locus-tag	class	description
CO704_RS00005	COG4773	Receptor
CO704_RS00010	COG0583	DNA-binding transcription factor activity
CO704_RS00015	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS00030	COG0477	Major facilitator Superfamily
CO704_RS00035	COG0583	DNA-binding transcription factor activity
CO704_RS00055	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS00070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CO704_RS00075	COG1538	Outer membrane efflux protein
CO704_RS00085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO704_RS00110	COG1349	DNA-binding transcription factor activity
CO704_RS00115	COG1070	Carbohydrate kinase
CO704_RS00125	COG1349	DNA-binding transcription factor activity
CO704_RS00130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CO704_RS00135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO704_RS00140	COG0738	Major facilitator superfamily
CO704_RS00155	COG2864	formate dehydrogenase
CO704_RS00160	COG0437	4 iron, 4 sulfur cluster binding
CO704_RS00190	COG1012	belongs to the aldehyde dehydrogenase family
CO704_RS00195	COG3276	selenocysteine insertion sequence binding
CO704_RS00205	COG0625	glutathione transferase activity
CO704_RS00210	COG0583	DNA-binding transcription factor activity
CO704_RS00215	COG2249	NAD(P)H dehydrogenase (quinone) activity
CO704_RS00220	COG2213	PTS system mannitol-specific
CO704_RS00220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS00230	COG3722	fumarate hydratase activity
CO704_RS00250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CO704_RS00265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CO704_RS00325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CO704_RS00330	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CO704_RS00335	COG0671	phosphoesterase, PA-phosphatase related
CO704_RS00350	COG0589	response to stress
CO704_RS00360	COG0306	phosphate transporter
CO704_RS00365	COG2081	HI0933 family
CO704_RS00370	COG1349	DNA-binding transcription factor activity
CO704_RS00375	COG0561	phosphatase activity
CO704_RS00390	COG3712	iron ion homeostasis
CO704_RS00395	COG1595	DNA-templated transcription, initiation
CO704_RS00400	COG1629	transport
CO704_RS00405	COG0697	spore germination
CO704_RS00410	COG0740	serine-type endopeptidase activity
CO704_RS00425	COG0628	permease
CO704_RS00435	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CO704_RS00445	COG5499	transcription regulator containing HTH domain
CO704_RS00450	COG4680	protein conserved in bacteria
CO704_RS00465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CO704_RS00470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO704_RS00470	COG1263	PTS System
CO704_RS00470	COG2190	(PTS) system
CO704_RS00475	COG3714	YhhN family
CO704_RS00485	COG3776	membrane
CO704_RS00490	COG0742	ribosomal rna small subunit methyltransferase
CO704_RS00495	COG0552	protein localization to endoplasmic reticulum
CO704_RS00500	COG2884	Cell division ATP-binding protein ftsE
CO704_RS00505	COG2177	Part of the ABC transporter FtsEX involved in
CO704_RS00520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CO704_RS00545	COG0683	leucine binding
CO704_RS00555	COG4177	L-phenylalanine transmembrane transporter activity
CO704_RS00560	COG0411	ABC transporter
CO704_RS00565	COG0410	ABC transporter
CO704_RS00590	COG0584	glycerophosphoryl diester phosphodiesterase
CO704_RS00600	COG0405	Gamma-glutamyltransferase
CO704_RS00605	COG1247	-acetyltransferase
CO704_RS00610	COG0673	inositol 2-dehydrogenase activity
CO704_RS00615	COG1741	Belongs to the pirin family
CO704_RS00620	COG1609	Transcriptional regulator
CO704_RS00625	COG3265	gluconokinase activity
CO704_RS00630	COG2610	gluconate transmembrane transporter activity
CO704_RS00640	COG2095	MarC family integral membrane protein
CO704_RS00645	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CO704_RS00665	COG0297	glycogen (starch) synthase activity
CO704_RS00670	COG0058	SHG alpha-glucan phosphorylase activity
CO704_RS00675	COG1349	DNA-binding transcription factor activity
CO704_RS00690	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CO704_RS00700	COG0058	SHG alpha-glucan phosphorylase activity
CO704_RS00705	COG1640	4-alpha-glucanotransferase
CO704_RS00740	COG1918	ferrous iron import across plasma membrane
CO704_RS00745	COG2183	response to ionizing radiation
CO704_RS00750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CO704_RS00770	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CO704_RS00780	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CO704_RS00785	COG1011	Hydrolase
CO704_RS00795	COG0494	nUDIX hydrolase
CO704_RS00800	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CO704_RS00825	COG4796	Type ii and iii secretion system protein
CO704_RS00835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CO704_RS00845	COG3266	domain, Protein
CO704_RS00850	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CO704_RS00855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CO704_RS00870	COG2188	Transcriptional regulator
CO704_RS00880	COG3457	Alanine racemase
CO704_RS00885	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CO704_RS00890	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CO704_RS00905	COG0626	cystathionine gamma-synthase activity
CO704_RS00920	COG2146	nitrite reductase [NAD(P)H] activity
CO704_RS00925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CO704_RS00930	COG0583	DNA-binding transcription factor activity
CO704_RS00935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CO704_RS00935	COG1017	nitric oxide dioxygenase activity
CO704_RS00940	COG0625	glutathione transferase activity
CO704_RS00945	COG0738	Major facilitator superfamily
CO704_RS00955	COG0512	Glutamine amidotransferase of anthranilate synthase
CO704_RS00965	COG1289	transmembrane transporter activity
CO704_RS00975	COG1765	OsmC-like protein
CO704_RS00980	COG3954	Phosphoribulokinase
CO704_RS00985	COG3089	Belongs to the UPF0270 family
CO704_RS00990	COG0429	hydrolase of the alpha beta-hydrolase fold
CO704_RS01000	COG0488	(ABC) transporter
CO704_RS01010	COG0475	glutathione-regulated potassium exporter activity
CO704_RS01010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CO704_RS01015	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CO704_RS01020	COG1047	Peptidyl-prolyl cis-trans
CO704_RS01030	COG0545	Peptidyl-prolyl cis-trans isomerase
CO704_RS01035	COG2964	Protein conserved in bacteria
CO704_RS01050	COG2168	tRNA wobble position uridine thiolation
CO704_RS01055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CO704_RS01060	COG0049	tRNA binding
CO704_RS01065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CO704_RS01085	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CO704_RS01090	COG0051	transcription antitermination factor activity, RNA binding
CO704_RS01115	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CO704_RS01130	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CO704_RS01145	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CO704_RS01165	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CO704_RS01175	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CO704_RS01185	COG1841	ribosomal large subunit assembly
CO704_RS01190	COG0200	Binds to the 23S rRNA
CO704_RS01195	COG0201	protein transport
CO704_RS01235	COG0789	Transcriptional regulator
CO704_RS01240	COG3036	rescue of stalled ribosome
CO704_RS01270	COG0758	DNA mediated transformation
CO704_RS01280	COG0551	DNA topoisomerase type I activity
CO704_RS01285	COG0009	L-threonylcarbamoyladenylate synthase
CO704_RS01300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CO704_RS01340	COG1126	abc transporter atp-binding protein
CO704_RS01345	COG0765	amino acid transport
CO704_RS01350	COG4597	amino acid ABC transporter
CO704_RS01355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO704_RS01380	COG4145	pantothenate transmembrane transporter activity
CO704_RS01385	COG3924	membrane
CO704_RS01390	COG0439	Biotin carboxylase
CO704_RS01395	COG0511	ligase activity, forming carbon-carbon bonds
CO704_RS01405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CO704_RS01420	COG0604	alcohol dehydrogenase
CO704_RS01425	COG2199	diguanylate cyclase activity
CO704_RS01425	COG2200	EAL domain
CO704_RS01435	COG1077	Cell shape determining protein MreB Mrl
CO704_RS01440	COG1792	Involved in formation and maintenance of cell shape
CO704_RS01445	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CO704_RS01460	COG3164	Protein of unknown function
CO704_RS01465	COG0312	modulator of DNA gyrase
CO704_RS01470	COG0583	DNA-binding transcription factor activity
CO704_RS01485	COG1289	transmembrane transporter activity
CO704_RS01490	COG1012	belongs to the aldehyde dehydrogenase family
CO704_RS01495	COG2732	(Barnase) inhibitor
CO704_RS01510	COG1438	arginine binding
CO704_RS01520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CO704_RS01525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CO704_RS01530	COG3105	Protein conserved in bacteria
CO704_RS01535	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CO704_RS01540	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CO704_RS01550	COG0625	glutathione transferase activity
CO704_RS01555	COG2969	positive regulation of protein catabolic process
CO704_RS01560	COG0493	'glutamate synthase
CO704_RS01565	COG0070	glutamate synthase
CO704_RS01565	COG0069	glutamate synthase activity
CO704_RS01565	COG0067	glutamate synthase
CO704_RS01575	COG1242	4 iron, 4 sulfur cluster binding
CO704_RS01580	COG0784	Response regulator, receiver
CO704_RS01580	COG5002	protein histidine kinase activity
CO704_RS01580	COG2198	Histidine kinase
CO704_RS01585	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CO704_RS01595	COG3835	regulator
CO704_RS01600	COG2610	gluconate transmembrane transporter activity
CO704_RS01605	COG1929	Belongs to the glycerate kinase type-1 family
CO704_RS01610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS01620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS01625	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CO704_RS01630	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CO704_RS01635	COG1137	ATPase activity
CO704_RS01640	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CO704_RS01645	COG3117	lipopolysaccharide transmembrane transporter activity
CO704_RS01650	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CO704_RS01655	COG0517	IMP dehydrogenase activity
CO704_RS01655	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CO704_RS01660	COG0530	calcium, potassium:sodium antiporter activity
CO704_RS01670	COG1127	ABC transporter
CO704_RS01675	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CO704_RS01680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CO704_RS01685	COG2854	intermembrane phospholipid transfer
CO704_RS01690	COG3113	response to antibiotic
CO704_RS01695	COG5007	Belongs to the BolA IbaG family
CO704_RS01705	COG3423	Transcriptional regulator
CO704_RS01710	COG0142	geranyltranstransferase activity
CO704_RS01720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CO704_RS01725	COG0697	spore germination
CO704_RS01735	COG0642	Histidine kinase
CO704_RS01740	COG0745	RESPONSE REGULATOR receiver
CO704_RS01745	COG2027	D-alanyl-D-alanine carboxypeptidase
CO704_RS01755	COG1534	Rna-binding protein
CO704_RS01770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CO704_RS01780	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CO704_RS01795	COG0779	Required for maturation of 30S ribosomal subunits
CO704_RS01800	COG0195	Participates in both transcription termination and antitermination
