locus-tag	class	description
AM608_RS00010	COG1131	(ABC) transporter
AM608_RS00025	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AM608_RS00030	COG1428	Deoxynucleoside kinase
AM608_RS00035	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AM608_RS00045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM608_RS00085	COG2304	oxidoreductase activity
AM608_RS00090	COG0254	rRNA binding
AM608_RS00105	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM608_RS00115	COG0442	prolyl-tRNA aminoacylation
AM608_RS00120	COG0793	Belongs to the peptidase S41A family
AM608_RS00155	COG2223	nitrite transmembrane transporter activity
AM608_RS00160	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM608_RS00165	COG0138	bifunctional purine biosynthesis protein purh
AM608_RS00175	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM608_RS00180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM608_RS00195	COG4974	Belongs to the 'phage' integrase family
AM608_RS00210	COG2205	protein histidine kinase activity
AM608_RS00210	COG3292	Two component regulator propeller
AM608_RS00210	COG0745	RESPONSE REGULATOR receiver
AM608_RS00210	COG3292	Two component regulator propeller
AM608_RS00210	COG0745	RESPONSE REGULATOR receiver
AM608_RS00210	COG2205	protein histidine kinase activity
AM608_RS00215	COG0277	FAD linked oxidase domain protein
AM608_RS00225	COG1475	DNA binding
AM608_RS00230	COG1192	Involved in chromosome partitioning
AM608_RS00245	COG1012	belongs to the aldehyde dehydrogenase family
AM608_RS00270	COG0561	phosphatase activity
AM608_RS00285	COG1028	Short-chain dehydrogenase reductase Sdr
AM608_RS00295	COG4589	Belongs to the CDS family
AM608_RS00300	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM608_RS00305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM608_RS00315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AM608_RS00320	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AM608_RS00380	COG0275	rRNA processing
AM608_RS00395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM608_RS00405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM608_RS00410	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM608_RS00410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM608_RS00415	COG4948	Mandelate Racemase Muconate Lactonizing
AM608_RS00425	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM608_RS00430	COG0252	asparaginase activity
AM608_RS00440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM608_RS00440	COG2207	Transcriptional regulator
AM608_RS00445	COG3059	membrane
AM608_RS00450	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM608_RS00465	COG4589	Belongs to the CDS family
AM608_RS00470	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AM608_RS00485	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AM608_RS00490	COG0805	protein transport
AM608_RS00500	COG1137	ATPase activity
AM608_RS00505	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM608_RS00515	COG0205	6-phosphofructokinase activity
AM608_RS00530	COG1428	Deoxynucleoside kinase
AM608_RS00535	COG1522	sequence-specific DNA binding
AM608_RS00545	COG1132	(ABC) transporter
AM608_RS00555	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM608_RS00560	COG1739	Uncharacterized protein family UPF0029
AM608_RS00570	COG0295	cytidine deaminase activity
AM608_RS00580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM608_RS00600	COG1733	regulation of RNA biosynthetic process
AM608_RS00620	COG1741	Belongs to the pirin family
AM608_RS00665	COG2176	DNA-directed DNA polymerase activity
AM608_RS00680	COG1063	alcohol dehydrogenase
AM608_RS00700	COG3279	Response regulator of the LytR AlgR family
AM608_RS00705	COG3275	phosphorelay sensor kinase activity
AM608_RS00715	COG0702	epimerase
AM608_RS00740	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AM608_RS00750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM608_RS00755	COG0799	negative regulation of ribosome biogenesis
AM608_RS00770	COG0590	tRNA wobble adenosine to inosine editing
AM608_RS00780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM608_RS00785	COG2884	Cell division ATP-binding protein ftsE
AM608_RS00815	COG0517	IMP dehydrogenase activity
AM608_RS00815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM608_RS00820	COG0360	Binds together with S18 to 16S ribosomal RNA
AM608_RS00825	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM608_RS00830	COG0359	binds to the 23S rRNA
AM608_RS00840	COG1289	transmembrane transporter activity
AM608_RS00845	COG0009	L-threonylcarbamoyladenylate synthase
AM608_RS00875	COG2217	Heavy metal translocating P-type atpase
AM608_RS00890	COG2304	oxidoreductase activity
AM608_RS00905	COG0714	Associated with various cellular activities
AM608_RS00910	COG0626	cystathionine gamma-synthase activity
AM608_RS00925	COG1696	Membrane protein involved in D-alanine export
AM608_RS00935	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM608_RS00940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AM608_RS00945	COG1185	polyribonucleotide nucleotidyltransferase activity
AM608_RS00960	COG3177	Filamentation induced by cAMP protein fic
AM608_RS00965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM608_RS00985	COG2885	chlorophyll binding
AM608_RS00990	COG2885	chlorophyll binding
AM608_RS00995	COG0321	lipoyl(octanoyl) transferase activity
AM608_RS01000	COG2321	neutral zinc metallopeptidase
AM608_RS01020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM608_RS01025	COG2255	four-way junction helicase activity
AM608_RS01030	COG1187	pseudouridine synthase activity
AM608_RS01035	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AM608_RS01045	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AM608_RS01050	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM608_RS01055	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM608_RS01060	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM608_RS01065	COG0356	it plays a direct role in the translocation of protons across the membrane
AM608_RS01070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AM608_RS01090	COG0251	oxidation-reduction process
AM608_RS01095	COG0739	heme binding
AM608_RS01100	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AM608_RS01105	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AM608_RS01110	COG2226	methyltransferase
AM608_RS01125	COG0045	succinate-CoA ligase (ADP-forming) activity
AM608_RS01130	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM608_RS01145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM608_RS01155	COG0673	inositol 2-dehydrogenase activity
