955 2f5cda577d8f54f9996eea8f2500f2bf 802 Gene3D G3DSA:1.20.5.50 624 799 0.0041 T 29-03-2018 THSYN_RS20955 2f5cda577d8f54f9996eea8f2500f2bf 802 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 158 174 2.9E-16 T 29-03-2018 THSYN_RS20955 2f5cda577d8f54f9996eea8f2500f2bf 802 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 258 270 2.9E-16 T 29-03-2018 THSYN_RS20955 2f5cda577d8f54f9996eea8f2500f2bf 802 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 187 201 2.9E-16 T 29-03-2018 THSYN_RS20955 2f5cda577d8f54f9996eea8f2500f2bf 802 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 296 320 2.9E-16 T 29-03-2018 THSYN_RS20955 2f5cda577d8f54f9996eea8f2500f2bf 802 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 96 449 1.6E-72 T 29-03-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 THSYN_RS20955 2f5cda577d8f54f9996eea8f2500f2bf 802 Pfam PF12161 HsdM N-terminal domain 8 94 1.5E-11 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS20955 2f5cda577d8f54f9996eea8f2500f2bf 802 SUPERFAMILY SSF53335 6 484 1.27E-114 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS20955 2f5cda577d8f54f9996eea8f2500f2bf 802 Pfam PF02384 N-6 DNA Methylase 135 444 1.3E-92 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS20955 2f5cda577d8f54f9996eea8f2500f2bf 802 Gene3D G3DSA:3.40.50.150 156 439 1.2E-53 T 29-03-2018 THSYN_RS19385 c32ef9b043a6208c7e7aa5e26716b5f5 767 SUPERFAMILY SSF52540 328 582 5.6E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19385 c32ef9b043a6208c7e7aa5e26716b5f5 767 SUPERFAMILY SSF52540 250 299 5.6E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19385 c32ef9b043a6208c7e7aa5e26716b5f5 767 Gene3D G3DSA:3.40.50.300 450 609 1.7E-9 T 29-03-2018 THSYN_RS19385 c32ef9b043a6208c7e7aa5e26716b5f5 767 Gene3D G3DSA:1.10.3210.10 6 211 3.0E-4 T 29-03-2018 THSYN_RS19385 c32ef9b043a6208c7e7aa5e26716b5f5 767 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 20 182 6.4E-16 T 29-03-2018 IPR006483 CRISPR-associated Cas3-HD domain THSYN_RS19385 c32ef9b043a6208c7e7aa5e26716b5f5 767 SMART SM00487 218 438 0.002 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS19385 c32ef9b043a6208c7e7aa5e26716b5f5 767 Gene3D G3DSA:3.40.50.300 212 438 2.7E-18 T 29-03-2018 THSYN_RS19385 c32ef9b043a6208c7e7aa5e26716b5f5 767 Pfam PF00270 DEAD/DEAH box helicase 251 420 4.9E-9 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS17285 4607c5b6c1658467c0a18602f934e1bb 552 Gene3D G3DSA:3.40.50.300 287 518 1.8E-9 T 29-03-2018 THSYN_RS17285 4607c5b6c1658467c0a18602f934e1bb 552 SUPERFAMILY SSF52540 353 471 4.13E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17285 4607c5b6c1658467c0a18602f934e1bb 552 SUPERFAMILY SSF52540 290 325 4.13E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15180 1633a8475399ff42958de8799e914c15 312 SUPERFAMILY SSF52151 5 181 3.4E-48 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS15180 1633a8475399ff42958de8799e914c15 312 Pfam PF01734 Patatin-like phospholipase 9 167 5.6E-21 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 THSYN_RS15180 1633a8475399ff42958de8799e914c15 312 Gene3D G3DSA:3.40.1090.10 1 218 1.3E-36 T 29-03-2018 THSYN_RS23285 896e5755fecf9dc85ca85b75d4cb8ff1 229 Pfam PF05990 Alpha/beta hydrolase of unknown function (DUF900) 72 149 1.6E-13 T 29-03-2018 IPR010297 Protein of unknown function DUF900, hydrolase-like THSYN_RS27800 a301989effd87d929380b0a87dee6f9f 320 Gene3D G3DSA:3.40.50.720 3 139 1.4E-32 T 29-03-2018 THSYN_RS27800 a301989effd87d929380b0a87dee6f9f 320 SUPERFAMILY SSF55347 159 298 8.07E-15 T 29-03-2018 THSYN_RS27800 a301989effd87d929380b0a87dee6f9f 320 Gene3D G3DSA:3.30.360.10 140 318 5.9E-26 T 29-03-2018 THSYN_RS27800 a301989effd87d929380b0a87dee6f9f 320 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 14 130 4.0E-27 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 THSYN_RS27800 a301989effd87d929380b0a87dee6f9f 320 SUPERFAMILY SSF51735 10 149 1.57E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS03600 2979426971aa8005a82ee54fb5ec939d 306 SUPERFAMILY SSF51261 74 288 1.41E-57 T 29-03-2018 IPR011055 Duplicated hybrid motif THSYN_RS03600 2979426971aa8005a82ee54fb5ec939d 306 Pfam PF01551 Peptidase family M23 191 285 5.3E-35 T 29-03-2018 IPR016047 Peptidase M23 THSYN_RS03600 2979426971aa8005a82ee54fb5ec939d 306 Gene3D G3DSA:2.70.70.10 115 294 1.2E-47 T 29-03-2018 THSYN_RS12925 02322a798caffb39f805db94814bda4c 74 Pfam PF09722 Protein of unknown function (DUF2384) 21 71 1.3E-17 T 29-03-2018 IPR024467 Domain of unknown function DUF2384 THSYN_RS12925 02322a798caffb39f805db94814bda4c 74 TIGRFAM TIGR02293 TAS_TIGR02293: putative toxin-antitoxin system antitoxin component, TIGR02293 family 2 73 2.4E-20 T 29-03-2018 IPR011979 Conserved hypothetical protein CHP02293 THSYN_RS18350 7238c4882ba43594366cb8b803b704e5 361 Pfam PF01594 AI-2E family transporter 14 327 2.4E-52 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like THSYN_RS11070 a763b397d88630f0dde799a78f6b804e 222 Gene3D G3DSA:3.40.50.1460 76 219 8.5E-19 T 29-03-2018 THSYN_RS11070 a763b397d88630f0dde799a78f6b804e 222 SUPERFAMILY SSF52129 81 180 4.19E-16 T 29-03-2018 IPR029030 Caspase-like domain THSYN_RS11070 a763b397d88630f0dde799a78f6b804e 222 Gene3D G3DSA:3.40.50.1460 3 75 0.02 T 29-03-2018 THSYN_RS11070 a763b397d88630f0dde799a78f6b804e 222 Pfam PF00656 Caspase domain 92 189 1.8E-11 T 29-03-2018 THSYN_RS10830 9b0337268cd34188007a2ced83781516 426 SUPERFAMILY SSF52540 57 392 1.01E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10830 9b0337268cd34188007a2ced83781516 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 2 405 4.4E-142 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 THSYN_RS10830 9b0337268cd34188007a2ced83781516 426 SMART SM01086 317 411 4.0E-29 T 29-03-2018 IPR019489 Clp ATPase, C-terminal THSYN_RS10830 9b0337268cd34188007a2ced83781516 426 Gene3D G3DSA:3.40.50.300 52 315 3.1E-59 T 29-03-2018 THSYN_RS10830 9b0337268cd34188007a2ced83781516 426 SMART SM00382 112 267 1.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS10830 9b0337268cd34188007a2ced83781516 426 Pfam PF06689 ClpX C4-type zinc finger 7 41 6.3E-11 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 THSYN_RS10830 9b0337268cd34188007a2ced83781516 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 391 5.9E-14 T 29-03-2018 IPR019489 Clp ATPase, C-terminal THSYN_RS10830 9b0337268cd34188007a2ced83781516 426 SMART SM00994 5 44 1.3E-12 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 THSYN_RS10830 9b0337268cd34188007a2ced83781516 426 Gene3D G3DSA:1.10.8.60 317 407 2.8E-29 T 29-03-2018 THSYN_RS10830 9b0337268cd34188007a2ced83781516 426 SUPERFAMILY SSF57716 7 41 5.42E-7 T 29-03-2018 THSYN_RS10830 9b0337268cd34188007a2ced83781516 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 310 2.0E-40 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS05955 b8a251afba052c68cfb4a7c31113e4a4 310 Pfam PF04321 RmlD substrate binding domain 18 306 1.9E-99 T 29-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 THSYN_RS05955 b8a251afba052c68cfb4a7c31113e4a4 310 Gene3D G3DSA:3.90.25.10 225 295 4.0E-25 T 29-03-2018 THSYN_RS05955 b8a251afba052c68cfb4a7c31113e4a4 310 Gene3D G3DSA:3.40.50.720 10 189 3.8E-20 T 29-03-2018 THSYN_RS05955 b8a251afba052c68cfb4a7c31113e4a4 310 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 18 306 1.5E-95 T 29-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 THSYN_RS05955 b8a251afba052c68cfb4a7c31113e4a4 310 Gene3D G3DSA:3.90.25.10 190 224 9.7E-6 T 29-03-2018 THSYN_RS05955 b8a251afba052c68cfb4a7c31113e4a4 310 SUPERFAMILY SSF51735 18 306 1.35E-94 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS15765 15f784a3d5cbee9b3ac752edd6677e13 723 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 721 0.0 T 29-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 THSYN_RS15765 15f784a3d5cbee9b3ac752edd6677e13 723 Hamap MF_00641 Malate synthase G [glcB]. 1 723 386.733 T 29-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 THSYN_RS15765 15f784a3d5cbee9b3ac752edd6677e13 723 Gene3D G3DSA:1.10.1860.10 1 88 5.7E-32 T 29-03-2018 THSYN_RS15765 15f784a3d5cbee9b3ac752edd6677e13 723 SUPERFAMILY SSF51645 2 721 9.02E-295 T 29-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 THSYN_RS15765 15f784a3d5cbee9b3ac752edd6677e13 723 Pfam PF01274 Malate synthase 18 686 1.1E-158 T 29-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 THSYN_RS15765 15f784a3d5cbee9b3ac752edd6677e13 723 Gene3D G3DSA:3.20.20.360 89 215 9.8E-20 T 29-03-2018 THSYN_RS15765 15f784a3d5cbee9b3ac752edd6677e13 723 Gene3D G3DSA:3.20.20.360 220 589 5.1E-102 T 29-03-2018 THSYN_RS15765 15f784a3d5cbee9b3ac752edd6677e13 723 Gene3D G3DSA:1.20.1220.12 590 723 1.1E-39 T 29-03-2018 THSYN_RS28710 dc2f684d9c60f4f50d4050e36e0d1fd1 689 SMART SM00609 37 161 2.3E-7 T 29-03-2018 IPR013694 VIT domain THSYN_RS28710 dc2f684d9c60f4f50d4050e36e0d1fd1 689 Pfam PF08487 Vault protein inter-alpha-trypsin domain 49 159 1.3E-28 T 29-03-2018 IPR013694 VIT domain THSYN_RS28710 dc2f684d9c60f4f50d4050e36e0d1fd1 689 SUPERFAMILY SSF53300 315 477 3.86E-22 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS28710 dc2f684d9c60f4f50d4050e36e0d1fd1 689 Gene3D G3DSA:3.40.50.410 288 484 3.0E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS28710 dc2f684d9c60f4f50d4050e36e0d1fd1 689 Pfam PF13768 von Willebrand factor type A domain 318 464 6.4E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS28710 dc2f684d9c60f4f50d4050e36e0d1fd1 689 SMART SM00327 314 482 1.2E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS33120 12fed7a564456d99bb77a8d6a08c3f63 347 Gene3D G3DSA:3.30.420.10 169 338 1.4E-12 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS33120 12fed7a564456d99bb77a8d6a08c3f63 347 SUPERFAMILY SSF46689 28 130 1.76E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS33120 12fed7a564456d99bb77a8d6a08c3f63 347 SUPERFAMILY SSF53098 206 304 6.64E-7 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS33120 12fed7a564456d99bb77a8d6a08c3f63 347 Pfam PF13358 DDE superfamily endonuclease 170 309 1.9E-24 T 29-03-2018 THSYN_RS23145 6e919fa4723a43a29f6d2e3b1da6b999 692 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 17 108 8.0E-10 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 THSYN_RS23145 6e919fa4723a43a29f6d2e3b1da6b999 692 SUPERFAMILY SSF81296 12 148 8.96E-24 T 29-03-2018 IPR014756 Immunoglobulin E-set THSYN_RS23145 6e919fa4723a43a29f6d2e3b1da6b999 692 SMART SM00642 135 569 3.5E-9 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THSYN_RS23145 6e919fa4723a43a29f6d2e3b1da6b999 692 Gene3D G3DSA:2.60.40.1180 582 692 3.3E-22 T 29-03-2018 THSYN_RS23145 6e919fa4723a43a29f6d2e3b1da6b999 692 Gene3D G3DSA:2.60.40.10 1 148 7.9E-20 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS23145 6e919fa4723a43a29f6d2e3b1da6b999 692 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 15 660 1.3E-198 T 29-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 THSYN_RS23145 6e919fa4723a43a29f6d2e3b1da6b999 692 Gene3D G3DSA:3.20.20.80 149 581 2.0E-115 T 29-03-2018 THSYN_RS23145 6e919fa4723a43a29f6d2e3b1da6b999 692 SUPERFAMILY SSF51011 590 689 4.03E-17 T 29-03-2018 THSYN_RS23145 6e919fa4723a43a29f6d2e3b1da6b999 692 Pfam PF00128 Alpha amylase, catalytic domain 178 274 6.4E-12 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THSYN_RS23145 6e919fa4723a43a29f6d2e3b1da6b999 692 SUPERFAMILY SSF51445 138 472 1.55E-130 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS23145 6e919fa4723a43a29f6d2e3b1da6b999 692 SUPERFAMILY SSF51445 501 576 1.55E-130 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS08010 ca3eda07c68de4c9f6d6707a01c7e6a0 434 SUPERFAMILY SSF53822 32 402 2.32E-86 T 29-03-2018 IPR028082 Periplasmic binding protein-like I THSYN_RS08010 ca3eda07c68de4c9f6d6707a01c7e6a0 434 Pfam PF13433 Periplasmic binding protein domain 33 401 1.3E-169 T 29-03-2018 THSYN_RS08010 ca3eda07c68de4c9f6d6707a01c7e6a0 434 Gene3D G3DSA:3.40.50.2300 18 163 1.0E-17 T 29-03-2018 THSYN_RS08010 ca3eda07c68de4c9f6d6707a01c7e6a0 434 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 33 398 4.7E-170 T 29-03-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like THSYN_RS08010 ca3eda07c68de4c9f6d6707a01c7e6a0 434 Gene3D G3DSA:3.40.50.2300 164 349 3.1E-25 T 29-03-2018 THSYN_RS24990 76997afe3295d70c3a67931e0afc541c 607 Pfam PF16889 Heparinase II/III N-terminus 157 290 1.7E-13 T 29-03-2018 IPR031680 Heparin-sulfate lyase, N-terminal MetaCyc: PWY-7651 THSYN_RS24990 76997afe3295d70c3a67931e0afc541c 607 Pfam PF07940 Heparinase II/III-like protein 351 591 4.4E-53 T 29-03-2018 IPR012480 Heparinase II/III-like GO:0016829 THSYN_RS24990 76997afe3295d70c3a67931e0afc541c 607 SUPERFAMILY SSF48230 75 249 7.78E-12 T 29-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 THSYN_RS24990 76997afe3295d70c3a67931e0afc541c 607 Gene3D G3DSA:1.50.10.100 108 310 7.3E-19 T 29-03-2018 THSYN_RS22030 d835f0071025fe9d917a24c7e8d386aa 240 Gene3D G3DSA:3.40.1160.10 2 238 1.4E-45 T 29-03-2018 THSYN_RS22030 d835f0071025fe9d917a24c7e8d386aa 240 PIRSF PIRSF005650 1 240 9.3E-84 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 THSYN_RS22030 d835f0071025fe9d917a24c7e8d386aa 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 236 1.2E-90 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 THSYN_RS22030 d835f0071025fe9d917a24c7e8d386aa 240 SUPERFAMILY SSF53633 4 237 1.31E-69 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase THSYN_RS22030 d835f0071025fe9d917a24c7e8d386aa 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 237 41.883 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 THSYN_RS22030 d835f0071025fe9d917a24c7e8d386aa 240 Pfam PF00696 Amino acid kinase family 8 216 3.8E-28 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase THSYN_RS22375 78b4d4221451456ab584eab629a1ed70 92 Gene3D G3DSA:3.40.1620.10 3 40 3.3E-12 T 29-03-2018 THSYN_RS22375 78b4d4221451456ab584eab629a1ed70 92 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 42 6.1E-8 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS22375 78b4d4221451456ab584eab629a1ed70 92 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 44 3.2E-9 T 29-03-2018 THSYN_RS22375 78b4d4221451456ab584eab629a1ed70 92 SUPERFAMILY SSF143120 4 45 1.44E-8 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS07680 27a4a9f02be351db6301b8de89528081 609 SUPERFAMILY SSF55486 189 424 6.3E-9 T 29-03-2018 THSYN_RS07680 27a4a9f02be351db6301b8de89528081 609 Pfam PF13180 PDZ domain 511 573 2.2E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS07680 27a4a9f02be351db6301b8de89528081 609 SUPERFAMILY SSF50156 510 577 1.58E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS07680 27a4a9f02be351db6301b8de89528081 609 Pfam PF05299 M61 glycyl aminopeptidase 278 393 3.6E-44 T 29-03-2018 IPR007963 Peptidase M61, catalytic domain THSYN_RS07680 27a4a9f02be351db6301b8de89528081 609 Gene3D G3DSA:1.10.390.10 267 458 9.1E-20 T 29-03-2018 THSYN_RS07680 27a4a9f02be351db6301b8de89528081 609 PIRSF PIRSF016493 1 606 9.0E-200 T 29-03-2018 IPR024191 Peptidase M61 THSYN_RS07680 27a4a9f02be351db6301b8de89528081 609 Gene3D G3DSA:2.30.42.10 469 586 5.7E-10 T 29-03-2018 THSYN_RS07680 27a4a9f02be351db6301b8de89528081 609 SMART SM00228 499 568 2.3E-5 T 29-03-2018 IPR001478 PDZ domain GO:0005515 THSYN_RS14935 c1613c81c69a8b81c4fb5d1812700996 221 Gene3D G3DSA:1.10.3470.10 1 101 9.0E-4 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like THSYN_RS00475 5d5571732b1079b7d9c2741d2d4cc7e7 534 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 12 473 4.0E-189 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00475 5d5571732b1079b7d9c2741d2d4cc7e7 534 TIGRFAM TIGR03324 alt_F1F0_F1_al: alternate F1F0 ATPase, F1 subunit alpha 6 500 1.7E-267 T 29-03-2018 IPR017710 Alternate ATP synthase, F1 complex, subunit alpha GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS00475 5d5571732b1079b7d9c2741d2d4cc7e7 534 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 153 368 1.1E-67 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS00475 5d5571732b1079b7d9c2741d2d4cc7e7 534 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 359 368 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS00475 5d5571732b1079b7d9c2741d2d4cc7e7 534 SUPERFAMILY SSF52540 99 374 2.0E-94 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00475 5d5571732b1079b7d9c2741d2d4cc7e7 534 SUPERFAMILY SSF50615 16 98 7.32E-21 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS00475 5d5571732b1079b7d9c2741d2d4cc7e7 534 SUPERFAMILY SSF47917 378 504 2.88E-27 T 29-03-2018 THSYN_RS00475 5d5571732b1079b7d9c2741d2d4cc7e7 534 Gene3D G3DSA:2.40.30.20 30 87 4.1E-21 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00475 5d5571732b1079b7d9c2741d2d4cc7e7 534 Gene3D G3DSA:1.20.150.20 377 504 4.5E-28 T 29-03-2018 THSYN_RS00475 5d5571732b1079b7d9c2741d2d4cc7e7 534 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 5 505 40.803 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00475 5d5571732b1079b7d9c2741d2d4cc7e7 534 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 375 494 2.0E-27 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00475 5d5571732b1079b7d9c2741d2d4cc7e7 534 Gene3D G3DSA:3.40.50.300 88 368 8.5E-104 T 29-03-2018 THSYN_RS20740 b7dc1817e2e46c851b16e9e3327279aa 95 Hamap MF_00634 UPF0235 protein YggU [yggU]. 6 94 18.386 T 29-03-2018 IPR003746 Protein of unknown function DUF167 THSYN_RS20740 b7dc1817e2e46c851b16e9e3327279aa 95 SMART SM01152 6 82 1.6E-29 T 29-03-2018 IPR003746 Protein of unknown function DUF167 THSYN_RS20740 b7dc1817e2e46c851b16e9e3327279aa 95 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 10 80 4.4E-24 T 29-03-2018 IPR003746 Protein of unknown function DUF167 THSYN_RS20740 b7dc1817e2e46c851b16e9e3327279aa 95 SUPERFAMILY SSF69786 2 85 8.37E-25 T 29-03-2018 IPR003746 Protein of unknown function DUF167 THSYN_RS20740 b7dc1817e2e46c851b16e9e3327279aa 95 Gene3D G3DSA:3.30.1200.10 1 91 2.6E-25 T 29-03-2018 IPR003746 Protein of unknown function DUF167 THSYN_RS20415 6e16910f15a54808a95ff1e06b8d3520 1194 Gene3D G3DSA:3.40.50.300 53 342 5.8E-5 T 29-03-2018 THSYN_RS28405 d717be706a7f7e3a382d8d6095715559 383 SUPERFAMILY SSF48452 254 354 4.55E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS28405 d717be706a7f7e3a382d8d6095715559 383 Gene3D G3DSA:1.25.40.120 238 364 1.7E-10 T 29-03-2018 THSYN_RS28405 d717be706a7f7e3a382d8d6095715559 383 Gene3D G3DSA:3.40.50.10140 2 159 1.8E-8 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS28405 d717be706a7f7e3a382d8d6095715559 383 Pfam PF08357 SEFIR domain 10 140 2.1E-10 T 29-03-2018 IPR013568 SEFIR domain THSYN_RS30720 4aa415f0e8172b79667820dd426b2ca4 589 Gene3D G3DSA:3.50.50.60 9 487 5.0E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS30720 4aa415f0e8172b79667820dd426b2ca4 589 SUPERFAMILY SSF51905 28 256 6.88E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS30720 4aa415f0e8172b79667820dd426b2ca4 589 Pfam PF06100 MCRA family 22 520 2.9E-216 T 29-03-2018 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 THSYN_RS06885 6969417600b4d4d78ac3338e53b3ece9 153 Gene3D G3DSA:3.30.300.20 1 145 2.2E-16 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta THSYN_RS06885 6969417600b4d4d78ac3338e53b3ece9 153 Pfam PF02566 OsmC-like protein 40 139 2.8E-8 T 29-03-2018 IPR003718 OsmC/Ohr family THSYN_RS06885 6969417600b4d4d78ac3338e53b3ece9 153 SUPERFAMILY SSF82784 7 141 3.01E-17 T 29-03-2018 IPR003718 OsmC/Ohr family THSYN_RS21385 a2f27921bc9da4eeb7c728b0957dd25f 796 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 405 582 2.6E-81 T 29-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 THSYN_RS21385 a2f27921bc9da4eeb7c728b0957dd25f 796 ProSitePatterns PS60002 Phosphoketolase signature 1. 150 156 - T 29-03-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 THSYN_RS21385 a2f27921bc9da4eeb7c728b0957dd25f 796 SUPERFAMILY SSF52518 382 595 1.18E-23 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS21385 a2f27921bc9da4eeb7c728b0957dd25f 796 Pfam PF09363 XFP C-terminal domain 593 794 8.7E-89 T 29-03-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 THSYN_RS21385 a2f27921bc9da4eeb7c728b0957dd25f 796 PIRSF PIRSF017245 1 796 0.0 T 29-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 THSYN_RS21385 a2f27921bc9da4eeb7c728b0957dd25f 796 Gene3D G3DSA:3.40.50.970 384 608 1.4E-33 T 29-03-2018 THSYN_RS21385 a2f27921bc9da4eeb7c728b0957dd25f 796 Hamap MF_01403 Probable phosphoketolase. 11 796 39.807 T 29-03-2018 IPR023962 Probable phosphoketolase THSYN_RS21385 a2f27921bc9da4eeb7c728b0957dd25f 796 Pfam PF09364 XFP N-terminal domain 15 390 9.1E-187 T 29-03-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal THSYN_RS21385 a2f27921bc9da4eeb7c728b0957dd25f 796 Gene3D G3DSA:3.40.50.920 613 796 1.5E-77 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS21385 a2f27921bc9da4eeb7c728b0957dd25f 796 Gene3D G3DSA:3.40.50.970 3 383 1.6E-86 T 29-03-2018 THSYN_RS21385 a2f27921bc9da4eeb7c728b0957dd25f 796 SUPERFAMILY SSF52518 9 375 2.02E-73 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS10245 eb3b850ec8998d1b4ba3a25abd574a7e 227 Gene3D G3DSA:3.40.1350.10 7 218 2.5E-11 T 29-03-2018 THSYN_RS10245 eb3b850ec8998d1b4ba3a25abd574a7e 227 SUPERFAMILY SSF52980 25 227 2.68E-31 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS12430 f304bb0b06d84c3960a136be49965808 401 Gene3D G3DSA:3.40.640.10 86 287 4.1E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS12430 f304bb0b06d84c3960a136be49965808 401 SUPERFAMILY SSF53383 68 393 1.46E-72 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS12430 f304bb0b06d84c3960a136be49965808 401 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 257 266 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 THSYN_RS12430 f304bb0b06d84c3960a136be49965808 401 Gene3D G3DSA:3.90.1150.10 288 395 3.7E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS12430 f304bb0b06d84c3960a136be49965808 401 Pfam PF00155 Aminotransferase class I and II 115 380 2.2E-43 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THSYN_RS28105 9ddcf334b57cff1f321a9c01aeec91c8 136 Gene3D G3DSA:3.30.460.10 1 109 1.1E-10 T 29-03-2018 THSYN_RS28105 9ddcf334b57cff1f321a9c01aeec91c8 136 SUPERFAMILY SSF81301 11 99 1.44E-8 T 29-03-2018 THSYN_RS17590 a8c79c402ea20e0dd3616c5a759bb29a 282 Pfam PF01548 Transposase 24 177 3.6E-7 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THSYN_RS07075 f4c9fdac4894e9926107754c98b898f4 131 Gene3D G3DSA:1.20.120.330 2 127 1.7E-16 T 29-03-2018 THSYN_RS07075 f4c9fdac4894e9926107754c98b898f4 131 SUPERFAMILY SSF81593 33 124 3.73E-13 T 29-03-2018 THSYN_RS07075 f4c9fdac4894e9926107754c98b898f4 131 Pfam PF05168 HEPN domain 32 119 3.9E-13 T 29-03-2018 IPR007842 HEPN domain THSYN_RS16315 6f9a149d018a5ad500f6d35f4af9ff38 429 SUPERFAMILY SSF55681 7 322 6.22E-56 T 29-03-2018 THSYN_RS16315 6f9a149d018a5ad500f6d35f4af9ff38 429 Pfam PF13393 Histidyl-tRNA synthetase 11 321 7.6E-117 T 29-03-2018 THSYN_RS16315 6f9a149d018a5ad500f6d35f4af9ff38 429 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 14 323 4.0E-83 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 THSYN_RS16315 6f9a149d018a5ad500f6d35f4af9ff38 429 Gene3D G3DSA:3.30.930.10 19 313 5.2E-48 T 29-03-2018 THSYN_RS16315 6f9a149d018a5ad500f6d35f4af9ff38 429 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 18 376 31.635 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 THSYN_RS18580 6de080d9097b30ed33a8880edadf2857 618 Gene3D G3DSA:3.40.1440.10 15 110 1.3E-21 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily THSYN_RS18580 6de080d9097b30ed33a8880edadf2857 618 SUPERFAMILY SSF47781 524 613 7.63E-19 T 29-03-2018 IPR010994 RuvA domain 2-like THSYN_RS18580 6de080d9097b30ed33a8880edadf2857 618 Hamap MF_00203 UvrABC system protein C [uvrC]. 14 610 28.586 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 THSYN_RS18580 6de080d9097b30ed33a8880edadf2857 618 Pfam PF01541 GIY-YIG catalytic domain 29 101 1.4E-7 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily THSYN_RS18580 6de080d9097b30ed33a8880edadf2857 618 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 19 591 4.0E-182 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 THSYN_RS18580 6de080d9097b30ed33a8880edadf2857 618 Pfam PF02151 UvrB/uvrC motif 214 247 1.8E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 THSYN_RS18580 6de080d9097b30ed33a8880edadf2857 618 SUPERFAMILY SSF82771 28 109 3.01E-19 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily THSYN_RS18580 6de080d9097b30ed33a8880edadf2857 618 Gene3D G3DSA:1.10.150.20 557 616 5.2E-12 T 29-03-2018 THSYN_RS18580 6de080d9097b30ed33a8880edadf2857 618 SMART SM00465 27 107 5.8E-17 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily THSYN_RS18580 6de080d9097b30ed33a8880edadf2857 618 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 389 545 2.7E-53 T 29-03-2018 IPR001162 UvrC family homology region THSYN_RS18580 6de080d9097b30ed33a8880edadf2857 618 Gene3D G3DSA:4.10.860.10 191 248 2.9E-14 T 29-03-2018 IPR001943 UVR domain GO:0005515 THSYN_RS18580 6de080d9097b30ed33a8880edadf2857 618 SUPERFAMILY SSF46600 200 252 1.7E-12 T 29-03-2018 IPR001943 UVR domain GO:0005515 THSYN_RS30840 fe76a319f61b0da3894601c73014e951 111 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 108 1.1E-28 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS30840 fe76a319f61b0da3894601c73014e951 111 SUPERFAMILY SSF50118 1 111 3.49E-32 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS30840 fe76a319f61b0da3894601c73014e951 111 Gene3D G3DSA:2.30.30.110 1 111 2.9E-31 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS30840 fe76a319f61b0da3894601c73014e951 111 PIRSF PIRSF033490 1 111 1.5E-37 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS08015 063366bd199d59becbcc6f9c5c211489 542 Gene3D G3DSA:1.25.40.70 5 91 0.068 T 29-03-2018 THSYN_RS08015 063366bd199d59becbcc6f9c5c211489 542 Gene3D G3DSA:1.25.40.70 101 181 0.036 T 29-03-2018 THSYN_RS08015 063366bd199d59becbcc6f9c5c211489 542 Gene3D G3DSA:1.10.3470.10 182 529 1.5E-56 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like THSYN_RS08015 063366bd199d59becbcc6f9c5c211489 542 Pfam PF02653 Branched-chain amino acid transport system / permease component 253 524 7.5E-53 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THSYN_RS08015 063366bd199d59becbcc6f9c5c211489 542 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 251 538 4.0E-130 T 29-03-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type THSYN_RS08015 063366bd199d59becbcc6f9c5c211489 542 SUPERFAMILY SSF48371 139 240 1.92E-6 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS08015 063366bd199d59becbcc6f9c5c211489 542 SUPERFAMILY SSF48371 31 74 1.92E-6 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS00405 aae10b386bdf1d3db9225f07b8160800 215 Gene3D G3DSA:3.40.50.10420 32 214 1.4E-38 T 29-03-2018 THSYN_RS00405 aae10b386bdf1d3db9225f07b8160800 215 SUPERFAMILY SSF100950 33 214 1.21E-39 T 29-03-2018 THSYN_RS00405 aae10b386bdf1d3db9225f07b8160800 215 Pfam PF02589 LUD domain 39 214 1.5E-29 T 29-03-2018 IPR003741 LUD domain THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 PRINTS PR00364 Disease resistance protein signature 419 434 5.2E-6 T 29-03-2018 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 PRINTS PR00364 Disease resistance protein signature 598 612 5.2E-6 T 29-03-2018 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 PRINTS PR00364 Disease resistance protein signature 506 520 5.2E-6 T 29-03-2018 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 Pfam PF13424 Tetratricopeptide repeat 901 969 8.9E-11 T 29-03-2018 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 Gene3D G3DSA:3.30.70.100 904 939 1.4E-8 T 29-03-2018 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 Gene3D G3DSA:1.25.40.10 988 1028 0.1 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 SMART SM00028 938 971 120.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 SMART SM00028 898 931 0.076 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 SMART SM00028 857 890 0.77 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 Gene3D G3DSA:1.10.150.200 799 903 5.8E-7 T 29-03-2018 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 Gene3D G3DSA:1.10.150.200 940 987 0.024 T 29-03-2018 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 Pfam PF00149 Calcineurin-like phosphoesterase 9 264 7.2E-9 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 SUPERFAMILY SSF56300 4 104 2.06E-15 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 SUPERFAMILY SSF56300 143 267 2.06E-15 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 SUPERFAMILY SSF52540 388 614 6.66E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 Gene3D G3DSA:3.40.50.300 383 554 1.6E-17 T 29-03-2018 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 SUPERFAMILY SSF48452 896 1026 1.69E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 Gene3D G3DSA:3.60.21.10 4 304 1.2E-15 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS16660 187975a9634d63192732a99dbd6e4f3d 1028 SUPERFAMILY SSF48452 819 928 2.19E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS21675 f314f53a1ec03e8d08492e465c17d6ed 98 Gene3D G3DSA:1.20.5.780 15 92 1.7E-19 T 29-03-2018 THSYN_RS21675 f314f53a1ec03e8d08492e465c17d6ed 98 SUPERFAMILY SSF47598 16 82 6.67E-17 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS21675 f314f53a1ec03e8d08492e465c17d6ed 98 Pfam PF08681 Protein of unknown function (DUF1778) 19 82 3.2E-16 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 THSYN_RS29035 bb1e21fb696f263023f565b2e491815a 356 Pfam PF02719 Polysaccharide biosynthesis protein 9 293 6.2E-84 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain THSYN_RS29035 bb1e21fb696f263023f565b2e491815a 356 Gene3D G3DSA:3.40.50.720 2 343 8.3E-50 T 29-03-2018 THSYN_RS29035 bb1e21fb696f263023f565b2e491815a 356 SUPERFAMILY SSF51735 1 277 2.65E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS02680 000b407c295f6df392af4b15109d7f63 818 Pfam PF01804 Penicillin amidase 47 800 1.3E-178 T 29-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 THSYN_RS02680 000b407c295f6df392af4b15109d7f63 818 Gene3D G3DSA:1.10.439.10 17 181 2.8E-53 T 29-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 THSYN_RS02680 000b407c295f6df392af4b15109d7f63 818 PIRSF PIRSF001227 6 810 4.6E-151 T 29-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 THSYN_RS02680 000b407c295f6df392af4b15109d7f63 818 SUPERFAMILY SSF56235 43 802 1.44E-177 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS02680 000b407c295f6df392af4b15109d7f63 818 Gene3D G3DSA:3.60.20.10 262 641 9.6E-84 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS02680 000b407c295f6df392af4b15109d7f63 818 Gene3D G3DSA:3.60.20.10 665 804 1.9E-13 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS27795 5343266a69982fd9a5a3abc6e90a6aec 145 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 1.4E-50 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 THSYN_RS27795 5343266a69982fd9a5a3abc6e90a6aec 145 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 32.652 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 THSYN_RS27795 5343266a69982fd9a5a3abc6e90a6aec 145 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 4 144 4.6E-50 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 THSYN_RS27795 5343266a69982fd9a5a3abc6e90a6aec 145 SUPERFAMILY SSF69500 1 144 1.19E-50 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain THSYN_RS27795 5343266a69982fd9a5a3abc6e90a6aec 145 Gene3D G3DSA:3.50.80.10 1 145 7.7E-50 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain THSYN_RS21445 489a9eb2d0b5a8b2cb555cc4c78862bd 76 SUPERFAMILY SSF140931 7 64 2.62E-11 T 29-03-2018 IPR003812 Fido domain THSYN_RS21445 489a9eb2d0b5a8b2cb555cc4c78862bd 76 Pfam PF02661 Fic/DOC family 10 64 3.3E-9 T 29-03-2018 IPR003812 Fido domain THSYN_RS21445 489a9eb2d0b5a8b2cb555cc4c78862bd 76 Gene3D G3DSA:1.10.3290.10 2 64 1.6E-9 T 29-03-2018 IPR003812 Fido domain THSYN_RS12285 14650168dd2c75df171514f67ee92432 370 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 55 268 2.9E-32 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS12285 14650168dd2c75df171514f67ee92432 370 Pfam PF00529 HlyD membrane-fusion protein of T1SS 19 337 1.7E-10 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS12285 14650168dd2c75df171514f67ee92432 370 SUPERFAMILY SSF111369 56 271 1.12E-46 T 29-03-2018 THSYN_RS12285 14650168dd2c75df171514f67ee92432 370 Gene3D G3DSA:2.40.50.100 68 159 1.5E-9 T 29-03-2018 THSYN_RS12285 14650168dd2c75df171514f67ee92432 370 Gene3D G3DSA:2.40.50.100 160 353 3.4E-5 T 29-03-2018 THSYN_RS12285 14650168dd2c75df171514f67ee92432 370 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 43 352 3.2E-76 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS12830 0ad7b59a5f2aa80f2fb584329bcc8485 175 Pfam PF13508 Acetyltransferase (GNAT) domain 81 147 3.3E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS12830 0ad7b59a5f2aa80f2fb584329bcc8485 175 Gene3D G3DSA:3.40.630.30 5 154 4.9E-16 T 29-03-2018 THSYN_RS12830 0ad7b59a5f2aa80f2fb584329bcc8485 175 SUPERFAMILY SSF55729 21 149 3.19E-15 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS29275 83aaaf604e052a5376368d4f9775e767 445 SUPERFAMILY SSF52540 202 363 4.78E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29275 83aaaf604e052a5376368d4f9775e767 445 SUPERFAMILY SSF52540 71 168 4.78E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29275 83aaaf604e052a5376368d4f9775e767 445 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 216 363 1.4E-20 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THSYN_RS29275 83aaaf604e052a5376368d4f9775e767 445 Pfam PF01926 50S ribosome-binding GTPase 217 310 6.4E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS29275 83aaaf604e052a5376368d4f9775e767 445 Gene3D G3DSA:1.20.120.430 279 445 9.4E-30 T 29-03-2018 THSYN_RS29275 83aaaf604e052a5376368d4f9775e767 445 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 10 445 2.9E-93 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 THSYN_RS29275 83aaaf604e052a5376368d4f9775e767 445 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 445 31.615 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 THSYN_RS29275 83aaaf604e052a5376368d4f9775e767 445 Pfam PF12631 MnmE helical domain 121 442 5.1E-52 T 29-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 THSYN_RS29275 83aaaf604e052a5376368d4f9775e767 445 Gene3D G3DSA:3.30.1360.120 2 119 8.4E-41 T 29-03-2018 THSYN_RS29275 83aaaf604e052a5376368d4f9775e767 445 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 118 3.8E-35 T 29-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 THSYN_RS29275 83aaaf604e052a5376368d4f9775e767 445 Gene3D G3DSA:1.20.120.430 120 278 2.5E-23 T 29-03-2018 THSYN_RS31165 e55bbd4029b41fc595925c3789600c4a 387 Gene3D G3DSA:3.40.50.2000 191 363 1.9E-43 T 29-03-2018 THSYN_RS31165 e55bbd4029b41fc595925c3789600c4a 387 Pfam PF00534 Glycosyl transferases group 1 194 358 2.5E-34 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS31165 e55bbd4029b41fc595925c3789600c4a 387 Pfam PF13439 Glycosyltransferase Family 4 14 183 1.6E-30 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS31165 e55bbd4029b41fc595925c3789600c4a 387 Gene3D G3DSA:3.40.50.2000 1 190 1.7E-17 T 29-03-2018 THSYN_RS31165 e55bbd4029b41fc595925c3789600c4a 387 SUPERFAMILY SSF53756 2 380 2.26E-82 T 29-03-2018 THSYN_RS23990 3960e142d337fc8feadde98cbb911523 100 SUPERFAMILY SSF47729 3 92 1.43E-32 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS23990 3960e142d337fc8feadde98cbb911523 100 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 96 1.4E-51 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 THSYN_RS23990 3960e142d337fc8feadde98cbb911523 100 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 31.367 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 THSYN_RS23990 3960e142d337fc8feadde98cbb911523 100 Pfam PF00216 Bacterial DNA-binding protein 3 91 4.5E-33 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS23990 3960e142d337fc8feadde98cbb911523 100 Gene3D G3DSA:4.10.520.10 1 99 3.9E-34 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS23990 3960e142d337fc8feadde98cbb911523 100 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 2.0E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS23990 3960e142d337fc8feadde98cbb911523 100 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 2.0E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS23990 3960e142d337fc8feadde98cbb911523 100 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 2.0E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS23990 3960e142d337fc8feadde98cbb911523 100 SMART SM00411 3 92 5.6E-43 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS23990 3960e142d337fc8feadde98cbb911523 100 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 THSYN_RS32000 87c6790de101eb7dcc53ab9e212b86c5 209 SUPERFAMILY SSF53633 2 138 1.48E-9 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase THSYN_RS32000 87c6790de101eb7dcc53ab9e212b86c5 209 Gene3D G3DSA:3.40.1160.10 1 100 1.5E-7 T 29-03-2018 THSYN_RS12795 7fe9a5f671a03af9416760d3a314512a 673 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 79 104 6.0E-5 T 29-03-2018 THSYN_RS12795 7fe9a5f671a03af9416760d3a314512a 673 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 313 325 6.0E-5 T 29-03-2018 THSYN_RS12795 7fe9a5f671a03af9416760d3a314512a 673 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 6.0E-5 T 29-03-2018 THSYN_RS12795 7fe9a5f671a03af9416760d3a314512a 673 Pfam PF00361 Proton-conducting membrane transporter 134 422 2.7E-58 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS19630 5d6ab582810d4519f5356216c8d4d349 315 Gene3D G3DSA:3.10.50.40 146 271 9.7E-34 T 29-03-2018 THSYN_RS19630 5d6ab582810d4519f5356216c8d4d349 315 SUPERFAMILY SSF109998 49 183 7.45E-12 T 29-03-2018 IPR027304 Trigger factor/SurA domain THSYN_RS19630 5d6ab582810d4519f5356216c8d4d349 315 SUPERFAMILY SSF54534 147 244 6.54E-25 T 29-03-2018 THSYN_RS19630 5d6ab582810d4519f5356216c8d4d349 315 Pfam PF13145 PPIC-type PPIASE domain 136 259 7.0E-20 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 THSYN_RS00355 e4540333f94e68d9b40a4c40c140804e 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 29-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 THSYN_RS00355 e4540333f94e68d9b40a4c40c140804e 112 SUPERFAMILY SSF54913 1 112 5.08E-47 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THSYN_RS00355 e4540333f94e68d9b40a4c40c140804e 112 PRINTS PR00340 P-II protein signature 52 75 1.3E-43 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS00355 e4540333f94e68d9b40a4c40c140804e 112 PRINTS PR00340 P-II protein signature 83 103 1.3E-43 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS00355 e4540333f94e68d9b40a4c40c140804e 112 PRINTS PR00340 P-II protein signature 23 41 1.3E-43 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS00355 e4540333f94e68d9b40a4c40c140804e 112 PRINTS PR00340 P-II protein signature 2 17 1.3E-43 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS00355 e4540333f94e68d9b40a4c40c140804e 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 29-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 THSYN_RS00355 e4540333f94e68d9b40a4c40c140804e 112 Gene3D G3DSA:3.30.70.120 1 109 4.8E-50 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THSYN_RS00355 e4540333f94e68d9b40a4c40c140804e 112 SMART SM00938 4 105 1.5E-67 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS00355 e4540333f94e68d9b40a4c40c140804e 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 7.1E-44 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS00355 e4540333f94e68d9b40a4c40c140804e 112 PIRSF PIRSF039144 1 112 1.0E-55 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THSYN_RS09035 4137a5c5ceb464e339eda72b5a7225a0 439 Gene3D G3DSA:3.30.565.10 313 439 1.8E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS09035 4137a5c5ceb464e339eda72b5a7225a0 439 SMART SM00387 325 436 5.5E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS09035 4137a5c5ceb464e339eda72b5a7225a0 439 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 434 1.4E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS09035 4137a5c5ceb464e339eda72b5a7225a0 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 395 8.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS09035 4137a5c5ceb464e339eda72b5a7225a0 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 414 8.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS09035 4137a5c5ceb464e339eda72b5a7225a0 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 381 8.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS09035 4137a5c5ceb464e339eda72b5a7225a0 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 433 8.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS09035 4137a5c5ceb464e339eda72b5a7225a0 439 SUPERFAMILY SSF55874 286 434 1.09E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS09035 4137a5c5ceb464e339eda72b5a7225a0 439 Gene3D G3DSA:1.10.287.130 181 312 0.001 T 29-03-2018 THSYN_RS23515 f2da068a067c7d297e1a7e2325e7d9fe 90 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 11 51 3.0E-8 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THSYN_RS23515 f2da068a067c7d297e1a7e2325e7d9fe 90 Pfam PF02609 Exonuclease VII small subunit 12 62 7.5E-19 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THSYN_RS23515 f2da068a067c7d297e1a7e2325e7d9fe 90 Gene3D G3DSA:1.10.287.1040 9 76 1.0E-22 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THSYN_RS23515 f2da068a067c7d297e1a7e2325e7d9fe 90 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 11 71 15.267 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THSYN_RS23515 f2da068a067c7d297e1a7e2325e7d9fe 90 SUPERFAMILY SSF116842 6 73 7.19E-19 T 29-03-2018 THSYN_RS23515 f2da068a067c7d297e1a7e2325e7d9fe 90 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 12 66 1.0E-20 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THSYN_RS15290 958179a938a481c6afe7e3664ef89183 407 Pfam PF12704 MacB-like periplasmic core domain 21 246 2.0E-39 T 29-03-2018 IPR025857 MacB-like periplasmic core domain THSYN_RS15290 958179a938a481c6afe7e3664ef89183 407 Pfam PF02687 FtsX-like permease family 313 400 1.8E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THSYN_RS31090 7db462c5e094627528deadd5ed348ec2 274 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 22 273 5.2E-113 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 THSYN_RS31090 7db462c5e094627528deadd5ed348ec2 274 Gene3D G3DSA:3.40.50.300 17 272 4.8E-53 T 29-03-2018 THSYN_RS31090 7db462c5e094627528deadd5ed348ec2 274 SMART SM00382 46 242 1.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS31090 7db462c5e094627528deadd5ed348ec2 274 SUPERFAMILY SSF52540 13 261 1.17E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31090 7db462c5e094627528deadd5ed348ec2 274 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS31090 7db462c5e094627528deadd5ed348ec2 274 Pfam PF00005 ABC transporter 43 190 2.7E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS19445 61d2018cb4e782d39d71ac4670107a64 313 Gene3D G3DSA:3.40.190.10 176 297 3.0E-13 T 29-03-2018 THSYN_RS19445 61d2018cb4e782d39d71ac4670107a64 313 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 86 99 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 THSYN_RS19445 61d2018cb4e782d39d71ac4670107a64 313 SMART SM00062 63 291 7.7E-51 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS19445 61d2018cb4e782d39d71ac4670107a64 313 SUPERFAMILY SSF53850 35 291 5.82E-56 T 29-03-2018 THSYN_RS19445 61d2018cb4e782d39d71ac4670107a64 313 Gene3D G3DSA:3.40.190.10 28 175 5.9E-31 T 29-03-2018 THSYN_RS19445 61d2018cb4e782d39d71ac4670107a64 313 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 64 289 5.1E-52 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS32305 ef7110d1f19ed9ec3c0c4f4e12b9411c 421 Pfam PF06245 Protein of unknown function (DUF1015) 4 416 1.3E-103 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 THSYN_RS32305 ef7110d1f19ed9ec3c0c4f4e12b9411c 421 PIRSF PIRSF033563 1 420 3.8E-94 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 THSYN_RS28685 416e69dd7ce7d705f1c80a0bce656434 359 Pfam PF00072 Response regulator receiver domain 3 113 2.0E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS28685 416e69dd7ce7d705f1c80a0bce656434 359 Gene3D G3DSA:3.40.50.2300 1 126 1.7E-31 T 29-03-2018 THSYN_RS28685 416e69dd7ce7d705f1c80a0bce656434 359 SUPERFAMILY SSF52172 1 119 3.56E-33 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS28685 416e69dd7ce7d705f1c80a0bce656434 359 SMART SM00448 1 117 2.6E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS28065 adda066bb66d074fdda15f4c25b3899e 250 Gene3D G3DSA:3.40.50.150 2 248 1.1E-42 T 29-03-2018 THSYN_RS28065 adda066bb66d074fdda15f4c25b3899e 250 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 13 248 35.343 T 29-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 THSYN_RS28065 adda066bb66d074fdda15f4c25b3899e 250 SUPERFAMILY SSF53335 17 244 1.21E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS28065 adda066bb66d074fdda15f4c25b3899e 250 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 15 242 9.3E-73 T 29-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 THSYN_RS28065 adda066bb66d074fdda15f4c25b3899e 250 Pfam PF08241 Methyltransferase domain 71 166 8.2E-23 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THSYN_RS09585 ecf4dbe0800536da488a96181bbfc9b7 166 Gene3D G3DSA:3.40.30.10 82 165 1.6E-9 T 29-03-2018 THSYN_RS09585 ecf4dbe0800536da488a96181bbfc9b7 166 SUPERFAMILY SSF52833 14 161 4.47E-45 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS09585 ecf4dbe0800536da488a96181bbfc9b7 166 PIRSF PIRSF000216 4 166 5.9E-47 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09585 ecf4dbe0800536da488a96181bbfc9b7 166 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 21 161 2.8E-42 T 29-03-2018 THSYN_RS09330 d1f8dc4add85b9458dd338d7e8a770b5 232 SUPERFAMILY SSF52788 53 190 3.53E-22 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS09330 d1f8dc4add85b9458dd338d7e8a770b5 232 Gene3D G3DSA:3.40.50.2300 48 200 2.6E-22 T 29-03-2018 THSYN_RS09330 d1f8dc4add85b9458dd338d7e8a770b5 232 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 54 71 2.4E-7 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS09330 d1f8dc4add85b9458dd338d7e8a770b5 232 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 162 177 2.4E-7 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS09330 d1f8dc4add85b9458dd338d7e8a770b5 232 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 144 157 2.4E-7 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS09330 d1f8dc4add85b9458dd338d7e8a770b5 232 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 122 137 2.4E-7 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS09330 d1f8dc4add85b9458dd338d7e8a770b5 232 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 55 187 8.6E-15 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS09330 d1f8dc4add85b9458dd338d7e8a770b5 232 SMART SM00226 52 190 1.3E-5 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS06855 624452b45860151c7f6a6cda0e477034 245 SMART SM00382 29 241 1.7E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS06855 624452b45860151c7f6a6cda0e477034 245 Pfam PF00005 ABC transporter 20 164 2.5E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS06855 624452b45860151c7f6a6cda0e477034 245 Gene3D G3DSA:3.40.50.300 1 241 4.9E-46 T 29-03-2018 THSYN_RS06855 624452b45860151c7f6a6cda0e477034 245 SUPERFAMILY SSF52540 4 228 8.71E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09130 00a8df7ba17f42bc80ca93a1e118e87c 81 Pfam PF03683 Uncharacterised protein family (UPF0175) 21 80 9.3E-15 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS13590 01300eb2328038c94110f0746bc39451 202 Gene3D G3DSA:3.90.180.10 12 190 1.8E-32 T 29-03-2018 THSYN_RS13590 01300eb2328038c94110f0746bc39451 202 Pfam PF16884 N-terminal domain of oxidoreductase 9 110 8.0E-39 T 29-03-2018 THSYN_RS13590 01300eb2328038c94110f0746bc39451 202 SUPERFAMILY SSF50129 151 188 1.93E-44 T 29-03-2018 IPR011032 GroES-like THSYN_RS13590 01300eb2328038c94110f0746bc39451 202 SUPERFAMILY SSF50129 6 119 1.93E-44 T 29-03-2018 IPR011032 GroES-like THSYN_RS13590 01300eb2328038c94110f0746bc39451 202 Pfam PF13602 Zinc-binding dehydrogenase 145 188 5.7E-7 T 29-03-2018 THSYN_RS22585 6cf981fb00e29a1e79e682a58493d7e2 166 SUPERFAMILY SSF49777 5 160 1.7E-44 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein THSYN_RS22585 6cf981fb00e29a1e79e682a58493d7e2 166 Pfam PF01161 Phosphatidylethanolamine-binding protein 16 159 1.1E-34 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein THSYN_RS22585 6cf981fb00e29a1e79e682a58493d7e2 166 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 15 157 5.7E-36 T 29-03-2018 IPR005247 YbhB/YbcL THSYN_RS22585 6cf981fb00e29a1e79e682a58493d7e2 166 Gene3D G3DSA:3.90.280.10 1 162 3.0E-48 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein THSYN_RS21205 88113a52d5ce6f2c8a51e28bfdbee090 301 Gene3D G3DSA:3.30.1490.20 103 170 5.7E-9 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS21205 88113a52d5ce6f2c8a51e28bfdbee090 301 SUPERFAMILY SSF56059 98 288 5.58E-47 T 29-03-2018 THSYN_RS21205 88113a52d5ce6f2c8a51e28bfdbee090 301 Pfam PF08443 RimK-like ATP-grasp domain 97 286 5.1E-63 T 29-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 THSYN_RS21205 88113a52d5ce6f2c8a51e28bfdbee090 301 Gene3D G3DSA:3.30.470.20 171 277 3.0E-32 T 29-03-2018 THSYN_RS21205 88113a52d5ce6f2c8a51e28bfdbee090 301 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 285 9.0E-81 T 29-03-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 THSYN_RS21205 88113a52d5ce6f2c8a51e28bfdbee090 301 Gene3D G3DSA:3.40.50.20 1 102 1.6E-36 T 29-03-2018 THSYN_RS21205 88113a52d5ce6f2c8a51e28bfdbee090 301 Hamap MF_01552 Ribosomal protein S6--L-glutamate ligase [rimK]. 1 295 53.208 T 29-03-2018 IPR023533 Ribosomal protein S6--L-glutamate ligase RimK THSYN_RS02505 c6cd438d37db0d5b27f8452742066243 366 Pfam PF05137 Fimbrial assembly protein (PilN) 286 356 1.1E-6 T 29-03-2018 IPR007813 Fimbrial assembly PilN THSYN_RS02505 c6cd438d37db0d5b27f8452742066243 366 SUPERFAMILY SSF53067 89 187 2.98E-12 T 29-03-2018 THSYN_RS00170 52da1f8736d72af847325aa7a7d9aa95 289 Pfam PF07589 PEP-CTERM motif 259 282 8.7E-6 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS00170 52da1f8736d72af847325aa7a7d9aa95 289 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 260 283 4.9E-4 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS27290 c6fea5eb53bbe89296c1a8e360db488e 483 PIRSF PIRSF000977 1 482 1.8E-192 T 29-03-2018 IPR023607 Exodeoxyribonuclease I GO:0004529 THSYN_RS27290 c6fea5eb53bbe89296c1a8e360db488e 483 SUPERFAMILY SSF53098 4 476 2.46E-112 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS27290 c6fea5eb53bbe89296c1a8e360db488e 483 Pfam PF00929 Exonuclease 7 187 1.7E-18 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THSYN_RS27290 c6fea5eb53bbe89296c1a8e360db488e 483 Pfam PF08411 Exonuclease C-terminal 206 476 9.2E-94 T 29-03-2018 IPR013620 Exodeoxyribonuclease I, C-terminal GO:0006281|GO:0008852 THSYN_RS27290 c6fea5eb53bbe89296c1a8e360db488e 483 Gene3D G3DSA:3.30.420.10 2 195 6.2E-23 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS26560 040d493fa2f9b8b866a2d71dd2c981c4 181 SMART SM00271 6 71 3.6E-8 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS26560 040d493fa2f9b8b866a2d71dd2c981c4 181 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 6 178 21.295 T 29-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 THSYN_RS26560 040d493fa2f9b8b866a2d71dd2c981c4 181 Gene3D G3DSA:1.10.287.110 3 90 3.0E-10 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS26560 040d493fa2f9b8b866a2d71dd2c981c4 181 Gene3D G3DSA:1.20.1280.20 91 178 1.5E-19 T 29-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 THSYN_RS26560 040d493fa2f9b8b866a2d71dd2c981c4 181 SUPERFAMILY SSF47144 86 173 5.89E-13 T 29-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 THSYN_RS26560 040d493fa2f9b8b866a2d71dd2c981c4 181 Pfam PF07743 HSCB C-terminal oligomerisation domain 93 170 6.2E-14 T 29-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 THSYN_RS26560 040d493fa2f9b8b866a2d71dd2c981c4 181 SUPERFAMILY SSF46565 7 79 7.59E-17 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS26560 040d493fa2f9b8b866a2d71dd2c981c4 181 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 18 174 3.8E-29 T 29-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 Gene3D G3DSA:3.20.20.120 128 425 4.1E-102 T 29-03-2018 IPR029065 Enolase C-terminal domain-like THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 ProSitePatterns PS00164 Enolase signature. 333 346 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 Pfam PF03952 Enolase, N-terminal domain 4 133 2.4E-57 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 PIRSF PIRSF001400 1 424 1.0E-184 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 Hamap MF_00318 Enolase [eno]. 2 410 43.837 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 SUPERFAMILY SSF54826 4 135 3.76E-52 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 SMART SM01193 4 134 1.2E-87 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 PRINTS PR00148 Enolase signature 37 51 2.3E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 PRINTS PR00148 Enolase signature 107 123 2.3E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 PRINTS PR00148 Enolase signature 310 321 2.3E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 PRINTS PR00148 Enolase signature 160 173 2.3E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 PRINTS PR00148 Enolase signature 333 347 2.3E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 PRINTS PR00148 Enolase signature 362 379 2.3E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 SUPERFAMILY SSF51604 138 423 3.01E-126 T 29-03-2018 IPR029065 Enolase C-terminal domain-like THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 SMART SM01192 138 424 5.8E-218 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 Pfam PF00113 Enolase, C-terminal TIM barrel domain 139 422 8.3E-132 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 Gene3D G3DSA:3.30.390.10 3 127 1.4E-50 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS20380 e81c66340f3580c082f005e8600ef785 425 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 423 9.2E-203 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THSYN_RS00965 b28d2ea1ff65c0eb0844c3f9111e2e7b 107 Pfam PF14213 STAS-like domain of unknown function (DUF4325) 30 86 1.1E-10 T 29-03-2018 IPR025474 Domain of unknown function DUF4325 THSYN_RS12400 2049ff5270afda4a53dea91e3ef2072c 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 186 7.0E-8 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS12400 2049ff5270afda4a53dea91e3ef2072c 230 Gene3D G3DSA:3.40.50.1000 4 196 2.1E-16 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS12400 2049ff5270afda4a53dea91e3ef2072c 230 SUPERFAMILY SSF56784 3 203 5.7E-22 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS03965 090c96dcc0407da0002ff8791356331e 107 SUPERFAMILY SSF54736 22 106 1.83E-32 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THSYN_RS03965 090c96dcc0407da0002ff8791356331e 107 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 5 102 29.198 T 29-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS THSYN_RS03965 090c96dcc0407da0002ff8791356331e 107 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 25 103 1.8E-34 T 29-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 THSYN_RS03965 090c96dcc0407da0002ff8791356331e 107 Gene3D G3DSA:3.30.1390.10 14 106 4.9E-36 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THSYN_RS14570 75224581ea2443a5484e7fab657d9d9a 267 SMART SM00332 3 247 1.5E-13 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS14570 75224581ea2443a5484e7fab657d9d9a 267 SMART SM00331 12 249 3.3E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS14570 75224581ea2443a5484e7fab657d9d9a 267 Gene3D G3DSA:3.60.40.10 6 249 1.7E-36 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS14570 75224581ea2443a5484e7fab657d9d9a 267 SUPERFAMILY SSF81606 5 249 8.63E-56 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS14570 75224581ea2443a5484e7fab657d9d9a 267 Pfam PF13672 Protein phosphatase 2C 17 205 9.9E-17 T 29-03-2018 THSYN_RS07930 d121a9765cd558b80fedacb22ef8eee8 926 Pfam PF04851 Type III restriction enzyme, res subunit 157 344 1.2E-34 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS07930 d121a9765cd558b80fedacb22ef8eee8 926 Gene3D G3DSA:3.40.50.300 128 364 3.9E-28 T 29-03-2018 THSYN_RS07930 d121a9765cd558b80fedacb22ef8eee8 926 Pfam PF00271 Helicase conserved C-terminal domain 448 550 1.0E-4 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS07930 d121a9765cd558b80fedacb22ef8eee8 926 SMART SM00487 154 376 5.5E-17 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS07930 d121a9765cd558b80fedacb22ef8eee8 926 Pfam PF08463 EcoEI R protein C-terminal 746 924 4.1E-53 T 29-03-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 THSYN_RS07930 d121a9765cd558b80fedacb22ef8eee8 926 SUPERFAMILY SSF52540 173 276 2.17E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07930 d121a9765cd558b80fedacb22ef8eee8 926 SUPERFAMILY SSF52540 420 553 2.17E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07930 d121a9765cd558b80fedacb22ef8eee8 926 SUPERFAMILY SSF52540 306 346 2.17E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07930 d121a9765cd558b80fedacb22ef8eee8 926 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 46 117 1.3E-6 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THSYN_RS07930 d121a9765cd558b80fedacb22ef8eee8 926 Gene3D G3DSA:3.40.50.300 421 564 2.7E-8 T 29-03-2018 THSYN_RS28825 4b5c70cc00fe3f2983302125d5ade574 326 Gene3D G3DSA:1.10.4080.10 1 312 1.9E-89 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 THSYN_RS28825 4b5c70cc00fe3f2983302125d5ade574 326 Pfam PF03747 ADP-ribosylglycohydrolase 11 285 2.2E-70 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 THSYN_RS28825 4b5c70cc00fe3f2983302125d5ade574 326 SUPERFAMILY SSF101478 3 306 4.18E-75 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 Gene3D G3DSA:3.40.50.300 938 1161 5.6E-31 T 29-03-2018 THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1158 22.836 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1149 6.8E-65 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 Gene3D G3DSA:3.40.50.300 1 221 8.4E-37 T 29-03-2018 THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 PIRSF PIRSF005719 588 1164 2.2E-126 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 PIRSF PIRSF005719 1 559 2.8E-133 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 Gene3D G3DSA:1.20.5.170 399 501 1.5E-4 T 29-03-2018 THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 SUPERFAMILY SSF52540 1 213 2.65E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 SUPERFAMILY SSF52540 1042 1158 2.65E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 Gene3D G3DSA:1.20.5.340 738 815 0.029 T 29-03-2018 THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 Gene3D G3DSA:1.20.5.340 816 937 8.1E-5 T 29-03-2018 THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 Gene3D G3DSA:1.20.5.340 610 737 0.0037 T 29-03-2018 THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 Gene3D G3DSA:1.20.5.340 222 344 0.093 T 29-03-2018 THSYN_RS27335 0bc0d2e3d6a51753b9ad89513fc6aa37 1166 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1156 0.0 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 THSYN_RS28375 2d6e448f41c9cc7634fabb7779bc1b85 285 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 162 268 1.9E-30 T 29-03-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 THSYN_RS28375 2d6e448f41c9cc7634fabb7779bc1b85 285 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 19 273 38.066 T 29-03-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 THSYN_RS28375 2d6e448f41c9cc7634fabb7779bc1b85 285 Pfam PF02649 Type I GTP cyclohydrolase folE2 20 268 3.6E-97 T 29-03-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 THSYN_RS28375 2d6e448f41c9cc7634fabb7779bc1b85 285 Gene3D G3DSA:3.10.270.10 18 271 1.7E-106 T 29-03-2018 THSYN_RS17395 4fe8c844e853d5f22ee9019a39fc545a 195 SMART SM00855 5 151 8.9E-11 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THSYN_RS17395 4fe8c844e853d5f22ee9019a39fc545a 195 SUPERFAMILY SSF53254 4 188 7.92E-40 T 29-03-2018 IPR029033 Histidine phosphatase superfamily THSYN_RS17395 4fe8c844e853d5f22ee9019a39fc545a 195 Gene3D G3DSA:3.40.50.1240 1 193 3.5E-36 T 29-03-2018 IPR029033 Histidine phosphatase superfamily THSYN_RS17395 4fe8c844e853d5f22ee9019a39fc545a 195 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 178 1.1E-35 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THSYN_RS16460 1861d1a572620ba5702ab6820bc7b528 245 SUPERFAMILY SSF53335 21 198 1.22E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS16460 1861d1a572620ba5702ab6820bc7b528 245 Pfam PF08241 Methyltransferase domain 38 123 1.5E-12 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THSYN_RS16460 1861d1a572620ba5702ab6820bc7b528 245 Gene3D G3DSA:3.40.50.150 53 186 1.9E-19 T 29-03-2018 THSYN_RS02125 698a6cfced40d4e38283d5f527ab5fea 428 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 416 1.0E-175 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS02125 698a6cfced40d4e38283d5f527ab5fea 428 SUPERFAMILY SSF55205 1 417 1.8E-139 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 THSYN_RS02125 698a6cfced40d4e38283d5f527ab5fea 428 Gene3D G3DSA:3.65.10.10 21 220 9.9E-50 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 THSYN_RS02125 698a6cfced40d4e38283d5f527ab5fea 428 Gene3D G3DSA:3.65.10.10 221 419 2.6E-43 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 THSYN_RS02125 698a6cfced40d4e38283d5f527ab5fea 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 4.1E-112 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 THSYN_RS02125 698a6cfced40d4e38283d5f527ab5fea 428 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 44.226 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS23400 ef33c30dd3487c9001e923142a4ceb17 281 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 8 251 37.328 T 29-03-2018 IPR017689 Outer membrane protein assembly factor BamD THSYN_RS23400 ef33c30dd3487c9001e923142a4ceb17 281 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 11 252 7.0E-85 T 29-03-2018 IPR017689 Outer membrane protein assembly factor BamD THSYN_RS23400 ef33c30dd3487c9001e923142a4ceb17 281 SUPERFAMILY SSF48452 40 126 1.61E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23400 ef33c30dd3487c9001e923142a4ceb17 281 Gene3D G3DSA:1.25.20.10 38 266 1.1E-16 T 29-03-2018 THSYN_RS23400 ef33c30dd3487c9001e923142a4ceb17 281 Pfam PF13525 Outer membrane lipoprotein 41 244 1.9E-67 T 29-03-2018 THSYN_RS03360 894b56305133e15bd67ae17ac6afc643 324 Gene3D G3DSA:1.10.8.300 206 321 2.6E-32 T 29-03-2018 THSYN_RS03360 894b56305133e15bd67ae17ac6afc643 324 SUPERFAMILY SSF52540 11 296 6.4E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03360 894b56305133e15bd67ae17ac6afc643 324 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 171 2.4E-62 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 THSYN_RS03360 894b56305133e15bd67ae17ac6afc643 324 PIRSF PIRSF002849 4 324 3.1E-125 T 29-03-2018 THSYN_RS03360 894b56305133e15bd67ae17ac6afc643 324 Gene3D G3DSA:3.40.50.300 22 188 4.1E-25 T 29-03-2018 THSYN_RS03495 e10ffac242da16cb898d47bde132c8fe 348 Pfam PF02353 Mycolic acid cyclopropane synthetase 70 331 2.8E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS03495 e10ffac242da16cb898d47bde132c8fe 348 Gene3D G3DSA:3.40.50.150 66 342 3.4E-47 T 29-03-2018 THSYN_RS03495 e10ffac242da16cb898d47bde132c8fe 348 SUPERFAMILY SSF53335 71 339 3.35E-57 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS06455 d5984abf4c4867b13a119f271aabe847 549 Gene3D G3DSA:3.90.1580.10 406 470 7.1E-17 T 29-03-2018 THSYN_RS06455 d5984abf4c4867b13a119f271aabe847 549 Gene3D G3DSA:3.90.1580.10 8 179 4.4E-22 T 29-03-2018 THSYN_RS06455 d5984abf4c4867b13a119f271aabe847 549 Gene3D G3DSA:3.90.1580.10 471 549 1.2E-7 T 29-03-2018 THSYN_RS06455 d5984abf4c4867b13a119f271aabe847 549 Gene3D G3DSA:3.90.1580.10 339 405 5.0E-10 T 29-03-2018 THSYN_RS06455 d5984abf4c4867b13a119f271aabe847 549 Gene3D G3DSA:1.10.101.10 196 292 5.4E-8 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS06455 d5984abf4c4867b13a119f271aabe847 549 SUPERFAMILY SSF47090 203 288 1.37E-6 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS06455 d5984abf4c4867b13a119f271aabe847 549 Pfam PF03781 Sulfatase-modifying factor enzyme 1 37 168 8.8E-19 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS06455 d5984abf4c4867b13a119f271aabe847 549 Pfam PF03781 Sulfatase-modifying factor enzyme 1 472 546 1.3E-6 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS06455 d5984abf4c4867b13a119f271aabe847 549 Pfam PF03781 Sulfatase-modifying factor enzyme 1 357 458 6.2E-23 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS06455 d5984abf4c4867b13a119f271aabe847 549 SUPERFAMILY SSF56436 39 170 1.41E-22 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS06455 d5984abf4c4867b13a119f271aabe847 549 SUPERFAMILY SSF56436 354 549 7.16E-45 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS03345 ecd57cda968ca9d3bf1f65cf59e09422 333 SUPERFAMILY SSF53300 86 266 1.93E-39 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS03345 ecd57cda968ca9d3bf1f65cf59e09422 333 Gene3D G3DSA:3.40.50.410 86 307 2.4E-45 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS03345 ecd57cda968ca9d3bf1f65cf59e09422 333 Pfam PF00092 von Willebrand factor type A domain 89 281 7.0E-28 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS03345 ecd57cda968ca9d3bf1f65cf59e09422 333 SMART SM00327 87 284 7.2E-26 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS29815 699d9e0b00b103763c3ef159070d93ea 149 Pfam PF07883 Cupin domain 51 118 9.5E-11 T 29-03-2018 IPR013096 Cupin 2, conserved barrel THSYN_RS29815 699d9e0b00b103763c3ef159070d93ea 149 Gene3D G3DSA:2.60.120.10 6 149 1.4E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS29815 699d9e0b00b103763c3ef159070d93ea 149 SUPERFAMILY SSF51182 30 126 3.63E-16 T 29-03-2018 IPR011051 RmlC-like cupin domain THSYN_RS30955 d8e0808412c98dc55858683a42c5448a 71 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 6 54 1.0E-9 T 29-03-2018 THSYN_RS30955 d8e0808412c98dc55858683a42c5448a 71 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 6 69 3.9E-16 T 29-03-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 THSYN_RS25750 1c24e86d04d72bef8e12001c3a7f3435 1366 Gene3D G3DSA:2.160.20.10 124 662 0.014 T 29-03-2018 IPR012334 Pectin lyase fold THSYN_RS25750 1c24e86d04d72bef8e12001c3a7f3435 1366 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1079 1310 4.0E-22 T 29-03-2018 IPR007452 Translocation and assembly module TamB THSYN_RS19430 6a15857a912b1a124eeeb5eeef1e8a98 344 Pfam PF01867 CRISPR associated protein Cas1 8 299 6.0E-99 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THSYN_RS19430 6a15857a912b1a124eeeb5eeef1e8a98 344 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 329 26.859 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THSYN_RS19430 6a15857a912b1a124eeeb5eeef1e8a98 344 TIGRFAM TIGR03640 cas1_DVULG: CRISPR-associated endonuclease Cas1, subtype I-C/DVULG 4 342 3.2E-149 T 29-03-2018 IPR019856 CRISPR-associated protein Cas1, DVULG subtype GO:0004520|GO:0043571|GO:0046872 THSYN_RS19430 6a15857a912b1a124eeeb5eeef1e8a98 344 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 7 335 7.2E-76 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THSYN_RS02650 e0b32038e133ae01470cd95f99ae8f6c 309 SUPERFAMILY SSF74650 22 284 8.16E-58 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 THSYN_RS02650 e0b32038e133ae01470cd95f99ae8f6c 309 Pfam PF01263 Aldose 1-epimerase 30 286 7.2E-32 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 THSYN_RS02650 e0b32038e133ae01470cd95f99ae8f6c 309 Gene3D G3DSA:2.70.98.10 17 301 1.2E-54 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 THSYN_RS02650 e0b32038e133ae01470cd95f99ae8f6c 309 PIRSF PIRSF016020 15 302 1.3E-49 T 29-03-2018 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 THSYN_RS10855 03cedeed5a8178e06fa73813a7379a3d 136 SUPERFAMILY SSF54427 32 131 2.93E-35 T 29-03-2018 IPR032710 NTF2-like domain THSYN_RS10855 03cedeed5a8178e06fa73813a7379a3d 136 SUPERFAMILY SSF103642 7 27 1.03E-5 T 29-03-2018 THSYN_RS10855 03cedeed5a8178e06fa73813a7379a3d 136 Gene3D G3DSA:3.10.450.50 22 134 5.1E-45 T 29-03-2018 THSYN_RS10855 03cedeed5a8178e06fa73813a7379a3d 136 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 8 131 27.898 T 29-03-2018 IPR023006 Uncharacterised protein family UPF0225 THSYN_RS10855 03cedeed5a8178e06fa73813a7379a3d 136 Gene3D G3DSA:3.10.450.50 2 21 5.1E-5 T 29-03-2018 THSYN_RS10855 03cedeed5a8178e06fa73813a7379a3d 136 Pfam PF02810 SEC-C motif 10 26 6.3E-6 T 29-03-2018 IPR004027 SEC-C motif THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 Pfam PF12894 Anaphase-promoting complex subunit 4 WD40 domain 105 182 1.9E-9 T 29-03-2018 IPR024977 Anaphase-promoting complex subunit 4, WD40 domain THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 196 210 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 Gene3D G3DSA:2.40.50.140 254 303 2.5E-16 T 29-03-2018 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 Gene3D G3DSA:2.40.50.140 174 202 1.8E-6 T 29-03-2018 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 Gene3D G3DSA:2.40.50.140 9 38 5.9E-6 T 29-03-2018 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 SUPERFAMILY SSF50978 11 292 1.83E-86 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 Gene3D G3DSA:2.80.10.50 230 253 2.6E-12 T 29-03-2018 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 154 168 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 71 85 - T 29-03-2018 IPR019775 WD40 repeat, conserved site THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 Pfam PF00400 WD domain, G-beta repeat 221 251 1.8E-4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 Pfam PF00400 WD domain, G-beta repeat 257 292 1.2E-6 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 Pfam PF00400 WD domain, G-beta repeat 15 40 0.24 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 Pfam PF00400 WD domain, G-beta repeat 46 84 3.1E-10 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 PRINTS PR00320 G protein beta WD-40 repeat signature 113 127 5.9E-7 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 PRINTS PR00320 G protein beta WD-40 repeat signature 154 168 5.9E-7 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 PRINTS PR00320 G protein beta WD-40 repeat signature 71 85 5.9E-7 T 29-03-2018 IPR020472 G-protein beta WD-40 repeat THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 PIRSF PIRSF002394 96 302 1.5E-40 T 29-03-2018 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 PIRSF PIRSF002394 8 44 0.0033 T 29-03-2018 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 PIRSF PIRSF002394 23 200 1.1E-34 T 29-03-2018 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 SMART SM00320 171 209 1.4 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 SMART SM00320 128 167 8.1E-11 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 SMART SM00320 212 251 7.1E-9 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 SMART SM00320 254 293 4.3E-7 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 SMART SM00320 87 126 1.5E-7 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 SMART SM00320 2 42 0.17 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 SMART SM00320 45 84 3.5E-13 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 Gene3D G3DSA:1.10.10.670 39 79 5.1E-20 T 29-03-2018 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 Gene3D G3DSA:1.10.10.670 125 173 3.1E-19 T 29-03-2018 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 Gene3D G3DSA:1.10.10.670 80 124 1.2E-16 T 29-03-2018 THSYN_RS09140 2ff8570982d8fd8935207de045a9fe39 343 Gene3D G3DSA:1.10.10.670 203 229 7.7E-8 T 29-03-2018 THSYN_RS04005 cb233803d8eaa1468a4e122087ef7773 58 SUPERFAMILY SSF69047 1 56 1.7E-10 T 29-03-2018 IPR008462 CsbD-like domain THSYN_RS04005 cb233803d8eaa1468a4e122087ef7773 58 Gene3D G3DSA:1.10.1470.10 1 57 1.2E-11 T 29-03-2018 IPR008462 CsbD-like domain THSYN_RS04005 cb233803d8eaa1468a4e122087ef7773 58 Pfam PF05532 CsbD-like 4 50 2.3E-10 T 29-03-2018 IPR008462 CsbD-like domain THSYN_RS13425 1009b60987eeda0ec764fbe211ee8564 241 Gene3D G3DSA:3.40.50.2020 79 241 2.2E-23 T 29-03-2018 THSYN_RS13425 1009b60987eeda0ec764fbe211ee8564 241 SUPERFAMILY SSF53271 67 239 1.01E-30 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like THSYN_RS25395 f9fa2beccbc8917dd477b0832a59f94a 157 SUPERFAMILY SSF46785 2 103 1.34E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25395 f9fa2beccbc8917dd477b0832a59f94a 157 TIGRFAM TIGR04176 MarR_EPS: EPS-associated transcriptional regulator, MarR family 2 86 1.4E-35 T 29-03-2018 IPR026433 EPS-associated transcriptional regulator, MarR family THSYN_RS25395 f9fa2beccbc8917dd477b0832a59f94a 157 Gene3D G3DSA:1.10.10.10 1 130 6.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25395 f9fa2beccbc8917dd477b0832a59f94a 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 45 1.4E-10 T 29-03-2018 THSYN_RS31400 9ff234f3557924fd10b0922947bb8fe2 76 SUPERFAMILY SSF56918 1 48 2.3E-18 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31400 9ff234f3557924fd10b0922947bb8fe2 76 Gene3D G3DSA:4.10.220.20 1 49 2.1E-23 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31400 9ff234f3557924fd10b0922947bb8fe2 76 PRINTS PR00673 Light harvesting protein A chain signature 3 10 1.7E-12 T 29-03-2018 IPR018332 Antenna complex, alpha subunit THSYN_RS31400 9ff234f3557924fd10b0922947bb8fe2 76 PRINTS PR00673 Light harvesting protein A chain signature 10 29 1.7E-12 T 29-03-2018 IPR018332 Antenna complex, alpha subunit THSYN_RS31400 9ff234f3557924fd10b0922947bb8fe2 76 PRINTS PR00673 Light harvesting protein A chain signature 29 40 1.7E-12 T 29-03-2018 IPR018332 Antenna complex, alpha subunit THSYN_RS31400 9ff234f3557924fd10b0922947bb8fe2 76 ProSitePatterns PS00968 Antenna complexes alpha subunits signature. 23 41 - T 29-03-2018 IPR002361 Antenna complex, alpha subunit conserved site GO:0016021|GO:0019684|GO:0019866|GO:0030077|GO:0045156 THSYN_RS31400 9ff234f3557924fd10b0922947bb8fe2 76 Pfam PF00556 Antenna complex alpha/beta subunit 1 41 7.8E-17 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS08270 76a277a91289f6a48b7ece74464bda00 249 TIGRFAM TIGR03694 exosort_acyl: N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated 10 245 7.9E-57 T 29-03-2018 IPR022484 PEP-CTERM/exosortase system-associated acyltransferase, predicted THSYN_RS08270 76a277a91289f6a48b7ece74464bda00 249 SUPERFAMILY SSF55729 14 217 1.77E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS08270 76a277a91289f6a48b7ece74464bda00 249 Gene3D G3DSA:3.40.630.30 15 231 1.3E-30 T 29-03-2018 THSYN_RS08270 76a277a91289f6a48b7ece74464bda00 249 Pfam PF13444 Acetyltransferase (GNAT) domain 33 139 7.3E-17 T 29-03-2018 THSYN_RS00325 8d09a0caf4a516f2e58c9db87fc8e73a 177 Pfam PF11159 Protein of unknown function (DUF2939) 32 119 2.8E-13 T 29-03-2018 IPR021330 Protein of unknown function DUF2939 THSYN_RS08600 4f129caa59cdef65bdb58ef47c55b21d 205 Gene3D G3DSA:3.90.1570.10 18 184 3.4E-23 T 29-03-2018 THSYN_RS08600 4f129caa59cdef65bdb58ef47c55b21d 205 Pfam PF05685 Putative restriction endonuclease 27 172 8.2E-22 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS08600 4f129caa59cdef65bdb58ef47c55b21d 205 SUPERFAMILY SSF52980 28 168 3.81E-9 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS28605 1d25a6845abd84eca9fc77bbc6ffb2b2 92 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 56 3.8E-8 T 29-03-2018 THSYN_RS28605 1d25a6845abd84eca9fc77bbc6ffb2b2 92 SUPERFAMILY SSF143120 1 78 7.72E-18 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS28605 1d25a6845abd84eca9fc77bbc6ffb2b2 92 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 72 2.0E-16 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS28605 1d25a6845abd84eca9fc77bbc6ffb2b2 92 Gene3D G3DSA:3.40.1620.10 1 39 2.4E-12 T 29-03-2018 THSYN_RS06920 20d673d1ded14c36978246325d96e53c 480 SUPERFAMILY SSF101960 36 477 2.75E-136 T 29-03-2018 THSYN_RS06920 20d673d1ded14c36978246325d96e53c 480 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 14 471 1.6E-192 T 29-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 THSYN_RS06920 20d673d1ded14c36978246325d96e53c 480 Pfam PF01458 Uncharacterized protein family (UPF0051) 218 451 1.2E-69 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 THSYN_RS20520 4968bf713cfe82724dfec852112e44ab 514 Pfam PF09820 Predicted AAA-ATPase 7 270 1.7E-90 T 29-03-2018 IPR018631 AAA-ATPase-like domain THSYN_RS20520 4968bf713cfe82724dfec852112e44ab 514 Gene3D G3DSA:3.40.50.300 25 182 6.9E-4 T 29-03-2018 THSYN_RS20520 4968bf713cfe82724dfec852112e44ab 514 Pfam PF08011 PD-(D/E)XK nuclease superfamily 416 507 8.7E-22 T 29-03-2018 IPR012547 PD-(D/E)XK nuclease superfamily 9 THSYN_RS21285 a41208a11f7b56d81227146e6c258d30 354 SUPERFAMILY SSF52540 45 188 2.67E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21285 a41208a11f7b56d81227146e6c258d30 354 Gene3D G3DSA:3.40.50.300 37 323 2.0E-9 T 29-03-2018 THSYN_RS21285 a41208a11f7b56d81227146e6c258d30 354 Pfam PF03969 AFG1-like ATPase 7 349 2.3E-119 T 29-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 THSYN_RS29495 d7f8ccab90ada6fb35f8d6e3a5f6c9f1 553 Gene3D G3DSA:3.30.70.270 379 550 2.3E-57 T 29-03-2018 THSYN_RS29495 d7f8ccab90ada6fb35f8d6e3a5f6c9f1 553 SUPERFAMILY SSF55073 386 542 1.26E-48 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS29495 d7f8ccab90ada6fb35f8d6e3a5f6c9f1 553 Pfam PF13185 GAF domain 226 369 5.2E-26 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS29495 d7f8ccab90ada6fb35f8d6e3a5f6c9f1 553 SUPERFAMILY SSF55781 25 176 1.83E-9 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS29495 d7f8ccab90ada6fb35f8d6e3a5f6c9f1 553 SMART SM00065 22 175 2.0E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS29495 d7f8ccab90ada6fb35f8d6e3a5f6c9f1 553 SMART SM00065 227 378 8.6E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS29495 d7f8ccab90ada6fb35f8d6e3a5f6c9f1 553 Gene3D G3DSA:3.30.450.40 9 206 2.7E-13 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS29495 d7f8ccab90ada6fb35f8d6e3a5f6c9f1 553 Gene3D G3DSA:3.30.450.40 207 378 2.1E-17 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS29495 d7f8ccab90ada6fb35f8d6e3a5f6c9f1 553 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 377 540 1.1E-48 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS29495 d7f8ccab90ada6fb35f8d6e3a5f6c9f1 553 SMART SM00267 370 542 1.1E-63 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS29495 d7f8ccab90ada6fb35f8d6e3a5f6c9f1 553 SUPERFAMILY SSF55781 229 381 2.62E-17 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS29495 d7f8ccab90ada6fb35f8d6e3a5f6c9f1 553 Pfam PF00990 Diguanylate cyclase, GGDEF domain 381 537 9.9E-43 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS02010 b051b14757ef992dae42a309cd2429d9 157 Gene3D G3DSA:1.20.120.520 2 151 7.7E-9 T 29-03-2018 THSYN_RS02010 b051b14757ef992dae42a309cd2429d9 157 Pfam PF01814 Hemerythrin HHE cation binding domain 4 135 7.6E-8 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THSYN_RS07965 de0849518d44e5ba664510ac60f11afe 189 Pfam PF05685 Putative restriction endonuclease 17 170 1.6E-29 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS07965 de0849518d44e5ba664510ac60f11afe 189 SUPERFAMILY SSF52980 11 169 3.06E-19 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS07965 de0849518d44e5ba664510ac60f11afe 189 Gene3D G3DSA:3.90.1570.10 4 189 2.8E-29 T 29-03-2018 THSYN_RS32435 e998543ee95f6e5e7c61215e3b0782e6 488 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 231 1.4E-21 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THSYN_RS32435 e998543ee95f6e5e7c61215e3b0782e6 488 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 485 215.914 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 THSYN_RS32435 e998543ee95f6e5e7c61215e3b0782e6 488 Gene3D G3DSA:3.40.50.300 1 242 3.2E-54 T 29-03-2018 THSYN_RS32435 e998543ee95f6e5e7c61215e3b0782e6 488 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 6 476 2.5E-147 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 THSYN_RS32435 e998543ee95f6e5e7c61215e3b0782e6 488 Gene3D G3DSA:3.40.50.880 251 478 1.1E-23 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS32435 e998543ee95f6e5e7c61215e3b0782e6 488 SUPERFAMILY SSF52540 1 239 3.32E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS32435 e998543ee95f6e5e7c61215e3b0782e6 488 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 252 435 2.9E-56 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 THSYN_RS32435 e998543ee95f6e5e7c61215e3b0782e6 488 SUPERFAMILY SSF52317 253 444 5.04E-41 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS01485 dc396b944e410bd3f354a110753bf331 611 Pfam PF00437 Type II/IV secretion system protein 237 498 5.1E-75 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THSYN_RS01485 dc396b944e410bd3f354a110753bf331 611 Gene3D G3DSA:3.30.450.90 208 331 1.8E-43 T 29-03-2018 THSYN_RS01485 dc396b944e410bd3f354a110753bf331 611 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 426 440 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THSYN_RS01485 dc396b944e410bd3f354a110753bf331 611 SUPERFAMILY SSF160246 83 182 3.66E-10 T 29-03-2018 THSYN_RS01485 dc396b944e410bd3f354a110753bf331 611 SMART SM00382 359 480 0.0035 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS01485 dc396b944e410bd3f354a110753bf331 611 SUPERFAMILY SSF52540 221 605 2.37E-92 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS01485 dc396b944e410bd3f354a110753bf331 611 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 84 183 9.8E-9 T 29-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 THSYN_RS01485 dc396b944e410bd3f354a110753bf331 611 Gene3D G3DSA:3.40.50.300 335 611 6.6E-55 T 29-03-2018 THSYN_RS23445 da73acf1cb504f6140a225df02209f32 431 SUPERFAMILY SSF56601 85 326 2.23E-81 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS23445 da73acf1cb504f6140a225df02209f32 431 Gene3D G3DSA:3.40.710.10 39 338 1.3E-60 T 29-03-2018 THSYN_RS23445 da73acf1cb504f6140a225df02209f32 431 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 166 183 1.4E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THSYN_RS23445 da73acf1cb504f6140a225df02209f32 431 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 193 206 1.4E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THSYN_RS23445 da73acf1cb504f6140a225df02209f32 431 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 113 124 1.4E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THSYN_RS23445 da73acf1cb504f6140a225df02209f32 431 SMART SM00936 326 416 6.5E-29 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS23445 da73acf1cb504f6140a225df02209f32 431 Gene3D G3DSA:2.60.410.10 339 416 1.3E-17 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS23445 da73acf1cb504f6140a225df02209f32 431 SUPERFAMILY SSF69189 326 418 1.57E-20 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS23445 da73acf1cb504f6140a225df02209f32 431 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 80 306 4.3E-80 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 THSYN_RS23445 da73acf1cb504f6140a225df02209f32 431 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 326 415 4.0E-19 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS05075 69e4126c6726413ae6e6ddfea837bd21 335 SUPERFAMILY SSF53850 27 332 4.56E-85 T 29-03-2018 THSYN_RS05075 69e4126c6726413ae6e6ddfea837bd21 335 Gene3D G3DSA:3.40.190.10 258 334 2.0E-21 T 29-03-2018 THSYN_RS05075 69e4126c6726413ae6e6ddfea837bd21 335 Gene3D G3DSA:3.40.190.10 132 257 1.2E-25 T 29-03-2018 THSYN_RS05075 69e4126c6726413ae6e6ddfea837bd21 335 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 27 331 1.7E-145 T 29-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 THSYN_RS05075 69e4126c6726413ae6e6ddfea837bd21 335 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 151 159 - T 29-03-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 THSYN_RS05075 69e4126c6726413ae6e6ddfea837bd21 335 Pfam PF13531 Bacterial extracellular solute-binding protein 42 286 3.4E-44 T 29-03-2018 THSYN_RS05075 69e4126c6726413ae6e6ddfea837bd21 335 Gene3D G3DSA:3.40.190.10 26 131 5.0E-24 T 29-03-2018 THSYN_RS03805 52bdb45b49f9bade81ad10a8c03a263a 291 Hamap MF_01384 Urease accessory protein UreD [ureD]. 13 275 30.185 T 29-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 THSYN_RS03805 52bdb45b49f9bade81ad10a8c03a263a 291 Pfam PF01774 UreD urease accessory protein 54 265 7.5E-46 T 29-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 THSYN_RS13470 546749e24ddc8153fe0183e9c61e8179 441 Gene3D G3DSA:3.30.200.20 108 247 2.0E-21 T 29-03-2018 THSYN_RS13470 546749e24ddc8153fe0183e9c61e8179 441 Pfam PF03109 ABC1 family 119 234 2.7E-28 T 29-03-2018 IPR004147 UbiB domain THSYN_RS13470 546749e24ddc8153fe0183e9c61e8179 441 SUPERFAMILY SSF56112 102 164 3.32E-17 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS13470 546749e24ddc8153fe0183e9c61e8179 441 SUPERFAMILY SSF56112 202 315 3.32E-17 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS00380 d24b8b04cd3dc6efbdca620ab276a8c7 94 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 13 87 4.4E-7 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS11825 2d9751342f6e41378010e7823d0692f9 248 Gene3D G3DSA:3.30.1950.10 73 133 3.1E-13 T 29-03-2018 THSYN_RS11825 2d9751342f6e41378010e7823d0692f9 248 Pfam PF10531 SLBB domain 145 199 2.5E-7 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS11825 2d9751342f6e41378010e7823d0692f9 248 Pfam PF02563 Polysaccharide biosynthesis/export protein 64 138 2.8E-18 T 29-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 THSYN_RS11825 2d9751342f6e41378010e7823d0692f9 248 Gene3D G3DSA:3.10.560.10 134 226 1.2E-19 T 29-03-2018 THSYN_RS28080 0430e6aad7d9a81e7a43f1bf9e94c00a 575 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 183 208 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 THSYN_RS28080 0430e6aad7d9a81e7a43f1bf9e94c00a 575 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 68 484 3.5E-61 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THSYN_RS28080 0430e6aad7d9a81e7a43f1bf9e94c00a 575 Pfam PF00474 Sodium:solute symporter family 68 484 8.6E-112 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THSYN_RS25000 ea0c49a03d47ed7acb7ad3c121239984 366 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 32 356 2.9E-93 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 THSYN_RS25000 ea0c49a03d47ed7acb7ad3c121239984 366 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 355 7.3E-86 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 THSYN_RS25000 ea0c49a03d47ed7acb7ad3c121239984 366 Gene3D G3DSA:3.40.50.2000 1 205 1.7E-72 T 29-03-2018 THSYN_RS25000 ea0c49a03d47ed7acb7ad3c121239984 366 SUPERFAMILY SSF53756 3 360 5.76E-100 T 29-03-2018 THSYN_RS25000 ea0c49a03d47ed7acb7ad3c121239984 366 Gene3D G3DSA:3.40.50.2000 206 337 2.9E-29 T 29-03-2018 THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 Gene3D G3DSA:1.25.40.20 156 325 5.0E-15 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 Gene3D G3DSA:1.25.40.20 330 457 4.5E-16 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 SMART SM00248 377 405 13.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 SMART SM00248 203 234 2200.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 SMART SM00248 344 373 0.046 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 SMART SM00248 72 101 0.11 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 SMART SM00248 170 199 190.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 SMART SM00248 39 68 0.2 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 SMART SM00248 285 314 6.1 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 Gene3D G3DSA:1.25.40.20 9 116 1.4E-20 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 Pfam PF12796 Ankyrin repeats (3 copies) 301 401 7.5E-7 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 Pfam PF12796 Ankyrin repeats (3 copies) 15 103 1.0E-11 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 PRINTS PR01415 Ankyrin repeat signature 40 55 1.2E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 PRINTS PR01415 Ankyrin repeat signature 360 374 1.2E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 SUPERFAMILY SSF48403 11 104 8.08E-18 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 SUPERFAMILY SSF48403 170 232 2.61E-24 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS29380 773606f09a2423be8e0154ab60a22323 493 SUPERFAMILY SSF48403 282 402 2.61E-24 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS05215 34f364ef476af8c201b428464cf9721a 264 Pfam PF03781 Sulfatase-modifying factor enzyme 1 26 252 3.1E-56 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS05215 34f364ef476af8c201b428464cf9721a 264 SUPERFAMILY SSF56436 25 253 3.77E-70 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS05215 34f364ef476af8c201b428464cf9721a 264 Gene3D G3DSA:3.90.1580.10 15 264 8.4E-67 T 29-03-2018 THSYN_RS11110 278a888f12f56a3bc1abd8ea40ac32a4 312 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 124 296 1.5E-15 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS11110 278a888f12f56a3bc1abd8ea40ac32a4 312 Gene3D G3DSA:3.40.190.10 201 299 1.7E-8 T 29-03-2018 THSYN_RS11110 278a888f12f56a3bc1abd8ea40ac32a4 312 Gene3D G3DSA:3.40.190.10 37 191 1.8E-15 T 29-03-2018 THSYN_RS11110 278a888f12f56a3bc1abd8ea40ac32a4 312 SUPERFAMILY SSF53850 27 297 4.67E-33 T 29-03-2018 THSYN_RS11110 278a888f12f56a3bc1abd8ea40ac32a4 312 SMART SM00062 63 300 1.7E-7 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS01390 b880473122ac931fb5ee5c834d413e9d 163 ProDom PD008308 HUPJ HYDROGENASE EXPRESSION/FORMATION HYDROGENASE-2 HYBE COMPONENT OPERON ELECTRON METAL-BINDING IRON 13 111 3.0E-19 T 29-03-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE THSYN_RS01390 b880473122ac931fb5ee5c834d413e9d 163 Pfam PF11939 [NiFe]-hydrogenase assembly, chaperone, HybE 10 156 1.8E-49 T 29-03-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE THSYN_RS01390 b880473122ac931fb5ee5c834d413e9d 163 TIGRFAM TIGR03993 hydrog_HybE: [NiFe] hydrogenase assembly chaperone, HybE family 13 156 2.3E-42 T 29-03-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE THSYN_RS28775 45bf326e8756f00e637e0d4c83dd8946 284 Pfam PF15916 Domain of unknown function (DUF4743) 4 116 1.6E-20 T 29-03-2018 IPR031804 Domain of unknown function DUF4743 THSYN_RS28775 45bf326e8756f00e637e0d4c83dd8946 284 SUPERFAMILY SSF55811 104 261 3.19E-15 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 THSYN_RS28775 45bf326e8756f00e637e0d4c83dd8946 284 Gene3D G3DSA:3.90.79.10 100 281 6.8E-23 T 29-03-2018 THSYN_RS33100 ce2100a0dd104619bbf1471106b6bbf2 52 Pfam PF11848 Domain of unknown function (DUF3368) 5 50 1.7E-13 T 29-03-2018 IPR021799 Protein of unknown function DUF3368 THSYN_RS06995 7149abda6e5c7c7c6858409bc5386bf2 221 Pfam PF01022 Bacterial regulatory protein, arsR family 26 68 3.2E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS06995 7149abda6e5c7c7c6858409bc5386bf2 221 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 5.7E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS06995 7149abda6e5c7c7c6858409bc5386bf2 221 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 5.7E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS06995 7149abda6e5c7c7c6858409bc5386bf2 221 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 19 34 5.7E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS06995 7149abda6e5c7c7c6858409bc5386bf2 221 SUPERFAMILY SSF46785 7 93 1.57E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS06995 7149abda6e5c7c7c6858409bc5386bf2 221 Gene3D G3DSA:1.10.10.10 2 92 2.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS06995 7149abda6e5c7c7c6858409bc5386bf2 221 SUPERFAMILY SSF52821 108 220 6.68E-29 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS06995 7149abda6e5c7c7c6858409bc5386bf2 221 Pfam PF00581 Rhodanese-like domain 129 213 1.2E-12 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS06995 7149abda6e5c7c7c6858409bc5386bf2 221 SMART SM00418 17 95 6.5E-24 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THSYN_RS06995 7149abda6e5c7c7c6858409bc5386bf2 221 Gene3D G3DSA:3.40.250.10 93 221 7.1E-25 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS06995 7149abda6e5c7c7c6858409bc5386bf2 221 SMART SM00450 121 217 3.0E-21 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS23425 876cceabafce56de59cb10d191879197 235 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 97 220 8.8E-39 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 THSYN_RS23425 876cceabafce56de59cb10d191879197 235 Hamap MF_00509 Cell division protein ZipA [zipA]. 4 224 17.33 T 29-03-2018 IPR011919 Cell division protein ZipA GO:0007049|GO:0016021|GO:0090529 THSYN_RS23425 876cceabafce56de59cb10d191879197 235 SUPERFAMILY SSF64383 97 227 2.22E-32 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 THSYN_RS23425 876cceabafce56de59cb10d191879197 235 Gene3D G3DSA:3.30.1400.10 96 224 1.1E-36 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 THSYN_RS23425 876cceabafce56de59cb10d191879197 235 SMART SM00771 93 222 7.5E-31 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 THSYN_RS23425 876cceabafce56de59cb10d191879197 235 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 96 222 2.0E-18 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 THSYN_RS10010 622483fc586f25a37ede2467bf5d1e38 525 Pfam PF07728 AAA domain (dynein-related subfamily) 275 422 2.1E-10 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THSYN_RS10010 622483fc586f25a37ede2467bf5d1e38 525 Gene3D G3DSA:3.40.50.300 258 464 5.0E-21 T 29-03-2018 THSYN_RS10010 622483fc586f25a37ede2467bf5d1e38 525 SUPERFAMILY SSF52540 262 439 7.72E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10010 622483fc586f25a37ede2467bf5d1e38 525 SMART SM00382 272 434 5.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS09460 d0f09712a08996cd10bc373a89dde478 209 Pfam PF10263 SprT-like family 53 131 2.1E-13 T 29-03-2018 IPR006640 SprT-like THSYN_RS09460 d0f09712a08996cd10bc373a89dde478 209 SMART SM00731 29 187 8.7E-19 T 29-03-2018 IPR006640 SprT-like THSYN_RS09460 d0f09712a08996cd10bc373a89dde478 209 Pfam PF17283 SprT-like zinc ribbon domain 149 185 2.2E-7 T 29-03-2018 IPR035240 SprT-like, zinc ribbon domain THSYN_RS22510 d3fc50cb3e8119a82263f61a2acd600b 222 SUPERFAMILY SSF56784 4 214 1.2E-57 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS22510 d3fc50cb3e8119a82263f61a2acd600b 222 Gene3D G3DSA:3.40.50.1000 74 219 8.6E-34 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS22510 d3fc50cb3e8119a82263f61a2acd600b 222 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 88 178 8.5E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS22510 d3fc50cb3e8119a82263f61a2acd600b 222 Gene3D G3DSA:1.10.150.240 21 73 6.2E-16 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 THSYN_RS22510 d3fc50cb3e8119a82263f61a2acd600b 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 61 181 1.0E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS22510 d3fc50cb3e8119a82263f61a2acd600b 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 184 1.5E-31 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS24805 19792ab8200cbca08d37bc5a84af4ff3 600 ProSitePatterns PS00211 ABC transporters family signature. 485 499 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS24805 19792ab8200cbca08d37bc5a84af4ff3 600 Pfam PF00005 ABC transporter 365 513 1.6E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS24805 19792ab8200cbca08d37bc5a84af4ff3 600 SUPERFAMILY SSF90123 19 331 5.76E-75 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS24805 19792ab8200cbca08d37bc5a84af4ff3 600 Pfam PF00664 ABC transporter transmembrane region 33 299 9.5E-54 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS24805 19792ab8200cbca08d37bc5a84af4ff3 600 Gene3D G3DSA:3.40.50.300 343 580 2.4E-71 T 29-03-2018 THSYN_RS24805 19792ab8200cbca08d37bc5a84af4ff3 600 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 17 586 1.2E-236 T 29-03-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 THSYN_RS24805 19792ab8200cbca08d37bc5a84af4ff3 600 SUPERFAMILY SSF52540 337 584 2.17E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24805 19792ab8200cbca08d37bc5a84af4ff3 600 SMART SM00382 372 559 1.1E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS24805 19792ab8200cbca08d37bc5a84af4ff3 600 Gene3D G3DSA:1.20.1560.10 11 334 4.2E-64 T 29-03-2018 THSYN_RS31260 8ee2f818406c537f25c6f0b6c42abec6 80 Gene3D G3DSA:4.10.220.20 20 63 8.0E-15 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31260 8ee2f818406c537f25c6f0b6c42abec6 80 SUPERFAMILY SSF56918 16 67 4.66E-8 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS04020 693db42559e0d13d588509452cb3e25e 92 SUPERFAMILY SSF54862 6 61 1.13E-13 T 29-03-2018 THSYN_RS04020 693db42559e0d13d588509452cb3e25e 92 Gene3D G3DSA:3.30.70.20 25 65 0.002 T 29-03-2018 THSYN_RS04020 693db42559e0d13d588509452cb3e25e 92 Gene3D G3DSA:3.30.70.20 4 24 0.0088 T 29-03-2018 THSYN_RS04020 693db42559e0d13d588509452cb3e25e 92 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS11395 78f4eba2c30fae8fa1a06dd62323bc4e 331 Gene3D G3DSA:3.40.630.30 25 181 7.8E-14 T 29-03-2018 THSYN_RS11395 78f4eba2c30fae8fa1a06dd62323bc4e 331 Pfam PF00583 Acetyltransferase (GNAT) family 96 177 9.8E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS11395 78f4eba2c30fae8fa1a06dd62323bc4e 331 SUPERFAMILY SSF55729 54 180 1.77E-16 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS07405 f73ef4e8cb2a318e676800c58d572f3d 219 Gene3D G3DSA:1.10.340.30 22 117 8.4E-24 T 29-03-2018 THSYN_RS07405 f73ef4e8cb2a318e676800c58d572f3d 219 PIRSF PIRSF001435 1 212 2.7E-48 T 29-03-2018 THSYN_RS07405 f73ef4e8cb2a318e676800c58d572f3d 219 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 166 4.6E-19 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THSYN_RS07405 f73ef4e8cb2a318e676800c58d572f3d 219 Pfam PF00633 Helix-hairpin-helix motif 100 127 1.2E-7 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 THSYN_RS07405 f73ef4e8cb2a318e676800c58d572f3d 219 Gene3D G3DSA:1.10.1670.10 118 219 2.2E-30 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 THSYN_RS07405 f73ef4e8cb2a318e676800c58d572f3d 219 Hamap MF_00942 Endonuclease III [nth]. 1 209 36.802 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 THSYN_RS07405 f73ef4e8cb2a318e676800c58d572f3d 219 SUPERFAMILY SSF48150 2 210 2.04E-71 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 THSYN_RS07405 f73ef4e8cb2a318e676800c58d572f3d 219 SMART SM00525 186 206 0.0055 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 THSYN_RS07405 f73ef4e8cb2a318e676800c58d572f3d 219 TIGRFAM TIGR01083 nth: endonuclease III 5 194 8.5E-82 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 THSYN_RS07405 f73ef4e8cb2a318e676800c58d572f3d 219 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 THSYN_RS07405 f73ef4e8cb2a318e676800c58d572f3d 219 SMART SM00478 38 185 3.6E-53 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THSYN_RS03025 ee115d89530dba4bd6e33289aaedc4bb 300 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 75 291 6.1E-7 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THSYN_RS03025 ee115d89530dba4bd6e33289aaedc4bb 300 PIRSF PIRSF028561 1 300 2.1E-106 T 29-03-2018 IPR014548 Predicted acyltransferase THSYN_RS28910 e3633b8455519b5883038d5c3706abdb 179 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THSYN_RS28910 e3633b8455519b5883038d5c3706abdb 179 Pfam PF00293 NUDIX domain 7 145 4.4E-23 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THSYN_RS28910 e3633b8455519b5883038d5c3706abdb 179 PRINTS PR00502 NUDIX hydrolase family signature 33 47 2.4E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THSYN_RS28910 e3633b8455519b5883038d5c3706abdb 179 PRINTS PR00502 NUDIX hydrolase family signature 47 62 2.4E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THSYN_RS28910 e3633b8455519b5883038d5c3706abdb 179 Gene3D G3DSA:3.90.79.10 1 159 2.4E-29 T 29-03-2018 THSYN_RS28910 e3633b8455519b5883038d5c3706abdb 179 SUPERFAMILY SSF55811 6 157 2.98E-29 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 THSYN_RS28910 e3633b8455519b5883038d5c3706abdb 179 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 35.575 T 29-03-2018 IPR022927 RNA pyrophosphohydrolase RppH THSYN_RS15380 1368595fc175abf6a66b68eefc876b99 199 SUPERFAMILY SSF51306 76 196 1.59E-26 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THSYN_RS15380 1368595fc175abf6a66b68eefc876b99 199 TIGRFAM TIGR00498 lexA: repressor LexA 2 197 5.1E-43 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 THSYN_RS15380 1368595fc175abf6a66b68eefc876b99 199 Pfam PF00717 Peptidase S24-like 114 180 2.1E-14 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THSYN_RS15380 1368595fc175abf6a66b68eefc876b99 199 Pfam PF01726 LexA DNA binding domain 2 57 8.4E-9 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 THSYN_RS15380 1368595fc175abf6a66b68eefc876b99 199 Gene3D G3DSA:1.10.10.10 1 67 2.8E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS15380 1368595fc175abf6a66b68eefc876b99 199 Hamap MF_00015 LexA repressor [lexA]. 2 198 27.406 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 THSYN_RS15380 1368595fc175abf6a66b68eefc876b99 199 Gene3D G3DSA:2.10.109.10 81 198 1.1E-21 T 29-03-2018 THSYN_RS15380 1368595fc175abf6a66b68eefc876b99 199 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 111 121 1.2E-7 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THSYN_RS15380 1368595fc175abf6a66b68eefc876b99 199 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 151 163 1.2E-7 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THSYN_RS15380 1368595fc175abf6a66b68eefc876b99 199 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 122 133 1.2E-7 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THSYN_RS15380 1368595fc175abf6a66b68eefc876b99 199 SUPERFAMILY SSF46785 1 68 1.25E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS00215 5fc3e12c1215f26a7bb12ed9a6fbdaab 296 Gene3D G3DSA:1.20.144.10 2 230 1.0E-20 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS00215 5fc3e12c1215f26a7bb12ed9a6fbdaab 296 Pfam PF01569 PAP2 superfamily 101 217 3.5E-19 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS00215 5fc3e12c1215f26a7bb12ed9a6fbdaab 296 SMART SM00014 100 216 9.3E-11 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS00215 5fc3e12c1215f26a7bb12ed9a6fbdaab 296 SUPERFAMILY SSF48317 38 221 9.42E-26 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS21655 f5dc15add1e1b81f285ed77633e06f19 710 Pfam PF00128 Alpha amylase, catalytic domain 180 280 9.3E-9 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THSYN_RS21655 f5dc15add1e1b81f285ed77633e06f19 710 Gene3D G3DSA:3.20.20.80 150 585 6.7E-113 T 29-03-2018 THSYN_RS21655 f5dc15add1e1b81f285ed77633e06f19 710 Gene3D G3DSA:2.60.40.1180 586 697 6.8E-21 T 29-03-2018 THSYN_RS21655 f5dc15add1e1b81f285ed77633e06f19 710 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 13 693 1.0E-205 T 29-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 THSYN_RS21655 f5dc15add1e1b81f285ed77633e06f19 710 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 19 110 5.5E-11 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 THSYN_RS21655 f5dc15add1e1b81f285ed77633e06f19 710 SUPERFAMILY SSF51445 505 581 1.28E-129 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS21655 f5dc15add1e1b81f285ed77633e06f19 710 SUPERFAMILY SSF51445 137 476 1.28E-129 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS21655 f5dc15add1e1b81f285ed77633e06f19 710 SUPERFAMILY SSF81296 12 149 5.04E-26 T 29-03-2018 IPR014756 Immunoglobulin E-set THSYN_RS21655 f5dc15add1e1b81f285ed77633e06f19 710 SMART SM00642 162 573 1.1E-9 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THSYN_RS21655 f5dc15add1e1b81f285ed77633e06f19 710 Gene3D G3DSA:2.60.40.10 1 149 3.9E-24 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS21655 f5dc15add1e1b81f285ed77633e06f19 710 SUPERFAMILY SSF51011 594 695 9.35E-17 T 29-03-2018 THSYN_RS17835 14e0915773f67b5e2e065632383b522f 86 SUPERFAMILY SSF143011 5 76 1.44E-8 T 29-03-2018 IPR035095 Toxin RelE-like domain THSYN_RS17835 14e0915773f67b5e2e065632383b522f 86 Gene3D G3DSA:3.30.2310.20 1 79 5.6E-9 T 29-03-2018 THSYN_RS31640 85e9d47963d119206589e5852d5b8ec2 452 SUPERFAMILY SSF102114 46 433 6.28E-104 T 29-03-2018 THSYN_RS31640 85e9d47963d119206589e5852d5b8ec2 452 Pfam PF04055 Radical SAM superfamily 60 232 2.4E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS31640 85e9d47963d119206589e5852d5b8ec2 452 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 12 434 4.0E-110 T 29-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 THSYN_RS31640 85e9d47963d119206589e5852d5b8ec2 452 SMART SM00729 55 276 5.5E-46 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS31640 85e9d47963d119206589e5852d5b8ec2 452 Gene3D G3DSA:3.20.20.70 34 385 6.0E-37 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS31640 85e9d47963d119206589e5852d5b8ec2 452 PIRSF PIRSF000167 29 445 1.5E-122 T 29-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 THSYN_RS27615 d9aab8fcbdcf036c02d320f1735a2c96 932 Gene3D G3DSA:3.40.50.300 76 352 2.0E-5 T 29-03-2018 THSYN_RS27615 d9aab8fcbdcf036c02d320f1735a2c96 932 Gene3D G3DSA:3.90.1580.10 668 932 1.2E-51 T 29-03-2018 THSYN_RS27615 d9aab8fcbdcf036c02d320f1735a2c96 932 SUPERFAMILY SSF56436 683 926 6.83E-58 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS27615 d9aab8fcbdcf036c02d320f1735a2c96 932 SUPERFAMILY SSF52540 144 171 7.83E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27615 d9aab8fcbdcf036c02d320f1735a2c96 932 SUPERFAMILY SSF52540 281 347 7.83E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27615 d9aab8fcbdcf036c02d320f1735a2c96 932 Pfam PF03781 Sulfatase-modifying factor enzyme 1 716 925 7.4E-48 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS27615 d9aab8fcbdcf036c02d320f1735a2c96 932 SMART SM00382 143 346 0.0017 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS09785 efa99f113034b373575ec5a1e4faa274 297 PRINTS PR00412 Epoxide hydrolase signature 94 107 2.2E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS09785 efa99f113034b373575ec5a1e4faa274 297 PRINTS PR00412 Epoxide hydrolase signature 231 247 2.2E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS09785 efa99f113034b373575ec5a1e4faa274 297 PRINTS PR00412 Epoxide hydrolase signature 264 286 2.2E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS09785 efa99f113034b373575ec5a1e4faa274 297 PRINTS PR00412 Epoxide hydrolase signature 108 121 2.2E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS09785 efa99f113034b373575ec5a1e4faa274 297 PRINTS PR00412 Epoxide hydrolase signature 31 49 2.2E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS09785 efa99f113034b373575ec5a1e4faa274 297 SUPERFAMILY SSF53474 7 127 1.46E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS09785 efa99f113034b373575ec5a1e4faa274 297 SUPERFAMILY SSF53474 172 288 1.46E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS09785 efa99f113034b373575ec5a1e4faa274 297 Gene3D G3DSA:3.40.50.1820 6 289 1.5E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS09785 efa99f113034b373575ec5a1e4faa274 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 6.6E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS09785 efa99f113034b373575ec5a1e4faa274 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 6.6E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS09785 efa99f113034b373575ec5a1e4faa274 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 6.6E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS09785 efa99f113034b373575ec5a1e4faa274 297 Pfam PF12697 Alpha/beta hydrolase family 27 279 9.4E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS26790 a41f0cea9a892764e1468cf6434e405a 666 Gene3D G3DSA:1.25.40.10 426 664 7.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS26790 a41f0cea9a892764e1468cf6434e405a 666 Gene3D G3DSA:1.10.287.70 12 271 0.0026 T 29-03-2018 THSYN_RS23835 0e3e8bb6203dadab7c19f5b5747f95bd 118 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 118 1.0E-39 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23835 0e3e8bb6203dadab7c19f5b5747f95bd 118 Gene3D G3DSA:3.30.420.100 1 118 2.9E-39 T 29-03-2018 THSYN_RS23835 0e3e8bb6203dadab7c19f5b5747f95bd 118 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 118 26.399 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23835 0e3e8bb6203dadab7c19f5b5747f95bd 118 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 118 8.6E-40 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23835 0e3e8bb6203dadab7c19f5b5747f95bd 118 SUPERFAMILY SSF53137 3 116 3.49E-53 T 29-03-2018 THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 Gene3D G3DSA:3.40.50.300 324 520 5.0E-12 T 29-03-2018 THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 Pfam PF12770 CHAT domain 43 281 3.6E-16 T 29-03-2018 IPR024983 CHAT domain THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 Gene3D G3DSA:1.10.150.200 974 1023 2.2E-7 T 29-03-2018 THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 Gene3D G3DSA:1.10.150.200 1024 1078 2.3E-6 T 29-03-2018 THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 Gene3D G3DSA:1.25.40.10 804 923 7.3E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 SUPERFAMILY SSF48452 935 1090 5.69E-21 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 SUPERFAMILY SSF52540 331 472 2.43E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 SUPERFAMILY SSF52540 505 633 2.43E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 Gene3D G3DSA:3.30.70.100 924 973 0.0032 T 29-03-2018 THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 SUPERFAMILY SSF48452 846 967 1.61E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 Pfam PF13424 Tetratricopeptide repeat 944 1008 1.9E-9 T 29-03-2018 THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 Gene3D G3DSA:3.40.50.1460 4 296 3.2E-21 T 29-03-2018 THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 SMART SM00028 978 1011 3.5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 SMART SM00028 938 971 78.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS28050 77ceaae6ee91e54dc51f00977129a924 1221 SMART SM00028 898 931 240.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS26520 5f7c6f7893fc30cc5d7c5dbd567ccce3 183 Gene3D G3DSA:1.50.10.10 31 131 4.3E-4 T 29-03-2018 THSYN_RS26520 5f7c6f7893fc30cc5d7c5dbd567ccce3 183 Pfam PF13471 Transglutaminase-like superfamily 28 144 8.0E-25 T 29-03-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal THSYN_RS14525 91d30970b73fdc92d66b3ab69e129605 259 SMART SM00471 72 209 3.1E-5 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS14525 91d30970b73fdc92d66b3ab69e129605 259 SUPERFAMILY SSF52172 6 54 7.12E-7 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS14525 91d30970b73fdc92d66b3ab69e129605 259 Gene3D G3DSA:1.10.3210.10 63 258 1.0E-36 T 29-03-2018 THSYN_RS14525 91d30970b73fdc92d66b3ab69e129605 259 SUPERFAMILY SSF109604 66 240 1.35E-33 T 29-03-2018 THSYN_RS14525 91d30970b73fdc92d66b3ab69e129605 259 Gene3D G3DSA:3.40.50.2300 4 62 1.3E-4 T 29-03-2018 THSYN_RS14525 91d30970b73fdc92d66b3ab69e129605 259 Pfam PF01966 HD domain 77 199 8.2E-17 T 29-03-2018 IPR006674 HD domain THSYN_RS14650 f3c8ad83b96eeb5d29c418ee06bc79a5 574 Pfam PF04055 Radical SAM superfamily 320 482 2.3E-8 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS14650 f3c8ad83b96eeb5d29c418ee06bc79a5 574 SUPERFAMILY SSF102114 290 511 4.32E-25 T 29-03-2018 THSYN_RS14650 f3c8ad83b96eeb5d29c418ee06bc79a5 574 Pfam PF02310 B12 binding domain 174 258 3.5E-7 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 THSYN_RS14650 f3c8ad83b96eeb5d29c418ee06bc79a5 574 SMART SM00729 314 517 1.3E-12 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS14650 f3c8ad83b96eeb5d29c418ee06bc79a5 574 Gene3D G3DSA:3.40.50.280 18 263 4.6E-10 T 29-03-2018 THSYN_RS14650 f3c8ad83b96eeb5d29c418ee06bc79a5 574 Gene3D G3DSA:3.20.20.70 273 558 8.0E-17 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS27770 5a6f5c8856318718ff86f9b7fdebb914 327 SUPERFAMILY SSF53807 47 323 4.91E-76 T 29-03-2018 THSYN_RS27770 5a6f5c8856318718ff86f9b7fdebb914 327 Pfam PF01297 Zinc-uptake complex component A periplasmic 50 315 4.6E-57 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 THSYN_RS27770 5a6f5c8856318718ff86f9b7fdebb914 327 Gene3D G3DSA:3.40.50.1980 218 323 1.5E-23 T 29-03-2018 THSYN_RS27770 5a6f5c8856318718ff86f9b7fdebb914 327 Gene3D G3DSA:3.40.50.1980 36 217 6.0E-46 T 29-03-2018 THSYN_RS06585 9add966bc0a2e0cdcacc9d0b4954cee5 166 SMART SM01321 10 136 0.0043 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS06585 9add966bc0a2e0cdcacc9d0b4954cee5 166 SUPERFAMILY SSF143422 10 142 3.79E-18 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS06585 9add966bc0a2e0cdcacc9d0b4954cee5 166 Gene3D G3DSA:3.30.70.1290 9 142 1.9E-21 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS09710 d6628b2cb3668241a3305f542eaed1c4 127 Gene3D G3DSA:3.40.50.1010 3 118 3.7E-10 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS09710 d6628b2cb3668241a3305f542eaed1c4 127 SUPERFAMILY SSF88723 32 112 4.77E-9 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS09710 d6628b2cb3668241a3305f542eaed1c4 127 Pfam PF01850 PIN domain 49 102 4.8E-5 T 29-03-2018 IPR002716 PIN domain THSYN_RS02590 f1b308ded2cafd30e1981ec671f2006c 1303 SUPERFAMILY SSF52540 423 494 3.24E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02590 f1b308ded2cafd30e1981ec671f2006c 1303 SUPERFAMILY SSF52540 752 944 3.24E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02590 f1b308ded2cafd30e1981ec671f2006c 1303 Pfam PF00271 Helicase conserved C-terminal domain 783 890 2.2E-18 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS02590 f1b308ded2cafd30e1981ec671f2006c 1303 Pfam PF00176 SNF2 family N-terminal domain 314 499 2.3E-9 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THSYN_RS02590 f1b308ded2cafd30e1981ec671f2006c 1303 SMART SM00490 796 890 2.0E-20 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS02590 f1b308ded2cafd30e1981ec671f2006c 1303 Gene3D G3DSA:3.40.50.300 752 939 1.1E-27 T 29-03-2018 THSYN_RS02590 f1b308ded2cafd30e1981ec671f2006c 1303 SUPERFAMILY SSF52540 287 506 1.42E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02590 f1b308ded2cafd30e1981ec671f2006c 1303 SMART SM00487 290 510 3.5E-10 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS02590 f1b308ded2cafd30e1981ec671f2006c 1303 Gene3D G3DSA:3.40.50.10810 282 605 3.4E-22 T 29-03-2018 THSYN_RS10315 cabf36651734a5b6341fe4409d0079de 545 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 17 175 2.8E-15 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 THSYN_RS10315 cabf36651734a5b6341fe4409d0079de 545 PIRSF PIRSF006439 1 543 2.5E-172 T 29-03-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 THSYN_RS10315 cabf36651734a5b6341fe4409d0079de 545 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 364 511 1.5E-21 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THSYN_RS10315 cabf36651734a5b6341fe4409d0079de 545 Gene3D G3DSA:3.40.50.920 241 325 0.0034 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS10315 cabf36651734a5b6341fe4409d0079de 545 SUPERFAMILY SSF52922 228 289 3.14E-7 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS10315 cabf36651734a5b6341fe4409d0079de 545 SUPERFAMILY SSF52518 5 216 1.0E-53 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS10315 cabf36651734a5b6341fe4409d0079de 545 Gene3D G3DSA:3.40.50.970 354 525 3.0E-20 T 29-03-2018 THSYN_RS10315 cabf36651734a5b6341fe4409d0079de 545 Gene3D G3DSA:3.40.50.970 3 240 1.1E-36 T 29-03-2018 THSYN_RS10315 cabf36651734a5b6341fe4409d0079de 545 SUPERFAMILY SSF52518 337 523 1.03E-28 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS27840 924677c1d4d4e9a4cac3a516f7d28a78 1127 Gene3D G3DSA:2.60.40.10 704 802 0.034 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS27840 924677c1d4d4e9a4cac3a516f7d28a78 1127 ProSitePatterns PS00018 EF-hand calcium-binding domain. 1070 1082 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS27840 924677c1d4d4e9a4cac3a516f7d28a78 1127 ProSitePatterns PS00018 EF-hand calcium-binding domain. 1101 1113 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS27840 924677c1d4d4e9a4cac3a516f7d28a78 1127 SUPERFAMILY SSF63446 1066 1117 1.15E-5 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 THSYN_RS23000 d51b72737c21ca04e25e46a7cf72eda3 396 Pfam PF01609 Transposase DDE domain 91 329 1.7E-15 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS23000 d51b72737c21ca04e25e46a7cf72eda3 396 SUPERFAMILY SSF53098 12 364 1.67E-38 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS23000 d51b72737c21ca04e25e46a7cf72eda3 396 Gene3D G3DSA:3.90.350.10 136 309 2.3E-16 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS27080 d51b72737c21ca04e25e46a7cf72eda3 396 Pfam PF01609 Transposase DDE domain 91 329 1.7E-15 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS27080 d51b72737c21ca04e25e46a7cf72eda3 396 SUPERFAMILY SSF53098 12 364 1.67E-38 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS27080 d51b72737c21ca04e25e46a7cf72eda3 396 Gene3D G3DSA:3.90.350.10 136 309 2.3E-16 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS08440 d51b72737c21ca04e25e46a7cf72eda3 396 Pfam PF01609 Transposase DDE domain 91 329 1.7E-15 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS08440 d51b72737c21ca04e25e46a7cf72eda3 396 SUPERFAMILY SSF53098 12 364 1.67E-38 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS08440 d51b72737c21ca04e25e46a7cf72eda3 396 Gene3D G3DSA:3.90.350.10 136 309 2.3E-16 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS15225 1a04e81356814bfe80a30245c787fd8f 374 Pfam PF12698 ABC-2 family transporter protein 25 363 6.1E-28 T 29-03-2018 THSYN_RS15225 1a04e81356814bfe80a30245c787fd8f 374 Gene3D G3DSA:3.40.1710.10 40 191 5.1E-21 T 29-03-2018 THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 Gene3D G3DSA:3.30.465.10 238 417 9.1E-21 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 Pfam PF13183 4Fe-4S dicluster domain 813 892 3.5E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 Gene3D G3DSA:1.10.1060.10 788 914 1.9E-12 T 29-03-2018 THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 SUPERFAMILY SSF55103 661 780 1.78E-38 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 SUPERFAMILY SSF55103 403 530 1.78E-38 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 Pfam PF01565 FAD binding domain 169 309 2.4E-23 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 SUPERFAMILY SSF56176 131 398 7.01E-52 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 Gene3D G3DSA:3.30.43.10 116 221 1.1E-13 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 Pfam PF12447 Protein of unknown function (DUF3683) 8 119 1.0E-46 T 29-03-2018 IPR022153 Protein of unknown function DUF3683 THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 SUPERFAMILY SSF46548 794 908 2.09E-12 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 Pfam PF02754 Cysteine-rich domain 1150 1238 0.0043 T 29-03-2018 IPR004017 Cysteine-rich domain THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 Pfam PF02754 Cysteine-rich domain 1025 1113 4.4E-5 T 29-03-2018 IPR004017 Cysteine-rich domain THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 Pfam PF11880 Domain of unknown function (DUF3400) 1242 1285 6.4E-19 T 29-03-2018 IPR021817 Protein of unknown function DUF3400 THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 Pfam PF02913 FAD linked oxidases, C-terminal domain 433 547 7.3E-6 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THSYN_RS07280 8b06b804e3707b6097fe3b0a5a648480 1285 Pfam PF02913 FAD linked oxidases, C-terminal domain 678 777 9.9E-19 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THSYN_RS01180 c20c6ac28d2c58e0792941be4d2b4922 888 SUPERFAMILY SSF52518 470 697 2.0E-98 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS01180 c20c6ac28d2c58e0792941be4d2b4922 888 PIRSF PIRSF000156 1 888 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 THSYN_RS01180 c20c6ac28d2c58e0792941be4d2b4922 888 SUPERFAMILY SSF52518 55 465 1.16E-141 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS01180 c20c6ac28d2c58e0792941be4d2b4922 888 SUPERFAMILY SSF52922 703 887 1.92E-59 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS01180 c20c6ac28d2c58e0792941be4d2b4922 888 Gene3D G3DSA:3.40.50.920 707 888 7.6E-44 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS01180 c20c6ac28d2c58e0792941be4d2b4922 888 Gene3D G3DSA:3.40.50.970 54 468 8.1E-86 T 29-03-2018 THSYN_RS01180 c20c6ac28d2c58e0792941be4d2b4922 888 Gene3D G3DSA:3.40.50.970 469 702 7.8E-70 T 29-03-2018 THSYN_RS01180 c20c6ac28d2c58e0792941be4d2b4922 888 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 138 291 1.4E-8 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THSYN_RS01180 c20c6ac28d2c58e0792941be4d2b4922 888 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 4 887 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 THSYN_RS10635 cfa8df744e2714ea271cb632a6063581 428 Pfam PF10117 McrBC 5-methylcytosine restriction system component 49 373 1.6E-53 T 29-03-2018 IPR019292 5-methylcytosine restriction system component THSYN_RS24150 f5be8dad81cf533ce11e4d6d41cb508f 700 SUPERFAMILY SSF52540 544 643 1.25E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24150 f5be8dad81cf533ce11e4d6d41cb508f 700 SUPERFAMILY SSF52540 1 147 1.25E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24150 f5be8dad81cf533ce11e4d6d41cb508f 700 Pfam PF13175 AAA ATPase domain 1 44 4.2E-10 T 29-03-2018 THSYN_RS24150 f5be8dad81cf533ce11e4d6d41cb508f 700 Pfam PF13175 AAA ATPase domain 542 627 5.3E-11 T 29-03-2018 THSYN_RS24150 f5be8dad81cf533ce11e4d6d41cb508f 700 Pfam PF12476 Protein of unknown function (DUF3696) 650 692 3.1E-6 T 29-03-2018 IPR022532 Domain of unknown function DUF3696, C-terminal THSYN_RS24150 f5be8dad81cf533ce11e4d6d41cb508f 700 Gene3D G3DSA:3.40.50.300 1 645 4.7E-20 T 29-03-2018 THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 Pfam PF00512 His Kinase A (phospho-acceptor) domain 221 284 2.2E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 442 6.1E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 SUPERFAMILY SSF55874 274 442 6.81E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 442 1.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 423 1.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 400 1.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 386 1.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 SMART SM00304 165 220 3.5E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 SMART SM00387 329 445 2.2E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 Pfam PF00672 HAMP domain 165 216 1.1E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 SMART SM00388 221 284 8.0E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 SUPERFAMILY SSF158472 165 219 1.57E-7 T 29-03-2018 THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 Gene3D G3DSA:1.10.287.130 211 277 4.7E-14 T 29-03-2018 THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 Gene3D G3DSA:3.30.565.10 278 444 3.5E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS12460 e31f4596c81fa7286efafebce9098eb2 447 SUPERFAMILY SSF47384 206 284 1.29E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS31110 fdf3b43ac72487c9433fc7eb9712342b 77 SUPERFAMILY SSF57716 39 72 9.41E-7 T 29-03-2018 THSYN_RS31110 fdf3b43ac72487c9433fc7eb9712342b 77 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 37 69 1.2E-9 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 Gene3D G3DSA:3.30.450.20 523 600 0.28 T 29-03-2018 THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 401 525 2.2E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 Pfam PF00072 Response regulator receiver domain 967 1076 2.8E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 Gene3D G3DSA:3.30.450.20 386 522 3.8E-28 T 29-03-2018 THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 Pfam PF08448 PAS fold 410 521 6.6E-9 T 29-03-2018 IPR013656 PAS fold-4 THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 Gene3D G3DSA:3.40.50.2300 962 1082 6.7E-24 T 29-03-2018 THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 Gene3D G3DSA:3.30.565.10 768 939 7.2E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 SUPERFAMILY SSF55785 392 517 1.69E-21 T 29-03-2018 IPR000014 PAS domain THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 SMART SM00387 808 931 3.2E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 SMART SM00091 404 470 2.2E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 SMART SM00448 965 1076 1.5E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 PRINTS PR00344 Bacterial sensor protein C-terminal signature 891 909 2.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 PRINTS PR00344 Bacterial sensor protein C-terminal signature 915 928 2.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 PRINTS PR00344 Bacterial sensor protein C-terminal signature 860 874 2.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 PRINTS PR00344 Bacterial sensor protein C-terminal signature 878 888 2.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 813 930 7.9E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 SUPERFAMILY SSF52172 965 1080 2.85E-24 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS07750 a8285fb07aa912a533641f437cffb57c 1082 SUPERFAMILY SSF55874 767 930 3.01E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 SUPERFAMILY SSF52172 698 827 5.98E-27 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 SUPERFAMILY SSF55874 509 681 2.49E-50 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 SMART SM00387 567 683 4.7E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 Gene3D G3DSA:1.10.287.130 459 516 8.5E-22 T 29-03-2018 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 Gene3D G3DSA:3.30.450.20 50 279 0.022 T 29-03-2018 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 567 682 1.4E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 SMART SM00448 699 817 8.3E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 SMART SM00448 861 974 4.1E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 Pfam PF00512 His Kinase A (phospho-acceptor) domain 455 520 2.5E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 SUPERFAMILY SSF47384 440 521 1.59E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 Pfam PF00072 Response regulator receiver domain 702 816 1.6E-12 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 Pfam PF00072 Response regulator receiver domain 863 974 3.3E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 PRINTS PR00344 Bacterial sensor protein C-terminal signature 667 680 5.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 PRINTS PR00344 Bacterial sensor protein C-terminal signature 626 636 5.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 PRINTS PR00344 Bacterial sensor protein C-terminal signature 643 661 5.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 PRINTS PR00344 Bacterial sensor protein C-terminal signature 608 622 5.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 Gene3D G3DSA:3.40.50.2300 695 839 3.9E-27 T 29-03-2018 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 SMART SM00388 455 520 2.0E-26 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 Gene3D G3DSA:3.40.50.2300 849 982 9.4E-43 T 29-03-2018 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 SUPERFAMILY SSF55781 263 433 2.31E-15 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 Gene3D G3DSA:3.30.565.10 524 690 5.0E-52 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 Pfam PF13185 GAF domain 305 432 2.3E-11 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 SUPERFAMILY SSF52172 862 980 2.28E-37 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 Gene3D G3DSA:3.30.450.20 438 458 0.0038 T 29-03-2018 THSYN_RS08415 cd43e60df0b92ecd8ec0bcb13bd9c011 982 Gene3D G3DSA:3.30.450.40 280 437 5.1E-12 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS12665 b26c41a4a1cb8347769cea9484c96898 157 Gene3D G3DSA:1.10.10.10 20 149 4.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS21775 19bf91a5d46a1a310df1ca14b427152f 103 Gene3D G3DSA:2.60.120.10 2 102 2.6E-39 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS21775 19bf91a5d46a1a310df1ca14b427152f 103 SUPERFAMILY SSF51182 11 103 2.97E-34 T 29-03-2018 IPR011051 RmlC-like cupin domain THSYN_RS21775 19bf91a5d46a1a310df1ca14b427152f 103 Hamap MF_01537 UPF0345 protein YaiE [yaiE]. 10 103 28.402 T 29-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase THSYN_RS21775 19bf91a5d46a1a310df1ca14b427152f 103 Pfam PF06865 Protein of unknown function (DUF1255) 12 102 1.2E-36 T 29-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase THSYN_RS12170 66733a2ac499f6ff4d4992f6b00ed32c 102 Gene3D G3DSA:3.30.70.930 1 102 1.4E-38 T 29-03-2018 IPR029756 MTH1187/YkoF-like THSYN_RS12170 66733a2ac499f6ff4d4992f6b00ed32c 102 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 3 98 3.5E-30 T 29-03-2018 IPR002767 Thiamine-binding protein THSYN_RS12170 66733a2ac499f6ff4d4992f6b00ed32c 102 SUPERFAMILY SSF89957 1 98 8.37E-33 T 29-03-2018 IPR029756 MTH1187/YkoF-like THSYN_RS12170 66733a2ac499f6ff4d4992f6b00ed32c 102 Pfam PF01910 Thiamine-binding protein 5 95 1.9E-31 T 29-03-2018 IPR002767 Thiamine-binding protein THSYN_RS11480 337455f3fa1d7b885122c40065f9de91 296 SUPERFAMILY SSF54675 19 124 9.42E-24 T 29-03-2018 THSYN_RS11480 337455f3fa1d7b885122c40065f9de91 296 Gene3D G3DSA:3.90.1170.20 10 152 1.7E-29 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 THSYN_RS11480 337455f3fa1d7b885122c40065f9de91 296 Gene3D G3DSA:3.20.20.70 153 281 5.7E-22 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS11480 337455f3fa1d7b885122c40065f9de91 296 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 125 292 3.0E-25 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 THSYN_RS11480 337455f3fa1d7b885122c40065f9de91 296 SUPERFAMILY SSF51690 125 292 1.29E-33 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 THSYN_RS11480 337455f3fa1d7b885122c40065f9de91 296 PIRSF PIRSF006250 21 296 2.6E-57 T 29-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 THSYN_RS11480 337455f3fa1d7b885122c40065f9de91 296 TIGRFAM TIGR01334 modD: modD protein 23 293 3.0E-80 T 29-03-2018 IPR006242 Putative pyrophosphorylase ModD GO:0016763 THSYN_RS11480 337455f3fa1d7b885122c40065f9de91 296 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 37 123 5.8E-21 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 THSYN_RS13415 f9563b299805d24f0cdcff3fbf28b655 378 Gene3D G3DSA:3.90.1200.10 123 360 2.8E-19 T 29-03-2018 THSYN_RS13415 f9563b299805d24f0cdcff3fbf28b655 378 SUPERFAMILY SSF56112 32 350 1.75E-43 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS13415 f9563b299805d24f0cdcff3fbf28b655 378 Pfam PF01636 Phosphotransferase enzyme family 36 282 1.2E-27 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase THSYN_RS13415 f9563b299805d24f0cdcff3fbf28b655 378 Gene3D G3DSA:3.30.200.20 22 118 4.0E-15 T 29-03-2018 THSYN_RS14465 577efdd9e3bfbf3b3db92d0bc4718062 247 SUPERFAMILY SSF56235 101 203 9.36E-13 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS14465 577efdd9e3bfbf3b3db92d0bc4718062 247 Gene3D G3DSA:3.60.20.10 29 206 8.2E-11 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS09740 d89777aceadcde077f0845e6bb20c074 142 Gene3D G3DSA:2.40.50.100 65 132 1.5E-21 T 29-03-2018 THSYN_RS09740 d89777aceadcde077f0845e6bb20c074 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 69 5.8E-22 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 THSYN_RS09740 d89777aceadcde077f0845e6bb20c074 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 73 141 1.6E-22 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 THSYN_RS09740 d89777aceadcde077f0845e6bb20c074 142 SUPERFAMILY SSF50331 1 69 1.7E-20 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal THSYN_RS09740 d89777aceadcde077f0845e6bb20c074 142 Gene3D G3DSA:2.40.50.100 1 64 4.4E-20 T 29-03-2018 THSYN_RS09740 d89777aceadcde077f0845e6bb20c074 142 SUPERFAMILY SSF50331 73 141 4.86E-20 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal THSYN_RS09740 d89777aceadcde077f0845e6bb20c074 142 Pfam PF03459 TOBE domain 4 65 2.6E-15 T 29-03-2018 IPR005116 Transport-associated OB, type 1 THSYN_RS09740 d89777aceadcde077f0845e6bb20c074 142 Pfam PF03459 TOBE domain 76 138 1.7E-13 T 29-03-2018 IPR005116 Transport-associated OB, type 1 THSYN_RS20220 83916d1dd025d360ed6857bd7dc5c1d3 194 Pfam PF01797 Transposase IS200 like 13 86 7.4E-7 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS20220 83916d1dd025d360ed6857bd7dc5c1d3 194 SUPERFAMILY SSF143422 1 87 5.76E-14 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS20220 83916d1dd025d360ed6857bd7dc5c1d3 194 SMART SM01321 9 110 3.0E-13 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS20220 83916d1dd025d360ed6857bd7dc5c1d3 194 Gene3D G3DSA:3.30.70.1290 7 111 3.9E-14 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS15535 5693a6369c682b0b0c28222c8ec3636b 413 Pfam PF13699 Domain of unknown function (DUF4157) 150 226 5.5E-27 T 29-03-2018 IPR025295 Domain of unknown function DUF4157 THSYN_RS05535 6648012719b95e9234b2c5fdc3ed65a7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 8.8E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS05535 6648012719b95e9234b2c5fdc3ed65a7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 8.8E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS05535 6648012719b95e9234b2c5fdc3ed65a7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 8.8E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS05535 6648012719b95e9234b2c5fdc3ed65a7 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 214 3.3E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS05535 6648012719b95e9234b2c5fdc3ed65a7 222 Gene3D G3DSA:1.10.10.10 129 222 2.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS05535 6648012719b95e9234b2c5fdc3ed65a7 222 Gene3D G3DSA:3.40.50.2300 8 128 2.2E-21 T 29-03-2018 THSYN_RS05535 6648012719b95e9234b2c5fdc3ed65a7 222 SUPERFAMILY SSF52172 12 143 4.7E-23 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS05535 6648012719b95e9234b2c5fdc3ed65a7 222 SMART SM00448 11 126 3.7E-12 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS05535 6648012719b95e9234b2c5fdc3ed65a7 222 SMART SM00421 159 216 3.0E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS05535 6648012719b95e9234b2c5fdc3ed65a7 222 SUPERFAMILY SSF46894 155 222 1.46E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS05535 6648012719b95e9234b2c5fdc3ed65a7 222 Pfam PF00072 Response regulator receiver domain 13 116 5.0E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS23070 93357e2d56f581528fdc728dba2a83b1 126 Gene3D G3DSA:1.10.260.40 8 93 9.0E-13 T 29-03-2018 THSYN_RS23070 93357e2d56f581528fdc728dba2a83b1 126 SUPERFAMILY SSF47413 31 93 1.69E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS23070 93357e2d56f581528fdc728dba2a83b1 126 Pfam PF13744 Helix-turn-helix domain 11 88 7.7E-11 T 29-03-2018 THSYN_RS23070 93357e2d56f581528fdc728dba2a83b1 126 SMART SM00530 32 86 5.5E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS29155 178d9393d3447b75db43bbc0fde6e703 460 Gene3D G3DSA:2.40.10.170 1 73 8.0E-28 T 29-03-2018 THSYN_RS29155 178d9393d3447b75db43bbc0fde6e703 460 Gene3D G3DSA:3.40.50.300 74 345 3.0E-97 T 29-03-2018 THSYN_RS29155 178d9393d3447b75db43bbc0fde6e703 460 SUPERFAMILY SSF52540 75 345 3.78E-94 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29155 178d9393d3447b75db43bbc0fde6e703 460 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 331 340 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS29155 178d9393d3447b75db43bbc0fde6e703 460 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 458 1.3E-248 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 THSYN_RS29155 178d9393d3447b75db43bbc0fde6e703 460 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 128 340 3.6E-67 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS29155 178d9393d3447b75db43bbc0fde6e703 460 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 71 1.3E-20 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS29155 178d9393d3447b75db43bbc0fde6e703 460 SMART SM00382 140 403 9.3E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS29155 178d9393d3447b75db43bbc0fde6e703 460 SUPERFAMILY SSF50615 2 73 2.62E-24 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS29155 178d9393d3447b75db43bbc0fde6e703 460 SUPERFAMILY SSF47917 343 458 2.04E-52 T 29-03-2018 THSYN_RS29155 178d9393d3447b75db43bbc0fde6e703 460 Gene3D G3DSA:1.10.1140.10 346 456 9.6E-43 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS29155 178d9393d3447b75db43bbc0fde6e703 460 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 458 56.766 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 THSYN_RS15355 b99170bfa555044eca115d6746f7c9fe 456 Gene3D G3DSA:3.90.350.10 60 342 5.3E-50 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS15355 b99170bfa555044eca115d6746f7c9fe 456 Gene3D G3DSA:1.10.246.40 4 59 1.1E-18 T 29-03-2018 THSYN_RS15355 b99170bfa555044eca115d6746f7c9fe 456 Pfam PF02281 Transposase Tn5 dimerisation domain 356 443 2.0E-19 T 29-03-2018 IPR003201 Transposase Tn5, dimerisation THSYN_RS15355 b99170bfa555044eca115d6746f7c9fe 456 Gene3D G3DSA:1.10.740.10 344 448 6.0E-36 T 29-03-2018 IPR014737 Transposase, Tn5-like, C-terminal THSYN_RS15355 b99170bfa555044eca115d6746f7c9fe 456 SUPERFAMILY SSF53098 5 448 3.41E-120 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS15355 b99170bfa555044eca115d6746f7c9fe 456 Pfam PF14706 Transposase DNA-binding 5 59 5.5E-20 T 29-03-2018 IPR014735 Transposase, Tn5-like, N-terminal THSYN_RS15355 b99170bfa555044eca115d6746f7c9fe 456 Pfam PF01609 Transposase DDE domain 263 349 1.6E-5 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS05900 4c0305c2180a9ece33917c6382357406 368 Gene3D G3DSA:3.40.50.2000 187 346 9.6E-45 T 29-03-2018 THSYN_RS05900 4c0305c2180a9ece33917c6382357406 368 SUPERFAMILY SSF53756 19 367 1.26E-85 T 29-03-2018 THSYN_RS05900 4c0305c2180a9ece33917c6382357406 368 Gene3D G3DSA:3.40.50.2000 16 186 4.4E-24 T 29-03-2018 THSYN_RS05900 4c0305c2180a9ece33917c6382357406 368 Pfam PF00534 Glycosyl transferases group 1 184 344 2.6E-32 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS05900 4c0305c2180a9ece33917c6382357406 368 Pfam PF13439 Glycosyltransferase Family 4 30 170 7.0E-22 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS24900 ba6c0b89b9403d05773ac8a692b1af89 288 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 288 4.1E-93 T 29-03-2018 IPR005229 Conserved hypothetical protein CHP00255 THSYN_RS24900 ba6c0b89b9403d05773ac8a692b1af89 288 Pfam PF08340 Domain of unknown function (DUF1732) 204 288 1.5E-35 T 29-03-2018 IPR013551 Domain of unknown function DUF1732 THSYN_RS24900 ba6c0b89b9403d05773ac8a692b1af89 288 Pfam PF03755 YicC-like family, N-terminal region 2 153 8.5E-40 T 29-03-2018 IPR013527 YicC-like, N-terminal THSYN_RS05280 f79264c74c0be85bb1b923289be6d376 384 SUPERFAMILY SSF53271 46 200 1.34E-8 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like THSYN_RS05280 f79264c74c0be85bb1b923289be6d376 384 Pfam PF12500 TRSP domain C terminus to PRTase_2 275 351 1.7E-9 T 29-03-2018 IPR022537 TRSP domain THSYN_RS05280 f79264c74c0be85bb1b923289be6d376 384 PIRSF PIRSF020967 1 371 6.0E-78 T 29-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 THSYN_RS05280 f79264c74c0be85bb1b923289be6d376 384 Pfam PF15609 Phosphoribosyl transferase 26 219 2.2E-55 T 29-03-2018 THSYN_RS05280 f79264c74c0be85bb1b923289be6d376 384 Gene3D G3DSA:3.40.50.2020 13 212 2.7E-19 T 29-03-2018 THSYN_RS16295 f0ca40d0d514b6a8c66bfd6427f54871 120 Gene3D G3DSA:3.40.1620.10 1 107 1.6E-12 T 29-03-2018 THSYN_RS16295 f0ca40d0d514b6a8c66bfd6427f54871 120 SUPERFAMILY SSF143120 2 42 1.31E-7 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS16295 f0ca40d0d514b6a8c66bfd6427f54871 120 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 70 4.6E-10 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS16295 f0ca40d0d514b6a8c66bfd6427f54871 120 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 41 8.6E-8 T 29-03-2018 THSYN_RS00605 035920cd75aa345f64302ef52474a73e 1271 Gene3D G3DSA:1.10.510.10 1100 1267 1.5E-32 T 29-03-2018 THSYN_RS00605 035920cd75aa345f64302ef52474a73e 1271 Pfam PF08357 SEFIR domain 772 891 1.1E-6 T 29-03-2018 IPR013568 SEFIR domain THSYN_RS00605 035920cd75aa345f64302ef52474a73e 1271 Gene3D G3DSA:3.40.50.300 227 539 2.5E-4 T 29-03-2018 THSYN_RS00605 035920cd75aa345f64302ef52474a73e 1271 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 1024 1047 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 THSYN_RS00605 035920cd75aa345f64302ef52474a73e 1271 SMART SM00220 1018 1261 3.1E-34 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS00605 035920cd75aa345f64302ef52474a73e 1271 SUPERFAMILY SSF56112 1015 1260 1.75E-53 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS00605 035920cd75aa345f64302ef52474a73e 1271 Gene3D G3DSA:3.40.50.10140 766 926 4.5E-6 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS00605 035920cd75aa345f64302ef52474a73e 1271 Gene3D G3DSA:3.30.200.20 1011 1099 3.0E-18 T 29-03-2018 THSYN_RS00605 035920cd75aa345f64302ef52474a73e 1271 Pfam PF00069 Protein kinase domain 1018 1217 4.5E-35 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS00605 035920cd75aa345f64302ef52474a73e 1271 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 1137 1149 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 THSYN_RS26070 3d44f0ccc815b1d6379d9ebeb7334144 195 ProSitePatterns PS01071 grpE protein signature. 148 191 - T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THSYN_RS26070 3d44f0ccc815b1d6379d9ebeb7334144 195 SUPERFAMILY SSF51064 139 193 9.29E-17 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 THSYN_RS26070 3d44f0ccc815b1d6379d9ebeb7334144 195 Hamap MF_01151 Protein GrpE [grpE]. 18 193 18.399 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THSYN_RS26070 3d44f0ccc815b1d6379d9ebeb7334144 195 Gene3D G3DSA:3.90.20.20 31 136 1.9E-22 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 THSYN_RS26070 3d44f0ccc815b1d6379d9ebeb7334144 195 PRINTS PR00773 GrpE protein signature 145 160 9.1E-21 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THSYN_RS26070 3d44f0ccc815b1d6379d9ebeb7334144 195 PRINTS PR00773 GrpE protein signature 172 191 9.1E-21 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THSYN_RS26070 3d44f0ccc815b1d6379d9ebeb7334144 195 PRINTS PR00773 GrpE protein signature 90 105 9.1E-21 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THSYN_RS26070 3d44f0ccc815b1d6379d9ebeb7334144 195 PRINTS PR00773 GrpE protein signature 62 78 9.1E-21 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THSYN_RS26070 3d44f0ccc815b1d6379d9ebeb7334144 195 Pfam PF01025 GrpE 30 192 2.7E-45 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THSYN_RS26070 3d44f0ccc815b1d6379d9ebeb7334144 195 Gene3D G3DSA:2.30.22.10 137 193 2.8E-20 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 THSYN_RS26070 3d44f0ccc815b1d6379d9ebeb7334144 195 SUPERFAMILY SSF58014 40 137 1.24E-22 T 29-03-2018 THSYN_RS22975 694253b32f92ec26533c1cad68b6b4a9 802 Pfam PF04851 Type III restriction enzyme, res subunit 156 322 7.7E-34 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS22975 694253b32f92ec26533c1cad68b6b4a9 802 Pfam PF00271 Helicase conserved C-terminal domain 406 522 8.2E-6 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS22975 694253b32f92ec26533c1cad68b6b4a9 802 Pfam PF08463 EcoEI R protein C-terminal 640 796 4.1E-18 T 29-03-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 THSYN_RS22975 694253b32f92ec26533c1cad68b6b4a9 802 SMART SM00487 154 356 1.4E-11 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS22975 694253b32f92ec26533c1cad68b6b4a9 802 SUPERFAMILY SSF52540 386 531 3.22E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22975 694253b32f92ec26533c1cad68b6b4a9 802 SUPERFAMILY SSF52540 172 323 3.22E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22975 694253b32f92ec26533c1cad68b6b4a9 802 Gene3D G3DSA:3.40.50.300 392 543 2.0E-11 T 29-03-2018 THSYN_RS22975 694253b32f92ec26533c1cad68b6b4a9 802 Gene3D G3DSA:3.40.50.300 83 343 4.0E-26 T 29-03-2018 THSYN_RS17635 0e0205d746a693d4356eeb98d9916bb8 130 SUPERFAMILY SSF103247 5 123 4.58E-38 T 29-03-2018 IPR005180 Domain of unknown function DUF302 THSYN_RS17635 0e0205d746a693d4356eeb98d9916bb8 130 PIRSF PIRSF021774 1 128 6.8E-45 T 29-03-2018 IPR016796 Uncharacterised conserved protein UCP021774 THSYN_RS17635 0e0205d746a693d4356eeb98d9916bb8 130 Pfam PF03625 Domain of unknown function DUF302 34 97 7.6E-29 T 29-03-2018 IPR005180 Domain of unknown function DUF302 THSYN_RS17635 0e0205d746a693d4356eeb98d9916bb8 130 Gene3D G3DSA:3.30.310.70 1 127 1.6E-38 T 29-03-2018 IPR005180 Domain of unknown function DUF302 THSYN_RS22800 8127ae4e5a4a032cc4c2e52e176f4845 326 Pfam PF16363 GDP-mannose 4,6 dehydratase 11 314 1.4E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS22800 8127ae4e5a4a032cc4c2e52e176f4845 326 SUPERFAMILY SSF51735 5 320 1.63E-90 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS22800 8127ae4e5a4a032cc4c2e52e176f4845 326 Gene3D G3DSA:3.40.50.720 5 173 1.6E-31 T 29-03-2018 THSYN_RS22800 8127ae4e5a4a032cc4c2e52e176f4845 326 Gene3D G3DSA:3.90.25.10 174 321 2.5E-41 T 29-03-2018 THSYN_RS27810 965a65e857b55f2d7c2dd54d26919f4f 281 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 270 46.36 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 THSYN_RS27810 965a65e857b55f2d7c2dd54d26919f4f 281 Gene3D G3DSA:3.60.21.10 1 267 1.2E-43 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS27810 965a65e857b55f2d7c2dd54d26919f4f 281 Pfam PF00149 Calcineurin-like phosphoesterase 1 145 8.8E-10 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS27810 965a65e857b55f2d7c2dd54d26919f4f 281 PIRSF PIRSF000903 1 270 1.1E-109 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 THSYN_RS27810 965a65e857b55f2d7c2dd54d26919f4f 281 SUPERFAMILY SSF56300 1 264 5.45E-54 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS27810 965a65e857b55f2d7c2dd54d26919f4f 281 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 257 7.3E-91 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 THSYN_RS10325 ad4b04581d03eb812e0324737f6803fd 444 PIRSF PIRSF006444 11 444 1.9E-206 T 29-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 THSYN_RS10325 ad4b04581d03eb812e0324737f6803fd 444 Gene3D G3DSA:3.30.300.30 336 443 5.9E-10 T 29-03-2018 THSYN_RS10325 ad4b04581d03eb812e0324737f6803fd 444 Pfam PF14535 AMP-binding enzyme C-terminal domain 346 442 1.0E-31 T 29-03-2018 IPR028154 AMP-dependent ligase, C-terminal THSYN_RS10325 ad4b04581d03eb812e0324737f6803fd 444 Gene3D G3DSA:3.40.50.980 93 269 4.3E-23 T 29-03-2018 THSYN_RS10325 ad4b04581d03eb812e0324737f6803fd 444 SUPERFAMILY SSF56801 49 408 1.44E-60 T 29-03-2018 THSYN_RS10325 ad4b04581d03eb812e0324737f6803fd 444 Pfam PF00501 AMP-binding enzyme 95 296 1.1E-13 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THSYN_RS20700 950ce92389c7ed041139384f9cd44486 151 SUPERFAMILY SSF51283 5 150 2.88E-47 T 29-03-2018 IPR029054 dUTPase-like THSYN_RS20700 950ce92389c7ed041139384f9cd44486 151 Gene3D G3DSA:2.70.40.10 2 112 1.8E-33 T 29-03-2018 THSYN_RS20700 950ce92389c7ed041139384f9cd44486 151 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 150 31.054 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 THSYN_RS20700 950ce92389c7ed041139384f9cd44486 151 Pfam PF00692 dUTPase 16 149 2.1E-33 T 29-03-2018 IPR029054 dUTPase-like THSYN_RS20700 950ce92389c7ed041139384f9cd44486 151 Gene3D G3DSA:2.70.40.10 113 150 8.2E-12 T 29-03-2018 THSYN_RS20700 950ce92389c7ed041139384f9cd44486 151 TIGRFAM TIGR00576 dut: dUTP diphosphatase 11 149 2.0E-43 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 THSYN_RS08775 b579e216724e0dd84124d1a4a79d8c69 484 Gene3D G3DSA:3.30.420.10 108 383 4.8E-23 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS08775 b579e216724e0dd84124d1a4a79d8c69 484 Pfam PF00665 Integrase core domain 112 238 5.8E-15 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 THSYN_RS08775 b579e216724e0dd84124d1a4a79d8c69 484 Gene3D G3DSA:1.10.10.60 9 31 6.4E-5 T 29-03-2018 THSYN_RS08775 b579e216724e0dd84124d1a4a79d8c69 484 Gene3D G3DSA:1.10.10.10 32 80 2.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS08775 b579e216724e0dd84124d1a4a79d8c69 484 SUPERFAMILY SSF53098 111 277 5.88E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS06740 b579e216724e0dd84124d1a4a79d8c69 484 Gene3D G3DSA:3.30.420.10 108 383 4.8E-23 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS06740 b579e216724e0dd84124d1a4a79d8c69 484 Pfam PF00665 Integrase core domain 112 238 5.8E-15 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 THSYN_RS06740 b579e216724e0dd84124d1a4a79d8c69 484 Gene3D G3DSA:1.10.10.60 9 31 6.4E-5 T 29-03-2018 THSYN_RS06740 b579e216724e0dd84124d1a4a79d8c69 484 Gene3D G3DSA:1.10.10.10 32 80 2.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS06740 b579e216724e0dd84124d1a4a79d8c69 484 SUPERFAMILY SSF53098 111 277 5.88E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS27580 b579e216724e0dd84124d1a4a79d8c69 484 Gene3D G3DSA:3.30.420.10 108 383 4.8E-23 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS27580 b579e216724e0dd84124d1a4a79d8c69 484 Pfam PF00665 Integrase core domain 112 238 5.8E-15 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 THSYN_RS27580 b579e216724e0dd84124d1a4a79d8c69 484 Gene3D G3DSA:1.10.10.60 9 31 6.4E-5 T 29-03-2018 THSYN_RS27580 b579e216724e0dd84124d1a4a79d8c69 484 Gene3D G3DSA:1.10.10.10 32 80 2.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS27580 b579e216724e0dd84124d1a4a79d8c69 484 SUPERFAMILY SSF53098 111 277 5.88E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS20105 c278e1bb9d27bdbed72d5b8b4c713539 213 SUPERFAMILY SSF69593 11 201 9.81E-28 T 29-03-2018 THSYN_RS20105 c278e1bb9d27bdbed72d5b8b4c713539 213 Gene3D G3DSA:3.40.1130.10 4 199 3.5E-29 T 29-03-2018 THSYN_RS20105 c278e1bb9d27bdbed72d5b8b4c713539 213 Pfam PF01553 Acyltransferase 33 152 5.3E-12 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THSYN_RS20105 c278e1bb9d27bdbed72d5b8b4c713539 213 SMART SM00563 35 156 2.3E-12 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THSYN_RS22550 17686d8375d724aced35a3707368347e 253 Pfam PF01578 Cytochrome C assembly protein 27 182 6.6E-23 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 THSYN_RS22550 17686d8375d724aced35a3707368347e 253 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 160 186 2.4E-28 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22550 17686d8375d724aced35a3707368347e 253 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 208 232 2.4E-28 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22550 17686d8375d724aced35a3707368347e 253 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 104 124 2.4E-28 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22550 17686d8375d724aced35a3707368347e 253 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 125 145 2.4E-28 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22550 17686d8375d724aced35a3707368347e 253 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 66 86 2.4E-28 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22550 17686d8375d724aced35a3707368347e 253 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 49 66 2.4E-28 T 29-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS08595 0a59f5814038680d6522b75e16954ce5 130 Pfam PF01850 PIN domain 2 119 4.5E-15 T 29-03-2018 IPR002716 PIN domain THSYN_RS08595 0a59f5814038680d6522b75e16954ce5 130 SUPERFAMILY SSF88723 1 121 7.57E-23 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS08595 0a59f5814038680d6522b75e16954ce5 130 Gene3D G3DSA:3.40.50.1010 1 129 5.2E-22 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS08645 0f431a586f66abc10fcbc4d57a2224ab 304 Pfam PF12483 E3 Ubiquitin ligase 93 182 2.2E-5 T 29-03-2018 IPR022170 E3 Ubiquitin ligase, GIDE-type GO:0004842|GO:0006996|GO:0016567 Reactome: R-HSA-5689880 THSYN_RS08645 0f431a586f66abc10fcbc4d57a2224ab 304 ProSitePatterns PS00018 EF-hand calcium-binding domain. 213 225 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS13885 0ebb8215a217a28b672a42148f23d5d6 271 Gene3D G3DSA:1.10.3540.10 27 204 1.3E-17 T 29-03-2018 THSYN_RS02465 66cb7ab3f697030f57572a83a774081a 386 Gene3D G3DSA:3.40.50.2000 8 165 4.8E-4 T 29-03-2018 THSYN_RS02465 66cb7ab3f697030f57572a83a774081a 386 Gene3D G3DSA:3.40.50.2000 166 342 2.7E-43 T 29-03-2018 THSYN_RS02465 66cb7ab3f697030f57572a83a774081a 386 Pfam PF00534 Glycosyl transferases group 1 175 337 4.8E-34 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS02465 66cb7ab3f697030f57572a83a774081a 386 SUPERFAMILY SSF53756 9 352 4.4E-56 T 29-03-2018 THSYN_RS19540 08736faf8ff944b7d2e45ddcc9bb6942 767 Gene3D G3DSA:3.40.718.10 454 730 2.2E-47 T 29-03-2018 THSYN_RS19540 08736faf8ff944b7d2e45ddcc9bb6942 767 SMART SM00919 170 407 6.7E-133 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 THSYN_RS19540 08736faf8ff944b7d2e45ddcc9bb6942 767 PIRSF PIRSF036684 5 767 0.0 T 29-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 THSYN_RS19540 08736faf8ff944b7d2e45ddcc9bb6942 767 Pfam PF01515 Phosphate acetyl/butaryl transferase 437 759 6.5E-83 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS19540 08736faf8ff944b7d2e45ddcc9bb6942 767 Pfam PF03949 Malic enzyme, NAD binding domain 172 366 1.3E-19 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 THSYN_RS19540 08736faf8ff944b7d2e45ddcc9bb6942 767 SUPERFAMILY SSF53659 436 763 4.93E-80 T 29-03-2018 THSYN_RS19540 08736faf8ff944b7d2e45ddcc9bb6942 767 SUPERFAMILY SSF53223 17 168 7.19E-51 T 29-03-2018 THSYN_RS19540 08736faf8ff944b7d2e45ddcc9bb6942 767 SMART SM01274 25 158 1.6E-76 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 THSYN_RS19540 08736faf8ff944b7d2e45ddcc9bb6942 767 SUPERFAMILY SSF51735 170 446 5.85E-82 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS19540 08736faf8ff944b7d2e45ddcc9bb6942 767 Pfam PF00390 Malic enzyme, N-terminal domain 26 157 5.7E-25 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 THSYN_RS19540 08736faf8ff944b7d2e45ddcc9bb6942 767 Gene3D G3DSA:3.40.50.720 168 450 7.1E-80 T 29-03-2018 THSYN_RS19540 08736faf8ff944b7d2e45ddcc9bb6942 767 Gene3D G3DSA:3.40.50.10380 12 167 4.7E-34 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 THSYN_RS18995 8df12d4e05093c2cda4bdc7ab7182a5f 327 TIGRFAM TIGR01905 paired_CXXCH_1: doubled CXXCH domain 154 191 2.4E-6 T 29-03-2018 IPR010177 Doubled CXXCH motif THSYN_RS18995 8df12d4e05093c2cda4bdc7ab7182a5f 327 SUPERFAMILY SSF48695 20 254 8.97E-28 T 29-03-2018 IPR011031 Multihaem cytochrome THSYN_RS18995 8df12d4e05093c2cda4bdc7ab7182a5f 327 Gene3D G3DSA:1.10.3820.10 7 184 1.4E-18 T 29-03-2018 THSYN_RS18995 8df12d4e05093c2cda4bdc7ab7182a5f 327 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 150 191 1.2E-5 T 29-03-2018 IPR010177 Doubled CXXCH motif THSYN_RS18995 8df12d4e05093c2cda4bdc7ab7182a5f 327 Gene3D G3DSA:1.10.1130.10 185 267 4.7E-8 T 29-03-2018 THSYN_RS09915 6e8cfd378673be242261facd9e54ccd4 598 Pfam PF06472 ABC transporter transmembrane region 2 15 284 1.6E-48 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS09915 6e8cfd378673be242261facd9e54ccd4 598 SUPERFAMILY SSF52540 353 576 1.57E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09915 6e8cfd378673be242261facd9e54ccd4 598 Gene3D G3DSA:1.20.1560.10 10 341 1.1E-39 T 29-03-2018 THSYN_RS09915 6e8cfd378673be242261facd9e54ccd4 598 Gene3D G3DSA:3.40.50.300 353 580 7.8E-18 T 29-03-2018 THSYN_RS09915 6e8cfd378673be242261facd9e54ccd4 598 ProSitePatterns PS00211 ABC transporters family signature. 506 520 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS09915 6e8cfd378673be242261facd9e54ccd4 598 SUPERFAMILY SSF90123 32 318 1.7E-34 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS09915 6e8cfd378673be242261facd9e54ccd4 598 SUPERFAMILY SSF90123 510 519 1.7E-34 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 2 61 1.3E-11 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 Gene3D G3DSA:2.30.30.30 1 62 3.8E-11 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 Hamap MF_00646 Elongation factor P-like protein [yeiP]. 1 187 36.91 T 29-03-2018 IPR011897 Translation elongation factor P-like, YeiP THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 SUPERFAMILY SSF50104 2 63 1.2E-7 T 29-03-2018 IPR008991 Translation protein SH3-like domain THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 SMART SM01185 68 123 1.4E-13 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 PIRSF PIRSF005901 1 187 4.5E-61 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 SMART SM00841 131 186 5.2E-27 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 Pfam PF09285 Elongation factor P, C-terminal 131 186 3.7E-19 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 Gene3D G3DSA:2.40.50.140 66 129 2.3E-14 T 29-03-2018 THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 Gene3D G3DSA:2.40.50.140 131 186 2.9E-20 T 29-03-2018 THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 SUPERFAMILY SSF50249 130 187 3.6E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 121 1.6E-12 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 SUPERFAMILY SSF50249 67 128 1.84E-11 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS28235 11de6437e3dabb002088817d628e896a 187 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site THSYN_RS19305 af468f1dbcf946a0e5e3b8c26e8e1aa6 155 PIRSF PIRSF000027 9 154 6.9E-31 T 29-03-2018 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 THSYN_RS19305 af468f1dbcf946a0e5e3b8c26e8e1aa6 155 Gene3D G3DSA:1.20.120.10 27 153 4.1E-34 T 29-03-2018 THSYN_RS19305 af468f1dbcf946a0e5e3b8c26e8e1aa6 155 PRINTS PR00608 Class II cytochrome C signature 118 141 1.2E-9 T 29-03-2018 IPR015984 Cytochrome c prime, subgroup THSYN_RS19305 af468f1dbcf946a0e5e3b8c26e8e1aa6 155 PRINTS PR00608 Class II cytochrome C signature 141 152 1.2E-9 T 29-03-2018 IPR015984 Cytochrome c prime, subgroup THSYN_RS19305 af468f1dbcf946a0e5e3b8c26e8e1aa6 155 Pfam PF01322 Cytochrome C' 30 152 9.4E-34 T 29-03-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 THSYN_RS19305 af468f1dbcf946a0e5e3b8c26e8e1aa6 155 SUPERFAMILY SSF47175 27 154 7.51E-38 T 29-03-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 THSYN_RS17695 e8011b98b573fa720ba666b6530f649d 1083 Pfam PF04465 Protein of unknown function (DUF499) 173 366 5.3E-17 T 29-03-2018 IPR007555 Protein of unknown function DUF499 THSYN_RS11945 34047572fba80044a7c61b85383fe5aa 254 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 4 251 1.2E-38 T 29-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 THSYN_RS09255 bb91562202eda2cfd70df93b20c3af9a 223 Pfam PF04012 PspA/IM30 family 3 220 2.4E-52 T 29-03-2018 IPR007157 PspA/IM30 THSYN_RS09255 bb91562202eda2cfd70df93b20c3af9a 223 Gene3D G3DSA:1.20.1170.10 5 223 3.8E-5 T 29-03-2018 THSYN_RS27945 f5e06b33aed7babac95603806532582f 205 Pfam PF01947 Protein of unknown function (DUF98) 49 201 1.4E-11 T 29-03-2018 IPR002800 Chorismate pyruvate-lyase Rv2949c-like THSYN_RS27945 f5e06b33aed7babac95603806532582f 205 Gene3D G3DSA:3.40.1410.10 39 204 5.0E-31 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain THSYN_RS27945 f5e06b33aed7babac95603806532582f 205 SUPERFAMILY SSF64288 41 202 3.4E-36 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain THSYN_RS29630 d055098aace60c523c33e187c882685d 417 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 77 394 1.7E-62 T 29-03-2018 IPR003776 YcaO-like domain THSYN_RS29630 d055098aace60c523c33e187c882685d 417 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 29 394 4.1E-57 T 29-03-2018 IPR003776 YcaO-like domain THSYN_RS24820 43421d25648f973ebf8f48999376ee8c 455 SUPERFAMILY SSF53335 12 203 1.23E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS24820 43421d25648f973ebf8f48999376ee8c 455 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 95 107 4.3E-9 T 29-03-2018 THSYN_RS24820 43421d25648f973ebf8f48999376ee8c 455 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 126 150 4.3E-9 T 29-03-2018 THSYN_RS24820 43421d25648f973ebf8f48999376ee8c 455 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 15 29 4.3E-9 T 29-03-2018 THSYN_RS24820 43421d25648f973ebf8f48999376ee8c 455 Gene3D G3DSA:3.40.50.150 7 224 3.0E-18 T 29-03-2018 THSYN_RS24820 43421d25648f973ebf8f48999376ee8c 455 Pfam PF07669 Eco57I restriction-modification methylase 99 198 6.2E-7 T 29-03-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 THSYN_RS00855 dad36ebfee95f0d4ba46494f4d3fd66b 446 Gene3D G3DSA:3.30.70.20 39 108 8.0E-4 T 29-03-2018 THSYN_RS00855 dad36ebfee95f0d4ba46494f4d3fd66b 446 Pfam PF02754 Cysteine-rich domain 209 294 1.8E-7 T 29-03-2018 IPR004017 Cysteine-rich domain THSYN_RS00855 dad36ebfee95f0d4ba46494f4d3fd66b 446 SUPERFAMILY SSF54862 36 99 6.28E-6 T 29-03-2018 THSYN_RS08235 8522ece0113ffc99c58eb07efd987635 286 Gene3D G3DSA:3.40.50.720 4 269 1.7E-37 T 29-03-2018 THSYN_RS08235 8522ece0113ffc99c58eb07efd987635 286 Pfam PF00899 ThiF family 13 259 5.3E-36 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THSYN_RS08235 8522ece0113ffc99c58eb07efd987635 286 SUPERFAMILY SSF69572 9 263 1.16E-45 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THSYN_RS23785 9d4bc1deeacb3dd4932ad9508ef181fe 130 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 117 6.2E-46 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23785 9d4bc1deeacb3dd4932ad9508ef181fe 130 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.279 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23785 9d4bc1deeacb3dd4932ad9508ef181fe 130 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23785 9d4bc1deeacb3dd4932ad9508ef181fe 130 Gene3D G3DSA:3.90.1030.10 1 117 1.4E-49 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23785 9d4bc1deeacb3dd4932ad9508ef181fe 130 Pfam PF01196 Ribosomal protein L17 20 116 2.6E-33 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23785 9d4bc1deeacb3dd4932ad9508ef181fe 130 SUPERFAMILY SSF64263 1 119 1.16E-50 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24540 1f3fad200429cdc4a6afd9275816f597 584 PRINTS PR00723 Subtilisin serine protease family (S8) signature 175 188 3.0E-18 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS24540 1f3fad200429cdc4a6afd9275816f597 584 PRINTS PR00723 Subtilisin serine protease family (S8) signature 328 344 3.0E-18 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS24540 1f3fad200429cdc4a6afd9275816f597 584 PRINTS PR00723 Subtilisin serine protease family (S8) signature 137 156 3.0E-18 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS24540 1f3fad200429cdc4a6afd9275816f597 584 Pfam PF00082 Subtilase family 137 379 1.2E-31 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS24540 1f3fad200429cdc4a6afd9275816f597 584 Gene3D G3DSA:2.60.40.10 388 489 9.0E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS24540 1f3fad200429cdc4a6afd9275816f597 584 Gene3D G3DSA:2.60.40.10 495 584 7.6E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS24540 1f3fad200429cdc4a6afd9275816f597 584 Gene3D G3DSA:3.40.50.200 82 387 7.1E-80 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS24540 1f3fad200429cdc4a6afd9275816f597 584 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 329 339 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site THSYN_RS24540 1f3fad200429cdc4a6afd9275816f597 584 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 142 153 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site THSYN_RS24540 1f3fad200429cdc4a6afd9275816f597 584 SUPERFAMILY SSF52743 101 393 1.83E-71 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS16850 1690f5fd764b410c1b580cd6c759547b 357 Gene3D G3DSA:3.40.50.2300 52 168 3.7E-23 T 29-03-2018 THSYN_RS16850 1690f5fd764b410c1b580cd6c759547b 357 Pfam PF13407 Periplasmic binding protein domain 54 314 1.6E-46 T 29-03-2018 IPR025997 Periplasmic binding protein THSYN_RS16850 1690f5fd764b410c1b580cd6c759547b 357 SUPERFAMILY SSF53822 52 333 8.34E-70 T 29-03-2018 IPR028082 Periplasmic binding protein-like I THSYN_RS16850 1690f5fd764b410c1b580cd6c759547b 357 Gene3D G3DSA:3.40.50.2300 169 337 3.0E-38 T 29-03-2018 THSYN_RS28465 f0ac794d218b05430d371d2bcb621935 60 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 5 46 4.3E-13 T 29-03-2018 IPR022453 Zinc finger, MqsA-type THSYN_RS03735 02910b6cdeeb812b11a2d101486675f6 392 SUPERFAMILY SSF55073 232 385 2.82E-48 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS03735 02910b6cdeeb812b11a2d101486675f6 392 SMART SM00267 216 387 2.0E-60 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS03735 02910b6cdeeb812b11a2d101486675f6 392 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 223 385 3.7E-49 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS03735 02910b6cdeeb812b11a2d101486675f6 392 Pfam PF00990 Diguanylate cyclase, GGDEF domain 227 383 1.0E-43 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS03735 02910b6cdeeb812b11a2d101486675f6 392 Gene3D G3DSA:3.30.70.270 210 387 3.5E-58 T 29-03-2018 THSYN_RS31665 94a91e9aebe7d895cf7ae5bfef3babdd 254 TIGRFAM TIGR01150 puhA: photosynthetic reaction center H subunit 7 249 1.1E-79 T 29-03-2018 IPR005652 Photosynthetic reaction centre, H subunit GO:0019684|GO:0030077|GO:0045156 THSYN_RS31665 94a91e9aebe7d895cf7ae5bfef3babdd 254 SUPERFAMILY SSF50346 35 250 1.06E-69 T 29-03-2018 IPR011033 PRC-barrel-like THSYN_RS31665 94a91e9aebe7d895cf7ae5bfef3babdd 254 Pfam PF05239 PRC-barrel domain 144 205 4.2E-12 T 29-03-2018 IPR027275 PRC-barrel domain THSYN_RS31665 94a91e9aebe7d895cf7ae5bfef3babdd 254 SUPERFAMILY SSF81490 7 42 3.34E-14 T 29-03-2018 THSYN_RS31665 94a91e9aebe7d895cf7ae5bfef3babdd 254 Gene3D G3DSA:3.90.50.10 115 253 2.2E-21 T 29-03-2018 THSYN_RS31665 94a91e9aebe7d895cf7ae5bfef3babdd 254 Gene3D G3DSA:4.10.540.10 4 112 1.2E-41 T 29-03-2018 IPR015810 Photosynthetic reaction centre, H subunit, N-terminal GO:0019684|GO:0030077|GO:0045156 THSYN_RS31665 94a91e9aebe7d895cf7ae5bfef3babdd 254 Pfam PF03967 Photosynthetic reaction centre, H-chain N-terminal region 7 134 7.2E-48 T 29-03-2018 IPR015810 Photosynthetic reaction centre, H subunit, N-terminal GO:0019684|GO:0030077|GO:0045156 THSYN_RS02070 ad93d6258f2187814b51d234e954e9ea 204 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 11 169 21.443 T 29-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 THSYN_RS02070 ad93d6258f2187814b51d234e954e9ea 204 Pfam PF03968 OstA-like protein 42 150 2.8E-25 T 29-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal THSYN_RS02070 ad93d6258f2187814b51d234e954e9ea 204 Gene3D G3DSA:2.60.450.10 31 167 2.0E-24 T 29-03-2018 THSYN_RS02070 ad93d6258f2187814b51d234e954e9ea 204 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 31 168 1.2E-36 T 29-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 THSYN_RS09560 8efd550f4ccc9fa28eaa88e0747bae98 89 Pfam PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain 36 85 1.9E-11 T 29-03-2018 IPR002223 Pancreatic trypsin inhibitor Kunitz domain GO:0004867 THSYN_RS09560 8efd550f4ccc9fa28eaa88e0747bae98 89 SUPERFAMILY SSF57362 33 86 3.26E-13 T 29-03-2018 IPR002223 Pancreatic trypsin inhibitor Kunitz domain GO:0004867 THSYN_RS09560 8efd550f4ccc9fa28eaa88e0747bae98 89 Gene3D G3DSA:4.10.410.10 30 87 5.0E-15 T 29-03-2018 IPR002223 Pancreatic trypsin inhibitor Kunitz domain GO:0004867 THSYN_RS09560 8efd550f4ccc9fa28eaa88e0747bae98 89 SMART SM00131 34 86 1.3E-6 T 29-03-2018 IPR002223 Pancreatic trypsin inhibitor Kunitz domain GO:0004867 THSYN_RS05085 453211fc4483f11fefdbab139744862a 305 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 32 291 9.7E-123 T 29-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 THSYN_RS05085 453211fc4483f11fefdbab139744862a 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 289 5.2E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS05085 453211fc4483f11fefdbab139744862a 305 Gene3D G3DSA:1.10.3720.10 34 293 8.9E-42 T 29-03-2018 THSYN_RS05085 453211fc4483f11fefdbab139744862a 305 SUPERFAMILY SSF161098 30 285 3.27E-56 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS05085 453211fc4483f11fefdbab139744862a 305 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 32 288 7.9E-99 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 THSYN_RS02835 1f177969870143c6cadd3afbc0e0b5f1 480 Gene3D G3DSA:3.30.470.20 340 472 0.0015 T 29-03-2018 THSYN_RS02835 1f177969870143c6cadd3afbc0e0b5f1 480 SUPERFAMILY SSF56059 326 471 1.07E-59 T 29-03-2018 THSYN_RS02835 1f177969870143c6cadd3afbc0e0b5f1 480 SUPERFAMILY SSF56059 34 218 1.07E-59 T 29-03-2018 THSYN_RS02835 1f177969870143c6cadd3afbc0e0b5f1 480 Pfam PF14403 Circularly permuted ATP-grasp type 2 80 456 9.6E-160 T 29-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 THSYN_RS02835 1f177969870143c6cadd3afbc0e0b5f1 480 PIRSF PIRSF005522 2 480 1.8E-215 T 29-03-2018 IPR016450 Uncharacterised conserved protein UCP005522 THSYN_RS21230 00c84f7c5d9446ae8729bba87311ce94 639 Gene3D G3DSA:3.40.50.300 23 207 4.4E-14 T 29-03-2018 THSYN_RS21230 00c84f7c5d9446ae8729bba87311ce94 639 SUPERFAMILY SSF52540 6 265 1.19E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21230 00c84f7c5d9446ae8729bba87311ce94 639 Pfam PF01471 Putative peptidoglycan binding domain 537 591 2.5E-8 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS21230 00c84f7c5d9446ae8729bba87311ce94 639 SMART SM00382 42 185 2.8E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS21230 00c84f7c5d9446ae8729bba87311ce94 639 Gene3D G3DSA:3.90.70.10 414 527 1.0E-9 T 29-03-2018 THSYN_RS21230 00c84f7c5d9446ae8729bba87311ce94 639 SMART SM00487 20 183 0.0096 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS21230 00c84f7c5d9446ae8729bba87311ce94 639 Pfam PF13401 AAA domain 42 172 5.8E-24 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS21230 00c84f7c5d9446ae8729bba87311ce94 639 Gene3D G3DSA:1.10.101.10 528 596 3.1E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS21230 00c84f7c5d9446ae8729bba87311ce94 639 SUPERFAMILY SSF47090 520 592 7.06E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS16475 94be62358c9ed75e089a0d98cf055ab7 300 Pfam PF00535 Glycosyl transferase family 2 32 137 5.2E-26 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS16475 94be62358c9ed75e089a0d98cf055ab7 300 Gene3D G3DSA:3.90.550.10 8 264 5.6E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS16475 94be62358c9ed75e089a0d98cf055ab7 300 SUPERFAMILY SSF53448 29 257 3.66E-51 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS05735 169e419e15fe52283bc390bdb5307df3 77 Pfam PF04255 Protein of unknown function (DUF433) 5 60 1.9E-23 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS05735 169e419e15fe52283bc390bdb5307df3 77 Gene3D G3DSA:1.10.10.10 5 68 1.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS05735 169e419e15fe52283bc390bdb5307df3 77 SUPERFAMILY SSF46689 4 68 1.59E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS10210 f89433e5fd14e76615bfec400de1f882 196 SMART SM00260 42 188 5.8E-7 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS10210 f89433e5fd14e76615bfec400de1f882 196 Gene3D G3DSA:2.40.50.180 71 135 1.8E-14 T 29-03-2018 THSYN_RS10210 f89433e5fd14e76615bfec400de1f882 196 Gene3D G3DSA:2.30.30.40 136 182 0.024 T 29-03-2018 THSYN_RS10210 f89433e5fd14e76615bfec400de1f882 196 Pfam PF01584 CheW-like domain 55 187 2.1E-21 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS10210 f89433e5fd14e76615bfec400de1f882 196 SUPERFAMILY SSF50341 48 188 8.5E-25 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS19790 8aac99e1dae30c964b7f0d8c7edee862 440 SUPERFAMILY SSF53335 70 439 1.34E-83 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS19790 8aac99e1dae30c964b7f0d8c7edee862 440 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 370 400 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site THSYN_RS19790 8aac99e1dae30c964b7f0d8c7edee862 440 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 422 432 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site THSYN_RS19790 8aac99e1dae30c964b7f0d8c7edee862 440 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 268 439 1.2E-21 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 THSYN_RS19790 8aac99e1dae30c964b7f0d8c7edee862 440 Gene3D G3DSA:2.40.50.140 2 77 6.6E-26 T 29-03-2018 THSYN_RS19790 8aac99e1dae30c964b7f0d8c7edee862 440 Gene3D G3DSA:3.40.50.150 78 438 3.9E-56 T 29-03-2018 THSYN_RS19790 8aac99e1dae30c964b7f0d8c7edee862 440 SUPERFAMILY SSF50249 11 69 9.14E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS19790 8aac99e1dae30c964b7f0d8c7edee862 440 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 19 432 4.2E-94 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 THSYN_RS19790 8aac99e1dae30c964b7f0d8c7edee862 440 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 13 440 65.465 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 THSYN_RS17215 10fd02b33e419cc28dfb6e41fbe4e270 276 SUPERFAMILY SSF56219 3 243 1.7E-34 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase THSYN_RS17215 10fd02b33e419cc28dfb6e41fbe4e270 276 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 235 5.7E-18 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase THSYN_RS17215 10fd02b33e419cc28dfb6e41fbe4e270 276 Gene3D G3DSA:3.60.10.10 1 243 3.9E-28 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase THSYN_RS05250 c9192502322047e0642f3567f75b1a52 191 Pfam PF02342 TerD domain 2 175 2.7E-44 T 29-03-2018 IPR003325 TerD domain GO:0006950 THSYN_RS05250 c9192502322047e0642f3567f75b1a52 191 Gene3D G3DSA:2.60.60.30 20 184 2.2E-42 T 29-03-2018 THSYN_RS12505 9ce69551fa455fecd93b583d1b2402a6 777 Gene3D G3DSA:1.10.510.10 100 328 1.3E-44 T 29-03-2018 THSYN_RS12505 9ce69551fa455fecd93b583d1b2402a6 777 SUPERFAMILY SSF56112 12 274 1.12E-66 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS12505 9ce69551fa455fecd93b583d1b2402a6 777 SMART SM00382 547 682 1.