locus-tag	class	description
B7G68_RS00015	COG0308	aminopeptidase N
B7G68_RS00020	COG0443	Heat shock 70 kDa protein
B7G68_RS00025	COG0484	heat shock protein binding
B7G68_RS00030	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B7G68_RS00050	COG0180	Tryptophanyl-tRNA synthetase
B7G68_RS00060	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B7G68_RS00065	COG0778	Nitroreductase
B7G68_RS00090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B7G68_RS00095	COG1702	phosphate starvation-inducible protein PhoH
B7G68_RS00105	COG1253	flavin adenine dinucleotide binding
B7G68_RS00110	COG0815	Transfers the fatty acyl group on membrane lipoproteins
B7G68_RS00115	COG1396	sequence-specific DNA binding
B7G68_RS00120	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B7G68_RS00130	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B7G68_RS00150	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B7G68_RS00175	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B7G68_RS00215	COG1280	lysine exporter protein (LysE YggA)
B7G68_RS00220	COG4774	siderophore transport
B7G68_RS00225	COG3128	pkhd-type hydroxylase
B7G68_RS00240	COG1648	precorrin-2 dehydrogenase activity
B7G68_RS00240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7G68_RS00270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7G68_RS00280	COG0314	molybdopterin synthase activity
B7G68_RS00300	COG0840	transmembrane signaling receptor activity
B7G68_RS00315	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B7G68_RS00320	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B7G68_RS00370	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7G68_RS00370	COG1024	Enoyl-CoA hydratase
B7G68_RS00375	COG0183	Belongs to the thiolase family
B7G68_RS00385	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS00390	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS00395	COG0789	Transcriptional regulator
B7G68_RS00415	COG0033	Phosphoglucomutase
B7G68_RS00420	COG0138	bifunctional purine biosynthesis protein purh
B7G68_RS00430	COG2311	Membrane
B7G68_RS00445	COG0433	COG0433 Predicted ATPase
B7G68_RS00450	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B7G68_RS00460	COG0697	spore germination
B7G68_RS00470	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS00470	COG3321	synthase
B7G68_RS00470	COG0604	alcohol dehydrogenase
B7G68_RS00480	COG2169	Transcriptional regulator
B7G68_RS00515	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B7G68_RS00520	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B7G68_RS00520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B7G68_RS00545	COG2095	MarC family integral membrane protein
B7G68_RS00550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7G68_RS00560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B7G68_RS00580	COG1228	amidohydrolase
B7G68_RS00590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7G68_RS00600	COG0531	amino acid
B7G68_RS00605	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B7G68_RS00640	COG1280	lysine exporter protein (LysE YggA)
B7G68_RS00680	COG0280	phosphate acetyltransferase
B7G68_RS00680	COG0281	malic enzyme
B7G68_RS00685	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B7G68_RS00705	COG0840	transmembrane signaling receptor activity
B7G68_RS00710	COG1846	Transcriptional regulator
B7G68_RS00715	COG5006	permease, DMT superfamily
B7G68_RS00720	COG5425	PFAM Usg family protein
B7G68_RS00725	COG0135	phosphoribosylanthranilate isomerase activity
B7G68_RS00730	COG0133	tryptophan synthase activity
B7G68_RS00745	COG0285	dihydrofolate synthase activity
B7G68_RS00760	COG1074	ATP-dependent DNA helicase activity
B7G68_RS00770	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B7G68_RS00775	COG3178	'Phosphotransferase
B7G68_RS00780	COG0802	atpase or kinase
B7G68_RS00785	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B7G68_RS00790	COG0494	nUDIX hydrolase
B7G68_RS00810	COG1053	succinate dehydrogenase
B7G68_RS00825	COG0633	Ferredoxin
B7G68_RS00920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7G68_RS00925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7G68_RS00925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7G68_RS00930	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B7G68_RS00935	COG2205	protein histidine kinase activity
B7G68_RS00940	COG0745	RESPONSE REGULATOR receiver
B7G68_RS00980	COG1086	Polysaccharide biosynthesis protein
B7G68_RS00990	COG0590	tRNA wobble adenosine to inosine editing
B7G68_RS00995	COG1187	pseudouridine synthase activity
B7G68_RS01005	COG3548	integral membrane protein
B7G68_RS01010	COG0742	ribosomal rna small subunit methyltransferase
B7G68_RS01020	COG2982	Protein involved in outer membrane biogenesis
B7G68_RS01055	COG1999	signal sequence binding
B7G68_RS01075	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B7G68_RS01085	COG0640	Transcriptional regulator
B7G68_RS01090	COG0514	ATP-dependent DNA helicase (RecQ)
B7G68_RS01110	COG1846	Transcriptional regulator
B7G68_RS01120	COG3040	lipid binding
B7G68_RS01130	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B7G68_RS01160	COG2205	protein histidine kinase activity
B7G68_RS01165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B7G68_RS01175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7G68_RS01180	COG2962	Rard protein
B7G68_RS01185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B7G68_RS01195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7G68_RS01195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7G68_RS01205	COG0183	Belongs to the thiolase family
B7G68_RS01210	COG4771	TonB-dependent receptor
B7G68_RS01220	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B7G68_RS01230	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS01260	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B7G68_RS01270	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B7G68_RS01280	COG2076	Multidrug Resistance protein
B7G68_RS01305	COG0793	Belongs to the peptidase S41A family
B7G68_RS01315	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B7G68_RS01320	COG0799	negative regulation of ribosome biogenesis
B7G68_RS01325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B7G68_RS01330	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B7G68_RS01390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B7G68_RS01395	COG0753	catalase activity
B7G68_RS01415	COG5265	(ABC) transporter
B7G68_RS01420	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
B7G68_RS01435	COG2326	polyphosphate kinase activity
B7G68_RS01455	COG3104	oligopeptide transport
B7G68_RS01465	COG0312	modulator of DNA gyrase
B7G68_RS01490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7G68_RS01495	COG0109	protoheme IX farnesyltransferase activity
B7G68_RS01500	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
B7G68_RS01515	COG3346	SURF1 family
B7G68_RS01525	COG0612	Peptidase, M16
B7G68_RS01530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7G68_RS01550	COG1846	Transcriptional regulator
B7G68_RS01560	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS01575	COG0009	L-threonylcarbamoyladenylate synthase
B7G68_RS01610	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS01630	COG1994	Peptidase M50
B7G68_RS01635	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS01675	COG0330	HflC and HflK could
B7G68_RS01685	COG1131	(ABC) transporter
B7G68_RS01690	COG0842	Transport permease protein
B7G68_RS01700	COG0702	epimerase
B7G68_RS01710	COG1733	regulation of RNA biosynthetic process
B7G68_RS01725	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B7G68_RS01740	COG0840	transmembrane signaling receptor activity
B7G68_RS01745	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B7G68_RS01760	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B7G68_RS01780	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B7G68_RS01785	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B7G68_RS01790	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B7G68_RS01795	COG0356	it plays a direct role in the translocation of protons across the membrane
B7G68_RS01835	COG1194	a g-specific adenine glycosylase
B7G68_RS01880	COG2818	Glycosylase
B7G68_RS01890	COG0354	folic acid binding
B7G68_RS01905	COG4941	Belongs to the sigma-70 factor family
B7G68_RS01910	COG3795	YCII-related domain
B7G68_RS01920	COG0318	PFAM AMP-dependent synthetase and ligase
B7G68_RS01930	COG0028	Belongs to the TPP enzyme family
B7G68_RS01945	COG1846	Transcriptional regulator
B7G68_RS01950	COG1024	Enoyl-CoA hydratase
B7G68_RS01960	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS01990	COG0494	nUDIX hydrolase
B7G68_RS01995	COG0617	tRNA 3'-terminal CCA addition
B7G68_RS02000	COG0519	Catalyzes the synthesis of GMP from XMP
B7G68_RS02000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B7G68_RS02005	COG1309	transcriptional regulator
B7G68_RS02035	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
B7G68_RS02045	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS02070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7G68_RS02080	COG0347	Belongs to the P(II) protein family
B7G68_RS02115	COG0167	dihydroorotate dehydrogenase activity
B7G68_RS02125	COG5000	phosphorelay sensor kinase activity
B7G68_RS02135	COG0405	Gamma-glutamyltransferase
B7G68_RS02180	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B7G68_RS02190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B7G68_RS02220	COG0745	RESPONSE REGULATOR receiver
B7G68_RS02225	COG0643	Histidine kinase
B7G68_RS02225	COG2198	Histidine kinase
B7G68_RS02230	COG0835	chemotaxis
B7G68_RS02235	COG0840	transmembrane signaling receptor activity
B7G68_RS02240	COG0840	transmembrane signaling receptor activity
B7G68_RS02245	COG0840	transmembrane signaling receptor activity
B7G68_RS02250	COG0835	chemotaxis
B7G68_RS02255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B7G68_RS02260	COG2201	protein-glutamate methylesterase activity
B7G68_RS02280	COG2226	methyltransferase
B7G68_RS02360	COG4974	Belongs to the 'phage' integrase family
B7G68_RS02375	COG0596	Alpha beta hydrolase
B7G68_RS02380	COG1335	isochorismatase
B7G68_RS02405	COG1621	beta-fructofuranosidase activity
B7G68_RS02415	COG1609	Transcriptional regulator
B7G68_RS02425	COG0657	acetylesterase activity
B7G68_RS02435	COG2211	Major facilitator Superfamily
B7G68_RS02455	COG4771	TonB-dependent receptor
B7G68_RS02460	COG2272	Belongs to the type-B carboxylesterase lipase family
B7G68_RS02465	COG1940	carbohydrate kinase activity
B7G68_RS02485	COG4771	TonB-dependent receptor
B7G68_RS02490	COG4771	TonB-dependent receptor
B7G68_RS02505	COG1473	amidohydrolase
B7G68_RS02515	COG1595	DNA-templated transcription, initiation
B7G68_RS02585	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7G68_RS02590	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B7G68_RS02595	COG0297	glycogen (starch) synthase activity