AM608_RS01165	COG0567	Dehydrogenase, E1 component
AM608_RS01180	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM608_RS01185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM608_RS01200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM608_RS01205	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AM608_RS01210	COG2226	methyltransferase
AM608_RS01240	COG0592	DNA-directed DNA polymerase activity
AM608_RS01245	COG1368	sulfuric ester hydrolase activity
AM608_RS01250	COG1078	dGTPase activity
AM608_RS01255	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM608_RS01260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM608_RS01260	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AM608_RS01265	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM608_RS01270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM608_RS01280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM608_RS01280	COG1333	cytochrome c biogenesis protein
AM608_RS01305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM608_RS01315	COG0534	Mate efflux family protein
AM608_RS01320	COG3591	Belongs to the peptidase S1B family
AM608_RS01330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM608_RS01345	COG1132	(ABC) transporter
AM608_RS01360	COG3594	Acyltransferase
AM608_RS01375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM608_RS01380	COG0577	efflux transmembrane transporter activity
AM608_RS01390	COG3951	Flagellar rod assembly protein muramidase FlgJ
AM608_RS01390	COG1705	Flagellar rod assembly protein muramidase FlgJ
AM608_RS01395	COG2890	protein-(glutamine-N5) methyltransferase activity
AM608_RS01400	COG2843	Capsule synthesis protein
AM608_RS01410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AM608_RS01420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM608_RS01425	COG2989	Protein conserved in bacteria
AM608_RS01430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM608_RS01445	COG0737	Belongs to the 5'-nucleotidase family
AM608_RS01485	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM608_RS01510	COG1252	NADH dehydrogenase
AM608_RS01525	COG3250	beta-galactosidase activity
AM608_RS01530	COG3119	arylsulfatase activity
AM608_RS01540	COG0681	Belongs to the peptidase S26 family
AM608_RS01545	COG0561	phosphatase activity
AM608_RS01550	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AM608_RS01565	COG2226	methyltransferase
AM608_RS01570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AM608_RS01575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM608_RS01595	COG1045	serine acetyltransferase
AM608_RS01605	COG0823	Involved in the tonB-independent uptake of proteins
AM608_RS01605	COG1506	peptidase
AM608_RS01620	COG4999	Histidine kinase
AM608_RS01620	COG3850	Histidine kinase
AM608_RS01620	COG4999	Histidine kinase
AM608_RS01620	COG3850	Histidine kinase
AM608_RS01620	COG3437	response regulator, receiver
AM608_RS01620	COG2205	protein histidine kinase activity
AM608_RS01620	COG2205	protein histidine kinase activity
AM608_RS01620	COG3437	response regulator, receiver
AM608_RS01640	COG0156	8-amino-7-oxononanoate synthase activity
AM608_RS01645	COG0463	Glycosyl transferase, family 2
AM608_RS01660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM608_RS01660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM608_RS01665	COG1288	antiporter activity
AM608_RS01680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM608_RS01685	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AM608_RS01710	COG0142	geranyltranstransferase activity
AM608_RS01715	COG0497	DNA recombination
AM608_RS01725	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM608_RS01725	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM608_RS01735	COG0433	COG0433 Predicted ATPase
AM608_RS01740	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM608_RS01745	COG2017	converts alpha-aldose to the beta-anomer
AM608_RS01760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM608_RS01770	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AM608_RS01775	COG0443	Heat shock 70 kDa protein
AM608_RS01780	COG0542	response to heat
AM608_RS01785	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM608_RS01790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM608_RS01790	COG0519	Catalyzes the synthesis of GMP from XMP
AM608_RS01800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM608_RS01850	COG1166	arginine decarboxylase activity
AM608_RS01860	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM608_RS01865	COG0857	belongs to the CobB CobQ family
AM608_RS01865	COG0280	phosphate acetyltransferase
AM608_RS01875	COG1899	peptidyl-lysine modification to peptidyl-hypusine
AM608_RS01890	COG0662	Cupin 2, conserved barrel domain protein
AM608_RS01890	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AM608_RS01905	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM608_RS01915	COG1349	DNA-binding transcription factor activity
AM608_RS01920	COG1393	Belongs to the ArsC family
AM608_RS01955	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AM608_RS01955	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AM608_RS01970	COG0339	signal peptide processing
AM608_RS01975	COG0606	chelatase, subunit chli
AM608_RS02000	COG4771	TonB-dependent receptor
AM608_RS02005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM608_RS02010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM608_RS02020	COG2356	endonuclease I
AM608_RS02035	COG0528	UMP kinase activity
AM608_RS02040	COG0233	cytoplasmic translational termination
AM608_RS02045	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM608_RS02050	COG1523	belongs to the glycosyl hydrolase 13 family
AM608_RS02070	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM608_RS02085	COG1522	sequence-specific DNA binding
AM608_RS02090	COG1401	restriction endodeoxyribonuclease activity
AM608_RS02100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM608_RS02105	COG0488	(ABC) transporter
AM608_RS02150	COG0471	metal ion transport
AM608_RS02155	COG1028	Short-chain dehydrogenase reductase Sdr
AM608_RS02170	COG0598	Magnesium transport protein CorA
AM608_RS02185	COG0357	Ribosomal RNA small subunit methyltransferase G
AM608_RS02195	COG0101	tRNA pseudouridine synthase activity
AM608_RS02205	COG4783	chaperone-mediated protein folding
AM608_RS02210	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AM608_RS02215	COG0824	Thioesterase
AM608_RS02220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM608_RS02225	COG0686	Belongs to the AlaDH PNT family
AM608_RS02255	COG0482	sulfurtransferase activity
AM608_RS02270	COG0514	ATP-dependent DNA helicase (RecQ)