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS12505 9ce69551fa455fecd93b583d1b2402a6 777 SUPERFAMILY SSF52540 516 749 3.66E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12505 9ce69551fa455fecd93b583d1b2402a6 777 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 551 679 9.3E-26 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS12505 9ce69551fa455fecd93b583d1b2402a6 777 Gene3D G3DSA:1.10.8.60 689 763 2.2E-7 T 29-03-2018 THSYN_RS12505 9ce69551fa455fecd93b583d1b2402a6 777 Pfam PF00069 Protein kinase domain 19 268 1.8E-43 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS12505 9ce69551fa455fecd93b583d1b2402a6 777 SMART SM00220 16 281 1.7E-47 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS12505 9ce69551fa455fecd93b583d1b2402a6 777 Gene3D G3DSA:3.30.200.20 6 99 3.2E-17 T 29-03-2018 THSYN_RS12505 9ce69551fa455fecd93b583d1b2402a6 777 Gene3D G3DSA:3.40.50.300 387 688 2.4E-31 T 29-03-2018 THSYN_RS33160 0dd3f30a142f8fc4dc91a415dac593ba 103 SUPERFAMILY SSF46626 15 102 1.43E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS33160 0dd3f30a142f8fc4dc91a415dac593ba 103 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 21 99 2.9E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS33160 0dd3f30a142f8fc4dc91a415dac593ba 103 Gene3D G3DSA:1.10.760.10 3 102 7.0E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS31465 ee3880592e2fa70047f7ec885a61237c 361 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 37 317 9.2E-60 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 THSYN_RS31465 ee3880592e2fa70047f7ec885a61237c 361 Gene3D G3DSA:3.40.190.10 159 292 0.0021 T 29-03-2018 THSYN_RS31465 ee3880592e2fa70047f7ec885a61237c 361 SUPERFAMILY SSF53850 132 274 2.71E-5 T 29-03-2018 THSYN_RS31465 ee3880592e2fa70047f7ec885a61237c 361 PIRSF PIRSF039026 1 354 9.7E-124 T 29-03-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like THSYN_RS21420 544e8b300d12f7bc146f1bc30ad843bd 699 Pfam PF02384 N-6 DNA Methylase 170 467 3.1E-56 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS21420 544e8b300d12f7bc146f1bc30ad843bd 699 Pfam PF12161 HsdM N-terminal domain 9 134 5.8E-18 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS21420 544e8b300d12f7bc146f1bc30ad843bd 699 Gene3D G3DSA:3.40.50.150 191 605 5.8E-47 T 29-03-2018 THSYN_RS21420 544e8b300d12f7bc146f1bc30ad843bd 699 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 226 240 2.5E-11 T 29-03-2018 THSYN_RS21420 544e8b300d12f7bc146f1bc30ad843bd 699 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 298 310 2.5E-11 T 29-03-2018 THSYN_RS21420 544e8b300d12f7bc146f1bc30ad843bd 699 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 193 209 2.5E-11 T 29-03-2018 THSYN_RS21420 544e8b300d12f7bc146f1bc30ad843bd 699 SUPERFAMILY SSF53335 6 44 1.44E-115 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS21420 544e8b300d12f7bc146f1bc30ad843bd 699 SUPERFAMILY SSF53335 75 541 1.44E-115 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS21420 544e8b300d12f7bc146f1bc30ad843bd 699 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 301 307 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS29075 33d0fef5e20883ad66e46953d7914e94 335 Pfam PF13616 PPIC-type PPIASE domain 162 260 1.3E-24 T 29-03-2018 THSYN_RS29075 33d0fef5e20883ad66e46953d7914e94 335 SUPERFAMILY SSF54534 157 263 1.24E-27 T 29-03-2018 THSYN_RS29075 33d0fef5e20883ad66e46953d7914e94 335 Gene3D G3DSA:3.10.50.40 152 284 5.8E-37 T 29-03-2018 THSYN_RS23175 3195b4655412007ce27dec38737ecee2 470 Gene3D G3DSA:3.60.120.10 48 470 1.0E-84 T 29-03-2018 IPR005801 ADC synthase GO:0009058 THSYN_RS23175 3195b4655412007ce27dec38737ecee2 470 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 131 466 2.3E-76 T 29-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 THSYN_RS23175 3195b4655412007ce27dec38737ecee2 470 SUPERFAMILY SSF56322 41 468 1.44E-88 T 29-03-2018 IPR005801 ADC synthase GO:0009058 THSYN_RS23175 3195b4655412007ce27dec38737ecee2 470 Pfam PF00425 chorismate binding enzyme 203 459 7.7E-68 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal THSYN_RS15875 fc907f24907169ac1147ffc293bc5608 115 SUPERFAMILY SSF46785 42 94 1.12E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS15875 fc907f24907169ac1147ffc293bc5608 115 Gene3D G3DSA:1.10.10.10 8 114 1.2E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS24800 59074df671aaee60c60847c23ec83d39 343 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 21 306 6.2E-71 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 THSYN_RS24800 59074df671aaee60c60847c23ec83d39 343 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 2 321 38.165 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 THSYN_RS24800 59074df671aaee60c60847c23ec83d39 343 Gene3D G3DSA:3.40.50.300 44 314 1.3E-4 T 29-03-2018 THSYN_RS24800 59074df671aaee60c60847c23ec83d39 343 SUPERFAMILY SSF52540 48 182 3.79E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24800 59074df671aaee60c60847c23ec83d39 343 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 15 319 1.4E-99 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 THSYN_RS01965 ac519af86c68c0d703ae4a6e2fd08670 428 Gene3D G3DSA:3.40.50.720 228 426 3.1E-55 T 29-03-2018 THSYN_RS01965 ac519af86c68c0d703ae4a6e2fd08670 428 SUPERFAMILY SSF48179 204 296 1.02E-24 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THSYN_RS01965 ac519af86c68c0d703ae4a6e2fd08670 428 PIRSF PIRSF500136 1 428 1.4E-145 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 THSYN_RS01965 ac519af86c68c0d703ae4a6e2fd08670 428 SUPERFAMILY SSF52413 304 421 1.7E-26 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THSYN_RS01965 ac519af86c68c0d703ae4a6e2fd08670 428 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 321 419 6.7E-20 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THSYN_RS01965 ac519af86c68c0d703ae4a6e2fd08670 428 Gene3D G3DSA:1.20.5.170 205 227 2.0E-11 T 29-03-2018 THSYN_RS01965 ac519af86c68c0d703ae4a6e2fd08670 428 SMART SM00984 321 421 1.6E-32 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THSYN_RS01965 ac519af86c68c0d703ae4a6e2fd08670 428 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 11 184 1.2E-30 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THSYN_RS01965 ac519af86c68c0d703ae4a6e2fd08670 428 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 206 294 1.6E-23 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THSYN_RS01965 ac519af86c68c0d703ae4a6e2fd08670 428 SUPERFAMILY SSF51735 11 195 3.95E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS01965 ac519af86c68c0d703ae4a6e2fd08670 428 PIRSF PIRSF000124 10 425 2.8E-50 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THSYN_RS01965 ac519af86c68c0d703ae4a6e2fd08670 428 Gene3D G3DSA:3.40.50.720 4 203 7.8E-39 T 29-03-2018 THSYN_RS01965 ac519af86c68c0d703ae4a6e2fd08670 428 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 11 415 1.5E-115 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THSYN_RS26405 2ce282950be80d5671421c568014bcc2 129 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 129 30.234 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid THSYN_RS26405 2ce282950be80d5671421c568014bcc2 129 SUPERFAMILY SSF54211 5 129 2.43E-47 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS26405 2ce282950be80d5671421c568014bcc2 129 Gene3D G3DSA:3.30.230.10 2 129 5.2E-52 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS26405 2ce282950be80d5671421c568014bcc2 129 ProSitePatterns PS00360 Ribosomal protein S9 signature. 68 86 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 THSYN_RS26405 2ce282950be80d5671421c568014bcc2 129 Pfam PF00380 Ribosomal protein S9/S16 9 129 5.3E-45 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 THSYN_RS05175 c1e52096edf2ba7b5d891b68c0f2c633 218 SUPERFAMILY SSF52218 19 194 7.91E-45 T 29-03-2018 IPR029039 Flavoprotein-like domain THSYN_RS05175 c1e52096edf2ba7b5d891b68c0f2c633 218 Pfam PF02525 Flavodoxin-like fold 19 186 5.1E-39 T 29-03-2018 IPR003680 Flavodoxin-like fold THSYN_RS05175 c1e52096edf2ba7b5d891b68c0f2c633 218 Gene3D G3DSA:3.40.50.360 13 197 2.6E-30 T 29-03-2018 IPR029039 Flavoprotein-like domain THSYN_RS30790 61fc5498c9bb6d48e7bd49fa7864add8 436 Gene3D G3DSA:3.40.50.300 4 291 1.9E-4 T 29-03-2018 THSYN_RS30790 61fc5498c9bb6d48e7bd49fa7864add8 436 Pfam PF10923 P-loop Domain of unknown function (DUF2791) 2 411 6.8E-133 T 29-03-2018 IPR021228 Protein of unknown function DUF2791 THSYN_RS25495 bcc22fb16d3fb61373a35c4219cc005e 470 Gene3D G3DSA:3.40.50.150 129 407 1.7E-66 T 29-03-2018 THSYN_RS25495 bcc22fb16d3fb61373a35c4219cc005e 470 Pfam PF02353 Mycolic acid cyclopropane synthetase 137 402 4.1E-84 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS25495 bcc22fb16d3fb61373a35c4219cc005e 470 SUPERFAMILY SSF53335 142 406 6.08E-78 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02145 7c8844d2c414fbe41ec19f78a1f89acb 209 Gene3D G3DSA:1.20.950.20 20 209 9.9E-32 T 29-03-2018 THSYN_RS02145 7c8844d2c414fbe41ec19f78a1f89acb 209 Pfam PF01292 Prokaryotic cytochrome b561 27 202 1.2E-19 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THSYN_RS02145 7c8844d2c414fbe41ec19f78a1f89acb 209 SUPERFAMILY SSF81342 22 207 1.02E-33 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THSYN_RS12550 8f3155c0af1f9c4905c9f247458c605c 225 SUPERFAMILY SSF47819 130 202 5.45E-18 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 THSYN_RS12550 8f3155c0af1f9c4905c9f247458c605c 225 Gene3D G3DSA:1.10.150.80 133 202 2.5E-20 T 29-03-2018 THSYN_RS12550 8f3155c0af1f9c4905c9f247458c605c 225 SMART SM00341 130 211 3.9E-13 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 THSYN_RS12550 8f3155c0af1f9c4905c9f247458c605c 225 Pfam PF00570 HRDC domain 136 199 2.7E-19 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 THSYN_RS28805 2ca92b7aab45cdacd913614de0e0bb38 153 Pfam PF12161 HsdM N-terminal domain 8 36 3.2E-5 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS09265 8ce28c8d23710aed95802e303743506d 202 Gene3D G3DSA:3.90.1570.10 1 181 6.9E-28 T 29-03-2018 THSYN_RS09265 8ce28c8d23710aed95802e303743506d 202 Pfam PF05685 Putative restriction endonuclease 4 137 3.6E-22 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS09265 8ce28c8d23710aed95802e303743506d 202 SUPERFAMILY SSF52980 4 136 3.0E-15 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS23635 aa934d0f4b293199cb8fab8d767f8ed3 515 Gene3D G3DSA:3.90.350.10 176 442 1.8E-4 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS23635 aa934d0f4b293199cb8fab8d767f8ed3 515 SUPERFAMILY SSF53098 142 482 9.86E-5 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS23635 aa934d0f4b293199cb8fab8d767f8ed3 515 Pfam PF13808 DDE_Tnp_1-associated 90 176 2.6E-15 T 29-03-2018 IPR032806 H repeat-associated protein, N-terminal THSYN_RS05530 aa934d0f4b293199cb8fab8d767f8ed3 515 Gene3D G3DSA:3.90.350.10 176 442 1.8E-4 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS05530 aa934d0f4b293199cb8fab8d767f8ed3 515 SUPERFAMILY SSF53098 142 482 9.86E-5 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS05530 aa934d0f4b293199cb8fab8d767f8ed3 515 Pfam PF13808 DDE_Tnp_1-associated 90 176 2.6E-15 T 29-03-2018 IPR032806 H repeat-associated protein, N-terminal THSYN_RS07775 aa934d0f4b293199cb8fab8d767f8ed3 515 Gene3D G3DSA:3.90.350.10 176 442 1.8E-4 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS07775 aa934d0f4b293199cb8fab8d767f8ed3 515 SUPERFAMILY SSF53098 142 482 9.86E-5 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS07775 aa934d0f4b293199cb8fab8d767f8ed3 515 Pfam PF13808 DDE_Tnp_1-associated 90 176 2.6E-15 T 29-03-2018 IPR032806 H repeat-associated protein, N-terminal THSYN_RS02095 aa934d0f4b293199cb8fab8d767f8ed3 515 Gene3D G3DSA:3.90.350.10 176 442 1.8E-4 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS02095 aa934d0f4b293199cb8fab8d767f8ed3 515 SUPERFAMILY SSF53098 142 482 9.86E-5 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS02095 aa934d0f4b293199cb8fab8d767f8ed3 515 Pfam PF13808 DDE_Tnp_1-associated 90 176 2.6E-15 T 29-03-2018 IPR032806 H repeat-associated protein, N-terminal THSYN_RS14555 aa934d0f4b293199cb8fab8d767f8ed3 515 Gene3D G3DSA:3.90.350.10 176 442 1.8E-4 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS14555 aa934d0f4b293199cb8fab8d767f8ed3 515 SUPERFAMILY SSF53098 142 482 9.86E-5 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS14555 aa934d0f4b293199cb8fab8d767f8ed3 515 Pfam PF13808 DDE_Tnp_1-associated 90 176 2.6E-15 T 29-03-2018 IPR032806 H repeat-associated protein, N-terminal THSYN_RS28770 cf9b048f2d1a68a41ca02cd2d8d0f8cd 412 Gene3D G3DSA:3.20.20.70 20 384 4.5E-5 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS28770 cf9b048f2d1a68a41ca02cd2d8d0f8cd 412 PIRSF PIRSF004640 7 412 1.4E-129 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 THSYN_RS28770 cf9b048f2d1a68a41ca02cd2d8d0f8cd 412 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 14 403 1.1E-117 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 THSYN_RS28770 cf9b048f2d1a68a41ca02cd2d8d0f8cd 412 Pfam PF04551 GcpE protein 19 404 1.0E-115 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 THSYN_RS28770 cf9b048f2d1a68a41ca02cd2d8d0f8cd 412 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 12 408 29.112 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 THSYN_RS24220 5839b55b9333d78f573624d56060148b 570 TIGRFAM TIGR04456 LruC_dom: LruC domain 315 559 7.5E-61 T 29-03-2018 IPR031025 LruC domain THSYN_RS24220 5839b55b9333d78f573624d56060148b 570 Pfam PF13448 Domain of unknown function (DUF4114) 179 262 1.8E-20 T 29-03-2018 IPR025193 Domain of unknown function DUF4114 THSYN_RS24220 5839b55b9333d78f573624d56060148b 570 Pfam PF16130 Domain of unknown function (DUF4842) 348 558 3.6E-39 T 29-03-2018 IPR032295 Domain of unknown function DUF4842 THSYN_RS01830 7a8d6134e3a35fafe634813d3663fa0e 163 Pfam PF11848 Domain of unknown function (DUF3368) 118 161 9.8E-11 T 29-03-2018 IPR021799 Protein of unknown function DUF3368 THSYN_RS22310 4ad91808563a17a270ac3b651ac78cbd 249 Gene3D G3DSA:1.10.10.200 1 78 2.5E-29 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like THSYN_RS22310 4ad91808563a17a270ac3b651ac78cbd 249 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 35.927 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THSYN_RS22310 4ad91808563a17a270ac3b651ac78cbd 249 Gene3D G3DSA:3.30.70.980 175 238 4.5E-6 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THSYN_RS22310 4ad91808563a17a270ac3b651ac78cbd 249 Gene3D G3DSA:3.30.70.980 83 174 9.3E-32 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THSYN_RS22310 4ad91808563a17a270ac3b651ac78cbd 249 Pfam PF01709 Transcriptional regulator 5 237 2.0E-91 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THSYN_RS22310 4ad91808563a17a270ac3b651ac78cbd 249 SUPERFAMILY SSF75625 3 245 2.22E-94 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THSYN_RS22310 4ad91808563a17a270ac3b651ac78cbd 249 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 2.3E-95 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THSYN_RS22570 95e2c565fa268bce2a088fd37007ef50 180 Pfam PF08534 Redoxin 38 161 3.4E-19 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 THSYN_RS22570 95e2c565fa268bce2a088fd37007ef50 180 Gene3D G3DSA:3.40.30.10 30 178 5.2E-29 T 29-03-2018 THSYN_RS22570 95e2c565fa268bce2a088fd37007ef50 180 ProSitePatterns PS00194 Thioredoxin family active site. 68 86 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THSYN_RS22570 95e2c565fa268bce2a088fd37007ef50 180 SUPERFAMILY SSF52833 43 174 2.87E-33 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS22570 95e2c565fa268bce2a088fd37007ef50 180 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 10 175 2.9E-54 T 29-03-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 THSYN_RS24460 3c2c784a09ca9edcdf08d50973f83688 210 SMART SM00650 56 190 0.0028 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 THSYN_RS24460 3c2c784a09ca9edcdf08d50973f83688 210 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 6 165 1.7E-29 T 29-03-2018 THSYN_RS24460 3c2c784a09ca9edcdf08d50973f83688 210 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 72 99 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 THSYN_RS24460 3c2c784a09ca9edcdf08d50973f83688 210 SUPERFAMILY SSF53335 1 192 4.26E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS24460 3c2c784a09ca9edcdf08d50973f83688 210 Gene3D G3DSA:3.40.50.150 1 198 2.8E-32 T 29-03-2018 THSYN_RS11000 8572b394bb2079ddbac18e7e64c87ceb 298 Gene3D G3DSA:3.40.190.10 10 165 7.3E-30 T 29-03-2018 THSYN_RS11000 8572b394bb2079ddbac18e7e64c87ceb 298 Gene3D G3DSA:3.40.190.10 166 298 4.9E-19 T 29-03-2018 THSYN_RS11000 8572b394bb2079ddbac18e7e64c87ceb 298 SUPERFAMILY SSF53850 1 269 1.79E-64 T 29-03-2018 THSYN_RS11000 8572b394bb2079ddbac18e7e64c87ceb 298 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 267 5.1E-50 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS11000 8572b394bb2079ddbac18e7e64c87ceb 298 SMART SM00062 37 269 3.2E-64 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS13770 e709bd93e8ebcf22e4c23d6e63e494db 107 Gene3D G3DSA:3.30.460.10 5 106 5.5E-14 T 29-03-2018 THSYN_RS13770 e709bd93e8ebcf22e4c23d6e63e494db 107 SUPERFAMILY SSF81301 8 105 9.56E-15 T 29-03-2018 THSYN_RS13770 e709bd93e8ebcf22e4c23d6e63e494db 107 Pfam PF01909 Nucleotidyltransferase domain 21 88 2.8E-6 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS10435 b67dc2cfbd50fbe851fe9a94a1b4e16c 297 Gene3D G3DSA:3.40.50.620 66 214 2.3E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS10435 b67dc2cfbd50fbe851fe9a94a1b4e16c 297 Pfam PF02698 DUF218 domain 77 242 5.2E-22 T 29-03-2018 IPR003848 Domain of unknown function DUF218 THSYN_RS07175 6edab13b70690f08cd0ec13e9a53f758 291 Pfam PF11103 Protein of unknown function (DUF2887) 3 205 4.6E-27 T 29-03-2018 IPR022573 Protein of unknown function DUF2887 THSYN_RS07175 6edab13b70690f08cd0ec13e9a53f758 291 Pfam PF14261 Domain of unknown function (DUF4351) 230 288 1.2E-19 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS13685 b72cfbf271db9ff04b7ad48d0ba8955a 235 SUPERFAMILY SSF53067 3 101 2.59E-26 T 29-03-2018 THSYN_RS13685 b72cfbf271db9ff04b7ad48d0ba8955a 235 Gene3D G3DSA:3.30.420.40 1 138 1.7E-35 T 29-03-2018 THSYN_RS13685 b72cfbf271db9ff04b7ad48d0ba8955a 235 Pfam PF00814 Glycoprotease family 28 140 2.9E-27 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THSYN_RS13685 b72cfbf271db9ff04b7ad48d0ba8955a 235 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 218 2.1E-53 T 29-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 THSYN_RS13685 b72cfbf271db9ff04b7ad48d0ba8955a 235 SUPERFAMILY SSF53067 110 216 9.97E-19 T 29-03-2018 THSYN_RS04895 74832da93ae1245974ddf01fe9e57be6 126 SUPERFAMILY SSF81301 34 121 5.45E-16 T 29-03-2018 THSYN_RS04895 74832da93ae1245974ddf01fe9e57be6 126 Gene3D G3DSA:3.30.460.10 21 121 1.9E-14 T 29-03-2018 THSYN_RS04895 74832da93ae1245974ddf01fe9e57be6 126 Pfam PF01909 Nucleotidyltransferase domain 48 105 8.9E-7 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS23620 d66b69305d6992246c0cd8f79fe36e67 138 Gene3D G3DSA:3.40.50.1110 3 137 1.3E-15 T 29-03-2018 THSYN_RS10360 8211d9c096956e60de6e0d7b6c351d0e 228 SUPERFAMILY SSF52172 1 184 1.39E-43 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS10360 8211d9c096956e60de6e0d7b6c351d0e 228 SMART SM00862 149 224 6.5E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS10360 8211d9c096956e60de6e0d7b6c351d0e 228 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 3 225 1.8E-103 T 29-03-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 THSYN_RS10360 8211d9c096956e60de6e0d7b6c351d0e 228 SMART SM00448 2 115 5.7E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS10360 8211d9c096956e60de6e0d7b6c351d0e 228 Gene3D G3DSA:1.10.10.10 124 228 8.3E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS10360 8211d9c096956e60de6e0d7b6c351d0e 228 Gene3D G3DSA:3.40.50.2300 1 123 8.9E-38 T 29-03-2018 THSYN_RS10360 8211d9c096956e60de6e0d7b6c351d0e 228 Pfam PF00072 Response regulator receiver domain 4 116 7.5E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS10360 8211d9c096956e60de6e0d7b6c351d0e 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 2.7E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS26180 ef3ee2764686f15b05f9abe892b016ee 867 SUPERFAMILY SSF52540 86 162 4.03E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26180 ef3ee2764686f15b05f9abe892b016ee 867 SUPERFAMILY SSF52540 192 222 4.03E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26180 ef3ee2764686f15b05f9abe892b016ee 867 SUPERFAMILY SSF52540 496 533 4.03E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26180 ef3ee2764686f15b05f9abe892b016ee 867 SUPERFAMILY SSF52540 573 697 4.03E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26180 ef3ee2764686f15b05f9abe892b016ee 867 Pfam PF13166 AAA domain 384 701 1.0E-14 T 29-03-2018 IPR026866 Protein CR006, P-loop domain THSYN_RS26180 ef3ee2764686f15b05f9abe892b016ee 867 Gene3D G3DSA:3.40.50.300 75 700 1.8E-22 T 29-03-2018 THSYN_RS08140 a0d4bd9c36c4a1857dfd9c18d55ec55f 952 SUPERFAMILY SSF52540 246 403 1.84E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08140 a0d4bd9c36c4a1857dfd9c18d55ec55f 952 SUPERFAMILY SSF52540 38 83 1.84E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08140 a0d4bd9c36c4a1857dfd9c18d55ec55f 952 SUPERFAMILY SSF52540 111 219 1.84E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08140 a0d4bd9c36c4a1857dfd9c18d55ec55f 952 Gene3D G3DSA:3.40.50.300 2 215 5.3E-11 T 29-03-2018 THSYN_RS08140 a0d4bd9c36c4a1857dfd9c18d55ec55f 952 SUPERFAMILY SSF109604 773 880 1.2E-5 T 29-03-2018 THSYN_RS08140 a0d4bd9c36c4a1857dfd9c18d55ec55f 952 TIGRFAM TIGR02621 cas3_GSU0051: CRISPR-associated helicase Cas3, subtype Dpsyc 2 585 4.1E-103 T 29-03-2018 IPR013444 Helicase Cas3, CRISPR-associated, Anaes-subtype THSYN_RS08140 a0d4bd9c36c4a1857dfd9c18d55ec55f 952 Pfam PF00271 Helicase conserved C-terminal domain 275 394 1.2E-4 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS08140 a0d4bd9c36c4a1857dfd9c18d55ec55f 952 Pfam PF04851 Type III restriction enzyme, res subunit 36 215 6.1E-7 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS08140 a0d4bd9c36c4a1857dfd9c18d55ec55f 952 Gene3D G3DSA:1.10.3210.10 757 932 7.4E-6 T 29-03-2018 THSYN_RS08140 a0d4bd9c36c4a1857dfd9c18d55ec55f 952 Gene3D G3DSA:3.40.50.300 262 433 1.4E-12 T 29-03-2018 THSYN_RS08140 a0d4bd9c36c4a1857dfd9c18d55ec55f 952 SMART SM00490 300 394 2.2E-5 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS08140 a0d4bd9c36c4a1857dfd9c18d55ec55f 952 SMART SM00487 11 245 0.0045 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS05815 8203b3a7d5f23e73aa3aecee96dcc19e 346 Gene3D G3DSA:3.40.190.10 24 170 1.7E-22 T 29-03-2018 THSYN_RS05815 8203b3a7d5f23e73aa3aecee96dcc19e 346 SUPERFAMILY SSF53850 25 336 7.6E-66 T 29-03-2018 THSYN_RS05815 8203b3a7d5f23e73aa3aecee96dcc19e 346 Pfam PF12849 PBP superfamily domain 19 307 6.8E-43 T 29-03-2018 IPR024370 PBP domain THSYN_RS05815 8203b3a7d5f23e73aa3aecee96dcc19e 346 Gene3D G3DSA:3.40.190.10 180 338 2.1E-18 T 29-03-2018 THSYN_RS16330 ecd04ff93276bbe7db0797d51a3fc868 132 Pfam PF05685 Putative restriction endonuclease 6 113 2.6E-17 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS16330 ecd04ff93276bbe7db0797d51a3fc868 132 SUPERFAMILY SSF52980 5 113 2.09E-9 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS16330 ecd04ff93276bbe7db0797d51a3fc868 132 Gene3D G3DSA:3.90.1570.10 2 126 6.2E-24 T 29-03-2018 THSYN_RS18465 ca2201655a4ba9937d7f8cccec52bdf1 320 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 193 299 6.1E-12 T 29-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein THSYN_RS18465 ca2201655a4ba9937d7f8cccec52bdf1 320 Pfam PF13244 Domain of unknown function (DUF4040) 13 78 1.8E-13 T 29-03-2018 IPR025383 Domain of unknown function DUF4040 THSYN_RS26715 37b19fa8e8a73f3f262e9cb746c1acd7 240 ProSitePatterns PS01318 TsaA-like domain signature. 87 98 - T 29-03-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site THSYN_RS26715 37b19fa8e8a73f3f262e9cb746c1acd7 240 Pfam PF01980 Uncharacterised protein family UPF0066 19 143 4.7E-40 T 29-03-2018 IPR023370 TsaA-like domain THSYN_RS26715 37b19fa8e8a73f3f262e9cb746c1acd7 240 Gene3D G3DSA:2.40.30.70 4 149 7.8E-52 T 29-03-2018 IPR023370 TsaA-like domain THSYN_RS26715 37b19fa8e8a73f3f262e9cb746c1acd7 240 Gene3D G3DSA:3.30.2310.10 150 233 2.8E-16 T 29-03-2018 THSYN_RS26715 37b19fa8e8a73f3f262e9cb746c1acd7 240 SUPERFAMILY SSF118196 1 232 1.24E-72 T 29-03-2018 IPR023370 TsaA-like domain THSYN_RS26715 37b19fa8e8a73f3f262e9cb746c1acd7 240 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 3 146 1.5E-45 T 29-03-2018 IPR023370 TsaA-like domain THSYN_RS02080 93d64c34c92506e94ec0a3a3f59a63b4 176 Pfam PF08282 haloacid dehalogenase-like hydrolase 76 143 2.6E-7 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS02080 93d64c34c92506e94ec0a3a3f59a63b4 176 PIRSF PIRSF006118 1 173 3.8E-69 T 29-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THSYN_RS02080 93d64c34c92506e94ec0a3a3f59a63b4 176 Gene3D G3DSA:3.40.50.1000 2 172 1.1E-30 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS02080 93d64c34c92506e94ec0a3a3f59a63b4 176 SUPERFAMILY SSF56784 7 169 2.84E-43 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS02080 93d64c34c92506e94ec0a3a3f59a63b4 176 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 11 163 3.3E-52 T 29-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THSYN_RS26700 9eeae694a02d64978b21feecf27476ef 510 SUPERFAMILY SSF52540 264 405 5.73E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26700 9eeae694a02d64978b21feecf27476ef 510 Pfam PF01926 50S ribosome-binding GTPase 277 371 1.4E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS26700 9eeae694a02d64978b21feecf27476ef 510 Gene3D G3DSA:3.40.50.300 249 495 7.3E-21 T 29-03-2018 THSYN_RS29165 1fd4d9772eb0a07ff4c57e81562a67b9 518 SUPERFAMILY SSF50615 10 99 2.35E-25 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS29165 1fd4d9772eb0a07ff4c57e81562a67b9 518 Gene3D G3DSA:2.40.30.20 3 87 3.0E-29 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29165 1fd4d9772eb0a07ff4c57e81562a67b9 518 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 154 380 4.3E-73 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS29165 1fd4d9772eb0a07ff4c57e81562a67b9 518 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 387 512 1.0E-44 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29165 1fd4d9772eb0a07ff4c57e81562a67b9 518 Gene3D G3DSA:3.40.50.300 88 380 6.4E-114 T 29-03-2018 THSYN_RS29165 1fd4d9772eb0a07ff4c57e81562a67b9 518 SUPERFAMILY SSF52540 101 386 6.44E-94 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29165 1fd4d9772eb0a07ff4c57e81562a67b9 518 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 97 1.7E-10 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS29165 1fd4d9772eb0a07ff4c57e81562a67b9 518 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 516 2.9E-244 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29165 1fd4d9772eb0a07ff4c57e81562a67b9 518 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 371 380 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS29165 1fd4d9772eb0a07ff4c57e81562a67b9 518 Gene3D G3DSA:1.20.150.20 389 515 8.1E-46 T 29-03-2018 THSYN_RS29165 1fd4d9772eb0a07ff4c57e81562a67b9 518 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 517 49.131 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29165 1fd4d9772eb0a07ff4c57e81562a67b9 518 SUPERFAMILY SSF47917 388 515 6.02E-46 T 29-03-2018 THSYN_RS27330 19021e065dc6b25e2899cbffa80fc8af 69 Gene3D G3DSA:1.10.10.10 6 65 1.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS27330 19021e065dc6b25e2899cbffa80fc8af 69 SUPERFAMILY SSF46689 4 56 1.97E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS27330 19021e065dc6b25e2899cbffa80fc8af 69 Pfam PF04255 Protein of unknown function (DUF433) 6 54 2.2E-17 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS00175 21eca414cfbf3f49d27d23d0eebd1096 218 Pfam PF07484 Phage Tail Collar Domain 36 92 1.5E-21 T 29-03-2018 IPR011083 Phage tail collar domain THSYN_RS00175 21eca414cfbf3f49d27d23d0eebd1096 218 Gene3D G3DSA:4.10.1070.10 85 194 5.5E-6 T 29-03-2018 THSYN_RS00175 21eca414cfbf3f49d27d23d0eebd1096 218 SUPERFAMILY SSF88874 30 212 8.76E-42 T 29-03-2018 THSYN_RS00175 21eca414cfbf3f49d27d23d0eebd1096 218 Gene3D G3DSA:3.90.1340.10 25 84 2.7E-18 T 29-03-2018 IPR011083 Phage tail collar domain THSYN_RS07795 a181c30aebf3e8fbe02ca35e161511f2 531 Gene3D G3DSA:3.40.50.300 319 531 1.5E-50 T 29-03-2018 THSYN_RS07795 a181c30aebf3e8fbe02ca35e161511f2 531 SUPERFAMILY SSF52540 298 525 3.66E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07795 a181c30aebf3e8fbe02ca35e161511f2 531 Gene3D G3DSA:3.40.50.300 2 285 1.7E-50 T 29-03-2018 THSYN_RS07795 a181c30aebf3e8fbe02ca35e161511f2 531 Pfam PF00005 ABC transporter 337 467 3.3E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS07795 a181c30aebf3e8fbe02ca35e161511f2 531 Pfam PF00005 ABC transporter 18 184 8.7E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS07795 a181c30aebf3e8fbe02ca35e161511f2 531 SMART SM00382 26 238 4.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS07795 a181c30aebf3e8fbe02ca35e161511f2 531 SMART SM00382 344 512 2.0E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS07795 a181c30aebf3e8fbe02ca35e161511f2 531 SUPERFAMILY SSF52540 6 237 5.41E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07795 a181c30aebf3e8fbe02ca35e161511f2 531 Pfam PF12848 ABC transporter 224 309 1.8E-21 T 29-03-2018 IPR032781 ABC-transporter extension domain THSYN_RS30875 a85806f35b73f988cd0f28fbc10c5489 361 PRINTS PR01486 Bacterial phospholipase A1 protein signature 150 167 2.0E-33 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 THSYN_RS30875 a85806f35b73f988cd0f28fbc10c5489 361 PRINTS PR01486 Bacterial phospholipase A1 protein signature 194 213 2.0E-33 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 THSYN_RS30875 a85806f35b73f988cd0f28fbc10c5489 361 PRINTS PR01486 Bacterial phospholipase A1 protein signature 274 292 2.0E-33 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 THSYN_RS30875 a85806f35b73f988cd0f28fbc10c5489 361 PRINTS PR01486 Bacterial phospholipase A1 protein signature 330 350 2.0E-33 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 THSYN_RS30875 a85806f35b73f988cd0f28fbc10c5489 361 PRINTS PR01486 Bacterial phospholipase A1 protein signature 239 257 2.0E-33 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 THSYN_RS30875 a85806f35b73f988cd0f28fbc10c5489 361 PRINTS PR01486 Bacterial phospholipase A1 protein signature 307 324 2.0E-33 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 THSYN_RS30875 a85806f35b73f988cd0f28fbc10c5489 361 PRINTS PR01486 Bacterial phospholipase A1 protein signature 224 238 2.0E-33 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 THSYN_RS30875 a85806f35b73f988cd0f28fbc10c5489 361 Pfam PF02253 Phospholipase A1 111 357 1.8E-85 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 THSYN_RS30875 a85806f35b73f988cd0f28fbc10c5489 361 Gene3D G3DSA:2.40.230.10 107 361 4.3E-82 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 THSYN_RS30875 a85806f35b73f988cd0f28fbc10c5489 361 SUPERFAMILY SSF56931 111 360 4.18E-80 T 29-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 THSYN_RS25305 f8122c497dad54c7f243a6119f0bd84b 112 TIGRFAM TIGR04176 MarR_EPS: EPS-associated transcriptional regulator, MarR family 2 100 3.0E-44 T 29-03-2018 IPR026433 EPS-associated transcriptional regulator, MarR family THSYN_RS25305 f8122c497dad54c7f243a6119f0bd84b 112 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 45 4.7E-10 T 29-03-2018 THSYN_RS25305 f8122c497dad54c7f243a6119f0bd84b 112 SUPERFAMILY SSF46785 2 96 3.0E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25305 f8122c497dad54c7f243a6119f0bd84b 112 Gene3D G3DSA:1.10.10.10 1 101 4.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25315 f8122c497dad54c7f243a6119f0bd84b 112 TIGRFAM TIGR04176 MarR_EPS: EPS-associated transcriptional regulator, MarR family 2 100 3.0E-44 T 29-03-2018 IPR026433 EPS-associated transcriptional regulator, MarR family THSYN_RS25315 f8122c497dad54c7f243a6119f0bd84b 112 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 45 4.7E-10 T 29-03-2018 THSYN_RS25315 f8122c497dad54c7f243a6119f0bd84b 112 SUPERFAMILY SSF46785 2 96 3.0E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25315 f8122c497dad54c7f243a6119f0bd84b 112 Gene3D G3DSA:1.10.10.10 1 101 4.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS22075 c8835e164b87e2eca8bd53a33272d9b9 290 Pfam PF00483 Nucleotidyl transferase 11 268 4.7E-29 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THSYN_RS22075 c8835e164b87e2eca8bd53a33272d9b9 290 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 266 5.9E-113 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 THSYN_RS22075 c8835e164b87e2eca8bd53a33272d9b9 290 SUPERFAMILY SSF53448 1 270 2.19E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22075 c8835e164b87e2eca8bd53a33272d9b9 290 Gene3D G3DSA:3.90.550.10 1 279 1.8E-60 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS12195 6767e8196f7e410aff4183494783b4ae 152 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 37 138 1.2E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS12195 6767e8196f7e410aff4183494783b4ae 152 SMART SM00091 14 83 4.1E-4 T 29-03-2018 IPR000014 PAS domain THSYN_RS12195 6767e8196f7e410aff4183494783b4ae 152 Pfam PF13426 PAS domain 26 130 2.5E-20 T 29-03-2018 IPR000014 PAS domain THSYN_RS12195 6767e8196f7e410aff4183494783b4ae 152 Gene3D G3DSA:3.30.450.20 15 146 4.4E-27 T 29-03-2018 THSYN_RS12195 6767e8196f7e410aff4183494783b4ae 152 SMART SM00086 89 131 3.2E-11 T 29-03-2018 IPR001610 PAC motif THSYN_RS12195 6767e8196f7e410aff4183494783b4ae 152 SUPERFAMILY SSF55785 19 129 2.9E-25 T 29-03-2018 IPR000014 PAS domain THSYN_RS23040 e39173fb586be52641ae542543761bea 1316 SUPERFAMILY SSF56436 1071 1308 3.01E-55 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS23040 e39173fb586be52641ae542543761bea 1316 Gene3D G3DSA:3.90.1580.10 1132 1315 5.3E-44 T 29-03-2018 THSYN_RS23040 e39173fb586be52641ae542543761bea 1316 Gene3D G3DSA:3.90.1580.10 1063 1131 6.6E-6 T 29-03-2018 THSYN_RS23040 e39173fb586be52641ae542543761bea 1316 Pfam PF03781 Sulfatase-modifying factor enzyme 1 1073 1308 1.3E-40 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS04670 90d5523713ad5e279b2551c4a71f2fcd 346 SUPERFAMILY SSF52540 2 213 4.03E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04670 90d5523713ad5e279b2551c4a71f2fcd 346 Pfam PF00005 ABC transporter 20 164 1.9E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS04670 90d5523713ad5e279b2551c4a71f2fcd 346 Gene3D G3DSA:3.40.50.300 1 254 4.8E-32 T 29-03-2018 THSYN_RS04670 90d5523713ad5e279b2551c4a71f2fcd 346 SMART SM00382 26 215 1.3E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS26890 d62eee0ed20a09484f2076d3285c8bfb 170 Gene3D G3DSA:1.20.1550.10 3 165 6.6E-35 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain THSYN_RS26890 d62eee0ed20a09484f2076d3285c8bfb 170 Pfam PF02600 Disulfide bond formation protein DsbB 7 157 1.2E-30 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 THSYN_RS26890 d62eee0ed20a09484f2076d3285c8bfb 170 SUPERFAMILY SSF158442 10 158 2.35E-29 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain THSYN_RS16800 ffcedd1610f38f29a7dc8511ad887a1b 306 Gene3D G3DSA:1.10.10.60 228 260 0.0073 T 29-03-2018 THSYN_RS16800 ffcedd1610f38f29a7dc8511ad887a1b 306 Pfam PF11103 Protein of unknown function (DUF2887) 3 204 3.4E-24 T 29-03-2018 IPR022573 Protein of unknown function DUF2887 THSYN_RS16800 ffcedd1610f38f29a7dc8511ad887a1b 306 Pfam PF14261 Domain of unknown function (DUF4351) 245 303 1.2E-17 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS10195 896acfa757ece707ca98f17c43f8fd19 335 SUPERFAMILY SSF56059 124 313 3.98E-57 T 29-03-2018 THSYN_RS10195 896acfa757ece707ca98f17c43f8fd19 335 Gene3D G3DSA:3.40.50.20 3 130 2.7E-49 T 29-03-2018 THSYN_RS10195 896acfa757ece707ca98f17c43f8fd19 335 TIGRFAM TIGR01380 glut_syn: glutathione synthase 4 312 8.4E-134 T 29-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 THSYN_RS10195 896acfa757ece707ca98f17c43f8fd19 335 Gene3D G3DSA:3.30.1490.20 139 192 8.7E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS10195 896acfa757ece707ca98f17c43f8fd19 335 SUPERFAMILY SSF52440 3 123 1.12E-43 T 29-03-2018 IPR016185 Pre-ATP-grasp domain THSYN_RS10195 896acfa757ece707ca98f17c43f8fd19 335 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 125 297 4.3E-75 T 29-03-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 THSYN_RS10195 896acfa757ece707ca98f17c43f8fd19 335 Gene3D G3DSA:3.30.470.20 193 301 2.1E-12 T 29-03-2018 THSYN_RS10195 896acfa757ece707ca98f17c43f8fd19 335 Hamap MF_00162 Glutathione synthetase [gshB]. 1 317 167.328 T 29-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 THSYN_RS10195 896acfa757ece707ca98f17c43f8fd19 335 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 4 121 1.0E-44 T 29-03-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 THSYN_RS23395 ddf5fefe4aa37d97022842a990f486cc 326 Pfam PF00849 RNA pseudouridylate synthase 96 245 1.4E-30 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS23395 ddf5fefe4aa37d97022842a990f486cc 326 SUPERFAMILY SSF55174 21 71 6.39E-7 T 29-03-2018 THSYN_RS23395 ddf5fefe4aa37d97022842a990f486cc 326 Gene3D G3DSA:3.30.2350.10 87 319 1.3E-66 T 29-03-2018 THSYN_RS23395 ddf5fefe4aa37d97022842a990f486cc 326 Gene3D G3DSA:3.10.290.10 6 76 1.7E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS23395 ddf5fefe4aa37d97022842a990f486cc 326 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS23395 ddf5fefe4aa37d97022842a990f486cc 326 SUPERFAMILY SSF55120 81 318 3.29E-76 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS23395 ddf5fefe4aa37d97022842a990f486cc 326 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 19 315 5.8E-90 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS12440 34f2b2739add2ec049f5458acdfca576 258 Gene3D G3DSA:3.90.226.10 1 216 1.6E-54 T 29-03-2018 THSYN_RS12440 34f2b2739add2ec049f5458acdfca576 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 6 257 3.9E-40 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THSYN_RS12440 34f2b2739add2ec049f5458acdfca576 258 SUPERFAMILY SSF52096 3 258 8.44E-68 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS12440 34f2b2739add2ec049f5458acdfca576 258 Gene3D G3DSA:1.10.12.10 217 258 6.9E-9 T 29-03-2018 IPR014748 Crontonase, C-terminal THSYN_RS11515 8c5aeefc9a611400a9e31cc2630c8da9 583 Gene3D G3DSA:1.25.40.10 363 576 1.5E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS11515 8c5aeefc9a611400a9e31cc2630c8da9 583 Gene3D G3DSA:1.10.510.10 153 351 1.1E-34 T 29-03-2018 THSYN_RS11515 8c5aeefc9a611400a9e31cc2630c8da9 583 Pfam PF00069 Protein kinase domain 69 315 5.6E-35 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS11515 8c5aeefc9a611400a9e31cc2630c8da9 583 SUPERFAMILY SSF56112 66 326 5.19E-57 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS11515 8c5aeefc9a611400a9e31cc2630c8da9 583 Gene3D G3DSA:3.30.200.20 62 152 3.4E-18 T 29-03-2018 THSYN_RS16745 91748967dd8e952a61a0811da3fe59b5 86 Gene3D G3DSA:1.10.1220.10 1 41 3.3E-7 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS16745 91748967dd8e952a61a0811da3fe59b5 86 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 34 7.5E-7 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 THSYN_RS02975 50e0ed487a80aaeb2fae382d95d3b0a2 275 Gene3D G3DSA:3.20.20.370 65 274 9.8E-43 T 29-03-2018 THSYN_RS02975 50e0ed487a80aaeb2fae382d95d3b0a2 275 SUPERFAMILY SSF88713 56 271 4.45E-48 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS02975 50e0ed487a80aaeb2fae382d95d3b0a2 275 Pfam PF01522 Polysaccharide deacetylase 78 194 1.3E-23 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 THSYN_RS02150 bdd367bb7b9284c0c3580e49b1893fa0 193 Pfam PF03413 Peptidase propeptide and YPEB domain 124 190 5.6E-7 T 29-03-2018 IPR025711 PepSY domain THSYN_RS02150 bdd367bb7b9284c0c3580e49b1893fa0 193 Gene3D G3DSA:3.10.450.40 124 191 7.0E-7 T 29-03-2018 THSYN_RS15730 0913e647a3345f67b929fede6e6a52a6 269 SUPERFAMILY SSF52540 2 268 2.32E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15730 0913e647a3345f67b929fede6e6a52a6 269 Gene3D G3DSA:3.40.50.300 1 254 9.1E-53 T 29-03-2018 THSYN_RS15730 0913e647a3345f67b929fede6e6a52a6 269 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 267 3.4E-109 T 29-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 THSYN_RS15730 0913e647a3345f67b929fede6e6a52a6 269 Pfam PF13614 AAA domain 3 164 6.1E-22 T 29-03-2018 IPR025669 AAA domain THSYN_RS15730 0913e647a3345f67b929fede6e6a52a6 269 PIRSF PIRSF003092 1 269 8.7E-90 T 29-03-2018 IPR025501 ATP binding protein MinD THSYN_RS20290 e3da675cd6f37029aa80a05615124b09 403 Gene3D G3DSA:3.40.640.10 13 256 3.4E-55 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS20290 e3da675cd6f37029aa80a05615124b09 403 Gene3D G3DSA:3.90.1150.10 264 382 3.1E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS20290 e3da675cd6f37029aa80a05615124b09 403 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 194 213 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site THSYN_RS20290 e3da675cd6f37029aa80a05615124b09 403 TIGRFAM TIGR03402 FeS_nifS: cysteine desulfurase NifS 5 384 3.4E-193 T 29-03-2018 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal GO:0006520|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 THSYN_RS20290 e3da675cd6f37029aa80a05615124b09 403 SUPERFAMILY SSF53383 5 375 2.39E-103 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS20290 e3da675cd6f37029aa80a05615124b09 403 PIRSF PIRSF005572 2 382 4.2E-128 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 THSYN_RS20290 e3da675cd6f37029aa80a05615124b09 403 Pfam PF00266 Aminotransferase class-V 5 366 1.1E-94 T 29-03-2018 IPR000192 Aminotransferase class V domain THSYN_RS14260 18476e1f70f0e3b605f2c6c72afc1f52 76 SUPERFAMILY SSF46689 15 68 1.65E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS14260 18476e1f70f0e3b605f2c6c72afc1f52 76 Pfam PF02954 Bacterial regulatory protein, Fis family 30 66 6.6E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THSYN_RS14260 18476e1f70f0e3b605f2c6c72afc1f52 76 Gene3D G3DSA:1.10.10.60 4 72 6.1E-12 T 29-03-2018 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 SMART SM00493 1 101 6.9E-33 T 29-03-2018 IPR006171 TOPRIM domain THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Hamap MF_00952 DNA topoisomerase 1 [topA]. 1 697 55.064 T 29-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Gene3D G3DSA:1.10.460.10 137 330 3.4E-46 T 29-03-2018 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Gene3D G3DSA:1.10.460.10 462 577 1.8E-25 T 29-03-2018 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Gene3D G3DSA:3.30.65.10 675 719 1.0E-10 T 29-03-2018 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Gene3D G3DSA:3.30.65.10 630 674 1.8E-16 T 29-03-2018 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Gene3D G3DSA:3.30.65.10 578 629 8.9E-18 T 29-03-2018 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Gene3D G3DSA:3.30.65.10 720 762 0.064 T 29-03-2018 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 SMART SM00436 106 194 3.9E-50 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 SUPERFAMILY SSF56712 1 601 1.24E-191 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 287 309 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 3 623 9.8E-243 T 29-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 SMART SM00437 250 522 3.9E-111 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Pfam PF01131 DNA topoisomerase 131 559 1.5E-129 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 589 624 2.4E-16 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 639 675 7.8E-14 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 681 719 9.4E-12 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Pfam PF01751 Toprim domain 3 115 2.4E-28 T 29-03-2018 IPR006171 TOPRIM domain THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Gene3D G3DSA:2.70.20.10 332 461 1.3E-38 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 75 88 8.3E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 164 182 8.3E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 485 499 8.3E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 378 394 8.3E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 300 309 8.3E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 SUPERFAMILY SSF57783 590 625 9.18E-12 T 29-03-2018 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 Gene3D G3DSA:3.40.50.140 1 131 2.9E-40 T 29-03-2018 THSYN_RS20580 7d414b3932562771b0092810c857f29e 768 SUPERFAMILY SSF57783 636 676 1.53E-11 T 29-03-2018 THSYN_RS12700 2a72402f57a8cce21425e0436773c74f 128 Pfam PF01042 Endoribonuclease L-PSP 9 125 3.0E-41 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family THSYN_RS12700 2a72402f57a8cce21425e0436773c74f 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 125 1.5E-49 T 29-03-2018 IPR006056 RidA family THSYN_RS12700 2a72402f57a8cce21425e0436773c74f 128 SUPERFAMILY SSF55298 1 127 8.17E-47 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THSYN_RS12700 2a72402f57a8cce21425e0436773c74f 128 Gene3D G3DSA:3.30.1330.40 1 128 9.1E-49 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THSYN_RS12700 2a72402f57a8cce21425e0436773c74f 128 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 102 120 - T 29-03-2018 IPR019897 RidA, conserved site THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Gene3D G3DSA:1.10.10.10 385 446 1.7E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Gene3D G3DSA:1.10.10.10 296 360 4.5E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Gene3D G3DSA:1.10.10.10 70 126 1.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Gene3D G3DSA:1.10.10.10 127 192 3.6E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Gene3D G3DSA:1.10.10.10 218 270 5.9E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Pfam PF13424 Tetratricopeptide repeat 271 342 3.5E-19 T 29-03-2018 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Pfam PF13424 Tetratricopeptide repeat 100 174 1.2E-20 T 29-03-2018 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Pfam PF13424 Tetratricopeptide repeat 189 258 4.8E-21 T 29-03-2018 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Pfam PF13424 Tetratricopeptide repeat 357 426 8.1E-18 T 29-03-2018 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 PRINTS PR00381 Kinesin light chain signature 225 245 8.5E-14 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 PRINTS PR00381 Kinesin light chain signature 260 281 8.5E-14 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 PRINTS PR00381 Kinesin light chain signature 94 113 8.5E-14 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 PRINTS PR00381 Kinesin light chain signature 181 198 8.5E-14 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 PRINTS PR00381 Kinesin light chain signature 116 134 8.5E-14 T 29-03-2018 IPR002151 Kinesin light chain GO:0003777|GO:0005871 Reactome: R-HSA-2132295|Reactome: R-HSA-5625970|Reactome: R-HSA-6811434|Reactome: R-HSA-983189 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Gene3D G3DSA:1.20.58.280 361 384 2.1E-5 T 29-03-2018 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Gene3D G3DSA:1.20.58.280 193 217 6.7E-8 T 29-03-2018 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 SUPERFAMILY SSF48452 95 449 9.01E-31 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Pfam PF12770 CHAT domain 696 1106 3.2E-51 T 29-03-2018 IPR024983 CHAT domain THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Gene3D G3DSA:3.40.50.1460 850 1106 1.5E-19 T 29-03-2018 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 Gene3D G3DSA:1.25.40.10 271 295 4.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 SMART SM00028 185 218 0.63 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 SMART SM00028 395 428 0.058 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 SMART SM00028 227 260 0.0083 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 SMART SM00028 353 386 69.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 SMART SM00028 101 134 0.05 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 SMART SM00028 143 176 0.26 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 SMART SM00028 311 344 0.78 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS23590 7cbc2373f73b29ee10668c2cce2d83a3 1109 SMART SM00028 269 302 0.46 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS26230 6f116b3a5223b88601a7818f723e2cf5 121 Pfam PF04328 Selenoprotein, putative 58 121 9.2E-20 T 29-03-2018 IPR007423 Selenoprotein, putative THSYN_RS09870 15624cd8ab840b690a0cca205604cb29 226 Pfam PF01863 Protein of unknown function DUF45 13 218 1.5E-50 T 29-03-2018 IPR002725 Protein of unknown function DUF45 THSYN_RS04160 dec863d19cf07c9cafae884a89372578 163 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 2 160 1.0E-45 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THSYN_RS04160 dec863d19cf07c9cafae884a89372578 163 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 36 53 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 THSYN_RS04160 dec863d19cf07c9cafae884a89372578 163 PIRSF PIRSF001467 1 162 9.1E-25 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 THSYN_RS04160 dec863d19cf07c9cafae884a89372578 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 15 30 1.3E-10 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THSYN_RS04160 dec863d19cf07c9cafae884a89372578 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 116 131 1.3E-10 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THSYN_RS04160 dec863d19cf07c9cafae884a89372578 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 41 53 1.3E-10 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THSYN_RS04160 dec863d19cf07c9cafae884a89372578 163 Gene3D G3DSA:2.40.100.10 1 163 8.1E-47 T 29-03-2018 IPR029000 Cyclophilin-like domain THSYN_RS04160 dec863d19cf07c9cafae884a89372578 163 SUPERFAMILY SSF50891 2 160 1.33E-55 T 29-03-2018 IPR029000 Cyclophilin-like domain THSYN_RS09165 1cbee6b78c1216e31fcc97d29d09755b 444 Gene3D G3DSA:3.40.50.300 46 114 1.3E-4 T 29-03-2018 THSYN_RS09165 1cbee6b78c1216e31fcc97d29d09755b 444 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 163 3.6E-7 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS09165 1cbee6b78c1216e31fcc97d29d09755b 444 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 444 1.0E-207 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 THSYN_RS09165 1cbee6b78c1216e31fcc97d29d09755b 444 Pfam PF07724 AAA domain (Cdc48 subfamily) 190 330 1.8E-39 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS09165 1cbee6b78c1216e31fcc97d29d09755b 444 SMART SM00382 49 333 7.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS09165 1cbee6b78c1216e31fcc97d29d09755b 444 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 336 407 1.6E-6 T 29-03-2018 IPR019489 Clp ATPase, C-terminal THSYN_RS09165 1cbee6b78c1216e31fcc97d29d09755b 444 SUPERFAMILY SSF52540 4 442 9.98E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09165 1cbee6b78c1216e31fcc97d29d09755b 444 Gene3D G3DSA:1.10.8.10 115 200 2.2E-25 T 29-03-2018 THSYN_RS09165 1cbee6b78c1216e31fcc97d29d09755b 444 Gene3D G3DSA:1.10.8.60 336 432 6.6E-30 T 29-03-2018 THSYN_RS09165 1cbee6b78c1216e31fcc97d29d09755b 444 Gene3D G3DSA:1.10.8.10 201 243 4.8E-15 T 29-03-2018 THSYN_RS09165 1cbee6b78c1216e31fcc97d29d09755b 444 SMART SM01086 336 432 2.1E-22 T 29-03-2018 IPR019489 Clp ATPase, C-terminal THSYN_RS09165 1cbee6b78c1216e31fcc97d29d09755b 444 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 444 42.51 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 THSYN_RS17370 30264107b84ccc6ed025e266a6d910b4 437 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 4 435 41.033 T 29-03-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 THSYN_RS17370 30264107b84ccc6ed025e266a6d910b4 437 SUPERFAMILY SSF51556 62 361 3.15E-101 T 29-03-2018 IPR032466 Metal-dependent hydrolase THSYN_RS17370 30264107b84ccc6ed025e266a6d910b4 437 SUPERFAMILY SSF51338 4 62 1.56E-27 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS17370 30264107b84ccc6ed025e266a6d910b4 437 SUPERFAMILY SSF51338 360 434 1.56E-27 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS17370 30264107b84ccc6ed025e266a6d910b4 437 Gene3D G3DSA:3.20.20.140 74 360 3.0E-64 T 29-03-2018 THSYN_RS17370 30264107b84ccc6ed025e266a6d910b4 437 Pfam PF01979 Amidohydrolase family 59 409 9.2E-73 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 THSYN_RS17370 30264107b84ccc6ed025e266a6d910b4 437 Gene3D G3DSA:2.30.40.10 1 73 3.0E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS32950 20490b026085795d313ca9b7d296c305 1099 SUPERFAMILY SSF52540 327 495 3.69E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS32950 20490b026085795d313ca9b7d296c305 1099 Gene3D G3DSA:3.40.50.300 331 639 2.8E-8 T 29-03-2018 THSYN_RS32950 20490b026085795d313ca9b7d296c305 1099 Pfam PF03781 Sulfatase-modifying factor enzyme 1 826 1092 5.9E-47 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS32950 20490b026085795d313ca9b7d296c305 1099 SUPERFAMILY SSF56436 826 1093 1.2E-60 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS32950 20490b026085795d313ca9b7d296c305 1099 Pfam PF05729 NACHT domain 439 517 3.9E-6 T 29-03-2018 THSYN_RS32950 20490b026085795d313ca9b7d296c305 1099 Gene3D G3DSA:3.60.21.10 1 241 2.4E-10 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS32950 20490b026085795d313ca9b7d296c305 1099 Gene3D G3DSA:3.90.1580.10 814 1099 3.8E-60 T 29-03-2018 THSYN_RS32950 20490b026085795d313ca9b7d296c305 1099 SUPERFAMILY SSF56300 1 7 5.7E-11 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS32950 20490b026085795d313ca9b7d296c305 1099 SUPERFAMILY SSF56300 52 200 5.7E-11 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS22690 fdfa8edc57639e07e0321867ec7a7855 130 TIGRFAM TIGR03012 sulf_tusD_dsrE: sulfur relay protein TusD/DsrE 2 128 4.1E-50 T 29-03-2018 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 THSYN_RS22690 fdfa8edc57639e07e0321867ec7a7855 130 SUPERFAMILY SSF75169 1 128 2.02E-41 T 29-03-2018 IPR027396 DsrEFH-like THSYN_RS22690 fdfa8edc57639e07e0321867ec7a7855 130 Gene3D G3DSA:3.40.1260.10 1 130 3.8E-32 T 29-03-2018 THSYN_RS22690 fdfa8edc57639e07e0321867ec7a7855 130 Pfam PF02635 DsrE/DsrF-like family 1 128 5.9E-30 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein THSYN_RS31345 8a0daa339aa8b4afe749c6365e7fa835 313 TIGRFAM TIGR01202 bchC: chlorophyll synthesis pathway protein BchC 3 308 3.8E-133 T 29-03-2018 IPR005903 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase GO:0016491|GO:0030494|GO:0036354|GO:0055114 THSYN_RS31345 8a0daa339aa8b4afe749c6365e7fa835 313 SUPERFAMILY SSF50129 2 152 1.89E-22 T 29-03-2018 IPR011032 GroES-like THSYN_RS31345 8a0daa339aa8b4afe749c6365e7fa835 313 SUPERFAMILY SSF51735 123 275 4.11E-9 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS31345 8a0daa339aa8b4afe749c6365e7fa835 313 Gene3D G3DSA:3.90.180.10 1 313 5.5E-30 T 29-03-2018 THSYN_RS23450 e90f13f4647234a53d395b29df1f2cee 403 Pfam PF05036 Sporulation related domain 326 395 6.3E-12 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 THSYN_RS23450 e90f13f4647234a53d395b29df1f2cee 403 SUPERFAMILY SSF110997 324 400 2.88E-12 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 THSYN_RS23450 e90f13f4647234a53d395b29df1f2cee 403 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 20 197 25.01 T 29-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 THSYN_RS23450 e90f13f4647234a53d395b29df1f2cee 403 SUPERFAMILY SSF50685 104 192 2.02E-9 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain THSYN_RS23450 e90f13f4647234a53d395b29df1f2cee 403 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 107 202 1.8E-43 T 29-03-2018 IPR012997 Rare lipoprotein A THSYN_RS23450 e90f13f4647234a53d395b29df1f2cee 403 Gene3D G3DSA:3.30.70.1070 327 398 3.4E-12 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 THSYN_RS23450 e90f13f4647234a53d395b29df1f2cee 403 Gene3D G3DSA:2.40.40.10 84 197 3.3E-24 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain THSYN_RS23450 e90f13f4647234a53d395b29df1f2cee 403 Pfam PF03330 Lytic transglycolase 106 193 1.9E-25 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain THSYN_RS06635 d97059c8456cd4cc4cab9afd13c41400 161 SUPERFAMILY SSF52980 40 130 6.97E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS06635 d97059c8456cd4cc4cab9afd13c41400 161 Gene3D G3DSA:3.90.1570.10 37 157 8.3E-17 T 29-03-2018 THSYN_RS06635 d97059c8456cd4cc4cab9afd13c41400 161 Pfam PF05685 Putative restriction endonuclease 45 126 3.0E-11 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS04600 494db4f6f87ab54238f7e0e3543816d0 234 SUPERFAMILY SSF56436 14 127 8.79E-54 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS04600 494db4f6f87ab54238f7e0e3543816d0 234 SUPERFAMILY SSF56436 185 231 8.79E-54 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS04600 494db4f6f87ab54238f7e0e3543816d0 234 Gene3D G3DSA:3.90.1580.10 3 234 1.6E-57 T 29-03-2018 THSYN_RS04600 494db4f6f87ab54238f7e0e3543816d0 234 Pfam PF03781 Sulfatase-modifying factor enzyme 1 180 230 2.5E-5 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS04600 494db4f6f87ab54238f7e0e3543816d0 234 Pfam PF03781 Sulfatase-modifying factor enzyme 1 16 147 2.3E-36 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS19000 8f112cd94e1d931f6649ee750299713a 209 Gene3D G3DSA:1.20.950.20 1 209 3.9E-32 T 29-03-2018 THSYN_RS19000 8f112cd94e1d931f6649ee750299713a 209 Pfam PF01292 Prokaryotic cytochrome b561 7 198 6.5E-19 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THSYN_RS19000 8f112cd94e1d931f6649ee750299713a 209 SUPERFAMILY SSF81342 2 208 1.1E-23 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THSYN_RS19000 8f112cd94e1d931f6649ee750299713a 209 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 161 183 1.1E-5 T 29-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 THSYN_RS19000 8f112cd94e1d931f6649ee750299713a 209 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 9 32 1.1E-5 T 29-03-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 THSYN_RS00955 62a49f7e2bcc8aba1a313cd38845fda0 617 Gene3D G3DSA:3.30.565.10 4 576 4.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00955 62a49f7e2bcc8aba1a313cd38845fda0 617 SUPERFAMILY SSF55874 36 228 1.31E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS00955 62a49f7e2bcc8aba1a313cd38845fda0 617 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 163 2.6E-19 T 29-03-2018 THSYN_RS13085 b0432297f99eb6a6f815500a48b078b7 202 Gene3D G3DSA:1.10.10.10 85 176 1.2E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS13085 b0432297f99eb6a6f815500a48b078b7 202 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 169 2.4E-52 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 THSYN_RS13085 b0432297f99eb6a6f815500a48b078b7 202 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 6 173 3.4E-38 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 THSYN_RS13085 b0432297f99eb6a6f815500a48b078b7 202 PIRSF PIRSF019345 1 194 4.2E-65 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 THSYN_RS13085 b0432297f99eb6a6f815500a48b078b7 202 SUPERFAMILY SSF46785 2 82 4.35E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS13085 b0432297f99eb6a6f815500a48b078b7 202 SUPERFAMILY SSF46785 84 160 3.71E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS13085 b0432297f99eb6a6f815500a48b078b7 202 Gene3D G3DSA:1.10.10.10 1 84 2.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS05645 220c31639b1cb3d8aa0ba663eea49f66 262 Gene3D G3DSA:3.40.50.10090 126 252 4.6E-20 T 29-03-2018 THSYN_RS05645 220c31639b1cb3d8aa0ba663eea49f66 262 Gene3D G3DSA:3.40.50.10090 4 125 3.5E-24 T 29-03-2018 THSYN_RS05645 220c31639b1cb3d8aa0ba663eea49f66 262 Pfam PF02602 Uroporphyrinogen-III synthase HemD 25 245 1.2E-42 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS05645 220c31639b1cb3d8aa0ba663eea49f66 262 SUPERFAMILY SSF69618 11 249 2.62E-49 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THSYN_RS03850 7c649785cb62a5e54033708eef7365ca 256 SUPERFAMILY SSF53474 1 252 2.32E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS03850 7c649785cb62a5e54033708eef7365ca 256 Gene3D G3DSA:3.40.50.1820 2 256 7.6E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS03850 7c649785cb62a5e54033708eef7365ca 256 Pfam PF12697 Alpha/beta hydrolase family 26 240 1.8E-14 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS22700 6427bf882a4fa5586159fa76165829b5 417 SUPERFAMILY SSF55124 6 161 5.52E-61 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS22700 6427bf882a4fa5586159fa76165829b5 417 Gene3D G3DSA:3.30.70.20 264 288 1.5E-4 T 29-03-2018 THSYN_RS22700 6427bf882a4fa5586159fa76165829b5 417 Gene3D G3DSA:3.30.413.10 161 263 3.2E-21 T 29-03-2018 THSYN_RS22700 6427bf882a4fa5586159fa76165829b5 417 TIGRFAM TIGR02064 dsrA: sulfite reductase, dissimilatory-type alpha subunit 11 412 2.1E-195 T 29-03-2018 IPR011806 Sulphite reductase, dissimilatory-type alpha subunit GO:0018551|GO:0020037|GO:0051539|GO:0055114 THSYN_RS22700 6427bf882a4fa5586159fa76165829b5 417 Gene3D G3DSA:3.30.413.10 289 414 2.1E-23 T 29-03-2018 THSYN_RS22700 6427bf882a4fa5586159fa76165829b5 417 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 161 379 1.8E-35 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS22700 6427bf882a4fa5586159fa76165829b5 417 SUPERFAMILY SSF56014 304 403 1.34E-49 T 29-03-2018 THSYN_RS22700 6427bf882a4fa5586159fa76165829b5 417 SUPERFAMILY SSF56014 161 235 1.34E-49 T 29-03-2018 THSYN_RS22700 6427bf882a4fa5586159fa76165829b5 417 SUPERFAMILY SSF54862 222 302 6.01E-16 T 29-03-2018 THSYN_RS22700 6427bf882a4fa5586159fa76165829b5 417 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 89 153 2.1E-9 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THSYN_RS12275 e38cbff9f5c779aa08c9afa6265ba066 245 SUPERFAMILY SSF46894 154 221 1.73E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS12275 e38cbff9f5c779aa08c9afa6265ba066 245 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 219 7.0E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS12275 e38cbff9f5c779aa08c9afa6265ba066 245 SMART SM00421 164 221 4.5E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS12275 e38cbff9f5c779aa08c9afa6265ba066 245 Pfam PF00072 Response regulator receiver domain 27 140 2.5E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS12275 e38cbff9f5c779aa08c9afa6265ba066 245 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 4.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS12275 e38cbff9f5c779aa08c9afa6265ba066 245 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 4.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS12275 e38cbff9f5c779aa08c9afa6265ba066 245 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 4.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS12275 e38cbff9f5c779aa08c9afa6265ba066 245 Gene3D G3DSA:3.40.50.2300 23 167 3.7E-28 T 29-03-2018 THSYN_RS12275 e38cbff9f5c779aa08c9afa6265ba066 245 Gene3D G3DSA:1.10.10.10 168 224 6.8E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS12275 e38cbff9f5c779aa08c9afa6265ba066 245 SUPERFAMILY SSF52172 27 175 4.27E-30 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS12275 e38cbff9f5c779aa08c9afa6265ba066 245 SMART SM00448 25 140 6.9E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS25065 a3ffba7944aadb0611f5a8d88cdfae30 613 SUPERFAMILY SSF56235 1 218 2.49E-62 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS25065 a3ffba7944aadb0611f5a8d88cdfae30 613 PIRSF PIRSF001589 1 590 1.7E-129 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS25065 a3ffba7944aadb0611f5a8d88cdfae30 613 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 570 1.3E-111 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS25065 a3ffba7944aadb0611f5a8d88cdfae30 613 Pfam PF00733 Asparagine synthase 251 586 4.0E-54 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THSYN_RS25065 a3ffba7944aadb0611f5a8d88cdfae30 613 Gene3D G3DSA:3.60.20.10 1 226 2.9E-54 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS25065 a3ffba7944aadb0611f5a8d88cdfae30 613 Pfam PF13537 Glutamine amidotransferase domain 51 170 7.5E-44 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain THSYN_RS25065 a3ffba7944aadb0611f5a8d88cdfae30 613 SUPERFAMILY SSF52402 245 393 3.85E-42 T 29-03-2018 THSYN_RS25065 a3ffba7944aadb0611f5a8d88cdfae30 613 SUPERFAMILY SSF52402 490 580 3.85E-42 T 29-03-2018 THSYN_RS25065 a3ffba7944aadb0611f5a8d88cdfae30 613 Gene3D G3DSA:3.40.50.620 232 594 7.5E-43 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS02500 c5b50b5f2d2d13176868223443b24625 205 Gene3D G3DSA:3.30.70.60 90 201 0.0014 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 THSYN_RS02500 c5b50b5f2d2d13176868223443b24625 205 Pfam PF10741 Type II secretion system (T2SS), protein M subtype b 79 199 6.8E-24 T 29-03-2018 IPR034756 Type II secretion system (T2SS), protein M subtype b THSYN_RS31155 99499f73e3b05e37c5a982028500d472 153 Pfam PF00583 Acetyltransferase (GNAT) family 50 116 2.5E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS31155 99499f73e3b05e37c5a982028500d472 153 SUPERFAMILY SSF55729 18 139 8.41E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS31155 99499f73e3b05e37c5a982028500d472 153 Gene3D G3DSA:3.40.630.30 13 153 6.1E-16 T 29-03-2018 THSYN_RS26185 98f4cb2a6d08b8980838036a82514dab 533 Pfam PF00977 Histidine biosynthesis protein 224 515 6.3E-49 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 THSYN_RS26185 98f4cb2a6d08b8980838036a82514dab 533 PIRSF PIRSF036936 1 533 2.0E-242 T 29-03-2018 IPR014640 Imidazole glycerol phosphate synthase HisHF GO:0000105|GO:0000107|GO:0016763|GO:0016833 THSYN_RS26185 98f4cb2a6d08b8980838036a82514dab 533 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 221 532 2.6E-94 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 THSYN_RS26185 98f4cb2a6d08b8980838036a82514dab 533 SUPERFAMILY SSF51366 221 531 4.24E-65 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THSYN_RS26185 98f4cb2a6d08b8980838036a82514dab 533 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 199 1.1E-59 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 THSYN_RS26185 98f4cb2a6d08b8980838036a82514dab 533 SUPERFAMILY SSF52317 2 199 4.73E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS26185 98f4cb2a6d08b8980838036a82514dab 533 Pfam PF00117 Glutamine amidotransferase class-I 4 197 2.9E-16 T 29-03-2018 IPR017926 Glutamine amidotransferase THSYN_RS26185 98f4cb2a6d08b8980838036a82514dab 533 Gene3D G3DSA:3.20.20.70 223 533 6.9E-67 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS26185 98f4cb2a6d08b8980838036a82514dab 533 Gene3D G3DSA:3.40.50.880 1 210 3.9E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS26185 98f4cb2a6d08b8980838036a82514dab 533 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 201 34.851 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 THSYN_RS02600 bf3ef315b8ec47b1cc87e79cfe99ad97 430 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 214 330 7.2E-15 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS02600 bf3ef315b8ec47b1cc87e79cfe99ad97 430 Gene3D G3DSA:3.40.50.300 167 353 6.9E-13 T 29-03-2018 THSYN_RS02600 bf3ef315b8ec47b1cc87e79cfe99ad97 430 Pfam PF13476 AAA domain 5 56 3.7E-8 T 29-03-2018 THSYN_RS02600 bf3ef315b8ec47b1cc87e79cfe99ad97 430 Gene3D G3DSA:3.40.50.300 1 84 1.9E-13 T 29-03-2018 THSYN_RS02600 bf3ef315b8ec47b1cc87e79cfe99ad97 430 SUPERFAMILY SSF52540 1 89 2.58E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02600 bf3ef315b8ec47b1cc87e79cfe99ad97 430 SUPERFAMILY SSF52540 235 334 2.58E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08240 e88a4d70eeeb7fecda3e3593cf9019cf 362 Gene3D G3DSA:3.40.109.10 2 47 7.9E-9 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THSYN_RS08240 e88a4d70eeeb7fecda3e3593cf9019cf 362 Pfam PF00881 Nitroreductase family 4 30 4.6E-6 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 THSYN_RS08240 e88a4d70eeeb7fecda3e3593cf9019cf 362 Gene3D G3DSA:3.40.109.10 93 356 1.2E-17 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THSYN_RS08240 e88a4d70eeeb7fecda3e3593cf9019cf 362 SUPERFAMILY SSF55469 4 30 1.83E-8 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THSYN_RS29675 8c1e8849c64a3684826ccc534d243ef7 95 SUPERFAMILY SSF47598 4 47 4.34E-10 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS29675 8c1e8849c64a3684826ccc534d243ef7 95 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 43 4.8E-7 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 THSYN_RS29675 8c1e8849c64a3684826ccc534d243ef7 95 Gene3D G3DSA:1.10.1220.10 5 47 4.0E-12 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS31325 d6ba7de2b21de4ff48464a2afa9ebe1e 495 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 6 493 4.1E-79 T 29-03-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 THSYN_RS31325 d6ba7de2b21de4ff48464a2afa9ebe1e 495 Gene3D G3DSA:3.50.50.60 2 492 3.1E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31325 d6ba7de2b21de4ff48464a2afa9ebe1e 495 Pfam PF01593 Flavin containing amine oxidoreductase 13 489 4.2E-24 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THSYN_RS31325 d6ba7de2b21de4ff48464a2afa9ebe1e 495 SUPERFAMILY SSF51905 1 319 8.29E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31325 d6ba7de2b21de4ff48464a2afa9ebe1e 495 SUPERFAMILY SSF51905 445 492 8.29E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS17250 db53a40fb0feba10e5a9e067f205c38a 186 Pfam PF01797 Transposase IS200 like 13 85 4.6E-5 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS17250 db53a40fb0feba10e5a9e067f205c38a 186 SMART SM01321 9 137 1.1E-20 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS17250 db53a40fb0feba10e5a9e067f205c38a 186 SUPERFAMILY SSF143422 1 143 1.7E-26 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS17250 db53a40fb0feba10e5a9e067f205c38a 186 Gene3D G3DSA:3.30.70.1290 1 144 5.0E-27 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS18720 3500dbfa21e79330342532a371029b54 655 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 195 219 2.4E-6 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat THSYN_RS19840 14a52adffc73d2a586ba0fa1fbced5d2 987 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 640 867 2.2E-6 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase THSYN_RS19840 14a52adffc73d2a586ba0fa1fbced5d2 987 Pfam PF13205 Bacterial Ig-like domain 215 314 8.3E-11 T 29-03-2018 IPR032812 SbsA, Ig-like domain THSYN_RS19840 14a52adffc73d2a586ba0fa1fbced5d2 987 Gene3D G3DSA:3.60.10.10 592 920 7.5E-29 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase THSYN_RS19840 14a52adffc73d2a586ba0fa1fbced5d2 987 SUPERFAMILY SSF56219 589 599 2.73E-27 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase THSYN_RS19840 14a52adffc73d2a586ba0fa1fbced5d2 987 SUPERFAMILY SSF56219 895 924 2.73E-27 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase THSYN_RS19840 14a52adffc73d2a586ba0fa1fbced5d2 987 SUPERFAMILY SSF56219 632 863 2.73E-27 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase THSYN_RS19840 14a52adffc73d2a586ba0fa1fbced5d2 987 ProSitePatterns PS00018 EF-hand calcium-binding domain. 961 973 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS17195 977fa292777d5a240c732e953ec6baa2 501 SUPERFAMILY SSF141523 107 245 1.31E-23 T 29-03-2018 THSYN_RS17195 977fa292777d5a240c732e953ec6baa2 501 Pfam PF03734 L,D-transpeptidase catalytic domain 108 245 3.3E-16 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 THSYN_RS17195 977fa292777d5a240c732e953ec6baa2 501 Gene3D G3DSA:2.40.440.10 103 246 4.2E-22 T 29-03-2018 THSYN_RS14800 c1fae9a8b976022fb2dcff6b95c043ff 148 SUPERFAMILY SSF46894 49 146 5.67E-11 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS14800 c1fae9a8b976022fb2dcff6b95c043ff 148 SMART SM00862 70 146 1.1E-4 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS14800 c1fae9a8b976022fb2dcff6b95c043ff 148 Pfam PF00486 Transcriptional regulatory protein, C terminal 70 146 3.6E-8 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS14800 c1fae9a8b976022fb2dcff6b95c043ff 148 Gene3D G3DSA:1.10.10.10 47 148 3.6E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS14800 c1fae9a8b976022fb2dcff6b95c043ff 148 SUPERFAMILY SSF52172 1 72 8.4E-11 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS14800 c1fae9a8b976022fb2dcff6b95c043ff 148 Gene3D G3DSA:3.40.50.2300 1 46 3.7E-7 T 29-03-2018 THSYN_RS24860 3e52538282e4495985bce92dcef52590 226 Pfam PF02481 DNA recombination-mediator protein A 56 199 6.6E-10 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 THSYN_RS24860 3e52538282e4495985bce92dcef52590 226 Gene3D G3DSA:3.40.50.450 81 191 9.3E-4 T 29-03-2018 THSYN_RS19805 307883b243951eafba72676377d94bbc 213 Pfam PF00293 NUDIX domain 49 127 2.0E-9 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THSYN_RS19805 307883b243951eafba72676377d94bbc 213 Gene3D G3DSA:3.90.79.10 18 212 2.4E-31 T 29-03-2018 THSYN_RS19805 307883b243951eafba72676377d94bbc 213 SUPERFAMILY SSF55811 49 203 8.26E-23 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 THSYN_RS30230 6aa7a512aac94352e3334aa4bc5e3ca4 470 Pfam PF14319 Transposase zinc-binding domain 42 134 8.4E-21 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS30230 6aa7a512aac94352e3334aa4bc5e3ca4 470 Pfam PF04986 Putative transposase 166 339 6.5E-42 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS18870 6df7f62e4a087b9d8ea5d202711a0e28 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 THSYN_RS18870 6df7f62e4a087b9d8ea5d202711a0e28 394 Gene3D G3DSA:3.90.1150.10 277 394 1.3E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS18870 6df7f62e4a087b9d8ea5d202711a0e28 394 Pfam PF00155 Aminotransferase class I and II 32 389 5.0E-69 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THSYN_RS18870 6df7f62e4a087b9d8ea5d202711a0e28 394 Gene3D G3DSA:3.90.1150.10 1 102 1.6E-7 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS18870 6df7f62e4a087b9d8ea5d202711a0e28 394 Gene3D G3DSA:3.40.640.10 103 276 9.4E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS18870 6df7f62e4a087b9d8ea5d202711a0e28 394 SUPERFAMILY SSF53383 4 393 2.48E-109 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS25725 2630ad3a9f791f2876be716013039d06 138 Pfam PF07728 AAA domain (dynein-related subfamily) 46 91 1.2E-4 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THSYN_RS25725 2630ad3a9f791f2876be716013039d06 138 Gene3D G3DSA:3.40.50.300 29 124 9.9E-8 T 29-03-2018 THSYN_RS25725 2630ad3a9f791f2876be716013039d06 138 SUPERFAMILY SSF52540 35 81 4.06E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08485 7d8ef0f42a7e1232a6311dd37452e644 30 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 7 27 1.6E-8 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 THSYN_RS08485 7d8ef0f42a7e1232a6311dd37452e644 30 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 7 29 1.8E-10 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 SUPERFAMILY SSF55785 419 510 6.12E-12 T 29-03-2018 IPR000014 PAS domain THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 SUPERFAMILY SSF55785 129 258 1.05E-21 T 29-03-2018 IPR000014 PAS domain THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 SUPERFAMILY SSF55785 14 132 2.84E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 140 262 3.1E-17 T 29-03-2018 IPR000014 PAS domain THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 14 138 1.1E-14 T 29-03-2018 IPR000014 PAS domain THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 Gene3D G3DSA:3.30.450.40 262 422 8.1E-21 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 Pfam PF13426 PAS domain 161 259 5.2E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 Pfam PF13426 PAS domain 28 131 9.2E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 Pfam PF13188 PAS domain 434 481 2.4E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 SMART SM00086 91 132 7.0 T 29-03-2018 IPR001610 PAC motif THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 SMART SM00086 218 260 3.3 T 29-03-2018 IPR001610 PAC motif THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 SUPERFAMILY SSF55781 288 431 1.88E-18 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 Gene3D G3DSA:3.30.450.20 135 261 7.7E-28 T 29-03-2018 THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 Gene3D G3DSA:3.30.450.20 7 134 3.0E-19 T 29-03-2018 THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 SMART SM00091 144 214 6.4E-4 T 29-03-2018 IPR000014 PAS domain THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 SMART SM00091 432 504 7.1E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 SMART SM00091 11 78 0.9 T 29-03-2018 IPR000014 PAS domain THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 SMART SM00065 282 428 4.1E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 Pfam PF01590 GAF domain 294 418 1.6E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS17555 82e1bbdb70e030b8752db50432219c2d 545 Gene3D G3DSA:3.30.450.20 423 537 2.7E-13 T 29-03-2018 THSYN_RS32865 c7e27ecd9f34a0e7624b467319785be2 255 Gene3D G3DSA:3.40.630.30 7 182 6.6E-21 T 29-03-2018 THSYN_RS32865 c7e27ecd9f34a0e7624b467319785be2 255 SUPERFAMILY SSF55729 15 160 4.46E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS32865 c7e27ecd9f34a0e7624b467319785be2 255 Pfam PF00583 Acetyltransferase (GNAT) family 78 152 3.8E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS20385 06d7556c1770ac45eb6e82ea4d5c830b 278 Pfam PF00793 DAHP synthetase I family 8 264 2.5E-67 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THSYN_RS20385 06d7556c1770ac45eb6e82ea4d5c830b 278 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 13 268 1.6E-121 T 29-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THSYN_RS20385 06d7556c1770ac45eb6e82ea4d5c830b 278 Gene3D G3DSA:3.20.20.70 11 272 2.2E-75 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS20385 06d7556c1770ac45eb6e82ea4d5c830b 278 SUPERFAMILY SSF51569 3 270 2.56E-106 T 29-03-2018 THSYN_RS20385 06d7556c1770ac45eb6e82ea4d5c830b 278 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 8 270 52.46 T 29-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THSYN_RS09180 2b361803a6dfabdb40dcb7663c52aaea 187 Pfam PF04143 Sulphur transport 27 173 2.4E-17 T 29-03-2018 IPR007272 Sulphur transport domain THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 TIGRFAM TIGR02333 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent 2 859 0.0 T 29-03-2018 IPR012708 2-methylisocitrate dehydratase AcnD, Fe/S-dependent GO:0019679 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 Gene3D G3DSA:3.20.19.10 619 859 2.2E-66 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 Gene3D G3DSA:3.30.499.10 359 547 7.8E-54 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 Gene3D G3DSA:3.30.499.10 2 227 1.7E-58 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 Pfam PF00330 Aconitase family (aconitate hydratase) 70 533 2.2E-144 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 Gene3D G3DSA:3.40.1060.10 228 358 2.1E-39 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 SUPERFAMILY SSF53732 14 587 3.27E-184 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 Pfam PF00694 Aconitase C-terminal domain 657 787 1.9E-28 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 PRINTS PR00415 Aconitase family signature 360 374 2.3E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 PRINTS PR00415 Aconitase family signature 402 413 2.3E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 PRINTS PR00415 Aconitase family signature 281 294 2.3E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 PRINTS PR00415 Aconitase family signature 162 170 2.3E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 PRINTS PR00415 Aconitase family signature 191 204 2.3E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 PRINTS PR00415 Aconitase family signature 267 280 2.3E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 PRINTS PR00415 Aconitase family signature 138 151 2.3E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 PRINTS PR00415 Aconitase family signature 205 220 2.3E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 PRINTS PR00415 Aconitase family signature 464 477 2.3E-27 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 THSYN_RS26765 6be37883268ec6d0229fc28420c2831e 864 SUPERFAMILY SSF52016 598 857 1.65E-65 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THSYN_RS31825 c93b8833b9a6730200400d4c17782f36 432 SUPERFAMILY SSF53706 14 318 2.46E-6 T 29-03-2018 THSYN_RS31825 c93b8833b9a6730200400d4c17782f36 432 Gene3D G3DSA:3.40.50.1220 61 236 8.1E-9 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS19340 1098c12d075013154343d180efb00f46 71 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 3 46 1.1E-10 T 29-03-2018 IPR022453 Zinc finger, MqsA-type THSYN_RS02295 2eac81a9db256607919083cd212b530e 417 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 3 397 42.404 T 29-03-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 THSYN_RS02295 2eac81a9db256607919083cd212b530e 417 Pfam PF00365 Phosphofructokinase 10 288 8.8E-42 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THSYN_RS02295 2eac81a9db256607919083cd212b530e 417 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 137 154 1.8E-8 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THSYN_RS02295 2eac81a9db256607919083cd212b530e 417 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 256 278 1.8E-8 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THSYN_RS02295 2eac81a9db256607919083cd212b530e 417 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 179 195 1.8E-8 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THSYN_RS02295 2eac81a9db256607919083cd212b530e 417 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 8 27 1.8E-8 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THSYN_RS02295 2eac81a9db256607919083cd212b530e 417 SUPERFAMILY SSF53784 4 410 3.92E-103 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THSYN_RS02295 2eac81a9db256607919083cd212b530e 417 Gene3D G3DSA:3.40.50.450 1 253 2.2E-45 T 29-03-2018 THSYN_RS02295 2eac81a9db256607919083cd212b530e 417 PIRSF PIRSF036483 2 416 2.5E-193 T 29-03-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 THSYN_RS25800 8519c5c1098638fe03c10627ff8b057c 194 Gene3D G3DSA:2.60.120.10 26 172 5.4E-28 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS25800 8519c5c1098638fe03c10627ff8b057c 194 SUPERFAMILY SSF51206 33 166 1.22E-29 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like THSYN_RS25800 8519c5c1098638fe03c10627ff8b057c 194 Pfam PF00027 Cyclic nucleotide-binding domain 59 142 7.2E-20 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS25800 8519c5c1098638fe03c10627ff8b057c 194 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 106 123 - T 29-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site THSYN_RS25800 8519c5c1098638fe03c10627ff8b057c 194 SMART SM00100 39 156 1.2E-19 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS25800 8519c5c1098638fe03c10627ff8b057c 194 PRINTS PR00103 cAMP-dependent protein kinase signature 75 89 3.4E-6 T 29-03-2018 THSYN_RS25800 8519c5c1098638fe03c10627ff8b057c 194 PRINTS PR00103 cAMP-dependent protein kinase signature 116 127 3.4E-6 T 29-03-2018 THSYN_RS25800 8519c5c1098638fe03c10627ff8b057c 194 PRINTS PR00103 cAMP-dependent protein kinase signature 104 113 3.4E-6 T 29-03-2018 THSYN_RS25800 8519c5c1098638fe03c10627ff8b057c 194 PRINTS PR00103 cAMP-dependent protein kinase signature 60 74 3.4E-6 T 29-03-2018 THSYN_RS08945 81ebb9eba1d81af52b7d474f5e0d3dbb 234 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 111 197 3.0E-15 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THSYN_RS08945 81ebb9eba1d81af52b7d474f5e0d3dbb 234 Gene3D G3DSA:3.30.420.130 95 216 8.6E-29 T 29-03-2018 THSYN_RS08945 81ebb9eba1d81af52b7d474f5e0d3dbb 234 Pfam PF16844 Dinitrogenase iron-molybdenum cofactor, N-terminal 5 87 1.4E-23 T 29-03-2018 IPR031763 Dinitrogenase iron-molybdenum cofactor, N-terminal THSYN_RS08945 81ebb9eba1d81af52b7d474f5e0d3dbb 234 SUPERFAMILY SSF53146 98 215 2.22E-29 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THSYN_RS19855 aa7f146ade97e429c3a0ac5bf82ed8da 601 SUPERFAMILY SSF55073 427 595 3.77E-21 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS19855 aa7f146ade97e429c3a0ac5bf82ed8da 601 SUPERFAMILY SSF54631 295 413 2.5E-10 T 29-03-2018 THSYN_RS19855 aa7f146ade97e429c3a0ac5bf82ed8da 601 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 438 513 1.1E-12 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS19855 aa7f146ade97e429c3a0ac5bf82ed8da 601 Pfam PF00563 EAL domain 23 255 7.0E-6 T 29-03-2018 IPR001633 EAL domain THSYN_RS19855 aa7f146ade97e429c3a0ac5bf82ed8da 601 Pfam PF00571 CBS domain 295 340 4.5E-4 T 29-03-2018 IPR000644 CBS domain THSYN_RS19855 aa7f146ade97e429c3a0ac5bf82ed8da 601 SUPERFAMILY SSF141868 24 259 6.28E-5 T 29-03-2018 IPR001633 EAL domain THSYN_RS19855 aa7f146ade97e429c3a0ac5bf82ed8da 601 Gene3D G3DSA:3.20.20.450 20 272 6.5E-9 T 29-03-2018 IPR001633 EAL domain THSYN_RS19855 aa7f146ade97e429c3a0ac5bf82ed8da 601 Gene3D G3DSA:3.10.580.10 290 419 1.4E-12 T 29-03-2018 THSYN_RS19855 aa7f146ade97e429c3a0ac5bf82ed8da 601 Pfam PF00990 Diguanylate cyclase, GGDEF domain 428 513 8.1E-13 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS19855 aa7f146ade97e429c3a0ac5bf82ed8da 601 Gene3D G3DSA:3.30.70.270 420 598 1.5E-23 T 29-03-2018 THSYN_RS19855 aa7f146ade97e429c3a0ac5bf82ed8da 601 SMART SM00267 410 597 4.2E-7 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS21520 01af478e73366bac0d73e0132f291fe4 277 SUPERFAMILY SSF53335 39 235 3.02E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS21520 01af478e73366bac0d73e0132f291fe4 277 Gene3D G3DSA:3.40.50.150 3 241 1.5E-18 T 29-03-2018 THSYN_RS21520 01af478e73366bac0d73e0132f291fe4 277 Pfam PF08003 Protein of unknown function (DUF1698) 49 158 4.8E-7 T 29-03-2018 IPR027555 tRNA (mo5U34)-methyltransferase-like THSYN_RS11090 ecd9643da9223b8eb2db7ec0a8be9163 137 Pfam PF01844 HNH endonuclease 51 99 1.0E-10 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 THSYN_RS11090 ecd9643da9223b8eb2db7ec0a8be9163 137 Gene3D G3DSA:3.40.1800.10 29 110 1.1E-5 T 29-03-2018 THSYN_RS11090 ecd9643da9223b8eb2db7ec0a8be9163 137 SMART SM00507 39 94 6.1E-4 T 29-03-2018 IPR003615 HNH nuclease THSYN_RS19115 ee3808fb01a8d07c495832781c5ef4ff 265 Gene3D G3DSA:3.90.1580.10 94 265 2.8E-51 T 29-03-2018 THSYN_RS19115 ee3808fb01a8d07c495832781c5ef4ff 265 Gene3D G3DSA:3.90.1580.10 31 93 6.8E-7 T 29-03-2018 THSYN_RS19115 ee3808fb01a8d07c495832781c5ef4ff 265 Pfam PF03781 Sulfatase-modifying factor enzyme 1 40 263 3.8E-45 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS19115 ee3808fb01a8d07c495832781c5ef4ff 265 SUPERFAMILY SSF56436 38 263 3.53E-60 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS24715 7b38a4d7c6825d599784911a99eb31d3 257 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 176 242 4.8E-14 T 29-03-2018 IPR006440 Death on curing protein GO:0016301 THSYN_RS24715 7b38a4d7c6825d599784911a99eb31d3 257 Gene3D G3DSA:1.10.3290.10 102 249 6.1E-9 T 29-03-2018 IPR003812 Fido domain THSYN_RS24715 7b38a4d7c6825d599784911a99eb31d3 257 SUPERFAMILY SSF140931 149 213 4.45E-8 T 29-03-2018 IPR003812 Fido domain THSYN_RS24715 7b38a4d7c6825d599784911a99eb31d3 257 Pfam PF02661 Fic/DOC family 125 206 6.9E-12 T 29-03-2018 IPR003812 Fido domain THSYN_RS02355 8bd6ab04eb267712fa916e9f49417a56 82 Pfam PF14375 Cysteine-rich CWC 13 58 2.6E-10 T 29-03-2018 IPR032720 Cysteine-rich CWC THSYN_RS15280 5a7762e61f3b62581c228f8786254b50 451 SUPERFAMILY SSF111369 84 339 9.15E-17 T 29-03-2018 THSYN_RS15280 5a7762e61f3b62581c228f8786254b50 451 Gene3D G3DSA:1.20.1600.10 56 401 9.0E-31 T 29-03-2018 THSYN_RS15280 5a7762e61f3b62581c228f8786254b50 451 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 87 335 1.1E-17 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS15280 5a7762e61f3b62581c228f8786254b50 451 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 75 358 1.8E-43 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS09570 0bdff887402c6340db11074e7e581514 149 SMART SM00226 2 143 2.9E-42 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS09570 0bdff887402c6340db11074e7e581514 149 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 1 141 6.8E-38 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS09570 0bdff887402c6340db11074e7e581514 149 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 96 109 3.8E-14 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS09570 0bdff887402c6340db11074e7e581514 149 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 73 88 3.8E-14 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS09570 0bdff887402c6340db11074e7e581514 149 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 39 55 3.8E-14 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS09570 0bdff887402c6340db11074e7e581514 149 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 115 130 3.8E-14 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THSYN_RS09570 0bdff887402c6340db11074e7e581514 149 SUPERFAMILY SSF52788 1 144 6.02E-48 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily THSYN_RS09570 0bdff887402c6340db11074e7e581514 149 Gene3D G3DSA:3.40.50.2300 1 148 2.4E-48 T 29-03-2018 THSYN_RS03205 a0831580064969c3a0c12782a5fdac57 203 Gene3D G3DSA:1.10.10.440 69 126 0.0013 T 29-03-2018 THSYN_RS27965 f56102b97176d571ad5714e943895fe3 487 Gene3D G3DSA:1.20.1250.20 293 486 7.6E-13 T 29-03-2018 THSYN_RS27965 f56102b97176d571ad5714e943895fe3 487 Gene3D G3DSA:1.20.1250.20 19 227 4.5E-10 T 29-03-2018 THSYN_RS27965 f56102b97176d571ad5714e943895fe3 487 Pfam PF13000 Acetyl-coenzyme A transporter 1 27 144 1.1E-6 T 29-03-2018 IPR024371 Acetyl-coenzyme A transporter 1 GO:0008521|GO:0016021 Reactome: R-HSA-425397 THSYN_RS27965 f56102b97176d571ad5714e943895fe3 487 SUPERFAMILY SSF103473 22 231 7.46E-18 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS27965 f56102b97176d571ad5714e943895fe3 487 SUPERFAMILY SSF103473 279 484 7.46E-18 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS05850 97865a9f8cb5876120b5b2dc3c46bca2 263 Gene3D G3DSA:3.90.1570.10 6 174 4.8E-10 T 29-03-2018 THSYN_RS05850 97865a9f8cb5876120b5b2dc3c46bca2 263 Pfam PF05685 Putative restriction endonuclease 19 157 3.9E-8 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS05850 97865a9f8cb5876120b5b2dc3c46bca2 263 SUPERFAMILY SSF52980 17 171 3.54E-13 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS03550 091bba5ed60d349086ba95e3913df452 403 Pfam PF01098 Cell cycle protein 31 384 6.0E-100 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 THSYN_RS03550 091bba5ed60d349086ba95e3913df452 403 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 30 383 2.0E-125 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 THSYN_RS03550 091bba5ed60d349086ba95e3913df452 403 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 25 393 39.181 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 THSYN_RS27015 9ddf2577f343879e53f9467b79886777 80 SUPERFAMILY SSF143120 1 46 3.79E-10 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS27015 9ddf2577f343879e53f9467b79886777 80 Gene3D G3DSA:3.40.1620.10 1 39 5.2E-13 T 29-03-2018 THSYN_RS27015 9ddf2577f343879e53f9467b79886777 80 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 42 1.5E-7 T 29-03-2018 THSYN_RS27015 9ddf2577f343879e53f9467b79886777 80 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 49 7.2E-10 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS00300 00211ab33547256fa84de41f7a7c8940 393 SUPERFAMILY SSF53850 23 390 8.89E-84 T 29-03-2018 THSYN_RS00300 00211ab33547256fa84de41f7a7c8940 393 Gene3D G3DSA:3.40.190.10 27 149 6.4E-5 T 29-03-2018 THSYN_RS00300 00211ab33547256fa84de41f7a7c8940 393 Pfam PF13416 Bacterial extracellular solute-binding protein 43 330 4.1E-42 T 29-03-2018 THSYN_RS00300 00211ab33547256fa84de41f7a7c8940 393 PRINTS PR00181 Maltose binding protein signature 31 49 2.4E-51 T 29-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 THSYN_RS00300 00211ab33547256fa84de41f7a7c8940 393 PRINTS PR00181 Maltose binding protein signature 354 373 2.4E-51 T 29-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 THSYN_RS00300 00211ab33547256fa84de41f7a7c8940 393 PRINTS PR00181 Maltose binding protein signature 125 144 2.4E-51 T 29-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 THSYN_RS00300 00211ab33547256fa84de41f7a7c8940 393 PRINTS PR00181 Maltose binding protein signature 296 317 2.4E-51 T 29-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 THSYN_RS00300 00211ab33547256fa84de41f7a7c8940 393 PRINTS PR00181 Maltose binding protein signature 230 249 2.4E-51 T 29-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 THSYN_RS00300 00211ab33547256fa84de41f7a7c8940 393 PRINTS PR00181 Maltose binding protein signature 167 186 2.4E-51 T 29-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 THSYN_RS00300 00211ab33547256fa84de41f7a7c8940 393 PRINTS PR00181 Maltose binding protein signature 65 83 2.4E-51 T 29-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 THSYN_RS00300 00211ab33547256fa84de41f7a7c8940 393 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 128 145 - T 29-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 THSYN_RS00300 00211ab33547256fa84de41f7a7c8940 393 Gene3D G3DSA:3.40.190.10 150 393 4.4E-34 T 29-03-2018 THSYN_RS02570 ab47d19dd283ddec65f39793ad237f1a 226 SUPERFAMILY SSF53335 21 211 1.72E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02570 ab47d19dd283ddec65f39793ad237f1a 226 Gene3D G3DSA:3.40.50.150 2 217 1.3E-24 T 29-03-2018 THSYN_RS02570 ab47d19dd283ddec65f39793ad237f1a 226 Pfam PF13489 Methyltransferase domain 40 204 1.5E-12 T 29-03-2018 THSYN_RS22845 992055de00252251d749d7052361417f 185 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 40 181 2.3E-39 T 29-03-2018 IPR005247 YbhB/YbcL THSYN_RS22845 992055de00252251d749d7052361417f 185 Pfam PF01161 Phosphatidylethanolamine-binding protein 44 181 2.4E-36 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein THSYN_RS22845 992055de00252251d749d7052361417f 185 Gene3D G3DSA:3.90.280.10 9 184 2.9E-49 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein THSYN_RS22845 992055de00252251d749d7052361417f 185 SUPERFAMILY SSF49777 22 183 1.83E-51 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 Gene3D G3DSA:3.90.199.10 34 286 2.1E-118 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 540 586 5.2E-9 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 794 838 1.2E-11 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 648 690 2.4E-8 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 745 775 2.6E-11 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 590 639 1.3E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 695 739 2.5E-14 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 840 0.0 T 29-03-2018 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 Gene3D G3DSA:1.10.268.10 377 499 3.2E-48 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 SMART SM00434 11 501 1.7E-286 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 508 3.4E-150 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 Gene3D G3DSA:3.90.199.10 287 376 1.3E-7 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 SUPERFAMILY SSF101904 535 848 4.05E-104 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 SUPERFAMILY SSF56719 30 523 1.44E-179 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 5 842 23.941 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THSYN_RS20835 7ee28181322022aba0f2859aca2f126c 894 Gene3D G3DSA:2.120.10.90 532 842 1.3E-124 T 29-03-2018 THSYN_RS19815 fcbe86b8c63cfa85f0213c9027ab68ec 348 SUPERFAMILY SSF103486 8 334 1.57E-27 T 29-03-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS19815 fcbe86b8c63cfa85f0213c9027ab68ec 348 Pfam PF01992 ATP synthase (C/AC39) subunit 10 334 5.5E-46 T 29-03-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS19815 fcbe86b8c63cfa85f0213c9027ab68ec 348 Gene3D G3DSA:1.20.1690.10 83 186 6.1E-12 T 29-03-2018 IPR035067 V-type ATPase subunit c domain Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS10305 a516dc558d4a78cf4a6ed50b453a2281 332 Pfam PF04055 Radical SAM superfamily 59 215 4.3E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS10305 a516dc558d4a78cf4a6ed50b453a2281 332 SMART SM00729 39 266 2.0E-43 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS10305 a516dc558d4a78cf4a6ed50b453a2281 332 SUPERFAMILY SSF102114 28 312 1.83E-47 T 29-03-2018 THSYN_RS10305 a516dc558d4a78cf4a6ed50b453a2281 332 Gene3D G3DSA:3.20.20.70 15 311 3.0E-38 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS10305 a516dc558d4a78cf4a6ed50b453a2281 332 Pfam PF16199 Radical_SAM C-terminal domain 228 310 7.8E-23 T 29-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 THSYN_RS10305 a516dc558d4a78cf4a6ed50b453a2281 332 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 22 319 2.0E-113 T 29-03-2018 IPR005911 Protein YhcC-like GO:0051536 THSYN_RS00200 c4a021b3698c9ca9fd22d340e6516585 263 Pfam PF01875 Memo-like protein 6 259 1.8E-48 T 29-03-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 THSYN_RS00200 c4a021b3698c9ca9fd22d340e6516585 263 Hamap MF_00055 MEMO1 family protein . 3 263 47.632 T 29-03-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 THSYN_RS00200 c4a021b3698c9ca9fd22d340e6516585 263 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 5 262 4.0E-77 T 29-03-2018 THSYN_RS00200 c4a021b3698c9ca9fd22d340e6516585 263 Gene3D G3DSA:3.40.830.10 21 263 7.9E-27 T 29-03-2018 THSYN_RS00200 c4a021b3698c9ca9fd22d340e6516585 263 SUPERFAMILY SSF53213 36 207 8.11E-6 T 29-03-2018 THSYN_RS26975 ef7c675a3096657a7baec87d2f80d162 92 Pfam PF03658 RnfH family Ubiquitin 1 82 1.8E-32 T 29-03-2018 IPR005346 RnfH protein THSYN_RS26975 ef7c675a3096657a7baec87d2f80d162 92 Hamap MF_00460 Protein RnfH [rnfH]. 1 92 23.381 T 29-03-2018 IPR005346 RnfH protein THSYN_RS26975 ef7c675a3096657a7baec87d2f80d162 92 Gene3D G3DSA:3.10.20.280 1 84 3.5E-31 T 29-03-2018 IPR005346 RnfH protein THSYN_RS26975 ef7c675a3096657a7baec87d2f80d162 92 SUPERFAMILY SSF54285 1 75 2.65E-25 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THSYN_RS01510 a0fa7f7231ec2d90953a4e1fe26a68f7 432 Pfam PF04348 LppC putative lipoprotein 55 375 5.0E-69 T 29-03-2018 IPR007443 Penicillin-binding protein activator LpoA THSYN_RS01510 a0fa7f7231ec2d90953a4e1fe26a68f7 432 Gene3D G3DSA:3.40.50.2300 199 368 2.1E-20 T 29-03-2018 THSYN_RS01510 a0fa7f7231ec2d90953a4e1fe26a68f7 432 Gene3D G3DSA:3.40.50.2300 38 198 0.0085 T 29-03-2018 THSYN_RS01510 a0fa7f7231ec2d90953a4e1fe26a68f7 432 SUPERFAMILY SSF53822 55 380 4.37E-64 T 29-03-2018 IPR028082 Periplasmic binding protein-like I THSYN_RS11040 78f2be0fadbaee04629f03b38c50463e 100 SUPERFAMILY SSF46785 29 79 2.92E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS11040 78f2be0fadbaee04629f03b38c50463e 100 Gene3D G3DSA:1.10.10.10 19 100 5.8E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS21190 ff68191dcab4b8aeff6c6e6b8797c39e 295 Pfam PF05050 Methyltransferase FkbM domain 98 239 6.5E-8 T 29-03-2018 IPR006342 Methyltransferase FkbM THSYN_RS21190 ff68191dcab4b8aeff6c6e6b8797c39e 295 Gene3D G3DSA:3.40.50.150 78 265 1.4E-19 T 29-03-2018 THSYN_RS21190 ff68191dcab4b8aeff6c6e6b8797c39e 295 SUPERFAMILY SSF53335 82 241 2.72E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS21190 ff68191dcab4b8aeff6c6e6b8797c39e 295 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 95 232 7.9E-19 T 29-03-2018 IPR006342 Methyltransferase FkbM THSYN_RS01235 b6d52134d3b9033aa8a47276a9193873 424 Gene3D G3DSA:3.40.50.2000 200 362 0.0029 T 29-03-2018 THSYN_RS08100 6fcac3320defc66e1a80e9902221f7ea 145 Gene3D G3DSA:1.10.10.10 54 131 0.0012 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS08100 6fcac3320defc66e1a80e9902221f7ea 145 Gene3D G3DSA:1.10.3290.10 2 53 1.8E-8 T 29-03-2018 IPR003812 Fido domain THSYN_RS08100 6fcac3320defc66e1a80e9902221f7ea 145 SUPERFAMILY SSF140931 2 60 1.57E-7 T 29-03-2018 IPR003812 Fido domain THSYN_RS14185 79f05abea798859d38cfb9dd90e7d75c 617 Gene3D G3DSA:3.30.750.24 444 581 4.7E-20 T 29-03-2018 IPR002645 STAS domain THSYN_RS14185 79f05abea798859d38cfb9dd90e7d75c 617 Pfam PF01740 STAS domain 467 568 2.9E-15 T 29-03-2018 IPR002645 STAS domain THSYN_RS14185 79f05abea798859d38cfb9dd90e7d75c 617 TIGRFAM TIGR00815 sulP: sulfate permease 29 568 5.0E-123 T 29-03-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 THSYN_RS14185 79f05abea798859d38cfb9dd90e7d75c 617 SUPERFAMILY SSF52091 464 576 2.35E-16 T 29-03-2018 IPR002645 STAS domain THSYN_RS14185 79f05abea798859d38cfb9dd90e7d75c 617 Pfam PF00916 Sulfate permease family 42 413 1.4E-90 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 THSYN_RS33115 b2b73dc89133660f97752c26b4bd29d7 314 Gene3D G3DSA:1.50.10.20 138 235 1.5E-5 T 29-03-2018 THSYN_RS33115 b2b73dc89133660f97752c26b4bd29d7 314 Gene3D G3DSA:1.50.10.20 1 137 3.3E-23 T 29-03-2018 THSYN_RS33115 b2b73dc89133660f97752c26b4bd29d7 314 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 2 110 3.5E-9 T 29-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 THSYN_RS33115 b2b73dc89133660f97752c26b4bd29d7 314 SUPERFAMILY SSF48239 2 204 1.53E-21 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid THSYN_RS21365 b38526d3f2420d23ed16c7e70c5d6d24 554 Gene3D G3DSA:3.30.1890.10 61 457 8.7E-17 T 29-03-2018 THSYN_RS21365 b38526d3f2420d23ed16c7e70c5d6d24 554 SUPERFAMILY SSF90257 189 305 8.89E-5 T 29-03-2018 THSYN_RS21365 b38526d3f2420d23ed16c7e70c5d6d24 554 TIGRFAM TIGR03007 pepcterm_ChnLen: polysaccharide chain length determinant protein, PEP-CTERM locus subfamily 37 541 5.5E-149 T 29-03-2018 IPR014345 PEP-CTERM locus polysaccharide chain length determinant THSYN_RS05425 cde50a2f9aad449d65858b5a1d98ad60 543 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 508 532 1.3E-4 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS05425 cde50a2f9aad449d65858b5a1d98ad60 543 Pfam PF07589 PEP-CTERM motif 507 532 2.1E-5 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS15025 a8a19fb7ccb2e469be694d835eaa8d42 406 SUPERFAMILY SSF48239 80 403 1.36E-33 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid THSYN_RS15025 a8a19fb7ccb2e469be694d835eaa8d42 406 Gene3D G3DSA:1.50.10.20 202 406 9.9E-20 T 29-03-2018 THSYN_RS15025 a8a19fb7ccb2e469be694d835eaa8d42 406 Gene3D G3DSA:1.50.10.20 16 201 2.1E-16 T 29-03-2018 THSYN_RS15025 a8a19fb7ccb2e469be694d835eaa8d42 406 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 135 169 1.2 T 29-03-2018 IPR001330 PFTB repeat GO:0003824 THSYN_RS15025 a8a19fb7ccb2e469be694d835eaa8d42 406 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 84 104 0.29 T 29-03-2018 IPR001330 PFTB repeat GO:0003824 THSYN_RS24600 68d3e00dbb108e8fb31fc92e85241b39 163 Gene3D G3DSA:3.30.70.20 22 74 2.1E-6 T 29-03-2018 THSYN_RS24600 68d3e00dbb108e8fb31fc92e85241b39 163 Gene3D G3DSA:3.30.70.20 75 107 1.6E-12 T 29-03-2018 THSYN_RS24600 68d3e00dbb108e8fb31fc92e85241b39 163 Pfam PF12838 4Fe-4S dicluster domain 63 116 5.4E-11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS24600 68d3e00dbb108e8fb31fc92e85241b39 163 Gene3D G3DSA:3.30.70.20 108 155 1.7E-4 T 29-03-2018 THSYN_RS24600 68d3e00dbb108e8fb31fc92e85241b39 163 SUPERFAMILY SSF54862 37 146 3.47E-23 T 29-03-2018 THSYN_RS24600 68d3e00dbb108e8fb31fc92e85241b39 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 103 114 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS24600 68d3e00dbb108e8fb31fc92e85241b39 163 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 11 160 26.759 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24600 68d3e00dbb108e8fb31fc92e85241b39 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 64 75 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS24600 68d3e00dbb108e8fb31fc92e85241b39 163 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 20 141 2.2E-42 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS22640 60a6be45bb92870add85352d67fb127c 463 Gene3D G3DSA:3.40.50.300 2 40 6.6E-8 T 29-03-2018 THSYN_RS22640 60a6be45bb92870add85352d67fb127c 463 Gene3D G3DSA:3.40.50.300 45 191 1.0E-28 T 29-03-2018 THSYN_RS22640 60a6be45bb92870add85352d67fb127c 463 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 1 447 37.579 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 THSYN_RS22640 60a6be45bb92870add85352d67fb127c 463 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 441 1.0E-34 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 THSYN_RS22640 60a6be45bb92870add85352d67fb127c 463 SUPERFAMILY SSF52540 1 196 1.83E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22640 60a6be45bb92870add85352d67fb127c 463 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 13 187 1.0E-15 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THSYN_RS22640 60a6be45bb92870add85352d67fb127c 463 Gene3D G3DSA:3.40.50.880 195 436 9.0E-21 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS22640 60a6be45bb92870add85352d67fb127c 463 SUPERFAMILY SSF52317 248 459 5.09E-31 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS22640 60a6be45bb92870add85352d67fb127c 463 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 10 444 9.0E-119 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 THSYN_RS13195 3c4a25ecddff4bbf1c2f811c423b7748 428 Gene3D G3DSA:3.40.50.300 33 217 4.3E-6 T 29-03-2018 THSYN_RS13195 3c4a25ecddff4bbf1c2f811c423b7748 428 Pfam PF13191 AAA ATPase domain 46 177 1.7E-9 T 29-03-2018 THSYN_RS13195 3c4a25ecddff4bbf1c2f811c423b7748 428 SUPERFAMILY SSF52540 39 300 5.1E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29735 b913524dfc1e4f1493b8676c71a4c71f 106 SUPERFAMILY SSF143414 9 95 3.01E-28 T 29-03-2018 THSYN_RS29735 b913524dfc1e4f1493b8676c71a4c71f 106 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 9 70 3.0E-19 T 29-03-2018 THSYN_RS29735 b913524dfc1e4f1493b8676c71a4c71f 106 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 26 45 - T 29-03-2018 IPR020808 Bacterial microcompartments protein, conserved site THSYN_RS29735 b913524dfc1e4f1493b8676c71a4c71f 106 SMART SM00877 8 85 8.5E-31 T 29-03-2018 IPR000249 Microcompartment protein, bacteria THSYN_RS29735 b913524dfc1e4f1493b8676c71a4c71f 106 Pfam PF00936 BMC domain 9 85 9.3E-26 T 29-03-2018 IPR000249 Microcompartment protein, bacteria THSYN_RS06595 16809371e4ba71397ba0a0000d9a4441 75 SUPERFAMILY SSF46689 3 70 2.87E-23 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS06595 16809371e4ba71397ba0a0000d9a4441 75 Pfam PF04255 Protein of unknown function (DUF433) 6 61 5.5E-24 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS06595 16809371e4ba71397ba0a0000d9a4441 75 Gene3D G3DSA:1.10.10.10 6 69 2.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS06615 098c94f2dc45a83702d9d7af830e6729 155 Gene3D G3DSA:3.30.70.920 56 154 3.4E-25 T 29-03-2018 THSYN_RS06615 098c94f2dc45a83702d9d7af830e6729 155 Gene3D G3DSA:1.10.10.10 4 55 3.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS06615 098c94f2dc45a83702d9d7af830e6729 155 SUPERFAMILY SSF46785 2 63 5.86E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS06615 098c94f2dc45a83702d9d7af830e6729 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 1.9E-20 T 29-03-2018 THSYN_RS06615 098c94f2dc45a83702d9d7af830e6729 155 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site THSYN_RS06615 098c94f2dc45a83702d9d7af830e6729 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.9E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 THSYN_RS06615 098c94f2dc45a83702d9d7af830e6729 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.9E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 THSYN_RS06615 098c94f2dc45a83702d9d7af830e6729 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.9E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 THSYN_RS06615 098c94f2dc45a83702d9d7af830e6729 155 SMART SM00344 3 113 5.2E-41 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 THSYN_RS06615 098c94f2dc45a83702d9d7af830e6729 155 Pfam PF01037 Lrp/AsnC ligand binding domain 70 144 1.0E-22 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THSYN_RS06615 098c94f2dc45a83702d9d7af830e6729 155 SUPERFAMILY SSF54909 63 153 5.36E-20 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel THSYN_RS11105 82c7cc24fcb0e1cef2e6c094747c2b1f 412 SUPERFAMILY SSF109604 310 381 2.83E-29 T 29-03-2018 THSYN_RS11105 82c7cc24fcb0e1cef2e6c094747c2b1f 412 SUPERFAMILY SSF109604 161 257 2.83E-29 T 29-03-2018 THSYN_RS11105 82c7cc24fcb0e1cef2e6c094747c2b1f 412 SMART SM00471 171 354 2.6E-6 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS11105 82c7cc24fcb0e1cef2e6c094747c2b1f 412 Pfam PF13487 HD domain 263 336 5.4E-13 T 29-03-2018 THSYN_RS11105 82c7cc24fcb0e1cef2e6c094747c2b1f 412 Gene3D G3DSA:1.10.3210.10 151 395 1.5E-42 T 29-03-2018 THSYN_RS11105 82c7cc24fcb0e1cef2e6c094747c2b1f 412 SUPERFAMILY SSF52172 9 142 5.12E-34 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS11105 82c7cc24fcb0e1cef2e6c094747c2b1f 412 SMART SM00448 9 122 5.5E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS11105 82c7cc24fcb0e1cef2e6c094747c2b1f 412 Pfam PF00072 Response regulator receiver domain 11 122 2.0E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS11105 82c7cc24fcb0e1cef2e6c094747c2b1f 412 Gene3D G3DSA:3.40.50.2300 6 150 3.3E-31 T 29-03-2018 THSYN_RS22045 d14f9596523d7c4e070e21c8b6773785 260 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 167 185 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 THSYN_RS22045 d14f9596523d7c4e070e21c8b6773785 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 69 82 1.4E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THSYN_RS22045 d14f9596523d7c4e070e21c8b6773785 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 91 107 1.4E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THSYN_RS22045 d14f9596523d7c4e070e21c8b6773785 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 192 204 1.4E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THSYN_RS22045 d14f9596523d7c4e070e21c8b6773785 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 161 173 1.4E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THSYN_RS22045 d14f9596523d7c4e070e21c8b6773785 260 Hamap MF_01974 Methionine aminopeptidase [map]. 3 250 42.341 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 THSYN_RS22045 d14f9596523d7c4e070e21c8b6773785 260 Gene3D G3DSA:3.90.230.10 2 257 6.2E-89 T 29-03-2018 THSYN_RS22045 d14f9596523d7c4e070e21c8b6773785 260 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 249 2.4E-97 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 THSYN_RS22045 d14f9596523d7c4e070e21c8b6773785 260 Pfam PF00557 Metallopeptidase family M24 12 241 3.4E-57 T 29-03-2018 IPR000994 Peptidase M24 THSYN_RS22045 d14f9596523d7c4e070e21c8b6773785 260 SUPERFAMILY SSF55920 4 252 2.88E-94 T 29-03-2018 IPR000994 Peptidase M24 THSYN_RS03715 38767c093731f142d10a1816be961b26 124 Gene3D G3DSA:1.20.120.330 3 122 5.3E-4 T 29-03-2018 THSYN_RS15635 e4f94cede96e5991161f79eb2401280f 323 SUPERFAMILY SSF117892 74 199 3.53E-17 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS15635 e4f94cede96e5991161f79eb2401280f 323 Pfam PF01145 SPFH domain / Band 7 family 35 203 4.6E-14 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS01205 ddb195f5558776bdc7d4b7eda4b2d8e0 148 Gene3D G3DSA:1.20.120.330 1 134 1.4E-16 T 29-03-2018 THSYN_RS01205 ddb195f5558776bdc7d4b7eda4b2d8e0 148 Pfam PF01934 Protein of unknown function DUF86 34 119 4.2E-13 T 29-03-2018 IPR008201 Protein of unknown function DUF86 THSYN_RS26260 97c8fb61da6034eaa2b837d4682f4168 156 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 155 31.449 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THSYN_RS26260 97c8fb61da6034eaa2b837d4682f4168 156 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 16 151 8.9E-55 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THSYN_RS26260 97c8fb61da6034eaa2b837d4682f4168 156 SUPERFAMILY SSF52121 5 155 5.36E-62 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THSYN_RS26260 97c8fb61da6034eaa2b837d4682f4168 156 Gene3D G3DSA:3.40.50.960 3 156 4.4E-63 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THSYN_RS26260 97c8fb61da6034eaa2b837d4682f4168 156 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 15 152 1.5E-57 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THSYN_RS09990 588d526498afa6019ed4f89ab9e9dc49 695 SUPERFAMILY SSF53300 133 193 3.25E-5 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS09990 588d526498afa6019ed4f89ab9e9dc49 695 Gene3D G3DSA:3.40.50.410 9 229 1.6E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS31095 a47f06b8aa654814192b8082e6e19654 361 SUPERFAMILY SSF53850 46 360 3.72E-81 T 29-03-2018 THSYN_RS31095 a47f06b8aa654814192b8082e6e19654 361 Gene3D G3DSA:3.40.190.10 43 179 1.1E-28 T 29-03-2018 THSYN_RS31095 a47f06b8aa654814192b8082e6e19654 361 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 46 359 4.0E-98 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 THSYN_RS31095 a47f06b8aa654814192b8082e6e19654 361 Gene3D G3DSA:3.40.190.10 180 360 2.0E-20 T 29-03-2018 THSYN_RS31095 a47f06b8aa654814192b8082e6e19654 361 PIRSF PIRSF002756 2 361 5.7E-99 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 THSYN_RS31095 a47f06b8aa654814192b8082e6e19654 361 Pfam PF12849 PBP superfamily domain 41 321 5.4E-58 T 29-03-2018 IPR024370 PBP domain THSYN_RS13395 84c12076a782dcb9fed7dc9e9abc8de7 176 Pfam PF07963 Prokaryotic N-terminal methylation motif 26 48 4.6E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS13395 84c12076a782dcb9fed7dc9e9abc8de7 176 Gene3D G3DSA:3.30.700.10 28 172 8.7E-23 T 29-03-2018 THSYN_RS13395 84c12076a782dcb9fed7dc9e9abc8de7 176 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 26 46 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS13395 84c12076a782dcb9fed7dc9e9abc8de7 176 SUPERFAMILY SSF54523 28 140 8.63E-20 T 29-03-2018 THSYN_RS13395 84c12076a782dcb9fed7dc9e9abc8de7 176 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 49 141 4.6E-15 T 29-03-2018 IPR031982 Type IV minor pilin ComP THSYN_RS13395 84c12076a782dcb9fed7dc9e9abc8de7 176 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 26 48 4.3E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS10155 a2879d0a5b50e3f804a7550ed1f20327 98 Pfam PF11006 Protein of unknown function (DUF2845) 27 94 2.9E-7 T 29-03-2018 IPR021268 Protein of unknown function DUF2845 THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Gene3D G3DSA:2.60.40.10 622 687 1.0E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Gene3D G3DSA:2.60.40.10 803 881 9.1E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Gene3D G3DSA:2.130.10.130 318 474 3.9E-8 T 29-03-2018 THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Gene3D G3DSA:2.130.10.130 63 134 0.018 T 29-03-2018 THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Gene3D G3DSA:2.130.10.130 180 317 1.8E-17 T 29-03-2018 THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF05593 RHS Repeat 1160 1182 1.2E-4 T 29-03-2018 IPR031325 RHS repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF05593 RHS Repeat 1230 1261 7.6E-5 T 29-03-2018 IPR031325 RHS repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF05593 RHS Repeat 1606 1637 2.1E-9 T 29-03-2018 IPR031325 RHS repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF05593 RHS Repeat 1097 1130 5.8E-9 T 29-03-2018 IPR031325 RHS repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF05593 RHS Repeat 1419 1454 5.4E-7 T 29-03-2018 IPR031325 RHS repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF05593 RHS Repeat 1779 1814 5.7E-6 T 29-03-2018 IPR031325 RHS repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF05593 RHS Repeat 1758 1795 1.1E-5 T 29-03-2018 IPR031325 RHS repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF05593 RHS Repeat 1696 1732 1.5E-5 T 29-03-2018 IPR031325 RHS repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF05593 RHS Repeat 1742 1774 5.5E-5 T 29-03-2018 IPR031325 RHS repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF05593 RHS Repeat 1654 1688 4.4E-7 T 29-03-2018 IPR031325 RHS repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF05593 RHS Repeat 1318 1352 3.6E-5 T 29-03-2018 IPR031325 RHS repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF05593 RHS Repeat 1948 1983 1.6E-6 T 29-03-2018 IPR031325 RHS repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Gene3D G3DSA:2.60.40.1310 477 544 0.0072 T 29-03-2018 THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 2074 2154 6.3E-22 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 141 203 8.3E-10 T 29-03-2018 THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 243 304 1.9E-12 T 29-03-2018 THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 SUPERFAMILY SSF69318 82 409 5.23E-43 T 29-03-2018 THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Gene3D G3DSA:2.60.40.10 692 767 6.1E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Gene3D G3DSA:2.40.50.70 566 621 0.01 T 29-03-2018 THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 Gene3D G3DSA:2.40.50.70 768 802 1.2E-4 T 29-03-2018 THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1696 1731 3.5E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1654 1688 2.6E-7 T 29-03-2018 IPR006530 YD repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1419 1455 8.3E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1743 1774 1.7E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1160 1191 5.7E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1275 1315 8.1E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1606 1632 4.5E-7 T 29-03-2018 IPR006530 YD repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1097 1133 8.3E-8 T 29-03-2018 IPR006530 YD repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1120 1153 4.6E-4 T 29-03-2018 IPR006530 YD repeat THSYN_RS15070 04e12a6fe9a2acf3d41a9e23d450c102 2338 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1783 1814 2.4E-6 T 29-03-2018 IPR006530 YD repeat THSYN_RS25045 3a5d221f98921a1ac36891bb6933dde6 268 Gene3D G3DSA:3.40.50.150 1 213 8.2E-30 T 29-03-2018 THSYN_RS25045 3a5d221f98921a1ac36891bb6933dde6 268 SUPERFAMILY SSF53335 4 244 2.28E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS25045 3a5d221f98921a1ac36891bb6933dde6 268 Pfam PF13649 Methyltransferase domain 59 151 1.9E-21 T 29-03-2018 THSYN_RS20615 904cbab8542e20c486c00c83bea7abf3 199 Pfam PF14334 Domain of unknown function (DUF4390) 37 195 8.8E-45 T 29-03-2018 IPR025500 Protein of unknown function DUF4390 THSYN_RS15665 02376f895b408523b204d2d8cb94dcf4 109 Gene3D G3DSA:3.60.60.10 29 102 1.4E-11 T 29-03-2018 THSYN_RS15665 02376f895b408523b204d2d8cb94dcf4 109 SUPERFAMILY SSF56235 29 92 3.4E-10 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS15665 02376f895b408523b204d2d8cb94dcf4 109 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 29 71 5.5E-7 T 29-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal THSYN_RS32065 47b5a774e69647f72ec9745da9deac2d 81 Pfam PF04226 Transglycosylase associated protein 32 79 4.0E-11 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 THSYN_RS13780 e94dbb49ef08f93d66c3228720c1bf63 278 Pfam PF03781 Sulfatase-modifying factor enzyme 1 57 262 1.8E-40 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS13780 e94dbb49ef08f93d66c3228720c1bf63 278 SUPERFAMILY SSF56436 57 263 5.42E-50 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS13780 e94dbb49ef08f93d66c3228720c1bf63 278 Gene3D G3DSA:3.90.1580.10 57 272 4.9E-45 T 29-03-2018 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 SUPERFAMILY SSF53720 18 421 5.69E-64 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 PIRSF PIRSF000099 1 423 5.3E-153 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 24 421 2.6E-138 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 Pfam PF00815 Histidinol dehydrogenase 11 421 6.2E-144 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 422 36.479 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 Gene3D G3DSA:3.40.50.1980 219 366 3.4E-48 T 29-03-2018 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 Gene3D G3DSA:3.40.50.1980 18 218 1.8E-78 T 29-03-2018 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 PRINTS PR00083 Histidinol dehydrogenase signature 163 189 3.8E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 PRINTS PR00083 Histidinol dehydrogenase signature 128 154 3.8E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 PRINTS PR00083 Histidinol dehydrogenase signature 356 374 3.8E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 PRINTS PR00083 Histidinol dehydrogenase signature 24 48 3.8E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 PRINTS PR00083 Histidinol dehydrogenase signature 193 218 3.8E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 PRINTS PR00083 Histidinol dehydrogenase signature 222 243 3.8E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 PRINTS PR00083 Histidinol dehydrogenase signature 244 263 3.8E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THSYN_RS12425 f3bb9871747c141dabb48136fcc167c4 423 PRINTS PR00083 Histidinol dehydrogenase signature 315 340 3.8E-80 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THSYN_RS29510 2879ac4fbc678f4edb1e4b2becb2311d 549 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 87 112 7.6E-28 T 29-03-2018 THSYN_RS29510 2879ac4fbc678f4edb1e4b2becb2311d 549 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 115 135 7.6E-28 T 29-03-2018 THSYN_RS29510 2879ac4fbc678f4edb1e4b2becb2311d 549 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 319 331 7.6E-28 T 29-03-2018 THSYN_RS29510 2879ac4fbc678f4edb1e4b2becb2311d 549 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 230 251 7.6E-28 T 29-03-2018 THSYN_RS29510 2879ac4fbc678f4edb1e4b2becb2311d 549 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 162 183 7.6E-28 T 29-03-2018 THSYN_RS29510 2879ac4fbc678f4edb1e4b2becb2311d 549 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 252 278 7.6E-28 T 29-03-2018 THSYN_RS29510 2879ac4fbc678f4edb1e4b2becb2311d 549 Pfam PF00361 Proton-conducting membrane transporter 138 355 5.2E-47 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS29510 2879ac4fbc678f4edb1e4b2becb2311d 549 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 80 124 1.7E-8 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS02970 862cacc84a07e92c31cfda2f65c25e0d 778 SUPERFAMILY SSF82866 179 391 8.63E-18 T 29-03-2018 THSYN_RS02970 862cacc84a07e92c31cfda2f65c25e0d 778 SUPERFAMILY SSF82866 645 775 1.01E-14 T 29-03-2018 THSYN_RS02970 862cacc84a07e92c31cfda2f65c25e0d 778 Gene3D G3DSA:1.20.1640.10 196 405 9.6E-20 T 29-03-2018 THSYN_RS02970 862cacc84a07e92c31cfda2f65c25e0d 778 Gene3D G3DSA:1.20.1640.10 603 776 3.4E-14 T 29-03-2018 THSYN_RS02970 862cacc84a07e92c31cfda2f65c25e0d 778 Pfam PF03176 MMPL family 171 391 5.3E-17 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 THSYN_RS12525 8a7c13a4fa57132b776b178eed034b11 428 Gene3D G3DSA:3.20.20.70 202 328 3.1E-8 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS12525 8a7c13a4fa57132b776b178eed034b11 428 Pfam PF13353 4Fe-4S single cluster domain 215 349 5.5E-23 T 29-03-2018 THSYN_RS12525 8a7c13a4fa57132b776b178eed034b11 428 SUPERFAMILY SSF102114 227 303 3.01E-7 T 29-03-2018 THSYN_RS12185 898b62a2395306fadb0ef86a9554b70c 394 Gene3D G3DSA:3.40.50.300 2 139 1.2E-4 T 29-03-2018 THSYN_RS12185 898b62a2395306fadb0ef86a9554b70c 394 Pfam PF13173 AAA domain 19 146 7.3E-21 T 29-03-2018 THSYN_RS12185 898b62a2395306fadb0ef86a9554b70c 394 Pfam PF13635 Domain of unknown function (DUF4143) 206 361 1.2E-18 T 29-03-2018 IPR025420 Domain of unknown function DUF4143 THSYN_RS12185 898b62a2395306fadb0ef86a9554b70c 394 Gene3D G3DSA:1.10.10.10 188 270 1.1E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS12185 898b62a2395306fadb0ef86a9554b70c 394 SUPERFAMILY SSF52540 5 147 2.51E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19900 7dc58e7e79c3a48f5edccbecc5010b66 598 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 430 439 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS19900 7dc58e7e79c3a48f5edccbecc5010b66 598 Gene3D G3DSA:1.10.1140.10 450 590 1.9E-19 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS19900 7dc58e7e79c3a48f5edccbecc5010b66 598 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 218 439 3.6E-88 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS19900 7dc58e7e79c3a48f5edccbecc5010b66 598 SUPERFAMILY SSF47917 452 535 3.14E-14 T 29-03-2018 THSYN_RS19900 7dc58e7e79c3a48f5edccbecc5010b66 598 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 87 208 8.4E-41 T 29-03-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS19900 7dc58e7e79c3a48f5edccbecc5010b66 598 Gene3D G3DSA:3.40.50.300 75 439 2.6E-99 T 29-03-2018 THSYN_RS19900 7dc58e7e79c3a48f5edccbecc5010b66 598 SUPERFAMILY SSF50615 4 72 2.2E-5 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS19900 7dc58e7e79c3a48f5edccbecc5010b66 598 SUPERFAMILY SSF52540 190 441 2.44E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19900 7dc58e7e79c3a48f5edccbecc5010b66 598 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 12 71 9.8E-6 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS19900 7dc58e7e79c3a48f5edccbecc5010b66 598 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 5 591 48.061 T 29-03-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS06330 6e5ebda6a858ecaa0a6bde4b3b863987 256 Gene3D G3DSA:3.40.190.10 27 134 1.5E-17 T 29-03-2018 THSYN_RS06330 6e5ebda6a858ecaa0a6bde4b3b863987 256 Gene3D G3DSA:3.40.190.10 135 220 4.3E-14 T 29-03-2018 THSYN_RS06330 6e5ebda6a858ecaa0a6bde4b3b863987 256 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 THSYN_RS06330 6e5ebda6a858ecaa0a6bde4b3b863987 256 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 216 3.0E-24 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS06330 6e5ebda6a858ecaa0a6bde4b3b863987 256 SUPERFAMILY SSF53850 29 215 8.83E-37 T 29-03-2018 THSYN_RS06330 6e5ebda6a858ecaa0a6bde4b3b863987 256 SMART SM00062 37 248 1.2E-20 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS03875 4bfa4ff339327c2d15dfaf2ee791eafa 54 PRINTS PR00163 Rubredoxin signature 33 49 2.6E-8 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 THSYN_RS03875 4bfa4ff339327c2d15dfaf2ee791eafa 54 PRINTS PR00163 Rubredoxin signature 3 19 2.6E-8 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 THSYN_RS03875 4bfa4ff339327c2d15dfaf2ee791eafa 54 SUPERFAMILY SSF57802 1 52 2.36E-21 T 29-03-2018 THSYN_RS03875 4bfa4ff339327c2d15dfaf2ee791eafa 54 PIRSF PIRSF000071 1 54 4.4E-23 T 29-03-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 THSYN_RS03875 4bfa4ff339327c2d15dfaf2ee791eafa 54 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 29-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 THSYN_RS03875 4bfa4ff339327c2d15dfaf2ee791eafa 54 Gene3D G3DSA:2.20.28.10 1 53 3.1E-24 T 29-03-2018 THSYN_RS03875 4bfa4ff339327c2d15dfaf2ee791eafa 54 Pfam PF00301 Rubredoxin 4 49 1.0E-20 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 THSYN_RS30055 b88708be2e9fcfd9c40daf41494297d1 1659 SUPERFAMILY SSF55874 35 147 3.87E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS30055 b88708be2e9fcfd9c40daf41494297d1 1659 Gene3D G3DSA:3.30.565.10 11 346 3.1E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS08700 15595266f65bbf211a0f63fd47a6dfb3 154 TIGRFAM TIGR00754 bfr: bacterioferritin 1 153 1.4E-60 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08700 15595266f65bbf211a0f63fd47a6dfb3 154 Gene3D G3DSA:1.20.1260.10 1 148 3.9E-25 T 29-03-2018 IPR012347 Ferritin-related THSYN_RS08700 15595266f65bbf211a0f63fd47a6dfb3 154 PIRSF PIRSF002560 1 154 1.4E-55 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08700 15595266f65bbf211a0f63fd47a6dfb3 154 Pfam PF00210 Ferritin-like domain 12 141 1.1E-22 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 THSYN_RS08700 15595266f65bbf211a0f63fd47a6dfb3 154 SUPERFAMILY SSF47240 1 153 3.84E-34 T 29-03-2018 IPR009078 Ferritin-like superfamily THSYN_RS08700 15595266f65bbf211a0f63fd47a6dfb3 154 PRINTS PR00601 Bacterioferritin signature 44 64 9.7E-47 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08700 15595266f65bbf211a0f63fd47a6dfb3 154 PRINTS PR00601 Bacterioferritin signature 65 85 9.7E-47 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08700 15595266f65bbf211a0f63fd47a6dfb3 154 PRINTS PR00601 Bacterioferritin signature 23 43 9.7E-47 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08700 15595266f65bbf211a0f63fd47a6dfb3 154 PRINTS PR00601 Bacterioferritin signature 107 127 9.7E-47 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08700 15595266f65bbf211a0f63fd47a6dfb3 154 PRINTS PR00601 Bacterioferritin signature 3 22 9.7E-47 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08700 15595266f65bbf211a0f63fd47a6dfb3 154 PRINTS PR00601 Bacterioferritin signature 128 149 9.7E-47 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS08700 15595266f65bbf211a0f63fd47a6dfb3 154 PRINTS PR00601 Bacterioferritin signature 86 106 9.7E-47 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS07155 dd0cf7b92e3c46da33a1da2eca366c86 346 Gene3D G3DSA:3.40.50.970 22 119 1.3E-25 T 29-03-2018 THSYN_RS07155 dd0cf7b92e3c46da33a1da2eca366c86 346 Gene3D G3DSA:3.40.50.970 120 326 3.1E-36 T 29-03-2018 THSYN_RS07155 dd0cf7b92e3c46da33a1da2eca366c86 346 SUPERFAMILY SSF52518 38 322 2.95E-69 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS07155 dd0cf7b92e3c46da33a1da2eca366c86 346 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 75 238 3.4E-21 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 SUPERFAMILY SSF48452 199 311 1.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 SMART SM00028 233 266 280.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 SMART SM00028 281 314 77.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 SMART SM00028 329 362 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 SMART SM00028 521 554 150.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 SMART SM00028 377 410 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 SMART SM00028 473 506 55.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 SMART SM00028 425 458 42.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 Gene3D G3DSA:1.10.150.200 212 290 4.3E-6 T 29-03-2018 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 Gene3D G3DSA:1.10.150.200 384 419 0.0092 T 29-03-2018 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 Gene3D G3DSA:1.10.150.200 324 383 2.1E-4 T 29-03-2018 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 Gene3D G3DSA:1.25.40.10 291 323 0.0025 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 Gene3D G3DSA:1.20.1250.10 420 492 3.1E-11 T 29-03-2018 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 SUPERFAMILY SSF48452 281 461 1.49E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 SUPERFAMILY SSF48452 496 546 1.49E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 Pfam PF13424 Tetratricopeptide repeat 472 546 2.1E-7 T 29-03-2018 THSYN_RS22170 a41d8dd91362fc74af4fead6f4a4a7d3 596 Gene3D G3DSA:1.25.40.10 493 566 1.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS28225 810f496bafd690018e6fba70722701a8 380 Gene3D G3DSA:2.40.50.100 164 362 1.9E-9 T 29-03-2018 THSYN_RS28225 810f496bafd690018e6fba70722701a8 380 Gene3D G3DSA:1.10.287.470 119 162 3.5E-14 T 29-03-2018 THSYN_RS28225 810f496bafd690018e6fba70722701a8 380 SUPERFAMILY SSF111369 51 280 1.1E-26 T 29-03-2018 THSYN_RS28225 810f496bafd690018e6fba70722701a8 380 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 47 359 5.1E-72 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS28225 810f496bafd690018e6fba70722701a8 380 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 63 276 1.4E-22 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS28225 810f496bafd690018e6fba70722701a8 380 Gene3D G3DSA:2.40.50.100 62 118 1.7E-15 T 29-03-2018 THSYN_RS03140 91035db2fc88023c62eedbc72f1ccb27 89 SUPERFAMILY SSF46565 6 72 4.19E-21 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS03140 91035db2fc88023c62eedbc72f1ccb27 89 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 29-03-2018 IPR018253 DnaJ domain, conserved site THSYN_RS03140 91035db2fc88023c62eedbc72f1ccb27 89 PRINTS PR00625 DnaJ domain signature 27 42 1.1E-9 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS03140 91035db2fc88023c62eedbc72f1ccb27 89 PRINTS PR00625 DnaJ domain signature 9 27 1.1E-9 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS03140 91035db2fc88023c62eedbc72f1ccb27 89 Pfam PF00226 DnaJ domain 7 66 5.8E-20 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS03140 91035db2fc88023c62eedbc72f1ccb27 89 Gene3D G3DSA:1.10.287.110 2 71 1.3E-22 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS03140 91035db2fc88023c62eedbc72f1ccb27 89 SMART SM00271 6 61 7.0E-19 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS24595 ce0a704e8fccdec9ffeab765ddc03704 214 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 164 1.3E-36 T 29-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS03020 63091b4af3c5cfaeadae815cf17f6892 397 Gene3D G3DSA:3.40.47.10 252 397 7.7E-47 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS03020 63091b4af3c5cfaeadae815cf17f6892 397 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 246 354 1.7E-28 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal THSYN_RS03020 63091b4af3c5cfaeadae815cf17f6892 397 SUPERFAMILY SSF53901 215 396 6.83E-50 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS03020 63091b4af3c5cfaeadae815cf17f6892 397 SMART SM00825 Beta-ketoacyl synthase 38 397 1.2E-10 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain THSYN_RS03020 63091b4af3c5cfaeadae815cf17f6892 397 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site THSYN_RS03020 63091b4af3c5cfaeadae815cf17f6892 397 Gene3D G3DSA:3.40.47.10 2 244 5.7E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS03020 63091b4af3c5cfaeadae815cf17f6892 397 SUPERFAMILY SSF53901 6 241 7.78E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS03020 63091b4af3c5cfaeadae815cf17f6892 397 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 96 239 9.7E-23 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal THSYN_RS15265 f37e10a1f1d54b307ccb172988eb7641 70 Gene3D G3DSA:2.160.20.50 13 68 2.7E-4 T 29-03-2018 THSYN_RS22750 8b61496fa681f5fa2a7b580b9a2f4374 329 Gene3D G3DSA:3.90.550.10 2 264 6.0E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22750 8b61496fa681f5fa2a7b580b9a2f4374 329 Pfam PF00535 Glycosyl transferase family 2 10 125 4.7E-12 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS22750 8b61496fa681f5fa2a7b580b9a2f4374 329 SUPERFAMILY SSF53448 9 223 1.88E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS02525 7e569fc5daad938932a29768e1488fa7 145 Gene3D G3DSA:3.55.40.10 29 144 7.9E-7 T 29-03-2018 THSYN_RS02525 7e569fc5daad938932a29768e1488fa7 145 SUPERFAMILY SSF54523 1 121 5.26E-11 T 29-03-2018 THSYN_RS02525 7e569fc5daad938932a29768e1488fa7 145 Pfam PF12019 Type II transport protein GspH 34 132 5.3E-7 T 29-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THSYN_RS24265 83346fdee6bd9e7faf0e2efde4ea573d 288 Gene3D G3DSA:3.40.50.150 55 265 2.6E-12 T 29-03-2018 THSYN_RS24265 83346fdee6bd9e7faf0e2efde4ea573d 288 SUPERFAMILY SSF53335 133 255 5.17E-14 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS24265 83346fdee6bd9e7faf0e2efde4ea573d 288 Pfam PF13847 Methyltransferase domain 152 248 1.1E-6 T 29-03-2018 IPR025714 Methyltransferase domain THSYN_RS03085 0d586067fccf947b76fcb66db1995304 343 SUPERFAMILY SSF52540 68 205 2.33E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03085 0d586067fccf947b76fcb66db1995304 343 Gene3D G3DSA:3.40.50.300 7 233 3.8E-8 T 29-03-2018 THSYN_RS17090 455514c50f47a96b17d9be270ee2b352 343 Gene3D G3DSA:3.40.50.2000 15 173 1.3E-11 T 29-03-2018 THSYN_RS17090 455514c50f47a96b17d9be270ee2b352 343 Pfam PF13439 Glycosyltransferase Family 4 18 160 1.1E-15 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS17090 455514c50f47a96b17d9be270ee2b352 343 Pfam PF13692 Glycosyl transferases group 1 174 296 1.4E-22 T 29-03-2018 THSYN_RS17090 455514c50f47a96b17d9be270ee2b352 343 SUPERFAMILY SSF53756 15 335 3.9E-62 T 29-03-2018 THSYN_RS17090 455514c50f47a96b17d9be270ee2b352 343 Gene3D G3DSA:3.40.50.2000 174 318 1.3E-30 T 29-03-2018 THSYN_RS14130 7e759513c57f32ebda1af72bfa64b1cc 102 SUPERFAMILY SSF56436 15 61 4.71E-17 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS14130 7e759513c57f32ebda1af72bfa64b1cc 102 Pfam PF03781 Sulfatase-modifying factor enzyme 1 9 58 2.8E-15 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS14130 7e759513c57f32ebda1af72bfa64b1cc 102 Gene3D G3DSA:3.90.1580.10 6 97 3.0E-17 T 29-03-2018 THSYN_RS18425 b8917863e8bde1f51181d7b43e803d28 331 Hamap MF_00313 Glutaminase [glsA]. 17 319 41.103 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 THSYN_RS18425 b8917863e8bde1f51181d7b43e803d28 331 Gene3D G3DSA:3.40.710.10 13 321 7.8E-107 T 29-03-2018 THSYN_RS18425 b8917863e8bde1f51181d7b43e803d28 331 SUPERFAMILY SSF56601 19 319 6.61E-104 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS18425 b8917863e8bde1f51181d7b43e803d28 331 TIGRFAM TIGR03814 Gln_ase: glutaminase A 26 319 1.7E-103 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 THSYN_RS18425 b8917863e8bde1f51181d7b43e803d28 331 Pfam PF04960 Glutaminase 35 319 2.4E-101 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 THSYN_RS10450 4b7fab0bb9e47d8ce8c5c6462e282419 347 PRINTS PR00164 ABC-2 type transport system membrane protein signature 234 258 6.3E-5 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THSYN_RS10450 4b7fab0bb9e47d8ce8c5c6462e282419 347 PRINTS PR00164 ABC-2 type transport system membrane protein signature 271 290 6.3E-5 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THSYN_RS10450 4b7fab0bb9e47d8ce8c5c6462e282419 347 PRINTS PR00164 ABC-2 type transport system membrane protein signature 291 310 6.3E-5 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THSYN_RS10450 4b7fab0bb9e47d8ce8c5c6462e282419 347 Pfam PF12698 ABC-2 family transporter protein 25 342 4.0E-26 T 29-03-2018 THSYN_RS23860 35d9b296dd1ed9f4522fdf74557995a4 105 SMART SM00739 3 30 4.1E-4 T 29-03-2018 IPR005824 KOW THSYN_RS23860 35d9b296dd1ed9f4522fdf74557995a4 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 103 1.6E-36 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23860 35d9b296dd1ed9f4522fdf74557995a4 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 97 19.367 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23860 35d9b296dd1ed9f4522fdf74557995a4 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 29-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23860 35d9b296dd1ed9f4522fdf74557995a4 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 102 3.7E-25 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23860 35d9b296dd1ed9f4522fdf74557995a4 105 SUPERFAMILY SSF50104 3 102 8.53E-31 T 29-03-2018 IPR008991 Translation protein SH3-like domain THSYN_RS23860 35d9b296dd1ed9f4522fdf74557995a4 105 Pfam PF00467 KOW motif 6 35 2.1E-5 T 29-03-2018 IPR005824 KOW THSYN_RS23860 35d9b296dd1ed9f4522fdf74557995a4 105 Gene3D G3DSA:2.30.30.30 2 92 6.9E-27 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 THSYN_RS24115 ad3c18e40499191374bfb7b78f647196 107 Pfam PF01909 Nucleotidyltransferase domain 21 100 2.2E-11 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS24115 ad3c18e40499191374bfb7b78f647196 107 Gene3D G3DSA:3.30.460.10 5 107 6.3E-18 T 29-03-2018 THSYN_RS24115 ad3c18e40499191374bfb7b78f647196 107 SUPERFAMILY SSF81301 12 97 6.78E-18 T 29-03-2018 THSYN_RS30570 86a0c27805a44c3d44453feb78e2e812 308 Gene3D G3DSA:3.40.50.150 5 235 5.6E-12 T 29-03-2018 THSYN_RS30570 86a0c27805a44c3d44453feb78e2e812 308 SUPERFAMILY SSF53335 120 231 5.63E-11 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS30570 86a0c27805a44c3d44453feb78e2e812 308 SUPERFAMILY SSF53335 25 92 5.63E-11 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 PIRSF PIRSF000726 58 410 6.6E-141 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 PIRSF PIRSF000726 1 62 9.5E-23 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 Gene3D G3DSA:3.40.1160.10 1 234 3.4E-75 T 29-03-2018 THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 Gene3D G3DSA:3.30.70.260 331 403 2.0E-22 T 29-03-2018 THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 SUPERFAMILY SSF55021 248 325 1.93E-17 T 29-03-2018 THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 Pfam PF13840 ACT domain 339 399 7.4E-14 T 29-03-2018 IPR027795 GATS-like ACT domain THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 59 402 7.8E-117 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 Gene3D G3DSA:3.30.70.260 235 330 2.5E-24 T 29-03-2018 THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 8.8E-130 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 SUPERFAMILY SSF53633 4 241 6.28E-75 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 SUPERFAMILY SSF55021 331 404 2.13E-23 T 29-03-2018 THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 Pfam PF00696 Amino acid kinase family 3 229 4.5E-52 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase THSYN_RS28010 91f944450ff47ea69c44424f08c355f8 412 Pfam PF01842 ACT domain 267 323 6.1E-11 T 29-03-2018 IPR002912 ACT domain THSYN_RS03380 86181110c5069ba9e254d585d01f69f8 318 Pfam PF02705 K+ potassium transporter 1 240 3.4E-76 T 29-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 THSYN_RS08560 cc4424fdf2bf4950fc5de8887a9fb5e6 254 Pfam PF00313 'Cold-shock' DNA-binding domain 17 61 2.8E-8 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THSYN_RS08560 cc4424fdf2bf4950fc5de8887a9fb5e6 254 SMART SM00357 12 76 1.5E-7 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 THSYN_RS08560 cc4424fdf2bf4950fc5de8887a9fb5e6 254 SUPERFAMILY SSF50249 8 75 7.07E-13 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS08560 cc4424fdf2bf4950fc5de8887a9fb5e6 254 Gene3D G3DSA:2.40.50.140 4 88 3.2E-12 T 29-03-2018 THSYN_RS08560 cc4424fdf2bf4950fc5de8887a9fb5e6 254 Pfam PF06961 Protein of unknown function (DUF1294) 165 219 3.7E-22 T 29-03-2018 IPR010718 Protein of unknown function DUF1294 THSYN_RS08560 cc4424fdf2bf4950fc5de8887a9fb5e6 254 ProSitePatterns PS00352 'Cold-shock' domain signature. 24 43 - T 29-03-2018 IPR019844 Cold-shock conserved site THSYN_RS21560 98a8006332e768abf8c2d7d7dca81eca 114 SUPERFAMILY SSF50118 2 113 2.45E-28 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS21560 98a8006332e768abf8c2d7d7dca81eca 114 Gene3D G3DSA:2.30.30.110 1 114 2.1E-25 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS21560 98a8006332e768abf8c2d7d7dca81eca 114 PIRSF PIRSF033490 1 114 3.2E-29 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS21560 98a8006332e768abf8c2d7d7dca81eca 114 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 109 3.9E-22 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS20230 b65ff2bbf832dd3af6fe21a13ed063e2 76 Pfam PF10387 Protein of unknown function (DUF2442) 7 71 6.7E-7 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS20230 b65ff2bbf832dd3af6fe21a13ed063e2 76 Gene3D G3DSA:3.30.2020.10 1 73 2.6E-8 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS20230 b65ff2bbf832dd3af6fe21a13ed063e2 76 SUPERFAMILY SSF143880 2 71 1.05E-7 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS15630 2524f25f9701618e746abe90de4a9361 110 SMART SM00317 10 109 5.0E-5 T 29-03-2018 IPR001214 SET domain GO:0005515 THSYN_RS15630 2524f25f9701618e746abe90de4a9361 110 Pfam PF00856 SET domain 69 106 6.2E-9 T 29-03-2018 IPR001214 SET domain GO:0005515 THSYN_RS15630 2524f25f9701618e746abe90de4a9361 110 SUPERFAMILY SSF82199 8 107 1.31E-19 T 29-03-2018 THSYN_RS15630 2524f25f9701618e746abe90de4a9361 110 Gene3D G3DSA:2.170.270.10 7 110 1.7E-17 T 29-03-2018 THSYN_RS08120 99514ffef4e4072ce85b337482821322 583 Pfam PF01930 Domain of unknown function DUF83 30 225 3.8E-23 T 29-03-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 THSYN_RS08120 99514ffef4e4072ce85b337482821322 583 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 64 568 27.252 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THSYN_RS08120 99514ffef4e4072ce85b337482821322 583 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 251 577 2.9E-78 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THSYN_RS08120 99514ffef4e4072ce85b337482821322 583 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 30 225 1.9E-26 T 29-03-2018 IPR013343 CRISPR-associated protein Cas4 THSYN_RS08120 99514ffef4e4072ce85b337482821322 583 Pfam PF01867 CRISPR associated protein Cas1 251 537 1.6E-93 T 29-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THSYN_RS24255 0d40ae869044f7a78c19a3c4520f4bc4 465 Pfam PF13701 Transposase DDE domain group 1 13 454 8.4E-151 T 29-03-2018 IPR025668 Transposase DDE domain THSYN_RS24255 0d40ae869044f7a78c19a3c4520f4bc4 465 Gene3D G3DSA:3.90.350.10 126 373 3.8E-11 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS18660 0d40ae869044f7a78c19a3c4520f4bc4 465 Pfam PF13701 Transposase DDE domain group 1 13 454 8.4E-151 T 29-03-2018 IPR025668 Transposase DDE domain THSYN_RS18660 0d40ae869044f7a78c19a3c4520f4bc4 465 Gene3D G3DSA:3.90.350.10 126 373 3.8E-11 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS05520 0d40ae869044f7a78c19a3c4520f4bc4 465 Pfam PF13701 Transposase DDE domain group 1 13 454 8.4E-151 T 29-03-2018 IPR025668 Transposase DDE domain THSYN_RS05520 0d40ae869044f7a78c19a3c4520f4bc4 465 Gene3D G3DSA:3.90.350.10 126 373 3.8E-11 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS26255 c1db4dfe065e1af1d00b453290898d9e 373 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 6 199 1.1E-70 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THSYN_RS26255 c1db4dfe065e1af1d00b453290898d9e 373 Gene3D G3DSA:3.90.870.10 1 212 5.0E-94 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain THSYN_RS26255 c1db4dfe065e1af1d00b453290898d9e 373 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 198 6.5E-83 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THSYN_RS26255 c1db4dfe065e1af1d00b453290898d9e 373 PIRSF PIRSF001259 1 372 3.6E-130 T 29-03-2018 THSYN_RS26255 c1db4dfe065e1af1d00b453290898d9e 373 Pfam PF00925 GTP cyclohydrolase II 208 369 4.5E-43 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 THSYN_RS26255 c1db4dfe065e1af1d00b453290898d9e 373 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 38.108 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THSYN_RS26255 c1db4dfe065e1af1d00b453290898d9e 373 SUPERFAMILY SSF55821 3 203 8.24E-85 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain THSYN_RS26255 c1db4dfe065e1af1d00b453290898d9e 373 SUPERFAMILY SSF142695 205 369 8.5E-49 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 THSYN_RS11795 2916f97822531ceb16c4c88fef9083ea 235 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 56 140 6.0E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS11795 2916f97822531ceb16c4c88fef9083ea 235 SUPERFAMILY SSF52540 54 166 1.64E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11795 2916f97822531ceb16c4c88fef9083ea 235 Gene3D G3DSA:3.40.50.300 26 214 5.7E-13 T 29-03-2018 THSYN_RS03860 b05fec90d369be6a2ff391346e9c0446 428 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 425 1.0E-190 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 THSYN_RS03860 b05fec90d369be6a2ff391346e9c0446 428 Pfam PF00202 Aminotransferase class-III 34 396 6.8E-78 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THSYN_RS03860 b05fec90d369be6a2ff391346e9c0446 428 Gene3D G3DSA:3.40.640.10 184 303 1.2E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS03860 b05fec90d369be6a2ff391346e9c0446 428 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 426 105.002 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 THSYN_RS03860 b05fec90d369be6a2ff391346e9c0446 428 Gene3D G3DSA:3.90.1150.10 1 183 3.7E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS03860 b05fec90d369be6a2ff391346e9c0446 428 SUPERFAMILY SSF53383 2 425 1.95E-133 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS03860 b05fec90d369be6a2ff391346e9c0446 428 Gene3D G3DSA:3.90.1150.10 304 428 2.6E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS03860 b05fec90d369be6a2ff391346e9c0446 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 35 228 1.2E-29 T 29-03-2018 IPR003111 Lon, substrate-binding domain THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 SMART SM00464 34 229 1.2E-41 T 29-03-2018 IPR003111 Lon, substrate-binding domain THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 703 711 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 Gene3D G3DSA:2.30.130.40 19 142 2.6E-20 T 29-03-2018 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 SUPERFAMILY SSF54211 621 797 3.15E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 Gene3D G3DSA:3.30.230.10 613 798 2.4E-59 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 Hamap MF_01973 Lon protease [lon]. 35 798 60.638 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 TIGRFAM TIGR00763 lon: endopeptidase La 37 797 1.0E-283 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 Gene3D G3DSA:3.40.50.300 326 533 4.8E-31 T 29-03-2018 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 Gene3D G3DSA:1.10.8.60 534 612 5.7E-27 T 29-03-2018 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 700 719 2.3E-50 T 29-03-2018 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 752 770 2.3E-50 T 29-03-2018 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 729 748 2.3E-50 T 29-03-2018 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 384 403 2.3E-50 T 29-03-2018 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 621 637 2.3E-50 T 29-03-2018 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 Gene3D G3DSA:1.10.4060.10 147 238 3.0E-12 T 29-03-2018 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 SUPERFAMILY SSF88697 35 228 8.95E-25 T 29-03-2018 IPR015947 PUA-like domain THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 SMART SM00382 376 521 6.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 380 517 1.1E-22 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 598 796 1.1E-74 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 SUPERFAMILY SSF52540 337 612 5.36E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS01265 79e4ba826e682a90304ea33aedb7fc3e 799 PIRSF PIRSF001174 21 799 3.9E-281 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 THSYN_RS08045 fea8501a99bce2710d0e2658e60d9965 231 SMART SM00382 26 210 5.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS08045 fea8501a99bce2710d0e2658e60d9965 231 Pfam PF00005 ABC transporter 19 160 2.3E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS08045 fea8501a99bce2710d0e2658e60d9965 231 Gene3D G3DSA:3.40.50.300 1 230 1.4E-55 T 29-03-2018 THSYN_RS08045 fea8501a99bce2710d0e2658e60d9965 231 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 231 1.2E-99 T 29-03-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE THSYN_RS08045 fea8501a99bce2710d0e2658e60d9965 231 SUPERFAMILY SSF52540 2 223 2.05E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27485 4562f35cfe32d8be95fd1b6debc8dfa9 97 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 51 1.4E-9 T 29-03-2018 THSYN_RS27485 4562f35cfe32d8be95fd1b6debc8dfa9 97 Gene3D G3DSA:3.40.1620.10 1 50 1.4E-15 T 29-03-2018 THSYN_RS27485 4562f35cfe32d8be95fd1b6debc8dfa9 97 SUPERFAMILY SSF143120 1 50 1.83E-11 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS27485 4562f35cfe32d8be95fd1b6debc8dfa9 97 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 50 2.4E-13 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS33080 105d2db10f306786aa8fae09bfaff2d3 398 Gene3D G3DSA:1.10.150.130 1 92 9.7E-8 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS33080 105d2db10f306786aa8fae09bfaff2d3 398 SUPERFAMILY SSF56349 110 388 2.18E-38 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS33080 105d2db10f306786aa8fae09bfaff2d3 398 Gene3D G3DSA:1.10.150.130 97 196 6.0E-5 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS33080 105d2db10f306786aa8fae09bfaff2d3 398 Pfam PF00589 Phage integrase family 214 382 2.0E-24 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS33080 105d2db10f306786aa8fae09bfaff2d3 398 Gene3D G3DSA:1.10.443.10 212 390 4.7E-37 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS08810 18cab2f73ec8f232a23bc5ff54b36367 430 Pfam PF11902 Protein of unknown function (DUF3422) 6 426 4.2E-164 T 29-03-2018 IPR021830 Protein of unknown function DUF3422 THSYN_RS08810 18cab2f73ec8f232a23bc5ff54b36367 430 Gene3D G3DSA:3.90.20.10 210 369 4.0E-4 T 29-03-2018 THSYN_RS29500 2ad982c5f302f79f5d2c648b7092ec5d 232 SUPERFAMILY SSF52266 23 198 6.83E-10 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain THSYN_RS29500 2ad982c5f302f79f5d2c648b7092ec5d 232 Gene3D G3DSA:3.40.50.1110 9 231 4.8E-26 T 29-03-2018 THSYN_RS24975 f8bf0e2deaec9d07b177f10eaa735872 419 Gene3D G3DSA:3.40.50.2000 209 399 3.1E-24 T 29-03-2018 THSYN_RS24975 f8bf0e2deaec9d07b177f10eaa735872 419 Pfam PF13579 Glycosyl transferase 4-like domain 20 196 3.6E-15 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS24975 f8bf0e2deaec9d07b177f10eaa735872 419 Pfam PF00534 Glycosyl transferases group 1 219 393 1.6E-8 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS24975 f8bf0e2deaec9d07b177f10eaa735872 419 SUPERFAMILY SSF53756 5 413 4.49E-41 T 29-03-2018 THSYN_RS24975 f8bf0e2deaec9d07b177f10eaa735872 419 Gene3D G3DSA:3.40.50.2000 9 208 8.0E-16 T 29-03-2018 THSYN_RS18810 2fe5c97e9a7ec5a7f31186c0efc5ff74 120 SUPERFAMILY SSF51905 9 111 5.07E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS18810 2fe5c97e9a7ec5a7f31186c0efc5ff74 120 Gene3D G3DSA:3.50.50.60 2 88 6.9E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS17880 9d7dd42feb4eacfc3517434fa8c2ad91 105 SUPERFAMILY SSF54909 2 71 9.49E-12 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel THSYN_RS17880 9d7dd42feb4eacfc3517434fa8c2ad91 105 Gene3D G3DSA:3.30.70.100 1 76 2.0E-11 T 29-03-2018 THSYN_RS17880 9d7dd42feb4eacfc3517434fa8c2ad91 105 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 71 8.3E-11 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain THSYN_RS17670 23fd193940c13c6032ac5345bfc12768 217 Gene3D G3DSA:1.20.58.220 2 106 3.4E-17 T 29-03-2018 THSYN_RS17670 23fd193940c13c6032ac5345bfc12768 217 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 213 5.1E-47 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 THSYN_RS17670 23fd193940c13c6032ac5345bfc12768 217 PIRSF PIRSF003107 2 217 9.2E-52 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 THSYN_RS17670 23fd193940c13c6032ac5345bfc12768 217 SUPERFAMILY SSF109755 5 215 1.15E-50 T 29-03-2018 THSYN_RS17670 23fd193940c13c6032ac5345bfc12768 217 Gene3D G3DSA:1.20.58.220 107 215 5.1E-19 T 29-03-2018 THSYN_RS17670 23fd193940c13c6032ac5345bfc12768 217 Pfam PF01895 PhoU domain 16 101 3.7E-16 T 29-03-2018 IPR026022 PhoU domain THSYN_RS17670 23fd193940c13c6032ac5345bfc12768 217 Pfam PF01895 PhoU domain 119 205 1.4E-12 T 29-03-2018 IPR026022 PhoU domain THSYN_RS29970 49943665b9064c9fbf04910e4b14e30e 306 SUPERFAMILY SSF56349 93 283 1.56E-34 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS29970 49943665b9064c9fbf04910e4b14e30e 306 Gene3D G3DSA:1.10.443.10 79 281 6.6E-21 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS29970 49943665b9064c9fbf04910e4b14e30e 306 SUPERFAMILY SSF47823 38 76 7.45E-7 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal THSYN_RS29970 49943665b9064c9fbf04910e4b14e30e 306 Pfam PF00589 Phage integrase family 228 278 5.9E-8 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS13095 2d4a1c56cd568f1e3538ef4696ce402d 290 Pfam PF05685 Putative restriction endonuclease 28 173 5.1E-23 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS13095 2d4a1c56cd568f1e3538ef4696ce402d 290 Gene3D G3DSA:3.90.1570.10 22 180 9.5E-31 T 29-03-2018 THSYN_RS13095 2d4a1c56cd568f1e3538ef4696ce402d 290 SUPERFAMILY SSF52980 25 175 4.72E-17 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS25580 5f28bb3293ceb14d24c29a701c6dd070 189 Pfam PF13689 Domain of unknown function (DUF4154) 39 185 1.5E-31 T 29-03-2018 IPR025293 Protein of unknown function DUF4154 THSYN_RS28995 06d4d5bf6099a83f1f1c686fa1bd5a1e 388 Pfam PF13439 Glycosyltransferase Family 4 18 179 6.9E-19 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS28995 06d4d5bf6099a83f1f1c686fa1bd5a1e 388 Gene3D G3DSA:3.40.50.2000 2 193 1.3E-21 T 29-03-2018 THSYN_RS28995 06d4d5bf6099a83f1f1c686fa1bd5a1e 388 Pfam PF13692 Glycosyl transferases group 1 212 350 6.8E-30 T 29-03-2018 THSYN_RS28995 06d4d5bf6099a83f1f1c686fa1bd5a1e 388 SUPERFAMILY SSF53756 7 378 6.28E-72 T 29-03-2018 THSYN_RS28995 06d4d5bf6099a83f1f1c686fa1bd5a1e 388 Gene3D G3DSA:3.40.50.2000 194 363 9.1E-41 T 29-03-2018 THSYN_RS04055 9fe31c7912156ab7c3d815cd044bc705 64 Gene3D G3DSA:1.25.40.10 1 64 7.8E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS04055 9fe31c7912156ab7c3d815cd044bc705 64 SUPERFAMILY SSF48452 5 63 2.54E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS23385 806fdeb61a6a97f8e7a344734f710ff4 173 SUPERFAMILY SSF55021 88 156 5.34E-11 T 29-03-2018 THSYN_RS23385 806fdeb61a6a97f8e7a344734f710ff4 173 SUPERFAMILY SSF55021 1 77 2.64E-14 T 29-03-2018 THSYN_RS23385 806fdeb61a6a97f8e7a344734f710ff4 173 Pfam PF01842 ACT domain 92 132 1.0E-6 T 29-03-2018 IPR002912 ACT domain THSYN_RS23385 806fdeb61a6a97f8e7a344734f710ff4 173 Gene3D G3DSA:3.30.70.260 5 80 5.8E-13 T 29-03-2018 THSYN_RS23385 806fdeb61a6a97f8e7a344734f710ff4 173 Pfam PF13740 ACT domain 7 75 3.3E-11 T 29-03-2018 THSYN_RS23385 806fdeb61a6a97f8e7a344734f710ff4 173 Gene3D G3DSA:3.30.70.260 86 169 1.7E-11 T 29-03-2018 THSYN_RS07250 3ce18936f4f28b3a2537d7ad5fe281ee 831 Gene3D G3DSA:2.60.40.10 431 787 0.11 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS00415 4f04f5d8b4e1685402fa7db95738e9a9 199 Pfam PF09335 SNARE associated Golgi protein 34 160 5.0E-18 T 29-03-2018 IPR032816 SNARE associated Golgi protein THSYN_RS17655 6854e2988b6d22dcae5c837364ddd6c4 245 Pfam PF13489 Methyltransferase domain 37 200 3.4E-16 T 29-03-2018 THSYN_RS17655 6854e2988b6d22dcae5c837364ddd6c4 245 SUPERFAMILY SSF53335 24 236 1.07E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS17655 6854e2988b6d22dcae5c837364ddd6c4 245 Gene3D G3DSA:3.40.50.150 17 217 1.4E-26 T 29-03-2018 THSYN_RS22015 e1983e29c7d844724d432cefedce6ceb 296 Pfam PF01148 Cytidylyltransferase family 15 288 4.2E-51 T 29-03-2018 THSYN_RS22015 e1983e29c7d844724d432cefedce6ceb 296 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 249 275 - T 29-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 THSYN_RS00635 a1b664f516291e6cdf7a118e37ca6a9c 77 SUPERFAMILY SSF89447 7 69 1.41E-10 T 29-03-2018 THSYN_RS00635 a1b664f516291e6cdf7a118e37ca6a9c 77 SMART SM00966 10 50 0.0015 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS00635 a1b664f516291e6cdf7a118e37ca6a9c 77 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 54 2.6E-8 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS00635 a1b664f516291e6cdf7a118e37ca6a9c 77 Gene3D G3DSA:2.10.260.10 1 76 1.4E-4 T 29-03-2018 THSYN_RS31430 615ce1bf12cabf6a6290074d4eb6cba1 308 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 175 194 6.5E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS31430 615ce1bf12cabf6a6290074d4eb6cba1 308 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 6.5E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS31430 615ce1bf12cabf6a6290074d4eb6cba1 308 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 6.5E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS31430 615ce1bf12cabf6a6290074d4eb6cba1 308 Pfam PF00106 short chain dehydrogenase 15 215 6.1E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS31430 615ce1bf12cabf6a6290074d4eb6cba1 308 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 162 190 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THSYN_RS31430 615ce1bf12cabf6a6290074d4eb6cba1 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 4.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS31430 615ce1bf12cabf6a6290074d4eb6cba1 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 4.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS31430 615ce1bf12cabf6a6290074d4eb6cba1 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 4.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS31430 615ce1bf12cabf6a6290074d4eb6cba1 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 4.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS31430 615ce1bf12cabf6a6290074d4eb6cba1 308 Gene3D G3DSA:3.40.50.720 1 308 1.8E-56 T 29-03-2018 THSYN_RS31430 615ce1bf12cabf6a6290074d4eb6cba1 308 SUPERFAMILY SSF51735 11 220 5.4E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS31025 ff6be6581a362982f28dd4fe7561b154 75 Pfam PF10049 Protein of unknown function (DUF2283) 2 50 1.6E-14 T 29-03-2018 IPR019270 Protein of unknown function DUF2283 THSYN_RS26920 a7b0834c3ff16e5419bfb7a5db5e4344 121 Gene3D G3DSA:3.30.429.10 1 117 9.4E-26 T 29-03-2018 THSYN_RS26920 a7b0834c3ff16e5419bfb7a5db5e4344 121 Pfam PF14552 Tautomerase enzyme 38 113 5.9E-23 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 THSYN_RS26920 a7b0834c3ff16e5419bfb7a5db5e4344 121 SUPERFAMILY SSF55331 2 119 2.55E-28 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily THSYN_RS32020 057984edbd4ae3c85a11a3a0b21019cb 229 Gene3D G3DSA:3.20.20.70 147 227 9.9E-8 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS32020 057984edbd4ae3c85a11a3a0b21019cb 229 Gene3D G3DSA:3.20.20.70 1 137 1.1E-8 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS32020 057984edbd4ae3c85a11a3a0b21019cb 229 SUPERFAMILY SSF51366 1 224 1.88E-25 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THSYN_RS32020 057984edbd4ae3c85a11a3a0b21019cb 229 Pfam PF00977 Histidine biosynthesis protein 3 218 4.3E-16 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 THSYN_RS32785 7975820ee58473e7ad25c88ca5a340d0 141 Pfam PF01850 PIN domain 4 120 3.5E-13 T 29-03-2018 IPR002716 PIN domain THSYN_RS32785 7975820ee58473e7ad25c88ca5a340d0 141 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 131 10.889 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS32785 7975820ee58473e7ad25c88ca5a340d0 141 SUPERFAMILY SSF88723 1 135 2.8E-25 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS32785 7975820ee58473e7ad25c88ca5a340d0 141 Gene3D G3DSA:3.40.50.1010 3 137 9.9E-22 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS03980 781c9bfd50b7a0f58925e0329d4a8d2a 72 SUPERFAMILY SSF50249 1 70 9.06E-29 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS03980 781c9bfd50b7a0f58925e0329d4a8d2a 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 4.2E-28 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 THSYN_RS03980 781c9bfd50b7a0f58925e0329d4a8d2a 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.501 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 THSYN_RS03980 781c9bfd50b7a0f58925e0329d4a8d2a 72 Gene3D G3DSA:2.40.50.140 1 72 2.5E-36 T 29-03-2018 THSYN_RS03980 781c9bfd50b7a0f58925e0329d4a8d2a 72 SMART SM00316 4 72 1.7E-4 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS03980 781c9bfd50b7a0f58925e0329d4a8d2a 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 1.3E-38 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 THSYN_RS00675 72ce6fa4da82bfb5deacd626d3f7a277 323 Gene3D G3DSA:2.60.200.20 4 118 3.0E-25 T 29-03-2018 THSYN_RS00675 72ce6fa4da82bfb5deacd626d3f7a277 323 SMART SM00471 143 278 3.5E-15 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS00675 72ce6fa4da82bfb5deacd626d3f7a277 323 SMART SM00240 44 94 9.3E-12 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THSYN_RS00675 72ce6fa4da82bfb5deacd626d3f7a277 323 SUPERFAMILY SSF109604 128 309 4.71E-39 T 29-03-2018 THSYN_RS00675 72ce6fa4da82bfb5deacd626d3f7a277 323 Gene3D G3DSA:1.10.3210.10 119 312 1.5E-48 T 29-03-2018 THSYN_RS00675 72ce6fa4da82bfb5deacd626d3f7a277 323 SUPERFAMILY SSF49879 21 118 3.06E-26 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 THSYN_RS00675 72ce6fa4da82bfb5deacd626d3f7a277 323 TIGRFAM TIGR00277 HDIG: HDIG domain 147 237 5.0E-8 T 29-03-2018 IPR006675 HDIG domain THSYN_RS00675 72ce6fa4da82bfb5deacd626d3f7a277 323 Pfam PF00498 FHA domain 45 108 3.8E-18 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THSYN_RS00675 72ce6fa4da82bfb5deacd626d3f7a277 323 Pfam PF01966 HD domain 148 269 3.3E-23 T 29-03-2018 IPR006674 HD domain THSYN_RS04200 af5b62410d713433d36592d66c85f8ea 320 Pfam PF00005 ABC transporter 18 161 1.4E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS04200 af5b62410d713433d36592d66c85f8ea 320 Gene3D G3DSA:3.40.50.300 1 231 2.2E-65 T 29-03-2018 THSYN_RS04200 af5b62410d713433d36592d66c85f8ea 320 SMART SM00382 26 208 7.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS04200 af5b62410d713433d36592d66c85f8ea 320 SUPERFAMILY SSF52540 1 218 1.92E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13030 0373c78194f2d84240d75034866d50ee 196 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 118 194 1.5E-22 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 THSYN_RS13030 0373c78194f2d84240d75034866d50ee 196 PRINTS PR01217 Proline rich extensin signature 1 12 3.3E-11 T 29-03-2018 THSYN_RS13030 0373c78194f2d84240d75034866d50ee 196 PRINTS PR01217 Proline rich extensin signature 47 63 3.3E-11 T 29-03-2018 THSYN_RS13030 0373c78194f2d84240d75034866d50ee 196 PRINTS PR01217 Proline rich extensin signature 64 81 3.3E-11 T 29-03-2018 THSYN_RS13030 0373c78194f2d84240d75034866d50ee 196 PRINTS PR01217 Proline rich extensin signature 26 47 3.3E-11 T 29-03-2018 THSYN_RS13030 0373c78194f2d84240d75034866d50ee 196 SUPERFAMILY SSF74653 111 192 1.03E-23 T 29-03-2018 THSYN_RS13030 0373c78194f2d84240d75034866d50ee 196 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 116 194 9.4E-23 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 THSYN_RS13030 0373c78194f2d84240d75034866d50ee 196 Gene3D G3DSA:3.30.1150.10 27 196 1.3E-20 T 29-03-2018 THSYN_RS02440 382311c91f3a714966374dd13fbd0dc5 448 SUPERFAMILY SSF53756 230 445 1.06E-41 T 29-03-2018 THSYN_RS02440 382311c91f3a714966374dd13fbd0dc5 448 Gene3D G3DSA:3.40.50.2000 275 435 1.1E-28 T 29-03-2018 THSYN_RS02440 382311c91f3a714966374dd13fbd0dc5 448 Pfam PF13692 Glycosyl transferases group 1 286 416 1.4E-18 T 29-03-2018 THSYN_RS31380 0906dd03115e9c6b9446af09991bf722 274 SUPERFAMILY SSF81483 3 273 5.5E-113 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31380 0906dd03115e9c6b9446af09991bf722 274 Gene3D G3DSA:1.20.85.10 4 115 5.3E-35 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31380 0906dd03115e9c6b9446af09991bf722 274 TIGRFAM TIGR01157 pufL: photosynthetic reaction center L subunit 35 273 6.0E-133 T 29-03-2018 IPR005871 Photosynthetic reaction centre, L subunit GO:0019684|GO:0030077|GO:0045156 THSYN_RS31380 0906dd03115e9c6b9446af09991bf722 274 ProSitePatterns PS00244 Photosynthetic reaction center proteins signature. 167 193 - T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31380 0906dd03115e9c6b9446af09991bf722 274 Gene3D G3DSA:1.20.85.10 118 260 1.8E-49 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31380 0906dd03115e9c6b9446af09991bf722 274 PRINTS PR00256 Bacterial photosynthetic reaction centre signature 34 55 7.4E-63 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31380 0906dd03115e9c6b9446af09991bf722 274 PRINTS PR00256 Bacterial photosynthetic reaction centre signature 117 139 7.4E-63 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31380 0906dd03115e9c6b9446af09991bf722 274 PRINTS PR00256 Bacterial photosynthetic reaction centre signature 173 199 7.4E-63 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31380 0906dd03115e9c6b9446af09991bf722 274 PRINTS PR00256 Bacterial photosynthetic reaction centre signature 84 112 7.4E-63 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31380 0906dd03115e9c6b9446af09991bf722 274 PRINTS PR00256 Bacterial photosynthetic reaction centre signature 226 251 7.4E-63 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS31380 0906dd03115e9c6b9446af09991bf722 274 Pfam PF00124 Photosynthetic reaction centre protein 30 272 6.9E-97 T 29-03-2018 IPR000484 Photosynthetic reaction centre, L/M GO:0009772|GO:0019684|GO:0045156 MetaCyc: PWY-101 THSYN_RS19660 be9f7cd68e7ca8d0c8d023ace7c530b8 493 Pfam PF05872 Bacterial protein of unknown function (DUF853) 10 487 1.5E-215 T 29-03-2018 IPR033186 Helicase HerA-like C-terminal THSYN_RS19660 be9f7cd68e7ca8d0c8d023ace7c530b8 493 Gene3D G3DSA:3.40.50.300 2 344 3.9E-28 T 29-03-2018 THSYN_RS19660 be9f7cd68e7ca8d0c8d023ace7c530b8 493 SUPERFAMILY SSF52540 93 377 9.74E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19660 be9f7cd68e7ca8d0c8d023ace7c530b8 493 SUPERFAMILY SSF52540 10 66 9.74E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05045 8c66adff38b57c9d662a4feb1af0b03b 87 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 39 2.7E-6 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS05045 8c66adff38b57c9d662a4feb1af0b03b 87 SUPERFAMILY SSF143120 1 42 1.44E-6 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS05045 8c66adff38b57c9d662a4feb1af0b03b 87 Gene3D G3DSA:3.40.1620.10 1 79 4.4E-9 T 29-03-2018 THSYN_RS01290 0d6ba5d98e8456749a4cce6a823ddb87 256 Gene3D G3DSA:3.40.50.300 13 230 2.9E-6 T 29-03-2018 THSYN_RS01290 0d6ba5d98e8456749a4cce6a823ddb87 256 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 22 205 4.4E-7 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS24210 82bcd9d5711a7ef64cd146813d1a2a42 576 TIGRFAM TIGR04456 LruC_dom: LruC domain 321 565 9.3E-62 T 29-03-2018 IPR031025 LruC domain THSYN_RS24210 82bcd9d5711a7ef64cd146813d1a2a42 576 Pfam PF13448 Domain of unknown function (DUF4114) 180 268 1.8E-20 T 29-03-2018 IPR025193 Domain of unknown function DUF4114 THSYN_RS24210 82bcd9d5711a7ef64cd146813d1a2a42 576 Pfam PF16130 Domain of unknown function (DUF4842) 354 564 9.8E-41 T 29-03-2018 IPR032295 Domain of unknown function DUF4842 THSYN_RS07625 20877ea721e30969a2e09f7df3fd3065 209 PIRSF PIRSF006170 1 208 2.9E-54 T 29-03-2018 IPR026039 Uncharacterised protein family UPF0070 THSYN_RS07625 20877ea721e30969a2e09f7df3fd3065 209 Gene3D G3DSA:1.25.40.10 44 203 3.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS07625 20877ea721e30969a2e09f7df3fd3065 209 Pfam PF09976 Tetratricopeptide repeat-like domain 15 206 2.3E-52 T 29-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 THSYN_RS07625 20877ea721e30969a2e09f7df3fd3065 209 SUPERFAMILY SSF48452 93 191 2.61E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS04010 4a9a16d4f9343efc0151b70752bb4f01 103 Gene3D G3DSA:1.10.10.710 22 85 1.5E-20 T 29-03-2018 THSYN_RS04010 4a9a16d4f9343efc0151b70752bb4f01 103 Pfam PF07130 YebG protein 2 76 4.1E-22 T 29-03-2018 IPR009813 Uncharacterised protein family YebG THSYN_RS29840 91d65cdccf60e03cbfaade0afbe9be64 189 SUPERFAMILY SSF52980 2 164 1.34E-24 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS29840 91d65cdccf60e03cbfaade0afbe9be64 189 Gene3D G3DSA:3.90.1570.10 2 188 1.8E-43 T 29-03-2018 THSYN_RS29840 91d65cdccf60e03cbfaade0afbe9be64 189 Pfam PF05685 Putative restriction endonuclease 12 171 1.7E-33 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS29535 47cc886f4d72f637745cbfeae06b0b75 57 SUPERFAMILY SSF54913 2 53 3.89E-13 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THSYN_RS29535 47cc886f4d72f637745cbfeae06b0b75 57 Pfam PF02641 Uncharacterized ACR, COG1993 2 51 1.5E-9 T 29-03-2018 IPR003793 Domain of unknown function DUF190 THSYN_RS29535 47cc886f4d72f637745cbfeae06b0b75 57 Gene3D G3DSA:3.30.70.120 1 55 7.2E-13 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THSYN_RS00075 f8935174205b326b3f6d052f0c306bd5 158 Gene3D G3DSA:3.40.1280.10 1 158 1.0E-37 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THSYN_RS00075 f8935174205b326b3f6d052f0c306bd5 158 Pfam PF00588 SpoU rRNA Methylase family 2 142 1.4E-29 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 THSYN_RS00075 f8935174205b326b3f6d052f0c306bd5 158 PIRSF PIRSF029256 1 154 2.4E-59 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 THSYN_RS00075 f8935174205b326b3f6d052f0c306bd5 158 SUPERFAMILY SSF75217 1 152 2.81E-42 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases THSYN_RS00075 f8935174205b326b3f6d052f0c306bd5 158 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 31.136 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 THSYN_RS22765 19bc37224c8579731219c2e158b31037 347 Pfam PF00535 Glycosyl transferase family 2 26 153 6.3E-34 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS22765 19bc37224c8579731219c2e158b31037 347 SUPERFAMILY SSF53448 23 157 4.56E-55 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22765 19bc37224c8579731219c2e158b31037 347 SUPERFAMILY SSF53448 191 256 4.56E-55 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22765 19bc37224c8579731219c2e158b31037 347 Gene3D G3DSA:3.90.550.10 11 281 4.0E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS28795 aacc0b2d189f432b7b94367603dff988 229 Pfam PF02586 SOS response associated peptidase (SRAP) 1 214 1.2E-66 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) THSYN_RS28795 aacc0b2d189f432b7b94367603dff988 229 SUPERFAMILY SSF143081 2 225 1.57E-72 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) THSYN_RS28795 aacc0b2d189f432b7b94367603dff988 229 Gene3D G3DSA:3.90.1680.10 1 228 4.4E-76 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) THSYN_RS10630 adc656f4758164e4be17f771216391c3 713 SUPERFAMILY SSF52540 402 521 2.17E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10630 adc656f4758164e4be17f771216391c3 713 SUPERFAMILY SSF52540 549 581 2.17E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10630 adc656f4758164e4be17f771216391c3 713 Gene3D G3DSA:3.40.50.300 398 583 1.6E-18 T 29-03-2018 THSYN_RS10630 adc656f4758164e4be17f771216391c3 713 Pfam PF07728 AAA domain (dynein-related subfamily) 415 574 2.5E-12 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THSYN_RS02530 19bd7569e4f06476344bea5dc571971f 142 Gene3D G3DSA:3.30.700.10 25 141 4.7E-24 T 29-03-2018 THSYN_RS02530 19bd7569e4f06476344bea5dc571971f 142 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 11 142 5.7E-47 T 29-03-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 THSYN_RS02530 19bd7569e4f06476344bea5dc571971f 142 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 31 4.8E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS02530 19bd7569e4f06476344bea5dc571971f 142 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS02530 19bd7569e4f06476344bea5dc571971f 142 PRINTS PR00813 Bacterial general secretion pathway protein G signature 11 36 1.2E-14 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THSYN_RS02530 19bd7569e4f06476344bea5dc571971f 142 PRINTS PR00813 Bacterial general secretion pathway protein G signature 47 65 1.2E-14 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THSYN_RS02530 19bd7569e4f06476344bea5dc571971f 142 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 31 4.9E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS02530 19bd7569e4f06476344bea5dc571971f 142 Pfam PF08334 Type II secretion system (T2SS), protein G 34 141 1.4E-40 T 29-03-2018 IPR013545 Type II secretion system protein G THSYN_RS02530 19bd7569e4f06476344bea5dc571971f 142 SUPERFAMILY SSF54523 39 142 1.94E-33 T 29-03-2018 THSYN_RS21025 077492fdf59ee25a654ef8c79c2413e9 554 SMART SM00490 350 439 3.4E-20 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS21025 077492fdf59ee25a654ef8c79c2413e9 554 SMART SM00487 61 294 0.0018 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS21025 077492fdf59ee25a654ef8c79c2413e9 554 Gene3D G3DSA:3.40.50.300 49 285 3.2E-16 T 29-03-2018 THSYN_RS21025 077492fdf59ee25a654ef8c79c2413e9 554 SUPERFAMILY SSF52540 170 264 1.72E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21025 077492fdf59ee25a654ef8c79c2413e9 554 SUPERFAMILY SSF52540 77 132 1.72E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21025 077492fdf59ee25a654ef8c79c2413e9 554 SUPERFAMILY SSF52540 305 449 1.72E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21025 077492fdf59ee25a654ef8c79c2413e9 554 Pfam PF00270 DEAD/DEAH box helicase 67 262 1.6E-12 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS21025 077492fdf59ee25a654ef8c79c2413e9 554 Pfam PF00271 Helicase conserved C-terminal domain 339 438 3.0E-14 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS21025 077492fdf59ee25a654ef8c79c2413e9 554 Gene3D G3DSA:3.40.50.300 318 474 1.0E-22 T 29-03-2018 THSYN_RS09850 f1ede4f336591832e33166ac5e191656 432 SUPERFAMILY SSF116734 213 426 2.45E-29 T 29-03-2018 THSYN_RS09850 f1ede4f336591832e33166ac5e191656 432 Pfam PF01420 Type I restriction modification DNA specificity domain 2 181 5.6E-8 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS09850 f1ede4f336591832e33166ac5e191656 432 Pfam PF01420 Type I restriction modification DNA specificity domain 290 391 7.4E-6 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS09850 f1ede4f336591832e33166ac5e191656 432 Gene3D G3DSA:3.90.220.20 2 178 3.8E-18 T 29-03-2018 THSYN_RS09850 f1ede4f336591832e33166ac5e191656 432 Gene3D G3DSA:3.90.220.20 179 404 2.9E-22 T 29-03-2018 THSYN_RS09850 f1ede4f336591832e33166ac5e191656 432 SUPERFAMILY SSF116734 3 201 9.32E-29 T 29-03-2018 THSYN_RS00845 b72eaeefa2ee6612ddfac73874da89ed 245 Pfam PF02754 Cysteine-rich domain 133 217 2.2E-12 T 29-03-2018 IPR004017 Cysteine-rich domain THSYN_RS00845 b72eaeefa2ee6612ddfac73874da89ed 245 Pfam PF02754 Cysteine-rich domain 5 86 2.5E-12 T 29-03-2018 IPR004017 Cysteine-rich domain THSYN_RS07710 7f0bc6e91730893f081edec3c34d9d26 37 Pfam PF14367 Domain of unknown function (DUF4411) 10 37 4.3E-7 T 29-03-2018 IPR016541 Uncharacterised conserved protein UCP008505 THSYN_RS14505 61d93aeea5ec07ce1ef1a0ab658313bb 479 PIRSF PIRSF006603 26 479 9.1E-62 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 THSYN_RS14505 61d93aeea5ec07ce1ef1a0ab658313bb 479 TIGRFAM TIGR00797 matE: MATE efflux family protein 39 434 1.8E-55 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 THSYN_RS14505 61d93aeea5ec07ce1ef1a0ab658313bb 479 Pfam PF01554 MatE 39 196 1.5E-16 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 THSYN_RS14505 61d93aeea5ec07ce1ef1a0ab658313bb 479 Pfam PF01554 MatE 276 418 1.6E-15 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 THSYN_RS18800 e23697107f315dfe8ad536d4b490138e 390 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 130 374 9.0E-30 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS18800 e23697107f315dfe8ad536d4b490138e 390 Gene3D G3DSA:3.30.70.150 12 121 1.0E-16 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS18800 e23697107f315dfe8ad536d4b490138e 390 Gene3D G3DSA:3.20.20.110 123 390 1.7E-77 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS18800 e23697107f315dfe8ad536d4b490138e 390 SUPERFAMILY SSF51649 121 386 2.75E-71 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS18800 e23697107f315dfe8ad536d4b490138e 390 SUPERFAMILY SSF54966 7 119 4.45E-13 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS20165 a138eda31d9c47834eb50f0dc578c870 224 SMART SM00855 4 158 2.0E-17 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THSYN_RS20165 a138eda31d9c47834eb50f0dc578c870 224 Gene3D G3DSA:3.40.50.1240 2 208 6.1E-55 T 29-03-2018 IPR029033 Histidine phosphatase superfamily THSYN_RS20165 a138eda31d9c47834eb50f0dc578c870 224 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 199 4.9E-58 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THSYN_RS20165 a138eda31d9c47834eb50f0dc578c870 224 PIRSF PIRSF000709 1 169 2.3E-19 T 29-03-2018 THSYN_RS20165 a138eda31d9c47834eb50f0dc578c870 224 SUPERFAMILY SSF53254 1 208 8.25E-59 T 29-03-2018 IPR029033 Histidine phosphatase superfamily THSYN_RS05170 78b9d24d9b8b1605582d2c1cc0167a93 643 Gene3D G3DSA:3.40.50.720 417 539 1.5E-18 T 29-03-2018 THSYN_RS05170 78b9d24d9b8b1605582d2c1cc0167a93 643 Pfam PF02254 TrkA-N domain 426 539 1.0E-22 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 THSYN_RS05170 78b9d24d9b8b1605582d2c1cc0167a93 643 SUPERFAMILY SSF51735 423 563 4.18E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS05170 78b9d24d9b8b1605582d2c1cc0167a93 643 Pfam PF00999 Sodium/hydrogen exchanger family 9 397 6.3E-56 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 THSYN_RS05170 78b9d24d9b8b1605582d2c1cc0167a93 643 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 12 307 1.8E-75 T 29-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 THSYN_RS05170 78b9d24d9b8b1605582d2c1cc0167a93 643 Gene3D G3DSA:1.20.91.10 252 339 2.2E-10 T 29-03-2018 THSYN_RS00315 6f6dd7cab9075e5bb424cd42ef854fda 505 SUPERFAMILY SSF51445 3 493 1.86E-162 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS00315 6f6dd7cab9075e5bb424cd42ef854fda 505 Gene3D G3DSA:3.20.20.80 1 498 1.7E-165 T 29-03-2018 THSYN_RS00315 6f6dd7cab9075e5bb424cd42ef854fda 505 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 2 409 1.9E-97 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 THSYN_RS00315 6f6dd7cab9075e5bb424cd42ef854fda 505 Pfam PF02446 4-alpha-glucanotransferase 9 476 1.0E-148 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 THSYN_RS29305 f90da3092c8d2892df54eb7d68810d2a 328 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 37 98 6.4E-5 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS29305 f90da3092c8d2892df54eb7d68810d2a 328 SUPERFAMILY SSF47823 33 130 3.14E-30 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal THSYN_RS29305 f90da3092c8d2892df54eb7d68810d2a 328 SUPERFAMILY SSF56349 132 323 1.29E-40 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS29305 f90da3092c8d2892df54eb7d68810d2a 328 Pfam PF00589 Phage integrase family 139 316 2.4E-14 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS29305 f90da3092c8d2892df54eb7d68810d2a 328 Gene3D G3DSA:1.10.150.130 28 131 6.5E-15 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS29305 f90da3092c8d2892df54eb7d68810d2a 328 Gene3D G3DSA:1.10.443.10 132 319 5.2E-27 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS01195 63e9d526eed6ab88f6212ac3700db512 197 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 24 174 1.3E-22 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 THSYN_RS01195 63e9d526eed6ab88f6212ac3700db512 197 Gene3D G3DSA:3.60.21.10 11 191 2.2E-19 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS01195 63e9d526eed6ab88f6212ac3700db512 197 SUPERFAMILY SSF56300 23 186 1.27E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS02225 9007e89e6df211f26b909735935cdcc7 328 Gene3D G3DSA:3.40.50.2300 46 161 2.5E-25 T 29-03-2018 THSYN_RS02225 9007e89e6df211f26b909735935cdcc7 328 Pfam PF13407 Periplasmic binding protein domain 48 309 4.9E-57 T 29-03-2018 IPR025997 Periplasmic binding protein THSYN_RS02225 9007e89e6df211f26b909735935cdcc7 328 Gene3D G3DSA:3.40.50.2300 162 328 1.2E-40 T 29-03-2018 THSYN_RS02225 9007e89e6df211f26b909735935cdcc7 328 SUPERFAMILY SSF53822 47 327 1.06E-72 T 29-03-2018 IPR028082 Periplasmic binding protein-like I THSYN_RS02455 3d40244c69f86e4a6d103cd8e1c5847c 426 Pfam PF01943 Polysaccharide biosynthesis protein 3 280 1.3E-21 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 THSYN_RS24590 61efc37e9c6113e109bd49bb9ac63dbc 101 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 2 101 20.003 T 29-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 THSYN_RS24590 61efc37e9c6113e109bd49bb9ac63dbc 101 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 96 5.9E-25 T 29-03-2018 THSYN_RS00045 a00ada0ef5389d697aa07e33f9110b79 467 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 257 272 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 THSYN_RS00045 a00ada0ef5389d697aa07e33f9110b79 467 ProSitePatterns PS00180 Glutamine synthetase signature 1. 