B7G68_RS02605	COG0110	maltose O-acetyltransferase activity
B7G68_RS02610	COG0438	transferase activity, transferring glycosyl groups
B7G68_RS02615	COG2244	polysaccharide biosynthetic process
B7G68_RS02625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7G68_RS02650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7G68_RS02650	COG3453	Protein conserved in bacteria
B7G68_RS02660	COG0564	pseudouridine synthase activity
B7G68_RS02665	COG4771	TonB-dependent receptor
B7G68_RS02675	COG1280	lysine exporter protein (LysE YggA)
B7G68_RS02685	COG3739	integral membrane protein
B7G68_RS02690	COG0302	gtp cyclohydrolase
B7G68_RS02700	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS02745	COG0463	Glycosyl transferase, family 2
B7G68_RS02755	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B7G68_RS02765	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B7G68_RS02765	COG2857	Cytochrome c1
B7G68_RS02770	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B7G68_RS02770	COG2857	Cytochrome c1
B7G68_RS02790	COG0412	Dienelactone hydrolase
B7G68_RS02800	COG0012	GTP binding
B7G68_RS02805	COG1741	Belongs to the pirin family
B7G68_RS02820	COG0596	Alpha beta hydrolase
B7G68_RS02850	COG1496	oxidoreductase activity
B7G68_RS02890	COG0745	RESPONSE REGULATOR receiver
B7G68_RS02915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B7G68_RS02960	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
B7G68_RS03015	COG0500	methyltransferase
B7G68_RS03040	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B7G68_RS03070	COG1595	DNA-templated transcription, initiation
B7G68_RS03080	COG2951	lytic endotransglycosylase activity
B7G68_RS03185	COG0739	heme binding
B7G68_RS03195	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B7G68_RS03250	COG3706	GGDEF domain
B7G68_RS03255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B7G68_RS03260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B7G68_RS03270	COG0519	Catalyzes the synthesis of GMP from XMP
B7G68_RS03275	COG3655	Transcriptional regulator
B7G68_RS03295	COG1794	racemase activity, acting on amino acids and derivatives
B7G68_RS03300	COG3537	Alpha-1,2-mannosidase
B7G68_RS03305	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B7G68_RS03320	COG1132	(ABC) transporter
B7G68_RS03335	COG0584	glycerophosphoryl diester phosphodiesterase
B7G68_RS03340	COG0483	inositol monophosphate 1-phosphatase activity
B7G68_RS03350	COG0352	thiamine-phosphate diphosphorylase activity
B7G68_RS03370	COG0840	transmembrane signaling receptor activity
B7G68_RS03415	COG0126	phosphoglycerate kinase activity
B7G68_RS03445	COG1692	metallophosphoesterase
B7G68_RS03450	COG1764	response to oxidative stress
B7G68_RS03460	COG1285	pathogenesis
B7G68_RS03475	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B7G68_RS03480	COG0632	four-way junction helicase activity
B7G68_RS03495	COG0824	Thioesterase
B7G68_RS03515	COG0823	Involved in the tonB-independent uptake of proteins
B7G68_RS03520	COG2885	chlorophyll binding
B7G68_RS03530	COG0037	tRNA processing
B7G68_RS03540	COG0784	Response regulator, receiver
B7G68_RS03540	COG4191	Histidine kinase
B7G68_RS03545	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B7G68_RS03555	COG0351	phosphomethylpyrimidine kinase
B7G68_RS03555	COG0352	thiamine-phosphate diphosphorylase activity
B7G68_RS03565	COG0384	phenazine biosynthesis protein PhzF
B7G68_RS03590	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B7G68_RS03595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7G68_RS03630	COG2205	protein histidine kinase activity
B7G68_RS03630	COG0784	Response regulator, receiver
B7G68_RS03655	COG0583	DNA-binding transcription factor activity
B7G68_RS03660	COG1086	Polysaccharide biosynthesis protein
B7G68_RS03665	COG0303	'Molybdopterin
B7G68_RS03735	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B7G68_RS03755	COG0537	adenosine 5'-monophosphoramidase activity
B7G68_RS03775	COG3920	Histidine kinase
B7G68_RS03795	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B7G68_RS03810	COG0840	transmembrane signaling receptor activity
B7G68_RS03825	COG0583	DNA-binding transcription factor activity
B7G68_RS03835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7G68_RS03865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B7G68_RS03880	COG0753	catalase activity
B7G68_RS03905	COG1538	Outer membrane efflux protein
B7G68_RS03950	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7G68_RS03950	COG1024	Enoyl-CoA hydratase
B7G68_RS03970	COG0598	Magnesium transport protein CorA
B7G68_RS03985	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS03995	COG1741	Belongs to the pirin family
B7G68_RS04000	COG0477	Major facilitator Superfamily
B7G68_RS04005	COG1522	sequence-specific DNA binding
B7G68_RS04015	COG2311	Membrane
B7G68_RS04020	COG0579	oxidoreductase
B7G68_RS04050	COG0584	glycerophosphoryl diester phosphodiesterase
B7G68_RS04060	COG3920	Histidine kinase
B7G68_RS04060	COG2202	Pas domain
B7G68_RS04080	COG1396	sequence-specific DNA binding
B7G68_RS04090	COG4771	TonB-dependent receptor
B7G68_RS04100	COG0602	queuosine metabolic process
B7G68_RS04115	COG2205	protein histidine kinase activity
B7G68_RS04115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7G68_RS04145	COG1846	Transcriptional regulator
B7G68_RS04150	COG2200	EAL domain
B7G68_RS04155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7G68_RS04165	COG1012	belongs to the aldehyde dehydrogenase family
B7G68_RS04170	COG1012	belongs to the aldehyde dehydrogenase family
B7G68_RS04175	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B7G68_RS04180	COG0174	glutamine synthetase
B7G68_RS04190	COG1176	ABC-type spermidine putrescine transport system, permease component I
B7G68_RS04195	COG1177	transmembrane transport
B7G68_RS04200	COG3842	ATPase activity
B7G68_RS04205	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B7G68_RS04215	COG0174	glutamine synthetase
B7G68_RS04220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7G68_RS04225	COG0457	Tetratricopeptide repeat
B7G68_RS04235	COG0531	amino acid
B7G68_RS04240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B7G68_RS04245	COG4772	TonB-dependent receptor
B7G68_RS04260	COG4638	Rieske (2fe-2S)
B7G68_RS04285	COG1309	transcriptional regulator
B7G68_RS04300	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS04305	COG0583	DNA-binding transcription factor activity
B7G68_RS04310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7G68_RS04320	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7G68_RS04325	COG1595	DNA-templated transcription, initiation
B7G68_RS04340	COG4948	Mandelate Racemase Muconate Lactonizing
B7G68_RS04350	COG0183	Belongs to the thiolase family
B7G68_RS04365	COG1760	l-serine dehydratase
B7G68_RS04375	COG3616	Alanine racemase, N-terminal domain
B7G68_RS04395	COG0784	Response regulator, receiver
B7G68_RS04395	COG2198	Histidine kinase
B7G68_RS04395	COG2205	protein histidine kinase activity
B7G68_RS04415	COG0596	Alpha beta hydrolase
B7G68_RS04435	COG1950	PFAM Membrane protein of
B7G68_RS04440	COG3300	MHYT domain
B7G68_RS04440	COG5001	Diguanylate cyclase
B7G68_RS04450	COG0596	Alpha beta hydrolase
B7G68_RS04480	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B7G68_RS04515	COG0513	Belongs to the DEAD box helicase family
B7G68_RS04530	COG2226	methyltransferase
B7G68_RS04535	COG1040	competence protein
B7G68_RS04540	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B7G68_RS04545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7G68_RS04560	COG1501	Belongs to the glycosyl hydrolase 31 family
B7G68_RS04590	COG0527	aspartate kinase activity
B7G68_RS04630	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B7G68_RS04680	COG1187	pseudouridine synthase activity
B7G68_RS04685	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B7G68_RS04690	COG5001	Diguanylate cyclase
B7G68_RS04695	COG4774	siderophore transport
B7G68_RS04705	COG0784	Response regulator, receiver
B7G68_RS04705	COG4191	Histidine kinase
B7G68_RS04730	COG2089	acid synthase
B7G68_RS04745	COG0640	Transcriptional regulator
B7G68_RS04750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7G68_RS04765	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
B7G68_RS04780	COG0840	transmembrane signaling receptor activity
B7G68_RS04790	COG3660	Nucleoside-diphosphate-sugar epimerase
B7G68_RS04810	COG0572	uridine kinase
B7G68_RS04815	COG2202	Pas domain
B7G68_RS04815	COG3920	Histidine kinase
B7G68_RS04820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B7G68_RS04830	COG1278	Cold shock
B7G68_RS04850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B7G68_RS04870	COG0463	Glycosyl transferase, family 2
B7G68_RS04895	COG2205	protein histidine kinase activity
B7G68_RS04900	COG0322	excinuclease ABC activity
B7G68_RS04905	COG3668	Plasmid stabilization system
B7G68_RS04950	COG0505	Belongs to the CarA family
B7G68_RS04955	COG3813	Protein conserved in bacteria
B7G68_RS04975	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B7G68_RS04990	COG2186	Transcriptional regulator
B7G68_RS04995	COG4948	Mandelate Racemase Muconate Lactonizing
B7G68_RS05000	COG3661	Belongs to the glycosyl hydrolase 67 family
B7G68_RS05005	COG1473	amidohydrolase
B7G68_RS05015	COG3507	Belongs to the glycosyl hydrolase 43 family
B7G68_RS05020	COG0545	Peptidyl-prolyl cis-trans isomerase
B7G68_RS05030	COG1231	oxidoreductase activity
B7G68_RS05050	COG2852	Protein conserved in bacteria
B7G68_RS05055	COG4695	Portal protein
B7G68_RS05140	COG0484	heat shock protein binding
B7G68_RS05170	COG4235	cytochrome complex assembly
B7G68_RS05180	COG1138	Cytochrome C-type biogenesis protein
B7G68_RS05190	COG3088	subunit of a heme lyase
B7G68_RS05200	COG0745	RESPONSE REGULATOR receiver
B7G68_RS05220	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B7G68_RS05230	COG1595	DNA-templated transcription, initiation
B7G68_RS05245	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B7G68_RS05250	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
B7G68_RS05260	COG2003	Belongs to the UPF0758 family
B7G68_RS05265	COG0024	Methionine aminopeptidase
B7G68_RS05280	COG1546	Belongs to the CinA family
B7G68_RS05280	COG1058	Belongs to the CinA family
B7G68_RS05285	COG1396	sequence-specific DNA binding
B7G68_RS05300	COG1228	amidohydrolase
B7G68_RS05310	COG0784	Response regulator, receiver
B7G68_RS05310	COG2205	protein histidine kinase activity
B7G68_RS05315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B7G68_RS05320	COG2011	ABC-type metal ion transport system permease component
B7G68_RS05380	COG0778	Nitroreductase
B7G68_RS05395	COG1045	serine acetyltransferase
B7G68_RS05430	COG1297	OPT oligopeptide transporter protein
B7G68_RS05440	COG1702	phosphate starvation-inducible protein PhoH
B7G68_RS05460	COG0612	Peptidase, M16