AM608_RS02275	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AM608_RS02280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AM608_RS02290	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AM608_RS02295	COG1970	mechanosensitive ion channel activity
AM608_RS02300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM608_RS02315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM608_RS02320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AM608_RS02325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM608_RS02335	COG1862	Preprotein translocase
AM608_RS02340	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM608_RS02350	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM608_RS02360	COG0284	orotidine-5'-phosphate decarboxylase activity
AM608_RS02370	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM608_RS02375	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM608_RS02385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM608_RS02405	COG0811	peptide transport
AM608_RS02410	COG0848	biopolymer transport protein
AM608_RS02425	COG2239	Acts as a magnesium transporter
AM608_RS02430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM608_RS02450	COG0343	queuine tRNA-ribosyltransferase activity
AM608_RS02455	COG2733	membrane
AM608_RS02470	COG0116	Belongs to the methyltransferase superfamily
AM608_RS02470	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AM608_RS02475	COG0217	transcriptional regulatory protein
AM608_RS02485	COG0688	phosphatidylethanolamine metabolic process
AM608_RS02490	COG2264	protein methyltransferase activity
AM608_RS02505	COG3590	peptidase
AM608_RS02510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM608_RS02515	COG0488	(ABC) transporter
AM608_RS02530	COG0009	L-threonylcarbamoyladenylate synthase
AM608_RS02535	COG2050	protein possibly involved in aromatic compounds catabolism
AM608_RS02560	COG0544	peptidyl-prolyl cis-trans isomerase activity
AM608_RS02570	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AM608_RS02585	COG0336	Belongs to the RNA methyltransferase TrmD family
AM608_RS02590	COG0318	PFAM AMP-dependent synthetase and ligase
AM608_RS02625	COG0786	glutamate:sodium symporter activity
AM608_RS02630	COG0363	glucosamine-6-phosphate deaminase activity
AM608_RS02635	COG0215	cysteine-tRNA ligase activity
AM608_RS02645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM608_RS02655	COG0792	nuclease activity
AM608_RS02665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM608_RS02685	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AM608_RS02690	COG1193	negative regulation of DNA recombination
AM608_RS02700	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AM608_RS02705	COG1295	ribonuclease BN
AM608_RS02710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM608_RS02720	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AM608_RS02725	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AM608_RS02735	COG4152	abc transporter atp-binding protein
AM608_RS02740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AM608_RS02750	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM608_RS02755	COG0010	Belongs to the arginase family
AM608_RS02765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AM608_RS02770	COG0436	Aminotransferase
AM608_RS02785	COG1335	isochorismatase
AM608_RS02795	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM608_RS02800	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM608_RS02820	COG2095	MarC family integral membrane protein
AM608_RS02825	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AM608_RS02830	COG0517	IMP dehydrogenase activity
AM608_RS02830	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AM608_RS02830	COG0617	tRNA 3'-terminal CCA addition
AM608_RS02845	COG0702	epimerase
AM608_RS02850	COG1629	transport
AM608_RS02855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM608_RS02885	COG1408	metallophosphoesterase
AM608_RS02900	COG0438	transferase activity, transferring glycosyl groups
AM608_RS02915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM608_RS02930	COG0481	GTPase activity
AM608_RS02980	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AM608_RS02990	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AM608_RS03000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM608_RS03005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM608_RS03015	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AM608_RS03025	COG0501	Belongs to the peptidase M48B family
AM608_RS03030	COG0542	response to heat
AM608_RS03035	COG0791	NLP P60 protein
AM608_RS03040	COG2333	competence protein COMEC
AM608_RS03040	COG0658	competence protein
AM608_RS03060	COG0022	dehydrogenase e1 component
AM608_RS03075	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM608_RS03080	COG1760	l-serine dehydratase
AM608_RS03095	COG0588	phosphoglycerate mutase activity
AM608_RS03100	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM608_RS03105	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM608_RS03110	COG0247	lactate metabolic process
AM608_RS03110	COG2181	nitrate reductase activity
AM608_RS03115	COG0488	(ABC) transporter
AM608_RS03120	COG0826	peptidase U32
AM608_RS03145	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AM608_RS03155	COG3876	Protein conserved in bacteria
AM608_RS03170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AM608_RS03180	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AM608_RS03205	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AM608_RS03225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AM608_RS03230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AM608_RS03235	COG0552	protein localization to endoplasmic reticulum
AM608_RS03250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM608_RS03270	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AM608_RS03280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM608_RS03285	COG1381	Involved in DNA repair and RecF pathway recombination
AM608_RS03295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM608_RS03305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM608_RS03325	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM608_RS03340	COG0167	dihydroorotate dehydrogenase activity
AM608_RS03345	COG1561	YicC-like family, N-terminal region
AM608_RS03350	COG0194	GDP metabolic process
AM608_RS03355	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AM608_RS03360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM608_RS03365	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM608_RS03380	COG1309	transcriptional regulator