48 66 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 THSYN_RS00045 a00ada0ef5389d697aa07e33f9110b79 467 Pfam PF00120 Glutamine synthetase, catalytic domain 100 464 5.7E-133 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THSYN_RS00045 a00ada0ef5389d697aa07e33f9110b79 467 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 3 466 3.2E-200 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THSYN_RS00045 a00ada0ef5389d697aa07e33f9110b79 467 SUPERFAMILY SSF54368 2 98 1.44E-37 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THSYN_RS00045 a00ada0ef5389d697aa07e33f9110b79 467 SUPERFAMILY SSF55931 100 466 2.45E-135 T 29-03-2018 THSYN_RS00045 a00ada0ef5389d697aa07e33f9110b79 467 SMART SM01230 100 377 1.1E-145 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THSYN_RS00045 a00ada0ef5389d697aa07e33f9110b79 467 Gene3D G3DSA:3.10.20.70 1 102 4.1E-29 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THSYN_RS00045 a00ada0ef5389d697aa07e33f9110b79 467 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 12 93 1.7E-30 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THSYN_RS00045 a00ada0ef5389d697aa07e33f9110b79 467 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 384 396 - T 29-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THSYN_RS00045 a00ada0ef5389d697aa07e33f9110b79 467 Gene3D G3DSA:3.30.590.10 103 455 1.2E-117 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 THSYN_RS19695 115f525d93a1b1c443912c89c5b89765 224 Pfam PF01618 MotA/TolQ/ExbB proton channel family 81 208 6.2E-43 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 THSYN_RS19695 115f525d93a1b1c443912c89c5b89765 224 TIGRFAM TIGR02796 tolQ: protein TolQ 6 220 1.9E-89 T 29-03-2018 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 THSYN_RS32930 495547eb8e1acf1aa167af852a5aa5e6 232 Gene3D G3DSA:3.40.630.40 2 141 1.7E-15 T 29-03-2018 THSYN_RS32930 495547eb8e1acf1aa167af852a5aa5e6 232 SUPERFAMILY SSF53187 11 137 7.22E-11 T 29-03-2018 THSYN_RS32930 495547eb8e1acf1aa167af852a5aa5e6 232 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 12 134 1.3E-10 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 THSYN_RS32930 495547eb8e1acf1aa167af852a5aa5e6 232 SMART SM00646 15 134 8.6E-4 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 THSYN_RS01530 9136a5038df9ed0f2dfd788dc23e0948 226 SUPERFAMILY SSF55718 31 135 1.12E-6 T 29-03-2018 IPR003033 SCP2 sterol-binding domain THSYN_RS01530 9136a5038df9ed0f2dfd788dc23e0948 226 Pfam PF02036 SCP-2 sterol transfer family 31 128 5.6E-12 T 29-03-2018 IPR003033 SCP2 sterol-binding domain THSYN_RS13950 324f887ef3171f08e737e3acb16245c3 387 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 162 378 4.8E-33 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS13950 324f887ef3171f08e737e3acb16245c3 387 SUPERFAMILY SSF111369 153 301 6.41E-8 T 29-03-2018 THSYN_RS13950 324f887ef3171f08e737e3acb16245c3 387 Gene3D G3DSA:3.90.1170.30 145 211 4.0E-4 T 29-03-2018 THSYN_RS13950 324f887ef3171f08e737e3acb16245c3 387 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 57 296 1.5E-14 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS13950 324f887ef3171f08e737e3acb16245c3 387 Gene3D G3DSA:2.40.50.100 54 120 1.1E-9 T 29-03-2018 THSYN_RS13950 324f887ef3171f08e737e3acb16245c3 387 Gene3D G3DSA:2.40.50.100 212 313 3.0E-7 T 29-03-2018 THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 Gene3D G3DSA:3.40.50.300 1 247 1.7E-48 T 29-03-2018 THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 Gene3D G3DSA:1.10.287.370 248 316 0.43 T 29-03-2018 THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 SMART SM00382 337 504 1.1E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 SMART SM00382 26 223 9.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 Gene3D G3DSA:1.20.58.60 508 632 6.9E-4 T 29-03-2018 THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 Gene3D G3DSA:3.40.50.300 317 507 2.9E-44 T 29-03-2018 THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 Pfam PF00005 ABC transporter 18 178 3.9E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 Pfam PF00005 ABC transporter 328 459 8.2E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 Pfam PF12848 ABC transporter 217 296 1.7E-30 T 29-03-2018 IPR032781 ABC-transporter extension domain THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 SUPERFAMILY SSF52540 295 509 1.2E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 SUPERFAMILY SSF52540 119 257 1.2E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00330 5f09eca37841960761309930d71cd95a 633 SUPERFAMILY SSF52540 2 92 1.2E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08285 dda249af8b6073eeaf8d1814a0f2bdcb 357 Gene3D G3DSA:1.10.287.470 136 194 5.9E-9 T 29-03-2018 THSYN_RS08285 dda249af8b6073eeaf8d1814a0f2bdcb 357 SUPERFAMILY SSF111369 137 194 6.54E-5 T 29-03-2018 THSYN_RS08285 dda249af8b6073eeaf8d1814a0f2bdcb 357 SUPERFAMILY SSF111369 204 284 6.15E-7 T 29-03-2018 THSYN_RS08285 dda249af8b6073eeaf8d1814a0f2bdcb 357 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 57 307 4.5E-14 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS08285 dda249af8b6073eeaf8d1814a0f2bdcb 357 Gene3D G3DSA:1.20.1600.10 200 333 9.4E-19 T 29-03-2018 THSYN_RS08285 dda249af8b6073eeaf8d1814a0f2bdcb 357 Gene3D G3DSA:2.40.50.100 67 129 3.2E-12 T 29-03-2018 THSYN_RS08285 dda249af8b6073eeaf8d1814a0f2bdcb 357 SUPERFAMILY SSF111369 60 125 2.62E-7 T 29-03-2018 THSYN_RS08285 dda249af8b6073eeaf8d1814a0f2bdcb 357 TIGRFAM TIGR02971 heterocyst_DevB: ABC exporter membrane fusion protein, DevB family 56 337 8.9E-39 T 29-03-2018 IPR014315 ABC transporter, membrane fusion protein, DevB type THSYN_RS20895 cb14331b6c0a3e766a00cec6506faca3 498 Gene3D G3DSA:3.20.20.70 15 266 1.7E-16 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS20895 cb14331b6c0a3e766a00cec6506faca3 498 Pfam PF03445 Putative nucleotidyltransferase DUF294 183 318 4.5E-45 T 29-03-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 THSYN_RS20895 cb14331b6c0a3e766a00cec6506faca3 498 SMART SM00116 40 89 0.93 T 29-03-2018 IPR000644 CBS domain THSYN_RS20895 cb14331b6c0a3e766a00cec6506faca3 498 SMART SM00116 106 154 2.9 T 29-03-2018 IPR000644 CBS domain THSYN_RS20895 cb14331b6c0a3e766a00cec6506faca3 498 SUPERFAMILY SSF54631 36 154 3.28E-17 T 29-03-2018 THSYN_RS20895 cb14331b6c0a3e766a00cec6506faca3 498 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 355 496 3.8E-35 T 29-03-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding THSYN_RS02050 423709e2c1cf8a9ca43cbd12b3810924 149 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain THSYN_RS02050 423709e2c1cf8a9ca43cbd12b3810924 149 SUPERFAMILY SSF55804 4 146 6.93E-38 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 THSYN_RS02050 423709e2c1cf8a9ca43cbd12b3810924 149 Gene3D G3DSA:3.40.930.10 2 147 5.2E-35 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 THSYN_RS02050 423709e2c1cf8a9ca43cbd12b3810924 149 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 145 2.3E-33 T 29-03-2018 IPR002178 PTS EIIA type-2 domain THSYN_RS19200 a3687dc48a98f8b2a55d4c82a157d54c 215 Pfam PF00005 ABC transporter 29 78 3.8E-9 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS19200 a3687dc48a98f8b2a55d4c82a157d54c 215 Pfam PF00005 ABC transporter 115 151 1.5E-5 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS19200 a3687dc48a98f8b2a55d4c82a157d54c 215 Gene3D G3DSA:3.40.50.300 15 208 1.2E-36 T 29-03-2018 THSYN_RS19200 a3687dc48a98f8b2a55d4c82a157d54c 215 SUPERFAMILY SSF52540 8 205 7.95E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19200 a3687dc48a98f8b2a55d4c82a157d54c 215 SMART SM00382 36 202 8.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS00350 30b820627c185f61e48377c4b712180b 279 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 120 279 5.3E-17 T 29-03-2018 IPR010239 Conserved hypothetical protein CHP02001 THSYN_RS00350 30b820627c185f61e48377c4b712180b 279 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 8 86 3.4E-20 T 29-03-2018 IPR010239 Conserved hypothetical protein CHP02001 THSYN_RS00350 30b820627c185f61e48377c4b712180b 279 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 29 278 3.4E-33 T 29-03-2018 IPR010239 Conserved hypothetical protein CHP02001 THSYN_RS07485 10a5657e830d8e83587e2662f4d7a462 162 PIRSF PIRSF000239 1 160 8.0E-23 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THSYN_RS07485 10a5657e830d8e83587e2662f4d7a462 162 Gene3D G3DSA:3.40.30.10 1 156 4.0E-33 T 29-03-2018 THSYN_RS07485 10a5657e830d8e83587e2662f4d7a462 162 SUPERFAMILY SSF52833 3 154 7.09E-45 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS07485 10a5657e830d8e83587e2662f4d7a462 162 Pfam PF00578 AhpC/TSA family 6 133 4.7E-32 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THSYN_RS24525 89f0ccf0ad6175ec8cf1727fd25bfa73 328 SUPERFAMILY SSF50129 6 141 1.67E-36 T 29-03-2018 IPR011032 GroES-like THSYN_RS24525 89f0ccf0ad6175ec8cf1727fd25bfa73 328 Pfam PF00107 Zinc-binding dehydrogenase 161 273 7.2E-13 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THSYN_RS24525 89f0ccf0ad6175ec8cf1727fd25bfa73 328 SMART SM00829 15 326 3.5E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THSYN_RS24525 89f0ccf0ad6175ec8cf1727fd25bfa73 328 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 6 327 1.9E-116 T 29-03-2018 IPR014188 Acrylyl-CoA reductase AcuI THSYN_RS24525 89f0ccf0ad6175ec8cf1727fd25bfa73 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 89 2.2E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THSYN_RS24525 89f0ccf0ad6175ec8cf1727fd25bfa73 328 Gene3D G3DSA:3.40.50.720 162 269 9.5E-16 T 29-03-2018 THSYN_RS24525 89f0ccf0ad6175ec8cf1727fd25bfa73 328 SUPERFAMILY SSF51735 118 292 2.05E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS24525 89f0ccf0ad6175ec8cf1727fd25bfa73 328 Gene3D G3DSA:3.90.180.10 4 161 6.8E-32 T 29-03-2018 THSYN_RS27620 9620465ab5de2a35fa6ee0362b7ab25f 222 Gene3D G3DSA:2.150.10.10 56 222 3.7E-5 T 29-03-2018 THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 Gene3D G3DSA:1.20.120.160 305 498 7.5E-26 T 29-03-2018 THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 Gene3D G3DSA:3.30.565.10 44 192 7.0E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 SMART SM00387 74 190 2.3E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 SUPERFAMILY SSF52172 206 330 8.97E-36 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 Gene3D G3DSA:3.40.50.2300 208 304 4.7E-24 T 29-03-2018 THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 174 187 8.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 150 168 8.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 133 143 8.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 PRINTS PR00344 Bacterial sensor protein C-terminal signature 115 129 8.1E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 SUPERFAMILY SSF47226 309 322 3.66E-15 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 SUPERFAMILY SSF47226 371 448 3.66E-15 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 Pfam PF01627 Hpt domain 403 475 1.3E-8 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 Pfam PF00072 Response regulator receiver domain 211 325 3.8E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 SUPERFAMILY SSF55874 39 190 8.77E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 74 188 1.1E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS07130 1f1d5356aad91b03a696c960042db518 572 SMART SM00448 208 326 2.3E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS31980 fe61b09dc5636f429ad4498f2fc21a26 74 Pfam PF14261 Domain of unknown function (DUF4351) 18 64 9.0E-6 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS02475 3107cdbc665c70228eb53b1cf1888d40 404 Gene3D G3DSA:3.40.50.150 177 363 2.1E-28 T 29-03-2018 THSYN_RS02475 3107cdbc665c70228eb53b1cf1888d40 404 Pfam PF05050 Methyltransferase FkbM domain 196 354 6.2E-14 T 29-03-2018 IPR006342 Methyltransferase FkbM THSYN_RS02475 3107cdbc665c70228eb53b1cf1888d40 404 SUPERFAMILY SSF53335 168 356 3.07E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02475 3107cdbc665c70228eb53b1cf1888d40 404 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 193 319 1.0E-23 T 29-03-2018 IPR006342 Methyltransferase FkbM THSYN_RS20020 8720331368444ebf15ff10b997dfae7f 199 Pfam PF03352 Methyladenine glycosylase 11 186 2.2E-76 T 29-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 THSYN_RS20020 8720331368444ebf15ff10b997dfae7f 199 SUPERFAMILY SSF48150 7 188 2.59E-76 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 THSYN_RS20020 8720331368444ebf15ff10b997dfae7f 199 Gene3D G3DSA:1.10.340.30 6 187 5.4E-80 T 29-03-2018 THSYN_RS20020 8720331368444ebf15ff10b997dfae7f 199 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 8 185 3.0E-76 T 29-03-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 THSYN_RS18120 d365f15352951fe613d32a831615828d 418 Gene3D G3DSA:3.40.50.300 1 132 8.7E-6 T 29-03-2018 THSYN_RS18120 d365f15352951fe613d32a831615828d 418 Gene3D G3DSA:3.40.50.300 165 333 1.6E-8 T 29-03-2018 THSYN_RS18120 d365f15352951fe613d32a831615828d 418 SUPERFAMILY SSF52540 3 310 3.75E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS18120 d365f15352951fe613d32a831615828d 418 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 24 309 8.0E-25 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS15815 e9fcc5bb69d315526eed72ce2b60220a 456 Gene3D G3DSA:3.40.50.1000 219 456 3.1E-20 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS15815 e9fcc5bb69d315526eed72ce2b60220a 456 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 221 414 4.1E-17 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 THSYN_RS15815 e9fcc5bb69d315526eed72ce2b60220a 456 SUPERFAMILY SSF56784 220 449 1.9E-39 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS15815 e9fcc5bb69d315526eed72ce2b60220a 456 Pfam PF02358 Trehalose-phosphatase 222 437 6.6E-36 T 29-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 THSYN_RS15815 e9fcc5bb69d315526eed72ce2b60220a 456 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 216 449 8.8E-39 T 29-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 THSYN_RS15680 84383a8a39a2275beb495b83c3b97260 336 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 33 298 5.9E-45 T 29-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal THSYN_RS15680 84383a8a39a2275beb495b83c3b97260 336 Gene3D G3DSA:3.60.60.10 33 323 3.9E-70 T 29-03-2018 THSYN_RS15680 84383a8a39a2275beb495b83c3b97260 336 SUPERFAMILY SSF56235 33 304 1.0E-66 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS16805 bdaa8d823ae02c670189c1840ea92f01 117 PIRSF PIRSF029826 1 115 4.8E-42 T 29-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 THSYN_RS16805 bdaa8d823ae02c670189c1840ea92f01 117 Pfam PF12643 MazG-like family 35 106 4.9E-12 T 29-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 THSYN_RS16805 bdaa8d823ae02c670189c1840ea92f01 117 SUPERFAMILY SSF101386 3 110 1.12E-33 T 29-03-2018 THSYN_RS16805 bdaa8d823ae02c670189c1840ea92f01 117 Gene3D G3DSA:1.10.4010.10 1 107 5.8E-26 T 29-03-2018 THSYN_RS02460 fc138d5dddd5a00b0da67d4cde50201d 251 Gene3D G3DSA:3.40.50.150 18 174 2.5E-8 T 29-03-2018 THSYN_RS02460 fc138d5dddd5a00b0da67d4cde50201d 251 SUPERFAMILY SSF53335 58 164 2.47E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS06195 f83e890092e24f78a34e06fd0fcee90f 61 Gene3D G3DSA:1.20.890.30 21 56 1.2E-14 T 29-03-2018 THSYN_RS06195 f83e890092e24f78a34e06fd0fcee90f 61 SUPERFAMILY SSF47598 2 51 8.89E-11 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS06195 f83e890092e24f78a34e06fd0fcee90f 61 Pfam PF08681 Protein of unknown function (DUF1778) 1 55 5.2E-15 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 THSYN_RS09705 66cd7558ba826332b00de00ea71ae961 140 SUPERFAMILY SSF52980 8 131 8.58E-22 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS09705 66cd7558ba826332b00de00ea71ae961 140 Gene3D G3DSA:3.90.1570.10 20 133 1.1E-16 T 29-03-2018 THSYN_RS09705 66cd7558ba826332b00de00ea71ae961 140 Pfam PF05685 Putative restriction endonuclease 68 127 2.1E-10 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS21430 be07969ec9165cd4e7391aa2958fa3f0 394 SUPERFAMILY SSF116734 168 390 5.23E-38 T 29-03-2018 THSYN_RS21430 be07969ec9165cd4e7391aa2958fa3f0 394 SUPERFAMILY SSF116734 22 169 1.8E-22 T 29-03-2018 THSYN_RS21430 be07969ec9165cd4e7391aa2958fa3f0 394 Gene3D G3DSA:1.10.287.1120 351 392 6.9E-6 T 29-03-2018 THSYN_RS21430 be07969ec9165cd4e7391aa2958fa3f0 394 Pfam PF01420 Type I restriction modification DNA specificity domain 252 351 1.3E-6 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS21430 be07969ec9165cd4e7391aa2958fa3f0 394 Gene3D G3DSA:3.90.220.20 2 143 1.2E-14 T 29-03-2018 THSYN_RS21430 be07969ec9165cd4e7391aa2958fa3f0 394 Gene3D G3DSA:3.90.220.20 144 350 1.2E-29 T 29-03-2018 THSYN_RS00820 83b50079d87c31af3f057182ecc26f37 423 SUPERFAMILY SSF53448 13 286 1.71E-80 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS00820 83b50079d87c31af3f057182ecc26f37 423 SUPERFAMILY SSF53448 353 369 1.71E-80 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS00820 83b50079d87c31af3f057182ecc26f37 423 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 22 41 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 THSYN_RS00820 83b50079d87c31af3f057182ecc26f37 423 Gene3D G3DSA:3.90.550.10 9 292 3.3E-58 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS00820 83b50079d87c31af3f057182ecc26f37 423 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 357 389 0.0016 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS00820 83b50079d87c31af3f057182ecc26f37 423 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 16 389 3.3E-157 T 29-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 THSYN_RS00820 83b50079d87c31af3f057182ecc26f37 423 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 13 416 51.357 T 29-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 THSYN_RS00820 83b50079d87c31af3f057182ecc26f37 423 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 109 117 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 THSYN_RS00820 83b50079d87c31af3f057182ecc26f37 423 Gene3D G3DSA:2.160.10.10 307 406 1.3E-12 T 29-03-2018 THSYN_RS00820 83b50079d87c31af3f057182ecc26f37 423 Pfam PF00483 Nucleotidyl transferase 18 281 1.1E-63 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THSYN_RS00820 83b50079d87c31af3f057182ecc26f37 423 SUPERFAMILY SSF51161 302 414 1.52E-21 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS18140 d2537d6f8ca8c1438d236e8932b8b4fa 210 SUPERFAMILY SSF52266 33 204 1.83E-38 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain THSYN_RS18140 d2537d6f8ca8c1438d236e8932b8b4fa 210 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 36 192 2.9E-26 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain THSYN_RS18140 d2537d6f8ca8c1438d236e8932b8b4fa 210 Gene3D G3DSA:3.40.50.1110 19 207 1.8E-36 T 29-03-2018 THSYN_RS07595 2c3f2d332275f3ab08d6b0750ab616ac 120 PIRSF PIRSF000169 1 110 1.0E-21 T 29-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 THSYN_RS07595 2c3f2d332275f3ab08d6b0750ab616ac 120 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 6 97 4.6E-10 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07595 2c3f2d332275f3ab08d6b0750ab616ac 120 SUPERFAMILY SSF81343 3 107 4.36E-22 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07595 2c3f2d332275f3ab08d6b0750ab616ac 120 Gene3D G3DSA:1.20.1300.10 1 110 1.1E-16 T 29-03-2018 THSYN_RS07595 2c3f2d332275f3ab08d6b0750ab616ac 120 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 6 107 6.7E-26 T 29-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 THSYN_RS17200 a66f0dc0ca33fe5097d26d126735b763 175 Pfam PF00156 Phosphoribosyl transferase domain 42 152 5.8E-17 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THSYN_RS17200 a66f0dc0ca33fe5097d26d126735b763 175 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 172 37.666 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 THSYN_RS17200 a66f0dc0ca33fe5097d26d126735b763 175 Gene3D G3DSA:3.40.50.2020 1 174 7.3E-44 T 29-03-2018 THSYN_RS17200 a66f0dc0ca33fe5097d26d126735b763 175 SUPERFAMILY SSF53271 4 172 2.76E-54 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like THSYN_RS17200 a66f0dc0ca33fe5097d26d126735b763 175 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 171 4.2E-70 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 THSYN_RS02245 b2908e8c06e3bbd944f176ea889934f8 786 SUPERFAMILY SSF52540 542 586 7.63E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02245 b2908e8c06e3bbd944f176ea889934f8 786 SUPERFAMILY SSF52540 449 512 7.63E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02245 b2908e8c06e3bbd944f176ea889934f8 786 Gene3D G3DSA:3.40.50.300 435 692 1.8E-4 T 29-03-2018 THSYN_RS02245 b2908e8c06e3bbd944f176ea889934f8 786 SUPERFAMILY SSF47413 323 377 2.55E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS02245 b2908e8c06e3bbd944f176ea889934f8 786 Gene3D G3DSA:3.40.50.1820 21 274 9.9E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS02245 b2908e8c06e3bbd944f176ea889934f8 786 SUPERFAMILY SSF53474 24 193 1.66E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS02245 b2908e8c06e3bbd944f176ea889934f8 786 Gene3D G3DSA:1.10.260.40 319 400 3.6E-7 T 29-03-2018 THSYN_RS25270 858543026c1c0aa9425891421b8ce9ab 324 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 2 324 47.385 T 29-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 THSYN_RS25270 858543026c1c0aa9425891421b8ce9ab 324 SUPERFAMILY SSF51735 3 316 1.74E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS25270 858543026c1c0aa9425891421b8ce9ab 324 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 316 2.0E-115 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS25270 858543026c1c0aa9425891421b8ce9ab 324 Gene3D G3DSA:3.40.50.720 2 184 4.3E-27 T 29-03-2018 THSYN_RS25270 858543026c1c0aa9425891421b8ce9ab 324 Gene3D G3DSA:3.90.25.10 190 310 4.2E-40 T 29-03-2018 THSYN_RS13800 92d1680a7c202a5581b08dd44cc47836 244 Gene3D G3DSA:2.40.50.140 167 244 1.7E-23 T 29-03-2018 THSYN_RS13800 92d1680a7c202a5581b08dd44cc47836 244 Pfam PF01957 NfeD-like C-terminal, partner-binding 99 234 6.2E-35 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain THSYN_RS13800 92d1680a7c202a5581b08dd44cc47836 244 SUPERFAMILY SSF141322 169 235 3.53E-11 T 29-03-2018 THSYN_RS06095 3abf346ce0292f768563bf83da95d3da 217 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS06095 3abf346ce0292f768563bf83da95d3da 217 Pfam PF00005 ABC transporter 17 165 5.1E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS06095 3abf346ce0292f768563bf83da95d3da 217 Gene3D G3DSA:3.40.50.300 1 216 5.1E-58 T 29-03-2018 THSYN_RS06095 3abf346ce0292f768563bf83da95d3da 217 SMART SM00382 26 214 2.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS06095 3abf346ce0292f768563bf83da95d3da 217 SUPERFAMILY SSF52540 1 211 2.73E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03480 3aa52536262db056c3ac910969582059 347 SUPERFAMILY SSF53098 206 304 2.85E-7 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS03480 3aa52536262db056c3ac910969582059 347 Pfam PF13358 DDE superfamily endonuclease 170 309 1.8E-24 T 29-03-2018 THSYN_RS03480 3aa52536262db056c3ac910969582059 347 SUPERFAMILY SSF46689 28 130 1.79E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS03480 3aa52536262db056c3ac910969582059 347 Gene3D G3DSA:3.30.420.10 169 338 6.7E-13 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS04325 3aa52536262db056c3ac910969582059 347 SUPERFAMILY SSF53098 206 304 2.85E-7 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS04325 3aa52536262db056c3ac910969582059 347 Pfam PF13358 DDE superfamily endonuclease 170 309 1.8E-24 T 29-03-2018 THSYN_RS04325 3aa52536262db056c3ac910969582059 347 SUPERFAMILY SSF46689 28 130 1.79E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS04325 3aa52536262db056c3ac910969582059 347 Gene3D G3DSA:3.30.420.10 169 338 6.7E-13 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS27750 3aa52536262db056c3ac910969582059 347 SUPERFAMILY SSF53098 206 304 2.85E-7 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS27750 3aa52536262db056c3ac910969582059 347 Pfam PF13358 DDE superfamily endonuclease 170 309 1.8E-24 T 29-03-2018 THSYN_RS27750 3aa52536262db056c3ac910969582059 347 SUPERFAMILY SSF46689 28 130 1.79E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS27750 3aa52536262db056c3ac910969582059 347 Gene3D G3DSA:3.30.420.10 169 338 6.7E-13 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS01460 657dd134fe88f72ec976713add003d7a 533 Pfam PF00962 Adenosine/AMP deaminase 319 465 9.6E-22 T 29-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 THSYN_RS01460 657dd134fe88f72ec976713add003d7a 533 Gene3D G3DSA:3.20.20.140 27 526 2.3E-62 T 29-03-2018 THSYN_RS01460 657dd134fe88f72ec976713add003d7a 533 SUPERFAMILY SSF51556 256 466 3.29E-53 T 29-03-2018 IPR032466 Metal-dependent hydrolase THSYN_RS01460 657dd134fe88f72ec976713add003d7a 533 SUPERFAMILY SSF51556 39 186 3.29E-53 T 29-03-2018 IPR032466 Metal-dependent hydrolase THSYN_RS30600 fc04b649fc7629d52460b87c99c2e427 605 Pfam PF00860 Permease family 52 429 1.0E-31 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THSYN_RS07640 806b6d3a36735d2d2933c61b22d2775f 379 PIRSF PIRSF006004 6 361 3.5E-135 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS07640 806b6d3a36735d2d2933c61b22d2775f 379 Pfam PF04055 Radical SAM superfamily 115 277 1.6E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS07640 806b6d3a36735d2d2933c61b22d2775f 379 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 11 350 69.769 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS07640 806b6d3a36735d2d2933c61b22d2775f 379 SUPERFAMILY SSF102114 109 318 1.96E-12 T 29-03-2018 THSYN_RS07640 806b6d3a36735d2d2933c61b22d2775f 379 Gene3D G3DSA:3.20.20.70 20 350 5.8E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS07640 806b6d3a36735d2d2933c61b22d2775f 379 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 8 354 2.8E-129 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THSYN_RS06340 3f9cd44d46159c3f63a3ba8de99de657 146 SUPERFAMILY SSF54637 14 143 1.46E-22 T 29-03-2018 IPR029069 HotDog domain THSYN_RS06340 3f9cd44d46159c3f63a3ba8de99de657 146 Gene3D G3DSA:3.10.129.10 9 145 6.8E-19 T 29-03-2018 THSYN_RS06340 3f9cd44d46159c3f63a3ba8de99de657 146 Pfam PF13279 Thioesterase-like superfamily 26 135 4.7E-8 T 29-03-2018 THSYN_RS31855 b1a1562138b2137304dc0fc8992667af 783 Gene3D G3DSA:2.120.10.30 304 783 1.4E-50 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS31855 b1a1562138b2137304dc0fc8992667af 783 Pfam PF07995 Glucose / Sorbosone dehydrogenase 329 600 1.9E-32 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase THSYN_RS31855 b1a1562138b2137304dc0fc8992667af 783 SUPERFAMILY SSF50952 426 486 3.4E-23 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 THSYN_RS31855 b1a1562138b2137304dc0fc8992667af 783 SUPERFAMILY SSF50952 528 623 3.4E-23 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 THSYN_RS31855 b1a1562138b2137304dc0fc8992667af 783 SUPERFAMILY SSF50952 752 782 3.4E-23 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 THSYN_RS31855 b1a1562138b2137304dc0fc8992667af 783 SUPERFAMILY SSF50952 654 721 3.4E-23 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 THSYN_RS31855 b1a1562138b2137304dc0fc8992667af 783 SUPERFAMILY SSF50952 316 390 3.4E-23 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 THSYN_RS31855 b1a1562138b2137304dc0fc8992667af 783 Gene3D G3DSA:2.60.120.260 21 222 1.1E-7 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 Pfam PF02824 TGS domain 407 466 2.0E-17 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 SUPERFAMILY SSF81271 394 466 4.58E-19 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 SMART SM00954 254 364 1.2E-59 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 SUPERFAMILY SSF109604 23 209 1.73E-66 T 29-03-2018 THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 SUPERFAMILY SSF55021 651 726 3.47E-10 T 29-03-2018 THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 45 724 1.9E-218 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 Pfam PF13291 ACT domain 649 725 2.7E-18 T 29-03-2018 IPR002912 ACT domain THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 Gene3D G3DSA:3.30.460.10 213 344 2.4E-42 T 29-03-2018 THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 SUPERFAMILY SSF81301 199 411 4.41E-59 T 29-03-2018 THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 SMART SM00471 60 172 6.5E-10 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 Gene3D G3DSA:3.30.70.260 648 728 2.5E-13 T 29-03-2018 THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 Pfam PF13328 HD domain 46 194 1.1E-45 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 Gene3D G3DSA:3.10.20.30 401 474 3.3E-21 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS24885 9076a904418e39b4299f2bdda8cf8137 728 Pfam PF04607 Region found in RelA / SpoT proteins 254 363 1.7E-36 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 THSYN_RS18710 bf15f3b9690798a1a0c04e8bdc0f469a 324 Pfam PF12784 PD-(D/E)XK nuclease family transposase 7 229 6.7E-53 T 29-03-2018 THSYN_RS18710 bf15f3b9690798a1a0c04e8bdc0f469a 324 Gene3D G3DSA:1.20.1000.10 54 321 1.1E-5 T 29-03-2018 THSYN_RS18710 bf15f3b9690798a1a0c04e8bdc0f469a 324 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 8 232 3.9E-32 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA THSYN_RS03305 6697aef3ff6b265cc930975488f56206 192 Pfam PF01420 Type I restriction modification DNA specificity domain 16 163 6.4E-17 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS03305 6697aef3ff6b265cc930975488f56206 192 SUPERFAMILY SSF116734 7 186 1.8E-38 T 29-03-2018 THSYN_RS03305 6697aef3ff6b265cc930975488f56206 192 Gene3D G3DSA:3.90.220.20 1 166 2.4E-23 T 29-03-2018 THSYN_RS20590 80b21474ef0bc0ee5a361c2107caa816 387 Gene3D G3DSA:1.10.150.20 31 113 0.076 T 29-03-2018 THSYN_RS20590 80b21474ef0bc0ee5a361c2107caa816 387 Gene3D G3DSA:1.10.150.20 8 30 0.09 T 29-03-2018 THSYN_RS20590 80b21474ef0bc0ee5a361c2107caa816 387 Gene3D G3DSA:1.10.10.10 303 383 1.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS20590 80b21474ef0bc0ee5a361c2107caa816 387 Pfam PF02481 DNA recombination-mediator protein A 82 285 1.4E-76 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 THSYN_RS20590 80b21474ef0bc0ee5a361c2107caa816 387 SUPERFAMILY SSF102405 90 294 1.53E-43 T 29-03-2018 THSYN_RS20590 80b21474ef0bc0ee5a361c2107caa816 387 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 79 292 1.2E-75 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 THSYN_RS20590 80b21474ef0bc0ee5a361c2107caa816 387 Gene3D G3DSA:3.40.50.450 121 269 3.5E-37 T 29-03-2018 THSYN_RS32430 b3ed6bd6ee2aa58d6db836be02e82834 339 Pfam PF13280 WYL domain 152 330 2.3E-25 T 29-03-2018 IPR026881 WYL domain THSYN_RS26770 7e68144244283dfc9a8182b35bf07f23 85 Gene3D G3DSA:1.10.1220.10 1 79 2.0E-10 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS26770 7e68144244283dfc9a8182b35bf07f23 85 SUPERFAMILY SSF47598 2 60 1.93E-13 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS25030 0a424864d87b9c3694d058b76b092b0c 328 Pfam PF04754 Putative transposase, YhgA-like 3 160 1.9E-29 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS25030 0a424864d87b9c3694d058b76b092b0c 328 Pfam PF14261 Domain of unknown function (DUF4351) 261 301 7.7E-6 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS31795 5b8dbcfc676d82fd49664abf723568e2 164 Gene3D G3DSA:3.40.630.30 21 156 3.7E-17 T 29-03-2018 THSYN_RS31795 5b8dbcfc676d82fd49664abf723568e2 164 SUPERFAMILY SSF55729 12 152 1.08E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS31795 5b8dbcfc676d82fd49664abf723568e2 164 Pfam PF00583 Acetyltransferase (GNAT) family 43 145 1.6E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS20830 4ef9f121d82da3186e36dcb19418f493 360 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 187 206 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site THSYN_RS20830 4ef9f121d82da3186e36dcb19418f493 360 Gene3D G3DSA:3.90.1150.10 258 358 2.4E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS20830 4ef9f121d82da3186e36dcb19418f493 360 SUPERFAMILY SSF53383 1 357 2.32E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS20830 4ef9f121d82da3186e36dcb19418f493 360 PIRSF PIRSF000525 1 360 1.2E-156 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 THSYN_RS20830 4ef9f121d82da3186e36dcb19418f493 360 Gene3D G3DSA:3.40.640.10 16 257 1.8E-29 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS20830 4ef9f121d82da3186e36dcb19418f493 360 Pfam PF00266 Aminotransferase class-V 4 348 2.6E-56 T 29-03-2018 IPR000192 Aminotransferase class V domain THSYN_RS20830 4ef9f121d82da3186e36dcb19418f493 360 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 359 52.147 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 THSYN_RS20830 4ef9f121d82da3186e36dcb19418f493 360 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 359 2.8E-159 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 THSYN_RS19550 f41cc5314b1a7ae6151a87cc4ebb0149 377 Pfam PF00535 Glycosyl transferase family 2 125 248 2.6E-13 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS19550 f41cc5314b1a7ae6151a87cc4ebb0149 377 Gene3D G3DSA:3.90.550.10 77 365 5.7E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS19550 f41cc5314b1a7ae6151a87cc4ebb0149 377 SUPERFAMILY SSF53448 119 272 2.09E-18 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS16410 7111476e233200c0dd446491fad22c71 96 Gene3D G3DSA:1.10.1220.10 2 39 1.2E-5 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS04985 669c94cd1188dcf0531713ec8c613c25 351 Gene3D G3DSA:3.20.20.330 2 351 3.9E-113 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 THSYN_RS04985 669c94cd1188dcf0531713ec8c613c25 351 Pfam PF02574 Homocysteine S-methyltransferase 18 326 5.1E-79 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 THSYN_RS04985 669c94cd1188dcf0531713ec8c613c25 351 SUPERFAMILY SSF82282 8 349 6.02E-101 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 THSYN_RS04985 669c94cd1188dcf0531713ec8c613c25 351 PIRSF PIRSF037505 55 350 5.0E-9 T 29-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 THSYN_RS11155 a90c7db8c39b3c4fdfa963f6a39dae47 573 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 212 334 8.2E-22 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 THSYN_RS11155 a90c7db8c39b3c4fdfa963f6a39dae47 573 SUPERFAMILY SSF52518 379 558 5.18E-52 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS11155 a90c7db8c39b3c4fdfa963f6a39dae47 573 Gene3D G3DSA:3.40.50.970 1 184 9.2E-48 T 29-03-2018 THSYN_RS11155 a90c7db8c39b3c4fdfa963f6a39dae47 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 174 1.6E-49 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THSYN_RS11155 a90c7db8c39b3c4fdfa963f6a39dae47 573 Gene3D G3DSA:3.40.50.970 361 567 2.6E-41 T 29-03-2018 THSYN_RS11155 a90c7db8c39b3c4fdfa963f6a39dae47 573 Gene3D G3DSA:3.40.50.1220 191 360 1.3E-27 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS11155 a90c7db8c39b3c4fdfa963f6a39dae47 573 SUPERFAMILY SSF52467 212 382 6.74E-27 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS11155 a90c7db8c39b3c4fdfa963f6a39dae47 573 SUPERFAMILY SSF52518 1 177 7.99E-44 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS11155 a90c7db8c39b3c4fdfa963f6a39dae47 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 402 549 3.7E-33 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THSYN_RS25795 cbcded3da16ff1100cb6b5e4fa2b293a 129 SUPERFAMILY SSF52833 9 119 1.64E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS25795 cbcded3da16ff1100cb6b5e4fa2b293a 129 PIRSF PIRSF000077 10 118 1.4E-20 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THSYN_RS25795 cbcded3da16ff1100cb6b5e4fa2b293a 129 PRINTS PR00421 Thioredoxin family signature 82 93 3.9E-5 T 29-03-2018 THSYN_RS25795 cbcded3da16ff1100cb6b5e4fa2b293a 129 PRINTS PR00421 Thioredoxin family signature 32 40 3.9E-5 T 29-03-2018 THSYN_RS25795 cbcded3da16ff1100cb6b5e4fa2b293a 129 PRINTS PR00421 Thioredoxin family signature 40 49 3.9E-5 T 29-03-2018 THSYN_RS25795 cbcded3da16ff1100cb6b5e4fa2b293a 129 Pfam PF00085 Thioredoxin 14 114 2.0E-19 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 THSYN_RS25795 cbcded3da16ff1100cb6b5e4fa2b293a 129 Gene3D G3DSA:3.40.30.10 3 127 2.8E-24 T 29-03-2018 THSYN_RS17910 63485e8920626afe06ef36367b3a3d90 425 SUPERFAMILY SSF52540 63 398 1.5E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17910 63485e8920626afe06ef36367b3a3d90 425 SMART SM01086 317 411 6.9E-34 T 29-03-2018 IPR019489 Clp ATPase, C-terminal THSYN_RS17910 63485e8920626afe06ef36367b3a3d90 425 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 310 1.2E-48 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS17910 63485e8920626afe06ef36367b3a3d90 425 Pfam PF06689 ClpX C4-type zinc finger 15 52 2.1E-20 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 THSYN_RS17910 63485e8920626afe06ef36367b3a3d90 425 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 13 412 9.7E-202 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 THSYN_RS17910 63485e8920626afe06ef36367b3a3d90 425 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 392 1.2E-17 T 29-03-2018 IPR019489 Clp ATPase, C-terminal THSYN_RS17910 63485e8920626afe06ef36367b3a3d90 425 SMART SM00382 112 333 8.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS17910 63485e8920626afe06ef36367b3a3d90 425 SUPERFAMILY SSF57716 15 50 7.41E-12 T 29-03-2018 THSYN_RS17910 63485e8920626afe06ef36367b3a3d90 425 SMART SM00994 14 53 1.8E-24 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 THSYN_RS17910 63485e8920626afe06ef36367b3a3d90 425 Gene3D G3DSA:3.40.50.300 57 315 4.1E-71 T 29-03-2018 THSYN_RS17910 63485e8920626afe06ef36367b3a3d90 425 Gene3D G3DSA:1.10.8.60 317 408 1.9E-32 T 29-03-2018 THSYN_RS17910 63485e8920626afe06ef36367b3a3d90 425 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 7 415 52.793 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 THSYN_RS22225 937370b73943ec4aae11d356c68e64ec 123 Gene3D G3DSA:1.10.3830.10 8 120 5.5E-40 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 THSYN_RS22225 937370b73943ec4aae11d356c68e64ec 123 Pfam PF01219 Prokaryotic diacylglycerol kinase 18 118 2.8E-34 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 THSYN_RS22225 937370b73943ec4aae11d356c68e64ec 123 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 71 82 - T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 THSYN_RS03885 e25127fb41a6c98834d4eef311990e1b 126 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 10 112 2.1E-22 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 THSYN_RS03885 e25127fb41a6c98834d4eef311990e1b 126 Pfam PF01521 Iron-sulphur cluster biosynthesis 9 99 5.2E-11 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS03885 e25127fb41a6c98834d4eef311990e1b 126 Gene3D G3DSA:2.60.300.12 9 117 2.6E-23 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS03885 e25127fb41a6c98834d4eef311990e1b 126 SUPERFAMILY SSF89360 7 101 2.75E-21 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS21515 84cf73815b50988e117f4d5557d6421b 700 SUPERFAMILY SSF56601 222 653 3.22E-89 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS21515 84cf73815b50988e117f4d5557d6421b 700 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 234 632 1.4E-60 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS21515 84cf73815b50988e117f4d5557d6421b 700 Gene3D G3DSA:3.40.710.10 208 657 4.7E-35 T 29-03-2018 THSYN_RS21515 84cf73815b50988e117f4d5557d6421b 700 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 532 546 1.5E-19 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS21515 84cf73815b50988e117f4d5557d6421b 700 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 474 496 1.5E-19 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS21515 84cf73815b50988e117f4d5557d6421b 700 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 609 622 1.5E-19 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS21515 84cf73815b50988e117f4d5557d6421b 700 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 246 265 1.5E-19 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS21515 84cf73815b50988e117f4d5557d6421b 700 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 547 561 1.5E-19 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS21515 84cf73815b50988e117f4d5557d6421b 700 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 209 650 1.4E-84 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS03610 50ba4c8ffcf7713fa6b57db7ca6feb9c 84 Pfam PF04226 Transglycosylase associated protein 37 83 1.0E-6 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 THSYN_RS14890 ee8ddc5b4bb8549cd90e36135fb332d0 202 Pfam PF12263 Protein of unknown function (DUF3611) 13 190 4.8E-35 T 29-03-2018 IPR022051 Protein of unknown function DUF3611 THSYN_RS07285 7619ddd03595fe0e39d15ba87de9c89b 282 Pfam PF05685 Putative restriction endonuclease 37 207 1.6E-15 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS07285 7619ddd03595fe0e39d15ba87de9c89b 282 SUPERFAMILY SSF52980 26 210 4.93E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS07285 7619ddd03595fe0e39d15ba87de9c89b 282 Gene3D G3DSA:3.90.1570.10 23 213 4.3E-21 T 29-03-2018 THSYN_RS21690 5718dcf27e7e428ef16c8455afd2b6aa 142 Pfam PF01850 PIN domain 5 122 2.1E-6 T 29-03-2018 IPR002716 PIN domain THSYN_RS21690 5718dcf27e7e428ef16c8455afd2b6aa 142 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 134 9.597 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS21690 5718dcf27e7e428ef16c8455afd2b6aa 142 Gene3D G3DSA:3.40.50.1010 3 134 3.9E-12 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS21690 5718dcf27e7e428ef16c8455afd2b6aa 142 SUPERFAMILY SSF88723 1 130 3.08E-17 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS14665 b920e46c3f7d08d897bdd7703288ccba 325 SUPERFAMILY SSF82171 57 318 3.53E-37 T 29-03-2018 THSYN_RS14665 b920e46c3f7d08d897bdd7703288ccba 325 Gene3D G3DSA:2.140.10.30 157 325 1.9E-23 T 29-03-2018 THSYN_RS14665 b920e46c3f7d08d897bdd7703288ccba 325 Gene3D G3DSA:2.140.10.30 49 156 9.5E-13 T 29-03-2018 THSYN_RS14665 b920e46c3f7d08d897bdd7703288ccba 325 Pfam PF07676 WD40-like Beta Propeller Repeat 80 108 0.0022 T 29-03-2018 IPR011659 WD40-like Beta Propeller THSYN_RS14665 b920e46c3f7d08d897bdd7703288ccba 325 Pfam PF07676 WD40-like Beta Propeller Repeat 220 247 0.022 T 29-03-2018 IPR011659 WD40-like Beta Propeller THSYN_RS14665 b920e46c3f7d08d897bdd7703288ccba 325 Pfam PF07676 WD40-like Beta Propeller Repeat 267 298 2.6E-6 T 29-03-2018 IPR011659 WD40-like Beta Propeller THSYN_RS14665 b920e46c3f7d08d897bdd7703288ccba 325 Pfam PF07676 WD40-like Beta Propeller Repeat 173 192 2.1E-4 T 29-03-2018 IPR011659 WD40-like Beta Propeller THSYN_RS22795 2c897610223254aeb31bf9658e65a875 387 Gene3D G3DSA:3.40.50.2000 211 379 1.8E-33 T 29-03-2018 THSYN_RS22795 2c897610223254aeb31bf9658e65a875 387 SUPERFAMILY SSF53756 26 386 1.05E-62 T 29-03-2018 THSYN_RS22795 2c897610223254aeb31bf9658e65a875 387 Pfam PF13439 Glycosyltransferase Family 4 31 187 1.0E-17 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS22795 2c897610223254aeb31bf9658e65a875 387 Pfam PF00534 Glycosyl transferases group 1 199 366 9.9E-26 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS22795 2c897610223254aeb31bf9658e65a875 387 Gene3D G3DSA:3.40.50.2000 16 210 1.5E-12 T 29-03-2018 THSYN_RS14320 1ef98334e1c11ce33dacd48f29853655 363 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 17 344 4.1E-112 T 29-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 THSYN_RS14320 1ef98334e1c11ce33dacd48f29853655 363 Pfam PF01758 Sodium Bile acid symporter family 63 257 8.6E-33 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 THSYN_RS14320 1ef98334e1c11ce33dacd48f29853655 363 PIRSF PIRSF005508 4 361 1.2E-115 T 29-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 THSYN_RS17070 49b46d12eb8cc441890c25943817c026 487 Pfam PF01943 Polysaccharide biosynthesis protein 2 260 4.6E-19 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 THSYN_RS05335 81d0425fd7df67399cec912f6cdde2af 846 Gene3D G3DSA:3.40.50.410 268 425 1.3E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS05335 81d0425fd7df67399cec912f6cdde2af 846 SMART SM00327 266 437 4.6E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS05335 81d0425fd7df67399cec912f6cdde2af 846 SUPERFAMILY SSF53300 269 423 1.71E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS05335 81d0425fd7df67399cec912f6cdde2af 846 Pfam PF08487 Vault protein inter-alpha-trypsin domain 26 129 4.7E-19 T 29-03-2018 IPR013694 VIT domain THSYN_RS05335 81d0425fd7df67399cec912f6cdde2af 846 SMART SM00609 19 131 0.002 T 29-03-2018 IPR013694 VIT domain THSYN_RS05335 81d0425fd7df67399cec912f6cdde2af 846 Pfam PF13768 von Willebrand factor type A domain 271 417 5.5E-16 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS22460 bd178b74bd273eb1acf27f2b439a9d50 185 Pfam PF05685 Putative restriction endonuclease 33 171 2.9E-18 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS22460 bd178b74bd273eb1acf27f2b439a9d50 185 SUPERFAMILY SSF52980 33 161 3.0E-11 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS22460 bd178b74bd273eb1acf27f2b439a9d50 185 Gene3D G3DSA:3.90.1570.10 8 185 2.1E-21 T 29-03-2018 THSYN_RS19170 d6b8018989908fbecd9e7e9e239cd6b7 291 Pfam PF14261 Domain of unknown function (DUF4351) 231 284 1.0E-7 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS19170 d6b8018989908fbecd9e7e9e239cd6b7 291 Pfam PF11103 Protein of unknown function (DUF2887) 3 201 1.4E-34 T 29-03-2018 IPR022573 Protein of unknown function DUF2887 THSYN_RS10330 d9750a0ebf15b6baaa86dcaa8f5a1605 145 SUPERFAMILY SSF55021 2 68 7.05E-12 T 29-03-2018 THSYN_RS10330 d9750a0ebf15b6baaa86dcaa8f5a1605 145 Pfam PF01842 ACT domain 72 122 2.0E-6 T 29-03-2018 IPR002912 ACT domain THSYN_RS10330 d9750a0ebf15b6baaa86dcaa8f5a1605 145 SUPERFAMILY SSF55021 72 140 1.37E-13 T 29-03-2018 THSYN_RS10330 d9750a0ebf15b6baaa86dcaa8f5a1605 145 Gene3D G3DSA:3.30.2130.10 71 143 6.0E-9 T 29-03-2018 THSYN_RS10330 d9750a0ebf15b6baaa86dcaa8f5a1605 145 Gene3D G3DSA:3.30.2130.10 2 70 2.6E-5 T 29-03-2018 THSYN_RS15825 514416af8ab495c3b2d12a7a48bbc859 535 Pfam PF10081 Alpha/beta-hydrolase family 243 530 2.8E-115 T 29-03-2018 IPR027787 Alpha/beta-hydrolase, catalytic domain THSYN_RS15825 514416af8ab495c3b2d12a7a48bbc859 535 Pfam PF15420 Alpha/beta-hydrolase family N-terminus 19 226 1.2E-68 T 29-03-2018 IPR027788 Alpha/beta-hydrolase, N-terminal domain THSYN_RS15825 514416af8ab495c3b2d12a7a48bbc859 535 PIRSF PIRSF007542 3 535 6.5E-223 T 29-03-2018 IPR012037 Alpha/beta-hydrolase family THSYN_RS09315 99e88dfde569b7df53cf71badedd7737 741 SMART SM00954 256 366 1.3E-62 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 THSYN_RS09315 99e88dfde569b7df53cf71badedd7737 741 SUPERFAMILY SSF81301 213 385 1.8E-61 T 29-03-2018 THSYN_RS09315 99e88dfde569b7df53cf71badedd7737 741 Pfam PF13291 ACT domain 662 739 5.8E-20 T 29-03-2018 IPR002912 ACT domain THSYN_RS09315 99e88dfde569b7df53cf71badedd7737 741 SUPERFAMILY SSF55021 662 739 1.58E-15 T 29-03-2018 THSYN_RS09315 99e88dfde569b7df53cf71badedd7737 741 Gene3D G3DSA:3.30.460.10 213 346 2.6E-43 T 29-03-2018 THSYN_RS09315 99e88dfde569b7df53cf71badedd7737 741 Gene3D G3DSA:3.30.70.260 661 741 6.0E-15 T 29-03-2018 THSYN_RS09315 99e88dfde569b7df53cf71badedd7737 741 SUPERFAMILY SSF109604 20 212 1.98E-42 T 29-03-2018 THSYN_RS09315 99e88dfde569b7df53cf71badedd7737 741 Gene3D G3DSA:3.10.20.30 403 478 4.3E-23 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS09315 99e88dfde569b7df53cf71badedd7737 741 SUPERFAMILY SSF81271 400 468 4.58E-20 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THSYN_RS09315 99e88dfde569b7df53cf71badedd7737 741 Pfam PF04607 Region found in RelA / SpoT proteins 256 366 1.0E-34 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 THSYN_RS09315 99e88dfde569b7df53cf71badedd7737 741 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 55 739 3.7E-188 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 THSYN_RS09315 99e88dfde569b7df53cf71badedd7737 741 Pfam PF13328 HD domain 41 197 7.6E-41 T 29-03-2018 IPR003607 HD/PDEase domain THSYN_RS09315 99e88dfde569b7df53cf71badedd7737 741 Pfam PF02824 TGS domain 409 468 3.5E-21 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 THSYN_RS21740 cd4d80035fd15d8987b3b3ab917985fb 1085 SUPERFAMILY SSF48452 893 996 2.78E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS21740 cd4d80035fd15d8987b3b3ab917985fb 1085 Gene3D G3DSA:1.25.40.10 401 785 1.8E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS21740 cd4d80035fd15d8987b3b3ab917985fb 1085 Pfam PF13176 Tetratricopeptide repeat 706 732 0.0014 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS21740 cd4d80035fd15d8987b3b3ab917985fb 1085 SUPERFAMILY SSF52540 100 289 1.9E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21740 cd4d80035fd15d8987b3b3ab917985fb 1085 SUPERFAMILY SSF48452 690 773 4.67E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS21740 cd4d80035fd15d8987b3b3ab917985fb 1085 Pfam PF13191 AAA ATPase domain 101 236 6.8E-9 T 29-03-2018 THSYN_RS21740 cd4d80035fd15d8987b3b3ab917985fb 1085 Gene3D G3DSA:1.10.150.200 926 1082 9.7E-7 T 29-03-2018 THSYN_RS21740 cd4d80035fd15d8987b3b3ab917985fb 1085 Gene3D G3DSA:1.25.40.10 859 925 0.0086 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS21740 cd4d80035fd15d8987b3b3ab917985fb 1085 SMART SM00028 892 926 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS21740 cd4d80035fd15d8987b3b3ab917985fb 1085 SMART SM00028 704 737 5.4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS21740 cd4d80035fd15d8987b3b3ab917985fb 1085 SMART SM00028 931 964 12.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS21740 cd4d80035fd15d8987b3b3ab917985fb 1085 Gene3D G3DSA:3.40.50.300 83 292 3.0E-10 T 29-03-2018 THSYN_RS15780 c80bdbbf597f75b0440fff9d3b736240 388 SMART SM00244 85 246 2.3E-30 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS15780 c80bdbbf597f75b0440fff9d3b736240 388 Pfam PF01145 SPFH domain / Band 7 family 89 261 2.4E-24 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS15780 c80bdbbf597f75b0440fff9d3b736240 388 Pfam PF12221 Bacterial membrane protein N terminal 1 45 2.9E-17 T 29-03-2018 IPR020980 Menbrane protein HflK, N-terminal THSYN_RS15780 c80bdbbf597f75b0440fff9d3b736240 388 PRINTS PR00721 Stomatin signature 92 114 4.4E-6 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS15780 c80bdbbf597f75b0440fff9d3b736240 388 PRINTS PR00721 Stomatin signature 140 161 4.4E-6 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS15780 c80bdbbf597f75b0440fff9d3b736240 388 PRINTS PR00721 Stomatin signature 222 240 4.4E-6 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS15780 c80bdbbf597f75b0440fff9d3b736240 388 TIGRFAM TIGR01933 hflK: HflK protein 87 348 3.2E-98 T 29-03-2018 IPR010201 HflK GO:0016021 THSYN_RS15780 c80bdbbf597f75b0440fff9d3b736240 388 SUPERFAMILY SSF117892 120 252 1.31E-20 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS26655 264a6a6ca05c2e78647f6a4226cec142 221 Pfam PF03567 Sulfotransferase family 6 215 2.1E-11 T 29-03-2018 IPR005331 Sulfotransferase GO:0008146|GO:0016021 THSYN_RS26655 264a6a6ca05c2e78647f6a4226cec142 221 Gene3D G3DSA:3.40.50.300 4 220 2.2E-7 T 29-03-2018 THSYN_RS26655 264a6a6ca05c2e78647f6a4226cec142 221 SUPERFAMILY SSF52540 7 218 1.68E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS01585 f8d5954dcc090e8266853a8384778ba0 76 Gene3D G3DSA:2.10.260.10 1 76 3.9E-8 T 29-03-2018 THSYN_RS01585 f8d5954dcc090e8266853a8384778ba0 76 SUPERFAMILY SSF89447 2 58 6.28E-6 T 29-03-2018 THSYN_RS07355 47b486852341d53e2a503755bb3c648f 95 Gene3D G3DSA:3.40.50.150 2 93 1.3E-7 T 29-03-2018 THSYN_RS07355 47b486852341d53e2a503755bb3c648f 95 Pfam PF01555 DNA methylase 4 39 6.9E-8 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THSYN_RS07355 47b486852341d53e2a503755bb3c648f 95 SUPERFAMILY SSF53335 4 39 4.76E-7 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS05960 ca04f87932fe8817b5098e4d34753328 190 SUPERFAMILY SSF51182 1 180 2.05E-75 T 29-03-2018 IPR011051 RmlC-like cupin domain THSYN_RS05960 ca04f87932fe8817b5098e4d34753328 190 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 179 4.0E-63 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THSYN_RS05960 ca04f87932fe8817b5098e4d34753328 190 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 177 3.5E-73 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THSYN_RS05960 ca04f87932fe8817b5098e4d34753328 190 Gene3D G3DSA:2.60.120.10 1 185 9.8E-73 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS05960 ca04f87932fe8817b5098e4d34753328 190 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 177 6.0E-72 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THSYN_RS19960 6114bfa9feabbb2772f5430fa2b24a72 405 Gene3D G3DSA:3.30.200.20 133 205 0.0013 T 29-03-2018 THSYN_RS19960 6114bfa9feabbb2772f5430fa2b24a72 405 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 5 106 9.9E-14 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 THSYN_RS19960 6114bfa9feabbb2772f5430fa2b24a72 405 Pfam PF07804 HipA-like C-terminal domain 134 372 4.8E-53 T 29-03-2018 IPR012893 HipA-like, C-terminal THSYN_RS19960 6114bfa9feabbb2772f5430fa2b24a72 405 Pfam PF13657 HipA N-terminal domain 5 105 3.6E-19 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 THSYN_RS20710 e3d1d33affd030a2ac9587ff3f291725 298 Pfam PF00696 Amino acid kinase family 28 274 8.6E-46 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase THSYN_RS20710 e3d1d33affd030a2ac9587ff3f291725 298 PRINTS PR00474 Glutamate 5-kinase family signature 197 224 5.5E-10 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THSYN_RS20710 e3d1d33affd030a2ac9587ff3f291725 298 PRINTS PR00474 Glutamate 5-kinase family signature 59 73 5.5E-10 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THSYN_RS20710 e3d1d33affd030a2ac9587ff3f291725 298 PRINTS PR00474 Glutamate 5-kinase family signature 247 267 5.5E-10 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THSYN_RS20710 e3d1d33affd030a2ac9587ff3f291725 298 Hamap MF_00082_B Acetylglutamate kinase [argB]. 26 297 36.94 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THSYN_RS20710 e3d1d33affd030a2ac9587ff3f291725 298 Gene3D G3DSA:3.40.1160.10 3 298 1.8E-75 T 29-03-2018 THSYN_RS20710 e3d1d33affd030a2ac9587ff3f291725 298 PIRSF PIRSF000728 13 297 4.8E-106 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THSYN_RS20710 e3d1d33affd030a2ac9587ff3f291725 298 SUPERFAMILY SSF53633 8 297 2.75E-96 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase THSYN_RS20710 e3d1d33affd030a2ac9587ff3f291725 298 Hamap MF_00082_A Acetylglutamate kinase [argB]. 29 282 29.596 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THSYN_RS20710 e3d1d33affd030a2ac9587ff3f291725 298 TIGRFAM TIGR00761 argB: acetylglutamate kinase 29 272 5.5E-77 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THSYN_RS12645 2eb09f9543f115a095ce9696df971f45 318 SUPERFAMILY SSF53850 38 268 1.16E-31 T 29-03-2018 THSYN_RS12645 2eb09f9543f115a095ce9696df971f45 318 Pfam PF09084 NMT1/THI5 like 53 257 5.8E-18 T 29-03-2018 IPR015168 SsuA/THI5-like THSYN_RS12645 2eb09f9543f115a095ce9696df971f45 318 Gene3D G3DSA:3.40.190.10 34 127 4.3E-5 T 29-03-2018 THSYN_RS12645 2eb09f9543f115a095ce9696df971f45 318 Gene3D G3DSA:3.40.190.10 128 257 1.9E-22 T 29-03-2018 THSYN_RS09335 7fb6b41cd36473f23b58a46111bd3949 413 Pfam PF06245 Protein of unknown function (DUF1015) 4 411 4.3E-128 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 THSYN_RS09335 7fb6b41cd36473f23b58a46111bd3949 413 PIRSF PIRSF033563 1 413 3.0E-126 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 THSYN_RS09335 7fb6b41cd36473f23b58a46111bd3949 413 Gene3D G3DSA:1.10.10.10 56 114 0.091 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS16540 b4459f3332dae9e863be833e564d4d88 213 Gene3D G3DSA:3.30.70.20 20 47 0.11 T 29-03-2018 THSYN_RS16540 b4459f3332dae9e863be833e564d4d88 213 Gene3D G3DSA:3.30.70.20 48 90 1.2E-8 T 29-03-2018 THSYN_RS16540 b4459f3332dae9e863be833e564d4d88 213 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS16540 b4459f3332dae9e863be833e564d4d88 213 Pfam PF13183 4Fe-4S dicluster domain 37 96 4.3E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS16540 b4459f3332dae9e863be833e564d4d88 213 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 39 50 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS16540 b4459f3332dae9e863be833e564d4d88 213 Gene3D G3DSA:3.30.70.20 91 138 0.32 T 29-03-2018 THSYN_RS16540 b4459f3332dae9e863be833e564d4d88 213 SUPERFAMILY SSF46548 37 118 6.28E-14 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS25275 be095e3d25f90b9e54c16a816e511492 260 SUPERFAMILY SSF55811 100 229 1.62E-25 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 THSYN_RS25275 be095e3d25f90b9e54c16a816e511492 260 Pfam PF00293 NUDIX domain 113 224 1.3E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THSYN_RS25275 be095e3d25f90b9e54c16a816e511492 260 Gene3D G3DSA:3.90.79.10 96 244 2.1E-22 T 29-03-2018 THSYN_RS29705 d13c1a7f37b8ff919e00b6a4736072ad 471 Hamap MF_01338 Ribulose bisphosphate carboxylase large chain [rbcL]. 2 468 58.492 T 29-03-2018 IPR020888 Ribulose bisphosphate carboxylase large subunit, type I GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS29705 d13c1a7f37b8ff919e00b6a4736072ad 471 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 17 137 2.0E-41 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS29705 d13c1a7f37b8ff919e00b6a4736072ad 471 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 147 455 3.8E-130 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS29705 d13c1a7f37b8ff919e00b6a4736072ad 471 SUPERFAMILY SSF51649 142 466 1.28E-139 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS29705 d13c1a7f37b8ff919e00b6a4736072ad 471 Gene3D G3DSA:3.20.20.110 143 456 2.0E-149 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS29705 d13c1a7f37b8ff919e00b6a4736072ad 471 SUPERFAMILY SSF54966 5 141 7.33E-53 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS29705 d13c1a7f37b8ff919e00b6a4736072ad 471 Gene3D G3DSA:3.30.70.150 17 140 2.1E-42 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS11665 6b7802800abf7826588f234442112406 630 Pfam PF01964 Radical SAM ThiC family 139 590 4.0E-193 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THSYN_RS11665 6b7802800abf7826588f234442112406 630 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 138 596 54.899 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THSYN_RS11665 6b7802800abf7826588f234442112406 630 Pfam PF13667 ThiC-associated domain 22 99 1.8E-32 T 29-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THSYN_RS11665 6b7802800abf7826588f234442112406 630 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 138 594 3.1E-208 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THSYN_RS08215 99182ebb258111630c71c0d6652ca483 167 Pfam PF06897 Protein of unknown function (DUF1269) 60 160 1.6E-36 T 29-03-2018 IPR009200 Protein of unknown function DUF1269, membrane associated THSYN_RS05620 538a6b53f32644bf43f1fc59701ff4b2 1410 Pfam PF13116 Protein of unknown function 594 874 8.8E-51 T 29-03-2018 IPR025263 Domain of unknown function DUF3971 THSYN_RS05620 538a6b53f32644bf43f1fc59701ff4b2 1410 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 40 1367 1.7E-205 T 29-03-2018 IPR011836 Conserved hypothetical protein CHP02099 THSYN_RS05620 538a6b53f32644bf43f1fc59701ff4b2 1410 Pfam PF13502 AsmA-like C-terminal region 1120 1362 5.1E-44 T 29-03-2018 IPR032712 AsmA-like, C-terminal THSYN_RS26105 2745204a8222892e072a8a0927573739 180 SUPERFAMILY SSF143422 1 137 4.45E-35 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS26105 2745204a8222892e072a8a0927573739 180 Gene3D G3DSA:3.30.70.1290 1 137 6.6E-33 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS26105 2745204a8222892e072a8a0927573739 180 Pfam PF01797 Transposase IS200 like 13 130 2.8E-10 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS26105 2745204a8222892e072a8a0927573739 180 SMART SM01321 9 131 1.9E-37 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS02520 be0463641b1d00c1cbcb9d319c6324e1 137 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 28 1.6E-4 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS02520 be0463641b1d00c1cbcb9d319c6324e1 137 Pfam PF07963 Prokaryotic N-terminal methylation motif 3 29 6.1E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS02520 be0463641b1d00c1cbcb9d319c6324e1 137 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 7 27 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS08980 083ce0deaaca82f66dec3d8ef18e0f52 194 SUPERFAMILY SSF52980 2 183 1.02E-20 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS08980 083ce0deaaca82f66dec3d8ef18e0f52 194 Gene3D G3DSA:3.90.1570.10 2 189 6.3E-39 T 29-03-2018 THSYN_RS08980 083ce0deaaca82f66dec3d8ef18e0f52 194 Pfam PF05685 Putative restriction endonuclease 15 168 3.2E-27 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS21490 3481dcedf2c74a502ab04cc07c8d4ed4 1545 SUPERFAMILY SSF52540 28 204 9.29E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21490 3481dcedf2c74a502ab04cc07c8d4ed4 1545 SUPERFAMILY SSF52540 261 403 9.29E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21490 3481dcedf2c74a502ab04cc07c8d4ed4 1545 SMART SM00487 15 231 4.3E-36 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS21490 3481dcedf2c74a502ab04cc07c8d4ed4 1545 Gene3D G3DSA:1.10.10.10 1038 1103 0.035 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS21490 3481dcedf2c74a502ab04cc07c8d4ed4 1545 Gene3D G3DSA:3.40.50.300 6 211 3.6E-37 T 29-03-2018 THSYN_RS21490 3481dcedf2c74a502ab04cc07c8d4ed4 1545 SMART SM00490 304 399 3.0E-12 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS21490 3481dcedf2c74a502ab04cc07c8d4ed4 1545 Pfam PF00270 DEAD/DEAH box helicase 20 202 1.9E-27 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS21490 3481dcedf2c74a502ab04cc07c8d4ed4 1545 Pfam PF00271 Helicase conserved C-terminal domain 288 399 1.9E-10 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS21490 3481dcedf2c74a502ab04cc07c8d4ed4 1545 Pfam PF08494 DEAD/H associated 659 846 4.3E-65 T 29-03-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 THSYN_RS21490 3481dcedf2c74a502ab04cc07c8d4ed4 1545 Gene3D G3DSA:3.40.50.300 267 411 1.1E-24 T 29-03-2018 THSYN_RS19585 460aecd977f3eee3da754ea822b30c99 105 Gene3D G3DSA:3.30.300.90 1 91 5.7E-27 T 29-03-2018 THSYN_RS19585 460aecd977f3eee3da754ea822b30c99 105 SUPERFAMILY SSF82657 3 88 6.15E-28 T 29-03-2018 IPR002634 BolA protein THSYN_RS19585 460aecd977f3eee3da754ea822b30c99 105 Pfam PF01722 BolA-like protein 11 84 8.7E-29 T 29-03-2018 IPR002634 BolA protein THSYN_RS19585 460aecd977f3eee3da754ea822b30c99 105 PIRSF PIRSF003113 1 100 6.4E-32 T 29-03-2018 IPR002634 BolA protein THSYN_RS11130 bcdf8739ce2de7601c30ad8b18313a94 201 Gene3D G3DSA:3.40.1800.10 79 155 1.6E-17 T 29-03-2018 THSYN_RS11130 bcdf8739ce2de7601c30ad8b18313a94 201 Pfam PF14279 HNH endonuclease 99 153 2.1E-16 T 29-03-2018 IPR029471 HNH endonuclease 5 THSYN_RS11130 bcdf8739ce2de7601c30ad8b18313a94 201 SMART SM00507 86 139 3.4E-11 T 29-03-2018 IPR003615 HNH nuclease THSYN_RS29620 1dd7653a914f2737ef9045bc29c44f1e 161 SUPERFAMILY SSF48657 1 34 1.44E-6 T 29-03-2018 IPR016103 ProQ/FinO domain THSYN_RS29620 1dd7653a914f2737ef9045bc29c44f1e 161 Pfam PF04352 ProQ/FINO family 1 34 5.0E-5 T 29-03-2018 IPR016103 ProQ/FinO domain THSYN_RS29620 1dd7653a914f2737ef9045bc29c44f1e 161 Gene3D G3DSA:1.10.1710.10 1 37 7.2E-7 T 29-03-2018 IPR016103 ProQ/FinO domain THSYN_RS12290 62a6e78978077075bc68f69952f82d71 242 Pfam PF13649 Methyltransferase domain 29 123 8.4E-16 T 29-03-2018 THSYN_RS12290 62a6e78978077075bc68f69952f82d71 242 Gene3D G3DSA:3.40.50.150 10 217 6.1E-26 T 29-03-2018 THSYN_RS12290 62a6e78978077075bc68f69952f82d71 242 SUPERFAMILY SSF53335 7 162 5.37E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS16155 856f4364c2bdce5270c188bca4f1cfb6 257 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 191 207 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THSYN_RS16155 856f4364c2bdce5270c188bca4f1cfb6 257 Pfam PF01026 TatD related DNase 3 255 5.0E-71 T 29-03-2018 IPR001130 TatD family GO:0016788 THSYN_RS16155 856f4364c2bdce5270c188bca4f1cfb6 257 PIRSF PIRSF005902 1 257 4.0E-72 T 29-03-2018 IPR001130 TatD family GO:0016788 THSYN_RS16155 856f4364c2bdce5270c188bca4f1cfb6 257 Gene3D G3DSA:3.20.20.140 1 257 4.9E-78 T 29-03-2018 THSYN_RS16155 856f4364c2bdce5270c188bca4f1cfb6 257 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 126 136 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THSYN_RS16155 856f4364c2bdce5270c188bca4f1cfb6 257 SUPERFAMILY SSF51556 1 256 8.94E-83 T 29-03-2018 IPR032466 Metal-dependent hydrolase THSYN_RS16155 856f4364c2bdce5270c188bca4f1cfb6 257 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 3 255 6.7E-77 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 THSYN_RS15640 d23c867f5e57fbfdabe9d702c230be1c 343 SMART SM00244 21 252 1.0E-7 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS15640 d23c867f5e57fbfdabe9d702c230be1c 343 Pfam PF01145 SPFH domain / Band 7 family 25 269 3.9E-20 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS15640 d23c867f5e57fbfdabe9d702c230be1c 343 SUPERFAMILY SSF117892 78 160 9.29E-8 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS16750 4b1be636739cca740a04bd4fda982e82 102 Gene3D G3DSA:1.20.120.330 1 100 6.4E-15 T 29-03-2018 THSYN_RS16750 4b1be636739cca740a04bd4fda982e82 102 Pfam PF05168 HEPN domain 7 85 2.3E-8 T 29-03-2018 IPR007842 HEPN domain THSYN_RS31485 aab904ff3a19e8d6da7a4bcf71aa8480 164 Gene3D G3DSA:3.20.20.80 29 160 1.1E-16 T 29-03-2018 THSYN_RS31485 aab904ff3a19e8d6da7a4bcf71aa8480 164 SUPERFAMILY SSF51445 34 160 1.17E-16 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS31485 aab904ff3a19e8d6da7a4bcf71aa8480 164 Pfam PF03198 Glucanosyltransferase 33 160 1.0E-29 T 29-03-2018 IPR004886 Glucanosyltransferase THSYN_RS05600 fe060a47603e9cace21a16a2a12dc98f 442 SUPERFAMILY SSF116734 2 206 2.94E-36 T 29-03-2018 THSYN_RS05600 fe060a47603e9cace21a16a2a12dc98f 442 Pfam PF01420 Type I restriction modification DNA specificity domain 73 192 1.4E-18 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS05600 fe060a47603e9cace21a16a2a12dc98f 442 SUPERFAMILY SSF116734 236 435 1.37E-13 T 29-03-2018 THSYN_RS05600 fe060a47603e9cace21a16a2a12dc98f 442 Gene3D G3DSA:3.90.220.20 1 185 2.0E-27 T 29-03-2018 THSYN_RS05600 fe060a47603e9cace21a16a2a12dc98f 442 Gene3D G3DSA:3.90.220.20 186 409 1.4E-13 T 29-03-2018 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 670 9.5E-31 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 697 715 9.5E-31 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 726 744 9.5E-31 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 759 773 9.5E-31 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 Gene3D G3DSA:1.10.8.60 377 598 1.8E-39 T 29-03-2018 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 13 903 0.0 T 29-03-2018 IPR017729 Type VI secretion system, ATPase ClpV1 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 Gene3D G3DSA:3.40.50.300 614 819 9.7E-29 T 29-03-2018 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 Gene3D G3DSA:1.10.8.60 820 915 2.0E-12 T 29-03-2018 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 236 368 6.3E-9 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 Gene3D G3DSA:1.10.1780.10 1 163 4.4E-21 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 820 894 1.8E-13 T 29-03-2018 IPR019489 Clp ATPase, C-terminal THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 SUPERFAMILY SSF81923 12 132 1.43E-17 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 Pfam PF07724 AAA domain (Cdc48 subfamily) 647 813 1.2E-35 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 SUPERFAMILY SSF52540 192 521 6.99E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 327 339 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 SMART SM00382 231 376 1.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 SMART SM00382 648 790 1.3E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 SUPERFAMILY SSF52540 597 894 1.14E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 Gene3D G3DSA:3.40.50.300 190 375 1.1E-23 T 29-03-2018 THSYN_RS32855 8d621a5068137920efef2ec84a8b3b02 916 SMART SM01086 820 910 9.1E-12 T 29-03-2018 IPR019489 Clp ATPase, C-terminal THSYN_RS01725 c6bd61ae8dfd53758664d9d7079213ba 577 Gene3D G3DSA:3.40.50.1460 1 254 9.4E-20 T 29-03-2018 THSYN_RS01725 c6bd61ae8dfd53758664d9d7079213ba 577 SUPERFAMILY SSF52129 4 200 5.75E-11 T 29-03-2018 IPR029030 Caspase-like domain THSYN_RS01725 c6bd61ae8dfd53758664d9d7079213ba 577 Pfam PF00656 Caspase domain 3 127 2.5E-6 T 29-03-2018 THSYN_RS03530 a22aac5569da9c980ecb27d3656759dd 583 Pfam PF03717 Penicillin-binding Protein dimerisation domain 67 220 1.9E-14 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 THSYN_RS03530 a22aac5569da9c980ecb27d3656759dd 583 SUPERFAMILY SSF56519 65 234 1.96E-41 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 THSYN_RS03530 a22aac5569da9c980ecb27d3656759dd 583 SUPERFAMILY SSF56601 186 573 2.65E-95 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS03530 a22aac5569da9c980ecb27d3656759dd 583 Gene3D G3DSA:3.40.710.10 236 577 1.4E-90 T 29-03-2018 THSYN_RS03530 a22aac5569da9c980ecb27d3656759dd 583 Gene3D G3DSA:3.90.1310.10 36 235 6.3E-39 T 29-03-2018 THSYN_RS03530 a22aac5569da9c980ecb27d3656759dd 583 Pfam PF00905 Penicillin binding protein transpeptidase domain 260 557 3.8E-75 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THSYN_RS06890 4a2ef3e92ebfae854b6a11d68de2b348 141 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 5 113 6.0E-22 T 29-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like THSYN_RS06890 4a2ef3e92ebfae854b6a11d68de2b348 141 Gene3D G3DSA:3.10.490.10 1 125 8.8E-32 T 29-03-2018 THSYN_RS06890 4a2ef3e92ebfae854b6a11d68de2b348 141 SUPERFAMILY SSF110857 4 114 3.01E-29 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like THSYN_RS31950 5ddab946a31f9cf3e11433d7125c14da 889 SUPERFAMILY SSF55729 680 815 5.38E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS31950 5ddab946a31f9cf3e11433d7125c14da 889 SUPERFAMILY SSF55729 842 865 5.38E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS31950 5ddab946a31f9cf3e11433d7125c14da 889 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 227 319 4.8E-12 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD THSYN_RS31950 5ddab946a31f9cf3e11433d7125c14da 889 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 570 861 3.8E-86 T 29-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal THSYN_RS31950 5ddab946a31f9cf3e11433d7125c14da 889 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 41 318 3.2E-23 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD THSYN_RS31950 5ddab946a31f9cf3e11433d7125c14da 889 Gene3D G3DSA:3.40.630.30 671 854 7.7E-18 T 29-03-2018 THSYN_RS29980 b05f299a3f7428b74a2407fb40b711e0 233 Gene3D G3DSA:1.20.1050.10 88 226 7.3E-8 T 29-03-2018 THSYN_RS29980 b05f299a3f7428b74a2407fb40b711e0 233 SUPERFAMILY SSF52833 1 78 2.49E-9 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS29980 b05f299a3f7428b74a2407fb40b711e0 233 Gene3D G3DSA:3.40.30.10 1 87 1.5E-9 T 29-03-2018 THSYN_RS29980 b05f299a3f7428b74a2407fb40b711e0 233 SUPERFAMILY SSF47616 141 226 6.66E-6 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like THSYN_RS29980 b05f299a3f7428b74a2407fb40b711e0 233 Pfam PF17171 Glutathione S-transferase, C-terminal domain 164 224 7.6E-11 T 29-03-2018 IPR033468 Metaxin, glutathione S-transferase domain THSYN_RS29980 b05f299a3f7428b74a2407fb40b711e0 233 Pfam PF17172 Glutathione S-transferase N-terminal domain 18 112 2.3E-19 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS31085 8501411a466d051c1d7ba342d4990f5b 300 SUPERFAMILY SSF161098 38 292 6.64E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS31085 8501411a466d051c1d7ba342d4990f5b 300 Gene3D G3DSA:1.10.3720.10 19 293 1.0E-33 T 29-03-2018 THSYN_RS31085 8501411a466d051c1d7ba342d4990f5b 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 296 7.2E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS31085 8501411a466d051c1d7ba342d4990f5b 300 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 32 296 4.4E-72 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 THSYN_RS19480 5b7eb05b952d3b79d228423ae98f5dd8 333 SUPERFAMILY SSF56436 109 333 4.71E-65 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS19480 5b7eb05b952d3b79d228423ae98f5dd8 333 Gene3D G3DSA:3.90.1580.10 92 161 3.1E-12 T 29-03-2018 THSYN_RS19480 5b7eb05b952d3b79d228423ae98f5dd8 333 Gene3D G3DSA:3.90.1580.10 162 333 1.0E-48 T 29-03-2018 THSYN_RS19480 5b7eb05b952d3b79d228423ae98f5dd8 333 Pfam PF03781 Sulfatase-modifying factor enzyme 1 108 331 4.8E-46 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS09550 bf98bbe97ec5c8bd64c75ecf15b65069 292 SUPERFAMILY SSF56112 8 284 2.38E-37 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS09550 bf98bbe97ec5c8bd64c75ecf15b65069 292 Gene3D G3DSA:3.30.200.20 1 95 3.4E-23 T 29-03-2018 THSYN_RS09550 bf98bbe97ec5c8bd64c75ecf15b65069 292 Gene3D G3DSA:3.90.1200.10 100 270 1.2E-17 T 29-03-2018 THSYN_RS09550 bf98bbe97ec5c8bd64c75ecf15b65069 292 Pfam PF03881 Fructosamine kinase 4 289 3.2E-96 T 29-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 THSYN_RS09550 bf98bbe97ec5c8bd64c75ecf15b65069 292 PIRSF PIRSF006221 4 292 3.1E-89 T 29-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 THSYN_RS24585 f1b006573738d1a4fb1d09d1581c383f 668 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 170 191 1.3E-50 T 29-03-2018 THSYN_RS24585 f1b006573738d1a4fb1d09d1581c383f 668 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 266 292 1.3E-50 T 29-03-2018 THSYN_RS24585 f1b006573738d1a4fb1d09d1581c383f 668 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 439 458 1.3E-50 T 29-03-2018 THSYN_RS24585 f1b006573738d1a4fb1d09d1581c383f 668 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 83 108 1.3E-50 T 29-03-2018 THSYN_RS24585 f1b006573738d1a4fb1d09d1581c383f 668 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 244 265 1.3E-50 T 29-03-2018 THSYN_RS24585 f1b006573738d1a4fb1d09d1581c383f 668 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 334 346 1.3E-50 T 29-03-2018 THSYN_RS24585 f1b006573738d1a4fb1d09d1581c383f 668 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 4 665 2.8E-229 T 29-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24585 f1b006573738d1a4fb1d09d1581c383f 668 Pfam PF00361 Proton-conducting membrane transporter 146 427 9.8E-81 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24585 f1b006573738d1a4fb1d09d1581c383f 668 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 284 306 1.3E-11 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THSYN_RS24585 f1b006573738d1a4fb1d09d1581c383f 668 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 59 83 1.3E-11 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THSYN_RS24585 f1b006573738d1a4fb1d09d1581c383f 668 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 438 460 1.3E-11 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THSYN_RS24585 f1b006573738d1a4fb1d09d1581c383f 668 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 85 105 1.3E-11 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THSYN_RS24585 f1b006573738d1a4fb1d09d1581c383f 668 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 65 134 6.3E-24 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS31695 f5cb9e63d4e6551240544d68818eb7fc 423 Hamap MF_00352 Light-independent protochlorophyllide reductase subunit N [bchN]. 12 422 52.669 T 29-03-2018 IPR005970 Light-independent protochlorophyllide reductase, N subunit GO:0015995|GO:0016730|GO:0019685|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31695 f5cb9e63d4e6551240544d68818eb7fc 423 Gene3D G3DSA:3.40.50.1980 25 161 1.0E-21 T 29-03-2018 THSYN_RS31695 f5cb9e63d4e6551240544d68818eb7fc 423 Gene3D G3DSA:3.40.50.1980 162 281 7.7E-12 T 29-03-2018 THSYN_RS31695 f5cb9e63d4e6551240544d68818eb7fc 423 PIRSF PIRSF000162 5 423 8.4E-170 T 29-03-2018 IPR005970 Light-independent protochlorophyllide reductase, N subunit GO:0015995|GO:0016730|GO:0019685|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31695 f5cb9e63d4e6551240544d68818eb7fc 423 Gene3D G3DSA:3.40.50.1980 293 423 1.2E-13 T 29-03-2018 THSYN_RS31695 f5cb9e63d4e6551240544d68818eb7fc 423 TIGRFAM TIGR01279 DPOR_bchN: light-independent protochlorophyllide reductase, N subunit 17 422 8.0E-148 T 29-03-2018 IPR005970 Light-independent protochlorophyllide reductase, N subunit GO:0015995|GO:0016730|GO:0019685|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31695 f5cb9e63d4e6551240544d68818eb7fc 423 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 33 414 2.4E-31 T 29-03-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 THSYN_RS31695 f5cb9e63d4e6551240544d68818eb7fc 423 SUPERFAMILY SSF53807 18 418 1.57E-69 T 29-03-2018 THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 27 1261 1.1E-270 T 29-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 Pfam PF00580 UvrD/REP helicase N-terminal domain 35 462 2.8E-55 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 Gene3D G3DSA:3.40.50.300 9 213 7.6E-24 T 29-03-2018 THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 Gene3D G3DSA:3.40.50.300 258 473 1.2E-24 T 29-03-2018 THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 25 1262 20.676 T 29-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 Gene3D G3DSA:3.40.50.300 474 622 1.6E-10 T 29-03-2018 THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 Pfam PF13361 UvrD-like helicase C-terminal domain 728 869 1.5E-10 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 Gene3D G3DSA:3.90.320.10 948 1269 1.7E-75 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 Gene3D G3DSA:3.40.50.300 671 885 4.1E-25 T 29-03-2018 THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1033 1232 2.7E-6 T 29-03-2018 THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 SUPERFAMILY SSF52980 958 1262 2.36E-71 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 SUPERFAMILY SSF52540 847 873 2.24E-105 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 SUPERFAMILY SSF52540 350 512 2.24E-105 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 SUPERFAMILY SSF52540 560 807 2.24E-105 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 SUPERFAMILY SSF52540 131 212 2.24E-105 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10730 6e0f2018c992b9a61c90071baef6414f 1278 SUPERFAMILY SSF52540 32 91 2.24E-105 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08545 9a532c3c4ad54344843a0bb10c957306 95 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 90 5.9E-20 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS08545 9a532c3c4ad54344843a0bb10c957306 95 Gene3D G3DSA:3.30.2310.20 3 91 6.3E-4 T 29-03-2018 THSYN_RS13605 f7428b32b4c1e17a41bae46a3a736189 84 Gene3D G3DSA:3.40.1620.10 1 82 7.1E-16 T 29-03-2018 THSYN_RS13605 f7428b32b4c1e17a41bae46a3a736189 84 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 45 3.9E-13 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS13605 f7428b32b4c1e17a41bae46a3a736189 84 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 44 3.6E-11 T 29-03-2018 THSYN_RS13605 f7428b32b4c1e17a41bae46a3a736189 84 SUPERFAMILY SSF143120 4 45 3.14E-10 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS06870 55c56d8e0ad06f21a22874fbb566ac0d 187 Pfam PF01184 GPR1/FUN34/yaaH family 3 172 1.6E-33 T 29-03-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 THSYN_RS26905 4611626236b6ac9f156e65604efec21e 106 Gene3D G3DSA:3.30.460.10 8 106 1.7E-14 T 29-03-2018 THSYN_RS26905 4611626236b6ac9f156e65604efec21e 106 SUPERFAMILY SSF81301 11 102 1.4E-14 T 29-03-2018 THSYN_RS26905 4611626236b6ac9f156e65604efec21e 106 Pfam PF01909 Nucleotidyltransferase domain 25 53 2.4E-8 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS17270 6c0d091ccc32a89a3512ac5c3dc1813c 916 SUPERFAMILY SSF56300 28 122 3.49E-25 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS17270 6c0d091ccc32a89a3512ac5c3dc1813c 916 SUPERFAMILY SSF56300 168 332 3.49E-25 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS17270 6c0d091ccc32a89a3512ac5c3dc1813c 916 Gene3D G3DSA:3.40.50.10140 455 583 3.8E-17 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS17270 6c0d091ccc32a89a3512ac5c3dc1813c 916 SUPERFAMILY SSF52200 453 574 1.16E-14 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS17270 6c0d091ccc32a89a3512ac5c3dc1813c 916 Gene3D G3DSA:3.60.21.10 23 454 5.9E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS17270 6c0d091ccc32a89a3512ac5c3dc1813c 916 Pfam PF13676 TIR domain 464 572 2.3E-16 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS17270 6c0d091ccc32a89a3512ac5c3dc1813c 916 Pfam PF00149 Calcineurin-like phosphoesterase 28 274 5.3E-12 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS00240 346dbc15cd91b2ada920f253a4566718 164 Gene3D G3DSA:3.40.50.1010 3 141 3.6E-17 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS00240 346dbc15cd91b2ada920f253a4566718 164 SUPERFAMILY SSF88723 5 128 2.03E-11 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS00240 346dbc15cd91b2ada920f253a4566718 164 Pfam PF01850 PIN domain 5 121 8.4E-9 T 29-03-2018 IPR002716 PIN domain THSYN_RS19055 ad414e11e2caf43d83ca7c0d48660751 546 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 503 4.9E-168 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 THSYN_RS19055 ad414e11e2caf43d83ca7c0d48660751 546 PIRSF PIRSF006446 2 522 1.2E-139 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 THSYN_RS07330 40130d272fcb93e0b0da43b1da8a3acd 288 SUPERFAMILY SSF53335 6 282 1.06E-72 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS07330 40130d272fcb93e0b0da43b1da8a3acd 288 Gene3D G3DSA:2.30.140.10 5 60 1.2E-18 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THSYN_RS07330 40130d272fcb93e0b0da43b1da8a3acd 288 Pfam PF01564 Spermine/spermidine synthase domain 63 241 3.5E-42 T 29-03-2018 THSYN_RS07330 40130d272fcb93e0b0da43b1da8a3acd 288 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 6 283 34.264 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THSYN_RS07330 40130d272fcb93e0b0da43b1da8a3acd 288 Pfam PF17284 Spermidine synthase tetramerisation domain 7 58 9.0E-15 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THSYN_RS07330 40130d272fcb93e0b0da43b1da8a3acd 288 TIGRFAM TIGR00417 speE: spermidine synthase 7 277 1.1E-76 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THSYN_RS07330 40130d272fcb93e0b0da43b1da8a3acd 288 Gene3D G3DSA:3.40.50.150 61 285 3.1E-37 T 29-03-2018 THSYN_RS15715 4767d6f5b727f6890fd0c268b689450e 521 Gene3D G3DSA:3.40.50.410 65 255 8.6E-27 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS15715 4767d6f5b727f6890fd0c268b689450e 521 SMART SM00327 69 254 6.2E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS15715 4767d6f5b727f6890fd0c268b689450e 521 Pfam PF13519 von Willebrand factor type A domain 72 183 4.0E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS15715 4767d6f5b727f6890fd0c268b689450e 521 SUPERFAMILY SSF53300 72 248 3.34E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS22275 27bf6be2a3c53f5be3773ebf7f7c4340 185 SMART SM00775 27 154 1.2E-9 T 29-03-2018 IPR031315 LNS2/PITP THSYN_RS22275 27bf6be2a3c53f5be3773ebf7f7c4340 185 Gene3D G3DSA:3.40.50.1000 12 35 0.067 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS22275 27bf6be2a3c53f5be3773ebf7f7c4340 185 Pfam PF08235 LNS2 (Lipin/Ned1/Smp2) 52 150 1.5E-8 T 29-03-2018 IPR013209 Lipin/Ned1/Smp2 (LNS2) KEGG: 00561+3.1.3.4|KEGG: 00564+3.1.3.4|KEGG: 00565+3.1.3.4|KEGG: 00600+3.1.3.4|MetaCyc: PWY-6453|MetaCyc: PWY-7782|Reactome: R-HSA-1483191|Reactome: R-HSA-1483213|Reactome: R-HSA-4419969|Reactome: R-HSA-75109 THSYN_RS22275 27bf6be2a3c53f5be3773ebf7f7c4340 185 Gene3D G3DSA:3.40.50.1000 36 154 1.6E-14 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS22275 27bf6be2a3c53f5be3773ebf7f7c4340 185 SUPERFAMILY SSF56784 25 145 4.4E-19 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS22960 365279684b737de8bdf03669950f3ca0 521 SUPERFAMILY SSF53335 14 515 2.5E-97 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS22960 365279684b737de8bdf03669950f3ca0 521 Pfam PF02384 N-6 DNA Methylase 169 460 1.3E-54 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS22960 365279684b737de8bdf03669950f3ca0 521 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 297 309 1.9E-12 T 29-03-2018 THSYN_RS22960 365279684b737de8bdf03669950f3ca0 521 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 215 229 1.9E-12 T 29-03-2018 THSYN_RS22960 365279684b737de8bdf03669950f3ca0 521 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 191 207 1.9E-12 T 29-03-2018 THSYN_RS22960 365279684b737de8bdf03669950f3ca0 521 Gene3D G3DSA:3.40.50.150 189 508 3.0E-49 T 29-03-2018 THSYN_RS22960 365279684b737de8bdf03669950f3ca0 521 Pfam PF12161 HsdM N-terminal domain 17 158 8.4E-13 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS09160 5ecf4d50e360ca0477296bd220b56814 119 Pfam PF06155 Protein of unknown function (DUF971) 8 91 1.6E-28 T 29-03-2018 IPR010376 Domain of unknown function DUF971 Reactome: R-HSA-71262 THSYN_RS31775 1b588979847851f25832cd3552d7b03c 395 PIRSF PIRSF028408 1 395 1.1E-86 T 29-03-2018 IPR014544 Uncharacterised conserved protein UCP028408 THSYN_RS31775 1b588979847851f25832cd3552d7b03c 395 Pfam PF09983 Uncharacterized protein conserved in bacteria C-term(DUF2220) 209 386 1.5E-57 T 29-03-2018 IPR024534 Domain of unknown function DUF2220 THSYN_RS31775 1b588979847851f25832cd3552d7b03c 395 Gene3D G3DSA:3.40.1360.10 236 352 0.0011 T 29-03-2018 THSYN_RS31775 1b588979847851f25832cd3552d7b03c 395 Pfam PF11795 Uncharacterized protein conserved in bacteria N-term (DUF3322) 8 186 9.7E-64 T 29-03-2018 IPR024537 Domain of unknown function DUF3322 THSYN_RS04625 31753fe96e467d5ef662ef6af4ec5fc5 359 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 43 319 1.3E-18 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS04625 31753fe96e467d5ef662ef6af4ec5fc5 359 SUPERFAMILY SSF111369 113 149 1.29E-11 T 29-03-2018 THSYN_RS04625 31753fe96e467d5ef662ef6af4ec5fc5 359 SUPERFAMILY SSF111369 183 326 1.29E-11 T 29-03-2018 THSYN_RS04625 31753fe96e467d5ef662ef6af4ec5fc5 359 SUPERFAMILY SSF111369 42 113 1.83E-6 T 29-03-2018 THSYN_RS04625 31753fe96e467d5ef662ef6af4ec5fc5 359 Gene3D G3DSA:1.20.1600.10 70 305 4.7E-21 T 29-03-2018 THSYN_RS22215 82d7dd79628de2d4b324270186c619cf 166 Pfam PF08534 Redoxin 20 162 1.5E-27 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 THSYN_RS22215 82d7dd79628de2d4b324270186c619cf 166 SUPERFAMILY SSF52833 1 163 4.8E-41 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS22215 82d7dd79628de2d4b324270186c619cf 166 Gene3D G3DSA:3.40.30.10 7 166 5.9E-23 T 29-03-2018 THSYN_RS22215 82d7dd79628de2d4b324270186c619cf 166 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 166 38.018 T 29-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 THSYN_RS22215 82d7dd79628de2d4b324270186c619cf 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 29-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 THSYN_RS18850 1c190e4614bcb3abdfe43dddbcf84600 611 Gene3D G3DSA:1.25.40.10 519 580 7.2E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18850 1c190e4614bcb3abdfe43dddbcf84600 611 Gene3D G3DSA:1.25.40.10 397 518 1.9E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS18850 1c190e4614bcb3abdfe43dddbcf84600 611 Pfam PF13271 Domain of unknown function (DUF4062) 65 160 1.0E-6 T 29-03-2018 IPR025139 Domain of unknown function DUF4062 THSYN_RS18850 1c190e4614bcb3abdfe43dddbcf84600 611 SUPERFAMILY SSF48452 422 560 6.32E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS09390 8877e5011f0ec7874e7ca3a8518b975a 375 SUPERFAMILY SSF51905 1 38 1.75E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS09390 8877e5011f0ec7874e7ca3a8518b975a 375 SUPERFAMILY SSF51905 155 246 1.75E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS09390 8877e5011f0ec7874e7ca3a8518b975a 375 SUPERFAMILY SSF51905 3 107 2.21E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS09390 8877e5011f0ec7874e7ca3a8518b975a 375 SUPERFAMILY SSF51905 241 319 2.21E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS09390 8877e5011f0ec7874e7ca3a8518b975a 375 Gene3D G3DSA:3.50.50.60 150 321 5.7E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS09390 8877e5011f0ec7874e7ca3a8518b975a 375 Gene3D G3DSA:3.50.50.60 1 149 8.2E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS09390 8877e5011f0ec7874e7ca3a8518b975a 375 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 303 1.2E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS33105 d9818e2530afc50a3439bea29448bcd0 284 Gene3D G3DSA:3.20.20.70 2 247 2.3E-28 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS33105 d9818e2530afc50a3439bea29448bcd0 284 Pfam PF04055 Radical SAM superfamily 12 160 7.2E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS33105 d9818e2530afc50a3439bea29448bcd0 284 Pfam PF13353 4Fe-4S single cluster domain 11 110 6.0E-7 T 29-03-2018 THSYN_RS33105 d9818e2530afc50a3439bea29448bcd0 284 SUPERFAMILY SSF102114 6 203 1.2E-33 T 29-03-2018 THSYN_RS22715 24473bffa055cdbc3ebf9c61b59de552 232 TIGRFAM TIGR02807 cas6_cmx6: CRISPR-associated protein Cas6, subtype MYXAN 18 221 2.0E-30 T 29-03-2018 IPR014174 CRISPR-associated protein, Cas6-related THSYN_RS22715 24473bffa055cdbc3ebf9c61b59de552 232 Pfam PF09559 Cas6 Crispr 19 223 3.7E-59 T 29-03-2018 IPR014174 CRISPR-associated protein, Cas6-related THSYN_RS32120 87fd347ba7716b1749b3fb1932bb4f92 112 Pfam PF11848 Domain of unknown function (DUF3368) 62 108 1.4E-15 T 29-03-2018 IPR021799 Protein of unknown function DUF3368 THSYN_RS03655 1860ed09cc470fadb4a01dda2caac790 117 Pfam PF13676 TIR domain 41 101 1.1E-7 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS03655 1860ed09cc470fadb4a01dda2caac790 117 Gene3D G3DSA:3.40.50.10140 3 111 1.0E-10 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS03655 1860ed09cc470fadb4a01dda2caac790 117 SUPERFAMILY SSF52200 3 100 8.37E-8 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS18385 c8dc2b22a7d3e03e845ea10aaf506626 211 TIGRFAM TIGR00608 radc: DNA repair protein RadC 13 208 6.0E-50 T 29-03-2018 IPR001405 RadC protein THSYN_RS18385 c8dc2b22a7d3e03e845ea10aaf506626 211 Gene3D G3DSA:3.40.140.10 97 211 4.1E-34 T 29-03-2018 THSYN_RS18385 c8dc2b22a7d3e03e845ea10aaf506626 211 Pfam PF04002 RadC-like JAB domain 101 209 1.1E-34 T 29-03-2018 IPR025657 RadC-like JAB domain THSYN_RS18385 c8dc2b22a7d3e03e845ea10aaf506626 211 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 169 174 - T 29-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site THSYN_RS26120 81f29ffe9ffeaa065cf9ed68887efb52 165 Pfam PF04355 SmpA / OmlA family 51 117 1.3E-26 T 29-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 THSYN_RS26120 81f29ffe9ffeaa065cf9ed68887efb52 165 Gene3D G3DSA:3.30.1450.10 51 122 8.0E-13 T 29-03-2018 THSYN_RS26120 81f29ffe9ffeaa065cf9ed68887efb52 165 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 13 146 26.361 T 29-03-2018 IPR026592 Outer membrane protein assembly factor BamE THSYN_RS19195 c4135440601c9aa5ba5ea729e6e36ef5 300 Gene3D G3DSA:3.40.50.1980 184 299 1.5E-5 T 29-03-2018 THSYN_RS19195 c4135440601c9aa5ba5ea729e6e36ef5 300 Pfam PF01297 Zinc-uptake complex component A periplasmic 29 298 4.5E-35 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 THSYN_RS19195 c4135440601c9aa5ba5ea729e6e36ef5 300 Gene3D G3DSA:3.40.50.1980 15 183 1.4E-33 T 29-03-2018 THSYN_RS19195 c4135440601c9aa5ba5ea729e6e36ef5 300 SUPERFAMILY SSF53807 24 299 1.13E-46 T 29-03-2018 THSYN_RS09995 f09c53b85259ae1784382edafc40f22b 482 Pfam PF00691 OmpA family 379 469 1.2E-10 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS09995 f09c53b85259ae1784382edafc40f22b 482 Gene3D G3DSA:3.40.190.10 198 318 5.8E-11 T 29-03-2018 THSYN_RS09995 f09c53b85259ae1784382edafc40f22b 482 PRINTS PR01021 OMPA domain signature 411 426 8.3E-5 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS09995 f09c53b85259ae1784382edafc40f22b 482 PRINTS PR01021 OMPA domain signature 426 442 8.3E-5 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS09995 f09c53b85259ae1784382edafc40f22b 482 PRINTS PR01021 OMPA domain signature 379 401 8.3E-5 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS09995 f09c53b85259ae1784382edafc40f22b 482 SUPERFAMILY SSF53850 94 316 9.65E-56 T 29-03-2018 THSYN_RS09995 f09c53b85259ae1784382edafc40f22b 482 SUPERFAMILY SSF53850 30 50 9.65E-56 T 29-03-2018 THSYN_RS09995 f09c53b85259ae1784382edafc40f22b 482 Gene3D G3DSA:3.30.1330.60 319 482 1.7E-19 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS09995 f09c53b85259ae1784382edafc40f22b 482 SUPERFAMILY SSF103088 372 481 8.11E-18 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS09995 f09c53b85259ae1784382edafc40f22b 482 Gene3D G3DSA:3.40.190.10 28 197 1.5E-26 T 29-03-2018 THSYN_RS09995 f09c53b85259ae1784382edafc40f22b 482 Pfam PF12849 PBP superfamily domain 97 309 8.4E-25 T 29-03-2018 IPR024370 PBP domain THSYN_RS12490 1c071df9d8e20051152cbdb2dad20a7b 76 Pfam PF09720 Putative addiction module component 14 66 4.8E-15 T 29-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THSYN_RS12490 1c071df9d8e20051152cbdb2dad20a7b 76 TIGRFAM TIGR02574 stabl_TIGR02574: putative addiction module component, TIGR02574 family 11 70 2.0E-8 T 29-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THSYN_RS07975 166948edeb0c6fa4cab246d4c236ea86 93 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 3 83 20.55 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 THSYN_RS07975 166948edeb0c6fa4cab246d4c236ea86 93 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 49 5.7E-19 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 THSYN_RS07975 166948edeb0c6fa4cab246d4c236ea86 93 Pfam PF02416 mttA/Hcf106 family 8 52 2.3E-12 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 THSYN_RS26850 465422611a295b23e113e263fc11dfaf 135 Gene3D G3DSA:3.40.50.1010 1 134 8.2E-25 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS26850 465422611a295b23e113e263fc11dfaf 135 SUPERFAMILY SSF88723 1 130 1.93E-30 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS26850 465422611a295b23e113e263fc11dfaf 135 Pfam PF01850 PIN domain 3 123 1.8E-11 T 29-03-2018 IPR002716 PIN domain THSYN_RS26850 465422611a295b23e113e263fc11dfaf 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 129 10.361 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS12060 5781fd39bb4215a461031ed52c58ea33 498 Gene3D G3DSA:3.90.350.10 237 405 0.0028 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS12060 5781fd39bb4215a461031ed52c58ea33 498 Pfam PF13751 Transposase DDE domain 353 474 9.1E-19 T 29-03-2018 IPR025668 Transposase DDE domain THSYN_RS12060 5781fd39bb4215a461031ed52c58ea33 498 Pfam PF05598 Transposase domain (DUF772) 59 119 2.2E-12 T 29-03-2018 IPR008490 Transposase InsH, N-terminal THSYN_RS29540 d86f739bbc1e2bfda740ec3ec4cb84f9 42 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 42 1.5E-8 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS29540 d86f739bbc1e2bfda740ec3ec4cb84f9 42 SUPERFAMILY SSF143120 1 42 1.96E-9 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS29540 d86f739bbc1e2bfda740ec3ec4cb84f9 42 Gene3D G3DSA:3.40.1620.10 1 42 9.6E-9 T 29-03-2018 THSYN_RS16995 39aa5a4877563aa3a9c686953553eb7c 264 Pfam PF00072 Response regulator receiver domain 10 122 3.5E-9 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS16995 39aa5a4877563aa3a9c686953553eb7c 264 SMART SM00073 156 254 0.0034 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS16995 39aa5a4877563aa3a9c686953553eb7c 264 SUPERFAMILY SSF47226 144 251 4.19E-23 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS16995 39aa5a4877563aa3a9c686953553eb7c 264 SMART SM00448 8 122 6.1E-12 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS16995 39aa5a4877563aa3a9c686953553eb7c 264 Gene3D G3DSA:1.20.120.160 140 257 1.8E-19 T 29-03-2018 THSYN_RS16995 39aa5a4877563aa3a9c686953553eb7c 264 SUPERFAMILY SSF52172 6 127 2.99E-20 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS16995 39aa5a4877563aa3a9c686953553eb7c 264 Gene3D G3DSA:3.40.50.2300 1 133 3.5E-21 T 29-03-2018 THSYN_RS16995 39aa5a4877563aa3a9c686953553eb7c 264 Pfam PF01627 Hpt domain 166 245 6.8E-13 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS01590 047e5b3aa2adf59e8dafca1f3933e264 476 Pfam PF00919 Uncharacterized protein family UPF0004 43 121 6.4E-18 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 THSYN_RS01590 047e5b3aa2adf59e8dafca1f3933e264 476 SUPERFAMILY SSF102114 150 403 8.24E-51 T 29-03-2018 THSYN_RS01590 047e5b3aa2adf59e8dafca1f3933e264 476 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 177 197 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 THSYN_RS01590 047e5b3aa2adf59e8dafca1f3933e264 476 Pfam PF01938 TRAM domain 411 473 1.1E-4 T 29-03-2018 IPR002792 TRAM domain THSYN_RS01590 047e5b3aa2adf59e8dafca1f3933e264 476 Gene3D G3DSA:2.40.50.140 413 476 1.2E-18 T 29-03-2018 THSYN_RS01590 047e5b3aa2adf59e8dafca1f3933e264 476 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 43 470 1.0E-167 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 THSYN_RS01590 047e5b3aa2adf59e8dafca1f3933e264 476 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 44 471 1.2E-99 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 THSYN_RS01590 047e5b3aa2adf59e8dafca1f3933e264 476 Pfam PF04055 Radical SAM superfamily 179 356 1.6E-27 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS01590 047e5b3aa2adf59e8dafca1f3933e264 476 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 42 473 60.605 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 THSYN_RS01590 047e5b3aa2adf59e8dafca1f3933e264 476 Gene3D G3DSA:3.80.30.20 170 412 1.5E-45 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe THSYN_RS01590 047e5b3aa2adf59e8dafca1f3933e264 476 SMART SM00729 173 398 1.5E-53 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THSYN_RS25650 11653b3c7fda587af12634cc9dac8ff5 246 Pfam PF01936 NYN domain 8 141 2.9E-30 T 29-03-2018 IPR021139 NYN domain, limkain-b1-type THSYN_RS25650 11653b3c7fda587af12634cc9dac8ff5 246 Pfam PF12872 OST-HTH/LOTUS domain 165 231 1.4E-14 T 29-03-2018 IPR025605 OST-HTH/LOTUS domain THSYN_RS25650 11653b3c7fda587af12634cc9dac8ff5 246 Gene3D G3DSA:3.40.50.1010 1 144 9.5E-21 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS27010 311a833eac30cc9b4ef2103cb3a6b31b 214 Gene3D G3DSA:2.40.440.10 95 214 3.1E-27 T 29-03-2018 THSYN_RS27010 311a833eac30cc9b4ef2103cb3a6b31b 214 SUPERFAMILY SSF141523 98 212 1.83E-27 T 29-03-2018 THSYN_RS27010 311a833eac30cc9b4ef2103cb3a6b31b 214 Pfam PF03734 L,D-transpeptidase catalytic domain 104 212 2.1E-18 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 THSYN_RS09010 ef6a24b1515a357edd3f258b2f07d972 951 Pfam PF03781 Sulfatase-modifying factor enzyme 1 691 943 7.0E-46 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS09010 ef6a24b1515a357edd3f258b2f07d972 951 Gene3D G3DSA:3.40.50.300 163 328 1.9E-7 T 29-03-2018 THSYN_RS09010 ef6a24b1515a357edd3f258b2f07d972 951 SUPERFAMILY SSF56436 689 945 1.44E-55 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS09010 ef6a24b1515a357edd3f258b2f07d972 951 SUPERFAMILY SSF52540 180 233 9.93E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09010 ef6a24b1515a357edd3f258b2f07d972 951 SUPERFAMILY SSF52540 263 358 9.93E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09010 ef6a24b1515a357edd3f258b2f07d972 951 Pfam PF05729 NACHT domain 182 360 6.7E-7 T 29-03-2018 THSYN_RS09010 ef6a24b1515a357edd3f258b2f07d972 951 Gene3D G3DSA:3.90.1580.10 680 951 1.3E-55 T 29-03-2018 THSYN_RS11505 6e535dd9906100021b679fc1028474f6 169 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 22 160 2.6E-35 T 29-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN THSYN_RS11505 6e535dd9906100021b679fc1028474f6 169 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 15 164 5.0E-37 T 29-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN THSYN_RS14095 c7a05e1f6b64eb7943d827c11dcd6f3b 350 Gene3D G3DSA:1.10.1610.10 7 72 3.1E-27 T 29-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 THSYN_RS14095 c7a05e1f6b64eb7943d827c11dcd6f3b 350 Pfam PF02277 Phosphoribosyltransferase 13 348 2.8E-128 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 THSYN_RS14095 c7a05e1f6b64eb7943d827c11dcd6f3b 350 SUPERFAMILY SSF52733 6 348 1.57E-115 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 THSYN_RS14095 c7a05e1f6b64eb7943d827c11dcd6f3b 350 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 14 350 36.608 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 THSYN_RS14095 c7a05e1f6b64eb7943d827c11dcd6f3b 350 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 17 348 3.2E-131 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 THSYN_RS14095 c7a05e1f6b64eb7943d827c11dcd6f3b 350 Gene3D G3DSA:3.40.50.10210 73 331 6.8E-102 T 29-03-2018 THSYN_RS30395 b92095c2b08e38a0ed2ee256fe636fee 265 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 24 65 8.0E-8 T 29-03-2018 IPR025159 Transcriptional regulator, AbiEi antitoxin THSYN_RS30395 b92095c2b08e38a0ed2ee256fe636fee 265 Gene3D G3DSA:1.10.10.10 12 65 9.4E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS05630 66d302a3436e78402dee65218292891c 204 Gene3D G3DSA:3.90.950.10 4 195 5.3E-66 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THSYN_RS05630 66d302a3436e78402dee65218292891c 204 Pfam PF02545 Maf-like protein 7 189 1.1E-51 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 THSYN_RS05630 66d302a3436e78402dee65218292891c 204 TIGRFAM TIGR00172 maf: septum formation protein Maf 6 188 6.4E-47 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 THSYN_RS05630 66d302a3436e78402dee65218292891c 204 Hamap MF_00528 Septum formation protein Maf [maf]. 7 195 32.065 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 THSYN_RS05630 66d302a3436e78402dee65218292891c 204 PIRSF PIRSF006305 2 196 7.8E-48 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 THSYN_RS05630 66d302a3436e78402dee65218292891c 204 SUPERFAMILY SSF52972 6 189 1.05E-58 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THSYN_RS17075 6fd826fb6547fc868f554f9c9c243835 249 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 180 214 1.2E-5 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS17075 6fd826fb6547fc868f554f9c9c243835 249 SUPERFAMILY SSF51161 121 233 3.33E-30 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS17075 6fd826fb6547fc868f554f9c9c243835 249 Gene3D G3DSA:2.160.10.10 84 232 4.1E-29 T 29-03-2018 THSYN_RS14720 937c3daa4a6888f7982c34a7a1033a66 935 Pfam PF13244 Domain of unknown function (DUF4040) 612 676 1.1E-21 T 29-03-2018 IPR025383 Domain of unknown function DUF4040 THSYN_RS14720 937c3daa4a6888f7982c34a7a1033a66 935 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 787 910 1.1E-35 T 29-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein THSYN_RS14720 937c3daa4a6888f7982c34a7a1033a66 935 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 123 9.0E-36 T 29-03-2018 THSYN_RS14720 937c3daa4a6888f7982c34a7a1033a66 935 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 150 171 9.0E-36 T 29-03-2018 THSYN_RS14720 937c3daa4a6888f7982c34a7a1033a66 935 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 306 318 9.0E-36 T 29-03-2018 THSYN_RS14720 937c3daa4a6888f7982c34a7a1033a66 935 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 9.0E-36 T 29-03-2018 THSYN_RS14720 937c3daa4a6888f7982c34a7a1033a66 935 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 415 434 9.0E-36 T 29-03-2018 THSYN_RS14720 937c3daa4a6888f7982c34a7a1033a66 935 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 9.0E-36 T 29-03-2018 THSYN_RS14720 937c3daa4a6888f7982c34a7a1033a66 935 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 9.0E-36 T 29-03-2018 THSYN_RS14720 937c3daa4a6888f7982c34a7a1033a66 935 Pfam PF00361 Proton-conducting membrane transporter 126 400 6.0E-64 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS14720 937c3daa4a6888f7982c34a7a1033a66 935 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 113 6.3E-10 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS00545 a351abc64ece44efc2609bfb1ecb169f 270 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 92 120 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 THSYN_RS00545 a351abc64ece44efc2609bfb1ecb169f 270 Pfam PF01464 Transglycosylase SLT domain 75 181 7.3E-30 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 THSYN_RS00545 a351abc64ece44efc2609bfb1ecb169f 270 Gene3D G3DSA:1.10.530.10 22 197 5.0E-37 T 29-03-2018 THSYN_RS00545 a351abc64ece44efc2609bfb1ecb169f 270 SUPERFAMILY SSF53955 70 194 1.06E-36 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS30110 97e67ac29d1178514bdbb3b079bc67c7 749 SUPERFAMILY SSF52540 2 430 2.9E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30110 97e67ac29d1178514bdbb3b079bc67c7 749 SUPERFAMILY SSF52540 463 611 2.9E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30110 97e67ac29d1178514bdbb3b079bc67c7 749 Gene3D G3DSA:3.40.50.300 1 275 8.2E-40 T 29-03-2018 THSYN_RS30110 97e67ac29d1178514bdbb3b079bc67c7 749 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 266 3.0E-35 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 THSYN_RS30110 97e67ac29d1178514bdbb3b079bc67c7 749 Gene3D G3DSA:3.40.50.300 276 638 1.5E-31 T 29-03-2018 THSYN_RS30110 97e67ac29d1178514bdbb3b079bc67c7 749 Pfam PF13361 UvrD-like helicase C-terminal domain 330 604 2.5E-21 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 4.3E-27 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 4.3E-27 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 4.3E-27 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 4.3E-27 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 4.3E-27 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PIRSF PIRSF000350 2 462 1.8E-62 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 325 3.9E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 Gene3D G3DSA:3.30.390.30 333 462 4.3E-31 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 Gene3D G3DSA:3.50.50.60 157 275 7.4E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 SUPERFAMILY SSF51905 5 333 3.89E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 SUPERFAMILY SSF55424 345 462 1.1E-26 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 456 7.6E-25 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 2.9E-47 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 2.9E-47 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 2.9E-47 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 2.9E-47 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 2.9E-47 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.9E-47 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 2.9E-47 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 2.9E-47 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 2.9E-47 T 29-03-2018 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 Gene3D G3DSA:3.50.50.60 3 156 4.9E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS02705 a3acfb2007d05ad871545ea2f6a1dfde 465 Gene3D G3DSA:3.50.50.60 276 332 7.6E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS22340 bbe2b2d62cde07c10c1626078578e046 391 Gene3D G3DSA:1.20.1480.30 28 193 0.016 T 29-03-2018 THSYN_RS03460 3a2027074d7d0b61f1fac813a83d93ef 315 TIGRFAM TIGR00586 mutt: mutator mutT protein 3 129 1.2E-31 T 29-03-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 THSYN_RS03460 3a2027074d7d0b61f1fac813a83d93ef 315 Gene3D G3DSA:3.90.79.10 4 128 6.8E-30 T 29-03-2018 THSYN_RS03460 3a2027074d7d0b61f1fac813a83d93ef 315 SUPERFAMILY SSF51391 117 313 4.05E-48 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THSYN_RS03460 3a2027074d7d0b61f1fac813a83d93ef 315 PRINTS PR00502 NUDIX hydrolase family signature 49 64 1.1E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THSYN_RS03460 3a2027074d7d0b61f1fac813a83d93ef 315 PRINTS PR00502 NUDIX hydrolase family signature 35 49 1.1E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THSYN_RS03460 3a2027074d7d0b61f1fac813a83d93ef 315 SUPERFAMILY SSF55811 2 128 4.6E-37 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 THSYN_RS03460 3a2027074d7d0b61f1fac813a83d93ef 315 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THSYN_RS03460 3a2027074d7d0b61f1fac813a83d93ef 315 Gene3D G3DSA:3.20.20.70 129 315 1.8E-29 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS03460 3a2027074d7d0b61f1fac813a83d93ef 315 Pfam PF14815 NUDIX domain 11 126 4.0E-19 T 29-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 THSYN_RS03460 3a2027074d7d0b61f1fac813a83d93ef 315 Pfam PF02581 Thiamine monophosphate synthase 133 311 2.6E-40 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THSYN_RS18825 0f6d4190ad89b67132e08247b31ef0a4 254 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 12 248 2.5E-58 T 29-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 THSYN_RS06140 46841711e62d77cda198dbd1477e8d86 525 SUPERFAMILY SSF52540 139 240 1.52E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06140 46841711e62d77cda198dbd1477e8d86 525 SUPERFAMILY SSF52540 324 361 1.52E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06140 46841711e62d77cda198dbd1477e8d86 525 Gene3D G3DSA:3.40.50.300 126 362 2.4E-17 T 29-03-2018 THSYN_RS06140 46841711e62d77cda198dbd1477e8d86 525 Pfam PF07728 AAA domain (dynein-related subfamily) 142 240 1.5E-6 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THSYN_RS30310 245ea2c27f5135d3a5ab2449c8c07a54 244 Pfam PF04986 Putative transposase 79 113 7.2E-8 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS17385 30265cc388a7990834f8f7cb0e225af0 410 SUPERFAMILY SSF53756 1 386 1.67E-78 T 29-03-2018 THSYN_RS17385 30265cc388a7990834f8f7cb0e225af0 410 Gene3D G3DSA:3.40.50.2000 32 205 2.1E-15 T 29-03-2018 THSYN_RS17385 30265cc388a7990834f8f7cb0e225af0 410 Pfam PF13439 Glycosyltransferase Family 4 16 199 1.5E-20 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS17385 30265cc388a7990834f8f7cb0e225af0 410 Gene3D G3DSA:3.40.50.2000 206 385 1.4E-44 T 29-03-2018 THSYN_RS17385 30265cc388a7990834f8f7cb0e225af0 410 Pfam PF00534 Glycosyl transferases group 1 217 378 3.5E-39 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS09100 f0bb6da61ddbdd8432d38e57421988c4 522 Gene3D G3DSA:3.30.2010.10 65 160 9.0E-17 T 29-03-2018 THSYN_RS09100 f0bb6da61ddbdd8432d38e57421988c4 522 Gene3D G3DSA:1.25.40.10 268 372 9.1E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS09100 f0bb6da61ddbdd8432d38e57421988c4 522 Gene3D G3DSA:1.25.40.10 373 439 2.3E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS09100 f0bb6da61ddbdd8432d38e57421988c4 522 Pfam PF01435 Peptidase family M48 80 265 4.0E-31 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THSYN_RS09100 f0bb6da61ddbdd8432d38e57421988c4 522 SUPERFAMILY SSF48452 327 467 1.24E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS09100 f0bb6da61ddbdd8432d38e57421988c4 522 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 8 495 34.693 T 29-03-2018 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 THSYN_RS09100 f0bb6da61ddbdd8432d38e57421988c4 522 Gene3D G3DSA:1.20.58.280 440 499 0.13 T 29-03-2018 THSYN_RS09100 f0bb6da61ddbdd8432d38e57421988c4 522 Pfam PF14559 Tetratricopeptide repeat 364 429 3.8E-10 T 29-03-2018 THSYN_RS14080 221d9b4349466124fef756181a383d45 217 PRINTS PR01021 OMPA domain signature 144 159 5.8E-9 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS14080 221d9b4349466124fef756181a383d45 217 PRINTS PR01021 OMPA domain signature 159 175 5.8E-9 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS14080 221d9b4349466124fef756181a383d45 217 PRINTS PR01021 OMPA domain signature 114 136 5.8E-9 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THSYN_RS14080 221d9b4349466124fef756181a383d45 217 SUPERFAMILY SSF103088 109 214 3.79E-30 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS14080 221d9b4349466124fef756181a383d45 217 Gene3D G3DSA:3.30.1330.60 58 217 1.9E-34 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS14080 221d9b4349466124fef756181a383d45 217 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 159 176 2.0E-7 T 29-03-2018 THSYN_RS14080 221d9b4349466124fef756181a383d45 217 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 177 196 2.0E-7 T 29-03-2018 THSYN_RS14080 221d9b4349466124fef756181a383d45 217 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 197 217 2.0E-7 T 29-03-2018 THSYN_RS14080 221d9b4349466124fef756181a383d45 217 Pfam PF00691 OmpA family 114 208 7.8E-20 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS32975 afad235b07e72fdaaf5637700cbc9536 1152 Pfam PF03781 Sulfatase-modifying factor enzyme 1 929 1146 6.8E-41 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS32975 afad235b07e72fdaaf5637700cbc9536 1152 SUPERFAMILY SSF56436 928 1146 1.62E-59 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS32975 afad235b07e72fdaaf5637700cbc9536 1152 Gene3D G3DSA:3.90.1580.10 921 1152 2.8E-54 T 29-03-2018 THSYN_RS32975 afad235b07e72fdaaf5637700cbc9536 1152 SUPERFAMILY SSF56300 2 122 8.39E-19 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS32975 afad235b07e72fdaaf5637700cbc9536 1152 SUPERFAMILY SSF56300 156 311 8.39E-19 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS32975 afad235b07e72fdaaf5637700cbc9536 1152 Gene3D G3DSA:3.60.21.10 3 343 2.3E-19 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS32975 afad235b07e72fdaaf5637700cbc9536 1152 Pfam PF00149 Calcineurin-like phosphoesterase 10 271 1.1E-8 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS02640 d6eb1c6f355ca4be0c421c00c95a63d0 307 Gene3D G3DSA:3.20.10.10 144 296 7.7E-53 T 29-03-2018 THSYN_RS02640 d6eb1c6f355ca4be0c421c00c95a63d0 307 SUPERFAMILY SSF56752 3 304 6.8E-105 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 THSYN_RS02640 d6eb1c6f355ca4be0c421c00c95a63d0 307 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 12 307 1.1E-130 T 29-03-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 THSYN_RS02640 d6eb1c6f355ca4be0c421c00c95a63d0 307 Gene3D G3DSA:3.30.470.10 1 143 4.3E-42 T 29-03-2018 THSYN_RS02640 d6eb1c6f355ca4be0c421c00c95a63d0 307 ProSitePatterns PS00770 Aminotransferases class-IV signature. 195 223 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 THSYN_RS02640 d6eb1c6f355ca4be0c421c00c95a63d0 307 Pfam PF01063 Amino-transferase class IV 37 268 8.8E-54 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 THSYN_RS03845 6f4bb7a7b28274edfe89606a79ed0d56 608 Gene3D G3DSA:3.60.20.10 61 198 1.0E-21 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS03845 6f4bb7a7b28274edfe89606a79ed0d56 608 PIRSF PIRSF001589 61 608 1.9E-88 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS03845 6f4bb7a7b28274edfe89606a79ed0d56 608 Pfam PF00733 Asparagine synthase 238 604 1.9E-73 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THSYN_RS03845 6f4bb7a7b28274edfe89606a79ed0d56 608 Pfam PF13537 Glutamine amidotransferase domain 73 142 1.1E-13 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain THSYN_RS03845 6f4bb7a7b28274edfe89606a79ed0d56 608 Gene3D G3DSA:3.40.50.620 199 608 4.9E-56 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS03845 6f4bb7a7b28274edfe89606a79ed0d56 608 SUPERFAMILY SSF52402 235 362 3.91E-65 T 29-03-2018 THSYN_RS03845 6f4bb7a7b28274edfe89606a79ed0d56 608 SUPERFAMILY SSF52402 458 597 3.91E-65 T 29-03-2018 THSYN_RS03845 6f4bb7a7b28274edfe89606a79ed0d56 608 SUPERFAMILY SSF56235 65 202 6.95E-23 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS19220 63ab8c94f0f46230d3c4a71ef7d161a7 79 SUPERFAMILY SSF47598 1 39 9.78E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS19220 63ab8c94f0f46230d3c4a71ef7d161a7 79 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 6 66 1.4E-4 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS19220 63ab8c94f0f46230d3c4a71ef7d161a7 79 Gene3D G3DSA:1.10.1220.10 4 48 1.7E-8 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS02710 47ead07d0a4a2e8fa0061684187a89dd 403 Gene3D G3DSA:1.20.1250.20 199 397 1.5E-10 T 29-03-2018 THSYN_RS02710 47ead07d0a4a2e8fa0061684187a89dd 403 Gene3D G3DSA:1.20.1250.20 2 194 1.5E-31 T 29-03-2018 THSYN_RS02710 47ead07d0a4a2e8fa0061684187a89dd 403 SUPERFAMILY SSF103473 3 392 5.1E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS02710 47ead07d0a4a2e8fa0061684187a89dd 403 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 7 385 4.3E-93 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 THSYN_RS02710 47ead07d0a4a2e8fa0061684187a89dd 403 Pfam PF07690 Major Facilitator Superfamily 13 354 3.5E-41 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THSYN_RS00985 048a4b41fa087d6788f13e51b498f9f4 229 Gene3D G3DSA:3.40.50.10420 34 229 1.3E-53 T 29-03-2018 THSYN_RS00985 048a4b41fa087d6788f13e51b498f9f4 229 SUPERFAMILY SSF100950 38 227 2.65E-49 T 29-03-2018 THSYN_RS00985 048a4b41fa087d6788f13e51b498f9f4 229 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 38 221 2.2E-43 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase THSYN_RS00985 048a4b41fa087d6788f13e51b498f9f4 229 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 37 221 1.0E-34 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase THSYN_RS00985 048a4b41fa087d6788f13e51b498f9f4 229 PIRSF PIRSF006806 34 224 1.4E-28 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase THSYN_RS29490 b04650bc5c80a169e84f2f3a5c75a4f7 547 Pfam PF14574 Domain of unknown function (DUF4445) 137 537 7.0E-102 T 29-03-2018 IPR027980 Protein of unknown function DUF4445 THSYN_RS29490 b04650bc5c80a169e84f2f3a5c75a4f7 547 Gene3D G3DSA:3.10.20.30 2 107 1.5E-16 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS29490 b04650bc5c80a169e84f2f3a5c75a4f7 547 Gene3D G3DSA:3.30.420.40 128 286 3.2E-6 T 29-03-2018 THSYN_RS29490 b04650bc5c80a169e84f2f3a5c75a4f7 547 SUPERFAMILY SSF54292 4 92 2.22E-17 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS29490 b04650bc5c80a169e84f2f3a5c75a4f7 547 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 27 84 2.0E-8 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS29490 b04650bc5c80a169e84f2f3a5c75a4f7 547 SUPERFAMILY SSF53067 195 240 8.03E-7 T 29-03-2018 THSYN_RS29490 b04650bc5c80a169e84f2f3a5c75a4f7 547 SUPERFAMILY SSF53067 139 167 8.03E-7 T 29-03-2018 THSYN_RS29490 b04650bc5c80a169e84f2f3a5c75a4f7 547 SUPERFAMILY SSF53067 286 354 8.03E-7 T 29-03-2018 THSYN_RS08480 b64aa0e7b915d6011d480341f407c0d4 601 Pfam PF03814 Potassium-transporting ATPase A subunit 11 590 1.3E-244 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 THSYN_RS08480 b64aa0e7b915d6011d480341f407c0d4 601 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 243 591 4.1E-164 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 THSYN_RS08480 b64aa0e7b915d6011d480341f407c0d4 601 PIRSF PIRSF001294 1 594 2.1E-241 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 THSYN_RS08480 b64aa0e7b915d6011d480341f407c0d4 601 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 592 35.942 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 THSYN_RS23705 b058d4b73d2fcb0d226cadc3adb3b0b0 524 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 15 31 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS23705 b058d4b73d2fcb0d226cadc3adb3b0b0 524 SMART SM00917 370 508 6.3E-11 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS23705 b058d4b73d2fcb0d226cadc3adb3b0b0 524 Gene3D G3DSA:3.20.20.70 7 325 1.3E-81 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS23705 b058d4b73d2fcb0d226cadc3adb3b0b0 524 Pfam PF00682 HMGL-like 8 275 2.4E-48 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 THSYN_RS23705 b058d4b73d2fcb0d226cadc3adb3b0b0 524 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 204 217 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS23705 b058d4b73d2fcb0d226cadc3adb3b0b0 524 SUPERFAMILY SSF51569 4 292 4.94E-68 T 29-03-2018 THSYN_RS23705 b058d4b73d2fcb0d226cadc3adb3b0b0 524 SUPERFAMILY SSF110921 394 506 1.31E-11 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS23705 b058d4b73d2fcb0d226cadc3adb3b0b0 524 Pfam PF08502 LeuA allosteric (dimerisation) domain 371 506 1.0E-20 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS20910 9e03555b4abdf4e2149833a451548749 253 Gene3D G3DSA:3.30.2010.10 52 210 0.0011 T 29-03-2018 THSYN_RS20910 9e03555b4abdf4e2149833a451548749 253 Pfam PF01863 Protein of unknown function DUF45 22 227 2.3E-56 T 29-03-2018 IPR002725 Protein of unknown function DUF45 THSYN_RS24375 ce5794a596c27fffb5b5aa7768046690 109 Gene3D G3DSA:2.10.109.10 2 102 3.0E-10 T 29-03-2018 THSYN_RS24375 ce5794a596c27fffb5b5aa7768046690 109 Pfam PF00717 Peptidase S24-like 20 86 9.3E-7 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THSYN_RS24375 ce5794a596c27fffb5b5aa7768046690 109 SUPERFAMILY SSF51306 15 99 2.44E-15 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THSYN_RS18950 dabb2c06165205bd74f20c1461d37a97 237 SMART SM00448 5 115 1.2E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18950 dabb2c06165205bd74f20c1461d37a97 237 Gene3D G3DSA:3.40.50.2300 1 123 9.3E-36 T 29-03-2018 THSYN_RS18950 dabb2c06165205bd74f20c1461d37a97 237 Gene3D G3DSA:1.10.10.10 124 237 2.4E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS18950 dabb2c06165205bd74f20c1461d37a97 237 SUPERFAMILY SSF46894 137 231 4.25E-26 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS18950 dabb2c06165205bd74f20c1461d37a97 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 1.6E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS18950 dabb2c06165205bd74f20c1461d37a97 237 Pfam PF00072 Response regulator receiver domain 7 115 1.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS18950 dabb2c06165205bd74f20c1461d37a97 237 SMART SM00862 154 230 7.2E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS18950 dabb2c06165205bd74f20c1461d37a97 237 SUPERFAMILY SSF52172 3 128 2.99E-41 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS32915 b5579a064988e46b975672a51ddf78da 85 Gene3D G3DSA:3.40.1620.10 1 51 8.5E-15 T 29-03-2018 THSYN_RS32915 b5579a064988e46b975672a51ddf78da 85 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 2 66 8.1E-17 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS32915 b5579a064988e46b975672a51ddf78da 85 SUPERFAMILY SSF143120 2 48 1.44E-11 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS32915 b5579a064988e46b975672a51ddf78da 85 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 50 3.2E-11 T 29-03-2018 THSYN_RS22635 1bde0d1361b2095b17c77092ce7315b9 104 SUPERFAMILY SSF89360 1 94 1.02E-13 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS22635 1bde0d1361b2095b17c77092ce7315b9 104 Gene3D G3DSA:2.60.300.12 1 99 1.1E-15 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS22635 1bde0d1361b2095b17c77092ce7315b9 104 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 80 3.5E-6 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THSYN_RS19970 433382b849b365f6d09c3c8715266268 569 Gene3D G3DSA:3.40.50.300 11 239 3.1E-38 T 29-03-2018 THSYN_RS19970 433382b849b365f6d09c3c8715266268 569 Gene3D G3DSA:3.40.50.300 248 471 5.0E-35 T 29-03-2018 THSYN_RS19970 433382b849b365f6d09c3c8715266268 569 Pfam PF06745 KaiC 11 236 2.1E-65 T 29-03-2018 IPR014774 KaiC-like domain THSYN_RS19970 433382b849b365f6d09c3c8715266268 569 Pfam PF06745 KaiC 250 466 7.8E-34 T 29-03-2018 IPR014774 KaiC-like domain THSYN_RS19970 433382b849b365f6d09c3c8715266268 569 SUPERFAMILY SSF52540 246 466 4.13E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19970 433382b849b365f6d09c3c8715266268 569 SMART SM00382 268 506 0.33 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS19970 433382b849b365f6d09c3c8715266268 569 SMART SM00382 27 199 2.2 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS19970 433382b849b365f6d09c3c8715266268 569 PRINTS PR01874 DNA repair protein radA signature 167 195 1.3E-5 T 29-03-2018 THSYN_RS19970 433382b849b365f6d09c3c8715266268 569 PRINTS PR01874 DNA repair protein radA signature 19 47 1.3E-5 T 29-03-2018 THSYN_RS19970 433382b849b365f6d09c3c8715266268 569 PIRSF PIRSF039117 2 495 1.2E-141 T 29-03-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 THSYN_RS19970 433382b849b365f6d09c3c8715266268 569 SUPERFAMILY SSF52540 5 235 3.63E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13155 e1e73f04fc185373b4d7dabe9b1763e2 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 4.3E-84 T 29-03-2018 THSYN_RS13155 e1e73f04fc185373b4d7dabe9b1763e2 258 PIRSF PIRSF000094 1 258 4.0E-111 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THSYN_RS13155 e1e73f04fc185373b4d7dabe9b1763e2 258 SUPERFAMILY SSF51735 5 254 1.15E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS13155 e1e73f04fc185373b4d7dabe9b1763e2 258 Gene3D G3DSA:3.40.50.720 3 256 3.9E-42 T 29-03-2018 THSYN_RS13155 e1e73f04fc185373b4d7dabe9b1763e2 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 8.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS13155 e1e73f04fc185373b4d7dabe9b1763e2 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 8.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS13155 e1e73f04fc185373b4d7dabe9b1763e2 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 8.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS13155 e1e73f04fc185373b4d7dabe9b1763e2 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 8.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS10525 48220f4b0ba89a5bd14f455037a57538 400 SUPERFAMILY SSF51197 10 296 5.22E-53 T 29-03-2018 THSYN_RS10525 48220f4b0ba89a5bd14f455037a57538 400 Gene3D G3DSA:2.60.120.650 2 217 3.0E-21 T 29-03-2018 THSYN_RS10525 48220f4b0ba89a5bd14f455037a57538 400 Pfam PF08007 Cupin superfamily protein 18 315 2.3E-67 T 29-03-2018 IPR003347 JmjC domain THSYN_RS01005 afaeb98571fb283a9786a385d5e01357 177 SUPERFAMILY SSF101327 3 168 1.96E-29 T 29-03-2018 IPR011978 Uncharacterised protein family UPF0149 THSYN_RS01005 afaeb98571fb283a9786a385d5e01357 177 Pfam PF03695 Uncharacterised protein family (UPF0149) 1 168 7.4E-33 T 29-03-2018 IPR011978 Uncharacterised protein family UPF0149 THSYN_RS13805 e90f03f6fc1c4c584186133bff2e816a 251 SMART SM00244 19 176 6.1E-61 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS13805 e90f03f6fc1c4c584186133bff2e816a 251 PRINTS PR00721 Stomatin signature 171 192 1.4E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS13805 e90f03f6fc1c4c584186133bff2e816a 251 PRINTS PR00721 Stomatin signature 152 170 1.4E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS13805 e90f03f6fc1c4c584186133bff2e816a 251 PRINTS PR00721 Stomatin signature 196 219 1.4E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS13805 e90f03f6fc1c4c584186133bff2e816a 251 PRINTS PR00721 Stomatin signature 73 94 1.4E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS13805 e90f03f6fc1c4c584186133bff2e816a 251 PRINTS PR00721 Stomatin signature 26 48 1.4E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS13805 e90f03f6fc1c4c584186133bff2e816a 251 PRINTS PR00721 Stomatin signature 108 125 1.4E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS13805 e90f03f6fc1c4c584186133bff2e816a 251 PRINTS PR00721 Stomatin signature 128 151 1.4E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 THSYN_RS13805 e90f03f6fc1c4c584186133bff2e816a 251 SUPERFAMILY SSF117892 50 183 3.79E-43 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS13805 e90f03f6fc1c4c584186133bff2e816a 251 Pfam PF01145 SPFH domain / Band 7 family 24 192 4.2E-33 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS22955 53ca78eb4cc30a29bee043f3f532da32 381 SUPERFAMILY SSF116734 218 381 8.18E-15 T 29-03-2018 THSYN_RS22955 53ca78eb4cc30a29bee043f3f532da32 381 Gene3D G3DSA:3.90.220.20 24 169 2.0E-11 T 29-03-2018 THSYN_RS22955 53ca78eb4cc30a29bee043f3f532da32 381 Gene3D G3DSA:3.90.220.20 179 364 1.2E-9 T 29-03-2018 THSYN_RS22955 53ca78eb4cc30a29bee043f3f532da32 381 SUPERFAMILY SSF116734 57 169 1.41E-10 T 29-03-2018 THSYN_RS21975 2b3b418808e6b7a8202b0ffff0b06965 387 SUPERFAMILY SSF53756 7 373 8.97E-33 T 29-03-2018 THSYN_RS21975 2b3b418808e6b7a8202b0ffff0b06965 387 Gene3D G3DSA:3.40.50.2000 183 376 8.7E-12 T 29-03-2018 THSYN_RS21975 2b3b418808e6b7a8202b0ffff0b06965 387 Pfam PF02684 Lipid-A-disaccharide synthetase 10 377 5.0E-105 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 THSYN_RS21975 2b3b418808e6b7a8202b0ffff0b06965 387 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 9 381 1.2E-105 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 THSYN_RS21975 2b3b418808e6b7a8202b0ffff0b06965 387 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 5 383 38.977 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 THSYN_RS21975 2b3b418808e6b7a8202b0ffff0b06965 387 Gene3D G3DSA:3.40.50.2000 1 182 5.4E-8 T 29-03-2018 THSYN_RS28120 56e4cbddc2bc3cbe2d4527eef2872b8c 277 Gene3D G3DSA:2.40.50.140 185 276 1.7E-8 T 29-03-2018 THSYN_RS28120 56e4cbddc2bc3cbe2d4527eef2872b8c 277 Pfam PF01936 NYN domain 6 161 1.1E-26 T 29-03-2018 IPR021139 NYN domain, limkain-b1-type THSYN_RS28120 56e4cbddc2bc3cbe2d4527eef2872b8c 277 Gene3D G3DSA:3.40.50.1010 1 162 1.5E-24 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS12145 1d4ec535b840b2f7b137596438cb6fa0 447 SUPERFAMILY SSF49879 327 444 3.25E-23 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 THSYN_RS12145 1d4ec535b840b2f7b137596438cb6fa0 447 Gene3D G3DSA:2.60.200.20 353 447 3.1E-20 T 29-03-2018 THSYN_RS12145 1d4ec535b840b2f7b137596438cb6fa0 447 Pfam PF13365 Trypsin-like peptidase domain 68 218 4.7E-24 T 29-03-2018 THSYN_RS12145 1d4ec535b840b2f7b137596438cb6fa0 447 Gene3D G3DSA:2.40.10.10 41 139 2.4E-12 T 29-03-2018 THSYN_RS12145 1d4ec535b840b2f7b137596438cb6fa0 447 SUPERFAMILY SSF50494 47 273 8.32E-31 T 29-03-2018 IPR009003 Peptidase S1, PA clan THSYN_RS12145 1d4ec535b840b2f7b137596438cb6fa0 447 PRINTS PR00834 HtrA/DegQ protease family signature 189 206 7.9E-12 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS12145 1d4ec535b840b2f7b137596438cb6fa0 447 PRINTS PR00834 HtrA/DegQ protease family signature 211 228 7.9E-12 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS12145 1d4ec535b840b2f7b137596438cb6fa0 447 PRINTS PR00834 HtrA/DegQ protease family signature 79 91 7.9E-12 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS12145 1d4ec535b840b2f7b137596438cb6fa0 447 PRINTS PR00834 HtrA/DegQ protease family signature 105 125 7.9E-12 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS12145 1d4ec535b840b2f7b137596438cb6fa0 447 SMART SM00240 364 419 1.2E-8 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THSYN_RS12145 1d4ec535b840b2f7b137596438cb6fa0 447 Gene3D G3DSA:2.40.10.10 140 276 1.1E-19 T 29-03-2018 THSYN_RS12145 1d4ec535b840b2f7b137596438cb6fa0 447 Pfam PF00498 FHA domain 366 435 1.0E-13 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THSYN_RS30690 a7f0e19455742eb2f5bbaf2e3145ba15 369 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 14 365 3.7E-85 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 THSYN_RS30690 a7f0e19455742eb2f5bbaf2e3145ba15 369 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 9 367 50.064 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 THSYN_RS30690 a7f0e19455742eb2f5bbaf2e3145ba15 369 Pfam PF00155 Aminotransferase class I and II 41 353 6.4E-48 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THSYN_RS30690 a7f0e19455742eb2f5bbaf2e3145ba15 369 Gene3D G3DSA:3.40.640.10 66 258 5.2E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS30690 a7f0e19455742eb2f5bbaf2e3145ba15 369 SUPERFAMILY SSF53383 7 368 6.46E-80 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS30690 a7f0e19455742eb2f5bbaf2e3145ba15 369 Gene3D G3DSA:3.90.1150.10 259 366 9.9E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS01010 1962fe1366ec58546b8a0b57b93b4044 434 SUPERFAMILY SSF53092 2 173 3.66E-51 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal THSYN_RS01010 1962fe1366ec58546b8a0b57b93b4044 434 Pfam PF05195 Aminopeptidase P, N-terminal domain 6 122 3.8E-36 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 THSYN_RS01010 1962fe1366ec58546b8a0b57b93b4044 434 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 347 359 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site THSYN_RS01010 1962fe1366ec58546b8a0b57b93b4044 434 SMART SM01011 1 135 2.3E-61 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 THSYN_RS01010 1962fe1366ec58546b8a0b57b93b4044 434 PRINTS PR00599 Methionine aminopeptidase-1 signature 252 268 6.8E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THSYN_RS01010 1962fe1366ec58546b8a0b57b93b4044 434 PRINTS PR00599 Methionine aminopeptidase-1 signature 370 382 6.8E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THSYN_RS01010 1962fe1366ec58546b8a0b57b93b4044 434 Pfam PF00557 Metallopeptidase family M24 180 411 3.1E-67 T 29-03-2018 IPR000994 Peptidase M24 THSYN_RS01010 1962fe1366ec58546b8a0b57b93b4044 434 Gene3D G3DSA:3.40.350.10 1 170 6.3E-47 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal THSYN_RS01010 1962fe1366ec58546b8a0b57b93b4044 434 SUPERFAMILY SSF55920 175 433 7.46E-87 T 29-03-2018 IPR000994 Peptidase M24 THSYN_RS01010 1962fe1366ec58546b8a0b57b93b4044 434 Gene3D G3DSA:3.90.230.10 171 434 2.6E-87 T 29-03-2018 THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 723 829 2.2E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 Gene3D G3DSA:3.30.450.20 514 592 0.046 T 29-03-2018 THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 SMART SM00091 367 434 1.4E-6 T 29-03-2018 IPR000014 PAS domain THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 SMART SM00091 490 555 25.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 SMART SM00091 604 674 280.0 T 29-03-2018 IPR000014 PAS domain THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 Pfam PF13426 PAS domain 378 481 1.7E-13 T 29-03-2018 IPR000014 PAS domain THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 Gene3D G3DSA:3.30.450.20 485 513 0.0018 T 29-03-2018 THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 363 489 4.9E-23 T 29-03-2018 IPR000014 PAS domain THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 SMART SM00388 608 678 8.0E-5 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 Gene3D G3DSA:3.30.450.20 352 484 1.0E-25 T 29-03-2018 THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 SMART SM00387 720 830 2.4E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 Pfam PF00512 His Kinase A (phospho-acceptor) domain 609 672 2.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 PRINTS PR00344 Bacterial sensor protein C-terminal signature 779 789 4.0E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 PRINTS PR00344 Bacterial sensor protein C-terminal signature 790 808 4.0E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 PRINTS PR00344 Bacterial sensor protein C-terminal signature 761 775 4.0E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 PRINTS PR00344 Bacterial sensor protein C-terminal signature 814 827 4.0E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 Gene3D G3DSA:3.30.565.10 680 833 7.1E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 SUPERFAMILY SSF55874 675 829 3.67E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 SUPERFAMILY SSF55785 378 490 2.27E-22 T 29-03-2018 IPR000014 PAS domain THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 Gene3D G3DSA:1.10.287.130 593 673 6.8E-9 T 29-03-2018 THSYN_RS10255 d6d694ad7994102925030f27676a6972 849 SUPERFAMILY SSF47384 605 672 1.51E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS05805 1a3633322eb32305f99ac7b4f1a048a3 437 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 195 434 7.3E-64 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 THSYN_RS05805 1a3633322eb32305f99ac7b4f1a048a3 437 Gene3D G3DSA:1.10.3720.10 23 427 1.2E-46 T 29-03-2018 THSYN_RS05805 1a3633322eb32305f99ac7b4f1a048a3 437 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 235 436 4.7E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS05805 1a3633322eb32305f99ac7b4f1a048a3 437 Pfam PF11812 Domain of unknown function (DUF3333) 22 171 7.5E-53 T 29-03-2018 IPR024573 Domain of unknown function DUF3333 THSYN_RS05805 1a3633322eb32305f99ac7b4f1a048a3 437 SUPERFAMILY SSF161098 213 424 2.75E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS00460 4f410106c04800bba5a15a5ff90fc307 227 TIGRFAM TIGR03306 altF1_A: alternate F1F0 ATPase, F0 subunit A 3 219 8.9E-114 T 29-03-2018 IPR017692 Alternate ATP synthase, F0complex, subunit A THSYN_RS00460 4f410106c04800bba5a15a5ff90fc307 227 PRINTS PR00123 ATP synthase A subunit signature 157 179 3.0E-15 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00460 4f410106c04800bba5a15a5ff90fc307 227 PRINTS PR00123 ATP synthase A subunit signature 201 216 3.0E-15 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00460 4f410106c04800bba5a15a5ff90fc307 227 PRINTS PR00123 ATP synthase A subunit signature 81 97 3.0E-15 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00460 4f410106c04800bba5a15a5ff90fc307 227 PRINTS PR00123 ATP synthase A subunit signature 141 156 3.0E-15 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00460 4f410106c04800bba5a15a5ff90fc307 227 Gene3D G3DSA:1.20.120.220 54 221 1.5E-35 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00460 4f410106c04800bba5a15a5ff90fc307 227 SUPERFAMILY SSF81336 77 214 9.81E-34 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00460 4f410106c04800bba5a15a5ff90fc307 227 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 22 216 1.1E-31 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00460 4f410106c04800bba5a15a5ff90fc307 227 ProSitePatterns PS00449 ATP synthase a subunit signature. 160 169 - T 29-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00460 4f410106c04800bba5a15a5ff90fc307 227 Pfam PF00119 ATP synthase A chain 23 214 3.8E-43 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00460 4f410106c04800bba5a15a5ff90fc307 227 Hamap MF_01393 ATP synthase subunit a [atpB]. 9 221 13.181 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS21635 19e1d402d3f149568009fed447585660 488 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 485 2.3E-156 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THSYN_RS21635 19e1d402d3f149568009fed447585660 488 Pfam PF08323 Starch synthase catalytic domain 3 242 1.8E-68 T 29-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THSYN_RS21635 19e1d402d3f149568009fed447585660 488 SUPERFAMILY SSF53756 3 488 2.17E-108 T 29-03-2018 THSYN_RS21635 19e1d402d3f149568009fed447585660 488 Pfam PF00534 Glycosyl transferases group 1 298 443 1.3E-9 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS21635 19e1d402d3f149568009fed447585660 488 Gene3D G3DSA:3.40.50.2000 256 482 9.2E-30 T 29-03-2018 THSYN_RS21635 19e1d402d3f149568009fed447585660 488 Hamap MF_00484 Glycogen synthase [glgA]. 1 486 38.427 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THSYN_RS02325 bf39560b7ccc789bf0a4c1dbc68178c6 454 SUPERFAMILY SSF52540 38 152 4.72E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02325 bf39560b7ccc789bf0a4c1dbc68178c6 454 Gene3D G3DSA:3.40.50.300 18 210 0.0016 T 29-03-2018 THSYN_RS20715 6253c1a5feb5b61a7d343838975bc796 369 Pfam PF13511 Domain of unknown function (DUF4124) 46 106 9.6E-11 T 29-03-2018 IPR025392 Domain of unknown function DUF4124 THSYN_RS23290 801f9a7a0951d70e90a1b11fcf28b5bd 538 Pfam PF14707 C-terminal region of aryl-sulfatase 418 524 2.4E-10 T 29-03-2018 THSYN_RS23290 801f9a7a0951d70e90a1b11fcf28b5bd 538 Pfam PF00884 Sulfatase 47 376 2.8E-59 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THSYN_RS23290 801f9a7a0951d70e90a1b11fcf28b5bd 538 Gene3D G3DSA:3.30.1120.10 416 513 2.5E-19 T 29-03-2018 THSYN_RS23290 801f9a7a0951d70e90a1b11fcf28b5bd 538 SUPERFAMILY SSF53649 43 530 2.22E-115 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS23290 801f9a7a0951d70e90a1b11fcf28b5bd 538 Gene3D G3DSA:3.40.720.10 274 415 1.9E-29 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS23290 801f9a7a0951d70e90a1b11fcf28b5bd 538 Gene3D G3DSA:3.40.720.10 43 273 1.5E-46 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS22805 ef61a817e4e2cce8a55b974070286066 150 SUPERFAMILY SSF53163 1 147 3.53E-25 T 29-03-2018 IPR023430 Peptidase HybD-like domain THSYN_RS22805 ef61a817e4e2cce8a55b974070286066 150 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 2 144 1.4E-20 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS22805 ef61a817e4e2cce8a55b974070286066 150 Gene3D G3DSA:3.40.50.1450 1 150 7.0E-22 T 29-03-2018 IPR023430 Peptidase HybD-like domain THSYN_RS03890 5e8191c36cb3a7a157a035a0fac97146 345 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 345 1.5E-127 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THSYN_RS03890 5e8191c36cb3a7a157a035a0fac97146 345 SUPERFAMILY SSF55347 149 313 1.07E-49 T 29-03-2018 THSYN_RS03890 5e8191c36cb3a7a157a035a0fac97146 345 Gene3D G3DSA:3.30.360.10 159 313 9.4E-56 T 29-03-2018 THSYN_RS03890 5e8191c36cb3a7a157a035a0fac97146 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 316 7.9E-18 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THSYN_RS03890 5e8191c36cb3a7a157a035a0fac97146 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 140 1.3E-34 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THSYN_RS03890 5e8191c36cb3a7a157a035a0fac97146 345 SMART SM00859 3 141 7.3E-61 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THSYN_RS03890 5e8191c36cb3a7a157a035a0fac97146 345 SUPERFAMILY SSF51735 2 173 2.88E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS03890 5e8191c36cb3a7a157a035a0fac97146 345 Gene3D G3DSA:3.40.50.720 1 158 4.8E-45 T 29-03-2018 THSYN_RS03890 5e8191c36cb3a7a157a035a0fac97146 345 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 29-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THSYN_RS03890 5e8191c36cb3a7a157a035a0fac97146 345 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 339 41.983 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THSYN_RS26095 78be1f7217ea07ca7fa3336e7728f394 161 Pfam PF13635 Domain of unknown function (DUF4143) 4 102 1.1E-20 T 29-03-2018 IPR025420 Domain of unknown function DUF4143 THSYN_RS19620 9ebb5c0958bd6e0d2e8ccf84abd2aa72 224 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 217 18.582 T 29-03-2018 IPR006008 Intracellular septation protein A GO:0016021 THSYN_RS19620 9ebb5c0958bd6e0d2e8ccf84abd2aa72 224 Pfam PF04279 Intracellular septation protein A 1 216 3.3E-61 T 29-03-2018 IPR006008 Intracellular septation protein A GO:0016021 THSYN_RS06765 10afc3a90f24771818d28643310f2b3f 1410 Gene3D G3DSA:3.30.420.40 688 871 5.1E-4 T 29-03-2018 THSYN_RS06765 10afc3a90f24771818d28643310f2b3f 1410 Gene3D G3DSA:3.30.420.40 872 1325 0.0032 T 29-03-2018 THSYN_RS03605 f1db34b44b862d17fbcf62de07a2b034 118 Pfam PF13391 HNH endonuclease 18 62 2.4E-6 T 29-03-2018 IPR003615 HNH nuclease THSYN_RS02415 323ad1e42adb28304a299481608865b7 460 Gene3D G3DSA:1.20.1250.20 207 402 9.6E-15 T 29-03-2018 THSYN_RS02415 323ad1e42adb28304a299481608865b7 460 Pfam PF07690 Major Facilitator Superfamily 25 273 5.8E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THSYN_RS02415 323ad1e42adb28304a299481608865b7 460 SUPERFAMILY SSF103473 15 394 1.31E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS02415 323ad1e42adb28304a299481608865b7 460 Gene3D G3DSA:1.20.1250.20 15 206 7.6E-31 T 29-03-2018 THSYN_RS05290 bbd1f95b91fd0184a12a101a71a06613 382 Pfam PF15608 PELOTA RNA binding domain 288 365 7.4E-26 T 29-03-2018 IPR028157 PELOTA RNA-binding domain THSYN_RS05290 bbd1f95b91fd0184a12a101a71a06613 382 Gene3D G3DSA:3.40.50.2020 70 213 4.2E-4 T 29-03-2018 THSYN_RS05290 bbd1f95b91fd0184a12a101a71a06613 382 PIRSF PIRSF020979 7 370 9.0E-102 T 29-03-2018 IPR011215 Phosphoribosyl transferase THSYN_RS05290 bbd1f95b91fd0184a12a101a71a06613 382 Pfam PF11202 Phosphoribosyl transferase (PRTase) 16 264 1.1E-90 T 29-03-2018 IPR011215 Phosphoribosyl transferase THSYN_RS18920 abf71ab84f51b25f0616bcb511a53707 203 Gene3D G3DSA:1.20.1260.10 39 202 2.7E-21 T 29-03-2018 IPR012347 Ferritin-related THSYN_RS18920 abf71ab84f51b25f0616bcb511a53707 203 Pfam PF09968 Uncharacterized protein domain (DUF2202) 46 201 8.6E-54 T 29-03-2018 IPR019243 Domain of unknown function DUF2202 THSYN_RS18920 abf71ab84f51b25f0616bcb511a53707 203 SUPERFAMILY SSF47240 47 182 2.38E-12 T 29-03-2018 IPR009078 Ferritin-like superfamily THSYN_RS01960 b4a36f823840ec1f3f234f236d4dd921 457 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 13 457 5.4E-113 T 29-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase THSYN_RS01960 b4a36f823840ec1f3f234f236d4dd921 457 Pfam PF02397 Bacterial sugar transferase 266 451 1.3E-63 T 29-03-2018 IPR003362 Bacterial sugar transferase THSYN_RS01960 b4a36f823840ec1f3f234f236d4dd921 457 TIGRFAM TIGR03013 EpsB_2: sugar transferase, PEP-CTERM system associated 11 457 5.8E-153 T 29-03-2018 IPR017464 Sugar transferase, PEP-CTERM system associated THSYN_RS01960 b4a36f823840ec1f3f234f236d4dd921 457 Gene3D G3DSA:3.40.50.20 126 222 2.8E-6 T 29-03-2018 THSYN_RS02100 b1e0d5bc55017b3873e5f5f80621dcc2 311 Gene3D G3DSA:3.40.50.300 46 288 5.0E-61 T 29-03-2018 THSYN_RS02100 b1e0d5bc55017b3873e5f5f80621dcc2 311 SMART SM00382 73 262 2.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS02100 b1e0d5bc55017b3873e5f5f80621dcc2 311 SUPERFAMILY SSF52540 48 274 7.85E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02100 b1e0d5bc55017b3873e5f5f80621dcc2 311 ProSitePatterns PS00211 ABC transporters family signature. 185 199 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS02100 b1e0d5bc55017b3873e5f5f80621dcc2 311 Pfam PF00005 ABC transporter 65 212 4.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS30645 9b7a4a893776d509d2186d7a52303310 725 SMART SM00304 342 395 1.0E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS30645 9b7a4a893776d509d2186d7a52303310 725 Gene3D G3DSA:3.30.450.20 94 192 4.7E-5 T 29-03-2018 THSYN_RS30645 9b7a4a893776d509d2186d7a52303310 725 Pfam PF02743 Cache domain 48 304 5.9E-17 T 29-03-2018 IPR033479 Double Cache domain 1 THSYN_RS30645 9b7a4a893776d509d2186d7a52303310 725 Pfam PF00672 HAMP domain 343 392 4.5E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS30645 9b7a4a893776d509d2186d7a52303310 725 SUPERFAMILY SSF81606 442 647 1.96E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS30645 9b7a4a893776d509d2186d7a52303310 725 SUPERFAMILY SSF158472 343 393 7.98E-10 T 29-03-2018 THSYN_RS30645 9b7a4a893776d509d2186d7a52303310 725 SMART SM00331 432 649 4.9E-49 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS30645 9b7a4a893776d509d2186d7a52303310 725 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 459 649 2.4E-46 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS30645 9b7a4a893776d509d2186d7a52303310 725 Gene3D G3DSA:3.30.450.20 193 321 2.0E-13 T 29-03-2018 THSYN_RS30645 9b7a4a893776d509d2186d7a52303310 725 Gene3D G3DSA:3.60.40.10 395 652 6.5E-42 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS05040 3c1c20e8be1e8a14066950b3bcbe6d0e 999 SMART SM00487 285 508 3.0E-5 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS05040 3c1c20e8be1e8a14066950b3bcbe6d0e 999 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 104 223 2.7E-17 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THSYN_RS05040 3c1c20e8be1e8a14066950b3bcbe6d0e 999 SUPERFAMILY SSF52540 250 484 1.9E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05040 3c1c20e8be1e8a14066950b3bcbe6d0e 999 Pfam PF04851 Type III restriction enzyme, res subunit 289 480 1.6E-10 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS05040 3c1c20e8be1e8a14066950b3bcbe6d0e 999 Gene3D G3DSA:3.40.50.300 273 497 1.9E-21 T 29-03-2018 THSYN_RS19290 00e8773db3c96e60717dc379bd4f30b6 125 Gene3D G3DSA:1.10.10.10 13 110 5.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19290 00e8773db3c96e60717dc379bd4f30b6 125 Pfam PF03551 Transcriptional regulator PadR-like family 25 98 1.3E-15 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal THSYN_RS19290 00e8773db3c96e60717dc379bd4f30b6 125 SUPERFAMILY SSF46785 22 114 1.77E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS32845 b056ea7dd91a329c3571343a812b9c88 629 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 5 628 2.0E-184 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like THSYN_RS32845 b056ea7dd91a329c3571343a812b9c88 629 PIRSF PIRSF028304 1 629 1.2E-175 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like THSYN_RS32845 b056ea7dd91a329c3571343a812b9c88 629 Pfam PF05947 Type VI secretion system, TssF 7 627 1.3E-212 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like THSYN_RS13125 87a508869441393b7a0d3d3e17dcd2e9 296 Pfam PF01012 Electron transfer flavoprotein domain 27 194 3.0E-45 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 THSYN_RS13125 87a508869441393b7a0d3d3e17dcd2e9 296 SUPERFAMILY SSF52402 233 288 2.02E-60 T 29-03-2018 THSYN_RS13125 87a508869441393b7a0d3d3e17dcd2e9 296 SUPERFAMILY SSF52402 6 202 2.02E-60 T 29-03-2018 THSYN_RS13125 87a508869441393b7a0d3d3e17dcd2e9 296 Gene3D G3DSA:3.40.50.620 3 295 7.0E-71 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS13125 87a508869441393b7a0d3d3e17dcd2e9 296 PIRSF PIRSF000090 223 295 0.49 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 THSYN_RS13125 87a508869441393b7a0d3d3e17dcd2e9 296 PIRSF PIRSF000090 3 216 2.7E-68 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 THSYN_RS13125 87a508869441393b7a0d3d3e17dcd2e9 296 SMART SM00893 26 211 1.9E-50 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 THSYN_RS10285 8e2ddb8a2accf6c68258ca418d79eb67 159 SUPERFAMILY SSF55718 38 132 2.83E-17 T 29-03-2018 IPR003033 SCP2 sterol-binding domain THSYN_RS10285 8e2ddb8a2accf6c68258ca418d79eb67 159 Pfam PF02036 SCP-2 sterol transfer family 32 127 6.4E-12 T 29-03-2018 IPR003033 SCP2 sterol-binding domain THSYN_RS10285 8e2ddb8a2accf6c68258ca418d79eb67 159 Gene3D G3DSA:3.30.1050.10 13 138 3.6E-14 T 29-03-2018 IPR003033 SCP2 sterol-binding domain THSYN_RS14190 fca9fe4e44ba09c7f5715cab16aa2c31 187 Pfam PF01292 Prokaryotic cytochrome b561 9 179 6.6E-20 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THSYN_RS14190 fca9fe4e44ba09c7f5715cab16aa2c31 187 SUPERFAMILY SSF81342 6 180 3.06E-25 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THSYN_RS14190 fca9fe4e44ba09c7f5715cab16aa2c31 187 Gene3D G3DSA:1.20.950.20 1 187 1.8E-24 T 29-03-2018 THSYN_RS27930 83e479bb2c13704bb92d286e14c9c753 537 Pfam PF13559 Domain of unknown function (DUF4129) 444 511 9.1E-7 T 29-03-2018 IPR025403 Domain of unknown function DUF4129 THSYN_RS15870 93b60ab972806ed20d95383a087ddcf2 87 Pfam PF07007 Lysozyme inhibitor LprI 10 81 1.3E-12 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal THSYN_RS08570 dc7ba0b52b5543000da11d860ad58cdc 318 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 317 3.8E-154 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS08570 dc7ba0b52b5543000da11d860ad58cdc 318 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 148 1.1E-64 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS08570 dc7ba0b52b5543000da11d860ad58cdc 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 2.2E-50 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS08570 dc7ba0b52b5543000da11d860ad58cdc 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 2.2E-50 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS08570 dc7ba0b52b5543000da11d860ad58cdc 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 2.2E-50 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS08570 dc7ba0b52b5543000da11d860ad58cdc 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 2.2E-50 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS08570 dc7ba0b52b5543000da11d860ad58cdc 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 2.2E-50 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS08570 dc7ba0b52b5543000da11d860ad58cdc 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 2.2E-50 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS08570 dc7ba0b52b5543000da11d860ad58cdc 318 Gene3D G3DSA:3.90.226.10 28 297 2.2E-66 T 29-03-2018 THSYN_RS08570 dc7ba0b52b5543000da11d860ad58cdc 318 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 50.862 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 THSYN_RS08570 dc7ba0b52b5543000da11d860ad58cdc 318 SUPERFAMILY SSF52096 5 316 3.32E-102 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS09910 6becbda869ad1dd35f13d791e5cf3a1b 445 Gene3D G3DSA:3.20.20.80 3 445 4.8E-171 T 29-03-2018 THSYN_RS09910 6becbda869ad1dd35f13d791e5cf3a1b 445 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 11 25 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site THSYN_RS09910 6becbda869ad1dd35f13d791e5cf3a1b 445 SUPERFAMILY SSF51445 5 441 1.44E-165 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS09910 6becbda869ad1dd35f13d791e5cf3a1b 445 PRINTS PR00131 Glycosyl hydrolase family 1 signature 285 299 2.6E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 THSYN_RS09910 6becbda869ad1dd35f13d791e5cf3a1b 445 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 380 2.6E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 THSYN_RS09910 6becbda869ad1dd35f13d791e5cf3a1b 445 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 426 2.6E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 THSYN_RS09910 6becbda869ad1dd35f13d791e5cf3a1b 445 PRINTS PR00131 Glycosyl hydrolase family 1 signature 390 407 2.6E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 THSYN_RS09910 6becbda869ad1dd35f13d791e5cf3a1b 445 PRINTS PR00131 Glycosyl hydrolase family 1 signature 348 356 2.6E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 THSYN_RS09910 6becbda869ad1dd35f13d791e5cf3a1b 445 Pfam PF00232 Glycosyl hydrolase family 1 6 442 5.4E-160 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 THSYN_RS09910 6becbda869ad1dd35f13d791e5cf3a1b 445 TIGRFAM TIGR03356 BGL: beta-galactosidase 7 436 2.5E-178 T 29-03-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092 THSYN_RS30420 1f3536543106996ddd4e96910a6c6778 433 Pfam PF03743 Bacterial conjugation TrbI-like protein 226 429 1.9E-34 T 29-03-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI THSYN_RS14625 2270fd4d2bf9864aa75a0c1d8c0f0ba2 491 Gene3D G3DSA:3.20.20.70 118 450 2.0E-41 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS14625 2270fd4d2bf9864aa75a0c1d8c0f0ba2 491 Pfam PF13186 Iron-sulfur cluster-binding domain 377 441 4.7E-10 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain THSYN_RS14625 2270fd4d2bf9864aa75a0c1d8c0f0ba2 491 SUPERFAMILY SSF102114 123 450 1.96E-65 T 29-03-2018 THSYN_RS14625 2270fd4d2bf9864aa75a0c1d8c0f0ba2 491 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 377 457 1.1E-12 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain THSYN_RS14625 2270fd4d2bf9864aa75a0c1d8c0f0ba2 491 Pfam PF04055 Radical SAM superfamily 132 288 1.6E-19 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS14625 2270fd4d2bf9864aa75a0c1d8c0f0ba2 491 Pfam PF13353 4Fe-4S single cluster domain 133 239 2.4E-8 T 29-03-2018 THSYN_RS25535 050f126b47d28c4b6f8a9b189e2064ad 99 Gene3D G3DSA:1.20.5.50 1 98 2.9E-6 T 29-03-2018 THSYN_RS25535 050f126b47d28c4b6f8a9b189e2064ad 99 SUPERFAMILY SSF58113 5 97 1.05E-6 T 29-03-2018 THSYN_RS04910 fab02c634bd0391864a9c9a20e60ebef 145 Gene3D G3DSA:1.10.260.40 88 145 1.0E-5 T 29-03-2018 THSYN_RS04910 fab02c634bd0391864a9c9a20e60ebef 145 Pfam PF10387 Protein of unknown function (DUF2442) 4 77 1.1E-11 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS04910 fab02c634bd0391864a9c9a20e60ebef 145 Gene3D G3DSA:3.30.2020.10 1 80 2.4E-11 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS04910 fab02c634bd0391864a9c9a20e60ebef 145 SUPERFAMILY SSF47413 87 142 5.47E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS04910 fab02c634bd0391864a9c9a20e60ebef 145 SUPERFAMILY SSF143880 2 81 2.75E-12 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS26540 464e3a9da6c3691e6416f520121deb02 142 SUPERFAMILY SSF52821 8 141 3.01E-19 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS26540 464e3a9da6c3691e6416f520121deb02 142 Gene3D G3DSA:3.40.250.10 2 142 9.4E-22 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS26540 464e3a9da6c3691e6416f520121deb02 142 SMART SM00450 10 125 1.5E-10 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS26540 464e3a9da6c3691e6416f520121deb02 142 Pfam PF00581 Rhodanese-like domain 10 118 2.0E-10 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS02855 1ef8dd59aaa0d8d8b8c92ff37ab3bc3b 354 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 25 134 1.1E-9 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS02855 1ef8dd59aaa0d8d8b8c92ff37ab3bc3b 354 SMART SM00382 21 152 0.0023 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS02855 1ef8dd59aaa0d8d8b8c92ff37ab3bc3b 354 SUPERFAMILY SSF52540 19 156 1.4E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02855 1ef8dd59aaa0d8d8b8c92ff37ab3bc3b 354 Gene3D G3DSA:3.40.50.300 6 157 5.5E-17 T 29-03-2018 THSYN_RS17885 06884346961ae4f962ef1a9eaa10e291 639 SUPERFAMILY SSF109998 40 166 1.83E-30 T 29-03-2018 IPR027304 Trigger factor/SurA domain THSYN_RS17885 06884346961ae4f962ef1a9eaa10e291 639 SUPERFAMILY SSF109998 200 240 1.83E-30 T 29-03-2018 IPR027304 Trigger factor/SurA domain THSYN_RS17885 06884346961ae4f962ef1a9eaa10e291 639 Gene3D G3DSA:3.10.50.40 257 393 3.6E-39 T 29-03-2018 THSYN_RS17885 06884346961ae4f962ef1a9eaa10e291 639 Gene3D G3DSA:3.10.50.40 406 503 1.0E-4 T 29-03-2018 THSYN_RS17885 06884346961ae4f962ef1a9eaa10e291 639 Gene3D G3DSA:3.10.50.40 504 598 0.025 T 29-03-2018 THSYN_RS17885 06884346961ae4f962ef1a9eaa10e291 639 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 306 327 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 THSYN_RS17885 06884346961ae4f962ef1a9eaa10e291 639 Pfam PF13624 SurA N-terminal domain 1 162 1.5E-48 T 29-03-2018 THSYN_RS17885 06884346961ae4f962ef1a9eaa10e291 639 Pfam PF00639 PPIC-type PPIASE domain 272 366 2.7E-24 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 THSYN_RS17885 06884346961ae4f962ef1a9eaa10e291 639 SUPERFAMILY SSF54534 262 370 1.11E-28 T 29-03-2018 THSYN_RS17885 06884346961ae4f962ef1a9eaa10e291 639 Gene3D G3DSA:1.10.4030.10 37 169 6.0E-22 T 29-03-2018 THSYN_RS11075 1a3378482b007060de693cdd67d7cd71 92 Pfam PF00953 Glycosyl transferase family 4 49 90 1.5E-6 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 THSYN_RS06515 c0cfaaf862fcfb1521a6a79d71236222 175 Gene3D G3DSA:3.30.1380.10 46 175 1.0E-24 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS06515 c0cfaaf862fcfb1521a6a79d71236222 175 Pfam PF05951 Bacterial protein of unknown function (DUF882) 24 173 4.0E-54 T 29-03-2018 IPR010275 Protein of unknown function DUF882 THSYN_RS06515 c0cfaaf862fcfb1521a6a79d71236222 175 SUPERFAMILY SSF55166 56 174 4.71E-33 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 Gene3D G3DSA:3.30.420.40 145 291 5.1E-17 T 29-03-2018 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 317 1.1E-130 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 335 63.451 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 29-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 SUPERFAMILY SSF53067 3 123 1.68E-28 T 29-03-2018 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 310 5.7E-117 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 4.9E-52 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 4.9E-52 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 4.9E-52 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 4.9E-52 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 4.9E-52 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 4.9E-52 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 SUPERFAMILY SSF53067 101 313 3.42E-43 T 29-03-2018 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 Pfam PF00814 Glycoprotease family 24 311 4.0E-99 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THSYN_RS20990 38106a201e32cf519403992602d072fd 344 Gene3D G3DSA:3.30.420.40 1 144 4.0E-40 T 29-03-2018 THSYN_RS30035 74a9fe3943137a42ad0a37fd6665d00c 147 Gene3D G3DSA:1.10.10.60 10 34 1.2E-9 T 29-03-2018 THSYN_RS30035 74a9fe3943137a42ad0a37fd6665d00c 147 SUPERFAMILY SSF47413 9 75 1.98E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS30035 74a9fe3943137a42ad0a37fd6665d00c 147 Pfam PF01381 Helix-turn-helix 14 68 1.2E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS30035 74a9fe3943137a42ad0a37fd6665d00c 147 SMART SM00530 13 68 2.4E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS30035 74a9fe3943137a42ad0a37fd6665d00c 147 Gene3D G3DSA:3.30.1190.10 35 94 8.0E-11 T 29-03-2018 THSYN_RS24710 340eb98ac417865513deab4dbf826e6e 1062 Pfam PF00271 Helicase conserved C-terminal domain 618 728 5.9E-20 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS24710 340eb98ac417865513deab4dbf826e6e 1062 SMART SM00490 646 728 1.2E-24 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS24710 340eb98ac417865513deab4dbf826e6e 1062 Gene3D G3DSA:3.40.50.10810 327 535 6.2E-40 T 29-03-2018 THSYN_RS24710 340eb98ac417865513deab4dbf826e6e 1062 SUPERFAMILY SSF52540 606 766 2.18E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24710 340eb98ac417865513deab4dbf826e6e 1062 SUPERFAMILY SSF52540 437 477 2.18E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24710 340eb98ac417865513deab4dbf826e6e 1062 Pfam PF04434 SWIM zinc finger 87 108 0.3 T 29-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 THSYN_RS24710 340eb98ac417865513deab4dbf826e6e 1062 Pfam PF04434 SWIM zinc finger 179 203 0.011 T 29-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 THSYN_RS24710 340eb98ac417865513deab4dbf826e6e 1062 SMART SM00487 322 503 2.7E-27 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS24710 340eb98ac417865513deab4dbf826e6e 1062 Pfam PF00176 SNF2 family N-terminal domain 344 604 7.5E-37 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THSYN_RS24710 340eb98ac417865513deab4dbf826e6e 1062 SUPERFAMILY SSF52540 322 534 2.15E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24710 340eb98ac417865513deab4dbf826e6e 1062 Gene3D G3DSA:3.40.50.300 607 766 1.8E-35 T 29-03-2018 THSYN_RS31830 0bccb7657e69d760d5a6ce858050b93e 555 Pfam PF07969 Amidohydrolase family 44 486 2.4E-54 T 29-03-2018 IPR013108 Amidohydrolase 3 THSYN_RS31830 0bccb7657e69d760d5a6ce858050b93e 555 Gene3D G3DSA:2.30.40.10 2 57 5.7E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS31830 0bccb7657e69d760d5a6ce858050b93e 555 PIRSF PIRSF006453 1 548 6.7E-231 T 29-03-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A THSYN_RS31830 0bccb7657e69d760d5a6ce858050b93e 555 SUPERFAMILY SSF51338 422 507 3.6E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS31830 0bccb7657e69d760d5a6ce858050b93e 555 Gene3D G3DSA:2.30.40.10 395 490 5.7E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS31830 0bccb7657e69d760d5a6ce858050b93e 555 SUPERFAMILY SSF51338 4 66 1.57E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THSYN_RS31830 0bccb7657e69d760d5a6ce858050b93e 555 TIGRFAM TIGR03121 one_C_dehyd_A: formylmethanofuran dehydrogenase subunit A 3 537 1.5E-228 T 29-03-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A THSYN_RS31830 0bccb7657e69d760d5a6ce858050b93e 555 SUPERFAMILY SSF51556 54 449 3.79E-28 T 29-03-2018 IPR032466 Metal-dependent hydrolase THSYN_RS31830 0bccb7657e69d760d5a6ce858050b93e 555 Gene3D G3DSA:3.20.20.140 58 327 2.3E-10 T 29-03-2018 THSYN_RS32535 06432ee6dab1c5f67b6306aa20b43ccf 351 SUPERFAMILY SSF53474 50 327 5.09E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS32535 06432ee6dab1c5f67b6306aa20b43ccf 351 PRINTS PR00111 Alpha/beta hydrolase fold signature 165 178 4.0E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS32535 06432ee6dab1c5f67b6306aa20b43ccf 351 PRINTS PR00111 Alpha/beta hydrolase fold signature 151 164 4.0E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS32535 06432ee6dab1c5f67b6306aa20b43ccf 351 PRINTS PR00111 Alpha/beta hydrolase fold signature 272 286 4.0E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS32535 06432ee6dab1c5f67b6306aa20b43ccf 351 Gene3D G3DSA:3.40.50.1820 34 329 7.3E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS32535 06432ee6dab1c5f67b6306aa20b43ccf 351 PRINTS PR00412 Epoxide hydrolase signature 303 325 2.9E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS32535 06432ee6dab1c5f67b6306aa20b43ccf 351 PRINTS PR00412 Epoxide hydrolase signature 81 99 2.9E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS32535 06432ee6dab1c5f67b6306aa20b43ccf 351 PRINTS PR00412 Epoxide hydrolase signature 270 286 2.9E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS32535 06432ee6dab1c5f67b6306aa20b43ccf 351 PRINTS PR00412 Epoxide hydrolase signature 165 178 2.9E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 THSYN_RS32535 06432ee6dab1c5f67b6306aa20b43ccf 351 Pfam PF12146 Serine aminopeptidase, S33 74 312 1.4E-24 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 THSYN_RS30030 a607dd87871bd9ad97187ed23ee7efa5 396 Pfam PF09992 Phosphodiester glycosidase 205 388 3.3E-31 T 29-03-2018 IPR018711 Phosphodiester glycosidase THSYN_RS01995 e3b7e29ce14bd98fb1d37506913e2b80 206 Pfam PF05685 Putative restriction endonuclease 20 188 8.3E-32 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS01995 e3b7e29ce14bd98fb1d37506913e2b80 206 Gene3D G3DSA:3.90.1570.10 6 194 1.7E-41 T 29-03-2018 THSYN_RS01995 e3b7e29ce14bd98fb1d37506913e2b80 206 SUPERFAMILY SSF52980 12 194 2.79E-36 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS31620 3eb8c03913d510d1fd11f628265f5b9f 115 SUPERFAMILY SSF46689 16 75 5.55E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS31620 3eb8c03913d510d1fd11f628265f5b9f 115 Pfam PF04255 Protein of unknown function (DUF433) 17 64 4.1E-9 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS31620 3eb8c03913d510d1fd11f628265f5b9f 115 Gene3D G3DSA:1.10.10.10 14 72 1.0E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS01575 83ad82bbca1777ce83d5b0126cc5e1ac 489 SUPERFAMILY SSF53335 7 484 5.12E-123 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS01575 83ad82bbca1777ce83d5b0126cc5e1ac 489 Gene3D G3DSA:3.40.50.150 142 442 2.3E-49 T 29-03-2018 THSYN_RS01575 83ad82bbca1777ce83d5b0126cc5e1ac 489 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 168 182 5.2E-20 T 29-03-2018 THSYN_RS01575 83ad82bbca1777ce83d5b0126cc5e1ac 489 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 144 160 5.2E-20 T 29-03-2018 THSYN_RS01575 83ad82bbca1777ce83d5b0126cc5e1ac 489 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 255 267 5.2E-20 T 29-03-2018 THSYN_RS01575 83ad82bbca1777ce83d5b0126cc5e1ac 489 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 284 308 5.2E-20 T 29-03-2018 THSYN_RS01575 83ad82bbca1777ce83d5b0126cc5e1ac 489 Pfam PF12161 HsdM N-terminal domain 9 110 6.1E-7 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS01575 83ad82bbca1777ce83d5b0126cc5e1ac 489 Pfam PF02384 N-6 DNA Methylase 122 432 5.4E-71 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS30845 a18be84e0eaf68b7dc5f807766a0708e 74 SUPERFAMILY SSF47598 5 44 8.15E-6 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS30845 a18be84e0eaf68b7dc5f807766a0708e 74 Gene3D G3DSA:1.10.1220.10 4 46 2.1E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS24515 21bc74f5da49a4ced20094e460bfc57b 138 PRINTS PR01438 Universal stress protein signature 95 107 1.3E-14 T 29-03-2018 IPR006015 Universal stress protein A THSYN_RS24515 21bc74f5da49a4ced20094e460bfc57b 138 PRINTS PR01438 Universal stress protein signature 1 17 1.3E-14 T 29-03-2018 IPR006015 Universal stress protein A THSYN_RS24515 21bc74f5da49a4ced20094e460bfc57b 138 PRINTS PR01438 Universal stress protein signature 113 135 1.3E-14 T 29-03-2018 IPR006015 Universal stress protein A THSYN_RS24515 21bc74f5da49a4ced20094e460bfc57b 138 SUPERFAMILY SSF52402 3 137 1.67E-37 T 29-03-2018 THSYN_RS24515 21bc74f5da49a4ced20094e460bfc57b 138 Pfam PF00582 Universal stress protein family 3 135 6.2E-33 T 29-03-2018 IPR006016 UspA GO:0006950 THSYN_RS24515 21bc74f5da49a4ced20094e460bfc57b 138 Gene3D G3DSA:3.40.50.620 1 138 4.0E-38 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS01145 cfb8044570926a2c9760db9c6a393bd2 151 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 135 2.9E-38 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 THSYN_RS01145 cfb8044570926a2c9760db9c6a393bd2 151 SUPERFAMILY SSF102400 1 140 1.44E-41 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 THSYN_RS01145 cfb8044570926a2c9760db9c6a393bd2 151 Gene3D G3DSA:3.40.50.10110 1 142 7.8E-45 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 THSYN_RS15820 7e622eb9fbb5eee39365683193ba6e15 605 SUPERFAMILY SSF48208 216 602 5.1E-88 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 THSYN_RS15820 7e622eb9fbb5eee39365683193ba6e15 605 Gene3D G3DSA:1.50.10.10 199 556 2.3E-82 T 29-03-2018 THSYN_RS15820 7e622eb9fbb5eee39365683193ba6e15 605 Pfam PF00723 Glycosyl hydrolases family 15 231 540 5.3E-25 T 29-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 THSYN_RS32645 89351165d626479d1b3d18cc95f825ac 101 TIGRFAM TIGR03859 PQQ_PqqD: coenzyme PQQ biosynthesis protein PqqD 17 97 1.6E-32 T 29-03-2018 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 THSYN_RS32645 89351165d626479d1b3d18cc95f825ac 101 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 35 96 1.1E-13 T 29-03-2018 IPR008792 Coenzyme PQQ synthesis D THSYN_RS32645 89351165d626479d1b3d18cc95f825ac 101 Hamap MF_00655 Coenzyme PQQ synthesis protein D [pqqD]. 11 98 22.052 T 29-03-2018 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 THSYN_RS27005 394a8fbc711891f9a556278edee847d0 352 SUPERFAMILY SSF75005 24 276 9.42E-26 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain THSYN_RS27005 394a8fbc711891f9a556278edee847d0 352 SUPERFAMILY SSF75005 238 350 1.01E-11 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain THSYN_RS27005 394a8fbc711891f9a556278edee847d0 352 Gene3D G3DSA:2.115.10.20 213 282 4.4E-14 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain THSYN_RS27005 394a8fbc711891f9a556278edee847d0 352 Gene3D G3DSA:2.115.10.20 283 352 4.0E-7 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain THSYN_RS27005 394a8fbc711891f9a556278edee847d0 352 Gene3D G3DSA:2.115.10.20 2 84 1.7E-7 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain THSYN_RS27005 394a8fbc711891f9a556278edee847d0 352 Gene3D G3DSA:2.115.10.20 85 212 1.6E-15 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain THSYN_RS27890 8c4812644c7e0a5da80c0e9dc626a784 307 Gene3D G3DSA:1.10.10.10 1 92 5.