B7G68_RS05470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7G68_RS05475	COG1116	anion transmembrane transporter activity
B7G68_RS05475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7G68_RS05490	COG0488	(ABC) transporter
B7G68_RS05505	COG0517	IMP dehydrogenase activity
B7G68_RS05505	COG0516	GMP reductase activity
B7G68_RS05550	COG1278	Cold shock
B7G68_RS05560	COG2351	hydroxyisourate hydrolase activity
B7G68_RS05570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7G68_RS05580	COG0402	S-adenosylhomocysteine deaminase activity
B7G68_RS05610	COG2353	YceI-like domain
B7G68_RS05635	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B7G68_RS05655	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B7G68_RS05660	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B7G68_RS05680	COG0625	glutathione transferase activity
B7G68_RS05690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7G68_RS05710	COG0488	(ABC) transporter
B7G68_RS05730	COG3951	Flagellar rod assembly protein muramidase FlgJ
B7G68_RS05735	COG1706	bacterial-type flagellum-dependent cell motility
B7G68_RS05760	COG0784	Response regulator, receiver
B7G68_RS05765	COG1024	Enoyl-CoA hydratase
B7G68_RS05790	COG0697	spore germination
B7G68_RS05795	COG3023	N-Acetylmuramoyl-L-alanine amidase
B7G68_RS05830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B7G68_RS05835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B7G68_RS05915	COG1181	Belongs to the D-alanine--D-alanine ligase family
B7G68_RS05925	COG0849	cell division
B7G68_RS05935	COG0523	cobalamin synthesis protein
B7G68_RS05960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B7G68_RS05995	COG2010	Cytochrome c
B7G68_RS06025	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B7G68_RS06055	COG2200	EAL domain
B7G68_RS06070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B7G68_RS06105	COG0538	isocitrate dehydrogenase activity
B7G68_RS06110	COG0784	Response regulator, receiver
B7G68_RS06110	COG2198	Histidine kinase
B7G68_RS06110	COG2205	protein histidine kinase activity
B7G68_RS06135	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B7G68_RS06140	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
B7G68_RS06185	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B7G68_RS06195	COG0271	Belongs to the BolA IbaG family
B7G68_RS06200	COG2234	aminopeptidase activity
B7G68_RS06205	COG5002	protein histidine kinase activity
B7G68_RS06205	COG2198	Histidine kinase
B7G68_RS06205	COG0784	Response regulator, receiver
B7G68_RS06210	COG2202	Pas domain
B7G68_RS06210	COG3920	Histidine kinase
B7G68_RS06220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7G68_RS06235	COG0047	phosphoribosylformylglycinamidine synthase activity
B7G68_RS06245	COG1773	rubredoxin
B7G68_RS06260	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7G68_RS06265	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B7G68_RS06290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B7G68_RS06295	COG2814	Major facilitator Superfamily
B7G68_RS06300	COG2814	Major facilitator Superfamily
B7G68_RS06340	COG1823	symporter activity
B7G68_RS06365	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS06395	COG0583	DNA-binding transcription factor activity
B7G68_RS06400	COG1648	precorrin-2 dehydrogenase activity
B7G68_RS06400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7G68_RS06410	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7G68_RS06420	COG0175	sulfate reduction
B7G68_RS06445	COG0625	glutathione transferase activity
B7G68_RS06465	COG2202	Pas domain
B7G68_RS06465	COG2205	protein histidine kinase activity
B7G68_RS06470	COG0308	aminopeptidase N
B7G68_RS06485	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS06495	COG0154	amidase activity
B7G68_RS06535	COG0681	Belongs to the peptidase S26 family
B7G68_RS06545	COG0488	(ABC) transporter
B7G68_RS06560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B7G68_RS06590	COG1410	methionine synthase
B7G68_RS06590	COG0646	methionine synthase
B7G68_RS06630	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS06635	COG1902	pentaerythritol trinitrate reductase activity
B7G68_RS06655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B7G68_RS06665	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B7G68_RS06690	COG0640	Transcriptional regulator
B7G68_RS06720	COG0142	geranyltranstransferase activity
B7G68_RS06730	COG0114	fumarate hydratase activity
B7G68_RS06745	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7G68_RS06775	COG2207	Transcriptional regulator
B7G68_RS06795	COG0028	Belongs to the TPP enzyme family
B7G68_RS06805	COG1546	Belongs to the CinA family
B7G68_RS06805	COG1058	Belongs to the CinA family
B7G68_RS06825	COG0560	Phosphoserine phosphatase
B7G68_RS06830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7G68_RS06840	COG0489	protein tyrosine kinase activity
B7G68_RS06850	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS06865	COG1566	PFAM secretion protein HlyD family protein
B7G68_RS06870	COG0577	efflux transmembrane transporter activity
B7G68_RS06870	COG1136	(ABC) transporter
B7G68_RS06885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7G68_RS06910	COG1573	uracil-dna glycosylase
B7G68_RS06930	COG0477	Major facilitator Superfamily
B7G68_RS06975	COG1733	regulation of RNA biosynthetic process
B7G68_RS06995	COG0142	geranyltranstransferase activity
B7G68_RS07010	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
B7G68_RS07015	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
B7G68_RS07020	COG4786	Flagellar basal body rod
B7G68_RS07025	COG4786	Flagellar basal body rod
B7G68_RS07055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B7G68_RS07060	COG0363	glucosamine-6-phosphate deaminase activity
B7G68_RS07065	COG0129	dihydroxy-acid dehydratase activity
B7G68_RS07090	COG0469	pyruvate kinase activity
B7G68_RS07110	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS07115	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B7G68_RS07115	COG0392	lysyltransferase activity
B7G68_RS07145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7G68_RS07145	COG1199	ATP-dependent helicase activity
B7G68_RS07165	COG2515	1-aminocyclopropane-1-carboxylate deaminase
B7G68_RS07180	COG2321	neutral zinc metallopeptidase
B7G68_RS07235	COG0346	lactoylglutathione lyase activity
B7G68_RS07240	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS07245	COG0534	Mate efflux family protein
B7G68_RS07265	COG2130	NADP-dependent
B7G68_RS07270	COG0673	inositol 2-dehydrogenase activity
B7G68_RS07285	COG0316	Belongs to the HesB IscA family
B7G68_RS07300	COG1472	Belongs to the glycosyl hydrolase 3 family
B7G68_RS07305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B7G68_RS07310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B7G68_RS07330	COG0805	protein transport
B7G68_RS07365	COG1862	Preprotein translocase
B7G68_RS07375	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7G68_RS07380	COG3737	Protein of unknown function (DUF498/DUF598)
B7G68_RS07395	COG1506	peptidase
B7G68_RS07395	COG0823	Involved in the tonB-independent uptake of proteins
B7G68_RS07400	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
B7G68_RS07405	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7G68_RS07410	COG0497	DNA recombination
B7G68_RS07425	COG0006	proline dipeptidase activity
B7G68_RS07435	COG2264	protein methyltransferase activity
B7G68_RS07450	COG0210	DNA helicase
B7G68_RS07480	COG0625	glutathione transferase activity
B7G68_RS07505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7G68_RS07540	COG0768	penicillin binding
B7G68_RS07545	COG0772	Belongs to the SEDS family
B7G68_RS07560	COG2267	carboxylic ester hydrolase activity
B7G68_RS07565	COG2814	Major facilitator Superfamily
B7G68_RS07570	COG2363	Small membrane protein
B7G68_RS07590	COG0861	Integral membrane protein TerC family
B7G68_RS07600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7G68_RS07615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B7G68_RS07640	COG0492	ferredoxin-NADP+ reductase activity
B7G68_RS07645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B7G68_RS07650	COG0243	molybdopterin cofactor binding
B7G68_RS07670	COG0051	transcription antitermination factor activity, RNA binding
B7G68_RS07675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B7G68_RS07700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B7G68_RS07740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B7G68_RS07775	COG0201	protein transport
B7G68_RS07855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7G68_RS07860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B7G68_RS07865	COG0564	pseudouridine synthase activity
B7G68_RS07905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7G68_RS07925	COG2814	Major facilitator Superfamily
B7G68_RS07935	COG0175	sulfate reduction
B7G68_RS07950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7G68_RS07955	COG0246	Mannitol dehydrogenase
B7G68_RS07960	COG2721	sulfolactate sulfo-lyase activity
B7G68_RS07965	COG1609	Transcriptional regulator
B7G68_RS07980	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS07985	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B7G68_RS08000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7G68_RS08045	COG0475	glutathione-regulated potassium exporter activity
B7G68_RS08065	COG2133	pyrroloquinoline quinone binding
B7G68_RS08070	COG0673	inositol 2-dehydrogenase activity
B7G68_RS08075	COG2271	Major facilitator Superfamily
B7G68_RS08085	COG3682	Transcriptional regulator
B7G68_RS08100	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
B7G68_RS08105	COG1877	trehalose-phosphatase activity
B7G68_RS08120	COG2989	Protein conserved in bacteria
B7G68_RS08125	COG3108	Peptidase M15
B7G68_RS08140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7G68_RS08160	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
B7G68_RS08165	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B7G68_RS08170	COG1999	signal sequence binding
B7G68_RS08190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7G68_RS08210	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B7G68_RS08215	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS08220	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS08250	COG5265	(ABC) transporter
B7G68_RS08255	COG0346	lactoylglutathione lyase activity
B7G68_RS08265	COG0625	glutathione transferase activity
B7G68_RS08285	COG0438	transferase activity, transferring glycosyl groups
B7G68_RS08310	COG0525	valine-tRNA ligase activity
B7G68_RS08315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7G68_RS08325	COG0318	PFAM AMP-dependent synthetase and ligase
B7G68_RS08340	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B7G68_RS08350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B7G68_RS08360	COG3795	YCII-related domain
B7G68_RS08365	COG4941	Belongs to the sigma-70 factor family
B7G68_RS08380	COG0741	lytic transglycosylase activity