AM608_RS03390	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM608_RS03400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM608_RS03405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM608_RS03425	COG2177	Part of the ABC transporter FtsEX involved in
AM608_RS03435	COG1968	undecaprenyl-diphosphatase activity
AM608_RS03440	COG0671	phosphoesterase, PA-phosphatase related
AM608_RS03445	COG2226	methyltransferase
AM608_RS03450	COG1477	protein flavinylation
AM608_RS03455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM608_RS03475	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM608_RS03510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM608_RS03515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM608_RS03520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM608_RS03530	COG0569	domain protein
AM608_RS03535	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM608_RS03540	COG0668	transmembrane transport
AM608_RS03545	COG0517	IMP dehydrogenase activity
AM608_RS03545	COG0516	GMP reductase activity
AM608_RS03555	COG2824	Alkylphosphonate utilization operon protein PhnA
AM608_RS03570	COG0326	Molecular chaperone. Has ATPase activity
AM608_RS03575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM608_RS03595	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM608_RS03600	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM608_RS03610	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AM608_RS03620	COG0439	Biotin carboxylase
AM608_RS03625	COG0511	ligase activity, forming carbon-carbon bonds
AM608_RS03630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM608_RS03650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM608_RS03655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AM608_RS03670	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM608_RS03675	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM608_RS03680	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM608_RS03685	COG1805	sodium ion transport
AM608_RS03855	COG0302	gtp cyclohydrolase
AM608_RS03860	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM608_RS03870	COG0427	acetyl-CoA hydrolase
AM608_RS03885	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM608_RS03890	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM608_RS03895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AM608_RS03905	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AM608_RS03915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM608_RS03925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AM608_RS03955	COG1380	Effector of murein hydrolase LrgA
AM608_RS03960	COG1346	cytolysis
AM608_RS03965	COG0335	large ribosomal subunit rRNA binding
AM608_RS03970	COG2176	DNA-directed DNA polymerase activity
AM608_RS03980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM608_RS03985	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AM608_RS03995	COG3340	Belongs to the peptidase S51 family
AM608_RS04010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM608_RS04015	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM608_RS04020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM608_RS04030	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AM608_RS04035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM608_RS04040	COG0400	carboxylic ester hydrolase activity
AM608_RS04045	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AM608_RS04055	COG1215	transferase activity, transferring glycosyl groups
AM608_RS04075	COG0012	GTP binding
AM608_RS04080	COG0149	triose-phosphate isomerase activity
AM608_RS04085	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AM608_RS04095	COG0228	four-way junction DNA binding
AM608_RS04100	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AM608_RS04110	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AM608_RS04115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM608_RS04120	COG0612	Peptidase, M16
AM608_RS04125	COG0612	Peptidase, M16
AM608_RS04130	COG0191	fructose-bisphosphate aldolase activity
AM608_RS04140	COG0842	Transport permease protein
AM608_RS04145	COG0842	Transport permease protein
AM608_RS04150	COG1131	(ABC) transporter
AM608_RS04155	COG1131	(ABC) transporter
AM608_RS04160	COG2226	methyltransferase
AM608_RS04195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM608_RS04205	COG0539	negative regulation of cytoplasmic translation
AM608_RS04210	COG1217	gtp-binding protein TYPA
AM608_RS04255	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM608_RS04265	COG4452	Inner membrane protein CreD
AM608_RS04280	COG0612	Peptidase, M16
AM608_RS04305	COG0492	ferredoxin-NADP+ reductase activity
AM608_RS04315	COG2270	Major facilitator Superfamily
AM608_RS04340	COG0772	Belongs to the SEDS family
AM608_RS04345	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AM608_RS04350	COG0504	CTP synthase activity
AM608_RS04355	COG0706	membrane insertase activity
AM608_RS04365	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AM608_RS04370	COG0490	domain, Protein
AM608_RS04370	COG0471	metal ion transport
AM608_RS04380	COG1104	cysteine desulfurase activity
AM608_RS04390	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AM608_RS04395	COG1136	(ABC) transporter
AM608_RS04415	COG1663	tetraacyldisaccharide 4'-kinase activity
AM608_RS04425	COG2204	response regulator
AM608_RS04430	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AM608_RS04440	COG2267	carboxylic ester hydrolase activity
AM608_RS04455	COG0018	arginyl-trna synthetase
AM608_RS04465	COG0509	glycine decarboxylation via glycine cleavage system
AM608_RS04485	COG0305	Participates in initiation and elongation during chromosome replication
AM608_RS04510	COG3250	beta-galactosidase activity
AM608_RS04530	COG0702	epimerase
AM608_RS04535	COG5434	Belongs to the glycosyl hydrolase 28 family
AM608_RS04540	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AM608_RS04560	COG0242	peptide deformylase activity
AM608_RS04570	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AM608_RS04605	COG4974	Belongs to the 'phage' integrase family
AM608_RS04630	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM608_RS04660	COG0745	RESPONSE REGULATOR receiver
AM608_RS04660	COG2205	protein histidine kinase activity
AM608_RS04660	COG3292	Two component regulator propeller
AM608_RS04675	COG1621	beta-fructofuranosidase activity
AM608_RS04690	COG0702	epimerase
AM608_RS04695	COG1629	transport
AM608_RS04700	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AM608_RS04720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AM608_RS04735	COG2351	hydroxyisourate hydrolase activity
AM608_RS04740	COG0463	Glycosyl transferase, family 2