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS27890 8c4812644c7e0a5da80c0e9dc626a784 307 Pfam PF03466 LysR substrate binding domain 90 294 3.8E-44 T 29-03-2018 IPR005119 LysR, substrate-binding THSYN_RS27890 8c4812644c7e0a5da80c0e9dc626a784 307 Gene3D G3DSA:3.40.190.10 93 183 9.0E-25 T 29-03-2018 THSYN_RS27890 8c4812644c7e0a5da80c0e9dc626a784 307 SUPERFAMILY SSF53850 88 298 1.03E-44 T 29-03-2018 THSYN_RS27890 8c4812644c7e0a5da80c0e9dc626a784 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS27890 8c4812644c7e0a5da80c0e9dc626a784 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS27890 8c4812644c7e0a5da80c0e9dc626a784 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS27890 8c4812644c7e0a5da80c0e9dc626a784 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 1.0E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS27890 8c4812644c7e0a5da80c0e9dc626a784 307 Gene3D G3DSA:3.40.190.10 184 266 8.5E-15 T 29-03-2018 THSYN_RS27890 8c4812644c7e0a5da80c0e9dc626a784 307 SUPERFAMILY SSF46785 1 113 2.59E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS03580 349288b81b50f15e7c4760332f0f10b5 411 Pfam PF02491 SHS2 domain inserted in FTSA 85 162 3.1E-30 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 THSYN_RS03580 349288b81b50f15e7c4760332f0f10b5 411 SUPERFAMILY SSF53067 199 378 1.17E-48 T 29-03-2018 THSYN_RS03580 349288b81b50f15e7c4760332f0f10b5 411 Gene3D G3DSA:3.30.420.40 266 352 2.6E-20 T 29-03-2018 THSYN_RS03580 349288b81b50f15e7c4760332f0f10b5 411 Gene3D G3DSA:3.30.420.40 197 265 2.5E-8 T 29-03-2018 THSYN_RS03580 349288b81b50f15e7c4760332f0f10b5 411 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 411 30.885 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 THSYN_RS03580 349288b81b50f15e7c4760332f0f10b5 411 Gene3D G3DSA:3.30.420.40 2 188 3.6E-39 T 29-03-2018 THSYN_RS03580 349288b81b50f15e7c4760332f0f10b5 411 SMART SM00842 10 196 3.3E-101 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 THSYN_RS03580 349288b81b50f15e7c4760332f0f10b5 411 SUPERFAMILY SSF53067 9 197 7.66E-58 T 29-03-2018 THSYN_RS03580 349288b81b50f15e7c4760332f0f10b5 411 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 10 378 3.1E-147 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 THSYN_RS03580 349288b81b50f15e7c4760332f0f10b5 411 PIRSF PIRSF003101 1 411 1.1E-153 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 THSYN_RS03580 349288b81b50f15e7c4760332f0f10b5 411 Pfam PF14450 Cell division protein FtsA 11 185 2.5E-12 T 29-03-2018 THSYN_RS03580 349288b81b50f15e7c4760332f0f10b5 411 Pfam PF14450 Cell division protein FtsA 207 374 1.2E-26 T 29-03-2018 THSYN_RS26585 0efbc302fa185eebd7e4441bfa50cfdc 273 Gene3D G3DSA:2.160.10.10 61 234 7.0E-40 T 29-03-2018 THSYN_RS26585 0efbc302fa185eebd7e4441bfa50cfdc 273 Gene3D G3DSA:1.10.3130.10 1 60 1.6E-25 T 29-03-2018 THSYN_RS26585 0efbc302fa185eebd7e4441bfa50cfdc 273 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 166 2.2E-76 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 THSYN_RS26585 0efbc302fa185eebd7e4441bfa50cfdc 273 PIRSF PIRSF000441 1 234 3.9E-87 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 THSYN_RS26585 0efbc302fa185eebd7e4441bfa50cfdc 273 SUPERFAMILY SSF51161 3 171 4.02E-55 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS26585 0efbc302fa185eebd7e4441bfa50cfdc 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 THSYN_RS26585 0efbc302fa185eebd7e4441bfa50cfdc 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 83 108 4.8E-4 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS26585 0efbc302fa185eebd7e4441bfa50cfdc 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 150 4.3E-7 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS18090 05b902155bdc35c4b73f8d8717e61c2a 840 Gene3D G3DSA:1.10.10.10 779 836 4.0E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS18090 05b902155bdc35c4b73f8d8717e61c2a 840 Gene3D G3DSA:3.90.220.10 73 237 3.3E-5 T 29-03-2018 THSYN_RS27340 c2f52630a066ff2c4f42faa6f8fe131b 88 Gene3D G3DSA:1.10.1220.10 8 85 2.2E-7 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS27340 c2f52630a066ff2c4f42faa6f8fe131b 88 SUPERFAMILY SSF47598 8 48 2.67E-5 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS01315 ae61d8d6657d24ca285b21c82e5885a5 401 Pfam PF07007 Lysozyme inhibitor LprI 29 107 1.5E-5 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal THSYN_RS28850 75b44452896bf7d913e87374d5d31063 153 Pfam PF00364 Biotin-requiring enzyme 79 152 4.0E-21 T 29-03-2018 IPR000089 Biotin/lipoyl attachment THSYN_RS28850 75b44452896bf7d913e87374d5d31063 153 Gene3D G3DSA:2.40.50.100 4 153 3.5E-19 T 29-03-2018 THSYN_RS28850 75b44452896bf7d913e87374d5d31063 153 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 153 9.2E-52 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 THSYN_RS28850 75b44452896bf7d913e87374d5d31063 153 SUPERFAMILY SSF51230 79 153 3.66E-23 T 29-03-2018 IPR011053 Single hybrid motif THSYN_RS28850 75b44452896bf7d913e87374d5d31063 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 114 127 1.1E-16 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 THSYN_RS28850 75b44452896bf7d913e87374d5d31063 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 99 113 1.1E-16 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 THSYN_RS28850 75b44452896bf7d913e87374d5d31063 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 82 95 1.1E-16 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 THSYN_RS09235 f65601ec35e734a11d949163b8bcd076 191 SUPERFAMILY SSF50978 15 159 7.14E-15 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 THSYN_RS09235 f65601ec35e734a11d949163b8bcd076 191 Pfam PF00400 WD domain, G-beta repeat 100 126 0.012 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09235 f65601ec35e734a11d949163b8bcd076 191 SMART SM00320 79 127 0.0068 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09235 f65601ec35e734a11d949163b8bcd076 191 SMART SM00320 37 76 0.8 T 29-03-2018 IPR001680 WD40 repeat GO:0005515 THSYN_RS09235 f65601ec35e734a11d949163b8bcd076 191 Gene3D G3DSA:2.120.10.60 1 189 7.6E-17 T 29-03-2018 THSYN_RS25060 1509b3916234adfbc93345bd22494d22 316 Gene3D G3DSA:3.40.50.150 18 302 1.6E-30 T 29-03-2018 THSYN_RS25060 1509b3916234adfbc93345bd22494d22 316 Pfam PF08241 Methyltransferase domain 99 191 1.4E-20 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THSYN_RS25060 1509b3916234adfbc93345bd22494d22 316 SUPERFAMILY SSF53335 29 259 2.13E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS21750 f6b9f689ce47c2017feb1382d5780d09 100 Gene3D G3DSA:3.30.2310.20 2 91 3.1E-6 T 29-03-2018 THSYN_RS21750 f6b9f689ce47c2017feb1382d5780d09 100 PIRSF PIRSF029218 1 99 3.5E-29 T 29-03-2018 IPR028344 Toxin-antitoxin system, toxin component ParE1/4 THSYN_RS21750 f6b9f689ce47c2017feb1382d5780d09 100 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 92 4.2E-21 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS22770 82e5e1f46e2cd905bed0b9499bfbbe52 302 SUPERFAMILY SSF53448 3 224 6.84E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22770 82e5e1f46e2cd905bed0b9499bfbbe52 302 Gene3D G3DSA:3.90.550.10 1 287 4.9E-56 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22770 82e5e1f46e2cd905bed0b9499bfbbe52 302 Pfam PF00535 Glycosyl transferase family 2 6 126 2.0E-33 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS24895 ffd094ac08571553074bf6db8d460444 205 ProSitePatterns PS00856 Guanylate kinase-like signature. 38 55 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 THSYN_RS24895 ffd094ac08571553074bf6db8d460444 205 Pfam PF00625 Guanylate kinase 6 182 1.6E-47 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit THSYN_RS24895 ffd094ac08571553074bf6db8d460444 205 Gene3D G3DSA:3.40.50.300 1 47 3.8E-5 T 29-03-2018 THSYN_RS24895 ffd094ac08571553074bf6db8d460444 205 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 181 1.1E-67 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 THSYN_RS24895 ffd094ac08571553074bf6db8d460444 205 SMART SM00072 3 185 2.8E-66 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit THSYN_RS24895 ffd094ac08571553074bf6db8d460444 205 Hamap MF_00328 Guanylate kinase [gmk]. 2 185 35.083 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 THSYN_RS24895 ffd094ac08571553074bf6db8d460444 205 SUPERFAMILY SSF52540 3 187 3.51E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24895 ffd094ac08571553074bf6db8d460444 205 Gene3D G3DSA:3.40.50.300 80 186 2.7E-29 T 29-03-2018 THSYN_RS24895 ffd094ac08571553074bf6db8d460444 205 Gene3D G3DSA:3.30.63.10 48 79 7.5E-21 T 29-03-2018 THSYN_RS09405 615f671f6a108db67b3e9aadf476f28d 160 SMART SM00100 15 132 3.1E-4 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS09405 615f671f6a108db67b3e9aadf476f28d 160 SUPERFAMILY SSF51206 17 136 3.27E-21 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like THSYN_RS09405 615f671f6a108db67b3e9aadf476f28d 160 Gene3D G3DSA:2.60.120.10 5 156 3.4E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS09405 615f671f6a108db67b3e9aadf476f28d 160 Pfam PF00027 Cyclic nucleotide-binding domain 35 120 2.6E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain THSYN_RS22900 8e371ff85f267827bf0d69427e5975f8 108 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 4 100 2.6E-44 T 29-03-2018 IPR004480 Monothiol glutaredoxin-related THSYN_RS22900 8e371ff85f267827bf0d69427e5975f8 108 Pfam PF00462 Glutaredoxin 16 80 2.3E-20 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 THSYN_RS22900 8e371ff85f267827bf0d69427e5975f8 108 PIRSF PIRSF005894 1 107 1.8E-47 T 29-03-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 THSYN_RS22900 8e371ff85f267827bf0d69427e5975f8 108 SUPERFAMILY SSF52833 1 102 2.08E-37 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS22900 8e371ff85f267827bf0d69427e5975f8 108 Gene3D G3DSA:3.40.30.10 1 108 2.7E-34 T 29-03-2018 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 Gene3D G3DSA:2.60.34.10 341 582 2.8E-43 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 PRINTS PR00301 70kDa heat shock protein signature 4 17 1.8E-46 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.8E-46 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 PRINTS PR00301 70kDa heat shock protein signature 173 183 1.8E-46 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 PRINTS PR00301 70kDa heat shock protein signature 335 355 1.8E-46 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.8E-46 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 PRINTS PR00301 70kDa heat shock protein signature 114 134 1.8E-46 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 PRINTS PR00301 70kDa heat shock protein signature 358 377 1.8E-46 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 PRINTS PR00301 70kDa heat shock protein signature 446 462 1.8E-46 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 PRINTS PR00301 70kDa heat shock protein signature 304 320 1.8E-46 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 SUPERFAMILY SSF53067 162 351 1.91E-52 T 29-03-2018 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 Pfam PF00012 Hsp70 protein 5 77 1.8E-16 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 Pfam PF00012 Hsp70 protein 78 586 2.6E-122 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 SUPERFAMILY SSF100920 360 494 1.57E-31 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 Gene3D G3DSA:3.90.640.10 211 272 1.6E-18 T 29-03-2018 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 Gene3D G3DSA:3.30.420.40 3 166 3.2E-57 T 29-03-2018 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 SUPERFAMILY SSF53067 4 159 4.63E-51 T 29-03-2018 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 8 15 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 Gene3D G3DSA:3.30.420.40 273 332 9.3E-10 T 29-03-2018 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 Gene3D G3DSA:3.30.420.40 167 210 5.3E-16 T 29-03-2018 THSYN_RS18745 123e3a844343bdbcd99d595d8329feba 595 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 167 180 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THSYN_RS07465 e4b4080dd1205cca9a468b44679bc102 175 Pfam PF10986 Protein of unknown function (DUF2796) 34 109 1.5E-11 T 29-03-2018 IPR021253 Protein of unknown function DUF2796 THSYN_RS07465 e4b4080dd1205cca9a468b44679bc102 175 Pfam PF10986 Protein of unknown function (DUF2796) 115 167 2.5E-6 T 29-03-2018 IPR021253 Protein of unknown function DUF2796 THSYN_RS07805 3ea34f5072692552824645444f0f52ae 323 Gene3D G3DSA:1.10.220.30 235 320 0.0016 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical THSYN_RS12640 ecfe5bb0993f38fc3a5c5c29860def9f 812 Pfam PF03772 Competence protein 239 506 9.2E-62 T 29-03-2018 IPR004477 ComEC/Rec2-related protein THSYN_RS12640 ecfe5bb0993f38fc3a5c5c29860def9f 812 Pfam PF13567 Domain of unknown function (DUF4131) 42 196 6.2E-29 T 29-03-2018 IPR025405 Domain of unknown function DUF4131 THSYN_RS12640 ecfe5bb0993f38fc3a5c5c29860def9f 812 SMART SM00849 543 734 4.8E-8 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS12640 ecfe5bb0993f38fc3a5c5c29860def9f 812 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 136 763 4.3E-102 T 29-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 THSYN_RS12640 ecfe5bb0993f38fc3a5c5c29860def9f 812 Gene3D G3DSA:3.60.15.10 536 771 3.8E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS12640 ecfe5bb0993f38fc3a5c5c29860def9f 812 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 260 439 5.5E-26 T 29-03-2018 IPR004477 ComEC/Rec2-related protein THSYN_RS12640 ecfe5bb0993f38fc3a5c5c29860def9f 812 Pfam PF00753 Metallo-beta-lactamase superfamily 540 723 1.1E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS12640 ecfe5bb0993f38fc3a5c5c29860def9f 812 SUPERFAMILY SSF56281 531 767 2.29E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS01955 7a1e1c594495d9e3c02c3d590ee9619a 708 Pfam PF13185 GAF domain 341 468 3.3E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS01955 7a1e1c594495d9e3c02c3d590ee9619a 708 TIGRFAM TIGR02916 PEP_his_kin: putative PEP-CTERM system histidine kinase 17 693 4.8E-240 T 29-03-2018 IPR014265 Signal transduction histidine kinase, PEP-CTERM system, putative THSYN_RS01955 7a1e1c594495d9e3c02c3d590ee9619a 708 Gene3D G3DSA:3.30.565.10 497 695 2.3E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01955 7a1e1c594495d9e3c02c3d590ee9619a 708 PRINTS PR00344 Bacterial sensor protein C-terminal signature 656 674 1.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01955 7a1e1c594495d9e3c02c3d590ee9619a 708 PRINTS PR00344 Bacterial sensor protein C-terminal signature 644 654 1.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01955 7a1e1c594495d9e3c02c3d590ee9619a 708 PRINTS PR00344 Bacterial sensor protein C-terminal signature 625 639 1.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01955 7a1e1c594495d9e3c02c3d590ee9619a 708 PRINTS PR00344 Bacterial sensor protein C-terminal signature 680 693 1.3E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THSYN_RS01955 7a1e1c594495d9e3c02c3d590ee9619a 708 SUPERFAMILY SSF55874 554 694 9.43E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01955 7a1e1c594495d9e3c02c3d590ee9619a 708 SUPERFAMILY SSF55781 337 469 8.51E-11 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS01955 7a1e1c594495d9e3c02c3d590ee9619a 708 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 589 694 2.3E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS01955 7a1e1c594495d9e3c02c3d590ee9619a 708 Gene3D G3DSA:3.30.450.40 315 484 1.1E-9 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS01955 7a1e1c594495d9e3c02c3d590ee9619a 708 SMART SM00387 588 696 1.4E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS16965 b3b2c6cf2f36724e0bc34804635fed32 69 Gene3D G3DSA:3.30.70.100 1 69 3.7E-22 T 29-03-2018 THSYN_RS16965 b3b2c6cf2f36724e0bc34804635fed32 69 Pfam PF00403 Heavy-metal-associated domain 4 62 8.6E-17 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THSYN_RS16965 b3b2c6cf2f36724e0bc34804635fed32 69 SUPERFAMILY SSF55008 1 64 5.11E-19 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THSYN_RS16965 b3b2c6cf2f36724e0bc34804635fed32 69 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 THSYN_RS27300 283599dbee69f290a376fdf855779845 257 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 257 107.522 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THSYN_RS27300 283599dbee69f290a376fdf855779845 257 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 224 4.5E-89 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THSYN_RS27300 283599dbee69f290a376fdf855779845 257 SUPERFAMILY SSF75217 1 242 6.54E-94 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases THSYN_RS27300 283599dbee69f290a376fdf855779845 257 Gene3D G3DSA:1.10.1270.20 169 249 9.7E-29 T 29-03-2018 THSYN_RS27300 283599dbee69f290a376fdf855779845 257 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 220 3.2E-58 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THSYN_RS27300 283599dbee69f290a376fdf855779845 257 Gene3D G3DSA:3.40.1280.10 1 168 2.1E-69 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THSYN_RS27300 283599dbee69f290a376fdf855779845 257 PIRSF PIRSF000386 1 248 1.2E-89 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THSYN_RS24945 09425abdca8a12828e0cf25bf4e47f50 106 SUPERFAMILY SSF50118 2 104 1.62E-31 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS24945 09425abdca8a12828e0cf25bf4e47f50 106 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 103 1.5E-23 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS24945 09425abdca8a12828e0cf25bf4e47f50 106 Gene3D G3DSA:2.30.30.110 1 105 3.8E-25 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 PIRSF PIRSF001174 2 782 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 Gene3D G3DSA:3.30.230.10 584 789 9.3E-69 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 SUPERFAMILY SSF88697 16 208 9.69E-50 T 29-03-2018 IPR015947 PUA-like domain THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 Gene3D G3DSA:3.40.50.300 217 511 1.2E-30 T 29-03-2018 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 Gene3D G3DSA:1.10.8.60 512 583 1.3E-33 T 29-03-2018 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 SUPERFAMILY SSF52540 320 593 3.52E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 577 779 1.4E-96 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 683 691 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 SMART SM00382 355 499 1.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 680 699 6.5E-56 T 29-03-2018 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 602 618 6.5E-56 T 29-03-2018 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 733 751 6.5E-56 T 29-03-2018 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 710 729 6.5E-56 T 29-03-2018 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 363 382 6.5E-56 T 29-03-2018 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 Gene3D G3DSA:1.10.4060.10 129 216 1.4E-28 T 29-03-2018 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 TIGRFAM TIGR00763 lon: endopeptidase La 18 778 2.2E-296 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 SUPERFAMILY SSF54211 602 777 2.54E-59 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 Gene3D G3DSA:2.30.130.40 1 124 1.0E-29 T 29-03-2018 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 Hamap MF_01973 Lon protease [lon]. 17 779 70.821 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 SMART SM00464 16 209 6.6E-74 T 29-03-2018 IPR003111 Lon, substrate-binding domain THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 16 208 6.1E-38 T 29-03-2018 IPR003111 Lon, substrate-binding domain THSYN_RS17905 d0a78586cd0cdbbdcd31b5dfd545e269 818 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 359 496 1.8E-18 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS30495 625e917fd7346f95091ba0c8ec196b87 181 SUPERFAMILY SSF160930 21 175 3.4E-26 T 29-03-2018 THSYN_RS30495 625e917fd7346f95091ba0c8ec196b87 181 Pfam PF05280 Flagellar transcriptional activator (FlhC) 19 180 7.8E-19 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 THSYN_RS30495 625e917fd7346f95091ba0c8ec196b87 181 ProDom PD016592 ACTIVATOR TRANSCRIPTIONAL FLAGELLUM FLAGELLAR TRANSCRIPTION FLHC RNA DNA-BINDING REGULATION DNA-DIRECTED 19 180 5.0E-9 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 THSYN_RS28750 03310d6444ae239f9c85f107ed6db26b 158 SUPERFAMILY SSF54690 3 149 1.44E-51 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THSYN_RS28750 03310d6444ae239f9c85f107ed6db26b 158 Gene3D G3DSA:3.90.1170.40 1 149 4.4E-57 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THSYN_RS28750 03310d6444ae239f9c85f107ed6db26b 158 Pfam PF02391 MoaE protein 7 120 2.9E-37 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THSYN_RS00195 bc84047eb7c576973f243cadcf34066e 362 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 6 352 1.1E-187 T 29-03-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme THSYN_RS00195 bc84047eb7c576973f243cadcf34066e 362 PIRSF PIRSF004869 1 314 2.2E-90 T 29-03-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted THSYN_RS00195 bc84047eb7c576973f243cadcf34066e 362 Pfam PF04055 Radical SAM superfamily 81 230 9.6E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS00195 bc84047eb7c576973f243cadcf34066e 362 Gene3D G3DSA:3.20.20.70 60 321 2.7E-23 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS00195 bc84047eb7c576973f243cadcf34066e 362 SUPERFAMILY SSF102114 51 316 1.06E-38 T 29-03-2018 THSYN_RS19120 6ef0f1a3976f5b5c3cff59a57d35fd1a 109 Gene3D G3DSA:3.30.460.10 2 105 6.8E-17 T 29-03-2018 THSYN_RS19120 6ef0f1a3976f5b5c3cff59a57d35fd1a 109 SUPERFAMILY SSF81301 6 106 6.98E-18 T 29-03-2018 THSYN_RS19120 6ef0f1a3976f5b5c3cff59a57d35fd1a 109 Pfam PF01909 Nucleotidyltransferase domain 19 85 1.3E-10 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS04505 8abb14bc8b30a470ba2e122083f05d1e 485 Pfam PF12161 HsdM N-terminal domain 6 129 1.9E-12 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS04505 8abb14bc8b30a470ba2e122083f05d1e 485 SUPERFAMILY SSF53335 5 479 1.69E-114 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS04505 8abb14bc8b30a470ba2e122083f05d1e 485 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 270 276 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS04505 8abb14bc8b30a470ba2e122083f05d1e 485 Pfam PF02384 N-6 DNA Methylase 139 446 2.2E-72 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS04505 8abb14bc8b30a470ba2e122083f05d1e 485 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 267 279 6.1E-22 T 29-03-2018 THSYN_RS04505 8abb14bc8b30a470ba2e122083f05d1e 485 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 161 177 6.1E-22 T 29-03-2018 THSYN_RS04505 8abb14bc8b30a470ba2e122083f05d1e 485 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 185 199 6.1E-22 T 29-03-2018 THSYN_RS04505 8abb14bc8b30a470ba2e122083f05d1e 485 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 296 320 6.1E-22 T 29-03-2018 THSYN_RS04505 8abb14bc8b30a470ba2e122083f05d1e 485 Gene3D G3DSA:3.40.50.150 159 444 1.3E-51 T 29-03-2018 THSYN_RS26410 9af338843f7be4e257cdca41330625e1 145 SUPERFAMILY SSF52161 7 144 1.3E-57 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THSYN_RS26410 9af338843f7be4e257cdca41330625e1 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 142 2.9E-60 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS26410 9af338843f7be4e257cdca41330625e1 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 142 26.756 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THSYN_RS26410 9af338843f7be4e257cdca41330625e1 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 29-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 THSYN_RS26410 9af338843f7be4e257cdca41330625e1 145 PIRSF PIRSF002181 1 144 1.2E-44 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THSYN_RS26410 9af338843f7be4e257cdca41330625e1 145 Gene3D G3DSA:3.90.1180.10 1 145 5.8E-59 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THSYN_RS26410 9af338843f7be4e257cdca41330625e1 145 Pfam PF00572 Ribosomal protein L13 16 139 1.6E-53 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THSYN_RS03830 5c3d9ec79b59e554fa0c180152c3f610 404 Pfam PF01593 Flavin containing amine oxidoreductase 14 153 3.6E-13 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THSYN_RS03830 5c3d9ec79b59e554fa0c180152c3f610 404 Pfam PF01593 Flavin containing amine oxidoreductase 178 273 1.8E-6 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THSYN_RS03830 5c3d9ec79b59e554fa0c180152c3f610 404 Gene3D G3DSA:3.90.660.20 44 403 1.9E-22 T 29-03-2018 THSYN_RS03830 5c3d9ec79b59e554fa0c180152c3f610 404 Gene3D G3DSA:3.50.50.60 4 43 0.001 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03830 5c3d9ec79b59e554fa0c180152c3f610 404 SUPERFAMILY SSF51905 364 395 3.56E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03830 5c3d9ec79b59e554fa0c180152c3f610 404 SUPERFAMILY SSF51905 8 275 3.56E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS12105 ae256a27bcaf92692ec3fda6bcedf7ac 368 SMART SM00332 1 251 4.5E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS12105 ae256a27bcaf92692ec3fda6bcedf7ac 368 SUPERFAMILY SSF81606 3 251 7.72E-43 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS12105 ae256a27bcaf92692ec3fda6bcedf7ac 368 Gene3D G3DSA:3.60.40.10 3 252 1.9E-30 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS12105 ae256a27bcaf92692ec3fda6bcedf7ac 368 SMART SM00331 21 253 9.2E-16 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS12105 ae256a27bcaf92692ec3fda6bcedf7ac 368 Pfam PF13672 Protein phosphatase 2C 17 229 1.1E-15 T 29-03-2018 THSYN_RS29825 bb52f0febdbb52ee50c5fbf7f617857d 162 Pfam PF03746 LamB/YcsF family 1 146 9.4E-51 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF THSYN_RS29825 bb52f0febdbb52ee50c5fbf7f617857d 162 Gene3D G3DSA:3.20.20.370 1 154 1.4E-51 T 29-03-2018 THSYN_RS29825 bb52f0febdbb52ee50c5fbf7f617857d 162 SUPERFAMILY SSF88713 1 147 1.11E-46 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS08710 2aad23dd74ad22ba8971f2715a7d00ea 200 Gene3D G3DSA:3.40.50.1240 1 197 5.8E-41 T 29-03-2018 IPR029033 Histidine phosphatase superfamily THSYN_RS08710 2aad23dd74ad22ba8971f2715a7d00ea 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 194 1.7E-39 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THSYN_RS08710 2aad23dd74ad22ba8971f2715a7d00ea 200 SMART SM00855 5 156 8.3E-11 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THSYN_RS08710 2aad23dd74ad22ba8971f2715a7d00ea 200 PIRSF PIRSF000709 5 198 5.6E-6 T 29-03-2018 THSYN_RS08710 2aad23dd74ad22ba8971f2715a7d00ea 200 SUPERFAMILY SSF53254 5 194 4.28E-43 T 29-03-2018 IPR029033 Histidine phosphatase superfamily THSYN_RS15755 9228243e55e0d5b2d809793cc17d9290 566 Gene3D G3DSA:1.20.272.10 243 362 4.8E-13 T 29-03-2018 THSYN_RS15755 9228243e55e0d5b2d809793cc17d9290 566 Gene3D G3DSA:1.10.8.60 167 242 3.6E-18 T 29-03-2018 THSYN_RS15755 9228243e55e0d5b2d809793cc17d9290 566 Pfam PF13177 DNA polymerase III, delta subunit 20 178 2.0E-41 T 29-03-2018 THSYN_RS15755 9228243e55e0d5b2d809793cc17d9290 566 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 1.9E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS15755 9228243e55e0d5b2d809793cc17d9290 566 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 1.9E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 THSYN_RS15755 9228243e55e0d5b2d809793cc17d9290 566 SMART SM00382 37 197 2.0E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS15755 9228243e55e0d5b2d809793cc17d9290 566 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 355 5.6E-127 T 29-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 THSYN_RS15755 9228243e55e0d5b2d809793cc17d9290 566 SUPERFAMILY SSF48019 244 361 3.23E-29 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 THSYN_RS15755 9228243e55e0d5b2d809793cc17d9290 566 SUPERFAMILY SSF52540 34 222 1.61E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15755 9228243e55e0d5b2d809793cc17d9290 566 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 443 556 2.4E-11 T 29-03-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS15755 9228243e55e0d5b2d809793cc17d9290 566 Gene3D G3DSA:3.40.50.300 1 166 6.5E-39 T 29-03-2018 THSYN_RS15755 9228243e55e0d5b2d809793cc17d9290 566 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 361 1.6E-29 T 29-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 THSYN_RS32300 1c86a9d9c930a816075414c86adfa591 166 Pfam PF09828 Chromate resistance exported protein 36 160 3.8E-28 T 29-03-2018 IPR018634 Chromate resistance exported protein THSYN_RS01090 286042f07e1b459448e62253ad2dd2d7 205 Gene3D G3DSA:3.30.420.10 1 181 1.0E-36 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS01090 286042f07e1b459448e62253ad2dd2d7 205 Pfam PF00929 Exonuclease 6 160 5.6E-29 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THSYN_RS01090 286042f07e1b459448e62253ad2dd2d7 205 SUPERFAMILY SSF53098 3 170 3.39E-48 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS01090 286042f07e1b459448e62253ad2dd2d7 205 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 2 160 4.1E-21 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THSYN_RS01090 286042f07e1b459448e62253ad2dd2d7 205 SMART SM00479 3 170 1.5E-32 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THSYN_RS08055 a0d7fdd156a5a1255c872abefac531fe 714 SUPERFAMILY SSF55486 217 438 4.25E-38 T 29-03-2018 THSYN_RS08055 a0d7fdd156a5a1255c872abefac531fe 714 Gene3D G3DSA:1.10.390.10 288 436 2.4E-22 T 29-03-2018 THSYN_RS08055 a0d7fdd156a5a1255c872abefac531fe 714 Pfam PF01433 Peptidase family M1 domain 294 432 1.0E-10 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THSYN_RS29020 81abd6c2ced089b51cddbe48efeea2c8 344 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 18 305 5.7E-27 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD THSYN_RS06120 fa6a13a8e6c6c227ff0c6faab28ddbd9 211 Gene3D G3DSA:3.30.460.10 113 203 5.5E-11 T 29-03-2018 THSYN_RS06120 fa6a13a8e6c6c227ff0c6faab28ddbd9 211 SUPERFAMILY SSF46785 20 105 1.75E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS06120 fa6a13a8e6c6c227ff0c6faab28ddbd9 211 SUPERFAMILY SSF81301 110 196 5.23E-11 T 29-03-2018 THSYN_RS06120 fa6a13a8e6c6c227ff0c6faab28ddbd9 211 Gene3D G3DSA:1.10.10.10 2 112 2.7E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS04530 d37aa0ac6e526af8e00286796175a03e 100 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 19 92 5.8E-31 T 29-03-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 THSYN_RS12415 0a17ff9c09f7c5faecc42b1a2c20ba66 348 SMART SM00382 54 224 0.0082 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS12415 0a17ff9c09f7c5faecc42b1a2c20ba66 348 SUPERFAMILY SSF52540 11 322 5.59E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12415 0a17ff9c09f7c5faecc42b1a2c20ba66 348 Gene3D G3DSA:1.10.287.130 264 324 1.2E-23 T 29-03-2018 THSYN_RS12415 0a17ff9c09f7c5faecc42b1a2c20ba66 348 Pfam PF03308 ArgK protein 23 293 8.1E-98 T 29-03-2018 THSYN_RS12415 0a17ff9c09f7c5faecc42b1a2c20ba66 348 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 18 321 1.8E-96 T 29-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 THSYN_RS12415 0a17ff9c09f7c5faecc42b1a2c20ba66 348 Gene3D G3DSA:3.40.50.300 53 261 2.0E-33 T 29-03-2018 THSYN_RS12415 0a17ff9c09f7c5faecc42b1a2c20ba66 348 Gene3D G3DSA:1.20.5.170 6 52 4.1E-19 T 29-03-2018 THSYN_RS28535 fc1a3b0b576ad71f9221f5bc4acbcc61 75 Gene3D G3DSA:1.20.5.170 11 60 2.0E-6 T 29-03-2018 THSYN_RS32690 30bbb887912d63aafba1db5c77611345 377 Gene3D G3DSA:2.20.25.10 12 71 6.2E-7 T 29-03-2018 THSYN_RS32690 30bbb887912d63aafba1db5c77611345 377 Pfam PF08241 Methyltransferase domain 155 274 7.2E-12 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THSYN_RS32690 30bbb887912d63aafba1db5c77611345 377 Gene3D G3DSA:3.40.50.150 136 352 3.9E-22 T 29-03-2018 THSYN_RS32690 30bbb887912d63aafba1db5c77611345 377 SUPERFAMILY SSF158997 12 74 3.53E-5 T 29-03-2018 THSYN_RS32690 30bbb887912d63aafba1db5c77611345 377 SUPERFAMILY SSF53335 142 303 2.84E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS23240 3e5d36de590c7e58f85e2a28d7e44289 166 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 17 159 45.49 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 THSYN_RS23240 3e5d36de590c7e58f85e2a28d7e44289 166 Gene3D G3DSA:3.40.140.10 6 165 1.5E-49 T 29-03-2018 THSYN_RS23240 3e5d36de590c7e58f85e2a28d7e44289 166 SUPERFAMILY SSF53927 8 159 4.35E-52 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 THSYN_RS23240 3e5d36de590c7e58f85e2a28d7e44289 166 Pfam PF14437 MafB19-like deaminase 15 159 1.8E-27 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 THSYN_RS23240 3e5d36de590c7e58f85e2a28d7e44289 166 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 62 99 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 THSYN_RS03595 6854688dea3a12769548cd85c7187300 158 Pfam PF05258 Protein of unknown function (DUF721) 26 85 1.2E-10 T 29-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 THSYN_RS18455 15c254c577d6a81b815a32491b12c219 520 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 184 208 8.5E-6 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS18455 15c254c577d6a81b815a32491b12c219 520 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 257 281 8.5E-6 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS18455 15c254c577d6a81b815a32491b12c219 520 Pfam PF00361 Proton-conducting membrane transporter 149 455 2.7E-45 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS21085 142ca55e9439e3b0126a077b9ab2d1bf 123 Pfam PF03683 Uncharacterised protein family (UPF0175) 41 105 2.0E-9 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS16285 4e75dcfb50e0e3c3129ac1388781949c 137 SUPERFAMILY SSF88723 4 117 4.49E-19 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS16285 4e75dcfb50e0e3c3129ac1388781949c 137 Pfam PF01850 PIN domain 5 116 8.9E-14 T 29-03-2018 IPR002716 PIN domain THSYN_RS16285 4e75dcfb50e0e3c3129ac1388781949c 137 Gene3D G3DSA:3.40.50.1010 4 133 7.5E-18 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS27410 3801a06bb17c411d408df566cb6c8c52 255 Gene3D G3DSA:1.10.287.110 68 161 2.8E-6 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS27410 3801a06bb17c411d408df566cb6c8c52 255 SUPERFAMILY SSF46565 119 160 3.66E-7 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS23560 32a655b52c827ba378670501641e8649 375 Pfam PF00266 Aminotransferase class-V 22 297 1.1E-10 T 29-03-2018 IPR000192 Aminotransferase class V domain THSYN_RS23560 32a655b52c827ba378670501641e8649 375 PIRSF PIRSF000524 18 374 2.8E-41 T 29-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 THSYN_RS23560 32a655b52c827ba378670501641e8649 375 Gene3D G3DSA:3.40.640.10 13 262 6.3E-30 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS23560 32a655b52c827ba378670501641e8649 375 Gene3D G3DSA:3.90.1150.10 263 373 3.0E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS23560 32a655b52c827ba378670501641e8649 375 SUPERFAMILY SSF53383 10 372 1.87E-72 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS16605 61478af9a6e081cbc749b97db0a2f100 454 Pfam PF09967 VWA-like domain (DUF2201) 331 453 1.9E-38 T 29-03-2018 IPR018698 VWA-like domain THSYN_RS16605 61478af9a6e081cbc749b97db0a2f100 454 Pfam PF13203 Putative metallopeptidase domain 11 322 8.5E-72 T 29-03-2018 IPR025154 Putative metallopeptidase domain THSYN_RS25610 abca0b843494f02044d30c88b41bfde6 794 Gene3D G3DSA:3.30.70.1230 507 720 7.0E-8 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 THSYN_RS25610 abca0b843494f02044d30c88b41bfde6 794 SUPERFAMILY SSF55073 510 651 1.88E-8 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS15925 169bdbb3bbda74d8938defb20a41b140 272 Pfam PF01578 Cytochrome C assembly protein 45 265 1.3E-33 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 THSYN_RS25500 0b2fc4a0ba9fa441e10b7184077c1e66 392 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 81 321 1.2E-42 T 29-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 THSYN_RS25500 0b2fc4a0ba9fa441e10b7184077c1e66 392 Gene3D G3DSA:3.40.50.150 67 328 1.3E-5 T 29-03-2018 THSYN_RS25500 0b2fc4a0ba9fa441e10b7184077c1e66 392 SUPERFAMILY SSF53335 25 384 8.0E-86 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS28790 56b39081c3f084959424f0b3cf1bb234 133 Pfam PF13380 CoA binding domain 16 127 6.4E-24 T 29-03-2018 IPR003781 CoA-binding GO:0048037 THSYN_RS28790 56b39081c3f084959424f0b3cf1bb234 133 Gene3D G3DSA:3.40.50.720 11 133 2.0E-17 T 29-03-2018 THSYN_RS28790 56b39081c3f084959424f0b3cf1bb234 133 SUPERFAMILY SSF51735 14 131 4.06E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS28790 56b39081c3f084959424f0b3cf1bb234 133 SMART SM00881 10 103 0.008 T 29-03-2018 IPR003781 CoA-binding GO:0048037 THSYN_RS09470 82096b3f20fd0ed3194fd76e3fd45780 148 Pfam PF01814 Hemerythrin HHE cation binding domain 5 136 8.9E-10 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THSYN_RS09470 82096b3f20fd0ed3194fd76e3fd45780 148 Gene3D G3DSA:1.20.120.520 2 141 1.0E-9 T 29-03-2018 THSYN_RS31075 6674afca4114bcf2decc8dae997ffb53 352 SUPERFAMILY SSF53850 31 349 6.53E-90 T 29-03-2018 THSYN_RS31075 6674afca4114bcf2decc8dae997ffb53 352 PIRSF PIRSF002756 3 352 3.7E-105 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 THSYN_RS31075 6674afca4114bcf2decc8dae997ffb53 352 Gene3D G3DSA:3.40.190.10 161 349 9.2E-22 T 29-03-2018 THSYN_RS31075 6674afca4114bcf2decc8dae997ffb53 352 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 31 351 2.7E-103 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 THSYN_RS31075 6674afca4114bcf2decc8dae997ffb53 352 Pfam PF12849 PBP superfamily domain 23 315 7.6E-61 T 29-03-2018 IPR024370 PBP domain THSYN_RS31075 6674afca4114bcf2decc8dae997ffb53 352 Gene3D G3DSA:3.40.190.10 28 160 2.1E-34 T 29-03-2018 THSYN_RS09080 7580e02f3cc570b052dc13ad750e06af 298 SUPERFAMILY SSF53335 47 297 9.69E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS09080 7580e02f3cc570b052dc13ad750e06af 298 Gene3D G3DSA:3.40.50.150 28 292 2.6E-32 T 29-03-2018 THSYN_RS09080 7580e02f3cc570b052dc13ad750e06af 298 Pfam PF08241 Methyltransferase domain 84 183 9.7E-19 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THSYN_RS09080 7580e02f3cc570b052dc13ad750e06af 298 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 11 260 2.6E-4 T 29-03-2018 IPR020803 Polyketide synthase, methyltransferase domain THSYN_RS18590 65ed6ea0b28451e4f2915d049a812aa7 208 Gene3D G3DSA:2.40.50.180 15 90 0.023 T 29-03-2018 THSYN_RS18590 65ed6ea0b28451e4f2915d049a812aa7 208 SMART SM00260 63 201 2.1E-12 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS18590 65ed6ea0b28451e4f2915d049a812aa7 208 Gene3D G3DSA:2.30.30.40 150 195 5.0E-4 T 29-03-2018 THSYN_RS18590 65ed6ea0b28451e4f2915d049a812aa7 208 Pfam PF01584 CheW-like domain 68 202 2.0E-22 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS18590 65ed6ea0b28451e4f2915d049a812aa7 208 Gene3D G3DSA:2.40.50.180 91 149 1.5E-12 T 29-03-2018 THSYN_RS18590 65ed6ea0b28451e4f2915d049a812aa7 208 SUPERFAMILY SSF50341 68 202 1.2E-23 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS27560 bd004680655c366b72cd4363a6c3d959 290 Pfam PF09163 Formate dehydrogenase N, transmembrane 243 286 1.0E-19 T 29-03-2018 IPR015246 Formate dehydrogenase, transmembrane THSYN_RS27560 bd004680655c366b72cd4363a6c3d959 290 Gene3D G3DSA:3.30.70.20 150 254 1.8E-21 T 29-03-2018 THSYN_RS27560 bd004680655c366b72cd4363a6c3d959 290 Pfam PF13247 4Fe-4S dicluster domain 89 184 1.5E-23 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS27560 bd004680655c366b72cd4363a6c3d959 290 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 130 141 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS27560 bd004680655c366b72cd4363a6c3d959 290 Gene3D G3DSA:3.30.70.20 110 149 4.8E-16 T 29-03-2018 THSYN_RS27560 bd004680655c366b72cd4363a6c3d959 290 Gene3D G3DSA:3.30.70.20 10 38 0.003 T 29-03-2018 THSYN_RS27560 bd004680655c366b72cd4363a6c3d959 290 PIRSF PIRSF036298 1 290 4.2E-146 T 29-03-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 THSYN_RS27560 bd004680655c366b72cd4363a6c3d959 290 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 286 1.6E-135 T 29-03-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 THSYN_RS27560 bd004680655c366b72cd4363a6c3d959 290 Gene3D G3DSA:3.30.70.20 39 109 1.3E-22 T 29-03-2018 THSYN_RS27560 bd004680655c366b72cd4363a6c3d959 290 SUPERFAMILY SSF54862 26 275 1.99E-71 T 29-03-2018 THSYN_RS27560 bd004680655c366b72cd4363a6c3d959 290 Gene3D G3DSA:1.20.5.480 255 288 8.7E-18 T 29-03-2018 THSYN_RS17155 d15442d7544958e75c0986d9ee912fca 260 Gene3D G3DSA:1.10.10.60 3 59 6.5E-20 T 29-03-2018 THSYN_RS17155 d15442d7544958e75c0986d9ee912fca 260 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 68 9.4E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THSYN_RS17155 d15442d7544958e75c0986d9ee912fca 260 Gene3D G3DSA:1.10.357.10 60 226 1.0E-28 T 29-03-2018 THSYN_RS17155 d15442d7544958e75c0986d9ee912fca 260 SUPERFAMILY SSF48498 118 222 4.34E-16 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THSYN_RS17155 d15442d7544958e75c0986d9ee912fca 260 SUPERFAMILY SSF46689 11 88 9.75E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS17155 d15442d7544958e75c0986d9ee912fca 260 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 66 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site THSYN_RS17155 d15442d7544958e75c0986d9ee912fca 260 Pfam PF09209 Domain of unknown function (DUF1956) 106 220 5.0E-19 T 29-03-2018 IPR015292 Transcription regulator YbiH, C-terminal THSYN_RS17155 d15442d7544958e75c0986d9ee912fca 260 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 6.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THSYN_RS17155 d15442d7544958e75c0986d9ee912fca 260 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 6.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THSYN_RS26845 6e5316eb11fad5de969cc75eecf2e50c 76 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 40 1.1E-5 T 29-03-2018 THSYN_RS26845 6e5316eb11fad5de969cc75eecf2e50c 76 SUPERFAMILY SSF143120 1 40 5.1E-8 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS26845 6e5316eb11fad5de969cc75eecf2e50c 76 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 40 1.4E-8 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS26845 6e5316eb11fad5de969cc75eecf2e50c 76 Gene3D G3DSA:3.40.1620.10 1 39 2.1E-13 T 29-03-2018 THSYN_RS01870 7002ddc5468aabc0f5669383b510b82c 66 Pfam PF02597 ThiS family 3 66 5.9E-13 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 THSYN_RS01870 7002ddc5468aabc0f5669383b510b82c 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 2.2E-21 T 29-03-2018 IPR010035 ThiS, thiamine-biosynthesis THSYN_RS01870 7002ddc5468aabc0f5669383b510b82c 66 Gene3D G3DSA:3.10.20.30 1 66 2.1E-21 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS01870 7002ddc5468aabc0f5669383b510b82c 66 SUPERFAMILY SSF54285 2 65 2.62E-16 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THSYN_RS12310 5e5edfce23a3e8096898bd8223512b3f 722 Gene3D G3DSA:3.40.50.300 148 704 6.4E-4 T 29-03-2018 THSYN_RS14070 c1e3cb984a3f11eec1a635cd97e8d999 323 Pfam PF12784 PD-(D/E)XK nuclease family transposase 7 229 9.0E-52 T 29-03-2018 THSYN_RS14070 c1e3cb984a3f11eec1a635cd97e8d999 323 Gene3D G3DSA:1.20.1000.10 51 316 2.0E-5 T 29-03-2018 THSYN_RS14070 c1e3cb984a3f11eec1a635cd97e8d999 323 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 8 262 3.5E-29 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA THSYN_RS09610 848118a94a489d268e0483928f913485 179 Gene3D G3DSA:3.40.50.700 1 176 2.5E-41 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09610 848118a94a489d268e0483928f913485 179 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 16 162 4.4E-32 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09610 848118a94a489d268e0483928f913485 179 SUPERFAMILY SSF56770 5 171 2.09E-40 T 29-03-2018 THSYN_RS28140 d395cf986ca550705ff4da1e61dcedee 198 Gene3D G3DSA:3.40.50.300 1 198 2.0E-37 T 29-03-2018 THSYN_RS28140 d395cf986ca550705ff4da1e61dcedee 198 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 185 1.7E-46 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 THSYN_RS28140 d395cf986ca550705ff4da1e61dcedee 198 Pfam PF01121 Dephospho-CoA kinase 4 176 7.6E-58 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 THSYN_RS28140 d395cf986ca550705ff4da1e61dcedee 198 SUPERFAMILY SSF52540 1 189 3.62E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS28140 d395cf986ca550705ff4da1e61dcedee 198 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 194 26.792 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 THSYN_RS13600 7390331f2ca1c61b10d8a838aec0d802 439 Gene3D G3DSA:3.30.2290.10 1 215 9.1E-10 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain THSYN_RS13600 7390331f2ca1c61b10d8a838aec0d802 439 Pfam PF01523 Putative modulator of DNA gyrase 30 299 1.0E-18 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 THSYN_RS13600 7390331f2ca1c61b10d8a838aec0d802 439 SUPERFAMILY SSF111283 16 437 8.76E-58 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 Gene3D G3DSA:2.60.40.1080 963 1048 1.8E-10 T 29-03-2018 THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 Gene3D G3DSA:2.60.40.1080 1049 1129 2.5E-11 T 29-03-2018 THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 Gene3D G3DSA:2.60.40.10 516 678 0.0034 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 Gene3D G3DSA:2.40.50.70 1130 1179 0.0017 T 29-03-2018 THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 Gene3D G3DSA:2.40.50.70 1221 1283 1.2E-4 T 29-03-2018 THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 SUPERFAMILY SSF49373 1050 1126 7.85E-6 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 Gene3D G3DSA:2.60.40.10 23 87 0.0076 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 Gene3D G3DSA:2.60.40.10 874 960 0.33 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 Gene3D G3DSA:2.60.40.10 771 864 0.031 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 Gene3D G3DSA:2.60.40.10 679 767 0.031 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 Gene3D G3DSA:2.60.40.10 316 429 1.2E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 Pfam PF13205 Bacterial Ig-like domain 455 559 2.7E-10 T 29-03-2018 IPR032812 SbsA, Ig-like domain THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 SMART SM00635 964 1046 1.1E-8 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 THSYN_RS29910 ed8c89fda7ed7b30a902236c794db49f 2986 SMART SM00635 1051 1133 6.8E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 THSYN_RS11650 0182a8f1ffaf039720810045a0c50362 117 SUPERFAMILY SSF81301 13 117 2.01E-13 T 29-03-2018 THSYN_RS11650 0182a8f1ffaf039720810045a0c50362 117 Pfam PF01909 Nucleotidyltransferase domain 31 69 9.1E-7 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS11650 0182a8f1ffaf039720810045a0c50362 117 Gene3D G3DSA:3.30.460.10 10 117 2.7E-13 T 29-03-2018 THSYN_RS01865 d0d21590a4df28bef4b427a38be84b35 265 Hamap MF_00443 Thiazole synthase [thiG]. 10 265 42.29 T 29-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 THSYN_RS01865 d0d21590a4df28bef4b427a38be84b35 265 Gene3D G3DSA:3.20.20.70 8 265 4.3E-48 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS01865 d0d21590a4df28bef4b427a38be84b35 265 Pfam PF05690 Thiazole biosynthesis protein ThiG 13 259 3.5E-109 T 29-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 THSYN_RS01865 d0d21590a4df28bef4b427a38be84b35 265 SUPERFAMILY SSF110399 9 249 4.58E-88 T 29-03-2018 THSYN_RS08585 408f2f8af194930c71ae8c983195bd01 144 SUPERFAMILY SSF52833 27 143 2.53E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS08585 408f2f8af194930c71ae8c983195bd01 144 Gene3D G3DSA:3.40.30.10 38 144 5.1E-28 T 29-03-2018 THSYN_RS08585 408f2f8af194930c71ae8c983195bd01 144 Pfam PF00085 Thioredoxin 43 142 1.4E-25 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 THSYN_RS08585 408f2f8af194930c71ae8c983195bd01 144 ProSitePatterns PS00194 Thioredoxin family active site. 61 79 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THSYN_RS08585 408f2f8af194930c71ae8c983195bd01 144 PIRSF PIRSF000077 39 143 1.7E-28 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THSYN_RS08585 408f2f8af194930c71ae8c983195bd01 144 PRINTS PR00421 Thioredoxin family signature 60 68 3.9E-9 T 29-03-2018 THSYN_RS08585 408f2f8af194930c71ae8c983195bd01 144 PRINTS PR00421 Thioredoxin family signature 68 77 3.9E-9 T 29-03-2018 THSYN_RS08585 408f2f8af194930c71ae8c983195bd01 144 PRINTS PR00421 Thioredoxin family signature 108 119 3.9E-9 T 29-03-2018 THSYN_RS02270 c3d5cfa9a0b4928dc35039fb0c56381d 337 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 8 238 9.7E-33 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA THSYN_RS02270 c3d5cfa9a0b4928dc35039fb0c56381d 337 Gene3D G3DSA:1.20.1000.10 54 328 1.7E-5 T 29-03-2018 THSYN_RS02270 c3d5cfa9a0b4928dc35039fb0c56381d 337 Pfam PF12784 PD-(D/E)XK nuclease family transposase 7 229 4.4E-53 T 29-03-2018 THSYN_RS21195 80bae55d621c34c22bab484a1c85858c 174 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 8.5E-20 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 THSYN_RS21195 80bae55d621c34c22bab484a1c85858c 174 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 135 151 8.5E-20 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 THSYN_RS21195 80bae55d621c34c22bab484a1c85858c 174 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 93 108 8.5E-20 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 THSYN_RS21195 80bae55d621c34c22bab484a1c85858c 174 Pfam PF01252 Signal peptidase (SPase) II 8 155 4.8E-39 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 THSYN_RS21195 80bae55d621c34c22bab484a1c85858c 174 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 160 16.814 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 THSYN_RS21195 80bae55d621c34c22bab484a1c85858c 174 TIGRFAM TIGR00077 lspA: signal peptidase II 4 158 1.4E-38 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 THSYN_RS21195 80bae55d621c34c22bab484a1c85858c 174 ProSitePatterns PS00855 Signal peptidases II signature. 96 108 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 THSYN_RS00125 cec2ad89396fb6d5ec0ee443e5f19e9c 142 SMART SM00450 39 136 9.8E-27 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS00125 cec2ad89396fb6d5ec0ee443e5f19e9c 142 SUPERFAMILY SSF52821 14 138 4.32E-35 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS00125 cec2ad89396fb6d5ec0ee443e5f19e9c 142 Pfam PF00581 Rhodanese-like domain 46 133 3.8E-18 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS00125 cec2ad89396fb6d5ec0ee443e5f19e9c 142 Gene3D G3DSA:3.40.250.10 40 142 1.1E-29 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS07295 c7b3530c66d498ca3bbd50d81b5a9311 355 SUPERFAMILY SSF51161 36 317 6.72E-73 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS07295 c7b3530c66d498ca3bbd50d81b5a9311 355 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 26 91 6.4E-9 T 29-03-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 THSYN_RS07295 c7b3530c66d498ca3bbd50d81b5a9311 355 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 269 297 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 THSYN_RS07295 c7b3530c66d498ca3bbd50d81b5a9311 355 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 225 259 1.4E-5 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS07295 c7b3530c66d498ca3bbd50d81b5a9311 355 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 130 163 7.5E-10 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS07295 c7b3530c66d498ca3bbd50d81b5a9311 355 Gene3D G3DSA:2.160.10.10 97 137 1.1E-9 T 29-03-2018 THSYN_RS07295 c7b3530c66d498ca3bbd50d81b5a9311 355 Gene3D G3DSA:2.160.10.10 138 312 3.4E-51 T 29-03-2018 THSYN_RS07295 c7b3530c66d498ca3bbd50d81b5a9311 355 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 15 327 32.309 T 29-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 THSYN_RS07295 c7b3530c66d498ca3bbd50d81b5a9311 355 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 28 330 4.7E-91 T 29-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 THSYN_RS27490 0f499ca04392d73346dfedcc79b20ca3 116 Gene3D G3DSA:2.30.30.110 1 113 4.1E-5 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS27490 0f499ca04392d73346dfedcc79b20ca3 116 SUPERFAMILY SSF50118 3 110 1.7E-5 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS27490 0f499ca04392d73346dfedcc79b20ca3 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 105 1.5E-4 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS26985 ad3222e386a06eaeb2b9406773caad8e 83 SUPERFAMILY SSF46689 5 74 8.42E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS26985 ad3222e386a06eaeb2b9406773caad8e 83 Pfam PF04255 Protein of unknown function (DUF433) 10 65 6.2E-22 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS26985 ad3222e386a06eaeb2b9406773caad8e 83 Gene3D G3DSA:1.10.10.10 10 72 1.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26880 9c1f7dd02e590cc128d259be8a93708f 531 SUPERFAMILY SSF56300 31 318 9.22E-69 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS26880 9c1f7dd02e590cc128d259be8a93708f 531 Pfam PF02872 5'-nucleotidase, C-terminal domain 326 474 1.6E-36 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS26880 9c1f7dd02e590cc128d259be8a93708f 531 Pfam PF00149 Calcineurin-like phosphoesterase 34 252 3.3E-9 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS26880 9c1f7dd02e590cc128d259be8a93708f 531 Gene3D G3DSA:3.90.780.10 335 512 4.0E-53 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS26880 9c1f7dd02e590cc128d259be8a93708f 531 Gene3D G3DSA:3.60.21.10 29 334 1.1E-69 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS26880 9c1f7dd02e590cc128d259be8a93708f 531 PRINTS PR01607 Apyrase family signature 263 283 1.1E-31 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS26880 9c1f7dd02e590cc128d259be8a93708f 531 PRINTS PR01607 Apyrase family signature 216 233 1.1E-31 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS26880 9c1f7dd02e590cc128d259be8a93708f 531 PRINTS PR01607 Apyrase family signature 31 49 1.1E-31 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS26880 9c1f7dd02e590cc128d259be8a93708f 531 PRINTS PR01607 Apyrase family signature 379 402 1.1E-31 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS26880 9c1f7dd02e590cc128d259be8a93708f 531 PRINTS PR01607 Apyrase family signature 235 258 1.1E-31 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS26880 9c1f7dd02e590cc128d259be8a93708f 531 PRINTS PR01607 Apyrase family signature 448 467 1.1E-31 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS26880 9c1f7dd02e590cc128d259be8a93708f 531 SUPERFAMILY SSF55816 322 511 4.05E-50 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS16630 4faf0997cc190da8bc3fae28ea222e9d 101 Pfam PF03683 Uncharacterised protein family (UPF0175) 26 96 5.8E-19 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS24235 baa9e3fdf05347f6474f8ef4d931e6fd 1054 Pfam PF07589 PEP-CTERM motif 1029 1052 2.1E-7 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS24235 baa9e3fdf05347f6474f8ef4d931e6fd 1054 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 1030 1049 3.7E-4 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS16325 8a6d50d9f770dcbfa56af7ffb7587e2b 356 SUPERFAMILY SSF52266 27 260 4.0E-13 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain THSYN_RS16325 8a6d50d9f770dcbfa56af7ffb7587e2b 356 SUPERFAMILY SSF52266 295 323 4.0E-13 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain THSYN_RS16325 8a6d50d9f770dcbfa56af7ffb7587e2b 356 Pfam PF00657 GDSL-like Lipase/Acylhydrolase 30 316 9.8E-6 T 29-03-2018 IPR001087 GDSL lipase/esterase GO:0016788 THSYN_RS16325 8a6d50d9f770dcbfa56af7ffb7587e2b 356 Gene3D G3DSA:3.40.50.1110 17 329 3.0E-60 T 29-03-2018 THSYN_RS00595 060c5e126e449eaf1db4f8c64bc9c62e 119 Gene3D G3DSA:1.10.10.10 5 116 4.0E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS00595 060c5e126e449eaf1db4f8c64bc9c62e 119 SUPERFAMILY SSF46785 47 99 6.43E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS22810 02b93df21c6266c58f3fe8d6438331c9 501 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 453 462 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THSYN_RS22810 02b93df21c6266c58f3fe8d6438331c9 501 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 52 77 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THSYN_RS22810 02b93df21c6266c58f3fe8d6438331c9 501 Pfam PF00374 Nickel-dependent hydrogenase 52 129 4.3E-17 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THSYN_RS22810 02b93df21c6266c58f3fe8d6438331c9 501 Pfam PF00374 Nickel-dependent hydrogenase 267 462 5.9E-14 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THSYN_RS22810 02b93df21c6266c58f3fe8d6438331c9 501 Gene3D G3DSA:1.10.645.10 10 242 6.5E-57 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS22810 02b93df21c6266c58f3fe8d6438331c9 501 Gene3D G3DSA:1.10.645.10 243 462 3.0E-41 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS22810 02b93df21c6266c58f3fe8d6438331c9 501 SUPERFAMILY SSF56762 16 462 8.63E-123 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS25110 31a089ee0789bfebd30fcead8e39ef51 627 Gene3D G3DSA:3.40.50.620 227 623 6.2E-65 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS25110 31a089ee0789bfebd30fcead8e39ef51 627 PIRSF PIRSF001589 1 626 1.3E-134 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS25110 31a089ee0789bfebd30fcead8e39ef51 627 SUPERFAMILY SSF56235 1 229 8.06E-62 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS25110 31a089ee0789bfebd30fcead8e39ef51 627 Pfam PF00733 Asparagine synthase 247 620 1.4E-77 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THSYN_RS25110 31a089ee0789bfebd30fcead8e39ef51 627 Gene3D G3DSA:3.60.20.10 1 226 7.0E-53 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS25110 31a089ee0789bfebd30fcead8e39ef51 627 SUPERFAMILY SSF52402 475 612 3.4E-69 T 29-03-2018 THSYN_RS25110 31a089ee0789bfebd30fcead8e39ef51 627 SUPERFAMILY SSF52402 236 390 3.4E-69 T 29-03-2018 THSYN_RS25110 31a089ee0789bfebd30fcead8e39ef51 627 Pfam PF13537 Glutamine amidotransferase domain 48 168 3.6E-45 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain THSYN_RS25110 31a089ee0789bfebd30fcead8e39ef51 627 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 556 1.3E-134 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS32330 561edd628bdd84d46672dd983cef729a 222 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 123 139 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THSYN_RS32330 561edd628bdd84d46672dd983cef729a 222 Pfam PF00472 RF-1 domain 114 193 9.2E-22 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THSYN_RS32330 561edd628bdd84d46672dd983cef729a 222 TIGRFAM TIGR03072 release_prfH: putative peptide chain release factor H 8 208 6.6E-67 T 29-03-2018 IPR017509 Putative peptide chain release factor H THSYN_RS32330 561edd628bdd84d46672dd983cef729a 222 Gene3D G3DSA:3.30.160.20 108 185 3.5E-23 T 29-03-2018 THSYN_RS32330 561edd628bdd84d46672dd983cef729a 222 SUPERFAMILY SSF75620 4 205 4.84E-47 T 29-03-2018 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 Gene3D G3DSA:1.25.40.10 313 385 2.1E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 Gene3D G3DSA:1.25.40.10 465 554 1.5E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 Pfam PF13181 Tetratricopeptide repeat 451 477 0.0055 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 Gene3D G3DSA:1.25.40.10 386 416 0.054 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 Gene3D G3DSA:1.25.40.10 417 464 2.6E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 SUPERFAMILY SSF48452 231 396 6.01E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 SUPERFAMILY SSF48452 424 456 6.01E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 Gene3D G3DSA:1.25.40.10 48 285 6.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 Gene3D G3DSA:1.10.287.1110 286 305 2.6E-5 T 29-03-2018 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 SMART SM00028 449 482 3.2 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 SMART SM00028 346 393 400.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 SMART SM00028 401 434 53.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 SMART SM00028 258 298 52.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS00245 2f9f75ae68a5b932f7524d6799229a86 559 SUPERFAMILY SSF48452 401 505 1.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19990 eccc3a00d0cde6eb60e84837fb1ce042 459 Gene3D G3DSA:1.10.1140.10 359 456 1.1E-12 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS19990 eccc3a00d0cde6eb60e84837fb1ce042 459 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 3 459 53.026 T 29-03-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS19990 eccc3a00d0cde6eb60e84837fb1ce042 459 Gene3D G3DSA:3.40.50.300 24 350 1.2E-81 T 29-03-2018 THSYN_RS19990 eccc3a00d0cde6eb60e84837fb1ce042 459 SUPERFAMILY SSF52540 79 355 1.28E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19990 eccc3a00d0cde6eb60e84837fb1ce042 459 SUPERFAMILY SSF47917 363 417 2.01E-6 T 29-03-2018 THSYN_RS19990 eccc3a00d0cde6eb60e84837fb1ce042 459 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 341 350 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS19990 eccc3a00d0cde6eb60e84837fb1ce042 459 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 132 350 1.4E-63 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THSYN_RS22130 cccfb149fe727c4751f1a589bab38d31 222 Gene3D G3DSA:3.40.50.360 1 220 1.4E-50 T 29-03-2018 IPR029039 Flavoprotein-like domain THSYN_RS22130 cccfb149fe727c4751f1a589bab38d31 222 Pfam PF02525 Flavodoxin-like fold 1 207 1.7E-51 T 29-03-2018 IPR003680 Flavodoxin-like fold THSYN_RS22130 cccfb149fe727c4751f1a589bab38d31 222 SUPERFAMILY SSF52218 1 211 6.77E-61 T 29-03-2018 IPR029039 Flavoprotein-like domain THSYN_RS22285 87eb978764e3668ce0da67b6cd64a721 230 Gene3D G3DSA:3.20.20.70 3 226 6.7E-81 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS22285 87eb978764e3668ce0da67b6cd64a721 230 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THSYN_RS22285 87eb978764e3668ce0da67b6cd64a721 230 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 206 4.1E-93 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THSYN_RS22285 87eb978764e3668ce0da67b6cd64a721 230 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 203 1.7E-89 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THSYN_RS22285 87eb978764e3668ce0da67b6cd64a721 230 SUPERFAMILY SSF51366 5 211 1.73E-71 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THSYN_RS22285 87eb978764e3668ce0da67b6cd64a721 230 PIRSF PIRSF001461 1 229 6.2E-98 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THSYN_RS22285 87eb978764e3668ce0da67b6cd64a721 230 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 136 158 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THSYN_RS25115 eff8a93361df22af0dbb7004e70f246f 241 Pfam PF08241 Methyltransferase domain 90 138 2.5E-6 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THSYN_RS25115 eff8a93361df22af0dbb7004e70f246f 241 SUPERFAMILY SSF53335 89 147 8.44E-13 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS25115 eff8a93361df22af0dbb7004e70f246f 241 SUPERFAMILY SSF53335 179 210 8.44E-13 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS25115 eff8a93361df22af0dbb7004e70f246f 241 Gene3D G3DSA:3.40.50.150 80 230 8.3E-14 T 29-03-2018 THSYN_RS04645 af8f375ced5a2bc8b772c80af9a1930b 99 Gene3D G3DSA:2.40.50.110 14 97 7.3E-12 T 29-03-2018 THSYN_RS04645 af8f375ced5a2bc8b772c80af9a1930b 99 Pfam PF08239 Bacterial SH3 domain 45 95 1.9E-12 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type THSYN_RS12240 1d68279462607be21e699e9c77f56b7c 354 Gene3D G3DSA:2.130.10.10 264 349 1.2E-7 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS12240 1d68279462607be21e699e9c77f56b7c 354 SUPERFAMILY SSF51004 267 341 1.44E-10 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain THSYN_RS12240 1d68279462607be21e699e9c77f56b7c 354 Gene3D G3DSA:2.160.20.50 178 250 5.4E-12 T 29-03-2018 THSYN_RS12240 1d68279462607be21e699e9c77f56b7c 354 Pfam PF01391 Collagen triple helix repeat (20 copies) 193 247 1.0E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat THSYN_RS08295 62b609c288e83a9ec9ee1a95cc61defc 223 Gene3D G3DSA:3.40.50.300 1 223 2.8E-65 T 29-03-2018 THSYN_RS08295 62b609c288e83a9ec9ee1a95cc61defc 223 SMART SM00382 34 218 3.5E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS08295 62b609c288e83a9ec9ee1a95cc61defc 223 SUPERFAMILY SSF52540 6 221 2.08E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08295 62b609c288e83a9ec9ee1a95cc61defc 223 Pfam PF00005 ABC transporter 25 170 2.8E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS08295 62b609c288e83a9ec9ee1a95cc61defc 223 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS03770 2a6150086a2b7a7f55e12ddfe02ec8be 392 Pfam PF03235 Protein of unknown function DUF262 46 120 7.5E-19 T 29-03-2018 IPR004919 Domain of unknown function DUF262 THSYN_RS27530 d91dcc524ab351af7330c85707186d66 317 SUPERFAMILY SSF144020 23 311 4.05E-70 T 29-03-2018 IPR024064 FdhE-like THSYN_RS27530 d91dcc524ab351af7330c85707186d66 317 PIRSF PIRSF018296 1 315 1.1E-77 T 29-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 THSYN_RS27530 d91dcc524ab351af7330c85707186d66 317 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 5 310 4.1E-70 T 29-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 THSYN_RS27530 d91dcc524ab351af7330c85707186d66 317 Hamap MF_00611 Protein FdhE [fdhE]. 3 312 31.803 T 29-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 THSYN_RS27530 d91dcc524ab351af7330c85707186d66 317 Pfam PF04216 Protein involved in formate dehydrogenase formation 26 309 1.3E-84 T 29-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 THSYN_RS27530 d91dcc524ab351af7330c85707186d66 317 Gene3D G3DSA:3.90.1670.10 19 314 2.0E-78 T 29-03-2018 IPR024064 FdhE-like THSYN_RS27995 aa374c7fbf133cfcabec509dec84f5c6 231 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 78 98 2.3E-4 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS27995 aa374c7fbf133cfcabec509dec84f5c6 231 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 78 137 2.2E-19 T 29-03-2018 IPR013362 Pilus modification type IV, PilV THSYN_RS27995 aa374c7fbf133cfcabec509dec84f5c6 231 Pfam PF07963 Prokaryotic N-terminal methylation motif 77 99 5.0E-6 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS16170 e28763ba18ba9bae7f48b5afe84fc056 219 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 4 198 2.1E-48 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 THSYN_RS16170 e28763ba18ba9bae7f48b5afe84fc056 219 Hamap MF_00165 Thymidylate kinase [tmk]. 6 207 30.357 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 THSYN_RS16170 e28763ba18ba9bae7f48b5afe84fc056 219 Pfam PF02223 Thymidylate kinase 10 197 2.0E-45 T 29-03-2018 THSYN_RS16170 e28763ba18ba9bae7f48b5afe84fc056 219 Gene3D G3DSA:3.40.50.300 2 215 1.6E-53 T 29-03-2018 THSYN_RS16170 e28763ba18ba9bae7f48b5afe84fc056 219 SUPERFAMILY SSF52540 1 208 1.33E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04595 501261029713676cd795f5a37836b2e0 1013 Pfam PF03781 Sulfatase-modifying factor enzyme 1 604 776 3.6E-48 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS04595 501261029713676cd795f5a37836b2e0 1013 Pfam PF03781 Sulfatase-modifying factor enzyme 1 271 567 2.4E-58 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS04595 501261029713676cd795f5a37836b2e0 1013 Pfam PF03781 Sulfatase-modifying factor enzyme 1 949 1002 6.1E-12 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS04595 501261029713676cd795f5a37836b2e0 1013 Gene3D G3DSA:3.90.1580.10 664 892 7.8E-52 T 29-03-2018 THSYN_RS04595 501261029713676cd795f5a37836b2e0 1013 Gene3D G3DSA:3.90.1580.10 594 663 3.5E-18 T 29-03-2018 THSYN_RS04595 501261029713676cd795f5a37836b2e0 1013 Gene3D G3DSA:3.90.1580.10 939 1013 6.8E-15 T 29-03-2018 THSYN_RS04595 501261029713676cd795f5a37836b2e0 1013 Gene3D G3DSA:3.90.1580.10 262 575 1.9E-77 T 29-03-2018 THSYN_RS04595 501261029713676cd795f5a37836b2e0 1013 SUPERFAMILY SSF56436 949 1009 1.53E-14 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS04595 501261029713676cd795f5a37836b2e0 1013 SUPERFAMILY SSF56436 839 884 5.34E-68 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS04595 501261029713676cd795f5a37836b2e0 1013 SUPERFAMILY SSF56436 603 777 5.34E-68 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS04595 501261029713676cd795f5a37836b2e0 1013 SUPERFAMILY SSF56436 522 567 2.45E-72 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS04595 501261029713676cd795f5a37836b2e0 1013 SUPERFAMILY SSF56436 270 470 2.45E-72 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS27510 66d1aca92bb2a3f21818e8e9cc6ef7b7 226 Gene3D G3DSA:3.40.50.280 97 225 2.4E-22 T 29-03-2018 THSYN_RS27510 66d1aca92bb2a3f21818e8e9cc6ef7b7 226 Pfam PF02607 B12 binding domain 23 91 1.0E-10 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THSYN_RS27510 66d1aca92bb2a3f21818e8e9cc6ef7b7 226 Pfam PF02310 B12 binding domain 104 194 4.5E-14 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 THSYN_RS27510 66d1aca92bb2a3f21818e8e9cc6ef7b7 226 SUPERFAMILY SSF52242 100 212 6.02E-22 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 THSYN_RS10105 205dd5474d2fff18a1c679d2cd98a0dc 411 Pfam PF03441 FAD binding domain of DNA photolyase 84 211 5.6E-25 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 THSYN_RS10105 205dd5474d2fff18a1c679d2cd98a0dc 411 Gene3D G3DSA:1.25.40.80 2 94 9.2E-17 T 29-03-2018 THSYN_RS10105 205dd5474d2fff18a1c679d2cd98a0dc 411 Gene3D G3DSA:1.10.579.10 95 244 6.5E-29 T 29-03-2018 THSYN_RS10105 205dd5474d2fff18a1c679d2cd98a0dc 411 PRINTS PR00147 DNA photolyase signature 130 146 8.6E-7 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 THSYN_RS10105 205dd5474d2fff18a1c679d2cd98a0dc 411 PRINTS PR00147 DNA photolyase signature 189 203 8.6E-7 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 THSYN_RS10105 205dd5474d2fff18a1c679d2cd98a0dc 411 PRINTS PR00147 DNA photolyase signature 150 168 8.6E-7 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 THSYN_RS10105 205dd5474d2fff18a1c679d2cd98a0dc 411 SUPERFAMILY SSF48173 10 214 1.3E-50 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 THSYN_RS03990 9f095cf7a468600c41f958abb7aa8cce 258 SUPERFAMILY SSF55729 4 235 3.5E-89 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS03990 9f095cf7a468600c41f958abb7aa8cce 258 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 36 212 4.3E-70 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 THSYN_RS03990 9f095cf7a468600c41f958abb7aa8cce 258 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 258 95.819 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 THSYN_RS03990 9f095cf7a468600c41f958abb7aa8cce 258 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 39 224 6.6E-64 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 THSYN_RS19890 e7003045aa84efc9ae0f5f035f30d887 124 Gene3D G3DSA:3.40.50.10580 10 115 5.9E-8 T 29-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS19890 e7003045aa84efc9ae0f5f035f30d887 124 Pfam PF01990 ATP synthase (F/14-kDa) subunit 15 91 1.9E-5 T 29-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS19890 e7003045aa84efc9ae0f5f035f30d887 124 SUPERFAMILY SSF159468 14 93 5.23E-10 T 29-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 Pfam PF14698 Argininosuccinate lyase C-terminal 375 443 1.6E-24 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 PRINTS PR00145 Argininosuccinate lyase family signature 205 221 2.5E-69 T 29-03-2018 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 PRINTS PR00145 Argininosuccinate lyase family signature 287 303 2.5E-69 T 29-03-2018 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 PRINTS PR00145 Argininosuccinate lyase family signature 113 135 2.5E-69 T 29-03-2018 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 PRINTS PR00145 Argininosuccinate lyase family signature 154 174 2.5E-69 T 29-03-2018 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 PRINTS PR00145 Argininosuccinate lyase family signature 322 341 2.5E-69 T 29-03-2018 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 PRINTS PR00145 Argininosuccinate lyase family signature 243 267 2.5E-69 T 29-03-2018 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 PRINTS PR00149 Fumarate lyase superfamily signature 243 270 2.4E-31 T 29-03-2018 IPR000362 Fumarate lyase family THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 PRINTS PR00149 Fumarate lyase superfamily signature 287 303 2.4E-31 T 29-03-2018 IPR000362 Fumarate lyase family THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 PRINTS PR00149 Fumarate lyase superfamily signature 114 132 2.4E-31 T 29-03-2018 IPR000362 Fumarate lyase family THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 PRINTS PR00149 Fumarate lyase superfamily signature 159 177 2.4E-31 T 29-03-2018 IPR000362 Fumarate lyase family THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 Gene3D G3DSA:1.10.40.30 387 444 1.9E-25 T 29-03-2018 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 ProSitePatterns PS00163 Fumarate lyases signature. 287 296 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 Gene3D G3DSA:1.20.200.10 119 386 1.1E-102 T 29-03-2018 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 Hamap MF_00006 Argininosuccinate lyase [argH]. 14 465 44.198 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 SUPERFAMILY SSF48557 16 465 3.93E-154 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 TIGRFAM TIGR00838 argH: argininosuccinate lyase 16 466 8.6E-193 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 Pfam PF00206 Lyase 18 312 7.1E-81 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal THSYN_RS16810 de278596001fdf952a4b680582483dbe 469 Gene3D G3DSA:1.10.275.10 14 118 3.2E-39 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal THSYN_RS28970 11e0f7e09a1508b29af1032a7d0982da 318 Gene3D G3DSA:3.90.25.10 180 315 2.3E-36 T 29-03-2018 THSYN_RS28970 11e0f7e09a1508b29af1032a7d0982da 318 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 2 313 46.959 T 29-03-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 THSYN_RS28970 11e0f7e09a1508b29af1032a7d0982da 318 SUPERFAMILY SSF51735 4 315 7.14E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS28970 11e0f7e09a1508b29af1032a7d0982da 318 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 226 8.9E-73 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THSYN_RS28970 11e0f7e09a1508b29af1032a7d0982da 318 Gene3D G3DSA:3.40.50.720 4 179 1.9E-14 T 29-03-2018 THSYN_RS28905 42df47b22465972999a96b1347cec6b3 218 Gene3D G3DSA:1.20.1440.100 16 79 3.0E-29 T 29-03-2018 THSYN_RS28905 42df47b22465972999a96b1347cec6b3 218 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 3 201 3.7E-40 T 29-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like THSYN_RS28905 42df47b22465972999a96b1347cec6b3 218 Gene3D G3DSA:3.40.50.1000 80 208 1.6E-11 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS28905 42df47b22465972999a96b1347cec6b3 218 Pfam PF12710 haloacid dehalogenase-like hydrolase 4 187 5.9E-38 T 29-03-2018 THSYN_RS28905 42df47b22465972999a96b1347cec6b3 218 SUPERFAMILY SSF56784 2 206 3.76E-33 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS28905 42df47b22465972999a96b1347cec6b3 218 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 3 188 1.0E-23 T 29-03-2018 THSYN_RS05135 f8860af51412bbcfc6f016d1ddacde49 114 Gene3D G3DSA:1.10.10.10 6 99 1.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS05135 f8860af51412bbcfc6f016d1ddacde49 114 SUPERFAMILY SSF46785 42 92 5.75E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS30060 513ce7279718c426ee00b4bc00eb52ae 732 Gene3D G3DSA:3.40.50.300 60 448 1.3E-16 T 29-03-2018 THSYN_RS30060 513ce7279718c426ee00b4bc00eb52ae 732 Gene3D G3DSA:3.40.50.300 495 667 1.3E-29 T 29-03-2018 THSYN_RS30060 513ce7279718c426ee00b4bc00eb52ae 732 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 290 411 1.4E-9 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS30060 513ce7279718c426ee00b4bc00eb52ae 732 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 530 652 3.9E-28 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS30060 513ce7279718c426ee00b4bc00eb52ae 732 SUPERFAMILY SSF52540 522 699 1.61E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30060 513ce7279718c426ee00b4bc00eb52ae 732 SMART SM00382 526 655 9.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS30060 513ce7279718c426ee00b4bc00eb52ae 732 SMART SM00382 285 417 1.6E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS30060 513ce7279718c426ee00b4bc00eb52ae 732 SUPERFAMILY SSF52540 270 468 2.05E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00550 3e7492ca7d48dddc084d948a027ca23d 125 Gene3D G3DSA:3.10.450.50 2 115 2.0E-12 T 29-03-2018 THSYN_RS00550 3e7492ca7d48dddc084d948a027ca23d 125 SUPERFAMILY SSF54427 4 121 8.05E-12 T 29-03-2018 IPR032710 NTF2-like domain THSYN_RS26545 5f373c47ccc2ecd1580bf9f1668c8551 66 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 4 66 2.8E-29 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 THSYN_RS26545 5f373c47ccc2ecd1580bf9f1668c8551 66 Pfam PF04384 Iron-sulphur cluster assembly 3 66 1.9E-26 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 THSYN_RS26545 5f373c47ccc2ecd1580bf9f1668c8551 66 SUPERFAMILY SSF140319 3 64 2.48E-22 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 THSYN_RS26545 5f373c47ccc2ecd1580bf9f1668c8551 66 Gene3D G3DSA:1.10.10.600 2 64 2.7E-27 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 THSYN_RS26545 5f373c47ccc2ecd1580bf9f1668c8551 66 PIRSF PIRSF039003 3 66 4.6E-29 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 THSYN_RS06695 8a0581ff69c2ea5da781a27997dd249e 40 Gene3D G3DSA:1.10.10.60 1 39 1.2E-10 T 29-03-2018 THSYN_RS06695 8a0581ff69c2ea5da781a27997dd249e 40 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 3 18 3.3E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THSYN_RS06695 8a0581ff69c2ea5da781a27997dd249e 40 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 18 34 3.3E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THSYN_RS06695 8a0581ff69c2ea5da781a27997dd249e 40 SUPERFAMILY SSF46689 2 38 8.51E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS06695 8a0581ff69c2ea5da781a27997dd249e 40 Pfam PF12833 Helix-turn-helix domain 2 35 2.6E-8 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THSYN_RS22940 50791882d8d36a3bc86afccdbd7a08ae 207 SUPERFAMILY SSF54631 67 185 2.15E-29 T 29-03-2018 THSYN_RS22940 50791882d8d36a3bc86afccdbd7a08ae 207 SMART SM00116 76 124 2.2E-9 T 29-03-2018 IPR000644 CBS domain THSYN_RS22940 50791882d8d36a3bc86afccdbd7a08ae 207 SMART SM00116 142 189 0.056 T 29-03-2018 IPR000644 CBS domain THSYN_RS22940 50791882d8d36a3bc86afccdbd7a08ae 207 Pfam PF00571 CBS domain 136 184 2.0E-8 T 29-03-2018 IPR000644 CBS domain THSYN_RS22940 50791882d8d36a3bc86afccdbd7a08ae 207 Pfam PF00571 CBS domain 76 123 1.8E-9 T 29-03-2018 IPR000644 CBS domain THSYN_RS22940 50791882d8d36a3bc86afccdbd7a08ae 207 Gene3D G3DSA:3.10.580.10 59 186 9.9E-26 T 29-03-2018 THSYN_RS17275 7256a3091d2e9639e13eaad8659a2e52 192 SUPERFAMILY SSF52980 2 184 5.09E-23 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS17275 7256a3091d2e9639e13eaad8659a2e52 192 Gene3D G3DSA:3.90.1570.10 2 189 6.7E-42 T 29-03-2018 THSYN_RS17275 7256a3091d2e9639e13eaad8659a2e52 192 Pfam PF05685 Putative restriction endonuclease 11 170 1.5E-29 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS09110 9070d332cdb230de45f82cd37ab2ce6d 297 Pfam PF13714 Phosphoenolpyruvate phosphomutase 19 261 3.8E-45 T 29-03-2018 THSYN_RS09110 9070d332cdb230de45f82cd37ab2ce6d 297 Gene3D G3DSA:3.20.20.60 9 296 9.9E-84 T 29-03-2018 THSYN_RS09110 9070d332cdb230de45f82cd37ab2ce6d 297 SUPERFAMILY SSF51621 17 291 1.35E-84 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 Gene3D G3DSA:4.10.480.10 255 332 4.8E-30 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 72 227 7.7E-30 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 247 328 1.3E-27 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 17 381 1.2E-128 T 29-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 PIRSF PIRSF000310 15 385 5.4E-127 T 29-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 252 270 5.4E-61 T 29-03-2018 THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 234 251 5.4E-61 T 29-03-2018 THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 57 79 5.4E-61 T 29-03-2018 THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 208 231 5.4E-61 T 29-03-2018 THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 80 104 5.4E-61 T 29-03-2018 THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 276 302 5.4E-61 T 29-03-2018 THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 126 149 5.4E-61 T 29-03-2018 THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 Gene3D G3DSA:3.40.50.700 56 254 2.4E-50 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS18990 1b33e33abf42767712150622e0c2c755 397 SUPERFAMILY SSF56770 60 327 6.06E-84 T 29-03-2018 THSYN_RS14870 8783493719ed4e812a23f46207a4de3e 453 SUPERFAMILY SSF54001 39 123 1.9E-12 T 29-03-2018 THSYN_RS14870 8783493719ed4e812a23f46207a4de3e 453 SUPERFAMILY SSF54001 175 261 1.9E-12 T 29-03-2018 THSYN_RS14870 8783493719ed4e812a23f46207a4de3e 453 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 47 58 - T 29-03-2018 IPR000169 Cysteine peptidase, cysteine active site THSYN_RS14870 8783493719ed4e812a23f46207a4de3e 453 Gene3D G3DSA:3.90.70.10 30 368 8.2E-11 T 29-03-2018 THSYN_RS21165 046e8aabba9c7a08c1a62013e9a4a303 611 SMART SM00910 511 609 2.6E-18 T 29-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 THSYN_RS21165 046e8aabba9c7a08c1a62013e9a4a303 611 Pfam PF08797 HIRAN domain 520 584 4.7E-11 T 29-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 THSYN_RS21165 046e8aabba9c7a08c1a62013e9a4a303 611 Pfam PF14284 PcfJ-like protein 376 440 3.4E-8 T 29-03-2018 IPR025586 PcfJ-like protein THSYN_RS06720 c770d412f010dbb4bb370d229c7e1685 133 Pfam PF00085 Thioredoxin 3 100 1.1E-25 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 THSYN_RS06720 c770d412f010dbb4bb370d229c7e1685 133 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THSYN_RS06720 c770d412f010dbb4bb370d229c7e1685 133 TIGRFAM TIGR01068 thioredoxin: thioredoxin 11 102 5.2E-30 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THSYN_RS06720 c770d412f010dbb4bb370d229c7e1685 133 SUPERFAMILY SSF52833 2 103 7.65E-32 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS06720 c770d412f010dbb4bb370d229c7e1685 133 Gene3D G3DSA:3.40.30.10 1 128 9.0E-32 T 29-03-2018 THSYN_RS06720 c770d412f010dbb4bb370d229c7e1685 133 PRINTS PR00421 Thioredoxin family signature 29 38 4.3E-9 T 29-03-2018 THSYN_RS06720 c770d412f010dbb4bb370d229c7e1685 133 PRINTS PR00421 Thioredoxin family signature 21 29 4.3E-9 T 29-03-2018 THSYN_RS06720 c770d412f010dbb4bb370d229c7e1685 133 PRINTS PR00421 Thioredoxin family signature 68 79 4.3E-9 T 29-03-2018 THSYN_RS12630 d684f6b4a98c895931db991049d1847e 564 Gene3D G3DSA:1.25.40.10 408 563 1.0E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS12630 d684f6b4a98c895931db991049d1847e 564 Gene3D G3DSA:3.30.70.100 275 342 0.15 T 29-03-2018 THSYN_RS12630 d684f6b4a98c895931db991049d1847e 564 SUPERFAMILY SSF48452 223 367 1.21E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS12630 d684f6b4a98c895931db991049d1847e 564 SUPERFAMILY SSF48452 334 483 2.2E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS12630 d684f6b4a98c895931db991049d1847e 564 Gene3D G3DSA:1.10.150.200 193 274 5.5E-4 T 29-03-2018 THSYN_RS12630 d684f6b4a98c895931db991049d1847e 564 Gene3D G3DSA:1.10.150.200 343 407 1.1E-4 T 29-03-2018 THSYN_RS01325 a39c1a0a12b179b31341af57d512cd27 158 SUPERFAMILY SSF88723 1 132 5.76E-7 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS01325 a39c1a0a12b179b31341af57d512cd27 158 Gene3D G3DSA:3.40.50.1010 4 145 6.1E-13 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS00030 0cfb82277d554ae526a290fde147363f 186 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 5 149 4.1E-29 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 THSYN_RS00030 0cfb82277d554ae526a290fde147363f 186 Pfam PF13242 HAD-hyrolase-like 102 174 1.6E-8 T 29-03-2018 THSYN_RS00030 0cfb82277d554ae526a290fde147363f 186 PIRSF PIRSF004682 1 183 4.7E-47 T 29-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 THSYN_RS00030 0cfb82277d554ae526a290fde147363f 186 SUPERFAMILY SSF56784 5 179 1.48E-37 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS00030 0cfb82277d554ae526a290fde147363f 186 Gene3D G3DSA:3.40.50.1000 5 183 3.2E-23 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS00030 0cfb82277d554ae526a290fde147363f 186 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 7 147 6.9E-39 T 29-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 THSYN_RS00035 3fd0408187c027a6e46a1417d989896a 699 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 549 1.3E-196 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00035 3fd0408187c027a6e46a1417d989896a 699 Pfam PF05746 DALR anticodon binding domain 581 680 3.8E-9 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 THSYN_RS00035 3fd0408187c027a6e46a1417d989896a 699 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 245 260 1.5E-33 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00035 3fd0408187c027a6e46a1417d989896a 699 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 1.5E-33 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00035 3fd0408187c027a6e46a1417d989896a 699 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 1.5E-33 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00035 3fd0408187c027a6e46a1417d989896a 699 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 317 333 1.5E-33 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00035 3fd0408187c027a6e46a1417d989896a 699 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 393 412 1.5E-33 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00035 3fd0408187c027a6e46a1417d989896a 699 Gene3D G3DSA:1.10.730.10 574 692 3.4E-12 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS00035 3fd0408187c027a6e46a1417d989896a 699 Gene3D G3DSA:1.10.3210.10 271 512 1.6E-7 T 29-03-2018 THSYN_RS00035 3fd0408187c027a6e46a1417d989896a 699 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 690 7.4E-213 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS00035 3fd0408187c027a6e46a1417d989896a 699 SUPERFAMILY SSF109604 341 485 4.93E-17 T 29-03-2018 THSYN_RS00035 3fd0408187c027a6e46a1417d989896a 699 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 689 24.054 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THSYN_RS28200 c6c7a20f61d9b772495fc36489ffe5d0 342 Pfam PF08496 Peptidase family S49 N-terminal 3 151 1.9E-43 T 29-03-2018 IPR013703 Peptidase S49, N-terminal proteobacteria GO:0004252|GO:0005886 THSYN_RS28200 c6c7a20f61d9b772495fc36489ffe5d0 342 Pfam PF01343 Peptidase family S49 155 300 2.1E-41 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 THSYN_RS28200 c6c7a20f61d9b772495fc36489ffe5d0 342 SUPERFAMILY SSF52096 92 202 8.81E-26 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS28200 c6c7a20f61d9b772495fc36489ffe5d0 342 SUPERFAMILY SSF52096 233 292 8.81E-26 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS28200 c6c7a20f61d9b772495fc36489ffe5d0 342 Gene3D G3DSA:3.90.226.10 48 300 3.3E-28 T 29-03-2018 THSYN_RS03525 71a4fd9177993ad445a98f188220fd71 96 Hamap MF_00910 Cell division protein FtsL [ftsL]. 3 88 14.282 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 THSYN_RS03525 71a4fd9177993ad445a98f188220fd71 96 Pfam PF04999 Cell division protein FtsL 8 88 3.2E-19 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 THSYN_RS03525 71a4fd9177993ad445a98f188220fd71 96 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 9 83 2.5E-18 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 THSYN_RS17130 61c3d0dff0e462c4b0c5fae4b5d2b373 306 Pfam PF12784 PD-(D/E)XK nuclease family transposase 10 241 6.6E-29 T 29-03-2018 THSYN_RS17130 61c3d0dff0e462c4b0c5fae4b5d2b373 306 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 10 302 1.5E-22 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA THSYN_RS17130 61c3d0dff0e462c4b0c5fae4b5d2b373 306 Gene3D G3DSA:1.10.10.60 250 302 2.9E-6 T 29-03-2018 THSYN_RS30975 aa4cf6509097ddc43687e04e05308aa4 343 Gene3D G3DSA:3.40.190.10 206 343 1.3E-16 T 29-03-2018 THSYN_RS30975 aa4cf6509097ddc43687e04e05308aa4 343 Gene3D G3DSA:3.40.190.10 29 192 8.2E-33 T 29-03-2018 THSYN_RS30975 aa4cf6509097ddc43687e04e05308aa4 343 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 30 341 4.4E-107 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 THSYN_RS30975 aa4cf6509097ddc43687e04e05308aa4 343 PIRSF PIRSF002756 4 343 1.0E-106 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 THSYN_RS30975 aa4cf6509097ddc43687e04e05308aa4 343 Pfam PF12849 PBP superfamily domain 24 314 1.7E-54 T 29-03-2018 IPR024370 PBP domain THSYN_RS30975 aa4cf6509097ddc43687e04e05308aa4 343 SUPERFAMILY SSF53850 30 341 1.59E-88 T 29-03-2018 THSYN_RS30280 c074174d243b272a5694ed5deee7b24c 388 Pfam PF01609 Transposase DDE domain 123 333 4.9E-27 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS30280 c074174d243b272a5694ed5deee7b24c 388 SUPERFAMILY SSF53098 95 342 8.34E-30 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS30280 c074174d243b272a5694ed5deee7b24c 388 Gene3D G3DSA:3.90.350.10 120 313 5.8E-24 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS30280 c074174d243b272a5694ed5deee7b24c 388 Pfam PF14294 Domain of unknown function (DUF4372) 4 76 8.9E-32 T 29-03-2018 IPR025399 Domain of unknown function DUF4372 THSYN_RS30210 c074174d243b272a5694ed5deee7b24c 388 Pfam PF01609 Transposase DDE domain 123 333 4.9E-27 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS30210 c074174d243b272a5694ed5deee7b24c 388 SUPERFAMILY SSF53098 95 342 8.34E-30 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS30210 c074174d243b272a5694ed5deee7b24c 388 Gene3D G3DSA:3.90.350.10 120 313 5.8E-24 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS30210 c074174d243b272a5694ed5deee7b24c 388 Pfam PF14294 Domain of unknown function (DUF4372) 4 76 8.9E-32 T 29-03-2018 IPR025399 Domain of unknown function DUF4372 THSYN_RS05515 526bc4a25d44844aebb953cdb7f1caaa 330 SUPERFAMILY SSF53448 85 301 6.94E-49 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS05515 526bc4a25d44844aebb953cdb7f1caaa 330 Pfam PF00535 Glycosyl transferase family 2 88 205 4.1E-28 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS05515 526bc4a25d44844aebb953cdb7f1caaa 330 Gene3D G3DSA:3.90.550.10 85 295 2.9E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS19980 d0155bfe04a63fd2777d00a12ae1c53e 113 SMART SM01248 28 109 1.8E-48 T 29-03-2018 IPR011649 KaiB domain GO:0048511 THSYN_RS19980 d0155bfe04a63fd2777d00a12ae1c53e 113 Pfam PF07689 KaiB domain 28 108 3.0E-25 T 29-03-2018 IPR011649 KaiB domain GO:0048511 THSYN_RS19980 d0155bfe04a63fd2777d00a12ae1c53e 113 Gene3D G3DSA:3.40.30.10 24 104 1.1E-14 T 29-03-2018 THSYN_RS19980 d0155bfe04a63fd2777d00a12ae1c53e 113 SUPERFAMILY SSF52833 20 110 2.74E-29 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS15240 f790686fba899cf13ea5968ef67b09b9 72 Pfam PF11127 Protein of unknown function (DUF2892) 7 65 2.8E-18 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 THSYN_RS18515 cfe9a1052391ebe901e3292c91c26dc1 226 Pfam PF09335 SNARE associated Golgi protein 67 181 2.3E-22 T 29-03-2018 IPR032816 SNARE associated Golgi protein THSYN_RS05790 156eafb58aca2bd93322a0b53719c483 215 Gene3D G3DSA:3.40.50.150 53 192 1.9E-5 T 29-03-2018 THSYN_RS05790 156eafb58aca2bd93322a0b53719c483 215 SUPERFAMILY SSF53335 29 189 3.62E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS18325 98407971b1ee1ce7fce8ddac9ff26db8 92 Pfam PF04221 RelB antitoxin 4 74 1.1E-21 T 29-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ THSYN_RS18325 98407971b1ee1ce7fce8ddac9ff26db8 92 PIRSF PIRSF003108 1 90 1.3E-28 T 29-03-2018 IPR026262 Antitoxin DinJ GO:0000986|GO:0015643|GO:0044010 THSYN_RS18325 98407971b1ee1ce7fce8ddac9ff26db8 92 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 1 86 1.6E-25 T 29-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ THSYN_RS23115 380f911335ba54b8377ab88227612178 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.9E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS23115 380f911335ba54b8377ab88227612178 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.9E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS23115 380f911335ba54b8377ab88227612178 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.9E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS23115 380f911335ba54b8377ab88227612178 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 187 0.0027 T 29-03-2018 THSYN_RS23115 380f911335ba54b8377ab88227612178 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THSYN_RS23115 380f911335ba54b8377ab88227612178 252 SUPERFAMILY SSF51735 8 251 3.78E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS23115 380f911335ba54b8377ab88227612178 252 Gene3D G3DSA:3.40.50.720 6 252 1.6E-61 T 29-03-2018 THSYN_RS23115 380f911335ba54b8377ab88227612178 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 250 1.5E-53 T 29-03-2018 THSYN_RS23115 380f911335ba54b8377ab88227612178 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.8E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS23115 380f911335ba54b8377ab88227612178 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 4.8E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS23115 380f911335ba54b8377ab88227612178 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.8E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS23115 380f911335ba54b8377ab88227612178 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.8E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS23115 380f911335ba54b8377ab88227612178 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 4.8E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS10810 0c71f14ac69837aa27795d5c50f776bb 180 Gene3D G3DSA:1.25.40.10 22 70 0.097 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS10810 0c71f14ac69837aa27795d5c50f776bb 180 Gene3D G3DSA:1.25.40.10 71 171 0.0027 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS13320 68d0b02792fbeae9900e1e682902af9a 574 Pfam PF10592 AIPR protein 239 518 1.8E-60 T 29-03-2018 IPR018891 Abortive bacteriophage infection, resistance THSYN_RS07145 4be44812b0e317cc298ea3d30f320c5d 196 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 184 2.1E-59 T 29-03-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 THSYN_RS07145 4be44812b0e317cc298ea3d30f320c5d 196 SUPERFAMILY SSF53323 1 185 5.36E-47 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 THSYN_RS07145 4be44812b0e317cc298ea3d30f320c5d 196 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 181 2.1E-35 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 THSYN_RS07145 4be44812b0e317cc298ea3d30f320c5d 196 Gene3D G3DSA:3.40.920.10 1 187 9.4E-49 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 THSYN_RS30455 0373c158600b74335754c90fed6cd77a 222 Pfam PF14348 Domain of unknown function (DUF4400) 43 219 1.7E-23 T 29-03-2018 IPR022266 Integrating conjugative element protein, PFL4697-type THSYN_RS07630 72d24305c5dbda6a257b597e5206a352 328 Gene3D G3DSA:1.10.260.40 9 95 1.1E-7 T 29-03-2018 THSYN_RS07630 72d24305c5dbda6a257b597e5206a352 328 Pfam PF13464 Domain of unknown function (DUF4115) 249 321 4.0E-21 T 29-03-2018 IPR025194 Domain of unknown function DUF4115 THSYN_RS07630 72d24305c5dbda6a257b597e5206a352 328 Pfam PF13413 Helix-turn-helix domain 24 84 1.4E-22 T 29-03-2018 THSYN_RS00105 cf0b0d38bf2d26754728014482487033 1055 Pfam PF04851 Type III restriction enzyme, res subunit 288 461 1.9E-17 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS00105 cf0b0d38bf2d26754728014482487033 1055 SMART SM00487 284 486 2.0E-9 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS00105 cf0b0d38bf2d26754728014482487033 1055 Gene3D G3DSA:3.40.50.300 114 480 1.6E-20 T 29-03-2018 THSYN_RS00105 cf0b0d38bf2d26754728014482487033 1055 SUPERFAMILY SSF52540 267 503 2.0E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00105 cf0b0d38bf2d26754728014482487033 1055 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 27 212 6.3E-20 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THSYN_RS00105 cf0b0d38bf2d26754728014482487033 1055 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 26 734 3.6E-135 T 29-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 THSYN_RS04865 2d3a4f674e2998a304c5734f1caddec8 185 Pfam PF00578 AhpC/TSA family 13 127 2.2E-15 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THSYN_RS04865 2d3a4f674e2998a304c5734f1caddec8 185 Gene3D G3DSA:3.40.30.10 2 185 1.5E-28 T 29-03-2018 THSYN_RS04865 2d3a4f674e2998a304c5734f1caddec8 185 SUPERFAMILY SSF52833 6 184 9.42E-45 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS16340 f4c403f00e62c78b4bbed632c9715a65 232 Pfam PF13391 HNH endonuclease 119 172 7.3E-9 T 29-03-2018 IPR003615 HNH nuclease THSYN_RS31700 8a9841312851aa023d04af8a81d5b640 168 Pfam PF07284 2-vinyl bacteriochlorophyllide hydratase (BCHF) 4 141 7.6E-65 T 29-03-2018 IPR009905 2-vinyl bacteriochlorophyllide hydratase GO:0016836|GO:0019685|GO:0030494 THSYN_RS31700 8a9841312851aa023d04af8a81d5b640 168 TIGRFAM TIGR02020 BchF: 2-vinyl bacteriochlorophyllide hydratase 3 144 5.6E-60 T 29-03-2018 IPR009905 2-vinyl bacteriochlorophyllide hydratase GO:0016836|GO:0019685|GO:0030494 THSYN_RS21575 76bcbedb808769d30a82bceb8a4b1ded 462 Gene3D G3DSA:3.40.50.1980 170 280 2.5E-35 T 29-03-2018 THSYN_RS21575 76bcbedb808769d30a82bceb8a4b1ded 462 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 37 44 - T 29-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 THSYN_RS21575 76bcbedb808769d30a82bceb8a4b1ded 462 Gene3D G3DSA:3.40.50.1980 19 164 1.1E-37 T 29-03-2018 THSYN_RS21575 76bcbedb808769d30a82bceb8a4b1ded 462 TIGRFAM TIGR01285 nifN: nitrogenase molybdenum-iron cofactor biosynthesis protein NifN 3 436 4.6E-179 T 29-03-2018 IPR005975 Nitrogenase molybdenum-iron cofactor biosynthesis protein GO:0006461|GO:0009399 THSYN_RS21575 76bcbedb808769d30a82bceb8a4b1ded 462 Gene3D G3DSA:1.20.89.10 281 349 9.8E-24 T 29-03-2018 THSYN_RS21575 76bcbedb808769d30a82bceb8a4b1ded 462 SUPERFAMILY SSF53807 7 436 1.6E-118 T 29-03-2018 THSYN_RS21575 76bcbedb808769d30a82bceb8a4b1ded 462 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 19 434 1.4E-111 T 29-03-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 THSYN_RS21575 76bcbedb808769d30a82bceb8a4b1ded 462 Gene3D G3DSA:3.40.50.1980 353 444 2.0E-14 T 29-03-2018 THSYN_RS07565 823af31d7c7fba9f6e5aa847b38c7eaa 201 Gene3D G3DSA:3.40.50.1240 1 199 1.7E-47 T 29-03-2018 IPR029033 Histidine phosphatase superfamily THSYN_RS07565 823af31d7c7fba9f6e5aa847b38c7eaa 201 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 192 7.6E-50 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THSYN_RS07565 823af31d7c7fba9f6e5aa847b38c7eaa 201 PIRSF PIRSF000709 2 197 3.0E-9 T 29-03-2018 THSYN_RS07565 823af31d7c7fba9f6e5aa847b38c7eaa 201 SMART SM00855 3 158 3.1E-20 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THSYN_RS07565 823af31d7c7fba9f6e5aa847b38c7eaa 201 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 THSYN_RS07565 823af31d7c7fba9f6e5aa847b38c7eaa 201 SUPERFAMILY SSF53254 1 189 1.16E-50 T 29-03-2018 IPR029033 Histidine phosphatase superfamily THSYN_RS11610 e14cf3f6043f948dc85b1b185a9d86b3 292 Pfam PF08241 Methyltransferase domain 51 147 1.3E-23 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THSYN_RS11610 e14cf3f6043f948dc85b1b185a9d86b3 292 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 14 264 7.4E-73 T 29-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 THSYN_RS11610 e14cf3f6043f948dc85b1b185a9d86b3 292 SUPERFAMILY SSF53335 12 249 1.49E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS11610 e14cf3f6043f948dc85b1b185a9d86b3 292 Gene3D G3DSA:3.40.50.150 31 273 5.5E-45 T 29-03-2018 THSYN_RS11610 e14cf3f6043f948dc85b1b185a9d86b3 292 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 6 265 32.993 T 29-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 THSYN_RS06305 5749f02ade022850d6cb96df0aaf86ea 247 Pfam PF01012 Electron transfer flavoprotein domain 30 207 4.3E-44 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 THSYN_RS06305 5749f02ade022850d6cb96df0aaf86ea 247 SMART SM00893 23 212 1.6E-60 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 THSYN_RS06305 5749f02ade022850d6cb96df0aaf86ea 247 PIRSF PIRSF000090 1 247 3.3E-78 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 THSYN_RS06305 5749f02ade022850d6cb96df0aaf86ea 247 Gene3D G3DSA:3.40.50.620 1 247 2.6E-79 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS06305 5749f02ade022850d6cb96df0aaf86ea 247 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 156 176 - T 29-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 THSYN_RS06305 5749f02ade022850d6cb96df0aaf86ea 247 SUPERFAMILY SSF52402 1 243 4.95E-80 T 29-03-2018 THSYN_RS09490 dd2e1cbd99ab8049116ddceceff0c87d 642 SUPERFAMILY SSF140990 407 607 4.58E-74 T 29-03-2018 THSYN_RS09490 dd2e1cbd99ab8049116ddceceff0c87d 642 SMART SM00382 189 328 1.5E-26 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS09490 dd2e1cbd99ab8049116ddceceff0c87d 642 Gene3D G3DSA:1.10.8.60 336 419 1.3E-25 T 29-03-2018 THSYN_RS09490 dd2e1cbd99ab8049116ddceceff0c87d 642 Pfam PF06480 FtsH Extracellular 8 89 1.2E-10 T 29-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 THSYN_RS09490 dd2e1cbd99ab8049116ddceceff0c87d 642 ProSitePatterns PS00674 AAA-protein family signature. 296 314 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 THSYN_RS09490 dd2e1cbd99ab8049116ddceceff0c87d 642 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 193 325 3.6E-45 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS09490 dd2e1cbd99ab8049116ddceceff0c87d 642 Gene3D G3DSA:3.40.50.300 138 335 4.0E-62 T 29-03-2018 THSYN_RS09490 dd2e1cbd99ab8049116ddceceff0c87d 642 Pfam PF01434 Peptidase family M41 387 597 2.9E-81 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 THSYN_RS09490 dd2e1cbd99ab8049116ddceceff0c87d 642 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 104 598 1.1E-232 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 THSYN_RS09490 dd2e1cbd99ab8049116ddceceff0c87d 642 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 4 610 37.002 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 THSYN_RS09490 dd2e1cbd99ab8049116ddceceff0c87d 642 SUPERFAMILY SSF52540 152 396 1.94E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04395 e2b95a5018a14824468ef862bfe27851 338 Pfam PF01180 Dihydroorotate dehydrogenase 84 292 4.8E-9 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 THSYN_RS04395 e2b95a5018a14824468ef862bfe27851 338 PIRSF PIRSF000164 1 309 1.5E-38 T 29-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 THSYN_RS04395 e2b95a5018a14824468ef862bfe27851 338 SUPERFAMILY SSF51395 1 307 4.79E-54 T 29-03-2018 THSYN_RS04395 e2b95a5018a14824468ef862bfe27851 338 Gene3D G3DSA:3.20.20.70 1 323 6.9E-39 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS28040 451b9045bee04cb5bb8aee44dccc49ad 272 SUPERFAMILY SSF52200 3 107 7.98E-17 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS28040 451b9045bee04cb5bb8aee44dccc49ad 272 Gene3D G3DSA:3.40.50.10140 1 163 1.1E-17 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS28040 451b9045bee04cb5bb8aee44dccc49ad 272 Pfam PF13676 TIR domain 4 102 2.2E-16 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS28040 451b9045bee04cb5bb8aee44dccc49ad 272 SMART SM00255 1 139 9.9E-4 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS04085 e966bdc4ce284911d0783b38fa1479cd 116 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 29.469 T 29-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 THSYN_RS04085 e966bdc4ce284911d0783b38fa1479cd 116 SUPERFAMILY SSF47729 1 91 1.07E-29 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS04085 e966bdc4ce284911d0783b38fa1479cd 116 Pfam PF00216 Bacterial DNA-binding protein 1 91 6.7E-29 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS04085 e966bdc4ce284911d0783b38fa1479cd 116 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 92 9.1E-44 T 29-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 THSYN_RS04085 e966bdc4ce284911d0783b38fa1479cd 116 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 THSYN_RS04085 e966bdc4ce284911d0783b38fa1479cd 116 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 3.5E-18 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS04085 e966bdc4ce284911d0783b38fa1479cd 116 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 3.5E-18 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS04085 e966bdc4ce284911d0783b38fa1479cd 116 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 3.5E-18 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS04085 e966bdc4ce284911d0783b38fa1479cd 116 SMART SM00411 1 91 5.7E-41 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS04085 e966bdc4ce284911d0783b38fa1479cd 116 Gene3D G3DSA:4.10.520.10 1 98 1.0E-29 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS07585 20bdd209542360ca4ac02af7348d1658 230 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 5 222 2.0E-79 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07585 20bdd209542360ca4ac02af7348d1658 230 Gene3D G3DSA:3.10.20.30 1 99 4.5E-31 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS07585 20bdd209542360ca4ac02af7348d1658 230 Pfam PF13534 4Fe-4S dicluster domain 140 213 6.8E-11 T 29-03-2018 THSYN_RS07585 20bdd209542360ca4ac02af7348d1658 230 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 141 152 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS07585 20bdd209542360ca4ac02af7348d1658 230 SUPERFAMILY SSF46548 100 229 1.1E-37 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS07585 20bdd209542360ca4ac02af7348d1658 230 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 3 104 4.4E-30 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 THSYN_RS07585 20bdd209542360ca4ac02af7348d1658 230 SUPERFAMILY SSF54292 2 99 7.21E-27 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS07585 20bdd209542360ca4ac02af7348d1658 230 Gene3D G3DSA:1.10.1060.10 100 229 2.2E-29 T 29-03-2018 THSYN_RS11220 833c69c50a94e418c7eee900d92f5bab 122 Gene3D G3DSA:4.10.520.10 24 115 1.0E-16 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS11220 833c69c50a94e418c7eee900d92f5bab 122 SMART SM00411 26 114 9.5E-13 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS11220 833c69c50a94e418c7eee900d92f5bab 122 Pfam PF00216 Bacterial DNA-binding protein 26 110 2.0E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS11220 833c69c50a94e418c7eee900d92f5bab 122 SUPERFAMILY SSF47729 26 112 1.47E-15 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS25210 46773975405f1f488afc37be73e62b51 63 Pfam PF05635 23S rRNA-intervening sequence protein 6 57 4.4E-21 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS25210 46773975405f1f488afc37be73e62b51 63 Gene3D G3DSA:1.20.1440.60 1 62 3.4E-20 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS25210 46773975405f1f488afc37be73e62b51 63 SUPERFAMILY SSF158446 3 59 3.14E-20 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS25210 46773975405f1f488afc37be73e62b51 63 TIGRFAM TIGR02436 TIGR02436: four helix bundle protein 9 58 4.8E-19 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS28365 b7a919522322349e026152918e2195a7 464 PIRSF PIRSF000204 3 461 1.8E-198 T 29-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 THSYN_RS28365 b7a919522322349e026152918e2195a7 464 Gene3D G3DSA:3.40.50.1220 286 460 1.4E-81 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS28365 b7a919522322349e026152918e2195a7 464 SUPERFAMILY SSF52467 288 461 7.94E-71 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS28365 b7a919522322349e026152918e2195a7 464 Pfam PF02233 NAD(P) transhydrogenase beta subunit 9 457 1.1E-192 T 29-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 THSYN_RS19460 3ad9372561fe3abd3bdc9ed0cf53db91 465 Gene3D G3DSA:1.10.10.10 369 458 1.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19460 3ad9372561fe3abd3bdc9ed0cf53db91 465 SUPERFAMILY SSF46785 378 452 1.03E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19460 3ad9372561fe3abd3bdc9ed0cf53db91 465 Pfam PF13191 AAA ATPase domain 81 225 1.7E-12 T 29-03-2018 THSYN_RS19460 3ad9372561fe3abd3bdc9ed0cf53db91 465 SUPERFAMILY SSF52540 252 365 1.14E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19460 3ad9372561fe3abd3bdc9ed0cf53db91 465 SUPERFAMILY SSF52540 82 165 1.14E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19460 3ad9372561fe3abd3bdc9ed0cf53db91 465 SUPERFAMILY SSF52540 209 225 1.14E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19460 3ad9372561fe3abd3bdc9ed0cf53db91 465 Gene3D G3DSA:3.40.50.300 61 249 3.0E-10 T 29-03-2018 THSYN_RS13645 db58285383020bd02d0907ca14b29c2b 199 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 24 163 1.5E-15 T 29-03-2018 IPR013362 Pilus modification type IV, PilV THSYN_RS13645 db58285383020bd02d0907ca14b29c2b 199 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 23 43 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS13645 db58285383020bd02d0907ca14b29c2b 199 Pfam PF07963 Prokaryotic N-terminal methylation motif 19 44 5.1E-6 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 SUPERFAMILY SSF54791 557 642 5.69E-23 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 696 30.218 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 Pfam PF01138 3' exoribonuclease family, domain 1 16 145 4.5E-20 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 Pfam PF01138 3' exoribonuclease family, domain 1 327 459 3.4E-21 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 SUPERFAMILY SSF46915 233 329 9.81E-17 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 Gene3D G3DSA:3.30.300.20 532 599 3.1E-15 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 SUPERFAMILY SSF55666 146 236 1.96E-25 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 Pfam PF00575 S1 RNA binding domain 622 693 3.8E-20 T 29-03-2018 IPR003029 S1 domain GO:0003676 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 Pfam PF03725 3' exoribonuclease family, domain 2 148 212 2.1E-4 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 Pfam PF03725 3' exoribonuclease family, domain 2 463 530 3.3E-5 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 PIRSF PIRSF005499 4 698 8.7E-286 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 694 0.0 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 Gene3D G3DSA:2.40.50.140 614 698 1.6E-25 T 29-03-2018 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 SUPERFAMILY SSF55666 453 552 1.42E-27 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 SMART SM00316 623 693 3.6E-26 T 29-03-2018 IPR022967 RNA-binding domain, S1 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 243 323 3.7E-16 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 SUPERFAMILY SSF50249 621 698 3.13E-21 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 Pfam PF00013 KH domain 559 616 7.9E-10 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 SMART SM00322 555 620 1.1E-11 T 29-03-2018 IPR004087 K Homology domain GO:0003676 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 Gene3D G3DSA:3.30.230.70 15 252 7.3E-43 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 SUPERFAMILY SSF54211 304 495 6.58E-47 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 SUPERFAMILY SSF54211 5 145 7.59E-49 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 Gene3D G3DSA:3.30.230.70 320 531 2.5E-57 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THSYN_RS09420 7775b07ef185fbb9942f5d8e3e1388e6 699 Gene3D G3DSA:1.10.10.400 253 319 2.7E-16 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THSYN_RS11915 dc76d25d0af637f01b1b2e3e780afe1b 327 Gene3D G3DSA:3.40.50.300 41 210 1.5E-19 T 29-03-2018 THSYN_RS11915 dc76d25d0af637f01b1b2e3e780afe1b 327 SMART SM00382 47 216 4.0E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS11915 dc76d25d0af637f01b1b2e3e780afe1b 327 TIGRFAM TIGR02640 gas_vesic_GvpN: gas vesicle protein GvpN 28 288 6.2E-101 T 29-03-2018 IPR013462 Gas vesicle protein GvpN GO:0000166|GO:0005524|GO:0031411|GO:0031412 THSYN_RS11915 dc76d25d0af637f01b1b2e3e780afe1b 327 SUPERFAMILY SSF52540 40 294 3.94E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11915 dc76d25d0af637f01b1b2e3e780afe1b 327 Pfam PF07728 AAA domain (dynein-related subfamily) 51 205 1.1E-15 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THSYN_RS04710 44fbc3c1f7cb1b6505d2c1263900d8ee 547 Pfam PF09820 Predicted AAA-ATPase 9 272 3.6E-87 T 29-03-2018 IPR018631 AAA-ATPase-like domain THSYN_RS04710 44fbc3c1f7cb1b6505d2c1263900d8ee 547 Pfam PF08011 PD-(D/E)XK nuclease superfamily 420 536 6.9E-18 T 29-03-2018 IPR012547 PD-(D/E)XK nuclease superfamily 9 THSYN_RS12235 aaf040e871a3a7527c51c35a1eb1ebfa 230 Gene3D G3DSA:2.60.120.380 18 129 6.8E-10 T 29-03-2018 THSYN_RS23125 da185b5f0557d0d664096ff569256a97 75 Gene3D G3DSA:1.10.1200.10 3 75 2.0E-11 T 29-03-2018 THSYN_RS23125 da185b5f0557d0d664096ff569256a97 75 Pfam PF00550 Phosphopantetheine attachment site 5 70 1.6E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain THSYN_RS23125 da185b5f0557d0d664096ff569256a97 75 SUPERFAMILY SSF47336 6 74 4.84E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain THSYN_RS13730 359fc9f2f7060af6184170e5f95ffac5 187 Pfam PF03167 Uracil DNA glycosylase superfamily 12 161 2.8E-25 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THSYN_RS13730 359fc9f2f7060af6184170e5f95ffac5 187 SMART SM00986 5 171 3.4E-15 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THSYN_RS13730 359fc9f2f7060af6184170e5f95ffac5 187 SMART SM00987 5 171 3.4E-15 T 29-03-2018 THSYN_RS13730 359fc9f2f7060af6184170e5f95ffac5 187 Gene3D G3DSA:3.40.470.10 3 169 6.4E-29 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THSYN_RS13730 359fc9f2f7060af6184170e5f95ffac5 187 SUPERFAMILY SSF52141 6 158 6.21E-29 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THSYN_RS06610 227d08327d7704753a084c58d0f7bc7c 485 Pfam PF11066 Protein of unknown function (DUF2867) 340 468 1.0E-22 T 29-03-2018 IPR021295 Protein of unknown function DUF2867 THSYN_RS06610 227d08327d7704753a084c58d0f7bc7c 485 Gene3D G3DSA:3.40.50.720 4 311 8.9E-25 T 29-03-2018 THSYN_RS06610 227d08327d7704753a084c58d0f7bc7c 485 Gene3D G3DSA:3.30.530.20 330 484 2.5E-15 T 29-03-2018 IPR023393 START-like domain THSYN_RS06610 227d08327d7704753a084c58d0f7bc7c 485 SUPERFAMILY SSF55961 340 472 3.02E-15 T 29-03-2018 THSYN_RS06610 227d08327d7704753a084c58d0f7bc7c 485 SUPERFAMILY SSF51735 11 297 2.84E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS06610 227d08327d7704753a084c58d0f7bc7c 485 Pfam PF13460 NAD(P)H-binding 14 118 4.0E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS19670 4aa71065f8b98266e47d14efd6ffa9b6 166 SUPERFAMILY SSF52821 31 163 5.63E-20 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS19670 4aa71065f8b98266e47d14efd6ffa9b6 166 Gene3D G3DSA:3.40.250.10 39 165 7.9E-19 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS19670 4aa71065f8b98266e47d14efd6ffa9b6 166 Pfam PF00581 Rhodanese-like domain 54 145 7.0E-9 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS19670 4aa71065f8b98266e47d14efd6ffa9b6 166 SMART SM00450 48 153 1.0E-4 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS24845 c54c5ab5cbebddc7e0509c6f71312d82 133 Gene3D G3DSA:3.40.50.1010 1 133 8.9E-25 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS24845 c54c5ab5cbebddc7e0509c6f71312d82 133 Pfam PF01850 PIN domain 3 124 4.5E-17 T 29-03-2018 IPR002716 PIN domain THSYN_RS24845 c54c5ab5cbebddc7e0509c6f71312d82 133 SUPERFAMILY SSF88723 1 131 1.68E-33 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS24845 c54c5ab5cbebddc7e0509c6f71312d82 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 130 10.71 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS06760 7f9120610a7c4fde3ad0ad158aa00bf7 134 Pfam PF01850 PIN domain 5 129 2.6E-9 T 29-03-2018 IPR002716 PIN domain THSYN_RS06760 7f9120610a7c4fde3ad0ad158aa00bf7 134 SUPERFAMILY SSF88723 1 129 2.13E-22 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS06760 7f9120610a7c4fde3ad0ad158aa00bf7 134 Gene3D G3DSA:3.40.50.1010 2 131 3.8E-13 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS30635 92355dc5381c5bcde68d381d968d99f4 112 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 6 105 6.6E-23 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 THSYN_RS30635 92355dc5381c5bcde68d381d968d99f4 112 SUPERFAMILY SSF52091 2 108 5.1E-27 T 29-03-2018 IPR002645 STAS domain THSYN_RS30635 92355dc5381c5bcde68d381d968d99f4 112 Gene3D G3DSA:3.30.750.24 1 112 1.3E-21 T 29-03-2018 IPR002645 STAS domain THSYN_RS30635 92355dc5381c5bcde68d381d968d99f4 112 Pfam PF01740 STAS domain 8 106 3.0E-16 T 29-03-2018 IPR002645 STAS domain THSYN_RS22600 241b2db8ea4554b48a399076d6da8884 212 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 138 148 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THSYN_RS22600 241b2db8ea4554b48a399076d6da8884 212 Gene3D G3DSA:1.10.286.10 31 79 6.4E-20 T 29-03-2018 THSYN_RS22600 241b2db8ea4554b48a399076d6da8884 212 SUPERFAMILY SSF55620 22 211 6.0E-80 T 29-03-2018 THSYN_RS22600 241b2db8ea4554b48a399076d6da8884 212 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 29 211 39.188 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THSYN_RS22600 241b2db8ea4554b48a399076d6da8884 212 Pfam PF01227 GTP cyclohydrolase I 35 210 8.5E-76 T 29-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THSYN_RS22600 241b2db8ea4554b48a399076d6da8884 212 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 90 106 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THSYN_RS22600 241b2db8ea4554b48a399076d6da8884 212 Gene3D G3DSA:3.30.1130.10 81 212 9.0E-62 T 29-03-2018 THSYN_RS22600 241b2db8ea4554b48a399076d6da8884 212 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 36 211 1.4E-76 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THSYN_RS19535 1deb0b94ef430542ae42bcfaf7ec4edf 410 Gene3D G3DSA:3.90.1150.10 258 409 5.3E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS19535 1deb0b94ef430542ae42bcfaf7ec4edf 410 Gene3D G3DSA:3.90.1150.10 11 257 4.4E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS19535 1deb0b94ef430542ae42bcfaf7ec4edf 410 Pfam PF00155 Aminotransferase class I and II 35 382 6.9E-54 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THSYN_RS19535 1deb0b94ef430542ae42bcfaf7ec4edf 410 SUPERFAMILY SSF53383 7 403 2.72E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS08935 bd50e707627114c9b2bc9bbd40226e45 246 Pfam PF01816 Leucine rich repeat variant 132 154 6.1E-6 T 29-03-2018 IPR004830 Leucine rich repeat variant THSYN_RS08935 bd50e707627114c9b2bc9bbd40226e45 246 Pfam PF01816 Leucine rich repeat variant 107 130 7.4E-7 T 29-03-2018 IPR004830 Leucine rich repeat variant THSYN_RS08935 bd50e707627114c9b2bc9bbd40226e45 246 Pfam PF01816 Leucine rich repeat variant 155 178 1.7E-5 T 29-03-2018 IPR004830 Leucine rich repeat variant THSYN_RS08935 bd50e707627114c9b2bc9bbd40226e45 246 SUPERFAMILY SSF48371 10 214 9.46E-42 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS08935 bd50e707627114c9b2bc9bbd40226e45 246 Pfam PF05484 LRV protein FeS4 cluster 8 51 1.0E-16 T 29-03-2018 IPR008665 LRV FeS4 cluster THSYN_RS08935 bd50e707627114c9b2bc9bbd40226e45 246 Gene3D G3DSA:1.25.10.10 190 239 6.4E-6 T 29-03-2018 IPR011989 Armadillo-like helical THSYN_RS08935 bd50e707627114c9b2bc9bbd40226e45 246 Gene3D G3DSA:1.25.10.10 1 189 5.9E-31 T 29-03-2018 IPR011989 Armadillo-like helical THSYN_RS11725 46970ca049df90de9dd18b91e5d0c57e 130 Pfam PF07238 PilZ domain 2 95 3.3E-13 T 29-03-2018 IPR009875 PilZ domain GO:0035438 THSYN_RS11725 46970ca049df90de9dd18b91e5d0c57e 130 SUPERFAMILY SSF141371 2 90 5.1E-7 T 29-03-2018 THSYN_RS11725 46970ca049df90de9dd18b91e5d0c57e 130 Gene3D G3DSA:2.40.10.220 1 121 1.6E-14 T 29-03-2018 THSYN_RS21045 ee7fd6c4df41961dba4ed8d7be696d05 68 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 28 6.3E-7 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THSYN_RS21835 21c5e36d165de879543d7dbde9bc8a63 744 SUPERFAMILY SSF48452 390 495 2.07E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS21835 21c5e36d165de879543d7dbde9bc8a63 744 Gene3D G3DSA:1.25.40.10 512 742 0.021 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS21835 21c5e36d165de879543d7dbde9bc8a63 744 Gene3D G3DSA:1.25.40.10 22 181 0.12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS21835 21c5e36d165de879543d7dbde9bc8a63 744 Gene3D G3DSA:1.25.40.10 283 509 9.1E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS32635 3cd3ace2020db47f32ba81e4726ca81a 304 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 304 164.626 T 29-03-2018 IPR011842 Coenzyme PQQ biosynthesis protein B GO:0006810|GO:0018189 THSYN_RS32635 3cd3ace2020db47f32ba81e4726ca81a 304 Pfam PF12706 Beta-lactamase superfamily domain 51 271 7.8E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS32635 3cd3ace2020db47f32ba81e4726ca81a 304 TIGRFAM TIGR02108 PQQ_syn_pqqB: coenzyme PQQ biosynthesis protein B 2 304 3.6E-128 T 29-03-2018 IPR011842 Coenzyme PQQ biosynthesis protein B GO:0006810|GO:0018189 THSYN_RS32635 3cd3ace2020db47f32ba81e4726ca81a 304 SUPERFAMILY SSF56281 1 304 4.06E-61 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS32635 3cd3ace2020db47f32ba81e4726ca81a 304 Gene3D G3DSA:3.60.15.10 1 304 7.2E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS09975 df1cba122ef07466a33f19510826d7e5 1099 Gene3D G3DSA:1.20.1170.10 290 701 5.9E-5 T 29-03-2018 THSYN_RS09975 df1cba122ef07466a33f19510826d7e5 1099 Pfam PF13809 Tubulin like 17 369 8.1E-41 T 29-03-2018 IPR025904 Tubulin-like THSYN_RS09975 df1cba122ef07466a33f19510826d7e5 1099 Gene3D G3DSA:3.40.50.1440 13 238 6.1E-11 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS27595 4db2e45b2b542bad782d55c55ca75365 107 SMART SM00028 18 51 0.017 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27595 4db2e45b2b542bad782d55c55ca75365 107 SMART SM00028 52 85 21.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS27595 4db2e45b2b542bad782d55c55ca75365 107 Pfam PF13432 Tetratricopeptide repeat 22 77 1.1E-8 T 29-03-2018 THSYN_RS27595 4db2e45b2b542bad782d55c55ca75365 107 SUPERFAMILY SSF48452 6 82 6.83E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27595 4db2e45b2b542bad782d55c55ca75365 107 Gene3D G3DSA:1.25.40.10 1 107 2.5E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS11845 029622ae3b8e05910731b4c2b625a30c 320 Gene3D G3DSA:2.160.20.10 15 253 1.8E-10 T 29-03-2018 IPR012334 Pectin lyase fold THSYN_RS11845 029622ae3b8e05910731b4c2b625a30c 320 SUPERFAMILY SSF51126 52 113 1.44E-7 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS11845 029622ae3b8e05910731b4c2b625a30c 320 SUPERFAMILY SSF51126 180 248 1.44E-7 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS29640 460d33d36e1c0ce3514dbf7661bb382e 408 Pfam PF04055 Radical SAM superfamily 5 90 1.7E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS29640 460d33d36e1c0ce3514dbf7661bb382e 408 SUPERFAMILY SSF102114 2 293 7.85E-20 T 29-03-2018 THSYN_RS29640 460d33d36e1c0ce3514dbf7661bb382e 408 Gene3D G3DSA:3.20.20.70 1 293 3.0E-15 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS04810 987726be3063d33ef2fc2875d22c1211 666 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 266 7.0E-66 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 THSYN_RS04810 987726be3063d33ef2fc2875d22c1211 666 Gene3D G3DSA:3.40.50.300 2 272 2.6E-52 T 29-03-2018 THSYN_RS04810 987726be3063d33ef2fc2875d22c1211 666 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 2 666 37.966 T 29-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 THSYN_RS04810 987726be3063d33ef2fc2875d22c1211 666 Gene3D G3DSA:3.40.50.300 275 379 3.7E-27 T 29-03-2018 THSYN_RS04810 987726be3063d33ef2fc2875d22c1211 666 Pfam PF13361 UvrD-like helicase C-terminal domain 272 612 1.4E-67 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THSYN_RS04810 987726be3063d33ef2fc2875d22c1211 666 SUPERFAMILY SSF52540 3 637 3.12E-162 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04810 987726be3063d33ef2fc2875d22c1211 666 Gene3D G3DSA:1.10.486.10 380 548 6.5E-38 T 29-03-2018 THSYN_RS17765 df76c5c0cca2de5429243d116bb2b460 132 Gene3D G3DSA:3.40.50.1010 1 50 4.2E-4 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS04605 6b52459c56c15f4515b4d9736641e036 398 Pfam PF00375 Sodium:dicarboxylate symporter family 9 387 1.2E-90 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 THSYN_RS04605 6b52459c56c15f4515b4d9736641e036 398 Gene3D G3DSA:1.10.3860.10 2 394 1.2E-98 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 THSYN_RS04605 6b52459c56c15f4515b4d9736641e036 398 PRINTS PR00173 Glutamate-aspartate symporter signature 280 306 6.3E-35 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 THSYN_RS04605 6b52459c56c15f4515b4d9736641e036 398 PRINTS PR00173 Glutamate-aspartate symporter signature 68 93 6.3E-35 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 THSYN_RS04605 6b52459c56c15f4515b4d9736641e036 398 PRINTS PR00173 Glutamate-aspartate symporter signature 40 60 6.3E-35 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 THSYN_RS04605 6b52459c56c15f4515b4d9736641e036 398 PRINTS PR00173 Glutamate-aspartate symporter signature 179 198 6.3E-35 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 THSYN_RS04605 6b52459c56c15f4515b4d9736641e036 398 PRINTS PR00173 Glutamate-aspartate symporter signature 342 362 6.3E-35 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 THSYN_RS04605 6b52459c56c15f4515b4d9736641e036 398 PRINTS PR00173 Glutamate-aspartate symporter signature 214 233 6.3E-35 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 THSYN_RS04605 6b52459c56c15f4515b4d9736641e036 398 PRINTS PR00173 Glutamate-aspartate symporter signature 315 334 6.3E-35 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 THSYN_RS04605 6b52459c56c15f4515b4d9736641e036 398 SUPERFAMILY SSF118215 9 387 2.09E-84 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 THSYN_RS28330 0733481c0c29b05faf29bb5fa401055a 183 Pfam PF01750 Hydrogenase maturation protease 24 147 3.8E-22 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS28330 0733481c0c29b05faf29bb5fa401055a 183 SUPERFAMILY SSF53163 4 155 1.57E-39 T 29-03-2018 IPR023430 Peptidase HybD-like domain THSYN_RS28330 0733481c0c29b05faf29bb5fa401055a 183 Gene3D G3DSA:3.40.50.1450 1 162 3.6E-43 T 29-03-2018 IPR023430 Peptidase HybD-like domain THSYN_RS28330 0733481c0c29b05faf29bb5fa401055a 183 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 6 150 1.7E-39 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS28330 0733481c0c29b05faf29bb5fa401055a 183 PRINTS PR00446 Hydrogen uptake protein signature 69 85 2.2E-12 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS28330 0733481c0c29b05faf29bb5fa401055a 183 PRINTS PR00446 Hydrogen uptake protein signature 58 68 2.2E-12 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS28330 0733481c0c29b05faf29bb5fa401055a 183 PRINTS PR00446 Hydrogen uptake protein signature 17 28 2.2E-12 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS28330 0733481c0c29b05faf29bb5fa401055a 183 PRINTS PR00446 Hydrogen uptake protein signature 37 54 2.2E-12 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS28330 0733481c0c29b05faf29bb5fa401055a 183 PRINTS PR00446 Hydrogen uptake protein signature 5 17 2.2E-12 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THSYN_RS23455 05497ee87e564a171f7bb296cfb18d97 374 Pfam PF01098 Cell cycle protein 34 373 5.0E-110 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 THSYN_RS23455 05497ee87e564a171f7bb296cfb18d97 374 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 28 374 1.6E-133 T 29-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 THSYN_RS23455 05497ee87e564a171f7bb296cfb18d97 374 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 331 355 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 THSYN_RS06715 4a6007580e6da15179cd755b4c6a9a45 219 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THSYN_RS06715 4a6007580e6da15179cd755b4c6a9a45 219 SUPERFAMILY SSF52540 1 186 1.17E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06715 4a6007580e6da15179cd755b4c6a9a45 219 Hamap MF_00235 Adenylate kinase [adk]. 1 217 50.058 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THSYN_RS06715 4a6007580e6da15179cd755b4c6a9a45 219 Gene3D G3DSA:3.40.50.300 1 219 4.9E-62 T 29-03-2018 THSYN_RS06715 4a6007580e6da15179cd755b4c6a9a45 219 TIGRFAM TIGR01351 adk: adenylate kinase 2 184 2.3E-71 T 29-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 THSYN_RS06715 4a6007580e6da15179cd755b4c6a9a45 219 PRINTS PR00094 Adenylate kinase signature 32 46 3.0E-34 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THSYN_RS06715 4a6007580e6da15179cd755b4c6a9a45 219 PRINTS PR00094 Adenylate kinase signature 4 17 3.0E-34 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THSYN_RS06715 4a6007580e6da15179cd755b4c6a9a45 219 PRINTS PR00094 Adenylate kinase signature 81 97 3.0E-34 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THSYN_RS06715 4a6007580e6da15179cd755b4c6a9a45 219 PRINTS PR00094 Adenylate kinase signature 173 187 3.0E-34 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THSYN_RS06715 4a6007580e6da15179cd755b4c6a9a45 219 PRINTS PR00094 Adenylate kinase signature 156 171 3.0E-34 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THSYN_RS06715 4a6007580e6da15179cd755b4c6a9a45 219 Pfam PF00406 Adenylate kinase 5 185 2.1E-55 T 29-03-2018 THSYN_RS06715 4a6007580e6da15179cd755b4c6a9a45 219 Pfam PF05191 Adenylate kinase, active site lid 123 158 3.3E-14 T 29-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 THSYN_RS02770 e258a50287035cfadcbf17e63b0ec2ff 456 Gene3D G3DSA:3.40.50.880 154 409 3.0E-16 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS02770 e258a50287035cfadcbf17e63b0ec2ff 456 Pfam PF09822 ABC-type uncharacterized transport system 46 266 9.6E-26 T 29-03-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 THSYN_RS02770 e258a50287035cfadcbf17e63b0ec2ff 456 SUPERFAMILY SSF52317 160 326 1.14E-6 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS02770 e258a50287035cfadcbf17e63b0ec2ff 456 SUPERFAMILY SSF52317 355 404 1.14E-6 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS22110 a5fd7ff3bed0457564046c00a4f2fc27 142 SUPERFAMILY SSF81301 19 119 5.18E-20 T 29-03-2018 THSYN_RS22110 a5fd7ff3bed0457564046c00a4f2fc27 142 Pfam PF01909 Nucleotidyltransferase domain 32 97 5.4E-8 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS22110 a5fd7ff3bed0457564046c00a4f2fc27 142 Gene3D G3DSA:3.30.460.10 13 120 3.2E-17 T 29-03-2018 THSYN_RS24660 8fbfb543c5b6e95badd7a3ccc96255cb 158 Gene3D G3DSA:2.40.280.10 14 133 2.2E-45 T 29-03-2018 IPR023620 Small protein B THSYN_RS24660 8fbfb543c5b6e95badd7a3ccc96255cb 158 Pfam PF01668 SmpB protein 14 156 4.0E-55 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 THSYN_RS24660 8fbfb543c5b6e95badd7a3ccc96255cb 158 ProSitePatterns PS01317 SsrA-binding protein. 32 44 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site THSYN_RS24660 8fbfb543c5b6e95badd7a3ccc96255cb 158 TIGRFAM TIGR00086 smpB: SsrA-binding protein 14 156 3.7E-49 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 THSYN_RS24660 8fbfb543c5b6e95badd7a3ccc96255cb 158 SUPERFAMILY SSF74982 8 138 1.12E-47 T 29-03-2018 IPR023620 Small protein B THSYN_RS24660 8fbfb543c5b6e95badd7a3ccc96255cb 158 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 14 138 3.0E-46 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 THSYN_RS24660 8fbfb543c5b6e95badd7a3ccc96255cb 158 Hamap MF_00023 SsrA-binding protein [smpB]. 1 158 68.386 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 THSYN_RS27855 bc65313bb87f172722aefbe01acac1d0 778 Gene3D G3DSA:3.40.710.10 262 617 1.6E-64 T 29-03-2018 THSYN_RS27855 bc65313bb87f172722aefbe01acac1d0 778 Pfam PF00912 Transglycosylase 74 225 1.5E-44 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 THSYN_RS27855 bc65313bb87f172722aefbe01acac1d0 778 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 53 771 2.7E-198 T 29-03-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 THSYN_RS27855 bc65313bb87f172722aefbe01acac1d0 778 Gene3D G3DSA:1.10.3810.10 57 261 1.2E-47 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 THSYN_RS27855 bc65313bb87f172722aefbe01acac1d0 778 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 692 769 4.1E-9 T 29-03-2018 IPR009647 Penicillin-binding, C-terminal THSYN_RS27855 bc65313bb87f172722aefbe01acac1d0 778 SUPERFAMILY SSF56601 263 639 2.05E-83 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS27855 bc65313bb87f172722aefbe01acac1d0 778 SUPERFAMILY SSF53955 55 226 1.27E-50 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS27855 bc65313bb87f172722aefbe01acac1d0 778 Pfam PF00905 Penicillin binding protein transpeptidase domain 308 471 1.2E-11 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THSYN_RS31455 028f2c4cae292b1b20908101e6ca2d66 484 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 16 437 8.1E-122 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit THSYN_RS31455 028f2c4cae292b1b20908101e6ca2d66 484 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 24 440 4.7E-97 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 THSYN_RS18435 0e5a6cd98c233c6a51c2955e305f9cc0 410 Hamap MF_02062 Sodium/glutamate symporter [gltS]. 8 410 23.711 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 THSYN_RS18435 0e5a6cd98c233c6a51c2955e305f9cc0 410 Pfam PF03616 Sodium/glutamate symporter 15 379 1.8E-110 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 THSYN_RS18435 0e5a6cd98c233c6a51c2955e305f9cc0 410 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 16 408 7.3E-126 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 THSYN_RS27150 57bc83ac6d99fb6d742683f706f7743c 344 Gene3D G3DSA:3.40.50.2300 194 333 9.4E-11 T 29-03-2018 THSYN_RS27150 57bc83ac6d99fb6d742683f706f7743c 344 Pfam PF13458 Periplasmic binding protein 13 325 2.0E-18 T 29-03-2018 IPR028081 Leucine-binding protein domain THSYN_RS27150 57bc83ac6d99fb6d742683f706f7743c 344 Gene3D G3DSA:3.40.50.2300 5 193 7.6E-16 T 29-03-2018 THSYN_RS27150 57bc83ac6d99fb6d742683f706f7743c 344 SUPERFAMILY SSF53822 10 331 2.35E-32 T 29-03-2018 IPR028082 Periplasmic binding protein-like I THSYN_RS13900 1626409ab9b6c03b035e44c07d8618af 87 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 9 53 2.7E-11 T 29-03-2018 IPR022453 Zinc finger, MqsA-type THSYN_RS28430 df062002ecf7b8a3d22077d355d14620 149 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 10 135 1.3E-53 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 THSYN_RS28430 df062002ecf7b8a3d22077d355d14620 149 Pfam PF01641 SelR domain 14 133 9.6E-54 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 THSYN_RS28430 df062002ecf7b8a3d22077d355d14620 149 SUPERFAMILY SSF51316 9 135 2.79E-58 T 29-03-2018 IPR011057 Mss4-like THSYN_RS28430 df062002ecf7b8a3d22077d355d14620 149 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 11 134 36.863 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 THSYN_RS28430 df062002ecf7b8a3d22077d355d14620 149 Gene3D G3DSA:2.170.150.20 1 146 2.1E-62 T 29-03-2018 THSYN_RS28830 fb5f86a2395f74de84775775e13d299a 141 Pfam PF04186 FxsA cytoplasmic membrane protein 6 110 6.3E-34 T 29-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 THSYN_RS30530 4aa695d64704df32a60839abc485ff62 580 Pfam PF03050 Transposase IS66 family 226 521 1.9E-43 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS09360 4aa695d64704df32a60839abc485ff62 580 Pfam PF03050 Transposase IS66 family 226 521 1.9E-43 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS29650 4aa695d64704df32a60839abc485ff62 580 Pfam PF03050 Transposase IS66 family 226 521 1.9E-43 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS31080 36c0ad562db46a84d79bab80b4a41006 323 SUPERFAMILY SSF161098 63 309 7.85E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS31080 36c0ad562db46a84d79bab80b4a41006 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 319 1.5E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS31080 36c0ad562db46a84d79bab80b4a41006 323 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 26 313 1.4E-86 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 THSYN_RS31080 36c0ad562db46a84d79bab80b4a41006 323 Gene3D G3DSA:1.10.3720.10 31 321 4.3E-33 T 29-03-2018 THSYN_RS18025 b193eceb8b34980d83b4fa3f36fd54d0 197 SMART SM00867 32 193 5.4E-42 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THSYN_RS18025 b193eceb8b34980d83b4fa3f36fd54d0 197 SUPERFAMILY SSF101874 35 194 1.96E-41 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THSYN_RS18025 b193eceb8b34980d83b4fa3f36fd54d0 197 Pfam PF04264 YceI-like domain 36 192 1.1E-32 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THSYN_RS18025 b193eceb8b34980d83b4fa3f36fd54d0 197 Gene3D G3DSA:2.40.128.110 35 196 1.8E-41 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THSYN_RS19410 b8998aa0e120b4f3f26f33be514c52d1 278 Pfam PF05107 CRISPR-associated protein Cas7 7 254 5.9E-89 T 29-03-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C THSYN_RS19410 b8998aa0e120b4f3f26f33be514c52d1 278 TIGRFAM TIGR02589 cas_Csd2: CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG 8 250 1.3E-84 T 29-03-2018 IPR013418 CRISPR-associated protein Csd2 THSYN_RS19410 b8998aa0e120b4f3f26f33be514c52d1 278 TIGRFAM TIGR01595 cas_CT1132: CRISPR-associated protein, CT1132 family 5 253 4.2E-64 T 29-03-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C THSYN_RS22305 cc84dc8cf831e1d9e3e5702702b3821d 268 Pfam PF01841 Transglutaminase-like superfamily 132 225 2.7E-19 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS22305 cc84dc8cf831e1d9e3e5702702b3821d 268 SUPERFAMILY SSF54001 49 256 1.16E-41 T 29-03-2018 THSYN_RS22305 cc84dc8cf831e1d9e3e5702702b3821d 268 Gene3D G3DSA:3.90.260.10 150 199 4.1E-8 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS22305 cc84dc8cf831e1d9e3e5702702b3821d 268 SMART SM00460 161 227 6.4E-14 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS14215 8d94f0f33d62322a632af0bb2e29f0e9 311 Gene3D G3DSA:3.40.50.2300 23 176 1.4E-18 T 29-03-2018 THSYN_RS14215 8d94f0f33d62322a632af0bb2e29f0e9 311 SUPERFAMILY SSF52172 26 161 4.54E-13 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS14215 8d94f0f33d62322a632af0bb2e29f0e9 311 Pfam PF00072 Response regulator receiver domain 37 129 1.3E-4 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS25855 0ad753f0bbbb4a7626b42d1eaa3c332d 286 Gene3D G3DSA:2.40.10.10 186 284 3.3E-35 T 29-03-2018 THSYN_RS25855 0ad753f0bbbb4a7626b42d1eaa3c332d 286 SUPERFAMILY SSF50494 54 277 1.55E-59 T 29-03-2018 IPR009003 Peptidase S1, PA clan THSYN_RS25855 0ad753f0bbbb4a7626b42d1eaa3c332d 286 PRINTS PR00834 HtrA/DegQ protease family signature 185 209 2.1E-45 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS25855 0ad753f0bbbb4a7626b42d1eaa3c332d 286 PRINTS PR00834 HtrA/DegQ protease family signature 124 136 2.1E-45 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS25855 0ad753f0bbbb4a7626b42d1eaa3c332d 286 PRINTS PR00834 HtrA/DegQ protease family signature 145 165 2.1E-45 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS25855 0ad753f0bbbb4a7626b42d1eaa3c332d 286 PRINTS PR00834 HtrA/DegQ protease family signature 220 237 2.1E-45 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS25855 0ad753f0bbbb4a7626b42d1eaa3c332d 286 PRINTS PR00834 HtrA/DegQ protease family signature 242 259 2.1E-45 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THSYN_RS25855 0ad753f0bbbb4a7626b42d1eaa3c332d 286 Pfam PF13365 Trypsin-like peptidase domain 114 249 1.7E-32 T 29-03-2018 THSYN_RS25855 0ad753f0bbbb4a7626b42d1eaa3c332d 286 Gene3D G3DSA:2.40.10.10 53 185 1.9E-31 T 29-03-2018 THSYN_RS13725 f1d35526a61271397f61b9f4f9677b24 99 Gene3D G3DSA:1.20.5.1230 2 99 8.3E-8 T 29-03-2018 THSYN_RS13725 f1d35526a61271397f61b9f4f9677b24 99 SUPERFAMILY SSF58113 4 94 1.31E-6 T 29-03-2018 THSYN_RS22410 a3f8f7607727d8f69c2ce0c9e7aec10c 172 Gene3D G3DSA:2.60.120.430 1 172 1.8E-18 T 29-03-2018 THSYN_RS22410 a3f8f7607727d8f69c2ce0c9e7aec10c 172 Pfam PF08547 Complex I intermediate-associated protein 30 (CIA30) 23 138 1.6E-18 T 29-03-2018 IPR013857 NADH:ubiquinone oxidoreductase intermediate-associated protein 30 Reactome: R-HSA-6799198 THSYN_RS22410 a3f8f7607727d8f69c2ce0c9e7aec10c 172 SUPERFAMILY SSF49785 24 172 1.11E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS27710 e0ac0b5422630f81a311f818968c2c18 149 Pfam PF01724 Domain of unknown function DUF29 8 144 1.7E-47 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS19545 9b6505e8afbea8458a2c7b71d47d7a58 272 Gene3D G3DSA:3.40.50.720 26 272 6.5E-48 T 29-03-2018 THSYN_RS19545 9b6505e8afbea8458a2c7b71d47d7a58 272 SUPERFAMILY SSF69572 25 268 1.44E-51 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THSYN_RS19545 9b6505e8afbea8458a2c7b71d47d7a58 272 Pfam PF00899 ThiF family 37 267 3.7E-34 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THSYN_RS11185 726de9bcd29c3c9694e12c80437f173d 109 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 51 104 3.6E-6 T 29-03-2018 THSYN_RS11185 726de9bcd29c3c9694e12c80437f173d 109 SUPERFAMILY SSF55166 15 105 7.32E-9 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS11185 726de9bcd29c3c9694e12c80437f173d 109 Gene3D G3DSA:3.30.1380.10 4 105 3.2E-5 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS22655 72bcac3f3e4446fb37b7426af30cbe03 165 SUPERFAMILY SSF48695 40 122 1.27E-12 T 29-03-2018 IPR011031 Multihaem cytochrome THSYN_RS22655 72bcac3f3e4446fb37b7426af30cbe03 165 Gene3D G3DSA:3.90.10.10 30 100 0.023 T 29-03-2018 THSYN_RS22655 72bcac3f3e4446fb37b7426af30cbe03 165 Gene3D G3DSA:1.10.468.10 101 146 3.4E-4 T 29-03-2018 THSYN_RS14765 17eb74d54a462564cf695926dfa047ab 191 Gene3D G3DSA:3.90.1570.10 6 187 6.4E-30 T 29-03-2018 THSYN_RS14765 17eb74d54a462564cf695926dfa047ab 191 SUPERFAMILY SSF52980 12 187 9.65E-32 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS14765 17eb74d54a462564cf695926dfa047ab 191 Pfam PF05685 Putative restriction endonuclease 12 162 3.5E-21 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS06830 46133c73d74315ce5073a00268eddfb9 668 SMART SM00882 22 259 1.2E-64 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 THSYN_RS06830 46133c73d74315ce5073a00268eddfb9 668 SMART SM00882 297 505 0.0011 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 THSYN_RS06830 46133c73d74315ce5073a00268eddfb9 668 SUPERFAMILY SSF100950 21 270 2.21E-90 T 29-03-2018 THSYN_RS06830 46133c73d74315ce5073a00268eddfb9 668 Pfam PF01144 Coenzyme A transferase 23 259 1.7E-35 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 THSYN_RS06830 46133c73d74315ce5073a00268eddfb9 668 Gene3D G3DSA:3.40.1080.10 291 538 2.3E-53 T 29-03-2018 THSYN_RS06830 46133c73d74315ce5073a00268eddfb9 668 Gene3D G3DSA:3.40.1080.10 9 284 1.2E-83 T 29-03-2018 THSYN_RS06830 46133c73d74315ce5073a00268eddfb9 668 SUPERFAMILY SSF100950 291 534 4.84E-77 T 29-03-2018 THSYN_RS08880 e1932aa89be6b6e57703739b12604b5e 71 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 47 1.4E-13 T 29-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type THSYN_RS08880 e1932aa89be6b6e57703739b12604b5e 71 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 1.2E-19 T 29-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type THSYN_RS07530 851ba7145eda04ae651ad8086cf08782 122 Gene3D G3DSA:3.40.50.1010 1 93 6.3E-7 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS07530 851ba7145eda04ae651ad8086cf08782 122 SUPERFAMILY SSF88723 1 65 8.69E-6 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS07530 851ba7145eda04ae651ad8086cf08782 122 Pfam PF13470 PIN domain 2 87 3.1E-10 T 29-03-2018 IPR002716 PIN domain THSYN_RS23800 8b71673d19244cd9bc43a36e3ebcb898 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 1.5E-55 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23800 8b71673d19244cd9bc43a36e3ebcb898 129 Pfam PF00411 Ribosomal protein S11 19 128 2.8E-52 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THSYN_RS23800 8b71673d19244cd9bc43a36e3ebcb898 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 32.856 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THSYN_RS23800 8b71673d19244cd9bc43a36e3ebcb898 129 Gene3D G3DSA:3.30.420.80 3 129 5.4E-46 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THSYN_RS23800 8b71673d19244cd9bc43a36e3ebcb898 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site THSYN_RS23800 8b71673d19244cd9bc43a36e3ebcb898 129 PIRSF PIRSF002131 1 129 3.7E-54 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THSYN_RS23800 8b71673d19244cd9bc43a36e3ebcb898 129 SUPERFAMILY SSF53137 14 129 3.79E-47 T 29-03-2018 THSYN_RS15445 d503bcec937c2d82b0ea7b5c0bc62564 679 Pfam PF17482 Phage tail sheath C-terminal domain 562 664 2.3E-8 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain THSYN_RS15445 d503bcec937c2d82b0ea7b5c0bc62564 679 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 441 561 6.2E-9 T 29-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain THSYN_RS14145 c3c25e01c3bf7d0afbc9418d22ddcfb5 254 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 58 80 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THSYN_RS14145 c3c25e01c3bf7d0afbc9418d22ddcfb5 254 Pfam PF01066 CDP-alcohol phosphatidyltransferase 17 80 5.2E-12 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THSYN_RS14145 c3c25e01c3bf7d0afbc9418d22ddcfb5 254 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 24 184 4.4E-35 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 THSYN_RS01610 1d08f17f8c3cbecda3107c4c2740a471 358 Gene3D G3DSA:3.20.20.70 1 358 1.8E-119 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS01610 1d08f17f8c3cbecda3107c4c2740a471 358 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 335 2.9E-91 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 THSYN_RS01610 1d08f17f8c3cbecda3107c4c2740a471 358 SUPERFAMILY SSF51395 2 357 2.98E-116 T 29-03-2018 THSYN_RS27285 6a8dac0d1ebfb20bfb5c6b9fc42c4466 249 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 32 240 9.3E-32 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 THSYN_RS27285 6a8dac0d1ebfb20bfb5c6b9fc42c4466 249 Gene3D G3DSA:3.40.630.40 29 245 2.5E-37 T 29-03-2018 THSYN_RS27285 6a8dac0d1ebfb20bfb5c6b9fc42c4466 249 SUPERFAMILY SSF53187 30 243 2.98E-29 T 29-03-2018 THSYN_RS27285 6a8dac0d1ebfb20bfb5c6b9fc42c4466 249 SMART SM00646 92 240 8.9E-8 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 THSYN_RS26885 89c38fd5aa2564cfac1803e4496840bb 271 SMART SM00563 77 188 1.3E-21 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THSYN_RS26885 89c38fd5aa2564cfac1803e4496840bb 271 Gene3D G3DSA:3.40.1130.10 42 249 6.9E-25 T 29-03-2018 THSYN_RS26885 89c38fd5aa2564cfac1803e4496840bb 271 SUPERFAMILY SSF69593 45 234 2.35E-25 T 29-03-2018 THSYN_RS26885 89c38fd5aa2564cfac1803e4496840bb 271 Pfam PF01553 Acyltransferase 74 184 6.1E-16 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THSYN_RS01385 667ef5eb37bd6132fd909d69324134fe 285 Pfam PF04809 HupH hydrogenase expression protein, C-terminal conserved region 167 283 9.1E-44 T 29-03-2018 IPR006894 HupH hydrogenase expression protein, C-terminal THSYN_RS01385 667ef5eb37bd6132fd909d69324134fe 285 Pfam PF04809 HupH hydrogenase expression protein, C-terminal conserved region 54 148 3.1E-15 T 29-03-2018 IPR006894 HupH hydrogenase expression protein, C-terminal THSYN_RS01385 667ef5eb37bd6132fd909d69324134fe 285 ProDom PD005668 HYDROGENASE HUPH HYDROGENASE-1 EXPRESSION/FORMATION OPERON PROTEIN C-TERMINAL EXPRESSION HYAF HOXQ 76 145 2.0E-7 T 29-03-2018 IPR006894 HupH hydrogenase expression protein, C-terminal THSYN_RS01385 667ef5eb37bd6132fd909d69324134fe 285 ProDom PD005668 HYDROGENASE HUPH HYDROGENASE-1 EXPRESSION/FORMATION OPERON PROTEIN C-TERMINAL EXPRESSION HYAF HOXQ 167 273 1.0E-32 T 29-03-2018 IPR006894 HupH hydrogenase expression protein, C-terminal THSYN_RS26910 9c1bc4ee1b9ab18185f93e741fc85a14 129 Pfam PF05168 HEPN domain 6 117 1.9E-17 T 29-03-2018 IPR007842 HEPN domain THSYN_RS26910 9c1bc4ee1b9ab18185f93e741fc85a14 129 Gene3D G3DSA:1.20.120.330 1 126 1.4E-24 T 29-03-2018 THSYN_RS19160 719eb486410dfec610c5b72dc6b15695 222 Pfam PF08856 Protein of unknown function (DUF1826) 25 219 4.2E-48 T 29-03-2018 IPR014955 Protein of unknown function DUF1826 THSYN_RS07095 e1adce358a4dc92069b209447ae5d22b 640 Pfam PF08298 PrkA AAA domain 19 376 3.8E-171 T 29-03-2018 IPR013153 PrkA AAA domain THSYN_RS07095 e1adce358a4dc92069b209447ae5d22b 640 SMART SM00763 19 376 2.1E-210 T 29-03-2018 IPR013153 PrkA AAA domain THSYN_RS07095 e1adce358a4dc92069b209447ae5d22b 640 SUPERFAMILY SSF52540 75 161 6.92E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07095 e1adce358a4dc92069b209447ae5d22b 640 SUPERFAMILY SSF52540 249 364 6.92E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07095 e1adce358a4dc92069b209447ae5d22b 640 PIRSF PIRSF000549 1 640 2.7E-281 T 29-03-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 THSYN_RS07095 e1adce358a4dc92069b209447ae5d22b 640 Pfam PF06798 PrkA serine protein kinase C-terminal domain 379 632 4.2E-70 T 29-03-2018 IPR010650 PrkA C-terminal domain THSYN_RS07095 e1adce358a4dc92069b209447ae5d22b 640 Gene3D G3DSA:3.40.50.300 62 381 6.2E-12 T 29-03-2018 THSYN_RS32110 4051f97b91b9d013c809a67819457123 760 Gene3D G3DSA:2.60.120.620 45 215 5.4E-20 T 29-03-2018 THSYN_RS32110 4051f97b91b9d013c809a67819457123 760 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 120 207 8.4E-10 T 29-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 THSYN_RS11035 19d49077fb370ff0ba2cb6718e194bfa 694 PRINTS PR00723 Subtilisin serine protease family (S8) signature 134 147 7.4E-13 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS11035 19d49077fb370ff0ba2cb6718e194bfa 694 PRINTS PR00723 Subtilisin serine protease family (S8) signature 96 115 7.4E-13 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS11035 19d49077fb370ff0ba2cb6718e194bfa 694 PRINTS PR00723 Subtilisin serine protease family (S8) signature 290 306 7.4E-13 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS11035 19d49077fb370ff0ba2cb6718e194bfa 694 SUPERFAMILY SSF50998 441 563 9.81E-5 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS11035 19d49077fb370ff0ba2cb6718e194bfa 694 Pfam PF00082 Subtilase family 100 341 2.0E-31 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS11035 19d49077fb370ff0ba2cb6718e194bfa 694 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 101 112 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site THSYN_RS11035 19d49077fb370ff0ba2cb6718e194bfa 694 Gene3D G3DSA:3.40.50.200 40 354 4.1E-72 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS11035 19d49077fb370ff0ba2cb6718e194bfa 694 SUPERFAMILY SSF52743 78 350 2.09E-70 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS23880 28152050059282941a2c4c40f81a711d 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 9.4E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23880 28152050059282941a2c4c40f81a711d 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 9.4E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23880 28152050059282941a2c4c40f81a711d 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 9.4E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23880 28152050059282941a2c4c40f81a711d 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 9.4E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23880 28152050059282941a2c4c40f81a711d 137 SUPERFAMILY SSF54686 1 132 5.49E-54 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 THSYN_RS23880 28152050059282941a2c4c40f81a711d 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.1E-60 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23880 28152050059282941a2c4c40f81a711d 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.258 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23880 28152050059282941a2c4c40f81a711d 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23880 28152050059282941a2c4c40f81a711d 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23880 28152050059282941a2c4c40f81a711d 137 Gene3D G3DSA:3.90.1170.10 1 135 1.4E-47 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 THSYN_RS23880 28152050059282941a2c4c40f81a711d 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 131 9.4E-49 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 THSYN_RS31945 c24a15bc70e4002c392f1357ae473970 474 PIRSF PIRSF029063 255 474 5.8E-74 T 29-03-2018 IPR011225 Type IV secretory pathway, VirJ component THSYN_RS31945 c24a15bc70e4002c392f1357ae473970 474 PIRSF PIRSF029063 5 195 8.4E-11 T 29-03-2018 IPR011225 Type IV secretory pathway, VirJ component THSYN_RS31945 c24a15bc70e4002c392f1357ae473970 474 Gene3D G3DSA:3.40.50.1820 29 265 3.7E-8 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS31945 c24a15bc70e4002c392f1357ae473970 474 SUPERFAMILY SSF53474 274 470 1.14E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS31945 c24a15bc70e4002c392f1357ae473970 474 Gene3D G3DSA:3.40.50.1820 266 441 7.0E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS31945 c24a15bc70e4002c392f1357ae473970 474 SUPERFAMILY SSF53474 27 208 1.57E-7 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS31945 c24a15bc70e4002c392f1357ae473970 474 Pfam PF06057 Bacterial virulence protein (VirJ) 286 472 8.0E-64 T 29-03-2018 IPR010333 Bacterial virulence THSYN_RS32985 fa72abed76a2cfb4818177894101596f 268 PIRSF PIRSF006648 4 258 2.6E-34 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THSYN_RS32985 fa72abed76a2cfb4818177894101596f 268 Pfam PF01061 ABC-2 type transporter 13 227 1.2E-33 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 THSYN_RS32985 fa72abed76a2cfb4818177894101596f 268 TIGRFAM TIGR03861 phenyl_ABC_PedC: alcohol ABC transporter, permease protein 9 258 4.5E-119 T 29-03-2018 IPR022403 Alcohol ABC transporter, permease protein THSYN_RS32985 fa72abed76a2cfb4818177894101596f 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 145 169 8.3E-12 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THSYN_RS32985 fa72abed76a2cfb4818177894101596f 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 182 201 8.3E-12 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THSYN_RS32985 fa72abed76a2cfb4818177894101596f 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 28 49 8.3E-12 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THSYN_RS15255 199bac64a4196a3674ed4c8f136dd315 58 Pfam PF05532 CsbD-like 4 55 4.1E-12 T 29-03-2018 IPR008462 CsbD-like domain THSYN_RS15255 199bac64a4196a3674ed4c8f136dd315 58 Gene3D G3DSA:1.10.1470.10 1 58 2.6E-13 T 29-03-2018 IPR008462 CsbD-like domain THSYN_RS15255 199bac64a4196a3674ed4c8f136dd315 58 SUPERFAMILY SSF69047 1 55 3.53E-11 T 29-03-2018 IPR008462 CsbD-like domain THSYN_RS19905 c8b985b53e74aa573c73782d738a5439 95 SUPERFAMILY SSF47413 36 80 1.97E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS19905 c8b985b53e74aa573c73782d738a5439 95 Gene3D G3DSA:1.10.260.40 28 91 8.8E-9 T 29-03-2018 THSYN_RS31305 d954e3fe19be3788d5c10df3359706c4 615 Gene3D G3DSA:3.50.50.60 33 293 7.1E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31305 d954e3fe19be3788d5c10df3359706c4 615 SUPERFAMILY SSF50022 316 391 7.07E-23 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THSYN_RS31305 d954e3fe19be3788d5c10df3359706c4 615 Pfam PF01593 Flavin containing amine oxidoreductase 394 592 1.5E-8 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THSYN_RS31305 d954e3fe19be3788d5c10df3359706c4 615 Pfam PF13450 NAD(P)-binding Rossmann-like domain 38 106 4.3E-13 T 29-03-2018 THSYN_RS31305 d954e3fe19be3788d5c10df3359706c4 615 PRINTS PR00162 Rieske 2Fe-2S subunit signature 328 339 2.6E-5 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THSYN_RS31305 d954e3fe19be3788d5c10df3359706c4 615 PRINTS PR00162 Rieske 2Fe-2S subunit signature 349 361 2.6E-5 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THSYN_RS31305 d954e3fe19be3788d5c10df3359706c4 615 PRINTS PR00162 Rieske 2Fe-2S subunit signature 361 373 2.6E-5 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THSYN_RS31305 d954e3fe19be3788d5c10df3359706c4 615 Gene3D G3DSA:2.102.10.10 294 404 1.6E-20 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THSYN_RS31305 d954e3fe19be3788d5c10df3359706c4 615 SUPERFAMILY SSF51905 551 593 1.06E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31305 d954e3fe19be3788d5c10df3359706c4 615 SUPERFAMILY SSF51905 394 450 1.06E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31305 d954e3fe19be3788d5c10df3359706c4 615 SUPERFAMILY SSF51905 34 284 1.06E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31305 d954e3fe19be3788d5c10df3359706c4 615 Pfam PF00355 Rieske [2Fe-2S] domain 311 374 2.2E-12 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THSYN_RS18530 ad0d993a2e790e8433243662f041465a 701 SUPERFAMILY SSF143011 1 81 4.32E-5 T 29-03-2018 IPR035095 Toxin RelE-like domain THSYN_RS18530 ad0d993a2e790e8433243662f041465a 701 Pfam PF13245 AAA domain 246 477 1.3E-10 T 29-03-2018 THSYN_RS18530 ad0d993a2e790e8433243662f041465a 701 Pfam PF13361 UvrD-like helicase C-terminal domain 610 677 7.3E-12 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THSYN_RS18530 ad0d993a2e790e8433243662f041465a 701 Gene3D G3DSA:3.40.50.300 501 701 5.6E-36 T 29-03-2018 THSYN_RS18530 ad0d993a2e790e8433243662f041465a 701 Gene3D G3DSA:3.30.2310.20 1 86 4.3E-8 T 29-03-2018 THSYN_RS18530 ad0d993a2e790e8433243662f041465a 701 Gene3D G3DSA:3.40.50.300 229 500 5.8E-29 T 29-03-2018 THSYN_RS18530 ad0d993a2e790e8433243662f041465a 701 SUPERFAMILY SSF52540 223 687 1.74E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12540 69aee8f714b7c74c76e7c94ad5fc82bf 265 SUPERFAMILY SSF56436 32 259 6.97E-70 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS12540 69aee8f714b7c74c76e7c94ad5fc82bf 265 Gene3D G3DSA:3.90.1580.10 19 263 4.6E-66 T 29-03-2018 THSYN_RS12540 69aee8f714b7c74c76e7c94ad5fc82bf 265 Pfam PF03781 Sulfatase-modifying factor enzyme 1 32 257 7.3E-55 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS00090 a9a56034045013875129e98c0fac1ffc 89 Gene3D G3DSA:1.10.1220.10 1 80 1.3E-5 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS00090 a9a56034045013875129e98c0fac1ffc 89 SUPERFAMILY SSF47598 3 54 1.33E-7 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS13975 c50eebd36d16b2e6f8fc2d729a6de6ba 161 Gene3D G3DSA:1.10.287.950 12 149 7.1E-7 T 29-03-2018 THSYN_RS13975 c50eebd36d16b2e6f8fc2d729a6de6ba 161 SUPERFAMILY SSF58104 62 155 5.49E-5 T 29-03-2018 THSYN_RS22280 0596d967a92b21781735c93567eaf299 285 Gene3D G3DSA:1.10.3680.10 31 189 7.6E-21 T 29-03-2018 IPR029024 TerB-like THSYN_RS22280 0596d967a92b21781735c93567eaf299 285 SMART SM00271 214 279 1.7E-11 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS22280 0596d967a92b21781735c93567eaf299 285 PRINTS PR00625 DnaJ domain signature 217 235 1.5E-9 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS22280 0596d967a92b21781735c93567eaf299 285 PRINTS PR00625 DnaJ domain signature 259 279 1.5E-9 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS22280 0596d967a92b21781735c93567eaf299 285 PRINTS PR00625 DnaJ domain signature 235 250 1.5E-9 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS22280 0596d967a92b21781735c93567eaf299 285 Gene3D G3DSA:1.10.287.110 207 276 1.8E-14 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS22280 0596d967a92b21781735c93567eaf299 285 Pfam PF05099 Tellurite resistance protein TerB 44 141 8.9E-7 T 29-03-2018 IPR007791 Co-chaperone DjlA, N-terminal THSYN_RS22280 0596d967a92b21781735c93567eaf299 285 SUPERFAMILY SSF46565 136 275 9.73E-18 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS22280 0596d967a92b21781735c93567eaf299 285 SUPERFAMILY SSF158682 55 177 5.23E-11 T 29-03-2018 THSYN_RS22280 0596d967a92b21781735c93567eaf299 285 Pfam PF00226 DnaJ domain 216 275 1.8E-11 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS14945 d09f9a268a5e6381a00ccbbe986f9496 672 Gene3D G3DSA:3.90.1580.10 113 317 2.0E-22 T 29-03-2018 THSYN_RS14945 d09f9a268a5e6381a00ccbbe986f9496 672 SUPERFAMILY SSF56436 115 322 3.3E-26 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS14945 d09f9a268a5e6381a00ccbbe986f9496 672 Pfam PF03781 Sulfatase-modifying factor enzyme 1 115 321 1.3E-19 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS14945 d09f9a268a5e6381a00ccbbe986f9496 672 Gene3D G3DSA:1.20.5.320 461 576 0.033 T 29-03-2018 THSYN_RS30740 f52255372aa3358cdb0836e38af92c2d 109 SUPERFAMILY SSF55729 1 98 1.56E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS30740 f52255372aa3358cdb0836e38af92c2d 109 Gene3D G3DSA:3.40.630.30 1 103 2.5E-12 T 29-03-2018 THSYN_RS07940 512b805b4d17c29b3c7c68b458d467a2 464 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 23 390 6.8E-29 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS07940 512b805b4d17c29b3c7c68b458d467a2 464 SUPERFAMILY SSF52540 1 72 1.71E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07940 512b805b4d17c29b3c7c68b458d467a2 464 SUPERFAMILY SSF52540 252 394 1.71E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07940 512b805b4d17c29b3c7c68b458d467a2 464 Gene3D G3DSA:3.40.50.300 1 404 3.2E-24 T 29-03-2018 THSYN_RS07025 399f11fe433db4b6a6e150782f5783bb 388 SMART SM00342 289 375 2.2E-15 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THSYN_RS07025 399f11fe433db4b6a6e150782f5783bb 388 Pfam PF12833 Helix-turn-helix domain 295 377 1.3E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THSYN_RS07025 399f11fe433db4b6a6e150782f5783bb 388 SUPERFAMILY SSF46689 276 323 9.51E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS07025 399f11fe433db4b6a6e150782f5783bb 388 Gene3D G3DSA:1.10.10.60 328 380 5.4E-5 T 29-03-2018 THSYN_RS07025 399f11fe433db4b6a6e150782f5783bb 388 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 326 371 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THSYN_RS07025 399f11fe433db4b6a6e150782f5783bb 388 Gene3D G3DSA:1.10.10.60 183 327 2.0E-10 T 29-03-2018 THSYN_RS12970 564656b60a6f4faa14155c16758c77e1 91 Gene3D G3DSA:1.10.1220.10 5 54 4.7E-8 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS12970 564656b60a6f4faa14155c16758c77e1 91 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 43 3.5E-6 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 THSYN_RS23110 7af88aa7574038fdf908b7db832a1eea 337 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 248 337 2.2E-30 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THSYN_RS23110 7af88aa7574038fdf908b7db832a1eea 337 Gene3D G3DSA:3.40.47.10 1 173 8.1E-22 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS23110 7af88aa7574038fdf908b7db832a1eea 337 SUPERFAMILY SSF53901 6 337 1.51E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS23110 7af88aa7574038fdf908b7db832a1eea 337 Gene3D G3DSA:3.40.47.10 174 337 3.5E-36 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS23110 7af88aa7574038fdf908b7db832a1eea 337 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 108 187 1.0E-19 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THSYN_RS00630 87c17b579f4c2228340a3b36467cbcf6 139 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 131 11.962 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS00630 87c17b579f4c2228340a3b36467cbcf6 139 SUPERFAMILY SSF88723 3 134 2.16E-37 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS00630 87c17b579f4c2228340a3b36467cbcf6 139 Pfam PF01850 PIN domain 6 126 1.9E-21 T 29-03-2018 IPR002716 PIN domain THSYN_RS00630 87c17b579f4c2228340a3b36467cbcf6 139 SMART SM00670 4 123 1.8E-6 T 29-03-2018 IPR002716 PIN domain THSYN_RS00630 87c17b579f4c2228340a3b36467cbcf6 139 Gene3D G3DSA:3.40.50.1010 2 138 1.5E-29 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS07535 38815a49d3a4e1bd1b5f7d000baecb54 810 SMART SM00487 61 269 3.2E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THSYN_RS07535 38815a49d3a4e1bd1b5f7d000baecb54 810 Gene3D G3DSA:3.40.50.300 9 262 2.7E-35 T 29-03-2018 THSYN_RS07535 38815a49d3a4e1bd1b5f7d000baecb54 810 SUPERFAMILY SSF52540 270 410 5.8E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07535 38815a49d3a4e1bd1b5f7d000baecb54 810 SUPERFAMILY SSF52540 75 241 5.8E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS07535 38815a49d3a4e1bd1b5f7d000baecb54 810 Pfam PF00271 Helicase conserved C-terminal domain 298 401 4.0E-12 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS07535 38815a49d3a4e1bd1b5f7d000baecb54 810 Gene3D G3DSA:3.40.50.300 282 444 2.4E-22 T 29-03-2018 THSYN_RS07535 38815a49d3a4e1bd1b5f7d000baecb54 810 Pfam PF09369 Domain of unknown function (DUF1998) 667 771 9.7E-12 T 29-03-2018 IPR018973 DEAD/DEAH-box helicase, putative THSYN_RS07535 38815a49d3a4e1bd1b5f7d000baecb54 810 Pfam PF00270 DEAD/DEAH box helicase 67 239 3.6E-25 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THSYN_RS07535 38815a49d3a4e1bd1b5f7d000baecb54 810 SMART SM00490 315 403 1.1E-13 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS22505 e3b4c608efc56dbad3cc11454d438b11 334 SUPERFAMILY SSF52096 222 282 4.04E-40 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS22505 e3b4c608efc56dbad3cc11454d438b11 334 SUPERFAMILY SSF52096 67 193 4.04E-40 T 29-03-2018 IPR029045 ClpP/crotonase-like domain THSYN_RS22505 e3b4c608efc56dbad3cc11454d438b11 334 Gene3D G3DSA:3.90.226.10 58 308 5.3E-34 T 29-03-2018 THSYN_RS22505 e3b4c608efc56dbad3cc11454d438b11 334 Pfam PF01343 Peptidase family S49 148 289 5.1E-33 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 THSYN_RS07790 b620a42466e78f50bf753753e75873a6 237 PIRSF PIRSF001488 3 209 1.5E-40 T 29-03-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL THSYN_RS07790 b620a42466e78f50bf753753e75873a6 237 Pfam PF01323 DSBA-like thioredoxin domain 94 183 2.1E-15 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 THSYN_RS07790 b620a42466e78f50bf753753e75873a6 237 SUPERFAMILY SSF52833 39 204 1.11E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS07790 b620a42466e78f50bf753753e75873a6 237 Gene3D G3DSA:3.40.30.10 25 205 2.7E-40 T 29-03-2018 THSYN_RS02580 7c010959bd8636d9e3523ffa08b0ba7d 283 Pfam PF04340 Protein of unknown function, DUF484 34 243 1.7E-37 T 29-03-2018 IPR007435 Protein of unknown function DUF484 THSYN_RS02580 7c010959bd8636d9e3523ffa08b0ba7d 283 Gene3D G3DSA:3.30.450.40 68 244 3.0E-11 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS10975 f9d28d152930bb8145713176a3f07203 205 SUPERFAMILY SSF110997 130 198 5.49E-13 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 THSYN_RS10975 f9d28d152930bb8145713176a3f07203 205 Gene3D G3DSA:3.30.70.1070 130 202 3.4E-13 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 THSYN_RS10975 f9d28d152930bb8145713176a3f07203 205 Pfam PF05036 Sporulation related domain 130 201 9.1E-14 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 THSYN_RS32850 c2a085865e835aca7b13b70a3b122104 366 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 42 343 5.2E-107 T 29-03-2018 IPR010732 Type VI secretion, TssG-like THSYN_RS32850 c2a085865e835aca7b13b70a3b122104 366 Pfam PF06996 Type VI secretion, TssG 41 342 3.8E-108 T 29-03-2018 IPR010732 Type VI secretion, TssG-like THSYN_RS19465 d575f09e187a60102b80bd11b36f0742 270 SUPERFAMILY SSF48452 82 180 8.85E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS19465 d575f09e187a60102b80bd11b36f0742 270 Gene3D G3DSA:1.25.40.10 32 242 4.6E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS25295 4f7a5c6cd2ef9a196314c68e347d13db 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 14 60 9.7E-12 T 29-03-2018 THSYN_RS25295 4f7a5c6cd2ef9a196314c68e347d13db 141 TIGRFAM TIGR04176 MarR_EPS: EPS-associated transcriptional regulator, MarR family 13 115 5.9E-45 T 29-03-2018 IPR026433 EPS-associated transcriptional regulator, MarR family THSYN_RS25295 4f7a5c6cd2ef9a196314c68e347d13db 141 Gene3D G3DSA:1.10.10.10 5 121 1.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25295 4f7a5c6cd2ef9a196314c68e347d13db 141 SUPERFAMILY SSF46785 5 117 4.4E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS32335 6674464f83773a6dc773cde6101f0cc9 123 SUPERFAMILY SSF55307 7 85 7.1E-5 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 THSYN_RS20570 3d563fbdbef59207c0dac9319a5a667d 252 Pfam PF13672 Protein phosphatase 2C 11 228 1.7E-52 T 29-03-2018 THSYN_RS20570 3d563fbdbef59207c0dac9319a5a667d 252 Gene3D G3DSA:3.60.40.10 2 248 2.9E-15 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS20570 3d563fbdbef59207c0dac9319a5a667d 252 SUPERFAMILY SSF81606 10 246 2.09E-15 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS01605 b33943d0bdf1560b1622a3fd897672b9 301 Gene3D G3DSA:1.10.10.10 227 281 6.1E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS01605 b33943d0bdf1560b1622a3fd897672b9 301 SUPERFAMILY SSF52833 7 219 3.75E-29 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS01605 b33943d0bdf1560b1622a3fd897672b9 301 Pfam PF13743 Thioredoxin 11 189 6.9E-30 T 29-03-2018 THSYN_RS01605 b33943d0bdf1560b1622a3fd897672b9 301 Gene3D G3DSA:3.40.30.10 5 225 4.2E-31 T 29-03-2018 THSYN_RS06975 3ae244edabbd42f1432acff7e6cf1cb4 355 TIGRFAM TIGR01834 PHA_synth_III_E: poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit 2 307 6.2E-91 T 29-03-2018 IPR010123 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit THSYN_RS06975 3ae244edabbd42f1432acff7e6cf1cb4 355 Pfam PF09712 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) 1 297 3.7E-104 T 29-03-2018 IPR010123 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit THSYN_RS07945 3efdd6246b3e6530647aae5357b27201 221 Pfam PF14103 Domain of unknown function (DUF4276) 10 210 7.5E-11 T 29-03-2018 IPR025455 Protein of unknown function DUF4276 THSYN_RS05065 df391d1b02f7b4af9f1e4a056b370d83 797 Gene3D G3DSA:3.40.50.150 192 620 1.0E-37 T 29-03-2018 THSYN_RS05065 df391d1b02f7b4af9f1e4a056b370d83 797 SUPERFAMILY SSF53335 78 508 5.55E-101 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS05065 df391d1b02f7b4af9f1e4a056b370d83 797 SUPERFAMILY SSF53335 7 47 5.55E-101 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS05065 df391d1b02f7b4af9f1e4a056b370d83 797 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 306 312 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS05065 df391d1b02f7b4af9f1e4a056b370d83 797 Pfam PF12161 HsdM N-terminal domain 9 145 3.0E-17 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS05065 df391d1b02f7b4af9f1e4a056b370d83 797 Pfam PF02384 N-6 DNA Methylase 171 481 5.5E-49 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS05065 df391d1b02f7b4af9f1e4a056b370d83 797 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 303 315 7.6E-11 T 29-03-2018 THSYN_RS05065 df391d1b02f7b4af9f1e4a056b370d83 797 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 194 210 7.6E-11 T 29-03-2018 THSYN_RS05065 df391d1b02f7b4af9f1e4a056b370d83 797 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 225 239 7.6E-11 T 29-03-2018 THSYN_RS05430 d6a7a5d631933c2c9272475b6ce71aad 865 Gene3D G3DSA:3.30.1380.10 703 848 7.4E-21 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS05430 d6a7a5d631933c2c9272475b6ce71aad 865 SUPERFAMILY SSF55166 714 841 4.0E-11 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS05430 d6a7a5d631933c2c9272475b6ce71aad 865 TIGRFAM TIGR04096 dnd_rel_methyl: DNA phosphorothioation-associated putative methyltransferase 188 688 2.1E-143 T 29-03-2018 IPR024019 Conserved hypothetical protein CHP04096 THSYN_RS27955 66c3207662097e97a2869bdea09955e2 328 SUPERFAMILY SSF141523 111 248 3.14E-34 T 29-03-2018 THSYN_RS27955 66c3207662097e97a2869bdea09955e2 328 Gene3D G3DSA:2.40.440.10 106 250 1.1E-34 T 29-03-2018 THSYN_RS27955 66c3207662097e97a2869bdea09955e2 328 Pfam PF03734 L,D-transpeptidase catalytic domain 115 248 5.2E-22 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 THSYN_RS06065 c1488594f8195b25c20e5b8a67e56b4c 381 Pfam PF13439 Glycosyltransferase Family 4 16 176 7.8E-13 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS06065 c1488594f8195b25c20e5b8a67e56b4c 381 SUPERFAMILY SSF53756 5 373 4.71E-56 T 29-03-2018 THSYN_RS06065 c1488594f8195b25c20e5b8a67e56b4c 381 Pfam PF00534 Glycosyl transferases group 1 200 337 1.4E-24 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS06065 c1488594f8195b25c20e5b8a67e56b4c 381 Gene3D G3DSA:3.40.50.2000 1 189 3.2E-8 T 29-03-2018 THSYN_RS06065 c1488594f8195b25c20e5b8a67e56b4c 381 Gene3D G3DSA:3.40.50.2000 191 358 1.1E-33 T 29-03-2018 THSYN_RS18655 69db96481e9c0db1c316ae9f5fe6b4f2 388 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 55 264 6.4E-32 T 29-03-2018 IPR000477 Reverse transcriptase domain THSYN_RS18655 69db96481e9c0db1c316ae9f5fe6b4f2 388 SUPERFAMILY SSF56672 56 298 2.45E-36 T 29-03-2018 THSYN_RS18655 69db96481e9c0db1c316ae9f5fe6b4f2 388 Gene3D G3DSA:3.30.70.270 72 264 1.9E-28 T 29-03-2018 THSYN_RS09350 5ca5ba2823f80fa585b418d159e14286 354 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 56 292 4.4E-68 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA THSYN_RS09350 5ca5ba2823f80fa585b418d159e14286 354 SUPERFAMILY SSF56300 54 307 1.06E-37 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS09350 5ca5ba2823f80fa585b418d159e14286 354 SMART SM00854 56 293 1.7E-85 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA THSYN_RS09350 5ca5ba2823f80fa585b418d159e14286 354 Gene3D G3DSA:3.60.21.10 41 324 1.8E-51 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS21815 172ed9f091edaf021aae09164d28acb5 207 SUPERFAMILY SSF101307 57 199 1.57E-40 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 THSYN_RS21815 172ed9f091edaf021aae09164d28acb5 207 PIRSF PIRSF006162 51 206 8.5E-46 T 29-03-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 THSYN_RS21815 172ed9f091edaf021aae09164d28acb5 207 Pfam PF04608 Phosphatidylglycerophosphatase A 62 198 7.8E-47 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 THSYN_RS21815 172ed9f091edaf021aae09164d28acb5 207 Gene3D G3DSA:1.10.3760.10 97 202 3.2E-35 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 THSYN_RS03260 6c1603605004b9d6ba6d245910c1f18f 207 SUPERFAMILY SSF53335 22 196 1.89E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS03260 6c1603605004b9d6ba6d245910c1f18f 207 Pfam PF06080 Protein of unknown function (DUF938) 9 201 3.0E-62 T 29-03-2018 IPR010342 Protein of unknown function DUF938 THSYN_RS03260 6c1603605004b9d6ba6d245910c1f18f 207 Gene3D G3DSA:3.40.50.150 5 206 3.6E-23 T 29-03-2018 THSYN_RS28205 1a5c9087e94980be4995434d229641a7 279 Gene3D G3DSA:3.30.572.10 1 279 2.7E-116 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THSYN_RS28205 1a5c9087e94980be4995434d229641a7 279 PRINTS PR00108 Thymidylate synthase family signature 210 227 2.2E-40 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THSYN_RS28205 1a5c9087e94980be4995434d229641a7 279 PRINTS PR00108 Thymidylate synthase family signature 42 63 2.2E-40 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THSYN_RS28205 1a5c9087e94980be4995434d229641a7 279 PRINTS PR00108 Thymidylate synthase family signature 154 169 2.2E-40 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THSYN_RS28205 1a5c9087e94980be4995434d229641a7 279 PRINTS PR00108 Thymidylate synthase family signature 172 198 2.2E-40 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THSYN_RS28205 1a5c9087e94980be4995434d229641a7 279 Pfam PF00303 Thymidylate synthase 3 279 7.8E-109 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THSYN_RS28205 1a5c9087e94980be4995434d229641a7 279 Hamap MF_00008 Thymidylate synthase [thyA]. 1 279 37.772 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THSYN_RS28205 1a5c9087e94980be4995434d229641a7 279 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 86 279 5.8E-82 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THSYN_RS28205 1a5c9087e94980be4995434d229641a7 279 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 84 3.1E-33 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THSYN_RS28205 1a5c9087e94980be4995434d229641a7 279 SUPERFAMILY SSF55831 1 279 4.97E-113 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THSYN_RS30545 f1bc6fbab4c43e8599600dcfcf65e75e 149 Pfam PF00436 Single-strand binding protein family 7 90 5.1E-8 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 THSYN_RS30545 f1bc6fbab4c43e8599600dcfcf65e75e 149 SUPERFAMILY SSF50249 6 140 1.47E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS30545 f1bc6fbab4c43e8599600dcfcf65e75e 149 Gene3D G3DSA:2.40.50.140 4 120 2.3E-15 T 29-03-2018 THSYN_RS30545 f1bc6fbab4c43e8599600dcfcf65e75e 149 PIRSF PIRSF002070 1 145 2.4E-14 T 29-03-2018 THSYN_RS17190 eb67954172bc000d0febec2a57baaa48 152 Pfam PF09722 Protein of unknown function (DUF2384) 100 149 1.9E-12 T 29-03-2018 IPR024467 Domain of unknown function DUF2384 THSYN_RS17190 eb67954172bc000d0febec2a57baaa48 152 TIGRFAM TIGR02293 TAS_TIGR02293: putative toxin-antitoxin system antitoxin component, TIGR02293 family 23 152 3.9E-33 T 29-03-2018 IPR011979 Conserved hypothetical protein CHP02293 THSYN_RS17190 eb67954172bc000d0febec2a57baaa48 152 Gene3D G3DSA:1.10.260.40 47 134 3.1E-5 T 29-03-2018 THSYN_RS21485 751c6745d76e9a17d0dd04e6eea4381a 196 Hamap MF_00052_B Ribonuclease HII [rnhB]. 