B7G68_RS08385	COG1573	uracil-dna glycosylase
B7G68_RS08405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B7G68_RS08415	COG0004	ammonium transporteR
B7G68_RS08420	COG0347	Belongs to the P(II) protein family
B7G68_RS08430	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
B7G68_RS08440	COG0751	glycine-tRNA ligase activity
B7G68_RS08475	COG0113	porphobilinogen synthase activity
B7G68_RS08480	COG2072	flavoprotein involved in K transport
B7G68_RS08490	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS08495	COG0406	alpha-ribazole phosphatase activity
B7G68_RS08500	COG1024	Enoyl-CoA hydratase
B7G68_RS08515	COG0156	8-amino-7-oxononanoate synthase activity
B7G68_RS08520	COG4957	zinc ion binding
B7G68_RS08525	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B7G68_RS08535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B7G68_RS08545	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B7G68_RS08555	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
B7G68_RS08560	COG2201	protein-glutamate methylesterase activity
B7G68_RS08580	COG0416	fatty acid biosynthetic process
B7G68_RS08585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7G68_RS08590	COG0776	regulation of translation
B7G68_RS08620	COG1785	Belongs to the alkaline phosphatase family
B7G68_RS08630	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B7G68_RS08645	COG3243	poly(R)-hydroxyalkanoic acid synthase
B7G68_RS08655	COG0436	Aminotransferase
B7G68_RS08665	COG1494	fructose-1,6-bisphosphatase
B7G68_RS08670	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
B7G68_RS08675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B7G68_RS08675	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B7G68_RS08690	COG1278	Cold shock
B7G68_RS08855	COG1012	belongs to the aldehyde dehydrogenase family
B7G68_RS08870	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS08875	COG4771	TonB-dependent receptor
B7G68_RS08885	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS08890	COG4774	siderophore transport
B7G68_RS08895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7G68_RS08935	COG0196	riboflavin kinase activity
B7G68_RS08955	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7G68_RS09025	COG0183	Belongs to the thiolase family
B7G68_RS09055	COG0745	RESPONSE REGULATOR receiver
B7G68_RS09060	COG2205	protein histidine kinase activity
B7G68_RS09070	COG3250	beta-galactosidase activity
B7G68_RS09075	COG1304	FMN binding
B7G68_RS09085	COG1414	Transcriptional regulator
B7G68_RS09090	COG4948	Mandelate Racemase Muconate Lactonizing
B7G68_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS09105	COG3618	amidohydrolase
B7G68_RS09160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7G68_RS09170	COG2755	lipolytic protein G-D-S-L family
B7G68_RS09170	COG0657	acetylesterase activity
B7G68_RS09185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7G68_RS09190	COG1335	isochorismatase
B7G68_RS09200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7G68_RS09205	COG2175	clavaminate synthase activity
B7G68_RS09210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7G68_RS09220	COG0300	oxidoreductase activity
B7G68_RS09225	COG2175	clavaminate synthase activity
B7G68_RS09235	COG3384	dioxygenase
B7G68_RS09270	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7G68_RS09270	COG2010	Cytochrome c
B7G68_RS09290	COG0789	Transcriptional regulator
B7G68_RS09320	COG4771	TonB-dependent receptor
B7G68_RS09325	COG3712	iron ion homeostasis
B7G68_RS09365	COG4948	Mandelate Racemase Muconate Lactonizing
B7G68_RS09370	COG3250	beta-galactosidase activity
B7G68_RS09385	COG3254	rhamnose metabolic process
B7G68_RS09390	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7G68_RS09395	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS09400	COG2721	sulfolactate sulfo-lyase activity
B7G68_RS09405	COG2721	sulfolactate sulfo-lyase activity
B7G68_RS09420	COG1063	alcohol dehydrogenase
B7G68_RS09425	COG0738	Major facilitator superfamily
B7G68_RS09485	COG4946	Tricorn protease homolog
B7G68_RS09485	COG0793	Belongs to the peptidase S41A family
B7G68_RS09495	COG1136	(ABC) transporter
B7G68_RS09515	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B7G68_RS09525	COG2205	protein histidine kinase activity
B7G68_RS09530	COG0745	RESPONSE REGULATOR receiver
B7G68_RS09540	COG2186	Transcriptional regulator
B7G68_RS09545	COG3265	gluconokinase activity
B7G68_RS09565	COG3273	potassium ion transport
B7G68_RS09565	COG0471	metal ion transport
B7G68_RS09600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7G68_RS09605	COG0463	Glycosyl transferase, family 2
B7G68_RS09605	COG1216	Glycosyl transferase, family 2
B7G68_RS09615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B7G68_RS09620	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B7G68_RS09625	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B7G68_RS09665	COG3278	Belongs to the heme-copper respiratory oxidase family
B7G68_RS09680	COG2010	Cytochrome c
B7G68_RS09695	COG2217	Heavy metal translocating P-type atpase
B7G68_RS09705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7G68_RS09710	COG3047	cAMP biosynthetic process
B7G68_RS09715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7G68_RS09720	COG1335	isochorismatase
B7G68_RS09740	COG0129	dihydroxy-acid dehydratase activity
B7G68_RS09755	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
B7G68_RS09760	COG1902	pentaerythritol trinitrate reductase activity
B7G68_RS09775	COG0626	cystathionine gamma-synthase activity
B7G68_RS09780	COG2897	thiosulfate sulfurtransferase activity
B7G68_RS09785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7G68_RS09790	COG3046	protein related to deoxyribodipyrimidine photolyase
B7G68_RS09795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B7G68_RS09800	COG0415	Belongs to the DNA photolyase family
B7G68_RS09820	COG0183	Belongs to the thiolase family
B7G68_RS09840	COG2354	Protein conserved in bacteria
B7G68_RS09855	COG1126	abc transporter atp-binding protein
B7G68_RS09860	COG0765	amino acid transport
B7G68_RS09865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7G68_RS09900	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
B7G68_RS09920	COG3604	Transcriptional regulator
B7G68_RS09930	COG0457	Tetratricopeptide repeat
B7G68_RS09930	COG0859	PFAM glycosyl transferase family 9
B7G68_RS09940	COG5442	Flagellar protein FlaF
B7G68_RS09945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B7G68_RS09950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B7G68_RS09970	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7G68_RS09985	COG0629	single-stranded DNA binding
B7G68_RS09995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7G68_RS09995	COG0574	Belongs to the PEP-utilizing enzyme family
B7G68_RS10000	COG2226	methyltransferase
B7G68_RS10010	COG1741	Belongs to the pirin family
B7G68_RS10025	COG0443	Heat shock 70 kDa protein
B7G68_RS10030	COG2081	HI0933 family
B7G68_RS10075	COG1024	Enoyl-CoA hydratase
B7G68_RS10090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B7G68_RS10095	COG0022	dehydrogenase e1 component
B7G68_RS10095	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7G68_RS10100	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7G68_RS10105	COG0386	Belongs to the glutathione peroxidase family
B7G68_RS10110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7G68_RS10120	COG2259	Doxx family
B7G68_RS10125	COG0318	PFAM AMP-dependent synthetase and ligase
B7G68_RS10125	COG0204	Acyl-transferase
B7G68_RS10135	COG2867	negative regulation of translational initiation
B7G68_RS10145	COG1058	Belongs to the CinA family
B7G68_RS10145	COG1546	Belongs to the CinA family
B7G68_RS10155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7G68_RS10160	COG3852	Histidine kinase
B7G68_RS10165	COG2204	response regulator
B7G68_RS10170	COG5000	phosphorelay sensor kinase activity
B7G68_RS10175	COG2204	response regulator
B7G68_RS10180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7G68_RS10190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B7G68_RS10195	COG3956	TIGRFAM MazG family protein
B7G68_RS10215	COG4206	TonB-dependent receptor
B7G68_RS10235	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B7G68_RS10240	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
B7G68_RS10245	COG1492	cobalamin metabolic process
B7G68_RS10250	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B7G68_RS10255	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B7G68_RS10265	COG0657	acetylesterase activity
B7G68_RS10265	COG2755	lipolytic protein G-D-S-L family
B7G68_RS10275	COG1472	Belongs to the glycosyl hydrolase 3 family
B7G68_RS10315	COG0129	dihydroxy-acid dehydratase activity
B7G68_RS10325	COG2186	Transcriptional regulator
B7G68_RS10345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7G68_RS10355	COG0437	4 iron, 4 sulfur cluster binding
B7G68_RS10380	COG0583	DNA-binding transcription factor activity
B7G68_RS10385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7G68_RS10390	COG1116	anion transmembrane transporter activity
B7G68_RS10395	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS10400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7G68_RS10430	COG0625	glutathione transferase activity
B7G68_RS10435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7G68_RS10475	COG0583	DNA-binding transcription factor activity
B7G68_RS10485	COG3321	synthase
B7G68_RS10485	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS10485	COG0604	alcohol dehydrogenase
B7G68_RS10495	COG4124	Belongs to the glycosyl hydrolase 26 family
B7G68_RS10495	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B7G68_RS10525	COG1648	precorrin-2 dehydrogenase activity
B7G68_RS10525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7G68_RS10530	COG0243	molybdopterin cofactor binding
B7G68_RS10540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7G68_RS10545	COG2223	nitrite transmembrane transporter activity
B7G68_RS10560	COG1116	anion transmembrane transporter activity
B7G68_RS10565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7G68_RS10570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7G68_RS10580	COG3279	Response regulator of the LytR AlgR family
B7G68_RS10585	COG3275	phosphorelay sensor kinase activity
B7G68_RS10595	COG3263	regulation of cellular component size
B7G68_RS10605	COG4977	sequence-specific DNA binding
B7G68_RS10630	COG1309	transcriptional regulator
B7G68_RS10635	COG1335	isochorismatase
B7G68_RS10640	COG0251	oxidation-reduction process
B7G68_RS10645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7G68_RS10650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7G68_RS10675	COG2080	2 iron, 2 sulfur cluster binding
B7G68_RS10680	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B7G68_RS10685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7G68_RS10690	COG1764	response to oxidative stress