AM608_RS04750	COG0386	Belongs to the glutathione peroxidase family
AM608_RS04765	COG1053	succinate dehydrogenase
AM608_RS04775	COG2217	Heavy metal translocating P-type atpase
AM608_RS04800	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM608_RS04810	COG2837	iron assimilation
AM608_RS04830	COG1074	ATP-dependent DNA helicase activity
AM608_RS04845	COG0714	Associated with various cellular activities
AM608_RS04850	COG0673	inositol 2-dehydrogenase activity
AM608_RS04855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM608_RS04880	COG0811	peptide transport
AM608_RS04890	COG0252	asparaginase activity
AM608_RS04900	COG0084	hydrolase, TatD family'
AM608_RS04915	COG4206	TonB-dependent receptor
AM608_RS04915	COG1629	transport
AM608_RS04925	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AM608_RS04935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM608_RS04945	COG0505	Belongs to the CarA family
AM608_RS04955	COG0148	phosphopyruvate hydratase activity
AM608_RS04965	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM608_RS04965	COG0321	lipoyl(octanoyl) transferase activity
AM608_RS04980	COG0527	aspartate kinase activity
AM608_RS04985	COG0124	histidyl-tRNA synthetase
AM608_RS04990	COG3956	TIGRFAM MazG family protein
AM608_RS05005	COG3340	Belongs to the peptidase S51 family
AM608_RS05060	COG3118	belongs to the thioredoxin family
AM608_RS05070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM608_RS05115	COG0632	four-way junction helicase activity
AM608_RS05140	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AM608_RS05145	COG0459	protein refolding
AM608_RS05190	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AM608_RS05205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM608_RS05210	COG0719	Fe-S assembly protein
AM608_RS05235	COG0783	Belongs to the Dps family
AM608_RS05240	COG1132	(ABC) transporter
AM608_RS05245	COG1674	ftsk spoiiie
AM608_RS05250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM608_RS05255	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AM608_RS05290	COG2081	HI0933 family
AM608_RS05295	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM608_RS05300	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AM608_RS05300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM608_RS05305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM608_RS05310	COG0463	Glycosyl transferase, family 2
AM608_RS05310	COG1216	Glycosyl transferase, family 2
AM608_RS05315	COG1162	GTPase activity
AM608_RS05340	COG0366	Alpha amylase catalytic
AM608_RS05345	COG3022	response to hydroperoxide
AM608_RS05375	COG0540	Belongs to the ATCase OTCase family
AM608_RS05395	COG0017	Asparaginyl-tRNA synthetase
AM608_RS05405	COG1696	Membrane protein involved in D-alanine export
AM608_RS05415	COG0488	(ABC) transporter
AM608_RS05430	COG4974	Belongs to the 'phage' integrase family
AM608_RS05460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM608_RS05465	COG1136	(ABC) transporter
AM608_RS05495	COG3275	phosphorelay sensor kinase activity
AM608_RS05500	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AM608_RS05525	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM608_RS05535	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM608_RS05545	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM608_RS05550	COG4717	serine-type aminopeptidase activity
AM608_RS05560	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AM608_RS05570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM608_RS05580	COG0527	aspartate kinase activity
AM608_RS05580	COG0460	homoserine dehydrogenase
AM608_RS05585	COG0456	acetyltransferase
AM608_RS05585	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM608_RS05590	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM608_RS05595	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AM608_RS05605	COG0259	pyridoxamine-phosphate oxidase activity
AM608_RS05610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM608_RS05630	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AM608_RS05635	COG0081	regulation of translation
AM608_RS05640	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AM608_RS05645	COG0222	ribosome binding
AM608_RS05660	COG0085	RNA polymerase activity
AM608_RS05670	COG0456	acetyltransferase
AM608_RS05680	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AM608_RS05715	COG3119	arylsulfatase activity
AM608_RS05730	COG4771	TonB-dependent receptor
AM608_RS05735	COG0702	epimerase
AM608_RS05750	COG1472	Belongs to the glycosyl hydrolase 3 family
AM608_RS05755	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AM608_RS05760	COG2986	histidine ammonia-lyase
AM608_RS05765	COG2706	6-phosphogluconolactonase activity
AM608_RS05775	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AM608_RS05785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM608_RS05795	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AM608_RS05800	COG0484	heat shock protein binding
AM608_RS05815	COG1482	cell wall glycoprotein biosynthetic process
AM608_RS05820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM608_RS05845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM608_RS05860	COG0653	protein targeting
AM608_RS05875	COG0671	phosphoesterase, PA-phosphatase related
AM608_RS05895	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AM608_RS05945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM608_RS05955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM608_RS05980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AM608_RS05990	COG3104	oligopeptide transport
AM608_RS05995	COG1917	Cupin 2, conserved barrel domain protein
AM608_RS05995	COG4977	sequence-specific DNA binding
AM608_RS06015	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM608_RS06020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM608_RS06035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM608_RS06040	COG4771	TonB-dependent receptor
AM608_RS06080	COG1950	PFAM Membrane protein of
AM608_RS06085	COG0596	Alpha beta hydrolase
AM608_RS06095	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AM608_RS06100	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM608_RS06110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM608_RS06110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM608_RS06155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM608_RS06160	COG0247	lactate metabolic process
AM608_RS06160	COG2181	nitrate reductase activity
AM608_RS06190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM608_RS06195	COG0300	oxidoreductase activity