10 189 38.194 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 THSYN_RS21485 751c6745d76e9a17d0dd04e6eea4381a 196 Pfam PF01351 Ribonuclease HII 12 188 2.6E-38 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain THSYN_RS21485 751c6745d76e9a17d0dd04e6eea4381a 196 SUPERFAMILY SSF53098 7 194 5.61E-68 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS21485 751c6745d76e9a17d0dd04e6eea4381a 196 Gene3D G3DSA:3.30.420.10 3 196 5.4E-69 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS28550 e6772ed9c3a871017fc3348495ef466a 312 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 37 284 4.7E-85 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 THSYN_RS28550 e6772ed9c3a871017fc3348495ef466a 312 Pfam PF02355 Protein export membrane protein 117 291 1.2E-66 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial THSYN_RS28550 e6772ed9c3a871017fc3348495ef466a 312 PRINTS PR01755 Bacterial translocase SecF protein signature 232 247 8.6E-33 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THSYN_RS28550 e6772ed9c3a871017fc3348495ef466a 312 PRINTS PR01755 Bacterial translocase SecF protein signature 152 166 8.6E-33 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THSYN_RS28550 e6772ed9c3a871017fc3348495ef466a 312 PRINTS PR01755 Bacterial translocase SecF protein signature 200 218 8.6E-33 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THSYN_RS28550 e6772ed9c3a871017fc3348495ef466a 312 PRINTS PR01755 Bacterial translocase SecF protein signature 36 51 8.6E-33 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THSYN_RS28550 e6772ed9c3a871017fc3348495ef466a 312 Pfam PF07549 SecD/SecF GG Motif 32 58 8.3E-10 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site THSYN_RS28550 e6772ed9c3a871017fc3348495ef466a 312 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 117 281 4.5E-56 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THSYN_RS28550 e6772ed9c3a871017fc3348495ef466a 312 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 9 295 29.384 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 THSYN_RS28550 e6772ed9c3a871017fc3348495ef466a 312 SUPERFAMILY SSF82866 73 292 7.72E-39 T 29-03-2018 THSYN_RS28550 e6772ed9c3a871017fc3348495ef466a 312 Gene3D G3DSA:1.20.1640.10 62 297 1.8E-28 T 29-03-2018 THSYN_RS12675 e57dd07d0ff38d67876d0a8d1ef0e120 148 Gene3D G3DSA:1.10.260.40 42 110 8.0E-5 T 29-03-2018 THSYN_RS12675 e57dd07d0ff38d67876d0a8d1ef0e120 148 Pfam PF09722 Protein of unknown function (DUF2384) 96 145 5.9E-17 T 29-03-2018 IPR024467 Domain of unknown function DUF2384 THSYN_RS12675 e57dd07d0ff38d67876d0a8d1ef0e120 148 TIGRFAM TIGR02293 TAS_TIGR02293: putative toxin-antitoxin system antitoxin component, TIGR02293 family 22 148 1.3E-25 T 29-03-2018 IPR011979 Conserved hypothetical protein CHP02293 THSYN_RS25330 96c806bbb1250bd9bf5bcafb890c0401 336 Pfam PF12784 PD-(D/E)XK nuclease family transposase 26 253 1.3E-33 T 29-03-2018 THSYN_RS25330 96c806bbb1250bd9bf5bcafb890c0401 336 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 27 277 8.7E-33 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA THSYN_RS24605 98c8df4e165a3a2773c529e58f365b30 344 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 10 337 25.422 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24605 98c8df4e165a3a2773c529e58f365b30 344 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 214 227 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24605 98c8df4e165a3a2773c529e58f365b30 344 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 56 71 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24605 98c8df4e165a3a2773c529e58f365b30 344 Pfam PF00146 NADH dehydrogenase 17 330 3.6E-127 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS22840 1847ce9e77ada059f7597532a9f73fcb 147 Gene3D G3DSA:2.60.40.790 4 127 5.8E-21 T 29-03-2018 IPR008978 HSP20-like chaperone THSYN_RS22840 1847ce9e77ada059f7597532a9f73fcb 147 Pfam PF00011 Hsp20/alpha crystallin family 31 126 3.2E-19 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain THSYN_RS22840 1847ce9e77ada059f7597532a9f73fcb 147 SUPERFAMILY SSF49764 13 126 1.78E-21 T 29-03-2018 IPR008978 HSP20-like chaperone THSYN_RS06985 302040a832140dcc1a551bf82a1a67ba 147 Pfam PF01814 Hemerythrin HHE cation binding domain 5 135 2.0E-6 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THSYN_RS06985 302040a832140dcc1a551bf82a1a67ba 147 Gene3D G3DSA:1.20.120.520 86 141 0.25 T 29-03-2018 THSYN_RS06985 302040a832140dcc1a551bf82a1a67ba 147 Gene3D G3DSA:1.20.120.520 2 85 1.8E-4 T 29-03-2018 THSYN_RS05635 71c60a984819c2168d7ff17884a92760 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 27.42 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS05635 71c60a984819c2168d7ff17884a92760 156 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 1 155 8.1E-46 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS05635 71c60a984819c2168d7ff17884a92760 156 PIRSF PIRSF004505 1 155 4.2E-41 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS05635 71c60a984819c2168d7ff17884a92760 156 SUPERFAMILY SSF75217 2 154 7.19E-46 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases THSYN_RS05635 71c60a984819c2168d7ff17884a92760 156 Pfam PF02590 Predicted SPOUT methyltransferase 2 154 3.1E-45 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THSYN_RS05635 71c60a984819c2168d7ff17884a92760 156 Gene3D G3DSA:3.40.1280.10 1 155 3.2E-48 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THSYN_RS25685 6fdb87f30d4ab88df1e41c8f9b803bdf 419 Gene3D G3DSA:3.40.50.300 87 385 4.4E-5 T 29-03-2018 THSYN_RS06950 63fb354d1cf0f9a8e0185411e0a29c07 143 Pfam PF13279 Thioesterase-like superfamily 13 130 2.6E-13 T 29-03-2018 THSYN_RS06950 63fb354d1cf0f9a8e0185411e0a29c07 143 SUPERFAMILY SSF54637 5 130 6.6E-29 T 29-03-2018 IPR029069 HotDog domain THSYN_RS06950 63fb354d1cf0f9a8e0185411e0a29c07 143 Gene3D G3DSA:3.10.129.10 3 139 1.6E-24 T 29-03-2018 THSYN_RS08155 7e6543b45ee5119eeb15560d24c50699 84 Gene3D G3DSA:1.10.1220.10 2 35 4.2E-4 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS03855 da542a68e6cd0cbc333b2606cbc4ff87 666 SUPERFAMILY SSF48317 247 440 4.25E-17 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS03855 da542a68e6cd0cbc333b2606cbc4ff87 666 Pfam PF09335 SNARE associated Golgi protein 39 159 2.9E-13 T 29-03-2018 IPR032816 SNARE associated Golgi protein THSYN_RS03855 da542a68e6cd0cbc333b2606cbc4ff87 666 Pfam PF14067 LssY C-terminus 498 611 4.1E-14 T 29-03-2018 IPR025902 LssY-like C-terminal domain THSYN_RS03855 da542a68e6cd0cbc333b2606cbc4ff87 666 Gene3D G3DSA:1.20.144.10 254 457 8.4E-10 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THSYN_RS16415 82843d4f640a7cee32407f4f5516f74a 79 Gene3D G3DSA:3.40.50.10140 1 73 4.5E-12 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS16415 82843d4f640a7cee32407f4f5516f74a 79 SUPERFAMILY SSF52200 3 61 5.49E-12 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS16415 82843d4f640a7cee32407f4f5516f74a 79 Pfam PF13676 TIR domain 7 66 2.0E-11 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS01450 6de24acfbfc58ed12adab92110a2832e 323 SMART SM00267 135 308 1.2E-58 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS01450 6de24acfbfc58ed12adab92110a2832e 323 Pfam PF00990 Diguanylate cyclase, GGDEF domain 146 304 3.5E-45 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS01450 6de24acfbfc58ed12adab92110a2832e 323 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 144 307 2.1E-38 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS01450 6de24acfbfc58ed12adab92110a2832e 323 SUPERFAMILY SSF55073 151 310 1.57E-47 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS01450 6de24acfbfc58ed12adab92110a2832e 323 Pfam PF00072 Response regulator receiver domain 11 121 1.2E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS01450 6de24acfbfc58ed12adab92110a2832e 323 Gene3D G3DSA:3.40.50.2300 1 142 9.4E-31 T 29-03-2018 THSYN_RS01450 6de24acfbfc58ed12adab92110a2832e 323 Gene3D G3DSA:3.30.70.270 143 316 8.6E-57 T 29-03-2018 THSYN_RS01450 6de24acfbfc58ed12adab92110a2832e 323 SUPERFAMILY SSF52172 8 144 5.98E-33 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS01450 6de24acfbfc58ed12adab92110a2832e 323 SMART SM00448 9 122 3.5E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS31970 269eaaa36788b9ad0b7e1346b2a909bf 288 SUPERFAMILY SSF56935 12 211 8.01E-9 T 29-03-2018 THSYN_RS31970 269eaaa36788b9ad0b7e1346b2a909bf 288 Gene3D G3DSA:2.40.160.40 117 261 1.6E-6 T 29-03-2018 THSYN_RS31970 269eaaa36788b9ad0b7e1346b2a909bf 288 Gene3D G3DSA:2.40.128.130 5 116 5.8E-6 T 29-03-2018 THSYN_RS26225 d4af1cacff74f97baceb93063388584c 690 Pfam PF02554 Carbon starvation protein CstA 34 410 2.6E-168 T 29-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 THSYN_RS26225 d4af1cacff74f97baceb93063388584c 690 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 465 593 5.5E-33 T 29-03-2018 IPR025299 CstA, C-terminal domain THSYN_RS02800 0e83909688b3526e5ba0af3f1d23be3d 449 Pfam PF01523 Putative modulator of DNA gyrase 35 326 2.2E-58 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 THSYN_RS02800 0e83909688b3526e5ba0af3f1d23be3d 449 SUPERFAMILY SSF111283 15 448 4.84E-122 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 THSYN_RS02800 0e83909688b3526e5ba0af3f1d23be3d 449 Gene3D G3DSA:3.30.2290.10 1 235 2.2E-60 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain THSYN_RS15340 465ada27ce454dbb28846e9adcd74783 94 SUPERFAMILY SSF81301 5 93 1.05E-19 T 29-03-2018 THSYN_RS15340 465ada27ce454dbb28846e9adcd74783 94 Gene3D G3DSA:3.30.460.10 1 94 1.4E-20 T 29-03-2018 THSYN_RS15340 465ada27ce454dbb28846e9adcd74783 94 Pfam PF01909 Nucleotidyltransferase domain 10 92 3.0E-13 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS31215 fe8d2056b426bf1962955d3444796334 155 Pfam PF07885 Ion channel 77 148 6.5E-10 T 29-03-2018 IPR013099 Potassium channel domain THSYN_RS31215 fe8d2056b426bf1962955d3444796334 155 Gene3D G3DSA:1.10.287.70 51 154 2.9E-12 T 29-03-2018 THSYN_RS31215 fe8d2056b426bf1962955d3444796334 155 SUPERFAMILY SSF81324 65 147 4.84E-10 T 29-03-2018 THSYN_RS03405 492abafbd99321d44cc71f7f2c424886 263 SMART SM00271 209 263 1.6E-8 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS03405 492abafbd99321d44cc71f7f2c424886 263 SUPERFAMILY SSF46565 205 260 1.11E-14 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS03405 492abafbd99321d44cc71f7f2c424886 263 Gene3D G3DSA:1.10.287.110 206 261 2.6E-12 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS06495 5f5362bda577f9dcdc7900cb680e8f2a 229 Gene3D G3DSA:3.90.1580.10 62 226 2.6E-55 T 29-03-2018 THSYN_RS06495 5f5362bda577f9dcdc7900cb680e8f2a 229 Gene3D G3DSA:3.90.1580.10 1 61 1.3E-11 T 29-03-2018 THSYN_RS06495 5f5362bda577f9dcdc7900cb680e8f2a 229 Pfam PF03781 Sulfatase-modifying factor enzyme 1 1 222 2.5E-55 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS06495 5f5362bda577f9dcdc7900cb680e8f2a 229 SUPERFAMILY SSF56436 1 222 1.48E-70 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS01210 1ae44f3f181fd718bfb33bcaffb0cd13 212 Gene3D G3DSA:2.130.10.130 72 199 5.2E-4 T 29-03-2018 THSYN_RS12940 fffca6a0ea35d339d024cbb4755a9847 71 SMART SM00899 1 69 2.8E-19 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 THSYN_RS12940 fffca6a0ea35d339d024cbb4755a9847 71 Gene3D G3DSA:2.30.30.90 1 71 1.9E-21 T 29-03-2018 THSYN_RS12940 fffca6a0ea35d339d024cbb4755a9847 71 Pfam PF04023 FeoA domain 1 69 4.8E-18 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 THSYN_RS12940 fffca6a0ea35d339d024cbb4755a9847 71 SUPERFAMILY SSF50037 2 69 2.98E-20 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal THSYN_RS16655 8f1f6073363b5221e7d8b99264d2b547 87 SUPERFAMILY SSF47598 3 43 4.37E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS16655 8f1f6073363b5221e7d8b99264d2b547 87 Gene3D G3DSA:1.10.1220.10 1 77 1.3E-9 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS32830 b248c5112d2ecc568a4f7e74dbff1ce2 162 Pfam PF05638 Type VI secretion system effector, Hcp 6 136 7.8E-41 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp THSYN_RS32830 b248c5112d2ecc568a4f7e74dbff1ce2 162 Gene3D G3DSA:2.30.110.20 1 162 1.3E-49 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp THSYN_RS32830 b248c5112d2ecc568a4f7e74dbff1ce2 162 SUPERFAMILY SSF141452 2 161 1.83E-57 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp THSYN_RS21180 653c7cee5cd39fef8034ff0863dd4a70 83 SUPERFAMILY SSF143120 8 48 1.05E-9 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS21180 653c7cee5cd39fef8034ff0863dd4a70 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 8 48 5.9E-11 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS21180 653c7cee5cd39fef8034ff0863dd4a70 83 Gene3D G3DSA:3.40.1620.10 7 44 2.1E-14 T 29-03-2018 THSYN_RS21180 653c7cee5cd39fef8034ff0863dd4a70 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 47 3.2E-8 T 29-03-2018 THSYN_RS21375 da8b1c141b80c4dfa60fa7a65d3470c4 149 PRINTS PR00618 DksA/TraR zinc finger signature 125 137 4.5E-5 T 29-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria THSYN_RS21375 da8b1c141b80c4dfa60fa7a65d3470c4 149 PRINTS PR00618 DksA/TraR zinc finger signature 113 124 4.5E-5 T 29-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria THSYN_RS21375 da8b1c141b80c4dfa60fa7a65d3470c4 149 SUPERFAMILY SSF109635 15 108 3.14E-34 T 29-03-2018 THSYN_RS21375 da8b1c141b80c4dfa60fa7a65d3470c4 149 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 110 139 3.1E-11 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 THSYN_RS21375 da8b1c141b80c4dfa60fa7a65d3470c4 149 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 113 137 - T 29-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site THSYN_RS21375 da8b1c141b80c4dfa60fa7a65d3470c4 149 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 31 139 5.7E-52 T 29-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 THSYN_RS21375 da8b1c141b80c4dfa60fa7a65d3470c4 149 SUPERFAMILY SSF57716 110 147 9.27E-10 T 29-03-2018 THSYN_RS21375 da8b1c141b80c4dfa60fa7a65d3470c4 149 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 27 149 30.198 T 29-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 THSYN_RS21580 fece49ab2db0f8c5c87aab8a4b43414e 161 SUPERFAMILY SSF53146 20 138 1.57E-29 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THSYN_RS21580 fece49ab2db0f8c5c87aab8a4b43414e 161 Gene3D G3DSA:3.30.420.130 16 140 1.9E-31 T 29-03-2018 THSYN_RS21580 fece49ab2db0f8c5c87aab8a4b43414e 161 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 34 125 3.7E-19 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THSYN_RS31690 3adcea4f5b475de10276319b2de80af5 536 SUPERFAMILY SSF53807 3 442 8.18E-104 T 29-03-2018 THSYN_RS31690 3adcea4f5b475de10276319b2de80af5 536 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 13 423 3.5E-76 T 29-03-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 THSYN_RS31690 3adcea4f5b475de10276319b2de80af5 536 Gene3D G3DSA:3.40.50.1980 294 446 1.2E-22 T 29-03-2018 THSYN_RS31690 3adcea4f5b475de10276319b2de80af5 536 TIGRFAM TIGR01278 DPOR_BchB: light-independent protochlorophyllide reductase, B subunit 1 535 1.1E-184 T 29-03-2018 IPR005969 Light-independent protochlorophyllide reductase, B subunit GO:0015995|GO:0016730|GO:0019685|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31690 3adcea4f5b475de10276319b2de80af5 536 Pfam PF08369 Proto-chlorophyllide reductase 57 kD subunit 487 531 1.3E-19 T 29-03-2018 IPR013580 Proto-chlorophyllide/chlorophyllide reductase, C-terminal GO:0015979|GO:0015995|GO:0016491|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31690 3adcea4f5b475de10276319b2de80af5 536 PIRSF PIRSF000163 1 536 8.8E-203 T 29-03-2018 IPR016209 Protochlorophyllide reductase, ChlB, light independent GO:0016730|GO:0046148|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31690 3adcea4f5b475de10276319b2de80af5 536 Gene3D G3DSA:3.40.50.1980 11 137 1.3E-21 T 29-03-2018 THSYN_RS31690 3adcea4f5b475de10276319b2de80af5 536 Hamap MF_00353 Light-independent protochlorophyllide reductase subunit B [bchB]. 1 535 50.751 T 29-03-2018 IPR005969 Light-independent protochlorophyllide reductase, B subunit GO:0015995|GO:0016730|GO:0019685|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31690 3adcea4f5b475de10276319b2de80af5 536 Gene3D G3DSA:3.40.50.1980 138 284 4.5E-30 T 29-03-2018 THSYN_RS24010 22c0060757bd0d75e5db3874b614a6a2 64 PRINTS PR00064 Ribosomal protein L35 signature 35 53 2.6E-18 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THSYN_RS24010 22c0060757bd0d75e5db3874b614a6a2 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 2.6E-18 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THSYN_RS24010 22c0060757bd0d75e5db3874b614a6a2 64 PRINTS PR00064 Ribosomal protein L35 signature 20 34 2.6E-18 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THSYN_RS24010 22c0060757bd0d75e5db3874b614a6a2 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 30 - T 29-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS24010 22c0060757bd0d75e5db3874b614a6a2 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 1.2E-22 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THSYN_RS24010 22c0060757bd0d75e5db3874b614a6a2 64 SUPERFAMILY SSF143034 2 63 3.53E-20 T 29-03-2018 THSYN_RS24010 22c0060757bd0d75e5db3874b614a6a2 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 63 16.953 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THSYN_RS24010 22c0060757bd0d75e5db3874b614a6a2 64 Pfam PF01632 Ribosomal protein L35 2 60 5.4E-21 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS17050 f49b3319cf4c21fce5bbbf86e2f585f3 415 Pfam PF13641 Glycosyltransferase like family 2 60 282 2.4E-21 T 29-03-2018 THSYN_RS17050 f49b3319cf4c21fce5bbbf86e2f585f3 415 Gene3D G3DSA:3.90.550.10 26 307 2.5E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS17050 f49b3319cf4c21fce5bbbf86e2f585f3 415 SUPERFAMILY SSF53448 46 310 7.69E-37 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS24250 360da4090631b94f76f52cbd05bc7c41 371 SUPERFAMILY SSF51126 49 283 6.28E-7 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS21405 0cbe0de4333ad8579da5e3cd857d2b6d 196 Gene3D G3DSA:2.60.40.790 36 179 7.1E-8 T 29-03-2018 IPR008978 HSP20-like chaperone THSYN_RS21405 0cbe0de4333ad8579da5e3cd857d2b6d 196 SUPERFAMILY SSF49764 72 174 5.58E-6 T 29-03-2018 IPR008978 HSP20-like chaperone THSYN_RS09640 631361e12e713fbb58bf63793a2e29fd 69 SMART SM00966 4 49 3.8E-6 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS09640 631361e12e713fbb58bf63793a2e29fd 69 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 44 8.8E-8 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS09640 631361e12e713fbb58bf63793a2e29fd 69 SUPERFAMILY SSF89447 2 45 1.33E-7 T 29-03-2018 THSYN_RS09640 631361e12e713fbb58bf63793a2e29fd 69 Gene3D G3DSA:2.10.260.10 4 46 6.5E-7 T 29-03-2018 THSYN_RS06400 7eb4e19b7662c8c7891f3247c5b18b48 947 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 691 737 1.4E-7 T 29-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat THSYN_RS16380 aa2af8421c1abed849562e86e1c1f320 435 ProSitePatterns PS00161 Isocitrate lyase signature. 193 198 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 THSYN_RS16380 aa2af8421c1abed849562e86e1c1f320 435 PIRSF PIRSF001362 1 435 7.1E-212 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 THSYN_RS16380 aa2af8421c1abed849562e86e1c1f320 435 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 9 257 3.2E-106 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 THSYN_RS16380 aa2af8421c1abed849562e86e1c1f320 435 Gene3D G3DSA:3.20.20.60 1 417 1.2E-144 T 29-03-2018 THSYN_RS16380 aa2af8421c1abed849562e86e1c1f320 435 SUPERFAMILY SSF51621 7 434 9.87E-146 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS16380 aa2af8421c1abed849562e86e1c1f320 435 Pfam PF00463 Isocitrate lyase family 13 256 2.1E-56 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 THSYN_RS09415 fe199acc21a5a6b9cd56550b12065ac5 593 Pfam PF03235 Protein of unknown function DUF262 11 234 1.1E-24 T 29-03-2018 IPR004919 Domain of unknown function DUF262 THSYN_RS28700 bbe03c8a3809547b0d8bffaa404ce029 245 SMART SM00862 152 227 4.0E-17 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS28700 bbe03c8a3809547b0d8bffaa404ce029 245 Gene3D G3DSA:1.10.10.10 119 233 6.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS28700 bbe03c8a3809547b0d8bffaa404ce029 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 227 8.2E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS28700 bbe03c8a3809547b0d8bffaa404ce029 245 Gene3D G3DSA:3.40.50.2300 2 118 2.7E-31 T 29-03-2018 THSYN_RS28700 bbe03c8a3809547b0d8bffaa404ce029 245 SMART SM00448 3 113 1.0E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS28700 bbe03c8a3809547b0d8bffaa404ce029 245 SUPERFAMILY SSF46894 141 227 3.97E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS28700 bbe03c8a3809547b0d8bffaa404ce029 245 Pfam PF00072 Response regulator receiver domain 5 113 5.5E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS28700 bbe03c8a3809547b0d8bffaa404ce029 245 SUPERFAMILY SSF52172 2 125 1.31E-36 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS13010 fd6c13e03a3b3659c7d55160a6202b66 702 Gene3D G3DSA:3.90.550.10 77 367 1.8E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS13010 fd6c13e03a3b3659c7d55160a6202b66 702 SUPERFAMILY SSF53448 103 389 1.13E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS13010 fd6c13e03a3b3659c7d55160a6202b66 702 Pfam PF13632 Glycosyl transferase family group 2 201 396 1.2E-17 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS18780 06fd967364403738bba770d33e7c2c2c 1368 Gene3D G3DSA:3.90.1580.10 1094 1368 2.5E-74 T 29-03-2018 THSYN_RS18780 06fd967364403738bba770d33e7c2c2c 1368 Pfam PF03781 Sulfatase-modifying factor enzyme 1 1102 1365 7.0E-64 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS18780 06fd967364403738bba770d33e7c2c2c 1368 SUPERFAMILY SSF56436 1102 1367 4.24E-70 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS14105 b3730f42db543efc3afaddfd9fa93661 730 SMART SM00642 140 630 9.4E-42 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THSYN_RS14105 b3730f42db543efc3afaddfd9fa93661 730 Pfam PF16738 Starch-binding module 26 16 83 1.2E-13 T 29-03-2018 IPR031965 Starch-binding module 26 KEGG: 00500+3.2.1.1 THSYN_RS14105 b3730f42db543efc3afaddfd9fa93661 730 Pfam PF00128 Alpha amylase, catalytic domain 176 257 2.5E-23 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THSYN_RS14105 b3730f42db543efc3afaddfd9fa93661 730 Pfam PF00128 Alpha amylase, catalytic domain 385 448 5.9E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THSYN_RS14105 b3730f42db543efc3afaddfd9fa93661 730 SUPERFAMILY SSF51445 355 637 2.98E-68 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS14105 b3730f42db543efc3afaddfd9fa93661 730 SUPERFAMILY SSF51445 132 283 2.98E-68 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS14105 b3730f42db543efc3afaddfd9fa93661 730 Gene3D G3DSA:3.20.20.80 128 636 4.8E-75 T 29-03-2018 THSYN_RS14105 b3730f42db543efc3afaddfd9fa93661 730 Gene3D G3DSA:2.60.40.1180 655 717 3.9E-5 T 29-03-2018 THSYN_RS24085 eef9a667bb5efda2c8010a03677094c3 259 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 6 256 2.7E-91 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 THSYN_RS24085 eef9a667bb5efda2c8010a03677094c3 259 Pfam PF00753 Metallo-beta-lactamase superfamily 13 169 3.7E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS24085 eef9a667bb5efda2c8010a03677094c3 259 SMART SM00849 12 169 8.1E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS24085 eef9a667bb5efda2c8010a03677094c3 259 Gene3D G3DSA:3.60.15.10 1 256 3.7E-60 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS24085 eef9a667bb5efda2c8010a03677094c3 259 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 170 255 5.9E-23 T 29-03-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 THSYN_RS24085 eef9a667bb5efda2c8010a03677094c3 259 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 2 257 40.295 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 THSYN_RS24085 eef9a667bb5efda2c8010a03677094c3 259 SUPERFAMILY SSF56281 4 256 3.08E-61 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS24085 eef9a667bb5efda2c8010a03677094c3 259 PIRSF PIRSF005457 1 257 5.5E-83 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 THSYN_RS03440 6a2212029bf2c52d21a91d53d02550a7 971 Gene3D G3DSA:3.40.50.150 68 722 5.0E-27 T 29-03-2018 THSYN_RS03440 6a2212029bf2c52d21a91d53d02550a7 971 Pfam PF06634 Protein of unknown function (DUF1156) 11 82 2.6E-33 T 29-03-2018 IPR009537 Domain of unknown function DUF1156 THSYN_RS29030 2bf762dff5382a0ec038c1119c35f5b2 329 Gene3D G3DSA:3.90.550.10 2 227 3.9E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS29030 2bf762dff5382a0ec038c1119c35f5b2 329 SUPERFAMILY SSF53448 4 207 1.08E-49 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS29030 2bf762dff5382a0ec038c1119c35f5b2 329 Pfam PF00535 Glycosyl transferase family 2 7 114 2.0E-23 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS14770 a8e64e64bfb0aa708db89e09a8efd1dc 145 Pfam PF01724 Domain of unknown function DUF29 4 140 2.7E-47 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS31060 77cdef24977953190251978da5a3564d 98 Pfam PF13744 Helix-turn-helix domain 20 92 3.8E-15 T 29-03-2018 THSYN_RS31060 77cdef24977953190251978da5a3564d 98 SUPERFAMILY SSF47413 23 92 4.5E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS31060 77cdef24977953190251978da5a3564d 98 Gene3D G3DSA:1.10.260.40 8 97 1.2E-5 T 29-03-2018 THSYN_RS04320 f1e34cfd9ff7d2963c8bbb31017f5184 546 SUPERFAMILY SSF51395 99 233 3.89E-44 T 29-03-2018 THSYN_RS04320 f1e34cfd9ff7d2963c8bbb31017f5184 546 SUPERFAMILY SSF51395 261 533 3.89E-44 T 29-03-2018 THSYN_RS04320 f1e34cfd9ff7d2963c8bbb31017f5184 546 Pfam PF01645 Conserved region in glutamate synthase 294 418 2.6E-10 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 THSYN_RS04320 f1e34cfd9ff7d2963c8bbb31017f5184 546 Gene3D G3DSA:3.20.20.70 99 540 1.4E-44 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS11455 7a97d46fe997d7272c947e13a1e00cb5 142 PIRSF PIRSF009151 1 127 1.0E-59 T 29-03-2018 IPR008497 Protein of unknown function DUF779 THSYN_RS11455 7a97d46fe997d7272c947e13a1e00cb5 142 Pfam PF05610 Protein of unknown function (DUF779) 19 112 4.9E-46 T 29-03-2018 IPR008497 Protein of unknown function DUF779 THSYN_RS14425 9b1c42b0dbe31f95337253100b3e9bbf 355 Pfam PF09344 CT1975-like protein 56 343 2.7E-32 T 29-03-2018 IPR010148 CRISPR-associated protein, CT1975 THSYN_RS00720 313748f8abe7500df90813c5072ed478 287 Gene3D G3DSA:1.10.101.10 1 48 8.4E-7 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS00720 313748f8abe7500df90813c5072ed478 287 SUPERFAMILY SSF47090 2 40 6.12E-6 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS00720 313748f8abe7500df90813c5072ed478 287 Gene3D G3DSA:3.40.390.10 55 278 2.4E-13 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 THSYN_RS00720 313748f8abe7500df90813c5072ed478 287 SUPERFAMILY SSF55486 218 275 7.57E-5 T 29-03-2018 THSYN_RS10600 289f3120126af44969a7465a4196a76b 350 Pfam PF02562 PhoH-like protein 114 317 6.8E-93 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 THSYN_RS10600 289f3120126af44969a7465a4196a76b 350 Gene3D G3DSA:3.40.50.300 113 317 4.0E-29 T 29-03-2018 THSYN_RS10600 289f3120126af44969a7465a4196a76b 350 SUPERFAMILY SSF52540 117 292 1.97E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21260 7530b6717f6cf83d131f30d4eb84e86c 668 SMART SM00052 398 649 2.8E-64 T 29-03-2018 IPR001633 EAL domain THSYN_RS21260 7530b6717f6cf83d131f30d4eb84e86c 668 Gene3D G3DSA:3.20.20.450 400 656 5.1E-71 T 29-03-2018 IPR001633 EAL domain THSYN_RS21260 7530b6717f6cf83d131f30d4eb84e86c 668 Pfam PF00563 EAL domain 406 642 1.8E-55 T 29-03-2018 IPR001633 EAL domain THSYN_RS21260 7530b6717f6cf83d131f30d4eb84e86c 668 SUPERFAMILY SSF55073 231 388 7.77E-38 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS21260 7530b6717f6cf83d131f30d4eb84e86c 668 SUPERFAMILY SSF55785 117 222 2.03E-7 T 29-03-2018 IPR000014 PAS domain THSYN_RS21260 7530b6717f6cf83d131f30d4eb84e86c 668 SMART SM00267 215 386 4.6E-40 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS21260 7530b6717f6cf83d131f30d4eb84e86c 668 Gene3D G3DSA:3.30.450.20 87 221 8.6E-10 T 29-03-2018 THSYN_RS21260 7530b6717f6cf83d131f30d4eb84e86c 668 Pfam PF00990 Diguanylate cyclase, GGDEF domain 227 381 8.4E-31 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS21260 7530b6717f6cf83d131f30d4eb84e86c 668 Gene3D G3DSA:3.30.70.270 222 389 9.9E-45 T 29-03-2018 THSYN_RS21260 7530b6717f6cf83d131f30d4eb84e86c 668 SUPERFAMILY SSF141868 405 650 1.44E-64 T 29-03-2018 IPR001633 EAL domain THSYN_RS21260 7530b6717f6cf83d131f30d4eb84e86c 668 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 225 382 5.8E-30 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS10490 2e29faadcc4af432e4fc81a98f12c8ea 81 Pfam PF10387 Protein of unknown function (DUF2442) 8 73 2.2E-13 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS01220 487d95d839a465d247d971d1817a20c0 279 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 3 254 1.6E-75 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 THSYN_RS01220 487d95d839a465d247d971d1817a20c0 279 Gene3D G3DSA:3.40.50.150 1 201 4.2E-50 T 29-03-2018 THSYN_RS01220 487d95d839a465d247d971d1817a20c0 279 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 2 257 53.313 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 THSYN_RS01220 487d95d839a465d247d971d1817a20c0 279 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 34 61 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 THSYN_RS01220 487d95d839a465d247d971d1817a20c0 279 SUPERFAMILY SSF53335 1 256 4.94E-73 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS01220 487d95d839a465d247d971d1817a20c0 279 Gene3D G3DSA:1.10.8.100 202 259 3.0E-19 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 THSYN_RS01220 487d95d839a465d247d971d1817a20c0 279 Pfam PF00398 Ribosomal RNA adenine dimethylase 2 256 7.6E-54 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm THSYN_RS01220 487d95d839a465d247d971d1817a20c0 279 SMART SM00650 18 190 6.4E-80 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 THSYN_RS16465 984f587acb501dc25df8e3c24251183f 464 Pfam PF00535 Glycosyl transferase family 2 137 249 6.2E-19 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS16465 984f587acb501dc25df8e3c24251183f 464 SUPERFAMILY SSF53448 136 353 4.88E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS16465 984f587acb501dc25df8e3c24251183f 464 Gene3D G3DSA:3.90.550.10 118 408 1.9E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22555 944ce1c704a216dde873a09ac862ead4 59 Pfam PF04995 Heme exporter protein D (CcmD) 11 51 8.3E-13 T 29-03-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 THSYN_RS22555 944ce1c704a216dde873a09ac862ead4 59 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 11 51 1.3E-11 T 29-03-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 THSYN_RS23045 a9a1b8a34af9b86e391a050f1025221a 373 Gene3D G3DSA:3.90.1580.10 117 184 1.1E-13 T 29-03-2018 THSYN_RS23045 a9a1b8a34af9b86e391a050f1025221a 373 Gene3D G3DSA:3.90.1580.10 185 371 3.2E-46 T 29-03-2018 THSYN_RS23045 a9a1b8a34af9b86e391a050f1025221a 373 Pfam PF03781 Sulfatase-modifying factor enzyme 1 124 365 4.1E-51 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS23045 a9a1b8a34af9b86e391a050f1025221a 373 SUPERFAMILY SSF56436 123 365 6.83E-61 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS07735 bafbfe09e3f54579b2966bf7dab56144 198 Gene3D G3DSA:3.40.1800.10 5 65 4.6E-6 T 29-03-2018 THSYN_RS19605 9a43eeca6ade7a5bd9c0321b54cedab9 269 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 239 261 9.1E-12 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal THSYN_RS19605 9a43eeca6ade7a5bd9c0321b54cedab9 269 Pfam PF00005 ABC transporter 30 190 6.2E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS19605 9a43eeca6ade7a5bd9c0321b54cedab9 269 SUPERFAMILY SSF52540 13 261 1.78E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19605 9a43eeca6ade7a5bd9c0321b54cedab9 269 SMART SM00382 39 239 2.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS19605 9a43eeca6ade7a5bd9c0321b54cedab9 269 Gene3D G3DSA:3.40.50.300 9 264 3.7E-58 T 29-03-2018 THSYN_RS12075 8ffe426e2f18c5c0e82e0703f99c09b8 85 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 64 7.0E-6 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS12075 8ffe426e2f18c5c0e82e0703f99c09b8 85 Gene3D G3DSA:3.40.1620.10 1 50 1.8E-4 T 29-03-2018 THSYN_RS12075 8ffe426e2f18c5c0e82e0703f99c09b8 85 SUPERFAMILY SSF143120 1 60 2.49E-8 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS03250 1719eca2b4dc30bbd5bbdb8f923d7079 174 Gene3D G3DSA:3.40.50.300 4 174 1.7E-34 T 29-03-2018 THSYN_RS03250 1719eca2b4dc30bbd5bbdb8f923d7079 174 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 29-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 THSYN_RS03250 1719eca2b4dc30bbd5bbdb8f923d7079 174 PRINTS PR01100 Shikimate kinase family signature 31 44 3.5E-24 T 29-03-2018 THSYN_RS03250 1719eca2b4dc30bbd5bbdb8f923d7079 174 PRINTS PR01100 Shikimate kinase family signature 77 86 3.5E-24 T 29-03-2018 THSYN_RS03250 1719eca2b4dc30bbd5bbdb8f923d7079 174 PRINTS PR01100 Shikimate kinase family signature 7 22 3.5E-24 T 29-03-2018 THSYN_RS03250 1719eca2b4dc30bbd5bbdb8f923d7079 174 PRINTS PR01100 Shikimate kinase family signature 59 67 3.5E-24 T 29-03-2018 THSYN_RS03250 1719eca2b4dc30bbd5bbdb8f923d7079 174 PRINTS PR01100 Shikimate kinase family signature 98 115 3.5E-24 T 29-03-2018 THSYN_RS03250 1719eca2b4dc30bbd5bbdb8f923d7079 174 Pfam PF01202 Shikimate kinase 13 169 2.1E-53 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 THSYN_RS03250 1719eca2b4dc30bbd5bbdb8f923d7079 174 SUPERFAMILY SSF52540 6 169 2.83E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03250 1719eca2b4dc30bbd5bbdb8f923d7079 174 Hamap MF_00109 Shikimate kinase [aroK]. 4 170 30.007 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 THSYN_RS05165 85d25a521decb0f1c6e914c2f10bb884 232 Pfam PF01988 VIT family 17 224 2.9E-51 T 29-03-2018 IPR008217 Ccc1 family THSYN_RS29335 73795feadb83bc183e925b4525380b16 520 SUPERFAMILY SSF56300 51 278 2.23E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS29335 73795feadb83bc183e925b4525380b16 520 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 52 277 7.4E-50 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA THSYN_RS29335 73795feadb83bc183e925b4525380b16 520 SMART SM00854 51 277 1.0E-59 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA THSYN_RS29335 73795feadb83bc183e925b4525380b16 520 Gene3D G3DSA:3.60.21.10 42 288 7.2E-32 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS23390 db612d3819154fb2f68cfa40fb990fa7 248 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 25 241 1.2E-57 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase THSYN_RS23390 db612d3819154fb2f68cfa40fb990fa7 248 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 19 240 1.1E-76 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase THSYN_RS23390 db612d3819154fb2f68cfa40fb990fa7 248 Gene3D G3DSA:3.60.140.10 1 246 1.7E-90 T 29-03-2018 THSYN_RS23390 db612d3819154fb2f68cfa40fb990fa7 248 SUPERFAMILY SSF64438 4 241 1.3E-81 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic THSYN_RS23940 9cbc5461745e6d5ee94ed829d78d4eef 124 SUPERFAMILY SSF50249 3 123 9.42E-51 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS23940 9cbc5461745e6d5ee94ed829d78d4eef 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 6.9E-42 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23940 9cbc5461745e6d5ee94ed829d78d4eef 124 Gene3D G3DSA:2.40.50.140 1 124 1.4E-63 T 29-03-2018 THSYN_RS23940 9cbc5461745e6d5ee94ed829d78d4eef 124 PIRSF PIRSF002133 1 124 2.2E-53 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23940 9cbc5461745e6d5ee94ed829d78d4eef 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23940 9cbc5461745e6d5ee94ed829d78d4eef 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 5.5E-70 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23940 9cbc5461745e6d5ee94ed829d78d4eef 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 2.8E-60 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23940 9cbc5461745e6d5ee94ed829d78d4eef 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 2.8E-60 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23940 9cbc5461745e6d5ee94ed829d78d4eef 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 2.8E-60 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23940 9cbc5461745e6d5ee94ed829d78d4eef 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 2.8E-60 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23940 9cbc5461745e6d5ee94ed829d78d4eef 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 2.8E-60 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23940 9cbc5461745e6d5ee94ed829d78d4eef 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 2.8E-60 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23940 9cbc5461745e6d5ee94ed829d78d4eef 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.931 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS24385 b23a28faca4ebac509fe6e130790af81 426 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 34 210 2.9E-62 T 29-03-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 THSYN_RS24385 b23a28faca4ebac509fe6e130790af81 426 Pfam PF00534 Glycosyl transferases group 1 304 400 1.1E-9 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS24385 b23a28faca4ebac509fe6e130790af81 426 SUPERFAMILY SSF53756 57 418 3.84E-19 T 29-03-2018 THSYN_RS24385 b23a28faca4ebac509fe6e130790af81 426 Gene3D G3DSA:3.40.50.2000 24 163 0.14 T 29-03-2018 THSYN_RS24385 b23a28faca4ebac509fe6e130790af81 426 Gene3D G3DSA:3.40.50.2000 210 405 8.5E-24 T 29-03-2018 THSYN_RS21895 07388dea3d7e6d056968561b0d8a2fd4 152 Pfam PF13374 Tetratricopeptide repeat 136 152 0.016 T 29-03-2018 THSYN_RS21895 07388dea3d7e6d056968561b0d8a2fd4 152 SUPERFAMILY SSF48452 53 152 2.39E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS21895 07388dea3d7e6d056968561b0d8a2fd4 152 Pfam PF13424 Tetratricopeptide repeat 62 126 3.8E-15 T 29-03-2018 THSYN_RS21895 07388dea3d7e6d056968561b0d8a2fd4 152 Gene3D G3DSA:1.10.10.10 64 152 2.8E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07150 25a8a95100a18a3f0efd1410f0323150 417 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 259 358 7.2E-26 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II THSYN_RS07150 25a8a95100a18a3f0efd1410f0323150 417 SUPERFAMILY SSF52518 5 245 1.44E-63 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS07150 25a8a95100a18a3f0efd1410f0323150 417 Gene3D G3DSA:3.40.50.920 249 397 1.6E-21 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS07150 25a8a95100a18a3f0efd1410f0323150 417 Gene3D G3DSA:3.40.50.970 2 247 2.1E-46 T 29-03-2018 THSYN_RS07150 25a8a95100a18a3f0efd1410f0323150 417 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 17 230 4.8E-66 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 THSYN_RS07150 25a8a95100a18a3f0efd1410f0323150 417 SUPERFAMILY SSF52922 250 374 3.8E-28 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THSYN_RS06425 50e28d3ba78e3826aa73f7234ab692eb 235 Pfam PF00005 ABC transporter 25 176 9.9E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS06425 50e28d3ba78e3826aa73f7234ab692eb 235 SUPERFAMILY SSF52540 3 214 2.18E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06425 50e28d3ba78e3826aa73f7234ab692eb 235 SMART SM00382 30 227 1.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS06425 50e28d3ba78e3826aa73f7234ab692eb 235 Gene3D G3DSA:3.40.50.300 2 216 1.2E-38 T 29-03-2018 THSYN_RS33050 355c97568404ff2bd97ba1eea21e3973 184 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 10 176 5.0E-62 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 THSYN_RS33050 355c97568404ff2bd97ba1eea21e3973 184 Gene3D G3DSA:3.30.230.60 7 177 1.5E-61 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 THSYN_RS33050 355c97568404ff2bd97ba1eea21e3973 184 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 9 175 7.5E-44 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 THSYN_RS33050 355c97568404ff2bd97ba1eea21e3973 184 SUPERFAMILY SSF54211 4 177 6.52E-57 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS20360 0a8217f7bae2c9f48c4c5476a8433294 353 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 13 349 26.812 T 29-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS20360 0a8217f7bae2c9f48c4c5476a8433294 353 Gene3D G3DSA:3.30.2340.10 176 310 1.6E-31 T 29-03-2018 THSYN_RS20360 0a8217f7bae2c9f48c4c5476a8433294 353 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 19 247 2.5E-51 T 29-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS20360 0a8217f7bae2c9f48c4c5476a8433294 353 SUPERFAMILY SSF55120 13 347 2.45E-92 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS20360 0a8217f7bae2c9f48c4c5476a8433294 353 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 85 98 - T 29-03-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 THSYN_RS20360 0a8217f7bae2c9f48c4c5476a8433294 353 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 25 177 3.6E-44 T 29-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS20360 0a8217f7bae2c9f48c4c5476a8433294 353 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 181 344 1.9E-21 T 29-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THSYN_RS13830 efbbc5068042a6704af2cc746ad42399 206 Gene3D G3DSA:3.40.50.2020 8 181 1.2E-13 T 29-03-2018 THSYN_RS13830 efbbc5068042a6704af2cc746ad42399 206 SUPERFAMILY SSF53271 13 171 7.95E-19 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like THSYN_RS07230 4725f2780200ebe96aff2908957c332b 189 Gene3D G3DSA:3.40.50.150 14 187 4.3E-22 T 29-03-2018 THSYN_RS07230 4725f2780200ebe96aff2908957c332b 189 SUPERFAMILY SSF53335 17 178 1.03E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS07230 4725f2780200ebe96aff2908957c332b 189 Pfam PF13489 Methyltransferase domain 22 167 1.9E-15 T 29-03-2018 THSYN_RS24440 f78655f09abdd66f71e332620a9b08df 223 Gene3D G3DSA:1.10.260.40 113 190 0.02 T 29-03-2018 THSYN_RS24440 f78655f09abdd66f71e332620a9b08df 223 Pfam PF10123 Mu-like prophage I protein 29 176 9.7E-32 T 29-03-2018 IPR012106 Protease, Mu phage/prophage I type THSYN_RS33025 ecfd05c702b647516b2810f38b55c169 52 Pfam PF08770 Sulphur oxidation protein SoxZ 2 44 2.1E-7 T 29-03-2018 IPR014880 Sulphur oxidation protein SoxZ THSYN_RS33025 ecfd05c702b647516b2810f38b55c169 52 SUPERFAMILY SSF81296 1 47 1.4E-7 T 29-03-2018 IPR014756 Immunoglobulin E-set THSYN_RS33025 ecfd05c702b647516b2810f38b55c169 52 Gene3D G3DSA:2.60.40.10 1 46 4.9E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS13945 41155b03019f3e6ede9d1707bb26e7fb 486 Gene3D G3DSA:3.40.50.300 58 359 1.8E-18 T 29-03-2018 THSYN_RS13945 41155b03019f3e6ede9d1707bb26e7fb 486 Pfam PF00350 Dynamin family 61 228 2.9E-13 T 29-03-2018 IPR022812 Dynamin superfamily THSYN_RS13945 41155b03019f3e6ede9d1707bb26e7fb 486 SUPERFAMILY SSF52540 58 260 6.3E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02670 e262802ae6d75b33b0771d61a8df06c4 331 Gene3D G3DSA:1.25.10.10 2 324 2.1E-10 T 29-03-2018 IPR011989 Armadillo-like helical THSYN_RS02670 e262802ae6d75b33b0771d61a8df06c4 331 SUPERFAMILY SSF48371 28 249 2.92E-11 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS11320 08558bfdb0eda3ff3646b4c836fc6ae6 105 Pfam PF00034 Cytochrome c 25 105 8.1E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS11320 08558bfdb0eda3ff3646b4c836fc6ae6 105 SUPERFAMILY SSF46626 34 104 8.74E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS11320 08558bfdb0eda3ff3646b4c836fc6ae6 105 Gene3D G3DSA:1.10.760.10 21 104 1.9E-15 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS07935 d88bfdd64126b312188bad3075026a41 485 Gene3D G3DSA:1.10.287.1120 409 469 3.3E-8 T 29-03-2018 THSYN_RS07935 d88bfdd64126b312188bad3075026a41 485 Gene3D G3DSA:3.90.220.20 145 408 1.9E-22 T 29-03-2018 THSYN_RS07935 d88bfdd64126b312188bad3075026a41 485 Gene3D G3DSA:3.90.220.20 1 144 1.7E-16 T 29-03-2018 THSYN_RS07935 d88bfdd64126b312188bad3075026a41 485 Pfam PF01420 Type I restriction modification DNA specificity domain 31 135 1.5E-5 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS07935 d88bfdd64126b312188bad3075026a41 485 SUPERFAMILY SSF116734 234 455 1.01E-28 T 29-03-2018 THSYN_RS07935 d88bfdd64126b312188bad3075026a41 485 SUPERFAMILY SSF116734 22 172 3.76E-22 T 29-03-2018 THSYN_RS08885 c4c618a576412cc6fc38b9284d31a070 621 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 198 512 6.8E-35 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 THSYN_RS08885 c4c618a576412cc6fc38b9284d31a070 621 ProSitePatterns PS00018 EF-hand calcium-binding domain. 295 307 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS08885 c4c618a576412cc6fc38b9284d31a070 621 Pfam PF05547 Immune inhibitor A peptidase M6 288 458 7.5E-7 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 THSYN_RS14300 394cfe06a832c845b57c4f58f75f1266 93 Pfam PF13744 Helix-turn-helix domain 19 91 2.0E-13 T 29-03-2018 THSYN_RS14300 394cfe06a832c845b57c4f58f75f1266 93 Gene3D G3DSA:1.10.10.10 16 52 0.0015 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS14300 394cfe06a832c845b57c4f58f75f1266 93 SUPERFAMILY SSF47413 23 90 1.13E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS14300 394cfe06a832c845b57c4f58f75f1266 93 SMART SM00530 34 90 0.0023 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS14300 394cfe06a832c845b57c4f58f75f1266 93 Gene3D G3DSA:3.30.1190.10 53 93 2.2E-6 T 29-03-2018 THSYN_RS23355 91a898d886885c7b71015a77ea031b8b 141 Gene3D G3DSA:1.20.1440.60 1 115 8.3E-13 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS23355 91a898d886885c7b71015a77ea031b8b 141 SUPERFAMILY SSF158446 3 114 1.96E-6 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS23355 91a898d886885c7b71015a77ea031b8b 141 Pfam PF05635 23S rRNA-intervening sequence protein 5 87 1.3E-6 T 29-03-2018 IPR012657 23S rRNA-intervening sequence protein THSYN_RS20660 a35cb086f0eaecfcfe104bbf09fc4e84 372 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 2 369 2.0E-139 T 29-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 THSYN_RS20660 a35cb086f0eaecfcfe104bbf09fc4e84 372 Pfam PF01924 Hydrogenase formation hypA family 12 366 2.3E-151 T 29-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 THSYN_RS20660 a35cb086f0eaecfcfe104bbf09fc4e84 372 PIRSF PIRSF005622 1 371 1.2E-153 T 29-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 THSYN_RS11940 be3ad760bb3cbb67364a24d876aa996b 247 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 27 236 1.1E-32 T 29-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 THSYN_RS25570 1915b2438cd0bcd76c9521c2f8f4a83a 212 Gene3D G3DSA:1.10.10.10 142 212 6.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25570 1915b2438cd0bcd76c9521c2f8f4a83a 212 SMART SM00421 146 203 1.3E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS25570 1915b2438cd0bcd76c9521c2f8f4a83a 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 1.3E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS25570 1915b2438cd0bcd76c9521c2f8f4a83a 212 SMART SM00448 3 116 8.4E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS25570 1915b2438cd0bcd76c9521c2f8f4a83a 212 SUPERFAMILY SSF46894 143 208 9.52E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS25570 1915b2438cd0bcd76c9521c2f8f4a83a 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS25570 1915b2438cd0bcd76c9521c2f8f4a83a 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 3.4E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS25570 1915b2438cd0bcd76c9521c2f8f4a83a 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 3.4E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS25570 1915b2438cd0bcd76c9521c2f8f4a83a 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 3.4E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS25570 1915b2438cd0bcd76c9521c2f8f4a83a 212 SUPERFAMILY SSF52172 2 129 3.42E-31 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS25570 1915b2438cd0bcd76c9521c2f8f4a83a 212 Gene3D G3DSA:3.40.50.2300 2 141 8.4E-36 T 29-03-2018 THSYN_RS25570 1915b2438cd0bcd76c9521c2f8f4a83a 212 Pfam PF00072 Response regulator receiver domain 6 117 5.6E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS09475 6a34b9623eb9532da7a7a0297f7e8fbc 183 Gene3D G3DSA:3.40.50.2020 3 183 4.0E-39 T 29-03-2018 THSYN_RS09475 6a34b9623eb9532da7a7a0297f7e8fbc 183 Pfam PF00156 Phosphoribosyl transferase domain 20 139 6.1E-21 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THSYN_RS09475 6a34b9623eb9532da7a7a0297f7e8fbc 183 SUPERFAMILY SSF53271 12 179 1.57E-41 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like THSYN_RS16490 28760ebee4df24b1b23fb87046371bdf 136 Pfam PF11042 Protein of unknown function (DUF2750) 13 115 1.4E-33 T 29-03-2018 IPR021284 Protein of unknown function DUF2750 THSYN_RS23190 a6895422738fcb2ed59e4db0d483a7df 320 Pfam PF01040 UbiA prenyltransferase family 49 291 2.9E-34 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 THSYN_RS23190 a6895422738fcb2ed59e4db0d483a7df 320 PIRSF PIRSF005355 24 318 1.3E-78 T 29-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 THSYN_RS23190 a6895422738fcb2ed59e4db0d483a7df 320 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 39 312 4.8E-54 T 29-03-2018 THSYN_RS23190 a6895422738fcb2ed59e4db0d483a7df 320 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 30 314 20.126 T 29-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 THSYN_RS31440 feac94a1c58cd6d00ce53f73cdf8ee2f 161 Pfam PF01724 Domain of unknown function DUF29 7 152 1.5E-46 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS21915 95d5cb3f493c89767e659b9aeb056985 178 SUPERFAMILY SSF102114 5 72 1.57E-7 T 29-03-2018 THSYN_RS21915 95d5cb3f493c89767e659b9aeb056985 178 Gene3D G3DSA:3.80.30.20 1 85 1.2E-7 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe THSYN_RS02470 385f94ed072395085906dd8892c52bc8 374 Pfam PF13439 Glycosyltransferase Family 4 23 177 1.7E-11 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS02470 385f94ed072395085906dd8892c52bc8 374 SUPERFAMILY SSF53756 19 357 1.06E-59 T 29-03-2018 THSYN_RS02470 385f94ed072395085906dd8892c52bc8 374 Gene3D G3DSA:3.40.50.2000 6 188 4.0E-9 T 29-03-2018 THSYN_RS02470 385f94ed072395085906dd8892c52bc8 374 Pfam PF00534 Glycosyl transferases group 1 193 342 3.3E-30 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS02470 385f94ed072395085906dd8892c52bc8 374 Gene3D G3DSA:3.40.50.2000 189 355 2.3E-36 T 29-03-2018 THSYN_RS11285 2045a9cde7d7c53232d5643d8b7f2e7c 276 Gene3D G3DSA:3.40.190.80 154 266 2.6E-16 T 29-03-2018 THSYN_RS11285 2045a9cde7d7c53232d5643d8b7f2e7c 276 Pfam PF00459 Inositol monophosphatase family 13 224 4.3E-41 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS11285 2045a9cde7d7c53232d5643d8b7f2e7c 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 36 56 1.9E-19 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS11285 2045a9cde7d7c53232d5643d8b7f2e7c 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 176 197 1.9E-19 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS11285 2045a9cde7d7c53232d5643d8b7f2e7c 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 1.9E-19 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS11285 2045a9cde7d7c53232d5643d8b7f2e7c 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 58 74 1.9E-19 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS11285 2045a9cde7d7c53232d5643d8b7f2e7c 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 1.9E-19 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS11285 2045a9cde7d7c53232d5643d8b7f2e7c 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 1.9E-19 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THSYN_RS11285 2045a9cde7d7c53232d5643d8b7f2e7c 276 SUPERFAMILY SSF56655 7 263 1.57E-57 T 29-03-2018 THSYN_RS11285 2045a9cde7d7c53232d5643d8b7f2e7c 276 Gene3D G3DSA:3.30.540.10 3 153 1.7E-34 T 29-03-2018 THSYN_RS17775 9c168699dbedd4e43e927d1bec04b5a7 726 SUPERFAMILY SSF48452 355 484 5.14E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS17775 9c168699dbedd4e43e927d1bec04b5a7 726 Gene3D G3DSA:1.25.40.10 294 408 9.4E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS17775 9c168699dbedd4e43e927d1bec04b5a7 726 Pfam PF14559 Tetratricopeptide repeat 407 466 2.3E-7 T 29-03-2018 THSYN_RS17775 9c168699dbedd4e43e927d1bec04b5a7 726 Gene3D G3DSA:1.25.40.10 409 514 4.0E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS20770 1e8ff1b0610a0d0b70024aa2c133c324 109 Gene3D G3DSA:3.30.460.10 1 109 1.2E-14 T 29-03-2018 THSYN_RS20770 1e8ff1b0610a0d0b70024aa2c133c324 109 SUPERFAMILY SSF81301 10 109 1.4E-12 T 29-03-2018 THSYN_RS20770 1e8ff1b0610a0d0b70024aa2c133c324 109 Pfam PF01909 Nucleotidyltransferase domain 12 51 1.3E-4 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS28005 f8753b668a3360818ce642529d726f49 77 Pfam PF02599 Global regulator protein family 1 52 3.0E-26 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 THSYN_RS28005 f8753b668a3360818ce642529d726f49 77 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 49 6.0E-20 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 THSYN_RS28005 f8753b668a3360818ce642529d726f49 77 SUPERFAMILY SSF117130 1 54 1.96E-20 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 THSYN_RS28005 f8753b668a3360818ce642529d726f49 77 Hamap MF_00167 Carbon storage regulator [csrA]. 1 72 21.538 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 THSYN_RS28005 f8753b668a3360818ce642529d726f49 77 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 58 9.1E-29 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 THSYN_RS28055 3a83ab5589db84e8d9677753b0a44989 161 Gene3D G3DSA:3.40.50.1010 8 146 3.2E-14 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS28055 3a83ab5589db84e8d9677753b0a44989 161 SUPERFAMILY SSF88723 9 142 3.6E-14 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS28055 3a83ab5589db84e8d9677753b0a44989 161 Pfam PF01850 PIN domain 10 137 9.0E-10 T 29-03-2018 IPR002716 PIN domain THSYN_RS28055 3a83ab5589db84e8d9677753b0a44989 161 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 10 149 9.54 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 SUPERFAMILY SSF55816 413 605 5.62E-35 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 SUPERFAMILY SSF56300 37 381 3.8E-36 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 Gene3D G3DSA:3.60.21.10 32 416 8.8E-42 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 Gene3D G3DSA:3.90.780.10 417 626 3.3E-41 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 701 771 7.5E-5 T 29-03-2018 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 PRINTS PR01607 Apyrase family signature 326 346 3.2E-14 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 PRINTS PR01607 Apyrase family signature 465 488 3.2E-14 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 PRINTS PR01607 Apyrase family signature 276 299 3.2E-14 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 PRINTS PR01607 Apyrase family signature 556 575 3.2E-14 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 PRINTS PR01607 Apyrase family signature 37 55 3.2E-14 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 PRINTS PR01607 Apyrase family signature 255 272 3.2E-14 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 SUPERFAMILY SSF51120 628 729 2.88E-15 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 SUPERFAMILY SSF51120 586 595 2.88E-15 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal THSYN_RS19830 1f12352480e0909c84ce58387e8b062e 781 Pfam PF02872 5'-nucleotidase, C-terminal domain 425 580 6.2E-32 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THSYN_RS20530 987624d271d76f134bbbf19c77ddebea 129 Gene3D G3DSA:3.30.870.10 2 117 2.5E-14 T 29-03-2018 THSYN_RS20530 987624d271d76f134bbbf19c77ddebea 129 SUPERFAMILY SSF56024 4 75 7.4E-12 T 29-03-2018 THSYN_RS20530 987624d271d76f134bbbf19c77ddebea 129 Pfam PF13091 PLD-like domain 4 72 6.9E-12 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THSYN_RS09045 6dd66f6bb61ed62a1e2659223cdac7e7 178 SUPERFAMILY SSF158710 21 163 1.7E-35 T 29-03-2018 IPR023153 PSPTO4464-like domain THSYN_RS09045 6dd66f6bb61ed62a1e2659223cdac7e7 178 Gene3D G3DSA:1.10.60.30 22 91 2.2E-11 T 29-03-2018 THSYN_RS09045 6dd66f6bb61ed62a1e2659223cdac7e7 178 Gene3D G3DSA:1.10.60.30 96 169 6.7E-24 T 29-03-2018 THSYN_RS09045 6dd66f6bb61ed62a1e2659223cdac7e7 178 Pfam PF04751 Protein of unknown function (DUF615) 10 160 3.6E-41 T 29-03-2018 IPR006839 Ribosome-associated, YjgA THSYN_RS09045 6dd66f6bb61ed62a1e2659223cdac7e7 178 PIRSF PIRSF016183 1 168 6.9E-42 T 29-03-2018 IPR006839 Ribosome-associated, YjgA THSYN_RS07305 f7611e8702b8297e16b63fe3de290540 135 Pfam PF14229 Domain of unknown function (DUF4332) 11 129 2.2E-33 T 29-03-2018 IPR025567 Domain of unknown function DUF4332 KEGG: 00970+6.1.1.6 THSYN_RS07305 f7611e8702b8297e16b63fe3de290540 135 Gene3D G3DSA:1.10.150.20 70 130 7.2E-9 T 29-03-2018 THSYN_RS13475 d0b206fc6d4ca9166b8721d7b3be2e15 234 SUPERFAMILY SSF52540 52 223 2.43E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13475 d0b206fc6d4ca9166b8721d7b3be2e15 234 Gene3D G3DSA:3.40.50.300 1 226 7.0E-18 T 29-03-2018 THSYN_RS28660 5c9edbed6b6f4ed9e9b3bbbf974fabad 414 Gene3D G3DSA:4.10.320.10 112 167 2.9E-14 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 THSYN_RS28660 5c9edbed6b6f4ed9e9b3bbbf974fabad 414 SUPERFAMILY SSF47005 112 153 2.88E-10 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 THSYN_RS28660 5c9edbed6b6f4ed9e9b3bbbf974fabad 414 Gene3D G3DSA:3.90.1170.30 1 47 1.4E-10 T 29-03-2018 THSYN_RS28660 5c9edbed6b6f4ed9e9b3bbbf974fabad 414 Gene3D G3DSA:2.40.50.100 48 111 0.11 T 29-03-2018 THSYN_RS28660 5c9edbed6b6f4ed9e9b3bbbf974fabad 414 SUPERFAMILY SSF52777 184 412 1.6E-86 T 29-03-2018 THSYN_RS28660 5c9edbed6b6f4ed9e9b3bbbf974fabad 414 SUPERFAMILY SSF51230 2 94 1.83E-23 T 29-03-2018 IPR011053 Single hybrid motif THSYN_RS28660 5c9edbed6b6f4ed9e9b3bbbf974fabad 414 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 413 6.5E-168 T 29-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 THSYN_RS28660 5c9edbed6b6f4ed9e9b3bbbf974fabad 414 Pfam PF00364 Biotin-requiring enzyme 4 76 1.1E-16 T 29-03-2018 IPR000089 Biotin/lipoyl attachment THSYN_RS28660 5c9edbed6b6f4ed9e9b3bbbf974fabad 414 Gene3D G3DSA:3.30.559.10 172 412 1.1E-86 T 29-03-2018 THSYN_RS28660 5c9edbed6b6f4ed9e9b3bbbf974fabad 414 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 184 412 1.4E-80 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 THSYN_RS28660 5c9edbed6b6f4ed9e9b3bbbf974fabad 414 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 THSYN_RS28660 5c9edbed6b6f4ed9e9b3bbbf974fabad 414 Pfam PF02817 e3 binding domain 116 148 2.4E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 THSYN_RS05295 3af11500b356d0998b36b53d85003ce9 312 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 20 304 2.8E-80 T 29-03-2018 THSYN_RS05295 3af11500b356d0998b36b53d85003ce9 312 PIRSF PIRSF015582 3 309 3.0E-46 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like THSYN_RS05295 3af11500b356d0998b36b53d85003ce9 312 SUPERFAMILY SSF51621 21 255 3.3E-29 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THSYN_RS05295 3af11500b356d0998b36b53d85003ce9 312 Gene3D G3DSA:3.20.20.360 7 278 3.9E-32 T 29-03-2018 THSYN_RS02190 dec8251a3ed98744acac5fe9f89e131c 262 Pfam PF05050 Methyltransferase FkbM domain 61 220 2.6E-18 T 29-03-2018 IPR006342 Methyltransferase FkbM THSYN_RS02190 dec8251a3ed98744acac5fe9f89e131c 262 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 59 195 7.4E-31 T 29-03-2018 IPR006342 Methyltransferase FkbM THSYN_RS02190 dec8251a3ed98744acac5fe9f89e131c 262 Gene3D G3DSA:3.40.50.150 46 237 1.1E-35 T 29-03-2018 THSYN_RS02190 dec8251a3ed98744acac5fe9f89e131c 262 SUPERFAMILY SSF53335 25 225 3.84E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS23905 84948348947fa7b7efa717b5b99b42e7 101 SUPERFAMILY SSF54189 9 97 1.51E-26 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23905 84948348947fa7b7efa717b5b99b42e7 101 Pfam PF00276 Ribosomal protein L23 12 97 1.5E-26 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 THSYN_RS23905 84948348947fa7b7efa717b5b99b42e7 101 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 11 100 20.628 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 THSYN_RS23905 84948348947fa7b7efa717b5b99b42e7 101 Gene3D G3DSA:3.30.70.330 9 100 3.9E-26 T 29-03-2018 THSYN_RS19455 b55abd9d33147bec1425e087c232a94b 374 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 344 1.7E-61 T 29-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 THSYN_RS19455 b55abd9d33147bec1425e087c232a94b 374 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 4 347 3.4E-89 T 29-03-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 THSYN_RS22120 edb3eb113de6d6a90a47c15f6220db30 151 Gene3D G3DSA:2.60.260.20 1 70 4.9E-19 T 29-03-2018 THSYN_RS22120 edb3eb113de6d6a90a47c15f6220db30 151 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 138 21.533 T 29-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 THSYN_RS22120 edb3eb113de6d6a90a47c15f6220db30 151 PIRSF PIRSF036402 1 149 1.5E-42 T 29-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 THSYN_RS22120 edb3eb113de6d6a90a47c15f6220db30 151 Pfam PF02814 UreE urease accessory protein, N-terminal domain 14 62 6.5E-17 T 29-03-2018 IPR004029 UreE urease accessory, N-terminal THSYN_RS22120 edb3eb113de6d6a90a47c15f6220db30 151 SMART SM00988 1 64 1.9E-21 T 29-03-2018 IPR004029 UreE urease accessory, N-terminal THSYN_RS22120 edb3eb113de6d6a90a47c15f6220db30 151 Pfam PF05194 UreE urease accessory protein, C-terminal domain 71 147 8.8E-24 T 29-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 THSYN_RS22120 edb3eb113de6d6a90a47c15f6220db30 151 Gene3D G3DSA:3.30.70.790 71 151 1.9E-28 T 29-03-2018 THSYN_RS22120 edb3eb113de6d6a90a47c15f6220db30 151 SUPERFAMILY SSF69287 1 68 1.44E-17 T 29-03-2018 IPR004029 UreE urease accessory, N-terminal THSYN_RS22120 edb3eb113de6d6a90a47c15f6220db30 151 SUPERFAMILY SSF69737 70 137 1.96E-18 T 29-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 THSYN_RS29235 e6d0049e14d214abdd5da9933dfce571 173 Pfam PF13673 Acetyltransferase (GNAT) domain 101 164 6.4E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS29235 e6d0049e14d214abdd5da9933dfce571 173 Gene3D G3DSA:3.40.630.30 3 171 6.7E-14 T 29-03-2018 THSYN_RS29235 e6d0049e14d214abdd5da9933dfce571 173 SUPERFAMILY SSF55729 15 165 8.15E-13 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS10800 762165437df17e19a1e8362d7d66f8b5 383 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 15 31 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS10800 762165437df17e19a1e8362d7d66f8b5 383 TIGRFAM TIGR02660 nifV_homocitr: homocitrate synthase 8 370 2.6E-157 T 29-03-2018 IPR013477 Homocitrate synthase NifV-type GO:0004410|GO:0051188 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 THSYN_RS10800 762165437df17e19a1e8362d7d66f8b5 383 Pfam PF00682 HMGL-like 8 265 2.6E-80 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 THSYN_RS10800 762165437df17e19a1e8362d7d66f8b5 383 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 194 207 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THSYN_RS10800 762165437df17e19a1e8362d7d66f8b5 383 Gene3D G3DSA:3.20.20.70 1 333 1.1E-93 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS10800 762165437df17e19a1e8362d7d66f8b5 383 SUPERFAMILY SSF51569 8 282 1.74E-81 T 29-03-2018 THSYN_RS07235 0449c2b6b7790bfd57756c0b0a0af213 323 Pfam PF00535 Glycosyl transferase family 2 7 125 7.7E-21 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS07235 0449c2b6b7790bfd57756c0b0a0af213 323 Gene3D G3DSA:3.90.550.10 1 234 3.6E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS07235 0449c2b6b7790bfd57756c0b0a0af213 323 SUPERFAMILY SSF53448 3 256 6.75E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS06525 67b0de821dcfc2f6875a999cdf05970f 237 Gene3D G3DSA:1.10.530.10 52 236 1.9E-44 T 29-03-2018 THSYN_RS06525 67b0de821dcfc2f6875a999cdf05970f 237 Pfam PF01464 Transglycosylase SLT domain 113 212 3.4E-26 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 THSYN_RS06525 67b0de821dcfc2f6875a999cdf05970f 237 Pfam PF13511 Domain of unknown function (DUF4124) 11 89 3.0E-9 T 29-03-2018 IPR025392 Domain of unknown function DUF4124 THSYN_RS06525 67b0de821dcfc2f6875a999cdf05970f 237 SUPERFAMILY SSF53955 91 235 2.81E-44 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS22890 c55705314c67d3d50c8ab4c7b2e58ef1 124 Gene3D G3DSA:1.10.10.10 13 105 4.1E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS22890 c55705314c67d3d50c8ab4c7b2e58ef1 124 SUPERFAMILY SSF46785 50 101 5.36E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS01275 a868dedc570042efbb5eee2a7dd730eb 106 PIRSF PIRSF039032 1 105 6.4E-35 T 29-03-2018 IPR009387 Toxin HigB-2 THSYN_RS32150 007b6f166ccde11f591723ed9b85cb34 250 Pfam PF02361 Cobalt transport protein 11 214 1.7E-38 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component THSYN_RS32150 007b6f166ccde11f591723ed9b85cb34 250 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 17 208 5.9E-43 T 29-03-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 THSYN_RS16420 2e880de5272280c8bb80e53156c42a12 94 Gene3D G3DSA:1.10.260.40 9 94 1.2E-5 T 29-03-2018 THSYN_RS16420 2e880de5272280c8bb80e53156c42a12 94 SUPERFAMILY SSF47413 53 94 3.49E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS16420 2e880de5272280c8bb80e53156c42a12 94 Pfam PF13744 Helix-turn-helix domain 55 94 2.9E-8 T 29-03-2018 THSYN_RS14730 d206c71821faf73906495a6fd7f191e9 1000 Gene3D G3DSA:3.40.50.300 247 565 4.6E-6 T 29-03-2018 THSYN_RS14730 d206c71821faf73906495a6fd7f191e9 1000 SUPERFAMILY SSF56436 737 999 1.15E-65 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS14730 d206c71821faf73906495a6fd7f191e9 1000 SUPERFAMILY SSF52540 256 481 3.66E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14730 d206c71821faf73906495a6fd7f191e9 1000 Gene3D G3DSA:3.90.1580.10 735 797 1.3E-12 T 29-03-2018 THSYN_RS14730 d206c71821faf73906495a6fd7f191e9 1000 Gene3D G3DSA:3.90.1580.10 798 1000 3.2E-49 T 29-03-2018 THSYN_RS14730 d206c71821faf73906495a6fd7f191e9 1000 Pfam PF03781 Sulfatase-modifying factor enzyme 1 737 998 1.7E-57 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS19945 3abb973779b659092aa0f7f5955a91c0 379 SUPERFAMILY SSF52540 6 124 4.14E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19945 3abb973779b659092aa0f7f5955a91c0 379 SUPERFAMILY SSF52540 204 338 4.14E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19945 3abb973779b659092aa0f7f5955a91c0 379 Gene3D G3DSA:3.40.50.300 1 342 7.8E-20 T 29-03-2018 THSYN_RS19945 3abb973779b659092aa0f7f5955a91c0 379 SMART SM00382 21 337 6.5E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS19945 3abb973779b659092aa0f7f5955a91c0 379 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 26 123 7.8E-9 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS19945 3abb973779b659092aa0f7f5955a91c0 379 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 251 322 4.4E-14 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS22785 a10d33d0b5964b07f1114cb3d1779a9d 349 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 250 2.5E-54 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THSYN_RS22785 a10d33d0b5964b07f1114cb3d1779a9d 349 Gene3D G3DSA:3.90.25.10 173 335 7.5E-33 T 29-03-2018 THSYN_RS22785 a10d33d0b5964b07f1114cb3d1779a9d 349 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 6 332 2.0E-118 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 THSYN_RS22785 a10d33d0b5964b07f1114cb3d1779a9d 349 SUPERFAMILY SSF51735 3 331 2.71E-86 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS22785 a10d33d0b5964b07f1114cb3d1779a9d 349 Gene3D G3DSA:3.40.50.720 3 172 1.3E-34 T 29-03-2018 THSYN_RS25140 5b35a19390e2e93f7d106776d6a7b9eb 138 Gene3D G3DSA:2.60.120.10 4 138 5.7E-31 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS25140 5b35a19390e2e93f7d106776d6a7b9eb 138 SUPERFAMILY SSF51182 8 133 1.71E-43 T 29-03-2018 IPR011051 RmlC-like cupin domain THSYN_RS25140 5b35a19390e2e93f7d106776d6a7b9eb 138 Pfam PF05523 WxcM-like, C-terminal 7 134 3.8E-58 T 29-03-2018 IPR008894 WxcM-like, C-terminal KEGG: 00523+5.3.2.3|MetaCyc: PWY-6953|MetaCyc: PWY-7688 THSYN_RS14085 39c909146eb821723fbdaef179549ff9 201 PIRSF PIRSF015617 5 201 7.2E-70 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 THSYN_RS14085 39c909146eb821723fbdaef179549ff9 201 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 31 200 2.1E-66 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 THSYN_RS14085 39c909146eb821723fbdaef179549ff9 201 Pfam PF12557 Cob(I)alamin adenosyltransferase N terminal 1 25 6.4E-6 T 29-03-2018 IPR025826 Cob(I)alamin adenosyltransferase N-terminal domain KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 THSYN_RS14085 39c909146eb821723fbdaef179549ff9 201 Gene3D G3DSA:3.40.50.300 10 201 5.8E-72 T 29-03-2018 THSYN_RS14085 39c909146eb821723fbdaef179549ff9 201 SUPERFAMILY SSF52540 11 200 5.63E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14085 39c909146eb821723fbdaef179549ff9 201 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 32 200 9.3E-61 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 THSYN_RS21720 6500b2a003e735ca06f2c26888e7c3ac 367 Pfam PF01264 Chorismate synthase 10 345 5.3E-134 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THSYN_RS21720 6500b2a003e735ca06f2c26888e7c3ac 367 Gene3D G3DSA:3.60.150.10 3 356 1.6E-152 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THSYN_RS21720 6500b2a003e735ca06f2c26888e7c3ac 367 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THSYN_RS21720 6500b2a003e735ca06f2c26888e7c3ac 367 PIRSF PIRSF001456 3 362 1.0E-134 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THSYN_RS21720 6500b2a003e735ca06f2c26888e7c3ac 367 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THSYN_RS21720 6500b2a003e735ca06f2c26888e7c3ac 367 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THSYN_RS21720 6500b2a003e735ca06f2c26888e7c3ac 367 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 36.447 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THSYN_RS21720 6500b2a003e735ca06f2c26888e7c3ac 367 SUPERFAMILY SSF103263 4 351 3.4E-142 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THSYN_RS21720 6500b2a003e735ca06f2c26888e7c3ac 367 TIGRFAM TIGR00033 aroC: chorismate synthase 11 350 1.7E-132 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THSYN_RS20585 6227b496442de3943652e5c5c055f8a1 158 Hamap MF_00598 Protein Smg [smg]. 5 158 28.539 T 29-03-2018 IPR007456 Smg THSYN_RS20585 6227b496442de3943652e5c5c055f8a1 158 Pfam PF04361 Protein of unknown function (DUF494) 5 158 1.9E-52 T 29-03-2018 IPR007456 Smg THSYN_RS27625 69e20250126abc0f3d294aa61edc1a6b 359 Pfam PF03462 PCRF domain 13 203 1.3E-68 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 THSYN_RS27625 69e20250126abc0f3d294aa61edc1a6b 359 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 354 1.7E-154 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 THSYN_RS27625 69e20250126abc0f3d294aa61edc1a6b 359 Gene3D G3DSA:1.20.58.410 2 103 1.9E-15 T 29-03-2018 THSYN_RS27625 69e20250126abc0f3d294aa61edc1a6b 359 SUPERFAMILY SSF75620 12 353 3.27E-129 T 29-03-2018 THSYN_RS27625 69e20250126abc0f3d294aa61edc1a6b 359 Pfam PF00472 RF-1 domain 212 321 3.3E-40 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THSYN_RS27625 69e20250126abc0f3d294aa61edc1a6b 359 SMART SM00937 63 178 3.2E-55 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 THSYN_RS27625 69e20250126abc0f3d294aa61edc1a6b 359 Gene3D G3DSA:3.30.160.20 209 291 1.1E-31 T 29-03-2018 THSYN_RS27625 69e20250126abc0f3d294aa61edc1a6b 359 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THSYN_RS27625 69e20250126abc0f3d294aa61edc1a6b 359 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 39.196 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 THSYN_RS27205 4ba87bb3027333585b11667c1efa5fd3 108 SUPERFAMILY SSF56436 74 103 6.36E-7 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS27205 4ba87bb3027333585b11667c1efa5fd3 108 SUPERFAMILY SSF56436 1 18 6.36E-7 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS27205 4ba87bb3027333585b11667c1efa5fd3 108 Gene3D G3DSA:3.90.1580.10 1 108 4.5E-6 T 29-03-2018 THSYN_RS01580 53ca7829089e4999a8a9c367dd0798c3 146 SUPERFAMILY SSF88723 9 127 1.41E-12 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS01580 53ca7829089e4999a8a9c367dd0798c3 146 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 9 124 1.6E-17 T 29-03-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component THSYN_RS01580 53ca7829089e4999a8a9c367dd0798c3 146 Pfam PF13470 PIN domain 9 118 2.9E-22 T 29-03-2018 IPR002716 PIN domain THSYN_RS01580 53ca7829089e4999a8a9c367dd0798c3 146 Gene3D G3DSA:3.40.50.1010 8 137 9.6E-11 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS09790 725393460aabc77840215a85d733858f 217 SUPERFAMILY SSF49384 29 180 2.09E-6 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 THSYN_RS09790 725393460aabc77840215a85d733858f 217 Gene3D G3DSA:2.60.40.680 17 184 1.8E-14 T 29-03-2018 THSYN_RS09790 725393460aabc77840215a85d733858f 217 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 182 204 0.0021 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS18575 77b31d7946f2710d5868b7c428ee943b 193 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 48 70 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THSYN_RS18575 77b31d7946f2710d5868b7c428ee943b 193 Pfam PF01066 CDP-alcohol phosphatidyltransferase 3 70 2.7E-15 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THSYN_RS18575 77b31d7946f2710d5868b7c428ee943b 193 PIRSF PIRSF000847 1 189 4.2E-45 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 THSYN_RS18575 77b31d7946f2710d5868b7c428ee943b 193 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 3 180 2.2E-53 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 THSYN_RS11500 88d3ab73edd53f7cd5a8fc05ce510392 444 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 5 444 2.6E-147 T 29-03-2018 IPR010263 Type VI secretion protein, VC_A0114 THSYN_RS11500 88d3ab73edd53f7cd5a8fc05ce510392 444 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 19 442 5.9E-150 T 29-03-2018 IPR010263 Type VI secretion protein, VC_A0114 THSYN_RS21920 18568ad21e9c2eba5a8a17ed008cfe31 273 Gene3D G3DSA:3.20.20.450 1 254 3.3E-90 T 29-03-2018 IPR001633 EAL domain THSYN_RS21920 18568ad21e9c2eba5a8a17ed008cfe31 273 SUPERFAMILY SSF141868 2 251 5.49E-81 T 29-03-2018 IPR001633 EAL domain THSYN_RS21920 18568ad21e9c2eba5a8a17ed008cfe31 273 Pfam PF00563 EAL domain 2 237 1.4E-70 T 29-03-2018 IPR001633 EAL domain THSYN_RS21920 18568ad21e9c2eba5a8a17ed008cfe31 273 SMART SM00052 2 242 3.5E-94 T 29-03-2018 IPR001633 EAL domain THSYN_RS29415 68fec48a80e44be9135cf3d43c071159 321 Pfam PF13353 4Fe-4S single cluster domain 30 123 1.4E-4 T 29-03-2018 THSYN_RS29415 68fec48a80e44be9135cf3d43c071159 321 Gene3D G3DSA:3.20.20.70 17 242 6.4E-19 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS29415 68fec48a80e44be9135cf3d43c071159 321 SUPERFAMILY SSF102114 23 315 4.45E-39 T 29-03-2018 THSYN_RS29415 68fec48a80e44be9135cf3d43c071159 321 TIGRFAM TIGR04167 rSAM_SeCys: radical SAM/Cys-rich domain protein 16 319 1.8E-131 T 29-03-2018 IPR026351 Radical SAM/Cys-rich domain protein THSYN_RS29415 68fec48a80e44be9135cf3d43c071159 321 Pfam PF12345 Protein of unknown function (DUF3641) 182 318 1.0E-53 T 29-03-2018 IPR024521 Domain of unknown function DUF3641 THSYN_RS29415 68fec48a80e44be9135cf3d43c071159 321 Pfam PF04055 Radical SAM superfamily 30 166 1.2E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS21115 687db49496fdc5256182a9eb213a4bc4 817 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 376 542 1.7E-38 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS21115 687db49496fdc5256182a9eb213a4bc4 817 Pfam PF00990 Diguanylate cyclase, GGDEF domain 380 539 3.8E-42 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS21115 687db49496fdc5256182a9eb213a4bc4 817 SUPERFAMILY SSF158472 322 371 8.5E-8 T 29-03-2018 THSYN_RS21115 687db49496fdc5256182a9eb213a4bc4 817 SMART SM00052 554 800 7.2E-112 T 29-03-2018 IPR001633 EAL domain THSYN_RS21115 687db49496fdc5256182a9eb213a4bc4 817 Gene3D G3DSA:3.20.20.450 552 814 4.5E-101 T 29-03-2018 IPR001633 EAL domain THSYN_RS21115 687db49496fdc5256182a9eb213a4bc4 817 Pfam PF00672 HAMP domain 322 370 2.4E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS21115 687db49496fdc5256182a9eb213a4bc4 817 Pfam PF00563 EAL domain 560 795 1.0E-74 T 29-03-2018 IPR001633 EAL domain THSYN_RS21115 687db49496fdc5256182a9eb213a4bc4 817 SUPERFAMILY SSF141868 559 807 7.45E-87 T 29-03-2018 IPR001633 EAL domain THSYN_RS21115 687db49496fdc5256182a9eb213a4bc4 817 SMART SM00267 369 544 2.6E-55 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS21115 687db49496fdc5256182a9eb213a4bc4 817 SUPERFAMILY SSF55073 385 545 2.55E-45 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS21115 687db49496fdc5256182a9eb213a4bc4 817 Gene3D G3DSA:3.30.70.270 374 551 3.8E-58 T 29-03-2018 THSYN_RS21115 687db49496fdc5256182a9eb213a4bc4 817 SMART SM00304 322 374 7.3E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THSYN_RS05980 1bf54f8419210a273ee213e33e743350 201 Gene3D G3DSA:3.90.1570.10 10 197 1.9E-43 T 29-03-2018 THSYN_RS05980 1bf54f8419210a273ee213e33e743350 201 SUPERFAMILY SSF52980 13 197 4.24E-49 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS05980 1bf54f8419210a273ee213e33e743350 201 Pfam PF05685 Putative restriction endonuclease 25 193 3.5E-34 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS24065 932ead26a1ad3c4e5516d80d0ed63750 126 Pfam PF16137 Domain of unknown function (DUF4845) 32 117 1.4E-18 T 29-03-2018 IPR032314 Protein of unknown function DUF4845 THSYN_RS07695 a18a1ef23757f4e15ab29cc665b0d2e7 404 Pfam PF00990 Diguanylate cyclase, GGDEF domain 237 393 3.7E-46 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS07695 a18a1ef23757f4e15ab29cc665b0d2e7 404 SMART SM00267 224 397 5.0E-62 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS07695 a18a1ef23757f4e15ab29cc665b0d2e7 404 SUPERFAMILY SSF55073 240 396 1.8E-47 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS07695 a18a1ef23757f4e15ab29cc665b0d2e7 404 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 232 395 5.1E-50 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS07695 a18a1ef23757f4e15ab29cc665b0d2e7 404 Gene3D G3DSA:3.30.70.270 219 398 3.1E-55 T 29-03-2018 THSYN_RS29525 29b14fe0e7626bb829e2aa49236fef60 76 Pfam PF06412 Conjugal transfer protein TraD 4 58 2.3E-12 T 29-03-2018 IPR009444 Conjugal transfer, TraD, alpha-type GO:0000746 THSYN_RS27845 eb05ad0de58b266c141e0da22d5a93c7 221 SUPERFAMILY SSF49384 31 180 2.72E-6 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 THSYN_RS27845 eb05ad0de58b266c141e0da22d5a93c7 221 Gene3D G3DSA:2.60.40.680 18 185 3.6E-15 T 29-03-2018 THSYN_RS14235 1296d5631b6f79a017fc66c805884f3a 108 Gene3D G3DSA:3.30.750.24 1 107 3.4E-8 T 29-03-2018 IPR002645 STAS domain THSYN_RS14235 1296d5631b6f79a017fc66c805884f3a 108 SUPERFAMILY SSF52091 1 105 1.94E-10 T 29-03-2018 IPR002645 STAS domain THSYN_RS08495 28ee21aea2f1e8f881de64191cbd8f93 123 Gene3D G3DSA:3.40.1230.10 1 123 5.8E-35 T 29-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein THSYN_RS08495 28ee21aea2f1e8f881de64191cbd8f93 123 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 14 121 1.1E-31 T 29-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein THSYN_RS08495 28ee21aea2f1e8f881de64191cbd8f93 123 SUPERFAMILY SSF64076 1 122 1.96E-37 T 29-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein THSYN_RS12535 c2c43f39f4c9e2f999cc807cc8805b69 185 Pfam PF01025 GrpE 30 172 3.2E-8 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THSYN_RS12535 c2c43f39f4c9e2f999cc807cc8805b69 185 Gene3D G3DSA:1.20.1170.10 10 133 3.0E-4 T 29-03-2018 THSYN_RS12535 c2c43f39f4c9e2f999cc807cc8805b69 185 Gene3D G3DSA:2.30.22.10 134 181 9.8E-6 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 THSYN_RS13970 68fa4b84faf86b99413c9d71ff72f8fe 210 PIRSF PIRSF009320 1 208 7.3E-29 T 29-03-2018 THSYN_RS13970 68fa4b84faf86b99413c9d71ff72f8fe 210 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 181 9.8E-14 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THSYN_RS13970 68fa4b84faf86b99413c9d71ff72f8fe 210 Gene3D G3DSA:3.40.50.300 1 69 4.4E-13 T 29-03-2018 THSYN_RS13970 68fa4b84faf86b99413c9d71ff72f8fe 210 Gene3D G3DSA:3.40.50.300 70 209 1.3E-13 T 29-03-2018 THSYN_RS13970 68fa4b84faf86b99413c9d71ff72f8fe 210 SUPERFAMILY SSF52540 2 206 6.94E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21585 72e6654676c248256c1d7ddc8fc9dd99 157 TIGRFAM TIGR02935 TIGR02935: probable nitrogen fixation protein 17 155 3.4E-58 T 29-03-2018 IPR004952 Uncharacterised protein family UPF0460 THSYN_RS21585 72e6654676c248256c1d7ddc8fc9dd99 157 Pfam PF03270 Protein of unknown function, DUF269 36 155 1.1E-50 T 29-03-2018 IPR004952 Uncharacterised protein family UPF0460 THSYN_RS21585 72e6654676c248256c1d7ddc8fc9dd99 157 PIRSF PIRSF005788 1 157 9.0E-64 T 29-03-2018 IPR004952 Uncharacterised protein family UPF0460 THSYN_RS33210 2d384bfc18901170f39018718e9d58f0 188 Gene3D G3DSA:1.20.58.290 118 180 1.9E-26 T 29-03-2018 THSYN_RS33210 2d384bfc18901170f39018718e9d58f0 188 SUPERFAMILY SSF50475 1 177 5.5E-51 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 THSYN_RS33210 2d384bfc18901170f39018718e9d58f0 188 Pfam PF04289 Protein of unknown function (DUF447) 4 175 7.4E-45 T 29-03-2018 IPR007386 Protein of unknown function DUF447 THSYN_RS33210 2d384bfc18901170f39018718e9d58f0 188 Gene3D G3DSA:2.30.110.10 1 117 8.7E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 THSYN_RS30220 6bc31aaaa4147f9bee4467552d5bf56b 94 Gene3D G3DSA:1.20.5.780 2 85 1.6E-12 T 29-03-2018 THSYN_RS02915 d56815dc2cceecbde1111daded103c5e 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 THSYN_RS02915 d56815dc2cceecbde1111daded103c5e 96 SMART SM00883 2 94 4.9E-60 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS02915 d56815dc2cceecbde1111daded103c5e 96 PRINTS PR00297 10kDa chaperonin signature 3 18 7.8E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS02915 d56815dc2cceecbde1111daded103c5e 96 PRINTS PR00297 10kDa chaperonin signature 60 72 7.8E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS02915 d56815dc2cceecbde1111daded103c5e 96 PRINTS PR00297 10kDa chaperonin signature 81 94 7.8E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS02915 d56815dc2cceecbde1111daded103c5e 96 PRINTS PR00297 10kDa chaperonin signature 25 46 7.8E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS02915 d56815dc2cceecbde1111daded103c5e 96 SUPERFAMILY SSF50129 1 95 8.48E-36 T 29-03-2018 IPR011032 GroES-like THSYN_RS02915 d56815dc2cceecbde1111daded103c5e 96 Gene3D G3DSA:2.30.33.40 1 95 3.2E-38 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS02915 d56815dc2cceecbde1111daded103c5e 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 3.2E-35 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS02915 d56815dc2cceecbde1111daded103c5e 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 27.733 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THSYN_RS17300 b64ee3af7ee30cfb3117154fbfa86f08 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 54 1.1E-13 T 29-03-2018 THSYN_RS17300 b64ee3af7ee30cfb3117154fbfa86f08 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 62 2.6E-14 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS17300 b64ee3af7ee30cfb3117154fbfa86f08 83 Gene3D G3DSA:3.40.1620.10 1 38 2.9E-12 T 29-03-2018 THSYN_RS17300 b64ee3af7ee30cfb3117154fbfa86f08 83 SUPERFAMILY SSF143120 1 52 4.97E-11 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS31675 9c6ed23e4e5516eb2668883fc3178ae8 245 SUPERFAMILY SSF53335 8 201 2.84E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS31675 9c6ed23e4e5516eb2668883fc3178ae8 245 Pfam PF07109 Magnesium-protoporphyrin IX methyltransferase C-terminus 132 232 8.1E-35 T 29-03-2018 IPR010940 Magnesium-protoporphyrin IX methyltransferase, C-terminal GO:0015995|GO:0046406 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31675 9c6ed23e4e5516eb2668883fc3178ae8 245 Gene3D G3DSA:3.40.50.150 4 227 5.0E-28 T 29-03-2018 THSYN_RS31675 9c6ed23e4e5516eb2668883fc3178ae8 245 Pfam PF03602 Conserved hypothetical protein 95 40 95 1.8E-6 T 29-03-2018 THSYN_RS31675 9c6ed23e4e5516eb2668883fc3178ae8 245 TIGRFAM TIGR02021 BchM-ChlM: magnesium protoporphyrin O-methyltransferase 10 230 7.1E-75 T 29-03-2018 IPR010251 Magnesium-protoporphyrin IX methyltransferase GO:0015995|GO:0046406 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS20065 ccff2a0592a8117175b6616bb5917a31 84 Pfam PF00462 Glutaredoxin 4 63 6.1E-21 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 THSYN_RS20065 ccff2a0592a8117175b6616bb5917a31 84 PRINTS PR00160 Glutaredoxin signature 46 59 1.1E-13 T 29-03-2018 IPR014025 Glutaredoxin subgroup THSYN_RS20065 ccff2a0592a8117175b6616bb5917a31 84 PRINTS PR00160 Glutaredoxin signature 60 73 1.1E-13 T 29-03-2018 IPR014025 Glutaredoxin subgroup THSYN_RS20065 ccff2a0592a8117175b6616bb5917a31 84 PRINTS PR00160 Glutaredoxin signature 4 22 1.1E-13 T 29-03-2018 IPR014025 Glutaredoxin subgroup THSYN_RS20065 ccff2a0592a8117175b6616bb5917a31 84 SUPERFAMILY SSF52833 1 83 5.95E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS20065 ccff2a0592a8117175b6616bb5917a31 84 Gene3D G3DSA:3.40.30.10 2 84 2.5E-26 T 29-03-2018 THSYN_RS20065 ccff2a0592a8117175b6616bb5917a31 84 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 82 7.8E-32 T 29-03-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 THSYN_RS21140 f0d59ee9c025c20dd775c6b2669a5af3 322 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 20 309 4.6E-90 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 THSYN_RS21140 f0d59ee9c025c20dd775c6b2669a5af3 322 Gene3D G3DSA:2.40.30.30 183 322 1.8E-43 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 THSYN_RS21140 f0d59ee9c025c20dd775c6b2669a5af3 322 SUPERFAMILY SSF82114 177 314 3.27E-45 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 THSYN_RS21140 f0d59ee9c025c20dd775c6b2669a5af3 322 Pfam PF01687 Riboflavin kinase 187 309 8.5E-38 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 THSYN_RS21140 f0d59ee9c025c20dd775c6b2669a5af3 322 PIRSF PIRSF004491 1 317 8.5E-99 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 THSYN_RS21140 f0d59ee9c025c20dd775c6b2669a5af3 322 Pfam PF06574 FAD synthetase 13 170 2.6E-49 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 THSYN_RS21140 f0d59ee9c025c20dd775c6b2669a5af3 322 SMART SM00904 186 310 5.6E-61 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 THSYN_RS21140 f0d59ee9c025c20dd775c6b2669a5af3 322 Gene3D G3DSA:3.40.50.620 1 182 7.5E-49 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS21140 f0d59ee9c025c20dd775c6b2669a5af3 322 SUPERFAMILY SSF52374 16 178 1.21E-29 T 29-03-2018 THSYN_RS03755 c1f2975b2a18a15d3a71c7219e3ca6e7 174 SMART SM00989 111 173 3.9E-19 T 29-03-2018 IPR004096 4-vinyl reductase, 4VR THSYN_RS03755 c1f2975b2a18a15d3a71c7219e3ca6e7 174 Gene3D G3DSA:3.30.1380.20 3 174 5.8E-31 T 29-03-2018 THSYN_RS03755 c1f2975b2a18a15d3a71c7219e3ca6e7 174 SUPERFAMILY SSF111126 20 171 1.2E-29 T 29-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain THSYN_RS03755 c1f2975b2a18a15d3a71c7219e3ca6e7 174 Pfam PF02830 V4R domain 114 172 4.3E-15 T 29-03-2018 IPR004096 4-vinyl reductase, 4VR THSYN_RS21360 607e3542482fc031af981b61897699b6 319 SUPERFAMILY SSF52540 110 284 4.72E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21360 607e3542482fc031af981b61897699b6 319 TIGRFAM TIGR03018 pepcterm_TyrKin: exopolysaccharide/PEP-CTERM locus tyrosine autokinase 74 281 9.7E-79 T 29-03-2018 THSYN_RS21360 607e3542482fc031af981b61897699b6 319 Pfam PF13614 AAA domain 115 262 1.2E-9 T 29-03-2018 IPR025669 AAA domain THSYN_RS21360 607e3542482fc031af981b61897699b6 319 Gene3D G3DSA:3.40.50.300 89 288 4.6E-27 T 29-03-2018 THSYN_RS15865 5b1fd02023407640c23dadd9d6dfdee4 318 SMART SM01321 9 123 3.2E-36 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS15865 5b1fd02023407640c23dadd9d6dfdee4 318 Pfam PF01797 Transposase IS200 like 14 120 3.3E-12 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS15865 5b1fd02023407640c23dadd9d6dfdee4 318 SUPERFAMILY SSF143422 1 128 3.4E-24 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS15865 5b1fd02023407640c23dadd9d6dfdee4 318 Gene3D G3DSA:3.30.70.1290 8 130 2.9E-26 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS08345 af84486cbff20e3680430d587ddc37d4 648 Gene3D G3DSA:3.40.50.300 20 419 4.9E-29 T 29-03-2018 THSYN_RS08345 af84486cbff20e3680430d587ddc37d4 648 SMART SM00491 476 605 4.8E-44 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 THSYN_RS08345 af84486cbff20e3680430d587ddc37d4 648 Gene3D G3DSA:3.40.50.300 449 630 3.2E-10 T 29-03-2018 THSYN_RS08345 af84486cbff20e3680430d587ddc37d4 648 SUPERFAMILY SSF52540 456 601 9.94E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08345 af84486cbff20e3680430d587ddc37d4 648 SUPERFAMILY SSF52540 16 111 3.78E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08345 af84486cbff20e3680430d587ddc37d4 648 SUPERFAMILY SSF52540 187 246 3.78E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08345 af84486cbff20e3680430d587ddc37d4 648 SUPERFAMILY SSF52540 564 601 3.78E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS08345 af84486cbff20e3680430d587ddc37d4 648 Pfam PF13307 Helicase C-terminal domain 461 618 3.1E-34 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 THSYN_RS03400 5b45bcd57a8b4fa3834683846ced3656 238 Gene3D G3DSA:3.40.50.410 32 204 1.8E-4 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS03400 5b45bcd57a8b4fa3834683846ced3656 238 SUPERFAMILY SSF53300 36 200 1.82E-8 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS06210 2f379ab44fb5e75505dd58b3a5b6b24c 493 Gene3D G3DSA:3.90.20.10 24 173 9.3E-5 T 29-03-2018 THSYN_RS04930 0c3a52a3be62bc6cde10c443112953ac 373 SUPERFAMILY SSF53098 239 308 9.86E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS04930 0c3a52a3be62bc6cde10c443112953ac 373 Pfam PF13701 Transposase DDE domain group 1 6 371 1.9E-21 T 29-03-2018 IPR025668 Transposase DDE domain THSYN_RS04930 0c3a52a3be62bc6cde10c443112953ac 373 Gene3D G3DSA:3.90.350.10 36 286 3.0E-5 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS15175 1d5b5cad83f9eac7117adb2f2a91c04b 83 SMART SM00966 7 52 0.007 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS15175 1d5b5cad83f9eac7117adb2f2a91c04b 83 Gene3D G3DSA:2.10.260.10 1 83 2.6E-14 T 29-03-2018 THSYN_RS15175 1d5b5cad83f9eac7117adb2f2a91c04b 83 SUPERFAMILY SSF89447 3 71 2.09E-12 T 29-03-2018 THSYN_RS03265 2df7100b6b4793afa8145843b48abadf 233 Pfam PF00106 short chain dehydrogenase 5 177 5.7E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS03265 2df7100b6b4793afa8145843b48abadf 233 Gene3D G3DSA:3.40.50.720 3 226 1.4E-43 T 29-03-2018 THSYN_RS03265 2df7100b6b4793afa8145843b48abadf 233 SUPERFAMILY SSF51735 5 223 5.63E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS03265 2df7100b6b4793afa8145843b48abadf 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 8.5E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS03265 2df7100b6b4793afa8145843b48abadf 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.5E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS03265 2df7100b6b4793afa8145843b48abadf 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 8.5E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS03265 2df7100b6b4793afa8145843b48abadf 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 8.5E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS03265 2df7100b6b4793afa8145843b48abadf 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 8.5E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS23100 ee6e2015400e5138708b0e5570843011 380 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 20 370 1.8E-86 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THSYN_RS23100 ee6e2015400e5138708b0e5570843011 380 Gene3D G3DSA:3.90.1150.10 243 380 6.0E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS23100 ee6e2015400e5138708b0e5570843011 380 Gene3D G3DSA:3.40.640.10 1 242 2.7E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS23100 ee6e2015400e5138708b0e5570843011 380 TIGRFAM TIGR02379 ECA_wecE: TDP-4-keto-6-deoxy-D-glucose transaminase 3 370 1.5E-185 T 29-03-2018 IPR012749 dTDP-4-amino-4,6-dideoxygalactose transaminase WecE-like MetaCyc: PWY-7315 THSYN_RS23100 ee6e2015400e5138708b0e5570843011 380 PIRSF PIRSF000390 1 378 2.2E-102 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THSYN_RS23100 ee6e2015400e5138708b0e5570843011 380 SUPERFAMILY SSF53383 3 370 1.39E-93 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS31840 92848e06abf9f94af4b33a121748208d 270 TIGRFAM TIGR03122 one_C_dehyd_C: formylmethanofuran dehydrogenase subunit C 4 268 2.8E-75 T 29-03-2018 IPR017550 Formylmethanofuran dehydrogenase subunit C GO:0015948|GO:0018493|GO:0046914|GO:0055114 KEGG: 00680+1.2.99.5|MetaCyc: PWY-5209|MetaCyc: PWY-7784 THSYN_RS31840 92848e06abf9f94af4b33a121748208d 270 Pfam PF01493 GXGXG motif 80 206 2.5E-16 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THSYN_RS31840 92848e06abf9f94af4b33a121748208d 270 SUPERFAMILY SSF69336 15 211 1.96E-41 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THSYN_RS31840 92848e06abf9f94af4b33a121748208d 270 Gene3D G3DSA:2.160.20.60 61 137 2.3E-10 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THSYN_RS31840 92848e06abf9f94af4b33a121748208d 270 Gene3D G3DSA:2.160.20.60 138 220 1.6E-17 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THSYN_RS16200 ec017b6635f84833a979bdf133370b49 320 SUPERFAMILY SSF55048 129 198 5.49E-16 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 THSYN_RS16200 ec017b6635f84833a979bdf133370b49 320 Gene3D G3DSA:3.30.70.250 141 185 1.3E-19 T 29-03-2018 THSYN_RS16200 ec017b6635f84833a979bdf133370b49 320 SUPERFAMILY SSF52151 191 310 2.51E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS16200 ec017b6635f84833a979bdf133370b49 320 SUPERFAMILY SSF52151 5 123 2.51E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS16200 ec017b6635f84833a979bdf133370b49 320 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 8 303 5.9E-42 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain THSYN_RS16200 ec017b6635f84833a979bdf133370b49 320 PIRSF PIRSF000446 2 312 1.4E-101 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 THSYN_RS16200 ec017b6635f84833a979bdf133370b49 320 Gene3D G3DSA:3.40.366.10 4 140 4.9E-40 T 29-03-2018 THSYN_RS16200 ec017b6635f84833a979bdf133370b49 320 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 6 292 7.6E-100 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 THSYN_RS16200 ec017b6635f84833a979bdf133370b49 320 Gene3D G3DSA:3.40.366.10 186 313 3.9E-28 T 29-03-2018 THSYN_RS16200 ec017b6635f84833a979bdf133370b49 320 Pfam PF00698 Acyl transferase domain 9 282 7.2E-36 T 29-03-2018 IPR014043 Acyl transferase THSYN_RS18360 ff060d73554c897f31e80717e6a88f20 203 Pfam PF12263 Protein of unknown function (DUF3611) 15 191 1.9E-36 T 29-03-2018 IPR022051 Protein of unknown function DUF3611 THSYN_RS06470 7920cb85a13004c4d2df7719b850a9c1 282 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 41 260 1.1E-44 T 29-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system THSYN_RS17205 fda11c2c0cc4a2757c93285e44d49a72 297 SUPERFAMILY SSF53167 8 275 2.23E-90 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 THSYN_RS17205 fda11c2c0cc4a2757c93285e44d49a72 297 Pfam PF01048 Phosphorylase superfamily 10 246 1.3E-38 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 THSYN_RS17205 fda11c2c0cc4a2757c93285e44d49a72 297 Gene3D G3DSA:3.40.50.1580 1 271 2.9E-48 T 29-03-2018 THSYN_RS17205 fda11c2c0cc4a2757c93285e44d49a72 297 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 8 271 40.612 T 29-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 THSYN_RS17205 fda11c2c0cc4a2757c93285e44d49a72 297 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 56 96 - T 29-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 THSYN_RS17205 fda11c2c0cc4a2757c93285e44d49a72 297 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 10 247 3.3E-89 T 29-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 THSYN_RS22915 0cef2a50a59d352ce4cc402e37af1659 481 SMART SM00851 36 126 1.4E-8 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain THSYN_RS22915 0cef2a50a59d352ce4cc402e37af1659 481 Gene3D G3DSA:3.40.50.1380 14 155 2.6E-23 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain THSYN_RS22915 0cef2a50a59d352ce4cc402e37af1659 481 Pfam PF02142 MGS-like domain 37 126 4.1E-10 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain THSYN_RS22915 0cef2a50a59d352ce4cc402e37af1659 481 Gene3D G3DSA:3.20.20.140 174 469 3.0E-33 T 29-03-2018 THSYN_RS22915 0cef2a50a59d352ce4cc402e37af1659 481 SUPERFAMILY SSF52335 23 141 2.88E-18 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain THSYN_RS22915 0cef2a50a59d352ce4cc402e37af1659 481 Pfam PF01979 Amidohydrolase family 173 455 8.4E-11 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 THSYN_RS22915 0cef2a50a59d352ce4cc402e37af1659 481 SUPERFAMILY SSF51556 173 458 3.1E-56 T 29-03-2018 IPR032466 Metal-dependent hydrolase THSYN_RS19300 93db53f12e88887b578d75a913e1519d 296 Pfam PF12146 Serine aminopeptidase, S33 66 183 6.6E-16 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 THSYN_RS19300 93db53f12e88887b578d75a913e1519d 296 Gene3D G3DSA:3.40.50.1820 36 288 9.0E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS19300 93db53f12e88887b578d75a913e1519d 296 SUPERFAMILY SSF53474 29 283 1.07E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS29180 c8cc2485a172f7809354c6ff8c5e5ef7 83 PRINTS PR00124 ATP synthase C subunit signature 38 53 3.7E-10 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29180 c8cc2485a172f7809354c6ff8c5e5ef7 83 PRINTS PR00124 ATP synthase C subunit signature 55 80 3.7E-10 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29180 c8cc2485a172f7809354c6ff8c5e5ef7 83 PRINTS PR00124 ATP synthase C subunit signature 17 36 3.7E-10 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29180 c8cc2485a172f7809354c6ff8c5e5ef7 83 Gene3D G3DSA:1.20.20.10 9 82 6.4E-15 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 THSYN_RS29180 c8cc2485a172f7809354c6ff8c5e5ef7 83 Pfam PF00137 ATP synthase subunit C 16 79 3.2E-10 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 THSYN_RS29180 c8cc2485a172f7809354c6ff8c5e5ef7 83 Hamap MF_01396 ATP synthase subunit c [atpH]. 15 80 13.631 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29180 c8cc2485a172f7809354c6ff8c5e5ef7 83 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 26 82 5.2E-27 T 29-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THSYN_RS29180 c8cc2485a172f7809354c6ff8c5e5ef7 83 ProSitePatterns PS00605 ATP synthase c subunit signature. 45 66 - T 29-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS29180 c8cc2485a172f7809354c6ff8c5e5ef7 83 SUPERFAMILY SSF81333 10 82 8.11E-17 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 THSYN_RS26830 59866adbcb07ccac6a7f421040b3f39b 223 Gene3D G3DSA:3.40.50.720 3 97 2.6E-7 T 29-03-2018 THSYN_RS26830 59866adbcb07ccac6a7f421040b3f39b 223 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 166 199 1.6E-8 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS26830 59866adbcb07ccac6a7f421040b3f39b 223 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 173 201 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 THSYN_RS26830 59866adbcb07ccac6a7f421040b3f39b 223 Gene3D G3DSA:2.160.10.10 98 222 1.9E-31 T 29-03-2018 THSYN_RS26830 59866adbcb07ccac6a7f421040b3f39b 223 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 7 213 1.3E-54 T 29-03-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like THSYN_RS26830 59866adbcb07ccac6a7f421040b3f39b 223 SUPERFAMILY SSF51161 80 217 1.11E-39 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS17800 904e2d4c949e5dfc8995e29b5246f536 93 Pfam PF13488 Glycine zipper 31 72 8.2E-11 T 29-03-2018 THSYN_RS05260 5bb86686f5778d64051d8975ba33eaee 622 SUPERFAMILY SSF81606 236 490 1.57E-11 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS05260 5bb86686f5778d64051d8975ba33eaee 622 Gene3D G3DSA:3.60.40.10 216 493 2.5E-11 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS05260 5bb86686f5778d64051d8975ba33eaee 622 Pfam PF13672 Protein phosphatase 2C 232 476 9.2E-45 T 29-03-2018 THSYN_RS13225 bb0bc11cfe4ea12a1f504b598cb187e6 108 Pfam PF00085 Thioredoxin 6 106 2.0E-32 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 THSYN_RS13225 bb0bc11cfe4ea12a1f504b598cb187e6 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THSYN_RS13225 bb0bc11cfe4ea12a1f504b598cb187e6 108 PIRSF PIRSF000077 2 108 2.5E-43 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THSYN_RS13225 bb0bc11cfe4ea12a1f504b598cb187e6 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 7.3E-38 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THSYN_RS13225 bb0bc11cfe4ea12a1f504b598cb187e6 108 Gene3D G3DSA:3.40.30.10 1 108 2.6E-33 T 29-03-2018 THSYN_RS13225 bb0bc11cfe4ea12a1f504b598cb187e6 108 SUPERFAMILY SSF52833 5 108 1.54E-37 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS13225 bb0bc11cfe4ea12a1f504b598cb187e6 108 PRINTS PR00421 Thioredoxin family signature 24 32 1.5E-9 T 29-03-2018 THSYN_RS13225 bb0bc11cfe4ea12a1f504b598cb187e6 108 PRINTS PR00421 Thioredoxin family signature 32 41 1.5E-9 T 29-03-2018 THSYN_RS13225 bb0bc11cfe4ea12a1f504b598cb187e6 108 PRINTS PR00421 Thioredoxin family signature 72 83 1.5E-9 T 29-03-2018 THSYN_RS25975 61c6e6f43a5ce3216522681f743812c7 356 SUPERFAMILY SSF55326 12 175 2.27E-49 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS25975 61c6e6f43a5ce3216522681f743812c7 356 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 12 349 45.504 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THSYN_RS25975 61c6e6f43a5ce3216522681f743812c7 356 Gene3D G3DSA:3.30.1330.10 42 167 4.4E-52 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS25975 61c6e6f43a5ce3216522681f743812c7 356 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 12 339 4.3E-131 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THSYN_RS25975 61c6e6f43a5ce3216522681f743812c7 356 Gene3D G3DSA:3.90.650.10 178 351 1.4E-57 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS25975 61c6e6f43a5ce3216522681f743812c7 356 SUPERFAMILY SSF56042 178 346 2.69E-57 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS25975 61c6e6f43a5ce3216522681f743812c7 356 Pfam PF02769 AIR synthase related protein, C-terminal domain 182 341 5.4E-33 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain THSYN_RS25975 61c6e6f43a5ce3216522681f743812c7 356 Pfam PF00586 AIR synthase related protein, N-terminal domain 64 169 1.3E-13 T 29-03-2018 IPR016188 PurM-like, N-terminal domain THSYN_RS05545 22224fbaac564f124f891467f489984f 346 SUPERFAMILY SSF52151 18 90 6.8E-37 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS05545 22224fbaac564f124f891467f489984f 346 SUPERFAMILY SSF52151 121 330 6.8E-37 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS05545 22224fbaac564f124f891467f489984f 346 Pfam PF01734 Patatin-like phospholipase 21 230 5.0E-27 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 THSYN_RS05545 22224fbaac564f124f891467f489984f 346 Gene3D G3DSA:3.40.1090.10 9 324 9.2E-36 T 29-03-2018 THSYN_RS18975 1a828e978fb05d04a980d8673c51ab07 583 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 559 568 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THSYN_RS18975 1a828e978fb05d04a980d8673c51ab07 583 SUPERFAMILY SSF56762 19 568 1.96E-166 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS18975 1a828e978fb05d04a980d8673c51ab07 583 Pfam PF00374 Nickel-dependent hydrogenase 56 568 5.7E-209 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THSYN_RS18975 1a828e978fb05d04a980d8673c51ab07 583 Gene3D G3DSA:1.10.645.10 16 568 8.8E-179 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS18975 1a828e978fb05d04a980d8673c51ab07 583 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 56 81 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THSYN_RS18560 10f6ac5dd69e3dccf85512f4820c099c 383 Gene3D G3DSA:1.10.443.10 202 374 1.1E-16 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS18560 10f6ac5dd69e3dccf85512f4820c099c 383 Gene3D G3DSA:1.10.150.130 76 201 2.8E-17 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS18560 10f6ac5dd69e3dccf85512f4820c099c 383 SUPERFAMILY SSF56349 86 373 4.12E-47 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS18560 10f6ac5dd69e3dccf85512f4820c099c 383 Pfam PF13356 Arm DNA-binding domain 7 73 7.9E-12 T 29-03-2018 IPR025166 Integrase, DNA-binding domain THSYN_RS18560 10f6ac5dd69e3dccf85512f4820c099c 383 Pfam PF00589 Phage integrase family 223 330 2.5E-12 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS18125 a52e624e8b873086d88a0f52e6c2b1ef 233 Gene3D G3DSA:3.40.1800.10 72 152 3.5E-5 T 29-03-2018 THSYN_RS18030 c50a35cf5c655cd2157bc10b022deff0 188 SMART SM00867 23 186 1.3E-59 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THSYN_RS18030 c50a35cf5c655cd2157bc10b022deff0 188 Pfam PF04264 YceI-like domain 24 185 2.0E-36 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THSYN_RS18030 c50a35cf5c655cd2157bc10b022deff0 188 SUPERFAMILY SSF101874 23 187 4.58E-51 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THSYN_RS18030 c50a35cf5c655cd2157bc10b022deff0 188 Gene3D G3DSA:2.40.128.110 22 188 8.8E-45 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THSYN_RS17900 ae9db7afe1a7fcdf40e4ab864618bc56 90 Pfam PF00216 Bacterial DNA-binding protein 1 89 1.9E-32 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS17900 ae9db7afe1a7fcdf40e4ab864618bc56 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 THSYN_RS17900 ae9db7afe1a7fcdf40e4ab864618bc56 90 Gene3D G3DSA:4.10.520.10 1 90 9.1E-34 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS17900 ae9db7afe1a7fcdf40e4ab864618bc56 90 SMART SM00411 1 90 2.0E-41 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS17900 ae9db7afe1a7fcdf40e4ab864618bc56 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 4.7E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS17900 ae9db7afe1a7fcdf40e4ab864618bc56 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 4.7E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS17900 ae9db7afe1a7fcdf40e4ab864618bc56 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 4.7E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS17900 ae9db7afe1a7fcdf40e4ab864618bc56 90 SUPERFAMILY SSF47729 1 90 1.47E-30 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS29765 0a12432babbd7caebfb921c4fe2b8ad6 204 Pfam PF00936 BMC domain 142 198 9.8E-7 T 29-03-2018 IPR000249 Microcompartment protein, bacteria THSYN_RS29765 0a12432babbd7caebfb921c4fe2b8ad6 204 SMART SM00877 138 203 6.6E-13 T 29-03-2018 IPR000249 Microcompartment protein, bacteria THSYN_RS29765 0a12432babbd7caebfb921c4fe2b8ad6 204 SUPERFAMILY SSF143414 138 201 3.14E-9 T 29-03-2018 THSYN_RS12785 0f158fcb454b662bc8bb462c5eed009c 227 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 62 201 5.0E-28 T 29-03-2018 THSYN_RS01795 86be192d765cf8c30e9aedb783094783 365 Gene3D G3DSA:1.25.40.10 151 175 6.2E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01795 86be192d765cf8c30e9aedb783094783 365 Gene3D G3DSA:1.25.40.10 176 269 2.0E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01795 86be192d765cf8c30e9aedb783094783 365 SMART SM00028 207 242 190.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01795 86be192d765cf8c30e9aedb783094783 365 SMART SM00028 105 138 0.034 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01795 86be192d765cf8c30e9aedb783094783 365 SMART SM00028 173 206 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01795 86be192d765cf8c30e9aedb783094783 365 SMART SM00028 139 172 0.26 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01795 86be192d765cf8c30e9aedb783094783 365 SUPERFAMILY SSF48452 101 244 4.38E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01795 86be192d765cf8c30e9aedb783094783 365 Gene3D G3DSA:1.25.40.10 116 150 1.5E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01795 86be192d765cf8c30e9aedb783094783 365 Gene3D G3DSA:1.10.150.160 36 115 0.0049 T 29-03-2018 THSYN_RS01795 86be192d765cf8c30e9aedb783094783 365 Pfam PF13181 Tetratricopeptide repeat 143 171 0.082 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01795 86be192d765cf8c30e9aedb783094783 365 Pfam PF13181 Tetratricopeptide repeat 105 137 0.03 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS01795 86be192d765cf8c30e9aedb783094783 365 Pfam PF13432 Tetratricopeptide repeat 178 241 2.4E-7 T 29-03-2018 THSYN_RS21355 0efd0ec92c4759f9e10a45f0ef487ab4 556 SUPERFAMILY SSF56935 431 543 3.22E-6 T 29-03-2018 THSYN_RS21355 0efd0ec92c4759f9e10a45f0ef487ab4 556 Gene3D G3DSA:2.40.160.10 372 555 4.4E-7 T 29-03-2018 THSYN_RS21355 0efd0ec92c4759f9e10a45f0ef487ab4 556 TIGRFAM TIGR03016 pepcterm_hypo_1: uncharacterized protein, PEP-CTERM system associated 75 553 3.2E-40 T 29-03-2018 IPR017467 Conserved hypothetical protein CHP03016, PEP-CTERM THSYN_RS02860 a50d2822004a43ac9170e79067effdac 101 Pfam PF01381 Helix-turn-helix 46 81 1.1E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS02860 a50d2822004a43ac9170e79067effdac 101 SUPERFAMILY SSF47413 42 87 4.86E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS02860 a50d2822004a43ac9170e79067effdac 101 Gene3D G3DSA:3.30.1190.10 63 93 5.3E-6 T 29-03-2018 THSYN_RS02860 a50d2822004a43ac9170e79067effdac 101 SMART SM00530 43 101 2.8E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS02860 a50d2822004a43ac9170e79067effdac 101 Gene3D G3DSA:1.10.10.60 16 62 4.7E-8 T 29-03-2018 THSYN_RS32680 76266081de379df7aa0fd1ff3e136c25 252 Pfam PF06271 RDD family 21 137 1.6E-10 T 29-03-2018 IPR010432 RDD THSYN_RS01570 a71ee0e31ba55411a0c496ce71f908c4 347 Pfam PF06250 Protein of unknown function (DUF1016) 21 331 1.6E-116 T 29-03-2018 IPR009362 Protein of unknown function DUF1016 THSYN_RS20600 10d7694f5de37b715c16c1675768f5e6 177 SUPERFAMILY SSF56420 3 161 4.58E-61 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS20600 10d7694f5de37b715c16c1675768f5e6 177 Pfam PF01327 Polypeptide deformylase 5 152 1.4E-49 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS20600 10d7694f5de37b715c16c1675768f5e6 177 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 160 2.3E-56 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS20600 10d7694f5de37b715c16c1675768f5e6 177 Hamap MF_00163 Peptide deformylase [def]. 2 162 30.207 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS20600 10d7694f5de37b715c16c1675768f5e6 177 Gene3D G3DSA:3.90.45.10 1 171 1.2E-61 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS20600 10d7694f5de37b715c16c1675768f5e6 177 PRINTS PR01576 Peptide deformylase signature 120 149 3.3E-39 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS20600 10d7694f5de37b715c16c1675768f5e6 177 PRINTS PR01576 Peptide deformylase signature 89 100 3.3E-39 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS20600 10d7694f5de37b715c16c1675768f5e6 177 PRINTS PR01576 Peptide deformylase signature 101 119 3.3E-39 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS20600 10d7694f5de37b715c16c1675768f5e6 177 PRINTS PR01576 Peptide deformylase signature 33 62 3.3E-39 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS20600 10d7694f5de37b715c16c1675768f5e6 177 PIRSF PIRSF004749 1 173 5.7E-57 T 29-03-2018 IPR023635 Peptide deformylase THSYN_RS06005 4744c9c8640c137132be73f981cb8777 139 SUPERFAMILY SSF50630 33 118 9.76E-8 T 29-03-2018 IPR021109 Aspartic peptidase domain THSYN_RS06005 4744c9c8640c137132be73f981cb8777 139 Gene3D G3DSA:2.40.70.10 24 126 1.6E-11 T 29-03-2018 IPR021109 Aspartic peptidase domain THSYN_RS19530 006af032dbdda9cc9c1b2dc8db4b3ebc 438 SUPERFAMILY SSF55347 138 303 1.11E-53 T 29-03-2018 THSYN_RS19530 006af032dbdda9cc9c1b2dc8db4b3ebc 438 Pfam PF01842 ACT domain 355 421 5.4E-13 T 29-03-2018 IPR002912 ACT domain THSYN_RS19530 006af032dbdda9cc9c1b2dc8db4b3ebc 438 PIRSF PIRSF000098 1 436 1.8E-164 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 THSYN_RS19530 006af032dbdda9cc9c1b2dc8db4b3ebc 438 Gene3D G3DSA:3.30.360.10 150 300 1.2E-56 T 29-03-2018 THSYN_RS19530 006af032dbdda9cc9c1b2dc8db4b3ebc 438 Pfam PF00742 Homoserine dehydrogenase 138 316 5.4E-64 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 THSYN_RS19530 006af032dbdda9cc9c1b2dc8db4b3ebc 438 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 THSYN_RS19530 006af032dbdda9cc9c1b2dc8db4b3ebc 438 Gene3D G3DSA:3.30.70.260 351 432 1.3E-19 T 29-03-2018 THSYN_RS19530 006af032dbdda9cc9c1b2dc8db4b3ebc 438 SUPERFAMILY SSF55021 354 427 3.23E-13 T 29-03-2018 THSYN_RS19530 006af032dbdda9cc9c1b2dc8db4b3ebc 438 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 3.0E-16 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 THSYN_RS19530 006af032dbdda9cc9c1b2dc8db4b3ebc 438 SUPERFAMILY SSF51735 1 159 2.36E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS19530 006af032dbdda9cc9c1b2dc8db4b3ebc 438 Gene3D G3DSA:3.40.50.720 1 149 8.9E-26 T 29-03-2018 THSYN_RS13795 49146e7448c2825cb3a5ae0d66f45e5e 497 Pfam PF13598 Domain of unknown function (DUF4139) 207 495 4.5E-10 T 29-03-2018 IPR011935 Conserved hypothetical protein CHP02231 THSYN_RS09540 415f9cedb89e827587eca64394c3fafb 361 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 95 271 1.6E-14 T 29-03-2018 IPR000477 Reverse transcriptase domain THSYN_RS09540 415f9cedb89e827587eca64394c3fafb 361 Gene3D G3DSA:3.30.70.270 135 273 7.2E-12 T 29-03-2018 THSYN_RS09540 415f9cedb89e827587eca64394c3fafb 361 SUPERFAMILY SSF56672 91 295 2.31E-22 T 29-03-2018 THSYN_RS12175 5fb0d1d6fed07a1531749d894ee6db08 490 Pfam PF08308 PEGA domain 33 91 8.7E-8 T 29-03-2018 IPR013229 PEGA THSYN_RS12175 5fb0d1d6fed07a1531749d894ee6db08 490 Pfam PF03781 Sulfatase-modifying factor enzyme 1 248 486 9.4E-52 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS12175 5fb0d1d6fed07a1531749d894ee6db08 490 Gene3D G3DSA:3.90.1580.10 311 490 6.5E-47 T 29-03-2018 THSYN_RS12175 5fb0d1d6fed07a1531749d894ee6db08 490 Gene3D G3DSA:3.90.1580.10 233 310 2.5E-13 T 29-03-2018 THSYN_RS12175 5fb0d1d6fed07a1531749d894ee6db08 490 SUPERFAMILY SSF56436 245 488 1.04E-65 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS12175 5fb0d1d6fed07a1531749d894ee6db08 490 Gene3D G3DSA:2.60.40.1120 27 100 5.2E-5 T 29-03-2018 THSYN_RS07470 76e0c4d6eaae7f8a0f41bfae1f73b0c5 184 Pfam PF00578 AhpC/TSA family 48 157 5.9E-19 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THSYN_RS07470 76e0c4d6eaae7f8a0f41bfae1f73b0c5 184 SUPERFAMILY SSF52833 43 166 5.68E-32 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS07470 76e0c4d6eaae7f8a0f41bfae1f73b0c5 184 Gene3D G3DSA:3.40.30.10 39 176 1.9E-27 T 29-03-2018 THSYN_RS13510 4e7ab585bc0e31cd509c0864c254a43d 405 Pfam PF13476 AAA domain 5 209 1.2E-22 T 29-03-2018 THSYN_RS13510 4e7ab585bc0e31cd509c0864c254a43d 405 SUPERFAMILY SSF52540 1 331 8.82E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13510 4e7ab585bc0e31cd509c0864c254a43d 405 SMART SM00382 22 389 2.0E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS13510 4e7ab585bc0e31cd509c0864c254a43d 405 Gene3D G3DSA:3.40.50.300 1 341 8.6E-34 T 29-03-2018 THSYN_RS28510 da4ca22ebf7da45ba3bd89c516477581 609 Pfam PF00474 Sodium:solute symporter family 39 348 1.7E-37 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THSYN_RS28510 da4ca22ebf7da45ba3bd89c516477581 609 Pfam PF00474 Sodium:solute symporter family 394 531 1.2E-16 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 234 313 1.6E-32 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 Gene3D G3DSA:3.40.50.700 56 233 3.7E-45 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 PIRSF PIRSF000310 11 365 1.3E-135 T 29-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 53 75 4.0E-73 T 29-03-2018 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 166 190 4.0E-73 T 29-03-2018 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 263 289 4.0E-73 T 29-03-2018 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 76 100 4.0E-73 T 29-03-2018 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 291 304 4.0E-73 T 29-03-2018 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 221 238 4.0E-73 T 29-03-2018 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 239 257 4.0E-73 T 29-03-2018 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 195 218 4.0E-73 T 29-03-2018 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 68 214 5.7E-30 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 SUPERFAMILY SSF56770 53 317 3.4E-84 T 29-03-2018 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 11 323 8.7E-124 T 29-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 22 40 2.8E-5 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THSYN_RS28320 aefcbd720de67cf3ee94e48d283876f1 371 Gene3D G3DSA:4.10.480.10 234 316 3.8E-34 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THSYN_RS15475 4a0bafffee1ed845d041677d3127e7ff 129 Pfam PF04965 Gene 25-like lysozyme 30 112 5.0E-21 T 29-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD THSYN_RS15475 4a0bafffee1ed845d041677d3127e7ff 129 Gene3D G3DSA:3.10.450.40 1 129 1.8E-38 T 29-03-2018 THSYN_RS15475 4a0bafffee1ed845d041677d3127e7ff 129 SUPERFAMILY SSF160719 27 128 2.48E-29 T 29-03-2018 THSYN_RS18705 9a6119528e8dad05ce3fd8357994ef93 573 Pfam PF03235 Protein of unknown function DUF262 16 210 5.0E-34 T 29-03-2018 IPR004919 Domain of unknown function DUF262 THSYN_RS18705 9a6119528e8dad05ce3fd8357994ef93 573 Pfam PF07510 Protein of unknown function (DUF1524) 424 564 8.6E-20 T 29-03-2018 IPR011089 Domain of unknown function DUF1524 THSYN_RS03245 fd28b9f50a140bc7317d5c2986578ea8 357 SUPERFAMILY SSF56796 4 355 8.64E-120 T 29-03-2018 THSYN_RS03245 fd28b9f50a140bc7317d5c2986578ea8 357 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 15 348 1.9E-115 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 THSYN_RS03245 fd28b9f50a140bc7317d5c2986578ea8 357 Pfam PF01761 3-dehydroquinate synthase 66 324 3.5E-108 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 THSYN_RS03245 fd28b9f50a140bc7317d5c2986578ea8 357 Gene3D G3DSA:1.20.1090.10 172 356 5.0E-68 T 29-03-2018 THSYN_RS03245 fd28b9f50a140bc7317d5c2986578ea8 357 Gene3D G3DSA:3.40.50.1970 4 171 6.3E-50 T 29-03-2018 THSYN_RS03245 fd28b9f50a140bc7317d5c2986578ea8 357 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 3 357 43.047 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 THSYN_RS03245 fd28b9f50a140bc7317d5c2986578ea8 357 PIRSF PIRSF001455 8 355 8.9E-108 T 29-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 THSYN_RS22255 55994c124782caea1e0005125a654f6d 319 Pfam PF00294 pfkB family carbohydrate kinase 26 306 1.6E-30 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB THSYN_RS22255 55994c124782caea1e0005125a654f6d 319 SUPERFAMILY SSF53613 21 306 2.03E-49 T 29-03-2018 IPR029056 Ribokinase-like THSYN_RS22255 55994c124782caea1e0005125a654f6d 319 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 265 278 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 THSYN_RS22255 55994c124782caea1e0005125a654f6d 319 Gene3D G3DSA:3.40.1190.20 20 311 2.9E-59 T 29-03-2018 IPR029056 Ribokinase-like THSYN_RS13630 7421040b35aabf2f095992befcaa6706 1563 Gene3D G3DSA:3.40.50.410 120 874 1.2E-4 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS13630 7421040b35aabf2f095992befcaa6706 1563 SUPERFAMILY SSF50998 1059 1116 2.88E-8 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS13630 7421040b35aabf2f095992befcaa6706 1563 SUPERFAMILY SSF50998 1213 1295 2.88E-8 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THSYN_RS13630 7421040b35aabf2f095992befcaa6706 1563 Gene3D G3DSA:2.140.10.10 1008 1170 0.028 T 29-03-2018 THSYN_RS13630 7421040b35aabf2f095992befcaa6706 1563 Gene3D G3DSA:2.140.10.10 1171 1548 2.5E-8 T 29-03-2018 THSYN_RS13630 7421040b35aabf2f095992befcaa6706 1563 Pfam PF05567 Neisseria PilC beta-propeller domain 1024 1378 1.5E-68 T 29-03-2018 IPR008707 PilC beta-propeller domain THSYN_RS31880 9a1fb411e4f8f33ecb01f3dad91dbb79 648 SUPERFAMILY SSF100950 276 519 3.43E-75 T 29-03-2018 THSYN_RS31880 9a1fb411e4f8f33ecb01f3dad91dbb79 648 Pfam PF01144 Coenzyme A transferase 12 244 5.0E-32 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 THSYN_RS31880 9a1fb411e4f8f33ecb01f3dad91dbb79 648 Gene3D G3DSA:3.40.1080.10 276 523 1.1E-52 T 29-03-2018 THSYN_RS31880 9a1fb411e4f8f33ecb01f3dad91dbb79 648 SMART SM00882 7 244 1.5E-59 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 THSYN_RS31880 9a1fb411e4f8f33ecb01f3dad91dbb79 648 Gene3D G3DSA:3.40.1080.10 8 269 3.4E-79 T 29-03-2018 THSYN_RS31880 9a1fb411e4f8f33ecb01f3dad91dbb79 648 SUPERFAMILY SSF100950 10 254 1.4E-85 T 29-03-2018 THSYN_RS25165 58216995d8771ec54ba730dfdd293814 319 Pfam PF07507 WavE lipopolysaccharide synthesis 9 261 3.5E-40 T 29-03-2018 IPR011122 WavE lipopolysaccharide synthesis THSYN_RS31015 305c1f201f37e4e63879a4368d4b0921 259 Gene3D G3DSA:3.40.50.720 6 259 2.5E-41 T 29-03-2018 THSYN_RS31015 305c1f201f37e4e63879a4368d4b0921 259 SUPERFAMILY SSF51735 10 257 1.82E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS31015 305c1f201f37e4e63879a4368d4b0921 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 256 1.3E-75 T 29-03-2018 THSYN_RS31015 305c1f201f37e4e63879a4368d4b0921 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 5.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS31015 305c1f201f37e4e63879a4368d4b0921 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 5.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS31015 305c1f201f37e4e63879a4368d4b0921 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 5.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS31015 305c1f201f37e4e63879a4368d4b0921 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 5.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS31015 305c1f201f37e4e63879a4368d4b0921 259 PIRSF PIRSF000094 6 259 2.3E-80 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THSYN_RS05360 d8a59d47c7075b0486e8294b7fcde8aa 293 SUPERFAMILY SSF51735 16 267 5.0E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS05360 d8a59d47c7075b0486e8294b7fcde8aa 293 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THSYN_RS05360 d8a59d47c7075b0486e8294b7fcde8aa 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 4.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS05360 d8a59d47c7075b0486e8294b7fcde8aa 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 4.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS05360 d8a59d47c7075b0486e8294b7fcde8aa 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 4.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS05360 d8a59d47c7075b0486e8294b7fcde8aa 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 4.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS05360 d8a59d47c7075b0486e8294b7fcde8aa 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 4.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS05360 d8a59d47c7075b0486e8294b7fcde8aa 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 2.3E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS05360 d8a59d47c7075b0486e8294b7fcde8aa 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 2.3E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS05360 d8a59d47c7075b0486e8294b7fcde8aa 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.3E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS05360 d8a59d47c7075b0486e8294b7fcde8aa 293 Gene3D G3DSA:3.40.50.720 14 277 5.7E-56 T 29-03-2018 THSYN_RS05360 d8a59d47c7075b0486e8294b7fcde8aa 293 Pfam PF00106 short chain dehydrogenase 17 200 8.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS29740 495d9b95c050ae4fb8b27c8e3a0b8870 106 SUPERFAMILY SSF143414 9 95 3.66E-28 T 29-03-2018 THSYN_RS29740 495d9b95c050ae4fb8b27c8e3a0b8870 106 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 26 45 - T 29-03-2018 IPR020808 Bacterial microcompartments protein, conserved site THSYN_RS29740 495d9b95c050ae4fb8b27c8e3a0b8870 106 SMART SM00877 8 85 8.5E-31 T 29-03-2018 IPR000249 Microcompartment protein, bacteria THSYN_RS29740 495d9b95c050ae4fb8b27c8e3a0b8870 106 Pfam PF00936 BMC domain 9 85 9.3E-26 T 29-03-2018 IPR000249 Microcompartment protein, bacteria THSYN_RS29740 495d9b95c050ae4fb8b27c8e3a0b8870 106 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 9 70 3.0E-19 T 29-03-2018 THSYN_RS29200 6e3ad61dc80b0dba09af312945b65faa 262 PIRSF PIRSF009320 2 69 1.9E-15 T 29-03-2018 THSYN_RS29200 6e3ad61dc80b0dba09af312945b65faa 262 PIRSF PIRSF009320 90 261 5.0E-10 T 29-03-2018 THSYN_RS29200 6e3ad61dc80b0dba09af312945b65faa 262 SUPERFAMILY SSF52540 1 257 1.5E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS29200 6e3ad61dc80b0dba09af312945b65faa 262 Gene3D G3DSA:3.40.50.300 2 262 2.7E-59 T 29-03-2018 THSYN_RS29200 6e3ad61dc80b0dba09af312945b65faa 262 Pfam PF13614 AAA domain 2 180 1.1E-58 T 29-03-2018 IPR025669 AAA domain THSYN_RS08615 e29265107f1c0d80441af9ffedca446f 82 Gene3D G3DSA:1.10.1220.10 2 39 3.2E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS25100 3f43132226a2f956ffa28bfac675e382 381 SUPERFAMILY SSF53756 12 372 1.67E-40 T 29-03-2018 THSYN_RS25100 3f43132226a2f956ffa28bfac675e382 381 Gene3D G3DSA:3.40.50.2000 8 201 1.9E-10 T 29-03-2018 THSYN_RS25100 3f43132226a2f956ffa28bfac675e382 381 Pfam PF13579 Glycosyl transferase 4-like domain 10 191 3.3E-7 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS25100 3f43132226a2f956ffa28bfac675e382 381 Pfam PF13692 Glycosyl transferases group 1 208 338 9.9E-17 T 29-03-2018 THSYN_RS25100 3f43132226a2f956ffa28bfac675e382 381 Gene3D G3DSA:3.40.50.2000 202 349 6.6E-23 T 29-03-2018 THSYN_RS20985 c2363e25bc806d23523d4ca50071506c 389 Pfam PF13173 AAA domain 18 133 1.2E-20 T 29-03-2018 THSYN_RS20985 c2363e25bc806d23523d4ca50071506c 389 Gene3D G3DSA:3.40.50.300 13 126 1.4E-5 T 29-03-2018 THSYN_RS20985 c2363e25bc806d23523d4ca50071506c 389 SUPERFAMILY SSF52540 11 133 4.88E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS20985 c2363e25bc806d23523d4ca50071506c 389 Pfam PF13635 Domain of unknown function (DUF4143) 175 334 2.4E-29 T 29-03-2018 IPR025420 Domain of unknown function DUF4143 THSYN_RS31760 03fa8b8de58220c4b3ba6acf01a913b8 482 Pfam PF11855 Protein of unknown function (DUF3375) 9 480 4.1E-156 T 29-03-2018 IPR021804 Protein of unknown function DUF3375 THSYN_RS05895 b1e4055cd484f701510eb45737dd6d6f 218 Pfam PF13511 Domain of unknown function (DUF4124) 15 66 5.5E-5 T 29-03-2018 IPR025392 Domain of unknown function DUF4124 THSYN_RS32705 12555cbf9cbf722b6c8cde04f73b87a7 214 Gene3D G3DSA:1.10.101.10 132 212 6.2E-11 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS32705 12555cbf9cbf722b6c8cde04f73b87a7 214 Pfam PF01471 Putative peptidoglycan binding domain 160 205 1.9E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS32705 12555cbf9cbf722b6c8cde04f73b87a7 214 SUPERFAMILY SSF47090 145 207 2.04E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS32705 12555cbf9cbf722b6c8cde04f73b87a7 214 Gene3D G3DSA:3.10.350.10 3 56 8.7E-10 T 29-03-2018 THSYN_RS06780 4e5d38a2793356aaa8fb5cd8d539db93 219 SUPERFAMILY SSF159594 40 210 7.06E-30 T 29-03-2018 THSYN_RS06780 4e5d38a2793356aaa8fb5cd8d539db93 219 Gene3D G3DSA:3.40.50.10610 26 217 6.6E-30 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component THSYN_RS06780 4e5d38a2793356aaa8fb5cd8d539db93 219 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 42 202 3.4E-14 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component THSYN_RS28875 acfaf1fb6519be92a57b316cdff73a53 352 Gene3D G3DSA:3.40.50.150 6 166 1.7E-36 T 29-03-2018 THSYN_RS28875 acfaf1fb6519be92a57b316cdff73a53 352 Gene3D G3DSA:3.90.120.10 167 313 1.4E-14 T 29-03-2018 THSYN_RS28875 acfaf1fb6519be92a57b316cdff73a53 352 Pfam PF00145 C-5 cytosine-specific DNA methylase 6 174 6.2E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS28875 acfaf1fb6519be92a57b316cdff73a53 352 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 157 170 7.0E-9 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THSYN_RS28875 acfaf1fb6519be92a57b316cdff73a53 352 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 7 23 7.0E-9 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THSYN_RS28875 acfaf1fb6519be92a57b316cdff73a53 352 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 111 125 7.0E-9 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THSYN_RS28875 acfaf1fb6519be92a57b316cdff73a53 352 SUPERFAMILY SSF53335 4 323 1.22E-51 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS16875 4028dd4728a639a63b4c7ebcc7a33162 408 SUPERFAMILY SSF56436 158 407 8.01E-70 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS16875 4028dd4728a639a63b4c7ebcc7a33162 408 Pfam PF03781 Sulfatase-modifying factor enzyme 1 159 406 9.0E-61 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS16875 4028dd4728a639a63b4c7ebcc7a33162 408 Gene3D G3DSA:3.90.1580.10 147 408 4.7E-74 T 29-03-2018 THSYN_RS17045 a8793569e342bf4dfbba448b071cbb22 113 SUPERFAMILY SSF52091 5 98 1.65E-22 T 29-03-2018 IPR002645 STAS domain THSYN_RS17045 a8793569e342bf4dfbba448b071cbb22 113 Pfam PF13466 STAS domain 13 92 8.0E-16 T 29-03-2018 IPR002645 STAS domain THSYN_RS17045 a8793569e342bf4dfbba448b071cbb22 113 Gene3D G3DSA:3.30.750.24 4 104 1.4E-16 T 29-03-2018 IPR002645 STAS domain THSYN_RS21010 738ec7447c3231a270407ec2bc72b508 194 SMART SM00155 89 116 0.0019 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 THSYN_RS21010 738ec7447c3231a270407ec2bc72b508 194 Pfam PF13091 PLD-like domain 20 126 5.0E-8 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THSYN_RS21010 738ec7447c3231a270407ec2bc72b508 194 Gene3D G3DSA:3.30.870.10 12 170 5.5E-10 T 29-03-2018 THSYN_RS21010 738ec7447c3231a270407ec2bc72b508 194 SUPERFAMILY SSF56024 14 151 2.35E-13 T 29-03-2018 THSYN_RS12010 33f7105f00fd137c4649d55b636c13dd 98 Gene3D G3DSA:3.30.2310.20 1 95 3.5E-5 T 29-03-2018 THSYN_RS12010 33f7105f00fd137c4649d55b636c13dd 98 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 91 5.2E-14 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS32045 f3ee8fbb5ebfbfd450253d4e12281788 379 Pfam PF02655 ATP-grasp domain 127 273 1.1E-16 T 29-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 THSYN_RS32045 f3ee8fbb5ebfbfd450253d4e12281788 379 Gene3D G3DSA:3.30.470.20 108 371 6.6E-15 T 29-03-2018 THSYN_RS32045 f3ee8fbb5ebfbfd450253d4e12281788 379 SUPERFAMILY SSF56059 112 305 2.12E-18 T 29-03-2018 THSYN_RS32045 f3ee8fbb5ebfbfd450253d4e12281788 379 PIRSF PIRSF016817 1 379 6.3E-94 T 29-03-2018 IPR016677 Uncharacterised conserved protein UCP016817, ATP-dependent carboligase THSYN_RS28435 99da9287ce70499f99cc671f83389963 563 Gene3D G3DSA:2.40.160.10 177 563 6.3E-49 T 29-03-2018 THSYN_RS28435 99da9287ce70499f99cc671f83389963 563 PRINTS PR00184 Neisseria sp. porin signature 377 394 2.7E-9 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 THSYN_RS28435 99da9287ce70499f99cc671f83389963 563 PRINTS PR00184 Neisseria sp. porin signature 519 543 2.7E-9 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 THSYN_RS28435 99da9287ce70499f99cc671f83389963 563 PRINTS PR00184 Neisseria sp. porin signature 231 256 2.7E-9 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 THSYN_RS28435 99da9287ce70499f99cc671f83389963 563 Pfam PF13609 Gram-negative porin 231 544 4.3E-33 T 29-03-2018 THSYN_RS28435 99da9287ce70499f99cc671f83389963 563 SUPERFAMILY SSF56935 514 563 1.47E-45 T 29-03-2018 THSYN_RS28435 99da9287ce70499f99cc671f83389963 563 SUPERFAMILY SSF56935 233 485 1.47E-45 T 29-03-2018 THSYN_RS22180 25ceee073062fef78a547f1e188e4fac 145 Gene3D G3DSA:3.30.428.10 2 142 2.6E-13 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 THSYN_RS22180 25ceee073062fef78a547f1e188e4fac 145 Pfam PF01230 HIT domain 15 99 7.8E-7 T 29-03-2018 IPR001310 Histidine triad (HIT) protein THSYN_RS22180 25ceee073062fef78a547f1e188e4fac 145 SUPERFAMILY SSF54197 4 117 3.78E-22 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 THSYN_RS04015 e20214f1b3d54b668b6b4a7c3df5fe9b 501 Gene3D G3DSA:3.20.20.70 26 369 1.6E-30 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS04015 e20214f1b3d54b668b6b4a7c3df5fe9b 501 Pfam PF04055 Radical SAM superfamily 62 242 4.5E-26 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THSYN_RS04015 e20214f1b3d54b668b6b4a7c3df5fe9b 501 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 382 480 1.7E-19 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THSYN_RS04015 e20214f1b3d54b668b6b4a7c3df5fe9b 501 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 62 73 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 THSYN_RS04015 e20214f1b3d54b668b6b4a7c3df5fe9b 501 Gene3D G3DSA:3.30.420.130 370 491 4.6E-30 T 29-03-2018 THSYN_RS04015 e20214f1b3d54b668b6b4a7c3df5fe9b 501 SUPERFAMILY SSF102114 50 266 5.1E-37 T 29-03-2018 THSYN_RS04015 e20214f1b3d54b668b6b4a7c3df5fe9b 501 SUPERFAMILY SSF53146 372 483 9.94E-28 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THSYN_RS04015 e20214f1b3d54b668b6b4a7c3df5fe9b 501 TIGRFAM TIGR01290 nifB: nitrogenase cofactor biosynthesis protein NifB 35 481 2.0E-197 T 29-03-2018 IPR005980 Nitrogenase cofactor biosynthesis protein NifB GO:0009108|GO:0009399 THSYN_RS02870 813c87d1197ea08d02f5bcefff7a7536 292 Pfam PF14236 Domain of unknown function (DUF4338) 66 289 4.3E-72 T 29-03-2018 IPR025639 Domain of unknown function DUF4338 THSYN_RS32500 813c87d1197ea08d02f5bcefff7a7536 292 Pfam PF14236 Domain of unknown function (DUF4338) 66 289 4.3E-72 T 29-03-2018 IPR025639 Domain of unknown function DUF4338 THSYN_RS28655 813c87d1197ea08d02f5bcefff7a7536 292 Pfam PF14236 Domain of unknown function (DUF4338) 66 289 4.3E-72 T 29-03-2018 IPR025639 Domain of unknown function DUF4338 THSYN_RS15350 813c87d1197ea08d02f5bcefff7a7536 292 Pfam PF14236 Domain of unknown function (DUF4338) 66 289 4.3E-72 T 29-03-2018 IPR025639 Domain of unknown function DUF4338 THSYN_RS16860 7e3d409d1fafa20cb885f6b5c9b2bb50 245 Hamap MF_01092 Cell division protein ZapD [zapD]. 1 243 28.577 T 29-03-2018 IPR009777 Cell division protein ZapD THSYN_RS16860 7e3d409d1fafa20cb885f6b5c9b2bb50 245 SUPERFAMILY SSF160950 1 243 4.58E-73 T 29-03-2018 IPR009777 Cell division protein ZapD THSYN_RS16860 7e3d409d1fafa20cb885f6b5c9b2bb50 245 Gene3D G3DSA:2.60.440.10 166 243 7.1E-26 T 29-03-2018 IPR027462 Z ring-associated protein D, C-terminal domain THSYN_RS16860 7e3d409d1fafa20cb885f6b5c9b2bb50 245 Gene3D G3DSA:1.10.3900.10 3 165 2.0E-56 T 29-03-2018 THSYN_RS16860 7e3d409d1fafa20cb885f6b5c9b2bb50 245 Pfam PF07072 Cell division protein 9 219 9.1E-72 T 29-03-2018 IPR009777 Cell division protein ZapD THSYN_RS20410 1bef871f052827e339649aac0cb3c19a 191 Pfam PF08747 Domain of unknown function (DUF1788) 68 189 1.2E-37 T 29-03-2018 IPR014858 Protein of unknown function DUF1788 THSYN_RS12585 2fb96d01a5631462c65e3e28a162d2f9 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 7 107 1.0E-22 T 29-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 THSYN_RS12585 2fb96d01a5631462c65e3e28a162d2f9 119 SMART SM00905 5 118 1.7E-30 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 THSYN_RS12585 2fb96d01a5631462c65e3e28a162d2f9 119 SUPERFAMILY SSF55620 7 118 9.45E-28 T 29-03-2018 THSYN_RS12585 2fb96d01a5631462c65e3e28a162d2f9 119 TIGRFAM TIGR00526 folB_dom: FolB domain 7 110 4.7E-22 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 THSYN_RS12585 2fb96d01a5631462c65e3e28a162d2f9 119 Gene3D G3DSA:3.30.1130.10 3 119 2.1E-31 T 29-03-2018 THSYN_RS12585 2fb96d01a5631462c65e3e28a162d2f9 119 Pfam PF02152 Dihydroneopterin aldolase 7 114 2.3E-27 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 THSYN_RS15150 d7be63f1f9342801f399d1c4565cd26e 557 Gene3D G3DSA:3.40.50.300 222 393 9.6E-9 T 29-03-2018 THSYN_RS15150 d7be63f1f9342801f399d1c4565cd26e 557 SUPERFAMILY SSF52540 221 465 6.54E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15150 d7be63f1f9342801f399d1c4565cd26e 557 Pfam PF13191 AAA ATPase domain 229 377 6.9E-9 T 29-03-2018 THSYN_RS15150 d7be63f1f9342801f399d1c4565cd26e 557 SMART SM00382 248 388 0.0083 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS23335 c4ef9084a64436dea3f45bfe6cd248a9 98 Gene3D G3DSA:3.40.1620.10 16 63 3.0E-12 T 29-03-2018 THSYN_RS23335 c4ef9084a64436dea3f45bfe6cd248a9 98 SUPERFAMILY SSF143120 17 63 1.2E-10 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS23335 c4ef9084a64436dea3f45bfe6cd248a9 98 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 17 63 2.2E-13 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS23335 c4ef9084a64436dea3f45bfe6cd248a9 98 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 18 62 6.5E-16 T 29-03-2018 THSYN_RS14100 4f071a8b63c35139d595c9f6dc72def0 358 Gene3D G3DSA:3.40.630.10 54 334 3.9E-47 T 29-03-2018 THSYN_RS14100 4f071a8b63c35139d595c9f6dc72def0 358 Pfam PF04389 Peptidase family M28 123 324 1.1E-32 T 29-03-2018 IPR007484 Peptidase M28 THSYN_RS14100 4f071a8b63c35139d595c9f6dc72def0 358 SUPERFAMILY SSF53187 59 332 5.5E-53 T 29-03-2018 THSYN_RS10585 266b28918ced55498060f84e1104e3ee 203 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 174 198 0.0037 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS26825 2c46090a6f8f843301a3124cb456c18c 369 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 363 1.7E-117 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THSYN_RS26825 2c46090a6f8f843301a3124cb456c18c 369 SUPERFAMILY SSF53383 4 367 2.95E-101 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS26825 2c46090a6f8f843301a3124cb456c18c 369 Gene3D G3DSA:3.90.1150.10 240 369 2.9E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS26825 2c46090a6f8f843301a3124cb456c18c 369 Gene3D G3DSA:3.40.640.10 1 239 6.3E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS26825 2c46090a6f8f843301a3124cb456c18c 369 PIRSF PIRSF000390 1 369 1.5E-121 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THSYN_RS19225 621433ed7be5f6993daf8cbcf06257b7 116 Gene3D G3DSA:3.30.2310.20 8 99 1.4E-4 T 29-03-2018 THSYN_RS19225 621433ed7be5f6993daf8cbcf06257b7 116 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 7 98 2.4E-16 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS07390 f8b5b77e86e669044f819982fe968e0c 778 Pfam PF07793 Protein of unknown function (DUF1631) 13 759 5.7E-171 T 29-03-2018 IPR012434 Protein of unknown function DUF1631 THSYN_RS19365 00251530737b506a820247aba2a165bb 200 SUPERFAMILY SSF52980 3 157 3.38E-19 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS19365 00251530737b506a820247aba2a165bb 200 Pfam PF05685 Putative restriction endonuclease 20 172 1.2E-26 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS19365 00251530737b506a820247aba2a165bb 200 Gene3D G3DSA:3.90.1570.10 1 189 6.9E-38 T 29-03-2018 THSYN_RS17165 277c6213895bf6546f2ea3804739d39b 391 Pfam PF01420 Type I restriction modification DNA specificity domain 2 153 1.3E-18 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS17165 277c6213895bf6546f2ea3804739d39b 391 Pfam PF01420 Type I restriction modification DNA specificity domain 190 359 4.5E-12 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS17165 277c6213895bf6546f2ea3804739d39b 391 SUPERFAMILY SSF116734 3 182 3.6E-31 T 29-03-2018 THSYN_RS17165 277c6213895bf6546f2ea3804739d39b 391 Gene3D G3DSA:3.90.220.20 164 367 5.5E-22 T 29-03-2018 THSYN_RS17165 277c6213895bf6546f2ea3804739d39b 391 Gene3D G3DSA:3.90.220.20 2 163 7.2E-29 T 29-03-2018 THSYN_RS17165 277c6213895bf6546f2ea3804739d39b 391 SUPERFAMILY SSF116734 189 367 2.13E-23 T 29-03-2018 THSYN_RS05245 9e9a102a83ae0b22924414c8af24d2a5 392 Gene3D G3DSA:2.60.60.30 11 164 1.3E-28 T 29-03-2018 THSYN_RS05245 9e9a102a83ae0b22924414c8af24d2a5 392 Gene3D G3DSA:2.60.60.30 214 377 1.0E-25 T 29-03-2018 THSYN_RS05245 9e9a102a83ae0b22924414c8af24d2a5 392 PIRSF PIRSF037118 1 392 2.6E-123 T 29-03-2018 IPR017115 Tellurite resistance, TerA THSYN_RS05245 9e9a102a83ae0b22924414c8af24d2a5 392 Pfam PF02342 TerD domain 2 165 6.6E-26 T 29-03-2018 IPR003325 TerD domain GO:0006950 THSYN_RS26020 5d13b43c04e2e5bd7f173b5944de8c47 89 Pfam PF08797 HIRAN domain 9 62 2.4E-11 T 29-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 THSYN_RS13180 507d771dadcec412ba389062fc8deccb 168 Gene3D G3DSA:3.40.630.30 23 160 5.0E-14 T 29-03-2018 THSYN_RS13180 507d771dadcec412ba389062fc8deccb 168 SUPERFAMILY SSF55729 42 154 4.83E-11 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS23295 77377eed0f72f5dbbc167286a5ac1be5 94 SUPERFAMILY SSF52091 2 78 1.16E-5 T 29-03-2018 IPR002645 STAS domain THSYN_RS27820 32a119551ed9e9ad3c17210f5a7767ac 543 Gene3D G3DSA:3.40.50.1820 50 295 1.1E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS27820 32a119551ed9e9ad3c17210f5a7767ac 543 SUPERFAMILY SSF53474 55 282 1.14E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS27820 32a119551ed9e9ad3c17210f5a7767ac 543 Pfam PF12146 Serine aminopeptidase, S33 75 194 4.6E-13 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 THSYN_RS31350 54e7924b5c9b71e35b02fa43c9e73cbe 341 ProSitePatterns PS00746 NifH/frxC family signature 1. 128 140 - T 29-03-2018 IPR030655 NifH/chlL conserved site THSYN_RS31350 54e7924b5c9b71e35b02fa43c9e73cbe 341 ProSitePatterns PS00692 NifH/frxC family signature 2. 166 179 - T 29-03-2018 IPR030655 NifH/chlL conserved site THSYN_RS31350 54e7924b5c9b71e35b02fa43c9e73cbe 341 Gene3D G3DSA:3.40.50.300 42 293 6.4E-34 T 29-03-2018 THSYN_RS31350 54e7924b5c9b71e35b02fa43c9e73cbe 341 SUPERFAMILY SSF52540 43 286 8.9E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31350 54e7924b5c9b71e35b02fa43c9e73cbe 341 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 45 307 1.9E-93 T 29-03-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 THSYN_RS31350 54e7924b5c9b71e35b02fa43c9e73cbe 341 TIGRFAM TIGR02016 BchX: chlorophyllide reductase iron protein subunit X 44 330 5.8E-127 T 29-03-2018 IPR010246 Chlorophyllide reductase iron protein subunit X GO:0005524|GO:0015979|GO:0016628|GO:0030494|GO:0051539 THSYN_RS31350 54e7924b5c9b71e35b02fa43c9e73cbe 341 PRINTS PR00091 Nitrogenase component II signature 71 86 7.6E-27 T 29-03-2018 THSYN_RS31350 54e7924b5c9b71e35b02fa43c9e73cbe 341 PRINTS PR00091 Nitrogenase component II signature 165 180 7.6E-27 T 29-03-2018 THSYN_RS31350 54e7924b5c9b71e35b02fa43c9e73cbe 341 PRINTS PR00091 Nitrogenase component II signature 49 62 7.6E-27 T 29-03-2018 THSYN_RS31350 54e7924b5c9b71e35b02fa43c9e73cbe 341 PRINTS PR00091 Nitrogenase component II signature 126 140 7.6E-27 T 29-03-2018 THSYN_RS02930 2aca08d2c6e9a0030e729b0d8a8bed00 349 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 25 155 2.2E-42 T 29-03-2018 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019 THSYN_RS02930 2aca08d2c6e9a0030e729b0d8a8bed00 349 Pfam PF16169 Domain of unknown function (DUF4872) 167 339 2.6E-45 T 29-03-2018 IPR032369 Domain of unknown function DUF4872 THSYN_RS13845 13f6769774417783a20e04cd5a93a601 151 Gene3D G3DSA:1.10.260.40 68 142 2.0E-5 T 29-03-2018 THSYN_RS13845 13f6769774417783a20e04cd5a93a601 151 SUPERFAMILY SSF143100 1 64 3.14E-9 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS13845 13f6769774417783a20e04cd5a93a601 151 SUPERFAMILY SSF47413 77 138 4.78E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS13845 13f6769774417783a20e04cd5a93a601 151 Gene3D G3DSA:3.30.2390.10 3 67 1.2E-6 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS32675 685b7ced5e258b06f16950d3327b8079 152 PIRSF PIRSF012335 1 152 2.7E-65 T 29-03-2018 IPR016596 Protein of unknown function UCP012335 THSYN_RS32675 685b7ced5e258b06f16950d3327b8079 152 Pfam PF11008 Protein of unknown function (DUF2846) 15 126 2.2E-30 T 29-03-2018 IPR022548 Domain of unknown function DUF2846 THSYN_RS22855 7b3ec7e0b1a7fc97cc4a1a930ea8d38c 181 SUPERFAMILY SSF52200 2 112 7.85E-16 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS22855 7b3ec7e0b1a7fc97cc4a1a930ea8d38c 181 Gene3D G3DSA:3.40.50.10140 1 123 5.0E-17 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS22855 7b3ec7e0b1a7fc97cc4a1a930ea8d38c 181 Pfam PF13676 TIR domain 10 106 1.2E-18 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS30810 c581552afd92ee7d8c8f5c50d14b2ec9 448 SUPERFAMILY SSF52540 136 392 1.13E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30810 c581552afd92ee7d8c8f5c50d14b2ec9 448 Gene3D G3DSA:3.40.50.300 126 378 1.4E-27 T 29-03-2018 THSYN_RS30810 c581552afd92ee7d8c8f5c50d14b2ec9 448 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 141 225 1.0E-8 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THSYN_RS15515 2c5bce4c961f122e1693295698e5efba 1140 Pfam PF13699 Domain of unknown function (DUF4157) 228 304 1.6E-30 T 29-03-2018 IPR025295 Domain of unknown function DUF4157 THSYN_RS09735 74aadb0072cf0122f0b91487e0f78299 250 Gene3D G3DSA:3.40.190.10 114 210 1.2E-27 T 29-03-2018 THSYN_RS09735 74aadb0072cf0122f0b91487e0f78299 250 Pfam PF13531 Bacterial extracellular solute-binding protein 26 248 4.8E-42 T 29-03-2018 THSYN_RS09735 74aadb0072cf0122f0b91487e0f78299 250 Gene3D G3DSA:3.40.190.10 20 113 7.9E-11 T 29-03-2018 THSYN_RS09735 74aadb0072cf0122f0b91487e0f78299 250 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 30 247 9.3E-73 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 THSYN_RS09735 74aadb0072cf0122f0b91487e0f78299 250 SUPERFAMILY SSF53850 24 248 2.29E-55 T 29-03-2018 THSYN_RS09735 74aadb0072cf0122f0b91487e0f78299 250 PIRSF PIRSF004846 2 250 9.2E-46 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 THSYN_RS18980 65a572015f181125f47163f337a0bb96 377 Pfam PF03916 Polysulphide reductase, NrfD 42 327 1.2E-10 T 29-03-2018 IPR005614 NrfD family THSYN_RS18980 65a572015f181125f47163f337a0bb96 377 Gene3D G3DSA:1.20.1630.10 40 334 7.0E-36 T 29-03-2018 THSYN_RS03700 44b79da9cbb762878a2b157a0e603ab7 304 Pfam PF13175 AAA ATPase domain 6 56 4.2E-8 T 29-03-2018 THSYN_RS03700 44b79da9cbb762878a2b157a0e603ab7 304 Gene3D G3DSA:3.40.50.300 6 237 1.0E-9 T 29-03-2018 THSYN_RS03700 44b79da9cbb762878a2b157a0e603ab7 304 SUPERFAMILY SSF52540 6 66 1.06E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22835 a002e5494279a7f59c274094b0eeb61c 407 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 243 331 2.7E-6 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal THSYN_RS22835 a002e5494279a7f59c274094b0eeb61c 407 Pfam PF12323 Helix-turn-helix domain 1 47 5.1E-14 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain THSYN_RS22835 a002e5494279a7f59c274094b0eeb61c 407 Pfam PF07282 Putative transposase DNA-binding domain 304 372 2.7E-21 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal THSYN_RS22835 a002e5494279a7f59c274094b0eeb61c 407 Pfam PF01385 Probable transposase 173 275 2.8E-26 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 THSYN_RS13895 dedf64f584336eba79e881cbfe66f6d0 1156 Gene3D G3DSA:3.40.50.300 41 360 6.1E-6 T 29-03-2018 THSYN_RS13895 dedf64f584336eba79e881cbfe66f6d0 1156 SUPERFAMILY SSF52540 43 112 2.25E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13895 dedf64f584336eba79e881cbfe66f6d0 1156 SUPERFAMILY SSF52540 234 355 2.25E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24650 c3a784247719c73a4f75c193e8171f22 225 Pfam PF03840 Preprotein translocase SecG subunit 4 72 1.3E-19 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THSYN_RS24650 c3a784247719c73a4f75c193e8171f22 225 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 3.6E-33 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THSYN_RS24650 c3a784247719c73a4f75c193e8171f22 225 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 3.6E-33 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THSYN_RS24650 c3a784247719c73a4f75c193e8171f22 225 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 3.6E-33 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THSYN_RS24650 c3a784247719c73a4f75c193e8171f22 225 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 3.6E-33 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THSYN_RS24650 c3a784247719c73a4f75c193e8171f22 225 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 73 7.6E-25 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THSYN_RS05420 dc38d1655bd59c6da7014b3a5cef13b3 176 SUPERFAMILY SSF88874 1 170 2.09E-43 T 29-03-2018 THSYN_RS05420 dc38d1655bd59c6da7014b3a5cef13b3 176 Gene3D G3DSA:3.90.1340.10 1 68 1.6E-20 T 29-03-2018 IPR011083 Phage tail collar domain THSYN_RS05420 dc38d1655bd59c6da7014b3a5cef13b3 176 Pfam PF07484 Phage Tail Collar Domain 8 63 3.1E-25 T 29-03-2018 IPR011083 Phage tail collar domain THSYN_RS20745 029774dccc7c9336dbf29aae3bf96cbb 154 SMART SM00116 96 143 1.8E-7 T 29-03-2018 IPR000644 CBS domain THSYN_RS20745 029774dccc7c9336dbf29aae3bf96cbb 154 SMART SM00116 10 58 7.8E-8 T 29-03-2018 IPR000644 CBS domain THSYN_RS20745 029774dccc7c9336dbf29aae3bf96cbb 154 SUPERFAMILY SSF54631 1 143 9.1E-33 T 29-03-2018 THSYN_RS20745 029774dccc7c9336dbf29aae3bf96cbb 154 Gene3D G3DSA:3.10.580.10 1 153 6.9E-29 T 29-03-2018 THSYN_RS20745 029774dccc7c9336dbf29aae3bf96cbb 154 Pfam PF00571 CBS domain 89 142 2.3E-11 T 29-03-2018 IPR000644 CBS domain THSYN_RS20745 029774dccc7c9336dbf29aae3bf96cbb 154 Pfam PF00571 CBS domain 3 57 1.2E-10 T 29-03-2018 IPR000644 CBS domain THSYN_RS22455 d4d089db7212b1ff95534d4c8e417265 395 Pfam PF00487 Fatty acid desaturase 11 233 9.6E-15 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 THSYN_RS22455 d4d089db7212b1ff95534d4c8e417265 395 Pfam PF01610 Transposase 272 385 2.2E-11 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain THSYN_RS25055 898a3b074f7c3a555bacdf243402b71c 333 Pfam PF13439 Glycosyltransferase Family 4 95 154 1.5E-7 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS25055 898a3b074f7c3a555bacdf243402b71c 333 Pfam PF13692 Glycosyl transferases group 1 167 296 1.3E-14 T 29-03-2018 THSYN_RS25055 898a3b074f7c3a555bacdf243402b71c 333 SUPERFAMILY SSF53756 48 330 6.28E-47 T 29-03-2018 THSYN_RS25055 898a3b074f7c3a555bacdf243402b71c 333 Gene3D G3DSA:3.40.50.2000 114 331 5.8E-24 T 29-03-2018 THSYN_RS29135 699d1abe0bd53d8698ed7f994b706d15 197 Pfam PF09569 ScaI restriction endonuclease 3 194 2.3E-60 T 29-03-2018 IPR019069 Restriction endonuclease, type II, ScaI THSYN_RS25585 3a7d81ca67f1445c0e6d4727e2d7b099 687 Pfam PF07715 TonB-dependent Receptor Plug Domain 56 164 1.3E-17 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THSYN_RS25585 3a7d81ca67f1445c0e6d4727e2d7b099 687 Gene3D G3DSA:2.40.170.20 173 687 4.7E-41 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THSYN_RS25585 3a7d81ca67f1445c0e6d4727e2d7b099 687 Gene3D G3DSA:2.170.130.10 39 170 7.2E-22 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THSYN_RS25585 3a7d81ca67f1445c0e6d4727e2d7b099 687 Pfam PF00593 TonB dependent receptor 257 685 5.0E-24 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THSYN_RS25585 3a7d81ca67f1445c0e6d4727e2d7b099 687 SUPERFAMILY SSF56935 49 687 2.59E-74 T 29-03-2018 THSYN_RS12130 c09dc11ecc7130e7b1b4c82f807e7bef 197 SUPERFAMILY SSF49879 81 187 3.63E-15 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 THSYN_RS12130 c09dc11ecc7130e7b1b4c82f807e7bef 197 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 89 181 1.6E-9 T 29-03-2018 IPR032030 YscD, cytoplasmic domain THSYN_RS12130 c09dc11ecc7130e7b1b4c82f807e7bef 197 Gene3D G3DSA:2.60.200.20 82 181 1.5E-14 T 29-03-2018 THSYN_RS15125 3496026ee594c03046c8765edf0366f5 99 Pfam PF01909 Nucleotidyltransferase domain 15 76 1.2E-6 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS15125 3496026ee594c03046c8765edf0366f5 99 SUPERFAMILY SSF81301 2 99 1.01E-14 T 29-03-2018 THSYN_RS15125 3496026ee594c03046c8765edf0366f5 99 Gene3D G3DSA:3.30.460.10 1 98 6.2E-15 T 29-03-2018 THSYN_RS13015 ea4c8c6cc1303c4bb034946e8be55caf 759 Pfam PF00593 TonB dependent receptor 257 757 2.5E-35 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THSYN_RS13015 ea4c8c6cc1303c4bb034946e8be55caf 759 SUPERFAMILY SSF56935 28 759 5.86E-71 T 29-03-2018 THSYN_RS13015 ea4c8c6cc1303c4bb034946e8be55caf 759 Gene3D G3DSA:2.40.170.20 179 759 2.4E-56 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THSYN_RS24280 3fdfe283a6d9bb67297fae047fe308c7 193 Pfam PF00196 Bacterial regulatory proteins, luxR family 123 178 1.2E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS24280 3fdfe283a6d9bb67297fae047fe308c7 193 Gene3D G3DSA:3.40.50.2300 1 114 9.7E-23 T 29-03-2018 THSYN_RS24280 3fdfe283a6d9bb67297fae047fe308c7 193 SUPERFAMILY SSF52172 2 109 6.97E-24 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS24280 3fdfe283a6d9bb67297fae047fe308c7 193 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 166 1.1E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS24280 3fdfe283a6d9bb67297fae047fe308c7 193 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 124 138 1.1E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS24280 3fdfe283a6d9bb67297fae047fe308c7 193 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 154 1.1E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS24280 3fdfe283a6d9bb67297fae047fe308c7 193 Gene3D G3DSA:1.10.10.10 115 191 2.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS24280 3fdfe283a6d9bb67297fae047fe308c7 193 SMART SM00421 121 178 7.8E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THSYN_RS24280 3fdfe283a6d9bb67297fae047fe308c7 193 SMART SM00448 1 97 3.6E-10 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS24280 3fdfe283a6d9bb67297fae047fe308c7 193 Pfam PF00072 Response regulator receiver domain 6 98 8.5E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS24280 3fdfe283a6d9bb67297fae047fe308c7 193 SUPERFAMILY SSF46894 118 184 1.09E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS29550 723cd062ed944eb4619b7120882195fb 130 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 38 102 2.9E-6 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS29550 723cd062ed944eb4619b7120882195fb 130 Gene3D G3DSA:1.10.150.130 21 128 7.1E-11 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS29550 723cd062ed944eb4619b7120882195fb 130 SUPERFAMILY SSF47823 32 102 3.92E-11 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal THSYN_RS20430 b68b3fb621dd287e53e9ea340102e72c 69 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 3 42 1.3E-9 T 29-03-2018 IPR022453 Zinc finger, MqsA-type THSYN_RS29965 f17464fc5c68bba9e1ddb6c6d7cfddf8 62 PIRSF PIRSF037225 1 62 1.7E-23 T 29-03-2018 IPR017143 Uncharacterised conserved protein UCP037225 THSYN_RS29965 f17464fc5c68bba9e1ddb6c6d7cfddf8 62 Pfam PF14255 Cysteine-rich CPXCG 7 54 3.2E-23 T 29-03-2018 IPR025990 Cysteine-rich CPXCG protein THSYN_RS29800 781c633de1298788147cbf6df551f082 203 SUPERFAMILY SSF140478 26 183 1.03E-52 T 29-03-2018 IPR023353 LemA-like domain THSYN_RS29800 781c633de1298788147cbf6df551f082 203 Gene3D G3DSA:1.20.1440.20 14 196 3.0E-54 T 29-03-2018 THSYN_RS29800 781c633de1298788147cbf6df551f082 203 Pfam PF04011 LemA family 10 196 1.4E-63 T 29-03-2018 IPR007156 LemA THSYN_RS26330 5d9e50d7b913972f5ab092d17067d32d 320 Gene3D G3DSA:3.60.15.10 43 292 1.8E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS26330 5d9e50d7b913972f5ab092d17067d32d 320 SUPERFAMILY SSF56281 89 283 8.12E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS26330 5d9e50d7b913972f5ab092d17067d32d 320 Pfam PF12706 Beta-lactamase superfamily domain 89 221 5.1E-8 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS14435 a77bc7b003f702ba3d90f6f47dfb04f5 143 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 23 136 1.9E-15 T 29-03-2018 IPR012912 Plasmid pRiA4b, Orf3 THSYN_RS14435 a77bc7b003f702ba3d90f6f47dfb04f5 143 Gene3D G3DSA:3.10.290.30 1 140 3.2E-22 T 29-03-2018 IPR024047 Protein MM3350-like domain THSYN_RS14435 a77bc7b003f702ba3d90f6f47dfb04f5 143 SUPERFAMILY SSF159941 1 139 5.75E-22 T 29-03-2018 IPR024047 Protein MM3350-like domain THSYN_RS20595 13d556dc761e7aae1f2d48cf88776640 424 SUPERFAMILY SSF54106 55 103 7.59E-7 T 29-03-2018 IPR018392 LysM domain THSYN_RS20595 13d556dc761e7aae1f2d48cf88776640 424 Pfam PF01476 LysM domain 57 103 8.1E-12 T 29-03-2018 IPR018392 LysM domain THSYN_RS20595 13d556dc761e7aae1f2d48cf88776640 424 Gene3D G3DSA:3.10.350.10 53 103 1.5E-15 T 29-03-2018 THSYN_RS20595 13d556dc761e7aae1f2d48cf88776640 424 SMART SM00257 56 104 3.9E-5 T 29-03-2018 IPR018392 LysM domain THSYN_RS20495 e63ac56e756086fa551ee5b0c6af976a 188 Pfam PF03734 L,D-transpeptidase catalytic domain 56 186 6.3E-17 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 THSYN_RS20495 e63ac56e756086fa551ee5b0c6af976a 188 SUPERFAMILY SSF141523 55 187 6.41E-21 T 29-03-2018 THSYN_RS20495 e63ac56e756086fa551ee5b0c6af976a 188 Gene3D G3DSA:2.40.440.10 54 187 3.4E-21 T 29-03-2018 THSYN_RS32620 d97215af10cf91e0984c7cec0c90e93f 137 Gene3D G3DSA:3.40.190.10 1 85 1.7E-9 T 29-03-2018 THSYN_RS32620 d97215af10cf91e0984c7cec0c90e93f 137 SUPERFAMILY SSF53850 2 122 3.22E-10 T 29-03-2018 THSYN_RS32620 d97215af10cf91e0984c7cec0c90e93f 137 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 2 114 7.8E-7 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THSYN_RS07825 f3762bb3710bf15ac03d8be0a7c2d979 178 SUPERFAMILY SSF46955 6 80 9.89E-14 T 29-03-2018 IPR009061 Putative DNA-binding domain THSYN_RS07825 f3762bb3710bf15ac03d8be0a7c2d979 178 SMART SM00422 5 73 4.3E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THSYN_RS07825 f3762bb3710bf15ac03d8be0a7c2d979 178 Gene3D G3DSA:1.10.1660.10 1 176 1.1E-15 T 29-03-2018 THSYN_RS07825 f3762bb3710bf15ac03d8be0a7c2d979 178 Pfam PF13411 MerR HTH family regulatory protein 7 71 2.2E-10 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THSYN_RS30890 a22c5acf2099c4da4b7014498591b131 60 Pfam PF13490 Putative zinc-finger 6 39 3.1E-7 T 29-03-2018 IPR027383 Putative zinc-finger THSYN_RS27825 8398de6ecb0c267e1118cc85eec20f58 227 Gene3D G3DSA:3.20.80.10 42 211 6.1E-5 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain THSYN_RS27825 8398de6ecb0c267e1118cc85eec20f58 227 Pfam PF04832 SOUL heme-binding protein 29 207 1.9E-41 T 29-03-2018 IPR006917 SOUL haem-binding protein THSYN_RS27825 8398de6ecb0c267e1118cc85eec20f58 227 SUPERFAMILY SSF55136 21 208 1.5E-46 T 29-03-2018 THSYN_RS02420 6805bda3aefc2206b012cb9728383c46 167 Pfam PF00436 Single-strand binding protein family 7 112 2.2E-40 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 THSYN_RS02420 6805bda3aefc2206b012cb9728383c46 167 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 6 167 3.3E-51 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 THSYN_RS02420 6805bda3aefc2206b012cb9728383c46 167 Gene3D G3DSA:2.40.50.140 2 120 8.1E-44 T 29-03-2018 THSYN_RS02420 6805bda3aefc2206b012cb9728383c46 167 Hamap MF_00984 Single-stranded DNA-binding protein. 7 119 36.952 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 THSYN_RS02420 6805bda3aefc2206b012cb9728383c46 167 SUPERFAMILY SSF50249 7 167 1.23E-55 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS16785 2f1310a99b73ed0f4698f2faaed82183 90 Pfam PF14076 Domain of unknown function (DUF4258) 18 88 5.9E-11 T 29-03-2018 IPR025354 Protein of unknown function DUF4258 THSYN_RS25850 3c05c1c0d2386c7d181f10b3346a3ecc 272 Gene3D G3DSA:3.90.1570.10 13 178 2.4E-10 T 29-03-2018 THSYN_RS25850 3c05c1c0d2386c7d181f10b3346a3ecc 272 Pfam PF05685 Putative restriction endonuclease 19 161 9.2E-11 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS25850 3c05c1c0d2386c7d181f10b3346a3ecc 272 SUPERFAMILY SSF52980 19 169 1.29E-14 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS06505 afbd092bbb2ce9a918b3ea811d468136 348 SUPERFAMILY SSF103025 36 262 5.02E-61 T 29-03-2018 THSYN_RS06505 afbd092bbb2ce9a918b3ea811d468136 348 SUPERFAMILY SSF101790 264 343 2.03E-9 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain THSYN_RS06505 afbd092bbb2ce9a918b3ea811d468136 348 Pfam PF01571 Aminomethyltransferase folate-binding domain 37 152 6.1E-10 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal THSYN_RS06505 afbd092bbb2ce9a918b3ea811d468136 348 Gene3D G3DSA:3.30.70.1400 45 259 6.1E-27 T 29-03-2018 THSYN_RS06505 afbd092bbb2ce9a918b3ea811d468136 348 PIRSF PIRSF006487 191 301 130.0 T 29-03-2018 THSYN_RS06505 afbd092bbb2ce9a918b3ea811d468136 348 PIRSF PIRSF006487 32 164 8.6E-9 T 29-03-2018 THSYN_RS06505 afbd092bbb2ce9a918b3ea811d468136 348 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 207 270 2.2E-27 T 29-03-2018 IPR017703 YgfZ/GcvT conserved site THSYN_RS00500 78f8673635c9ebebc87ed3b78ff54aef 76 Pfam PF00582 Universal stress protein family 2 43 2.0E-6 T 29-03-2018 IPR006016 UspA GO:0006950 THSYN_RS00500 78f8673635c9ebebc87ed3b78ff54aef 76 Gene3D G3DSA:3.40.50.620 1 66 1.8E-9 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS00500 78f8673635c9ebebc87ed3b78ff54aef 76 SUPERFAMILY SSF52402 1 50 5.78E-8 T 29-03-2018 THSYN_RS22780 3436d26ee8323f5ad1ccd8e7851458ae 382 Pfam PF13439 Glycosyltransferase Family 4 14 184 1.4E-10 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS22780 3436d26ee8323f5ad1ccd8e7851458ae 382 Pfam PF00534 Glycosyl transferases group 1 205 355 2.6E-23 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS22780 3436d26ee8323f5ad1ccd8e7851458ae 382 Gene3D G3DSA:3.40.50.2000 174 362 2.0E-35 T 29-03-2018 THSYN_RS22780 3436d26ee8323f5ad1ccd8e7851458ae 382 Gene3D G3DSA:3.40.50.2000 1 173 5.2E-9 T 29-03-2018 THSYN_RS22780 3436d26ee8323f5ad1ccd8e7851458ae 382 SUPERFAMILY SSF53756 1 357 1.62E-55 T 29-03-2018 THSYN_RS00365 69f3a50da8dc60bc355ab68fad475c29 383 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 16 383 5.7E-150 T 29-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 THSYN_RS00365 69f3a50da8dc60bc355ab68fad475c29 383 Gene3D G3DSA:1.10.580.10 23 363 1.5E-76 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain THSYN_RS00365 69f3a50da8dc60bc355ab68fad475c29 383 PIRSF PIRSF001369 9 383 4.4E-105 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type THSYN_RS00365 69f3a50da8dc60bc355ab68fad475c29 383 Pfam PF00285 Citrate synthase, C-terminal domain 17 365 2.1E-107 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS00365 69f3a50da8dc60bc355ab68fad475c29 383 PRINTS PR00143 Citrate synthase signature 184 199 7.5E-33 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS00365 69f3a50da8dc60bc355ab68fad475c29 383 PRINTS PR00143 Citrate synthase signature 206 234 7.5E-33 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS00365 69f3a50da8dc60bc355ab68fad475c29 383 PRINTS PR00143 Citrate synthase signature 316 332 7.5E-33 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS00365 69f3a50da8dc60bc355ab68fad475c29 383 PRINTS PR00143 Citrate synthase signature 259 279 7.5E-33 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS00365 69f3a50da8dc60bc355ab68fad475c29 383 PRINTS PR00143 Citrate synthase signature 336 350 7.5E-33 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS00365 69f3a50da8dc60bc355ab68fad475c29 383 SUPERFAMILY SSF48256 16 383 1.28E-116 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 THSYN_RS00365 69f3a50da8dc60bc355ab68fad475c29 383 ProSitePatterns PS00480 Citrate synthase signature. 266 278 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 THSYN_RS12365 24fb3eade65848a8b53aee2623f94b82 428 SUPERFAMILY SSF51695 77 420 9.42E-58 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 THSYN_RS12365 24fb3eade65848a8b53aee2623f94b82 428 Gene3D G3DSA:3.20.20.190 59 428 6.5E-47 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 THSYN_RS12365 24fb3eade65848a8b53aee2623f94b82 428 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 79 416 2.7E-19 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 THSYN_RS14690 b02686267dd5505e4ca8b392b4a3e51b 112 Pfam PF03334 Na+/H+ antiporter subunit 9 89 3.0E-29 T 29-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 THSYN_RS14690 b02686267dd5505e4ca8b392b4a3e51b 112 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 8 95 2.7E-29 T 29-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 THSYN_RS32740 6d0b030e403e270b3bc1162e66957e5c 253 Gene3D G3DSA:1.20.5.50 111 187 4.9E-4 T 29-03-2018 THSYN_RS04825 d230cfc37522d694c960fc784574852c 131 Pfam PF07238 PilZ domain 9 95 6.0E-7 T 29-03-2018 IPR009875 PilZ domain GO:0035438 THSYN_RS04825 d230cfc37522d694c960fc784574852c 131 SUPERFAMILY SSF141371 2 101 3.34E-7 T 29-03-2018 THSYN_RS04825 d230cfc37522d694c960fc784574852c 131 Gene3D G3DSA:2.40.10.220 8 105 4.5E-9 T 29-03-2018 THSYN_RS30650 3a11e855e3e8757cdb93abc51445fcf7 101 Gene3D G3DSA:3.30.565.10 2 100 8.5E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS30650 3a11e855e3e8757cdb93abc51445fcf7 101 Pfam PF13581 Histidine kinase-like ATPase domain 6 97 4.0E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS30650 3a11e855e3e8757cdb93abc51445fcf7 101 SUPERFAMILY SSF55874 4 93 5.86E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS02405 908605bdb9192b884e5381d760b4549e 115 Gene3D G3DSA:1.10.1660.10 14 112 1.8E-12 T 29-03-2018 THSYN_RS02405 908605bdb9192b884e5381d760b4549e 115 Pfam PF13591 MerR HTH family regulatory protein 20 103 2.7E-19 T 29-03-2018 THSYN_RS02235 33ea6b96238da2131ef0a7f39e46447c 424 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 327 412 6.1E-21 T 29-03-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain THSYN_RS02235 33ea6b96238da2131ef0a7f39e46447c 424 Pfam PF04326 Putative DNA-binding domain 14 127 1.8E-17 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 THSYN_RS31655 e30660580e51eebcb129176cc9bd4437 166 TIGRFAM TIGR03054 photo_alph_chp1: putative photosynthetic complex assembly protein 13 145 1.3E-31 T 29-03-2018 IPR017495 Putative photosynthetic complex assembly protein THSYN_RS31535 9b38bca9111a910a2982e2411bf5e43d 682 SUPERFAMILY SSF53300 256 385 2.23E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS31535 9b38bca9111a910a2982e2411bf5e43d 682 Pfam PF13519 von Willebrand factor type A domain 258 379 9.6E-7 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS31535 9b38bca9111a910a2982e2411bf5e43d 682 Gene3D G3DSA:3.40.50.410 253 648 2.2E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS30240 e816dc5e2e759f168ea9c0aadf96e279 544 Pfam PF06074 Protein of unknown function (DUF935) 14 538 5.2E-154 T 29-03-2018 IPR009279 Protein of unknown function DUF935 THSYN_RS03775 82debed924762f0976ac7cb6d7194a9e 371 SUPERFAMILY SSF52540 4 49 1.53E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03775 82debed924762f0976ac7cb6d7194a9e 371 SUPERFAMILY SSF52540 202 302 1.53E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03775 82debed924762f0976ac7cb6d7194a9e 371 Pfam PF13175 AAA ATPase domain 229 301 4.4E-11 T 29-03-2018 THSYN_RS03775 82debed924762f0976ac7cb6d7194a9e 371 Gene3D G3DSA:3.40.50.300 245 328 1.1E-7 T 29-03-2018 THSYN_RS03775 82debed924762f0976ac7cb6d7194a9e 371 PIRSF PIRSF034888 1 370 2.5E-50 T 29-03-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 THSYN_RS03775 82debed924762f0976ac7cb6d7194a9e 371 Pfam PF12476 Protein of unknown function (DUF3696) 320 364 5.7E-8 T 29-03-2018 IPR022532 Domain of unknown function DUF3696, C-terminal THSYN_RS03775 82debed924762f0976ac7cb6d7194a9e 371 Gene3D G3DSA:3.40.50.300 1 222 2.9E-9 T 29-03-2018 THSYN_RS23030 27a519bb29306fee92060741bbad0f5c 214 SUPERFAMILY SSF52200 1 107 3.14E-10 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS23030 27a519bb29306fee92060741bbad0f5c 214 Gene3D G3DSA:3.40.50.10140 1 128 4.0E-13 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS23030 27a519bb29306fee92060741bbad0f5c 214 Pfam PF13676 TIR domain 1 107 4.4E-13 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS14485 ca9a98b02bd0da43262ab66e30064664 239 SUPERFAMILY SSF56214 124 214 2.79E-15 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 THSYN_RS14485 ca9a98b02bd0da43262ab66e30064664 239 Gene3D G3DSA:3.90.470.20 136 226 2.1E-9 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 THSYN_RS14485 ca9a98b02bd0da43262ab66e30064664 239 SUPERFAMILY SSF56214 28 116 1.62E-12 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 THSYN_RS14485 ca9a98b02bd0da43262ab66e30064664 239 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 125 186 2.5E-9 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 THSYN_RS14485 ca9a98b02bd0da43262ab66e30064664 239 Gene3D G3DSA:3.90.470.20 22 135 7.9E-17 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 THSYN_RS16120 cd059182193b410c5cc3dc817797eed8 227 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 12 211 6.3E-35 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 THSYN_RS16120 cd059182193b410c5cc3dc817797eed8 227 Pfam PF01914 MarC family integral membrane protein 10 214 1.3E-38 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 THSYN_RS31915 96de1c80a39e56244ddce16da52a5dfa 595 Gene3D G3DSA:3.40.50.10140 452 580 1.2E-11 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS31915 96de1c80a39e56244ddce16da52a5dfa 595 Pfam PF00656 Caspase domain 60 157 1.4E-5 T 29-03-2018 THSYN_RS31915 96de1c80a39e56244ddce16da52a5dfa 595 SUPERFAMILY SSF52200 460 559 4.32E-12 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS31915 96de1c80a39e56244ddce16da52a5dfa 595 SUPERFAMILY SSF52129 57 191 4.71E-5 T 29-03-2018 IPR029030 Caspase-like domain THSYN_RS31915 96de1c80a39e56244ddce16da52a5dfa 595 Gene3D G3DSA:3.40.50.1460 1 227 4.6E-21 T 29-03-2018 THSYN_RS31915 96de1c80a39e56244ddce16da52a5dfa 595 Pfam PF13676 TIR domain 463 558 8.0E-13 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS22540 fc2546edf4c89b3c1f3c84986b16c245 205 SUPERFAMILY SSF52540 3 189 1.47E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22540 fc2546edf4c89b3c1f3c84986b16c245 205 SMART SM00382 26 195 2.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS22540 fc2546edf4c89b3c1f3c84986b16c245 205 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 2 201 8.1E-67 T 29-03-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 THSYN_RS22540 fc2546edf4c89b3c1f3c84986b16c245 205 Pfam PF00005 ABC transporter 20 158 1.0E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS22540 fc2546edf4c89b3c1f3c84986b16c245 205 Gene3D G3DSA:3.40.50.300 1 197 1.5E-38 T 29-03-2018 THSYN_RS22540 fc2546edf4c89b3c1f3c84986b16c245 205 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS26155 d72b3f416b14e371ea85a65bbd7e646d 117 Gene3D G3DSA:4.10.490.10 41 115 3.2E-22 T 29-03-2018 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 THSYN_RS26155 d72b3f416b14e371ea85a65bbd7e646d 117 Pfam PF01355 High potential iron-sulfur protein 45 113 4.0E-21 T 29-03-2018 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 THSYN_RS26155 d72b3f416b14e371ea85a65bbd7e646d 117 SUPERFAMILY SSF57652 38 116 2.49E-23 T 29-03-2018 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 THSYN_RS28590 830cc8aa447cc4e67f1db6a924eacffa 444 SUPERFAMILY SSF56672 40 346 4.5E-53 T 29-03-2018 THSYN_RS28590 830cc8aa447cc4e67f1db6a924eacffa 444 Gene3D G3DSA:3.30.70.270 100 315 6.9E-29 T 29-03-2018 THSYN_RS28590 830cc8aa447cc4e67f1db6a924eacffa 444 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 86 315 3.0E-40 T 29-03-2018 IPR000477 Reverse transcriptase domain THSYN_RS28590 830cc8aa447cc4e67f1db6a924eacffa 444 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 42 401 6.0E-99 T 29-03-2018 IPR030931 Group II intron reverse transcriptase/maturase THSYN_RS23710 d5ee9ee7f9d3e4365c4df25314f15cc7 162 Gene3D G3DSA:3.40.1350.10 15 142 4.8E-25 T 29-03-2018 THSYN_RS23710 d5ee9ee7f9d3e4365c4df25314f15cc7 162 SUPERFAMILY SSF52980 28 139 2.68E-15 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS23710 d5ee9ee7f9d3e4365c4df25314f15cc7 162 Pfam PF04471 Restriction endonuclease 22 137 1.0E-30 T 29-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 THSYN_RS01330 89c4cd5bd1ba8c1262c683601ea5b7c6 491 PRINTS PR00410 Phenol hydroxylase reductase family signature 356 365 4.8E-9 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THSYN_RS01330 89c4cd5bd1ba8c1262c683601ea5b7c6 491 PRINTS PR00410 Phenol hydroxylase reductase family signature 372 391 4.8E-9 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THSYN_RS01330 89c4cd5bd1ba8c1262c683601ea5b7c6 491 PRINTS PR00410 Phenol hydroxylase reductase family signature 297 309 4.8E-9 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THSYN_RS01330 89c4cd5bd1ba8c1262c683601ea5b7c6 491 PRINTS PR00410 Phenol hydroxylase reductase family signature 459 467 4.8E-9 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THSYN_RS01330 89c4cd5bd1ba8c1262c683601ea5b7c6 491 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 202 210 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THSYN_RS01330 89c4cd5bd1ba8c1262c683601ea5b7c6 491 SUPERFAMILY SSF54292 161 254 2.75E-24 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS01330 89c4cd5bd1ba8c1262c683601ea5b7c6 491 Gene3D G3DSA:2.40.30.10 265 360 4.7E-12 T 29-03-2018 THSYN_RS01330 89c4cd5bd1ba8c1262c683601ea5b7c6 491 SUPERFAMILY SSF63380 271 362 1.4E-13 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THSYN_RS01330 89c4cd5bd1ba8c1262c683601ea5b7c6 491 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 181 244 1.3E-11 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS01330 89c4cd5bd1ba8c1262c683601ea5b7c6 491 Gene3D G3DSA:3.10.20.30 148 264 4.1E-21 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS01330 89c4cd5bd1ba8c1262c683601ea5b7c6 491 Gene3D G3DSA:3.40.50.80 361 490 4.3E-9 T 29-03-2018 THSYN_RS01330 89c4cd5bd1ba8c1262c683601ea5b7c6 491 SUPERFAMILY SSF52343 352 487 2.1E-17 T 29-03-2018 THSYN_RS00735 7dde61a929965a08abe50cd146664f59 198 SMART SM00478 6 163 4.2E-27 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THSYN_RS00735 7dde61a929965a08abe50cd146664f59 198 Gene3D G3DSA:1.10.1670.10 94 197 5.8E-25 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 THSYN_RS00735 7dde61a929965a08abe50cd146664f59 198 SUPERFAMILY SSF48150 1 184 4.08E-45 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 THSYN_RS00735 7dde61a929965a08abe50cd146664f59 198 PIRSF PIRSF001435 1 189 1.1E-62 T 29-03-2018 THSYN_RS00735 7dde61a929965a08abe50cd146664f59 198 Gene3D G3DSA:1.10.340.30 1 93 1.8E-21 T 29-03-2018 THSYN_RS00735 7dde61a929965a08abe50cd146664f59 198 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 2 140 5.1E-18 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THSYN_RS04780 194a5f5c620a976c9a0367a17bc7aebc 349 PIRSF PIRSF015268 3 344 3.7E-146 T 29-03-2018 IPR011204 Virulence protein RhuM-like THSYN_RS04780 194a5f5c620a976c9a0367a17bc7aebc 349 Gene3D G3DSA:1.10.10.10 7 338 0.003 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS04780 194a5f5c620a976c9a0367a17bc7aebc 349 Pfam PF13310 Virulence protein RhuM family 67 314 1.5E-110 T 29-03-2018 IPR011204 Virulence protein RhuM-like THSYN_RS15695 ccd87953aeb1818b560b3caef6560570 202 Pfam PF07589 PEP-CTERM motif 177 200 6.3E-5 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS15695 ccd87953aeb1818b560b3caef6560570 202 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 178 202 2.8E-5 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS26665 eee9c05f1a5c0bb83d3e94e13d2b983a 326 Gene3D G3DSA:3.60.15.10 2 276 1.8E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS26665 eee9c05f1a5c0bb83d3e94e13d2b983a 326 SUPERFAMILY SSF56281 6 274 8.12E-52 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS26665 eee9c05f1a5c0bb83d3e94e13d2b983a 326 SMART SM00849 25 230 2.7E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS26665 eee9c05f1a5c0bb83d3e94e13d2b983a 326 Pfam PF00753 Metallo-beta-lactamase superfamily 26 230 2.6E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS26960 ec69e450e08a3d40c7c66ad92d686fce 358 Pfam PF03116 NQR2, RnfD, RnfE family 7 344 1.3E-106 T 29-03-2018 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 THSYN_RS26960 ec69e450e08a3d40c7c66ad92d686fce 358 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 5 346 26.926 T 29-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 THSYN_RS26960 ec69e450e08a3d40c7c66ad92d686fce 358 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 10 345 9.3E-117 T 29-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 THSYN_RS12670 aa97f4d443f60da69145b985f736de54 83 Pfam PF08808 RES domain 26 76 6.8E-9 T 29-03-2018 IPR014914 RES domain THSYN_RS32455 766927b9f99299e02ab9c4a3f852e884 317 Pfam PF03186 CobD/Cbib protein 11 297 4.0E-86 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 THSYN_RS32455 766927b9f99299e02ab9c4a3f852e884 317 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 317 81.824 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 THSYN_RS32455 766927b9f99299e02ab9c4a3f852e884 317 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 9 263 2.5E-60 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 THSYN_RS27400 3b2656e576126fcff6e2eec8e1759b97 76 SUPERFAMILY SSF143120 3 41 1.44E-6 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS27400 3b2656e576126fcff6e2eec8e1759b97 76 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 40 1.6E-6 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS27400 3b2656e576126fcff6e2eec8e1759b97 76 Gene3D G3DSA:3.40.1620.10 3 39 5.6E-9 T 29-03-2018 THSYN_RS13170 1f29f3ff4bf9f1d91374a1929184bc5b 472 Gene3D G3DSA:1.10.3720.10 4 458 4.2E-31 T 29-03-2018 THSYN_RS13170 1f29f3ff4bf9f1d91374a1929184bc5b 472 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 265 469 1.5E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS13170 1f29f3ff4bf9f1d91374a1929184bc5b 472 SUPERFAMILY SSF161098 249 447 6.8E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS19280 318ac964efbfc92b24382c73eef8d3fb 123 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 96 1.6E-14 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THSYN_RS19280 318ac964efbfc92b24382c73eef8d3fb 123 SUPERFAMILY SSF53146 1 122 5.89E-23 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THSYN_RS19280 318ac964efbfc92b24382c73eef8d3fb 123 Gene3D G3DSA:3.30.420.130 1 122 4.5E-18 T 29-03-2018 THSYN_RS12610 9737ff904df150d835a2a09e76735cf8 333 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 196 320 3.5E-14 T 29-03-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal THSYN_RS15285 6a9b5f8c2f7b853881a75cd809852eb4 265 SUPERFAMILY SSF52540 20 244 4.93E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15285 6a9b5f8c2f7b853881a75cd809852eb4 265 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS15285 6a9b5f8c2f7b853881a75cd809852eb4 265 Pfam PF00005 ABC transporter 40 188 1.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS15285 6a9b5f8c2f7b853881a75cd809852eb4 265 SMART SM00382 49 237 3.