CO704_RS01820	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CO704_RS01835	COG0513	Belongs to the DEAD box helicase family
CO704_RS01840	COG0814	amino acid
CO704_RS01845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CO704_RS01850	COG0826	peptidase U32
CO704_RS01855	COG0826	peptidase U32
CO704_RS01860	COG3154	lipid carrier protein
CO704_RS01865	COG3153	acetyltransferase
CO704_RS01880	COG0693	protein deglycase activity
CO704_RS01885	COG0702	epimerase
CO704_RS01890	COG0701	Predicted permease
CO704_RS01895	COG2249	NAD(P)H dehydrogenase (quinone) activity
CO704_RS01900	COG1733	regulation of RNA biosynthetic process
CO704_RS01905	COG0602	queuosine metabolic process
CO704_RS01920	COG2249	NAD(P)H dehydrogenase (quinone) activity
CO704_RS01925	COG0366	Alpha amylase catalytic
CO704_RS01930	COG1263	PTS System
CO704_RS01930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO704_RS01945	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CO704_RS01950	COG0251	oxidation-reduction process
CO704_RS01985	COG2235	arginine
CO704_RS01990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CO704_RS02010	COG2197	response regulator
CO704_RS02045	COG2927	DNA polymerase III (CHI subunit)
CO704_RS02060	COG0795	lipopolysaccharide-transporting ATPase activity
CO704_RS02065	COG0795	lipopolysaccharide-transporting ATPase activity
CO704_RS02070	COG0814	amino acid
CO704_RS02075	COG0433	COG0433 Predicted ATPase
CO704_RS02085	COG1064	alcohol dehydrogenase
CO704_RS02090	COG0673	inositol 2-dehydrogenase activity
CO704_RS02100	COG0582	viral genome integration into host DNA
CO704_RS02190	COG2003	Belongs to the UPF0758 family
CO704_RS02220	COG3423	Transcriptional regulator
CO704_RS02275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CO704_RS02305	COG4529	Protein conserved in bacteria
CO704_RS02310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CO704_RS02315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO704_RS02315	COG1263	PTS System
CO704_RS02320	COG4521	taurine ABC transporter
CO704_RS02325	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CO704_RS02330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CO704_RS02335	COG2175	clavaminate synthase activity
CO704_RS02395	COG0840	transmembrane signaling receptor activity
CO704_RS02410	COG1473	amidohydrolase
CO704_RS02425	COG3384	dioxygenase
CO704_RS02430	COG0754	glutathionylspermidine amidase activity
CO704_RS02440	COG1538	Outer membrane efflux protein
CO704_RS02445	COG0494	nUDIX hydrolase
CO704_RS02450	COG3151	Protein conserved in bacteria
CO704_RS02455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CO704_RS02460	COG3150	esterase
CO704_RS02470	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CO704_RS02475	COG2249	NAD(P)H dehydrogenase (quinone) activity
CO704_RS02480	COG0642	Histidine kinase
CO704_RS02490	COG3111	PFAM Bacterial OB fold (BOF) protein
CO704_RS02495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CO704_RS02510	COG1032	radical SAM domain protein
CO704_RS02520	COG3639	organic phosphonate transmembrane transporter activity
CO704_RS02530	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CO704_RS02540	COG0656	L-ascorbic acid biosynthetic process
CO704_RS02545	COG1979	alcohol dehydrogenase
CO704_RS02550	COG2207	Transcriptional regulator
CO704_RS02555	COG0586	Pfam SNARE associated Golgi protein
CO704_RS02560	COG0626	cystathionine gamma-synthase activity
CO704_RS02570	COG0848	biopolymer transport protein
CO704_RS02595	COG0667	Aldo Keto reductase
CO704_RS02610	COG3962	Belongs to the TPP enzyme family
CO704_RS02615	COG0673	inositol 2-dehydrogenase activity
CO704_RS02625	COG1129	ABC transporter
CO704_RS02630	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO704_RS02635	COG0673	inositol 2-dehydrogenase activity
CO704_RS02640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO704_RS02650	COG3718	enzyme involved in inositol metabolism
CO704_RS02655	COG0456	acetyltransferase
CO704_RS02660	COG1473	amidohydrolase
CO704_RS02665	COG0436	Aminotransferase
CO704_RS02670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CO704_RS02675	COG0371	Dehydrogenase
CO704_RS02680	COG2079	MmgE PrpD family protein
CO704_RS02685	COG1126	abc transporter atp-binding protein
CO704_RS02695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO704_RS02700	COG0754	glutathionylspermidine amidase activity
CO704_RS02705	COG3969	phosphoadenosine phosphosulfate
CO704_RS02710	COG1475	DNA binding
CO704_RS02730	COG1982	Orn Lys Arg decarboxylase major
CO704_RS02735	COG0741	lytic transglycosylase activity
CO704_RS02745	COG1194	a g-specific adenine glycosylase
CO704_RS02755	COG3171	Protein conserved in bacteria
CO704_RS02765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CO704_RS02780	COG0762	integral membrane protein
CO704_RS02785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CO704_RS02790	COG2805	Type II/IV secretion system protein
CO704_RS02805	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CO704_RS02820	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CO704_RS02825	COG2356	endonuclease I
CO704_RS02830	COG3091	SprT-like family
CO704_RS02835	COG2814	Major facilitator Superfamily
CO704_RS02840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CO704_RS02850	COG1166	arginine decarboxylase activity
CO704_RS02870	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS02870	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO704_RS02875	COG3715	PTS system
CO704_RS02880	COG3716	PTS system mannose fructose sorbose family IID component
CO704_RS02895	COG0501	Belongs to the peptidase M48B family
CO704_RS02900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CO704_RS02910	COG0126	phosphoglycerate kinase activity
CO704_RS02915	COG0191	fructose-bisphosphate aldolase activity
CO704_RS02920	COG0583	DNA-binding transcription factor activity
CO704_RS02930	COG0814	amino acid
CO704_RS02935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CO704_RS02940	COG1882	Formate acetyltransferase
CO704_RS02945	COG0668	transmembrane transport
CO704_RS02950	COG1279	arginine transmembrane transporter activity
CO704_RS02955	COG2968	Membrane
CO704_RS02970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CO704_RS02975	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CO704_RS02990	COG3079	Belongs to the UPF0149 family
CO704_RS02995	COG0006	proline dipeptidase activity
CO704_RS03000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CO704_RS03005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CO704_RS03025	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS03035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CO704_RS03040	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CO704_RS03045	COG0745	RESPONSE REGULATOR receiver
CO704_RS03050	COG5002	protein histidine kinase activity
CO704_RS03055	COG2723	6-phospho-beta-galactosidase activity
CO704_RS03060	COG1737	Transcriptional regulator
CO704_RS03070	COG1272	protein, Hemolysin III
CO704_RS03080	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CO704_RS03105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CO704_RS03115	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CO704_RS03120	COG4942	peptidase
CO704_RS03145	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CO704_RS03160	COG0300	oxidoreductase activity
CO704_RS03165	COG2207	Transcriptional regulator
CO704_RS03180	COG0583	DNA-binding transcription factor activity
CO704_RS03200	COG0840	transmembrane signaling receptor activity
CO704_RS03205	COG0840	transmembrane signaling receptor activity
CO704_RS03210	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS03235	COG1280	lysine exporter protein (LysE YggA)
CO704_RS03245	COG2814	Major facilitator Superfamily
CO704_RS03255	COG0667	Aldo Keto reductase
CO704_RS03265	COG0477	Major facilitator Superfamily
CO704_RS03275	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CO704_RS03280	COG1794	racemase activity, acting on amino acids and derivatives
CO704_RS03285	COG2814	Major facilitator Superfamily
CO704_RS03290	COG0583	DNA-binding transcription factor activity
CO704_RS03300	COG1609	Transcriptional regulator
CO704_RS03310	COG1609	Transcriptional regulator
CO704_RS03320	COG0477	Major facilitator Superfamily
CO704_RS03325	COG0667	Aldo Keto reductase
CO704_RS03360	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CO704_RS03370	COG4795	General secretion pathway protein
CO704_RS03380	COG4967	type IV pilus modification protein PilV
CO704_RS03385	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CO704_RS03395	COG1074	ATP-dependent DNA helicase activity
CO704_RS03400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CO704_RS03405	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CO704_RS03405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CO704_RS03410	COG0860	N-Acetylmuramoyl-L-alanine amidase
CO704_RS03430	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CO704_RS03435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CO704_RS03440	COG2166	iron-sulfur cluster assembly
CO704_RS03445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CO704_RS03455	COG0583	DNA-binding transcription factor activity
CO704_RS03460	COG2363	Small membrane protein
CO704_RS03465	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CO704_RS03475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CO704_RS03480	COG1760	l-serine dehydratase
CO704_RS03485	COG0814	amino acid
CO704_RS03490	COG1611	Belongs to the LOG family
CO704_RS03505	COG3098	single-species biofilm formation
CO704_RS03510	COG0564	pseudouridine synthase activity
CO704_RS03515	COG0716	FMN binding
CO704_RS03535	COG3850	Histidine kinase
CO704_RS03535	COG3437	response regulator, receiver
CO704_RS03535	COG4999	Histidine kinase
CO704_RS03535	COG2205	protein histidine kinase activity
CO704_RS03540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CO704_RS03545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CO704_RS03550	COG3956	TIGRFAM MazG family protein
CO704_RS03560	COG0148	phosphopyruvate hydratase activity
CO704_RS03565	COG1064	alcohol dehydrogenase
CO704_RS03575	COG0700	Nucleoside recognition
CO704_RS03580	COG3366	ferrous iron transmembrane transporter activity
CO704_RS03585	COG0602	queuosine metabolic process
CO704_RS03590	COG1070	Carbohydrate kinase
CO704_RS03595	COG2223	nitrite transmembrane transporter activity
CO704_RS03600	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS03605	COG0277	FAD linked oxidase domain protein
CO704_RS03610	COG0477	Major facilitator Superfamily
CO704_RS03615	COG2086	electron transfer activity
CO704_RS03625	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CO704_RS03630	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CO704_RS03635	COG0644	oxidoreductase
CO704_RS03640	COG0720	synthase
CO704_RS03670	COG2234	aminopeptidase activity
CO704_RS03725	COG1388	LysM domain
CO704_RS03725	COG4942	peptidase
CO704_RS03745	COG0840	transmembrane signaling receptor activity
CO704_RS03750	COG0753	catalase activity
CO704_RS03755	COG3038	cytochrome b561
CO704_RS03760	COG1595	DNA-templated transcription, initiation
CO704_RS03785	COG2951	lytic endotransglycosylase activity
CO704_RS03790	COG0517	IMP dehydrogenase activity
CO704_RS03790	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CO704_RS03795	COG1349	DNA-binding transcription factor activity
CO704_RS03800	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS03805	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS03815	COG3732	PTS system glucitol sorbitol-specific
CO704_RS03820	COG3730	PTS system glucitol sorbitol-specific