B7G68_RS10700	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS10710	COG2843	Capsule synthesis protein
B7G68_RS10730	COG2197	response regulator
B7G68_RS10745	COG1335	isochorismatase
B7G68_RS10790	COG3474	cytochrome
B7G68_RS10800	COG0673	inositol 2-dehydrogenase activity
B7G68_RS10810	COG2211	Major facilitator Superfamily
B7G68_RS10815	COG1609	Transcriptional regulator
B7G68_RS10825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7G68_RS10830	COG0577	efflux transmembrane transporter activity
B7G68_RS10830	COG1136	(ABC) transporter
B7G68_RS10835	COG1136	(ABC) transporter
B7G68_RS10850	COG0084	hydrolase, TatD family'
B7G68_RS10860	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B7G68_RS10875	COG2813	Specifically methylates the guanine in position
B7G68_RS10880	COG1187	pseudouridine synthase activity
B7G68_RS10895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7G68_RS10920	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B7G68_RS10955	COG1012	belongs to the aldehyde dehydrogenase family
B7G68_RS10960	COG3706	GGDEF domain
B7G68_RS10965	COG1024	Enoyl-CoA hydratase
B7G68_RS10985	COG0316	Belongs to the HesB IscA family
B7G68_RS10990	COG2151	metal-sulfur cluster biosynthetic enzyme
B7G68_RS10995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7G68_RS11000	COG0719	Fe-S assembly protein
B7G68_RS11005	COG0396	ATPase activity
B7G68_RS11010	COG0719	Fe-S assembly protein
B7G68_RS11020	COG1959	2 iron, 2 sulfur cluster binding
B7G68_RS11025	COG2945	thiolester hydrolase activity
B7G68_RS11030	COG1252	NADH dehydrogenase
B7G68_RS11040	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B7G68_RS11055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B7G68_RS11060	COG0739	heme binding
B7G68_RS11070	COG0346	lactoylglutathione lyase activity
B7G68_RS11085	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B7G68_RS11090	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7G68_RS11100	COG1530	ribonuclease E activity
B7G68_RS11105	COG0501	Belongs to the peptidase M48B family
B7G68_RS11130	COG0511	ligase activity, forming carbon-carbon bonds
B7G68_RS11135	COG0439	Biotin carboxylase
B7G68_RS11155	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7G68_RS11165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B7G68_RS11170	COG0149	triose-phosphate isomerase activity
B7G68_RS11175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7G68_RS11180	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7G68_RS11205	COG2226	methyltransferase
B7G68_RS11210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B7G68_RS11215	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B7G68_RS11220	COG2333	competence protein COMEC
B7G68_RS11220	COG0658	competence protein
B7G68_RS11225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B7G68_RS11230	COG0372	Belongs to the citrate synthase family
B7G68_RS11245	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B7G68_RS11250	COG3494	Protein of unknown function (DUF1009)
B7G68_RS11275	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7G68_RS11280	COG0750	zinc metalloprotease
B7G68_RS11290	COG0575	Belongs to the CDS family
B7G68_RS11295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B7G68_RS11305	COG0528	UMP kinase activity
B7G68_RS11330	COG3615	Tellurite resistance protein tehB
B7G68_RS11330	COG0500	methyltransferase
B7G68_RS11355	COG1136	(ABC) transporter
B7G68_RS11380	COG0346	lactoylglutathione lyase activity
B7G68_RS11390	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B7G68_RS11400	COG1007	ATP synthesis coupled electron transport
B7G68_RS11425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7G68_RS11440	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B7G68_RS11450	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B7G68_RS11475	COG0649	NAD binding
B7G68_RS11480	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7G68_RS11505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7G68_RS11510	COG0297	glycogen (starch) synthase activity
B7G68_RS11565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B7G68_RS11565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B7G68_RS11570	COG0406	alpha-ribazole phosphatase activity
B7G68_RS11580	COG0347	Belongs to the P(II) protein family
B7G68_RS11585	COG0174	glutamine synthetase
B7G68_RS11600	COG1228	amidohydrolase
B7G68_RS11605	COG1228	amidohydrolase
B7G68_RS11610	COG0187	DNA topoisomerase II activity
B7G68_RS11645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B7G68_RS11665	COG2205	protein histidine kinase activity
B7G68_RS11665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7G68_RS11670	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B7G68_RS11675	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B7G68_RS11680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B7G68_RS11705	COG0488	(ABC) transporter
B7G68_RS11720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7G68_RS11750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B7G68_RS11770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7G68_RS11775	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B7G68_RS11780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B7G68_RS11800	COG0194	GDP metabolic process
B7G68_RS11805	COG1561	YicC-like family, N-terminal region
B7G68_RS11810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B7G68_RS11815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7G68_RS11830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B7G68_RS11860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B7G68_RS11875	COG0305	Participates in initiation and elongation during chromosome replication
B7G68_RS11885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7G68_RS11900	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B7G68_RS11910	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS11920	COG1160	GTP binding
B7G68_RS11945	COG1595	DNA-templated transcription, initiation
B7G68_RS11960	COG1595	DNA-templated transcription, initiation
B7G68_RS11975	COG0546	phosphoglycolate phosphatase activity
B7G68_RS11980	COG1393	Belongs to the ArsC family
B7G68_RS11995	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
B7G68_RS12005	COG1802	Transcriptional regulator
B7G68_RS12025	COG4771	TonB-dependent receptor
B7G68_RS12035	COG1024	Enoyl-CoA hydratase
B7G68_RS12040	COG1012	belongs to the aldehyde dehydrogenase family
B7G68_RS12065	COG0183	Belongs to the thiolase family
B7G68_RS12070	COG3485	protocatechuate 3,4-dioxygenase
B7G68_RS12075	COG3485	protocatechuate 3,4-dioxygenase
B7G68_RS12080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B7G68_RS12085	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7G68_RS12100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7G68_RS12115	COG2843	Capsule synthesis protein
B7G68_RS12125	COG2271	Major facilitator Superfamily
B7G68_RS12135	COG2814	Major facilitator Superfamily
B7G68_RS12145	COG0183	Belongs to the thiolase family
B7G68_RS12150	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS12170	COG4771	TonB-dependent receptor
B7G68_RS12195	COG0835	chemotaxis
B7G68_RS12205	COG1609	Transcriptional regulator
B7G68_RS12220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7G68_RS12280	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS12290	COG0583	DNA-binding transcription factor activity
B7G68_RS12300	COG0798	PFAM Bile acid sodium symporter
B7G68_RS12340	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
B7G68_RS12360	COG4771	TonB-dependent receptor
B7G68_RS12365	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS12385	COG0583	DNA-binding transcription factor activity
B7G68_RS12425	COG1595	DNA-templated transcription, initiation
B7G68_RS12465	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS12470	COG0583	DNA-binding transcription factor activity
B7G68_RS12485	COG2207	Transcriptional regulator
B7G68_RS12500	COG3713	MltA-interacting MipA family protein
B7G68_RS12505	COG2272	Belongs to the type-B carboxylesterase lipase family
B7G68_RS12510	COG1472	Belongs to the glycosyl hydrolase 3 family
B7G68_RS12520	COG4771	TonB-dependent receptor
B7G68_RS12525	COG1609	Transcriptional regulator
B7G68_RS12535	COG0745	RESPONSE REGULATOR receiver
B7G68_RS12540	COG5002	protein histidine kinase activity
B7G68_RS12550	COG2853	Lipoprotein
B7G68_RS12555	COG0784	Response regulator, receiver
B7G68_RS12555	COG2205	protein histidine kinase activity
B7G68_RS12605	COG0798	PFAM Bile acid sodium symporter
B7G68_RS12630	COG0431	NADPH-dependent FMN reductase
B7G68_RS12645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7G68_RS12655	COG1126	abc transporter atp-binding protein
B7G68_RS12660	COG0765	amino acid transport
B7G68_RS12665	COG4597	amino acid ABC transporter
B7G68_RS12670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7G68_RS12690	COG1228	amidohydrolase
B7G68_RS12695	COG1522	sequence-specific DNA binding
B7G68_RS12750	COG2176	DNA-directed DNA polymerase activity
B7G68_RS12775	COG3504	Conjugal transfer protein
B7G68_RS12800	COG3451	type IV secretory pathway VirB4
B7G68_RS12815	COG4962	Type ii secretion system protein e
B7G68_RS12905	COG2132	Multicopper oxidase
B7G68_RS12940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7G68_RS12950	COG0183	Belongs to the thiolase family
B7G68_RS12955	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS12960	COG0318	PFAM AMP-dependent synthetase and ligase
B7G68_RS12970	COG4771	TonB-dependent receptor
B7G68_RS12990	COG1733	regulation of RNA biosynthetic process
B7G68_RS12995	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
B7G68_RS13000	COG0583	DNA-binding transcription factor activity
B7G68_RS13005	COG0702	epimerase
B7G68_RS13035	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B7G68_RS13080	COG0739	heme binding
B7G68_RS13080	COG0741	lytic transglycosylase activity
B7G68_RS13080	COG1196	nuclear chromosome segregation
B7G68_RS13120	COG4771	TonB-dependent receptor
B7G68_RS13165	COG5489	Protein of unknown function (DUF736)
B7G68_RS13190	COG0306	phosphate transporter
B7G68_RS13215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7G68_RS13270	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B7G68_RS13275	COG0248	Ppx GppA phosphatase
B7G68_RS13285	COG3186	Phenylalanine-4-hydroxylase
B7G68_RS13300	COG0456	acetyltransferase
B7G68_RS13300	COG0454	-acetyltransferase
B7G68_RS13305	COG3724	N-succinylarginine dihydrolase activity
B7G68_RS13310	COG1012	belongs to the aldehyde dehydrogenase family
B7G68_RS13335	COG2308	Evidence 4 Homologs of previously reported genes of
B7G68_RS13355	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B7G68_RS13360	COG4208	sulfate ABC transporter
B7G68_RS13385	COG0343	queuine tRNA-ribosyltransferase activity