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS15285 6a9b5f8c2f7b853881a75cd809852eb4 265 Gene3D G3DSA:3.40.50.300 16 264 2.1E-60 T 29-03-2018 THSYN_RS31230 408be295ea1a0f52747dc4d2fddb026f 179 Gene3D G3DSA:1.20.950.20 1 178 4.9E-22 T 29-03-2018 THSYN_RS31230 408be295ea1a0f52747dc4d2fddb026f 179 SUPERFAMILY SSF81342 4 176 6.28E-25 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THSYN_RS31230 408be295ea1a0f52747dc4d2fddb026f 179 Pfam PF01292 Prokaryotic cytochrome b561 5 176 2.0E-19 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THSYN_RS05565 5e8cb42ccc987581c530b4af1f90d9c5 189 Pfam PF05685 Putative restriction endonuclease 12 172 3.3E-33 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS05565 5e8cb42ccc987581c530b4af1f90d9c5 189 Gene3D G3DSA:3.90.1570.10 2 188 6.1E-42 T 29-03-2018 THSYN_RS05565 5e8cb42ccc987581c530b4af1f90d9c5 189 SUPERFAMILY SSF52980 2 164 1.39E-24 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS05115 4e365085ebe592d1fcbb734eede4f965 269 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 110 2.6E-23 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 THSYN_RS05115 4e365085ebe592d1fcbb734eede4f965 269 Gene3D G3DSA:3.20.20.70 143 258 2.9E-20 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS05115 4e365085ebe592d1fcbb734eede4f965 269 Gene3D G3DSA:3.20.20.70 1 142 9.3E-41 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS05115 4e365085ebe592d1fcbb734eede4f965 269 SUPERFAMILY SSF51395 1 254 1.31E-61 T 29-03-2018 THSYN_RS32315 55e60f48cb6fc539022d228849bf4e96 218 SUPERFAMILY SSF55469 13 212 4.71E-51 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THSYN_RS32315 55e60f48cb6fc539022d228849bf4e96 218 Pfam PF00881 Nitroreductase family 17 181 1.8E-29 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 THSYN_RS32315 55e60f48cb6fc539022d228849bf4e96 218 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 5 206 2.6E-77 T 29-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 THSYN_RS32315 55e60f48cb6fc539022d228849bf4e96 218 Gene3D G3DSA:3.40.109.10 2 216 9.3E-44 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THSYN_RS13360 2561947b33db0f03c9d1a8231056afb4 268 Gene3D G3DSA:3.40.50.300 25 175 1.7E-23 T 29-03-2018 THSYN_RS13360 2561947b33db0f03c9d1a8231056afb4 268 SUPERFAMILY SSF52540 25 243 1.73E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13360 2561947b33db0f03c9d1a8231056afb4 268 Pfam PF07728 AAA domain (dynein-related subfamily) 35 169 3.4E-30 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THSYN_RS13360 2561947b33db0f03c9d1a8231056afb4 268 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 182 266 6.3E-31 T 29-03-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal THSYN_RS01970 5d6fdb494e0fbc857ee50e31bb0630ce 335 Gene3D G3DSA:3.90.25.10 176 334 1.9E-40 T 29-03-2018 THSYN_RS01970 5d6fdb494e0fbc857ee50e31bb0630ce 335 SUPERFAMILY SSF51735 1 333 3.42E-91 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS01970 5d6fdb494e0fbc857ee50e31bb0630ce 335 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 240 9.3E-56 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THSYN_RS01970 5d6fdb494e0fbc857ee50e31bb0630ce 335 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 5.1E-32 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 THSYN_RS01970 5d6fdb494e0fbc857ee50e31bb0630ce 335 PRINTS PR01713 Nucleotide sugar epimerase signature 295 312 5.1E-32 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 THSYN_RS01970 5d6fdb494e0fbc857ee50e31bb0630ce 335 PRINTS PR01713 Nucleotide sugar epimerase signature 256 271 5.1E-32 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 THSYN_RS01970 5d6fdb494e0fbc857ee50e31bb0630ce 335 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 5.1E-32 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 THSYN_RS01970 5d6fdb494e0fbc857ee50e31bb0630ce 335 Gene3D G3DSA:3.40.50.720 1 175 1.2E-32 T 29-03-2018 THSYN_RS31510 9e3abef9718250cae4f6f91577dae527 207 Pfam PF03729 Short repeat of unknown function (DUF308) 88 156 9.0E-8 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane THSYN_RS31510 9e3abef9718250cae4f6f91577dae527 207 Pfam PF03729 Short repeat of unknown function (DUF308) 30 100 5.6E-8 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane THSYN_RS02205 e45020aecda79e33b1a848d2535d28fe 266 Gene3D G3DSA:1.10.3810.10 82 259 4.0E-52 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 THSYN_RS02205 e45020aecda79e33b1a848d2535d28fe 266 SUPERFAMILY SSF53955 88 258 3.09E-58 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS02205 e45020aecda79e33b1a848d2535d28fe 266 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 36 260 38.033 T 29-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 THSYN_RS02205 e45020aecda79e33b1a848d2535d28fe 266 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 43 257 1.2E-70 T 29-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 THSYN_RS02205 e45020aecda79e33b1a848d2535d28fe 266 Pfam PF00912 Transglycosylase 91 253 5.0E-47 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 THSYN_RS22430 a855b1ba242f9d3f591ff2adc6cf5773 137 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 15 128 1.8E-42 T 29-03-2018 IPR026350 GxxExxY protein THSYN_RS22430 a855b1ba242f9d3f591ff2adc6cf5773 137 Pfam PF13366 PD-(D/E)XK nuclease superfamily 15 126 1.9E-38 T 29-03-2018 IPR026350 GxxExxY protein THSYN_RS22160 57e0724d4d95ed9bcf27a704d1b00093 99 SUPERFAMILY SSF81301 2 97 5.06E-14 T 29-03-2018 THSYN_RS22160 57e0724d4d95ed9bcf27a704d1b00093 99 Pfam PF01909 Nucleotidyltransferase domain 15 93 7.3E-8 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS22160 57e0724d4d95ed9bcf27a704d1b00093 99 Gene3D G3DSA:3.30.460.10 1 97 5.5E-14 T 29-03-2018 THSYN_RS27460 dabfa90d32e271a128680e9c62f3923e 351 Pfam PF06114 IrrE N-terminal-like domain 163 251 9.8E-12 T 29-03-2018 IPR010359 IrrE N-terminal-like domain THSYN_RS04335 ad811a151ad409e280dc496bf637cde8 254 SUPERFAMILY SSF52540 1 252 2.25E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04335 ad811a151ad409e280dc496bf637cde8 254 Gene3D G3DSA:3.40.50.300 2 254 7.6E-52 T 29-03-2018 THSYN_RS04335 ad811a151ad409e280dc496bf637cde8 254 Pfam PF13614 AAA domain 5 181 2.0E-36 T 29-03-2018 IPR025669 AAA domain THSYN_RS23820 146354a367a68ac11b8b52d7caa85041 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 3.1E-29 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P THSYN_RS23820 146354a367a68ac11b8b52d7caa85041 144 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 6.3E-44 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THSYN_RS23820 146354a367a68ac11b8b52d7caa85041 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 144 19.213 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 THSYN_RS23820 146354a367a68ac11b8b52d7caa85041 144 SUPERFAMILY SSF52080 4 143 1.01E-42 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P THSYN_RS23820 146354a367a68ac11b8b52d7caa85041 144 Gene3D G3DSA:3.100.10.10 41 144 4.7E-22 T 29-03-2018 THSYN_RS13350 ec4ae2bab0abdea8bd2ee177a5465f55 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.9E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS13350 ec4ae2bab0abdea8bd2ee177a5465f55 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.9E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS13350 ec4ae2bab0abdea8bd2ee177a5465f55 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.9E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS13350 ec4ae2bab0abdea8bd2ee177a5465f55 326 SUPERFAMILY SSF46785 2 83 1.28E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS13350 ec4ae2bab0abdea8bd2ee177a5465f55 326 Gene3D G3DSA:3.40.190.10 178 268 3.5E-21 T 29-03-2018 THSYN_RS13350 ec4ae2bab0abdea8bd2ee177a5465f55 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.2E-24 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS13350 ec4ae2bab0abdea8bd2ee177a5465f55 326 Gene3D G3DSA:1.10.10.10 1 88 8.5E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS13350 ec4ae2bab0abdea8bd2ee177a5465f55 326 SUPERFAMILY SSF53850 92 298 3.41E-48 T 29-03-2018 THSYN_RS13350 ec4ae2bab0abdea8bd2ee177a5465f55 326 Pfam PF03466 LysR substrate binding domain 91 293 5.6E-55 T 29-03-2018 IPR005119 LysR, substrate-binding THSYN_RS13350 ec4ae2bab0abdea8bd2ee177a5465f55 326 Gene3D G3DSA:3.40.190.10 89 177 3.1E-20 T 29-03-2018 THSYN_RS24415 e0811c4d27ae03c1d7c6f2f2f862b1d9 383 Pfam PF01807 CHC2 zinc finger 33 99 4.1E-9 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 THSYN_RS24415 e0811c4d27ae03c1d7c6f2f2f862b1d9 383 Gene3D G3DSA:3.90.1530.10 92 198 2.9E-10 T 29-03-2018 THSYN_RS24415 e0811c4d27ae03c1d7c6f2f2f862b1d9 383 Pfam PF02195 ParB-like nuclease domain 127 171 5.7E-6 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS24415 e0811c4d27ae03c1d7c6f2f2f862b1d9 383 Gene3D G3DSA:3.90.580.10 15 91 4.1E-12 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 THSYN_RS24415 e0811c4d27ae03c1d7c6f2f2f862b1d9 383 SMART SM00470 108 192 0.0022 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS24415 e0811c4d27ae03c1d7c6f2f2f862b1d9 383 SUPERFAMILY SSF57783 31 100 7.99E-11 T 29-03-2018 THSYN_RS24415 e0811c4d27ae03c1d7c6f2f2f862b1d9 383 SUPERFAMILY SSF110849 119 213 4.01E-11 T 29-03-2018 IPR003115 ParB/Sulfiredoxin THSYN_RS05155 951c207d42c526eb54070f6cb2b3aa8c 792 Pfam PF03968 OstA-like protein 100 190 7.6E-5 T 29-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal THSYN_RS05155 951c207d42c526eb54070f6cb2b3aa8c 792 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 40 771 19.44 T 29-03-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 THSYN_RS05155 951c207d42c526eb54070f6cb2b3aa8c 792 Pfam PF04453 Organic solvent tolerance protein 343 709 6.2E-80 T 29-03-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 THSYN_RS05155 951c207d42c526eb54070f6cb2b3aa8c 792 Gene3D G3DSA:2.60.450.10 90 245 1.5E-19 T 29-03-2018 THSYN_RS17450 b2e47c3d6915e935b4864a69d9d7a658 435 SUPERFAMILY SSF56935 30 430 3.75E-60 T 29-03-2018 THSYN_RS17450 b2e47c3d6915e935b4864a69d9d7a658 435 Gene3D G3DSA:2.40.160.60 30 435 1.8E-66 T 29-03-2018 THSYN_RS17450 b2e47c3d6915e935b4864a69d9d7a658 435 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 22 435 8.6E-54 T 29-03-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) THSYN_RS18165 8b3ac557929e2becaea38013524cbe4e 72 Gene3D G3DSA:1.10.10.10 6 65 3.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS18165 8b3ac557929e2becaea38013524cbe4e 72 SUPERFAMILY SSF46689 5 59 2.15E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS18165 8b3ac557929e2becaea38013524cbe4e 72 Pfam PF04255 Protein of unknown function (DUF433) 6 59 1.6E-16 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS06090 36794fbeceeeecddc5a2e0f39a38b852 838 Pfam PF02687 FtsX-like permease family 286 386 1.3E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THSYN_RS06090 36794fbeceeeecddc5a2e0f39a38b852 838 Pfam PF02687 FtsX-like permease family 735 829 1.5E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THSYN_RS06090 36794fbeceeeecddc5a2e0f39a38b852 838 Pfam PF12704 MacB-like periplasmic core domain 18 230 1.0E-6 T 29-03-2018 IPR025857 MacB-like periplasmic core domain THSYN_RS12880 095148e28a30a927b30e9cc5625b2a0b 212 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 50 57 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THSYN_RS12880 095148e28a30a927b30e9cc5625b2a0b 212 Gene3D G3DSA:3.40.1050.10 1 208 1.8E-55 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THSYN_RS12880 095148e28a30a927b30e9cc5625b2a0b 212 SUPERFAMILY SSF53056 3 203 7.19E-51 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THSYN_RS12880 095148e28a30a927b30e9cc5625b2a0b 212 Pfam PF00484 Carbonic anhydrase 45 198 7.9E-37 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THSYN_RS12880 095148e28a30a927b30e9cc5625b2a0b 212 SMART SM00947 38 203 1.8E-50 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THSYN_RS25505 1f5f1884ee52da926a5e24b6ff836040 149 Gene3D G3DSA:1.10.10.10 72 144 2.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25505 1f5f1884ee52da926a5e24b6ff836040 149 Pfam PF13776 Domain of unknown function (DUF4172) 2 50 6.5E-9 T 29-03-2018 IPR025230 Domain of unknown function DUF4172 THSYN_RS13165 d456e726da2f4b383b75cd76db9e922e 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 155 323 1.6E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS13165 d456e726da2f4b383b75cd76db9e922e 325 Gene3D G3DSA:1.10.3720.10 2 312 2.6E-30 T 29-03-2018 THSYN_RS13165 d456e726da2f4b383b75cd76db9e922e 325 SUPERFAMILY SSF161098 108 311 1.31E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS33090 37e566e0c2d87d84f4a798384d02b52c 335 Pfam PF00589 Phage integrase family 129 300 2.3E-34 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS33090 37e566e0c2d87d84f4a798384d02b52c 335 Gene3D G3DSA:1.10.150.130 12 125 1.2E-15 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS33090 37e566e0c2d87d84f4a798384d02b52c 335 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 18 100 5.5E-13 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS33090 37e566e0c2d87d84f4a798384d02b52c 335 SUPERFAMILY SSF56349 124 310 1.18E-45 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS33090 37e566e0c2d87d84f4a798384d02b52c 335 SUPERFAMILY SSF47823 17 100 4.51E-5 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal THSYN_RS33090 37e566e0c2d87d84f4a798384d02b52c 335 Gene3D G3DSA:1.10.443.10 128 310 9.0E-41 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS12475 07fd1e17cf1e00ac4dda88ce081e3559 530 SMART SM00382 275 410 7.8E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS12475 07fd1e17cf1e00ac4dda88ce081e3559 530 Gene3D G3DSA:1.10.8.60 408 512 3.6E-10 T 29-03-2018 THSYN_RS12475 07fd1e17cf1e00ac4dda88ce081e3559 530 SUPERFAMILY SSF52540 244 482 4.19E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12475 07fd1e17cf1e00ac4dda88ce081e3559 530 Gene3D G3DSA:3.40.50.300 246 406 4.6E-29 T 29-03-2018 THSYN_RS12475 07fd1e17cf1e00ac4dda88ce081e3559 530 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 279 407 6.9E-28 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS12475 07fd1e17cf1e00ac4dda88ce081e3559 530 SUPERFAMILY SSF52540 69 210 2.19E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12475 07fd1e17cf1e00ac4dda88ce081e3559 530 SUPERFAMILY SSF52540 16 38 2.19E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS12475 07fd1e17cf1e00ac4dda88ce081e3559 530 Gene3D G3DSA:3.40.50.300 27 243 0.01 T 29-03-2018 THSYN_RS29775 307c62db185bebd32fa3bbdfc893398b 449 SUPERFAMILY SSF55785 102 235 8.38E-25 T 29-03-2018 IPR000014 PAS domain THSYN_RS29775 307c62db185bebd32fa3bbdfc893398b 449 Gene3D G3DSA:3.30.565.10 307 446 2.0E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS29775 307c62db185bebd32fa3bbdfc893398b 449 SMART SM00091 117 183 1.2E-10 T 29-03-2018 IPR000014 PAS domain THSYN_RS29775 307c62db185bebd32fa3bbdfc893398b 449 SUPERFAMILY SSF55874 309 439 3.14E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS29775 307c62db185bebd32fa3bbdfc893398b 449 SMART SM00387 351 442 9.0E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS29775 307c62db185bebd32fa3bbdfc893398b 449 Gene3D G3DSA:3.30.450.20 85 265 2.5E-36 T 29-03-2018 THSYN_RS29775 307c62db185bebd32fa3bbdfc893398b 449 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 115 243 3.0E-21 T 29-03-2018 IPR000014 PAS domain THSYN_RS29775 307c62db185bebd32fa3bbdfc893398b 449 Pfam PF00989 PAS fold 117 234 7.1E-12 T 29-03-2018 IPR013767 PAS fold GO:0006355 THSYN_RS25815 b7ef9a9cd2a85cb97ade98bda9bf0166 89 SUPERFAMILY SSF47598 10 86 1.2E-20 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS25815 b7ef9a9cd2a85cb97ade98bda9bf0166 89 Pfam PF08681 Protein of unknown function (DUF1778) 12 88 2.6E-25 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 THSYN_RS25815 b7ef9a9cd2a85cb97ade98bda9bf0166 89 Gene3D G3DSA:1.10.1220.10 9 52 5.9E-16 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS25815 b7ef9a9cd2a85cb97ade98bda9bf0166 89 Gene3D G3DSA:1.20.890.30 57 89 1.4E-8 T 29-03-2018 THSYN_RS32530 9068fdaf7b602fcb9977d92f0085e37d 414 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 88 154 2.0E-18 T 29-03-2018 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal THSYN_RS32530 9068fdaf7b602fcb9977d92f0085e37d 414 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 163 306 4.4E-30 T 29-03-2018 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal THSYN_RS26390 e7caf745ffe492ac96444f7b6ac0f2c7 420 Gene3D G3DSA:3.60.15.10 1 408 3.4E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS26390 e7caf745ffe492ac96444f7b6ac0f2c7 420 SUPERFAMILY SSF56281 368 404 2.27E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS26390 e7caf745ffe492ac96444f7b6ac0f2c7 420 SUPERFAMILY SSF56281 9 297 2.27E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS26390 e7caf745ffe492ac96444f7b6ac0f2c7 420 Pfam PF12706 Beta-lactamase superfamily domain 60 195 3.7E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS26390 e7caf745ffe492ac96444f7b6ac0f2c7 420 SMART SM00849 2 199 2.1E-8 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS05025 5378a3a5f3570737aa8dc02c9bd0d475 157 Gene3D G3DSA:3.10.590.10 1 157 2.3E-61 T 29-03-2018 THSYN_RS05025 5378a3a5f3570737aa8dc02c9bd0d475 157 Pfam PF01878 EVE domain 2 152 1.7E-54 T 29-03-2018 IPR002740 EVE domain THSYN_RS05025 5378a3a5f3570737aa8dc02c9bd0d475 157 SUPERFAMILY SSF88697 1 153 1.42E-59 T 29-03-2018 IPR015947 PUA-like domain THSYN_RS19610 01e457a5f1c741383453ef6ba035d285 236 PIRSF PIRSF039137 1 236 1.2E-104 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 THSYN_RS19610 01e457a5f1c741383453ef6ba035d285 236 Pfam PF00005 ABC transporter 19 164 6.0E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS19610 01e457a5f1c741383453ef6ba035d285 236 SMART SM00382 28 206 4.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS19610 01e457a5f1c741383453ef6ba035d285 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS19610 01e457a5f1c741383453ef6ba035d285 236 SUPERFAMILY SSF52540 3 234 7.31E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS19610 01e457a5f1c741383453ef6ba035d285 236 Gene3D G3DSA:3.40.50.300 1 235 1.4E-57 T 29-03-2018 THSYN_RS11920 10fe129ac05d121c6967b24808705546 244 Gene3D G3DSA:1.20.5.1230 24 205 2.1E-5 T 29-03-2018 THSYN_RS25700 1107f460553855b2dc26defd1dd5047e 400 Gene3D G3DSA:3.40.50.410 114 331 8.9E-4 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS25700 1107f460553855b2dc26defd1dd5047e 400 SUPERFAMILY SSF53300 173 330 3.71E-5 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS20870 ce31c69e626c0a419598d45fb0de86ae 72 Pfam PF11127 Protein of unknown function (DUF2892) 7 65 6.0E-15 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 THSYN_RS01500 e63cc3281d40d0ea783e741990ff7a05 192 Pfam PF04972 BON domain 42 110 1.3E-11 T 29-03-2018 IPR007055 BON domain THSYN_RS01500 e63cc3281d40d0ea783e741990ff7a05 192 Pfam PF04972 BON domain 135 188 1.2E-9 T 29-03-2018 IPR007055 BON domain THSYN_RS31625 c58c58371c2515bad3a2af817222cdbc 56 SUPERFAMILY SSF88723 5 51 1.18E-12 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS31625 c58c58371c2515bad3a2af817222cdbc 56 Gene3D G3DSA:3.40.50.1010 1 53 1.3E-9 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS08995 bc71a304e4697d5f7a85a96cb821ab3a 194 Pfam PF05685 Putative restriction endonuclease 15 172 5.0E-27 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS08995 bc71a304e4697d5f7a85a96cb821ab3a 194 Gene3D G3DSA:3.90.1570.10 2 189 2.1E-39 T 29-03-2018 THSYN_RS08995 bc71a304e4697d5f7a85a96cb821ab3a 194 SUPERFAMILY SSF52980 2 161 9.12E-21 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS22935 b8c0b508e591c867035f620bf85c21b4 265 Pfam PF08808 RES domain 76 224 1.5E-26 T 29-03-2018 IPR014914 RES domain THSYN_RS22935 b8c0b508e591c867035f620bf85c21b4 265 SMART SM00953 85 222 8.8E-29 T 29-03-2018 IPR014914 RES domain THSYN_RS24850 8304039def5bda7f854b12bb2e925142 1117 SUPERFAMILY SSF53335 193 361 2.2E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS24850 8304039def5bda7f854b12bb2e925142 1117 SUPERFAMILY SSF53335 762 877 2.2E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS24850 8304039def5bda7f854b12bb2e925142 1117 SUPERFAMILY SSF53335 529 557 2.2E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS24850 8304039def5bda7f854b12bb2e925142 1117 SUPERFAMILY SSF53335 595 655 2.2E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS24850 8304039def5bda7f854b12bb2e925142 1117 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 767 773 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS24850 8304039def5bda7f854b12bb2e925142 1117 Gene3D G3DSA:3.40.50.150 340 999 1.5E-31 T 29-03-2018 THSYN_RS25910 8142d8e4f7c783f2458a360c2134fc32 575 SUPERFAMILY SSF52467 188 360 3.45E-65 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS25910 8142d8e4f7c783f2458a360c2134fc32 575 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 542 6.3E-50 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THSYN_RS25910 8142d8e4f7c783f2458a360c2134fc32 575 SUPERFAMILY SSF52518 370 566 2.21E-69 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS25910 8142d8e4f7c783f2458a360c2134fc32 575 Gene3D G3DSA:3.40.50.1220 199 353 1.4E-51 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS25910 8142d8e4f7c783f2458a360c2134fc32 575 Gene3D G3DSA:3.40.50.970 354 559 1.5E-47 T 29-03-2018 THSYN_RS25910 8142d8e4f7c783f2458a360c2134fc32 575 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 330 2.1E-43 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 THSYN_RS25910 8142d8e4f7c783f2458a360c2134fc32 575 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 170 2.3E-58 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THSYN_RS25910 8142d8e4f7c783f2458a360c2134fc32 575 Gene3D G3DSA:3.40.50.970 1 198 3.2E-65 T 29-03-2018 THSYN_RS25910 8142d8e4f7c783f2458a360c2134fc32 575 SUPERFAMILY SSF52518 3 181 1.36E-65 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold THSYN_RS25910 8142d8e4f7c783f2458a360c2134fc32 575 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 564 7.3E-257 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 THSYN_RS12495 96b72c7a5a0152e62ae2d87aa59d1710 271 Pfam PF03781 Sulfatase-modifying factor enzyme 1 34 263 1.5E-51 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS12495 96b72c7a5a0152e62ae2d87aa59d1710 271 SUPERFAMILY SSF56436 34 265 5.65E-65 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS12495 96b72c7a5a0152e62ae2d87aa59d1710 271 Gene3D G3DSA:3.90.1580.10 25 269 2.7E-66 T 29-03-2018 THSYN_RS02020 c6d7c76723d1f3266b6b65fccb523661 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.7E-15 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS02020 c6d7c76723d1f3266b6b65fccb523661 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.7E-15 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS02020 c6d7c76723d1f3266b6b65fccb523661 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.7E-15 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS02020 c6d7c76723d1f3266b6b65fccb523661 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site THSYN_RS02020 c6d7c76723d1f3266b6b65fccb523661 89 Pfam PF00381 PTS HPr component phosphorylation site 4 81 4.1E-26 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS02020 c6d7c76723d1f3266b6b65fccb523661 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 1.8E-29 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS02020 c6d7c76723d1f3266b6b65fccb523661 89 SUPERFAMILY SSF55594 1 88 3.93E-27 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS02020 c6d7c76723d1f3266b6b65fccb523661 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site THSYN_RS02020 c6d7c76723d1f3266b6b65fccb523661 89 Gene3D G3DSA:3.30.1340.10 1 87 4.0E-28 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like THSYN_RS11340 a2151d979614cbf54feb7f466730e791 396 SUPERFAMILY SSF53187 4 180 5.71E-53 T 29-03-2018 THSYN_RS11340 a2151d979614cbf54feb7f466730e791 396 SUPERFAMILY SSF53187 301 382 5.71E-53 T 29-03-2018 THSYN_RS11340 a2151d979614cbf54feb7f466730e791 396 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 12 375 2.5E-116 T 29-03-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 THSYN_RS11340 a2151d979614cbf54feb7f466730e791 396 Gene3D G3DSA:3.30.70.360 184 298 1.9E-25 T 29-03-2018 THSYN_RS11340 a2151d979614cbf54feb7f466730e791 396 SUPERFAMILY SSF55031 181 296 1.94E-22 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain THSYN_RS11340 a2151d979614cbf54feb7f466730e791 396 Pfam PF01546 Peptidase family M20/M25/M40 77 379 1.7E-32 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 THSYN_RS11340 a2151d979614cbf54feb7f466730e791 396 Pfam PF07687 Peptidase dimerisation domain 178 287 2.5E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain THSYN_RS11340 a2151d979614cbf54feb7f466730e791 396 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 110 146 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 THSYN_RS11340 a2151d979614cbf54feb7f466730e791 396 Gene3D G3DSA:3.40.630.10 2 183 8.6E-26 T 29-03-2018 THSYN_RS14815 3819a3a0120a12baa7b3001e667be75d 323 Gene3D G3DSA:3.40.50.1820 1 294 1.0E-8 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS14815 3819a3a0120a12baa7b3001e667be75d 323 PIRSF PIRSF029171 1 274 6.1E-18 T 29-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 THSYN_RS14815 3819a3a0120a12baa7b3001e667be75d 323 SUPERFAMILY SSF53474 1 106 5.98E-7 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS14815 3819a3a0120a12baa7b3001e667be75d 323 SUPERFAMILY SSF53474 167 232 5.98E-7 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS22500 6df17f070f975783cd828fe70e1ffe56 966 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 474 480 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS22500 6df17f070f975783cd828fe70e1ffe56 966 SUPERFAMILY SSF53335 158 318 6.14E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS22500 6df17f070f975783cd828fe70e1ffe56 966 SUPERFAMILY SSF53335 356 586 6.14E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS22500 6df17f070f975783cd828fe70e1ffe56 966 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 471 483 8.2E-6 T 29-03-2018 THSYN_RS22500 6df17f070f975783cd828fe70e1ffe56 966 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 360 374 8.2E-6 T 29-03-2018 THSYN_RS22500 6df17f070f975783cd828fe70e1ffe56 966 Pfam PF02384 N-6 DNA Methylase 359 482 3.8E-5 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS22500 6df17f070f975783cd828fe70e1ffe56 966 Gene3D G3DSA:3.40.50.150 298 685 4.8E-21 T 29-03-2018 THSYN_RS05880 14062caa923d674a49f8ec05d49db9db 143 Pfam PF15970 HicB_like antitoxin of bacterial toxin-antitoxin system 5 83 1.5E-7 T 29-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system THSYN_RS05880 14062caa923d674a49f8ec05d49db9db 143 SUPERFAMILY SSF143100 1 65 2.75E-14 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS05880 14062caa923d674a49f8ec05d49db9db 143 Gene3D G3DSA:3.30.2390.10 4 74 2.0E-14 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS14740 134d5f0a20206010b8f29c9726e415ed 355 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 70 283 4.2E-16 T 29-03-2018 IPR000477 Reverse transcriptase domain THSYN_RS14740 134d5f0a20206010b8f29c9726e415ed 355 Gene3D G3DSA:3.30.70.270 100 284 3.6E-19 T 29-03-2018 THSYN_RS14740 134d5f0a20206010b8f29c9726e415ed 355 SUPERFAMILY SSF56672 40 287 6.99E-28 T 29-03-2018 THSYN_RS03820 87343bf1524887281bc6b943a611331c 65 Pfam PF11127 Protein of unknown function (DUF2892) 1 60 1.1E-18 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 THSYN_RS11735 463955a766bf8517c0e55b45bc62a3d8 226 Gene3D G3DSA:3.40.50.10140 5 138 4.3E-7 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS11735 463955a766bf8517c0e55b45bc62a3d8 226 Pfam PF13676 TIR domain 10 131 1.4E-6 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS24205 bd2a18a2114bea328f47a93265d2e695 133 Gene3D G3DSA:1.10.860.10 6 106 6.7E-4 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal THSYN_RS15910 9fdfb4685254101deddcc11c481920da 273 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 138 150 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 THSYN_RS15910 9fdfb4685254101deddcc11c481920da 273 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 272 1.6E-78 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 THSYN_RS15910 9fdfb4685254101deddcc11c481920da 273 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 273 19.627 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 THSYN_RS15910 9fdfb4685254101deddcc11c481920da 273 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 267 1.2E-80 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 THSYN_RS20070 7b60bd1c118dc1db2dc17d928dd60b53 130 SUPERFAMILY SSF55174 8 103 5.63E-25 T 29-03-2018 THSYN_RS20070 7b60bd1c118dc1db2dc17d928dd60b53 130 PIRSF PIRSF016821 7 130 8.7E-41 T 29-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 THSYN_RS20070 7b60bd1c118dc1db2dc17d928dd60b53 130 SMART SM00363 10 71 2.6E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS20070 7b60bd1c118dc1db2dc17d928dd60b53 130 Pfam PF01479 S4 domain 10 56 6.8E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS20070 7b60bd1c118dc1db2dc17d928dd60b53 130 Gene3D G3DSA:3.10.290.10 5 106 7.0E-23 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 THSYN_RS14305 5be076448f8a8fb86fe6b1ff3604655f 114 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 23 108 1.5E-22 T 29-03-2018 IPR009241 Toxin HigB-like THSYN_RS19405 43b6455d697bf6269bab4120c569a536 319 Pfam PF09709 CRISPR-associated protein (Cas_Csd1) 7 295 7.1E-61 T 29-03-2018 IPR010144 CRISPR-associated protein, Csd1-type THSYN_RS31235 32034813451138bc03612ab2f0cb3e2c 478 Gene3D G3DSA:3.40.50.300 3 225 6.4E-20 T 29-03-2018 THSYN_RS31235 32034813451138bc03612ab2f0cb3e2c 478 Pfam PF01926 50S ribosome-binding GTPase 8 134 8.2E-13 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 THSYN_RS31235 32034813451138bc03612ab2f0cb3e2c 478 Pfam PF11981 Domain of unknown function (DUF3482) 160 448 1.5E-59 T 29-03-2018 IPR021871 Protein of unknown function DUF3482 THSYN_RS31235 32034813451138bc03612ab2f0cb3e2c 478 SUPERFAMILY SSF52540 5 66 9.81E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31235 32034813451138bc03612ab2f0cb3e2c 478 SUPERFAMILY SSF52540 108 165 9.81E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05825 d43173c37489f2d645f16b2b0dd6fe2d 268 SUPERFAMILY SSF56300 1 200 1.3E-36 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS05825 d43173c37489f2d645f16b2b0dd6fe2d 268 ProSitePatterns PS00125 Serine/threonine specific protein phosphatases signature. 56 61 - T 29-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THSYN_RS05825 d43173c37489f2d645f16b2b0dd6fe2d 268 Gene3D G3DSA:3.60.21.10 1 211 5.1E-32 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS05825 d43173c37489f2d645f16b2b0dd6fe2d 268 Pfam PF00149 Calcineurin-like phosphoesterase 1 176 1.2E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS06050 cc7f6706935e3c044a69e58cbf5588e4 67 Pfam PF10047 Protein of unknown function (DUF2281) 9 61 2.3E-6 T 29-03-2018 IPR018739 Domain of unknown function DUF2281 THSYN_RS32770 72cb0ca3f83147066166dffa4b554d1a 192 Pfam PF10816 Domain of unknown function (DUF2760) 69 191 4.0E-50 T 29-03-2018 IPR021212 Domain of unknown function DUF2760 THSYN_RS22100 a672f939ea839f6e03eb7d765dbf5b25 185 Pfam PF13424 Tetratricopeptide repeat 97 168 3.8E-12 T 29-03-2018 THSYN_RS22100 a672f939ea839f6e03eb7d765dbf5b25 185 SUPERFAMILY SSF48452 59 174 4.51E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22100 a672f939ea839f6e03eb7d765dbf5b25 185 SMART SM00028 96 129 0.03 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22100 a672f939ea839f6e03eb7d765dbf5b25 185 SMART SM00028 136 169 0.069 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22100 a672f939ea839f6e03eb7d765dbf5b25 185 SMART SM00028 56 89 0.19 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22100 a672f939ea839f6e03eb7d765dbf5b25 185 Pfam PF13176 Tetratricopeptide repeat 59 92 6.6E-6 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS22100 a672f939ea839f6e03eb7d765dbf5b25 185 Gene3D G3DSA:3.30.70.100 32 98 5.9E-15 T 29-03-2018 THSYN_RS22100 a672f939ea839f6e03eb7d765dbf5b25 185 Gene3D G3DSA:3.30.70.100 99 137 1.6E-14 T 29-03-2018 THSYN_RS22100 a672f939ea839f6e03eb7d765dbf5b25 185 Gene3D G3DSA:3.30.70.100 138 180 1.5E-7 T 29-03-2018 THSYN_RS06300 561258355e82ba173f35054820b67ba7 309 SMART SM00893 3 182 6.3E-48 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 THSYN_RS06300 561258355e82ba173f35054820b67ba7 309 SUPERFAMILY SSF52467 187 308 2.86E-48 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS06300 561258355e82ba173f35054820b67ba7 309 PIRSF PIRSF000089 1 309 1.5E-106 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 THSYN_RS06300 561258355e82ba173f35054820b67ba7 309 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 253 279 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 THSYN_RS06300 561258355e82ba173f35054820b67ba7 309 Gene3D G3DSA:3.40.50.1220 185 309 2.6E-58 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS06300 561258355e82ba173f35054820b67ba7 309 Pfam PF01012 Electron transfer flavoprotein domain 4 167 4.9E-36 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 THSYN_RS06300 561258355e82ba173f35054820b67ba7 309 SUPERFAMILY SSF52402 2 185 1.19E-53 T 29-03-2018 THSYN_RS06300 561258355e82ba173f35054820b67ba7 309 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 272 1.7E-37 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 THSYN_RS06300 561258355e82ba173f35054820b67ba7 309 Gene3D G3DSA:3.40.50.620 1 180 1.2E-38 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS17750 99590dbed56ba22e7eabae8907fc9e4e 578 SUPERFAMILY SSF56300 155 351 2.85E-22 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS17750 99590dbed56ba22e7eabae8907fc9e4e 578 SUPERFAMILY SSF56300 28 127 2.85E-22 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS17750 99590dbed56ba22e7eabae8907fc9e4e 578 Gene3D G3DSA:3.60.21.10 24 376 3.6E-23 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS17750 99590dbed56ba22e7eabae8907fc9e4e 578 Pfam PF00149 Calcineurin-like phosphoesterase 32 278 2.5E-8 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS13115 5b725b80b1c00a97e097b1d7000c094c 173 Pfam PF03473 MOSC domain 57 155 5.0E-9 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 THSYN_RS13115 5b725b80b1c00a97e097b1d7000c094c 173 Gene3D G3DSA:2.40.33.20 8 170 2.1E-27 T 29-03-2018 THSYN_RS13115 5b725b80b1c00a97e097b1d7000c094c 173 SUPERFAMILY SSF50800 13 157 1.31E-34 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain THSYN_RS05190 ec332f070151ddda9afb529ca507582a 186 Pfam PF02342 TerD domain 3 181 2.5E-57 T 29-03-2018 IPR003325 TerD domain GO:0006950 THSYN_RS05190 ec332f070151ddda9afb529ca507582a 186 Gene3D G3DSA:2.60.60.30 18 180 7.5E-47 T 29-03-2018 THSYN_RS07650 0926ff48e235a0d9cf5d1773fe380c6c 317 SUPERFAMILY SSF64182 5 315 1.33E-42 T 29-03-2018 THSYN_RS33040 8e980b8f11eb4582a00806e63c187357 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 232 9.3E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS33040 8e980b8f11eb4582a00806e63c187357 249 Gene3D G3DSA:1.10.3720.10 48 245 3.0E-26 T 29-03-2018 THSYN_RS33040 8e980b8f11eb4582a00806e63c187357 249 SUPERFAMILY SSF161098 51 233 6.02E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS20260 7677b8a18936f3c82765e38c0650ee09 122 Gene3D G3DSA:1.10.10.10 3 119 1.4E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS20260 7677b8a18936f3c82765e38c0650ee09 122 SUPERFAMILY SSF46785 51 107 1.69E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS31130 8d1f83de4dc23d43f9b3794670f9593f 509 SUPERFAMILY SSF53850 145 462 1.99E-6 T 29-03-2018 THSYN_RS31130 8d1f83de4dc23d43f9b3794670f9593f 509 Gene3D G3DSA:3.40.190.10 27 461 2.0E-5 T 29-03-2018 THSYN_RS31130 8d1f83de4dc23d43f9b3794670f9593f 509 Pfam PF13531 Bacterial extracellular solute-binding protein 147 447 3.5E-16 T 29-03-2018 THSYN_RS01140 ba70a50c00ee224d781105dd6b5792e6 1076 Gene3D G3DSA:1.25.40.10 255 674 0.019 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01140 ba70a50c00ee224d781105dd6b5792e6 1076 Gene3D G3DSA:1.25.40.10 51 246 0.0059 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS01140 ba70a50c00ee224d781105dd6b5792e6 1076 Gene3D G3DSA:3.40.50.1460 866 1050 2.5E-12 T 29-03-2018 THSYN_RS01140 ba70a50c00ee224d781105dd6b5792e6 1076 Pfam PF12770 CHAT domain 765 1048 7.6E-34 T 29-03-2018 IPR024983 CHAT domain THSYN_RS16950 f6c5d8815137c776a76495e9ffaf5efb 63 SUPERFAMILY SSF143100 4 44 8.11E-10 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS16950 f6c5d8815137c776a76495e9ffaf5efb 63 Gene3D G3DSA:3.30.2390.10 3 54 5.0E-9 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS31770 15622129f11a8eb61ce786c1742e78c0 1120 Pfam PF13558 Putative exonuclease SbcCD, C subunit 975 1065 9.3E-23 T 29-03-2018 THSYN_RS31770 15622129f11a8eb61ce786c1742e78c0 1120 SUPERFAMILY SSF52540 21 189 1.83E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31770 15622129f11a8eb61ce786c1742e78c0 1120 SUPERFAMILY SSF52540 988 1075 1.83E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31770 15622129f11a8eb61ce786c1742e78c0 1120 Gene3D G3DSA:3.40.50.300 21 1116 4.6E-19 T 29-03-2018 THSYN_RS31770 15622129f11a8eb61ce786c1742e78c0 1120 Pfam PF13555 P-loop containing region of AAA domain 22 82 1.7E-24 T 29-03-2018 THSYN_RS16525 8cafb6501729bcefc60225a7dae355ef 248 Gene3D G3DSA:1.25.10.10 14 244 4.6E-7 T 29-03-2018 IPR011989 Armadillo-like helical THSYN_RS16525 8cafb6501729bcefc60225a7dae355ef 248 SUPERFAMILY SSF48371 131 154 2.48E-5 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS16525 8cafb6501729bcefc60225a7dae355ef 248 SUPERFAMILY SSF48371 32 83 2.48E-5 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS16525 8cafb6501729bcefc60225a7dae355ef 248 SUPERFAMILY SSF48371 185 243 2.48E-5 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS32765 5be8091979ea4af0ccaf7faf048258a5 615 Gene3D G3DSA:3.30.420.40 226 436 6.0E-15 T 29-03-2018 THSYN_RS32765 5be8091979ea4af0ccaf7faf048258a5 615 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 221 234 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THSYN_RS32765 5be8091979ea4af0ccaf7faf048258a5 615 SUPERFAMILY SSF53067 5 202 2.36E-29 T 29-03-2018 THSYN_RS32765 5be8091979ea4af0ccaf7faf048258a5 615 PRINTS PR00301 70kDa heat shock protein signature 227 237 1.4E-7 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS32765 5be8091979ea4af0ccaf7faf048258a5 615 PRINTS PR00301 70kDa heat shock protein signature 6 19 1.4E-7 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS32765 5be8091979ea4af0ccaf7faf048258a5 615 PRINTS PR00301 70kDa heat shock protein signature 160 180 1.4E-7 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS32765 5be8091979ea4af0ccaf7faf048258a5 615 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 10 17 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THSYN_RS32765 5be8091979ea4af0ccaf7faf048258a5 615 Pfam PF00012 Hsp70 protein 156 300 3.2E-14 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS32765 5be8091979ea4af0ccaf7faf048258a5 615 SUPERFAMILY SSF53067 217 366 4.09E-24 T 29-03-2018 THSYN_RS32765 5be8091979ea4af0ccaf7faf048258a5 615 SUPERFAMILY SSF53067 403 461 4.09E-24 T 29-03-2018 THSYN_RS32765 5be8091979ea4af0ccaf7faf048258a5 615 Gene3D G3DSA:3.30.420.40 4 225 2.7E-33 T 29-03-2018 THSYN_RS18685 01dcfc9bd3b3027528e4e20621ef2af7 78 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 3 46 6.5E-13 T 29-03-2018 IPR022453 Zinc finger, MqsA-type THSYN_RS08340 5ee7dc1c1ebc6269fdc5254a368a8c5d 372 SUPERFAMILY SSF48452 271 358 1.14E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS08340 5ee7dc1c1ebc6269fdc5254a368a8c5d 372 Gene3D G3DSA:1.25.40.10 163 370 5.5E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS20405 36cd98a02fede99c399fb9064f18eefc 203 Gene3D G3DSA:1.10.3540.10 5 196 1.3E-54 T 29-03-2018 THSYN_RS20405 36cd98a02fede99c399fb9064f18eefc 203 Pfam PF08849 Putative inner membrane protein (DUF1819) 6 188 8.0E-44 T 29-03-2018 IPR014948 Protein of unknown function DUF1819, putative inner membrane THSYN_RS28985 12b352eb7486adfac68c1eca8fb18ae7 656 SUPERFAMILY SSF56235 1 228 3.09E-63 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS28985 12b352eb7486adfac68c1eca8fb18ae7 656 Pfam PF00733 Asparagine synthase 252 643 4.1E-111 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THSYN_RS28985 12b352eb7486adfac68c1eca8fb18ae7 656 PIRSF PIRSF001589 1 655 4.2E-158 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS28985 12b352eb7486adfac68c1eca8fb18ae7 656 Pfam PF13537 Glutamine amidotransferase domain 51 170 1.6E-43 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain THSYN_RS28985 12b352eb7486adfac68c1eca8fb18ae7 656 Gene3D G3DSA:3.40.50.620 227 651 3.1E-79 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS28985 12b352eb7486adfac68c1eca8fb18ae7 656 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 579 2.5E-140 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THSYN_RS28985 12b352eb7486adfac68c1eca8fb18ae7 656 SUPERFAMILY SSF52402 499 639 1.95E-92 T 29-03-2018 THSYN_RS28985 12b352eb7486adfac68c1eca8fb18ae7 656 SUPERFAMILY SSF52402 242 392 1.95E-92 T 29-03-2018 THSYN_RS28985 12b352eb7486adfac68c1eca8fb18ae7 656 Gene3D G3DSA:3.60.20.10 1 226 6.8E-54 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS02450 b5589b6ed7abfd38fd2fafe68f2b09a7 301 Pfam PF13489 Methyltransferase domain 93 252 5.3E-19 T 29-03-2018 THSYN_RS02450 b5589b6ed7abfd38fd2fafe68f2b09a7 301 Gene3D G3DSA:3.40.50.150 62 275 3.3E-28 T 29-03-2018 THSYN_RS02450 b5589b6ed7abfd38fd2fafe68f2b09a7 301 SUPERFAMILY SSF53335 89 269 1.67E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS12225 e7ecdfe167f9039c9e37c7a071cc0dbb 127 Pfam PF03683 Uncharacterised protein family (UPF0175) 56 110 1.6E-10 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS02550 03450d33e751b858773bad5af2dccd17 270 Pfam PF03649 Uncharacterised protein family (UPF0014) 9 251 7.7E-86 T 29-03-2018 IPR005226 UPF0014 family THSYN_RS02550 03450d33e751b858773bad5af2dccd17 270 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 9 257 7.1E-56 T 29-03-2018 IPR005226 UPF0014 family THSYN_RS21820 76697d359a304066559346294014b3af 411 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 32 366 2.1E-79 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS21820 76697d359a304066559346294014b3af 411 SUPERFAMILY SSF111369 46 290 7.72E-63 T 29-03-2018 THSYN_RS21820 76697d359a304066559346294014b3af 411 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 53 285 4.7E-12 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS21820 76697d359a304066559346294014b3af 411 Pfam PF00529 HlyD membrane-fusion protein of T1SS 155 352 1.4E-7 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS21820 76697d359a304066559346294014b3af 411 Gene3D G3DSA:1.20.1600.10 48 305 3.1E-23 T 29-03-2018 THSYN_RS28500 1e631a01f114885e1212e7b3542c651c 127 Pfam PF03061 Thioesterase superfamily 44 111 7.7E-14 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 THSYN_RS28500 1e631a01f114885e1212e7b3542c651c 127 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 18 110 7.4E-20 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 THSYN_RS28500 1e631a01f114885e1212e7b3542c651c 127 Gene3D G3DSA:3.10.129.10 7 126 5.5E-26 T 29-03-2018 THSYN_RS28500 1e631a01f114885e1212e7b3542c651c 127 SUPERFAMILY SSF54637 9 125 1.01E-28 T 29-03-2018 IPR029069 HotDog domain THSYN_RS31320 8fefb56b42c069a12003e0f86910e7db 497 Pfam PF01593 Flavin containing amine oxidoreductase 13 491 5.6E-16 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THSYN_RS31320 8fefb56b42c069a12003e0f86910e7db 497 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 6 495 4.8E-80 T 29-03-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 THSYN_RS31320 8fefb56b42c069a12003e0f86910e7db 497 Gene3D G3DSA:3.50.50.60 2 497 5.4E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31320 8fefb56b42c069a12003e0f86910e7db 497 SUPERFAMILY SSF51905 453 495 2.16E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31320 8fefb56b42c069a12003e0f86910e7db 497 SUPERFAMILY SSF51905 1 322 2.16E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS11900 ccbd581d69d731dbf3309d4570246571 254 Gene3D G3DSA:1.10.246.10 151 227 0.0017 T 29-03-2018 THSYN_RS11900 ccbd581d69d731dbf3309d4570246571 254 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 12 248 1.4E-56 T 29-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 THSYN_RS01845 61c927c4111a8b76da73c2412596c582 339 Gene3D G3DSA:3.30.420.10 106 321 1.4E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS05500 ca158995875633a99b1313e73b176d3e 177 Pfam PF11086 Protein of unknown function (DUF2878) 1 154 2.2E-46 T 29-03-2018 IPR021306 Protein of unknown function DUF2878 THSYN_RS30905 43226f7e530ddc4eef412cd4dffbf713 97 Gene3D G3DSA:3.50.50.60 12 93 2.4E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS30905 43226f7e530ddc4eef412cd4dffbf713 97 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 32 85 2.2E-18 T 29-03-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system THSYN_RS16320 153f2d3d4d6714400d99b9da92803d27 60 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 4 59 1.5E-16 T 29-03-2018 IPR019201 Protein of unknown function DUF2065 THSYN_RS02240 4a975792e1b65c61e45efb1097d17381 887 SUPERFAMILY SSF52540 754 831 4.59E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02240 4a975792e1b65c61e45efb1097d17381 887 SUPERFAMILY SSF52540 590 677 4.59E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02240 4a975792e1b65c61e45efb1097d17381 887 SUPERFAMILY SSF52540 274 459 4.59E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02240 4a975792e1b65c61e45efb1097d17381 887 Gene3D G3DSA:3.40.50.300 264 839 1.5E-24 T 29-03-2018 THSYN_RS02240 4a975792e1b65c61e45efb1097d17381 887 Gene3D G3DSA:3.20.20.140 37 231 0.0015 T 29-03-2018 THSYN_RS02240 4a975792e1b65c61e45efb1097d17381 887 SUPERFAMILY SSF89550 46 160 1.39E-9 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 THSYN_RS02240 4a975792e1b65c61e45efb1097d17381 887 Pfam PF13476 AAA domain 276 331 9.6E-7 T 29-03-2018 THSYN_RS01750 0746d539ec59f3c4d6e1014b38b91469 189 Gene3D G3DSA:3.90.1570.10 5 189 3.6E-33 T 29-03-2018 THSYN_RS01750 0746d539ec59f3c4d6e1014b38b91469 189 Pfam PF05685 Putative restriction endonuclease 17 183 1.6E-28 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS01750 0746d539ec59f3c4d6e1014b38b91469 189 SUPERFAMILY SSF52980 10 189 1.88E-20 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS10860 398a723a48591dd55c286d1e72107f65 310 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 45 59 1.2E-10 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS10860 398a723a48591dd55c286d1e72107f65 310 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 237 254 1.2E-10 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS10860 398a723a48591dd55c286d1e72107f65 310 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 257 275 1.2E-10 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS10860 398a723a48591dd55c286d1e72107f65 310 Pfam PF01555 DNA methylase 47 295 1.1E-12 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THSYN_RS10860 398a723a48591dd55c286d1e72107f65 310 SUPERFAMILY SSF53335 99 299 6.94E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS10860 398a723a48591dd55c286d1e72107f65 310 SUPERFAMILY SSF53335 27 67 6.94E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS10860 398a723a48591dd55c286d1e72107f65 310 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 49 55 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS10860 398a723a48591dd55c286d1e72107f65 310 Gene3D G3DSA:3.40.50.150 22 300 1.1E-26 T 29-03-2018 THSYN_RS12910 f958baf3be6744486950ad182a232386 360 SUPERFAMILY SSF52317 20 273 3.57E-68 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS12910 f958baf3be6744486950ad182a232386 360 SUPERFAMILY SSF52317 302 333 3.57E-68 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS12910 f958baf3be6744486950ad182a232386 360 Gene3D G3DSA:3.40.50.880 34 338 3.1E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS12910 f958baf3be6744486950ad182a232386 360 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 35 255 7.0E-94 T 29-03-2018 THSYN_RS12910 f958baf3be6744486950ad182a232386 360 Pfam PF04204 Homoserine O-succinyltransferase 2 335 1.0E-87 T 29-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 THSYN_RS27765 af700c8f8b35c48a33b065988c08eed8 316 Pfam PF04754 Putative transposase, YhgA-like 10 204 6.4E-42 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS24935 554d7d5af41092f8c9847cf70065ae68 311 Pfam PF01515 Phosphate acetyl/butaryl transferase 16 80 2.9E-5 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS24935 554d7d5af41092f8c9847cf70065ae68 311 Pfam PF01515 Phosphate acetyl/butaryl transferase 85 302 8.4E-36 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS24935 554d7d5af41092f8c9847cf70065ae68 311 SUPERFAMILY SSF53659 19 305 2.38E-51 T 29-03-2018 THSYN_RS24935 554d7d5af41092f8c9847cf70065ae68 311 PIRSF PIRSF000428 1 309 1.2E-73 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THSYN_RS24935 554d7d5af41092f8c9847cf70065ae68 311 Gene3D G3DSA:3.40.50.10750 118 277 1.1E-34 T 29-03-2018 THSYN_RS09120 ae1b1b84ea87403d990b3ed7eaff2f8e 71 Pfam PF09720 Putative addiction module component 9 61 7.3E-17 T 29-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THSYN_RS32280 2e8b00d9eed110f621709ac215799ca5 312 Gene3D G3DSA:2.130.10.150 23 172 7.9E-11 T 29-03-2018 THSYN_RS32280 2e8b00d9eed110f621709ac215799ca5 312 Gene3D G3DSA:2.130.10.150 173 311 1.5E-23 T 29-03-2018 THSYN_RS32280 2e8b00d9eed110f621709ac215799ca5 312 SUPERFAMILY SSF82171 23 294 6.67E-30 T 29-03-2018 THSYN_RS32280 2e8b00d9eed110f621709ac215799ca5 312 Pfam PF07676 WD40-like Beta Propeller Repeat 243 275 3.0E-9 T 29-03-2018 IPR011659 WD40-like Beta Propeller THSYN_RS32280 2e8b00d9eed110f621709ac215799ca5 312 Pfam PF07676 WD40-like Beta Propeller Repeat 54 86 0.0012 T 29-03-2018 IPR011659 WD40-like Beta Propeller THSYN_RS32280 2e8b00d9eed110f621709ac215799ca5 312 Pfam PF07676 WD40-like Beta Propeller Repeat 147 172 0.0044 T 29-03-2018 IPR011659 WD40-like Beta Propeller THSYN_RS32280 2e8b00d9eed110f621709ac215799ca5 312 Pfam PF07676 WD40-like Beta Propeller Repeat 200 235 6.3E-10 T 29-03-2018 IPR011659 WD40-like Beta Propeller THSYN_RS31285 ebe03e660eaa98de490c9d86d1fa534c 83 Gene3D G3DSA:4.10.220.20 21 64 2.7E-15 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31285 ebe03e660eaa98de490c9d86d1fa534c 83 SUPERFAMILY SSF56918 17 68 2.25E-8 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS32090 b8e7aa930e4c3b1dfe7410c03a0f7383 272 SUPERFAMILY SSF89392 39 244 7.46E-10 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX THSYN_RS32090 b8e7aa930e4c3b1dfe7410c03a0f7383 272 Gene3D G3DSA:2.50.20.10 34 245 2.1E-18 T 29-03-2018 THSYN_RS32090 b8e7aa930e4c3b1dfe7410c03a0f7383 272 Pfam PF09865 Predicted periplasmic protein (DUF2092) 37 245 7.8E-63 T 29-03-2018 IPR019207 Protein of unknown function DUF2092, periplasmic THSYN_RS29670 86d2dc0672499035920d47a83743fced 100 Gene3D G3DSA:3.40.50.620 3 100 9.2E-15 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS29670 86d2dc0672499035920d47a83743fced 100 SUPERFAMILY SSF52402 51 99 1.05E-14 T 29-03-2018 THSYN_RS29670 86d2dc0672499035920d47a83743fced 100 PRINTS PR01438 Universal stress protein signature 75 97 8.5E-8 T 29-03-2018 IPR006015 Universal stress protein A THSYN_RS29670 86d2dc0672499035920d47a83743fced 100 PRINTS PR01438 Universal stress protein signature 57 69 8.5E-8 T 29-03-2018 IPR006015 Universal stress protein A THSYN_RS29670 86d2dc0672499035920d47a83743fced 100 Pfam PF00582 Universal stress protein family 51 97 1.0E-12 T 29-03-2018 IPR006016 UspA GO:0006950 THSYN_RS24725 3a0849175f43e703eaf32441f9d2687e 96 Pfam PF08681 Protein of unknown function (DUF1778) 14 89 9.8E-26 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 THSYN_RS24725 3a0849175f43e703eaf32441f9d2687e 96 SUPERFAMILY SSF47598 10 87 1.28E-21 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS24725 3a0849175f43e703eaf32441f9d2687e 96 Gene3D G3DSA:1.20.5.780 10 89 2.3E-27 T 29-03-2018 THSYN_RS12975 bdce58e3085cc2a656736813f7b37f8c 115 Gene3D G3DSA:2.30.30.110 3 115 1.6E-16 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS12975 bdce58e3085cc2a656736813f7b37f8c 115 SUPERFAMILY SSF50118 6 115 1.9E-16 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS12975 bdce58e3085cc2a656736813f7b37f8c 115 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 6 111 4.8E-14 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS10755 0c9ca2e7c7e6c4b245d736eadb1206e3 585 Gene3D G3DSA:3.30.420.10 194 350 0.0017 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS06490 7e996b67f69fc6c7420fdd4f6e7626c3 109 Pfam PF13676 TIR domain 10 108 2.2E-23 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS06490 7e996b67f69fc6c7420fdd4f6e7626c3 109 Gene3D G3DSA:3.40.50.10140 9 107 1.9E-15 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS06490 7e996b67f69fc6c7420fdd4f6e7626c3 109 SUPERFAMILY SSF52200 8 106 1.96E-17 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS18150 3a5d2ed2183d65fb278210d2f752bec1 552 Gene3D G3DSA:3.40.720.10 25 262 1.5E-46 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS18150 3a5d2ed2183d65fb278210d2f752bec1 552 Gene3D G3DSA:3.40.720.10 263 390 1.7E-21 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS18150 3a5d2ed2183d65fb278210d2f752bec1 552 Pfam PF00884 Sulfatase 28 363 3.3E-56 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THSYN_RS18150 3a5d2ed2183d65fb278210d2f752bec1 552 ProSitePatterns PS00149 Sulfatases signature 2. 124 134 - T 29-03-2018 IPR024607 Sulfatase, conserved site THSYN_RS18150 3a5d2ed2183d65fb278210d2f752bec1 552 Gene3D G3DSA:3.30.1120.10 392 480 0.0028 T 29-03-2018 THSYN_RS18150 3a5d2ed2183d65fb278210d2f752bec1 552 SUPERFAMILY SSF53649 24 469 3.66E-89 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS08685 1816cc50454e3a921147c6356b738850 101 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 20 92 1.3E-31 T 29-03-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 THSYN_RS15185 baa84a81b4b752615774c430533c7e24 195 SUPERFAMILY SSF52980 15 194 1.29E-20 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS15185 baa84a81b4b752615774c430533c7e24 195 Gene3D G3DSA:3.90.1570.10 10 195 2.0E-33 T 29-03-2018 THSYN_RS15185 baa84a81b4b752615774c430533c7e24 195 Pfam PF05685 Putative restriction endonuclease 23 190 4.3E-31 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS09055 a194cd1fa7be1bf757600ddac55330f3 338 Gene3D G3DSA:3.40.718.10 1 330 9.8E-114 T 29-03-2018 THSYN_RS09055 a194cd1fa7be1bf757600ddac55330f3 338 SUPERFAMILY SSF53659 3 329 1.25E-92 T 29-03-2018 THSYN_RS09055 a194cd1fa7be1bf757600ddac55330f3 338 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 6 326 2.3E-95 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 THSYN_RS09055 a194cd1fa7be1bf757600ddac55330f3 338 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 34 322 2.0E-91 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 THSYN_RS09055 a194cd1fa7be1bf757600ddac55330f3 338 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 2 327 31.487 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 THSYN_RS20110 967bdc41d8323f68f956129ced763af7 315 Pfam PF01148 Cytidylyltransferase family 48 313 3.2E-64 T 29-03-2018 THSYN_RS32745 b24d2aa8ed7a65d8d87a86b82fb02e3e 267 SUPERFAMILY SSF49879 162 259 4.78E-22 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 THSYN_RS32745 b24d2aa8ed7a65d8d87a86b82fb02e3e 267 Gene3D G3DSA:2.60.200.20 151 266 5.1E-20 T 29-03-2018 THSYN_RS32745 b24d2aa8ed7a65d8d87a86b82fb02e3e 267 SUPERFAMILY SSF52200 3 114 2.22E-21 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS32745 b24d2aa8ed7a65d8d87a86b82fb02e3e 267 SMART SM00240 182 236 3.6E-12 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THSYN_RS32745 b24d2aa8ed7a65d8d87a86b82fb02e3e 267 Pfam PF13676 TIR domain 4 111 7.5E-18 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS32745 b24d2aa8ed7a65d8d87a86b82fb02e3e 267 Pfam PF00498 FHA domain 184 251 6.3E-15 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THSYN_RS32745 b24d2aa8ed7a65d8d87a86b82fb02e3e 267 Gene3D G3DSA:3.40.50.10140 1 122 6.6E-22 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS02115 9d80ee482b7566e26a0fd11d1452d11b 205 PIRSF PIRSF004649 1 205 4.8E-57 T 29-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC THSYN_RS02115 9d80ee482b7566e26a0fd11d1452d11b 205 Pfam PF05494 MlaC protein 35 196 1.3E-55 T 29-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC THSYN_RS02115 9d80ee482b7566e26a0fd11d1452d11b 205 Gene3D G3DSA:1.10.10.640 164 205 4.3E-5 T 29-03-2018 THSYN_RS02115 9d80ee482b7566e26a0fd11d1452d11b 205 Gene3D G3DSA:3.10.450.50 75 163 1.7E-26 T 29-03-2018 THSYN_RS02115 9d80ee482b7566e26a0fd11d1452d11b 205 Gene3D G3DSA:3.10.450.50 28 74 0.05 T 29-03-2018 THSYN_RS08650 5a9410ff1a8b9f4b4d82e52a3ae4e7e2 189 Pfam PF04011 LemA family 7 181 6.2E-55 T 29-03-2018 IPR007156 LemA THSYN_RS08650 5a9410ff1a8b9f4b4d82e52a3ae4e7e2 189 SUPERFAMILY SSF140478 26 175 1.7E-43 T 29-03-2018 IPR023353 LemA-like domain THSYN_RS08650 5a9410ff1a8b9f4b4d82e52a3ae4e7e2 189 Gene3D G3DSA:1.20.1440.20 14 186 5.2E-46 T 29-03-2018 THSYN_RS07105 6ba2386908e4f8af8ff7709d57c4a82d 496 Pfam PF04293 SpoVR like protein 11 443 1.0E-169 T 29-03-2018 IPR007390 Sporulation stage V, protein R THSYN_RS07850 917dbc7957f835ea8476659b56b7a8ca 70 Gene3D G3DSA:1.10.10.10 9 69 1.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS07850 917dbc7957f835ea8476659b56b7a8ca 70 Pfam PF04255 Protein of unknown function (DUF433) 10 64 3.4E-21 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS07850 917dbc7957f835ea8476659b56b7a8ca 70 SUPERFAMILY SSF46689 6 68 8.6E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS04850 aea3b8dfd5db3b09e7b59c1f69e7ccb9 285 SUPERFAMILY SSF51730 3 283 8.63E-96 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like THSYN_RS04850 aea3b8dfd5db3b09e7b59c1f69e7ccb9 285 Pfam PF02219 Methylenetetrahydrofolate reductase 4 278 2.4E-81 T 29-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 THSYN_RS04850 aea3b8dfd5db3b09e7b59c1f69e7ccb9 285 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 11 281 3.4E-96 T 29-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 THSYN_RS04850 aea3b8dfd5db3b09e7b59c1f69e7ccb9 285 Gene3D G3DSA:3.20.20.220 1 285 6.6E-98 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like THSYN_RS08050 54393d99e4ee60766f2207c0bf0aa6a2 115 Pfam PF11006 Protein of unknown function (DUF2845) 25 110 1.1E-13 T 29-03-2018 IPR021268 Protein of unknown function DUF2845 THSYN_RS19675 00b633612229a737298db0c58f507692 173 Pfam PF12019 Type II transport protein GspH 43 161 1.0E-13 T 29-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THSYN_RS19675 00b633612229a737298db0c58f507692 173 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 7.3E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS19675 00b633612229a737298db0c58f507692 173 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 5.7E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS19675 00b633612229a737298db0c58f507692 173 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS19675 00b633612229a737298db0c58f507692 173 Gene3D G3DSA:3.30.700.10 8 170 2.2E-15 T 29-03-2018 THSYN_RS19675 00b633612229a737298db0c58f507692 173 SUPERFAMILY SSF54523 8 148 4.47E-16 T 29-03-2018 THSYN_RS11655 4495d1ca377619965e55ae244ff39cd3 118 Pfam PF05168 HEPN domain 10 109 3.6E-19 T 29-03-2018 IPR007842 HEPN domain THSYN_RS11655 4495d1ca377619965e55ae244ff39cd3 118 SUPERFAMILY SSF81593 10 110 2.63E-27 T 29-03-2018 THSYN_RS11655 4495d1ca377619965e55ae244ff39cd3 118 SMART SM00748 10 104 3.3E-5 T 29-03-2018 IPR007842 HEPN domain THSYN_RS11655 4495d1ca377619965e55ae244ff39cd3 118 Gene3D G3DSA:1.20.120.330 7 113 2.0E-14 T 29-03-2018 THSYN_RS18310 2ff7d4cedd4c928a2f275c6127fafc46 283 Pfam PF00069 Protein kinase domain 58 214 7.4E-9 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS18310 2ff7d4cedd4c928a2f275c6127fafc46 283 Gene3D G3DSA:1.10.510.10 71 271 1.2E-17 T 29-03-2018 THSYN_RS18310 2ff7d4cedd4c928a2f275c6127fafc46 283 SUPERFAMILY SSF56112 54 220 1.26E-19 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS24950 b277fd1fb94b8d7a74759c029b6c0b71 82 SUPERFAMILY SSF89447 1 59 7.32E-12 T 29-03-2018 THSYN_RS24950 b277fd1fb94b8d7a74759c029b6c0b71 82 Gene3D G3DSA:2.10.260.10 1 82 2.0E-12 T 29-03-2018 THSYN_RS24090 cd11388ece823ef4b16abbe773322072 511 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 67 452 3.2E-95 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 THSYN_RS24090 cd11388ece823ef4b16abbe773322072 511 Gene3D G3DSA:3.60.110.10 215 476 3.1E-38 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THSYN_RS24090 cd11388ece823ef4b16abbe773322072 511 SUPERFAMILY SSF56317 222 485 4.84E-43 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THSYN_RS24090 cd11388ece823ef4b16abbe773322072 511 Pfam PF00795 Carbon-nitrogen hydrolase 230 475 1.5E-34 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THSYN_RS24090 cd11388ece823ef4b16abbe773322072 511 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 14 490 22.915 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 THSYN_RS18525 9b105607a0bc2b3af8a4cda8599e28ef 141 Pfam PF10097 Predicted membrane protein (DUF2335) 42 91 6.5E-14 T 29-03-2018 IPR019284 Xylella phage Xfas53, Orf42 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 Gene3D G3DSA:1.10.10.10 190 257 1.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 Gene3D G3DSA:1.10.10.10 150 189 1.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 SUPERFAMILY SSF48452 3 144 3.98E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 Gene3D G3DSA:1.20.58.280 132 149 4.0E-4 T 29-03-2018 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 SUPERFAMILY SSF48452 122 236 3.25E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 Pfam PF13424 Tetratricopeptide repeat 122 197 1.2E-18 T 29-03-2018 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 Pfam PF13424 Tetratricopeptide repeat 43 111 5.5E-12 T 29-03-2018 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 SMART SM00028 165 198 2.9 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 SMART SM00028 81 114 13.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 SMART SM00028 123 156 11.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 SMART SM00028 207 240 240.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 SMART SM00028 39 72 160.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 Pfam PF13374 Tetratricopeptide repeat 3 33 0.0011 T 29-03-2018 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 Gene3D G3DSA:1.20.1250.10 2 64 6.7E-5 T 29-03-2018 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 Gene3D G3DSA:1.20.5.1140 65 82 6.8E-6 T 29-03-2018 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 Gene3D G3DSA:1.25.40.10 258 307 0.14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS26645 2062b05d63969289b3a5a546c294e5c6 315 Gene3D G3DSA:1.10.150.200 83 131 2.2E-12 T 29-03-2018 THSYN_RS18985 1eb53189c95e6bc445de0c83aa7bc4b2 337 Gene3D G3DSA:3.30.70.20 23 50 0.018 T 29-03-2018 THSYN_RS18985 1eb53189c95e6bc445de0c83aa7bc4b2 337 Gene3D G3DSA:3.30.70.20 130 172 3.8E-18 T 29-03-2018 THSYN_RS18985 1eb53189c95e6bc445de0c83aa7bc4b2 337 Gene3D G3DSA:3.30.70.20 173 264 6.9E-14 T 29-03-2018 THSYN_RS18985 1eb53189c95e6bc445de0c83aa7bc4b2 337 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 28 4.0E-4 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THSYN_RS18985 1eb53189c95e6bc445de0c83aa7bc4b2 337 Gene3D G3DSA:3.30.70.20 51 129 6.7E-17 T 29-03-2018 THSYN_RS18985 1eb53189c95e6bc445de0c83aa7bc4b2 337 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 148 159 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS18985 1eb53189c95e6bc445de0c83aa7bc4b2 337 SUPERFAMILY SSF54862 38 316 2.41E-64 T 29-03-2018 THSYN_RS18985 1eb53189c95e6bc445de0c83aa7bc4b2 337 Pfam PF13247 4Fe-4S dicluster domain 109 204 2.9E-22 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS05305 a0067d32c408260041f62ea81ac336b7 93 Pfam PF13020 Domain of unknown function (DUF3883) 10 58 9.7E-7 T 29-03-2018 IPR024975 Domain of unknown function DUF3883 THSYN_RS08400 2e72c0c7b8944e1917e6b2fbac1de949 255 Gene3D G3DSA:2.60.40.680 28 210 2.3E-10 T 29-03-2018 THSYN_RS08400 2e72c0c7b8944e1917e6b2fbac1de949 255 Pfam PF07589 PEP-CTERM motif 225 251 9.0E-5 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS08400 2e72c0c7b8944e1917e6b2fbac1de949 255 SUPERFAMILY SSF49384 43 101 1.64E-5 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 THSYN_RS06315 625ebf8e46d4ae74b1f2b44365d65fd1 70 Gene3D G3DSA:1.10.10.10 1 68 1.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS06315 625ebf8e46d4ae74b1f2b44365d65fd1 70 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 59 1.7E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS06315 625ebf8e46d4ae74b1f2b44365d65fd1 70 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.5E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS06315 625ebf8e46d4ae74b1f2b44365d65fd1 70 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.5E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS06315 625ebf8e46d4ae74b1f2b44365d65fd1 70 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.5E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS06315 625ebf8e46d4ae74b1f2b44365d65fd1 70 SUPERFAMILY SSF46785 2 59 4.24E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS29250 671f159f27b8539b82db2c6384380db4 290 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 19 290 1.4E-5 T 29-03-2018 IPR020803 Polyketide synthase, methyltransferase domain THSYN_RS29250 671f159f27b8539b82db2c6384380db4 290 SUPERFAMILY SSF53335 41 284 5.21E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS29250 671f159f27b8539b82db2c6384380db4 290 Gene3D G3DSA:3.40.50.150 26 255 4.8E-31 T 29-03-2018 THSYN_RS29250 671f159f27b8539b82db2c6384380db4 290 Pfam PF08241 Methyltransferase domain 75 174 8.4E-18 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THSYN_RS27730 01ee426720fbbf7b4fe1c24223e6d32b 318 Pfam PF10016 Predicted secreted protein (DUF2259) 113 312 2.7E-30 T 29-03-2018 IPR018725 Protein of unknown function DUF2259, secreted THSYN_RS05870 d85342e97b6e57da3dae2f071638926b 697 Gene3D G3DSA:3.40.50.10140 1 112 2.3E-20 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS05870 d85342e97b6e57da3dae2f071638926b 697 Pfam PF12770 CHAT domain 308 543 3.2E-17 T 29-03-2018 IPR024983 CHAT domain THSYN_RS05870 d85342e97b6e57da3dae2f071638926b 697 Gene3D G3DSA:3.40.50.1460 268 555 1.7E-22 T 29-03-2018 THSYN_RS05870 d85342e97b6e57da3dae2f071638926b 697 SUPERFAMILY SSF52200 2 101 2.22E-19 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS05870 d85342e97b6e57da3dae2f071638926b 697 SMART SM00255 1 139 4.4E-5 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS05870 d85342e97b6e57da3dae2f071638926b 697 Pfam PF13676 TIR domain 4 102 5.2E-19 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS32115 7becca3b94faaba95732b655a4a936b6 89 Pfam PF03683 Uncharacterised protein family (UPF0175) 8 76 2.7E-22 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS04905 ade8bd3f70ef3061f0a9b8f82b928f1d 121 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 11 51 7.0E-10 T 29-03-2018 THSYN_RS04905 ade8bd3f70ef3061f0a9b8f82b928f1d 121 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 10 67 3.0E-10 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS04905 ade8bd3f70ef3061f0a9b8f82b928f1d 121 Gene3D G3DSA:3.40.1620.10 3 68 6.9E-13 T 29-03-2018 THSYN_RS04905 ade8bd3f70ef3061f0a9b8f82b928f1d 121 SUPERFAMILY SSF143120 10 67 3.53E-9 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS23320 1869cd84235daf77b1bba8b0830c57d9 331 Gene3D G3DSA:3.40.390.10 126 311 3.2E-8 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 THSYN_RS23320 1869cd84235daf77b1bba8b0830c57d9 331 Pfam PF01471 Putative peptidoglycan binding domain 9 64 2.0E-4 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS23320 1869cd84235daf77b1bba8b0830c57d9 331 Gene3D G3DSA:1.10.101.10 5 83 3.8E-8 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS29000 e209ad295f9645bc05248bedcea2ef42 313 Pfam PF00535 Glycosyl transferase family 2 9 128 1.8E-33 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS29000 e209ad295f9645bc05248bedcea2ef42 313 Gene3D G3DSA:3.90.550.10 1 233 2.9E-53 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS29000 e209ad295f9645bc05248bedcea2ef42 313 SUPERFAMILY SSF53448 6 207 9.64E-56 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS23855 7bb68fefc30a54488b5f8e43224e7781 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 29-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23855 7bb68fefc30a54488b5f8e43224e7781 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.443 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS23855 7bb68fefc30a54488b5f8e43224e7781 179 SUPERFAMILY SSF55282 3 179 5.42E-76 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23855 7bb68fefc30a54488b5f8e43224e7781 179 Pfam PF00281 Ribosomal protein L5 24 80 2.1E-25 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23855 7bb68fefc30a54488b5f8e43224e7781 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 7.7E-42 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23855 7bb68fefc30a54488b5f8e43224e7781 179 PIRSF PIRSF002161 1 179 1.3E-62 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23855 7bb68fefc30a54488b5f8e43224e7781 179 Gene3D G3DSA:3.30.1440.10 1 179 1.2E-74 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS04035 283c8434230c2df06b861ef8db015b57 94 Gene3D G3DSA:3.10.20.30 1 94 4.8E-21 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS04035 283c8434230c2df06b861ef8db015b57 94 SUPERFAMILY SSF54292 4 92 8.52E-22 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS04035 283c8434230c2df06b861ef8db015b57 94 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 85 7.9E-14 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS04035 283c8434230c2df06b861ef8db015b57 94 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THSYN_RS25025 562b315b0526d7286c7fb7f6903d71c1 292 Pfam PF14261 Domain of unknown function (DUF4351) 231 281 3.7E-6 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS25025 562b315b0526d7286c7fb7f6903d71c1 292 Pfam PF11103 Protein of unknown function (DUF2887) 3 201 1.4E-36 T 29-03-2018 IPR022573 Protein of unknown function DUF2887 THSYN_RS29760 212789544784d04ce393b7d217a4674b 343 SUPERFAMILY SSF46785 21 100 3.05E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS29760 212789544784d04ce393b7d217a4674b 343 SUPERFAMILY SSF53850 113 318 1.71E-43 T 29-03-2018 THSYN_RS29760 212789544784d04ce393b7d217a4674b 343 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 83 1.3E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS29760 212789544784d04ce393b7d217a4674b 343 Gene3D G3DSA:3.40.190.10 111 198 2.2E-17 T 29-03-2018 THSYN_RS29760 212789544784d04ce393b7d217a4674b 343 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 61 7.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS29760 212789544784d04ce393b7d217a4674b 343 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 61 72 7.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS29760 212789544784d04ce393b7d217a4674b 343 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS29760 212789544784d04ce393b7d217a4674b 343 Gene3D G3DSA:1.10.10.10 19 105 3.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS29760 212789544784d04ce393b7d217a4674b 343 Gene3D G3DSA:3.40.190.10 199 289 1.3E-22 T 29-03-2018 THSYN_RS29760 212789544784d04ce393b7d217a4674b 343 Pfam PF03466 LysR substrate binding domain 112 314 6.7E-50 T 29-03-2018 IPR005119 LysR, substrate-binding THSYN_RS08210 adab7277ac20600ad40ab8bab61cc0e7 190 Gene3D G3DSA:2.40.50.140 125 185 0.0076 T 29-03-2018 THSYN_RS05090 49e222ecfb85ca08d93e1b8d6855c9af 359 SUPERFAMILY SSF52540 3 245 6.62E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05090 49e222ecfb85ca08d93e1b8d6855c9af 359 Pfam PF00005 ABC transporter 18 164 2.7E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS05090 49e222ecfb85ca08d93e1b8d6855c9af 359 Pfam PF12857 TOBE-like domain 290 348 1.1E-7 T 29-03-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 THSYN_RS05090 49e222ecfb85ca08d93e1b8d6855c9af 359 SUPERFAMILY SSF50331 240 353 1.02E-6 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal THSYN_RS05090 49e222ecfb85ca08d93e1b8d6855c9af 359 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 242 2.3E-116 T 29-03-2018 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 THSYN_RS05090 49e222ecfb85ca08d93e1b8d6855c9af 359 Gene3D G3DSA:3.40.50.300 1 261 3.0E-75 T 29-03-2018 THSYN_RS05090 49e222ecfb85ca08d93e1b8d6855c9af 359 SMART SM00382 27 214 6.2E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS05090 49e222ecfb85ca08d93e1b8d6855c9af 359 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS24070 89147a2d1bf5652092d628639fef4d1f 282 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 222 241 1.2E-24 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THSYN_RS24070 89147a2d1bf5652092d628639fef4d1f 282 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 75 91 1.2E-24 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THSYN_RS24070 89147a2d1bf5652092d628639fef4d1f 282 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 139 151 1.2E-24 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THSYN_RS24070 89147a2d1bf5652092d628639fef4d1f 282 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 60 261 3.1E-50 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THSYN_RS24070 89147a2d1bf5652092d628639fef4d1f 282 ProSitePatterns PS00760 Signal peptidases I lysine active site. 141 153 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 THSYN_RS24070 89147a2d1bf5652092d628639fef4d1f 282 ProSitePatterns PS00761 Signal peptidases I signature 3. 227 240 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 THSYN_RS24070 89147a2d1bf5652092d628639fef4d1f 282 Pfam PF00717 Peptidase S24-like 81 163 9.0E-23 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THSYN_RS24070 89147a2d1bf5652092d628639fef4d1f 282 ProSitePatterns PS00501 Signal peptidases I serine active site. 84 91 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 THSYN_RS24070 89147a2d1bf5652092d628639fef4d1f 282 SUPERFAMILY SSF51306 73 278 3.92E-68 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THSYN_RS24070 89147a2d1bf5652092d628639fef4d1f 282 Gene3D G3DSA:2.10.109.10 71 277 1.6E-55 T 29-03-2018 THSYN_RS24070 89147a2d1bf5652092d628639fef4d1f 282 Pfam PF10502 Signal peptidase, peptidase S26 220 259 2.1E-4 T 29-03-2018 IPR019533 Peptidase S26 THSYN_RS32625 0a747a4f33aaec554e498ff8d4d4ca15 227 Pfam PF00581 Rhodanese-like domain 97 213 2.0E-7 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS32625 0a747a4f33aaec554e498ff8d4d4ca15 227 TIGRFAM TIGR03865 PQQ_CXXCW: PQQ-dependent catabolism-associated CXXCW motif protein 63 223 6.7E-62 T 29-03-2018 IPR022376 PQQ-dependent catabolism-associated CXXCW motif THSYN_RS32625 0a747a4f33aaec554e498ff8d4d4ca15 227 Gene3D G3DSA:3.40.250.10 88 227 1.3E-18 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS32625 0a747a4f33aaec554e498ff8d4d4ca15 227 SUPERFAMILY SSF52821 93 223 5.37E-22 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS30425 1c4c0b6a5321d7cdf42481cf0dba0ce7 347 Pfam PF06586 TraK protein 109 330 7.9E-23 T 29-03-2018 IPR010563 Pilus assembly TraK THSYN_RS06530 5bef1ec7a309e6aee061006973b844f6 259 SUPERFAMILY SSF48613 109 255 5.78E-8 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 THSYN_RS06530 5bef1ec7a309e6aee061006973b844f6 259 Gene3D G3DSA:1.20.910.10 5 258 6.1E-40 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 THSYN_RS06530 5bef1ec7a309e6aee061006973b844f6 259 Pfam PF11251 Protein of unknown function (DUF3050) 16 249 8.7E-82 T 29-03-2018 IPR024423 Protein of unknown function DUF3050 THSYN_RS00140 48524ddb6a7dea4326b201c308c606f5 184 Gene3D G3DSA:3.40.50.880 1 182 6.1E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS00140 48524ddb6a7dea4326b201c308c606f5 184 Pfam PF01965 DJ-1/PfpI family 3 165 2.3E-43 T 29-03-2018 IPR002818 DJ-1/PfpI THSYN_RS00140 48524ddb6a7dea4326b201c308c606f5 184 SUPERFAMILY SSF52317 1 182 2.04E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS00140 48524ddb6a7dea4326b201c308c606f5 184 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 4 177 6.2E-52 T 29-03-2018 IPR006287 Protein DJ-1 THSYN_RS11160 678c3fa18502106e45cc76090c91c8b6 175 Gene3D G3DSA:1.20.1290.10 13 175 9.9E-16 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 THSYN_RS11160 678c3fa18502106e45cc76090c91c8b6 175 SUPERFAMILY SSF69118 37 174 2.75E-15 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 THSYN_RS05755 52c89515c7421ddf3a7e4009289f6397 512 Gene3D G3DSA:3.90.640.20 391 508 3.6E-4 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 THSYN_RS05755 52c89515c7421ddf3a7e4009289f6397 512 Pfam PF07007 Lysozyme inhibitor LprI 62 140 9.7E-7 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal THSYN_RS20320 344691a80e0b470383aa12e5661c4342 104 Pfam PF06463 Molybdenum Cofactor Synthesis C 1 70 7.0E-14 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 THSYN_RS20320 344691a80e0b470383aa12e5661c4342 104 Gene3D G3DSA:3.20.20.70 1 81 2.3E-7 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS10130 95e3a321180067b1377d66a8a72b6bea 130 SUPERFAMILY SSF54593 6 122 1.19E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THSYN_RS10130 95e3a321180067b1377d66a8a72b6bea 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 120 5.1E-14 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THSYN_RS10130 95e3a321180067b1377d66a8a72b6bea 130 Gene3D G3DSA:3.10.180.10 1 130 1.7E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THSYN_RS04955 c5d9f71d8cf7c0a735d00a1243d71a02 95 SUPERFAMILY SSF81901 31 94 8.24E-20 T 29-03-2018 THSYN_RS04955 c5d9f71d8cf7c0a735d00a1243d71a02 95 Gene3D G3DSA:2.60.40.1180 20 95 7.9E-24 T 29-03-2018 THSYN_RS04955 c5d9f71d8cf7c0a735d00a1243d71a02 95 SMART SM00671 40 75 6.0E-13 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS04955 c5d9f71d8cf7c0a735d00a1243d71a02 95 Pfam PF08238 Sel1 repeat 79 94 5.7 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS04955 c5d9f71d8cf7c0a735d00a1243d71a02 95 Pfam PF08238 Sel1 repeat 40 75 2.3E-11 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS08330 71f5c50a36e449bf0e8dcb9cd7bd52d9 262 PIRSF PIRSF006648 5 259 3.8E-24 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THSYN_RS08330 71f5c50a36e449bf0e8dcb9cd7bd52d9 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 64 86 2.9E-6 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THSYN_RS08330 71f5c50a36e449bf0e8dcb9cd7bd52d9 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 108 133 2.9E-6 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THSYN_RS08330 71f5c50a36e449bf0e8dcb9cd7bd52d9 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 182 201 2.9E-6 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THSYN_RS08330 71f5c50a36e449bf0e8dcb9cd7bd52d9 262 Pfam PF01061 ABC-2 type transporter 15 224 2.7E-35 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 THSYN_RS01065 213e17be820b083f5d5c35a73c6cd4d3 364 SUPERFAMILY SSF55620 238 355 1.89E-20 T 29-03-2018 THSYN_RS01065 213e17be820b083f5d5c35a73c6cd4d3 364 SUPERFAMILY SSF55620 11 95 2.0E-7 T 29-03-2018 THSYN_RS01065 213e17be820b083f5d5c35a73c6cd4d3 364 Gene3D G3DSA:3.30.479.10 8 115 2.6E-6 T 29-03-2018 THSYN_RS01065 213e17be820b083f5d5c35a73c6cd4d3 364 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 123 236 3.4E-22 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 THSYN_RS01065 213e17be820b083f5d5c35a73c6cd4d3 364 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 241 352 1.1E-17 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 THSYN_RS01065 213e17be820b083f5d5c35a73c6cd4d3 364 Gene3D G3DSA:3.30.479.10 237 354 4.5E-21 T 29-03-2018 THSYN_RS01065 213e17be820b083f5d5c35a73c6cd4d3 364 Gene3D G3DSA:3.30.479.10 119 236 7.0E-25 T 29-03-2018 THSYN_RS01065 213e17be820b083f5d5c35a73c6cd4d3 364 SUPERFAMILY SSF55620 122 235 4.0E-27 T 29-03-2018 THSYN_RS13735 fa4ad33060c473fb0ffa8ab48e8d1b2f 306 Pfam PF05685 Putative restriction endonuclease 42 208 4.8E-14 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS13735 fa4ad33060c473fb0ffa8ab48e8d1b2f 306 SUPERFAMILY SSF52980 30 214 3.7E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS13735 fa4ad33060c473fb0ffa8ab48e8d1b2f 306 Gene3D G3DSA:3.90.1570.10 27 214 1.1E-20 T 29-03-2018 THSYN_RS18020 5fc8d0cf0761a1785d622be4cbf8eaa1 192 Pfam PF01292 Prokaryotic cytochrome b561 6 175 2.8E-31 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THSYN_RS18020 5fc8d0cf0761a1785d622be4cbf8eaa1 192 SUPERFAMILY SSF81342 2 181 5.41E-38 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THSYN_RS18020 5fc8d0cf0761a1785d622be4cbf8eaa1 192 Gene3D G3DSA:1.20.950.20 1 190 3.4E-36 T 29-03-2018 THSYN_RS06655 983f77c47cb30096dbf9943bb6dbd570 798 SUPERFAMILY SSF82689 686 784 5.89E-27 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 THSYN_RS06655 983f77c47cb30096dbf9943bb6dbd570 798 Pfam PF00924 Mechanosensitive ion channel 577 773 4.0E-50 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THSYN_RS06655 983f77c47cb30096dbf9943bb6dbd570 798 Gene3D G3DSA:2.30.30.60 636 685 5.9E-13 T 29-03-2018 THSYN_RS06655 983f77c47cb30096dbf9943bb6dbd570 798 SUPERFAMILY SSF82861 535 617 6.8E-10 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 THSYN_RS06655 983f77c47cb30096dbf9943bb6dbd570 798 SUPERFAMILY SSF50182 619 684 4.58E-16 T 29-03-2018 IPR010920 LSM domain THSYN_RS06655 983f77c47cb30096dbf9943bb6dbd570 798 Gene3D G3DSA:3.30.70.100 686 779 2.0E-22 T 29-03-2018 THSYN_RS02825 c4cf64ef2aa905b1a3bf0a0d9982deb6 316 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 306 8.5E-82 T 29-03-2018 IPR007296 Domain of unknown function DUF403 THSYN_RS01335 682efbf8c31c80ab9cf589968939816a 190 SUPERFAMILY SSF50630 47 182 1.02E-25 T 29-03-2018 IPR021109 Aspartic peptidase domain THSYN_RS01335 682efbf8c31c80ab9cf589968939816a 190 Pfam PF05618 Putative ATP-dependant zinc protease 47 183 4.1E-18 T 29-03-2018 THSYN_RS01335 682efbf8c31c80ab9cf589968939816a 190 Gene3D G3DSA:2.40.70.10 45 175 9.2E-27 T 29-03-2018 IPR021109 Aspartic peptidase domain THSYN_RS23470 84206cdd86b1ea5b670c7149f942c11b 296 Pfam PF04085 rod shape-determining protein MreC 126 269 9.4E-36 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 THSYN_RS23470 84206cdd86b1ea5b670c7149f942c11b 296 PIRSF PIRSF038471 2 282 1.1E-72 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 THSYN_RS23470 84206cdd86b1ea5b670c7149f942c11b 296 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 5 275 3.5E-61 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 THSYN_RS13215 68c46612a914cfc4ba8b095e423c274f 136 SMART SM00748 14 126 2.9E-18 T 29-03-2018 IPR007842 HEPN domain THSYN_RS13215 68c46612a914cfc4ba8b095e423c274f 136 Gene3D G3DSA:1.20.120.330 7 135 9.7E-29 T 29-03-2018 THSYN_RS13215 68c46612a914cfc4ba8b095e423c274f 136 SUPERFAMILY SSF81593 9 131 6.28E-31 T 29-03-2018 THSYN_RS13215 68c46612a914cfc4ba8b095e423c274f 136 Pfam PF05168 HEPN domain 11 131 1.2E-25 T 29-03-2018 IPR007842 HEPN domain THSYN_RS25510 b10c640f495b70603851693dc97f4081 264 Pfam PF01925 Sulfite exporter TauE/SafE 10 261 3.6E-54 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 THSYN_RS32480 effeb27614a7c641994de5a1dbd55366 204 Pfam PF13460 NAD(P)H-binding 7 194 3.3E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS32480 effeb27614a7c641994de5a1dbd55366 204 SUPERFAMILY SSF51735 1 203 4.5E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS32480 effeb27614a7c641994de5a1dbd55366 204 Gene3D G3DSA:3.40.50.720 1 200 3.6E-33 T 29-03-2018 THSYN_RS00425 bdbf4a6d5e122df13d14230379ac58a4 999 SUPERFAMILY SSF52490 105 192 1.44E-8 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS00425 bdbf4a6d5e122df13d14230379ac58a4 999 SUPERFAMILY SSF52490 3 60 1.44E-8 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS00425 bdbf4a6d5e122df13d14230379ac58a4 999 Pfam PF13809 Tubulin like 5 346 3.1E-72 T 29-03-2018 IPR025904 Tubulin-like THSYN_RS00425 bdbf4a6d5e122df13d14230379ac58a4 999 Gene3D G3DSA:3.40.50.1440 2 294 2.9E-18 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS06970 27793ea4894f1a30afaca6fe3afaadb9 159 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 6 65 5.1E-28 T 29-03-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal THSYN_RS06970 27793ea4894f1a30afaca6fe3afaadb9 159 Pfam PF05233 PHB accumulation regulatory domain 70 108 9.1E-17 T 29-03-2018 IPR007897 PHB accumulation regulatory THSYN_RS06970 27793ea4894f1a30afaca6fe3afaadb9 159 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 5 110 2.6E-48 T 29-03-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 THSYN_RS07510 9a27f94b984e030b249416438da4448e 371 Gene3D G3DSA:3.40.630.10 134 367 3.3E-39 T 29-03-2018 THSYN_RS07510 9a27f94b984e030b249416438da4448e 371 Pfam PF04389 Peptidase family M28 206 316 2.0E-26 T 29-03-2018 IPR007484 Peptidase M28 THSYN_RS07510 9a27f94b984e030b249416438da4448e 371 SUPERFAMILY SSF53187 146 360 1.42E-45 T 29-03-2018 THSYN_RS00050 1e7d794f5817dc6f39cace952b0858cc 169 Pfam PF13511 Domain of unknown function (DUF4124) 13 65 2.5E-11 T 29-03-2018 IPR025392 Domain of unknown function DUF4124 THSYN_RS27545 96fea2bd6c3c54af2c0bfad4821c3994 109 Pfam PF01909 Nucleotidyltransferase domain 19 76 4.1E-10 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS27545 96fea2bd6c3c54af2c0bfad4821c3994 109 SUPERFAMILY SSF81301 5 106 1.48E-18 T 29-03-2018 THSYN_RS27545 96fea2bd6c3c54af2c0bfad4821c3994 109 Gene3D G3DSA:3.30.460.10 2 105 2.6E-17 T 29-03-2018 THSYN_RS15990 9c4e29a84ad2cd1f6c7f5ab21dbd9d1c 483 SUPERFAMILY SSF116734 50 215 9.32E-19 T 29-03-2018 THSYN_RS15990 9c4e29a84ad2cd1f6c7f5ab21dbd9d1c 483 Gene3D G3DSA:3.90.220.20 260 417 7.7E-16 T 29-03-2018 THSYN_RS15990 9c4e29a84ad2cd1f6c7f5ab21dbd9d1c 483 Gene3D G3DSA:3.90.220.20 7 206 1.0E-18 T 29-03-2018 THSYN_RS15990 9c4e29a84ad2cd1f6c7f5ab21dbd9d1c 483 SUPERFAMILY SSF116734 270 452 2.13E-17 T 29-03-2018 THSYN_RS30685 380ae78eeaf500e82556e919e7a40670 397 Gene3D G3DSA:1.20.1250.20 6 193 1.7E-12 T 29-03-2018 THSYN_RS30685 380ae78eeaf500e82556e919e7a40670 397 Gene3D G3DSA:1.20.1250.20 205 396 9.8E-24 T 29-03-2018 THSYN_RS30685 380ae78eeaf500e82556e919e7a40670 397 SUPERFAMILY SSF103473 12 391 1.31E-36 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS30685 380ae78eeaf500e82556e919e7a40670 397 Pfam PF07690 Major Facilitator Superfamily 222 394 1.2E-8 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THSYN_RS09800 73d3f3995266c463effcdf279d53a780 692 Pfam PF02384 N-6 DNA Methylase 602 644 1.2E-4 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS09800 73d3f3995266c463effcdf279d53a780 692 Pfam PF02384 N-6 DNA Methylase 157 438 3.4E-74 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS09800 73d3f3995266c463effcdf279d53a780 692 Gene3D G3DSA:3.40.50.150 178 644 1.4E-59 T 29-03-2018 THSYN_RS09800 73d3f3995266c463effcdf279d53a780 692 SUPERFAMILY SSF53335 78 446 1.99E-107 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS09800 73d3f3995266c463effcdf279d53a780 692 SUPERFAMILY SSF53335 606 675 1.99E-107 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS09800 73d3f3995266c463effcdf279d53a780 692 SUPERFAMILY SSF53335 8 48 1.99E-107 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS09800 73d3f3995266c463effcdf279d53a780 692 Pfam PF12161 HsdM N-terminal domain 9 131 2.2E-17 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS09800 73d3f3995266c463effcdf279d53a780 692 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 180 196 1.0E-16 T 29-03-2018 THSYN_RS09800 73d3f3995266c463effcdf279d53a780 692 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 282 294 1.0E-16 T 29-03-2018 THSYN_RS09800 73d3f3995266c463effcdf279d53a780 692 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 331 355 1.0E-16 T 29-03-2018 THSYN_RS09800 73d3f3995266c463effcdf279d53a780 692 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 203 217 1.0E-16 T 29-03-2018 THSYN_RS09800 73d3f3995266c463effcdf279d53a780 692 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 285 291 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS14110 50c03e6d6e237f44b1f4e296417a24f2 394 Gene3D G3DSA:1.10.3680.10 308 361 0.098 T 29-03-2018 IPR029024 TerB-like THSYN_RS08115 9db164a461ed3835e556cc568556c644 97 Gene3D G3DSA:3.30.70.240 1 95 2.0E-23 T 29-03-2018 THSYN_RS08115 9db164a461ed3835e556cc568556c644 97 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 4 88 15.216 T 29-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THSYN_RS08115 9db164a461ed3835e556cc568556c644 97 SUPERFAMILY SSF143430 4 70 1.28E-21 T 29-03-2018 THSYN_RS08115 9db164a461ed3835e556cc568556c644 97 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 4 71 1.8E-11 T 29-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THSYN_RS08115 9db164a461ed3835e556cc568556c644 97 Pfam PF09827 CRISPR associated protein Cas2 5 69 1.4E-16 T 29-03-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 THSYN_RS08130 c826d69f245deea247d3b6529f3b5f4d 379 TIGRFAM TIGR02570 cas7_GSU0053: CRISPR-associated protein GSU0053/csb1, Dpsyc system 23 189 3.6E-38 T 29-03-2018 IPR013403 CRISPR-associated protein GSU0053 THSYN_RS08130 c826d69f245deea247d3b6529f3b5f4d 379 Pfam PF09617 CRISPR-associated protein GSU0053 (Cas_GSU0053) 25 183 1.5E-36 T 29-03-2018 IPR013403 CRISPR-associated protein GSU0053 THSYN_RS30290 d7f34a0fe58665fdaeff7c7caa2298b3 146 SMART SM00411 39 129 4.0E-15 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS30290 d7f34a0fe58665fdaeff7c7caa2298b3 146 Gene3D G3DSA:4.10.520.10 37 136 5.6E-17 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS30290 d7f34a0fe58665fdaeff7c7caa2298b3 146 SUPERFAMILY SSF47729 39 129 1.21E-15 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS30290 d7f34a0fe58665fdaeff7c7caa2298b3 146 Pfam PF00216 Bacterial DNA-binding protein 39 128 5.4E-15 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS15320 3bf4945dedf8f88d79f7c64b3eed9610 126 Pfam PF13635 Domain of unknown function (DUF4143) 1 71 6.4E-15 T 29-03-2018 IPR025420 Domain of unknown function DUF4143 THSYN_RS15705 96e8b372b756d29f197ecdf4f9015fa7 649 Gene3D G3DSA:1.10.287.130 405 482 0.0018 T 29-03-2018 THSYN_RS15705 96e8b372b756d29f197ecdf4f9015fa7 649 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 534 638 1.4E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS15705 96e8b372b756d29f197ecdf4f9015fa7 649 SMART SM00387 533 642 1.8E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS15705 96e8b372b756d29f197ecdf4f9015fa7 649 Gene3D G3DSA:3.30.565.10 493 643 3.2E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS15705 96e8b372b756d29f197ecdf4f9015fa7 649 SUPERFAMILY SSF55874 504 642 3.27E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS21550 7c391da4c062099349b344524664b60e 79 Pfam PF13711 Domain of unknown function (DUF4160) 11 74 3.5E-12 T 29-03-2018 IPR025427 Protein of unknown function DUF4160 THSYN_RS11405 8417cc72dc665c11d53f0810ea850f82 125 Gene3D G3DSA:3.30.420.130 1 108 2.0E-17 T 29-03-2018 THSYN_RS11405 8417cc72dc665c11d53f0810ea850f82 125 SUPERFAMILY SSF53146 1 103 8.76E-18 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THSYN_RS21555 62d0e098aecc6ca95aada78155891298 87 Pfam PF10387 Protein of unknown function (DUF2442) 9 74 4.0E-12 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS16470 4d8cd8f107845f668c4e16c4e2b3a4d0 359 Pfam PF13489 Methyltransferase domain 149 289 1.8E-23 T 29-03-2018 THSYN_RS16470 4d8cd8f107845f668c4e16c4e2b3a4d0 359 Gene3D G3DSA:3.40.50.150 71 347 1.6E-33 T 29-03-2018 THSYN_RS16470 4d8cd8f107845f668c4e16c4e2b3a4d0 359 SUPERFAMILY SSF53335 137 298 1.28E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS00865 023d0c390dfa8c7dee00ac7ffb54481b 273 Pfam PF13242 HAD-hyrolase-like 184 239 1.1E-18 T 29-03-2018 THSYN_RS00865 023d0c390dfa8c7dee00ac7ffb54481b 273 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 10 233 1.3E-37 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA THSYN_RS00865 023d0c390dfa8c7dee00ac7ffb54481b 273 Pfam PF13344 Haloacid dehalogenase-like hydrolase 9 106 1.6E-17 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA THSYN_RS00865 023d0c390dfa8c7dee00ac7ffb54481b 273 SUPERFAMILY SSF56784 7 259 7.5E-51 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS00865 023d0c390dfa8c7dee00ac7ffb54481b 273 Gene3D G3DSA:3.40.50.1000 1 264 1.1E-29 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS01720 2be4f54d25f9ac31efda89b530767aa6 289 Gene3D G3DSA:3.40.50.1820 2 284 2.3E-8 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS01720 2be4f54d25f9ac31efda89b530767aa6 289 SUPERFAMILY SSF53474 149 249 4.3E-8 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS18510 ccf999fd704b88053ed7952674428b78 232 Pfam PF09414 RNA ligase 39 200 4.8E-28 T 29-03-2018 IPR021122 RNA ligase domain, REL/Rln2 THSYN_RS18510 ccf999fd704b88053ed7952674428b78 232 SUPERFAMILY SSF56091 7 225 2.88E-34 T 29-03-2018 THSYN_RS09505 fecd751fea2ae4daa3208bf0c0809f0a 402 Pfam PF12838 4Fe-4S dicluster domain 297 350 9.9E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS09505 fecd751fea2ae4daa3208bf0c0809f0a 402 SUPERFAMILY SSF54862 292 357 3.02E-13 T 29-03-2018 THSYN_RS09505 fecd751fea2ae4daa3208bf0c0809f0a 402 Gene3D G3DSA:3.30.70.20 281 341 6.0E-12 T 29-03-2018 THSYN_RS09505 fecd751fea2ae4daa3208bf0c0809f0a 402 SUPERFAMILY SSF46785 54 105 2.41E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS09505 fecd751fea2ae4daa3208bf0c0809f0a 402 Gene3D G3DSA:1.10.10.10 7 260 2.0E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS09505 fecd751fea2ae4daa3208bf0c0809f0a 402 Gene3D G3DSA:3.30.70.20 342 369 2.3E-5 T 29-03-2018 THSYN_RS00930 74eb0cbcecf54b6fa0cc6909e788f7b1 67 Gene3D G3DSA:1.10.1220.10 4 50 8.6E-7 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS27085 5762aa4612e85abbb6e812fa53b28e4e 94 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 7 81 5.0E-12 T 29-03-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THSYN_RS28025 2de880ce76e55e35fb15fdb5594d6916 151 Gene3D G3DSA:1.10.10.10 102 151 1.9E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS28025 2de880ce76e55e35fb15fdb5594d6916 151 Gene3D G3DSA:1.10.10.10 56 100 3.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS28025 2de880ce76e55e35fb15fdb5594d6916 151 Hamap MF_01114 Regulatory protein RecX [recX]. 2 151 12.272 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 THSYN_RS28025 2de880ce76e55e35fb15fdb5594d6916 151 Gene3D G3DSA:1.10.10.10 9 53 1.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS28025 2de880ce76e55e35fb15fdb5594d6916 151 Pfam PF02631 RecX family 32 149 2.6E-23 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 THSYN_RS28940 72e2ef34ff961f236aae4797262edec8 314 SUPERFAMILY SSF52540 32 246 3.66E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS28940 72e2ef34ff961f236aae4797262edec8 314 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 61 221 4.9E-27 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THSYN_RS28940 72e2ef34ff961f236aae4797262edec8 314 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 34 243 1.5E-75 T 29-03-2018 IPR004392 Hydrogenase accessory protein HypB GO:0006461|GO:0016151 THSYN_RS28940 72e2ef34ff961f236aae4797262edec8 314 Gene3D G3DSA:3.40.50.300 59 223 3.6E-20 T 29-03-2018 THSYN_RS13050 32d13f77f1f99755bf601e33071e21d8 323 Gene3D G3DSA:3.40.50.1980 124 298 2.6E-35 T 29-03-2018 THSYN_RS13050 32d13f77f1f99755bf601e33071e21d8 323 SUPERFAMILY SSF53807 1 319 7.46E-48 T 29-03-2018 THSYN_RS13050 32d13f77f1f99755bf601e33071e21d8 323 Gene3D G3DSA:3.40.50.1980 1 123 6.3E-18 T 29-03-2018 THSYN_RS13050 32d13f77f1f99755bf601e33071e21d8 323 Pfam PF01497 Periplasmic binding protein 64 251 2.7E-13 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 THSYN_RS22865 6ae65cd2a351b1fac81c521232de86e7 424 SUPERFAMILY SSF53720 12 423 1.14E-116 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THSYN_RS22865 6ae65cd2a351b1fac81c521232de86e7 424 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 12 423 41.569 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THSYN_RS22865 6ae65cd2a351b1fac81c521232de86e7 424 PIRSF PIRSF000151 6 424 8.5E-173 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 THSYN_RS22865 6ae65cd2a351b1fac81c521232de86e7 424 Gene3D G3DSA:3.40.605.10 249 424 3.8E-45 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THSYN_RS22865 6ae65cd2a351b1fac81c521232de86e7 424 Pfam PF00171 Aldehyde dehydrogenase family 18 288 1.0E-11 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THSYN_RS22865 6ae65cd2a351b1fac81c521232de86e7 424 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 20 413 2.4E-142 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THSYN_RS22865 6ae65cd2a351b1fac81c521232de86e7 424 Gene3D G3DSA:3.40.605.10 9 248 9.5E-42 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THSYN_RS14325 425f4e54b650a20b1e84dc33e89f02f9 127 Pfam PF06953 Arsenical resistance operon trans-acting repressor ArsD 1 127 1.1E-42 T 29-03-2018 IPR010712 Arsenical-resistance operon trans-acting repressor ArsD GO:0003677|GO:0045892|GO:0046685 THSYN_RS25625 2ba6df0ed5d66f269b65cfe5387885ab 963 Pfam PF03993 Domain of Unknown Function (DUF349) 618 676 1.1E-5 T 29-03-2018 IPR007139 Protein of unknown function DUF349 THSYN_RS25625 2ba6df0ed5d66f269b65cfe5387885ab 963 Pfam PF03993 Domain of Unknown Function (DUF349) 685 756 4.2E-15 T 29-03-2018 IPR007139 Protein of unknown function DUF349 THSYN_RS25625 2ba6df0ed5d66f269b65cfe5387885ab 963 Pfam PF03993 Domain of Unknown Function (DUF349) 533 607 3.2E-8 T 29-03-2018 IPR007139 Protein of unknown function DUF349 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 17 33 3.3E-54 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 201 220 3.3E-54 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 110 126 3.3E-54 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 33 54 3.3E-54 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 141 155 3.3E-54 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 251 270 3.3E-54 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 296 322 3.3E-54 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 77 90 3.3E-54 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 164 183 3.3E-54 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 PIRSF PIRSF019574 3 352 8.5E-119 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 Pfam PF13416 Bacterial extracellular solute-binding protein 29 315 1.8E-27 T 29-03-2018 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 Gene3D G3DSA:3.40.190.10 6 168 4.4E-22 T 29-03-2018 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 SUPERFAMILY SSF53850 11 351 2.79E-90 T 29-03-2018 THSYN_RS07925 48966dac536a42db8f72f380d098ddbf 352 Gene3D G3DSA:3.40.190.10 169 327 1.3E-17 T 29-03-2018 THSYN_RS32940 81b824c8f769978c544cd113c9ddfc69 318 Gene3D G3DSA:2.40.160.10 105 314 1.5E-4 T 29-03-2018 THSYN_RS32940 81b824c8f769978c544cd113c9ddfc69 318 SUPERFAMILY SSF56935 148 296 4.35E-5 T 29-03-2018 THSYN_RS32940 81b824c8f769978c544cd113c9ddfc69 318 Pfam PF13557 Putative MetA-pathway of phenol degradation 77 314 2.4E-75 T 29-03-2018 IPR025737 MetA-pathway of phenol degradation, putative THSYN_RS07165 1011a76efef722d17aa85cc52e1c4e70 269 SUPERFAMILY SSF52980 19 165 1.82E-9 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS07165 1011a76efef722d17aa85cc52e1c4e70 269 Gene3D G3DSA:3.90.1570.10 11 164 1.4E-7 T 29-03-2018 THSYN_RS07165 1011a76efef722d17aa85cc52e1c4e70 269 Pfam PF05685 Putative restriction endonuclease 20 160 5.7E-7 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS26815 377351200e55f2f9aa315213742b861c 189 SUPERFAMILY SSF51182 7 184 6.43E-62 T 29-03-2018 IPR011051 RmlC-like cupin domain THSYN_RS26815 377351200e55f2f9aa315213742b861c 189 Gene3D G3DSA:2.60.120.10 1 187 3.2E-60 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS26815 377351200e55f2f9aa315213742b861c 189 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 12 181 2.6E-56 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THSYN_RS26815 377351200e55f2f9aa315213742b861c 189 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 6 178 5.0E-58 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THSYN_RS12315 81116577682b33cbd934202347a351b0 402 Pfam PF02661 Fic/DOC family 118 228 3.0E-18 T 29-03-2018 IPR003812 Fido domain THSYN_RS12315 81116577682b33cbd934202347a351b0 402 SUPERFAMILY SSF140931 93 298 9.02E-33 T 29-03-2018 IPR003812 Fido domain THSYN_RS12315 81116577682b33cbd934202347a351b0 402 Gene3D G3DSA:1.10.3290.10 23 311 9.4E-43 T 29-03-2018 IPR003812 Fido domain THSYN_RS10075 4a642c40db2ef314fb4cf45690e141ed 165 SUPERFAMILY SSF54523 51 155 2.09E-9 T 29-03-2018 THSYN_RS10075 4a642c40db2ef314fb4cf45690e141ed 165 Gene3D G3DSA:3.30.700.10 36 148 9.0E-10 T 29-03-2018 THSYN_RS25860 6c391443b75a19a812e50316213820fb 407 Gene3D G3DSA:3.40.710.10 34 407 1.4E-23 T 29-03-2018 THSYN_RS25860 6c391443b75a19a812e50316213820fb 407 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 254 276 2.4E-17 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS25860 6c391443b75a19a812e50316213820fb 407 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 311 325 2.4E-17 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS25860 6c391443b75a19a812e50316213820fb 407 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 69 88 2.4E-17 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS25860 6c391443b75a19a812e50316213820fb 407 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 326 340 2.4E-17 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS25860 6c391443b75a19a812e50316213820fb 407 SUPERFAMILY SSF56601 55 406 7.98E-53 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS25860 6c391443b75a19a812e50316213820fb 407 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 47 177 8.8E-27 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS25860 6c391443b75a19a812e50316213820fb 407 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 220 346 2.2E-19 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS25860 6c391443b75a19a812e50316213820fb 407 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 355 395 1.6E-5 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THSYN_RS22755 04dad1596559d7957a4f41d6f2401359 445 Gene3D G3DSA:3.40.50.2000 2 419 1.2E-22 T 29-03-2018 THSYN_RS22755 04dad1596559d7957a4f41d6f2401359 445 Pfam PF13692 Glycosyl transferases group 1 265 402 2.9E-25 T 29-03-2018 THSYN_RS22755 04dad1596559d7957a4f41d6f2401359 445 SUPERFAMILY SSF53756 29 427 1.52E-27 T 29-03-2018 THSYN_RS31845 a7c4530b313f300eb4edc6d62111fe90 252 Pfam PF07277 SapC 15 233 8.5E-71 T 29-03-2018 IPR010836 SapC THSYN_RS19250 6ad57e8931dd3a33e94287e9a0bf5f7a 63 Pfam PF11127 Protein of unknown function (DUF2892) 4 62 2.7E-22 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 THSYN_RS08470 0dcf363dccc1711b80045140c95a1f60 191 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 5 188 4.3E-69 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 THSYN_RS08470 0dcf363dccc1711b80045140c95a1f60 191 Pfam PF02669 K+-transporting ATPase, c chain 6 187 3.8E-72 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 THSYN_RS08470 0dcf363dccc1711b80045140c95a1f60 191 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 2 189 36.178 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 THSYN_RS08470 0dcf363dccc1711b80045140c95a1f60 191 PIRSF PIRSF001296 1 191 2.1E-73 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 THSYN_RS03040 2833bd213316cce2fdf717089468ecea 86 Pfam PF00550 Phosphopantetheine attachment site 13 82 1.3E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain THSYN_RS03040 2833bd213316cce2fdf717089468ecea 86 Gene3D G3DSA:1.10.1200.10 4 85 6.3E-15 T 29-03-2018 THSYN_RS03040 2833bd213316cce2fdf717089468ecea 86 SUPERFAMILY SSF47336 4 83 1.83E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain THSYN_RS25170 df515db1450c5bf82b2b0a66966520c2 324 Pfam PF07507 WavE lipopolysaccharide synthesis 11 268 5.1E-37 T 29-03-2018 IPR011122 WavE lipopolysaccharide synthesis THSYN_RS26080 93d79ece4020cc74a5d6e3fc3f8dc05b 298 Hamap MF_00361 NAD kinase [nadK]. 5 288 32.702 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 THSYN_RS26080 93d79ece4020cc74a5d6e3fc3f8dc05b 298 Gene3D G3DSA:2.60.200.30 142 264 3.5E-37 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 THSYN_RS26080 93d79ece4020cc74a5d6e3fc3f8dc05b 298 SUPERFAMILY SSF111331 14 291 4.84E-81 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain THSYN_RS26080 93d79ece4020cc74a5d6e3fc3f8dc05b 298 Gene3D G3DSA:3.40.50.10330 1 141 2.9E-34 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 THSYN_RS26080 93d79ece4020cc74a5d6e3fc3f8dc05b 298 Pfam PF01513 ATP-NAD kinase 57 271 2.0E-57 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 THSYN_RS27440 b35dcef7378d0449c45dfdaac45a8beb 480 SMART SM00155 88 115 4.8E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 THSYN_RS27440 b35dcef7378d0449c45dfdaac45a8beb 480 Gene3D G3DSA:1.10.287.110 160 373 4.6E-7 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS27440 b35dcef7378d0449c45dfdaac45a8beb 480 SUPERFAMILY SSF56024 9 146 1.5E-21 T 29-03-2018 THSYN_RS27440 b35dcef7378d0449c45dfdaac45a8beb 480 Gene3D G3DSA:3.30.870.10 2 159 6.8E-22 T 29-03-2018 THSYN_RS27440 b35dcef7378d0449c45dfdaac45a8beb 480 Pfam PF13091 PLD-like domain 16 145 3.8E-18 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THSYN_RS27440 b35dcef7378d0449c45dfdaac45a8beb 480 SUPERFAMILY SSF46565 331 372 5.63E-7 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS03120 0d2b213457d423a5c15044cab0faf4f9 836 Gene3D G3DSA:3.40.50.200 262 646 3.7E-34 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS03120 0d2b213457d423a5c15044cab0faf4f9 836 SUPERFAMILY SSF52743 265 639 2.88E-44 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS03120 0d2b213457d423a5c15044cab0faf4f9 836 Pfam PF00082 Subtilase family 284 624 1.6E-39 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THSYN_RS03120 0d2b213457d423a5c15044cab0faf4f9 836 PRINTS PR00723 Subtilisin serine protease family (S8) signature 556 572 8.2E-6 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS03120 0d2b213457d423a5c15044cab0faf4f9 836 PRINTS PR00723 Subtilisin serine protease family (S8) signature 321 334 8.2E-6 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS03120 0d2b213457d423a5c15044cab0faf4f9 836 PRINTS PR00723 Subtilisin serine protease family (S8) signature 282 301 8.2E-6 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related THSYN_RS23850 e4b1620dd94cfc9ada21d928f92a36aa 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 29-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THSYN_RS23850 e4b1620dd94cfc9ada21d928f92a36aa 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.083 T 29-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid THSYN_RS23850 e4b1620dd94cfc9ada21d928f92a36aa 101 Gene3D G3DSA:4.10.830.10 1 101 1.2E-30 T 29-03-2018 THSYN_RS23850 e4b1620dd94cfc9ada21d928f92a36aa 101 SUPERFAMILY SSF57716 2 101 1.21E-33 T 29-03-2018 THSYN_RS23850 e4b1620dd94cfc9ada21d928f92a36aa 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 1.6E-24 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THSYN_RS14545 bb2f2b6d7bd43107727bd1cd4ddcbdc2 298 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 4 298 56.507 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 THSYN_RS14545 bb2f2b6d7bd43107727bd1cd4ddcbdc2 298 SUPERFAMILY SSF47823 4 100 4.71E-29 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal THSYN_RS14545 bb2f2b6d7bd43107727bd1cd4ddcbdc2 298 Gene3D G3DSA:1.10.443.10 112 292 2.5E-46 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS14545 bb2f2b6d7bd43107727bd1cd4ddcbdc2 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 91 4.2E-17 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THSYN_RS14545 bb2f2b6d7bd43107727bd1cd4ddcbdc2 298 Gene3D G3DSA:1.10.150.130 4 108 1.1E-20 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS14545 bb2f2b6d7bd43107727bd1cd4ddcbdc2 298 SUPERFAMILY SSF56349 108 296 2.94E-55 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS14545 bb2f2b6d7bd43107727bd1cd4ddcbdc2 298 Pfam PF00589 Phage integrase family 113 283 2.0E-47 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS14545 bb2f2b6d7bd43107727bd1cd4ddcbdc2 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 298 54.137 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD THSYN_RS14545 bb2f2b6d7bd43107727bd1cd4ddcbdc2 298 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 10 297 3.4E-110 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 THSYN_RS27240 08dc1e37536f3a7160ead7885134246f 697 SUPERFAMILY SSF53300 252 411 1.39E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS27240 08dc1e37536f3a7160ead7885134246f 697 Gene3D G3DSA:3.40.50.410 248 482 3.9E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS19470 4297c8f6b25d96c0031aac8f7601e234 221 Gene3D G3DSA:3.40.50.410 5 186 7.5E-24 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS19470 4297c8f6b25d96c0031aac8f7601e234 221 SUPERFAMILY SSF53300 20 174 7.57E-23 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS19470 4297c8f6b25d96c0031aac8f7601e234 221 Pfam PF00092 von Willebrand factor type A domain 22 169 1.1E-7 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS19470 4297c8f6b25d96c0031aac8f7601e234 221 PIRSF PIRSF020634 16 221 3.8E-74 T 29-03-2018 IPR011392 Tellurite resistance, TerY THSYN_RS19470 4297c8f6b25d96c0031aac8f7601e234 221 SMART SM00327 18 195 3.9E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS11390 f6710f03d7e4202223ad4087e1a3dd63 102 Gene3D G3DSA:3.30.460.10 3 100 6.9E-18 T 29-03-2018 THSYN_RS11390 f6710f03d7e4202223ad4087e1a3dd63 102 SUPERFAMILY SSF81301 6 97 1.94E-18 T 29-03-2018 THSYN_RS11390 f6710f03d7e4202223ad4087e1a3dd63 102 Pfam PF01909 Nucleotidyltransferase domain 16 95 1.3E-10 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS17025 b49a70e43ff86465b843bfcc97892a17 424 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 86 310 2.2E-38 T 29-03-2018 IPR000477 Reverse transcriptase domain THSYN_RS17025 b49a70e43ff86465b843bfcc97892a17 424 Gene3D G3DSA:3.30.70.270 107 310 8.1E-30 T 29-03-2018 THSYN_RS17025 b49a70e43ff86465b843bfcc97892a17 424 SUPERFAMILY SSF56672 36 369 1.59E-49 T 29-03-2018 THSYN_RS17025 b49a70e43ff86465b843bfcc97892a17 424 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 34 395 4.5E-101 T 29-03-2018 IPR030931 Group II intron reverse transcriptase/maturase THSYN_RS00270 4b4a2373b4f79012218aab2cc4bd83de 308 Pfam PF00892 EamA-like transporter family 15 148 1.1E-11 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 THSYN_RS00270 4b4a2373b4f79012218aab2cc4bd83de 308 Pfam PF00892 EamA-like transporter family 161 298 3.3E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 THSYN_RS00270 4b4a2373b4f79012218aab2cc4bd83de 308 SUPERFAMILY SSF103481 50 150 1.11E-11 T 29-03-2018 THSYN_RS00270 4b4a2373b4f79012218aab2cc4bd83de 308 SUPERFAMILY SSF103481 212 297 1.83E-9 T 29-03-2018 THSYN_RS04375 b875cc0e956e3d3ad46512b7075cc1ca 371 Gene3D G3DSA:3.40.50.2300 9 149 8.3E-24 T 29-03-2018 THSYN_RS04375 b875cc0e956e3d3ad46512b7075cc1ca 371 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 10 356 30.137 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS04375 b875cc0e956e3d3ad46512b7075cc1ca 371 PIRSF PIRSF000876 7 358 4.5E-97 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS04375 b875cc0e956e3d3ad46512b7075cc1ca 371 SUPERFAMILY SSF52172 9 112 6.97E-23 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS04375 b875cc0e956e3d3ad46512b7075cc1ca 371 Pfam PF00072 Response regulator receiver domain 12 112 2.7E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS04375 b875cc0e956e3d3ad46512b7075cc1ca 371 SMART SM00448 10 124 7.7E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS04375 b875cc0e956e3d3ad46512b7075cc1ca 371 Gene3D G3DSA:3.40.50.180 165 362 6.2E-65 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS04375 b875cc0e956e3d3ad46512b7075cc1ca 371 Pfam PF01339 CheB methylesterase 175 351 1.8E-52 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS04375 b875cc0e956e3d3ad46512b7075cc1ca 371 SUPERFAMILY SSF52738 173 355 7.59E-57 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THSYN_RS06185 49422ed123105db11c6d30af1fc16a60 107 Pfam PF04255 Protein of unknown function (DUF433) 9 64 1.2E-15 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS06185 49422ed123105db11c6d30af1fc16a60 107 Gene3D G3DSA:1.10.10.10 9 72 7.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS06185 49422ed123105db11c6d30af1fc16a60 107 SUPERFAMILY SSF46689 5 76 3.4E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS11990 b6277498a72daeff0903a7bdd95e67a1 84 SUPERFAMILY SSF143120 1 48 4.32E-11 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS11990 b6277498a72daeff0903a7bdd95e67a1 84 Gene3D G3DSA:3.40.1620.10 1 58 5.3E-11 T 29-03-2018 THSYN_RS11990 b6277498a72daeff0903a7bdd95e67a1 84 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 48 4.0E-6 T 29-03-2018 THSYN_RS11990 b6277498a72daeff0903a7bdd95e67a1 84 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 66 5.5E-11 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS13210 c64c61b9ffd881c8c3802064a23cce8a 111 Gene3D G3DSA:3.30.460.10 2 111 3.5E-19 T 29-03-2018 THSYN_RS13210 c64c61b9ffd881c8c3802064a23cce8a 111 SUPERFAMILY SSF81301 9 111 3.74E-21 T 29-03-2018 THSYN_RS13210 c64c61b9ffd881c8c3802064a23cce8a 111 Pfam PF01909 Nucleotidyltransferase domain 23 58 1.4E-7 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS30120 e565154bee01225ac3664c2ba0f7717d 247 Pfam PF14460 Prokaryotic E2 family D 62 233 5.5E-32 T 29-03-2018 IPR032787 Prokaryotic E2 family D THSYN_RS30120 e565154bee01225ac3664c2ba0f7717d 247 TIGRFAM TIGR03737 PRTRC_B: PRTRC system protein B 18 241 1.7E-48 T 29-03-2018 IPR022280 ParB-related, ThiF-related cassette, protein B THSYN_RS07290 0f4cc718bf5d81f1a911345255e98a20 163 Gene3D G3DSA:3.40.630.30 8 157 1.1E-22 T 29-03-2018 THSYN_RS07290 0f4cc718bf5d81f1a911345255e98a20 163 Pfam PF00583 Acetyltransferase (GNAT) family 47 133 7.3E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS07290 0f4cc718bf5d81f1a911345255e98a20 163 SUPERFAMILY SSF55729 30 157 4.36E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS07300 4d0919d327f66708d39917b1901b3507 193 Pfam PF13432 Tetratricopeptide repeat 83 142 1.8E-5 T 29-03-2018 THSYN_RS07300 4d0919d327f66708d39917b1901b3507 193 Pfam PF13432 Tetratricopeptide repeat 150 191 0.0085 T 29-03-2018 THSYN_RS07300 4d0919d327f66708d39917b1901b3507 193 SUPERFAMILY SSF48452 74 181 1.03E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS07300 4d0919d327f66708d39917b1901b3507 193 SMART SM00028 77 110 0.023 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS07300 4d0919d327f66708d39917b1901b3507 193 SMART SM00028 111 144 24.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS07300 4d0919d327f66708d39917b1901b3507 193 SMART SM00028 145 178 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS07300 4d0919d327f66708d39917b1901b3507 193 Gene3D G3DSA:1.25.40.10 130 188 3.3E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS07300 4d0919d327f66708d39917b1901b3507 193 Gene3D G3DSA:1.25.40.10 53 129 7.0E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS09400 4929cf3d60a56624503f381115993e82 502 SUPERFAMILY SSF52540 239 464 9.0E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09400 4929cf3d60a56624503f381115993e82 502 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 270 396 8.1E-19 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS09400 4929cf3d60a56624503f381115993e82 502 Gene3D G3DSA:3.40.50.300 94 403 7.1E-26 T 29-03-2018 THSYN_RS09400 4929cf3d60a56624503f381115993e82 502 Gene3D G3DSA:1.10.8.60 404 479 1.1E-5 T 29-03-2018 THSYN_RS09400 4929cf3d60a56624503f381115993e82 502 SMART SM00382 266 399 5.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS12515 4a9ab557fe0849eb7b5eb3585d50d315 273 Gene3D G3DSA:3.90.1580.10 20 272 1.5E-61 T 29-03-2018 THSYN_RS12515 4a9ab557fe0849eb7b5eb3585d50d315 273 Pfam PF03781 Sulfatase-modifying factor enzyme 1 33 265 1.6E-47 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS12515 4a9ab557fe0849eb7b5eb3585d50d315 273 SUPERFAMILY SSF56436 33 266 4.9E-62 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS02735 e3020671ddc1f0741a57e81a9d3e5d58 168 Pfam PF02464 Competence-damaged protein 7 158 9.9E-60 T 29-03-2018 IPR008136 CinA, C-terminal THSYN_RS02735 e3020671ddc1f0741a57e81a9d3e5d58 168 SUPERFAMILY SSF142433 4 160 5.23E-57 T 29-03-2018 IPR008136 CinA, C-terminal THSYN_RS02735 e3020671ddc1f0741a57e81a9d3e5d58 168 Gene3D G3DSA:3.90.950.20 1 164 6.9E-59 T 29-03-2018 THSYN_RS02735 e3020671ddc1f0741a57e81a9d3e5d58 168 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 13 158 5.4E-53 T 29-03-2018 IPR008136 CinA, C-terminal THSYN_RS31120 78346fc18b812593cfe1a86181c2c6c2 204 Pfam PF03006 Haemolysin-III related 5 197 1.1E-37 T 29-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 THSYN_RS31120 78346fc18b812593cfe1a86181c2c6c2 204 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 5 204 6.5E-61 T 29-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 THSYN_RS25765 1b4b1469e59cefbe5c58aeeda0db9128 317 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 12 301 1.3E-56 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THSYN_RS25765 1b4b1469e59cefbe5c58aeeda0db9128 317 PIRSF PIRSF026649 10 310 1.2E-84 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THSYN_RS29900 9b25302580807ad828614167066b9d5d 582 Pfam PF06114 IrrE N-terminal-like domain 421 557 1.1E-11 T 29-03-2018 IPR010359 IrrE N-terminal-like domain THSYN_RS24620 310d11c4e25a36215c61154731184a92 175 Gene3D G3DSA:3.40.30.10 93 175 4.9E-12 T 29-03-2018 THSYN_RS24620 310d11c4e25a36215c61154731184a92 175 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 132 150 - T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24620 310d11c4e25a36215c61154731184a92 175 SUPERFAMILY SSF52833 21 174 2.57E-47 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS24620 310d11c4e25a36215c61154731184a92 175 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 29 174 3.4E-48 T 29-03-2018 THSYN_RS24620 310d11c4e25a36215c61154731184a92 175 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 28 174 4.0E-53 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS24620 310d11c4e25a36215c61154731184a92 175 PIRSF PIRSF000216 10 175 7.3E-55 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS18375 4be30db957f537bed01c4fbc55982163 170 SUPERFAMILY SSF103247 39 160 1.7E-12 T 29-03-2018 IPR005180 Domain of unknown function DUF302 THSYN_RS18375 4be30db957f537bed01c4fbc55982163 170 Pfam PF03625 Domain of unknown function DUF302 70 131 2.2E-8 T 29-03-2018 IPR005180 Domain of unknown function DUF302 THSYN_RS18375 4be30db957f537bed01c4fbc55982163 170 Gene3D G3DSA:3.30.310.70 38 161 4.7E-14 T 29-03-2018 IPR005180 Domain of unknown function DUF302 THSYN_RS11295 bbbcd7fbd6d9fec861ab240ddaae2b6c 169 SUPERFAMILY SSF50475 6 150 4.68E-22 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 THSYN_RS11295 bbbcd7fbd6d9fec861ab240ddaae2b6c 169 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 88 1.2E-7 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THSYN_RS11295 bbbcd7fbd6d9fec861ab240ddaae2b6c 169 Gene3D G3DSA:2.30.110.10 4 160 5.3E-24 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 THSYN_RS21995 909447a9a9b1dae3a290697f1d955bcd 190 Pfam PF03938 Outer membrane protein (OmpH-like) 11 183 5.9E-29 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 THSYN_RS21995 909447a9a9b1dae3a290697f1d955bcd 190 SMART SM00935 31 184 1.3E-36 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 THSYN_RS21995 909447a9a9b1dae3a290697f1d955bcd 190 SUPERFAMILY SSF111384 43 184 3.79E-26 T 29-03-2018 IPR024930 Skp domain THSYN_RS21995 909447a9a9b1dae3a290697f1d955bcd 190 Gene3D G3DSA:3.30.910.20 31 184 3.2E-21 T 29-03-2018 THSYN_RS19655 583fe355ece3d9172986fe705b75c7cf 132 Gene3D G3DSA:3.10.129.10 1 132 6.3E-26 T 29-03-2018 THSYN_RS19655 583fe355ece3d9172986fe705b75c7cf 132 SUPERFAMILY SSF54637 6 124 5.66E-28 T 29-03-2018 IPR029069 HotDog domain THSYN_RS19655 583fe355ece3d9172986fe705b75c7cf 132 Pfam PF13279 Thioesterase-like superfamily 13 111 2.8E-11 T 29-03-2018 THSYN_RS07185 bd73a641c876568c50a007e5ed0a5bda 326 Gene3D G3DSA:3.90.1570.10 23 213 1.1E-20 T 29-03-2018 THSYN_RS07185 bd73a641c876568c50a007e5ed0a5bda 326 Pfam PF05685 Putative restriction endonuclease 36 206 9.9E-15 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS07185 bd73a641c876568c50a007e5ed0a5bda 326 SUPERFAMILY SSF52980 24 210 4.72E-19 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS03090 4535df56ece4c5a0175b21657a6f9295 396 Pfam PF01609 Transposase DDE domain 91 329 1.7E-15 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS03090 4535df56ece4c5a0175b21657a6f9295 396 SUPERFAMILY SSF53098 12 364 1.74E-38 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS03090 4535df56ece4c5a0175b21657a6f9295 396 Gene3D G3DSA:3.90.350.10 136 309 2.3E-16 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS27555 345d700d34de6bd37089835c04ce5fb2 207 Gene3D G3DSA:1.20.950.20 2 207 1.7E-48 T 29-03-2018 THSYN_RS27555 345d700d34de6bd37089835c04ce5fb2 207 SUPERFAMILY SSF81342 5 206 6.02E-48 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THSYN_RS27555 345d700d34de6bd37089835c04ce5fb2 207 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 8 205 1.0E-52 T 29-03-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 THSYN_RS27555 345d700d34de6bd37089835c04ce5fb2 207 Pfam PF01292 Prokaryotic cytochrome b561 10 185 5.0E-24 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THSYN_RS06550 0ea5f6a89692daad25ed7ca89dd83225 396 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 57 277 1.6E-18 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 THSYN_RS06550 0ea5f6a89692daad25ed7ca89dd83225 396 SUPERFAMILY SSF53649 53 394 1.7E-42 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS06550 0ea5f6a89692daad25ed7ca89dd83225 396 Gene3D G3DSA:3.40.720.10 36 394 1.4E-21 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS20565 5b020c38069d97ced879146574ff44e1 290 Gene3D G3DSA:1.10.510.10 7 237 3.7E-13 T 29-03-2018 THSYN_RS20565 5b020c38069d97ced879146574ff44e1 290 SUPERFAMILY SSF56112 11 221 5.76E-15 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS11790 f46a2a34ca3496e4fc53f4ae70cf4d5d 234 Gene3D G3DSA:2.40.440.10 98 217 1.4E-24 T 29-03-2018 THSYN_RS11790 f46a2a34ca3496e4fc53f4ae70cf4d5d 234 Pfam PF03734 L,D-transpeptidase catalytic domain 107 215 8.2E-18 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 THSYN_RS11790 f46a2a34ca3496e4fc53f4ae70cf4d5d 234 SUPERFAMILY SSF141523 103 215 3.53E-24 T 29-03-2018 THSYN_RS00360 28bcd471b34bcfd583490d229800e542 440 Pfam PF00909 Ammonium Transporter Family 40 438 1.7E-122 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 THSYN_RS00360 28bcd471b34bcfd583490d229800e542 440 Gene3D G3DSA:1.10.3430.10 30 419 8.1E-134 T 29-03-2018 THSYN_RS00360 28bcd471b34bcfd583490d229800e542 440 TIGRFAM TIGR00836 amt: ammonium transporter 38 438 8.7E-140 T 29-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 THSYN_RS00360 28bcd471b34bcfd583490d229800e542 440 SUPERFAMILY SSF111352 34 419 1.44E-131 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 THSYN_RS00360 28bcd471b34bcfd583490d229800e542 440 ProSitePatterns PS01219 Ammonium transporters signature. 194 219 - T 29-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 THSYN_RS15450 144669f9ab36cc30c26ec57e55356348 171 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 25 167 3.0E-28 T 29-03-2018 IPR011747 Conserved hypothetical protein CHP02241 THSYN_RS15450 144669f9ab36cc30c26ec57e55356348 171 Pfam PF06841 T4-like virus tail tube protein gp19 11 166 1.5E-31 T 29-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 THSYN_RS23505 ce071c2a145dc4ccb08a2b86bfc17180 373 Pfam PF10442 FIST C domain 220 358 9.4E-27 T 29-03-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 THSYN_RS23505 ce071c2a145dc4ccb08a2b86bfc17180 373 SMART SM01204 220 360 9.7E-34 T 29-03-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 THSYN_RS23505 ce071c2a145dc4ccb08a2b86bfc17180 373 Pfam PF08495 FIST N domain 34 218 2.8E-28 T 29-03-2018 IPR013702 FIST domain, N-terminal THSYN_RS23505 ce071c2a145dc4ccb08a2b86bfc17180 373 SMART SM00897 31 219 1.9E-32 T 29-03-2018 IPR013702 FIST domain, N-terminal THSYN_RS23505 ce071c2a145dc4ccb08a2b86bfc17180 373 PIRSF PIRSF018953 9 373 8.6E-56 T 29-03-2018 IPR016741 Uncharacterised conserved protein UCP018953 THSYN_RS19310 6506584e21236aea123ed047bf050fbd 228 Pfam PF01292 Prokaryotic cytochrome b561 9 178 8.6E-21 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THSYN_RS19310 6506584e21236aea123ed047bf050fbd 228 SUPERFAMILY SSF81342 4 182 3.37E-32 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THSYN_RS19310 6506584e21236aea123ed047bf050fbd 228 Gene3D G3DSA:1.20.950.20 1 188 5.1E-30 T 29-03-2018 THSYN_RS27815 7d1168128e9e843912de146a27bb359e 251 Pfam PF01925 Sulfite exporter TauE/SafE 10 245 7.2E-46 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 SMART SM00028 120 156 420.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 SMART SM00028 264 300 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 SMART SM00028 360 396 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 SMART SM00028 168 204 220.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 SMART SM00028 312 348 130.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 SMART SM00028 461 494 55.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 SMART SM00028 408 444 220.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 SUPERFAMILY SSF48452 210 374 2.66E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 SUPERFAMILY SSF48452 67 230 8.09E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 Gene3D G3DSA:1.25.40.10 593 1036 7.7E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 Gene3D G3DSA:1.10.150.200 123 199 0.011 T 29-03-2018 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 Gene3D G3DSA:1.10.150.200 205 272 0.036 T 29-03-2018 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 Gene3D G3DSA:1.10.150.200 50 122 0.002 T 29-03-2018 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 Gene3D G3DSA:1.25.40.10 273 315 2.2E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 Gene3D G3DSA:1.25.40.10 316 365 4.7E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 Gene3D G3DSA:1.25.40.10 404 484 2.7E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS14295 88e02b106fd0f20e859f52808744b279 1078 Gene3D G3DSA:1.25.40.10 366 397 0.13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS05195 7e351fc802afd8f753d62bac913e93a5 1253 Pfam PF13809 Tubulin like 23 394 2.5E-52 T 29-03-2018 IPR025904 Tubulin-like THSYN_RS05195 7e351fc802afd8f753d62bac913e93a5 1253 Gene3D G3DSA:3.40.50.1440 21 343 1.4E-18 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THSYN_RS05195 7e351fc802afd8f753d62bac913e93a5 1253 Pfam PF14237 Domain of unknown function (DUF4339) 1169 1211 7.0E-13 T 29-03-2018 IPR025640 Domain of unknown function DUF4339 Reactome: R-HSA-6798695 THSYN_RS29680 d8b249ee2b1b79a3beb92947146f10c7 104 Gene3D G3DSA:3.30.2310.20 4 95 4.9E-6 T 29-03-2018 THSYN_RS29680 d8b249ee2b1b79a3beb92947146f10c7 104 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 7 93 3.9E-18 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS08275 c86254a9b3e9197f18f9654c749b7843 277 Pfam PF13444 Acetyltransferase (GNAT) domain 39 135 5.1E-18 T 29-03-2018 THSYN_RS08275 c86254a9b3e9197f18f9654c749b7843 277 Gene3D G3DSA:3.40.630.30 23 242 2.3E-29 T 29-03-2018 THSYN_RS08275 c86254a9b3e9197f18f9654c749b7843 277 TIGRFAM TIGR03694 exosort_acyl: N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated 22 231 2.9E-36 T 29-03-2018 IPR022484 PEP-CTERM/exosortase system-associated acyltransferase, predicted THSYN_RS08275 c86254a9b3e9197f18f9654c749b7843 277 SUPERFAMILY SSF55729 22 131 5.72E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS08275 c86254a9b3e9197f18f9654c749b7843 277 SUPERFAMILY SSF55729 161 215 5.72E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS01170 53fc9927341db4141e0d6c5543da0002 245 Gene3D G3DSA:1.20.58.130 7 195 8.3E-6 T 29-03-2018 THSYN_RS01170 53fc9927341db4141e0d6c5543da0002 245 SUPERFAMILY SSF52980 47 233 2.47E-8 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS17575 b3101057dd18da39d2c8f28086730dfb 93 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 5 83 2.1E-26 T 29-03-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THSYN_RS24455 fc9bbe44488301b91e071d879244e8a6 187 Gene3D G3DSA:3.40.50.850 3 187 1.1E-37 T 29-03-2018 THSYN_RS24455 fc9bbe44488301b91e071d879244e8a6 187 Pfam PF00857 Isochorismatase family 10 162 1.8E-26 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THSYN_RS24455 fc9bbe44488301b91e071d879244e8a6 187 SUPERFAMILY SSF52499 5 185 9.94E-45 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THSYN_RS14170 7dfa30c6c9c76d169e90adf87afdd7db 96 Gene3D G3DSA:1.20.5.1230 8 95 3.6E-4 T 29-03-2018 THSYN_RS24520 8518af53af04316d6d10a84fa4951e74 508 SUPERFAMILY SSF117457 318 488 1.44E-58 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THSYN_RS24520 8518af53af04316d6d10a84fa4951e74 508 Gene3D G3DSA:3.20.130.10 314 489 5.5E-61 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THSYN_RS24520 8518af53af04316d6d10a84fa4951e74 508 Pfam PF05681 Fumarate hydratase (Fumerase) 11 284 1.9E-98 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 THSYN_RS24520 8518af53af04316d6d10a84fa4951e74 508 Pfam PF05683 Fumarase C-terminus 288 490 1.4E-78 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THSYN_RS24520 8518af53af04316d6d10a84fa4951e74 508 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 284 4.0E-64 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 THSYN_RS24520 8518af53af04316d6d10a84fa4951e74 508 PIRSF PIRSF001394 1 507 3.6E-206 T 29-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 THSYN_RS24520 8518af53af04316d6d10a84fa4951e74 508 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 325 489 3.0E-43 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THSYN_RS31180 fdc8de484a472a5fc5d598632b3055b3 107 Gene3D G3DSA:1.10.1220.10 2 40 0.0045 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS27245 69c5541f1de277a26c81cd5f7e7dc41d 400 Gene3D G3DSA:3.40.710.10 19 399 9.2E-59 T 29-03-2018 THSYN_RS27245 69c5541f1de277a26c81cd5f7e7dc41d 400 SUPERFAMILY SSF56601 33 381 1.19E-60 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS27245 69c5541f1de277a26c81cd5f7e7dc41d 400 Pfam PF00144 Beta-lactamase 68 385 8.7E-50 T 29-03-2018 IPR001466 Beta-lactamase-related THSYN_RS25590 e73f973367785bf4924fc0597b3cd7ec 518 Pfam PF09820 Predicted AAA-ATPase 7 271 6.9E-90 T 29-03-2018 IPR018631 AAA-ATPase-like domain THSYN_RS25590 e73f973367785bf4924fc0597b3cd7ec 518 Pfam PF08011 PD-(D/E)XK nuclease superfamily 417 508 1.6E-21 T 29-03-2018 IPR012547 PD-(D/E)XK nuclease superfamily 9 THSYN_RS00085 3eae5d3c023eb06425b875f2fbb0d7fc 167 Pfam PF01420 Type I restriction modification DNA specificity domain 14 128 1.7E-7 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS00085 3eae5d3c023eb06425b875f2fbb0d7fc 167 SUPERFAMILY SSF116734 6 160 2.45E-28 T 29-03-2018 THSYN_RS00085 3eae5d3c023eb06425b875f2fbb0d7fc 167 Gene3D G3DSA:3.90.220.20 2 132 6.5E-19 T 29-03-2018 THSYN_RS17585 04f805ca58d8bafcf754b118435f7c69 122 SMART SM00530 19 74 1.2E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS17585 04f805ca58d8bafcf754b118435f7c69 122 Gene3D G3DSA:1.10.260.40 5 81 3.9E-15 T 29-03-2018 THSYN_RS17585 04f805ca58d8bafcf754b118435f7c69 122 SUPERFAMILY SSF47413 9 71 2.2E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS17585 04f805ca58d8bafcf754b118435f7c69 122 Pfam PF13560 Helix-turn-helix domain 15 72 1.4E-9 T 29-03-2018 THSYN_RS28555 9ab9244d5da77c73e53427e6f41a6c3f 618 Gene3D G3DSA:1.20.1640.10 407 610 1.3E-31 T 29-03-2018 THSYN_RS28555 9ab9244d5da77c73e53427e6f41a6c3f 618 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 123 604 2.5E-143 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 THSYN_RS28555 9ab9244d5da77c73e53427e6f41a6c3f 618 SUPERFAMILY SSF82866 414 611 1.31E-42 T 29-03-2018 THSYN_RS28555 9ab9244d5da77c73e53427e6f41a6c3f 618 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 617 49.126 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 THSYN_RS28555 9ab9244d5da77c73e53427e6f41a6c3f 618 Pfam PF13721 SecD export protein N-terminal TM region 1 103 4.0E-27 T 29-03-2018 IPR027398 SecD export protein N-terminal TM domain THSYN_RS28555 9ab9244d5da77c73e53427e6f41a6c3f 618 Pfam PF02355 Protein export membrane protein 437 606 8.7E-20 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial THSYN_RS28555 9ab9244d5da77c73e53427e6f41a6c3f 618 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 348 597 3.9E-79 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THSYN_RS28555 9ab9244d5da77c73e53427e6f41a6c3f 618 Pfam PF07549 SecD/SecF GG Motif 116 141 5.8E-6 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site THSYN_RS22415 91c51d62a11f32db190eb3fb223f70ba 157 SUPERFAMILY SSF52540 6 76 1.99E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22415 91c51d62a11f32db190eb3fb223f70ba 157 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 6 57 2.5E-11 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS22415 91c51d62a11f32db190eb3fb223f70ba 157 Gene3D G3DSA:3.40.50.300 1 126 5.0E-12 T 29-03-2018 THSYN_RS19705 9d19488d6bfa431ab6e867d6cfe9072e 449 TIGRFAM TIGR02794 tolA_full: protein TolA 203 449 3.8E-28 T 29-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 THSYN_RS19705 9d19488d6bfa431ab6e867d6cfe9072e 449 TIGRFAM TIGR02794 tolA_full: protein TolA 9 241 1.1E-17 T 29-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 THSYN_RS19705 9d19488d6bfa431ab6e867d6cfe9072e 449 Pfam PF13103 TonB C terminal 361 445 2.1E-17 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 THSYN_RS19705 9d19488d6bfa431ab6e867d6cfe9072e 449 Gene3D G3DSA:3.30.1150.10 348 449 2.7E-19 T 29-03-2018 THSYN_RS19705 9d19488d6bfa431ab6e867d6cfe9072e 449 SUPERFAMILY SSF74653 358 449 7.59E-14 T 29-03-2018 THSYN_RS22930 cddb9f584724c5d0722a918d35fd39ce 118 Pfam PF09722 Protein of unknown function (DUF2384) 69 116 3.3E-10 T 29-03-2018 IPR024467 Domain of unknown function DUF2384 THSYN_RS11540 9e61aea598b502ef39ef402782a333f3 143 Pfam PF05717 IS66 Orf2 like protein 9 105 1.6E-29 T 29-03-2018 IPR008878 Transposase IS66, Orf2 THSYN_RS11005 f4d665a9b047456d02b6befb3ca09a4c 245 Gene3D G3DSA:1.10.3720.10 18 237 2.5E-42 T 29-03-2018 THSYN_RS11005 f4d665a9b047456d02b6befb3ca09a4c 245 SUPERFAMILY SSF161098 24 222 2.49E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS11005 f4d665a9b047456d02b6befb3ca09a4c 245 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 131 6.7E-20 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THSYN_RS11005 f4d665a9b047456d02b6befb3ca09a4c 245 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 237 1.9E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS25290 7149ef95b73e2a0c66a9b7f57dd1554d 239 Pfam PF12644 Protein of unknown function (DUF3782) 77 158 1.9E-24 T 29-03-2018 IPR024271 Protein of unknown function DUF3782 THSYN_RS25290 7149ef95b73e2a0c66a9b7f57dd1554d 239 Pfam PF07788 PD-(D/E)XK nuclease superfamily 159 228 6.6E-24 T 29-03-2018 IPR012431 PD-(D/E)XK nuclease THSYN_RS02990 14c20249167e4faf2831240830936ae3 257 Gene3D G3DSA:3.90.550.10 2 251 1.4E-20 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS02990 14c20249167e4faf2831240830936ae3 257 Pfam PF00535 Glycosyl transferase family 2 12 137 1.4E-15 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS02990 14c20249167e4faf2831240830936ae3 257 SUPERFAMILY SSF53448 12 245 1.31E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS29595 307412b40d2b528166e3e834934b1f68 99 Gene3D G3DSA:1.20.5.780 14 93 3.8E-27 T 29-03-2018 THSYN_RS29595 307412b40d2b528166e3e834934b1f68 99 SUPERFAMILY SSF47598 14 91 2.22E-21 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS29595 307412b40d2b528166e3e834934b1f68 99 Pfam PF08681 Protein of unknown function (DUF1778) 18 92 1.6E-24 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 THSYN_RS32035 ceb2ca6250fefb77deeab6f4d7324600 316 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 29 299 6.5E-46 T 29-03-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 THSYN_RS32035 ceb2ca6250fefb77deeab6f4d7324600 316 Gene3D G3DSA:3.40.50.20 15 117 1.7E-20 T 29-03-2018 THSYN_RS32035 ceb2ca6250fefb77deeab6f4d7324600 316 SUPERFAMILY SSF56059 121 304 2.65E-39 T 29-03-2018 THSYN_RS32035 ceb2ca6250fefb77deeab6f4d7324600 316 Gene3D G3DSA:3.30.470.20 196 293 4.0E-28 T 29-03-2018 THSYN_RS32035 ceb2ca6250fefb77deeab6f4d7324600 316 Pfam PF08443 RimK-like ATP-grasp domain 114 300 4.5E-21 T 29-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 THSYN_RS32035 ceb2ca6250fefb77deeab6f4d7324600 316 Gene3D G3DSA:3.30.1490.20 118 195 9.1E-9 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THSYN_RS04975 591a462800bb9feab9b52e0cfda9e89f 288 Gene3D G3DSA:3.50.50.60 28 273 5.3E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS04975 591a462800bb9feab9b52e0cfda9e89f 288 Pfam PF08861 Domain of unknown function DUF1828 68 144 2.7E-6 T 29-03-2018 IPR014960 Domain of unknown function DUF1828 THSYN_RS12990 49aff3947c1050918e00503d3027f2f0 210 Pfam PF00571 CBS domain 152 203 3.2E-8 T 29-03-2018 IPR000644 CBS domain THSYN_RS12990 49aff3947c1050918e00503d3027f2f0 210 Pfam PF00571 CBS domain 69 122 2.1E-9 T 29-03-2018 IPR000644 CBS domain THSYN_RS12990 49aff3947c1050918e00503d3027f2f0 210 SMART SM00116 157 205 0.0025 T 29-03-2018 IPR000644 CBS domain THSYN_RS12990 49aff3947c1050918e00503d3027f2f0 210 SMART SM00116 75 123 1.7E-6 T 29-03-2018 IPR000644 CBS domain THSYN_RS12990 49aff3947c1050918e00503d3027f2f0 210 SUPERFAMILY SSF54631 49 205 1.77E-24 T 29-03-2018 THSYN_RS12990 49aff3947c1050918e00503d3027f2f0 210 Gene3D G3DSA:3.10.580.10 142 210 8.3E-10 T 29-03-2018 THSYN_RS12990 49aff3947c1050918e00503d3027f2f0 210 Gene3D G3DSA:3.10.580.10 22 126 9.7E-13 T 29-03-2018 THSYN_RS11490 aaecd8153b54871e8f3c6669e3791927 1204 Gene3D G3DSA:3.40.50.300 148 403 4.7E-5 T 29-03-2018 THSYN_RS11490 aaecd8153b54871e8f3c6669e3791927 1204 SUPERFAMILY SSF52540 134 293 3.15E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS11490 aaecd8153b54871e8f3c6669e3791927 1204 Pfam PF06744 Type VI secretion protein IcmF C-terminal 957 1152 1.2E-60 T 29-03-2018 IPR010623 Type VI secretion system IcmF, C-terminal THSYN_RS11490 aaecd8153b54871e8f3c6669e3791927 1204 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 14 1202 0.0 T 29-03-2018 IPR017731 Type VI secretion system, IcmF THSYN_RS11490 aaecd8153b54871e8f3c6669e3791927 1204 Gene3D G3DSA:3.40.50.300 71 147 0.0093 T 29-03-2018 THSYN_RS11490 aaecd8153b54871e8f3c6669e3791927 1204 Pfam PF14331 ImcF-related N-terminal domain 199 457 2.5E-89 T 29-03-2018 IPR025743 ImcF-related, N-terminal domain THSYN_RS11490 aaecd8153b54871e8f3c6669e3791927 1204 Pfam PF06761 Intracellular multiplication and human macrophage-killing 512 818 5.1E-78 T 29-03-2018 IPR009612 ImcF-related THSYN_RS31500 ef090a6584ad819cd1cfdb60bef2a2c6 180 Gene3D G3DSA:2.160.10.10 9 176 1.4E-37 T 29-03-2018 THSYN_RS31500 ef090a6584ad819cd1cfdb60bef2a2c6 180 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 90 124 3.2E-8 T 29-03-2018 IPR001451 Hexapeptide repeat THSYN_RS31500 ef090a6584ad819cd1cfdb60bef2a2c6 180 SUPERFAMILY SSF51161 15 170 3.33E-43 T 29-03-2018 IPR011004 Trimeric LpxA-like THSYN_RS11835 179b4ab2d7079ad1c00a92200b120fb7 186 SUPERFAMILY SSF143422 1 142 2.75E-32 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS11835 179b4ab2d7079ad1c00a92200b120fb7 186 Pfam PF01797 Transposase IS200 like 22 134 5.7E-7 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS11835 179b4ab2d7079ad1c00a92200b120fb7 186 Gene3D G3DSA:3.30.70.1290 1 144 4.2E-33 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS11835 179b4ab2d7079ad1c00a92200b120fb7 186 SMART SM01321 9 136 6.0E-33 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS20130 4e7b36b55d35cba088a835fd95d5fa5e 485 Pfam PF02321 Outer membrane efflux protein 288 454 2.5E-22 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THSYN_RS20130 4e7b36b55d35cba088a835fd95d5fa5e 485 Pfam PF02321 Outer membrane efflux protein 73 264 3.5E-26 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THSYN_RS20130 4e7b36b55d35cba088a835fd95d5fa5e 485 SUPERFAMILY SSF56954 7 476 9.94E-110 T 29-03-2018 THSYN_RS20130 4e7b36b55d35cba088a835fd95d5fa5e 485 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 18 473 3.2E-134 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 THSYN_RS20130 4e7b36b55d35cba088a835fd95d5fa5e 485 Gene3D G3DSA:1.20.1600.10 25 479 3.4E-109 T 29-03-2018 THSYN_RS18355 34d2b4a9572f1502d87096ae103eaca3 125 Gene3D G3DSA:1.20.1560.10 1 94 9.9E-4 T 29-03-2018 THSYN_RS18355 34d2b4a9572f1502d87096ae103eaca3 125 Pfam PF13396 Phospholipase_D-nuclease N-terminal 19 64 1.8E-6 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal THSYN_RS31310 9f727b0bbbe4843a7c72a824ca43024e 393 SUPERFAMILY SSF51905 8 169 9.73E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31310 9f727b0bbbe4843a7c72a824ca43024e 393 SUPERFAMILY SSF51905 258 332 9.73E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31310 9f727b0bbbe4843a7c72a824ca43024e 393 Gene3D G3DSA:3.50.50.60 1 309 2.7E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS31310 9f727b0bbbe4843a7c72a824ca43024e 393 Pfam PF05834 Lycopene cyclase protein 12 370 1.9E-66 T 29-03-2018 THSYN_RS31310 9f727b0bbbe4843a7c72a824ca43024e 393 TIGRFAM TIGR01789 lycopene_cycl: lycopene cyclase 12 374 3.7E-75 T 29-03-2018 IPR008461 Lycopene cyclase GO:0016117|GO:0045436 THSYN_RS31310 9f727b0bbbe4843a7c72a824ca43024e 393 TIGRFAM TIGR01790 carotene-cycl: lycopene cyclase family protein 12 370 7.2E-66 T 29-03-2018 IPR010108 Lycopene cyclase, beta/epsilon GO:0016117|GO:0016705 THSYN_RS08925 0ce08ff7ec9e15b87bd611604d977992 133 Gene3D G3DSA:2.102.10.10 10 131 2.7E-14 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THSYN_RS08925 0ce08ff7ec9e15b87bd611604d977992 133 SUPERFAMILY SSF50022 14 124 5.5E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THSYN_RS08925 0ce08ff7ec9e15b87bd611604d977992 133 Pfam PF00355 Rieske [2Fe-2S] domain 45 102 2.2E-4 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THSYN_RS19820 be3788bb5b9652f4e82739dff3240007 280 SUPERFAMILY SSF52980 7 167 2.68E-29 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS19820 be3788bb5b9652f4e82739dff3240007 280 Gene3D G3DSA:3.90.1570.10 21 159 3.5E-22 T 29-03-2018 THSYN_RS19820 be3788bb5b9652f4e82739dff3240007 280 Pfam PF05685 Putative restriction endonuclease 45 158 4.0E-19 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS25865 94fa996311cf94ac5852328e41321669 336 Gene3D G3DSA:3.40.190.10 34 136 1.1E-11 T 29-03-2018 THSYN_RS25865 94fa996311cf94ac5852328e41321669 336 Pfam PF09084 NMT1/THI5 like 50 252 4.2E-28 T 29-03-2018 IPR015168 SsuA/THI5-like THSYN_RS25865 94fa996311cf94ac5852328e41321669 336 Gene3D G3DSA:3.40.190.10 137 326 4.4E-31 T 29-03-2018 THSYN_RS25865 94fa996311cf94ac5852328e41321669 336 SUPERFAMILY SSF53850 34 267 2.79E-42 T 29-03-2018 THSYN_RS06235 e4c73d635b9b4e09187ed0023db7a937 533 Gene3D G3DSA:3.30.420.40 190 364 9.0E-14 T 29-03-2018 THSYN_RS06235 e4c73d635b9b4e09187ed0023db7a937 533 Pfam PF00012 Hsp70 protein 3 518 7.1E-9 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THSYN_RS06235 e4c73d635b9b4e09187ed0023db7a937 533 Gene3D G3DSA:3.30.420.40 2 189 6.2E-29 T 29-03-2018 THSYN_RS06235 e4c73d635b9b4e09187ed0023db7a937 533 SUPERFAMILY SSF53067 3 169 5.5E-22 T 29-03-2018 THSYN_RS06235 e4c73d635b9b4e09187ed0023db7a937 533 SUPERFAMILY SSF53067 181 393 1.2E-13 T 29-03-2018 THSYN_RS08250 1666afa9e0eb8e612cb85717e357a984 390 SUPERFAMILY SSF51735 166 355 6.98E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS08250 1666afa9e0eb8e612cb85717e357a984 390 SUPERFAMILY SSF51735 1 129 6.98E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS08250 1666afa9e0eb8e612cb85717e357a984 390 Gene3D G3DSA:3.40.50.720 1 212 2.2E-38 T 29-03-2018 THSYN_RS08250 1666afa9e0eb8e612cb85717e357a984 390 Gene3D G3DSA:3.90.25.10 213 362 5.7E-38 T 29-03-2018 THSYN_RS08250 1666afa9e0eb8e612cb85717e357a984 390 PRINTS PR01713 Nucleotide sugar epimerase signature 275 290 4.3E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 THSYN_RS08250 1666afa9e0eb8e612cb85717e357a984 390 PRINTS PR01713 Nucleotide sugar epimerase signature 315 332 4.3E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 THSYN_RS08250 1666afa9e0eb8e612cb85717e357a984 390 PRINTS PR01713 Nucleotide sugar epimerase signature 252 267 4.3E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 THSYN_RS08250 1666afa9e0eb8e612cb85717e357a984 390 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 281 5.1E-46 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THSYN_RS20340 0da26ece0cadba8a389e5929864684c0 197 SUPERFAMILY SSF69118 37 107 4.32E-6 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 THSYN_RS15420 3d39148ab12bcaec9b81c9eabca418ed 319 Pfam PF14261 Domain of unknown function (DUF4351) 259 312 4.2E-9 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS01130 053da9e00b144b4cfad9d2e99ef58ddd 752 Gene3D G3DSA:3.40.50.1460 528 750 2.3E-18 T 29-03-2018 THSYN_RS01130 053da9e00b144b4cfad9d2e99ef58ddd 752 Pfam PF12770 CHAT domain 534 742 1.2E-12 T 29-03-2018 IPR024983 CHAT domain THSYN_RS26690 b093ac6ca2867e2664fd4178c8f8a3bf 329 Pfam PF07589 PEP-CTERM motif 302 323 8.1E-8 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS26690 b093ac6ca2867e2664fd4178c8f8a3bf 329 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 303 323 2.4E-5 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS33230 51c15f97a3faa3964a441a7d44e5bd9e 155 Gene3D G3DSA:3.10.420.10 2 155 4.8E-20 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS33230 51c15f97a3faa3964a441a7d44e5bd9e 155 SUPERFAMILY SSF54611 59 152 6.98E-12 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS33230 51c15f97a3faa3964a441a7d44e5bd9e 155 Pfam PF02556 Preprotein translocase subunit SecB 58 143 2.2E-7 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THSYN_RS31210 68d344dc711a67236010410f3eaea92c 189 Pfam PF00313 'Cold-shock' DNA-binding domain 5 66 2.6E-12 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THSYN_RS31210 68d344dc711a67236010410f3eaea92c 189 SMART SM00357 4 68 6.9E-9 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 THSYN_RS31210 68d344dc711a67236010410f3eaea92c 189 Pfam PF05901 Excalibur calcium-binding domain 148 181 3.1E-9 T 29-03-2018 IPR008613 Excalibur calcium-binding domain THSYN_RS31210 68d344dc711a67236010410f3eaea92c 189 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 35 - T 29-03-2018 IPR019844 Cold-shock conserved site THSYN_RS31210 68d344dc711a67236010410f3eaea92c 189 SUPERFAMILY SSF50249 1 68 1.71E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS31210 68d344dc711a67236010410f3eaea92c 189 Gene3D G3DSA:2.40.50.140 1 75 6.5E-18 T 29-03-2018 THSYN_RS07190 d2f3ed418e90a7a75a863ac8706e2915 291 Pfam PF14261 Domain of unknown function (DUF4351) 230 288 1.9E-19 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS07190 d2f3ed418e90a7a75a863ac8706e2915 291 Pfam PF11103 Protein of unknown function (DUF2887) 3 205 7.3E-27 T 29-03-2018 IPR022573 Protein of unknown function DUF2887 THSYN_RS14955 be5cefdbd1d62d68c2e03c38738fb514 292 SUPERFAMILY SSF52540 33 230 1.57E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14955 be5cefdbd1d62d68c2e03c38738fb514 292 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS14955 be5cefdbd1d62d68c2e03c38738fb514 292 Gene3D G3DSA:3.40.50.300 23 266 2.2E-44 T 29-03-2018 THSYN_RS14955 be5cefdbd1d62d68c2e03c38738fb514 292 SMART SM00382 44 235 1.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS14955 be5cefdbd1d62d68c2e03c38738fb514 292 Pfam PF00005 ABC transporter 40 185 4.4E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS32460 53504a102f84a97d0257ae9cf01202fa 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 138 151 3.9E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS32460 53504a102f84a97d0257ae9cf01202fa 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 80 95 3.9E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS32460 53504a102f84a97d0257ae9cf01202fa 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 124 137 3.9E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS32460 53504a102f84a97d0257ae9cf01202fa 308 SUPERFAMILY SSF53474 33 305 1.14E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS32460 53504a102f84a97d0257ae9cf01202fa 308 Gene3D G3DSA:3.40.50.1820 26 301 3.2E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS32460 53504a102f84a97d0257ae9cf01202fa 308 Pfam PF12697 Alpha/beta hydrolase family 55 274 3.4E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS14530 d8cf64465198e6560e04e0f2e26134ae 359 SUPERFAMILY SSF56300 122 343 6.47E-31 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS14530 d8cf64465198e6560e04e0f2e26134ae 359 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 126 284 1.4E-10 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 THSYN_RS14530 d8cf64465198e6560e04e0f2e26134ae 359 Gene3D G3DSA:3.60.21.10 122 330 1.1E-21 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS26740 ef85cc1ec969cb7b440c8445094bb5e0 154 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 6 136 5.7E-23 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 THSYN_RS26740 ef85cc1ec969cb7b440c8445094bb5e0 154 Gene3D G3DSA:1.20.120.50 1 141 2.3E-26 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 THSYN_RS26740 ef85cc1ec969cb7b440c8445094bb5e0 154 Pfam PF01814 Hemerythrin HHE cation binding domain 14 133 1.3E-11 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THSYN_RS26740 ef85cc1ec969cb7b440c8445094bb5e0 154 SUPERFAMILY SSF47188 3 136 1.83E-22 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 THSYN_RS13745 9aa3eccc2bf2dc26c15f6d9946594ed3 106 Pfam PF08895 Domain of unknown function (DUF1840) 1 103 4.5E-31 T 29-03-2018 IPR014991 Protein of unknown function DUF1840 THSYN_RS02925 d5047803a25323d3fb5ea6b0c33b00db 414 Pfam PF01061 ABC-2 type transporter 205 379 1.7E-22 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 THSYN_RS30105 c7961407ecefd7feb806cfaee14a4525 591 Pfam PF00773 RNB domain 110 439 1.1E-48 T 29-03-2018 THSYN_RS30105 c7961407ecefd7feb806cfaee14a4525 591 SUPERFAMILY SSF50249 75 461 1.94E-66 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS30105 c7961407ecefd7feb806cfaee14a4525 591 SMART SM00955 108 450 5.2E-51 T 29-03-2018 THSYN_RS21660 138bb9626062da553c8ff9e17d27a246 133 Gene3D G3DSA:2.60.120.260 20 133 4.0E-7 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS10555 49ac3e5d2a267805d6bd01c7175d8e98 90 Gene3D G3DSA:3.40.50.2300 22 89 7.9E-16 T 29-03-2018 THSYN_RS10555 49ac3e5d2a267805d6bd01c7175d8e98 90 Pfam PF00072 Response regulator receiver domain 31 87 2.0E-11 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS10555 49ac3e5d2a267805d6bd01c7175d8e98 90 SUPERFAMILY SSF52172 28 87 5.55E-17 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS04040 26e842d077e5fc72de3ffaf79c4fd0c7 116 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THSYN_RS04040 26e842d077e5fc72de3ffaf79c4fd0c7 116 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 107 1.2E-12 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS04040 26e842d077e5fc72de3ffaf79c4fd0c7 116 Gene3D G3DSA:3.10.20.30 2 116 2.0E-20 T 29-03-2018 IPR012675 Beta-grasp domain THSYN_RS04040 26e842d077e5fc72de3ffaf79c4fd0c7 116 SUPERFAMILY SSF54292 12 115 2.31E-12 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THSYN_RS12960 6a2cabaf438441d0a2b7430e6de766c6 108 Gene3D G3DSA:1.20.120.330 3 106 5.1E-17 T 29-03-2018 THSYN_RS12960 6a2cabaf438441d0a2b7430e6de766c6 108 Pfam PF05168 HEPN domain 5 97 7.3E-10 T 29-03-2018 IPR007842 HEPN domain THSYN_RS19330 115b3af2148395aa5979ec6fb0d469aa 357 PIRSF PIRSF029693 9 357 9.2E-127 T 29-03-2018 IPR016936 Uncharacterised conserved protein UCP029693 THSYN_RS19330 115b3af2148395aa5979ec6fb0d469aa 357 Pfam PF10095 Uncharacterized protein conserved in bacteria (DUF2333) 28 357 3.3E-160 T 29-03-2018 IPR016936 Uncharacterised conserved protein UCP029693 THSYN_RS14760 2ae731e9a07ff9422a714f341adcc850 535 Gene3D G3DSA:3.40.710.10 203 533 2.3E-71 T 29-03-2018 THSYN_RS14760 2ae731e9a07ff9422a714f341adcc850 535 Pfam PF00905 Penicillin binding protein transpeptidase domain 217 525 7.5E-52 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THSYN_RS14760 2ae731e9a07ff9422a714f341adcc850 535 Gene3D G3DSA:3.90.1310.10 107 202 1.9E-15 T 29-03-2018 THSYN_RS14760 2ae731e9a07ff9422a714f341adcc850 535 SUPERFAMILY SSF56601 154 530 1.21E-71 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS28155 0ce20e0c91192ecf098ac9877261719f 64 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 15 47 1.5E-7 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 THSYN_RS20930 20381dd8e81e135d71edeb4cfab126a6 86 Pfam PF03683 Uncharacterised protein family (UPF0175) 9 74 5.6E-18 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS32200 c03559f7fcf9a67fbe801020ecaddec8 271 Gene3D G3DSA:1.20.910.10 8 265 4.5E-35 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 THSYN_RS32200 c03559f7fcf9a67fbe801020ecaddec8 271 Pfam PF11251 Protein of unknown function (DUF3050) 20 249 2.9E-81 T 29-03-2018 IPR024423 Protein of unknown function DUF3050 THSYN_RS32200 c03559f7fcf9a67fbe801020ecaddec8 271 SUPERFAMILY SSF48613 123 254 1.19E-7 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 THSYN_RS32550 edee3305251c62ac256fe225ad571667 297 SUPERFAMILY SSF53474 19 286 1.68E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS32550 edee3305251c62ac256fe225ad571667 297 Gene3D G3DSA:3.40.50.1820 2 290 1.0E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS32550 edee3305251c62ac256fe225ad571667 297 TIGRFAM TIGR03056 bchO_mg_che_rel: putative magnesium chelatase accessory protein 13 285 2.0E-92 T 29-03-2018 IPR017497 Putative magnesium chelatase accessory protein KEGG: 00860+6.6.1.1|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS32550 edee3305251c62ac256fe225ad571667 297 Pfam PF12697 Alpha/beta hydrolase family 41 282 9.4E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS32550 edee3305251c62ac256fe225ad571667 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 7.9E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS32550 edee3305251c62ac256fe225ad571667 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 235 249 7.9E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS32550 edee3305251c62ac256fe225ad571667 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 64 79 7.9E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS14135 bea908c89be4e38efbfde7ac804e8c85 475 Pfam PF00656 Caspase domain 4 153 9.7E-7 T 29-03-2018 THSYN_RS14135 bea908c89be4e38efbfde7ac804e8c85 475 Gene3D G3DSA:3.40.50.1460 2 246 7.3E-26 T 29-03-2018 THSYN_RS14135 bea908c89be4e38efbfde7ac804e8c85 475 Gene3D G3DSA:3.40.50.300 267 446 4.2E-10 T 29-03-2018 THSYN_RS14135 bea908c89be4e38efbfde7ac804e8c85 475 SUPERFAMILY SSF52540 269 470 8.77E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14135 bea908c89be4e38efbfde7ac804e8c85 475 SUPERFAMILY SSF52129 4 203 6.07E-5 T 29-03-2018 IPR029030 Caspase-like domain THSYN_RS08755 fe2f4ec662201230a5facb671ecee421 238 Pfam PF01797 Transposase IS200 like 14 124 5.5E-16 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS08755 fe2f4ec662201230a5facb671ecee421 238 SUPERFAMILY SSF143422 3 127 3.92E-30 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS08755 fe2f4ec662201230a5facb671ecee421 238 Gene3D G3DSA:3.30.70.1290 5 130 3.6E-25 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS08755 fe2f4ec662201230a5facb671ecee421 238 SMART SM01321 9 124 3.3E-39 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS02490 442d01c5335a3c96410a7ba8ea8ba7d1 784 Pfam PF03958 Bacterial type II/III secretion system short domain 215 273 6.5E-7 T 29-03-2018 IPR005644 NolW-like THSYN_RS02490 442d01c5335a3c96410a7ba8ea8ba7d1 784 Pfam PF03958 Bacterial type II/III secretion system short domain 357 501 5.5E-7 T 29-03-2018 IPR005644 NolW-like THSYN_RS02490 442d01c5335a3c96410a7ba8ea8ba7d1 784 Pfam PF03958 Bacterial type II/III secretion system short domain 281 347 7.1E-8 T 29-03-2018 IPR005644 NolW-like THSYN_RS02490 442d01c5335a3c96410a7ba8ea8ba7d1 784 PRINTS PR00811 Bacterial general secretion pathway protein D signature 594 618 1.3E-13 T 29-03-2018 IPR001775 GspD/PilQ family THSYN_RS02490 442d01c5335a3c96410a7ba8ea8ba7d1 784 PRINTS PR00811 Bacterial general secretion pathway protein D signature 748 762 1.3E-13 T 29-03-2018 IPR001775 GspD/PilQ family THSYN_RS02490 442d01c5335a3c96410a7ba8ea8ba7d1 784 PRINTS PR00811 Bacterial general secretion pathway protein D signature 502 512 1.3E-13 T 29-03-2018 IPR001775 GspD/PilQ family THSYN_RS02490 442d01c5335a3c96410a7ba8ea8ba7d1 784 PRINTS PR00811 Bacterial general secretion pathway protein D signature 725 743 1.3E-13 T 29-03-2018 IPR001775 GspD/PilQ family THSYN_RS02490 442d01c5335a3c96410a7ba8ea8ba7d1 784 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 116 769 4.4E-148 T 29-03-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 THSYN_RS02490 442d01c5335a3c96410a7ba8ea8ba7d1 784 Pfam PF00263 Bacterial type II and III secretion system protein 598 760 1.4E-45 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 THSYN_RS33235 025b82699e7d3eb763c8669db5782c0b 221 TIGRFAM TIGR03830 CxxCG_CxxCG_HTH: putative zinc finger/helix-turn-helix protein, YgiT family 8 138 3.5E-32 T 29-03-2018 IPR022452 Antitoxin MqsA THSYN_RS33235 025b82699e7d3eb763c8669db5782c0b 221 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 8 53 1.1E-4 T 29-03-2018 IPR022453 Zinc finger, MqsA-type THSYN_RS33235 025b82699e7d3eb763c8669db5782c0b 221 Pfam PF15731 Antitoxin component of bacterial toxin-antitoxin system, MqsA 8 136 5.2E-24 T 29-03-2018 IPR032758 Antitoxin MqsA/HigA-2 THSYN_RS33235 025b82699e7d3eb763c8669db5782c0b 221 Gene3D G3DSA:1.10.260.40 53 141 2.0E-9 T 29-03-2018 THSYN_RS33235 025b82699e7d3eb763c8669db5782c0b 221 SUPERFAMILY SSF47413 84 140 1.18E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS14205 c252d9e9ae95a8e93536a2483e68f465 511 SUPERFAMILY SSF52540 7 246 3.85E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14205 c252d9e9ae95a8e93536a2483e68f465 511 TIGRFAM TIGR02655 circ_KaiC: circadian clock protein KaiC 11 491 2.4E-189 T 29-03-2018 IPR013503 Circadian clock KaiC, bacteria GO:0000287|GO:0003677|GO:0004674|GO:0005524|GO:0006355|GO:0042752 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 THSYN_RS14205 c252d9e9ae95a8e93536a2483e68f465 511 Pfam PF06745 KaiC 262 474 1.2E-40 T 29-03-2018 IPR014774 KaiC-like domain THSYN_RS14205 c252d9e9ae95a8e93536a2483e68f465 511 Pfam PF06745 KaiC 14 243 7.0E-68 T 29-03-2018 IPR014774 KaiC-like domain THSYN_RS14205 c252d9e9ae95a8e93536a2483e68f465 511 PIRSF PIRSF039117 1 499 1.7E-135 T 29-03-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 THSYN_RS14205 c252d9e9ae95a8e93536a2483e68f465 511 SUPERFAMILY SSF52540 250 485 2.52E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14205 c252d9e9ae95a8e93536a2483e68f465 511 Gene3D G3DSA:3.40.50.300 11 247 6.1E-32 T 29-03-2018 THSYN_RS14205 c252d9e9ae95a8e93536a2483e68f465 511 Gene3D G3DSA:3.40.50.300 255 481 5.3E-32 T 29-03-2018 THSYN_RS15570 0bd638fed9bee27656f8b0981de47437 173 Pfam PF08847 Chlororespiratory reduction 6 28 95 9.4E-6 T 29-03-2018 IPR014946 Protein chlororespiratory reduction 6 THSYN_RS12565 fff40ba8972cb8cb9bf913d7a95e88ed 124 Gene3D G3DSA:1.10.10.10 3 112 3.8E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS05235 1f7fb2042f8540db3a9f95262c75f687 189 Gene3D G3DSA:2.60.60.30 19 186 2.0E-64 T 29-03-2018 THSYN_RS05235 1f7fb2042f8540db3a9f95262c75f687 189 Pfam PF02342 TerD domain 1 187 3.0E-79 T 29-03-2018 IPR003325 TerD domain GO:0006950 THSYN_RS10495 547c27cc8617fbfefc5b45246664f864 77 Pfam PF13711 Domain of unknown function (DUF4160) 9 70 4.8E-16 T 29-03-2018 IPR025427 Protein of unknown function DUF4160 THSYN_RS32555 1c9d0dcf9f6d880a64a453b9245a0d8e 437 Pfam PF00534 Glycosyl transferases group 1 299 352 2.5E-6 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS32555 1c9d0dcf9f6d880a64a453b9245a0d8e 437 SUPERFAMILY SSF53756 21 422 8.64E-37 T 29-03-2018 THSYN_RS32555 1c9d0dcf9f6d880a64a453b9245a0d8e 437 Gene3D G3DSA:3.40.50.2000 235 413 2.0E-18 T 29-03-2018 THSYN_RS32555 1c9d0dcf9f6d880a64a453b9245a0d8e 437 Gene3D G3DSA:3.40.50.2000 13 234 7.1E-9 T 29-03-2018 THSYN_RS32555 1c9d0dcf9f6d880a64a453b9245a0d8e 437 Pfam PF13579 Glycosyl transferase 4-like domain 33 211 5.1E-7 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS00080 caccda20a330498c93c17bc5d6744b23 692 Pfam PF12161 HsdM N-terminal domain 20 161 1.6E-24 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THSYN_RS00080 caccda20a330498c93c17bc5d6744b23 692 Pfam PF02384 N-6 DNA Methylase 174 393 8.4E-50 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS00080 caccda20a330498c93c17bc5d6744b23 692 Pfam PF02384 N-6 DNA Methylase 416 497 2.0E-14 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS00080 caccda20a330498c93c17bc5d6744b23 692 Gene3D G3DSA:3.40.50.150 194 649 3.3E-52 T 29-03-2018 THSYN_RS00080 caccda20a330498c93c17bc5d6744b23 692 SUPERFAMILY SSF53335 343 500 6.52E-104 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS00080 caccda20a330498c93c17bc5d6744b23 692 SUPERFAMILY SSF53335 611 690 6.52E-104 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS00080 caccda20a330498c93c17bc5d6744b23 692 SUPERFAMILY SSF53335 89 312 6.52E-104 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS00080 caccda20a330498c93c17bc5d6744b23 692 SUPERFAMILY SSF53335 18 57 6.52E-104 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS00080 caccda20a330498c93c17bc5d6744b23 692 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 359 383 5.4E-16 T 29-03-2018 THSYN_RS00080 caccda20a330498c93c17bc5d6744b23 692 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 196 212 5.4E-16 T 29-03-2018 THSYN_RS00080 caccda20a330498c93c17bc5d6744b23 692 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 298 310 5.4E-16 T 29-03-2018 THSYN_RS00080 caccda20a330498c93c17bc5d6744b23 692 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 220 234 5.4E-16 T 29-03-2018 THSYN_RS25785 7caa740b3eaf3042e9d1eb079f3db45e 273 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 5 269 3.4E-80 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 THSYN_RS25785 7caa740b3eaf3042e9d1eb079f3db45e 273 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 118 193 9.3E-9 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase THSYN_RS25785 7caa740b3eaf3042e9d1eb079f3db45e 273 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 7.5E-25 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 THSYN_RS25785 7caa740b3eaf3042e9d1eb079f3db45e 273 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 272 32.782 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 THSYN_RS25785 7caa740b3eaf3042e9d1eb079f3db45e 273 Gene3D G3DSA:3.40.50.10860 1 109 1.3E-39 T 29-03-2018 THSYN_RS25785 7caa740b3eaf3042e9d1eb079f3db45e 273 SUPERFAMILY SSF53223 3 102 8.63E-32 T 29-03-2018 THSYN_RS25785 7caa740b3eaf3042e9d1eb079f3db45e 273 Gene3D G3DSA:3.40.50.720 110 273 2.2E-30 T 29-03-2018 THSYN_RS25785 7caa740b3eaf3042e9d1eb079f3db45e 273 SUPERFAMILY SSF51735 103 270 2.75E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS13980 3a9225251643371d2e5466c64046ec26 306 Gene3D G3DSA:3.40.50.1000 160 297 1.3E-17 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS13980 3a9225251643371d2e5466c64046ec26 306 Gene3D G3DSA:3.40.50.1000 31 155 0.073 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS13980 3a9225251643371d2e5466c64046ec26 306 Pfam PF06189 5'-nucleotidase 41 302 6.1E-108 T 29-03-2018 IPR010394 5-nucleotidase GO:0000166|GO:0000287|GO:0005737|GO:0008253|GO:0009117 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821|Reactome: R-HSA-74259 THSYN_RS22405 dba1cafa54bdcdd99fd99627a3d85aab 219 PRINTS PR00773 GrpE protein signature 104 119 6.0E-5 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THSYN_RS22405 dba1cafa54bdcdd99fd99627a3d85aab 219 PRINTS PR00773 GrpE protein signature 197 216 6.0E-5 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THSYN_RS22405 dba1cafa54bdcdd99fd99627a3d85aab 219 SUPERFAMILY SSF51064 163 217 1.57E-9 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 THSYN_RS22405 dba1cafa54bdcdd99fd99627a3d85aab 219 Pfam PF01025 GrpE 44 217 2.1E-23 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THSYN_RS22405 dba1cafa54bdcdd99fd99627a3d85aab 219 Gene3D G3DSA:2.30.22.10 162 218 1.9E-13 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 THSYN_RS01925 546b2f3af68d620eeddb4fed00dfd732 244 Pfam PF07556 Protein of unknown function (DUF1538) 22 242 2.5E-66 T 29-03-2018 IPR011435 Protein of unknown function DUF1538 THSYN_RS19580 d59b5274d0901185b5b0bfa3d7a9497e 186 SUPERFAMILY SSF53474 9 99 7.87E-9 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS19580 d59b5274d0901185b5b0bfa3d7a9497e 186 Gene3D G3DSA:3.40.50.1820 8 169 5.9E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS04110 ef78c6097c2752ce37db4475a13767ef 229 Pfam PF00005 ABC transporter 24 172 3.6E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS04110 ef78c6097c2752ce37db4475a13767ef 229 SUPERFAMILY SSF52540 16 222 1.65E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04110 ef78c6097c2752ce37db4475a13767ef 229 Gene3D G3DSA:3.40.50.300 1 225 1.1E-59 T 29-03-2018 THSYN_RS04110 ef78c6097c2752ce37db4475a13767ef 229 SMART SM00382 32 221 1.3E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS04110 ef78c6097c2752ce37db4475a13767ef 229 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS25595 d4b2c3b81f2819c19fdb525a57419cd7 152 SUPERFAMILY SSF56436 10 100 5.42E-27 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS25595 d4b2c3b81f2819c19fdb525a57419cd7 152 Gene3D G3DSA:3.90.1580.10 2 75 1.7E-14 T 29-03-2018 THSYN_RS25595 d4b2c3b81f2819c19fdb525a57419cd7 152 Gene3D G3DSA:3.90.1580.10 76 110 3.4E-10 T 29-03-2018 THSYN_RS25595 d4b2c3b81f2819c19fdb525a57419cd7 152 Pfam PF03781 Sulfatase-modifying factor enzyme 1 10 109 7.7E-24 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS04205 670736af5881dff667ba0d24c8bd7bbe 78 Gene3D G3DSA:2.10.260.10 1 39 8.1E-13 T 29-03-2018 THSYN_RS04205 670736af5881dff667ba0d24c8bd7bbe 78 SUPERFAMILY SSF89447 1 74 3.49E-12 T 29-03-2018 THSYN_RS04205 670736af5881dff667ba0d24c8bd7bbe 78 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 36 1.9E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS04205 670736af5881dff667ba0d24c8bd7bbe 78 SMART SM00966 4 50 5.7E-8 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS20445 77cc8968532ffb217a1da6b6c03b68b6 330 Pfam PF04754 Putative transposase, YhgA-like 1 164 8.2E-29 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS32810 f0035e6ef863ddb21b84237b85698429 1026 Pfam PF04465 Protein of unknown function (DUF499) 116 363 2.5E-20 T 29-03-2018 IPR007555 Protein of unknown function DUF499 THSYN_RS32810 f0035e6ef863ddb21b84237b85698429 1026 Pfam PF13287 Fn3 associated 843 885 1.7E-5 T 29-03-2018 IPR026876 Fn3 associated repeat THSYN_RS32810 f0035e6ef863ddb21b84237b85698429 1026 Gene3D G3DSA:2.60.40.10 836 897 0.01 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS09065 dde383c1d3465811e5ab35254b11dab6 292 Pfam PF02361 Cobalt transport protein 46 252 4.4E-31 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component THSYN_RS09065 dde383c1d3465811e5ab35254b11dab6 292 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 49 247 1.0E-37 T 29-03-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 THSYN_RS23695 5cbccfbbd87622864a4f535962df9415 396 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 11 226 1.7E-39 T 29-03-2018 THSYN_RS23695 5cbccfbbd87622864a4f535962df9415 396 SUPERFAMILY SSF46565 345 395 8.24E-14 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS23695 5cbccfbbd87622864a4f535962df9415 396 Hamap MF_00468 Sulfate transporter CysZ [cysZ]. 5 244 24.534 T 29-03-2018 IPR022985 Sulfate transporter CysZ GO:0000103|GO:0005887|GO:0015116 THSYN_RS23695 5cbccfbbd87622864a4f535962df9415 396 Gene3D G3DSA:1.10.287.110 342 395 3.2E-13 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS23695 5cbccfbbd87622864a4f535962df9415 396 SMART SM00271 345 395 3.0E-5 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS16455 f20ff3a951c7e7a0b8fdc55a485ac338 312 SUPERFAMILY SSF53448 5 307 2.53E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS16455 f20ff3a951c7e7a0b8fdc55a485ac338 312 Gene3D G3DSA:3.90.550.10 2 214 4.4E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS16455 f20ff3a951c7e7a0b8fdc55a485ac338 312 Pfam PF00535 Glycosyl transferase family 2 7 172 4.7E-30 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS24695 e35c304fa84643fa5128c51a5edb64f0 391 Pfam PF01226 Formate/nitrite transporter 129 384 8.2E-73 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 THSYN_RS24695 e35c304fa84643fa5128c51a5edb64f0 391 Gene3D G3DSA:1.20.1080.10 118 389 3.7E-76 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 THSYN_RS02785 1c43a0373241741702b8a3b531490bf1 162 Pfam PF02643 Uncharacterized ACR, COG1430 53 158 2.3E-28 T 29-03-2018 IPR003795 Protein of unknown function DUF192 THSYN_RS26710 fab6304e3ddeee44ed9c096bd13a2d10 192 Pfam PF00578 AhpC/TSA family 41 154 9.3E-33 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THSYN_RS26710 fab6304e3ddeee44ed9c096bd13a2d10 192 ProSitePatterns PS00194 Thioredoxin family active site. 66 84 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THSYN_RS26710 fab6304e3ddeee44ed9c096bd13a2d10 192 SUPERFAMILY SSF52833 41 177 1.26E-44 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS26710 fab6304e3ddeee44ed9c096bd13a2d10 192 Gene3D G3DSA:3.40.30.10 20 175 1.9E-40 T 29-03-2018 THSYN_RS03010 de0fe828e0aedd62b75cd227bf041637 148 Gene3D G3DSA:3.10.129.10 1 140 4.9E-18 T 29-03-2018 THSYN_RS03010 de0fe828e0aedd62b75cd227bf041637 148 SUPERFAMILY SSF54637 6 140 2.49E-9 T 29-03-2018 IPR029069 HotDog domain THSYN_RS26840 4b370a597df31cd40618213cac05ac30 297 Gene3D G3DSA:3.90.550.10 1 216 2.2E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS26840 4b370a597df31cd40618213cac05ac30 297 Pfam PF00535 Glycosyl transferase family 2 6 158 7.0E-29 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS26840 4b370a597df31cd40618213cac05ac30 297 SUPERFAMILY SSF53448 3 242 7.7E-43 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS01920 9d1cde001591765552ea5533709fd87c 258 Pfam PF07556 Protein of unknown function (DUF1538) 22 246 2.8E-70 T 29-03-2018 IPR011435 Protein of unknown function DUF1538 THSYN_RS00470 07ffa06d8f5f73ffbb41038983c8aa1c 266 TIGRFAM TIGR03321 alt_F1F0_F0_B: alternate F1F0 ATPase, F0 subunit B 1 244 2.6E-93 T 29-03-2018 IPR017707 Alternate ATP synthase, F0 complex, subunit b THSYN_RS00470 07ffa06d8f5f73ffbb41038983c8aa1c 266 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 139 10.843 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THSYN_RS00470 07ffa06d8f5f73ffbb41038983c8aa1c 266 Pfam PF00430 ATP synthase B/B' CF(0) 10 137 7.5E-15 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THSYN_RS00470 07ffa06d8f5f73ffbb41038983c8aa1c 266 Pfam PF00213 ATP synthase delta (OSCP) subunit 173 241 2.9E-6 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS32275 f130a075185a87c11b7ed836d9ae3e85 365 Pfam PF13860 FlgD Ig-like domain 47 114 2.2E-11 T 29-03-2018 IPR025965 FlgD Ig-like domain THSYN_RS06775 d4ce40aed4c2814dd3f4a8c507182701 260 Pfam PF07702 UTRA domain 119 202 1.3E-8 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 THSYN_RS06775 d4ce40aed4c2814dd3f4a8c507182701 260 SUPERFAMILY SSF64288 118 202 4.4E-10 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain THSYN_RS06775 d4ce40aed4c2814dd3f4a8c507182701 260 Gene3D G3DSA:3.40.1410.10 80 245 3.8E-12 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain THSYN_RS06775 d4ce40aed4c2814dd3f4a8c507182701 260 Gene3D G3DSA:1.10.10.10 6 69 1.2E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS24355 cd01a97962724dccac4decb95cc1b5c9 416 Pfam PF10082 Putative beta-barrel porin 2 29 414 6.0E-26 T 29-03-2018 IPR018759 Putative beta-barrel porin 2 THSYN_RS24355 cd01a97962724dccac4decb95cc1b5c9 416 Gene3D G3DSA:2.40.160.60 300 413 0.026 T 29-03-2018 THSYN_RS24355 cd01a97962724dccac4decb95cc1b5c9 416 Gene3D G3DSA:2.40.160.10 20 299 6.0E-4 T 29-03-2018 THSYN_RS12790 da3e3ff88da7074ed27210472fcbeafa 321 Pfam PF00146 NADH dehydrogenase 17 309 8.6E-38 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS12955 853440409091b43c5dac8cf8391f56aa 156 Gene3D G3DSA:3.40.50.1010 3 143 3.8E-14 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS12955 853440409091b43c5dac8cf8391f56aa 156 SUPERFAMILY SSF88723 5 128 2.06E-7 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS33070 7fdbdd9b467cecc1fa575dbc11d0fbf6 117 Pfam PF05717 IS66 Orf2 like protein 9 107 5.1E-40 T 29-03-2018 IPR008878 Transposase IS66, Orf2 THSYN_RS26980 ac6f9ec8d0a6bc2149894a78642c7c3a 981 Pfam PF04465 Protein of unknown function (DUF499) 156 533 9.6E-21 T 29-03-2018 IPR007555 Protein of unknown function DUF499 THSYN_RS06795 f39d7f52f117ae42793800a6039d39e9 239 Pfam PF00535 Glycosyl transferase family 2 9 125 1.9E-30 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS06795 f39d7f52f117ae42793800a6039d39e9 239 SUPERFAMILY SSF53448 8 220 1.41E-48 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS06795 f39d7f52f117ae42793800a6039d39e9 239 Gene3D G3DSA:3.90.550.10 4 233 2.7E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS19885 16b30b74dbfa2abadc53cd78b6eeabb7 151 Gene3D G3DSA:1.20.120.610 1 151 1.4E-23 T 29-03-2018 THSYN_RS19885 16b30b74dbfa2abadc53cd78b6eeabb7 151 Pfam PF00137 ATP synthase subunit C 88 147 2.7E-14 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 THSYN_RS19885 16b30b74dbfa2abadc53cd78b6eeabb7 151 PRINTS PR00124 ATP synthase C subunit signature 85 104 8.0E-5 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS19885 16b30b74dbfa2abadc53cd78b6eeabb7 151 PRINTS PR00124 ATP synthase C subunit signature 123 148 8.0E-5 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS19885 16b30b74dbfa2abadc53cd78b6eeabb7 151 SUPERFAMILY SSF81333 80 150 8.63E-15 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 THSYN_RS26995 78f9a2830c33fddd6e1ced3acc8c9081 1007 Pfam PF06634 Protein of unknown function (DUF1156) 13 65 1.0E-22 T 29-03-2018 IPR009537 Domain of unknown function DUF1156 THSYN_RS26995 78f9a2830c33fddd6e1ced3acc8c9081 1007 SUPERFAMILY SSF53335 128 192 9.2E-7 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS26995 78f9a2830c33fddd6e1ced3acc8c9081 1007 Gene3D G3DSA:3.40.50.150 75 702 6.8E-32 T 29-03-2018 THSYN_RS26995 78f9a2830c33fddd6e1ced3acc8c9081 1007 SUPERFAMILY SSF53335 614 677 4.32E-8 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS26995 78f9a2830c33fddd6e1ced3acc8c9081 1007 SUPERFAMILY SSF53335 544 568 4.32E-8 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS20005 422ee801f24e365d12f1ff3719a25d5b 209 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 7 204 1.6E-32 T 29-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS20005 422ee801f24e365d12f1ff3719a25d5b 209 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 5 208 18.499 T 29-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS20005 422ee801f24e365d12f1ff3719a25d5b 209 Gene3D G3DSA:1.20.5.340 1 194 2.9E-4 T 29-03-2018 THSYN_RS20005 422ee801f24e365d12f1ff3719a25d5b 209 Pfam PF01813 ATP synthase subunit D 14 202 5.1E-42 T 29-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS13265 41d5cade58dfe00e1ea38385620c9f27 162 SUPERFAMILY SSF54928 10 114 7.96E-9 T 29-03-2018 IPR000504 RNA recognition motif domain GO:0003676 THSYN_RS13265 41d5cade58dfe00e1ea38385620c9f27 162 Gene3D G3DSA:3.30.70.330 10 121 3.4E-9 T 29-03-2018 THSYN_RS08795 7ad39e6e1025d804be573e5a28edb329 499 Gene3D G3DSA:3.30.930.10 166 499 9.2E-99 T 29-03-2018 THSYN_RS08795 7ad39e6e1025d804be573e5a28edb329 499 Pfam PF01336 OB-fold nucleic acid binding domain 62 140 2.6E-15 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 THSYN_RS08795 7ad39e6e1025d804be573e5a28edb329 499 Pfam PF00152 tRNA synthetases class II (D, K and N) 156 495 6.1E-81 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THSYN_RS08795 7ad39e6e1025d804be573e5a28edb329 499 SUPERFAMILY SSF50249 7 149 1.14E-41 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold THSYN_RS08795 7ad39e6e1025d804be573e5a28edb329 499 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 15 498 44.326 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THSYN_RS08795 7ad39e6e1025d804be573e5a28edb329 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 238 251 3.6E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THSYN_RS08795 7ad39e6e1025d804be573e5a28edb329 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 193 203 3.6E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THSYN_RS08795 7ad39e6e1025d804be573e5a28edb329 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 256 273 3.6E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THSYN_RS08795 7ad39e6e1025d804be573e5a28edb329 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 3.6E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THSYN_RS08795 7ad39e6e1025d804be573e5a28edb329 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 380 396 3.6E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THSYN_RS08795 7ad39e6e1025d804be573e5a28edb329 499 SUPERFAMILY SSF55681 156 496 1.29E-116 T 29-03-2018 THSYN_RS08795 7ad39e6e1025d804be573e5a28edb329 499 Gene3D G3DSA:2.40.50.140 9 148 1.2E-34 T 29-03-2018 THSYN_RS08795 7ad39e6e1025d804be573e5a28edb329 499 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 10 498 2.3E-209 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THSYN_RS12720 62317cb73ce6c4b42caeb65ea7afee25 310 SUPERFAMILY SSF158682 190 307 1.01E-19 T 29-03-2018 THSYN_RS12720 62317cb73ce6c4b42caeb65ea7afee25 310 Pfam PF04391 Protein of unknown function (DUF533) 115 307 1.2E-45 T 29-03-2018 IPR007486 Inner membrane protein YebE THSYN_RS12720 62317cb73ce6c4b42caeb65ea7afee25 310 Gene3D G3DSA:1.10.3680.10 177 308 1.2E-15 T 29-03-2018 IPR029024 TerB-like THSYN_RS30565 b31aead9412945a053627901d1eb6224 185 Pfam PF01292 Prokaryotic cytochrome b561 6 181 2.6E-25 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THSYN_RS30565 b31aead9412945a053627901d1eb6224 185 Gene3D G3DSA:1.20.950.20 2 184 3.4E-28 T 29-03-2018 THSYN_RS30565 b31aead9412945a053627901d1eb6224 185 SUPERFAMILY SSF81342 6 181 6.83E-29 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THSYN_RS16175 76c75180f73ffc75c922d6abe5806e41 332 Gene3D G3DSA:3.30.160.60 75 107 4.0E-9 T 29-03-2018 THSYN_RS16175 76c75180f73ffc75c922d6abe5806e41 332 Gene3D G3DSA:3.30.160.60 302 332 2.7E-12 T 29-03-2018 THSYN_RS16175 76c75180f73ffc75c922d6abe5806e41 332 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 6 328 1.8E-81 T 29-03-2018 IPR003770 Endolytic murein transglycosylase THSYN_RS16175 76c75180f73ffc75c922d6abe5806e41 332 Pfam PF02618 YceG-like family 41 326 6.5E-80 T 29-03-2018 IPR003770 Endolytic murein transglycosylase THSYN_RS16175 76c75180f73ffc75c922d6abe5806e41 332 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 2 332 34.327 T 29-03-2018 IPR003770 Endolytic murein transglycosylase THSYN_RS16725 0d1833b728a92a51e83838888282a120 216 Pfam PF09360 Iron-binding zinc finger CDGSH type 90 133 2.4E-12 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THSYN_RS16725 0d1833b728a92a51e83838888282a120 216 Pfam PF09360 Iron-binding zinc finger CDGSH type 165 209 4.3E-17 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THSYN_RS16725 0d1833b728a92a51e83838888282a120 216 SMART SM00704 98 139 1.1E-7 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THSYN_RS16725 0d1833b728a92a51e83838888282a120 216 SMART SM00704 178 214 1.1E-6 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THSYN_RS16725 0d1833b728a92a51e83838888282a120 216 Pfam PF06902 Divergent 4Fe-4S mono-cluster 9 72 5.7E-20 T 29-03-2018 IPR010693 Divergent 4Fe-4S mono-cluster THSYN_RS33055 386ee6b0b78386fc5f1b123899f3d843 83 Pfam PF03683 Uncharacterised protein family (UPF0175) 12 80 9.7E-22 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS07525 1a493cb4b820b644844166c9b7a052f6 329 PRINTS PR00990 Ribokinase signature 55 74 1.3E-5 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 THSYN_RS07525 1a493cb4b820b644844166c9b7a052f6 329 PRINTS PR00990 Ribokinase signature 243 254 1.3E-5 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 THSYN_RS07525 1a493cb4b820b644844166c9b7a052f6 329 PRINTS PR00990 Ribokinase signature 205 220 1.3E-5 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 THSYN_RS07525 1a493cb4b820b644844166c9b7a052f6 329 Pfam PF00294 pfkB family carbohydrate kinase 35 317 5.4E-59 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB THSYN_RS07525 1a493cb4b820b644844166c9b7a052f6 329 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 272 285 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 THSYN_RS07525 1a493cb4b820b644844166c9b7a052f6 329 SUPERFAMILY SSF53613 1 317 4.83E-79 T 29-03-2018 IPR029056 Ribokinase-like THSYN_RS07525 1a493cb4b820b644844166c9b7a052f6 329 Gene3D G3DSA:3.40.1190.20 2 328 7.6E-69 T 29-03-2018 IPR029056 Ribokinase-like THSYN_RS00585 eb31611c7cf0f1d6ce2413dfb4030f2b 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 224 4.3E-13 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS00585 eb31611c7cf0f1d6ce2413dfb4030f2b 242 Gene3D G3DSA:1.10.10.10 123 230 7.