CO704_RS03830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CO704_RS03835	COG0803	Belongs to the bacterial solute-binding protein 9 family
CO704_RS03840	COG1546	Belongs to the CinA family
CO704_RS03850	COG2137	regulation of response to DNA damage stimulus
CO704_RS03860	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CO704_RS03890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CO704_RS03895	COG1238	metal cluster binding
CO704_RS03910	COG1917	Cupin 2, conserved barrel domain protein
CO704_RS03910	COG4977	sequence-specific DNA binding
CO704_RS03915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CO704_RS03920	COG2814	Major facilitator Superfamily
CO704_RS03925	COG1566	PFAM secretion protein HlyD family protein
CO704_RS03930	COG1846	Transcriptional regulator
CO704_RS03935	COG2814	Major facilitator Superfamily
CO704_RS03945	COG4176	ABC-type proline glycine betaine transport system permease component
CO704_RS03970	COG1780	Probably involved in ribonucleotide reductase function
CO704_RS03975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CO704_RS03980	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CO704_RS03990	COG4575	ribosome binding
CO704_RS04015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CO704_RS04020	COG0640	Transcriptional regulator
CO704_RS04025	COG0406	alpha-ribazole phosphatase activity
CO704_RS04035	COG2207	Transcriptional regulator
CO704_RS04045	COG0477	Major facilitator Superfamily
CO704_RS04055	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CO704_RS04065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CO704_RS04120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO704_RS04155	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CO704_RS04175	COG0582	viral genome integration into host DNA
CO704_RS04200	COG2003	Belongs to the UPF0758 family
CO704_RS04220	COG2378	regulation of single-species biofilm formation
CO704_RS04225	COG3596	GTP binding
CO704_RS04245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CO704_RS04250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO704_RS04255	COG0589	response to stress
CO704_RS04295	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CO704_RS04305	COG3311	Transcriptional regulator
CO704_RS04315	COG0582	viral genome integration into host DNA
CO704_RS04325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO704_RS04350	COG2867	negative regulation of translational initiation
CO704_RS04365	COG0497	DNA recombination
CO704_RS04370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CO704_RS04380	COG4536	flavin adenine dinucleotide binding
CO704_RS04385	COG4137	Cytochrome C assembly protein
CO704_RS04390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CO704_RS04410	COG0335	large ribosomal subunit rRNA binding
CO704_RS04415	COG2885	chlorophyll binding
CO704_RS04420	COG2199	diguanylate cyclase activity
CO704_RS04435	COG0287	Prephenate dehydrogenase
CO704_RS04435	COG1605	Chorismate mutase
CO704_RS04445	COG1605	Chorismate mutase
CO704_RS04445	COG0077	Prephenate dehydratase
CO704_RS04450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CO704_RS04460	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CO704_RS04465	COG0564	pseudouridine synthase activity
CO704_RS04475	COG0542	response to heat
CO704_RS04505	COG0477	Major facilitator Superfamily
CO704_RS04510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CO704_RS04520	COG3148	PFAM DTW domain containing protein
CO704_RS04525	COG3118	belongs to the thioredoxin family
CO704_RS04530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CO704_RS04550	COG0583	DNA-binding transcription factor activity
CO704_RS04555	COG0513	Belongs to the DEAD box helicase family
CO704_RS04560	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CO704_RS04565	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CO704_RS04585	COG3026	antisigma factor binding
CO704_RS04590	COG3086	response to oxidative stress
CO704_RS04605	COG0681	Belongs to the peptidase S26 family
CO704_RS04615	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CO704_RS04620	COG1381	Involved in DNA repair and RecF pathway recombination
CO704_RS04625	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CO704_RS04635	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO704_RS04655	COG3772	lysozyme
CO704_RS04665	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CO704_RS04760	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CO704_RS04765	COG1737	Transcriptional regulator
CO704_RS04770	COG0560	Phosphoserine phosphatase
CO704_RS04790	COG2205	protein histidine kinase activity
CO704_RS04795	COG3170	Tfp pilus assembly protein FimV
CO704_RS04800	COG2204	response regulator
CO704_RS04805	COG0347	Belongs to the P(II) protein family
CO704_RS04810	COG1017	nitric oxide dioxygenase activity
CO704_RS04810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CO704_RS04835	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO704_RS04840	COG1129	ABC transporter
CO704_RS04850	COG2259	Doxx family
CO704_RS04855	COG1940	carbohydrate kinase activity
CO704_RS04860	COG0457	Tetratricopeptide repeat
CO704_RS04865	COG2814	Major facilitator Superfamily
CO704_RS04865	COG0477	Major facilitator Superfamily
CO704_RS04875	COG2814	Major facilitator Superfamily
CO704_RS04880	COG3711	transcriptional antiterminator
CO704_RS04885	COG3683	transport system, periplasmic component
CO704_RS04890	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CO704_RS04895	COG0483	inositol monophosphate 1-phosphatase activity
CO704_RS04915	COG0822	iron-sulfur transferase activity
CO704_RS04935	COG0633	Ferredoxin
CO704_RS04940	COG2975	iron-sulfur cluster assembly
CO704_RS04955	COG2897	thiosulfate sulfurtransferase activity
CO704_RS04960	COG2373	Large extracellular alpha-helical protein
CO704_RS04965	COG4953	penicillin-binding protein 1C
CO704_RS04990	COG0124	histidyl-tRNA synthetase
CO704_RS04995	COG2976	Protein conserved in bacteria
CO704_RS05015	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CO704_RS05020	COG0154	amidase activity
CO704_RS05025	COG1645	bacterial-type flagellum-dependent swarming motility
CO704_RS05035	COG0516	GMP reductase activity
CO704_RS05035	COG0517	IMP dehydrogenase activity
CO704_RS05040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CO704_RS05040	COG0519	Catalyzes the synthesis of GMP from XMP
CO704_RS05050	COG3423	Transcriptional regulator
CO704_RS05065	COG0006	proline dipeptidase activity
CO704_RS05075	COG1280	lysine exporter protein (LysE YggA)
CO704_RS05090	COG1619	proteins homologs of microcin C7 resistance protein MccF
CO704_RS05095	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CO704_RS05105	COG1174	glycine betaine transport
CO704_RS05110	COG1174	glycine betaine transport
CO704_RS05120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CO704_RS05145	COG2200	EAL domain
CO704_RS05160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CO704_RS05165	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CO704_RS05175	COG2233	PERMEase
CO704_RS05185	COG0436	Aminotransferase
CO704_RS05190	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CO704_RS05195	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CO704_RS05205	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CO704_RS05220	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO704_RS05225	COG1129	ABC transporter
CO704_RS05230	COG0371	Dehydrogenase
CO704_RS05250	COG0725	ABC transporter, periplasmic molybdate-binding protein
CO704_RS05255	COG4149	molybdate abc transporter
CO704_RS05265	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CO704_RS05270	COG2188	Transcriptional regulator
CO704_RS05275	COG4948	Mandelate Racemase Muconate Lactonizing
CO704_RS05280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO704_RS05280	COG1263	PTS System
CO704_RS05280	COG2190	(PTS) system
CO704_RS05300	COG2011	ABC-type metal ion transport system permease component
CO704_RS05310	COG1464	Belongs to the NlpA lipoprotein family
CO704_RS05320	COG0840	transmembrane signaling receptor activity
CO704_RS05330	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CO704_RS05340	COG0110	maltose O-acetyltransferase activity
CO704_RS05355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CO704_RS05360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO704_RS05365	COG1309	transcriptional regulator
CO704_RS05370	COG3264	Mechanosensitive ion channel
CO704_RS05370	COG1196	nuclear chromosome segregation
CO704_RS05385	COG2832	Protein of unknown function (DUF454)
CO704_RS05390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CO704_RS05400	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CO704_RS05405	COG0583	DNA-binding transcription factor activity
CO704_RS05440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO704_RS05445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CO704_RS05445	COG4651	solute:proton antiporter activity
CO704_RS05450	COG2223	nitrite transmembrane transporter activity
CO704_RS05455	COG0737	Belongs to the 5'-nucleotidase family
CO704_RS05460	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CO704_RS05465	COG3735	TraB family
CO704_RS05470	COG2217	Heavy metal translocating P-type atpase
CO704_RS05480	COG1585	Membrane protein implicated in regulation of membrane protease activity
CO704_RS05485	COG0330	HflC and HflK could
CO704_RS05490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CO704_RS05495	COG3118	belongs to the thioredoxin family
CO704_RS05500	COG0300	oxidoreductase activity
CO704_RS05505	COG2755	lipolytic protein G-D-S-L family
CO704_RS05510	COG4181	ATPase activity
CO704_RS05515	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CO704_RS05535	COG1464	Belongs to the NlpA lipoprotein family
CO704_RS05580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CO704_RS05585	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CO704_RS05600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CO704_RS05625	COG1393	Belongs to the ArsC family
CO704_RS05630	COG4783	chaperone-mediated protein folding
CO704_RS05635	COG0628	permease
CO704_RS05640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CO704_RS05645	COG2716	regulation of RNA biosynthetic process
CO704_RS05655	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CO704_RS05665	COG2321	neutral zinc metallopeptidase
CO704_RS05670	COG1444	tRNA N-acetyltransferase activity
CO704_RS05675	COG0400	carboxylic ester hydrolase activity
CO704_RS05690	COG1393	Belongs to the ArsC family
CO704_RS05695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CO704_RS05700	COG2197	response regulator
CO704_RS05705	COG3850	Histidine kinase
CO704_RS05710	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO704_RS05710	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO704_RS05715	COG3062	negative regulation of establishment of protein localization
CO704_RS05725	COG3043	anaerobic respiration
CO704_RS05730	COG3005	denitrification pathway
CO704_RS05735	COG0494	nUDIX hydrolase
CO704_RS05740	COG5342	invasion associated locus B
CO704_RS05745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CO704_RS05750	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CO704_RS05785	COG2837	iron assimilation
CO704_RS05790	COG4150	thiosulfate binding
CO704_RS05795	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CO704_RS05800	COG4208	sulfate ABC transporter
CO704_RS05805	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CO704_RS05810	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CO704_RS05815	COG2140	Oxalate decarboxylase
CO704_RS05830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CO704_RS05850	COG3115	cell septum assembly