AM608_RS06215	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AM608_RS06225	COG1575	Belongs to the MenA family. Type 1 subfamily
AM608_RS06230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AM608_RS06240	COG0563	adenylate kinase activity
AM608_RS06245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AM608_RS06255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM608_RS06320	COG0564	pseudouridine synthase activity
AM608_RS06335	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AM608_RS06350	COG2814	Major facilitator Superfamily
AM608_RS06365	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM608_RS06405	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AM608_RS06415	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
AM608_RS06415	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
AM608_RS06420	COG1490	D-aminoacyl-tRNA deacylase activity
AM608_RS06450	COG1620	l-lactate permease
AM608_RS06470	COG0037	tRNA processing
AM608_RS06510	COG3250	beta-galactosidase activity
AM608_RS06520	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM608_RS06540	COG0720	synthase
AM608_RS06555	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM608_RS06585	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AM608_RS06610	COG5652	VanZ like family
AM608_RS06625	COG0346	lactoylglutathione lyase activity
AM608_RS06640	COG2315	Protein conserved in bacteria
AM608_RS06700	COG1082	Xylose isomerase domain protein TIM barrel
AM608_RS06705	COG1629	transport
AM608_RS06705	COG4206	TonB-dependent receptor
AM608_RS06710	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM608_RS06730	COG3951	Flagellar rod assembly protein muramidase FlgJ
AM608_RS06730	COG1705	Flagellar rod assembly protein muramidase FlgJ
AM608_RS06860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM608_RS06880	COG4771	TonB-dependent receptor
AM608_RS06890	COG0516	GMP reductase activity
AM608_RS06890	COG0517	IMP dehydrogenase activity
AM608_RS06905	COG0450	alkyl hydroperoxide reductase
AM608_RS06945	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AM608_RS06955	COG3177	Filamentation induced by cAMP protein fic
AM608_RS06960	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AM608_RS06965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM608_RS06970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM608_RS06995	COG4771	TonB-dependent receptor
AM608_RS07015	COG1629	transport
AM608_RS07015	COG4206	TonB-dependent receptor
AM608_RS07025	COG0758	DNA mediated transformation
AM608_RS07025	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM608_RS07030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM608_RS07045	COG0602	queuosine metabolic process
AM608_RS07060	COG0180	Tryptophanyl-tRNA synthetase
AM608_RS07070	COG0306	phosphate transporter
AM608_RS07075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM608_RS07080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM608_RS07085	COG1506	peptidase
AM608_RS07085	COG0823	Involved in the tonB-independent uptake of proteins
AM608_RS07100	COG0756	dUTP diphosphatase activity
AM608_RS07135	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM608_RS07145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM608_RS07170	COG1234	tRNA 3'-trailer cleavage
AM608_RS07180	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AM608_RS07200	COG1960	acyl-CoA dehydrogenase activity
AM608_RS07210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM608_RS07230	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AM608_RS07235	COG0052	Belongs to the universal ribosomal protein uS2 family
AM608_RS07240	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM608_RS07245	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AM608_RS07250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM608_RS07270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM608_RS07280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM608_RS07295	COG1086	Polysaccharide biosynthesis protein
AM608_RS07300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM608_RS07310	COG2089	acid synthase
AM608_RS07315	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM608_RS07320	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM608_RS07325	COG1083	cytidylyl-transferase
AM608_RS07335	COG1028	Short-chain dehydrogenase reductase Sdr
AM608_RS07380	COG1216	Glycosyl transferase, family 2
AM608_RS07435	COG0471	metal ion transport
AM608_RS07445	COG1418	mRNA catabolic process
AM608_RS07460	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM608_RS07475	COG0698	ribose 5-phosphate isomerase
AM608_RS07485	COG1702	phosphate starvation-inducible protein PhoH
AM608_RS07505	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AM608_RS07510	COG1519	Transferase
AM608_RS07530	COG4771	TonB-dependent receptor
AM608_RS07550	COG0022	dehydrogenase e1 component
AM608_RS07550	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM608_RS07560	COG0175	sulfate reduction
AM608_RS07565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM608_RS07575	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM608_RS07600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM608_RS07605	COG1505	serine-type exopeptidase activity
AM608_RS07635	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AM608_RS07650	COG0166	Belongs to the GPI family
AM608_RS07690	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM608_RS07695	COG0557	exoribonuclease II activity
AM608_RS07755	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AM608_RS07765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM608_RS07775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM608_RS07785	COG2966	Psort location CytoplasmicMembrane, score
AM608_RS07790	COG0358	DNA primase activity
AM608_RS07805	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AM608_RS07830	COG2003	Belongs to the UPF0758 family
AM608_RS07835	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM608_RS07845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM608_RS07845	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM608_RS07850	COG1285	pathogenesis
AM608_RS07865	COG1082	Xylose isomerase domain protein TIM barrel
AM608_RS07880	COG0702	epimerase
AM608_RS07885	COG4771	TonB-dependent receptor
AM608_RS07910	COG2151	metal-sulfur cluster biosynthetic enzyme
AM608_RS07915	COG2166	iron-sulfur cluster assembly
AM608_RS07925	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AM608_RS08045	COG1132	(ABC) transporter
AM608_RS08050	COG0028	Belongs to the TPP enzyme family
AM608_RS08070	COG2066	Belongs to the glutaminase family
AM608_RS08080	COG0629	single-stranded DNA binding
AM608_RS08090	COG0393	Putative heavy-metal-binding