B7G68_RS13410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B7G68_RS13420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7G68_RS13425	COG2032	superoxide dismutase activity
B7G68_RS13435	COG0697	spore germination
B7G68_RS13440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7G68_RS13455	COG2084	Dehydrogenase
B7G68_RS13460	COG1360	Flagellar Motor Protein
B7G68_RS13480	COG0604	alcohol dehydrogenase
B7G68_RS13480	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS13480	COG3321	synthase
B7G68_RS13505	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7G68_RS13510	COG3540	Alkaline phosphatase
B7G68_RS13520	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B7G68_RS13530	COG1914	H( )-stimulated, divalent metal cation uptake system
B7G68_RS13540	COG0681	Belongs to the peptidase S26 family
B7G68_RS13590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B7G68_RS13600	COG1573	uracil-dna glycosylase
B7G68_RS13610	COG0673	inositol 2-dehydrogenase activity
B7G68_RS13615	COG3386	PFAM SMP-30 Gluconolaconase
B7G68_RS13620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B7G68_RS13630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B7G68_RS13655	COG1012	belongs to the aldehyde dehydrogenase family
B7G68_RS13710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7G68_RS13720	COG0235	Class ii aldolase
B7G68_RS13745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7G68_RS13750	COG0741	lytic transglycosylase activity
B7G68_RS13755	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B7G68_RS13760	COG4139	cobalamin transport
B7G68_RS13780	COG0116	Belongs to the methyltransferase superfamily
B7G68_RS13780	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B7G68_RS13785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7G68_RS13790	COG1643	Atp-dependent helicase
B7G68_RS13795	COG0531	amino acid
B7G68_RS13800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7G68_RS13810	COG2205	protein histidine kinase activity
B7G68_RS13835	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B7G68_RS13855	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B7G68_RS13860	COG3119	arylsulfatase activity
B7G68_RS13875	COG2244	polysaccharide biosynthetic process
B7G68_RS13880	COG0318	PFAM AMP-dependent synthetase and ligase
B7G68_RS13890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7G68_RS13895	COG0156	8-amino-7-oxononanoate synthase activity
B7G68_RS13905	COG1597	lipid kinase activity
B7G68_RS13915	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B7G68_RS13940	COG0456	acetyltransferase
B7G68_RS13950	COG1213	nucleotidyl transferase
B7G68_RS13955	COG0438	transferase activity, transferring glycosyl groups
B7G68_RS13955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B7G68_RS13965	COG2755	lipolytic protein G-D-S-L family
B7G68_RS13990	COG3401	FG-GAP repeat protein
B7G68_RS14005	COG2755	lipolytic protein G-D-S-L family
B7G68_RS14020	COG1414	Transcriptional regulator
B7G68_RS14025	COG4948	Mandelate Racemase Muconate Lactonizing
B7G68_RS14030	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7G68_RS14035	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS14040	COG3618	amidohydrolase
B7G68_RS14045	COG3254	rhamnose metabolic process
B7G68_RS14055	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B7G68_RS14065	COG2197	response regulator
B7G68_RS14070	COG4585	Histidine kinase
B7G68_RS14080	COG1131	(ABC) transporter
B7G68_RS14135	COG1309	transcriptional regulator
B7G68_RS14165	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7G68_RS14195	COG0540	Belongs to the ATCase OTCase family
B7G68_RS14200	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B7G68_RS14215	COG0758	DNA mediated transformation
B7G68_RS14220	COG2226	methyltransferase
B7G68_RS14240	COG1754	DNA topoisomerase type I activity
B7G68_RS14240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7G68_RS14250	COG0557	exoribonuclease II activity
B7G68_RS14260	COG2755	lipolytic protein G-D-S-L family
B7G68_RS14265	COG0436	Aminotransferase
B7G68_RS14275	COG1473	amidohydrolase
B7G68_RS14325	COG1940	carbohydrate kinase activity
B7G68_RS14330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7G68_RS14350	COG0537	adenosine 5'-monophosphoramidase activity
B7G68_RS14385	COG1686	Belongs to the peptidase S11 family
B7G68_RS14390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7G68_RS14400	COG0484	heat shock protein binding
B7G68_RS14410	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B7G68_RS14430	COG1024	Enoyl-CoA hydratase
B7G68_RS14435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7G68_RS14450	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS14460	COG2239	Acts as a magnesium transporter
B7G68_RS14475	COG0321	lipoyl(octanoyl) transferase activity
B7G68_RS14480	COG3152	Membrane
B7G68_RS14485	COG4770	biotin carboxylase activity
B7G68_RS14520	COG0300	oxidoreductase activity
B7G68_RS14535	COG3191	aminopeptidase activity
B7G68_RS14565	COG4771	TonB-dependent receptor
B7G68_RS14575	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B7G68_RS14580	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
B7G68_RS14610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7G68_RS14625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B7G68_RS14650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7G68_RS14655	COG0165	Argininosuccinate lyase
B7G68_RS14665	COG0019	diaminopimelate decarboxylase activity
B7G68_RS14670	COG0840	transmembrane signaling receptor activity
B7G68_RS14675	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B7G68_RS14685	COG2884	Cell division ATP-binding protein ftsE
B7G68_RS14720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B7G68_RS14725	COG0287	Prephenate dehydrogenase
B7G68_RS14740	COG2198	Histidine kinase
B7G68_RS14740	COG0784	Response regulator, receiver
B7G68_RS14740	COG5002	protein histidine kinase activity
B7G68_RS14795	COG0717	Belongs to the dCTP deaminase family
B7G68_RS14805	COG2967	ApaG domain
B7G68_RS14815	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B7G68_RS14820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7G68_RS14840	COG0842	Transport permease protein
B7G68_RS14905	COG0071	Belongs to the small heat shock protein (HSP20) family
B7G68_RS14930	COG0517	IMP dehydrogenase activity
B7G68_RS14930	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B7G68_RS14940	COG0456	acetyltransferase
B7G68_RS14945	COG1228	amidohydrolase
B7G68_RS14985	COG1392	Phosphate transport regulator
B7G68_RS14990	COG0306	phosphate transporter
B7G68_RS15000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B7G68_RS15020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7G68_RS15025	COG1956	GAF domain-containing protein
B7G68_RS15035	COG0840	transmembrane signaling receptor activity
B7G68_RS15050	COG1609	Transcriptional regulator
B7G68_RS15055	COG0366	Alpha amylase catalytic
B7G68_RS15075	COG0688	phosphatidylethanolamine metabolic process
B7G68_RS15100	COG0318	PFAM AMP-dependent synthetase and ligase
B7G68_RS15110	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
B7G68_RS15135	COG0546	phosphoglycolate phosphatase activity
B7G68_RS15215	COG0582	viral genome integration into host DNA
B7G68_RS15220	COG0776	regulation of translation
B7G68_RS15285	COG0235	Class ii aldolase
B7G68_RS15300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7G68_RS15305	COG0583	DNA-binding transcription factor activity
B7G68_RS15315	COG0473	3-isopropylmalate dehydrogenase activity
B7G68_RS15320	COG2851	Citrate transporter
B7G68_RS15350	COG2853	Lipoprotein
B7G68_RS15355	COG0156	8-amino-7-oxononanoate synthase activity
B7G68_RS15380	COG2853	Lipoprotein
B7G68_RS15405	COG2226	methyltransferase
B7G68_RS15410	COG0477	Major facilitator Superfamily
B7G68_RS15415	COG1959	2 iron, 2 sulfur cluster binding
B7G68_RS15425	COG0835	chemotaxis
B7G68_RS15450	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B7G68_RS15490	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS15495	COG0235	Class ii aldolase
B7G68_RS15500	COG4774	siderophore transport
B7G68_RS15525	COG0633	Ferredoxin
B7G68_RS15530	COG0346	lactoylglutathione lyase activity
B7G68_RS15545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7G68_RS15560	COG3794	PFAM blue (type 1) copper domain protein
B7G68_RS15565	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7G68_RS15585	COG4566	intracellular signal transduction
B7G68_RS15590	COG4191	Histidine kinase
B7G68_RS15600	COG0745	RESPONSE REGULATOR receiver
B7G68_RS15620	COG2267	carboxylic ester hydrolase activity
B7G68_RS15665	COG0671	phosphoesterase, PA-phosphatase related
B7G68_RS15675	COG4977	sequence-specific DNA binding
B7G68_RS15680	COG0347	Belongs to the P(II) protein family
B7G68_RS15685	COG2095	MarC family integral membrane protein
B7G68_RS15695	COG1755	Isoprenylcysteine carboxyl methyltransferase
B7G68_RS15700	COG0456	acetyltransferase
B7G68_RS15725	COG1858	cytochrome C peroxidase
B7G68_RS15740	COG2814	Major facilitator Superfamily
B7G68_RS15750	COG1024	Enoyl-CoA hydratase
B7G68_RS15755	COG1113	amino acid transport
B7G68_RS15775	COG2274	protein secretion by the type I secretion system
B7G68_RS15815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B7G68_RS15840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7G68_RS15850	COG1609	Transcriptional regulator
B7G68_RS15855	COG0840	transmembrane signaling receptor activity
B7G68_RS15860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B7G68_RS15865	COG1127	ABC transporter
B7G68_RS15890	COG2205	protein histidine kinase activity
B7G68_RS15890	COG0784	Response regulator, receiver
B7G68_RS15915	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B7G68_RS15915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7G68_RS15920	COG1396	sequence-specific DNA binding
B7G68_RS15930	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B7G68_RS15950	COG0776	regulation of translation
B7G68_RS15970	COG0784	Response regulator, receiver
B7G68_RS15970	COG4191	Histidine kinase
B7G68_RS15990	COG0848	biopolymer transport protein
B7G68_RS16010	COG1530	ribonuclease E activity
B7G68_RS16015	COG0424	maF-like protein
B7G68_RS16020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B7G68_RS16025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7G68_RS16035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B7G68_RS16040	COG1953	Uracil, thiamine, allantoin
B7G68_RS16090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7G68_RS16090	COG1263	PTS System
B7G68_RS16095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7G68_RS16095	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7G68_RS16100	COG2188	Transcriptional regulator
B7G68_RS16105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7G68_RS16110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B7G68_RS16115	COG3537	Alpha-1,2-mannosidase
B7G68_RS16130	COG1566	PFAM secretion protein HlyD family protein