CO704_RS05860	COG3530	Putative quorum-sensing-regulated virulence factor
CO704_RS05865	COG0385	Bile acid
CO704_RS05870	COG0583	DNA-binding transcription factor activity
CO704_RS05920	COG3415	Transposase
CO704_RS05935	COG2199	diguanylate cyclase activity
CO704_RS05935	COG2200	EAL domain
CO704_RS05945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CO704_RS05960	COG0667	Aldo Keto reductase
CO704_RS05965	COG3961	Belongs to the TPP enzyme family
CO704_RS05980	COG3279	Response regulator of the LytR AlgR family
CO704_RS05985	COG3275	phosphorelay sensor kinase activity
CO704_RS06000	COG0436	Aminotransferase
CO704_RS06020	COG1914	H( )-stimulated, divalent metal cation uptake system
CO704_RS06025	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CO704_RS06030	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CO704_RS06035	COG4770	biotin carboxylase activity
CO704_RS06045	COG0531	amino acid
CO704_RS06060	COG1012	belongs to the aldehyde dehydrogenase family
CO704_RS06070	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CO704_RS06090	COG0564	pseudouridine synthase activity
CO704_RS06100	COG1566	PFAM secretion protein HlyD family protein
CO704_RS06115	COG2207	Transcriptional regulator
CO704_RS06120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CO704_RS06145	COG1051	belongs to the nudix hydrolase family
CO704_RS06160	COG3122	Protein conserved in bacteria
CO704_RS06180	COG2116	formate transmembrane transporter activity
CO704_RS06185	COG4133	protoheme IX ABC transporter activity
CO704_RS06195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CO704_RS06200	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CO704_RS06210	COG1138	Cytochrome C-type biogenesis protein
CO704_RS06215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CO704_RS06220	COG3088	subunit of a heme lyase
CO704_RS06220	COG4235	cytochrome complex assembly
CO704_RS06245	COG2217	Heavy metal translocating P-type atpase
CO704_RS06250	COG2067	long-chain fatty acid transport protein
CO704_RS06260	COG3691	Protein conserved in bacteria
CO704_RS06275	COG2062	phosphohistidine phosphatase, SixA
CO704_RS06285	COG2890	protein-(glutamine-N5) methyltransferase activity
CO704_RS06300	COG0730	response to heat
CO704_RS06305	COG3101	peptidyl-lysine hydroxylation
CO704_RS06320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CO704_RS06340	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CO704_RS06350	COG0586	Pfam SNARE associated Golgi protein
CO704_RS06360	COG0285	dihydrofolate synthase activity
CO704_RS06365	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CO704_RS06370	COG1286	toxin biosynthetic process
CO704_RS06375	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CO704_RS06380	COG0163	prenyltransferase activity
CO704_RS06390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO704_RS06400	COG4160	amino acid transport
CO704_RS06405	COG4598	ABC transporter
CO704_RS06415	COG0246	Mannitol dehydrogenase
CO704_RS06420	COG1070	Carbohydrate kinase
CO704_RS06430	COG1090	epimerase
CO704_RS06435	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CO704_RS06440	COG0625	glutathione transferase activity
CO704_RS06445	COG0625	glutathione transferase activity
CO704_RS06450	COG0622	Phosphoesterase
CO704_RS06460	COG1609	Transcriptional regulator
CO704_RS06470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS06480	COG3037	sugar-specific permease SgaT UlaA
CO704_RS06485	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CO704_RS06490	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CO704_RS06515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CO704_RS06520	COG0490	domain, Protein
CO704_RS06520	COG0471	metal ion transport
CO704_RS06525	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CO704_RS06530	COG0436	Aminotransferase
CO704_RS06535	COG0583	DNA-binding transcription factor activity
CO704_RS06550	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CO704_RS06585	COG0839	Belongs to the complex I subunit 6 family
CO704_RS06590	COG0713	ATP synthesis coupled electron transport
CO704_RS06595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CO704_RS06600	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CO704_RS06620	COG2153	protein acetylation
CO704_RS06625	COG4575	ribosome binding
CO704_RS06630	COG1169	isochorismate synthase
CO704_RS06675	COG0247	lactate metabolic process
CO704_RS06680	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CO704_RS06685	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CO704_RS06690	COG2271	Major facilitator Superfamily
CO704_RS06695	COG0584	glycerophosphoryl diester phosphodiesterase
CO704_RS06700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CO704_RS06710	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CO704_RS06725	COG2205	protein histidine kinase activity
CO704_RS06725	COG0784	Response regulator, receiver
CO704_RS06730	COG2197	response regulator
CO704_RS06735	COG2198	Histidine kinase
CO704_RS06735	COG0642	Histidine kinase
CO704_RS06755	COG2169	Transcriptional regulator
CO704_RS06755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CO704_RS06765	COG4615	Cyclic peptide transporter
CO704_RS06770	COG2239	Acts as a magnesium transporter
CO704_RS06785	COG3082	Protein of unknown function (DUF1414)
CO704_RS06790	COG3081	Nucleoid-associated protein
CO704_RS06805	COG1061	Type III restriction enzyme res subunit
CO704_RS06810	COG1187	pseudouridine synthase activity
CO704_RS06815	COG2814	Major facilitator Superfamily
CO704_RS06825	COG4172	Belongs to the ABC transporter superfamily
CO704_RS06830	COG4239	(ABC) transporter, permease
CO704_RS06835	COG4174	ABC transporter (Permease)
CO704_RS06840	COG4166	transmembrane transport
CO704_RS06845	COG2200	EAL domain
CO704_RS06850	COG0791	NLP P60 protein
CO704_RS06860	COG0671	phosphoesterase, PA-phosphatase related
CO704_RS06865	COG0523	cobalamin synthesis protein
CO704_RS06870	COG0246	Mannitol dehydrogenase
CO704_RS06900	COG2814	Major facilitator Superfamily
CO704_RS06905	COG0583	DNA-binding transcription factor activity
CO704_RS06910	COG4221	oxidoreductase activity
CO704_RS06915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS06915	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS06920	COG1105	Belongs to the carbohydrate kinase PfkB family
CO704_RS06925	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CO704_RS06925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO704_RS06925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO704_RS06935	COG2855	membrane
CO704_RS06940	COG0583	DNA-binding transcription factor activity
CO704_RS06955	COG0765	amino acid transport
CO704_RS06960	COG1126	abc transporter atp-binding protein
CO704_RS06965	COG0833	amino acid
CO704_RS06975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CO704_RS06985	COG4771	TonB-dependent receptor
CO704_RS07000	COG2311	Membrane
CO704_RS07015	COG1129	ABC transporter
CO704_RS07060	COG2949	membrane
CO704_RS07070	COG1346	cytolysis
CO704_RS07080	COG1376	ErfK ybiS ycfS ynhG family protein
CO704_RS07085	COG0488	(ABC) transporter
CO704_RS07095	COG2271	Major facilitator Superfamily
CO704_RS07100	COG1609	Transcriptional regulator
CO704_RS07105	COG2239	Acts as a magnesium transporter
CO704_RS07115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CO704_RS07120	COG0303	'Molybdopterin
CO704_RS07155	COG3713	MltA-interacting MipA family protein
CO704_RS07170	COG2133	pyrroloquinoline quinone binding
CO704_RS07175	COG0625	glutathione transferase activity
CO704_RS07180	COG1686	Belongs to the peptidase S11 family
CO704_RS07185	COG1349	DNA-binding transcription factor activity
CO704_RS07190	COG0671	phosphoesterase, PA-phosphatase related
CO704_RS07200	COG2814	Major facilitator Superfamily
CO704_RS07210	COG0489	protein tyrosine kinase activity
CO704_RS07220	COG4807	Protein conserved in bacteria
CO704_RS07225	COG0657	acetylesterase activity
CO704_RS07230	COG0583	DNA-binding transcription factor activity
CO704_RS07235	COG0667	Aldo Keto reductase
CO704_RS07240	COG2814	Major facilitator Superfamily
CO704_RS07250	COG1609	Transcriptional regulator
CO704_RS07255	COG1263	PTS System
CO704_RS07255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO704_RS07260	COG2723	6-phospho-beta-galactosidase activity
CO704_RS07265	COG4772	TonB-dependent receptor
CO704_RS07305	COG0351	phosphomethylpyrimidine kinase
CO704_RS07310	COG2188	Transcriptional regulator
CO704_RS07315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO704_RS07320	COG1397	ADP-ribosylglycohydrolase
CO704_RS07325	COG2211	Major facilitator Superfamily
CO704_RS07335	COG1830	Aldolase
CO704_RS07345	COG1597	lipid kinase activity
CO704_RS07350	COG0826	peptidase U32
CO704_RS07360	COG0745	RESPONSE REGULATOR receiver
CO704_RS07365	COG2205	protein histidine kinase activity
CO704_RS07400	COG0443	Heat shock 70 kDa protein
CO704_RS07405	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CO704_RS07410	COG5001	Diguanylate cyclase
CO704_RS07410	COG3447	MASE1 domain protein
CO704_RS07410	COG5002	protein histidine kinase activity
CO704_RS07425	COG2982	Protein involved in outer membrane biogenesis
CO704_RS07445	COG0489	protein tyrosine kinase activity
CO704_RS07445	COG3206	protein involved in exopolysaccharide biosynthesis
CO704_RS07450	COG0463	Glycosyl transferase, family 2
CO704_RS07455	COG1045	serine acetyltransferase
CO704_RS07460	COG0438	transferase activity, transferring glycosyl groups
CO704_RS07470	COG1216	Glycosyl transferase, family 2
CO704_RS07475	COG0110	maltose O-acetyltransferase activity
CO704_RS07480	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CO704_RS07485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CO704_RS07490	COG1051	belongs to the nudix hydrolase family
CO704_RS07495	COG0297	glycogen (starch) synthase activity
CO704_RS07505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CO704_RS07510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CO704_RS07515	COG2244	polysaccharide biosynthetic process
CO704_RS07520	COG2327	Polysaccharide pyruvyl transferase
CO704_RS07525	COG0438	transferase activity, transferring glycosyl groups
CO704_RS07545	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CO704_RS07550	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CO704_RS07555	COG2089	acid synthase
CO704_RS07575	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CO704_RS07580	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS07610	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CO704_RS07645	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CO704_RS07650	COG1088	dTDP-glucose 4,6-dehydratase activity
CO704_RS07680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CO704_RS07695	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CO704_RS07700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CO704_RS07705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CO704_RS07710	COG0583	DNA-binding transcription factor activity
CO704_RS07715	COG0531	amino acid
CO704_RS07720	COG2925	Exonuclease
CO704_RS07735	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CO704_RS07745	COG1289	transmembrane transporter activity
CO704_RS07755	COG0640	Transcriptional regulator
CO704_RS07760	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CO704_RS07765	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CO704_RS07795	COG0813	purine-nucleoside phosphorylase activity
CO704_RS07805	COG4335	DNA alkylation repair
CO704_RS07830	COG0534	Mate efflux family protein
CO704_RS07835	COG0668	transmembrane transport
CO704_RS07840	COG1376	ErfK ybiS ycfS ynhG family protein