AM608_RS08100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM608_RS08135	COG1028	Short-chain dehydrogenase reductase Sdr
AM608_RS08155	COG0445	tRNA wobble uridine modification
AM608_RS08165	COG0469	pyruvate kinase activity
AM608_RS08175	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM608_RS08205	COG1629	transport
AM608_RS08225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM608_RS08260	COG0668	transmembrane transport
AM608_RS08270	COG1114	Component of the transport system for branched-chain amino acids
AM608_RS08280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM608_RS08280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM608_RS08300	COG3588	fructose-bisphosphate aldolase
AM608_RS08310	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM608_RS08315	COG1214	PFAM Peptidase M22, glycoprotease
AM608_RS08350	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM608_RS08350	COG1918	ferrous iron import across plasma membrane
AM608_RS08355	COG4974	Belongs to the 'phage' integrase family
AM608_RS08380	COG3104	oligopeptide transport
AM608_RS08385	COG1506	peptidase
AM608_RS08385	COG0823	Involved in the tonB-independent uptake of proteins
AM608_RS08390	COG0077	Prephenate dehydratase
AM608_RS08390	COG1605	Chorismate mutase
AM608_RS08400	COG2244	polysaccharide biosynthetic process
AM608_RS08410	COG1215	transferase activity, transferring glycosyl groups
AM608_RS08490	COG3645	SOS response
AM608_RS08515	COG0495	leucyl-tRNA aminoacylation
AM608_RS08540	COG0438	transferase activity, transferring glycosyl groups
AM608_RS08585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM608_RS08590	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AM608_RS08595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AM608_RS08600	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AM608_RS08610	COG3041	Addiction module toxin RelE StbE family
AM608_RS08620	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AM608_RS08630	COG0484	heat shock protein binding
AM608_RS08640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM608_RS08645	COG0300	oxidoreductase activity
AM608_RS08650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM608_RS08675	COG2205	protein histidine kinase activity
AM608_RS08675	COG3292	Two component regulator propeller
AM608_RS08675	COG0745	RESPONSE REGULATOR receiver
AM608_RS08680	COG3250	beta-galactosidase activity
AM608_RS08705	COG3250	beta-galactosidase activity
AM608_RS08720	COG0702	epimerase
AM608_RS08735	COG1629	transport
AM608_RS08735	COG4206	TonB-dependent receptor
AM608_RS08745	COG0193	aminoacyl-tRNA hydrolase activity
AM608_RS08755	COG1943	Transposase
AM608_RS08775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM608_RS08795	COG2373	Large extracellular alpha-helical protein
AM608_RS08855	COG0175	sulfate reduction
AM608_RS08860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM608_RS08870	COG0616	signal peptide processing
AM608_RS08875	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM608_RS08890	COG0006	proline dipeptidase activity
AM608_RS08895	COG1854	S-ribosylhomocysteine lyase activity
AM608_RS08950	COG0501	Belongs to the peptidase M48B family
AM608_RS08955	COG1704	LemA family
AM608_RS08960	COG1091	dTDP-4-dehydrorhamnose reductase activity
AM608_RS08995	COG2755	lipolytic protein G-D-S-L family
AM608_RS08995	COG0657	acetylesterase activity
AM608_RS09005	COG0861	Integral membrane protein TerC family
AM608_RS09035	COG4221	oxidoreductase activity
AM608_RS09055	COG0396	ATPase activity
AM608_RS09060	COG0719	Fe-S assembly protein
AM608_RS09070	COG0470	DNA polymerase III
AM608_RS09085	COG3829	transcription factor binding
AM608_RS09090	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM608_RS09110	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AM608_RS09150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM608_RS09160	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AM608_RS09175	COG5000	phosphorelay sensor kinase activity
AM608_RS09190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM608_RS09205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM608_RS09215	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AM608_RS09220	COG3005	denitrification pathway
AM608_RS09235	COG3561	AntA/AntB antirepressor
AM608_RS09375	COG0740	serine-type endopeptidase activity
AM608_RS09470	COG1629	transport
AM608_RS09470	COG4206	TonB-dependent receptor
AM608_RS09475	COG0702	epimerase
AM608_RS09500	COG4771	TonB-dependent receptor
AM608_RS09505	COG0702	epimerase
AM608_RS09525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM608_RS09530	COG0288	reversible hydration of carbon dioxide
AM608_RS09540	COG0702	epimerase
AM608_RS09575	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AM608_RS09580	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM608_RS09605	COG0489	protein tyrosine kinase activity
AM608_RS09610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM608_RS09610	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM608_RS09625	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AM608_RS09630	COG0049	tRNA binding
AM608_RS09635	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM608_RS09640	COG0051	transcription antitermination factor activity, RNA binding
AM608_RS09645	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AM608_RS09650	COG0088	Forms part of the polypeptide exit tunnel
AM608_RS09655	COG0089	rRNA binding
AM608_RS09660	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AM608_RS09665	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM608_RS09670	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AM608_RS09675	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AM608_RS09680	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM608_RS09685	COG0255	Belongs to the universal ribosomal protein uL29 family
AM608_RS09690	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AM608_RS09695	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AM608_RS09700	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AM608_RS09705	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AM608_RS09710	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AM608_RS09715	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AM608_RS09720	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AM608_RS09725	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AM608_RS09730	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AM608_RS09735	COG1841	ribosomal large subunit assembly
AM608_RS09740	COG0200	Binds to the 23S rRNA
AM608_RS09745	COG0201	protein transport