B7G68_RS16140	COG1289	transmembrane transporter activity
B7G68_RS16155	COG1446	asparaginase
B7G68_RS16165	COG0754	glutathionylspermidine amidase activity
B7G68_RS16175	COG3789	protein conserved in bacteria
B7G68_RS16190	COG5463	Belongs to the UPF0441 family
B7G68_RS16210	COG2119	membrane
B7G68_RS16240	COG1703	isobutyryl-CoA mutase activity
B7G68_RS16270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B7G68_RS16275	COG1684	flagellar biosynthetic protein fliR
B7G68_RS16280	COG1987	bacterial-type flagellum assembly
B7G68_RS16310	COG1803	Methylglyoxal synthase
B7G68_RS16315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B7G68_RS16335	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B7G68_RS16360	COG2205	protein histidine kinase activity
B7G68_RS16370	COG2166	iron-sulfur cluster assembly
B7G68_RS16400	COG2188	Transcriptional regulator
B7G68_RS16415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7G68_RS16430	COG0457	Tetratricopeptide repeat
B7G68_RS16450	COG5002	protein histidine kinase activity
B7G68_RS16450	COG2205	protein histidine kinase activity
B7G68_RS16450	COG0784	Response regulator, receiver
B7G68_RS16455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B7G68_RS16465	COG2205	protein histidine kinase activity
B7G68_RS16470	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS16530	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B7G68_RS16535	COG1506	peptidase
B7G68_RS16560	COG0072	phenylalanine-tRNA ligase activity
B7G68_RS16560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7G68_RS16585	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B7G68_RS16590	COG2862	Uncharacterized protein family, UPF0114
B7G68_RS16605	COG0464	growth
B7G68_RS16640	COG0625	glutathione transferase activity
B7G68_RS16675	COG0477	Major facilitator Superfamily
B7G68_RS16685	COG0500	methyltransferase
B7G68_RS16710	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7G68_RS16715	COG0110	maltose O-acetyltransferase activity
B7G68_RS16720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7G68_RS16745	COG0275	rRNA processing
B7G68_RS16775	COG3250	beta-galactosidase activity
B7G68_RS16785	COG3867	Arabinogalactan endo-beta-1,4-galactanase
B7G68_RS16820	COG1595	DNA-templated transcription, initiation
B7G68_RS16840	COG4771	TonB-dependent receptor
B7G68_RS16855	COG2271	Major facilitator Superfamily
B7G68_RS16925	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B7G68_RS16940	COG4771	TonB-dependent receptor
B7G68_RS16945	COG3250	beta-galactosidase activity
B7G68_RS16955	COG2175	clavaminate synthase activity
B7G68_RS16960	COG3507	Belongs to the glycosyl hydrolase 43 family
B7G68_RS16965	COG2271	Major facilitator Superfamily
B7G68_RS16985	COG4948	Mandelate Racemase Muconate Lactonizing
B7G68_RS16990	COG2186	Transcriptional regulator
B7G68_RS17000	COG4206	TonB-dependent receptor
B7G68_RS17035	COG3667	copper resistance
B7G68_RS17040	COG2132	Multicopper oxidase
B7G68_RS17045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B7G68_RS17080	COG1174	glycine betaine transport
B7G68_RS17085	COG0517	IMP dehydrogenase activity
B7G68_RS17085	COG1125	glycine betaine transport
B7G68_RS17095	COG0583	DNA-binding transcription factor activity
B7G68_RS17105	COG1677	Flagellar hook-basal body complex protein FliE
B7G68_RS17110	COG1558	bacterial-type flagellum-dependent cell motility
B7G68_RS17120	COG3190	flagellar
B7G68_RS17125	COG1338	Plays a role in the flagellum-specific transport system
B7G68_RS17130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7G68_RS17150	COG1024	Enoyl-CoA hydratase
B7G68_RS17170	COG1914	H( )-stimulated, divalent metal cation uptake system
B7G68_RS17180	COG3813	Protein conserved in bacteria
B7G68_RS17210	COG0784	Response regulator, receiver
B7G68_RS17210	COG5002	protein histidine kinase activity
B7G68_RS17210	COG2198	Histidine kinase
B7G68_RS17215	COG4957	zinc ion binding
B7G68_RS17230	COG0616	signal peptide processing
B7G68_RS17235	COG0457	Tetratricopeptide repeat
B7G68_RS17255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7G68_RS17265	COG0484	heat shock protein binding
B7G68_RS17270	COG1764	response to oxidative stress
B7G68_RS17275	COG1846	Transcriptional regulator
B7G68_RS17300	COG1064	alcohol dehydrogenase
B7G68_RS17305	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B7G68_RS17310	COG2204	response regulator
B7G68_RS17315	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7G68_RS17320	COG1317	bacterial-type flagellum organization
B7G68_RS17325	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7G68_RS17330	COG1766	The M ring may be actively involved in energy transduction
B7G68_RS17345	COG1749	Flagellar hook protein flgE
B7G68_RS17370	COG0482	sulfurtransferase activity
B7G68_RS17395	COG2234	aminopeptidase activity
B7G68_RS17405	COG4221	oxidoreductase activity
B7G68_RS17410	COG2885	chlorophyll binding
B7G68_RS17450	COG0542	response to heat
B7G68_RS17470	COG4191	Histidine kinase
B7G68_RS17480	COG2890	protein-(glutamine-N5) methyltransferase activity
B7G68_RS17485	COG3609	addiction module antidote protein, CC2985 family
B7G68_RS17500	COG1295	ribonuclease BN
B7G68_RS17525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7G68_RS17545	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B7G68_RS17565	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B7G68_RS17570	COG3474	cytochrome
B7G68_RS17580	COG0596	Alpha beta hydrolase
B7G68_RS17595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B7G68_RS17635	COG4964	Belongs to the GSP D family
B7G68_RS17675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7G68_RS17690	COG2365	Tyrosine phosphatase family
B7G68_RS17700	COG3384	dioxygenase
B7G68_RS17760	COG3920	Histidine kinase
B7G68_RS17765	COG0556	nucleotide-excision repair
B7G68_RS17800	COG0492	ferredoxin-NADP+ reductase activity
B7G68_RS17810	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B7G68_RS17820	COG0457	Tetratricopeptide repeat
B7G68_RS17855	COG3755	Protein conserved in bacteria
B7G68_RS17880	COG2301	Belongs to the HpcH HpaI aldolase family
B7G68_RS17885	COG1511	domain protein
B7G68_RS17885	COG3264	Mechanosensitive ion channel
B7G68_RS17895	COG0667	Aldo Keto reductase
B7G68_RS17905	COG2824	Alkylphosphonate utilization operon protein PhnA
B7G68_RS17910	COG4974	Belongs to the 'phage' integrase family
B7G68_RS17935	COG1846	Transcriptional regulator
B7G68_RS17940	COG0488	(ABC) transporter
B7G68_RS17945	COG4536	flavin adenine dinucleotide binding
B7G68_RS17950	COG3920	Histidine kinase
B7G68_RS17990	COG0671	phosphoesterase, PA-phosphatase related
B7G68_RS18025	COG0835	chemotaxis
B7G68_RS18040	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B7G68_RS18120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B7G68_RS18130	COG0358	DNA primase activity
B7G68_RS18150	COG1472	Belongs to the glycosyl hydrolase 3 family
B7G68_RS18180	COG1477	protein flavinylation
B7G68_RS18190	COG0746	molybdenum cofactor guanylyltransferase activity
B7G68_RS18195	COG1609	Transcriptional regulator
B7G68_RS18220	COG0129	dihydroxy-acid dehydratase activity
B7G68_RS18230	COG0625	glutathione transferase activity
B7G68_RS18240	COG0477	Major facilitator Superfamily
B7G68_RS18245	COG3507	Belongs to the glycosyl hydrolase 43 family
B7G68_RS18255	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B7G68_RS18260	COG1611	Belongs to the LOG family
B7G68_RS18270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7G68_RS18275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7G68_RS18310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B7G68_RS18315	COG1501	Belongs to the glycosyl hydrolase 31 family
B7G68_RS18320	COG3734	2-keto-3-deoxy-galactonokinase
B7G68_RS18325	COG0800	Aldolase
B7G68_RS18335	COG2186	Transcriptional regulator
B7G68_RS18355	COG0183	Belongs to the thiolase family
B7G68_RS18395	COG0492	ferredoxin-NADP+ reductase activity
B7G68_RS18410	COG0657	acetylesterase activity
B7G68_RS18415	COG3321	synthase
B7G68_RS18415	COG0604	alcohol dehydrogenase
B7G68_RS18415	COG1028	Short-chain dehydrogenase reductase Sdr
B7G68_RS18445	COG0835	chemotaxis
B7G68_RS18455	COG1294	oxidase, subunit
B7G68_RS18465	COG4988	ABC transporter
B7G68_RS18470	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B7G68_RS18475	COG4191	Histidine kinase
B7G68_RS18480	COG4566	intracellular signal transduction
B7G68_RS18490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7G68_RS18500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B7G68_RS18510	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B7G68_RS18510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7G68_RS18515	COG3047	cAMP biosynthetic process
B7G68_RS18515	COG2885	chlorophyll binding
B7G68_RS18555	COG1217	gtp-binding protein TYPA
B7G68_RS18560	COG5001	Diguanylate cyclase
B7G68_RS18560	COG3300	MHYT domain
B7G68_RS18605	COG1335	isochorismatase
B7G68_RS18610	COG1741	Belongs to the pirin family
B7G68_RS18620	COG0583	DNA-binding transcription factor activity
B7G68_RS18625	COG2205	protein histidine kinase activity
B7G68_RS18625	COG0784	Response regulator, receiver
B7G68_RS18650	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7G68_RS18650	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B7G68_RS18660	COG1024	Enoyl-CoA hydratase
B7G68_RS18665	COG0604	alcohol dehydrogenase
B7G68_RS18685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7G68_RS18720	COG1309	transcriptional regulator
B7G68_RS18725	COG1309	transcriptional regulator
B7G68_RS18750	COG2086	electron transfer activity
B7G68_RS18765	COG0583	DNA-binding transcription factor activity
B7G68_RS18770	COG1509	lysine 2,3-aminomutase activity
B7G68_RS18775	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7G68_RS18795	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B7G68_RS18815	COG2030	dehydratase
B7G68_RS18820	COG0196	riboflavin kinase activity
B7G68_RS18825	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B7G68_RS18830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B7G68_RS18955	COG1056	cytidyltransferase-related domain
B7G68_RS18955	COG1051	belongs to the nudix hydrolase family
B7G68_RS19000	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B7G68_RS19050	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B7G68_RS19065	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B7G68_RS19070	COG1845	cytochrome c oxidase, subunit III
B7G68_RS19075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7G68_RS19085	COG0477	Major facilitator Superfamily
B7G68_RS19105	COG1609	Transcriptional regulator
B7G68_RS19110	COG1472	Belongs to the glycosyl hydrolase 3 family
B7G68_RS19115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7G68_RS19115	COG1263	PTS System
B7G68_RS19120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7G68_RS19120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7G68_RS19125	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B7G68_RS19135	COG2188	Transcriptional regulator