CO704_RS07855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CO704_RS07860	COG1012	belongs to the aldehyde dehydrogenase family
CO704_RS07865	COG1917	Cupin 2, conserved barrel domain protein
CO704_RS07865	COG1396	sequence-specific DNA binding
CO704_RS07870	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CO704_RS07875	COG0174	glutamine synthetase
CO704_RS07880	COG0531	amino acid
CO704_RS07890	COG0006	proline dipeptidase activity
CO704_RS07895	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CO704_RS07900	COG0840	transmembrane signaling receptor activity
CO704_RS07905	COG0583	DNA-binding transcription factor activity
CO704_RS07920	COG0778	Nitroreductase
CO704_RS07925	COG2771	luxR family
CO704_RS07950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CO704_RS07950	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CO704_RS07955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CO704_RS07970	COG0583	DNA-binding transcription factor activity
CO704_RS07975	COG0840	transmembrane signaling receptor activity
CO704_RS07980	COG0523	cobalamin synthesis protein
CO704_RS07985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CO704_RS07990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CO704_RS07995	COG1116	anion transmembrane transporter activity
CO704_RS08000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CO704_RS08005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CO704_RS08015	COG0789	Transcriptional regulator
CO704_RS08020	COG3272	Protein of unknown function (DUF1722)
CO704_RS08030	COG3423	Transcriptional regulator
CO704_RS08185	COG0582	viral genome integration into host DNA
CO704_RS08225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CO704_RS08240	COG2072	flavoprotein involved in K transport
CO704_RS08245	COG0583	DNA-binding transcription factor activity
CO704_RS08250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO704_RS08255	COG1126	abc transporter atp-binding protein
CO704_RS08265	COG1283	sodium-dependent phosphate transmembrane transporter activity
CO704_RS08295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO704_RS08300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO704_RS08305	COG0383	alpha-mannosidase activity
CO704_RS08310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS08310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS08310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CO704_RS08310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS08310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS08310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CO704_RS08325	COG1418	mRNA catabolic process
CO704_RS08335	COG3727	T/G mismatch-specific endonuclease activity
CO704_RS08340	COG0697	spore germination
CO704_RS08345	COG2354	Protein conserved in bacteria
CO704_RS08350	COG5475	Uncharacterized small protein (DUF2158)
CO704_RS08375	COG2197	response regulator
CO704_RS08385	COG1987	bacterial-type flagellum assembly
CO704_RS08415	COG3144	bacterial-type flagellum assembly
CO704_RS08420	COG2882	bacterial-type flagellum organization
CO704_RS08425	COG1157	protein secretion by the type III secretion system
CO704_RS08430	COG1317	bacterial-type flagellum organization
CO704_RS08435	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CO704_RS08450	COG1737	Transcriptional regulator
CO704_RS08455	COG0425	Belongs to the sulfur carrier protein TusA family
CO704_RS08460	COG2391	methyltransferase activity
CO704_RS08470	COG0366	Alpha amylase catalytic
CO704_RS08520	COG1191	sigma factor activity
CO704_RS08530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO704_RS08540	COG0765	amino acid transport
CO704_RS08545	COG1126	abc transporter atp-binding protein
CO704_RS08555	COG2197	response regulator
CO704_RS08565	COG2197	response regulator
CO704_RS08605	COG3772	lysozyme
CO704_RS08615	COG3012	SEC-C Motif Domain Protein
CO704_RS08615	COG3318	Belongs to the UPF0149 family
CO704_RS08620	COG1528	Iron-storage protein
CO704_RS08625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CO704_RS08645	COG0840	transmembrane signaling receptor activity
CO704_RS08655	COG0601	transmembrane transport
CO704_RS08660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CO704_RS08665	COG0444	Belongs to the ABC transporter superfamily
CO704_RS08670	COG4608	Belongs to the ABC transporter superfamily
CO704_RS08680	COG1528	Iron-storage protein
CO704_RS08715	COG0835	chemotaxis
CO704_RS08720	COG1301	dicarboxylic acid transport
CO704_RS08750	COG0840	transmembrane signaling receptor activity
CO704_RS08765	COG0745	RESPONSE REGULATOR receiver
CO704_RS08795	COG3102	Protein conserved in bacteria
CO704_RS08800	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CO704_RS08805	COG3142	Participates in the control of copper homeostasis
CO704_RS08825	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CO704_RS08830	COG1801	Protein of unknown function DUF72
CO704_RS08835	COG1335	isochorismatase
CO704_RS08845	COG0494	nUDIX hydrolase
CO704_RS08860	COG0632	four-way junction helicase activity
CO704_RS08870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CO704_RS08880	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CO704_RS08885	COG0739	heme binding
CO704_RS08890	COG1560	Kdo2-lipid A biosynthetic process
CO704_RS08895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CO704_RS08910	COG4106	trans-aconitate 2-methyltransferase activity
CO704_RS08930	COG1737	Transcriptional regulator
CO704_RS08935	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CO704_RS08940	COG0129	dihydroxy-acid dehydratase activity
CO704_RS08945	COG0800	Aldolase
CO704_RS08955	COG3141	response to X-ray
CO704_RS08960	COG2979	Protein of unknown function (DUF533)
CO704_RS08965	COG1770	oligopeptidase
CO704_RS08970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CO704_RS08975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CO704_RS08985	COG2372	response to copper ion
CO704_RS08990	COG1276	copper resistance
CO704_RS09000	COG0659	secondary active sulfate transmembrane transporter activity
CO704_RS09030	COG3008	intermembrane lipid transfer
CO704_RS09035	COG2995	paraquat-inducible protein a
CO704_RS09040	COG1956	GAF domain-containing protein
CO704_RS09045	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CO704_RS09050	COG0793	Belongs to the peptidase S41A family
CO704_RS09055	COG0501	Belongs to the peptidase M48B family
CO704_RS09060	COG2814	Major facilitator Superfamily
CO704_RS09065	COG1414	Transcriptional regulator
CO704_RS09100	COG0768	penicillin binding
CO704_RS09105	COG2226	methyltransferase
CO704_RS09125	COG3716	PTS system mannose fructose sorbose family IID component
CO704_RS09130	COG3715	PTS system
CO704_RS09135	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO704_RS09135	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS09140	COG1253	flavin adenine dinucleotide binding
CO704_RS09145	COG2200	EAL domain
CO704_RS09155	COG0583	DNA-binding transcription factor activity
CO704_RS09160	COG1760	l-serine dehydratase
CO704_RS09170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CO704_RS09180	COG0251	oxidation-reduction process
CO704_RS09185	COG1199	ATP-dependent helicase activity
CO704_RS09190	COG1214	PFAM Peptidase M22, glycoprotease
CO704_RS09195	COG3065	identical protein binding
CO704_RS09200	COG0318	PFAM AMP-dependent synthetase and ligase
CO704_RS09215	COG2894	cell division
CO704_RS09220	COG0850	regulation of cytokinetic process
CO704_RS09225	COG3100	YcgL domain-containing protein
CO704_RS09230	COG2951	lytic endotransglycosylase activity
CO704_RS09235	COG0179	Fumarylacetoacetate (FAA) hydrolase
CO704_RS09250	COG3042	response to heat
CO704_RS09270	COG2719	SpoVR family
CO704_RS09285	COG3263	regulation of cellular component size
CO704_RS09290	COG1619	proteins homologs of microcin C7 resistance protein MccF
CO704_RS09300	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CO704_RS09310	COG4774	siderophore transport
CO704_RS09355	COG0477	Major facilitator Superfamily
CO704_RS09375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CO704_RS09380	COG4977	sequence-specific DNA binding
CO704_RS09420	COG2986	histidine ammonia-lyase
CO704_RS09425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CO704_RS09430	COG1250	3-hydroxyacyl-CoA dehydrogenase
CO704_RS09435	COG1024	Enoyl-CoA hydratase
CO704_RS09445	COG2188	Transcriptional regulator
CO704_RS09485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CO704_RS09490	COG0583	DNA-binding transcription factor activity
CO704_RS09495	COG2814	Major facilitator Superfamily
CO704_RS09500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CO704_RS09505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CO704_RS09505	COG0473	3-isopropylmalate dehydrogenase activity
CO704_RS09605	COG0012	GTP binding
CO704_RS09625	COG0583	DNA-binding transcription factor activity
CO704_RS09630	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS09635	COG1942	4-Oxalocrotonate Tautomerase
CO704_RS09640	COG0659	secondary active sulfate transmembrane transporter activity
CO704_RS09670	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CO704_RS09695	COG0387	Pfam Sodium calcium exchanger
CO704_RS09700	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CO704_RS09710	COG0840	transmembrane signaling receptor activity
CO704_RS09715	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CO704_RS09720	COG4932	domain protein
CO704_RS09725	COG2197	response regulator
CO704_RS09730	COG3850	Histidine kinase
CO704_RS09735	COG2223	nitrite transmembrane transporter activity
CO704_RS09740	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CO704_RS09745	COG1140	nitrate reductase beta subunit
CO704_RS09750	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CO704_RS09755	COG2181	nitrate reductase activity
CO704_RS09765	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CO704_RS09770	COG1393	Belongs to the ArsC family
CO704_RS09775	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CO704_RS09810	COG0788	formyltetrahydrofolate deformylase activity
CO704_RS09820	COG1752	Esterase of the alpha-beta hydrolase superfamily
CO704_RS09825	COG0745	RESPONSE REGULATOR receiver
CO704_RS09830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CO704_RS09840	COG2916	Histone family protein nucleoid-structuring protein H-NS
CO704_RS09850	COG1454	alcohol dehydrogenase
CO704_RS09850	COG1012	belongs to the aldehyde dehydrogenase family
CO704_RS09855	COG2095	MarC family integral membrane protein
CO704_RS09865	COG0601	transmembrane transport
CO704_RS09870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CO704_RS09875	COG0444	Belongs to the ABC transporter superfamily
CO704_RS09880	COG4608	Belongs to the ABC transporter superfamily
CO704_RS09885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CO704_RS09925	COG2842	Transposition protein
CO704_RS10065	COG4383	Mu-like prophage protein gp29
CO704_RS10070	COG2369	cell adhesion
CO704_RS10090	COG4397	Mu-like prophage major head subunit gpT
CO704_RS10185	COG3706	GGDEF domain
CO704_RS10190	COG2200	EAL domain
CO704_RS10195	COG2350	Protein conserved in bacteria
CO704_RS10230	COG2917	probably involved in intracellular septation
CO704_RS10240	COG3047	cAMP biosynthetic process
CO704_RS10245	COG0159	tryptophan synthase activity
CO704_RS10260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CO704_RS10260	COG0512	Glutamine amidotransferase of anthranilate synthase
CO704_RS10265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CO704_RS10270	COG0613	PHP domain protein
CO704_RS10275	COG0009	L-threonylcarbamoyladenylate synthase
CO704_RS10280	COG0789	Transcriptional regulator
CO704_RS10285	COG1187	pseudouridine synthase activity