AM608_RS09750	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AM608_RS09755	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AM608_RS09760	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AM608_RS09765	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AM608_RS09770	COG0202	RNA polymerase activity
AM608_RS09775	COG0203	ribosomal protein L17
AM608_RS09780	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AM608_RS09935	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AM608_RS09940	COG0195	Participates in both transcription termination and antitermination
AM608_RS09940	COG2251	uridine kinase activity
AM608_RS09945	COG0779	Required for maturation of 30S ribosomal subunits
AM608_RS09960	COG0339	signal peptide processing
AM608_RS09970	COG0113	porphobilinogen synthase activity
AM608_RS09980	COG1253	flavin adenine dinucleotide binding
AM608_RS10000	COG0322	excinuclease ABC activity
AM608_RS10055	COG1234	tRNA 3'-trailer cleavage
AM608_RS10065	COG4941	Belongs to the sigma-70 factor family
AM608_RS10100	COG1234	tRNA 3'-trailer cleavage
AM608_RS10105	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM608_RS10110	COG0656	L-ascorbic acid biosynthetic process
AM608_RS10125	COG0789	Transcriptional regulator
AM608_RS10135	COG1028	Short-chain dehydrogenase reductase Sdr
AM608_RS10165	COG1114	Component of the transport system for branched-chain amino acids
AM608_RS10230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM608_RS10235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM608_RS10240	COG0571	ribonuclease III activity
AM608_RS10250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM608_RS10255	COG0126	phosphoglycerate kinase activity
AM608_RS10290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AM608_RS10295	COG1981	membrane
AM608_RS10310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AM608_RS10330	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AM608_RS10335	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM608_RS10345	COG4771	TonB-dependent receptor
AM608_RS10350	COG0702	epimerase
AM608_RS10375	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AM608_RS10380	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM608_RS10395	COG0492	ferredoxin-NADP+ reductase activity
AM608_RS10425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM608_RS10450	COG2184	nucleotidyltransferase activity
AM608_RS10460	COG1160	GTP binding
AM608_RS10465	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM608_RS10470	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AM608_RS10475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM608_RS10485	COG1022	Amp-dependent synthetase and ligase
AM608_RS10490	COG0196	riboflavin kinase activity
AM608_RS10510	COG0423	glycine-tRNA ligase activity
AM608_RS10520	COG1040	competence protein
AM608_RS10535	COG1610	YqeY-like protein
AM608_RS10555	COG1012	belongs to the aldehyde dehydrogenase family
AM608_RS10565	COG4771	TonB-dependent receptor
AM608_RS10595	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM608_RS10600	COG0501	Belongs to the peptidase M48B family
AM608_RS10635	COG0424	maF-like protein
AM608_RS10660	COG1792	Involved in formation and maintenance of cell shape
AM608_RS10665	COG1077	Cell shape determining protein MreB Mrl
AM608_RS10675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AM608_RS10680	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AM608_RS10685	COG3530	Putative quorum-sensing-regulated virulence factor
AM608_RS10690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM608_RS10700	COG2171	N-acyltransferase activity
AM608_RS10705	COG0525	valine-tRNA ligase activity
AM608_RS10715	COG0420	3'-5' exonuclease activity
AM608_RS10720	COG0116	Belongs to the methyltransferase superfamily
AM608_RS10740	COG0437	4 iron, 4 sulfur cluster binding
AM608_RS10750	COG0237	dephospho-CoA kinase activity
AM608_RS10760	COG0287	Prephenate dehydrogenase
AM608_RS10785	COG2954	triphosphatase activity
AM608_RS10815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM608_RS10820	COG0556	nucleotide-excision repair
AM608_RS10825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM608_RS10885	COG0708	Exodeoxyribonuclease III
AM608_RS10890	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM608_RS10905	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AM608_RS10910	COG1834	amidinotransferase
AM608_RS10915	COG0181	hydroxymethylbilane synthase activity
AM608_RS10920	COG0187	DNA topoisomerase II activity
AM608_RS10940	COG1271	oxidase subunit
AM608_RS10945	COG1294	oxidase, subunit
AM608_RS10950	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AM608_RS10955	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AM608_RS10970	COG0745	RESPONSE REGULATOR receiver
AM608_RS10970	COG2205	protein histidine kinase activity
AM608_RS10970	COG3292	Two component regulator propeller
AM608_RS10980	COG0702	epimerase
AM608_RS10985	COG1629	transport
AM608_RS10990	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM608_RS11000	COG1774	PSP1 C-terminal conserved region
AM608_RS11010	COG1530	ribonuclease E activity
AM608_RS11015	COG0776	regulation of translation
AM608_RS11025	COG2204	response regulator
AM608_RS11030	COG1472	Belongs to the glycosyl hydrolase 3 family
AM608_RS11040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM608_RS11050	COG1629	transport
AM608_RS11060	COG0156	8-amino-7-oxononanoate synthase activity
AM608_RS11065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM608_RS11085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM608_RS11090	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM608_RS11095	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM608_RS11100	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AM608_RS11115	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM608_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
AM608_RS11150	COG0297	glycogen (starch) synthase activity
AM608_RS11155	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AM608_RS11160	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AM608_RS11165	COG2304	oxidoreductase activity
AM608_RS11175	COG0268	Binds directly to 16S ribosomal RNA
AM608_RS11210	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AM608_RS11220	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AM608_RS11225	COG2267	carboxylic ester hydrolase activity
AM608_RS11235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM608_RS11245	COG0840	transmembrane signaling receptor activity
AM608_RS11250	COG0840	transmembrane signaling receptor activity
AM608_RS11255	COG1022	Amp-dependent synthetase and ligase