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS00585 eb31611c7cf0f1d6ce2413dfb4030f2b 242 SMART SM00448 5 115 5.4E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00585 eb31611c7cf0f1d6ce2413dfb4030f2b 242 SUPERFAMILY SSF52172 3 131 5.55E-34 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS00585 eb31611c7cf0f1d6ce2413dfb4030f2b 242 SMART SM00862 151 224 6.9E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THSYN_RS00585 eb31611c7cf0f1d6ce2413dfb4030f2b 242 Pfam PF00072 Response regulator receiver domain 7 116 5.5E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS00585 eb31611c7cf0f1d6ce2413dfb4030f2b 242 SUPERFAMILY SSF46894 132 225 3.97E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THSYN_RS00585 eb31611c7cf0f1d6ce2413dfb4030f2b 242 Gene3D G3DSA:3.40.50.2300 1 122 1.5E-31 T 29-03-2018 THSYN_RS23025 10b3403c3f1fa6624cce6eaf3e95e242 146 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 3 146 37.21 T 29-03-2018 IPR008228 Uncharacterised conserved protein UCP006173 THSYN_RS23025 10b3403c3f1fa6624cce6eaf3e95e242 146 PIRSF PIRSF006173 1 145 2.6E-59 T 29-03-2018 IPR008228 Uncharacterised conserved protein UCP006173 THSYN_RS23025 10b3403c3f1fa6624cce6eaf3e95e242 146 Pfam PF03692 Putative zinc- or iron-chelating domain 25 93 2.2E-7 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein THSYN_RS03710 6d335570ae1d655da7a3dfbfe8a85d62 482 Gene3D G3DSA:3.40.50.300 116 362 4.8E-21 T 29-03-2018 THSYN_RS03710 6d335570ae1d655da7a3dfbfe8a85d62 482 SUPERFAMILY SSF52540 121 291 1.86E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03710 6d335570ae1d655da7a3dfbfe8a85d62 482 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 126 212 2.9E-7 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THSYN_RS29285 de71d0e120509942fbdaad26afffa307 73 Pfam PF01809 Haemolytic domain 3 68 6.4E-31 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor THSYN_RS29285 de71d0e120509942fbdaad26afffa307 73 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 25.561 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor THSYN_RS29285 de71d0e120509942fbdaad26afffa307 73 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 1.0E-17 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor THSYN_RS29285 de71d0e120509942fbdaad26afffa307 73 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 73 6.2E-29 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor THSYN_RS29285 de71d0e120509942fbdaad26afffa307 73 SMART SM01234 1 68 1.1E-44 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor THSYN_RS01625 0574e4bb4cfa78a6cd8b2c1ec84eb0cf 871 Gene3D G3DSA:3.40.50.300 253 514 1.3E-6 T 29-03-2018 THSYN_RS01625 0574e4bb4cfa78a6cd8b2c1ec84eb0cf 871 SUPERFAMILY SSF52540 245 430 2.77E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02940 b0e71588ddefad34b5a87f6757759c71 381 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 284 362 5.4E-11 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THSYN_RS02940 b0e71588ddefad34b5a87f6757759c71 381 Gene3D G3DSA:3.40.47.10 198 381 2.0E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS02940 b0e71588ddefad34b5a87f6757759c71 381 Gene3D G3DSA:3.40.47.10 1 197 1.9E-20 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS02940 b0e71588ddefad34b5a87f6757759c71 381 SUPERFAMILY SSF53901 284 369 7.61E-22 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS02940 b0e71588ddefad34b5a87f6757759c71 381 SUPERFAMILY SSF53901 60 241 7.61E-22 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 THSYN_RS17480 946ab44a66b4c5b6dc9ab05d6aae2b57 248 Gene3D G3DSA:3.90.1570.10 18 167 1.8E-23 T 29-03-2018 THSYN_RS17480 946ab44a66b4c5b6dc9ab05d6aae2b57 248 Pfam PF05685 Putative restriction endonuclease 32 152 1.9E-17 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS17480 946ab44a66b4c5b6dc9ab05d6aae2b57 248 SUPERFAMILY SSF52980 4 167 2.68E-31 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS22860 e30aeca94d344feb49c2e8b23aec83b1 95 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 4 80 5.1E-30 T 29-03-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 THSYN_RS22860 e30aeca94d344feb49c2e8b23aec83b1 95 Pfam PF01381 Helix-turn-helix 12 64 3.7E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS22860 e30aeca94d344feb49c2e8b23aec83b1 95 SUPERFAMILY SSF47413 7 88 1.49E-27 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS22860 e30aeca94d344feb49c2e8b23aec83b1 95 Gene3D G3DSA:1.10.260.40 2 81 2.7E-14 T 29-03-2018 THSYN_RS22860 e30aeca94d344feb49c2e8b23aec83b1 95 SMART SM00530 11 66 3.9E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS19035 7dd1745bf0f118675342e79fddbae3d9 216 SUPERFAMILY SSF103501 6 200 4.05E-25 T 29-03-2018 IPR023234 NarG-like domain THSYN_RS19035 7dd1745bf0f118675342e79fddbae3d9 216 Gene3D G3DSA:1.20.950.20 2 202 5.3E-15 T 29-03-2018 THSYN_RS30485 cae5f01efbf9ebdaac0fab8e9261631e 209 Pfam PF01464 Transglycosylase SLT domain 86 180 5.8E-21 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 THSYN_RS30485 cae5f01efbf9ebdaac0fab8e9261631e 209 SUPERFAMILY SSF53955 77 202 4.22E-41 T 29-03-2018 IPR023346 Lysozyme-like domain THSYN_RS30485 cae5f01efbf9ebdaac0fab8e9261631e 209 Gene3D G3DSA:1.10.530.10 19 208 5.5E-40 T 29-03-2018 THSYN_RS28310 bbf7b3e2ca96e8b119b0696f48dc8cbf 442 Pfam PF02754 Cysteine-rich domain 319 405 4.5E-16 T 29-03-2018 IPR004017 Cysteine-rich domain THSYN_RS28310 bbf7b3e2ca96e8b119b0696f48dc8cbf 442 Gene3D G3DSA:3.30.70.20 20 50 0.0046 T 29-03-2018 THSYN_RS28310 bbf7b3e2ca96e8b119b0696f48dc8cbf 442 Gene3D G3DSA:3.30.70.20 118 423 0.0043 T 29-03-2018 THSYN_RS28310 bbf7b3e2ca96e8b119b0696f48dc8cbf 442 SUPERFAMILY SSF46548 36 141 1.29E-15 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS28310 bbf7b3e2ca96e8b119b0696f48dc8cbf 442 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 110 121 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS28310 bbf7b3e2ca96e8b119b0696f48dc8cbf 442 Gene3D G3DSA:3.30.70.20 51 117 1.3E-9 T 29-03-2018 THSYN_RS28310 bbf7b3e2ca96e8b119b0696f48dc8cbf 442 Pfam PF13183 4Fe-4S dicluster domain 37 124 7.2E-11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS15955 e4925b36a67d5c281d43d5c07dd054d6 514 Gene3D G3DSA:3.40.50.150 181 512 1.8E-39 T 29-03-2018 THSYN_RS15955 e4925b36a67d5c281d43d5c07dd054d6 514 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 317 323 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS15955 e4925b36a67d5c281d43d5c07dd054d6 514 SUPERFAMILY SSF53335 362 508 7.95E-58 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS15955 e4925b36a67d5c281d43d5c07dd054d6 514 SUPERFAMILY SSF53335 30 328 7.95E-58 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS15955 e4925b36a67d5c281d43d5c07dd054d6 514 Pfam PF02384 N-6 DNA Methylase 161 506 5.8E-27 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THSYN_RS15955 e4925b36a67d5c281d43d5c07dd054d6 514 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 376 400 9.8E-19 T 29-03-2018 THSYN_RS15955 e4925b36a67d5c281d43d5c07dd054d6 514 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 199 9.8E-19 T 29-03-2018 THSYN_RS15955 e4925b36a67d5c281d43d5c07dd054d6 514 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 225 239 9.8E-19 T 29-03-2018 THSYN_RS15955 e4925b36a67d5c281d43d5c07dd054d6 514 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 314 326 9.8E-19 T 29-03-2018 THSYN_RS14375 5ceb09a50832f1fc8b3b40e5616ca06c 279 Pfam PF01925 Sulfite exporter TauE/SafE 38 271 1.8E-37 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 THSYN_RS02320 7788f8f47109c0f4b0f3411888107fcd 325 Pfam PF04754 Putative transposase, YhgA-like 6 190 1.3E-45 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS14715 0f42eb86b8000e20f1628146bea72c88 109 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 105 2.6E-26 T 29-03-2018 THSYN_RS31785 73c2da254962d2255e3826e8b1874990 361 PIRSF PIRSF015268 11 353 4.6E-139 T 29-03-2018 IPR011204 Virulence protein RhuM-like THSYN_RS31785 73c2da254962d2255e3826e8b1874990 361 Pfam PF13310 Virulence protein RhuM family 78 326 3.8E-107 T 29-03-2018 IPR011204 Virulence protein RhuM-like THSYN_RS31330 2356fd943aeefa5998b9d64521e25ccd 303 SUPERFAMILY SSF159245 5 280 3.14E-51 T 29-03-2018 THSYN_RS14445 3eaed2bfb918b1dae323d7a360d76333 328 Gene3D G3DSA:3.40.50.300 35 164 1.1E-7 T 29-03-2018 THSYN_RS14445 3eaed2bfb918b1dae323d7a360d76333 328 SUPERFAMILY SSF52540 41 129 4.85E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09950 8318620f2832e39b82a17a6cca080639 485 Gene3D G3DSA:3.40.50.300 203 484 9.2E-11 T 29-03-2018 THSYN_RS09950 8318620f2832e39b82a17a6cca080639 485 SUPERFAMILY SSF52540 269 388 9.81E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09950 8318620f2832e39b82a17a6cca080639 485 SUPERFAMILY SSF52540 213 237 9.81E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16405 70339eeeefb81460e58eb61b3a186da2 464 Gene3D G3DSA:3.40.50.10140 2 129 8.7E-15 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS16405 70339eeeefb81460e58eb61b3a186da2 464 Pfam PF13676 TIR domain 7 114 2.6E-16 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS16405 70339eeeefb81460e58eb61b3a186da2 464 SUPERFAMILY SSF52200 3 119 4.32E-15 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS08165 cfb676e8973e4e5a2a6e05664a79b781 323 Gene3D G3DSA:1.10.10.10 1 65 2.6E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS08165 cfb676e8973e4e5a2a6e05664a79b781 323 Pfam PF13280 WYL domain 148 318 2.3E-36 T 29-03-2018 IPR026881 WYL domain THSYN_RS10025 4a9c54befc39ab9dcabcd6398945d06f 795 Gene3D G3DSA:2.60.500.10 479 572 0.054 T 29-03-2018 THSYN_RS10025 4a9c54befc39ab9dcabcd6398945d06f 795 Gene3D G3DSA:2.60.500.10 366 459 0.14 T 29-03-2018 THSYN_RS10025 4a9c54befc39ab9dcabcd6398945d06f 795 Pfam PF03781 Sulfatase-modifying factor enzyme 1 641 728 3.4E-5 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS07995 2f262f72a7d35d845bfcd3311e6eb237 389 Pfam PF00999 Sodium/hydrogen exchanger family 15 366 4.0E-41 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 THSYN_RS07995 2f262f72a7d35d845bfcd3311e6eb237 389 Gene3D G3DSA:1.20.91.10 227 308 2.2E-7 T 29-03-2018 THSYN_RS08505 3cf680e26d3c7675f876cf4038d8ffb4 169 Gene3D G3DSA:3.30.450.20 22 149 6.0E-5 T 29-03-2018 THSYN_RS08505 3cf680e26d3c7675f876cf4038d8ffb4 169 Pfam PF08670 MEKHLA domain 19 158 8.4E-50 T 29-03-2018 IPR013978 MEKHLA THSYN_RS08505 3cf680e26d3c7675f876cf4038d8ffb4 169 SUPERFAMILY SSF55785 53 133 3.81E-5 T 29-03-2018 IPR000014 PAS domain THSYN_RS00465 2921fdfa8829528c5948af0cff2daa58 93 Hamap MF_01396 ATP synthase subunit c [atpH]. 12 77 13.259 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00465 2921fdfa8829528c5948af0cff2daa58 93 Gene3D G3DSA:1.20.20.10 6 79 1.5E-15 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 THSYN_RS00465 2921fdfa8829528c5948af0cff2daa58 93 PRINTS PR00124 ATP synthase C subunit signature 35 50 3.6E-10 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00465 2921fdfa8829528c5948af0cff2daa58 93 PRINTS PR00124 ATP synthase C subunit signature 14 33 3.6E-10 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00465 2921fdfa8829528c5948af0cff2daa58 93 PRINTS PR00124 ATP synthase C subunit signature 52 77 3.6E-10 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THSYN_RS00465 2921fdfa8829528c5948af0cff2daa58 93 Pfam PF00137 ATP synthase subunit C 15 76 1.0E-12 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 THSYN_RS00465 2921fdfa8829528c5948af0cff2daa58 93 TIGRFAM TIGR03322 alt_F1F0_F0_C: alternate F1F0 ATPase, F0 subunit C 2 87 2.3E-49 T 29-03-2018 IPR017708 Alternate ATP synthase, F0 complex, subunit C, bacterial/archaeal THSYN_RS00465 2921fdfa8829528c5948af0cff2daa58 93 SUPERFAMILY SSF81333 6 81 1.96E-16 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 THSYN_RS20480 76e171e89c63d1e84f732721920d13e1 143 SUPERFAMILY SSF53098 4 141 1.9E-56 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS20480 76e171e89c63d1e84f732721920d13e1 143 Gene3D G3DSA:3.30.420.10 1 143 1.1E-50 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS20480 76e171e89c63d1e84f732721920d13e1 143 Pfam PF00075 RNase H 4 141 4.3E-48 T 29-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 THSYN_RS20480 76e171e89c63d1e84f732721920d13e1 143 Hamap MF_00042 Ribonuclease H [rnhA]. 2 143 33.521 T 29-03-2018 IPR022892 Ribonuclease HI GO:0004523 THSYN_RS19080 3cff30120b88b630dfc9ebaa2e112661 288 SUPERFAMILY SSF111321 1 277 2.35E-78 T 29-03-2018 IPR002791 Domain of unknown function DUF89 THSYN_RS19080 3cff30120b88b630dfc9ebaa2e112661 288 Pfam PF01937 Protein of unknown function DUF89 5 272 1.6E-49 T 29-03-2018 IPR002791 Domain of unknown function DUF89 THSYN_RS19080 3cff30120b88b630dfc9ebaa2e112661 288 PIRSF PIRSF006593 1 281 5.7E-82 T 29-03-2018 IPR014444 Uncharacterised conserved protein UCP006593 THSYN_RS19425 d9567fcfc2ec9bf9f227d88ae361a4df 97 SUPERFAMILY SSF46689 2 74 1.09E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS19425 d9567fcfc2ec9bf9f227d88ae361a4df 97 Gene3D G3DSA:1.10.10.10 8 69 1.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19425 d9567fcfc2ec9bf9f227d88ae361a4df 97 Pfam PF04255 Protein of unknown function (DUF433) 8 62 4.4E-22 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS10580 332338869aff3c4bb9c901dc80a1892b 592 Pfam PF09820 Predicted AAA-ATPase 4 305 7.4E-66 T 29-03-2018 IPR018631 AAA-ATPase-like domain THSYN_RS19205 9e4d40b9cb3ec3003af2aafe5411535e 270 Gene3D G3DSA:1.10.3470.10 3 262 1.0E-4 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like THSYN_RS19205 9e4d40b9cb3ec3003af2aafe5411535e 270 Pfam PF00950 ABC 3 transport family 15 248 2.2E-13 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 THSYN_RS19205 9e4d40b9cb3ec3003af2aafe5411535e 270 SUPERFAMILY SSF81345 10 249 1.29E-13 T 29-03-2018 IPR029022 ABC transporter, BtuC-like THSYN_RS01405 d54567e44c9f71168ccf7b2484a6ad95 119 SUPERFAMILY SSF81301 32 116 2.72E-16 T 29-03-2018 THSYN_RS01405 d54567e44c9f71168ccf7b2484a6ad95 119 Pfam PF01909 Nucleotidyltransferase domain 42 109 3.8E-8 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS01405 d54567e44c9f71168ccf7b2484a6ad95 119 Gene3D G3DSA:3.30.460.10 21 119 2.0E-14 T 29-03-2018 THSYN_RS01405 d54567e44c9f71168ccf7b2484a6ad95 119 PIRSF PIRSF020217 6 119 1.9E-26 T 29-03-2018 IPR024700 Uncharacterised conserved protein, UCP020217 THSYN_RS07885 95719524ef831623e632ebe9f3835426 206 Pfam PF01627 Hpt domain 33 111 2.9E-8 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS07885 95719524ef831623e632ebe9f3835426 206 Gene3D G3DSA:1.20.120.160 7 127 2.1E-16 T 29-03-2018 THSYN_RS07885 95719524ef831623e632ebe9f3835426 206 SUPERFAMILY SSF47226 8 116 4.45E-18 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THSYN_RS22490 166c3e736802c1478b321e73df55182f 97 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 89 9.5E-8 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS32175 489d15b62673dbbfe3426452f5494fd3 464 Gene3D G3DSA:3.40.1010.10 4 119 3.2E-12 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS32175 489d15b62673dbbfe3426452f5494fd3 464 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 7 221 3.2E-41 T 29-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 THSYN_RS32175 489d15b62673dbbfe3426452f5494fd3 464 SUPERFAMILY SSF53335 277 430 4.89E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS32175 489d15b62673dbbfe3426452f5494fd3 464 Gene3D G3DSA:3.40.50.150 273 451 6.8E-27 T 29-03-2018 THSYN_RS32175 489d15b62673dbbfe3426452f5494fd3 464 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 209 5.9E-24 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS32175 489d15b62673dbbfe3426452f5494fd3 464 SUPERFAMILY SSF53790 6 225 9.03E-27 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS32175 489d15b62673dbbfe3426452f5494fd3 464 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 279 400 9.4E-34 T 29-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 THSYN_RS32175 489d15b62673dbbfe3426452f5494fd3 464 Gene3D G3DSA:3.30.950.10 120 232 4.0E-20 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 THSYN_RS32175 489d15b62673dbbfe3426452f5494fd3 464 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 279 397 1.2E-4 T 29-03-2018 THSYN_RS12020 4c2fde34cf3b0393a044921516d0f785 113 SUPERFAMILY SSF46785 47 98 8.81E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS12020 4c2fde34cf3b0393a044921516d0f785 113 Gene3D G3DSA:1.10.10.10 8 105 1.3E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS12020 4c2fde34cf3b0393a044921516d0f785 113 Pfam PF09339 IclR helix-turn-helix domain 52 94 5.5E-5 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THSYN_RS12480 78ac6b6a3df3315d7d90e2fa87e25b67 68 Pfam PF11211 Protein of unknown function (DUF2997) 7 51 9.0E-17 T 29-03-2018 IPR021375 Protein of unknown function DUF2997 THSYN_RS31960 9ea577c78cac2648d4d3dddd47c421d3 121 SUPERFAMILY SSF55248 8 96 6.02E-26 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 THSYN_RS31960 9ea577c78cac2648d4d3dddd47c421d3 121 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 7 94 7.2E-24 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 THSYN_RS31960 9ea577c78cac2648d4d3dddd47c421d3 121 Gene3D G3DSA:3.30.1360.20 1 97 4.0E-23 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 THSYN_RS01660 17238ce3a72463f7120a0d6bda063ff2 71 Gene3D G3DSA:2.10.260.10 2 46 4.8E-9 T 29-03-2018 THSYN_RS01660 17238ce3a72463f7120a0d6bda063ff2 71 SUPERFAMILY SSF89447 1 46 5.41E-10 T 29-03-2018 THSYN_RS01660 17238ce3a72463f7120a0d6bda063ff2 71 SMART SM00966 4 49 1.8E-5 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS01660 17238ce3a72463f7120a0d6bda063ff2 71 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 43 2.1E-12 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS28515 03ec00fa397b07132f9e4ebb1ee256d3 467 Pfam PF13372 Alginate export 121 449 8.4E-17 T 29-03-2018 IPR025388 Alginate export domain THSYN_RS28515 03ec00fa397b07132f9e4ebb1ee256d3 467 Gene3D G3DSA:2.40.160.20 5 448 2.7E-5 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THSYN_RS05590 2297bf3493ca58b1a084f37e9b53e520 109 SUPERFAMILY SSF81301 11 98 2.02E-14 T 29-03-2018 THSYN_RS05590 2297bf3493ca58b1a084f37e9b53e520 109 Gene3D G3DSA:3.30.460.10 2 103 4.0E-14 T 29-03-2018 THSYN_RS05590 2297bf3493ca58b1a084f37e9b53e520 109 Pfam PF01909 Nucleotidyltransferase domain 15 84 2.7E-8 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS12190 4625c4b8b4bbbc7d836bad13a86c59ef 316 SUPERFAMILY SSF51735 5 284 3.15E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS12190 4625c4b8b4bbbc7d836bad13a86c59ef 316 Gene3D G3DSA:3.40.50.720 1 146 3.9E-18 T 29-03-2018 THSYN_RS12190 4625c4b8b4bbbc7d836bad13a86c59ef 316 Pfam PF05368 NmrA-like family 7 251 4.8E-37 T 29-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 THSYN_RS28130 cc0b99e5548c419745780f3f0500f8cb 419 Pfam PF00482 Type II secretion system (T2SS), protein F 85 208 1.7E-29 T 29-03-2018 IPR018076 Type II secretion system F domain THSYN_RS28130 cc0b99e5548c419745780f3f0500f8cb 419 Pfam PF00482 Type II secretion system (T2SS), protein F 289 411 3.8E-34 T 29-03-2018 IPR018076 Type II secretion system F domain THSYN_RS28130 cc0b99e5548c419745780f3f0500f8cb 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 400 419 1.3E-17 T 29-03-2018 IPR003004 GspF/PilC family THSYN_RS28130 cc0b99e5548c419745780f3f0500f8cb 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 81 93 1.3E-17 T 29-03-2018 IPR003004 GspF/PilC family THSYN_RS28130 cc0b99e5548c419745780f3f0500f8cb 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 180 208 1.3E-17 T 29-03-2018 IPR003004 GspF/PilC family THSYN_RS28130 cc0b99e5548c419745780f3f0500f8cb 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 384 398 1.3E-17 T 29-03-2018 IPR003004 GspF/PilC family THSYN_RS31985 952951e98bab5605bf5accde3aa25f07 947 SUPERFAMILY SSF52540 353 375 6.48E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31985 952951e98bab5605bf5accde3aa25f07 947 SUPERFAMILY SSF52540 182 300 6.48E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31985 952951e98bab5605bf5accde3aa25f07 947 SUPERFAMILY SSF52540 42 115 6.48E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31985 952951e98bab5605bf5accde3aa25f07 947 Gene3D G3DSA:3.40.50.300 5 665 2.5E-30 T 29-03-2018 THSYN_RS31985 952951e98bab5605bf5accde3aa25f07 947 Pfam PF00350 Dynamin family 65 293 5.7E-20 T 29-03-2018 IPR022812 Dynamin superfamily THSYN_RS31985 952951e98bab5605bf5accde3aa25f07 947 Pfam PF16565 Phospholipase D-like domain at C-terminus of MIT 798 936 5.4E-22 T 29-03-2018 IPR032341 MIT, C-terminal phospholipase D-like domain THSYN_RS25970 b307265fe09008067b9f0b74dde28e71 185 PIRSF PIRSF000847 2 183 6.4E-42 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 THSYN_RS25970 b307265fe09008067b9f0b74dde28e71 185 Pfam PF01066 CDP-alcohol phosphatidyltransferase 6 69 1.9E-12 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THSYN_RS01115 09991bbeec86bcb3a904aea57d3d239b 582 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 9 572 6.0E-169 T 29-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 THSYN_RS01115 09991bbeec86bcb3a904aea57d3d239b 582 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 9 568 6.9E-258 T 29-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 THSYN_RS01115 09991bbeec86bcb3a904aea57d3d239b 582 PIRSF PIRSF000719 1 576 6.9E-240 T 29-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 THSYN_RS01115 09991bbeec86bcb3a904aea57d3d239b 582 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 1 572 44.735 T 29-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 THSYN_RS24755 901964dd8208790f253325f64016c48e 69 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 42 1.5E-9 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS24755 901964dd8208790f253325f64016c48e 69 SUPERFAMILY SSF143120 4 44 1.96E-9 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS24755 901964dd8208790f253325f64016c48e 69 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 45 3.3E-7 T 29-03-2018 THSYN_RS24755 901964dd8208790f253325f64016c48e 69 Gene3D G3DSA:3.40.1620.10 3 64 5.2E-13 T 29-03-2018 THSYN_RS16230 d3b73d34a5a6b070678aa2fa486c2dbb 122 Gene3D G3DSA:1.10.10.10 8 122 8.2E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS16230 d3b73d34a5a6b070678aa2fa486c2dbb 122 SUPERFAMILY SSF46785 39 104 2.42E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS11190 cf3929f14d0493fd78009060543d8031 272 Pfam PF04233 Phage Mu protein F like protein 55 176 1.2E-17 T 29-03-2018 IPR006528 Phage head morphogenesis domain THSYN_RS00700 9c8b586c29920ea12b2285a97dd8e40c 384 Pfam PF13635 Domain of unknown function (DUF4143) 176 332 1.3E-22 T 29-03-2018 IPR025420 Domain of unknown function DUF4143 THSYN_RS00700 9c8b586c29920ea12b2285a97dd8e40c 384 Gene3D G3DSA:3.40.50.300 3 124 3.9E-9 T 29-03-2018 THSYN_RS00700 9c8b586c29920ea12b2285a97dd8e40c 384 SUPERFAMILY SSF52540 3 179 6.74E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS00700 9c8b586c29920ea12b2285a97dd8e40c 384 Gene3D G3DSA:1.10.10.10 164 248 0.034 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS00700 9c8b586c29920ea12b2285a97dd8e40c 384 Pfam PF13173 AAA domain 18 136 7.4E-22 T 29-03-2018 THSYN_RS32995 088f501ba3ba15b918a3d879903bcc82 330 TIGRFAM TIGR03866 PQQ_ABC_repeats: PQQ-dependent catabolism-associated beta-propeller protein 26 330 6.4E-149 T 29-03-2018 IPR022456 PQQ-dependent catabolism-associated beta-propeller protein THSYN_RS32995 088f501ba3ba15b918a3d879903bcc82 330 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 112 150 1.9E-11 T 29-03-2018 IPR011964 YVTN beta-propeller repeat THSYN_RS32995 088f501ba3ba15b918a3d879903bcc82 330 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 288 328 8.9E-8 T 29-03-2018 IPR011964 YVTN beta-propeller repeat THSYN_RS32995 088f501ba3ba15b918a3d879903bcc82 330 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 32 69 1.6E-8 T 29-03-2018 IPR011964 YVTN beta-propeller repeat THSYN_RS32995 088f501ba3ba15b918a3d879903bcc82 330 Gene3D G3DSA:2.130.10.10 149 268 3.1E-25 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS32995 088f501ba3ba15b918a3d879903bcc82 330 Gene3D G3DSA:2.130.10.10 23 148 4.0E-26 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS32995 088f501ba3ba15b918a3d879903bcc82 330 Pfam PF02239 Cytochrome D1 heme domain 77 176 2.6E-7 T 29-03-2018 THSYN_RS32995 088f501ba3ba15b918a3d879903bcc82 330 SUPERFAMILY SSF50974 10 330 3.01E-80 T 29-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 THSYN_RS32995 088f501ba3ba15b918a3d879903bcc82 330 Gene3D G3DSA:2.130.10.10 269 330 2.0E-8 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS00275 c6d2daeb8a602a5f4609b123fa0e481a 390 SUPERFAMILY SSF50952 28 387 1.96E-49 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 THSYN_RS00275 c6d2daeb8a602a5f4609b123fa0e481a 390 Gene3D G3DSA:2.120.10.30 27 288 3.2E-55 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS00275 c6d2daeb8a602a5f4609b123fa0e481a 390 Gene3D G3DSA:2.120.10.30 289 380 2.1E-13 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like THSYN_RS00275 c6d2daeb8a602a5f4609b123fa0e481a 390 Pfam PF07995 Glucose / Sorbosone dehydrogenase 48 382 3.5E-123 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase THSYN_RS28085 1392b5b1a6885f041da3d9dbf97744c4 85 Pfam PF13937 Domain of unknown function (DUF4212) 6 82 5.2E-36 T 29-03-2018 IPR019886 Sodium symporter small subunit, predicted THSYN_RS28085 1392b5b1a6885f041da3d9dbf97744c4 85 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 8 84 2.2E-36 T 29-03-2018 IPR019886 Sodium symporter small subunit, predicted THSYN_RS32945 333d03227073ce3e663de6f323f63950 90 SUPERFAMILY SSF56300 8 69 3.16E-9 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS32945 333d03227073ce3e663de6f323f63950 90 Gene3D G3DSA:3.60.21.10 1 73 1.1E-10 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS30960 2fb0e124062b49f739b3d1c79362a9ba 311 Gene3D G3DSA:3.40.1800.10 196 288 5.4E-10 T 29-03-2018 THSYN_RS30960 2fb0e124062b49f739b3d1c79362a9ba 311 Pfam PF01844 HNH endonuclease 218 274 9.2E-7 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 THSYN_RS19615 53f88236065f942f6414021d941286d6 370 Pfam PF00535 Glycosyl transferase family 2 8 172 2.0E-31 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS19615 53f88236065f942f6414021d941286d6 370 SUPERFAMILY SSF53448 3 174 7.96E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS19615 53f88236065f942f6414021d941286d6 370 Pfam PF04138 GtrA-like protein 244 364 3.3E-17 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 THSYN_RS19615 53f88236065f942f6414021d941286d6 370 Gene3D G3DSA:3.90.550.10 1 243 2.8E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS14830 42ab7c820f51757a2837e84ba1b5a35b 408 Pfam PF01420 Type I restriction modification DNA specificity domain 221 385 2.5E-10 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS14830 42ab7c820f51757a2837e84ba1b5a35b 408 Pfam PF01420 Type I restriction modification DNA specificity domain 96 190 1.6E-10 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THSYN_RS14830 42ab7c820f51757a2837e84ba1b5a35b 408 SUPERFAMILY SSF116734 208 400 6.21E-30 T 29-03-2018 THSYN_RS14830 42ab7c820f51757a2837e84ba1b5a35b 408 SUPERFAMILY SSF116734 6 202 9.97E-32 T 29-03-2018 THSYN_RS14830 42ab7c820f51757a2837e84ba1b5a35b 408 Gene3D G3DSA:3.90.220.20 8 183 3.2E-19 T 29-03-2018 THSYN_RS14830 42ab7c820f51757a2837e84ba1b5a35b 408 Gene3D G3DSA:3.90.220.20 184 386 3.4E-28 T 29-03-2018 THSYN_RS32925 ad023fac0bcae56516a131982433a219 455 Pfam PF14067 LssY C-terminus 259 436 2.1E-49 T 29-03-2018 IPR025902 LssY-like C-terminal domain THSYN_RS16345 8ba161f28882b4b493b46d8625ee7b6a 60 Gene3D G3DSA:1.10.150.320 1 60 1.7E-17 T 29-03-2018 THSYN_RS16345 8ba161f28882b4b493b46d8625ee7b6a 60 Pfam PF12836 Helix-hairpin-helix motif 2 56 2.3E-16 T 29-03-2018 THSYN_RS16345 8ba161f28882b4b493b46d8625ee7b6a 60 SMART SM00278 36 55 1.5 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THSYN_RS16345 8ba161f28882b4b493b46d8625ee7b6a 60 SMART SM00278 10 29 0.04 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THSYN_RS16345 8ba161f28882b4b493b46d8625ee7b6a 60 SUPERFAMILY SSF81585 2 58 4.12E-19 T 29-03-2018 THSYN_RS25830 82338279f342e7a50037f371d025385d 321 Pfam PF13661 2OG-Fe(II) oxygenase superfamily 90 174 1.4E-7 T 29-03-2018 THSYN_RS25830 82338279f342e7a50037f371d025385d 321 Gene3D G3DSA:2.60.120.620 3 183 2.8E-8 T 29-03-2018 THSYN_RS03620 f219d30836ca94c4e27df9e1d799bda7 524 Gene3D G3DSA:3.50.50.60 14 428 9.0E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03620 f219d30836ca94c4e27df9e1d799bda7 524 SUPERFAMILY SSF51905 18 316 1.87E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS03620 f219d30836ca94c4e27df9e1d799bda7 524 Pfam PF13450 NAD(P)-binding Rossmann-like domain 24 92 4.3E-12 T 29-03-2018 THSYN_RS26725 23a38fb76c41860692d53a9a442459f0 454 SUPERFAMILY SSF53474 295 444 4.47E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS26725 23a38fb76c41860692d53a9a442459f0 454 SUPERFAMILY SSF53474 39 95 4.81E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS26725 23a38fb76c41860692d53a9a442459f0 454 SUPERFAMILY SSF53474 126 210 4.81E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS26725 23a38fb76c41860692d53a9a442459f0 454 Gene3D G3DSA:3.40.50.1820 15 211 3.1E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS27540 1d77893b09f9be96c08c2bd0bec86e7a 105 Gene3D G3DSA:3.30.460.10 1 105 7.4E-16 T 29-03-2018 THSYN_RS27540 1d77893b09f9be96c08c2bd0bec86e7a 105 Pfam PF01909 Nucleotidyltransferase domain 9 55 4.4E-8 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS27540 1d77893b09f9be96c08c2bd0bec86e7a 105 SUPERFAMILY SSF81301 4 73 3.49E-14 T 29-03-2018 THSYN_RS30605 a0f7f3e1f258fe35127a43e192fa82ac 602 Pfam PF00860 Permease family 45 427 3.8E-33 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THSYN_RS31725 ce206975fbfc27c3091146207612fce0 285 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 31 255 2.8E-95 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related THSYN_RS31725 ce206975fbfc27c3091146207612fce0 285 PIRSF PIRSF028756 1 285 4.4E-114 T 29-03-2018 IPR016898 Polyphosphate kinase 2 THSYN_RS31725 ce206975fbfc27c3091146207612fce0 285 SUPERFAMILY SSF52540 62 251 2.21E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31725 ce206975fbfc27c3091146207612fce0 285 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 30 256 4.2E-104 T 29-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 THSYN_RS31725 ce206975fbfc27c3091146207612fce0 285 Gene3D G3DSA:3.40.50.300 2 274 2.8E-95 T 29-03-2018 THSYN_RS31250 a0fa0317bf4aad5f89b027f7b874467e 81 Gene3D G3DSA:4.10.220.20 21 63 8.3E-16 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31250 a0fa0317bf4aad5f89b027f7b874467e 81 SUPERFAMILY SSF56918 17 63 3.14E-8 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS22220 491b4807009c3a1aa137b4bd683fbf32 486 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 1 481 56.404 T 29-03-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 THSYN_RS22220 491b4807009c3a1aa137b4bd683fbf32 486 Gene3D G3DSA:3.90.1150.10 338 466 9.6E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 THSYN_RS22220 491b4807009c3a1aa137b4bd683fbf32 486 Pfam PF02347 Glycine cleavage system P-protein 41 369 7.3E-11 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 THSYN_RS22220 491b4807009c3a1aa137b4bd683fbf32 486 Gene3D G3DSA:3.40.640.10 74 337 4.5E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THSYN_RS22220 491b4807009c3a1aa137b4bd683fbf32 486 SUPERFAMILY SSF53383 3 480 6.6E-116 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase THSYN_RS21105 f47373f5e69f11ee6903c9d1934e5943 98 Pfam PF04754 Putative transposase, YhgA-like 6 92 1.8E-22 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS21685 dac78408706a8c591cc3f1ee349b4456 97 Gene3D G3DSA:1.10.1220.10 13 55 1.9E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS21685 dac78408706a8c591cc3f1ee349b4456 97 Pfam PF01402 Ribbon-helix-helix protein, copG family 17 52 3.0E-4 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 THSYN_RS17500 3ea1f539a044ed4648640c85639d4233 326 PRINTS PR01217 Proline rich extensin signature 135 147 2.5E-9 T 29-03-2018 THSYN_RS17500 3ea1f539a044ed4648640c85639d4233 326 PRINTS PR01217 Proline rich extensin signature 197 214 2.5E-9 T 29-03-2018 THSYN_RS17500 3ea1f539a044ed4648640c85639d4233 326 PRINTS PR01217 Proline rich extensin signature 176 192 2.5E-9 T 29-03-2018 THSYN_RS17500 3ea1f539a044ed4648640c85639d4233 326 PRINTS PR01217 Proline rich extensin signature 148 169 2.5E-9 T 29-03-2018 THSYN_RS08610 f267a8a83a705b6f0a1ec6e1d60f2afc 142 Gene3D G3DSA:3.40.50.1010 1 136 6.0E-17 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS08610 f267a8a83a705b6f0a1ec6e1d60f2afc 142 SUPERFAMILY SSF88723 1 135 4.49E-16 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS08610 f267a8a83a705b6f0a1ec6e1d60f2afc 142 Pfam PF01850 PIN domain 6 123 6.9E-9 T 29-03-2018 IPR002716 PIN domain THSYN_RS28735 6ac296954263cc27ae1a964c0063231f 90 SUPERFAMILY SSF47598 7 46 4.11E-5 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS28735 6ac296954263cc27ae1a964c0063231f 90 Gene3D G3DSA:1.10.1220.10 9 46 1.2E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS28735 6ac296954263cc27ae1a964c0063231f 90 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 9 75 8.2E-18 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS28735 6ac296954263cc27ae1a964c0063231f 90 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 5 67 3.2E-12 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS29715 1996a9e1a38b73af197b1d6888879523 717 Pfam PF12288 Carboxysome shell peptide mid-region 84 515 3.2E-164 T 29-03-2018 IPR020990 Carboxysome shell protein THSYN_RS16900 d6faa967d940e193e76ca0b001706986 128 Gene3D G3DSA:3.10.180.10 1 128 4.2E-38 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THSYN_RS16900 d6faa967d940e193e76ca0b001706986 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 123 3.8E-24 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THSYN_RS16900 d6faa967d940e193e76ca0b001706986 128 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 127 2.8E-62 T 29-03-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 THSYN_RS16900 d6faa967d940e193e76ca0b001706986 128 ProSitePatterns PS00935 Glyoxalase I signature 2. 69 81 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 THSYN_RS16900 d6faa967d940e193e76ca0b001706986 128 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 THSYN_RS16900 d6faa967d940e193e76ca0b001706986 128 SUPERFAMILY SSF54593 1 127 2.69E-37 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THSYN_RS23270 78e8cafddee608786afa29681f4e8a2c 98 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 74 2.6E-15 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain THSYN_RS23270 78e8cafddee608786afa29681f4e8a2c 98 Gene3D G3DSA:3.30.70.100 1 89 8.8E-25 T 29-03-2018 THSYN_RS23270 78e8cafddee608786afa29681f4e8a2c 98 SUPERFAMILY SSF54909 1 94 9.06E-27 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel THSYN_RS32725 6e687e4acad9c17a723d023ce415d993 177 SUPERFAMILY SSF55724 25 157 4.97E-13 T 29-03-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich Reactome: R-HSA-5576892 THSYN_RS32725 6e687e4acad9c17a723d023ce415d993 177 Pfam PF08786 DcrB 26 151 1.3E-11 T 29-03-2018 IPR014894 Protein DcrB THSYN_RS32725 6e687e4acad9c17a723d023ce415d993 177 Gene3D G3DSA:3.40.1000.10 14 162 5.4E-17 T 29-03-2018 THSYN_RS22140 9054d024ce80f16b52c85960402f8975 160 Pfam PF11159 Protein of unknown function (DUF2939) 9 97 2.1E-14 T 29-03-2018 IPR021330 Protein of unknown function DUF2939 THSYN_RS27775 c711f485e624accc1303bdb04e03fe92 246 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS27775 c711f485e624accc1303bdb04e03fe92 246 SMART SM00382 30 218 1.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS27775 c711f485e624accc1303bdb04e03fe92 246 Gene3D G3DSA:3.40.50.300 2 227 1.6E-55 T 29-03-2018 THSYN_RS27775 c711f485e624accc1303bdb04e03fe92 246 Pfam PF00005 ABC transporter 21 171 9.0E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS27775 c711f485e624accc1303bdb04e03fe92 246 SUPERFAMILY SSF52540 3 222 2.61E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03560 930815c4157ca44177630423da4a7d25 476 SUPERFAMILY SSF53623 101 319 1.05E-72 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS03560 930815c4157ca44177630423da4a7d25 476 Pfam PF08245 Mur ligase middle domain 120 301 1.0E-28 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS03560 930815c4157ca44177630423da4a7d25 476 SUPERFAMILY SSF53244 320 468 5.31E-43 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THSYN_RS03560 930815c4157ca44177630423da4a7d25 476 SUPERFAMILY SSF51984 16 102 7.46E-27 T 29-03-2018 THSYN_RS03560 930815c4157ca44177630423da4a7d25 476 Pfam PF02875 Mur ligase family, glutamate ligase domain 334 411 9.4E-20 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THSYN_RS03560 930815c4157ca44177630423da4a7d25 476 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 18 466 1.2E-166 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03560 930815c4157ca44177630423da4a7d25 476 Pfam PF01225 Mur ligase family, catalytic domain 18 116 6.8E-26 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 THSYN_RS03560 930815c4157ca44177630423da4a7d25 476 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 15 473 43.369 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THSYN_RS03560 930815c4157ca44177630423da4a7d25 476 Gene3D G3DSA:3.40.50.720 4 103 2.8E-19 T 29-03-2018 THSYN_RS03560 930815c4157ca44177630423da4a7d25 476 Gene3D G3DSA:3.90.190.20 322 473 2.4E-33 T 29-03-2018 THSYN_RS03560 930815c4157ca44177630423da4a7d25 476 Gene3D G3DSA:3.40.1190.10 104 321 3.2E-54 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 THSYN_RS31030 ef6aaf2ee32af50892a665d4e1eec789 166 Pfam PF13527 Acetyltransferase (GNAT) domain 3 128 1.2E-10 T 29-03-2018 THSYN_RS31030 ef6aaf2ee32af50892a665d4e1eec789 166 Gene3D G3DSA:3.40.630.30 1 155 1.0E-23 T 29-03-2018 THSYN_RS31030 ef6aaf2ee32af50892a665d4e1eec789 166 SUPERFAMILY SSF55729 2 161 9.09E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS02850 3dffc4c6b55b87cecb8b4e2fd7161dcc 603 Pfam PF13203 Putative metallopeptidase domain 216 454 7.0E-20 T 29-03-2018 IPR025154 Putative metallopeptidase domain THSYN_RS20200 704541864c746dc352944ed0a4dbe9cf 160 SUPERFAMILY SSF88723 22 128 2.68E-9 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS20200 704541864c746dc352944ed0a4dbe9cf 160 Gene3D G3DSA:3.40.50.1010 2 145 5.1E-15 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS20200 704541864c746dc352944ed0a4dbe9cf 160 Pfam PF01850 PIN domain 31 120 1.1E-5 T 29-03-2018 IPR002716 PIN domain THSYN_RS23495 82aa2aae1e7a6ca3fa72d478a7e09906 382 SUPERFAMILY SSF52540 119 339 2.99E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23495 82aa2aae1e7a6ca3fa72d478a7e09906 382 SUPERFAMILY SSF52540 1 84 2.99E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23495 82aa2aae1e7a6ca3fa72d478a7e09906 382 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 25 332 1.5E-15 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS23495 82aa2aae1e7a6ca3fa72d478a7e09906 382 Gene3D G3DSA:3.40.50.300 1 359 1.7E-15 T 29-03-2018 THSYN_RS20375 86dbd347c3ad2e6e9b02f65e40745128 130 Gene3D G3DSA:1.20.5.1000 26 84 1.0E-4 T 29-03-2018 THSYN_RS20375 86dbd347c3ad2e6e9b02f65e40745128 130 Pfam PF04977 Septum formation initiator 11 89 3.9E-24 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 THSYN_RS20375 86dbd347c3ad2e6e9b02f65e40745128 130 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 30.79 T 29-03-2018 IPR023081 Cell division protein FtsB THSYN_RS30795 a59a57d261d18ed151ac78c51139ee7f 904 Pfam PF08665 PglZ domain 485 658 4.2E-5 T 29-03-2018 IPR013973 PglZ domain THSYN_RS30795 a59a57d261d18ed151ac78c51139ee7f 904 SUPERFAMILY SSF53649 483 610 5.23E-6 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS30795 a59a57d261d18ed151ac78c51139ee7f 904 SUPERFAMILY SSF53649 641 736 5.23E-6 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS14245 c7fdffcd11a380f2b0dd31b0fa362154 207 Pfam PF06250 Protein of unknown function (DUF1016) 4 187 9.6E-60 T 29-03-2018 IPR009362 Protein of unknown function DUF1016 THSYN_RS13840 98eaf5c4ee2467fccc4eb33bd48315a6 73 Gene3D G3DSA:3.30.920.30 4 73 9.0E-12 T 29-03-2018 THSYN_RS13840 98eaf5c4ee2467fccc4eb33bd48315a6 73 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 11 65 7.0E-9 T 29-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 THSYN_RS13840 98eaf5c4ee2467fccc4eb33bd48315a6 73 SUPERFAMILY SSF54786 7 70 6.67E-10 T 29-03-2018 THSYN_RS17945 368fcc5e956094aee0a963c6e0451ef4 257 Pfam PF06167 Glucose-regulated metallo-peptidase M90 7 248 9.5E-87 T 29-03-2018 IPR010384 MtfA family THSYN_RS17945 368fcc5e956094aee0a963c6e0451ef4 257 Gene3D G3DSA:3.40.390.10 52 250 4.4E-25 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 THSYN_RS17945 368fcc5e956094aee0a963c6e0451ef4 257 SUPERFAMILY SSF55486 40 250 2.69E-43 T 29-03-2018 THSYN_RS18840 29b014acea4b4f7dfc2ad412ac58f00d 256 Gene3D G3DSA:1.20.5.1230 24 203 4.7E-5 T 29-03-2018 THSYN_RS19325 5b3906949d398e939aa5ad7857be65ba 228 SUPERFAMILY SSF46785 142 215 3.52E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19325 5b3906949d398e939aa5ad7857be65ba 228 Pfam PF13545 Crp-like helix-turn-helix domain 145 210 4.2E-14 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THSYN_RS19325 5b3906949d398e939aa5ad7857be65ba 228 SUPERFAMILY SSF51206 4 123 6.77E-9 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like THSYN_RS19325 5b3906949d398e939aa5ad7857be65ba 228 Gene3D G3DSA:2.60.120.10 4 130 2.0E-5 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS19325 5b3906949d398e939aa5ad7857be65ba 228 Gene3D G3DSA:1.10.10.10 140 227 1.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS02665 5ce2b308c04b420e6cf6e33870dab9d4 196 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 181 2.2E-32 T 29-03-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA THSYN_RS02665 5ce2b308c04b420e6cf6e33870dab9d4 196 Gene3D G3DSA:3.40.50.1820 1 196 2.8E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS02665 5ce2b308c04b420e6cf6e33870dab9d4 196 SUPERFAMILY SSF53474 2 185 9.8E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS09050 764bebb443cf4e69976c792686a0193f 181 Pfam PF13511 Domain of unknown function (DUF4124) 31 75 3.5E-5 T 29-03-2018 IPR025392 Domain of unknown function DUF4124 THSYN_RS09050 764bebb443cf4e69976c792686a0193f 181 Gene3D G3DSA:1.20.5.320 92 173 5.7E-4 T 29-03-2018 THSYN_RS16665 dc5485ad408740d6353c4164af4cdd94 133 SUPERFAMILY SSF88723 2 128 1.57E-19 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS16665 dc5485ad408740d6353c4164af4cdd94 133 Gene3D G3DSA:3.40.50.1010 1 127 1.2E-16 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS16665 dc5485ad408740d6353c4164af4cdd94 133 Pfam PF01850 PIN domain 2 124 6.1E-15 T 29-03-2018 IPR002716 PIN domain THSYN_RS16665 dc5485ad408740d6353c4164af4cdd94 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 131 12.108 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS24905 8db262c22bc7bd2c89dd03dd439e185a 312 SUPERFAMILY SSF56112 12 52 1.48E-48 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS24905 8db262c22bc7bd2c89dd03dd439e185a 312 SUPERFAMILY SSF56112 79 288 1.48E-48 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS24905 8db262c22bc7bd2c89dd03dd439e185a 312 Pfam PF00069 Protein kinase domain 18 243 2.0E-28 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS24905 8db262c22bc7bd2c89dd03dd439e185a 312 Gene3D G3DSA:3.30.200.20 13 102 3.8E-17 T 29-03-2018 THSYN_RS24905 8db262c22bc7bd2c89dd03dd439e185a 312 Gene3D G3DSA:1.10.510.10 103 306 9.7E-30 T 29-03-2018 THSYN_RS24905 8db262c22bc7bd2c89dd03dd439e185a 312 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 24 53 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 THSYN_RS24905 8db262c22bc7bd2c89dd03dd439e185a 312 SMART SM00220 18 292 8.9E-15 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THSYN_RS28570 43e61e2de8578c55723fde5a084d9c98 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 193 206 9.9E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS28570 43e61e2de8578c55723fde5a084d9c98 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 163 9.9E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS28570 43e61e2de8578c55723fde5a084d9c98 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 9.9E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS28570 43e61e2de8578c55723fde5a084d9c98 245 SUPERFAMILY SSF56784 6 232 1.99E-39 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS28570 43e61e2de8578c55723fde5a084d9c98 245 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 97 204 1.0E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS28570 43e61e2de8578c55723fde5a084d9c98 245 Pfam PF13419 Haloacid dehalogenase-like hydrolase 105 204 3.6E-12 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS28570 43e61e2de8578c55723fde5a084d9c98 245 Gene3D G3DSA:3.40.50.1000 93 235 2.5E-24 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS28570 43e61e2de8578c55723fde5a084d9c98 245 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 106 198 7.9E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THSYN_RS24495 736edf827c665782ba413bfd8f79df02 322 SUPERFAMILY SSF48576 10 321 1.34E-98 T 29-03-2018 IPR008949 Isoprenoid synthase domain THSYN_RS24495 736edf827c665782ba413bfd8f79df02 322 Gene3D G3DSA:1.10.600.10 3 322 3.0E-100 T 29-03-2018 IPR008949 Isoprenoid synthase domain THSYN_RS24495 736edf827c665782ba413bfd8f79df02 322 Pfam PF00348 Polyprenyl synthetase 31 270 1.3E-75 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 THSYN_RS23625 104f512acceea145052fca80295416fb 87 Gene3D G3DSA:3.40.50.1110 1 65 3.6E-12 T 29-03-2018 THSYN_RS07140 795ddacdaccbd6b47ff85682e08c2fda 227 Pfam PF13487 HD domain 76 158 3.4E-14 T 29-03-2018 THSYN_RS07140 795ddacdaccbd6b47ff85682e08c2fda 227 Gene3D G3DSA:1.10.3210.10 49 217 3.6E-40 T 29-03-2018 THSYN_RS07140 795ddacdaccbd6b47ff85682e08c2fda 227 SUPERFAMILY SSF109604 52 99 8.48E-28 T 29-03-2018 THSYN_RS07140 795ddacdaccbd6b47ff85682e08c2fda 227 SUPERFAMILY SSF109604 132 206 8.48E-28 T 29-03-2018 THSYN_RS07140 795ddacdaccbd6b47ff85682e08c2fda 227 Gene3D G3DSA:3.40.50.2300 2 48 0.0024 T 29-03-2018 THSYN_RS24275 ed9a6735f6e8944e327aad848bb3a5cc 91 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 61 85 7.7E-6 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS24275 ed9a6735f6e8944e327aad848bb3a5cc 91 Pfam PF07589 PEP-CTERM motif 60 83 3.0E-5 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS24275 ed9a6735f6e8944e327aad848bb3a5cc 91 TIGRFAM TIGR03370 VPLPA-CTERM: VPLPA-CTERM protein sorting domain 61 85 1.5E-7 T 29-03-2018 IPR022472 VPLPA-CTERM protein sorting domain THSYN_RS00145 74dad37fa8c062de295ef22408b36e05 345 Pfam PF00953 Glycosyl transferase family 4 79 233 4.8E-28 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 THSYN_RS19015 01834f3dd456816a7687c762ef13310d 348 PIRSF PIRSF000294 3 348 7.5E-144 T 29-03-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 THSYN_RS19015 01834f3dd456816a7687c762ef13310d 348 SUPERFAMILY SSF46626 190 345 4.48E-39 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS19015 01834f3dd456816a7687c762ef13310d 348 Pfam PF03150 Di-haem cytochrome c peroxidase 54 203 1.2E-50 T 29-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 THSYN_RS19015 01834f3dd456816a7687c762ef13310d 348 Gene3D G3DSA:1.10.760.10 208 329 2.1E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS19015 01834f3dd456816a7687c762ef13310d 348 Gene3D G3DSA:1.10.760.10 43 207 1.3E-45 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS19015 01834f3dd456816a7687c762ef13310d 348 SUPERFAMILY SSF46626 44 191 6.86E-51 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS19015 01834f3dd456816a7687c762ef13310d 348 Pfam PF00034 Cytochrome c 211 314 1.5E-7 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS11080 538720e821f3970c026405500fe96fce 307 Pfam PF13460 NAD(P)H-binding 7 209 3.1E-23 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS11080 538720e821f3970c026405500fe96fce 307 Gene3D G3DSA:3.40.50.720 1 306 1.3E-36 T 29-03-2018 THSYN_RS11080 538720e821f3970c026405500fe96fce 307 SUPERFAMILY SSF51735 1 291 3.57E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS15370 90620bb8caa4407342844a8094a5a50d 106 SUPERFAMILY SSF143602 3 104 3.66E-20 T 29-03-2018 THSYN_RS15370 90620bb8caa4407342844a8094a5a50d 106 Pfam PF08960 Domain of unknown function (DUF1874) 3 98 1.0E-24 T 29-03-2018 IPR015055 Acidianus two-tailed virus, Orf117 THSYN_RS29770 c4608b9a76fd3ada7eb78507bd62081a 207 SUPERFAMILY SSF55811 31 181 3.66E-20 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 THSYN_RS29770 c4608b9a76fd3ada7eb78507bd62081a 207 Gene3D G3DSA:3.90.79.10 27 182 1.8E-22 T 29-03-2018 THSYN_RS29770 c4608b9a76fd3ada7eb78507bd62081a 207 Pfam PF00293 NUDIX domain 51 164 9.8E-12 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THSYN_RS12150 3e0414d90824b90c4bd351eade65c3f1 463 Pfam PF01522 Polysaccharide deacetylase 219 361 3.6E-16 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 THSYN_RS12150 3e0414d90824b90c4bd351eade65c3f1 463 SUPERFAMILY SSF88713 219 433 2.89E-38 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS12150 3e0414d90824b90c4bd351eade65c3f1 463 Gene3D G3DSA:3.20.20.370 212 439 2.9E-37 T 29-03-2018 THSYN_RS20045 3ff982b622e7cef9b2e7440f82f24c63 77 Gene3D G3DSA:3.50.50.60 4 76 2.0E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS16145 f3efdca23c1150a3cd352901feb975c9 723 Gene3D G3DSA:1.10.150.200 469 532 4.7E-7 T 29-03-2018 THSYN_RS16145 f3efdca23c1150a3cd352901feb975c9 723 Gene3D G3DSA:1.10.150.200 293 342 1.1E-4 T 29-03-2018 THSYN_RS16145 f3efdca23c1150a3cd352901feb975c9 723 Gene3D G3DSA:1.20.1250.10 343 397 1.1E-8 T 29-03-2018 THSYN_RS16145 f3efdca23c1150a3cd352901feb975c9 723 SUPERFAMILY SSF48452 246 403 2.73E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16145 f3efdca23c1150a3cd352901feb975c9 723 Pfam PF13374 Tetratricopeptide repeat 464 502 0.009 T 29-03-2018 THSYN_RS16145 f3efdca23c1150a3cd352901feb975c9 723 SUPERFAMILY SSF48452 322 402 6.03E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16145 f3efdca23c1150a3cd352901feb975c9 723 SUPERFAMILY SSF48452 439 595 6.03E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16145 f3efdca23c1150a3cd352901feb975c9 723 Gene3D G3DSA:1.25.40.10 398 468 1.3E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS16145 f3efdca23c1150a3cd352901feb975c9 723 Gene3D G3DSA:1.25.40.10 533 644 2.4E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS00530 f78cc5e6f43a14e6bb0e0431fc42c165 98 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 93 4.0E-17 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS00530 f78cc5e6f43a14e6bb0e0431fc42c165 98 PIRSF PIRSF029218 2 98 2.7E-28 T 29-03-2018 IPR028344 Toxin-antitoxin system, toxin component ParE1/4 THSYN_RS08895 ab114aafed4f8d9ab2a0e2fdf629c0f6 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 127 1.7E-12 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THSYN_RS08895 ab114aafed4f8d9ab2a0e2fdf629c0f6 129 SUPERFAMILY SSF54593 1 128 1.75E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THSYN_RS08895 ab114aafed4f8d9ab2a0e2fdf629c0f6 129 Gene3D G3DSA:3.10.180.10 1 129 1.5E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THSYN_RS26965 484c1fea392bbfcf74617953cae73a4f 209 Pfam PF04205 FMN-binding domain 97 185 7.2E-18 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 THSYN_RS26965 484c1fea392bbfcf74617953cae73a4f 209 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 10 190 8.4E-52 T 29-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 THSYN_RS26965 484c1fea392bbfcf74617953cae73a4f 209 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 3 191 24.97 T 29-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 THSYN_RS26965 484c1fea392bbfcf74617953cae73a4f 209 PIRSF PIRSF006091 1 203 3.4E-72 T 29-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 THSYN_RS26965 484c1fea392bbfcf74617953cae73a4f 209 SMART SM00900 97 189 2.3E-34 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 THSYN_RS16240 2b67dfb57d3dce9684c585677ef95c65 72 SUPERFAMILY SSF46689 4 70 8.6E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS16240 2b67dfb57d3dce9684c585677ef95c65 72 Gene3D G3DSA:1.10.10.10 10 71 1.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS16240 2b67dfb57d3dce9684c585677ef95c65 72 Pfam PF04255 Protein of unknown function (DUF433) 10 64 8.1E-15 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS06590 8ace48216f9a3db5c9942062de2e8f5c 120 Gene3D G3DSA:3.30.530.20 34 116 0.39 T 29-03-2018 IPR023393 START-like domain THSYN_RS25090 aa8454230d963253fc8a6a7d649e1a1d 238 Gene3D G3DSA:3.40.50.150 7 187 2.0E-21 T 29-03-2018 THSYN_RS25090 aa8454230d963253fc8a6a7d649e1a1d 238 Pfam PF13489 Methyltransferase domain 43 182 5.6E-13 T 29-03-2018 THSYN_RS25090 aa8454230d963253fc8a6a7d649e1a1d 238 SUPERFAMILY SSF53335 31 191 5.43E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS21725 7c90152a7aa7e9054cf0c91c34be8fbc 457 Gene3D G3DSA:1.20.1600.10 24 438 4.5E-68 T 29-03-2018 THSYN_RS21725 7c90152a7aa7e9054cf0c91c34be8fbc 457 SUPERFAMILY SSF56954 3 434 6.41E-81 T 29-03-2018 THSYN_RS21725 7c90152a7aa7e9054cf0c91c34be8fbc 457 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 26 447 6.0E-95 T 29-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 THSYN_RS21725 7c90152a7aa7e9054cf0c91c34be8fbc 457 Pfam PF02321 Outer membrane efflux protein 253 431 6.1E-33 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THSYN_RS21725 7c90152a7aa7e9054cf0c91c34be8fbc 457 Pfam PF02321 Outer membrane efflux protein 32 225 9.5E-21 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THSYN_RS01900 7be02ccc4c755aa21b7496ae930073bd 404 SUPERFAMILY SSF56601 55 382 2.44E-61 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like THSYN_RS01900 7be02ccc4c755aa21b7496ae930073bd 404 Gene3D G3DSA:3.40.710.10 51 388 7.2E-64 T 29-03-2018 THSYN_RS01900 7be02ccc4c755aa21b7496ae930073bd 404 Pfam PF00144 Beta-lactamase 59 377 5.1E-46 T 29-03-2018 IPR001466 Beta-lactamase-related THSYN_RS06880 9645284b7862285b3ae8ccf1224ebff8 590 Pfam PF02026 RyR domain 361 423 1.3E-9 T 29-03-2018 IPR003032 Ryanodine receptor Ryr Reactome: R-HSA-2672351|Reactome: R-HSA-5578775 THSYN_RS20030 f59b1531bca359bcb6f8137f5f0981d1 188 Pfam PF00293 NUDIX domain 43 150 5.2E-20 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THSYN_RS20030 f59b1531bca359bcb6f8137f5f0981d1 188 PRINTS PR00502 NUDIX hydrolase family signature 84 99 9.9E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THSYN_RS20030 f59b1531bca359bcb6f8137f5f0981d1 188 PRINTS PR00502 NUDIX hydrolase family signature 70 84 9.9E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THSYN_RS20030 f59b1531bca359bcb6f8137f5f0981d1 188 Gene3D G3DSA:3.90.79.10 1 174 3.2E-40 T 29-03-2018 THSYN_RS20030 f59b1531bca359bcb6f8137f5f0981d1 188 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THSYN_RS20030 f59b1531bca359bcb6f8137f5f0981d1 188 SUPERFAMILY SSF55811 6 170 9.07E-47 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 THSYN_RS32935 c40e3dd2b0b230db369062258da793ff 200 Pfam PF10646 Sporulation and spore germination 51 174 1.5E-10 T 29-03-2018 IPR019606 GerMN domain THSYN_RS13750 1de3db80b18178e57a8be4ac301ef6fc 305 Gene3D G3DSA:3.40.50.10140 2 156 1.3E-7 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THSYN_RS13750 1de3db80b18178e57a8be4ac301ef6fc 305 Pfam PF08357 SEFIR domain 4 135 4.5E-6 T 29-03-2018 IPR013568 SEFIR domain THSYN_RS31720 ff35e3d0d96d84ce1e84a9a2bd43ebd6 405 Pfam PF01734 Patatin-like phospholipase 86 269 3.4E-15 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 THSYN_RS31720 ff35e3d0d96d84ce1e84a9a2bd43ebd6 405 Gene3D G3DSA:3.40.1090.10 70 279 2.0E-21 T 29-03-2018 THSYN_RS31720 ff35e3d0d96d84ce1e84a9a2bd43ebd6 405 SUPERFAMILY SSF52151 82 389 3.4E-27 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS30080 58edc6f41215bc57df97a9548b557299 171 Pfam PF11848 Domain of unknown function (DUF3368) 119 164 9.6E-12 T 29-03-2018 IPR021799 Protein of unknown function DUF3368 THSYN_RS22345 f909a97ed072b480cc0977ba87ba2307 73 TIGRFAM TIGR02574 stabl_TIGR02574: putative addiction module component, TIGR02574 family 10 68 7.0E-12 T 29-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THSYN_RS22345 f909a97ed072b480cc0977ba87ba2307 73 Pfam PF09720 Putative addiction module component 12 64 4.8E-10 T 29-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THSYN_RS08680 32e90e77cee323c104034655a7d6d7aa 126 SUPERFAMILY SSF47413 60 119 7.04E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS08680 32e90e77cee323c104034655a7d6d7aa 126 SMART SM00530 62 116 0.0038 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS08680 32e90e77cee323c104034655a7d6d7aa 126 Gene3D G3DSA:1.10.260.40 40 125 3.4E-6 T 29-03-2018 THSYN_RS25740 bcc1df17fd5283c11d4354328a80c3e7 145 SUPERFAMILY SSF56300 39 89 4.05E-5 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS25740 bcc1df17fd5283c11d4354328a80c3e7 145 Gene3D G3DSA:3.60.21.10 30 126 2.4E-5 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS15855 b673380de6ae6453f01aa8ee2a9b1ac6 176 Pfam PF00583 Acetyltransferase (GNAT) family 41 125 1.4E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS15855 b673380de6ae6453f01aa8ee2a9b1ac6 176 Gene3D G3DSA:3.40.630.30 1 153 1.9E-15 T 29-03-2018 THSYN_RS15855 b673380de6ae6453f01aa8ee2a9b1ac6 176 SUPERFAMILY SSF55729 1 131 1.63E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS04270 d165e56a682b9ff66325bc447cbab2a4 109 Pfam PF01724 Domain of unknown function DUF29 19 64 3.7E-9 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS06790 d7b4aa2f1f3b1fe286341ea738694fef 227 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 94 160 2.0E-6 T 29-03-2018 IPR008792 Coenzyme PQQ synthesis D THSYN_RS22070 02472926b99c2ab57031ea5869d44de4 203 Pfam PF05685 Putative restriction endonuclease 14 63 2.7E-5 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS22070 02472926b99c2ab57031ea5869d44de4 203 Gene3D G3DSA:3.90.1570.10 66 144 6.8E-7 T 29-03-2018 THSYN_RS22070 02472926b99c2ab57031ea5869d44de4 203 Gene3D G3DSA:3.90.1570.10 3 65 1.4E-9 T 29-03-2018 THSYN_RS22070 02472926b99c2ab57031ea5869d44de4 203 SUPERFAMILY SSF52980 5 128 9.12E-9 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS09290 a76a1a5431cb5700e73ce880f3ff607d 377 Gene3D G3DSA:3.30.420.10 2 161 8.6E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS25615 120764de78ea7f76de7cb2d6d66f7678 285 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THSYN_RS25615 120764de78ea7f76de7cb2d6d66f7678 285 SUPERFAMILY SSF51735 1 242 1.88E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS25615 120764de78ea7f76de7cb2d6d66f7678 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.4E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS25615 120764de78ea7f76de7cb2d6d66f7678 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.4E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS25615 120764de78ea7f76de7cb2d6d66f7678 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.4E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS25615 120764de78ea7f76de7cb2d6d66f7678 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS25615 120764de78ea7f76de7cb2d6d66f7678 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS25615 120764de78ea7f76de7cb2d6d66f7678 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS25615 120764de78ea7f76de7cb2d6d66f7678 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS25615 120764de78ea7f76de7cb2d6d66f7678 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.9E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS25615 120764de78ea7f76de7cb2d6d66f7678 285 Pfam PF00106 short chain dehydrogenase 11 195 1.9E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THSYN_RS25615 120764de78ea7f76de7cb2d6d66f7678 285 Gene3D G3DSA:3.40.50.720 4 282 4.0E-66 T 29-03-2018 THSYN_RS18130 3e69e361871e158a086b084a34eed60b 839 Pfam PF08665 PglZ domain 462 631 3.3E-19 T 29-03-2018 IPR013973 PglZ domain THSYN_RS30820 f122ca1748898cb24661a95484cad5fb 86 Gene3D G3DSA:1.10.1220.10 1 40 7.0E-13 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS30820 f122ca1748898cb24661a95484cad5fb 86 SUPERFAMILY SSF47598 3 49 8.01E-11 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS30820 f122ca1748898cb24661a95484cad5fb 86 Pfam PF03869 Arc-like DNA binding domain 5 36 6.9E-5 T 29-03-2018 IPR005569 Arc-like DNA binding domain GO:0003677 THSYN_RS10190 dabb59cc961a5e84861abc4abebd1594 335 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 249 311 5.5E-16 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 THSYN_RS10190 dabb59cc961a5e84861abc4abebd1594 335 SUPERFAMILY SSF74653 166 178 1.44E-19 T 29-03-2018 THSYN_RS10190 dabb59cc961a5e84861abc4abebd1594 335 SUPERFAMILY SSF74653 222 329 1.44E-19 T 29-03-2018 THSYN_RS10190 dabb59cc961a5e84861abc4abebd1594 335 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 250 317 5.6E-14 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 THSYN_RS10190 dabb59cc961a5e84861abc4abebd1594 335 Gene3D G3DSA:3.30.1150.10 220 326 3.0E-21 T 29-03-2018 THSYN_RS04720 4b649631ce446118e436d4065210b660 336 Gene3D G3DSA:3.30.420.10 106 320 1.5E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS20325 ac8aabd2991b6f618b3d1d678c41e7c5 228 Pfam PF00483 Nucleotidyl transferase 3 119 2.6E-21 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THSYN_RS20325 ac8aabd2991b6f618b3d1d678c41e7c5 228 SUPERFAMILY SSF53448 1 219 5.86E-58 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS20325 ac8aabd2991b6f618b3d1d678c41e7c5 228 Gene3D G3DSA:3.90.550.10 1 224 3.6E-41 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS08730 dabaeb733a9bea3981416f9ca9310add 103 TIGRFAM TIGR04353 PqqD_rel_X: PqqD family protein, HPr-rel-A system 25 97 8.3E-15 T 29-03-2018 IPR027599 PqqD family protein, HPr-rel-A system THSYN_RS23530 e5de9c7d8c9ad5bdecb6ef8521d2cbd6 65 Pfam PF04255 Protein of unknown function (DUF433) 10 61 2.9E-17 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS23530 e5de9c7d8c9ad5bdecb6ef8521d2cbd6 65 SUPERFAMILY SSF46689 5 61 2.33E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS23530 e5de9c7d8c9ad5bdecb6ef8521d2cbd6 65 Gene3D G3DSA:1.10.10.10 9 65 2.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19230 bb088846111c7201ccea8bc9d234bb30 67 Pfam PF11103 Protein of unknown function (DUF2887) 3 66 3.0E-5 T 29-03-2018 IPR022573 Protein of unknown function DUF2887 THSYN_RS29710 e40dc915849aa6e4848ec39d252a966d 114 SMART SM00961 15 112 1.6E-46 T 29-03-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS29710 e40dc915849aa6e4848ec39d252a966d 114 SUPERFAMILY SSF55239 8 110 2.75E-40 T 29-03-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS29710 e40dc915849aa6e4848ec39d252a966d 114 Pfam PF00101 Ribulose bisphosphate carboxylase, small chain 17 109 3.3E-39 T 29-03-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS29710 e40dc915849aa6e4848ec39d252a966d 114 Gene3D G3DSA:3.30.190.10 12 113 6.3E-39 T 29-03-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THSYN_RS02425 2b9055869b62bf136962ad16ddc4ea24 594 Gene3D G3DSA:3.30.420.40 1 143 2.9E-28 T 29-03-2018 THSYN_RS02425 2b9055869b62bf136962ad16ddc4ea24 594 Pfam PF16861 Carbamoyltransferase C-terminus 412 579 1.9E-69 T 29-03-2018 IPR031730 Carbamoyltransferase, C-terminal THSYN_RS02425 2b9055869b62bf136962ad16ddc4ea24 594 SUPERFAMILY SSF53067 262 355 3.56E-14 T 29-03-2018 THSYN_RS02425 2b9055869b62bf136962ad16ddc4ea24 594 SUPERFAMILY SSF53067 123 208 3.56E-14 T 29-03-2018 THSYN_RS02425 2b9055869b62bf136962ad16ddc4ea24 594 SUPERFAMILY SSF53067 1 79 3.56E-14 T 29-03-2018 THSYN_RS02425 2b9055869b62bf136962ad16ddc4ea24 594 Pfam PF02543 Carbamoyltransferase N-terminus 3 351 7.5E-57 T 29-03-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 THSYN_RS30475 bd91d5b1fc60143d0146fa9963673383 329 SUPERFAMILY SSF53067 2 162 5.83E-20 T 29-03-2018 THSYN_RS30475 bd91d5b1fc60143d0146fa9963673383 329 Gene3D G3DSA:3.30.420.40 3 176 1.2E-17 T 29-03-2018 THSYN_RS30475 bd91d5b1fc60143d0146fa9963673383 329 Gene3D G3DSA:3.30.420.40 177 300 5.0E-4 T 29-03-2018 THSYN_RS30475 bd91d5b1fc60143d0146fa9963673383 329 SUPERFAMILY SSF53067 174 326 3.32E-15 T 29-03-2018 THSYN_RS23330 f0bb801d1a2965552daa37a52e9ae81c 435 Gene3D G3DSA:1.20.1250.20 218 430 1.3E-25 T 29-03-2018 THSYN_RS23330 f0bb801d1a2965552daa37a52e9ae81c 435 SUPERFAMILY SSF103473 5 431 3.01E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS23330 f0bb801d1a2965552daa37a52e9ae81c 435 Pfam PF07690 Major Facilitator Superfamily 22 254 8.1E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THSYN_RS23330 f0bb801d1a2965552daa37a52e9ae81c 435 Gene3D G3DSA:1.20.1250.20 8 209 1.3E-26 T 29-03-2018 THSYN_RS00590 aef104585599e77e266429189b447129 394 Pfam PF04326 Putative DNA-binding domain 14 116 1.6E-10 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 THSYN_RS00590 aef104585599e77e266429189b447129 394 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 289 388 2.7E-22 T 29-03-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain THSYN_RS28370 ea3d61f436bd14c0e356c8c35772137e 173 Pfam PF10517 Electron transfer DM13 76 168 1.4E-17 T 29-03-2018 IPR019545 DM13 domain THSYN_RS29505 98e80829c14bb3f1ca7f6c1654cee0ec 302 Pfam PF03466 LysR substrate binding domain 91 295 3.4E-50 T 29-03-2018 IPR005119 LysR, substrate-binding THSYN_RS29505 98e80829c14bb3f1ca7f6c1654cee0ec 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 1.8E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS29505 98e80829c14bb3f1ca7f6c1654cee0ec 302 SUPERFAMILY SSF53850 93 296 7.02E-45 T 29-03-2018 THSYN_RS29505 98e80829c14bb3f1ca7f6c1654cee0ec 302 Gene3D G3DSA:3.40.190.10 92 178 3.0E-19 T 29-03-2018 THSYN_RS29505 98e80829c14bb3f1ca7f6c1654cee0ec 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 5.8E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS29505 98e80829c14bb3f1ca7f6c1654cee0ec 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 5.8E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS29505 98e80829c14bb3f1ca7f6c1654cee0ec 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 5.8E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THSYN_RS29505 98e80829c14bb3f1ca7f6c1654cee0ec 302 SUPERFAMILY SSF46785 1 86 1.12E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS29505 98e80829c14bb3f1ca7f6c1654cee0ec 302 Gene3D G3DSA:1.10.10.10 1 86 2.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS29505 98e80829c14bb3f1ca7f6c1654cee0ec 302 Gene3D G3DSA:3.40.190.10 179 267 1.4E-23 T 29-03-2018 THSYN_RS11050 2ed67f8412e0f2d2186f06c2493b0419 327 Pfam PF00682 HMGL-like 14 258 2.5E-22 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 THSYN_RS11050 2ed67f8412e0f2d2186f06c2493b0419 327 SUPERFAMILY SSF51569 7 273 4.58E-39 T 29-03-2018 THSYN_RS11050 2ed67f8412e0f2d2186f06c2493b0419 327 Gene3D G3DSA:3.20.20.70 13 275 2.7E-41 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS01420 3dca44b837f249d04fe6f26196b4ee8b 69 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 25.963 T 29-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 THSYN_RS01420 3dca44b837f249d04fe6f26196b4ee8b 69 Gene3D G3DSA:2.20.25.10 8 66 3.5E-20 T 29-03-2018 THSYN_RS01420 3dca44b837f249d04fe6f26196b4ee8b 69 SUPERFAMILY SSF158997 1 54 1.02E-19 T 29-03-2018 THSYN_RS01420 3dca44b837f249d04fe6f26196b4ee8b 69 Pfam PF03966 Trm112p-like protein 2 40 2.6E-8 T 29-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 THSYN_RS32895 94b9ed8caf3d82c681778cd85e161377 858 TIGRFAM TIGR03986 TIGR03986: CRISPR-associated protein 93 744 2.5E-55 T 29-03-2018 IPR023825 CRISPR-associated RAMP BGP1436 THSYN_RS21060 8259a0fb1ec6212b0c050f7f98f73350 711 Gene3D G3DSA:2.60.120.430 29 178 1.5E-15 T 29-03-2018 THSYN_RS21060 8259a0fb1ec6212b0c050f7f98f73350 711 SUPERFAMILY SSF51445 205 280 4.06E-26 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS21060 8259a0fb1ec6212b0c050f7f98f73350 711 SUPERFAMILY SSF51445 456 586 4.06E-26 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS21060 8259a0fb1ec6212b0c050f7f98f73350 711 SUPERFAMILY SSF51445 310 315 4.06E-26 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS21060 8259a0fb1ec6212b0c050f7f98f73350 711 SUPERFAMILY SSF51445 342 426 4.06E-26 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS21060 8259a0fb1ec6212b0c050f7f98f73350 711 Gene3D G3DSA:2.60.40.1180 599 710 9.2E-22 T 29-03-2018 THSYN_RS21060 8259a0fb1ec6212b0c050f7f98f73350 711 Pfam PF12891 Glycoside hydrolase family 44 242 483 3.6E-77 T 29-03-2018 IPR024745 Glycoside hydrolase, family 44 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 THSYN_RS21060 8259a0fb1ec6212b0c050f7f98f73350 711 Gene3D G3DSA:3.20.20.80 206 598 1.0E-37 T 29-03-2018 THSYN_RS05380 30483782ce34239b12f3393fe5c42de1 334 Gene3D G3DSA:3.40.50.300 3 242 1.5E-29 T 29-03-2018 THSYN_RS05380 30483782ce34239b12f3393fe5c42de1 334 SUPERFAMILY SSF52540 10 235 2.72E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS05380 30483782ce34239b12f3393fe5c42de1 334 Pfam PF00685 Sulfotransferase domain 11 132 2.2E-5 T 29-03-2018 IPR000863 Sulfotransferase domain GO:0008146 THSYN_RS15250 39e04137f28a8d154dc47938762d70cb 47 Pfam PF08085 Entericidin EcnA/B family 20 40 8.6E-10 T 29-03-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 THSYN_RS29325 fe3230e2c04382f904ec64734ecd6558 91 Pfam PF03055 Retinal pigment epithelial membrane protein 3 83 7.6E-12 T 29-03-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 THSYN_RS06955 286923f5c771a4ab3a31de46d8a5dd1a 443 Gene3D G3DSA:3.50.50.60 1 427 2.3E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS06955 286923f5c771a4ab3a31de46d8a5dd1a 443 SUPERFAMILY SSF51905 1 282 2.33E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS06955 286923f5c771a4ab3a31de46d8a5dd1a 443 SUPERFAMILY SSF51905 372 415 2.33E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS06955 286923f5c771a4ab3a31de46d8a5dd1a 443 Pfam PF01593 Flavin containing amine oxidoreductase 12 408 2.6E-33 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THSYN_RS06955 286923f5c771a4ab3a31de46d8a5dd1a 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 7.6E-5 T 29-03-2018 THSYN_RS06955 286923f5c771a4ab3a31de46d8a5dd1a 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 7.6E-5 T 29-03-2018 THSYN_RS00410 c3664fb969ab5afa28635e3466f85531 460 PIRSF PIRSF006060 2 456 2.2E-85 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THSYN_RS00410 c3664fb969ab5afa28635e3466f85531 460 Pfam PF13520 Amino acid permease 25 427 7.1E-55 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THSYN_RS30615 23ba2ba9ce72e7ff7655b8c35103650b 269 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS30615 23ba2ba9ce72e7ff7655b8c35103650b 269 SMART SM00382 60 251 9.7E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS30615 23ba2ba9ce72e7ff7655b8c35103650b 269 SUPERFAMILY SSF52540 38 267 3.66E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS30615 23ba2ba9ce72e7ff7655b8c35103650b 269 Pfam PF00005 ABC transporter 51 199 8.4E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS30615 23ba2ba9ce72e7ff7655b8c35103650b 269 Gene3D G3DSA:3.40.50.300 37 267 4.6E-60 T 29-03-2018 THSYN_RS18895 005e9ef641953803ff79c18d5b5e62fa 388 Gene3D G3DSA:3.20.20.70 1 316 3.0E-18 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS18895 005e9ef641953803ff79c18d5b5e62fa 388 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 262 353 1.4E-12 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain THSYN_RS18895 005e9ef641953803ff79c18d5b5e62fa 388 SUPERFAMILY SSF102114 5 335 1.96E-23 T 29-03-2018 THSYN_RS12070 dbd52629d40a1f5d17acc5442bbd4832 150 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 8 140 10.58 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS12070 dbd52629d40a1f5d17acc5442bbd4832 150 Pfam PF01850 PIN domain 8 135 8.6E-17 T 29-03-2018 IPR002716 PIN domain THSYN_RS12070 dbd52629d40a1f5d17acc5442bbd4832 150 Gene3D G3DSA:3.40.50.1010 6 137 7.7E-23 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS12070 dbd52629d40a1f5d17acc5442bbd4832 150 SUPERFAMILY SSF88723 8 139 2.8E-18 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS00625 0e67f402a0abc5818a0cb8b8efbff55c 73 Gene3D G3DSA:3.40.50.2300 21 71 5.7E-6 T 29-03-2018 THSYN_RS00625 0e67f402a0abc5818a0cb8b8efbff55c 73 SUPERFAMILY SSF52172 23 67 9.36E-6 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS12355 5302ca30e0ecd5b0595a2463b1d34f1e 445 Pfam PF16268 Domain of unknown function (DUF4921) 15 439 6.7E-214 T 29-03-2018 IPR032576 Domain of unknown function DUF4921 THSYN_RS12355 5302ca30e0ecd5b0595a2463b1d34f1e 445 SUPERFAMILY SSF54197 22 135 5.32E-22 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 THSYN_RS12355 5302ca30e0ecd5b0595a2463b1d34f1e 445 SUPERFAMILY SSF54197 183 264 5.32E-22 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 THSYN_RS12355 5302ca30e0ecd5b0595a2463b1d34f1e 445 Gene3D G3DSA:3.30.428.10 61 265 5.0E-39 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 THSYN_RS28675 69cd7fa9e4876bf1285969807463cd82 260 Pfam PF05742 Transport and Golgi organisation 2 3 167 5.1E-20 T 29-03-2018 IPR008551 Transport and Golgi organisation protein 2 THSYN_RS00400 7c0090d1ecc5aaaebe5b4796a21942cc 816 Pfam PF00563 EAL domain 562 791 1.0E-68 T 29-03-2018 IPR001633 EAL domain THSYN_RS00400 7c0090d1ecc5aaaebe5b4796a21942cc 816 SMART SM00267 371 543 4.5E-61 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS00400 7c0090d1ecc5aaaebe5b4796a21942cc 816 SUPERFAMILY SSF141868 562 801 6.28E-75 T 29-03-2018 IPR001633 EAL domain THSYN_RS00400 7c0090d1ecc5aaaebe5b4796a21942cc 816 Pfam PF00990 Diguanylate cyclase, GGDEF domain 382 538 6.6E-47 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS00400 7c0090d1ecc5aaaebe5b4796a21942cc 816 Gene3D G3DSA:3.30.70.270 370 545 2.6E-56 T 29-03-2018 THSYN_RS00400 7c0090d1ecc5aaaebe5b4796a21942cc 816 Gene3D G3DSA:3.20.20.450 546 807 6.4E-84 T 29-03-2018 IPR001633 EAL domain THSYN_RS00400 7c0090d1ecc5aaaebe5b4796a21942cc 816 SUPERFAMILY SSF55073 387 543 3.77E-47 T 29-03-2018 IPR029787 Nucleotide cyclase THSYN_RS00400 7c0090d1ecc5aaaebe5b4796a21942cc 816 SMART SM00052 555 796 1.3E-73 T 29-03-2018 IPR001633 EAL domain THSYN_RS00400 7c0090d1ecc5aaaebe5b4796a21942cc 816 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 380 541 1.1E-44 T 29-03-2018 IPR000160 GGDEF domain THSYN_RS03280 36baba5a710089e7f694f2a3b85e4f7e 118 Gene3D G3DSA:3.30.460.10 1 118 2.0E-35 T 29-03-2018 THSYN_RS03280 36baba5a710089e7f694f2a3b85e4f7e 118 SUPERFAMILY SSF81301 1 110 5.4E-39 T 29-03-2018 THSYN_RS03280 36baba5a710089e7f694f2a3b85e4f7e 118 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 4.1E-27 T 29-03-2018 THSYN_RS03280 36baba5a710089e7f694f2a3b85e4f7e 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 24.857 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS THSYN_RS03280 36baba5a710089e7f694f2a3b85e4f7e 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 1.3E-36 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS THSYN_RS22300 024d61f962eece92d170d89e298cd620 239 Pfam PF07589 PEP-CTERM motif 213 236 2.3E-7 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS22300 024d61f962eece92d170d89e298cd620 239 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 214 237 3.1E-6 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS01740 63803801c4a856b332f7cc5d6bfdf820 364 SUPERFAMILY SSF56176 12 176 1.21E-27 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THSYN_RS01740 63803801c4a856b332f7cc5d6bfdf820 364 Pfam PF02913 FAD linked oxidases, C-terminal domain 336 359 2.0E-5 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THSYN_RS01740 63803801c4a856b332f7cc5d6bfdf820 364 Pfam PF01565 FAD binding domain 12 138 1.5E-16 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THSYN_RS01740 63803801c4a856b332f7cc5d6bfdf820 364 Gene3D G3DSA:1.10.45.10 328 363 2.8E-9 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 THSYN_RS01740 63803801c4a856b332f7cc5d6bfdf820 364 SUPERFAMILY SSF55103 188 363 3.6E-17 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THSYN_RS01740 63803801c4a856b332f7cc5d6bfdf820 364 Gene3D G3DSA:3.30.465.10 55 200 1.0E-24 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THSYN_RS15845 62f460737ce3b5e004fba9005a0d056c 108 Pfam PF07007 Lysozyme inhibitor LprI 10 100 9.2E-18 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal THSYN_RS23985 8b53d62bcc9a4a41ca27d70235e8742f 125 SUPERFAMILY SSF46955 24 123 1.88E-21 T 29-03-2018 IPR009061 Putative DNA-binding domain THSYN_RS23985 8b53d62bcc9a4a41ca27d70235e8742f 125 Pfam PF13411 MerR HTH family regulatory protein 26 94 2.3E-23 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THSYN_RS23985 8b53d62bcc9a4a41ca27d70235e8742f 125 Gene3D G3DSA:1.10.1660.10 21 125 6.3E-30 T 29-03-2018 THSYN_RS23985 8b53d62bcc9a4a41ca27d70235e8742f 125 SMART SM00422 26 96 6.3E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THSYN_RS19875 ceb6307a39e708547e7234a43a95af12 632 Pfam PF01496 V-type ATPase 116kDa subunit family 522 623 6.2E-12 T 29-03-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS19875 ceb6307a39e708547e7234a43a95af12 632 Pfam PF01496 V-type ATPase 116kDa subunit family 215 386 3.6E-13 T 29-03-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS00780 f18bfc1abfa1249df0d63872f22c2ac3 203 Gene3D G3DSA:3.40.50.150 3 201 6.5E-27 T 29-03-2018 THSYN_RS00780 f18bfc1abfa1249df0d63872f22c2ac3 203 Pfam PF13649 Methyltransferase domain 42 130 6.1E-13 T 29-03-2018 THSYN_RS00780 f18bfc1abfa1249df0d63872f22c2ac3 203 SUPERFAMILY SSF53335 7 163 1.23E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS13565 f34d91aeb6490284cb26b159bdbe28ba 443 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 200 415 1.3E-50 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 THSYN_RS13565 f34d91aeb6490284cb26b159bdbe28ba 443 SMART SM00646 260 415 3.6E-56 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 THSYN_RS13565 f34d91aeb6490284cb26b159bdbe28ba 443 Gene3D G3DSA:3.40.630.40 195 424 6.2E-57 T 29-03-2018 THSYN_RS13565 f34d91aeb6490284cb26b159bdbe28ba 443 Pfam PF11741 AMIN domain 42 141 4.2E-13 T 29-03-2018 IPR021731 AMIN domain THSYN_RS13565 f34d91aeb6490284cb26b159bdbe28ba 443 SUPERFAMILY SSF53187 342 419 7.85E-55 T 29-03-2018 THSYN_RS13565 f34d91aeb6490284cb26b159bdbe28ba 443 SUPERFAMILY SSF53187 198 294 7.85E-55 T 29-03-2018 THSYN_RS19565 5d5c412f5b8ce289d446c9f8ff7b589c 284 Pfam PF07589 PEP-CTERM motif 260 282 1.6E-5 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS19625 1e26e3da73a7ae6eef91663ffa152936 100 SUPERFAMILY SSF54909 2 98 7.15E-30 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel THSYN_RS19625 1e26e3da73a7ae6eef91663ffa152936 100 Pfam PF03795 YCII-related domain 2 95 4.1E-27 T 29-03-2018 IPR005545 YCII-related THSYN_RS19625 1e26e3da73a7ae6eef91663ffa152936 100 Gene3D G3DSA:3.30.70.1060 1 98 1.5E-27 T 29-03-2018 THSYN_RS17105 cd8136e10c68e34163b5caaa8e257870 127 SUPERFAMILY SSF52540 19 114 2.26E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17105 cd8136e10c68e34163b5caaa8e257870 127 Pfam PF13173 AAA domain 19 123 4.1E-15 T 29-03-2018 THSYN_RS04120 8d099f78302e7c316e3d508793e4aca6 342 SUPERFAMILY SSF111369 46 255 2.35E-24 T 29-03-2018 THSYN_RS04120 8d099f78302e7c316e3d508793e4aca6 342 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 35 327 6.7E-59 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS04120 8d099f78302e7c316e3d508793e4aca6 342 Pfam PF00529 HlyD membrane-fusion protein of T1SS 16 250 1.9E-7 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THSYN_RS04120 8d099f78302e7c316e3d508793e4aca6 342 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 53 253 1.1E-28 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS04120 8d099f78302e7c316e3d508793e4aca6 342 Gene3D G3DSA:1.20.1600.10 62 274 5.9E-18 T 29-03-2018 THSYN_RS12930 82bec0c2be80abd3c18dd19502be71c4 162 Pfam PF08808 RES domain 3 148 3.5E-24 T 29-03-2018 IPR014914 RES domain THSYN_RS12930 82bec0c2be80abd3c18dd19502be71c4 162 SMART SM00953 15 140 9.4E-25 T 29-03-2018 IPR014914 RES domain THSYN_RS29805 f07f82a7cadc21f4615422a0fb25b3b0 311 Pfam PF04536 TPM domain 41 160 6.4E-36 T 29-03-2018 IPR007621 TPM domain THSYN_RS20845 53966bbfe4148ea5708938126ff663a8 392 SUPERFAMILY SSF56935 21 392 8.42E-18 T 29-03-2018 THSYN_RS20845 53966bbfe4148ea5708938126ff663a8 392 Gene3D G3DSA:2.40.160.10 12 392 7.4E-33 T 29-03-2018 THSYN_RS04220 8d1f0fccc6ff04867d3e1ae41f02ebaf 121 SUPERFAMILY SSF50118 3 92 2.18E-9 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS04220 8d1f0fccc6ff04867d3e1ae41f02ebaf 121 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 6 91 5.4E-10 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS04220 8d1f0fccc6ff04867d3e1ae41f02ebaf 121 Gene3D G3DSA:2.30.30.110 1 107 1.1E-10 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS04025 655babca98a191759da96d222b4f70de 163 TIGRFAM TIGR01616 nitro_assoc: nitrogenase-associated protein 10 135 5.6E-50 T 29-03-2018 IPR006503 Nitrogenase-associated protein THSYN_RS04025 655babca98a191759da96d222b4f70de 163 SUPERFAMILY SSF52833 12 126 1.06E-25 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS04025 655babca98a191759da96d222b4f70de 163 Pfam PF03960 ArsC family 65 116 5.5E-8 T 29-03-2018 IPR006660 Arsenate reductase-like THSYN_RS04025 655babca98a191759da96d222b4f70de 163 Gene3D G3DSA:3.40.30.10 11 123 2.7E-15 T 29-03-2018 THSYN_RS31670 9c8a0ad7d8ce75a313a0480bc3c550f0 477 Gene3D G3DSA:1.20.1250.20 244 457 9.8E-8 T 29-03-2018 THSYN_RS31670 9c8a0ad7d8ce75a313a0480bc3c550f0 477 SUPERFAMILY SSF103473 35 446 4.97E-22 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS31670 9c8a0ad7d8ce75a313a0480bc3c550f0 477 PIRSF PIRSF016565 20 471 6.8E-116 T 29-03-2018 IPR026036 PucC protein THSYN_RS31670 9c8a0ad7d8ce75a313a0480bc3c550f0 477 Gene3D G3DSA:1.20.1250.20 32 240 1.8E-13 T 29-03-2018 THSYN_RS31670 9c8a0ad7d8ce75a313a0480bc3c550f0 477 Pfam PF03209 PUCC protein 55 457 1.1E-135 T 29-03-2018 IPR004896 PucC-related THSYN_RS28895 fbfa1cda40bb5c952a31743afa171008 598 Pfam PF09820 Predicted AAA-ATPase 4 301 6.5E-66 T 29-03-2018 IPR018631 AAA-ATPase-like domain THSYN_RS04210 cb7dac21185d15b7db4c0013c363edb2 560 Gene3D G3DSA:3.40.50.300 146 333 9.9E-5 T 29-03-2018 THSYN_RS04210 cb7dac21185d15b7db4c0013c363edb2 560 SUPERFAMILY SSF52540 170 200 1.88E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04210 cb7dac21185d15b7db4c0013c363edb2 560 SUPERFAMILY SSF52540 229 244 1.88E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04210 cb7dac21185d15b7db4c0013c363edb2 560 SUPERFAMILY SSF52540 274 348 1.88E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15655 06b12a4295224dd97b0497f74849f159 283 Gene3D G3DSA:3.60.60.10 1 283 7.8E-74 T 29-03-2018 THSYN_RS15655 06b12a4295224dd97b0497f74849f159 283 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 8 261 3.8E-57 T 29-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal THSYN_RS15655 06b12a4295224dd97b0497f74849f159 283 SUPERFAMILY SSF56235 8 268 9.26E-73 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS21160 ef2049b0fe973328296a65991b9bb1fe 460 Pfam PF13598 Domain of unknown function (DUF4139) 170 458 5.9E-8 T 29-03-2018 IPR011935 Conserved hypothetical protein CHP02231 THSYN_RS12555 aaf8dbd8c45329a69c6dab7d3843cad9 271 SUPERFAMILY SSF56436 35 265 5.65E-70 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS12555 aaf8dbd8c45329a69c6dab7d3843cad9 271 Pfam PF03781 Sulfatase-modifying factor enzyme 1 38 263 7.6E-54 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS12555 aaf8dbd8c45329a69c6dab7d3843cad9 271 Gene3D G3DSA:3.90.1580.10 23 270 3.0E-67 T 29-03-2018 THSYN_RS10240 fda0889779f642bf4658ed229071ab29 356 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 5 355 6.7E-105 T 29-03-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 THSYN_RS10240 fda0889779f642bf4658ed229071ab29 356 Pfam PF03739 Predicted permease YjgP/YjgQ family 8 354 5.8E-61 T 29-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 THSYN_RS04990 7e523294a0fee46286d23544c193926d 293 Gene3D G3DSA:3.40.50.300 1 236 3.6E-61 T 29-03-2018 THSYN_RS04990 7e523294a0fee46286d23544c193926d 293 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS04990 7e523294a0fee46286d23544c193926d 293 SMART SM00382 29 203 6.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS04990 7e523294a0fee46286d23544c193926d 293 SUPERFAMILY SSF52540 2 216 7.24E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04990 7e523294a0fee46286d23544c193926d 293 Pfam PF00005 ABC transporter 21 155 1.2E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS28360 f1ecb2e8bdd7ae83a58dd9d6f56df1fc 95 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 8 92 3.3E-36 T 29-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 THSYN_RS18940 83569aef8314d3e79a42dd9a11d41178 360 Gene3D G3DSA:2.40.160.20 83 360 6.7E-10 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THSYN_RS18940 83569aef8314d3e79a42dd9a11d41178 360 SUPERFAMILY SSF56935 119 360 6.41E-5 T 29-03-2018 THSYN_RS30415 0934d8e2bcbcefadccfa5ab00aca8d09 363 SUPERFAMILY SSF52172 4 95 6.12E-13 T 29-03-2018 IPR011006 CheY-like superfamily THSYN_RS30415 0934d8e2bcbcefadccfa5ab00aca8d09 363 Gene3D G3DSA:3.40.50.2300 1 125 6.4E-13 T 29-03-2018 THSYN_RS30415 0934d8e2bcbcefadccfa5ab00aca8d09 363 Pfam PF00072 Response regulator receiver domain 17 102 3.9E-6 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THSYN_RS21970 ea6108eaa30d6933d343ffe80d2a748d 279 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 29-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 THSYN_RS21970 ea6108eaa30d6933d343ffe80d2a748d 279 SUPERFAMILY SSF56219 2 272 5.37E-79 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase THSYN_RS21970 ea6108eaa30d6933d343ffe80d2a748d 279 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 263 1.3E-15 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase THSYN_RS21970 ea6108eaa30d6933d343ffe80d2a748d 279 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 3 270 1.1E-84 T 29-03-2018 THSYN_RS21970 ea6108eaa30d6933d343ffe80d2a748d 279 Gene3D G3DSA:3.60.10.10 1 272 1.7E-49 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase THSYN_RS21970 ea6108eaa30d6933d343ffe80d2a748d 279 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 3 270 2.6E-75 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 THSYN_RS02170 2439b0467551b3d9ef15f4a81d3d5a00 226 SUPERFAMILY SSF48613 15 220 2.14E-29 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 THSYN_RS02170 2439b0467551b3d9ef15f4a81d3d5a00 226 Gene3D G3DSA:1.20.910.10 7 223 4.9E-29 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 THSYN_RS19780 edf5d0912ba292a2f7dcb4e83dcd760b 82 Gene3D G3DSA:3.30.70.20 51 78 0.011 T 29-03-2018 THSYN_RS19780 edf5d0912ba292a2f7dcb4e83dcd760b 82 Pfam PF00037 4Fe-4S binding domain 5 25 2.1E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS19780 edf5d0912ba292a2f7dcb4e83dcd760b 82 Gene3D G3DSA:3.30.70.20 2 50 4.6E-16 T 29-03-2018 THSYN_RS19780 edf5d0912ba292a2f7dcb4e83dcd760b 82 SUPERFAMILY SSF54862 5 71 4.49E-20 T 29-03-2018 THSYN_RS19780 edf5d0912ba292a2f7dcb4e83dcd760b 82 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS32025 ad98d089e0d4e1d597a4760e02579755 170 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 9 166 2.4E-66 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 THSYN_RS32025 ad98d089e0d4e1d597a4760e02579755 170 Gene3D G3DSA:3.30.230.60 7 167 6.5E-72 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 THSYN_RS32025 ad98d089e0d4e1d597a4760e02579755 170 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 8 166 1.1E-70 T 29-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 THSYN_RS32025 ad98d089e0d4e1d597a4760e02579755 170 SUPERFAMILY SSF54211 7 167 3.87E-62 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS08175 1c19c746c70596fd92b704a3907e67ef 1293 SUPERFAMILY SSF52151 41 94 3.31E-30 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS08175 1c19c746c70596fd92b704a3907e67ef 1293 SUPERFAMILY SSF52151 604 915 3.31E-30 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THSYN_RS08175 1c19c746c70596fd92b704a3907e67ef 1293 Pfam PF01734 Patatin-like phospholipase 44 99 4.0E-7 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 THSYN_RS08175 1c19c746c70596fd92b704a3907e67ef 1293 Gene3D G3DSA:3.40.1090.10 712 909 1.0E-10 T 29-03-2018 THSYN_RS08175 1c19c746c70596fd92b704a3907e67ef 1293 Gene3D G3DSA:3.40.1090.10 31 175 8.4E-14 T 29-03-2018 THSYN_RS15105 45e6f2a0dcbe9216fa49cefad2902039 413 Pfam PF01261 Xylose isomerase-like TIM barrel 71 258 4.8E-7 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain THSYN_RS15105 45e6f2a0dcbe9216fa49cefad2902039 413 SUPERFAMILY SSF51658 24 273 1.33E-22 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain THSYN_RS15105 45e6f2a0dcbe9216fa49cefad2902039 413 Gene3D G3DSA:3.20.20.150 13 408 1.2E-34 T 29-03-2018 THSYN_RS03950 1cab4a9ee8f32976ff6d4bb2264c3c41 548 PRINTS PR01217 Proline rich extensin signature 268 293 9.0E-11 T 29-03-2018 THSYN_RS03950 1cab4a9ee8f32976ff6d4bb2264c3c41 548 PRINTS PR01217 Proline rich extensin signature 123 135 9.0E-11 T 29-03-2018 THSYN_RS03950 1cab4a9ee8f32976ff6d4bb2264c3c41 548 PRINTS PR01217 Proline rich extensin signature 245 262 9.0E-11 T 29-03-2018 THSYN_RS03950 1cab4a9ee8f32976ff6d4bb2264c3c41 548 PRINTS PR01217 Proline rich extensin signature 164 176 9.0E-11 T 29-03-2018 THSYN_RS03950 1cab4a9ee8f32976ff6d4bb2264c3c41 548 PRINTS PR01217 Proline rich extensin signature 203 224 9.0E-11 T 29-03-2018 THSYN_RS28585 654f3232edc857d8bd2c8ccd0f1c62b5 178 Gene3D G3DSA:3.40.630.30 30 174 1.0E-16 T 29-03-2018 THSYN_RS28585 654f3232edc857d8bd2c8ccd0f1c62b5 178 Pfam PF00583 Acetyltransferase (GNAT) family 45 152 1.6E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS28585 654f3232edc857d8bd2c8ccd0f1c62b5 178 SUPERFAMILY SSF55729 25 153 2.34E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS21030 916351fd482347b89a1cd1c27cf083bd 144 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 132 10.946 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS21030 916351fd482347b89a1cd1c27cf083bd 144 Gene3D G3DSA:3.40.50.1010 3 141 1.7E-24 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS21030 916351fd482347b89a1cd1c27cf083bd 144 Pfam PF01850 PIN domain 6 127 3.1E-15 T 29-03-2018 IPR002716 PIN domain THSYN_RS21030 916351fd482347b89a1cd1c27cf083bd 144 SUPERFAMILY SSF88723 4 134 3.64E-32 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS24445 6827f51382bb0ad039e12ab633b046bd 124 Pfam PF08765 Mor transcription activator family 14 121 7.8E-18 T 29-03-2018 IPR014875 Mor transcription activator THSYN_RS24445 6827f51382bb0ad039e12ab633b046bd 124 Gene3D G3DSA:1.10.10.60 68 123 4.0E-12 T 29-03-2018 THSYN_RS24445 6827f51382bb0ad039e12ab633b046bd 124 SUPERFAMILY SSF46689 15 116 6.63E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS28485 4622bcc8af2de62ff8e26fa624d36406 448 Pfam PF03065 Glycosyl hydrolase family 57 86 317 8.3E-22 T 29-03-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 THSYN_RS28485 4622bcc8af2de62ff8e26fa624d36406 448 SUPERFAMILY SSF88713 4 300 1.6E-46 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS28485 4622bcc8af2de62ff8e26fa624d36406 448 Gene3D G3DSA:3.20.110.10 1 84 0.084 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain THSYN_RS28485 4622bcc8af2de62ff8e26fa624d36406 448 Gene3D G3DSA:3.20.110.10 207 296 1.4E-12 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain THSYN_RS28485 4622bcc8af2de62ff8e26fa624d36406 448 Gene3D G3DSA:3.20.110.10 85 206 7.8E-21 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain THSYN_RS33195 09a8daed51446f8744c4345f955541ec 167 Gene3D G3DSA:3.40.30.10 79 164 1.0E-9 T 29-03-2018 THSYN_RS33195 09a8daed51446f8744c4345f955541ec 167 SUPERFAMILY SSF52833 16 161 6.6E-44 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS33195 09a8daed51446f8744c4345f955541ec 167 PIRSF PIRSF000216 2 165 1.7E-41 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS33195 09a8daed51446f8744c4345f955541ec 167 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 20 160 9.7E-39 T 29-03-2018 THSYN_RS32395 63aa1200348d2d10be4815b00107491f 142 Gene3D G3DSA:3.40.50.1010 13 140 1.3E-17 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS32395 63aa1200348d2d10be4815b00107491f 142 SUPERFAMILY SSF88723 18 142 7.57E-20 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS32395 63aa1200348d2d10be4815b00107491f 142 Pfam PF01850 PIN domain 18 136 7.2E-13 T 29-03-2018 IPR002716 PIN domain THSYN_RS04250 ed9000c6e77482e1cff6ae5881ce2025 289 Pfam PF13289 SIR2-like domain 132 266 1.6E-7 T 29-03-2018 THSYN_RS10270 05963fae100a4e4894ae9892fc8f9842 102 Pfam PF14082 Domain of unknown function (DUF4263) 34 87 2.1E-10 T 29-03-2018 IPR025359 Protein of unknown function DUF4263 THSYN_RS28280 d8a0a5191c90b1c58430a40f6a414a04 66 Pfam PF11127 Protein of unknown function (DUF2892) 2 58 2.4E-15 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 THSYN_RS26300 59765df2f7ce543f17ac507241e73f3e 207 Gene3D G3DSA:3.40.50.300 23 177 1.4E-6 T 29-03-2018 THSYN_RS26300 59765df2f7ce543f17ac507241e73f3e 207 Pfam PF06414 Zeta toxin 3 164 1.6E-9 T 29-03-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 THSYN_RS26300 59765df2f7ce543f17ac507241e73f3e 207 Gene3D G3DSA:3.40.50.300 2 22 1.3E-5 T 29-03-2018 THSYN_RS26300 59765df2f7ce543f17ac507241e73f3e 207 SUPERFAMILY SSF52540 4 147 1.25E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31190 d7c7016e06174af67f8ec99e9c286df2 316 Gene3D G3DSA:3.40.50.300 24 313 2.4E-34 T 29-03-2018 THSYN_RS31190 d7c7016e06174af67f8ec99e9c286df2 316 SUPERFAMILY SSF52540 25 307 4.35E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS31190 d7c7016e06174af67f8ec99e9c286df2 316 Pfam PF13614 AAA domain 25 212 9.9E-24 T 29-03-2018 IPR025669 AAA domain THSYN_RS08075 30e2e3b9adff19f5c8dfd87373ff1f7d 267 Pfam PF01435 Peptidase family M48 64 251 1.9E-39 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THSYN_RS08075 30e2e3b9adff19f5c8dfd87373ff1f7d 267 Gene3D G3DSA:3.30.2010.10 54 146 2.1E-22 T 29-03-2018 THSYN_RS32835 a0fd1bec4a2104c3491e8efd1a8ae6e5 284 Gene3D G3DSA:1.25.40.10 72 145 0.032 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS32835 a0fd1bec4a2104c3491e8efd1a8ae6e5 284 SUPERFAMILY SSF144059 3 262 7.59E-90 T 29-03-2018 THSYN_RS32835 a0fd1bec4a2104c3491e8efd1a8ae6e5 284 Gene3D G3DSA:1.25.40.10 1 71 2.0E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS32835 a0fd1bec4a2104c3491e8efd1a8ae6e5 284 Pfam PF07024 ImpE protein 138 258 3.3E-46 T 29-03-2018 IPR009211 Predicted virulence protein, SciE type THSYN_RS32835 a0fd1bec4a2104c3491e8efd1a8ae6e5 284 PIRSF PIRSF029288 2 265 5.3E-92 T 29-03-2018 IPR009211 Predicted virulence protein, SciE type THSYN_RS08190 79c87f41997b4eb4acdcdad664a06722 309 SUPERFAMILY SSF54637 9 109 1.16E-5 T 29-03-2018 IPR029069 HotDog domain THSYN_RS08190 79c87f41997b4eb4acdcdad664a06722 309 Gene3D G3DSA:3.10.129.10 3 132 6.9E-6 T 29-03-2018 THSYN_RS17630 700b1ff27c43896c868b136ef20a691a 86 Pfam PF11154 Protein of unknown function (DUF2934) 44 73 2.1E-11 T 29-03-2018 IPR021327 Protein of unknown function DUF2934 THSYN_RS11565 3620b1d0249c72e38a3ffba2e74eb915 385 Pfam PF14319 Transposase zinc-binding domain 16 114 9.0E-32 T 29-03-2018 IPR026889 Transposase zinc-binding domain THSYN_RS11565 3620b1d0249c72e38a3ffba2e74eb915 385 Pfam PF04986 Putative transposase 140 320 2.4E-56 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THSYN_RS14370 0f81fc7c4c428477d06b7c1ed8b1b010 224 Gene3D G3DSA:1.25.40.10 16 215 4.7E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS09620 d5a1a8d78a4cf0e7b2a8389531dee799 475 SUPERFAMILY SSF56762 1 450 6.54E-133 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09620 d5a1a8d78a4cf0e7b2a8389531dee799 475 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 441 450 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THSYN_RS09620 d5a1a8d78a4cf0e7b2a8389531dee799 475 Gene3D G3DSA:1.10.645.10 249 450 3.1E-41 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09620 d5a1a8d78a4cf0e7b2a8389531dee799 475 Gene3D G3DSA:1.10.645.10 1 248 4.9E-64 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09620 d5a1a8d78a4cf0e7b2a8389531dee799 475 Pfam PF00374 Nickel-dependent hydrogenase 40 116 1.8E-17 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THSYN_RS09620 d5a1a8d78a4cf0e7b2a8389531dee799 475 Pfam PF00374 Nickel-dependent hydrogenase 266 450 1.5E-11 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THSYN_RS05915 e09fb41c6132891a113a29063d539b8b 359 SUPERFAMILY SSF53756 2 357 2.39E-80 T 29-03-2018 THSYN_RS05915 e09fb41c6132891a113a29063d539b8b 359 Gene3D G3DSA:3.40.50.2000 1 169 2.7E-22 T 29-03-2018 THSYN_RS05915 e09fb41c6132891a113a29063d539b8b 359 Pfam PF00534 Glycosyl transferases group 1 177 334 4.1E-32 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS05915 e09fb41c6132891a113a29063d539b8b 359 Gene3D G3DSA:3.40.50.2000 170 341 1.1E-43 T 29-03-2018 THSYN_RS05915 e09fb41c6132891a113a29063d539b8b 359 Pfam PF13439 Glycosyltransferase Family 4 14 160 3.2E-19 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS18100 ae8e606ff6e27f19e1a6c49d9511c15b 168 Pfam PF11848 Domain of unknown function (DUF3368) 121 164 2.8E-12 T 29-03-2018 IPR021799 Protein of unknown function DUF3368 THSYN_RS29420 9370fe0854f2c03570fd9f27bdc1d4b7 301 Pfam PF04116 Fatty acid hydroxylase superfamily 83 219 9.5E-30 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 THSYN_RS00755 1faccacdeb752decf244c64ad28599a6 263 SUPERFAMILY SSF52129 3 142 2.82E-10 T 29-03-2018 IPR029030 Caspase-like domain THSYN_RS00755 1faccacdeb752decf244c64ad28599a6 263 SUPERFAMILY SSF52129 180 223 2.82E-10 T 29-03-2018 IPR029030 Caspase-like domain THSYN_RS00755 1faccacdeb752decf244c64ad28599a6 263 Gene3D G3DSA:3.40.50.1460 2 262 5.3E-54 T 29-03-2018 THSYN_RS00755 1faccacdeb752decf244c64ad28599a6 263 Pfam PF00656 Caspase domain 3 255 2.1E-36 T 29-03-2018 THSYN_RS05910 d520d732728109d7db70d718786e94ab 292 Gene3D G3DSA:3.20.20.370 29 282 6.3E-42 T 29-03-2018 THSYN_RS05910 d520d732728109d7db70d718786e94ab 292 SUPERFAMILY SSF88713 28 213 1.06E-38 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS05910 d520d732728109d7db70d718786e94ab 292 Pfam PF01522 Polysaccharide deacetylase 63 199 1.9E-31 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 THSYN_RS17030 5c6e78b49a41bcb5499412715ca98d89 2058 SUPERFAMILY SSF54001 254 276 2.7E-6 T 29-03-2018 THSYN_RS17030 5c6e78b49a41bcb5499412715ca98d89 2058 SUPERFAMILY SSF54001 142 198 2.7E-6 T 29-03-2018 THSYN_RS17030 5c6e78b49a41bcb5499412715ca98d89 2058 Pfam PF05593 RHS Repeat 1502 1532 2.7E-5 T 29-03-2018 IPR031325 RHS repeat THSYN_RS17030 5c6e78b49a41bcb5499412715ca98d89 2058 Pfam PF05593 RHS Repeat 1437 1471 3.7E-7 T 29-03-2018 IPR031325 RHS repeat THSYN_RS17030 5c6e78b49a41bcb5499412715ca98d89 2058 Pfam PF01841 Transglutaminase-like superfamily 140 263 1.5E-5 T 29-03-2018 IPR002931 Transglutaminase-like THSYN_RS17030 5c6e78b49a41bcb5499412715ca98d89 2058 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1437 1470 1.1E-6 T 29-03-2018 IPR006530 YD repeat THSYN_RS17030 5c6e78b49a41bcb5499412715ca98d89 2058 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 956 984 2.4E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS17030 5c6e78b49a41bcb5499412715ca98d89 2058 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1125 1153 5.5E-4 T 29-03-2018 IPR006530 YD repeat THSYN_RS17030 5c6e78b49a41bcb5499412715ca98d89 2058 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1042 1082 3.1E-4 T 29-03-2018 IPR006530 YD repeat THSYN_RS17030 5c6e78b49a41bcb5499412715ca98d89 2058 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1503 1536 9.9E-6 T 29-03-2018 IPR006530 YD repeat THSYN_RS17030 5c6e78b49a41bcb5499412715ca98d89 2058 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 937 975 8.1E-6 T 29-03-2018 IPR006530 YD repeat THSYN_RS17030 5c6e78b49a41bcb5499412715ca98d89 2058 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1783 1855 4.3E-24 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 THSYN_RS07450 098f847d85ae606cd718f566e34149b1 70 Gene3D G3DSA:3.30.2390.10 1 69 4.0E-20 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS07450 098f847d85ae606cd718f566e34149b1 70 SUPERFAMILY SSF143100 1 61 5.1E-22 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS07450 098f847d85ae606cd718f566e34149b1 70 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 62 1.3E-14 T 29-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system THSYN_RS10350 9bb841cbfdc8d1c724fb50019712c48a 233 Pfam PF04231 Endonuclease I 51 228 1.4E-25 T 29-03-2018 IPR007346 Endonuclease I GO:0004518 THSYN_RS10350 9bb841cbfdc8d1c724fb50019712c48a 233 SUPERFAMILY SSF54060 14 229 1.09E-57 T 29-03-2018 THSYN_RS05405 f6d306e47615c271af3016a053dc882e 165 SUPERFAMILY SSF55729 7 151 3.49E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS05405 f6d306e47615c271af3016a053dc882e 165 Gene3D G3DSA:3.40.630.30 2 158 4.7E-24 T 29-03-2018 THSYN_RS05405 f6d306e47615c271af3016a053dc882e 165 Pfam PF00583 Acetyltransferase (GNAT) family 45 143 8.9E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS28185 513afdcc60dcbce1e9ec86df94f5e61e 155 SUPERFAMILY SSF46689 1 71 1.09E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS28185 513afdcc60dcbce1e9ec86df94f5e61e 155 Gene3D G3DSA:1.10.10.10 7 71 7.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS28185 513afdcc60dcbce1e9ec86df94f5e61e 155 Pfam PF04255 Protein of unknown function (DUF433) 7 62 2.0E-21 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS01785 3ee00d919726a3280366183c23d22bee 90 Gene3D G3DSA:1.10.260.40 18 83 6.1E-10 T 29-03-2018 THSYN_RS01785 3ee00d919726a3280366183c23d22bee 90 SUPERFAMILY SSF47413 23 82 2.82E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS01785 3ee00d919726a3280366183c23d22bee 90 Pfam PF13744 Helix-turn-helix domain 16 82 3.4E-23 T 29-03-2018 THSYN_RS28395 e4ba5e9406131238cad3f3c2cd470880 206 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 10 199 23.053 T 29-03-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 THSYN_RS28395 e4ba5e9406131238cad3f3c2cd470880 206 Pfam PF01794 Ferric reductase like transmembrane component 54 167 1.7E-19 T 29-03-2018 IPR013130 Ferric reductase transmembrane component-like domain THSYN_RS10475 4f5f03199cd128cf823ececdd7da047f 70 SUPERFAMILY SSF64438 1 39 2.29E-5 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic THSYN_RS10475 4f5f03199cd128cf823ececdd7da047f 70 Pfam PF03975 CheD chemotactic sensory transduction 1 34 4.9E-6 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 THSYN_RS00960 a4118b4f9fda2a1faa08eaa3ab05578d 313 Gene3D G3DSA:3.30.870.10 6 171 1.4E-6 T 29-03-2018 THSYN_RS00960 a4118b4f9fda2a1faa08eaa3ab05578d 313 SUPERFAMILY SSF56024 11 117 5.89E-8 T 29-03-2018 THSYN_RS30490 33f806143f2ab2f81e58b09597ed5490 115 Gene3D G3DSA:1.10.4000.10 11 86 1.9E-9 T 29-03-2018 THSYN_RS30490 33f806143f2ab2f81e58b09597ed5490 115 SUPERFAMILY SSF63592 12 84 7.19E-7 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 THSYN_RS26175 e45450dd26a79deed0c397e1ff313d59 162 Gene3D G3DSA:3.40.50.1010 3 142 9.8E-12 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS26175 e45450dd26a79deed0c397e1ff313d59 162 SUPERFAMILY SSF88723 1 127 4.91E-8 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS18470 aa41926c3872ff78b1fe0b6db4b2edd8 103 Pfam PF03334 Na+/H+ antiporter subunit 12 89 5.2E-22 T 29-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 THSYN_RS13530 0a028dd0f4673f18c8457d1b4f05e0fc 1084 Pfam PF04465 Protein of unknown function (DUF499) 159 428 1.0E-24 T 29-03-2018 IPR007555 Protein of unknown function DUF499 THSYN_RS28350 813f83415599420acf9202b041d9a757 635 Gene3D G3DSA:3.40.50.1820 285 563 4.1E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS28350 813f83415599420acf9202b041d9a757 635 SUPERFAMILY SSF53474 268 554 3.21E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS28350 813f83415599420acf9202b041d9a757 635 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 141 311 1.6E-59 T 29-03-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 THSYN_RS28350 813f83415599420acf9202b041d9a757 635 Pfam PF12551 Poly-beta-hydroxybutyrate polymerase N terminal 65 104 1.7E-18 T 29-03-2018 IPR022211 Poly-beta-hydroxybutyrate polymerase N-terminal THSYN_RS31990 c0fcdfb18d0f3930854244af10be5aab 166 SUPERFAMILY SSF55729 16 148 1.14E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS31990 c0fcdfb18d0f3930854244af10be5aab 166 Pfam PF13673 Acetyltransferase (GNAT) domain 87 146 9.0E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS31990 c0fcdfb18d0f3930854244af10be5aab 166 Gene3D G3DSA:3.40.630.30 2 147 4.0E-13 T 29-03-2018 THSYN_RS10620 70054e0af3745bb1651b4aaa5e6df142 121 Pfam PF03788 LrgA family 12 105 1.9E-28 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 THSYN_RS09320 3568699312c4e6d47d8759fd4ed529fd 332 SUPERFAMILY SSF88713 33 297 2.5E-12 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS09320 3568699312c4e6d47d8759fd4ed529fd 332 Gene3D G3DSA:3.20.20.370 25 302 9.5E-15 T 29-03-2018 THSYN_RS16870 4924640429067b771b63143c0c7cbf2c 274 Pfam PF02673 Bacitracin resistance protein BacA 10 260 1.1E-84 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 THSYN_RS16870 4924640429067b771b63143c0c7cbf2c 274 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 5 265 17.843 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 THSYN_RS16870 4924640429067b771b63143c0c7cbf2c 274 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 10 258 3.3E-78 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 THSYN_RS30500 346577d882d99e9f5eaac53932e69aeb 324 Gene3D G3DSA:3.40.30.10 128 310 3.9E-10 T 29-03-2018 THSYN_RS30500 346577d882d99e9f5eaac53932e69aeb 324 TIGRFAM TIGR02740 TraF-like: TraF-like protein 28 275 3.5E-80 T 29-03-2018 IPR014111 Type IV conjugative transfer system protein TraF THSYN_RS30500 346577d882d99e9f5eaac53932e69aeb 324 SUPERFAMILY SSF52833 170 263 4.6E-9 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS30500 346577d882d99e9f5eaac53932e69aeb 324 Pfam PF13728 F plasmid transfer operon protein 36 266 7.9E-71 T 29-03-2018 THSYN_RS13480 bd155a43d8bb26617d8e768d4fde4398 274 Gene3D G3DSA:3.50.50.60 115 231 1.2E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS13480 bd155a43d8bb26617d8e768d4fde4398 274 Gene3D G3DSA:3.50.50.60 1 114 5.2E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS13480 bd155a43d8bb26617d8e768d4fde4398 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 8.1E-12 T 29-03-2018 THSYN_RS13480 bd155a43d8bb26617d8e768d4fde4398 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 8.1E-12 T 29-03-2018 THSYN_RS13480 bd155a43d8bb26617d8e768d4fde4398 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 8.1E-12 T 29-03-2018 THSYN_RS13480 bd155a43d8bb26617d8e768d4fde4398 274 Gene3D G3DSA:3.40.50.150 232 274 5.8E-4 T 29-03-2018 THSYN_RS13480 bd155a43d8bb26617d8e768d4fde4398 274 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.8E-12 T 29-03-2018 THSYN_RS13480 bd155a43d8bb26617d8e768d4fde4398 274 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 1.8E-12 T 29-03-2018 THSYN_RS13480 bd155a43d8bb26617d8e768d4fde4398 274 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 236 1.9E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS13480 bd155a43d8bb26617d8e768d4fde4398 274 SUPERFAMILY SSF51905 2 195 1.88E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS29140 974fc681ba9d64268bb5c03afef55719 290 Pfam PF01555 DNA methylase 44 266 3.7E-53 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THSYN_RS29140 974fc681ba9d64268bb5c03afef55719 290 SUPERFAMILY SSF53335 22 280 5.26E-65 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS29140 974fc681ba9d64268bb5c03afef55719 290 Gene3D G3DSA:3.40.50.150 21 286 2.2E-64 T 29-03-2018 THSYN_RS29140 974fc681ba9d64268bb5c03afef55719 290 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 48 53 - T 29-03-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS29140 974fc681ba9d64268bb5c03afef55719 290 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 75 95 4.4E-37 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS29140 974fc681ba9d64268bb5c03afef55719 290 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 209 226 4.4E-37 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS29140 974fc681ba9d64268bb5c03afef55719 290 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 228 246 4.4E-37 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS29140 974fc681ba9d64268bb5c03afef55719 290 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 251 271 4.4E-37 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS29140 974fc681ba9d64268bb5c03afef55719 290 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 43 57 4.4E-37 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THSYN_RS17735 63f4d7ab870c8b8d2359c64405f1fdcf 199 Pfam PF07589 PEP-CTERM motif 159 181 4.5E-6 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS17735 63f4d7ab870c8b8d2359c64405f1fdcf 199 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 160 181 6.6E-5 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS05035 f692e4df3eccb957cccac8c107fbe8e8 187 SUPERFAMILY SSF159941 6 179 2.48E-64 T 29-03-2018 IPR024047 Protein MM3350-like domain THSYN_RS05035 f692e4df3eccb957cccac8c107fbe8e8 187 Gene3D G3DSA:3.10.290.30 1 180 5.1E-66 T 29-03-2018 IPR024047 Protein MM3350-like domain THSYN_RS05035 f692e4df3eccb957cccac8c107fbe8e8 187 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 8 177 1.1E-65 T 29-03-2018 IPR012912 Plasmid pRiA4b, Orf3 THSYN_RS10700 fe5281f86203f40036946d36f845ef99 175 SUPERFAMILY SSF81301 25 153 4.58E-15 T 29-03-2018 THSYN_RS17135 3c07e2cd06fcf94e99d960c9d70fafae 167 Gene3D G3DSA:3.40.50.1010 1 155 3.2E-4 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS23080 f203919f59560f0a0692769ede375008 77 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 6 40 2.0E-7 T 29-03-2018 THSYN_RS23080 f203919f59560f0a0692769ede375008 77 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 48 3.8E-11 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS23080 f203919f59560f0a0692769ede375008 77 Gene3D G3DSA:3.40.1620.10 1 59 9.6E-15 T 29-03-2018 THSYN_RS23080 f203919f59560f0a0692769ede375008 77 SUPERFAMILY SSF143120 1 42 4.05E-9 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS02540 3e5717827f595b8e673aca6111660d08 241 Pfam PF02390 Putative methyltransferase 66 234 1.6E-52 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 THSYN_RS02540 3e5717827f595b8e673aca6111660d08 241 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 57 239 3.4E-53 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 THSYN_RS02540 3e5717827f595b8e673aca6111660d08 241 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 25 241 30.179 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 THSYN_RS02540 3e5717827f595b8e673aca6111660d08 241 SUPERFAMILY SSF53335 16 240 1.35E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02540 3e5717827f595b8e673aca6111660d08 241 Gene3D G3DSA:3.40.50.150 31 241 1.7E-28 T 29-03-2018 THSYN_RS31905 a70ff27a548494423c49f98d5124fe08 74 Pfam PF11455 Protein of unknown function (DUF3018) 8 72 1.9E-28 T 29-03-2018 IPR021558 Protein of unknown function DUF3018 THSYN_RS05885 d04ba417b5e883e0714a2fd2ad7fd9f2 70 Gene3D G3DSA:3.30.920.30 1 65 1.5E-15 T 29-03-2018 THSYN_RS05885 d04ba417b5e883e0714a2fd2ad7fd9f2 70 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 26 65 9.1E-10 T 29-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 THSYN_RS05885 d04ba417b5e883e0714a2fd2ad7fd9f2 70 SUPERFAMILY SSF54786 25 69 1.29E-7 T 29-03-2018 THSYN_RS29470 6e035ef475f0f661c0e2d85ae3f5256b 456 Pfam PF01051 Initiator Replication protein 34 245 1.5E-22 T 29-03-2018 IPR000525 Initiator Rep protein GO:0003887|GO:0005727|GO:0006270 THSYN_RS29470 6e035ef475f0f661c0e2d85ae3f5256b 456 Gene3D G3DSA:1.10.10.10 20 157 7.1E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS29470 6e035ef475f0f661c0e2d85ae3f5256b 456 SUPERFAMILY SSF46785 150 249 1.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS29470 6e035ef475f0f661c0e2d85ae3f5256b 456 Gene3D G3DSA:1.10.10.10 163 255 1.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS28645 04d4dbba96debab937e096dbf4c9d70e 366 Gene3D G3DSA:3.40.390.10 147 338 2.3E-6 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 THSYN_RS28645 04d4dbba96debab937e096dbf4c9d70e 366 Gene3D G3DSA:1.10.101.10 36 113 4.1E-8 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS28645 04d4dbba96debab937e096dbf4c9d70e 366 Pfam PF01471 Putative peptidoglycan binding domain 44 101 4.4E-6 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS15155 e54da5710b8bf50c16f8c1906631328e 80 SMART SM00966 6 51 8.1E-7 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS15155 e54da5710b8bf50c16f8c1906631328e 80 Gene3D G3DSA:2.10.260.10 1 80 1.3E-18 T 29-03-2018 THSYN_RS15155 e54da5710b8bf50c16f8c1906631328e 80 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 49 1.0E-7 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THSYN_RS15155 e54da5710b8bf50c16f8c1906631328e 80 SUPERFAMILY SSF89447 1 72 4.19E-17 T 29-03-2018 THSYN_RS22535 f42e082973633b57d78540d09084fa96 105 SUPERFAMILY SSF46785 42 93 2.52E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS22535 f42e082973633b57d78540d09084fa96 105 Gene3D G3DSA:1.10.10.10 9 97 6.3E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS22535 f42e082973633b57d78540d09084fa96 105 Pfam PF12802 MarR family 43 94 1.4E-6 T 29-03-2018 THSYN_RS32260 5ca823672ff4e7b54a713e4d6c9c5abc 173 PRINTS PR01415 Ankyrin repeat signature 122 136 6.2E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS32260 5ca823672ff4e7b54a713e4d6c9c5abc 173 PRINTS PR01415 Ankyrin repeat signature 74 89 6.2E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS32260 5ca823672ff4e7b54a713e4d6c9c5abc 173 SUPERFAMILY SSF48403 65 160 1.76E-23 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS32260 5ca823672ff4e7b54a713e4d6c9c5abc 173 SMART SM00248 73 102 0.001 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS32260 5ca823672ff4e7b54a713e4d6c9c5abc 173 SMART SM00248 106 135 0.32 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 THSYN_RS32260 5ca823672ff4e7b54a713e4d6c9c5abc 173 Pfam PF12796 Ankyrin repeats (3 copies) 66 137 2.4E-10 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS32260 5ca823672ff4e7b54a713e4d6c9c5abc 173 Gene3D G3DSA:1.25.40.20 28 173 6.9E-27 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain THSYN_RS30295 d2f36c10e0a1f6d75193464695df89ce 147 Pfam PF07030 Protein of unknown function (DUF1320) 7 122 4.5E-27 T 29-03-2018 IPR009752 Bacteriophage Mu, Gp36 THSYN_RS23305 9a1006f9dfbd10c3b5e39b94cca9e168 357 Pfam PF01758 Sodium Bile acid symporter family 69 244 4.9E-30 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 THSYN_RS24130 7eb638b1d129f16db64b123f8cccb678 77 SUPERFAMILY SSF141694 1 40 6.54E-7 T 29-03-2018 THSYN_RS24130 7eb638b1d129f16db64b123f8cccb678 77 Gene3D G3DSA:4.10.1150.10 1 69 1.7E-18 T 29-03-2018 IPR024069 AF2212-like domain THSYN_RS24130 7eb638b1d129f16db64b123f8cccb678 77 Pfam PF01954 Protein of unknown function DUF104 1 34 6.0E-5 T 29-03-2018 IPR008203 Uncharacterised protein family UPF0165 THSYN_RS24290 6226dd8eb9a148b5069a5b33280cc5fa 273 Pfam PF06966 Protein of unknown function (DUF1295) 22 249 3.7E-70 T 29-03-2018 IPR010721 Protein of unknown function DUF1295 THSYN_RS22870 b5ca1e921100dd62b6172854da150d49 145 Pfam PF01724 Domain of unknown function DUF29 6 142 3.4E-45 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS08845 7adcd9270ec002fe5c2edbf7106981d0 477 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 13 442 2.2E-113 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THSYN_RS08845 7adcd9270ec002fe5c2edbf7106981d0 477 SUPERFAMILY SSF81442 9 464 2.35E-118 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THSYN_RS08845 7adcd9270ec002fe5c2edbf7106981d0 477 Gene3D G3DSA:1.20.210.10 6 472 5.5E-93 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THSYN_RS08845 7adcd9270ec002fe5c2edbf7106981d0 477 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 7 461 2.2E-203 T 29-03-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 THSYN_RS08845 7adcd9270ec002fe5c2edbf7106981d0 477 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 203 258 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THSYN_RS14510 cdbdb69ca05aa1aeee705cb097958b7a 225 Pfam PF04754 Putative transposase, YhgA-like 3 105 4.6E-17 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS03275 417d63e160f82706de5f0c2628aaa258 209 SUPERFAMILY SSF52374 1 209 2.69E-43 T 29-03-2018 THSYN_RS03275 417d63e160f82706de5f0c2628aaa258 209 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 209 25.357 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 THSYN_RS03275 417d63e160f82706de5f0c2628aaa258 209 Pfam PF01467 Cytidylyltransferase-like 5 182 1.8E-24 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THSYN_RS03275 417d63e160f82706de5f0c2628aaa258 209 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 4 208 1.2E-41 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 THSYN_RS03275 417d63e160f82706de5f0c2628aaa258 209 Gene3D G3DSA:3.40.50.620 1 209 2.1E-43 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS03315 385f4a67fcefe49077e360f743f8398a 601 Gene3D G3DSA:3.40.50.300 6 213 6.1E-14 T 29-03-2018 THSYN_RS03315 385f4a67fcefe49077e360f743f8398a 601 Pfam PF01863 Protein of unknown function DUF45 390 591 4.1E-56 T 29-03-2018 IPR002725 Protein of unknown function DUF45 THSYN_RS03315 385f4a67fcefe49077e360f743f8398a 601 SUPERFAMILY SSF52540 96 170 2.75E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03315 385f4a67fcefe49077e360f743f8398a 601 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 98 167 1.4E-14 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS19420 1bb0d997fed4ed7c145e5c50f6cd83c2 219 Pfam PF01930 Domain of unknown function DUF83 19 194 2.0E-27 T 29-03-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 THSYN_RS19420 1bb0d997fed4ed7c145e5c50f6cd83c2 219 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 18 196 7.5E-38 T 29-03-2018 IPR013343 CRISPR-associated protein Cas4 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 5.1E-95 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 5.1E-95 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 5.1E-95 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 5.1E-95 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 5.1E-95 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 5.1E-95 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 5.1E-95 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 5.1E-95 T 29-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 643 3.8E-229 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 Pfam PF01578 Cytochrome C assembly protein 89 295 3.8E-55 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 640 7.8E-124 T 29-03-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 633 646 1.3E-59 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 1.3E-59 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 1.3E-59 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 1.3E-59 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 1.3E-59 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 1.3E-59 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22565 267f1ba2407110b3afc26624e458c450 660 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 1.3E-59 T 29-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS12615 f1fea2220214d239c998e816786f972a 416 Pfam PF12704 MacB-like periplasmic core domain 27 213 1.1E-18 T 29-03-2018 IPR025857 MacB-like periplasmic core domain THSYN_RS12615 f1fea2220214d239c998e816786f972a 416 Pfam PF02687 FtsX-like permease family 303 409 5.8E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THSYN_RS12615 f1fea2220214d239c998e816786f972a 416 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 416 9.7E-154 T 29-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 THSYN_RS10725 2b3fe8a93f2921807049570070dbf4a6 94 Gene3D G3DSA:3.30.1190.10 53 84 5.2E-5 T 29-03-2018 THSYN_RS10725 2b3fe8a93f2921807049570070dbf4a6 94 SUPERFAMILY SSF47413 37 83 2.35E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS10725 2b3fe8a93f2921807049570070dbf4a6 94 Gene3D G3DSA:1.10.10.60 17 52 1.1E-7 T 29-03-2018 THSYN_RS10725 2b3fe8a93f2921807049570070dbf4a6 94 Pfam PF13560 Helix-turn-helix domain 37 73 4.6E-8 T 29-03-2018 THSYN_RS10725 2b3fe8a93f2921807049570070dbf4a6 94 SMART SM00530 34 87 0.0028 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS15310 11707cd2a8001d51bba0c43d259529b8 537 Gene3D G3DSA:1.20.1250.20 213 404 6.9E-16 T 29-03-2018 THSYN_RS15310 11707cd2a8001d51bba0c43d259529b8 537 Pfam PF05977 Transmembrane secretion effector 10 529 2.7E-171 T 29-03-2018 IPR010290 Transmembrane secretion effector THSYN_RS15310 11707cd2a8001d51bba0c43d259529b8 537 Gene3D G3DSA:1.20.1250.20 9 206 5.4E-21 T 29-03-2018 THSYN_RS15310 11707cd2a8001d51bba0c43d259529b8 537 SUPERFAMILY SSF103473 16 403 2.22E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS24365 8a773d8e40081562fec558c0f6ca5be9 160 Gene3D G3DSA:3.40.250.10 2 132 5.9E-24 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS24365 8a773d8e40081562fec558c0f6ca5be9 160 SMART SM00450 19 124 3.1E-20 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS24365 8a773d8e40081562fec558c0f6ca5be9 160 SUPERFAMILY SSF52821 12 129 1.07E-28 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS24365 8a773d8e40081562fec558c0f6ca5be9 160 Pfam PF00581 Rhodanese-like domain 24 120 4.2E-13 T 29-03-2018 IPR001763 Rhodanese-like domain THSYN_RS01260 855f4147fc9bc5815ee8ec3a15f27d7c 691 Pfam PF04922 DIE2/ALG10 family 341 651 2.0E-15 T 29-03-2018 IPR016900 Alpha-2-glucosyltransferase Alg10 GO:0004583|GO:0005789|GO:0006488 KEGG: 00500+2.4.1.25|KEGG: 00510+2.4.1.256|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-446193 THSYN_RS32575 f6c5b5503657a6037f1aff9cb0d352b6 310 SUPERFAMILY SSF51695 19 308 5.68E-65 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 THSYN_RS32575 f6c5b5503657a6037f1aff9cb0d352b6 310 Gene3D G3DSA:3.20.20.190 12 310 1.2E-59 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 THSYN_RS32575 f6c5b5503657a6037f1aff9cb0d352b6 310 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 23 302 1.3E-39 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 THSYN_RS01000 aa07be5402dbde287976975e4ce5e83a 69 Gene3D G3DSA:1.20.5.1000 3 69 6.3E-6 T 29-03-2018 THSYN_RS01000 aa07be5402dbde287976975e4ce5e83a 69 TIGRFAM TIGR02449 TIGR02449: TIGR02449 family protein 8 67 1.5E-21 T 29-03-2018 IPR012662 Conserved hypothetical protein CHP02449 THSYN_RS21605 93036092259b44dc1975259b8b4354ad 315 Gene3D G3DSA:1.10.357.10 185 305 0.0043 T 29-03-2018 THSYN_RS21605 93036092259b44dc1975259b8b4354ad 315 Pfam PF04754 Putative transposase, YhgA-like 6 206 1.9E-49 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS24185 e3ae6018accfdae389ac18c6595d9e96 144 Pfam PF06146 Phosphate-starvation-inducible E 57 123 2.1E-15 T 29-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like THSYN_RS06285 ca8ba89b40d9581180ef4f42bb13cc4b 142 Gene3D G3DSA:3.10.129.10 1 133 1.8E-37 T 29-03-2018 THSYN_RS06285 ca8ba89b40d9581180ef4f42bb13cc4b 142 SUPERFAMILY SSF54637 4 133 2.14E-37 T 29-03-2018 IPR029069 HotDog domain THSYN_RS06285 ca8ba89b40d9581180ef4f42bb13cc4b 142 Pfam PF01575 MaoC like domain 13 115 1.3E-19 T 29-03-2018 IPR002539 MaoC-like domain THSYN_RS22945 c25ed046feffcdf27a2a5fdcbc2ebdfb 243 SMART SM00910 123 227 8.2E-14 T 29-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 THSYN_RS22945 c25ed046feffcdf27a2a5fdcbc2ebdfb 243 Pfam PF08797 HIRAN domain 126 217 4.3E-8 T 29-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 THSYN_RS07495 9324856ae65e0dd594045b3f3b8369ec 197 SMART SM00834 1 43 1.1E-5 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain THSYN_RS07495 9324856ae65e0dd594045b3f3b8369ec 197 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 49 2.1E-9 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain THSYN_RS23575 4d8b8c123c3823b0cbbb4abcd9250c45 306 Gene3D G3DSA:3.30.470.20 156 273 3.5E-10 T 29-03-2018 THSYN_RS23575 4d8b8c123c3823b0cbbb4abcd9250c45 306 SUPERFAMILY SSF56059 100 266 5.3E-17 T 29-03-2018 THSYN_RS23575 4d8b8c123c3823b0cbbb4abcd9250c45 306 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 131 221 9.3E-6 T 29-03-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 THSYN_RS27980 4feef00d1a2e44132ac8a012f7459cfe 1513 Gene3D G3DSA:3.40.50.410 65 777 5.5E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS27980 4feef00d1a2e44132ac8a012f7459cfe 1513 Pfam PF05567 Neisseria PilC beta-propeller domain 926 1321 6.4E-47 T 29-03-2018 IPR008707 PilC beta-propeller domain THSYN_RS20630 b0152d14a3d5253d444434589410e175 568 Pfam PF01609 Transposase DDE domain 189 463 2.6E-15 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS20630 b0152d14a3d5253d444434589410e175 568 Gene3D G3DSA:3.90.350.10 147 446 4.4E-36 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS20630 b0152d14a3d5253d444434589410e175 568 SUPERFAMILY SSF53098 399 470 5.61E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS20630 b0152d14a3d5253d444434589410e175 568 SUPERFAMILY SSF53098 355 372 5.61E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS31685 c3babbde219c159ce042b596a007a870 1245 Pfam PF11965 Domain of unknown function (DUF3479) 19 181 5.9E-51 T 29-03-2018 IPR022571 Magnesium chelatase, subunit H, N-terminal GO:0016851 KEGG: 00860+6.6.1.1|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS31685 c3babbde219c159ce042b596a007a870 1245 Pfam PF02514 CobN/Magnesium Chelatase 185 1221 0.0 T 29-03-2018 IPR003672 CobN/magnesium chelatase GO:0009058 THSYN_RS31685 c3babbde219c159ce042b596a007a870 1245 TIGRFAM TIGR02025 BchH: magnesium chelatase, H subunit 18 777 9.0E-278 T 29-03-2018 IPR011771 Magnesium-chelatase, subunit H GO:0015995|GO:0016851 KEGG: 00860+6.6.1.1|MetaCyc: PWY-5531|MetaCyc: PWY-7159 THSYN_RS00345 a73c93302aba2a627e293fd2e29a831c 88 Pfam PF04380 Membrane fusogenic activity 1 77 1.1E-27 T 29-03-2018 IPR007475 Membrane fusogenic activity THSYN_RS17175 0219538ef5a6ed0e89b002fd9a253e92 727 Pfam PF00271 Helicase conserved C-terminal domain 382 495 3.4E-8 T 29-03-2018 IPR001650 Helicase, C-terminal THSYN_RS17175 0219538ef5a6ed0e89b002fd9a253e92 727 Gene3D G3DSA:3.40.50.300 366 517 2.3E-12 T 29-03-2018 THSYN_RS17175 0219538ef5a6ed0e89b002fd9a253e92 727 SUPERFAMILY SSF52540 248 301 4.18E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17175 0219538ef5a6ed0e89b002fd9a253e92 727 SUPERFAMILY SSF52540 374 509 4.18E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS17175 0219538ef5a6ed0e89b002fd9a253e92 727 Gene3D G3DSA:3.40.50.300 171 257 0.0021 T 29-03-2018 THSYN_RS17175 0219538ef5a6ed0e89b002fd9a253e92 727 Pfam PF04851 Type III restriction enzyme, res subunit 205 245 4.8E-6 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS27050 e952c9b973b2c700973e63fbec8d0001 181 Gene3D G3DSA:3.90.1570.10 1 176 1.7E-27 T 29-03-2018 THSYN_RS27050 e952c9b973b2c700973e63fbec8d0001 181 Pfam PF05685 Putative restriction endonuclease 13 160 2.1E-20 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS27050 e952c9b973b2c700973e63fbec8d0001 181 SUPERFAMILY SSF52980 15 172 1.88E-17 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS08975 224efbe0da8a2f15acd8cd7fdc58b483 283 Pfam PF07357 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) 24 279 1.8E-97 T 29-03-2018 IPR009953 Dinitrogenase reductase ADP-ribosyltransferase GO:0009399|GO:0030701 THSYN_RS15735 807ca46c774e3dac7e2f3b1cebd973f3 247 SUPERFAMILY SSF63848 143 247 5.36E-29 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 THSYN_RS15735 807ca46c774e3dac7e2f3b1cebd973f3 247 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 15 247 24.143 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 THSYN_RS15735 807ca46c774e3dac7e2f3b1cebd973f3 247 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 16 113 4.3E-15 T 29-03-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 THSYN_RS15735 807ca46c774e3dac7e2f3b1cebd973f3 247 Gene3D G3DSA:2.160.20.70 129 247 3.2E-30 T 29-03-2018 THSYN_RS15735 807ca46c774e3dac7e2f3b1cebd973f3 247 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 145 244 1.8E-27 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 THSYN_RS15735 807ca46c774e3dac7e2f3b1cebd973f3 247 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 15 247 1.7E-61 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 THSYN_RS30930 1b96a311f6ac0585a7b1b9bba38ac674 633 Pfam PF05787 Bacterial protein of unknown function (DUF839) 182 588 1.0E-12 T 29-03-2018 IPR008557 Protein of unknown function DUF839 THSYN_RS00310 c49ec3f28634b4f8499bd8de06200806 332 Pfam PF07148 Maltose operon periplasmic protein precursor (MalM) 93 227 5.1E-31 T 29-03-2018 IPR010794 Maltose operon periplasmic GO:0008643|GO:0042597 THSYN_RS03445 b8cba722a663fd5559e16e7b798b5f6c 103 Pfam PF01909 Nucleotidyltransferase domain 13 50 1.1E-8 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS03445 b8cba722a663fd5559e16e7b798b5f6c 103 SUPERFAMILY SSF81301 7 85 4.53E-14 T 29-03-2018 THSYN_RS03445 b8cba722a663fd5559e16e7b798b5f6c 103 Gene3D G3DSA:3.30.460.10 1 98 2.3E-14 T 29-03-2018 THSYN_RS33145 98598533e5923fcaea77ce7e4faedf61 184 Gene3D G3DSA:3.40.50.10070 35 184 1.9E-7 T 29-03-2018 THSYN_RS33145 98598533e5923fcaea77ce7e4faedf61 184 Pfam PF11684 Protein of unknown function (DUF2380) 43 175 5.5E-20 T 29-03-2018 IPR021698 Protein of unknown function DUF2380 THSYN_RS22205 4ef9b45c2dc6124bfd3ff03a3167f9d5 130 SUPERFAMILY SSF51230 4 127 8.82E-44 T 29-03-2018 IPR011053 Single hybrid motif THSYN_RS22205 4ef9b45c2dc6124bfd3ff03a3167f9d5 130 Gene3D G3DSA:2.40.50.100 6 130 4.4E-45 T 29-03-2018 THSYN_RS22205 4ef9b45c2dc6124bfd3ff03a3167f9d5 130 Pfam PF01597 Glycine cleavage H-protein 8 126 2.0E-44 T 29-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate THSYN_RS22205 4ef9b45c2dc6124bfd3ff03a3167f9d5 130 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 127 39.702 T 29-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 THSYN_RS22205 4ef9b45c2dc6124bfd3ff03a3167f9d5 130 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 4 128 1.4E-47 T 29-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 THSYN_RS22205 4ef9b45c2dc6124bfd3ff03a3167f9d5 130 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 THSYN_RS14725 2a1e5f5e94e5b2c8e7fd853143385990 86 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 3 70 5.7E-15 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS14725 2a1e5f5e94e5b2c8e7fd853143385990 86 Gene3D G3DSA:1.10.1220.10 1 41 1.9E-12 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS14725 2a1e5f5e94e5b2c8e7fd853143385990 86 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 1 71 9.6E-25 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS14725 2a1e5f5e94e5b2c8e7fd853143385990 86 SUPERFAMILY SSF47598 1 42 4.78E-10 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS15210 584001a936f353482d3fe2a80faff3d4 238 Gene3D G3DSA:2.40.440.10 87 229 3.5E-4 T 29-03-2018 THSYN_RS04945 a0de198574540e37ae73c58f874d351f 115 Gene3D G3DSA:1.10.10.10 4 104 1.4E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS04945 a0de198574540e37ae73c58f874d351f 115 SUPERFAMILY SSF46785 45 93 2.16E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS23410 fbc0f2d23b193f37db49a183bbef73e1 266 SUPERFAMILY SSF51069 41 261 1.27E-54 T 29-03-2018 IPR001148 Alpha carbonic anhydrase THSYN_RS23410 fbc0f2d23b193f37db49a183bbef73e1 266 Gene3D G3DSA:3.10.200.10 38 262 4.9E-49 T 29-03-2018 IPR001148 Alpha carbonic anhydrase THSYN_RS23410 fbc0f2d23b193f37db49a183bbef73e1 266 Pfam PF00194 Eukaryotic-type carbonic anhydrase 42 262 1.1E-30 T 29-03-2018 IPR001148 Alpha carbonic anhydrase THSYN_RS23410 fbc0f2d23b193f37db49a183bbef73e1 266 SMART SM01057 42 264 2.1E-57 T 29-03-2018 IPR001148 Alpha carbonic anhydrase THSYN_RS09395 bd71369455e7d19aabe4e07c8cae05e6 97 Gene3D G3DSA:1.20.5.1070 13 95 2.4E-6 T 29-03-2018 THSYN_RS15500 01186685ac70e7d2e571c94b8b31198c 453 Gene3D G3DSA:1.10.287.620 6 148 1.8E-4 T 29-03-2018 THSYN_RS21435 8e8287b09ee1948740d148f8268352e5 136 Gene3D G3DSA:1.10.3290.10 18 136 2.8E-14 T 29-03-2018 IPR003812 Fido domain THSYN_RS21435 8e8287b09ee1948740d148f8268352e5 136 Pfam PF13784 Fic/DOC family N-terminal 22 101 8.1E-27 T 29-03-2018 IPR025758 Fic/DOC N-terminal THSYN_RS26350 368cba86a9026edce8c1c54fea502b22 248 Gene3D G3DSA:3.60.60.10 109 247 2.3E-32 T 29-03-2018 THSYN_RS26350 368cba86a9026edce8c1c54fea502b22 248 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 110 238 6.6E-21 T 29-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal THSYN_RS26350 368cba86a9026edce8c1c54fea502b22 248 SUPERFAMILY SSF56235 110 245 3.86E-30 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS17330 034c19a5406aa5398191b27cebcc3feb 1035 SUPERFAMILY SSF55874 20 127 4.3E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS17330 034c19a5406aa5398191b27cebcc3feb 1035 Gene3D G3DSA:3.30.565.10 4 304 1.2E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain THSYN_RS22775 8937320d56881584add85b395e579222 316 Gene3D G3DSA:3.90.550.10 8 231 1.1E-43 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS22775 8937320d56881584add85b395e579222 316 Pfam PF00535 Glycosyl transferase family 2 11 130 9.2E-34 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS22775 8937320d56881584add85b395e579222 316 SUPERFAMILY SSF53448 9 226 3.73E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS11425 4605f02af87c1d386c9a6bf6a23cd0b7 142 SUPERFAMILY SSF88723 4 134 6.45E-33 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS11425 4605f02af87c1d386c9a6bf6a23cd0b7 142 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 132 11.352 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS11425 4605f02af87c1d386c9a6bf6a23cd0b7 142 Gene3D G3DSA:3.40.50.1010 3 141 1.2E-26 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS11425 4605f02af87c1d386c9a6bf6a23cd0b7 142 Pfam PF01850 PIN domain 6 127 2.0E-17 T 29-03-2018 IPR002716 PIN domain THSYN_RS14410 ee12b990eff3dc17fdd4dc51226c3e1a 80 PIRSF PIRSF037031 1 78 2.9E-26 T 29-03-2018 IPR005243 Redox-active disulphide protein 2 THSYN_RS14410 ee12b990eff3dc17fdd4dc51226c3e1a 80 Pfam PF13192 Thioredoxin domain 3 76 1.6E-23 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS14410 ee12b990eff3dc17fdd4dc51226c3e1a 80 Gene3D G3DSA:3.40.30.10 1 77 7.6E-11 T 29-03-2018 THSYN_RS14410 ee12b990eff3dc17fdd4dc51226c3e1a 80 SUPERFAMILY SSF52833 2 76 4.75E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS14835 51cde35d479f0bedb19d75a46784a911 489 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 297 361 3.1E-13 T 29-03-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain THSYN_RS14835 51cde35d479f0bedb19d75a46784a911 489 Pfam PF04326 Putative DNA-binding domain 14 127 2.6E-18 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 THSYN_RS26100 782d805933a7b98ccbc50e46c61495fa 290 Gene3D G3DSA:3.90.1580.10 53 288 2.5E-55 T 29-03-2018 THSYN_RS26100 782d805933a7b98ccbc50e46c61495fa 290 SUPERFAMILY SSF56436 58 284 1.77E-60 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS26100 782d805933a7b98ccbc50e46c61495fa 290 Pfam PF03781 Sulfatase-modifying factor enzyme 1 61 283 5.4E-49 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS14210 5c47cf0b136ac95e3f265a3896aa8c60 100 SMART SM01248 7 88 1.9E-43 T 29-03-2018 IPR011649 KaiB domain GO:0048511 THSYN_RS14210 5c47cf0b136ac95e3f265a3896aa8c60 100 Pfam PF07689 KaiB domain 7 87 5.1E-26 T 29-03-2018 IPR011649 KaiB domain GO:0048511 THSYN_RS14210 5c47cf0b136ac95e3f265a3896aa8c60 100 SUPERFAMILY SSF52833 3 88 2.33E-26 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS14210 5c47cf0b136ac95e3f265a3896aa8c60 100 Gene3D G3DSA:3.40.30.10 3 84 1.4E-14 T 29-03-2018 THSYN_RS03795 3cdfa47e0589359083a90df99edcc807 170 Pfam PF03734 L,D-transpeptidase catalytic domain 32 168 1.3E-15 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 THSYN_RS03795 3cdfa47e0589359083a90df99edcc807 170 Gene3D G3DSA:2.40.440.10 23 169 4.5E-19 T 29-03-2018 THSYN_RS03795 3cdfa47e0589359083a90df99edcc807 170 SUPERFAMILY SSF141523 28 169 3.53E-21 T 29-03-2018 THSYN_RS19525 4b77784383378265723b267392afddac 73 SUPERFAMILY SSF143120 1 43 7.46E-6 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS19525 4b77784383378265723b267392afddac 73 Gene3D G3DSA:3.40.1620.10 1 72 7.1E-9 T 29-03-2018 THSYN_RS19525 4b77784383378265723b267392afddac 73 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 41 2.5E-7 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS12305 d9da6e3db3dbe1eed3ace0005be8e4bc 256 Gene3D G3DSA:3.90.1570.10 14 172 2.5E-26 T 29-03-2018 THSYN_RS12305 d9da6e3db3dbe1eed3ace0005be8e4bc 256 Pfam PF05685 Putative restriction endonuclease 20 135 7.6E-19 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS12305 d9da6e3db3dbe1eed3ace0005be8e4bc 256 SUPERFAMILY SSF52980 13 147 1.18E-13 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS30765 300f696ed00b407df19c908b85989a62 144 Pfam PF09335 SNARE associated Golgi protein 20 137 4.3E-12 T 29-03-2018 IPR032816 SNARE associated Golgi protein THSYN_RS11400 2671cd9904f1fbcdcc19365de38171aa 126 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 100 - T 29-03-2018 IPR010916 TonB box, conserved site THSYN_RS11400 2671cd9904f1fbcdcc19365de38171aa 126 Gene3D G3DSA:2.40.50.200 19 111 3.0E-7 T 29-03-2018 THSYN_RS10120 d15a36e03158a7311e4883bad19f3d01 107 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 6 101 3.1E-10 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THSYN_RS10120 d15a36e03158a7311e4883bad19f3d01 107 Gene3D G3DSA:2.30.30.110 3 103 2.9E-12 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS10120 d15a36e03158a7311e4883bad19f3d01 107 SUPERFAMILY SSF50118 6 104 5.45E-16 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THSYN_RS30715 2e0834674756965626c72eea6ae493f2 545 Gene3D G3DSA:3.50.50.60 8 518 1.2E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS30715 2e0834674756965626c72eea6ae493f2 545 Pfam PF06100 MCRA family 10 513 4.8E-154 T 29-03-2018 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 THSYN_RS30715 2e0834674756965626c72eea6ae493f2 545 SUPERFAMILY SSF51905 17 294 1.84E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THSYN_RS18820 8f0c29c44e6eefd851fe09d03f02d4d0 386 Pfam PF10503 Esterase PHB depolymerase 122 308 1.8E-59 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 THSYN_RS18820 8f0c29c44e6eefd851fe09d03f02d4d0 386 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 124 306 5.8E-42 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 THSYN_RS18820 8f0c29c44e6eefd851fe09d03f02d4d0 386 SUPERFAMILY SSF53474 118 311 1.96E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS18820 8f0c29c44e6eefd851fe09d03f02d4d0 386 SUPERFAMILY SSF53474 339 379 1.96E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS18820 8f0c29c44e6eefd851fe09d03f02d4d0 386 Gene3D G3DSA:3.40.50.1820 90 382 4.6E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS01545 68c3fe1259288896362441b0fdca2c26 297 Pfam PF06629 MltA-interacting protein MipA 55 278 1.1E-31 T 29-03-2018 IPR010583 MltA-interacting MipA THSYN_RS15795 44ccf194b828970fed891e54afe3bf58 320 Pfam PF01715 IPP transferase 47 295 3.4E-75 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 THSYN_RS15795 44ccf194b828970fed891e54afe3bf58 320 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 13 311 28.035 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 THSYN_RS15795 44ccf194b828970fed891e54afe3bf58 320 SUPERFAMILY SSF52540 10 126 2.45E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS15795 44ccf194b828970fed891e54afe3bf58 320 Gene3D G3DSA:1.10.287.890 210 292 5.1E-24 T 29-03-2018 THSYN_RS15795 44ccf194b828970fed891e54afe3bf58 320 Gene3D G3DSA:3.40.50.300 9 195 1.4E-51 T 29-03-2018 THSYN_RS15795 44ccf194b828970fed891e54afe3bf58 320 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 13 301 1.3E-92 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 THSYN_RS02495 818f26fefdca410e57cb8d1dee8a4839 235 Pfam PF11356 Type II secretion system protein C 7 160 2.9E-7 T 29-03-2018 IPR024961 Type II secretion system protein C, N-terminal THSYN_RS30260 bf545c6f73baacd1541734cecadbb7c5 193 Pfam PF05069 Phage virion morphogenesis family 29 103 5.3E-13 T 29-03-2018 IPR006522 Phage virion morphogensis protein THSYN_RS30260 bf545c6f73baacd1541734cecadbb7c5 193 Pfam PF05069 Phage virion morphogenesis family 107 189 1.0E-13 T 29-03-2018 IPR006522 Phage virion morphogensis protein THSYN_RS30260 bf545c6f73baacd1541734cecadbb7c5 193 TIGRFAM TIGR01635 tail_comp_S: phage virion morphogenesis protein 29 189 3.6E-13 T 29-03-2018 IPR006522 Phage virion morphogensis protein THSYN_RS23065 c5750add8c1b161a1ad7450a7ebad88b 118 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 14 108 5.0E-23 T 29-03-2018 IPR009241 Toxin HigB-like THSYN_RS23065 c5750add8c1b161a1ad7450a7ebad88b 118 Gene3D G3DSA:3.30.2310.20 1 98 9.6E-7 T 29-03-2018 THSYN_RS18320 44ac3cafe83ae3c846054dbfcde4c48a 227 Gene3D G3DSA:3.40.50.410 3 180 3.1E-24 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS18320 44ac3cafe83ae3c846054dbfcde4c48a 227 SMART SM00327 19 197 2.2E-15 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS18320 44ac3cafe83ae3c846054dbfcde4c48a 227 SUPERFAMILY SSF53300 21 175 2.82E-23 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS18320 44ac3cafe83ae3c846054dbfcde4c48a 227 PIRSF PIRSF020634 17 223 9.3E-73 T 29-03-2018 IPR011392 Tellurite resistance, TerY THSYN_RS18320 44ac3cafe83ae3c846054dbfcde4c48a 227 Pfam PF00092 von Willebrand factor type A domain 23 172 3.2E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS02725 3a753940535e224d7139a246cea40d3e 731 Gene3D G3DSA:3.40.50.150 7 617 9.6E-31 T 29-03-2018 THSYN_RS02725 3a753940535e224d7139a246cea40d3e 731 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 477 483 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THSYN_RS02725 3a753940535e224d7139a246cea40d3e 731 SUPERFAMILY SSF53335 59 111 9.03E-12 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02725 3a753940535e224d7139a246cea40d3e 731 SUPERFAMILY SSF53335 452 483 9.03E-12 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02725 3a753940535e224d7139a246cea40d3e 731 SUPERFAMILY SSF53335 533 573 9.03E-12 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS12395 d4a654936625fc8f432690a0b9b4bc69 151 Gene3D G3DSA:1.20.120.10 85 127 1.5E-4 T 29-03-2018 THSYN_RS12395 d4a654936625fc8f432690a0b9b4bc69 151 SUPERFAMILY SSF47175 89 126 1.91E-5 T 29-03-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 THSYN_RS11850 d3b515b10c42a110ca3f43115b41969b 423 Pfam PF03600 Citrate transporter 23 365 1.1E-32 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 THSYN_RS11850 d3b515b10c42a110ca3f43115b41969b 423 PRINTS PR00758 Arsenical pump membrane protein signature 282 306 6.0E-10 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THSYN_RS11850 d3b515b10c42a110ca3f43115b41969b 423 PRINTS PR00758 Arsenical pump membrane protein signature 392 416 6.0E-10 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THSYN_RS11850 d3b515b10c42a110ca3f43115b41969b 423 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 6.0E-10 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THSYN_RS26125 84884789aac23f02b991d184cf34de8d 144 SUPERFAMILY SSF55961 4 143 6.98E-31 T 29-03-2018 THSYN_RS26125 84884789aac23f02b991d184cf34de8d 144 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 134 1.5E-26 T 29-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 THSYN_RS26125 84884789aac23f02b991d184cf34de8d 144 Gene3D G3DSA:3.30.530.20 1 144 1.7E-27 T 29-03-2018 IPR023393 START-like domain THSYN_RS24270 0ae70f461f0fed2657eebbb76181abf2 228 Pfam PF13759 Putative 2OG-Fe(II) oxygenase 108 207 1.2E-19 T 29-03-2018 IPR012668 Conserved hypothetical protein CHP02466 THSYN_RS24270 0ae70f461f0fed2657eebbb76181abf2 228 Gene3D G3DSA:2.60.120.620 27 216 4.4E-22 T 29-03-2018 THSYN_RS22390 6af9189f1e349221e6180b4b8084ab4b 319 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 128 309 2.0E-23 T 29-03-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein THSYN_RS07500 9b83392d22d504a26fa2426a87b178a5 1164 Gene3D G3DSA:2.60.120.260 870 1013 2.7E-6 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS07500 9b83392d22d504a26fa2426a87b178a5 1164 Pfam PF04892 VanZ like family 20 143 1.3E-11 T 29-03-2018 IPR006976 VanZ-like THSYN_RS04665 15183c947341795211aa6534cfd884d6 355 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 213 4.6E-7 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THSYN_RS04665 15183c947341795211aa6534cfd884d6 355 Gene3D G3DSA:3.40.50.720 1 307 1.7E-11 T 29-03-2018 THSYN_RS04665 15183c947341795211aa6534cfd884d6 355 SUPERFAMILY SSF51735 1 300 3.55E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 SUPERFAMILY SSF49299 152 244 5.23E-8 T 29-03-2018 IPR000601 PKD domain THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 Gene3D G3DSA:2.60.40.10 260 337 3.7E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 SUPERFAMILY SSF101898 1095 1297 3.14E-5 T 29-03-2018 THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 Gene3D G3DSA:2.60.40.10 228 259 0.086 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 Gene3D G3DSA:2.60.40.10 147 227 6.5E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 Gene3D G3DSA:2.60.40.10 338 430 2.7E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 SUPERFAMILY SSF49313 247 341 1.53E-5 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 SUPERFAMILY SSF49452 572 643 1.02E-10 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 Pfam PF13620 Carboxypeptidase regulatory-like domain 576 640 2.2E-10 T 29-03-2018 THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 SMART SM00089 359 431 7.0 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 SMART SM00089 277 340 3.7 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 SMART SM00089 164 240 1.0E-4 T 29-03-2018 IPR022409 PKD/Chitinase domain THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 Gene3D G3DSA:2.60.40.1120 576 648 2.8E-10 T 29-03-2018 THSYN_RS13710 b3d71ccf719d62f061f5aa1ef409f47a 1315 SUPERFAMILY SSF49313 344 431 2.35E-7 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 THSYN_RS21035 69645362ae85fb1b99e11a702664fb5a 80 SUPERFAMILY SSF89447 6 69 5.23E-9 T 29-03-2018 THSYN_RS21035 69645362ae85fb1b99e11a702664fb5a 80 Gene3D G3DSA:2.10.260.10 2 71 1.6E-5 T 29-03-2018 THSYN_RS26720 e15d1ce0cf4a95e72c346aed5638e887 156 TIGRFAM TIGR01841 phasin: phasin family protein 62 149 5.9E-15 T 29-03-2018 IPR010127 Phasin, subfamily 1 THSYN_RS26720 e15d1ce0cf4a95e72c346aed5638e887 156 Pfam PF09361 Phasin protein 44 140 1.4E-19 T 29-03-2018 IPR018968 Phasin THSYN_RS21610 d98a21720fd0857d1fbbf0426577d48f 73 SUPERFAMILY SSF143100 6 63 7.06E-6 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS21610 d98a21720fd0857d1fbbf0426577d48f 73 Gene3D G3DSA:3.30.2390.10 5 64 1.8E-4 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS18220 91eb8286aa55cb9c97bb57a53a277f93 98 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 26 70 1.9E-12 T 29-03-2018 IPR022453 Zinc finger, MqsA-type THSYN_RS19130 5a946338f9db019cf9e97e326d9916d3 238 Gene3D G3DSA:3.90.1570.10 45 203 2.6E-17 T 29-03-2018 THSYN_RS19130 5a946338f9db019cf9e97e326d9916d3 238 Pfam PF05685 Putative restriction endonuclease 52 187 5.5E-15 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS19130 5a946338f9db019cf9e97e326d9916d3 238 SUPERFAMILY SSF52980 56 186 6.43E-10 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS02605 c5d382335b939f4a0f6e97e780a810f2 1076 Gene3D G3DSA:3.40.50.150 117 815 6.6E-40 T 29-03-2018 THSYN_RS02605 c5d382335b939f4a0f6e97e780a810f2 1076 SUPERFAMILY SSF53335 156 255 1.54E-14 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02605 c5d382335b939f4a0f6e97e780a810f2 1076 SUPERFAMILY SSF53335 643 676 1.54E-14 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02605 c5d382335b939f4a0f6e97e780a810f2 1076 SUPERFAMILY SSF53335 735 786 1.54E-14 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS02605 c5d382335b939f4a0f6e97e780a810f2 1076 Pfam PF06634 Protein of unknown function (DUF1156) 14 67 7.2E-16 T 29-03-2018 IPR009537 Domain of unknown function DUF1156 THSYN_RS29440 80fe0abcb2903675e3114f8b83bf5f22 399 Pfam PF01385 Probable transposase 173 277 2.6E-28 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 THSYN_RS29440 80fe0abcb2903675e3114f8b83bf5f22 399 Pfam PF07282 Putative transposase DNA-binding domain 291 360 3.7E-22 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal THSYN_RS29440 80fe0abcb2903675e3114f8b83bf5f22 399 Pfam PF12323 Helix-turn-helix domain 1 44 4.3E-14 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain THSYN_RS29440 80fe0abcb2903675e3114f8b83bf5f22 399 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 246 318 5.5E-10 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal THSYN_RS13305 3831fe09a2b3fb5d688e3d49e68361b4 306 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 9 301 1.1E-26 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA THSYN_RS13305 3831fe09a2b3fb5d688e3d49e68361b4 306 Gene3D G3DSA:1.10.10.60 245 301 2.6E-6 T 29-03-2018 THSYN_RS13305 3831fe09a2b3fb5d688e3d49e68361b4 306 Pfam PF12784 PD-(D/E)XK nuclease family transposase 9 125 1.0E-22 T 29-03-2018 THSYN_RS11125 52b172d254ff0d57ce05011069514150 158 Pfam PF01814 Hemerythrin HHE cation binding domain 3 136 1.7E-9 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THSYN_RS11125 52b172d254ff0d57ce05011069514150 158 Gene3D G3DSA:1.20.120.520 1 146 3.3E-9 T 29-03-2018 THSYN_RS09000 e6f1152981279d750c13761fa252a634 208 Pfam PF01810 LysE type translocator 16 196 1.3E-17 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 THSYN_RS17390 348c706069b3435f121e78095d523eef 261 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 48 258 7.8E-34 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 THSYN_RS17390 348c706069b3435f121e78095d523eef 261 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 261 44.543 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 THSYN_RS17390 348c706069b3435f121e78095d523eef 261 Pfam PF02654 Cobalamin-5-phosphate synthase 23 255 8.1E-47 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 THSYN_RS27105 e048e1e832b04965e07c7b08a1b70dcf 176 Pfam PF13527 Acetyltransferase (GNAT) domain 2 127 1.7E-12 T 29-03-2018 THSYN_RS27105 e048e1e832b04965e07c7b08a1b70dcf 176 SUPERFAMILY SSF55729 1 151 3.49E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS27105 e048e1e832b04965e07c7b08a1b70dcf 176 Gene3D G3DSA:3.40.630.30 1 132 8.4E-17 T 29-03-2018 THSYN_RS04420 5bce541300fffa50b420d7e96ad2b162 336 Gene3D G3DSA:3.30.420.10 106 320 1.9E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS29290 6f12b556921978f84a6a1a11fbc0c40f 109 Gene3D G3DSA:3.30.230.10 2 106 1.1E-23 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS29290 6f12b556921978f84a6a1a11fbc0c40f 109 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 90 1.0E-14 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 THSYN_RS29290 6f12b556921978f84a6a1a11fbc0c40f 109 SUPERFAMILY SSF54211 4 101 5.06E-21 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THSYN_RS29290 6f12b556921978f84a6a1a11fbc0c40f 109 Pfam PF00825 Ribonuclease P 5 101 3.0E-23 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 THSYN_RS29290 6f12b556921978f84a6a1a11fbc0c40f 109 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 6 100 5.8E-18 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 THSYN_RS29580 92f7387568d8647b5857603d66ade279 112 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 51 108 1.5E-20 T 29-03-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system THSYN_RS21890 de4b9d4589a4032dae5208d8132a920c 646 Pfam PF12770 CHAT domain 310 643 2.7E-56 T 29-03-2018 IPR024983 CHAT domain THSYN_RS21890 de4b9d4589a4032dae5208d8132a920c 646 Gene3D G3DSA:3.40.50.1460 378 643 2.5E-20 T 29-03-2018 THSYN_RS08000 93004c55cc6bda23b4c3962ddc106ce0 129 SMART SM00530 10 67 1.2E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS08000 93004c55cc6bda23b4c3962ddc106ce0 129 Gene3D G3DSA:1.10.260.40 3 76 7.6E-16 T 29-03-2018 THSYN_RS08000 93004c55cc6bda23b4c3962ddc106ce0 129 SUPERFAMILY SSF47413 2 72 3.38E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS08000 93004c55cc6bda23b4c3962ddc106ce0 129 Pfam PF01381 Helix-turn-helix 11 67 3.7E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS03000 01cf353b7e5b251f2195b35d847b422a 346 Gene3D G3DSA:3.30.1330.40 203 341 3.1E-21 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THSYN_RS03000 01cf353b7e5b251f2195b35d847b422a 346 SUPERFAMILY SSF55298 208 337 1.16E-11 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THSYN_RS04400 f20d86d2f6278585bc0cefb3b818e801 193 Pfam PF13511 Domain of unknown function (DUF4124) 11 59 1.8E-8 T 29-03-2018 IPR025392 Domain of unknown function DUF4124 THSYN_RS25280 43461c94187c001b9603bc82a79d4e31 141 Gene3D G3DSA:3.30.460.10 6 116 3.7E-18 T 29-03-2018 THSYN_RS25280 43461c94187c001b9603bc82a79d4e31 141 SUPERFAMILY SSF81301 19 101 1.23E-12 T 29-03-2018 THSYN_RS25280 43461c94187c001b9603bc82a79d4e31 141 Pfam PF01909 Nucleotidyltransferase domain 31 99 6.1E-7 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS23615 f6d7596750293b682952acbbe158c5f2 218 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 174 196 7.3E-4 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS29720 f2cf69450f137edd436c852405049695 524 Pfam PF08936 Carboxysome Shell Carbonic Anhydrase 58 510 1.2E-205 T 29-03-2018 IPR014074 Carboxysome shell carbonic anhydrase THSYN_RS29720 f2cf69450f137edd436c852405049695 524 TIGRFAM TIGR02701 shell_carb_anhy: carboxysome shell carbonic anhydrase 58 500 9.7E-182 T 29-03-2018 IPR014074 Carboxysome shell carbonic anhydrase THSYN_RS31875 c0c272db7009b4a4cb8b890fcc80ed97 140 Pfam PF01230 HIT domain 15 109 3.3E-25 T 29-03-2018 IPR001310 Histidine triad (HIT) protein THSYN_RS31875 c0c272db7009b4a4cb8b890fcc80ed97 140 PRINTS PR00332 Histidine triad family signature 96 106 4.3E-17 T 29-03-2018 IPR001310 Histidine triad (HIT) protein THSYN_RS31875 c0c272db7009b4a4cb8b890fcc80ed97 140 PRINTS PR00332 Histidine triad family signature 8 24 4.3E-17 T 29-03-2018 IPR001310 Histidine triad (HIT) protein THSYN_RS31875 c0c272db7009b4a4cb8b890fcc80ed97 140 PRINTS PR00332 Histidine triad family signature 29 47 4.3E-17 T 29-03-2018 IPR001310 Histidine triad (HIT) protein THSYN_RS31875 c0c272db7009b4a4cb8b890fcc80ed97 140 SUPERFAMILY SSF54197 6 138 6.03E-39 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 THSYN_RS31875 c0c272db7009b4a4cb8b890fcc80ed97 140 Gene3D G3DSA:3.30.428.10 2 138 9.9E-37 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 THSYN_RS23165 c93e96e2fb44da27c3440600200e01be 265 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 258 4.3E-51 T 29-03-2018 IPR000150 Cof family GO:0016787 THSYN_RS23165 c93e96e2fb44da27c3440600200e01be 265 ProSitePatterns PS01229 Hypothetical cof family signature 2. 210 232 - T 29-03-2018 THSYN_RS23165 c93e96e2fb44da27c3440600200e01be 265 Gene3D G3DSA:3.40.50.1000 1 265 1.4E-33 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS23165 c93e96e2fb44da27c3440600200e01be 265 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 29-03-2018 THSYN_RS23165 c93e96e2fb44da27c3440600200e01be 265 SUPERFAMILY SSF56784 1 262 1.87E-61 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS23165 c93e96e2fb44da27c3440600200e01be 265 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 229 2.3E-23 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 THSYN_RS23165 c93e96e2fb44da27c3440600200e01be 265 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 258 1.5E-56 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS16260 f9e759f88ca7e39d5fdf40456e340cf8 275 SUPERFAMILY SSF52540 3 268 1.86E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16260 f9e759f88ca7e39d5fdf40456e340cf8 275 Pfam PF13469 Sulfotransferase family 6 211 1.9E-15 T 29-03-2018 THSYN_RS16260 f9e759f88ca7e39d5fdf40456e340cf8 275 Gene3D G3DSA:3.40.50.300 1 271 1.1E-23 T 29-03-2018 THSYN_RS15165 0d00c5b3b778a909534d15c641e7dad0 302 Pfam PF05257 CHAP domain 149 249 3.3E-13 T 29-03-2018 IPR007921 CHAP domain THSYN_RS15165 0d00c5b3b778a909534d15c641e7dad0 302 Gene3D G3DSA:3.90.1720.10 135 268 5.8E-4 T 29-03-2018 THSYN_RS15165 0d00c5b3b778a909534d15c641e7dad0 302 SUPERFAMILY SSF54001 97 297 8.83E-37 T 29-03-2018 THSYN_RS02820 aacaf74a2acb01b17586ba9174b658b9 382 SUPERFAMILY SSF52540 49 336 1.05E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02820 aacaf74a2acb01b17586ba9174b658b9 382 Gene3D G3DSA:3.40.50.300 46 316 4.1E-12 T 29-03-2018 THSYN_RS02820 aacaf74a2acb01b17586ba9174b658b9 382 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 49 313 3.9E-28 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS09495 9767ac8d9a2c7b78a6d4d6ad03a405af 180 Pfam PF07209 Protein of unknown function (DUF1415) 7 169 7.3E-63 T 29-03-2018 IPR009858 Protein of unknown function DUF1415 THSYN_RS13090 90df2a40dcb86a52e5e8fa34c155b786 192 Pfam PF05656 Protein of unknown function (DUF805) 28 148 3.3E-21 T 29-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 THSYN_RS09085 57df01248e3eafe3003158b3bcda892e 145 Pfam PF04930 FUN14 family 55 143 3.7E-13 T 29-03-2018 IPR007014 FUN14 THSYN_RS13245 02ca9e9ecc51552d5b418ee206162c36 194 Gene3D G3DSA:3.40.50.10490 1 194 1.0E-39 T 29-03-2018 THSYN_RS13245 02ca9e9ecc51552d5b418ee206162c36 194 Pfam PF13580 SIS domain 25 146 1.8E-31 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 THSYN_RS13245 02ca9e9ecc51552d5b418ee206162c36 194 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 189 35.37 T 29-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 THSYN_RS13245 02ca9e9ecc51552d5b418ee206162c36 194 SUPERFAMILY SSF53697 2 186 6.67E-54 T 29-03-2018 THSYN_RS09730 d9c7960552dff568785158a4c7104df3 225 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 12 217 3.5E-72 T 29-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 THSYN_RS09730 d9c7960552dff568785158a4c7104df3 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 216 2.0E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS09730 d9c7960552dff568785158a4c7104df3 225 SUPERFAMILY SSF161098 8 215 2.09E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS09730 d9c7960552dff568785158a4c7104df3 225 Gene3D G3DSA:1.10.3720.10 4 219 6.9E-32 T 29-03-2018 THSYN_RS06825 595be1fa155573a6b762135de69b05f1 379 Gene3D G3DSA:3.40.50.2000 6 182 2.9E-19 T 29-03-2018 THSYN_RS06825 595be1fa155573a6b762135de69b05f1 379 SUPERFAMILY SSF53756 5 368 3.45E-75 T 29-03-2018 THSYN_RS06825 595be1fa155573a6b762135de69b05f1 379 Pfam PF13439 Glycosyltransferase Family 4 15 175 4.9E-19 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS06825 595be1fa155573a6b762135de69b05f1 379 Pfam PF00534 Glycosyl transferases group 1 191 345 2.5E-35 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS06825 595be1fa155573a6b762135de69b05f1 379 Gene3D G3DSA:3.40.50.2000 183 352 8.1E-40 T 29-03-2018 THSYN_RS26465 ff0e979b65af8698a228d84eebb41dcb 267 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 6 265 35.005 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 THSYN_RS26465 ff0e979b65af8698a228d84eebb41dcb 267 SUPERFAMILY SSF51366 15 265 1.77E-86 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THSYN_RS26465 ff0e979b65af8698a228d84eebb41dcb 267 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 59 77 - T 29-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 THSYN_RS26465 ff0e979b65af8698a228d84eebb41dcb 267 Pfam PF00218 Indole-3-glycerol phosphate synthase 8 261 6.5E-93 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 THSYN_RS26465 ff0e979b65af8698a228d84eebb41dcb 267 Gene3D G3DSA:3.20.20.70 14 264 4.4E-72 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS13620 0e0af73f3cced850c4b251ee3051357e 864 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 518 847 7.0E-70 T 29-03-2018 IPR007296 Domain of unknown function DUF403 THSYN_RS13620 0e0af73f3cced850c4b251ee3051357e 864 Pfam PF14403 Circularly permuted ATP-grasp type 2 92 468 2.9E-148 T 29-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 THSYN_RS13620 0e0af73f3cced850c4b251ee3051357e 864 SUPERFAMILY SSF56059 337 454 2.33E-21 T 29-03-2018 THSYN_RS13620 0e0af73f3cced850c4b251ee3051357e 864 SUPERFAMILY SSF56059 35 230 2.33E-21 T 29-03-2018 THSYN_RS07370 b50cc046850ee896b9db19eab74e61f1 192 SUPERFAMILY SSF52980 29 159 3.86E-17 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS07370 b50cc046850ee896b9db19eab74e61f1 192 Gene3D G3DSA:3.90.1570.10 4 191 2.4E-32 T 29-03-2018 THSYN_RS07370 b50cc046850ee896b9db19eab74e61f1 192 Pfam PF05685 Putative restriction endonuclease 22 174 2.2E-28 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS33035 edfba57b6afb4274886b840426669607 154 Gene3D G3DSA:3.40.190.10 1 149 1.9E-10 T 29-03-2018 THSYN_RS29350 4acb85b5e01ebc3dde6a3ea2ee6471d4 196 Pfam PF04446 tRNAHis guanylyltransferase 9 88 7.3E-20 T 29-03-2018 IPR024956 tRNAHis guanylyltransferase catalytic domain GO:0000287|GO:0006400|GO:0008193 Reactome: R-HSA-6782315 THSYN_RS29050 8d9458e9e6e0bfda6f658e3d300797c2 404 SUPERFAMILY SSF53756 19 400 1.75E-17 T 29-03-2018 THSYN_RS29050 8d9458e9e6e0bfda6f658e3d300797c2 404 Pfam PF13439 Glycosyltransferase Family 4 27 209 8.2E-7 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS29050 8d9458e9e6e0bfda6f658e3d300797c2 404 Gene3D G3DSA:3.40.50.2000 21 218 2.6E-7 T 29-03-2018 THSYN_RS29050 8d9458e9e6e0bfda6f658e3d300797c2 404 Gene3D G3DSA:3.40.50.2000 219 393 3.0E-8 T 29-03-2018 THSYN_RS19395 eb06e534c79ddd38de244751b422c0df 330 Pfam PF09709 CRISPR-associated protein (Cas_Csd1) 16 280 1.2E-28 T 29-03-2018 IPR010144 CRISPR-associated protein, Csd1-type THSYN_RS16905 4e2b7db6df218e4c40872380863cde15 104 Hamap MF_02117 N(2)-fixation sustaining protein CowN [cowN]. 13 104 19.635 T 29-03-2018 IPR024899 Nitrogen fixation-sustaining protein CowN GO:0009399 THSYN_RS00450 3def0d5f3ab550f0caa70c3a3c49ba61 112 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 42 95 7.7E-13 T 29-03-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter THSYN_RS00450 3def0d5f3ab550f0caa70c3a3c49ba61 112 TIGRFAM TIGR02230 ATPase_gene1: putative F0F1-ATPase subunit 1 99 8.1E-41 T 29-03-2018 IPR011744 F0F1-ATPase subunit, putative THSYN_RS22575 7ef9124f8a109a924ee2931f30c59c11 163 Pfam PF03918 Cytochrome C biogenesis protein 17 152 1.4E-49 T 29-03-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family THSYN_RS32735 e1002529cc14a63178f476c5000230b9 567 SUPERFAMILY SSF56436 124 332 1.77E-33 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS32735 e1002529cc14a63178f476c5000230b9 567 Pfam PF03781 Sulfatase-modifying factor enzyme 1 123 330 5.1E-27 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS32735 e1002529cc14a63178f476c5000230b9 567 Gene3D G3DSA:3.90.1580.10 118 328 8.9E-30 T 29-03-2018 THSYN_RS32105 d59249f9795de535797098b4cad99aea 398 Pfam PF01139 tRNA-splicing ligase RtcB 28 398 4.9E-138 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 THSYN_RS32105 d59249f9795de535797098b4cad99aea 398 SUPERFAMILY SSF103365 14 398 3.53E-137 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 THSYN_RS00280 f5951c1a3a51d3ca29151097385eab86 143 Pfam PF06155 Protein of unknown function (DUF971) 10 94 3.8E-26 T 29-03-2018 IPR010376 Domain of unknown function DUF971 Reactome: R-HSA-71262 THSYN_RS04510 9ec85147eabf37cbba627705ca8b7450 372 Pfam PF06250 Protein of unknown function (DUF1016) 14 346 2.4E-117 T 29-03-2018 IPR009362 Protein of unknown function DUF1016 THSYN_RS16020 819856540e5e2caec81c8e28579be325 569 Pfam PF01935 Domain of unknown function DUF87 140 422 2.1E-38 T 29-03-2018 IPR002789 Helicase HerA, central domain THSYN_RS16020 819856540e5e2caec81c8e28579be325 569 Gene3D G3DSA:3.40.50.300 124 537 3.7E-31 T 29-03-2018 THSYN_RS16020 819856540e5e2caec81c8e28579be325 569 SUPERFAMILY SSF52540 247 548 7.62E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16020 819856540e5e2caec81c8e28579be325 569 SUPERFAMILY SSF52540 135 211 7.62E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS16480 0f17372a972020102c4da51784e8b995 325 Gene3D G3DSA:1.20.1630.10 4 318 5.4E-41 T 29-03-2018 THSYN_RS16480 0f17372a972020102c4da51784e8b995 325 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 1 321 8.8E-30 T 29-03-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 THSYN_RS17970 9fe24d667e3ff13d1780c092c2ebf817 336 Gene3D G3DSA:3.40.50.1000 53 321 9.3E-15 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS17970 9fe24d667e3ff13d1780c092c2ebf817 336 SUPERFAMILY SSF56784 54 304 1.25E-25 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS17970 9fe24d667e3ff13d1780c092c2ebf817 336 Pfam PF12710 haloacid dehalogenase-like hydrolase 57 261 1.1E-22 T 29-03-2018 THSYN_RS12120 7eba9eccf40cb718d59ad8d860f4b9a7 244 Gene3D G3DSA:3.90.1580.10 64 244 9.0E-55 T 29-03-2018 THSYN_RS12120 7eba9eccf40cb718d59ad8d860f4b9a7 244 Gene3D G3DSA:3.90.1580.10 1 63 2.3E-14 T 29-03-2018 THSYN_RS12120 7eba9eccf40cb718d59ad8d860f4b9a7 244 SUPERFAMILY SSF56436 1 233 2.59E-72 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS12120 7eba9eccf40cb718d59ad8d860f4b9a7 244 Pfam PF03781 Sulfatase-modifying factor enzyme 1 1 233 2.4E-58 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS00705 84403d7a162f58027e0d6b2d8efe17e4 247 Gene3D G3DSA:2.40.160.10 60 239 1.6E-4 T 29-03-2018 THSYN_RS00705 84403d7a162f58027e0d6b2d8efe17e4 247 Pfam PF13557 Putative MetA-pathway of phenol degradation 56 242 7.2E-16 T 29-03-2018 IPR025737 MetA-pathway of phenol degradation, putative THSYN_RS11550 69ffaed5eaef5090c471801ef0250aa0 196 Gene3D G3DSA:3.30.70.270 1 107 8.9E-7 T 29-03-2018 THSYN_RS11550 69ffaed5eaef5090c471801ef0250aa0 196 Pfam PF08388 Group II intron, maturase-specific domain 93 137 7.8E-5 T 29-03-2018 IPR013597 Group II intron, maturase-specific THSYN_RS11550 69ffaed5eaef5090c471801ef0250aa0 196 SUPERFAMILY SSF56672 2 64 2.49E-9 T 29-03-2018 THSYN_RS03985 b02c4ac6b0389ee2844f0d6b0ca77c8e 252 Gene3D G3DSA:3.40.630.30 82 233 1.5E-6 T 29-03-2018 THSYN_RS03985 b02c4ac6b0389ee2844f0d6b0ca77c8e 252 SUPERFAMILY SSF55729 85 240 5.8E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS03985 b02c4ac6b0389ee2844f0d6b0ca77c8e 252 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 113 234 7.3E-39 T 29-03-2018 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 THSYN_RS03985 b02c4ac6b0389ee2844f0d6b0ca77c8e 252 PIRSF PIRSF037208 5 250 1.4E-84 T 29-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 THSYN_RS03985 b02c4ac6b0389ee2844f0d6b0ca77c8e 252 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 21 91 2.3E-20 T 29-03-2018 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 THSYN_RS03985 b02c4ac6b0389ee2844f0d6b0ca77c8e 252 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 7 244 41.708 T 29-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 THSYN_RS31420 3c2f5253b54cdd80136ae62a84b7a280 383 Gene3D G3DSA:1.10.600.10 9 284 1.9E-71 T 29-03-2018 IPR008949 Isoprenoid synthase domain THSYN_RS31420 3c2f5253b54cdd80136ae62a84b7a280 383 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 162 187 - T 29-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 THSYN_RS31420 3c2f5253b54cdd80136ae62a84b7a280 383 SUPERFAMILY SSF48576 15 289 5.9E-72 T 29-03-2018 IPR008949 Isoprenoid synthase domain THSYN_RS31420 3c2f5253b54cdd80136ae62a84b7a280 383 Pfam PF00494 Squalene/phytoene synthase 26 273 7.2E-65 T 29-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 THSYN_RS31420 3c2f5253b54cdd80136ae62a84b7a280 383 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 132 147 - T 29-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 THSYN_RS11465 9fcff243a19f34325785ac26a0f511f8 382 Pfam PF10005 zinc-ribbon domain 4 119 4.9E-24 T 29-03-2018 IPR011201 Zinc-ribbon domain, bacteria THSYN_RS11465 9fcff243a19f34325785ac26a0f511f8 382 Pfam PF15887 Putative zinc-binding metallo-peptidase 125 374 1.6E-108 T 29-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase THSYN_RS11465 9fcff243a19f34325785ac26a0f511f8 382 Gene3D G3DSA:3.40.390.10 158 311 9.4E-15 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 THSYN_RS11465 9fcff243a19f34325785ac26a0f511f8 382 PIRSF PIRSF012641 1 382 1.8E-138 T 29-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase THSYN_RS32525 859373954d44fd5975bee70b9aa9625c 220 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 40 123 2.8E-21 T 29-03-2018 IPR018712 Domain of unknown function DUF2235 THSYN_RS11230 5a7242ff884405c88580082fd420e093 154 Gene3D G3DSA:3.30.2000.10 10 152 3.5E-6 T 29-03-2018 THSYN_RS12135 756b62a47b78479609dec2c89b0120a6 434 Gene3D G3DSA:3.90.350.10 106 352 1.3E-16 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS21770 756b62a47b78479609dec2c89b0120a6 434 Gene3D G3DSA:3.90.350.10 106 352 1.3E-16 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS28410 756b62a47b78479609dec2c89b0120a6 434 Gene3D G3DSA:3.90.350.10 106 352 1.3E-16 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS24870 756b62a47b78479609dec2c89b0120a6 434 Gene3D G3DSA:3.90.350.10 106 352 1.3E-16 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS00520 660ffb8f7482c2d9477f4cde3d04a524 414 Pfam PF13173 AAA domain 23 140 1.5E-22 T 29-03-2018 THSYN_RS00520 660ffb8f7482c2d9477f4cde3d04a524 414 Pfam PF13635 Domain of unknown function (DUF4143) 202 361 9.1E-28 T 29-03-2018 IPR025420 Domain of unknown function DUF4143 THSYN_RS00520 660ffb8f7482c2d9477f4cde3d04a524 414 Gene3D G3DSA:3.40.50.300 21 217 1.5E-9 T 29-03-2018 THSYN_RS00520 660ffb8f7482c2d9477f4cde3d04a524 414 SUPERFAMILY SSF52540 14 209 3.66E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27430 69cb9f0aca80a10b4c0ea214c96296ba 385 SUPERFAMILY SSF52540 160 354 1.14E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27430 69cb9f0aca80a10b4c0ea214c96296ba 385 SUPERFAMILY SSF52540 1 129 1.14E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS27430 69cb9f0aca80a10b4c0ea214c96296ba 385 Gene3D G3DSA:3.40.50.300 1 361 5.0E-24 T 29-03-2018 THSYN_RS27430 69cb9f0aca80a10b4c0ea214c96296ba 385 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 27 327 4.2E-26 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS27430 69cb9f0aca80a10b4c0ea214c96296ba 385 PIRSF PIRSF029347 207 354 5.3E-9 T 29-03-2018 IPR014555 RecF-like THSYN_RS27430 69cb9f0aca80a10b4c0ea214c96296ba 385 PIRSF PIRSF029347 1 189 2.0E-11 T 29-03-2018 IPR014555 RecF-like THSYN_RS02310 d22bb3d33501d66845aa93b70edeee81 162 Gene3D G3DSA:3.30.70.640 1 157 2.3E-68 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 THSYN_RS02310 d22bb3d33501d66845aa93b70edeee81 162 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 1 157 36.099 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 THSYN_RS02310 d22bb3d33501d66845aa93b70edeee81 162 SUPERFAMILY SSF55040 10 154 1.96E-59 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 THSYN_RS02310 d22bb3d33501d66845aa93b70edeee81 162 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 3 151 4.1E-62 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 THSYN_RS02310 d22bb3d33501d66845aa93b70edeee81 162 Pfam PF01967 MoaC family 14 149 5.1E-54 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 THSYN_RS12420 4eda96be1283370f07fce1ce350b98a4 718 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 583 712 3.4E-56 T 29-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 THSYN_RS12420 4eda96be1283370f07fce1ce350b98a4 718 Pfam PF01642 Methylmalonyl-CoA mutase 32 544 4.6E-230 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 THSYN_RS12420 4eda96be1283370f07fce1ce350b98a4 718 Gene3D G3DSA:3.40.50.280 570 713 2.0E-37 T 29-03-2018 THSYN_RS12420 4eda96be1283370f07fce1ce350b98a4 718 Pfam PF02310 B12 binding domain 586 701 9.1E-17 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 THSYN_RS12420 4eda96be1283370f07fce1ce350b98a4 718 Gene3D G3DSA:3.20.20.240 30 546 8.0E-239 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 THSYN_RS12420 4eda96be1283370f07fce1ce350b98a4 718 SUPERFAMILY SSF51703 8 546 2.15E-217 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 THSYN_RS12420 4eda96be1283370f07fce1ce350b98a4 718 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 30 549 7.8E-255 T 29-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 THSYN_RS12420 4eda96be1283370f07fce1ce350b98a4 718 SUPERFAMILY SSF52242 552 710 7.2E-54 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 THSYN_RS29355 66ca07a422cee09ddbee6aae41a8db8c 145 Pfam PF09335 SNARE associated Golgi protein 21 138 3.4E-12 T 29-03-2018 IPR032816 SNARE associated Golgi protein THSYN_RS11030 7b1fe3ca10f4735c9c6c25b89ec624a8 887 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 57 83 0.022 T 29-03-2018 IPR013431 Delta-60 repeat THSYN_RS11030 7b1fe3ca10f4735c9c6c25b89ec624a8 887 Gene3D G3DSA:2.130.10.10 16 467 5.2E-11 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS11030 7b1fe3ca10f4735c9c6c25b89ec624a8 887 SUPERFAMILY SSF50978 25 256 6.1E-10 T 29-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 THSYN_RS11030 7b1fe3ca10f4735c9c6c25b89ec624a8 887 Pfam PF16640 Bacterial Ig-like domain (group 3) 534 616 3.5E-20 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) THSYN_RS11030 7b1fe3ca10f4735c9c6c25b89ec624a8 887 Pfam PF16640 Bacterial Ig-like domain (group 3) 282 365 3.1E-20 T 29-03-2018 IPR032109 Bacterial Ig-like domain (group 3) THSYN_RS31800 739095d89332e13a96fcdca0d741af37 94 Gene3D G3DSA:1.10.1220.10 7 50 1.4E-13 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS31800 739095d89332e13a96fcdca0d741af37 94 Gene3D G3DSA:1.20.890.30 54 89 2.1E-13 T 29-03-2018 THSYN_RS31800 739095d89332e13a96fcdca0d741af37 94 SUPERFAMILY SSF47598 7 84 1.28E-21 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS31800 739095d89332e13a96fcdca0d741af37 94 Pfam PF08681 Protein of unknown function (DUF1778) 10 87 3.7E-25 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 THSYN_RS19635 2d241ecd7c478afd428fa6445d88e460 387 Gene3D G3DSA:3.40.50.2000 2 187 1.2E-19 T 29-03-2018 THSYN_RS19635 2d241ecd7c478afd428fa6445d88e460 387 Gene3D G3DSA:3.40.50.2000 188 363 4.8E-37 T 29-03-2018 THSYN_RS19635 2d241ecd7c478afd428fa6445d88e460 387 Pfam PF13692 Glycosyl transferases group 1 205 344 7.2E-23 T 29-03-2018 THSYN_RS19635 2d241ecd7c478afd428fa6445d88e460 387 SUPERFAMILY SSF53756 5 381 3.72E-67 T 29-03-2018 THSYN_RS19635 2d241ecd7c478afd428fa6445d88e460 387 Pfam PF13579 Glycosyl transferase 4-like domain 18 176 4.6E-14 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS17345 a1a2159431b1c59eba91de59d9496b31 59 Gene3D G3DSA:2.40.70.10 1 58 6.0E-4 T 29-03-2018 IPR021109 Aspartic peptidase domain THSYN_RS17865 c88a957b3d61185049537edf23274160 92 Gene3D G3DSA:3.30.2310.20 2 82 1.1E-10 T 29-03-2018 THSYN_RS17865 c88a957b3d61185049537edf23274160 92 SUPERFAMILY SSF143011 5 79 5.76E-9 T 29-03-2018 IPR035095 Toxin RelE-like domain THSYN_RS21370 ee8ac99ab635af81f68dcacf6b7fe151 204 Gene3D G3DSA:3.30.1950.10 44 104 2.0E-14 T 29-03-2018 THSYN_RS21370 ee8ac99ab635af81f68dcacf6b7fe151 204 Gene3D G3DSA:3.10.560.10 105 201 1.9E-20 T 29-03-2018 THSYN_RS21370 ee8ac99ab635af81f68dcacf6b7fe151 204 TIGRFAM TIGR03027 pepcterm_export: putative polysaccharide export protein, PEP-CTERM sytem-associated 40 204 4.8E-66 T 29-03-2018 IPR017477 PEP-CTERM, putative polysaccharide export protein THSYN_RS21370 ee8ac99ab635af81f68dcacf6b7fe151 204 Pfam PF02563 Polysaccharide biosynthesis/export protein 36 109 2.6E-21 T 29-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 THSYN_RS27395 d4e3e00581d7ac4c882b766967c70857 133 Gene3D G3DSA:3.40.50.1010 1 128 2.3E-19 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS27395 d4e3e00581d7ac4c882b766967c70857 133 SUPERFAMILY SSF88723 3 128 7.01E-22 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS27395 d4e3e00581d7ac4c882b766967c70857 133 Pfam PF01850 PIN domain 3 119 1.1E-12 T 29-03-2018 IPR002716 PIN domain THSYN_RS18450 8b4efc8364c43443ee7951030254f15e 89 Pfam PF10049 Protein of unknown function (DUF2283) 17 55 2.0E-5 T 29-03-2018 IPR019270 Protein of unknown function DUF2283 THSYN_RS13060 1b8fe63c1b1ce6670f4e585930a4d271 301 Gene3D G3DSA:3.20.20.140 4 255 4.9E-39 T 29-03-2018 THSYN_RS13060 1b8fe63c1b1ce6670f4e585930a4d271 301 SUPERFAMILY SSF89550 165 281 5.3E-48 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 THSYN_RS13060 1b8fe63c1b1ce6670f4e585930a4d271 301 SUPERFAMILY SSF89550 4 83 5.3E-48 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 THSYN_RS13060 1b8fe63c1b1ce6670f4e585930a4d271 301 SMART SM00481 5 70 1.8E-17 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal THSYN_RS13060 1b8fe63c1b1ce6670f4e585930a4d271 301 Pfam PF02811 PHP domain 6 122 1.1E-7 T 29-03-2018 IPR004013 PHP domain GO:0003824 THSYN_RS31660 889ab549379f7e2701a5a1f22cf4dfd8 204 Pfam PF03703 Bacterial PH domain 95 184 1.5E-14 T 29-03-2018 IPR005182 Domain of unknown function DUF304 THSYN_RS14580 ed11dd8d59ae1e7a0321c1a2e8f59d7e 245 SMART SM00382 26 213 3.