CO704_RS10290	COG2211	Major facilitator Superfamily
CO704_RS10295	COG1472	Belongs to the glycosyl hydrolase 3 family
CO704_RS10300	COG2207	Transcriptional regulator
CO704_RS10310	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS10315	COG0616	signal peptide processing
CO704_RS10340	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CO704_RS10350	COG0671	phosphoesterase, PA-phosphatase related
CO704_RS10355	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CO704_RS10360	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CO704_RS10370	COG0023	Translation Initiation Factor
CO704_RS10380	COG1349	DNA-binding transcription factor activity
CO704_RS10385	COG1882	Formate acetyltransferase
CO704_RS10390	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CO704_RS10415	COG1024	Enoyl-CoA hydratase
CO704_RS10420	COG5001	Diguanylate cyclase
CO704_RS10430	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CO704_RS10430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CO704_RS10440	COG4172	Belongs to the ABC transporter superfamily
CO704_RS10450	COG4171	peptide transport system, permease
CO704_RS10465	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CO704_RS10470	COG1842	Phage shock protein A
CO704_RS10480	COG1983	PspC domain protein
CO704_RS10490	COG3106	COG3106 Predicted ATPase
CO704_RS10505	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CO704_RS10510	COG4948	Mandelate Racemase Muconate Lactonizing
CO704_RS10515	COG2866	Carboxypeptidase
CO704_RS10520	COG4166	transmembrane transport
CO704_RS10525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CO704_RS10560	COG1505	serine-type exopeptidase activity
CO704_RS10570	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CO704_RS10575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CO704_RS10600	COG0513	Belongs to the DEAD box helicase family
CO704_RS10605	COG3781	membrane
CO704_RS10610	COG0840	transmembrane signaling receptor activity
CO704_RS10625	COG0488	(ABC) transporter
CO704_RS10675	COG0519	Catalyzes the synthesis of GMP from XMP
CO704_RS10675	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CO704_RS10680	COG0747	negative chemotaxis
CO704_RS10690	COG2084	Dehydrogenase
CO704_RS10725	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CO704_RS10740	COG2814	Major facilitator Superfamily
CO704_RS10745	COG0697	spore germination
CO704_RS10755	COG4977	sequence-specific DNA binding
CO704_RS10760	COG1846	Transcriptional regulator
CO704_RS10770	COG2814	Major facilitator Superfamily
CO704_RS10780	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS10785	COG0583	DNA-binding transcription factor activity
CO704_RS10790	COG1012	belongs to the aldehyde dehydrogenase family
CO704_RS10800	COG2066	Belongs to the glutaminase family
CO704_RS10805	COG2199	diguanylate cyclase activity
CO704_RS10820	COG2814	Major facilitator Superfamily
CO704_RS10825	COG0583	DNA-binding transcription factor activity
CO704_RS10840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CO704_RS10845	COG0454	-acetyltransferase
CO704_RS10855	COG0346	lactoylglutathione lyase activity
CO704_RS10865	COG2814	Major facilitator Superfamily
CO704_RS10875	COG2199	diguanylate cyclase activity
CO704_RS10910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CO704_RS10915	COG3192	ethanolamine utilization protein
CO704_RS10925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CO704_RS10935	COG0010	Belongs to the arginase family
CO704_RS10960	COG2233	PERMEase
CO704_RS10965	COG0493	'glutamate synthase
CO704_RS10965	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO704_RS10970	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO704_RS10975	COG0402	S-adenosylhomocysteine deaminase activity
CO704_RS10980	COG0493	'glutamate synthase
CO704_RS10980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO704_RS10985	COG2068	MobA-Related Protein
CO704_RS10990	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CO704_RS10995	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CO704_RS10995	COG3608	succinylglutamate desuccinylase aspartoacylase
CO704_RS11000	COG0549	Belongs to the carbamate kinase family
CO704_RS11010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CO704_RS11015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CO704_RS11020	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CO704_RS11025	COG3829	transcription factor binding
CO704_RS11035	COG3710	Transcriptional regulator
CO704_RS11045	COG2134	cdp-diacylglycerol pyrophosphatase
CO704_RS11050	COG0179	Fumarylacetoacetate (FAA) hydrolase
CO704_RS11060	COG0583	DNA-binding transcription factor activity
CO704_RS11070	COG0066	3-isopropylmalate dehydratase activity
CO704_RS11075	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CO704_RS11080	COG1649	PFAM Uncharacterised BCR, COG1649
CO704_RS11095	COG2249	NAD(P)H dehydrogenase (quinone) activity
CO704_RS11105	COG2070	2-Nitropropane dioxygenase
CO704_RS11115	COG0477	Major facilitator Superfamily
CO704_RS11125	COG2814	Major facilitator Superfamily
CO704_RS11130	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CO704_RS11145	COG0251	oxidation-reduction process
CO704_RS11175	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS11260	COG0583	DNA-binding transcription factor activity
CO704_RS11275	COG0814	amino acid
CO704_RS11295	COG1942	4-Oxalocrotonate Tautomerase
CO704_RS11315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CO704_RS11330	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CO704_RS11335	COG0625	glutathione transferase activity
CO704_RS11340	COG1609	Transcriptional regulator
CO704_RS11350	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS11370	COG2315	Protein conserved in bacteria
CO704_RS11375	COG0697	spore germination
CO704_RS11390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO704_RS11410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO704_RS11430	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CO704_RS11435	COG4772	TonB-dependent receptor
CO704_RS11455	COG2375	cellular response to nickel ion
CO704_RS11460	COG2841	Protein conserved in bacteria
CO704_RS11475	COG1252	NADH dehydrogenase
CO704_RS11480	COG1959	2 iron, 2 sulfur cluster binding
CO704_RS11490	COG0626	cystathionine gamma-synthase activity
CO704_RS11495	COG1802	Transcriptional regulator
CO704_RS11505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CO704_RS11510	COG0601	transmembrane transport
CO704_RS11570	COG1652	LysM domain
CO704_RS11575	COG1012	belongs to the aldehyde dehydrogenase family
CO704_RS11595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CO704_RS11600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CO704_RS11605	COG1653	transport
CO704_RS11615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CO704_RS11620	COG0395	ABC-type sugar transport system, permease component
CO704_RS11625	COG1175	transmembrane transport
CO704_RS11660	COG1609	Transcriptional regulator
CO704_RS11665	COG0483	inositol monophosphate 1-phosphatase activity
CO704_RS11685	COG1271	oxidase subunit
CO704_RS11690	COG1294	oxidase, subunit
CO704_RS11700	COG4783	chaperone-mediated protein folding
CO704_RS11705	COG1215	transferase activity, transferring glycosyl groups
CO704_RS11710	COG2076	Multidrug Resistance protein
CO704_RS11720	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CO704_RS11735	COG4166	transmembrane transport
CO704_RS11740	COG0601	transmembrane transport
CO704_RS11745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CO704_RS11755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CO704_RS11770	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CO704_RS11775	COG0183	Belongs to the thiolase family
CO704_RS11780	COG2050	protein possibly involved in aromatic compounds catabolism
CO704_RS11785	COG1250	3-hydroxyacyl-CoA dehydrogenase
CO704_RS11790	COG1024	Enoyl-CoA hydratase
CO704_RS11795	COG1024	Enoyl-CoA hydratase
CO704_RS11800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CO704_RS11805	COG2151	metal-sulfur cluster biosynthetic enzyme
CO704_RS11810	COG3396	Phenylacetate-CoA oxygenase
CO704_RS11815	COG3460	Phenylacetate-CoA oxygenase
CO704_RS11820	COG3396	Phenylacetate-CoA oxygenase
CO704_RS11825	COG1012	belongs to the aldehyde dehydrogenase family
CO704_RS11825	COG2030	dehydratase
CO704_RS11875	COG1012	belongs to the aldehyde dehydrogenase family
CO704_RS11880	COG2207	Transcriptional regulator
CO704_RS11885	COG3784	Protein of unknown function (DUF1318)
CO704_RS11895	COG2911	Protein conserved in bacteria
CO704_RS11900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CO704_RS11905	COG3187	Heat shock protein
CO704_RS11910	COG3042	response to heat
CO704_RS11915	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CO704_RS11915	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CO704_RS11915	COG1013	pyruvate-flavodoxin oxidoreductase activity
CO704_RS11915	COG0674	pyruvate-flavodoxin oxidoreductase activity
CO704_RS11950	COG5455	response to cobalt ion
CO704_RS11970	COG0514	ATP-dependent DNA helicase (RecQ)
CO704_RS11990	COG2207	Transcriptional regulator
CO704_RS12025	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CO704_RS12030	COG0339	signal peptide processing
CO704_RS12035	COG4221	oxidoreductase activity
CO704_RS12050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CO704_RS12095	COG0300	oxidoreductase activity
CO704_RS12110	COG1770	oligopeptidase
CO704_RS12130	COG3038	cytochrome b561
CO704_RS12135	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CO704_RS12145	COG4628	conserved protein (DUF2132)
CO704_RS12150	COG0840	transmembrane signaling receptor activity
CO704_RS12200	COG2932	Transcriptional regulator
CO704_RS12215	COG2842	Transposition protein
CO704_RS12340	COG4383	Mu-like prophage protein gp29
CO704_RS12345	COG2369	cell adhesion
CO704_RS12365	COG4397	Mu-like prophage major head subunit gpT
CO704_RS12500	COG4682	membrane
CO704_RS12535	COG3300	MHYT domain
CO704_RS12535	COG5001	Diguanylate cyclase
CO704_RS12555	COG4122	O-methyltransferase activity
CO704_RS12560	COG1643	Atp-dependent helicase
CO704_RS12570	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CO704_RS12575	COG3327	negative regulation of DNA-templated transcription, initiation
CO704_RS12610	COG0243	molybdopterin cofactor binding
CO704_RS12615	COG3381	protein complex oligomerization
CO704_RS12645	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CO704_RS12650	COG1940	carbohydrate kinase activity
CO704_RS12655	COG0583	DNA-binding transcription factor activity
CO704_RS12660	COG2814	Major facilitator Superfamily
CO704_RS12665	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CO704_RS12675	COG3591	Belongs to the peptidase S1B family
CO704_RS12680	COG0772	Belongs to the SEDS family
CO704_RS12685	COG0740	serine-type endopeptidase activity
CO704_RS12690	COG5001	Diguanylate cyclase
CO704_RS12705	COG0628	permease
CO704_RS12710	COG0400	carboxylic ester hydrolase activity
CO704_RS12725	COG3158	transport of potassium into the cell
CO704_RS12765	COG5295	Hep Hag repeat protein
CO704_RS12805	COG0386	Belongs to the glutathione peroxidase family
CO704_RS12810	COG0583	DNA-binding transcription factor activity
CO704_RS12840	COG3180	Ammonia monooxygenase
CO704_RS12850	COG1215	transferase activity, transferring glycosyl groups
CO704_RS12855	COG1649	PFAM Uncharacterised BCR, COG1649
CO704_RS12855	COG0726	polysaccharide deacetylase
CO704_RS12860	COG0457	Tetratricopeptide repeat
CO704_RS12880	COG3188	usher protein
CO704_RS12895	COG1966	Carbon starvation protein
CO704_RS12900	COG2879	small protein
CO704_RS12905	COG0523	cobalamin synthesis protein