B7G68_RS19140	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B7G68_RS19155	COG2204	response regulator
B7G68_RS19170	COG0745	RESPONSE REGULATOR receiver
B7G68_RS19175	COG2201	protein-glutamate methylesterase activity
B7G68_RS19180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B7G68_RS19185	COG0835	chemotaxis
B7G68_RS19190	COG2198	Histidine kinase
B7G68_RS19190	COG0643	Histidine kinase
B7G68_RS19195	COG0745	RESPONSE REGULATOR receiver
B7G68_RS19205	COG0840	transmembrane signaling receptor activity
B7G68_RS19215	COG0840	transmembrane signaling receptor activity
B7G68_RS19220	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS19225	COG0531	amino acid
B7G68_RS19235	COG1522	sequence-specific DNA binding
B7G68_RS19240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B7G68_RS19265	COG2814	Major facilitator Superfamily
B7G68_RS19270	COG0583	DNA-binding transcription factor activity
B7G68_RS19275	COG1253	flavin adenine dinucleotide binding
B7G68_RS19280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7G68_RS19290	COG3639	organic phosphonate transmembrane transporter activity
B7G68_RS19295	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
B7G68_RS19300	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B7G68_RS19320	COG1899	peptidyl-lysine modification to peptidyl-hypusine
B7G68_RS19330	COG0735	belongs to the Fur family
B7G68_RS19375	COG3713	MltA-interacting MipA family protein
B7G68_RS19400	COG1253	flavin adenine dinucleotide binding
B7G68_RS19405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7G68_RS19420	COG4974	Belongs to the 'phage' integrase family
B7G68_RS19425	COG0840	transmembrane signaling receptor activity
B7G68_RS19435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7G68_RS19450	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7G68_RS19455	COG0567	Dehydrogenase, E1 component
B7G68_RS19460	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B7G68_RS19475	COG2814	Major facilitator Superfamily
B7G68_RS19520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7G68_RS19535	COG1960	acyl-CoA dehydrogenase activity
B7G68_RS19570	COG0625	glutathione transferase activity
B7G68_RS19580	COG0778	Nitroreductase
B7G68_RS19590	COG0848	biopolymer transport protein
B7G68_RS19600	COG0523	cobalamin synthesis protein
B7G68_RS19610	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B7G68_RS19640	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B7G68_RS19660	COG0312	modulator of DNA gyrase
B7G68_RS19680	COG1132	(ABC) transporter
B7G68_RS19690	COG1230	cation diffusion facilitator family transporter
B7G68_RS19695	COG1519	Transferase
B7G68_RS19710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B7G68_RS19735	COG0784	Response regulator, receiver
B7G68_RS19735	COG2205	protein histidine kinase activity
B7G68_RS19740	COG0745	RESPONSE REGULATOR receiver
B7G68_RS19760	COG0573	inorganic phosphate transmembrane transporter activity
B7G68_RS19765	COG5002	protein histidine kinase activity
B7G68_RS19780	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B7G68_RS19790	COG0784	Response regulator, receiver
B7G68_RS19800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B7G68_RS19810	COG2171	N-acyltransferase activity
B7G68_RS19830	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B7G68_RS19850	COG0625	glutathione transferase activity
B7G68_RS19860	COG1322	Protein conserved in bacteria
B7G68_RS19885	COG2816	NAD+ diphosphatase activity
B7G68_RS19890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7G68_RS19895	COG1301	dicarboxylic acid transport
B7G68_RS19905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B7G68_RS19915	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7G68_RS19975	COG1272	protein, Hemolysin III
B7G68_RS19985	COG2885	chlorophyll binding
B7G68_RS19990	COG2226	methyltransferase
B7G68_RS19995	COG0789	Transcriptional regulator
B7G68_RS20010	COG4651	solute:proton antiporter activity
B7G68_RS20010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7G68_RS20015	COG2030	dehydratase
B7G68_RS20040	COG4773	Receptor
B7G68_RS20055	COG0124	histidyl-tRNA synthetase
B7G68_RS20085	COG0386	Belongs to the glutathione peroxidase family
B7G68_RS20135	COG2957	Belongs to the agmatine deiminase family
B7G68_RS20145	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B7G68_RS20150	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7G68_RS20160	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7G68_RS20180	COG2885	chlorophyll binding
B7G68_RS20195	COG0336	Belongs to the RNA methyltransferase TrmD family
B7G68_RS20200	COG0335	large ribosomal subunit rRNA binding
B7G68_RS20230	COG0473	3-isopropylmalate dehydrogenase activity
B7G68_RS20235	COG0840	transmembrane signaling receptor activity
B7G68_RS20240	COG0318	PFAM AMP-dependent synthetase and ligase
B7G68_RS20255	COG2050	protein possibly involved in aromatic compounds catabolism
B7G68_RS20260	COG0667	Aldo Keto reductase
B7G68_RS20265	COG0583	DNA-binding transcription factor activity
B7G68_RS20300	COG1607	acyl-coa hydrolase
B7G68_RS20310	COG1131	(ABC) transporter
B7G68_RS20320	COG2252	PERMEase
B7G68_RS20335	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B7G68_RS20355	COG1301	dicarboxylic acid transport
B7G68_RS20360	COG4191	Histidine kinase
B7G68_RS20365	COG2204	response regulator
B7G68_RS20375	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B7G68_RS20390	COG3206	protein involved in exopolysaccharide biosynthesis
B7G68_RS20390	COG0489	protein tyrosine kinase activity
B7G68_RS20405	COG5278	phosphoserine phosphatase activity
B7G68_RS20405	COG0840	transmembrane signaling receptor activity
B7G68_RS20460	COG3655	Transcriptional regulator
B7G68_RS20480	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B7G68_RS20485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7G68_RS20490	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B7G68_RS20505	COG0189	ligase activity
B7G68_RS20510	COG0606	chelatase, subunit chli
B7G68_RS20520	COG2211	Major facilitator Superfamily
B7G68_RS20550	COG4221	oxidoreductase activity
B7G68_RS20575	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B7G68_RS20605	COG0784	Response regulator, receiver
B7G68_RS20640	COG5487	UPF0391 membrane protein
B7G68_RS20645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7G68_RS20670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7G68_RS20685	COG1131	(ABC) transporter
B7G68_RS20700	COG0288	reversible hydration of carbon dioxide
B7G68_RS20710	COG1522	sequence-specific DNA binding
B7G68_RS20715	COG0686	Belongs to the AlaDH PNT family
B7G68_RS20720	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
B7G68_RS20745	COG1012	belongs to the aldehyde dehydrogenase family
B7G68_RS20750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7G68_RS20760	COG3011	Protein conserved in bacteria
B7G68_RS20765	COG4251	negative regulation of phosphorylation
B7G68_RS20775	COG0612	Peptidase, M16
B7G68_RS20795	COG0539	negative regulation of cytoplasmic translation
B7G68_RS20820	COG0071	Belongs to the small heat shock protein (HSP20) family
B7G68_RS20835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B7G68_RS20845	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B7G68_RS20850	COG1137	ATPase activity
B7G68_RS20895	COG1793	dna ligase
B7G68_RS20900	COG2814	Major facilitator Superfamily
B7G68_RS20910	COG0668	transmembrane transport
B7G68_RS20945	COG2942	2-epimerase
B7G68_RS21025	COG1088	dTDP-glucose 4,6-dehydratase activity
B7G68_RS21040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7G68_RS21055	COG0596	Alpha beta hydrolase
B7G68_RS21060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7G68_RS21065	COG0545	Peptidyl-prolyl cis-trans isomerase
B7G68_RS21070	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B7G68_RS21075	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B7G68_RS21085	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B7G68_RS21085	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B7G68_RS21130	COG0123	including yeast histone deacetylase and acetoin utilization protein
B7G68_RS21135	COG1946	Acyl-CoA thioesterase
B7G68_RS21150	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B7G68_RS21160	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B7G68_RS21170	COG0517	IMP dehydrogenase activity
B7G68_RS21180	COG2030	dehydratase
B7G68_RS21245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B7G68_RS21260	COG0840	transmembrane signaling receptor activity
B7G68_RS21280	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B7G68_RS21310	COG0667	Aldo Keto reductase
B7G68_RS21315	COG0670	Belongs to the BI1 family
B7G68_RS21340	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7G68_RS21345	COG4133	protoheme IX ABC transporter activity
B7G68_RS21350	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7G68_RS21365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7G68_RS21375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7G68_RS21390	COG2917	probably involved in intracellular septation
B7G68_RS21395	COG0552	protein localization to endoplasmic reticulum
B7G68_RS21415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B7G68_RS21425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7G68_RS21430	COG1505	serine-type exopeptidase activity
B7G68_RS21435	COG1505	serine-type exopeptidase activity
B7G68_RS21445	COG1695	Transcriptional regulator
B7G68_RS21465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B7G68_RS21470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B7G68_RS21475	COG1127	ABC transporter
B7G68_RS21505	COG0339	signal peptide processing
B7G68_RS21510	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7G68_RS21520	COG1674	ftsk spoiiie
B7G68_RS21545	COG0840	transmembrane signaling receptor activity
B7G68_RS21555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7G68_RS21560	COG0237	dephospho-CoA kinase activity
B7G68_RS21570	COG0424	maF-like protein
B7G68_RS21575	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B7G68_RS21590	COG1981	membrane
B7G68_RS21595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B7G68_RS21665	COG0352	thiamine-phosphate diphosphorylase activity
B7G68_RS21670	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B7G68_RS21680	COG0745	RESPONSE REGULATOR receiver
B7G68_RS21700	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B7G68_RS21720	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B7G68_RS21725	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B7G68_RS21735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7G68_RS21745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B7G68_RS21770	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B7G68_RS21775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7G68_RS21800	COG1024	Enoyl-CoA hydratase