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS14580 ed11dd8d59ae1e7a0321c1a2e8f59d7e 245 Gene3D G3DSA:3.40.50.300 1 236 3.1E-62 T 29-03-2018 THSYN_RS14580 ed11dd8d59ae1e7a0321c1a2e8f59d7e 245 SUPERFAMILY SSF52540 1 222 5.94E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS14580 ed11dd8d59ae1e7a0321c1a2e8f59d7e 245 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THSYN_RS14580 ed11dd8d59ae1e7a0321c1a2e8f59d7e 245 Pfam PF00005 ABC transporter 18 163 1.0E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS01125 d79a8ae3df9315104fa82b1468700e92 96 TIGRFAM TIGR04535 ferrit_encaps: ferritin-like protein 6 94 9.4E-43 T 29-03-2018 IPR030907 Ferritin-like protein THSYN_RS01125 d79a8ae3df9315104fa82b1468700e92 96 SUPERFAMILY SSF47240 5 93 4.82E-26 T 29-03-2018 IPR009078 Ferritin-like superfamily THSYN_RS01125 d79a8ae3df9315104fa82b1468700e92 96 Gene3D G3DSA:1.20.1260.10 1 84 5.3E-10 T 29-03-2018 IPR012347 Ferritin-related THSYN_RS24420 520ed6dc2ef2438f9930c72e26437952 528 Pfam PF13148 Protein of unknown function (DUF3987) 75 447 4.3E-81 T 29-03-2018 IPR025048 Protein of unknown function DUF3987) THSYN_RS14965 1dd61f93498e496d52646ac5909e247d 180 Gene3D G3DSA:2.60.40.10 74 161 1.2E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS21785 b36228454fa936d064c0b6c2a8bc12b0 244 Gene3D G3DSA:3.90.640.20 152 243 1.7E-10 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 THSYN_RS21785 b36228454fa936d064c0b6c2a8bc12b0 244 Pfam PF11738 Protein of unknown function (DUF3298) 153 229 1.9E-7 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 THSYN_RS21785 b36228454fa936d064c0b6c2a8bc12b0 244 Gene3D G3DSA:3.30.565.40 36 148 1.9E-10 T 29-03-2018 THSYN_RS30345 6094113ba96662baa4b1b5585179f764 108 Gene3D G3DSA:3.30.70.120 9 108 1.4E-4 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THSYN_RS30345 6094113ba96662baa4b1b5585179f764 108 SUPERFAMILY SSF54913 14 89 4.77E-5 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THSYN_RS30345 6094113ba96662baa4b1b5585179f764 108 Pfam PF11582 Protein of unknown function (DUF3240) 12 107 8.7E-18 T 29-03-2018 IPR021634 Protein of unknown function DUF3240 THSYN_RS12260 0ccefaac3a7b685765194480d3b90bd1 195 Pfam PF04754 Putative transposase, YhgA-like 1 88 2.6E-12 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS13905 645485cc1cd4a63c4c7979ac0c80d8b5 76 SUPERFAMILY SSF47598 24 67 1.58E-6 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS13905 645485cc1cd4a63c4c7979ac0c80d8b5 76 Pfam PF08681 Protein of unknown function (DUF1778) 25 69 6.7E-9 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 THSYN_RS13905 645485cc1cd4a63c4c7979ac0c80d8b5 76 Gene3D G3DSA:1.20.5.780 23 69 1.8E-9 T 29-03-2018 THSYN_RS07000 397039827ca79af62727693c4237af90 118 Gene3D G3DSA:3.40.1260.10 1 118 4.5E-27 T 29-03-2018 THSYN_RS07000 397039827ca79af62727693c4237af90 118 Pfam PF02635 DsrE/DsrF-like family 1 118 1.6E-18 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein THSYN_RS07000 397039827ca79af62727693c4237af90 118 SUPERFAMILY SSF75169 1 118 1.34E-24 T 29-03-2018 IPR027396 DsrEFH-like THSYN_RS17760 0be49b9e9d753340d9a3c9d01c015956 265 Pfam PF09335 SNARE associated Golgi protein 94 213 3.7E-19 T 29-03-2018 IPR032816 SNARE associated Golgi protein THSYN_RS10395 4aba60dcb449b9e40f7783309a40ef7f 207 Pfam PF07603 Protein of unknown function (DUF1566) 19 167 2.4E-13 T 29-03-2018 IPR011460 Protein of unknown function DUF1566 THSYN_RS31100 c8ae0d48a9b3f8a65d3e06e80a87e68b 202 Gene3D G3DSA:1.10.3290.10 17 180 3.1E-9 T 29-03-2018 IPR003812 Fido domain THSYN_RS31100 c8ae0d48a9b3f8a65d3e06e80a87e68b 202 SUPERFAMILY SSF140931 89 167 1.96E-6 T 29-03-2018 IPR003812 Fido domain THSYN_RS09630 9d4c9584dd85949459da456ca3816240 88 ProSitePatterns PS00018 EF-hand calcium-binding domain. 28 40 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS09630 9d4c9584dd85949459da456ca3816240 88 Gene3D G3DSA:1.10.1330.10 11 70 0.0012 T 29-03-2018 THSYN_RS14785 2baa46d464f8ffd5b926cd4037f6d4bf 207 Pfam PF07603 Protein of unknown function (DUF1566) 31 177 3.5E-13 T 29-03-2018 IPR011460 Protein of unknown function DUF1566 THSYN_RS14785 2baa46d464f8ffd5b926cd4037f6d4bf 207 Pfam PF07589 PEP-CTERM motif 181 200 2.2E-4 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS23340 f021db8ee00aa095fbbf886f331add1e 142 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 138 12.271 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS23340 f021db8ee00aa095fbbf886f331add1e 142 Pfam PF01850 PIN domain 5 126 8.1E-15 T 29-03-2018 IPR002716 PIN domain THSYN_RS23340 f021db8ee00aa095fbbf886f331add1e 142 SUPERFAMILY SSF88723 4 139 1.15E-30 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS23340 f021db8ee00aa095fbbf886f331add1e 142 Gene3D G3DSA:3.40.50.1010 4 141 3.6E-24 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS31220 8dd0de242de7b90fb47c4108469e5015 945 Gene3D G3DSA:3.10.350.10 50 135 2.0E-12 T 29-03-2018 THSYN_RS31220 8dd0de242de7b90fb47c4108469e5015 945 SUPERFAMILY SSF54106 56 98 4.97E-8 T 29-03-2018 IPR018392 LysM domain THSYN_RS31220 8dd0de242de7b90fb47c4108469e5015 945 Pfam PF01476 LysM domain 57 98 3.2E-10 T 29-03-2018 IPR018392 LysM domain THSYN_RS31220 8dd0de242de7b90fb47c4108469e5015 945 SMART SM00257 56 99 1.1E-10 T 29-03-2018 IPR018392 LysM domain THSYN_RS02635 3480034cb96025dbfd946df9f5d6950e 75 Pfam PF10276 Zinc-finger domain 35 71 1.6E-7 T 29-03-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS02635 3480034cb96025dbfd946df9f5d6950e 75 Gene3D G3DSA:2.60.260.40 19 73 5.0E-15 T 29-03-2018 THSYN_RS10575 0c69175f4cb872bdf6cbd193fb9ca141 287 SUPERFAMILY SSF52980 7 167 2.84E-29 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS10575 0c69175f4cb872bdf6cbd193fb9ca141 287 Pfam PF05685 Putative restriction endonuclease 45 158 4.3E-19 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS10575 0c69175f4cb872bdf6cbd193fb9ca141 287 Gene3D G3DSA:3.90.1570.10 21 159 3.8E-22 T 29-03-2018 THSYN_RS26215 ebe8521d0a9fb52a39dfbdb398c9f3d1 143 Pfam PF10116 Protein required for attachment to host cells 4 138 2.4E-39 T 29-03-2018 IPR019291 Host attachment protein THSYN_RS26215 ebe8521d0a9fb52a39dfbdb398c9f3d1 143 Gene3D G3DSA:3.30.420.60 2 139 1.6E-13 T 29-03-2018 THSYN_RS26320 02a518ca5af2264c8f139ce29fe4b88b 85 Pfam PF03683 Uncharacterised protein family (UPF0175) 13 81 9.4E-22 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS03840 0d29ec752b5694679e78fa83db431c06 200 Pfam PF11845 Protein of unknown function (DUF3365) 33 198 1.6E-26 T 29-03-2018 IPR021796 Protein of unknown function DUF3365 THSYN_RS13065 855fd9eaa7e830917b70ada8ebdd1616 209 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 201 4.0E-63 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 THSYN_RS13065 855fd9eaa7e830917b70ada8ebdd1616 209 Gene3D G3DSA:3.90.870.10 1 206 2.3E-58 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain THSYN_RS13065 855fd9eaa7e830917b70ada8ebdd1616 209 Pfam PF01300 Telomere recombination 22 198 4.3E-45 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 THSYN_RS13065 855fd9eaa7e830917b70ada8ebdd1616 209 SUPERFAMILY SSF55821 1 203 3.36E-63 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain THSYN_RS23200 67fa81fae10d585be5535f229d816b57 131 Pfam PF03330 Lytic transglycolase 31 119 1.2E-25 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain THSYN_RS23200 67fa81fae10d585be5535f229d816b57 131 SUPERFAMILY SSF50685 21 119 6.63E-14 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain THSYN_RS23200 67fa81fae10d585be5535f229d816b57 131 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 7 123 22.515 T 29-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 THSYN_RS23200 67fa81fae10d585be5535f229d816b57 131 Gene3D G3DSA:2.40.40.10 17 123 2.1E-20 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain THSYN_RS23200 67fa81fae10d585be5535f229d816b57 131 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 33 129 8.9E-43 T 29-03-2018 IPR012997 Rare lipoprotein A THSYN_RS20730 c5d3a87e4a56c11ca1bacb7e3e418143 150 Pfam PF14467 Domain of unknown function (DUF4426) 28 148 2.4E-29 T 29-03-2018 IPR025218 Domain of unknown function DUF4426 THSYN_RS30725 997c67d35244c3be62fe10211c5504b0 278 Pfam PF04434 SWIM zinc finger 130 151 7.8E-6 T 29-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 THSYN_RS18075 30e65b391cf5357214feadc8b8e36df8 660 SUPERFAMILY SSF53335 325 353 8.23E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS18075 30e65b391cf5357214feadc8b8e36df8 660 SUPERFAMILY SSF53335 551 659 8.23E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS18075 30e65b391cf5357214feadc8b8e36df8 660 SUPERFAMILY SSF53335 382 439 8.23E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS18075 30e65b391cf5357214feadc8b8e36df8 660 SUPERFAMILY SSF53335 94 263 8.23E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS18075 30e65b391cf5357214feadc8b8e36df8 660 Gene3D G3DSA:3.40.50.150 243 660 3.2E-25 T 29-03-2018 THSYN_RS01885 c7fc56b68098990c42d46ca22ddeeb32 106 Gene3D G3DSA:3.30.70.790 1 70 9.2E-15 T 29-03-2018 THSYN_RS01885 c7fc56b68098990c42d46ca22ddeeb32 106 Pfam PF09413 Putative prokaryotic signal transducing protein 1 67 6.0E-11 T 29-03-2018 IPR018551 Domain of unknown function DUF2007 THSYN_RS15550 7c3d973114270406167413f5970d90c3 162 Gene3D G3DSA:1.10.1660.10 1 47 1.0E-5 T 29-03-2018 THSYN_RS15550 7c3d973114270406167413f5970d90c3 162 Pfam PF12728 Helix-turn-helix domain 3 44 9.2E-10 T 29-03-2018 THSYN_RS15550 7c3d973114270406167413f5970d90c3 162 SUPERFAMILY SSF46955 1 43 6.04E-6 T 29-03-2018 IPR009061 Putative DNA-binding domain THSYN_RS15550 7c3d973114270406167413f5970d90c3 162 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 3 43 6.8E-9 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 THSYN_RS08635 e9fcf798582e41adbdc381085baba129 99 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 14 92 3.5E-20 T 29-03-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THSYN_RS17000 6dbad2b9bc83d430d6442891631b3588 241 Gene3D G3DSA:3.40.50.300 15 238 2.0E-19 T 29-03-2018 THSYN_RS17000 6dbad2b9bc83d430d6442891631b3588 241 SUPERFAMILY SSF52540 29 211 5.91E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS26480 da4690f6ba8d3aef21fa5e8384ae846b 324 Gene3D G3DSA:3.30.450.40 5 169 5.1E-18 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS26480 da4690f6ba8d3aef21fa5e8384ae846b 324 SMART SM00065 29 177 7.6E-4 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS26480 da4690f6ba8d3aef21fa5e8384ae846b 324 Pfam PF13185 GAF domain 34 166 4.2E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 THSYN_RS26480 da4690f6ba8d3aef21fa5e8384ae846b 324 SUPERFAMILY SSF55781 17 166 1.07E-16 T 29-03-2018 IPR029016 GAF domain-like THSYN_RS31390 75b0a85a376e3c30c93124482f61dbe8 385 Gene3D G3DSA:1.10.468.10 172 327 6.2E-32 T 29-03-2018 THSYN_RS31390 75b0a85a376e3c30c93124482f61dbe8 385 Gene3D G3DSA:1.10.468.10 26 170 4.1E-30 T 29-03-2018 THSYN_RS31390 75b0a85a376e3c30c93124482f61dbe8 385 SUPERFAMILY SSF48695 26 343 5.28E-96 T 29-03-2018 IPR011031 Multihaem cytochrome THSYN_RS31390 75b0a85a376e3c30c93124482f61dbe8 385 Pfam PF02276 Photosynthetic reaction centre cytochrome C subunit 28 342 7.1E-118 T 29-03-2018 IPR003158 Photosynthetic reaction centre, cytochrome c subunit GO:0005506|GO:0009055|GO:0019684|GO:0020037|GO:0030077 THSYN_RS31390 75b0a85a376e3c30c93124482f61dbe8 385 PIRSF PIRSF000017 5 371 5.3E-122 T 29-03-2018 IPR003158 Photosynthetic reaction centre, cytochrome c subunit GO:0005506|GO:0009055|GO:0019684|GO:0020037|GO:0030077 THSYN_RS11525 bf433410ad9a5d05ca9bbbce02e76742 281 SMART SM00090 5 234 8.1E-23 T 29-03-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|Reactome: R-HSA-6791226 THSYN_RS11525 bf433410ad9a5d05ca9bbbce02e76742 281 Pfam PF01163 RIO1 family 55 219 4.6E-42 T 29-03-2018 THSYN_RS11525 bf433410ad9a5d05ca9bbbce02e76742 281 SUPERFAMILY SSF56112 18 223 4.5E-20 T 29-03-2018 IPR011009 Protein kinase-like domain THSYN_RS11525 bf433410ad9a5d05ca9bbbce02e76742 281 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 164 175 - T 29-03-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|Reactome: R-HSA-6791226 THSYN_RS11525 bf433410ad9a5d05ca9bbbce02e76742 281 Gene3D G3DSA:1.10.510.10 126 235 5.0E-6 T 29-03-2018 THSYN_RS11525 bf433410ad9a5d05ca9bbbce02e76742 281 Gene3D G3DSA:3.30.200.20 16 125 2.1E-21 T 29-03-2018 THSYN_RS25180 f1f7fe00cd9c09ef1dbe51e700f7cce7 107 SUPERFAMILY SSF51182 22 95 6.88E-8 T 29-03-2018 IPR011051 RmlC-like cupin domain THSYN_RS25180 f1f7fe00cd9c09ef1dbe51e700f7cce7 107 Gene3D G3DSA:2.60.120.10 1 96 3.2E-8 T 29-03-2018 IPR014710 RmlC-like jelly roll fold THSYN_RS05125 9ffe6d51f6262550e13ed14555065c88 586 Gene3D G3DSA:3.90.1580.10 331 586 1.1E-55 T 29-03-2018 THSYN_RS05125 9ffe6d51f6262550e13ed14555065c88 586 Pfam PF03781 Sulfatase-modifying factor enzyme 1 378 579 2.4E-44 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS05125 9ffe6d51f6262550e13ed14555065c88 586 SUPERFAMILY SSF56436 363 579 3.58E-58 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS22385 b4b1be8c9838a76b86af15f99391b5d4 395 Gene3D G3DSA:1.20.1170.10 17 379 1.9E-4 T 29-03-2018 THSYN_RS22385 b4b1be8c9838a76b86af15f99391b5d4 395 PIRSF PIRSF026508 16 379 2.4E-101 T 29-03-2018 IPR008863 Toxic anion resistance THSYN_RS22385 b4b1be8c9838a76b86af15f99391b5d4 395 Pfam PF05816 Toxic anion resistance protein (TelA) 43 371 4.3E-111 T 29-03-2018 IPR008863 Toxic anion resistance THSYN_RS13860 43c4eaeb0ff5bf30f7610edd185b9401 186 Pfam PF04012 PspA/IM30 family 4 149 1.8E-11 T 29-03-2018 IPR007157 PspA/IM30 THSYN_RS30895 cd9bbc7872824a70f07f7fb6a3432a7f 122 Pfam PF08281 Sigma-70, region 4 63 108 7.1E-8 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS30895 cd9bbc7872824a70f07f7fb6a3432a7f 122 Gene3D G3DSA:1.10.10.10 25 118 3.0E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS30895 cd9bbc7872824a70f07f7fb6a3432a7f 122 SUPERFAMILY SSF88659 62 116 2.06E-9 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THSYN_RS23970 483f0d731727b04def98c221d8826771 460 SUPERFAMILY SSF53098 119 371 3.87E-21 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS23970 483f0d731727b04def98c221d8826771 460 Gene3D G3DSA:3.90.350.10 120 344 1.1E-7 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS23970 483f0d731727b04def98c221d8826771 460 Pfam PF01609 Transposase DDE domain 131 361 6.5E-16 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THSYN_RS03045 de4dc03fa678ef4d708406ecc51a5e34 239 SUPERFAMILY SSF52540 3 89 8.62E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS03045 de4dc03fa678ef4d708406ecc51a5e34 239 Gene3D G3DSA:3.40.50.300 2 225 1.2E-6 T 29-03-2018 THSYN_RS33200 1c14fb85a0c71baeb853085c7c4c0a2f 177 Pfam PF02441 Flavoprotein 8 154 9.6E-14 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 THSYN_RS33200 1c14fb85a0c71baeb853085c7c4c0a2f 177 Gene3D G3DSA:3.40.50.1950 3 174 3.3E-22 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 THSYN_RS33200 1c14fb85a0c71baeb853085c7c4c0a2f 177 SUPERFAMILY SSF52507 7 166 2.22E-20 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 THSYN_RS32815 6e9f671db39ec3f12e0cc779ef710855 348 TIGRFAM TIGR03363 VI_chp_8: type VI secretion-associated protein, ImpA family 7 343 3.0E-76 T 29-03-2018 IPR017740 Type VI secretion system-associated, ImpA THSYN_RS32815 6e9f671db39ec3f12e0cc779ef710855 348 Pfam PF06812 ImpA, N-terminal, type VI secretion system 10 133 3.7E-32 T 29-03-2018 IPR010657 ImpA, N-terminal THSYN_RS00515 5c6a420c2dd53193f1592580136bf73e 484 PIRSF PIRSF006247 1 484 1.0E-163 T 29-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 THSYN_RS00515 5c6a420c2dd53193f1592580136bf73e 484 Pfam PF02386 Cation transport protein 44 478 1.5E-61 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 THSYN_RS08150 c23b9963338fb0ed32737121fabf35c8 138 Gene3D G3DSA:3.40.50.1010 1 137 1.4E-13 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS08150 c23b9963338fb0ed32737121fabf35c8 138 SUPERFAMILY SSF88723 1 130 7.85E-13 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS08150 c23b9963338fb0ed32737121fabf35c8 138 Pfam PF13470 PIN domain 2 114 2.1E-8 T 29-03-2018 IPR002716 PIN domain THSYN_RS20425 43121ea5d52c7cb78ef640907e2bc8d6 170 Pfam PF11848 Domain of unknown function (DUF3368) 113 157 6.7E-8 T 29-03-2018 IPR021799 Protein of unknown function DUF3368 THSYN_RS24030 0d2aac9fd16baa58d8181cd6d034060e 114 Gene3D G3DSA:1.20.120.450 53 102 0.016 T 29-03-2018 THSYN_RS06810 b31631e1a768b95cc24d3bca6473333a 646 SUPERFAMILY SSF53795 209 255 1.01E-6 T 29-03-2018 THSYN_RS06810 b31631e1a768b95cc24d3bca6473333a 646 Pfam PF00535 Glycosyl transferase family 2 419 510 2.5E-25 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THSYN_RS06810 b31631e1a768b95cc24d3bca6473333a 646 Gene3D G3DSA:3.90.550.10 405 636 1.6E-45 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS06810 b31631e1a768b95cc24d3bca6473333a 646 SUPERFAMILY SSF53448 416 622 2.72E-48 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS01620 0eb0cb7518a4eeb692d869808adac039 461 SUPERFAMILY SSF48371 409 447 6.58E-11 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS01620 0eb0cb7518a4eeb692d869808adac039 461 SUPERFAMILY SSF48371 156 348 6.58E-11 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS01620 0eb0cb7518a4eeb692d869808adac039 461 Gene3D G3DSA:1.25.10.10 48 458 5.4E-14 T 29-03-2018 IPR011989 Armadillo-like helical THSYN_RS06430 8e012b3a2dde9669076e3dffbcbdf740 698 Gene3D G3DSA:3.40.50.410 226 481 1.6E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS06430 8e012b3a2dde9669076e3dffbcbdf740 698 SUPERFAMILY SSF53300 231 364 1.88E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS06430 8e012b3a2dde9669076e3dffbcbdf740 698 SUPERFAMILY SSF53300 392 414 1.88E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 Gene3D G3DSA:2.60.40.1180 13 92 4.0E-27 T 29-03-2018 THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 Gene3D G3DSA:2.60.40.1180 93 123 1.3E-21 T 29-03-2018 THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 Gene3D G3DSA:2.60.40.1180 204 228 3.5E-18 T 29-03-2018 THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 Gene3D G3DSA:2.60.40.1180 157 203 1.1E-24 T 29-03-2018 THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 Gene3D G3DSA:2.60.40.1180 229 267 3.0E-15 T 29-03-2018 THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 Gene3D G3DSA:2.60.40.1180 124 156 1.5E-20 T 29-03-2018 THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 SUPERFAMILY SSF81901 11 160 1.83E-47 T 29-03-2018 THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 SUPERFAMILY SSF81901 144 262 5.89E-38 T 29-03-2018 THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 Pfam PF08238 Sel1 repeat 149 182 8.4E-8 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 Pfam PF08238 Sel1 repeat 77 110 5.5E-11 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 Pfam PF08238 Sel1 repeat 112 146 1.3E-8 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 Pfam PF08238 Sel1 repeat 219 254 4.7E-10 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 Pfam PF08238 Sel1 repeat 184 217 1.0E-10 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 Pfam PF08238 Sel1 repeat 41 74 5.5E-11 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 SMART SM00671 111 146 3.2E-11 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 SMART SM00671 75 110 3.2E-13 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 SMART SM00671 219 254 8.8E-14 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 SMART SM00671 39 74 3.2E-13 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 SMART SM00671 147 182 9.6E-11 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS27445 b1e480a98e70ad70530a4614ac735471 267 SMART SM00671 183 218 6.8E-13 T 29-03-2018 IPR006597 Sel1-like repeat THSYN_RS24240 477e73aa5de0fc201b4c1f14499d5b74 297 SUPERFAMILY SSF52540 4 228 5.56E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS24240 477e73aa5de0fc201b4c1f14499d5b74 297 Pfam PF13469 Sulfotransferase family 11 212 2.1E-13 T 29-03-2018 THSYN_RS24240 477e73aa5de0fc201b4c1f14499d5b74 297 Gene3D G3DSA:3.40.50.300 1 294 3.4E-21 T 29-03-2018 THSYN_RS31755 7623f3b36f2b46362a80d2c91d7448e7 308 SUPERFAMILY SSF51126 31 273 5.37E-26 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor THSYN_RS31755 7623f3b36f2b46362a80d2c91d7448e7 308 SMART SM00710 122 143 2.5 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS31755 7623f3b36f2b46362a80d2c91d7448e7 308 SMART SM00710 224 251 4700.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS31755 7623f3b36f2b46362a80d2c91d7448e7 308 SMART SM00710 258 281 4900.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS31755 7623f3b36f2b46362a80d2c91d7448e7 308 SMART SM00710 95 121 920.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat THSYN_RS31755 7623f3b36f2b46362a80d2c91d7448e7 308 Gene3D G3DSA:2.160.20.10 28 307 2.5E-26 T 29-03-2018 IPR012334 Pectin lyase fold THSYN_RS11810 1364ee01c296c967d33e147e7d68098c 264 SUPERFAMILY SSF54427 150 258 1.37E-7 T 29-03-2018 IPR032710 NTF2-like domain THSYN_RS11810 1364ee01c296c967d33e147e7d68098c 264 Gene3D G3DSA:3.10.450.50 139 257 3.2E-7 T 29-03-2018 THSYN_RS13190 f686db81b3bc61efd0cc95b2beed4cfb 164 Pfam PF11848 Domain of unknown function (DUF3368) 114 160 2.6E-16 T 29-03-2018 IPR021799 Protein of unknown function DUF3368 THSYN_RS28950 9c713f34f9c53a1973405e38e261fafd 902 SUPERFAMILY SSF110296 652 896 1.62E-20 T 29-03-2018 THSYN_RS28950 9c713f34f9c53a1973405e38e261fafd 902 Gene3D G3DSA:2.130.10.10 334 593 3.0E-16 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS28950 9c713f34f9c53a1973405e38e261fafd 902 Gene3D G3DSA:2.130.10.10 605 715 1.8E-8 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS28950 9c713f34f9c53a1973405e38e261fafd 902 SUPERFAMILY SSF110296 566 675 4.45E-13 T 29-03-2018 THSYN_RS28950 9c713f34f9c53a1973405e38e261fafd 902 SUPERFAMILY SSF110296 337 529 4.45E-13 T 29-03-2018 THSYN_RS28950 9c713f34f9c53a1973405e38e261fafd 902 SUPERFAMILY SSF110296 132 398 1.54E-34 T 29-03-2018 THSYN_RS28950 9c713f34f9c53a1973405e38e261fafd 902 Gene3D G3DSA:2.130.10.10 718 900 5.6E-23 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS28950 9c713f34f9c53a1973405e38e261fafd 902 Gene3D G3DSA:2.130.10.10 142 333 7.2E-32 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS26210 1a598784fbf06f29686161bc9fbc5421 163 Pfam PF01864 CDP-archaeol synthase 79 145 1.9E-7 T 29-03-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 THSYN_RS02965 518caa8e93670806d53a695f9d92b478 199 Gene3D G3DSA:2.50.20.10 29 195 3.0E-17 T 29-03-2018 THSYN_RS02965 518caa8e93670806d53a695f9d92b478 199 SUPERFAMILY SSF89392 34 193 4.71E-14 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX THSYN_RS18490 23e16919d0e57c58f1627b262af48b64 488 Pfam PF02447 GntP family permease 3 162 3.3E-10 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 THSYN_RS12770 b276ce4709e2e191643f4b69aad65689 179 Gene3D G3DSA:3.40.50.700 56 178 7.5E-30 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS12770 b276ce4709e2e191643f4b69aad65689 179 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 55 165 8.3E-27 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS12770 b276ce4709e2e191643f4b69aad65689 179 SUPERFAMILY SSF56770 41 167 3.27E-49 T 29-03-2018 THSYN_RS31925 713a301fdb50b3c8fe7f0da78e3349ff 81 Pfam PF03683 Uncharacterised protein family (UPF0175) 8 75 3.3E-19 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS06025 6a089ea4a8305a3a357f360a52259652 901 Gene3D G3DSA:3.40.50.300 1 258 7.0E-12 T 29-03-2018 THSYN_RS06025 6a089ea4a8305a3a357f360a52259652 901 SUPERFAMILY SSF52540 63 116 4.5E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06025 6a089ea4a8305a3a357f360a52259652 901 SUPERFAMILY SSF52540 333 424 4.5E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06025 6a089ea4a8305a3a357f360a52259652 901 Pfam PF04851 Type III restriction enzyme, res subunit 5 249 6.8E-15 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THSYN_RS06025 6a089ea4a8305a3a357f360a52259652 901 SUPERFAMILY SSF52540 61 161 8.05E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS06025 6a089ea4a8305a3a357f360a52259652 901 SUPERFAMILY SSF52540 206 250 8.05E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS33085 71337913449f79dd8ee9ae10ca81ba1c 318 Pfam PF00589 Phage integrase family 112 291 8.5E-17 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS33085 71337913449f79dd8ee9ae10ca81ba1c 318 Gene3D G3DSA:1.10.443.10 106 296 2.2E-29 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THSYN_RS33085 71337913449f79dd8ee9ae10ca81ba1c 318 SUPERFAMILY SSF56349 70 293 3.53E-30 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS19190 58ad71e984335c579c62e5d1b871a59f 539 Gene3D G3DSA:2.40.160.10 101 530 7.5E-39 T 29-03-2018 THSYN_RS19190 58ad71e984335c579c62e5d1b871a59f 539 Pfam PF00593 TonB dependent receptor 337 507 1.0E-5 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THSYN_RS19190 58ad71e984335c579c62e5d1b871a59f 539 SUPERFAMILY SSF56935 169 508 4.66E-12 T 29-03-2018 THSYN_RS22580 9110fcf4b85dc1621401df7528dd19e2 442 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 4 126 1.4E-25 T 29-03-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI THSYN_RS22580 9110fcf4b85dc1621401df7528dd19e2 442 Gene3D G3DSA:1.25.40.10 217 292 2.5E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22580 9110fcf4b85dc1621401df7528dd19e2 442 Pfam PF13428 Tetratricopeptide repeat 173 213 1.1E-5 T 29-03-2018 THSYN_RS22580 9110fcf4b85dc1621401df7528dd19e2 442 SUPERFAMILY SSF48452 163 267 1.34E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS22580 9110fcf4b85dc1621401df7528dd19e2 442 Gene3D G3DSA:1.25.40.10 52 216 1.9E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS02510 eb8032c35f5a7c954046a54784d4dcc6 337 SUPERFAMILY SSF158544 137 230 2.04E-24 T 29-03-2018 THSYN_RS02510 eb8032c35f5a7c954046a54784d4dcc6 337 Gene3D G3DSA:1.10.40.60 123 233 1.1E-23 T 29-03-2018 THSYN_RS02510 eb8032c35f5a7c954046a54784d4dcc6 337 Pfam PF03934 Type II secretion system (T2SS), protein K 118 267 1.7E-31 T 29-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 THSYN_RS02510 eb8032c35f5a7c954046a54784d4dcc6 337 PIRSF PIRSF002786 17 303 1.2E-29 T 29-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 THSYN_RS25415 1c8a228da02d63ffb619b4cc08e329c1 162 Pfam PF01724 Domain of unknown function DUF29 7 152 1.4E-47 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS24245 312aa5bd71da0192ba68e49c6c399bcc 213 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 176 198 1.5E-6 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS24245 312aa5bd71da0192ba68e49c6c399bcc 213 Pfam PF07589 PEP-CTERM motif 175 197 1.4E-7 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS09410 c58e2cc9e514b50d569406603cfcaf19 80 Pfam PF07704 Rv0623-like transcription factor 15 60 2.7E-9 T 29-03-2018 IPR011660 Antitoxin VapB-like THSYN_RS17290 95001dda8a2531f049d4a02a82ab6793 765 Gene3D G3DSA:1.20.120.330 26 447 0.053 T 29-03-2018 THSYN_RS17290 95001dda8a2531f049d4a02a82ab6793 765 Gene3D G3DSA:1.20.120.330 462 654 0.023 T 29-03-2018 THSYN_RS01215 9d0498bedfdbf80a4f23d27ab42b0c34 171 Pfam PF04191 Phospholipid methyltransferase 89 150 1.9E-6 T 29-03-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 THSYN_RS32610 ef252619443b4def9aee261ae6e12241 145 SUPERFAMILY SSF53850 34 132 8.8E-9 T 29-03-2018 THSYN_RS32610 ef252619443b4def9aee261ae6e12241 145 Gene3D G3DSA:3.40.190.10 24 136 1.6E-6 T 29-03-2018 THSYN_RS12510 1f3776ae8fafc4cc464e96dcf4ee244c 74 Pfam PF12728 Helix-turn-helix domain 7 56 6.6E-15 T 29-03-2018 THSYN_RS12510 1f3776ae8fafc4cc464e96dcf4ee244c 74 Gene3D G3DSA:1.10.10.10 6 65 9.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS12510 1f3776ae8fafc4cc464e96dcf4ee244c 74 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 53 6.7E-11 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 THSYN_RS12510 1f3776ae8fafc4cc464e96dcf4ee244c 74 SUPERFAMILY SSF46955 6 58 2.01E-8 T 29-03-2018 IPR009061 Putative DNA-binding domain THSYN_RS32085 dff1fdd57a3ee2ed2dbd9ab93982684c 51 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 6 50 1.3E-7 T 29-03-2018 IPR022453 Zinc finger, MqsA-type THSYN_RS11710 313d0e71947e402a57646d4d66e0d2cf 432 SUPERFAMILY SSF51445 3 335 2.22E-57 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily THSYN_RS11710 313d0e71947e402a57646d4d66e0d2cf 432 SMART SM00642 7 329 4.2E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THSYN_RS11710 313d0e71947e402a57646d4d66e0d2cf 432 Pfam PF14701 Glycogen debranching enzyme, glucanotransferase domain 10 107 5.2E-17 T 29-03-2018 IPR032792 Glycogen debranching enzyme, glucanotransferase domain KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 THSYN_RS11710 313d0e71947e402a57646d4d66e0d2cf 432 Gene3D G3DSA:3.20.20.80 3 335 5.0E-51 T 29-03-2018 THSYN_RS03675 c7fbd6d1cedb9c889947141cd2be88e5 313 Gene3D G3DSA:3.40.50.10330 8 158 9.3E-13 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 THSYN_RS03675 c7fbd6d1cedb9c889947141cd2be88e5 313 Gene3D G3DSA:2.60.200.30 159 306 1.1E-23 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 THSYN_RS03675 c7fbd6d1cedb9c889947141cd2be88e5 313 SUPERFAMILY SSF111331 77 210 1.6E-12 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain THSYN_RS31890 ecd42bb0cc191bd5ff432cbb7a5e9fd6 81 Gene3D G3DSA:1.10.1220.10 4 44 3.3E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS31890 ecd42bb0cc191bd5ff432cbb7a5e9fd6 81 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 3 66 5.0E-13 T 29-03-2018 IPR022789 Antitoxin ParD THSYN_RS31890 ecd42bb0cc191bd5ff432cbb7a5e9fd6 81 SUPERFAMILY SSF47598 1 44 7.34E-7 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS18875 3e4616fb6bf270e287d18173e6d8f387 187 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS18875 3e4616fb6bf270e287d18173e6d8f387 187 Gene3D G3DSA:3.30.700.10 11 176 2.8E-14 T 29-03-2018 THSYN_RS18875 3e4616fb6bf270e287d18173e6d8f387 187 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 2.3E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS18875 3e4616fb6bf270e287d18173e6d8f387 187 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 29 1.1E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site THSYN_RS18875 3e4616fb6bf270e287d18173e6d8f387 187 SUPERFAMILY SSF54523 11 105 3.53E-14 T 29-03-2018 THSYN_RS18875 3e4616fb6bf270e287d18173e6d8f387 187 Pfam PF12019 Type II transport protein GspH 46 169 2.4E-14 T 29-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THSYN_RS15050 4f199df014ccb454e8017c7206b64e81 330 SUPERFAMILY SSF53300 103 179 6.67E-6 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS15050 4f199df014ccb454e8017c7206b64e81 330 Gene3D G3DSA:3.40.50.410 78 228 2.6E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS15050 4f199df014ccb454e8017c7206b64e81 330 Pfam PF01882 Protein of unknown function DUF58 66 148 4.6E-16 T 29-03-2018 IPR002881 Domain of unknown function DUF58 THSYN_RS00220 33975d2c08f4cc6ad219755584f5af11 542 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 68 231 1.7E-16 T 29-03-2018 THSYN_RS01345 1fc0f5c97d3e48997ae051a1d2f0a3d5 140 Gene3D G3DSA:1.20.120.50 1 75 3.1E-4 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 THSYN_RS01135 75d90b23ecf2edc7e63d716e3933edb5 507 Gene3D G3DSA:3.40.50.1820 227 398 1.2E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS01135 75d90b23ecf2edc7e63d716e3933edb5 507 SUPERFAMILY SSF53474 230 400 6.93E-13 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS27805 353f6c7eb0d7ea89f8294ae95a96b426 128 Pfam PF04379 ApaG domain 20 105 2.6E-35 T 29-03-2018 IPR007474 ApaG domain THSYN_RS27805 353f6c7eb0d7ea89f8294ae95a96b426 128 Hamap MF_00791 Protein ApaG [apaG]. 3 128 32.329 T 29-03-2018 IPR023065 Uncharacterised protein family ApaG THSYN_RS27805 353f6c7eb0d7ea89f8294ae95a96b426 128 SUPERFAMILY SSF110069 8 123 2.75E-47 T 29-03-2018 IPR007474 ApaG domain THSYN_RS27805 353f6c7eb0d7ea89f8294ae95a96b426 128 Gene3D G3DSA:2.60.40.1470 3 128 3.5E-43 T 29-03-2018 IPR007474 ApaG domain THSYN_RS11965 81b4ea47f663ade8ff31b3eb3278d645 159 Pfam PF01724 Domain of unknown function DUF29 7 152 1.5E-49 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS04820 7bde2ad198d482c52b16f5d0d60ea24d 122 Pfam PF11191 Protein of unknown function (DUF2782) 42 121 1.8E-26 T 29-03-2018 IPR021357 Protein of unknown function DUF2782 THSYN_RS19065 8d7d81aec35241c06d16b43dbfdcadcd 40 Pfam PF08173 Membrane bound YbgT-like protein 1 26 4.0E-15 T 29-03-2018 IPR012994 Membrane bound YbgT-like THSYN_RS19065 8d7d81aec35241c06d16b43dbfdcadcd 40 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 26 7.0E-16 T 29-03-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 THSYN_RS01475 67b82012c0e7716a528f6acf8ab755af 66 Pfam PF10047 Protein of unknown function (DUF2281) 7 35 5.2E-6 T 29-03-2018 IPR018739 Domain of unknown function DUF2281 THSYN_RS05945 07f934d1f29d0d57872e3d322b6e0656 249 Pfam PF11769 Protein of unknown function (DUF3313) 34 233 1.0E-41 T 29-03-2018 IPR021747 Protein of unknown function DUF3313 THSYN_RS10625 c0169adc8f1f6ef92417c28ba35e7042 463 SUPERFAMILY SSF52540 56 219 1.43E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS10625 c0169adc8f1f6ef92417c28ba35e7042 463 Gene3D G3DSA:3.40.50.300 1 347 6.6E-5 T 29-03-2018 THSYN_RS10615 ac2e2dac45e3a5356bf0b334e3cf0113 245 Pfam PF04172 LrgB-like family 24 237 5.2E-76 T 29-03-2018 IPR007300 CidB/LrgB family THSYN_RS04340 dda55f3563c46d3e559f00c562668f6b 260 Gene3D G3DSA:3.40.50.1220 6 259 6.2E-46 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS04340 dda55f3563c46d3e559f00c562668f6b 260 Pfam PF02146 Sir2 family 28 201 3.2E-36 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 THSYN_RS04340 dda55f3563c46d3e559f00c562668f6b 260 SUPERFAMILY SSF52467 11 254 5.23E-65 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain THSYN_RS13915 39549aaff003a617fea1f1137e4f5016 453 SUPERFAMILY SSF52540 152 279 4.76E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13915 39549aaff003a617fea1f1137e4f5016 453 SUPERFAMILY SSF52540 313 450 4.76E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13915 39549aaff003a617fea1f1137e4f5016 453 SUPERFAMILY SSF52540 10 97 4.76E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS13915 39549aaff003a617fea1f1137e4f5016 453 Gene3D G3DSA:3.40.50.300 6 453 8.7E-24 T 29-03-2018 THSYN_RS13915 39549aaff003a617fea1f1137e4f5016 453 SMART SM00382 30 452 3.2E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS13915 39549aaff003a617fea1f1137e4f5016 453 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 33 438 3.0E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS17615 0ac4fdff07f4de46432922912bedef21 147 Gene3D G3DSA:1.10.287.130 71 134 7.9E-6 T 29-03-2018 THSYN_RS17615 0ac4fdff07f4de46432922912bedef21 147 SUPERFAMILY SSF47384 74 132 5.1E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS17615 0ac4fdff07f4de46432922912bedef21 147 Pfam PF00512 His Kinase A (phospho-acceptor) domain 74 131 5.0E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THSYN_RS10265 38cf1c22ea609b1f8bf6fff0882fe79d 426 Gene3D G3DSA:1.20.1250.20 224 414 1.2E-17 T 29-03-2018 THSYN_RS10265 38cf1c22ea609b1f8bf6fff0882fe79d 426 SUPERFAMILY SSF103473 8 412 2.88E-33 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS10265 38cf1c22ea609b1f8bf6fff0882fe79d 426 Pfam PF11700 Vacuole effluxer Atg22 like 6 133 7.2E-11 T 29-03-2018 IPR024671 Autophagy-related protein 22-like THSYN_RS10265 38cf1c22ea609b1f8bf6fff0882fe79d 426 Pfam PF11700 Vacuole effluxer Atg22 like 143 422 2.8E-48 T 29-03-2018 IPR024671 Autophagy-related protein 22-like THSYN_RS10265 38cf1c22ea609b1f8bf6fff0882fe79d 426 Gene3D G3DSA:1.20.1250.20 8 215 6.3E-15 T 29-03-2018 THSYN_RS12325 d23a576072b80acd8e4cb5dfd208c762 404 Pfam PF07804 HipA-like C-terminal domain 170 376 1.8E-44 T 29-03-2018 IPR012893 HipA-like, C-terminal THSYN_RS12325 d23a576072b80acd8e4cb5dfd208c762 404 Pfam PF13657 HipA N-terminal domain 32 121 5.7E-13 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 THSYN_RS14575 d1fcff181326dbef537fdd4ab45d7462 170 Pfam PF09828 Chromate resistance exported protein 36 160 1.9E-28 T 29-03-2018 IPR018634 Chromate resistance exported protein THSYN_RS28345 04526234fca3e29aec9134ebfd0b39e7 127 Gene3D G3DSA:1.20.58.130 25 105 1.0E-4 T 29-03-2018 THSYN_RS17795 558b3ac73114de83e7cf412e4db5f856 391 Pfam PF00691 OmpA family 216 308 5.1E-12 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS17795 558b3ac73114de83e7cf412e4db5f856 391 SUPERFAMILY SSF103088 206 321 4.58E-21 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS17795 558b3ac73114de83e7cf412e4db5f856 391 Gene3D G3DSA:3.30.1330.60 63 331 4.8E-27 T 29-03-2018 IPR006665 OmpA-like domain THSYN_RS25355 d2b454f9925334791c145b67be7b3008 136 Gene3D G3DSA:1.10.10.10 1 117 5.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25355 d2b454f9925334791c145b67be7b3008 136 SUPERFAMILY SSF46785 5 111 2.07E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS25355 d2b454f9925334791c145b67be7b3008 136 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 55 9.0E-12 T 29-03-2018 THSYN_RS25355 d2b454f9925334791c145b67be7b3008 136 TIGRFAM TIGR04176 MarR_EPS: EPS-associated transcriptional regulator, MarR family 8 110 2.9E-45 T 29-03-2018 IPR026433 EPS-associated transcriptional regulator, MarR family THSYN_RS05605 71dc66a1b8e5028175e1dc8049ba4cbc 167 Pfam PF14280 Domain of unknown function (DUF4365) 14 160 3.6E-24 T 29-03-2018 IPR025375 Domain of unknown function DUF4365 THSYN_RS09015 09bff9c677ec1d7277e966cd2bccaffc 205 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 5 205 5.8E-63 T 29-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 THSYN_RS09015 09bff9c677ec1d7277e966cd2bccaffc 205 Pfam PF03006 Haemolysin-III related 4 198 1.1E-41 T 29-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 THSYN_RS30900 75dfc0c2cd7e8f4ea8e6e44f70c9c1fe 787 Gene3D G3DSA:1.20.950.20 633 787 5.3E-5 T 29-03-2018 THSYN_RS18050 26ec591f4acb1104348fdd8ffcc29da9 192 Pfam PF08747 Domain of unknown function (DUF1788) 67 188 1.5E-17 T 29-03-2018 IPR014858 Protein of unknown function DUF1788 THSYN_RS21210 44326619725a99d78a1a0de00f1b8c82 201 Gene3D G3DSA:3.40.630.30 91 191 0.017 T 29-03-2018 THSYN_RS21425 86c3351c9b4762ed433d3cb6b9dd5e0d 223 Pfam PF07751 Abi-like protein 34 122 2.6E-24 T 29-03-2018 IPR011664 Abortive infection system protein AbiD/AbiF-like THSYN_RS05285 825d05ede86acdc0c2bc5a98c82fbecf 251 PIRSF PIRSF030802 1 250 3.6E-49 T 29-03-2018 IPR024197 Uncharacterised conserved protein UCP030802 THSYN_RS05285 825d05ede86acdc0c2bc5a98c82fbecf 251 Gene3D G3DSA:3.40.50.1000 5 244 1.6E-8 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS05285 825d05ede86acdc0c2bc5a98c82fbecf 251 SUPERFAMILY SSF56784 43 236 3.46E-14 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS05285 825d05ede86acdc0c2bc5a98c82fbecf 251 SUPERFAMILY SSF56784 6 16 3.46E-14 T 29-03-2018 IPR023214 HAD-like domain THSYN_RS16080 c70817cbb58c56848b3ab07ae077cbdf 272 Gene3D G3DSA:2.40.320.10 24 249 2.2E-16 T 29-03-2018 THSYN_RS16080 c70817cbb58c56848b3ab07ae077cbdf 272 SUPERFAMILY SSF55154 25 92 7.85E-5 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 THSYN_RS04150 dd6cfb9eda34cbf9d84a9d6218ce8209 144 Gene3D G3DSA:2.60.40.730 26 136 5.3E-14 T 29-03-2018 THSYN_RS04150 dd6cfb9eda34cbf9d84a9d6218ce8209 144 SUPERFAMILY SSF49367 36 132 9.94E-11 T 29-03-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 THSYN_RS27550 5a67ca67ccd9a647d20f8d3c40626b9c 114 SMART SM00974 36 111 1.6E-6 T 29-03-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding THSYN_RS27550 5a67ca67ccd9a647d20f8d3c40626b9c 114 Pfam PF13455 Meiotically up-regulated gene 113 42 107 4.0E-12 T 29-03-2018 THSYN_RS23360 1366462a818741960d44bed60c937894 205 Pfam PF07603 Protein of unknown function (DUF1566) 44 183 3.5E-9 T 29-03-2018 IPR011460 Protein of unknown function DUF1566 THSYN_RS03350 75acf084b80cbe0829f20f0743238c5c 221 Pfam PF14316 Domain of unknown function (DUF4381) 20 148 2.6E-40 T 29-03-2018 IPR025489 Protein of unknown function (DUF4381 THSYN_RS00165 f77c580dc9d0f8a2c92ec6894cfd453c 181 Pfam PF05685 Putative restriction endonuclease 12 175 7.4E-20 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS00165 f77c580dc9d0f8a2c92ec6894cfd453c 181 SUPERFAMILY SSF52980 5 177 7.51E-27 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS00165 f77c580dc9d0f8a2c92ec6894cfd453c 181 Gene3D G3DSA:3.90.1570.10 2 178 4.0E-27 T 29-03-2018 THSYN_RS06685 6fd1cf7ceee18e7307a4173fb977790f 281 Gene3D G3DSA:2.40.160.20 13 281 2.7E-6 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THSYN_RS02660 3bc0fb63d894d488960fac0a8462e940 406 Pfam PF01963 TraB family 25 238 1.1E-23 T 29-03-2018 IPR002816 Pheromone shutdown, TraB THSYN_RS02660 3bc0fb63d894d488960fac0a8462e940 406 TIGRFAM TIGR00261 traB: TraB family protein 25 400 5.3E-80 T 29-03-2018 IPR005230 Pheromone shutdown, TraB, bacterial/archaeal THSYN_RS17660 b438f0fcfde55f6bfabe34b307c176f5 399 Pfam PF11899 Protein of unknown function (DUF3419) 14 394 7.9E-111 T 29-03-2018 IPR021829 Protein of unknown function DUF3419 THSYN_RS17660 b438f0fcfde55f6bfabe34b307c176f5 399 Gene3D G3DSA:3.40.50.150 9 397 2.3E-8 T 29-03-2018 THSYN_RS09535 548dc717f5a9e664512d50ed1b137649 187 Gene3D G3DSA:1.10.150.80 80 169 5.5E-22 T 29-03-2018 THSYN_RS09535 548dc717f5a9e664512d50ed1b137649 187 SMART SM00341 95 175 4.2E-8 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 THSYN_RS09535 548dc717f5a9e664512d50ed1b137649 187 SUPERFAMILY SSF47819 91 168 1.0E-18 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 THSYN_RS09535 548dc717f5a9e664512d50ed1b137649 187 Pfam PF00570 HRDC domain 99 165 1.8E-19 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 THSYN_RS13925 a843ee16f46bec57c26648ccca37985a 76 Pfam PF04255 Protein of unknown function (DUF433) 10 65 2.5E-21 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS13925 a843ee16f46bec57c26648ccca37985a 76 SUPERFAMILY SSF46689 6 69 5.38E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS13925 a843ee16f46bec57c26648ccca37985a 76 Gene3D G3DSA:1.10.10.10 10 72 7.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS14120 297b7b42f6862f5ab749af69aac0e8e2 89 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 5 81 9.2E-17 T 29-03-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THSYN_RS30330 ede40c8eed695931c6a48053029bd7f5 369 Gene3D G3DSA:1.20.1600.10 106 246 1.1E-8 T 29-03-2018 THSYN_RS30330 ede40c8eed695931c6a48053029bd7f5 369 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 58 288 3.2E-32 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THSYN_RS30330 ede40c8eed695931c6a48053029bd7f5 369 SUPERFAMILY SSF111369 73 292 1.7E-12 T 29-03-2018 THSYN_RS30330 ede40c8eed695931c6a48053029bd7f5 369 Gene3D G3DSA:2.40.50.100 12 102 2.1E-5 T 29-03-2018 THSYN_RS03175 e653a02c0a3df69bd53332a5630bb661 327 Pfam PF04754 Putative transposase, YhgA-like 6 206 1.1E-48 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS03175 e653a02c0a3df69bd53332a5630bb661 327 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 7 273 9.3E-17 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA THSYN_RS32190 dd68ceb6714c83a29957f4ff838c008f 299 Pfam PF01903 CbiX 11 113 6.9E-15 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 THSYN_RS32190 dd68ceb6714c83a29957f4ff838c008f 299 Pfam PF01903 CbiX 139 242 1.5E-16 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 THSYN_RS32190 dd68ceb6714c83a29957f4ff838c008f 299 Gene3D G3DSA:3.40.50.1400 1 108 1.6E-22 T 29-03-2018 THSYN_RS32190 dd68ceb6714c83a29957f4ff838c008f 299 Gene3D G3DSA:3.40.50.1400 109 236 2.4E-22 T 29-03-2018 THSYN_RS32190 dd68ceb6714c83a29957f4ff838c008f 299 SUPERFAMILY SSF53800 4 246 1.39E-39 T 29-03-2018 THSYN_RS20900 2a4cc8abf7da97dc774cf43006fa9050 79 Pfam PF06945 Protein of unknown function (DUF1289) 16 63 7.1E-20 T 29-03-2018 IPR010710 Protein of unknown function DUF1289 THSYN_RS04980 1cdf03d89f88fe4a94b445926ff32bda 321 Gene3D G3DSA:3.60.21.10 3 315 1.3E-30 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS04980 1cdf03d89f88fe4a94b445926ff32bda 321 Pfam PF00149 Calcineurin-like phosphoesterase 5 97 4.4E-9 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THSYN_RS04980 1cdf03d89f88fe4a94b445926ff32bda 321 SUPERFAMILY SSF56300 111 171 9.06E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS04980 1cdf03d89f88fe4a94b445926ff32bda 321 SUPERFAMILY SSF56300 243 276 9.06E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS04980 1cdf03d89f88fe4a94b445926ff32bda 321 SUPERFAMILY SSF56300 1 83 9.06E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS04090 674947e6074b198561213c86ee6195bb 336 PIRSF PIRSF006470 1 330 7.5E-127 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 THSYN_RS04090 674947e6074b198561213c86ee6195bb 336 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 31 285 1.7E-96 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 THSYN_RS04090 674947e6074b198561213c86ee6195bb 336 Gene3D G3DSA:3.40.190.10 151 280 1.7E-5 T 29-03-2018 THSYN_RS04090 674947e6074b198561213c86ee6195bb 336 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 31 313 1.1E-99 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 THSYN_RS04090 674947e6074b198561213c86ee6195bb 336 SUPERFAMILY SSF53850 153 290 2.39E-5 T 29-03-2018 THSYN_RS07665 f261d5edcd1c440c472882c87055d654 135 Pfam PF00816 H-NS histone family 17 111 4.0E-13 T 29-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 THSYN_RS08125 592d586c3c359b332d96859f97ac2e0e 732 TIGRFAM TIGR02165 cas5_6_GSU0054: CRISPR-associated protein GSU0054/csb2, Dpsyc system 4 505 1.1E-84 T 29-03-2018 IPR019089 CRISPR-associated protein, GSU0054 THSYN_RS08125 592d586c3c359b332d96859f97ac2e0e 732 Pfam PF09609 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) 8 504 9.0E-24 T 29-03-2018 IPR019089 CRISPR-associated protein, GSU0054 THSYN_RS26535 3a1df85dc8756545c778ce90c5e959a2 372 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 54 329 3.8E-46 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THSYN_RS30010 66640687a78936bff8543cccf609e2c0 139 Gene3D G3DSA:1.10.760.10 10 112 2.1E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS30010 66640687a78936bff8543cccf609e2c0 139 SUPERFAMILY SSF46626 10 113 1.0E-14 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS30010 66640687a78936bff8543cccf609e2c0 139 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 37 109 5.2E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS26860 f8325477dbb0156570d699166066482f 65 Gene3D G3DSA:3.40.50.1010 1 64 6.8E-7 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS26860 f8325477dbb0156570d699166066482f 65 SUPERFAMILY SSF88723 2 60 6.21E-5 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS04130 dd026ced68691b5b535f7f089691c448 140 Hamap MF_00476 Nickel-responsive regulator [nikR]. 7 137 27.366 T 29-03-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 THSYN_RS04130 dd026ced68691b5b535f7f089691c448 140 Gene3D G3DSA:1.10.1220.10 9 42 4.5E-14 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS04130 dd026ced68691b5b535f7f089691c448 140 Gene3D G3DSA:3.30.70.1150 43 133 1.2E-36 T 29-03-2018 THSYN_RS04130 dd026ced68691b5b535f7f089691c448 140 Pfam PF01402 Ribbon-helix-helix protein, copG family 9 46 5.0E-8 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 THSYN_RS04130 dd026ced68691b5b535f7f089691c448 140 SUPERFAMILY SSF55021 57 135 5.26E-23 T 29-03-2018 THSYN_RS04130 dd026ced68691b5b535f7f089691c448 140 SUPERFAMILY SSF47598 6 52 3.85E-12 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS04130 dd026ced68691b5b535f7f089691c448 140 Pfam PF08753 NikR C terminal nickel binding domain 59 134 1.4E-28 T 29-03-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal THSYN_RS13990 bff93496969cb7f80192001fa52fe1fe 188 SUPERFAMILY SSF47413 7 68 2.11E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS13990 bff93496969cb7f80192001fa52fe1fe 188 Gene3D G3DSA:1.10.260.40 5 73 1.4E-15 T 29-03-2018 THSYN_RS13990 bff93496969cb7f80192001fa52fe1fe 188 Pfam PF01381 Helix-turn-helix 9 63 4.5E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS13990 bff93496969cb7f80192001fa52fe1fe 188 SMART SM00530 8 63 1.1E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS01715 997cd124333deb57b77b7b18cafbf841 289 Gene3D G3DSA:3.90.1580.10 83 287 4.8E-39 T 29-03-2018 THSYN_RS01715 997cd124333deb57b77b7b18cafbf841 289 SUPERFAMILY SSF56436 93 283 3.53E-39 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS01715 997cd124333deb57b77b7b18cafbf841 289 Pfam PF03781 Sulfatase-modifying factor enzyme 1 94 282 1.1E-33 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS30535 22919c3019f9db6a32a15af235a8aa87 209 SUPERFAMILY SSF56672 78 172 2.0E-12 T 29-03-2018 THSYN_RS30535 22919c3019f9db6a32a15af235a8aa87 209 Pfam PF13655 N-terminal domain of reverse transcriptase 17 98 8.4E-30 T 29-03-2018 IPR025960 Reverse transcriptase, N-terminal domain THSYN_RS30535 22919c3019f9db6a32a15af235a8aa87 209 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 113 172 6.7E-10 T 29-03-2018 IPR000477 Reverse transcriptase domain THSYN_RS31295 5f80b9d49a93d8df27dd5540a80afbf0 84 Gene3D G3DSA:4.10.220.20 21 64 9.4E-16 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS31295 5f80b9d49a93d8df27dd5540a80afbf0 84 SUPERFAMILY SSF56918 17 70 3.03E-9 T 29-03-2018 IPR000066 Antenna complex, alpha/beta subunit GO:0016021|GO:0019684|GO:0030077|GO:0045156 THSYN_RS06465 dd8111e42aa6d7310ca8fcbb47dadc1a 528 Pfam PF03050 Transposase IS66 family 219 484 3.8E-43 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS10840 47e5fe1e4fb9dae8696a6985d74db586 733 Pfam PF03235 Protein of unknown function DUF262 73 301 1.5E-18 T 29-03-2018 IPR004919 Domain of unknown function DUF262 THSYN_RS22645 8dba565aa7a20320729b2d83bae694a6 420 Pfam PF03916 Polysulphide reductase, NrfD 43 333 1.9E-56 T 29-03-2018 IPR005614 NrfD family THSYN_RS22645 8dba565aa7a20320729b2d83bae694a6 420 Gene3D G3DSA:1.20.1630.10 39 338 3.5E-44 T 29-03-2018 THSYN_RS09600 d2f8da33f95e815d68163963353d8f4b 151 Pfam PF01724 Domain of unknown function DUF29 6 142 5.8E-46 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS12840 b5ed2b17de855fdc9d424aafcf157f6f 123 Gene3D G3DSA:3.30.450.20 1 43 1.4E-4 T 29-03-2018 THSYN_RS12840 b5ed2b17de855fdc9d424aafcf157f6f 123 Pfam PF07730 Histidine kinase 87 120 2.0E-6 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 THSYN_RS20135 3e6e21914320ed213b7731b7d99a7839 76 SUPERFAMILY SSF46689 3 73 2.51E-22 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS20135 3e6e21914320ed213b7731b7d99a7839 76 Gene3D G3DSA:1.10.10.10 7 70 1.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS20135 3e6e21914320ed213b7731b7d99a7839 76 Pfam PF04255 Protein of unknown function (DUF433) 7 62 1.3E-23 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS02595 719fee3748531d34899d47d2672c714b 269 Gene3D G3DSA:3.40.1800.10 44 123 1.4E-4 T 29-03-2018 THSYN_RS08855 e1cde50d21c1d3a5d9dfe8d4306a5448 71 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 16 60 1.2E-7 T 29-03-2018 IPR008621 Cbb3-type cytochrome oxidase component THSYN_RS05730 79605c583e958f5b6f1e81aaa8f1940b 76 Gene3D G3DSA:1.10.1220.10 1 37 1.5E-7 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS14275 8d6ad4cd5f7e36566685edb621c59fc7 82 Pfam PF03683 Uncharacterised protein family (UPF0175) 8 81 1.9E-25 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS21960 771047a6c37461bd096ac376af4e8c5c 138 SUPERFAMILY SSF88723 1 133 5.33E-32 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS21960 771047a6c37461bd096ac376af4e8c5c 138 Gene3D G3DSA:3.40.50.1010 1 134 6.7E-25 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS21960 771047a6c37461bd096ac376af4e8c5c 138 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 131 10.962 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS21960 771047a6c37461bd096ac376af4e8c5c 138 Pfam PF01850 PIN domain 4 125 6.1E-11 T 29-03-2018 IPR002716 PIN domain THSYN_RS29855 d5bea2b5ce88acb0729a62a89da92721 147 Gene3D G3DSA:1.20.120.520 2 139 8.5E-7 T 29-03-2018 THSYN_RS29855 d5bea2b5ce88acb0729a62a89da92721 147 Pfam PF01814 Hemerythrin HHE cation binding domain 5 136 1.2E-5 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THSYN_RS20450 e1f44c1450bbe14b7870e83d37e62c44 411 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 278 337 4.7E-10 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THSYN_RS20450 e1f44c1450bbe14b7870e83d37e62c44 411 Pfam PF13175 AAA ATPase domain 22 66 1.8E-10 T 29-03-2018 THSYN_RS20450 e1f44c1450bbe14b7870e83d37e62c44 411 SUPERFAMILY SSF52540 230 342 4.09E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS20450 e1f44c1450bbe14b7870e83d37e62c44 411 SUPERFAMILY SSF52540 22 176 4.09E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS20450 e1f44c1450bbe14b7870e83d37e62c44 411 Gene3D G3DSA:3.40.50.300 22 345 6.8E-25 T 29-03-2018 THSYN_RS23435 71a1a14746504fa4a67a5b073dfa5fb3 128 SUPERFAMILY SSF117991 44 128 4.84E-21 T 29-03-2018 IPR027471 YbeD-like domain THSYN_RS23435 71a1a14746504fa4a67a5b073dfa5fb3 128 Gene3D G3DSA:3.30.70.260 44 128 1.7E-24 T 29-03-2018 THSYN_RS23435 71a1a14746504fa4a67a5b073dfa5fb3 128 Pfam PF04359 Protein of unknown function (DUF493) 50 128 1.9E-25 T 29-03-2018 IPR007454 Uncharacterised protein family UPF0250 THSYN_RS04075 44f807ba174d52bcad3f438cb03d2838 248 SUPERFAMILY SSF52540 24 237 2.32E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS04075 44f807ba174d52bcad3f438cb03d2838 248 Pfam PF02224 Cytidylate kinase 26 235 2.5E-66 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 THSYN_RS04075 44f807ba174d52bcad3f438cb03d2838 248 Hamap MF_00238 Cytidylate kinase [cmk]. 24 238 31.013 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 THSYN_RS04075 44f807ba174d52bcad3f438cb03d2838 248 Gene3D G3DSA:3.40.50.300 22 238 4.6E-45 T 29-03-2018 THSYN_RS04075 44f807ba174d52bcad3f438cb03d2838 248 TIGRFAM TIGR00017 cmk: cytidylate kinase 24 233 2.4E-66 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 THSYN_RS26805 4dda2829b41a1f831ccdd5990aec5f70 257 SUPERFAMILY SSF53448 1 256 4.77E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS26805 4dda2829b41a1f831ccdd5990aec5f70 257 Gene3D G3DSA:3.90.550.10 1 257 5.2E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases THSYN_RS26805 4dda2829b41a1f831ccdd5990aec5f70 257 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 256 8.0E-142 T 29-03-2018 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 THSYN_RS26805 4dda2829b41a1f831ccdd5990aec5f70 257 Pfam PF00483 Nucleotidyl transferase 2 211 6.4E-15 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THSYN_RS06815 992fd49d8f2707119044d6711ace3726 258 SUPERFAMILY SSF51735 2 220 1.2E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain THSYN_RS06815 992fd49d8f2707119044d6711ace3726 258 Gene3D G3DSA:3.40.50.720 1 220 1.1E-32 T 29-03-2018 THSYN_RS06815 992fd49d8f2707119044d6711ace3726 258 Pfam PF01370 NAD dependent epimerase/dehydratase family 1 163 3.6E-22 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THSYN_RS18910 425035ae308868111f11166c8f82f3d4 250 Pfam PF11769 Protein of unknown function (DUF3313) 18 237 7.2E-48 T 29-03-2018 IPR021747 Protein of unknown function DUF3313 THSYN_RS30860 1f4a880e81a84a283c39f1c61046866c 88 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 75 5.1E-14 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS04125 fc441ffd7e2bda5878c355c7281f7d3a 391 Pfam PF01594 AI-2E family transporter 16 346 4.6E-44 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like THSYN_RS28060 98d0da7a25141ca6003738d1d6e89e1f 66 Pfam PF10047 Protein of unknown function (DUF2281) 6 40 9.0E-8 T 29-03-2018 IPR018739 Domain of unknown function DUF2281 THSYN_RS05390 530aeaff078061fe4b596d74c42a69b1 60 Gene3D G3DSA:3.40.50.1010 1 59 4.2E-10 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS05390 530aeaff078061fe4b596d74c42a69b1 60 Pfam PF01850 PIN domain 2 50 1.8E-5 T 29-03-2018 IPR002716 PIN domain THSYN_RS05390 530aeaff078061fe4b596d74c42a69b1 60 SUPERFAMILY SSF88723 2 51 1.18E-9 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS16515 3e9213df43ac605704de0647e387f806 298 Pfam PF03692 Putative zinc- or iron-chelating domain 29 125 8.1E-10 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein THSYN_RS18670 adf4cc0e289f978683aee5255be6c95b 147 SUPERFAMILY SSF88723 2 127 3.92E-9 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS18670 adf4cc0e289f978683aee5255be6c95b 147 Pfam PF01850 PIN domain 4 122 4.2E-5 T 29-03-2018 IPR002716 PIN domain THSYN_RS18670 adf4cc0e289f978683aee5255be6c95b 147 Gene3D G3DSA:3.40.50.1010 1 140 5.9E-13 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS20465 afc1d1f794ee0dc46588fa93ea3dfb7c 123 Pfam PF13366 PD-(D/E)XK nuclease superfamily 10 118 9.7E-37 T 29-03-2018 IPR026350 GxxExxY protein THSYN_RS20465 afc1d1f794ee0dc46588fa93ea3dfb7c 123 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 9 122 6.0E-41 T 29-03-2018 IPR026350 GxxExxY protein THSYN_RS24400 a4abb4aafb50169d57e461d72e0d74c4 448 SUPERFAMILY SSF53098 310 383 9.86E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS24400 a4abb4aafb50169d57e461d72e0d74c4 448 Pfam PF13701 Transposase DDE domain group 1 12 446 7.5E-30 T 29-03-2018 IPR025668 Transposase DDE domain THSYN_RS24400 a4abb4aafb50169d57e461d72e0d74c4 448 Gene3D G3DSA:3.90.350.10 114 361 1.2E-5 T 29-03-2018 IPR014736 Transposase, Tn5-like, core THSYN_RS17565 f2fe2300b1d173a9b269f9ce7843fe5d 338 Pfam PF02371 Transposase IS116/IS110/IS902 family 213 298 3.0E-14 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THSYN_RS17565 f2fe2300b1d173a9b269f9ce7843fe5d 338 Pfam PF01548 Transposase 6 145 2.3E-14 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THSYN_RS03030 1fcaa7dad61b92c46a5813c064b37f79 101 SUPERFAMILY SSF54637 7 93 1.63E-8 T 29-03-2018 IPR029069 HotDog domain THSYN_RS03030 1fcaa7dad61b92c46a5813c064b37f79 101 Gene3D G3DSA:3.10.129.10 2 100 1.1E-9 T 29-03-2018 THSYN_RS13380 28b80308a613359fd7f1c015e7d51548 103 SUPERFAMILY SSF143880 2 82 2.62E-22 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS13380 28b80308a613359fd7f1c015e7d51548 103 Gene3D G3DSA:3.30.2020.10 1 80 7.4E-23 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS13380 28b80308a613359fd7f1c015e7d51548 103 Pfam PF10387 Protein of unknown function (DUF2442) 5 79 1.1E-20 T 29-03-2018 IPR018841 Protein of unknown function DUF2442 THSYN_RS08145 d14bf5c5f6699c5ae4804eee8dc264cc 280 Pfam PF02661 Fic/DOC family 98 199 3.4E-9 T 29-03-2018 IPR003812 Fido domain THSYN_RS08145 d14bf5c5f6699c5ae4804eee8dc264cc 280 Gene3D G3DSA:1.10.3290.10 2 261 1.9E-29 T 29-03-2018 IPR003812 Fido domain THSYN_RS08145 d14bf5c5f6699c5ae4804eee8dc264cc 280 SUPERFAMILY SSF140931 88 251 6.54E-25 T 29-03-2018 IPR003812 Fido domain THSYN_RS04175 71e461db17d2fffd9237f92c73ce3fa2 59 Pfam PF13396 Phospholipase_D-nuclease N-terminal 15 57 1.3E-11 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal THSYN_RS13405 bc4e439ad065dfd157590c580fe81219 131 SUPERFAMILY SSF53146 1 103 1.2E-18 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THSYN_RS13405 bc4e439ad065dfd157590c580fe81219 131 Gene3D G3DSA:3.30.420.130 1 122 2.1E-18 T 29-03-2018 THSYN_RS13405 bc4e439ad065dfd157590c580fe81219 131 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 11 100 1.4E-5 T 29-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis THSYN_RS13390 81874f7ddf096fb4a06a4d070c109a9a 753 Gene3D G3DSA:3.40.50.410 545 753 7.3E-23 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS13390 81874f7ddf096fb4a06a4d070c109a9a 753 Pfam PF00092 von Willebrand factor type A domain 565 716 1.8E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS13390 81874f7ddf096fb4a06a4d070c109a9a 753 SUPERFAMILY SSF53300 563 748 5.49E-22 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS13390 81874f7ddf096fb4a06a4d070c109a9a 753 SMART SM00327 562 752 3.0E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS10000 95a8e471437525eeee6a38def97a88e3 832 Gene3D G3DSA:2.60.500.10 378 452 1.8E-12 T 29-03-2018 THSYN_RS10000 95a8e471437525eeee6a38def97a88e3 832 Gene3D G3DSA:2.60.120.640 174 276 1.4E-7 T 29-03-2018 THSYN_RS10000 95a8e471437525eeee6a38def97a88e3 832 Gene3D G3DSA:2.60.120.640 577 640 4.0E-4 T 29-03-2018 THSYN_RS10000 95a8e471437525eeee6a38def97a88e3 832 Gene3D G3DSA:2.60.40.10 453 542 1.5E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS10000 95a8e471437525eeee6a38def97a88e3 832 Gene3D G3DSA:2.60.40.10 641 730 9.8E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold THSYN_RS28110 6cb5c60c7a3526a48161cce060bd5e6f 179 Gene3D G3DSA:1.20.120.580 1 102 1.1E-10 T 29-03-2018 IPR008201 Protein of unknown function DUF86 THSYN_RS28110 6cb5c60c7a3526a48161cce060bd5e6f 179 Pfam PF01934 Protein of unknown function DUF86 17 101 2.0E-8 T 29-03-2018 IPR008201 Protein of unknown function DUF86 THSYN_RS09150 071d32b3b6c0c54b970c7981d6348773 183 Gene3D G3DSA:1.20.120.520 1 182 2.0E-16 T 29-03-2018 THSYN_RS09150 071d32b3b6c0c54b970c7981d6348773 183 Pfam PF01814 Hemerythrin HHE cation binding domain 7 138 9.0E-12 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THSYN_RS17230 1eda87aa1d4ec6f392cb4972d0aabd09 187 Gene3D G3DSA:3.40.50.150 1 147 4.4E-8 T 29-03-2018 THSYN_RS17230 1eda87aa1d4ec6f392cb4972d0aabd09 187 SUPERFAMILY SSF53335 1 143 4.84E-10 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THSYN_RS24145 bf9ab051c218d5671e8bad57be2a9740 237 Gene3D G3DSA:1.20.1380.10 125 221 3.1E-9 T 29-03-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 THSYN_RS18565 bbeae4c3a83692638c437d69c39a01a2 59 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 1 51 4.9E-19 T 29-03-2018 IPR010260 DNA-binding transcriptional activator AlpA THSYN_RS18565 bbeae4c3a83692638c437d69c39a01a2 59 SUPERFAMILY SSF46955 3 53 2.56E-6 T 29-03-2018 IPR009061 Putative DNA-binding domain THSYN_RS18565 bbeae4c3a83692638c437d69c39a01a2 59 Gene3D G3DSA:1.10.10.10 5 57 4.8E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS17485 2af9eaf1a1b46f525b1b239248699ffb 220 Pfam PF09849 Uncharacterized protein conserved in bacteria (DUF2076) 1 189 4.1E-53 T 29-03-2018 IPR018648 Protein of unknown function DUF2076 THSYN_RS22190 c78af7548332378d4f951b88388673ed 185 SUPERFAMILY SSF58113 16 117 3.27E-5 T 29-03-2018 THSYN_RS22190 c78af7548332378d4f951b88388673ed 185 Gene3D G3DSA:1.20.120.20 11 136 2.1E-4 T 29-03-2018 THSYN_RS22190 c78af7548332378d4f951b88388673ed 185 Pfam PF07295 Zinc-ribbon containing domain 32 175 3.7E-49 T 29-03-2018 IPR009912 Zinc-ribbon containing domain THSYN_RS14385 08b4ff8da9295f47b6ed2426684b2f06 77 PIRSF PIRSF037031 1 77 3.8E-28 T 29-03-2018 IPR005243 Redox-active disulphide protein 2 THSYN_RS14385 08b4ff8da9295f47b6ed2426684b2f06 77 Gene3D G3DSA:3.40.30.10 1 77 2.0E-13 T 29-03-2018 THSYN_RS14385 08b4ff8da9295f47b6ed2426684b2f06 77 SUPERFAMILY SSF52833 1 76 1.73E-19 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS14385 08b4ff8da9295f47b6ed2426684b2f06 77 Pfam PF13192 Thioredoxin domain 4 76 6.2E-25 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS15610 816ccdd04db6de5b731f075990dd1245 63 ProSitePatterns PS00018 EF-hand calcium-binding domain. 14 26 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site THSYN_RS03660 9c1af763fc2ba5c1df7ae9dcd7db7f39 220 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 185 204 0.0027 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS14600 d2d64f7b77c1db86343550a6a423e67c 791 Pfam PF05593 RHS Repeat 588 620 1.4E-6 T 29-03-2018 IPR031325 RHS repeat THSYN_RS14600 d2d64f7b77c1db86343550a6a423e67c 791 Gene3D G3DSA:2.130.10.10 112 414 0.016 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THSYN_RS14600 d2d64f7b77c1db86343550a6a423e67c 791 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 588 620 5.1E-7 T 29-03-2018 IPR006530 YD repeat THSYN_RS14600 d2d64f7b77c1db86343550a6a423e67c 791 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 372 411 1.3E-6 T 29-03-2018 IPR006530 YD repeat THSYN_RS14600 d2d64f7b77c1db86343550a6a423e67c 791 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 351 384 3.3E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS14600 d2d64f7b77c1db86343550a6a423e67c 791 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 226 264 5.3E-5 T 29-03-2018 IPR006530 YD repeat THSYN_RS30655 0d8e8157223861d93163e7481920cc1c 347 Gene3D G3DSA:3.40.630.30 2 342 9.7E-11 T 29-03-2018 THSYN_RS30655 0d8e8157223861d93163e7481920cc1c 347 SUPERFAMILY SSF55729 11 115 1.14E-9 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS04555 f9f45111036125efceb98daecb40d571 89 Pfam PF03683 Uncharacterised protein family (UPF0175) 8 77 1.1E-11 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS28980 7bf609b2707ae1944b4b5dbca2d7a630 382 Pfam PF13477 Glycosyl transferase 4-like 8 143 5.3E-17 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS28980 7bf609b2707ae1944b4b5dbca2d7a630 382 Pfam PF00534 Glycosyl transferases group 1 190 351 1.3E-27 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS28980 7bf609b2707ae1944b4b5dbca2d7a630 382 SUPERFAMILY SSF53756 21 374 7.71E-67 T 29-03-2018 THSYN_RS28980 7bf609b2707ae1944b4b5dbca2d7a630 382 Gene3D G3DSA:3.40.50.2000 5 190 8.7E-18 T 29-03-2018 THSYN_RS28980 7bf609b2707ae1944b4b5dbca2d7a630 382 Gene3D G3DSA:3.40.50.2000 191 359 1.1E-41 T 29-03-2018 THSYN_RS26490 98bcb551723cae09d0ed91c80e139f46 140 Pfam PF03061 Thioesterase superfamily 31 104 2.5E-16 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 THSYN_RS26490 98bcb551723cae09d0ed91c80e139f46 140 SUPERFAMILY SSF54637 14 135 3.27E-34 T 29-03-2018 IPR029069 HotDog domain THSYN_RS26490 98bcb551723cae09d0ed91c80e139f46 140 Gene3D G3DSA:3.10.129.10 1 138 5.1E-34 T 29-03-2018 THSYN_RS26940 1223aa17285092ea499268f122f5eadc 167 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 22 155 2.0E-27 T 29-03-2018 IPR007359 Positive regulator of sigma(E), RseC/MucC THSYN_RS26940 1223aa17285092ea499268f122f5eadc 167 PIRSF PIRSF004923 15 164 1.4E-25 T 29-03-2018 IPR026268 Protein RseC THSYN_RS03355 77690dab494456afc44ec1e76c75ad7c 327 Pfam PF01882 Protein of unknown function DUF58 56 140 2.2E-21 T 29-03-2018 IPR002881 Domain of unknown function DUF58 THSYN_RS03355 77690dab494456afc44ec1e76c75ad7c 327 Gene3D G3DSA:3.40.50.410 68 259 1.7E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS12320 58c6b3dfd406c36c4dea7cd5e25f7e5b 95 Pfam PF13560 Helix-turn-helix domain 14 73 7.3E-9 T 29-03-2018 THSYN_RS12320 58c6b3dfd406c36c4dea7cd5e25f7e5b 95 Gene3D G3DSA:1.10.260.40 4 84 1.7E-10 T 29-03-2018 THSYN_RS12320 58c6b3dfd406c36c4dea7cd5e25f7e5b 95 SUPERFAMILY SSF47413 5 67 2.02E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS19640 6cad69096a6bfec37f076071ba5993c2 296 Hamap MF_00188 Protease HtpX [htpX]. 1 294 24.099 T 29-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 THSYN_RS19640 6cad69096a6bfec37f076071ba5993c2 296 Pfam PF01435 Peptidase family M48 80 293 8.0E-38 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THSYN_RS19640 6cad69096a6bfec37f076071ba5993c2 296 Gene3D G3DSA:3.30.2010.10 69 162 2.4E-20 T 29-03-2018 THSYN_RS22495 12baab8377f963289cab408f1a7e97b6 74 Pfam PF09720 Putative addiction module component 13 65 1.3E-10 T 29-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THSYN_RS22725 2b23762f8d29f52d2c2b4b53a858604e 305 Gene3D G3DSA:3.20.20.370 25 302 3.9E-42 T 29-03-2018 THSYN_RS22725 2b23762f8d29f52d2c2b4b53a858604e 305 SUPERFAMILY SSF88713 182 282 5.56E-32 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS22725 2b23762f8d29f52d2c2b4b53a858604e 305 SUPERFAMILY SSF88713 37 104 5.56E-32 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS22725 2b23762f8d29f52d2c2b4b53a858604e 305 Pfam PF01522 Polysaccharide deacetylase 60 262 5.9E-27 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 THSYN_RS31565 112af7cd0058ebac91ca7710bacf66fb 149 Pfam PF08388 Group II intron, maturase-specific domain 50 113 4.4E-5 T 29-03-2018 IPR013597 Group II intron, maturase-specific THSYN_RS19995 92f0c4118acf30e33f980ee6de7057a6 150 Pfam PF01724 Domain of unknown function DUF29 4 141 1.3E-45 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS08725 4809d97b73f08b70873e1dd903ce4501 303 Gene3D G3DSA:3.40.50.300 115 302 2.2E-15 T 29-03-2018 THSYN_RS08725 4809d97b73f08b70873e1dd903ce4501 303 SUPERFAMILY SSF53795 115 269 1.37E-14 T 29-03-2018 THSYN_RS08725 4809d97b73f08b70873e1dd903ce4501 303 TIGRFAM TIGR04352 HprK_rel_A: HprK-related kinase A 22 299 8.0E-109 T 29-03-2018 IPR027600 HprK-related kinase A THSYN_RS04655 64ff8d3d0ce8d83a5159a5febefd564b 259 Gene3D G3DSA:3.90.1570.10 19 173 6.3E-24 T 29-03-2018 THSYN_RS04655 64ff8d3d0ce8d83a5159a5febefd564b 259 SUPERFAMILY SSF52980 6 167 1.34E-30 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS04655 64ff8d3d0ce8d83a5159a5febefd564b 259 Pfam PF05685 Putative restriction endonuclease 48 156 5.2E-17 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS12335 5f2f0411779e4b4bc409bb1b406f53a1 643 Pfam PF03641 Possible lysine decarboxylase 503 632 5.4E-9 T 29-03-2018 IPR031100 LOG family THSYN_RS12335 5f2f0411779e4b4bc409bb1b406f53a1 643 Gene3D G3DSA:3.40.50.450 433 642 1.5E-20 T 29-03-2018 THSYN_RS12335 5f2f0411779e4b4bc409bb1b406f53a1 643 SUPERFAMILY SSF102405 456 635 1.33E-16 T 29-03-2018 THSYN_RS09835 5e608dddfa9665911b85fd2cf8d10357 357 Pfam PF00912 Transglycosylase 49 137 2.8E-8 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 THSYN_RS09835 5e608dddfa9665911b85fd2cf8d10357 357 Gene3D G3DSA:1.10.3810.10 34 213 2.7E-12 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 THSYN_RS09835 5e608dddfa9665911b85fd2cf8d10357 357 Gene3D G3DSA:3.40.710.10 230 347 1.5E-4 T 29-03-2018 THSYN_RS10250 f21b4423e3c52658a86aa08d23df8d79 162 Pfam PF06271 RDD family 21 150 1.1E-22 T 29-03-2018 IPR010432 RDD THSYN_RS27465 a3ff050b784d599ae7a20034a183e937 76 SUPERFAMILY SSF56024 8 55 2.24E-8 T 29-03-2018 THSYN_RS27465 a3ff050b784d599ae7a20034a183e937 76 Gene3D G3DSA:3.30.870.10 2 75 5.7E-9 T 29-03-2018 THSYN_RS04565 71c0d51ea3aca7516dc308fe62ad5d05 169 Pfam PF10504 Protein of unknown function (DUF2452) 15 158 4.0E-47 T 29-03-2018 IPR019534 Protein of unknown function DUF2452 THSYN_RS19810 c5ab97c04c1b3023942cb90141b80874 105 Gene3D G3DSA:1.20.5.620 5 46 0.0011 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain THSYN_RS19785 3ff899ac157c2dc794ee23b23c759e1e 155 SMART SM01118 2 149 1.9E-25 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 THSYN_RS19785 3ff899ac157c2dc794ee23b23c759e1e 155 Pfam PF01928 CYTH domain 3 150 5.8E-13 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 THSYN_RS19785 3ff899ac157c2dc794ee23b23c759e1e 155 PIRSF PIRSF016487 1 155 1.0E-57 T 29-03-2018 IPR012042 Inorganic triphosphatase NeuTTM/CthTTM-like THSYN_RS19785 3ff899ac157c2dc794ee23b23c759e1e 155 SUPERFAMILY SSF55154 1 149 5.07E-40 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 THSYN_RS19785 3ff899ac157c2dc794ee23b23c759e1e 155 Gene3D G3DSA:2.40.320.10 1 152 4.9E-41 T 29-03-2018 THSYN_RS14635 129cd4adb00c714875573b9cdcf68478 89 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 19 83 1.3E-9 T 29-03-2018 IPR008792 Coenzyme PQQ synthesis D THSYN_RS07505 f5db5c3978bf0c986b568142173f6b0a 76 Pfam PF10047 Protein of unknown function (DUF2281) 7 39 8.0E-7 T 29-03-2018 IPR018739 Domain of unknown function DUF2281 THSYN_RS28525 da95c759d033020b8b8ae7a7e0b1249f 127 SUPERFAMILY SSF81301 22 127 1.59E-19 T 29-03-2018 THSYN_RS28525 da95c759d033020b8b8ae7a7e0b1249f 127 Pfam PF01909 Nucleotidyltransferase domain 28 100 2.1E-9 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS28525 da95c759d033020b8b8ae7a7e0b1249f 127 Gene3D G3DSA:3.30.460.10 18 127 3.3E-18 T 29-03-2018 THSYN_RS29190 61a0ecdd49d9b70f6cd2c4e36084042a 129 Pfam PF03899 ATP synthase I chain 6 101 2.7E-14 T 29-03-2018 IPR005598 ATP synthase protein I THSYN_RS06440 739b2afa4416a71803009af2a28368eb 615 SUPERFAMILY SSF56436 188 313 1.06E-26 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS06440 739b2afa4416a71803009af2a28368eb 615 SUPERFAMILY SSF56436 100 157 1.06E-26 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS06440 739b2afa4416a71803009af2a28368eb 615 Pfam PF03781 Sulfatase-modifying factor enzyme 1 389 612 1.2E-52 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS06440 739b2afa4416a71803009af2a28368eb 615 Pfam PF03781 Sulfatase-modifying factor enzyme 1 107 313 1.2E-20 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS06440 739b2afa4416a71803009af2a28368eb 615 Gene3D G3DSA:3.90.1580.10 443 615 1.3E-50 T 29-03-2018 THSYN_RS06440 739b2afa4416a71803009af2a28368eb 615 Gene3D G3DSA:3.90.1580.10 376 442 2.1E-15 T 29-03-2018 THSYN_RS06440 739b2afa4416a71803009af2a28368eb 615 Gene3D G3DSA:3.90.1580.10 102 310 2.1E-22 T 29-03-2018 THSYN_RS06440 739b2afa4416a71803009af2a28368eb 615 SUPERFAMILY SSF56436 387 614 8.71E-74 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS03915 1f67e063254a961768584c456217f7c6 78 Pfam PF16277 Domain of unknown function (DUF4926) 7 66 2.2E-21 T 29-03-2018 IPR032568 Protein of unknown function DUF4926 THSYN_RS08265 af59075287180361a8c2ffebe6656b91 274 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 38 145 7.3E-6 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 THSYN_RS08265 af59075287180361a8c2ffebe6656b91 274 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 187 271 4.7E-10 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 THSYN_RS08265 af59075287180361a8c2ffebe6656b91 274 Gene3D G3DSA:3.30.559.10 2 274 5.6E-28 T 29-03-2018 THSYN_RS08265 af59075287180361a8c2ffebe6656b91 274 SUPERFAMILY SSF52777 183 271 7.56E-26 T 29-03-2018 THSYN_RS08265 af59075287180361a8c2ffebe6656b91 274 SUPERFAMILY SSF52777 38 153 7.56E-26 T 29-03-2018 THSYN_RS25455 f5d8b892e1647f22e0e5f543e526ed21 418 Gene3D G3DSA:1.25.40.10 55 265 8.6E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS25455 f5d8b892e1647f22e0e5f543e526ed21 418 Gene3D G3DSA:2.60.120.260 266 418 2.3E-11 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS25455 f5d8b892e1647f22e0e5f543e526ed21 418 SUPERFAMILY SSF48452 57 160 1.41E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS25775 fcef3980f2c475b81f3a81f28fd61462 363 SUPERFAMILY SSF101478 95 355 3.53E-34 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 THSYN_RS25775 fcef3980f2c475b81f3a81f28fd61462 363 SUPERFAMILY SSF101478 5 56 3.53E-34 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 THSYN_RS25775 fcef3980f2c475b81f3a81f28fd61462 363 Gene3D G3DSA:1.10.4080.10 1 362 4.0E-56 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 THSYN_RS25775 fcef3980f2c475b81f3a81f28fd61462 363 Pfam PF03747 ADP-ribosylglycohydrolase 12 336 3.3E-51 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 THSYN_RS11165 e691fa40412d19a4796a14d2dfe84ac1 224 Pfam PF01863 Protein of unknown function DUF45 8 210 5.2E-48 T 29-03-2018 IPR002725 Protein of unknown function DUF45 THSYN_RS04350 6e365b4fd0cc4a53d6969eff675d2013 199 SUPERFAMILY SSF50341 58 193 5.36E-28 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS04350 6e365b4fd0cc4a53d6969eff675d2013 199 Gene3D G3DSA:2.30.30.40 142 186 3.4E-5 T 29-03-2018 THSYN_RS04350 6e365b4fd0cc4a53d6969eff675d2013 199 Pfam PF01584 CheW-like domain 59 192 3.2E-23 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS04350 6e365b4fd0cc4a53d6969eff675d2013 199 Gene3D G3DSA:2.40.50.180 76 141 1.9E-12 T 29-03-2018 THSYN_RS04350 6e365b4fd0cc4a53d6969eff675d2013 199 SMART SM00260 55 192 1.4E-14 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THSYN_RS13205 c051b9538b8d2aa5cf147eaa45c667ca 191 SUPERFAMILY SSF52980 12 187 6.97E-28 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS13205 c051b9538b8d2aa5cf147eaa45c667ca 191 Gene3D G3DSA:3.90.1570.10 2 187 5.3E-26 T 29-03-2018 THSYN_RS13205 c051b9538b8d2aa5cf147eaa45c667ca 191 Pfam PF05685 Putative restriction endonuclease 12 173 1.6E-19 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS02140 17b490e15908d68f52e308e5cf02baa5 136 Pfam PF09086 Domain of unknown function (DUF1924) 41 133 4.5E-38 T 29-03-2018 IPR015170 Protein of unknown function DUF1924 THSYN_RS02140 17b490e15908d68f52e308e5cf02baa5 136 Gene3D G3DSA:1.10.760.10 25 136 1.9E-14 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS02140 17b490e15908d68f52e308e5cf02baa5 136 SUPERFAMILY SSF46626 31 135 1.95E-28 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 THSYN_RS11200 76abd35a911a7f292bd5749b78e24646 362 Pfam PF10123 Mu-like prophage I protein 22 318 1.7E-66 T 29-03-2018 IPR012106 Protease, Mu phage/prophage I type THSYN_RS11200 76abd35a911a7f292bd5749b78e24646 362 PIRSF PIRSF016624 7 346 4.4E-53 T 29-03-2018 IPR012106 Protease, Mu phage/prophage I type THSYN_RS20650 58a1cd81e31f94a86709efd256597c84 392 Gene3D G3DSA:1.10.645.10 195 384 7.8E-17 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS20650 58a1cd81e31f94a86709efd256597c84 392 Gene3D G3DSA:1.10.645.10 3 135 6.8E-10 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS20650 58a1cd81e31f94a86709efd256597c84 392 SUPERFAMILY SSF56762 15 381 2.13E-35 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS09220 f845daa4df2a8d8ed7819cd0c0a35cb3 389 Pfam PF13635 Domain of unknown function (DUF4143) 180 334 2.9E-19 T 29-03-2018 IPR025420 Domain of unknown function DUF4143 THSYN_RS09220 f845daa4df2a8d8ed7819cd0c0a35cb3 389 Gene3D G3DSA:1.10.10.10 184 255 0.0028 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS09220 f845daa4df2a8d8ed7819cd0c0a35cb3 389 SUPERFAMILY SSF52540 4 183 2.87E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS09220 f845daa4df2a8d8ed7819cd0c0a35cb3 389 Pfam PF13173 AAA domain 22 140 7.1E-18 T 29-03-2018 THSYN_RS09220 f845daa4df2a8d8ed7819cd0c0a35cb3 389 Gene3D G3DSA:3.40.50.300 2 144 3.7E-6 T 29-03-2018 THSYN_RS11895 5484b13b051c574d3653896d03127de0 118 Pfam PF05120 Gas vesicle protein G 4 81 8.4E-21 T 29-03-2018 IPR007804 Gas vesicle protein GvpG THSYN_RS03815 35c1aba690e1eb6410b05c8f9b61c3eb 146 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THSYN_RS03815 35c1aba690e1eb6410b05c8f9b61c3eb 146 PRINTS PR00502 NUDIX hydrolase family signature 37 51 1.8E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THSYN_RS03815 35c1aba690e1eb6410b05c8f9b61c3eb 146 PRINTS PR00502 NUDIX hydrolase family signature 51 66 1.8E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THSYN_RS03815 35c1aba690e1eb6410b05c8f9b61c3eb 146 Pfam PF00293 NUDIX domain 12 129 5.4E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THSYN_RS03815 35c1aba690e1eb6410b05c8f9b61c3eb 146 Gene3D G3DSA:3.90.79.10 3 135 3.1E-29 T 29-03-2018 THSYN_RS03815 35c1aba690e1eb6410b05c8f9b61c3eb 146 SUPERFAMILY SSF55811 3 135 2.84E-26 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 THSYN_RS04540 7aa6ffe68434bc956beb96dda9968bb8 542 SUPERFAMILY SSF56436 25 243 8.95E-59 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS04540 7aa6ffe68434bc956beb96dda9968bb8 542 Pfam PF03781 Sulfatase-modifying factor enzyme 1 25 243 1.6E-51 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS04540 7aa6ffe68434bc956beb96dda9968bb8 542 Pfam PF03781 Sulfatase-modifying factor enzyme 1 292 540 1.6E-31 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THSYN_RS04540 7aa6ffe68434bc956beb96dda9968bb8 542 Gene3D G3DSA:3.90.1580.10 8 76 2.3E-11 T 29-03-2018 THSYN_RS04540 7aa6ffe68434bc956beb96dda9968bb8 542 Gene3D G3DSA:3.90.1580.10 77 256 6.7E-46 T 29-03-2018 THSYN_RS04540 7aa6ffe68434bc956beb96dda9968bb8 542 Gene3D G3DSA:3.90.1580.10 277 542 2.3E-31 T 29-03-2018 THSYN_RS04540 7aa6ffe68434bc956beb96dda9968bb8 542 SUPERFAMILY SSF56436 441 541 8.01E-34 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS04540 7aa6ffe68434bc956beb96dda9968bb8 542 SUPERFAMILY SSF56436 288 398 8.01E-34 T 29-03-2018 IPR016187 C-type lectin fold THSYN_RS24815 702c497b74a5e659d041e29b9074a9fb 203 Pfam PF01618 MotA/TolQ/ExbB proton channel family 64 183 8.2E-34 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 THSYN_RS32715 3ecb2d734ac5c15e8860b178a3d4b004 390 SUPERFAMILY SSF55486 228 336 1.47E-5 T 29-03-2018 THSYN_RS27075 40a42549ec7b4267fce6cc00b77471c3 104 Gene3D G3DSA:1.10.260.40 22 100 2.2E-11 T 29-03-2018 THSYN_RS27075 40a42549ec7b4267fce6cc00b77471c3 104 SUPERFAMILY SSF47413 44 87 3.49E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THSYN_RS27075 40a42549ec7b4267fce6cc00b77471c3 104 Pfam PF13560 Helix-turn-helix domain 44 84 8.6E-8 T 29-03-2018 THSYN_RS27075 40a42549ec7b4267fce6cc00b77471c3 104 SMART SM00530 43 96 0.0068 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THSYN_RS29390 ed488926640a1098f2aa48bab20562e8 83 Gene3D G3DSA:2.40.10.220 4 83 3.0E-6 T 29-03-2018 THSYN_RS06930 42b8944bda3d05faf288a5fc8b8f425c 440 SUPERFAMILY SSF101960 25 435 4.97E-102 T 29-03-2018 THSYN_RS06930 42b8944bda3d05faf288a5fc8b8f425c 440 Pfam PF01458 Uncharacterized protein family (UPF0051) 186 409 1.1E-70 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 THSYN_RS06930 42b8944bda3d05faf288a5fc8b8f425c 440 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 150 425 5.5E-81 T 29-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 THSYN_RS18335 a047ebb4f6623ebf038e69be27b5226d 496 Gene3D G3DSA:3.40.720.10 2 233 6.7E-55 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS18335 a047ebb4f6623ebf038e69be27b5226d 496 Gene3D G3DSA:3.40.720.10 234 371 1.3E-26 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THSYN_RS18335 a047ebb4f6623ebf038e69be27b5226d 496 Pfam PF00884 Sulfatase 6 335 1.3E-60 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THSYN_RS18335 a047ebb4f6623ebf038e69be27b5226d 496 SUPERFAMILY SSF53649 2 439 2.33E-120 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THSYN_RS18335 a047ebb4f6623ebf038e69be27b5226d 496 Gene3D G3DSA:3.30.1120.10 372 464 1.4E-17 T 29-03-2018 THSYN_RS03905 c644790731260185fec7d44b3b834b8d 548 Gene3D G3DSA:1.10.10.10 467 531 9.4E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS19495 e7c54f9ce4bf5de0af0213eae0e6a20c 218 Gene3D G3DSA:2.60.40.380 6 90 1.0E-6 T 29-03-2018 THSYN_RS19495 e7c54f9ce4bf5de0af0213eae0e6a20c 218 SUPERFAMILY SSF49363 12 71 7.46E-10 T 29-03-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 THSYN_RS21090 95739760c3693af8955ee33648327e04 443 Pfam PF14281 PD-(D/E)XK nuclease superfamily 29 199 1.4E-34 T 29-03-2018 IPR029470 PD-(D/E)XK nuclease superfamily 4 THSYN_RS10485 8c53f2b86e9abfd9a7ea4519689a3016 301 Gene3D G3DSA:3.60.130.10 33 297 4.4E-27 T 29-03-2018 THSYN_RS10485 8c53f2b86e9abfd9a7ea4519689a3016 301 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 98 292 2.6E-14 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 THSYN_RS10485 8c53f2b86e9abfd9a7ea4519689a3016 301 SUPERFAMILY SSF51197 34 296 4.21E-43 T 29-03-2018 THSYN_RS23535 61816542a7e0e2173616650b93d8a41d 75 Pfam PF13711 Domain of unknown function (DUF4160) 17 71 6.3E-11 T 29-03-2018 IPR025427 Protein of unknown function DUF4160 THSYN_RS10815 76c8d091ed1c476971f8ac6c1a9614a5 114 Hamap MF_00529 Nitrogenase-stabilizing/protective protein NifW [nifW]. 4 105 20.641 T 29-03-2018 IPR004893 Nitrogen fixation protein NifW GO:0009399 THSYN_RS10815 76c8d091ed1c476971f8ac6c1a9614a5 114 Pfam PF03206 Nitrogen fixation protein NifW 8 104 2.6E-31 T 29-03-2018 IPR004893 Nitrogen fixation protein NifW GO:0009399 THSYN_RS10815 76c8d091ed1c476971f8ac6c1a9614a5 114 PIRSF PIRSF005790 1 107 8.3E-29 T 29-03-2018 IPR004893 Nitrogen fixation protein NifW GO:0009399 THSYN_RS11765 5d80f756c8ddeb2f7866a3ba1252ad00 200 Pfam PF00043 Glutathione S-transferase, C-terminal domain 109 181 6.8E-9 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal THSYN_RS11765 5d80f756c8ddeb2f7866a3ba1252ad00 200 SUPERFAMILY SSF47616 72 195 1.71E-28 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like THSYN_RS11765 5d80f756c8ddeb2f7866a3ba1252ad00 200 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 77 2.8E-21 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THSYN_RS11765 5d80f756c8ddeb2f7866a3ba1252ad00 200 Gene3D G3DSA:1.20.1050.10 87 199 3.9E-19 T 29-03-2018 THSYN_RS11765 5d80f756c8ddeb2f7866a3ba1252ad00 200 ProSitePatterns PS00195 Glutaredoxin active site. 3 19 - T 29-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 THSYN_RS11765 5d80f756c8ddeb2f7866a3ba1252ad00 200 SUPERFAMILY SSF52833 1 101 9.8E-32 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS11765 5d80f756c8ddeb2f7866a3ba1252ad00 200 Gene3D G3DSA:3.40.30.10 1 86 7.1E-30 T 29-03-2018 THSYN_RS05580 800f45fcc4af563a7ef92af985311345 74 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 3 47 4.9E-14 T 29-03-2018 IPR022453 Zinc finger, MqsA-type THSYN_RS16335 5cc3581cae7435735dd5b8ec2ececc14 138 Gene3D G3DSA:3.40.50.620 28 126 3.6E-7 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THSYN_RS16335 5cc3581cae7435735dd5b8ec2ececc14 138 SUPERFAMILY SSF52402 30 112 7.22E-9 T 29-03-2018 THSYN_RS12250 4084deef1158e91139d03c07bf50c274 66 Pfam PF10049 Protein of unknown function (DUF2283) 2 49 6.2E-9 T 29-03-2018 IPR019270 Protein of unknown function DUF2283 THSYN_RS06035 9da5bb2544b034a06f8f80d14ce08810 139 Gene3D G3DSA:3.10.450.50 8 139 1.2E-12 T 29-03-2018 THSYN_RS06035 9da5bb2544b034a06f8f80d14ce08810 139 Pfam PF02810 SEC-C motif 121 139 2.5E-10 T 29-03-2018 IPR004027 SEC-C motif THSYN_RS06035 9da5bb2544b034a06f8f80d14ce08810 139 SUPERFAMILY SSF103642 119 138 1.21E-7 T 29-03-2018 THSYN_RS02555 b197de99c646c1b265221053f7959b5a 357 Pfam PF03724 META domain 65 175 5.5E-23 T 29-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ THSYN_RS02555 b197de99c646c1b265221053f7959b5a 357 Pfam PF03724 META domain 181 292 1.0E-26 T 29-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ THSYN_RS09925 d14076151e2c0c7b2c849d63bd69514c 65 Gene3D G3DSA:1.10.8.10 11 61 2.0E-5 T 29-03-2018 THSYN_RS09925 d14076151e2c0c7b2c849d63bd69514c 65 Pfam PF13592 Winged helix-turn helix 2 48 3.1E-10 T 29-03-2018 IPR025959 Winged helix-turn helix domain THSYN_RS02795 56242680353b54119be900b1a84541c6 481 PIRSF PIRSF004919 17 479 1.1E-142 T 29-03-2018 IPR025502 TldD THSYN_RS02795 56242680353b54119be900b1a84541c6 481 Pfam PF01523 Putative modulator of DNA gyrase 38 330 1.5E-72 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 THSYN_RS02795 56242680353b54119be900b1a84541c6 481 Gene3D G3DSA:3.30.2290.10 21 238 9.7E-56 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain THSYN_RS02795 56242680353b54119be900b1a84541c6 481 SUPERFAMILY SSF111283 22 478 5.36E-134 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 THSYN_RS26750 68e16ad9c2db6dd2cac8b3934b047666 112 Pfam PF01909 Nucleotidyltransferase domain 19 86 3.7E-10 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS26750 68e16ad9c2db6dd2cac8b3934b047666 112 SUPERFAMILY SSF81301 7 111 1.07E-19 T 29-03-2018 THSYN_RS26750 68e16ad9c2db6dd2cac8b3934b047666 112 Gene3D G3DSA:3.30.460.10 5 112 2.9E-18 T 29-03-2018 THSYN_RS03740 8b39da38d441aabff6bd0032a5ed1024 126 Pfam PF09345 Domain of unknown function (DUF1987) 7 123 8.8E-38 T 29-03-2018 IPR018530 Domain of unknown function DUF1987 THSYN_RS14405 8f44f80643bed1f6cf84eb40a68f136c 123 Pfam PF14261 Domain of unknown function (DUF4351) 62 120 2.7E-17 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS12470 d2a5acefb1a568ae8ebcc11e751d4af7 335 Pfam PF03929 PepSY-associated TM region 19 301 8.3E-29 T 29-03-2018 IPR005625 PepSY-associated TM protein THSYN_RS17850 08da80618a923676b27e812077c88463 66 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 27 59 3.0E-7 T 29-03-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THSYN_RS11095 99d6f8dc5938270eef09ed4544750c86 299 Pfam PF04280 Tim44-like domain 181 298 6.1E-11 T 29-03-2018 IPR007379 Tim44-like domain THSYN_RS11095 99d6f8dc5938270eef09ed4544750c86 299 SMART SM00978 167 298 1.1E-25 T 29-03-2018 IPR007379 Tim44-like domain THSYN_RS11095 99d6f8dc5938270eef09ed4544750c86 299 SUPERFAMILY SSF54427 180 298 2.48E-9 T 29-03-2018 IPR032710 NTF2-like domain THSYN_RS04795 c84deb8b0f4c3226ba8d51645321ea57 356 Pfam PF06250 Protein of unknown function (DUF1016) 14 329 4.0E-107 T 29-03-2018 IPR009362 Protein of unknown function DUF1016 THSYN_RS29845 be1801e532a5384e384d2565b8ac4d07 117 SUPERFAMILY SSF52343 12 114 3.27E-11 T 29-03-2018 THSYN_RS29845 be1801e532a5384e384d2565b8ac4d07 117 Gene3D G3DSA:3.40.50.80 9 114 5.9E-11 T 29-03-2018 THSYN_RS10720 2269c4e1c2664e095e0b48ed28c312cd 106 PIRSF PIRSF039032 1 105 1.5E-34 T 29-03-2018 IPR009387 Toxin HigB-2 THSYN_RS08915 a0d0ae4e146de1caf5e7480e76a76cad 162 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 29 152 1.9E-33 T 29-03-2018 IPR019223 Domain of unknown function DUF2147 THSYN_RS20905 abd1bfdc634f2419f7fbb1738c18ea89 181 Pfam PF01863 Protein of unknown function DUF45 95 151 6.1E-11 T 29-03-2018 IPR002725 Protein of unknown function DUF45 THSYN_RS23310 62c1b998f176c9adf62cbbe8572521ec 281 SUPERFAMILY SSF160104 4 279 5.62E-64 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 THSYN_RS23310 62c1b998f176c9adf62cbbe8572521ec 281 Gene3D G3DSA:2.40.400.10 3 281 2.2E-61 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 THSYN_RS23310 62c1b998f176c9adf62cbbe8572521ec 281 Pfam PF06314 Acetoacetate decarboxylase (ADC) 13 258 4.0E-30 T 29-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 THSYN_RS22665 0014f25ef44a0556da5db16eacb17a2d 526 SUPERFAMILY SSF46548 67 172 2.96E-14 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THSYN_RS22665 0014f25ef44a0556da5db16eacb17a2d 526 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 145 156 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THSYN_RS22665 0014f25ef44a0556da5db16eacb17a2d 526 Gene3D G3DSA:3.30.70.20 46 80 0.0053 T 29-03-2018 THSYN_RS22665 0014f25ef44a0556da5db16eacb17a2d 526 Gene3D G3DSA:3.30.70.20 152 185 0.018 T 29-03-2018 THSYN_RS22665 0014f25ef44a0556da5db16eacb17a2d 526 Gene3D G3DSA:3.30.70.20 81 151 4.2E-7 T 29-03-2018 THSYN_RS22665 0014f25ef44a0556da5db16eacb17a2d 526 Pfam PF13183 4Fe-4S dicluster domain 73 159 1.7E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THSYN_RS06575 8f1b99f91f1cc69468631a91f62d6377 328 Gene3D G3DSA:2.60.120.260 4 199 7.8E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS22670 e4c67326422a06a1652ccb3ec10d6163 243 Pfam PF02665 Nitrate reductase gamma subunit 74 212 1.5E-13 T 29-03-2018 IPR023234 NarG-like domain THSYN_RS22670 e4c67326422a06a1652ccb3ec10d6163 243 SUPERFAMILY SSF103501 7 232 3.4E-44 T 29-03-2018 IPR023234 NarG-like domain THSYN_RS22670 e4c67326422a06a1652ccb3ec10d6163 243 Gene3D G3DSA:1.20.950.20 5 219 6.1E-30 T 29-03-2018 THSYN_RS06080 7941cd58e8f7223fc1be48084968e37f 206 Pfam PF11006 Protein of unknown function (DUF2845) 103 201 1.8E-19 T 29-03-2018 IPR021268 Protein of unknown function DUF2845 THSYN_RS11520 9b26681471b09d7314a6d3e2263a8498 425 Pfam PF00999 Sodium/hydrogen exchanger family 9 406 6.1E-56 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 THSYN_RS30130 788a3425fcac2ebc7e23cef4d8624ae4 72 Pfam PF14454 Prokaryotic Ubiquitin 9 65 7.0E-9 T 29-03-2018 IPR032866 Prokaryotic Ubiquitin THSYN_RS31150 bfedfb08be316b908b993d4130614917 210 Pfam PF13194 Domain of unknown function (DUF4010) 71 181 3.3E-27 T 29-03-2018 IPR025105 Domain of unknown function DUF4010 THSYN_RS22450 1d4cfe47d38b24335a5a0d4dc43c9ca9 211 SUPERFAMILY SSF52980 22 177 1.66E-10 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS22450 1d4cfe47d38b24335a5a0d4dc43c9ca9 211 Gene3D G3DSA:3.90.1570.10 19 179 1.5E-21 T 29-03-2018 THSYN_RS22450 1d4cfe47d38b24335a5a0d4dc43c9ca9 211 Pfam PF05685 Putative restriction endonuclease 27 168 5.4E-18 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS05240 fa3f6fbf6451dbe75936a10011f5cc44 191 Pfam PF02342 TerD domain 1 187 2.9E-84 T 29-03-2018 IPR003325 TerD domain GO:0006950 THSYN_RS05240 fa3f6fbf6451dbe75936a10011f5cc44 191 Gene3D G3DSA:2.60.60.30 19 186 4.6E-66 T 29-03-2018 THSYN_RS25895 ae49123c2b237697f4b3bb276ccee3f0 294 Gene3D G3DSA:1.25.40.70 79 244 0.002 T 29-03-2018 THSYN_RS25070 8dc02aa48bb8379ca5e991637902cc3a 392 Pfam PF00534 Glycosyl transferases group 1 203 341 1.1E-17 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 THSYN_RS25070 8dc02aa48bb8379ca5e991637902cc3a 392 SUPERFAMILY SSF53756 9 378 1.44E-37 T 29-03-2018 THSYN_RS25070 8dc02aa48bb8379ca5e991637902cc3a 392 Gene3D G3DSA:3.40.50.2000 198 365 3.0E-27 T 29-03-2018 THSYN_RS08255 fe2c9cf9e0e3f1db75794de850532aca 410 Gene3D G3DSA:3.40.50.2000 251 395 1.6E-22 T 29-03-2018 THSYN_RS08255 fe2c9cf9e0e3f1db75794de850532aca 410 Gene3D G3DSA:3.40.50.2000 16 250 6.5E-18 T 29-03-2018 THSYN_RS08255 fe2c9cf9e0e3f1db75794de850532aca 410 SUPERFAMILY SSF53756 16 409 2.13E-52 T 29-03-2018 THSYN_RS24890 b52e6b550a8228e8dd00ef780f7f7036 97 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 17.666 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS24890 b52e6b550a8228e8dd00ef780f7f7036 97 Gene3D G3DSA:3.90.940.10 1 91 1.1E-25 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 THSYN_RS24890 b52e6b550a8228e8dd00ef780f7f7036 97 Pfam PF01192 RNA polymerase Rpb6 8 59 6.4E-17 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 THSYN_RS24890 b52e6b550a8228e8dd00ef780f7f7036 97 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 58 8.1E-21 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THSYN_RS24890 b52e6b550a8228e8dd00ef780f7f7036 97 SUPERFAMILY SSF63562 1 74 2.09E-25 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 THSYN_RS24890 b52e6b550a8228e8dd00ef780f7f7036 97 SMART SM01409 8 60 4.6E-17 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 THSYN_RS30275 6bd1a693a62ee9da787d34e9c8f6f333 148 Pfam PF10124 Mu-like prophage major head subunit gpT 28 136 1.6E-20 T 29-03-2018 IPR018774 Bacteriophage Mu, GpT THSYN_RS30445 fad17aca6b0c02480e236665bf68a7aa 108 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 93 1.5E-16 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS06205 d5d8570682712213449d6530c485d4ab 65 SUPERFAMILY SSF56349 6 57 1.45E-7 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THSYN_RS25010 8b10a7f2ffff06fd2a126a2ab75f036e 45 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 5 35 2.4E-12 T 29-03-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 THSYN_RS01835 577897d3f1ced6c8f298ba6ebd037c3a 107 Pfam PF03683 Uncharacterised protein family (UPF0175) 40 103 1.6E-15 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS22740 2845d73b53fde82a20ea9d7ab3bcbd85 256 Gene3D G3DSA:3.40.50.300 1 248 7.5E-10 T 29-03-2018 THSYN_RS22740 2845d73b53fde82a20ea9d7ab3bcbd85 256 SUPERFAMILY SSF52540 192 206 4.87E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS22740 2845d73b53fde82a20ea9d7ab3bcbd85 256 SUPERFAMILY SSF52540 2 155 4.87E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS23765 11ebeef55ce2ca7a0a82ae113f9aa671 76 Pfam PF04255 Protein of unknown function (DUF433) 10 65 2.8E-22 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS23765 11ebeef55ce2ca7a0a82ae113f9aa671 76 SUPERFAMILY SSF46689 5 70 4.3E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS23765 11ebeef55ce2ca7a0a82ae113f9aa671 76 Gene3D G3DSA:1.10.10.10 10 70 6.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS13340 20a58e1f06dae667a4e7b4ea32cfcf47 473 Pfam PF06097 Bacterial protein of unknown function (DUF945) 15 466 1.4E-49 T 29-03-2018 IPR010352 Protein of unknown function DUF945 THSYN_RS19755 7ae689e4d48165bc6ce8d2822e8e25e1 105 Pfam PF09720 Putative addiction module component 15 65 2.5E-9 T 29-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THSYN_RS04415 7fb68e07cb656ae44f8ddec427da2d32 75 Pfam PF14261 Domain of unknown function (DUF4351) 17 64 6.0E-7 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS11150 618800fc47e0993f302c3f9befd93fba 329 Gene3D G3DSA:3.40.50.2300 1 272 6.1E-5 T 29-03-2018 THSYN_RS03670 920ee4006a71c45f225be0b467fdebe3 340 Pfam PF01145 SPFH domain / Band 7 family 15 189 7.8E-16 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS03670 920ee4006a71c45f225be0b467fdebe3 340 SUPERFAMILY SSF117892 57 184 1.57E-8 T 29-03-2018 IPR001107 Band 7 domain THSYN_RS27265 eeeecb903cc9bd8186fa1eac1cdee7cd 1031 Gene3D G3DSA:2.40.50.110 709 788 7.0E-5 T 29-03-2018 THSYN_RS27265 eeeecb903cc9bd8186fa1eac1cdee7cd 1031 Pfam PF08239 Bacterial SH3 domain 729 786 1.7E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type THSYN_RS24320 020f2bc53e910659703350044ba729ab 170 Pfam PF03073 TspO/MBR family 20 159 5.9E-14 T 29-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 THSYN_RS27915 70c4fcc4c6925b505b30518c6ed318b8 434 Gene3D G3DSA:3.40.50.410 203 363 2.0E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS27915 70c4fcc4c6925b505b30518c6ed318b8 434 Pfam PF01882 Protein of unknown function DUF58 192 276 1.6E-24 T 29-03-2018 IPR002881 Domain of unknown function DUF58 THSYN_RS27915 70c4fcc4c6925b505b30518c6ed318b8 434 SUPERFAMILY SSF53300 232 361 1.28E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS29450 0f05764fb8f0de93131088b95d8ba131 198 Gene3D G3DSA:3.40.30.10 15 198 6.1E-27 T 29-03-2018 THSYN_RS29450 0f05764fb8f0de93131088b95d8ba131 198 Pfam PF00578 AhpC/TSA family 23 149 2.1E-14 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THSYN_RS29450 0f05764fb8f0de93131088b95d8ba131 198 SUPERFAMILY SSF52833 20 198 8.43E-31 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS21625 2c9f394035156cdd4a1eadc1b0ebfcf2 152 SUPERFAMILY SSF52540 22 123 2.62E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS21625 2c9f394035156cdd4a1eadc1b0ebfcf2 152 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 5 134 1.6E-43 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 THSYN_RS21625 2c9f394035156cdd4a1eadc1b0ebfcf2 152 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7 125 3.9E-36 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 THSYN_RS21625 2c9f394035156cdd4a1eadc1b0ebfcf2 152 Gene3D G3DSA:3.40.50.300 1 150 1.4E-46 T 29-03-2018 THSYN_RS04935 54285272cb19c0d5f082b4de9fa74b8a 66 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 2 58 1.7E-19 T 29-03-2018 IPR009241 Toxin HigB-like THSYN_RS14280 92593fbc73694c85a4d4d4485ab617d1 88 Pfam PF11848 Domain of unknown function (DUF3368) 45 84 7.9E-7 T 29-03-2018 IPR021799 Protein of unknown function DUF3368 THSYN_RS13920 3f6fdfcee3bd1abd632dca671fc0b286 281 Pfam PF14491 Protein of unknown function (DUF4435) 26 230 5.4E-17 T 29-03-2018 IPR029492 Domain of unknown function DUF4435 THSYN_RS19895 5d48da6d66beea5ad54c6a125da35152 213 SUPERFAMILY SSF160527 83 200 2.88E-15 T 29-03-2018 THSYN_RS19895 5d48da6d66beea5ad54c6a125da35152 213 Pfam PF01991 ATP synthase (E/31 kDa) subunit 11 200 1.6E-19 T 29-03-2018 IPR002842 ATPase, V1/A1 complex, subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THSYN_RS20920 b8f4b280db5f0f16299ec25b5ccaaf4f 328 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 39 313 5.8E-46 T 29-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system THSYN_RS02545 071bc3dc448bbd5691764cd38ab3cb41 230 Pfam PF00005 ABC transporter 15 163 2.3E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THSYN_RS02545 071bc3dc448bbd5691764cd38ab3cb41 230 SUPERFAMILY SSF52540 12 213 9.59E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THSYN_RS02545 071bc3dc448bbd5691764cd38ab3cb41 230 SMART SM00382 23 212 3.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain THSYN_RS02545 071bc3dc448bbd5691764cd38ab3cb41 230 Gene3D G3DSA:3.40.50.300 3 221 5.3E-38 T 29-03-2018 THSYN_RS23490 3c02aff661f0a1c60b1c7f482d2384a4 485 SUPERFAMILY SSF75304 2 479 4.19E-172 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THSYN_RS23490 3c02aff661f0a1c60b1c7f482d2384a4 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 9 474 93.715 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THSYN_RS23490 3c02aff661f0a1c60b1c7f482d2384a4 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 14 474 1.1E-181 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THSYN_RS23490 3c02aff661f0a1c60b1c7f482d2384a4 485 Gene3D G3DSA:3.90.1300.10 1 480 3.1E-184 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THSYN_RS23490 3c02aff661f0a1c60b1c7f482d2384a4 485 Pfam PF01425 Amidase 22 463 6.6E-164 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THSYN_RS23490 3c02aff661f0a1c60b1c7f482d2384a4 485 ProSitePatterns PS00571 Amidases signature. 149 180 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 THSYN_RS26195 237e6060a9de614b1cf04cd9ee1034d2 525 PIRSF PIRSF500217 1 525 2.7E-146 T 29-03-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 THSYN_RS26195 237e6060a9de614b1cf04cd9ee1034d2 525 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 131 356 1.1E-29 T 29-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT THSYN_RS26195 237e6060a9de614b1cf04cd9ee1034d2 525 PIRSF PIRSF016636 1 525 3.6E-146 T 29-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB THSYN_RS08435 fb699b81b0f2a0818aeb0e0c6f78cda3 65 Gene3D G3DSA:3.30.2390.10 1 65 4.4E-16 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS08435 fb699b81b0f2a0818aeb0e0c6f78cda3 65 SUPERFAMILY SSF143100 1 53 4.05E-16 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like THSYN_RS08435 fb699b81b0f2a0818aeb0e0c6f78cda3 65 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 52 8.6E-10 T 29-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system THSYN_RS11330 eceab26f85bfd7ab3ae51d44a1053124 195 Pfam PF08750 CNP1-like family 51 181 1.6E-26 T 29-03-2018 IPR014861 Uncharacterised domain CNP1 THSYN_RS33065 55f303fa71eaed240d5a28e6a915239e 111 Gene3D G3DSA:1.10.10.10 1 63 1.8E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS29745 5e39f0909a34762826a9c8ec3618f315 158 PRINTS PR00601 Bacterioferritin signature 47 67 4.8E-13 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS29745 5e39f0909a34762826a9c8ec3618f315 158 PRINTS PR00601 Bacterioferritin signature 26 46 4.8E-13 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS29745 5e39f0909a34762826a9c8ec3618f315 158 PRINTS PR00601 Bacterioferritin signature 68 88 4.8E-13 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS29745 5e39f0909a34762826a9c8ec3618f315 158 PRINTS PR00601 Bacterioferritin signature 6 25 4.8E-13 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS29745 5e39f0909a34762826a9c8ec3618f315 158 PRINTS PR00601 Bacterioferritin signature 89 109 4.8E-13 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THSYN_RS29745 5e39f0909a34762826a9c8ec3618f315 158 SUPERFAMILY SSF47240 7 143 7.55E-27 T 29-03-2018 IPR009078 Ferritin-like superfamily THSYN_RS29745 5e39f0909a34762826a9c8ec3618f315 158 Gene3D G3DSA:1.20.1260.10 1 148 8.8E-22 T 29-03-2018 IPR012347 Ferritin-related THSYN_RS29745 5e39f0909a34762826a9c8ec3618f315 158 Pfam PF00210 Ferritin-like domain 14 145 3.1E-17 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 THSYN_RS00110 8d18b765365337318281f77387a490df 263 Pfam PF01863 Protein of unknown function DUF45 34 240 1.5E-43 T 29-03-2018 IPR002725 Protein of unknown function DUF45 THSYN_RS21590 83306d2874f06904b69ff57076f1e902 71 Gene3D G3DSA:1.10.287.660 3 68 1.1E-21 T 29-03-2018 IPR029012 Helix hairpin bin domain THSYN_RS21590 83306d2874f06904b69ff57076f1e902 71 Pfam PF05082 Rop-like 5 66 1.3E-23 T 29-03-2018 IPR007774 Putative nitrogen fixation protein THSYN_RS21590 83306d2874f06904b69ff57076f1e902 71 PIRSF PIRSF037676 1 70 1.2E-18 T 29-03-2018 IPR007774 Putative nitrogen fixation protein THSYN_RS31575 cd233e53df7bb80fe1b481abb988649b 72 Pfam PF04255 Protein of unknown function (DUF433) 6 59 2.6E-16 T 29-03-2018 IPR007367 Protein of unknown function DUF433 THSYN_RS31575 cd233e53df7bb80fe1b481abb988649b 72 Gene3D G3DSA:1.10.10.10 6 63 1.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS31575 cd233e53df7bb80fe1b481abb988649b 72 SUPERFAMILY SSF46689 4 58 1.29E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 THSYN_RS10820 3108575c39ae87eafc1b125978c4d9ca 151 Pfam PF04319 NifZ domain 3 73 7.8E-31 T 29-03-2018 IPR007415 Nitrogenase MoFe maturation protein, NifZ GO:0009399 THSYN_RS06850 5559ebc3ea3b645e4efc8af7d3aec6d8 535 Pfam PF03235 Protein of unknown function DUF262 18 214 1.1E-27 T 29-03-2018 IPR004919 Domain of unknown function DUF262 THSYN_RS20760 8170c6122dc8839b4b86337f7ac2a3e2 370 Pfam PF10544 T5orf172 domain 3 84 3.9E-9 T 29-03-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding THSYN_RS21525 4a4aad3a6f742616386506e6949dc4b1 510 Pfam PF13440 Polysaccharide biosynthesis protein 47 337 4.3E-57 T 29-03-2018 THSYN_RS08040 33de513100df741f84a1bf8626feb011 155 Pfam PF01724 Domain of unknown function DUF29 5 141 1.4E-46 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS02690 af6f6c9a64b7197ecf7e4c90be00c678 440 Gene3D G3DSA:3.30.465.10 56 181 2.9E-26 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THSYN_RS02690 af6f6c9a64b7197ecf7e4c90be00c678 440 SUPERFAMILY SSF56176 37 178 3.97E-34 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THSYN_RS02690 af6f6c9a64b7197ecf7e4c90be00c678 440 Pfam PF01565 FAD binding domain 37 149 1.8E-20 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THSYN_RS24405 d549bdf78ac80c54c702053590c0a32f 71 SUPERFAMILY SSF46955 10 63 1.39E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain THSYN_RS24405 d549bdf78ac80c54c702053590c0a32f 71 Gene3D G3DSA:1.10.10.10 10 70 5.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS24875 353342712ea1cab195ae7a3f5021a265 147 Gene3D G3DSA:1.20.1380.10 39 136 3.7E-11 T 29-03-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 THSYN_RS19345 a814b3f824ff62938ab8dd7b009046c2 146 PIRSF PIRSF029598 3 135 4.0E-30 T 29-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 THSYN_RS19345 a814b3f824ff62938ab8dd7b009046c2 146 Pfam PF06146 Phosphate-starvation-inducible E 52 118 3.0E-14 T 29-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like THSYN_RS16775 0d1a00d5c423108166db26e47fa0dcc3 501 SUPERFAMILY SSF53098 116 264 1.74E-5 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS16775 0d1a00d5c423108166db26e47fa0dcc3 501 Gene3D G3DSA:1.10.10.10 2 51 0.0019 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS16775 0d1a00d5c423108166db26e47fa0dcc3 501 Pfam PF00665 Integrase core domain 117 243 4.6E-14 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 THSYN_RS16775 0d1a00d5c423108166db26e47fa0dcc3 501 Gene3D G3DSA:3.30.420.10 113 394 3.3E-17 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS08390 94c49bd491d87c290ba717c1ceb7c406 571 Gene3D G3DSA:3.30.420.10 194 350 0.0016 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS17595 94c49bd491d87c290ba717c1ceb7c406 571 Gene3D G3DSA:3.30.420.10 194 350 0.0016 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 THSYN_RS28815 3856247003c029245a06dedb042ee3c8 112 Pfam PF11848 Domain of unknown function (DUF3368) 63 108 3.7E-11 T 29-03-2018 IPR021799 Protein of unknown function DUF3368 THSYN_RS09455 9c4d3f05aa7dc561fa8195b9acdb6822 551 Pfam PF08011 PD-(D/E)XK nuclease superfamily 422 544 1.8E-18 T 29-03-2018 IPR012547 PD-(D/E)XK nuclease superfamily 9 THSYN_RS09455 9c4d3f05aa7dc561fa8195b9acdb6822 551 Pfam PF09820 Predicted AAA-ATPase 9 274 3.1E-86 T 29-03-2018 IPR018631 AAA-ATPase-like domain THSYN_RS04690 5bb5cf218565374029250e1c33dab425 140 Gene3D G3DSA:3.40.50.1010 1 140 2.3E-22 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS04690 5bb5cf218565374029250e1c33dab425 140 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 137 10.458 T 29-03-2018 IPR022907 VapC family GO:0004540 THSYN_RS04690 5bb5cf218565374029250e1c33dab425 140 Pfam PF01850 PIN domain 2 126 2.7E-11 T 29-03-2018 IPR002716 PIN domain THSYN_RS04690 5bb5cf218565374029250e1c33dab425 140 SUPERFAMILY SSF88723 1 138 2.38E-18 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS18855 63d41a5af66006382182201f3126fc27 83 Pfam PF03683 Uncharacterised protein family (UPF0175) 8 82 1.0E-19 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS24640 1600735da1bc41d038510672c0f2829f 118 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 118 20.124 T 29-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 THSYN_RS24640 1600735da1bc41d038510672c0f2829f 118 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 22 117 8.0E-40 T 29-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS23775 212e4af43fd4aee4f700e8325d98be7c 260 Pfam PF04391 Protein of unknown function (DUF533) 70 255 1.7E-46 T 29-03-2018 IPR007486 Inner membrane protein YebE THSYN_RS23775 212e4af43fd4aee4f700e8325d98be7c 260 SUPERFAMILY SSF158682 141 257 1.44E-16 T 29-03-2018 THSYN_RS23775 212e4af43fd4aee4f700e8325d98be7c 260 Gene3D G3DSA:1.10.3680.10 130 259 4.6E-16 T 29-03-2018 IPR029024 TerB-like THSYN_RS12205 9f65fd38e70e1c923bc1ce9fd1963ac9 432 SUPERFAMILY SSF56281 21 121 8.25E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS12205 9f65fd38e70e1c923bc1ce9fd1963ac9 432 SUPERFAMILY SSF56281 157 312 8.25E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS12205 9f65fd38e70e1c923bc1ce9fd1963ac9 432 Gene3D G3DSA:3.60.15.10 3 365 4.8E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS12205 9f65fd38e70e1c923bc1ce9fd1963ac9 432 Pfam PF00753 Metallo-beta-lactamase superfamily 21 62 4.1E-6 T 29-03-2018 IPR001279 Metallo-beta-lactamase THSYN_RS20875 0692875317eea4dd4b88e8b6ab6caa11 77 Pfam PF11127 Protein of unknown function (DUF2892) 9 71 4.7E-18 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 THSYN_RS17305 19e78c1a95eff669e4bf15049dd60920 993 Pfam PF09369 Domain of unknown function (DUF1998) 876 961 3.5E-6 T 29-03-2018 IPR018973 DEAD/DEAH-box helicase, putative THSYN_RS06200 1916654a86a64e468b24209e5e754731 98 SUPERFAMILY SSF55729 18 83 1.47E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase THSYN_RS06200 1916654a86a64e468b24209e5e754731 98 Gene3D G3DSA:3.40.630.30 2 87 1.0E-12 T 29-03-2018 THSYN_RS06200 1916654a86a64e468b24209e5e754731 98 Pfam PF13673 Acetyltransferase (GNAT) domain 24 82 9.1E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 THSYN_RS13185 116cb4d11270e4841899f36fbcf5fd13 86 Pfam PF03683 Uncharacterised protein family (UPF0175) 8 76 4.9E-23 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS08910 71d44d984083240d0546701f09251701 162 SUPERFAMILY SSF140931 84 137 1.23E-10 T 29-03-2018 IPR003812 Fido domain THSYN_RS08910 71d44d984083240d0546701f09251701 162 Pfam PF02661 Fic/DOC family 82 106 2.1E-6 T 29-03-2018 IPR003812 Fido domain THSYN_RS08910 71d44d984083240d0546701f09251701 162 Gene3D G3DSA:1.10.3290.10 31 85 0.018 T 29-03-2018 IPR003812 Fido domain THSYN_RS08910 71d44d984083240d0546701f09251701 162 Gene3D G3DSA:1.10.3290.10 86 158 1.1E-10 T 29-03-2018 IPR003812 Fido domain THSYN_RS23005 65ce4d9b0444fa97e6e8f86b6ddd3f51 102 Gene3D G3DSA:3.40.50.300 7 96 2.1E-5 T 29-03-2018 THSYN_RS04815 53b5c757a5ac5a578fb262c4e58d5a26 299 Gene3D G3DSA:3.90.1570.10 24 213 3.2E-18 T 29-03-2018 THSYN_RS04815 53b5c757a5ac5a578fb262c4e58d5a26 299 SUPERFAMILY SSF52980 28 212 5.36E-16 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS04815 53b5c757a5ac5a578fb262c4e58d5a26 299 Pfam PF05685 Putative restriction endonuclease 35 207 5.8E-12 T 29-03-2018 IPR008538 Domain of unknown function DUF820 THSYN_RS15975 47f79b9491f9a83bb6d85017c58a4909 282 Gene3D G3DSA:3.30.9.10 6 193 1.8E-5 T 29-03-2018 THSYN_RS26370 f2504dd3e62cfd56e6922b81a973e741 312 Gene3D G3DSA:3.40.50.1820 17 312 1.6E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS26370 f2504dd3e62cfd56e6922b81a973e741 312 Pfam PF00561 alpha/beta hydrolase fold 42 260 6.7E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS26370 f2504dd3e62cfd56e6922b81a973e741 312 SUPERFAMILY SSF53474 28 296 2.43E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS21110 01cecae052bf30d7d384bd3063d61376 319 Pfam PF14261 Domain of unknown function (DUF4351) 260 313 4.8E-8 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS21110 01cecae052bf30d7d384bd3063d61376 319 Pfam PF04754 Putative transposase, YhgA-like 4 204 6.6E-29 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS00840 04ea8ec8a5fa8c48bd64c65197c3dba7 348 Gene3D G3DSA:3.40.50.2000 163 329 4.5E-38 T 29-03-2018 THSYN_RS00840 04ea8ec8a5fa8c48bd64c65197c3dba7 348 SUPERFAMILY SSF53756 2 343 3.71E-58 T 29-03-2018 THSYN_RS00840 04ea8ec8a5fa8c48bd64c65197c3dba7 348 Pfam PF13439 Glycosyltransferase Family 4 3 156 1.2E-7 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 THSYN_RS00840 04ea8ec8a5fa8c48bd64c65197c3dba7 348 Pfam PF13692 Glycosyl transferases group 1 178 316 1.2E-28 T 29-03-2018 THSYN_RS00840 04ea8ec8a5fa8c48bd64c65197c3dba7 348 Gene3D G3DSA:3.40.50.2000 2 162 1.9E-6 T 29-03-2018 THSYN_RS03810 8be20ce046d4c347d9afa059234bb854 191 Pfam PF01169 Uncharacterized protein family UPF0016 7 80 2.0E-19 T 29-03-2018 IPR001727 Gdt1 family THSYN_RS03810 8be20ce046d4c347d9afa059234bb854 191 Pfam PF01169 Uncharacterized protein family UPF0016 104 178 3.1E-22 T 29-03-2018 IPR001727 Gdt1 family THSYN_RS28315 d1dbaffe90fc45e489a6301d43773c25 220 SUPERFAMILY SSF103501 11 215 1.07E-33 T 29-03-2018 IPR023234 NarG-like domain THSYN_RS28315 d1dbaffe90fc45e489a6301d43773c25 220 Gene3D G3DSA:1.20.950.20 9 208 5.6E-25 T 29-03-2018 THSYN_RS08720 9e28085237aa63f28098667d19300947 367 Pfam PF14907 Uncharacterised nucleotidyltransferase 24 278 8.6E-43 T 29-03-2018 THSYN_RS21760 f608adefc5ba7995a178ee52ed825ada 198 Gene3D G3DSA:3.10.620.10 11 194 7.9E-43 T 29-03-2018 IPR023128 Protein N-terminal glutamine amidohydrolase, alpha beta roll GO:0016811 THSYN_RS21760 f608adefc5ba7995a178ee52ed825ada 198 Pfam PF09764 N-terminal glutamine amidase 25 180 7.1E-36 T 29-03-2018 IPR023128 Protein N-terminal glutamine amidohydrolase, alpha beta roll GO:0016811 THSYN_RS30815 9fd1275c038daa2bd774dd0dd10c4ffa 149 Gene3D G3DSA:1.20.120.330 7 144 1.3E-7 T 29-03-2018 THSYN_RS07745 276084e1a54cd0b7df27b32ceae05938 572 Pfam PF03235 Protein of unknown function DUF262 16 242 5.8E-37 T 29-03-2018 IPR004919 Domain of unknown function DUF262 THSYN_RS07745 276084e1a54cd0b7df27b32ceae05938 572 Pfam PF07510 Protein of unknown function (DUF1524) 423 560 3.0E-27 T 29-03-2018 IPR011089 Domain of unknown function DUF1524 THSYN_RS06980 59a0f96fffa89f21bb4cc1e7c6eb452a 355 TIGRFAM TIGR01836 PHA_synth_III_C: poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit 5 354 1.5E-172 T 29-03-2018 IPR010125 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit GO:0016746|GO:0042619 THSYN_RS06980 59a0f96fffa89f21bb4cc1e7c6eb452a 355 Pfam PF00561 alpha/beta hydrolase fold 68 333 6.0E-30 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 THSYN_RS06980 59a0f96fffa89f21bb4cc1e7c6eb452a 355 Gene3D G3DSA:3.40.50.1820 28 355 6.4E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS06980 59a0f96fffa89f21bb4cc1e7c6eb452a 355 SUPERFAMILY SSF53474 53 352 9.01E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold THSYN_RS31590 a856d1a0ec2e0724fc130b4ea336b202 173 Pfam PF14487 Domain of unknown function (DUF4433) 14 168 1.7E-18 T 29-03-2018 IPR029494 Domain of unknown function DUF4433 THSYN_RS29885 fe768fbafe62669262648cc50ba42d4a 74 Pfam PF11455 Protein of unknown function (DUF3018) 8 72 1.6E-30 T 29-03-2018 IPR021558 Protein of unknown function DUF3018 THSYN_RS06155 5ecf0013e5bc6db77b8c659482ea72c8 100 SUPERFAMILY SSF143120 3 66 7.72E-8 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS06155 5ecf0013e5bc6db77b8c659482ea72c8 100 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 64 1.1E-7 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THSYN_RS06155 5ecf0013e5bc6db77b8c659482ea72c8 100 Gene3D G3DSA:3.40.1620.10 2 47 4.6E-7 T 29-03-2018 THSYN_RS25995 af49817baa027c3a3fef9d20c05f7a81 284 SUPERFAMILY SSF56300 1 226 7.16E-35 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS25995 af49817baa027c3a3fef9d20c05f7a81 284 Gene3D G3DSA:3.60.21.10 1 234 6.5E-32 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like THSYN_RS25995 af49817baa027c3a3fef9d20c05f7a81 284 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 202 5.9E-16 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 THSYN_RS25770 4a2f415aff55feb375d5096950ade025 314 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 20 302 2.5E-17 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD THSYN_RS26660 0a1b3a8a413dfbad39a294bfd6bbeb29 271 Pfam PF09955 Predicted integral membrane protein (DUF2189) 79 203 5.0E-36 T 29-03-2018 IPR018692 Predicted integral membrane protein DUF2189 THSYN_RS07420 5610f6342104aab2b37fb0a679cfce2e 483 SUPERFAMILY SSF56672 14 230 1.87E-30 T 29-03-2018 THSYN_RS07420 5610f6342104aab2b37fb0a679cfce2e 483 Gene3D G3DSA:1.10.150.20 165 236 5.3E-6 T 29-03-2018 THSYN_RS18475 3667c11a1d487c120d5ef76d0f9cfa6b 103 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 78 1.4E-7 T 29-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 THSYN_RS13595 eeec62ea2fc7d0e6fbb113950ff77953 480 Pfam PF01523 Putative modulator of DNA gyrase 20 325 1.4E-42 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 THSYN_RS13595 eeec62ea2fc7d0e6fbb113950ff77953 480 Gene3D G3DSA:3.30.2290.10 2 227 8.0E-38 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain THSYN_RS13595 eeec62ea2fc7d0e6fbb113950ff77953 480 SUPERFAMILY SSF111283 3 475 1.44E-86 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 THSYN_RS17605 bb062f5959c9e17f4195b6ca9200a41a 147 Gene3D G3DSA:1.20.120.520 2 73 6.1E-6 T 29-03-2018 THSYN_RS17605 bb062f5959c9e17f4195b6ca9200a41a 147 Pfam PF01814 Hemerythrin HHE cation binding domain 6 135 9.8E-8 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THSYN_RS00860 99151e9eaf041aeca31283a1e4e9ef47 192 Pfam PF12007 Protein of unknown function (DUF3501) 2 191 9.2E-75 T 29-03-2018 IPR021890 Protein of unknown function DUF3501 THSYN_RS03880 b94d66ef9593d62c645f1bdacc42121d 174 Pfam PF16702 Domain of unknown function (DUF5063) 13 163 7.2E-33 T 29-03-2018 IPR032025 Protein of unknown function DUF5063 THSYN_RS28640 ccd68e3137a61a1782890119a848f4b8 104 PIRSF PIRSF039032 1 104 5.5E-32 T 29-03-2018 IPR009387 Toxin HigB-2 THSYN_RS29895 7a07033bf9fe6d26c33484f750812a15 73 Pfam PF00216 Bacterial DNA-binding protein 3 52 1.4E-10 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THSYN_RS29895 7a07033bf9fe6d26c33484f750812a15 73 Gene3D G3DSA:4.10.520.10 1 62 3.0E-11 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS29895 7a07033bf9fe6d26c33484f750812a15 73 SUPERFAMILY SSF47729 3 53 3.68E-11 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THSYN_RS33215 6cf7db823a16918b182f5390728d15a3 230 Gene3D G3DSA:3.20.20.70 57 227 1.5E-8 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS33215 6cf7db823a16918b182f5390728d15a3 230 Pfam PF04476 4-HFC-P synthase 4 218 2.1E-64 T 29-03-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|KEGG: 00902+4.2.3.15|MetaCyc: PWY-3041|MetaCyc: PWY-5254|MetaCyc: PWY-5423|MetaCyc: PWY-7410 THSYN_RS33215 6cf7db823a16918b182f5390728d15a3 230 SUPERFAMILY SSF51366 7 204 3.44E-5 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THSYN_RS33215 6cf7db823a16918b182f5390728d15a3 230 Gene3D G3DSA:3.20.20.70 2 56 0.033 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THSYN_RS33215 6cf7db823a16918b182f5390728d15a3 230 PIRSF PIRSF015957 2 228 1.8E-46 T 29-03-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|KEGG: 00902+4.2.3.15|MetaCyc: PWY-3041|MetaCyc: PWY-5254|MetaCyc: PWY-5423|MetaCyc: PWY-7410 THSYN_RS25550 6702cf09147ba2e58119dc52f75b61f8 81 Pfam PF04226 Transglycosylase associated protein 32 79 4.5E-12 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 THSYN_RS12805 ec0c942e324eb9393ad82265c6d1e22d 149 Pfam PF06146 Phosphate-starvation-inducible E 49 114 6.8E-11 T 29-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like THSYN_RS13410 63df3622960d7d93a9ea66e685a06f24 181 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 84 95 - T 29-03-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 THSYN_RS13410 63df3622960d7d93a9ea66e685a06f24 181 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 61 175 3.1E-30 T 29-03-2018 IPR011969 Clan AA aspartic peptidase, C-terminal THSYN_RS13410 63df3622960d7d93a9ea66e685a06f24 181 Gene3D G3DSA:2.40.70.10 58 166 1.6E-17 T 29-03-2018 IPR021109 Aspartic peptidase domain THSYN_RS13410 63df3622960d7d93a9ea66e685a06f24 181 Pfam PF13975 gag-polyprotein putative aspartyl protease 75 162 1.9E-23 T 29-03-2018 THSYN_RS13410 63df3622960d7d93a9ea66e685a06f24 181 SUPERFAMILY SSF50630 63 165 3.75E-18 T 29-03-2018 IPR021109 Aspartic peptidase domain THSYN_RS21455 42db965f34790b93cc5447c73a898a4e 161 Pfam PF05069 Phage virion morphogenesis family 11 156 2.6E-19 T 29-03-2018 IPR006522 Phage virion morphogensis protein THSYN_RS05230 091f1f8964d76357342db8228fba5a71 346 Pfam PF04332 Protein of unknown function (DUF475) 48 339 1.2E-117 T 29-03-2018 IPR007427 Protein of unknown function DUF475 THSYN_RS09880 0b905c2723dc4d65a2a0cdfdc7c389e9 290 Pfam PF08378 Nuclease-related domain 24 67 1.0E-4 T 29-03-2018 IPR011528 Nuclease-related domain, NERD THSYN_RS10425 46ed3bed628d832bb90a0b607f9442f7 162 PIRSF PIRSF016481 1 162 8.4E-46 T 29-03-2018 IPR007446 Pilus assembly protein PilP THSYN_RS10425 46ed3bed628d832bb90a0b607f9442f7 162 Pfam PF04351 Pilus assembly protein, PilP 15 160 9.6E-50 T 29-03-2018 IPR007446 Pilus assembly protein PilP THSYN_RS12900 6aeeb5c5a749a963efaa3abaa1e79c57 327 Pfam PF05661 Protein of unknown function (DUF808) 4 301 8.0E-111 T 29-03-2018 IPR008526 Inner membrane protein YedI THSYN_RS12900 6aeeb5c5a749a963efaa3abaa1e79c57 327 PIRSF PIRSF016660 1 313 2.2E-115 T 29-03-2018 IPR008526 Inner membrane protein YedI THSYN_RS11225 c3c3c4f2a068d3acde6ade93ed2e0bae 132 Pfam PF07030 Protein of unknown function (DUF1320) 12 110 2.3E-7 T 29-03-2018 IPR009752 Bacteriophage Mu, Gp36 THSYN_RS20305 1b8538104ac4942878b2dc044125b068 91 Pfam PF04319 NifZ domain 11 84 2.8E-14 T 29-03-2018 IPR007415 Nitrogenase MoFe maturation protein, NifZ GO:0009399 THSYN_RS19910 6a7b834a997fdd9b355bb66580357ed2 482 Pfam PF06114 IrrE N-terminal-like domain 366 449 2.8E-10 T 29-03-2018 IPR010359 IrrE N-terminal-like domain THSYN_RS10415 11c811fd1b9aaa218bccc9cee6287d4e 190 Pfam PF05137 Fimbrial assembly protein (PilN) 100 175 2.6E-22 T 29-03-2018 IPR007813 Fimbrial assembly PilN THSYN_RS14845 e04f0f086c03aba92446463e38f491b9 154 Pfam PF11103 Protein of unknown function (DUF2887) 4 65 1.9E-10 T 29-03-2018 IPR022573 Protein of unknown function DUF2887 THSYN_RS14845 e04f0f086c03aba92446463e38f491b9 154 Gene3D G3DSA:1.10.10.60 82 117 1.7E-4 T 29-03-2018 THSYN_RS26345 d9bacdc74a5a73ef9b27836df5c7dec9 198 SUPERFAMILY SSF56235 1 188 3.32E-52 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THSYN_RS26345 d9bacdc74a5a73ef9b27836df5c7dec9 198 Gene3D G3DSA:3.60.60.10 1 197 3.5E-53 T 29-03-2018 THSYN_RS26345 d9bacdc74a5a73ef9b27836df5c7dec9 198 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 1 171 2.8E-36 T 29-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal THSYN_RS02885 dfb33f93d4083775f5900a9b9e6dd405 114 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 24 109 1.6E-22 T 29-03-2018 IPR009241 Toxin HigB-like THSYN_RS12625 5ff232c2ac8164160769e48645e14196 186 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 15 150 8.4E-39 T 29-03-2018 IPR018639 Domain of unknown function DUF2062 THSYN_RS18245 3f644bbc4a7dd295b75e86206ed658c8 361 Pfam PF01594 AI-2E family transporter 14 327 1.9E-53 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like THSYN_RS16370 fa70a1dd786677de721dadf5cfb0f6c9 217 Pfam PF14261 Domain of unknown function (DUF4351) 156 214 2.3E-18 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS30555 08718a51015588fb0f207234e2f1b272 245 Pfam PF01066 CDP-alcohol phosphatidyltransferase 68 134 4.6E-10 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THSYN_RS30555 08718a51015588fb0f207234e2f1b272 245 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 112 134 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THSYN_RS28965 15af01a98488921504a713fb0777f09e 179 Pfam PF01724 Domain of unknown function DUF29 7 144 8.6E-45 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS26530 eccc88e89c89958e7d65ba0b90e12561 276 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 241 264 5.2E-4 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS26415 ba801c31a07712727544b22abcb3e4e4 104 SUPERFAMILY SSF52833 4 103 9.73E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold THSYN_RS26415 ba801c31a07712727544b22abcb3e4e4 104 Gene3D G3DSA:3.40.30.10 3 104 3.2E-28 T 29-03-2018 THSYN_RS08655 ed3fcc5e425f081e6ae8dc798b177c6d 246 Gene3D G3DSA:3.40.50.880 6 216 4.1E-7 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like THSYN_RS19735 03cf8db03946b7db6d1495f684462bfc 440 Gene3D G3DSA:1.20.120.330 130 392 7.7E-7 T 29-03-2018 THSYN_RS07070 d4f3390a645127f9750b6702a966e21e 106 Gene3D G3DSA:3.30.460.10 3 106 2.4E-17 T 29-03-2018 THSYN_RS07070 d4f3390a645127f9750b6702a966e21e 106 Pfam PF01909 Nucleotidyltransferase domain 19 51 9.8E-10 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS07070 d4f3390a645127f9750b6702a966e21e 106 SUPERFAMILY SSF81301 9 104 1.08E-16 T 29-03-2018 THSYN_RS21170 20201e280b039019c62e62b3b8ff41e9 66 Pfam PF10049 Protein of unknown function (DUF2283) 2 50 2.9E-17 T 29-03-2018 IPR019270 Protein of unknown function DUF2283 THSYN_RS29105 fe1569d0578dc04ad1080dc97482b2c6 782 Pfam PF07793 Protein of unknown function (DUF1631) 25 770 8.2E-169 T 29-03-2018 IPR012434 Protein of unknown function DUF1631 THSYN_RS26045 2340b27d2dad5df4af6c15ee7805a71c 100 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 38 95 7.0E-18 T 29-03-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system THSYN_RS18105 f8488d56ce5486acfe42281f3da85c7a 94 Pfam PF03683 Uncharacterised protein family (UPF0175) 10 80 2.4E-24 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS00810 f64aaa69c329ce58b4796e79d2017b56 153 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 145 4.7E-48 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 THSYN_RS00810 f64aaa69c329ce58b4796e79d2017b56 153 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 32.232 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 THSYN_RS09555 b1d1f343bde54bd179557cdb9bd4ff35 174 Gene3D G3DSA:3.40.50.1240 1 167 2.5E-29 T 29-03-2018 IPR029033 Histidine phosphatase superfamily THSYN_RS09555 b1d1f343bde54bd179557cdb9bd4ff35 174 SUPERFAMILY SSF53254 1 149 6.55E-28 T 29-03-2018 IPR029033 Histidine phosphatase superfamily THSYN_RS09555 b1d1f343bde54bd179557cdb9bd4ff35 174 SMART SM00855 4 117 2.6E-6 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THSYN_RS09555 b1d1f343bde54bd179557cdb9bd4ff35 174 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 73 8.7E-13 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THSYN_RS29480 c49f4b5225013b6458e74aae5144d349 209 Pfam PF02310 B12 binding domain 86 182 7.6E-12 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 THSYN_RS29480 c49f4b5225013b6458e74aae5144d349 209 Gene3D G3DSA:3.40.50.280 63 203 9.9E-25 T 29-03-2018 THSYN_RS29480 c49f4b5225013b6458e74aae5144d349 209 SUPERFAMILY SSF52242 69 200 3.4E-25 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 THSYN_RS06905 0641ecfdc1f0ffd39e0a1e98517c4fef 139 SUPERFAMILY SSF55718 1 133 1.85E-19 T 29-03-2018 IPR003033 SCP2 sterol-binding domain THSYN_RS06905 0641ecfdc1f0ffd39e0a1e98517c4fef 139 Gene3D G3DSA:3.30.1050.10 3 130 5.1E-16 T 29-03-2018 IPR003033 SCP2 sterol-binding domain THSYN_RS27355 a307d1be1d93083aa26a303a1005f4c5 400 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 301 390 2.4E-22 T 29-03-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain THSYN_RS27355 a307d1be1d93083aa26a303a1005f4c5 400 Pfam PF04326 Putative DNA-binding domain 14 125 1.0E-13 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 THSYN_RS06700 1f15c733768290b1f923ad7a1578de17 151 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 15 140 2.5E-20 T 29-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THSYN_RS29995 f51f95017721ddb434ace45728f3794d 272 Pfam PF04116 Fatty acid hydroxylase superfamily 83 219 1.8E-29 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 THSYN_RS16955 5ed85ff8b48627210776bdaf7ed5c5c4 57 SUPERFAMILY SSF54786 1 56 1.77E-11 T 29-03-2018 THSYN_RS16955 5ed85ff8b48627210776bdaf7ed5c5c4 57 Gene3D G3DSA:3.30.920.30 1 57 2.9E-14 T 29-03-2018 THSYN_RS16955 5ed85ff8b48627210776bdaf7ed5c5c4 57 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 4 55 1.8E-10 T 29-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 THSYN_RS07180 69f0f298ca793f654bcfa47117489e5a 217 Pfam PF11103 Protein of unknown function (DUF2887) 3 191 5.3E-22 T 29-03-2018 IPR022573 Protein of unknown function DUF2887 THSYN_RS15810 40a81c2f6ca9f940cb338ae437ed0459 273 Pfam PF02517 CAAX protease self-immunity 125 224 2.1E-18 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 THSYN_RS20455 5500cbbe19a914cb7e974f108656d9af 99 Gene3D G3DSA:3.30.460.10 6 86 1.9E-5 T 29-03-2018 THSYN_RS20455 5500cbbe19a914cb7e974f108656d9af 99 SUPERFAMILY SSF81301 10 82 3.54E-6 T 29-03-2018 THSYN_RS12025 e55a16b195429def3ff0b395fd5d24e3 75 Pfam PF10047 Protein of unknown function (DUF2281) 7 74 3.8E-19 T 29-03-2018 IPR018739 Domain of unknown function DUF2281 THSYN_RS12115 feee10ecd351ee2cbbf517477017dd35 145 Pfam PF01724 Domain of unknown function DUF29 6 143 4.6E-44 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS17955 18dd4d9023e0ff27c85a9fec766f1b8a 156 Pfam PF04314 Copper chaperone PCu(A)C 31 139 2.8E-41 T 29-03-2018 IPR007410 Copper chaperone PCuAC THSYN_RS17955 18dd4d9023e0ff27c85a9fec766f1b8a 156 SUPERFAMILY SSF110087 10 146 1.29E-47 T 29-03-2018 IPR007410 Copper chaperone PCuAC THSYN_RS04260 8e71745d12ecbca92de8ccc701709fe7 303 Pfam PF01925 Sulfite exporter TauE/SafE 61 295 6.8E-27 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 THSYN_RS21945 8965d0b28fe62994264ac389481b6e91 97 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 7 85 1.6E-22 T 29-03-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THSYN_RS27760 3236af95f20d8e2ad63abbeab326c821 342 Pfam PF04754 Putative transposase, YhgA-like 37 238 1.8E-46 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS09185 f4f623decdac42c37810fe59adbc50f2 184 Pfam PF04143 Sulphur transport 34 172 3.1E-16 T 29-03-2018 IPR007272 Sulphur transport domain THSYN_RS13285 d6df09b8d7f701b213f8703aeaacce71 222 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 19 216 7.8E-45 T 29-03-2018 IPR006214 Bax inhibitor 1-related THSYN_RS29820 def6a80b882b5681ad0a7b272669a193 101 Pfam PF03746 LamB/YcsF family 3 86 9.6E-22 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF THSYN_RS29820 def6a80b882b5681ad0a7b272669a193 101 SUPERFAMILY SSF88713 3 89 1.93E-22 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THSYN_RS29820 def6a80b882b5681ad0a7b272669a193 101 Gene3D G3DSA:3.20.20.370 1 93 1.4E-23 T 29-03-2018 THSYN_RS31965 56031fd6dead654ed8626c4353e58a06 75 Pfam PF09905 DNA-binding protein VF530 7 68 2.1E-33 T 29-03-2018 IPR018668 DNA-binding protein VF530-like GO:0003677 THSYN_RS31965 56031fd6dead654ed8626c4353e58a06 75 Gene3D G3DSA:1.10.720.30 14 70 1.3E-29 T 29-03-2018 IPR003034 SAP domain THSYN_RS09890 8a3436f35f22eabf81d19a1cd54b1f50 66 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 2 57 2.5E-11 T 29-03-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THSYN_RS12500 9bf78e194a67cd2a0f93c41b2086778b 131 Pfam PF06868 Protein of unknown function (DUF1257) 21 125 1.9E-19 T 29-03-2018 IPR009666 Uncharacterised protein family Ycf35 THSYN_RS07195 f8fd37af6ff56530e93588b7ce08c509 303 Pfam PF14261 Domain of unknown function (DUF4351) 242 300 3.5E-17 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS07195 f8fd37af6ff56530e93588b7ce08c509 303 Gene3D G3DSA:1.10.10.60 218 261 4.4E-4 T 29-03-2018 THSYN_RS07195 f8fd37af6ff56530e93588b7ce08c509 303 Pfam PF11103 Protein of unknown function (DUF2887) 3 205 1.3E-26 T 29-03-2018 IPR022573 Protein of unknown function DUF2887 THSYN_RS32140 4c7d888c025496911e7077793e5cd642 238 Pfam PF07077 Protein of unknown function (DUF1345) 43 216 3.9E-57 T 29-03-2018 IPR009781 Protein of unknown function DUF1345 THSYN_RS16355 797edc3a3731a0281bf01fa690f50e47 52 Pfam PF14261 Domain of unknown function (DUF4351) 1 49 2.1E-17 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS12965 205bbcd90dfe6fecd14dd45199451064 111 Gene3D G3DSA:3.30.460.10 4 111 3.4E-15 T 29-03-2018 THSYN_RS12965 205bbcd90dfe6fecd14dd45199451064 111 Pfam PF01909 Nucleotidyltransferase domain 12 55 3.0E-9 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THSYN_RS12965 205bbcd90dfe6fecd14dd45199451064 111 SUPERFAMILY SSF81301 9 111 3.52E-15 T 29-03-2018 THSYN_RS09210 83fb4fb5ef5eef9d8113025ae15bf04f 72 Pfam PF07788 PD-(D/E)XK nuclease superfamily 6 58 2.1E-12 T 29-03-2018 IPR012431 PD-(D/E)XK nuclease THSYN_RS31865 dcc2d122e44da6d2cd541236c88f62e7 158 SUPERFAMILY SSF54637 12 145 4.37E-23 T 29-03-2018 IPR029069 HotDog domain THSYN_RS31865 dcc2d122e44da6d2cd541236c88f62e7 158 Pfam PF01575 MaoC like domain 18 112 1.1E-9 T 29-03-2018 IPR002539 MaoC-like domain THSYN_RS31865 dcc2d122e44da6d2cd541236c88f62e7 158 Gene3D G3DSA:3.10.129.10 6 148 1.1E-24 T 29-03-2018 THSYN_RS31885 a5f56c9f888be193f2c3f3a723431cdf 118 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 2 67 5.4E-8 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS25915 ca203c8cd4671be8c332dd3cd5293155 360 Pfam PF13511 Domain of unknown function (DUF4124) 220 272 1.0E-10 T 29-03-2018 IPR025392 Domain of unknown function DUF4124 THSYN_RS18650 8156c80e0e616687ec99eb63e170ab4e 360 Pfam PF03050 Transposase IS66 family 6 301 4.4E-44 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS19825 69e0277a8fcd2922a5317d908ba7105c 278 Gene3D G3DSA:2.60.120.260 30 228 7.4E-6 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS17240 20b464123e145ab01b3691874f368138 97 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 14 91 1.8E-22 T 29-03-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THSYN_RS11180 4c3e89103fe2ad9bb5af8df07a1bcf2e 543 Pfam PF06074 Protein of unknown function (DUF935) 13 537 1.6E-153 T 29-03-2018 IPR009279 Protein of unknown function DUF935 THSYN_RS13580 dd07bc92a6b5aa422dcd2ab2a57674d1 445 Pfam PF10091 Putative glucoamylase 192 418 2.3E-72 T 29-03-2018 IPR019282 Domain of unknown function DUF2329 THSYN_RS13580 dd07bc92a6b5aa422dcd2ab2a57674d1 445 PIRSF PIRSF028431 3 444 9.6E-151 T 29-03-2018 IPR016883 Uncharacterised conserved protein UCP028431 THSYN_RS30380 263cc3db432ba2ef0697bc1b4ead7180 95 Gene3D G3DSA:1.20.5.780 2 85 2.4E-13 T 29-03-2018 THSYN_RS15890 fc13d8a316e02d2637ec04bacfaf2dda 468 Pfam PF03600 Citrate transporter 51 416 5.4E-44 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 THSYN_RS10935 b3c83c368f8bec34cb0795d35c6e288e 128 Pfam PF01850 PIN domain 4 116 1.6E-8 T 29-03-2018 IPR002716 PIN domain THSYN_RS10935 b3c83c368f8bec34cb0795d35c6e288e 128 SUPERFAMILY SSF88723 3 116 1.43E-15 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS10935 b3c83c368f8bec34cb0795d35c6e288e 128 Gene3D G3DSA:3.40.50.1010 1 124 5.0E-16 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS20355 061ca0572ca6abfe9d5bc9592bb65530 95 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 21 90 1.6E-28 T 29-03-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 THSYN_RS04620 e6c97fc7c0ff985a49104cdd41f790a6 260 Pfam PF10030 Uncharacterized protein conserved in bacteria (DUF2272) 119 248 6.6E-25 T 29-03-2018 IPR019262 Domain of unknown function DUF2272 THSYN_RS17110 031347712ed8416adb429a014e239bd4 168 Pfam PF13635 Domain of unknown function (DUF4143) 14 108 7.5E-20 T 29-03-2018 IPR025420 Domain of unknown function DUF4143 THSYN_RS31515 16472272a0920e969cb140f19d402a3a 777 Pfam PF06934 Fatty acid cis/trans isomerase (CTI) 95 774 1.4E-142 T 29-03-2018 IPR010706 Fatty acid cis-trans isomerase THSYN_RS08005 2b5846137bc14488520bb1fab22a822c 150 Pfam PF08269 Cache domain 48 149 1.2E-20 T 29-03-2018 IPR004010 Double Cache domain 2 THSYN_RS08005 2b5846137bc14488520bb1fab22a822c 150 Gene3D G3DSA:3.30.450.20 17 150 1.1E-28 T 29-03-2018 THSYN_RS08005 2b5846137bc14488520bb1fab22a822c 150 SMART SM01049 21 102 4.1E-10 T 29-03-2018 IPR033480 Single Cache domain 2 THSYN_RS09960 980d3cfb0cc7478a043a2c9cee3a3acc 814 Gene3D G3DSA:1.20.140.50 58 701 0.15 T 29-03-2018 THSYN_RS30920 ca033be4f0ccda3b288732258e5bf2f4 740 SMART SM00028 529 562 0.0084 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THSYN_RS30920 ca033be4f0ccda3b288732258e5bf2f4 740 SUPERFAMILY SSF48452 474 562 3.76E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS30920 ca033be4f0ccda3b288732258e5bf2f4 740 Gene3D G3DSA:1.25.40.120 301 595 1.3E-5 T 29-03-2018 THSYN_RS15770 4578e92a2dbe27c4842c3a07d8132101 97 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 8 68 5.5E-8 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS16395 7e769121cb070127567529c5bfaca242 127 Pfam PF04134 Protein of unknown function, DUF393 10 117 1.2E-23 T 29-03-2018 IPR007263 Protein of unknown function DUF393 THSYN_RS00390 e3bb92b3a961683efa6c5115fd597e9e 147 SUPERFAMILY SSF53850 27 134 8.14E-11 T 29-03-2018 THSYN_RS00390 e3bb92b3a961683efa6c5115fd597e9e 147 Gene3D G3DSA:3.40.190.10 28 147 9.4E-11 T 29-03-2018 THSYN_RS22970 1a81fba45b2cc0b3ae5b4c4f9e5d1a7b 87 Gene3D G3DSA:1.10.1220.10 1 40 3.1E-9 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS22970 1a81fba45b2cc0b3ae5b4c4f9e5d1a7b 87 SUPERFAMILY SSF47598 3 49 8.89E-10 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 THSYN_RS04650 88b665e21241e4379c9a7d65d1ec13a7 234 Gene3D G3DSA:3.30.1380.10 85 230 3.5E-19 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS04650 88b665e21241e4379c9a7d65d1ec13a7 234 SUPERFAMILY SSF55166 84 231 1.02E-26 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THSYN_RS04650 88b665e21241e4379c9a7d65d1ec13a7 234 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 156 231 3.1E-22 T 29-03-2018 THSYN_RS21695 87eef38eba38300d984901e6d0a1990f 76 Gene3D G3DSA:3.40.50.1010 1 74 1.7E-8 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS21695 87eef38eba38300d984901e6d0a1990f 76 SUPERFAMILY SSF88723 2 69 1.82E-7 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS23345 2f96402a2633a7437615723bc2e00787 299 Pfam PF11103 Protein of unknown function (DUF2887) 3 199 1.9E-28 T 29-03-2018 IPR022573 Protein of unknown function DUF2887 THSYN_RS31975 e4245629d902a0c9f2c58dec64756ccb 66 Pfam PF04754 Putative transposase, YhgA-like 1 66 1.3E-7 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS16160 81c03e66b47e5fad7537408bc4f5c373 113 Pfam PF07238 PilZ domain 12 100 3.8E-9 T 29-03-2018 IPR009875 PilZ domain GO:0035438 THSYN_RS16160 81c03e66b47e5fad7537408bc4f5c373 113 Gene3D G3DSA:2.40.10.220 26 103 3.3E-7 T 29-03-2018 THSYN_RS26510 a62b226da9c3943517001becc84c15ab 355 Pfam PF14907 Uncharacterised nucleotidyltransferase 39 269 1.4E-35 T 29-03-2018 THSYN_RS19935 4f2c3d0f8494f756373ff4917cc977eb 788 Pfam PF03235 Protein of unknown function DUF262 22 103 5.1E-15 T 29-03-2018 IPR004919 Domain of unknown function DUF262 THSYN_RS31160 22430df7e5a2ef4de014286a88d40d7f 121 SUPERFAMILY SSF103481 49 119 6.8E-5 T 29-03-2018 THSYN_RS27755 378bbe8042636b90b041490eaf093f86 315 Pfam PF04754 Putative transposase, YhgA-like 6 207 1.6E-46 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS27755 378bbe8042636b90b041490eaf093f86 315 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 7 274 1.2E-15 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA THSYN_RS12180 783e53966e415135dc13cc4fa7f379c6 433 Gene3D G3DSA:3.90.20.10 252 411 3.0E-4 T 29-03-2018 THSYN_RS32720 007fd98f7b83e444d419555d8a4740c3 259 SUPERFAMILY SSF48371 17 199 1.53E-13 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 THSYN_RS32720 007fd98f7b83e444d419555d8a4740c3 259 Gene3D G3DSA:1.25.10.10 5 246 1.9E-12 T 29-03-2018 IPR011989 Armadillo-like helical THSYN_RS30770 e8b26216838c1aafd38092e222c94de8 282 Pfam PF04446 tRNAHis guanylyltransferase 1 121 6.1E-27 T 29-03-2018 IPR024956 tRNAHis guanylyltransferase catalytic domain GO:0000287|GO:0006400|GO:0008193 Reactome: R-HSA-6782315 THSYN_RS30770 e8b26216838c1aafd38092e222c94de8 282 Pfam PF14413 Thg1 C terminal domain 125 212 5.9E-11 T 29-03-2018 IPR025845 Thg1 C-terminal domain Reactome: R-HSA-6782315 THSYN_RS24930 3fe2592e740822666a84852355266ff7 189 Pfam PF02325 YGGT family 16 82 4.6E-21 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 THSYN_RS24930 3fe2592e740822666a84852355266ff7 189 Pfam PF02325 YGGT family 108 177 2.6E-18 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 THSYN_RS28490 f23e5e5cb15b387022f202855848d0eb 178 Pfam PF11154 Protein of unknown function (DUF2934) 131 166 4.9E-13 T 29-03-2018 IPR021327 Protein of unknown function DUF2934 THSYN_RS22065 d99d739a418df97beaa506823c4e7c10 135 Pfam PF08011 PD-(D/E)XK nuclease superfamily 33 124 2.2E-24 T 29-03-2018 IPR012547 PD-(D/E)XK nuclease superfamily 9 THSYN_RS32795 fe25806395ac0a79e173d6cb536cf1b2 91 Gene3D G3DSA:3.40.1620.10 7 88 8.2E-8 T 29-03-2018 THSYN_RS14710 b9b5eb9c21058c31bb4bb9bf2aa88237 508 Pfam PF00361 Proton-conducting membrane transporter 126 411 6.7E-38 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS14710 b9b5eb9c21058c31bb4bb9bf2aa88237 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 161 185 2.2E-11 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS14710 b9b5eb9c21058c31bb4bb9bf2aa88237 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 234 258 2.2E-11 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS14710 b9b5eb9c21058c31bb4bb9bf2aa88237 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 379 405 2.2E-11 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS14710 b9b5eb9c21058c31bb4bb9bf2aa88237 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 131 150 2.2E-11 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THSYN_RS16220 ab1d8186774668c53f2be65395e278e7 182 Pfam PF02620 Uncharacterized ACR, COG1399 62 179 3.3E-18 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD THSYN_RS14805 c21e66e62a5ff673a1153d1c0d8c44fa 466 Pfam PF07394 Protein of unknown function (DUF1501) 50 442 5.6E-38 T 29-03-2018 IPR010869 Protein of unknown function DUF1501 THSYN_RS11440 49c42bafe296644e425d619aff9743a0 603 Pfam PF03235 Protein of unknown function DUF262 21 255 2.3E-23 T 29-03-2018 IPR004919 Domain of unknown function DUF262 THSYN_RS08510 fb27423535a6e2c67234d0ad8853f5f5 246 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 163 6.0E-16 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase THSYN_RS21305 ac8e69b47a4fa34f7d840a5f2a19b817 459 TIGRFAM TIGR03097 PEP_O_lig_1: probable O-glycosylation ligase, exosortase A-associated 2 403 1.0E-143 T 29-03-2018 IPR017528 Conserved hypothetical protein CHP03097, O-antigen ligase-related THSYN_RS21305 ac8e69b47a4fa34f7d840a5f2a19b817 459 Pfam PF04932 O-Antigen ligase 201 338 3.4E-17 T 29-03-2018 IPR007016 O-antigen ligase-related THSYN_RS13490 5e6d40810f969a2ed308409a57f67dbb 273 Pfam PF07589 PEP-CTERM motif 245 266 5.6E-5 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS13490 5e6d40810f969a2ed308409a57f67dbb 273 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 246 266 0.0026 T 29-03-2018 IPR013424 PEP-CTERM protein-sorting domain THSYN_RS13375 4604f289cd479fcd3e494452e205f537 84 Pfam PF12441 CopG antitoxin of type II toxin-antitoxin system 5 80 1.5E-10 T 29-03-2018 IPR022148 CopG antitoxin THSYN_RS10790 859d979cd786fbbfca26456ea96f4161 155 Gene3D G3DSA:1.10.357.10 3 150 4.9E-4 T 29-03-2018 THSYN_RS12050 5702aa6b7e637fc00e44c520983d1b74 422 Pfam PF13657 HipA N-terminal domain 27 127 1.9E-8 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 THSYN_RS12050 5702aa6b7e637fc00e44c520983d1b74 422 Pfam PF07804 HipA-like C-terminal domain 172 386 2.5E-46 T 29-03-2018 IPR012893 HipA-like, C-terminal THSYN_RS08705 2be0feb8a434c72dbe48cb452d2c6c57 73 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 50 6.8E-14 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain THSYN_RS23210 7a0a3201d058243e49fda505b496ba90 91 Pfam PF03683 Uncharacterised protein family (UPF0175) 8 80 4.5E-23 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS23210 7a0a3201d058243e49fda505b496ba90 91 Gene3D G3DSA:1.10.1220.10 44 64 7.1E-4 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THSYN_RS02215 f11ff3e01f7c00ee7c91acbe91fe4dd1 139 Gene3D G3DSA:2.60.120.380 22 139 8.4E-14 T 29-03-2018 THSYN_RS22350 94e77524b3506cb85ab0fc47596b50fe 114 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 19 103 2.2E-7 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS15860 572c53fc4d1b1a10afaf691483cc67b4 338 Pfam PF01548 Transposase 6 145 2.3E-14 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THSYN_RS15860 572c53fc4d1b1a10afaf691483cc67b4 338 Pfam PF02371 Transposase IS116/IS110/IS902 family 213 298 3.0E-14 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THSYN_RS21220 345844826fc4e40755882e2d56b8473e 113 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 99 2.7E-7 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 THSYN_RS21220 345844826fc4e40755882e2d56b8473e 113 Gene3D G3DSA:3.30.160.100 1 103 1.5E-10 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 THSYN_RS21220 345844826fc4e40755882e2d56b8473e 113 SUPERFAMILY SSF69754 1 101 3.27E-8 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 THSYN_RS06945 7dd84e61cc0ac81e939be619e94a1457 401 ProSitePatterns PS01219 Ammonium transporters signature. 156 181 - T 29-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 THSYN_RS06945 7dd84e61cc0ac81e939be619e94a1457 401 Gene3D G3DSA:1.10.3430.10 1 374 5.1E-91 T 29-03-2018 THSYN_RS06945 7dd84e61cc0ac81e939be619e94a1457 401 Pfam PF00909 Ammonium Transporter Family 12 391 1.1E-90 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 THSYN_RS06945 7dd84e61cc0ac81e939be619e94a1457 401 SUPERFAMILY SSF111352 7 374 3.01E-94 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 THSYN_RS19730 d8611fe2fea2771eb4866666878e3187 74 Gene3D G3DSA:1.20.5.320 2 74 3.6E-5 T 29-03-2018 THSYN_RS26515 778c953ca58fef7915a9cdede75990f3 103 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 26 92 2.0E-14 T 29-03-2018 IPR008792 Coenzyme PQQ synthesis D THSYN_RS00615 64323f79d385179eaa54d997e0cb512b 66 Gene3D G3DSA:3.40.50.1010 2 65 2.5E-4 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS00615 64323f79d385179eaa54d997e0cb512b 66 SUPERFAMILY SSF88723 8 59 1.37E-6 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS26460 a692eb79c9d41335335345040d211d45 145 Pfam PF01724 Domain of unknown function DUF29 3 140 2.8E-48 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS13295 4750f54347d887febd07cdeb41a8d138 248 Gene3D G3DSA:3.10.100.10 54 207 3.3E-4 T 29-03-2018 IPR016186 C-type lectin-like/link domain THSYN_RS03335 44a95aab4ef3cc976dc33956628c537d 618 Pfam PF13584 Oxygen tolerance 23 524 3.5E-99 T 29-03-2018 IPR025738 Aerotolerance-related protein BatD THSYN_RS18460 160e8d01a4370d6c6f5c51724ea27322 115 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 102 4.4E-18 T 29-03-2018 THSYN_RS22545 a19e447d2ae5cb2a6581f5941b01e532 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 55 72 8.3E-61 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22545 a19e447d2ae5cb2a6581f5941b01e532 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 29 50 8.3E-61 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22545 a19e447d2ae5cb2a6581f5941b01e532 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 78 101 8.3E-61 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22545 a19e447d2ae5cb2a6581f5941b01e532 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 134 157 8.3E-61 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22545 a19e447d2ae5cb2a6581f5941b01e532 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 103 121 8.3E-61 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22545 a19e447d2ae5cb2a6581f5941b01e532 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 196 219 8.3E-61 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22545 a19e447d2ae5cb2a6581f5941b01e532 223 Pfam PF03379 CcmB protein 5 220 9.6E-74 T 29-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THSYN_RS22545 a19e447d2ae5cb2a6581f5941b01e532 223 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 8 219 3.8E-72 T 29-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria THSYN_RS22545 a19e447d2ae5cb2a6581f5941b01e532 223 PIRSF PIRSF002764 1 223 2.1E-76 T 29-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria THSYN_RS27095 ecdc2c43e12a89a3ebeeedb0f771352d 77 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 6 51 4.5E-6 T 29-03-2018 IPR022453 Zinc finger, MqsA-type THSYN_RS08820 c9f9f2ce087feed239ed7694d7eba0de 182 SUPERFAMILY SSF160443 90 172 4.18E-17 T 29-03-2018 IPR002625 Smr domain THSYN_RS08820 c9f9f2ce087feed239ed7694d7eba0de 182 Pfam PF01713 Smr domain 91 172 3.0E-25 T 29-03-2018 IPR002625 Smr domain THSYN_RS08820 c9f9f2ce087feed239ed7694d7eba0de 182 SMART SM00463 88 172 1.2E-12 T 29-03-2018 IPR002625 Smr domain THSYN_RS11210 577a335a9d53313ee34f0310bfab6765 322 Pfam PF10124 Mu-like prophage major head subunit gpT 42 160 4.1E-32 T 29-03-2018 IPR018774 Bacteriophage Mu, GpT THSYN_RS13020 4e60c7043aad844244c1e77724ea6758 140 Pfam PF02472 Biopolymer transport protein ExbD/TolR 14 136 8.3E-28 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 THSYN_RS29975 eb3f3356287d8e526598fc57d186a486 238 Gene3D G3DSA:1.20.120.330 88 230 2.9E-5 T 29-03-2018 THSYN_RS29975 eb3f3356287d8e526598fc57d186a486 238 Gene3D G3DSA:1.20.5.340 1 87 0.021 T 29-03-2018 THSYN_RS31765 51f3328ad247f0cc5773f35b7459cd44 212 Pfam PF13835 Domain of unknown function (DUF4194) 19 185 6.9E-46 T 29-03-2018 IPR025449 Protein of unknown function DUF4194 THSYN_RS14115 dbe81300476b9cfe9bd7b1be77eb0d01 96 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 31 89 3.2E-19 T 29-03-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system THSYN_RS14380 eac3485c04ac3f928382844d82aeac9e 350 Pfam PF03773 Predicted permease 53 347 3.5E-71 T 29-03-2018 IPR005524 Predicted permease DUF318 THSYN_RS10160 8f3a01f91068f34a644ff93222cd2a0c 96 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 23 90 4.1E-24 T 29-03-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 THSYN_RS19090 0939939ca71cf4abc067414da382b383 310 Pfam PF02535 ZIP Zinc transporter 166 305 4.3E-21 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 THSYN_RS14150 2d2a5381a5eb6a05deed06d5948b8cac 52 Pfam PF11752 Protein of unknown function (DUF3309) 4 52 5.3E-22 T 29-03-2018 IPR021738 Protein of unknown function DUF3309 THSYN_RS19285 824fab8e8584dd408ce31043e103d2e8 96 Pfam PF17253 Family of unknown function (DUF5320) 1 92 1.7E-8 T 29-03-2018 IPR035205 Protein of unknown function DUF5320 THSYN_RS09635 5a79b119ffdd6b14475792c62fd37126 327 Gene3D G3DSA:2.160.10.20 108 217 1.3E-4 T 29-03-2018 THSYN_RS25490 8ff655d5b74926e686eea5827fcd0ee4 255 Pfam PF07103 Protein of unknown function (DUF1365) 9 248 1.4E-62 T 29-03-2018 IPR010775 Protein of unknown function DUF1365 THSYN_RS15970 fd8283361c462976536f1db2442a6fcd 1391 Gene3D G3DSA:3.40.50.300 11 250 0.0015 T 29-03-2018 THSYN_RS18765 65e52fe94279d79a57e236eedca7c9a5 105 Gene3D G3DSA:2.40.10.220 11 105 2.3E-8 T 29-03-2018 THSYN_RS04060 c4f456325c369387e4f6512fd2dd3be9 107 Gene3D G3DSA:1.25.40.10 3 106 1.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THSYN_RS27690 5a879ca7490e7dc1cb9ad0142b79d2b7 115 Pfam PF11006 Protein of unknown function (DUF2845) 42 111 7.2E-8 T 29-03-2018 IPR021268 Protein of unknown function DUF2845 THSYN_RS18095 ac0ed440c7e0b5588cbc796d0038e6c7 87 Pfam PF03683 Uncharacterised protein family (UPF0175) 10 82 3.9E-20 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS04770 4c091f279c7388866c32c8526644632b 238 Pfam PF01863 Protein of unknown function DUF45 24 228 8.7E-57 T 29-03-2018 IPR002725 Protein of unknown function DUF45 THSYN_RS05505 87d11f31a1eb8280e0d10abebf62b5a4 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.6E-28 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 THSYN_RS05505 87d11f31a1eb8280e0d10abebf62b5a4 106 SUPERFAMILY SSF103481 5 104 5.1E-19 T 29-03-2018 THSYN_RS04225 a426b8a3609a23661d287f17da401612 66 Gene3D G3DSA:1.20.5.780 2 54 9.6E-4 T 29-03-2018 THSYN_RS27470 aa5f5318e2b394eb16cc91d526b7570a 295 SUPERFAMILY SSF46565 159 200 4.97E-7 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS27470 aa5f5318e2b394eb16cc91d526b7570a 295 Gene3D G3DSA:1.10.287.110 71 201 9.2E-7 T 29-03-2018 IPR001623 DnaJ domain THSYN_RS26600 94f94c994326460e086f9bd6e4671642 104 Pfam PF14242 Domain of unknown function (DUF4342) 8 87 1.8E-27 T 29-03-2018 IPR025642 Domain of unknown function DUF4342 THSYN_RS00290 db12f250b77d3fbb6f80e212f1952595 296 SUPERFAMILY SSF161098 11 296 3.92E-66 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS00290 db12f250b77d3fbb6f80e212f1952595 296 Gene3D G3DSA:1.10.3720.10 1 283 5.8E-40 T 29-03-2018 THSYN_RS00290 db12f250b77d3fbb6f80e212f1952595 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 286 1.6E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THSYN_RS26275 db4a527936992b301188b8ae87bc6b71 224 Pfam PF03843 Outer membrane lipoprotein Slp family 28 179 1.4E-46 T 29-03-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 THSYN_RS11885 0d645e1f6591ab59bf9f23293482b245 141 Pfam PF05121 Gas vesicle protein K 57 140 7.5E-32 T 29-03-2018 IPR007805 Gas vesicle protein GvpK GO:0031412 THSYN_RS24510 1d2c306e06fdc14401aab3418836a9bd 49 Pfam PF11295 Protein of unknown function (DUF3096) 12 47 1.2E-15 T 29-03-2018 IPR021446 Protein of unknown function DUF3096 THSYN_RS04960 75cd67b58fda16dd29b1810882a98b8c 558 Gene3D G3DSA:1.10.10.10 2 129 8.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain THSYN_RS32760 d2eaa744ba965fa0e80bea4a5629cc6d 159 Gene3D G3DSA:1.20.120.330 33 157 5.3E-7 T 29-03-2018 THSYN_RS04330 e67311b2510c95025b85f58b9de378aa 194 TIGRFAM TIGR04174 IPTL_CTERM: IPTL-CTERM protein sorting domain 161 184 3.6E-8 T 29-03-2018 IPR026442 IPTL-CTERM protein sorting domain THSYN_RS18415 9a37a295ad409f38898674f3046a6228 393 Pfam PF06250 Protein of unknown function (DUF1016) 20 375 6.2E-107 T 29-03-2018 IPR009362 Protein of unknown function DUF1016 THSYN_RS09815 ef3daa191cdde2ba195486cd19b262dc 98 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 36 72 1.7E-7 T 29-03-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system THSYN_RS09855 9be9bd445917c55f7a273c66a9ad5de0 218 Pfam PF14487 Domain of unknown function (DUF4433) 13 213 3.9E-49 T 29-03-2018 IPR029494 Domain of unknown function DUF4433 THSYN_RS30780 120d505fc28e368c47ab2e746281a462 148 Pfam PF03055 Retinal pigment epithelial membrane protein 5 140 4.0E-16 T 29-03-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 THSYN_RS18445 0e9e907830f017cc6afb34d6afa44eca 88 Pfam PF14076 Domain of unknown function (DUF4258) 17 84 4.7E-7 T 29-03-2018 IPR025354 Protein of unknown function DUF4258 THSYN_RS18380 0c1e99e8e71623839bf9cbce8a9d9f59 342 Pfam PF03595 Voltage-dependent anion channel 33 329 1.7E-55 T 29-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 THSYN_RS26620 703473ea36cf56205f8f08e4b919201e 137 Gene3D G3DSA:1.20.1170.10 25 129 5.4E-6 T 29-03-2018 THSYN_RS01030 0ccc828724db0c894d3a0a9aa77b8722 137 Pfam PF09945 Predicted membrane protein (DUF2177) 6 128 3.1E-45 T 29-03-2018 IPR018687 Protein of unknown function DUF2177, membrane THSYN_RS32960 b3fda9d869de2e3943c7fe22f3ffb8c1 143 Pfam PF07704 Rv0623-like transcription factor 53 133 8.6E-13 T 29-03-2018 IPR011660 Antitoxin VapB-like THSYN_RS20575 a05f50ca1d403a8a69870a24febac275 92 Gene3D G3DSA:3.40.50.410 20 75 4.3E-4 T 29-03-2018 IPR002035 von Willebrand factor, type A THSYN_RS12245 0cbea7d7cdc6a8efafeb4399d9e3e9b5 70 Pfam PF14261 Domain of unknown function (DUF4351) 14 62 7.0E-6 T 29-03-2018 IPR025587 Domain of unknown function DUF4351 THSYN_RS29245 74c84b17e3c0ae2efbb82e9afdf5bdac 983 TIGRFAM TIGR04174 IPTL_CTERM: IPTL-CTERM protein sorting domain 954 980 5.3E-5 T 29-03-2018 IPR026442 IPTL-CTERM protein sorting domain THSYN_RS06860 fcf508f25bc84ff51abc9afb9de66ced 270 Pfam PF02405 Permease MlaE 58 265 3.3E-41 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 THSYN_RS22620 db66aeb9b5f4b42924dbf0e30620408b 421 Gene3D G3DSA:3.30.230.10 59 195 0.0012 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THSYN_RS20950 e7d118d5ad9c5ff87a5835ab0df375c7 380 Pfam PF06250 Protein of unknown function (DUF1016) 16 362 1.1E-97 T 29-03-2018 IPR009362 Protein of unknown function DUF1016 THSYN_RS00250 a4bc839bdf4504d680f9c198034b8eef 396 Gene3D G3DSA:3.40.50.300 4 281 3.2E-6 T 29-03-2018 THSYN_RS17600 f1f5e35c98c776926564e28d6be3475c 139 Pfam PF02371 Transposase IS116/IS110/IS902 family 12 86 5.9E-13 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THSYN_RS27480 9f7cfa7d4fe785d08689475441944796 346 Gene3D G3DSA:2.60.40.1180 1 69 2.5E-6 T 29-03-2018 THSYN_RS29625 f0ec651f70029083555ba0bc3373417f 465 Pfam PF07812 TfuA-like protein 60 182 5.4E-34 T 29-03-2018 IPR012924 TfuA-like, core THSYN_RS18275 3418dd4be20084367b92eaf2904e6927 206 Pfam PF14103 Domain of unknown function (DUF4276) 74 198 3.1E-8 T 29-03-2018 IPR025455 Protein of unknown function DUF4276 THSYN_RS29865 5993b70cd6289bca11cd20987dbf0449 64 Pfam PF11839 Alanine-zipper, major outer membrane lipoprotein 28 64 2.3E-6 T 29-03-2018 IPR021793 Major outer membrane lipoprotein Oprl THSYN_RS18240 2b6b687cb0ad6faeb0c74fea16b6cf1b 88 Pfam PF13670 Peptidase propeptide and YPEB domain 11 80 3.8E-7 T 29-03-2018 IPR025711 PepSY domain THSYN_RS32695 4b84ee63709687699491aa179173e44d 127 Pfam PF05488 PAAR motif 13 107 1.3E-14 T 29-03-2018 IPR008727 PAAR motif THSYN_RS07425 210b327768cb04440c14e3796d1a6a4e 274 Pfam PF02582 Uncharacterised ACR, YagE family COG1723 55 222 2.0E-24 T 29-03-2018 IPR003734 Domain of unknown function DUF155 THSYN_RS25265 4716a3f2c97eb0d4adf246fd3250a0e7 275 Pfam PF01061 ABC-2 type transporter 27 234 3.9E-24 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 THSYN_RS06800 d18ddfe94d5db9aaf762d43d4e4f5a69 465 Pfam PF14907 Uncharacterised nucleotidyltransferase 132 365 1.7E-34 T 29-03-2018 THSYN_RS29530 ab4b3c0d3c4def4d7659ae18fd7e8abb 73 Pfam PF03389 MobA/MobL family 2 57 2.0E-7 T 29-03-2018 IPR005053 MobA/MobL protein THSYN_RS27090 c7b9316514bb2c67db61c55e3a4a14d2 105 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 39 93 1.3E-17 T 29-03-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system THSYN_RS32955 1cf5ed320339cf98f9264f4ab3fd9225 84 Pfam PF03683 Uncharacterised protein family (UPF0175) 8 81 3.4E-27 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS31065 6b5d6ade6024e4809d9e36ca89465af6 119 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 24 114 4.3E-23 T 29-03-2018 IPR009241 Toxin HigB-like THSYN_RS31750 78350c939ffd6ff620bbc966001ecf6a 94 Gene3D G3DSA:3.30.390.30 1 53 9.6E-4 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THSYN_RS01355 cf000f8fd90a77a0da32db2c8b530e89 339 Pfam PF07786 Protein of unknown function (DUF1624) 3 164 2.8E-7 T 29-03-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-6798695 THSYN_RS04730 0fafaa5093833c1bc0131f1550e64628 245 Pfam PF14355 Abortive infection C-terminus 160 236 3.7E-19 T 29-03-2018 IPR026001 Abortive infection protein-like, C-terminal domain THSYN_RS32075 e75bed7258dc5efdce3c5405a24c6b1c 159 SUPERFAMILY SSF88723 1 129 1.6E-7 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS32075 e75bed7258dc5efdce3c5405a24c6b1c 159 Gene3D G3DSA:3.40.50.1010 1 138 2.4E-13 T 29-03-2018 IPR029060 PIN domain-like THSYN_RS25525 ff2da8dd6d1bad093da99ee2087ba885 229 Gene3D G3DSA:2.60.120.260 24 206 1.8E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like THSYN_RS30430 3a0632086c85edf0f59b6d67702d785c 195 Pfam PF05309 TraE protein 1 175 2.9E-30 T 29-03-2018 IPR007973 Pilus assembly TraE GO:0000746 THSYN_RS02370 509bcfc94cf6a2bb25e97375484263b9 111 Gene3D G3DSA:1.20.120.330 33 110 5.9E-6 T 29-03-2018 THSYN_RS19880 c0af253c3ae7f42a0fce2b6ebfcac598 126 TIGRFAM TIGR03698 clan_AA_DTGF: clan AA aspartic protease, AF_0612 family 5 111 1.1E-22 T 29-03-2018 IPR022274 Peptidase aspartic, AF0612 THSYN_RS19880 c0af253c3ae7f42a0fce2b6ebfcac598 126 Gene3D G3DSA:2.40.70.10 4 113 3.2E-8 T 29-03-2018 IPR021109 Aspartic peptidase domain THSYN_RS18550 c01c9197a77b09ab2b953fad6aebcb09 93 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 1 42 2.2E-13 T 29-03-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB THSYN_RS10310 b318c699d225ba20bce52f6702aa0d32 304 Pfam PF10881 Protein of unknown function (DUF2726) 53 175 1.9E-21 T 29-03-2018 IPR024402 Domain of unknown function DUF2726 THSYN_RS15425 80427f4ebdfa683b085fe8d94f58a5bb 198 Pfam PF14065 Protein of unknown function (DUF4255) 13 185 2.7E-31 T 29-03-2018 IPR025351 Protein of unknown function DUF4255 THSYN_RS06960 395fa583894650b134cf638486ea3142 163 Pfam PF13511 Domain of unknown function (DUF4124) 32 105 9.7E-6 T 29-03-2018 IPR025392 Domain of unknown function DUF4124 THSYN_RS06020 a746ceb0f80ae3c4a83fc24f5a184128 151 Pfam PF17228 Sulphur globule protein 42 150 4.0E-13 T 29-03-2018 IPR035173 Sulphur globule protein THSYN_RS03390 084233b9c3ef2cbdddc90165c67ec4ea 310 Pfam PF02705 K+ potassium transporter 15 305 8.0E-123 T 29-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 THSYN_RS05140 c4d6336e5c36027d4595b43ae14727b1 421 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 309 403 5.6E-20 T 29-03-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain THSYN_RS05140 c4d6336e5c36027d4595b43ae14727b1 421 Pfam PF04326 Putative DNA-binding domain 14 140 4.5E-10 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 THSYN_RS24505 51e498b97b503d1a65f5dcda78080841 84 SUPERFAMILY SSF103473 1 82 9.81E-6 T 29-03-2018 IPR020846 Major facilitator superfamily domain THSYN_RS24505 51e498b97b503d1a65f5dcda78080841 84 Pfam PF05977 Transmembrane secretion effector 1 81 4.3E-14 T 29-03-2018 IPR010290 Transmembrane secretion effector THSYN_RS24505 51e498b97b503d1a65f5dcda78080841 84 Gene3D G3DSA:1.20.1250.20 1 84 3.1E-4 T 29-03-2018 THSYN_RS29265 85384c2ae1743670e062727f0c6294fb 336 Pfam PF01882 Protein of unknown function DUF58 210 285 1.6E-12 T 29-03-2018 IPR002881 Domain of unknown function DUF58 THSYN_RS29585 d55e3245f913fd2b9028554642356a16 89 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 5 81 1.6E-16 T 29-03-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THSYN_RS08135 20e5366aa5d4e7f17d787ae3f32d7450 323 TIGRFAM TIGR04106 cas8c_GSU0052: CRISPR-associated protein GSU0052/csb3, Dpsyc system 16 307 1.1E-41 T 29-03-2018 IPR026391 CRISPR-associated protein GSU0052/csb3, Dpsyc system THSYN_RS04740 7f9119fc0c882e8e2160f07a11ad497e 167 Gene3D G3DSA:1.10.150.130 63 165 8.6E-6 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal THSYN_RS23015 c800461bcf35c7c175bda36ddb8f4f49 145 Pfam PF01724 Domain of unknown function DUF29 7 142 1.2E-47 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS20015 3c0902efbd4bdd5c6389fa20ed630c4f 379 Pfam PF01594 AI-2E family transporter 12 338 2.6E-45 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like THSYN_RS00800 5fcf8bc44012f19a807e6961b94aaa24 76 Pfam PF03683 Uncharacterised protein family (UPF0175) 18 75 6.8E-17 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS20310 d2ec607ea48bb7d6871cf3267719d7db 184 Pfam PF00892 EamA-like transporter family 39 179 5.4E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 THSYN_RS20310 d2ec607ea48bb7d6871cf3267719d7db 184 SUPERFAMILY SSF103481 104 182 1.09E-11 T 29-03-2018 THSYN_RS29125 6915d2a08ef40bfce795f9a943ccaa32 397 Pfam PF05940 NnrS protein 14 391 1.9E-103 T 29-03-2018 IPR010266 NnrS THSYN_RS01550 7b1ec27c6bc4465ab929447d317ee9d4 267 Gene3D G3DSA:3.40.1800.10 39 133 4.3E-6 T 29-03-2018 THSYN_RS02615 455c454ac743edb9ab4b0540598eaa68 1083 Pfam PF04465 Protein of unknown function (DUF499) 154 482 4.7E-22 T 29-03-2018 IPR007555 Protein of unknown function DUF499 THSYN_RS12255 4e036984bca0b8cff2d89581735fc678 90 Pfam PF14076 Domain of unknown function (DUF4258) 16 81 3.0E-7 T 29-03-2018 IPR025354 Protein of unknown function DUF4258 THSYN_RS02400 a921d2bbc7cccc2f097fa41b0f71a035 83 Pfam PF03683 Uncharacterised protein family (UPF0175) 10 81 3.8E-18 T 29-03-2018 IPR005368 Uncharacterised protein family UPF0175 THSYN_RS30880 7a30f571ca715e2d18bf7919acdc06f8 72 Pfam PF05114 Protein of unknown function (DUF692) 15 62 3.8E-9 T 29-03-2018 IPR007801 Uncharacterised protein family UPF0276 THSYN_RS21225 b7320bdb2c3309bcf5ff22598fcbe9aa 373 Pfam PF16537 Type II secretion system protein B 314 371 1.6E-14 T 29-03-2018 IPR032389 Type II secretion system protein B THSYN_RS19145 7ed6909abffa736e0e3e855626a8160e 208 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 193 8.6E-31 T 29-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 THSYN_RS08665 b859b5dd019d5f0ae8ebeef7967ac4d2 143 Pfam PF01724 Domain of unknown function DUF29 32 121 3.3E-18 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS04900 c483d89e0c4fa7d8ad73b49c2030b262 160 Gene3D G3DSA:1.20.120.580 9 157 3.1E-14 T 29-03-2018 IPR008201 Protein of unknown function DUF86 THSYN_RS18865 f09819c3497470c47a08e850e2af2b96 704 Gene3D G3DSA:3.40.50.450 16 238 1.5E-16 T 29-03-2018 THSYN_RS17460 4b63afc55231bde5ee4650ea5ed219fb 356 Pfam PF01594 AI-2E family transporter 20 344 1.4E-64 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like THSYN_RS22270 3d01f8a3a1437652e4e4b31b36c0342d 165 Pfam PF07617 Protein of unknown function (DUF1579) 20 124 1.9E-5 T 29-03-2018 IPR011473 Protein of unknown function DUF1579 THSYN_RS29365 1647c797eef622a4d124cb4b485e97ab 169 Pfam PF03692 Putative zinc- or iron-chelating domain 30 113 3.5E-8 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein THSYN_RS32030 83f49c1e0cfa4986834ab3d57ca3d80d 317 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 19 284 2.1E-63 T 29-03-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 THSYN_RS27940 61dcdff530a60c5a19dff8963ebe91cf 239 Pfam PF06271 RDD family 22 143 1.0E-16 T 29-03-2018 IPR010432 RDD THSYN_RS26455 2e1ec033f927e4bfbba624d1308beecd 150 Pfam PF01724 Domain of unknown function DUF29 7 143 3.8E-48 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS27225 9677d72af00c7ac705437de6fa115b3e 161 Pfam PF08909 Domain of unknown function (DUF1854) 33 159 1.4E-42 T 29-03-2018 IPR015005 Domain of unknown function DUF1854 THSYN_RS16910 6c67fa2949d5a27244966b71243edd98 147 Pfam PF11026 Protein of unknown function (DUF2721) 18 141 1.8E-33 T 29-03-2018 IPR021279 Protein of unknown function DUF2721 THSYN_RS27315 2a6a03053b8dbde0cd44b25bd491020f 181 Pfam PF09832 Uncharacterized protein conserved in bacteria (DUF2059) 100 153 1.4E-17 T 29-03-2018 IPR018637 Domain of unknown function DUF2059 THSYN_RS25645 e0c2dc76993a9a8e15b7ebc650ac289f 179 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 4 179 5.4E-61 T 29-03-2018 IPR018636 Protein of unknown function DUF2058 THSYN_RS23500 7014b3cebfe95dc8ef3f6a03ee911eca 224 Pfam PF14103 Domain of unknown function (DUF4276) 27 191 1.9E-7 T 29-03-2018 IPR025455 Protein of unknown function DUF4276 THSYN_RS27905 289c0a09551874c5754ba25ca48d95a4 139 Pfam PF03682 Uncharacterised protein family (UPF0158) 20 138 7.7E-7 T 29-03-2018 IPR005361 Uncharacterised protein family UPF0158 THSYN_RS03450 ccdaca3d547694b8a7bc91d2c1dacbbb 1111 Pfam PF04465 Protein of unknown function (DUF499) 299 709 2.0E-25 T 29-03-2018 IPR007555 Protein of unknown function DUF499 THSYN_RS33175 8946f65b2aabe8be9bed6b5666313b76 76 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 5 66 2.3E-25 T 29-03-2018 IPR021074 Formate dehydrogenase, delta subunit THSYN_RS01015 ec9f148756cb3507e2a34e637df3de0c 194 Pfam PF04754 Putative transposase, YhgA-like 1 131 5.9E-27 T 29-03-2018 IPR006842 Transposase (putative), YhgA-like THSYN_RS25805 9d7ccacf017d18e0c7fe49e1fe63a41f 165 Pfam PF03703 Bacterial PH domain 81 153 1.1E-11 T 29-03-2018 IPR005182 Domain of unknown function DUF304 THSYN_RS07555 85813cdeda463410727f7756638dc70d 196 Gene3D G3DSA:2.40.240.20 111 149 0.17 T 29-03-2018 THSYN_RS03070 38bab472c783b7fdd25847f72ca9db49 234 Pfam PF13546 DDE superfamily endonuclease 51 214 2.1E-37 T 29-03-2018 THSYN_RS14980 8d9dd11a1284f3ac13a7914f4f4ea684 140 Pfam PF03703 Bacterial PH domain 56 128 6.0E-11 T 29-03-2018 IPR005182 Domain of unknown function DUF304 THSYN_RS18860 864677aa64cf26fee6063728e6cc74ab 166 Pfam PF11848 Domain of unknown function (DUF3368) 114 158 7.1E-11 T 29-03-2018 IPR021799 Protein of unknown function DUF3368 THSYN_RS16005 2d794701b328e6974179a449244df226 263 Pfam PF03235 Protein of unknown function DUF262 61 122 1.8E-16 T 29-03-2018 IPR004919 Domain of unknown function DUF262 THSYN_RS31805 d00d3dceb45faa86b1991edf0c7c691e 311 TIGRFAM TIGR01476 chlor_syn_BchG: bacteriochlorophyll/chlorophyll synthetase 27 307 3.8E-97 T 29-03-2018 IPR006372 Bacteriochlorophyll/chlorophyll synthetase THSYN_RS31805 d00d3dceb45faa86b1991edf0c7c691e 311 Pfam PF01040 UbiA prenyltransferase family 43 277 7.8E-35 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 THSYN_RS12895 e1a17874c47fd19e28ec33f00b625663 203 SUPERFAMILY SSF52980 29 189 3.0E-6 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THSYN_RS29810 df1548059e2cb11070d306161bd75f2b 163 Pfam PF04536 TPM domain 25 140 3.5E-13 T 29-03-2018 IPR007621 TPM domain THSYN_RS01055 cecedbbbdd56e5ede32294628388ccea 420 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 117 193 3.2E-9 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THSYN_RS01240 cfafacdbd6f7186da498ea0f7ba47ccb 504 Pfam PF13440 Polysaccharide biosynthesis protein 40 332 2.4E-52 T 29-03-2018 THSYN_RS30070 1c9509c489feaa264162dbcb432a1181 336 Pfam PF13280 WYL domain 152 330 7.6E-24 T 29-03-2018 IPR026881 WYL domain THSYN_RS25420 0c4a6a1ff90a9d4591dc8812bac87525 113 Pfam PF07788 PD-(D/E)XK nuclease superfamily 76 102 1.8E-5 T 29-03-2018 IPR012431 PD-(D/E)XK nuclease THSYN_RS12485 130aba51c7143fe7a7f112ca08932bae 111 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 15 100 6.9E-11 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THSYN_RS27990 66baabd159c80988c62c726beda45731 412 Pfam PF16074 Type IV Pilus-assembly protein W 275 403 1.9E-6 T 29-03-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 THSYN_RS20335 489ab7969291a4ce9b22e31812f5fbe8 220 Pfam PF03547 Membrane transport protein 67 203 7.5E-11 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 THSYN_RS11335 993a47591c3b605fba1f14fc1f486ae0 311 Pfam PF04228 Putative neutral zinc metallopeptidase 1 306 2.9E-123 T 29-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative THSYN_RS13140 7ef197831bdddd46b06b665ca339b487 152 Pfam PF01724 Domain of unknown function DUF29 6 142 1.6E-46 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS04095 c43765d9f06fb5dada5576725d89ab51 237 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 20 174 1.0E-20 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component THSYN_RS06075 77e75a84fbe7f4687b054e67f206ad2a 441 Pfam PF04932 O-Antigen ligase 196 362 4.7E-12 T 29-03-2018 IPR007016 O-antigen ligase-related THSYN_RS17355 81104a379ac9d90f92a30ffe30ecae31 64 Pfam PF10047 Protein of unknown function (DUF2281) 8 34 4.6E-7 T 29-03-2018 IPR018739 Domain of unknown function DUF2281 THSYN_RS14755 2d909b9540a67630f83ac03c9de062e0 470 Pfam PF01098 Cell cycle protein 118 427 1.5E-57 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 THSYN_RS16000 99e475239b3a18c5f260aadc7eaac525 70 Pfam PF09722 Protein of unknown function (DUF2384) 17 67 4.5E-12 T 29-03-2018 IPR024467 Domain of unknown function DUF2384 THSYN_RS10445 343d9ed5213f45a097d15cae804af0c1 194 Pfam PF07298 NnrU protein 3 188 4.7E-45 T 29-03-2018 IPR009915 NnrU domain THSYN_RS06150 027fa2b997e2bdca1e9cb14e40015dd6 294 Gene3D G3DSA:1.20.5.990 97 220 5.6E-5 T 29-03-2018 THSYN_RS30800 b0e38bf4d95af1e6d9e85a43eedf5834 1239 Gene3D G3DSA:3.40.50.300 44 444 0.022 T 29-03-2018 THSYN_RS14925 85f67bc6000a26c237b0e998f7c96fe0 84 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 25 73 1.7E-7 T 29-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 THSYN_RS13640 66431da0dd1d95b1083dcbc432face0d 386 Pfam PF16074 Type IV Pilus-assembly protein W 260 383 2.3E-25 T 29-03-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 THSYN_RS20350 91a716e10635255fec088fd78653f9b9 132 Gene3D G3DSA:1.10.260.40 50 132 1.9E-5 T 29-03-2018 THSYN_RS07200 327c4f098eecf04b300668ad97b88afa 283 Pfam PF01061 ABC-2 type transporter 37 234 7.6E-12 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 THSYN_RS16535 0acae9ab53fe5009424879f43dbabe09 300 Pfam PF02754 Cysteine-rich domain 6 90 6.4E-9 T 29-03-2018 IPR004017 Cysteine-rich domain THSYN_RS16535 0acae9ab53fe5009424879f43dbabe09 300 Pfam PF02754 Cysteine-rich domain 157 244 5.4E-10 T 29-03-2018 IPR004017 Cysteine-rich domain THSYN_RS24810 c207c0e8c2ad088b85793e7659946510 146 Pfam PF02472 Biopolymer transport protein ExbD/TolR 7 138 2.0E-20 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 THSYN_RS05300 76926066a3f77646c81b2c12aa981c86 109 Pfam PF07007 Lysozyme inhibitor LprI 28 106 2.8E-7 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal THSYN_RS25285 f602b615c0c5b32ef23d4433cd2c6d7c 81 Gene3D G3DSA:1.20.120.330 1 47 2.5E-4 T 29-03-2018 THSYN_RS21440 29d1cb63f6da78faaf3cce8372b5c538 529 Pfam PF03050 Transposase IS66 family 220 485 3.6E-44 T 29-03-2018 IPR004291 Transposase, IS66 THSYN_RS02955 b7e5dc65d9b4d1dae1becdc1ee7510a3 160 Gene3D G3DSA:3.30.1450.10 75 148 6.9E-5 T 29-03-2018 THSYN_RS11450 627d4ec53324c92dd6bbb6d3765022bb 393 Gene3D G3DSA:3.40.50.300 1 234 2.0E-6 T 29-03-2018 THSYN_RS04465 cb41431cde9a4f1d0f83a20aef8fd0df 78 Pfam PF10047 Protein of unknown function (DUF2281) 7 64 7.2E-7 T 29-03-2018 IPR018739 Domain of unknown function DUF2281 THSYN_RS06900 276d2be5022c355f06ce95fa39a33c12 213 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 69 4.5E-7 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THSYN_RS24175 93b21e21c1cdf4664bb8d05ce3d6886f 156 Pfam PF01724 Domain of unknown function DUF29 7 152 1.5E-41 T 29-03-2018 IPR002636 Protein from unkown function DUF29 THSYN_RS13370 2f65a689f161ee830777108a6309cec2 94 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 12 84 1.4E-6 T 29-03-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THSYN_RS19155 7893c8b5cead079bbefa819ea91e3026 225 Pfam PF08856 Protein of unknown function (DUF1826) 24 224 6.9E-56 T 29-03-2018 IPR014955 Protein of unknown function DUF1826 THSYN_RS26925 2774043207701db492c35aa2845b3bd4 111 Pfam PF09997 Predicted membrane protein (DUF2238) 29 83 9.4E-19 T 29-03-2018 IPR014509 Uncharacterised conserved protein UCP020606 THSYN_RS06240 d0f136f1c470fc7ea77eebc5185aebcb 260 Gene3D G3DSA:1.20.5.50 64 168 1.5E-8 T 29-03-2018 THSYN_RS00185 88481a56284a7ec2784dd11c3978af2d 172 Gene3D G3DSA:2.60.120.430 40 152 6.8E-21 T 29-03-2018 THSYN_RS05325 1cfbce0e4de70968292552cf95e2fd40 157 Gene3D G3DSA:1.10.101.10 16 103 5.3E-4 T 29-03-2018 IPR002477 Peptidoglycan binding-like THSYN_RS00925 4b8fd0d32a3112b7c48a4a0462202e03 519 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 55 213 1.5E-23 T 29-03-2018 THSYN_RS16280 1224be39321fb67e94d2cf9373a45dd3 383 Pfam PF14907 Uncharacterised nucleotidyltransferase 61 321 2.8E-30 T 29-03-2018