CO704_RS12915	COG3275	phosphorelay sensor kinase activity
CO704_RS12920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CO704_RS12925	COG2011	ABC-type metal ion transport system permease component
CO704_RS12930	COG1464	Belongs to the NlpA lipoprotein family
CO704_RS12940	COG1902	pentaerythritol trinitrate reductase activity
CO704_RS12950	COG0583	DNA-binding transcription factor activity
CO704_RS12955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CO704_RS12965	COG2197	response regulator
CO704_RS12980	COG3188	usher protein
CO704_RS12990	COG3539	Fimbrial protein
CO704_RS12995	COG2197	response regulator
CO704_RS13000	COG2205	protein histidine kinase activity
CO704_RS13000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO704_RS13010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CO704_RS13015	COG2076	Multidrug Resistance protein
CO704_RS13020	COG2076	Multidrug Resistance protein
CO704_RS13025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CO704_RS13030	COG0726	polysaccharide deacetylase
CO704_RS13035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CO704_RS13035	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CO704_RS13040	COG0463	Glycosyl transferase, family 2
CO704_RS13045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CO704_RS13050	COG0826	peptidase U32
CO704_RS13055	COG1396	sequence-specific DNA binding
CO704_RS13060	COG3135	benzoate transporter
CO704_RS13065	COG2207	Transcriptional regulator
CO704_RS13090	COG1486	melibiose metabolic process
CO704_RS13095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CO704_RS13105	COG0747	negative chemotaxis
CO704_RS13110	COG2195	Cleaves the N-terminal amino acid of tripeptides
CO704_RS13115	COG0500	methyltransferase
CO704_RS13120	COG1275	C4-dicarboxylate transporter malic acid transport protein
CO704_RS13125	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CO704_RS13130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CO704_RS13145	COG0436	Aminotransferase
CO704_RS13150	COG0583	DNA-binding transcription factor activity
CO704_RS13160	COG5383	Protein conserved in bacteria
CO704_RS13165	COG0583	DNA-binding transcription factor activity
CO704_RS13170	COG2840	Smr protein MutS2
CO704_RS13175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CO704_RS13180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CO704_RS13190	COG0583	DNA-binding transcription factor activity
CO704_RS13195	COG0697	spore germination
CO704_RS13200	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CO704_RS13205	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CO704_RS13215	COG0531	amino acid
CO704_RS13225	COG0745	RESPONSE REGULATOR receiver
CO704_RS13240	COG2205	protein histidine kinase activity
CO704_RS13250	COG0114	fumarate hydratase activity
CO704_RS13255	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CO704_RS13255	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CO704_RS13265	COG5339	Protein conserved in bacteria
CO704_RS13285	COG1609	Transcriptional regulator
CO704_RS13290	COG1263	PTS System
CO704_RS13290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO704_RS13295	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CO704_RS13315	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CO704_RS13320	COG0385	Bile acid
CO704_RS13340	COG0673	inositol 2-dehydrogenase activity
CO704_RS13375	COG4659	FMN binding
CO704_RS13385	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CO704_RS13390	COG3104	oligopeptide transport
CO704_RS13395	COG0625	glutathione transferase activity
CO704_RS13415	COG3895	Periplasmic Protein
CO704_RS13420	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CO704_RS13430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO704_RS13435	COG1126	abc transporter atp-binding protein
CO704_RS13440	COG0765	amino acid transport
CO704_RS13450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO704_RS13455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CO704_RS13460	COG1473	amidohydrolase
CO704_RS13465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CO704_RS13480	COG1566	PFAM secretion protein HlyD family protein
CO704_RS13485	COG1289	transmembrane transporter activity
CO704_RS13490	COG4989	oxidoreductase activity
CO704_RS13495	COG3313	Fe-S protein
CO704_RS13505	COG1309	transcriptional regulator
CO704_RS13510	COG1902	pentaerythritol trinitrate reductase activity
CO704_RS13515	COG0346	lactoylglutathione lyase activity
CO704_RS13530	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CO704_RS13535	COG0791	NLP P60 protein
CO704_RS13540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CO704_RS13555	COG0583	DNA-binding transcription factor activity
CO704_RS13560	COG2814	Major facilitator Superfamily
CO704_RS13565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CO704_RS13570	COG2723	6-phospho-beta-galactosidase activity
CO704_RS13575	COG0307	riboflavin synthase, alpha
CO704_RS13600	COG0251	oxidation-reduction process
CO704_RS13610	COG0583	DNA-binding transcription factor activity
CO704_RS13630	COG1376	ErfK ybiS ycfS ynhG family protein
CO704_RS13635	COG2166	iron-sulfur cluster assembly
CO704_RS13645	COG0719	Fe-S assembly protein
CO704_RS13650	COG0396	ATPase activity
CO704_RS13655	COG0719	Fe-S assembly protein
CO704_RS13660	COG0316	Belongs to the HesB IscA family
CO704_RS13670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CO704_RS13680	COG2050	protein possibly involved in aromatic compounds catabolism
CO704_RS13685	COG0277	FAD linked oxidase domain protein
CO704_RS13685	COG0247	lactate metabolic process
CO704_RS13690	COG0628	permease
CO704_RS13700	COG2819	hydrolase of the alpha beta superfamily
CO704_RS13705	COG4774	siderophore transport
CO704_RS13715	COG0574	Belongs to the PEP-utilizing enzyme family
CO704_RS13715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CO704_RS13730	COG4256	Hemin uptake protein
CO704_RS13740	COG3720	iron ion transport
CO704_RS13745	COG4558	Periplasmic binding protein
CO704_RS13750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CO704_RS13755	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CO704_RS13770	COG1609	Transcriptional regulator
CO704_RS13775	COG0791	NLP P60 protein
CO704_RS13785	COG0386	Belongs to the glutathione peroxidase family
CO704_RS13795	COG0456	acetyltransferase
CO704_RS13795	COG1846	Transcriptional regulator
CO704_RS13805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CO704_RS13805	COG0072	phenylalanine-tRNA ligase activity
CO704_RS13820	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CO704_RS13825	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CO704_RS13840	COG3137	Salt-induced outer membrane protein
CO704_RS13845	COG1105	Belongs to the carbohydrate kinase PfkB family
CO704_RS13855	COG3001	Fructosamine kinase
CO704_RS13865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CO704_RS13870	COG1988	membrane-bound metal-dependent
CO704_RS13875	COG1823	symporter activity
CO704_RS13885	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CO704_RS13900	COG0322	excinuclease ABC activity
CO704_RS13905	COG2986	histidine ammonia-lyase
CO704_RS13915	COG3678	ATP-independent chaperone mediated protein folding
CO704_RS13930	COG1012	belongs to the aldehyde dehydrogenase family
CO704_RS13935	COG3138	arginine N-succinyltransferase
CO704_RS13945	COG0708	Exodeoxyribonuclease III
CO704_RS13955	COG1764	response to oxidative stress
CO704_RS13965	COG4134	Bacterial extracellular solute-binding protein
CO704_RS13970	COG4135	transport system, permease component
CO704_RS13975	COG4136	ATPase activity
CO704_RS13980	COG2897	thiosulfate sulfurtransferase activity
CO704_RS13985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CO704_RS13990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CO704_RS13995	COG0494	nUDIX hydrolase
CO704_RS14005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CO704_RS14020	COG0778	Nitroreductase
CO704_RS14025	COG0616	signal peptide processing
CO704_RS14030	COG0252	asparaginase activity
CO704_RS14035	COG1335	isochorismatase
CO704_RS14045	COG3139	Protein of unknown function (DUF1315)
CO704_RS14055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CO704_RS14065	COG3713	MltA-interacting MipA family protein
CO704_RS14070	COG2766	serine protein kinase
CO704_RS14080	COG0789	Transcriptional regulator
CO704_RS14105	COG0454	-acetyltransferase
CO704_RS14115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CO704_RS14120	COG2707	UPF0756 membrane protein
CO704_RS14125	COG0765	amino acid transport
CO704_RS14130	COG4597	amino acid ABC transporter
CO704_RS14140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO704_RS14145	COG0840	transmembrane signaling receptor activity
CO704_RS14150	COG2207	Transcriptional regulator
CO704_RS14155	COG2807	transmembrane transport
CO704_RS14160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CO704_RS14165	COG0504	CTP synthase activity
CO704_RS14175	COG3189	MarR family transcriptional regulator
CO704_RS14200	COG0401	homolog of Blt101
CO704_RS14255	COG0538	isocitrate dehydrogenase activity
CO704_RS14260	COG1187	pseudouridine synthase activity
CO704_RS14280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CO704_RS14285	COG0745	RESPONSE REGULATOR receiver
CO704_RS14295	COG2850	peptidyl-arginine hydroxylation
CO704_RS14300	COG3842	ATPase activity
CO704_RS14305	COG0395	ABC-type sugar transport system, permease component
CO704_RS14310	COG1840	ABC-type Fe3 transport system, periplasmic component
CO704_RS14315	COG3264	Mechanosensitive ion channel
CO704_RS14315	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CO704_RS14390	COG4591	ABC-type transport system involved in lipoprotein release permease component
CO704_RS14400	COG4591	ABC-type transport system involved in lipoprotein release permease component
CO704_RS14405	COG4763	Acyl-transferase
CO704_RS14410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CO704_RS14415	COG1376	ErfK ybiS ycfS ynhG family protein
CO704_RS14415	COG1388	LysM domain
CO704_RS14425	COG1309	transcriptional regulator
CO704_RS14470	COG3134	Outer membrane lipoprotein
CO704_RS14475	COG1252	NADH dehydrogenase
CO704_RS14500	COG5633	Lipoprotein
CO704_RS14505	COG0537	adenosine 5'-monophosphoramidase activity
CO704_RS14510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO704_RS14510	COG1263	PTS System
CO704_RS14515	COG0084	hydrolase, TatD family'
CO704_RS14520	COG0470	DNA polymerase III
CO704_RS14530	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CO704_RS14535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CO704_RS14540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CO704_RS14545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CO704_RS14550	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS14555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CO704_RS14570	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CO704_RS14575	COG1399	metal-binding, possibly nucleic acid-binding protein
CO704_RS14595	COG1530	ribonuclease E activity
CO704_RS14600	COG3615	Tellurite resistance protein tehB
CO704_RS14605	COG3615	Tellurite resistance protein tehB
CO704_RS14620	COG1256	bacterial-type flagellum assembly
CO704_RS14640	COG4786	Flagellar basal body rod
CO704_RS14650	COG1749	Flagellar hook protein flgE
CO704_RS14660	COG1558	bacterial-type flagellum-dependent cell motility
CO704_RS14665	COG1815	bacterial-type flagellum-dependent cell motility
CO704_RS14690	COG0728	peptidoglycan biosynthetic process
CO704_RS14705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CO704_RS14745	COG3038	cytochrome b561
CO704_RS14750	COG2353	YceI-like domain
CO704_RS14760	COG1560	Kdo2-lipid A biosynthetic process
CO704_RS14775	COG5645	(Lipo)protein
CO704_RS14780	COG2943	transferase activity, transferring hexosyl groups
CO704_RS14795	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CO704_RS14805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CO704_RS14810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CO704_RS14840	COG2197	response regulator
CO704_RS14865	COG3381	protein complex oligomerization
CO704_RS14875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CO704_RS14925	COG3394	polysaccharide catabolic process
CO704_RS14930	COG1486	melibiose metabolic process
CO704_RS14935	COG2169	Transcriptional regulator
CO704_RS14935	COG1917	Cupin 2, conserved barrel domain protein
CO704_RS14940	COG1447	Phosphotransferase system cellobiose-specific component IIA
CO704_RS14945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CO704_RS14950	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CO704_RS14955	COG1702	phosphate starvation-inducible protein PhoH
CO704_RS14970	COG2822	iron ion transport
CO704_RS14980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CO704_RS14985	COG0506	proline dehydrogenase activity
CO704_RS14985	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CO704_RS14985	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CO704_RS14990	COG3755	Protein conserved in bacteria
CO704_RS14995	COG1309	transcriptional regulator
CO704_RS15020	COG3729	General stress protein
CO704_RS15055	COG4221	oxidoreductase activity
CO704_RS15060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CO704_RS15065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CO704_RS15100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CO704_RS15110	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO704_RS15115	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO704_RS15120	COG1129	ABC transporter
CO704_RS15135	COG0583	DNA-binding transcription factor activity
CO704_RS15140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CO704_RS15145	COG2205	protein histidine kinase activity
CO704_RS15150	COG0745	RESPONSE REGULATOR receiver
CO704_RS15165	COG0582	viral genome integration into host DNA
CO704_RS15190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CO704_RS15270	COG3311	Transcriptional regulator
CO704_RS15275	COG2336	PFAM SpoVT AbrB
CO704_RS15280	COG2337	Toxic component of a toxin-antitoxin (TA) module
CO704_RS15310	COG0670	Belongs to the BI1 family
CO704_RS15315	COG2920	part of a sulfur-relay system
CO704_RS15320	COG1254	Belongs to the acylphosphatase family
CO704_RS15325	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CO704_RS15335	COG1832	CoA-binding protein
CO704_RS15340	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CO704_RS15350	COG0210	DNA helicase
CO704_RS15355	COG3304	Inner membrane component domain
CO704_RS15360	COG1289	transmembrane transporter activity
CO704_RS15365	COG3070	regulator of competence-specific genes
CO704_RS15385	COG1067	ATP-dependent peptidase activity
CO704_RS15400	COG1175	transmembrane transport
CO704_RS15405	COG3842	ATPase activity
CO704_RS15410	COG3130	regulation of translation
CO704_RS15415	COG3009	Protein conserved in bacteria
CO704_RS15420	COG3008	intermembrane lipid transfer
CO704_RS15420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CO704_RS15425	COG2995	paraquat-inducible protein a
CO704_RS15430	COG0488	(ABC) transporter
CO704_RS15440	COG3217	Mosc domain protein beta barrel domain protein
CO704_RS15440	COG0633	Ferredoxin
CO704_RS15455	COG0431	NADPH-dependent FMN reductase
CO704_RS15460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CO704_RS15465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CO704_RS15470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CO704_RS15480	COG0308	aminopeptidase N
CO704_RS15500	COG1448	Aminotransferase
CO704_RS15505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CO704_RS15510	COG3108	Peptidase M15
CO704_RS15515	COG2989	Protein conserved in bacteria
CO704_RS15525	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CO704_RS15535	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CO704_RS15540	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CO704_RS15545	COG3173	Aminoglycoside phosphotransferase
CO704_RS15560	COG3214	Protein conserved in bacteria
CO704_RS15575	COG2333	competence protein COMEC
CO704_RS15575	COG0658	competence protein
CO704_RS15580	COG0776	regulation of translation
CO704_RS15585	COG0539	negative regulation of cytoplasmic translation
CO704_RS15605	COG1944	ATP diphosphatase activity
CO704_RS15610	COG2116	formate transmembrane transporter activity
CO704_RS15615	COG1882	Formate acetyltransferase
CO704_RS15620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CO704_RS15625	COG0477	Major facilitator Superfamily
CO704_RS15630	COG3302	dmso reductase anchor subunit
CO704_RS15635	COG0437	4 iron, 4 sulfur cluster binding
CO704_RS15640	COG0243	molybdopterin cofactor binding
CO704_RS15650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CO704_RS15660	COG1674	ftsk spoiiie
CO704_RS15660	COG1178	ABC-type Fe3 transport system permease component
CO704_RS15680	COG0492	ferredoxin-NADP+ reductase activity
CO704_RS15685	COG4988	ABC transporter
CO704_RS15690	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CO704_RS15705	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CO704_RS15710	COG0542	response to heat
CO704_RS15720	COG1278	Cold shock
CO704_RS15730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO704_RS15735	COG2990	Protein conserved in bacteria
CO704_RS15740	COG3593	DNA synthesis involved in DNA repair
CO704_RS15745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CO704_RS15750	COG2431	L-lysine efflux transmembrane transporter activity
CO704_RS15755	COG1151	hydroxylamine reductase activity
CO704_RS15760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CO704_RS15770	COG0028	Belongs to the TPP enzyme family
CO704_RS15775	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CO704_RS15780	COG0702	epimerase
CO704_RS15785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CO704_RS15790	COG3023	N-Acetylmuramoyl-L-alanine amidase
CO704_RS15805	COG1126	abc transporter atp-binding protein
CO704_RS15810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO704_RS15815	COG4215	(ABC) transporter
CO704_RS15820	COG4160	amino acid transport
CO704_RS15825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO704_RS15830	COG2188	Transcriptional regulator
CO704_RS15845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CO704_RS15855	COG1177	transmembrane transport
CO704_RS15860	COG1176	ABC-type spermidine putrescine transport system, permease component I
CO704_RS15865	COG3842	ATPase activity
CO704_RS15870	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CO704_RS15915	COG3226	Transcriptional regulator
CO704_RS15920	COG0738	Major facilitator superfamily
CO704_RS15925	COG0561	phosphatase activity
CO704_RS15935	COG0667	Aldo Keto reductase
CO704_RS15940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CO704_RS15945	COG1321	iron dependent repressor
CO704_RS15955	COG2194	sulfuric ester hydrolase activity
CO704_RS15960	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CO704_RS15975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO704_RS15980	COG0765	amino acid transport
CO704_RS15985	COG1126	abc transporter atp-binding protein
CO704_RS15990	COG0668	transmembrane transport
CO704_RS16000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CO704_RS16010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CO704_RS16015	COG1446	asparaginase
CO704_RS16020	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CO704_RS16035	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CO704_RS16065	COG2197	response regulator
CO704_RS16070	COG3851	Histidine kinase
CO704_RS16095	COG1157	protein secretion by the type III secretion system
CO704_RS16120	COG4794	Type iii secretion
CO704_RS16130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CO704_RS16215	COG2850	peptidyl-arginine hydroxylation
CO704_RS16220	COG0789	Transcriptional regulator
CO704_RS16225	COG1174	glycine betaine transport
CO704_RS16230	COG1125	glycine betaine transport
CO704_RS16235	COG1174	glycine betaine transport
CO704_RS16240	COG1732	Glycine betaine
CO704_RS16245	COG0174	glutamine synthetase
CO704_RS16275	COG0285	dihydrofolate synthase activity
CO704_RS16285	COG1472	Belongs to the glycosyl hydrolase 3 family
CO704_RS16290	COG0277	FAD linked oxidase domain protein
CO704_RS16300	COG1686	Belongs to the peptidase S11 family
CO704_RS16310	COG0586	Pfam SNARE associated Golgi protein
CO704_RS16345	COG2723	6-phospho-beta-galactosidase activity
CO704_RS16360	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CO704_RS16370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CO704_RS16375	COG0513	Belongs to the DEAD box helicase family
CO704_RS16380	COG1309	transcriptional regulator
CO704_RS16385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO704_RS16390	COG1131	(ABC) transporter
CO704_RS16395	COG0842	Transport permease protein
CO704_RS16400	COG0842	Transport permease protein
CO704_RS16410	COG0670	Belongs to the BI1 family
CO704_RS16415	COG0314	molybdopterin synthase activity
CO704_RS16420	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CO704_RS16430	COG0521	Mo-molybdopterin cofactor biosynthetic process
CO704_RS16465	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CO704_RS16485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CO704_RS16495	COG4677	pectinesterase activity
CO704_RS16505	COG0561	phosphatase activity
CO704_RS16510	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CO704_RS16515	COG4149	molybdate abc transporter
CO704_RS16520	COG0725	ABC transporter, periplasmic molybdate-binding protein
CO704_RS16530	COG2005	Transcriptional regulator
CO704_RS16530	COG3585	molybdate ion transport
CO704_RS16535	COG1119	ATPase activity
CO704_RS16540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CO704_RS16545	COG1085	galactose-1-phosphate uridylyltransferase
CO704_RS16555	COG2017	converts alpha-aldose to the beta-anomer
CO704_RS16560	COG0588	phosphoglycerate mutase activity
CO704_RS16565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CO704_RS16575	COG1230	cation diffusion facilitator family transporter
CO704_RS16605	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CO704_RS16610	COG2885	chlorophyll binding
CO704_RS16620	COG3064	Membrane
CO704_RS16620	COG3064	Membrane
CO704_RS16625	COG0848	biopolymer transport protein
CO704_RS16630	COG0811	peptide transport
CO704_RS16635	COG0824	Thioesterase
CO704_RS16640	COG3790	cyd operon protein YbgE
CO704_RS16645	COG4890	Cyd operon protein YbgT
CO704_RS16650	COG1294	oxidase, subunit
CO704_RS16655	COG1271	oxidase subunit
CO704_RS16660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CO704_RS16670	COG0508	dehydrogenase complex catalyzes the overall conversion of
CO704_RS16675	COG0567	Dehydrogenase, E1 component
CO704_RS16680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CO704_RS16685	COG1053	succinate dehydrogenase
CO704_RS16690	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CO704_RS16695	COG2009	succinate dehydrogenase
CO704_RS16705	COG0372	Belongs to the citrate synthase family
CO704_RS16715	COG1984	allophanate hydrolase subunit 2
CO704_RS16720	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CO704_RS16725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CO704_RS16730	COG0415	Belongs to the DNA photolyase family
CO704_RS16750	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CO704_RS16760	COG2205	protein histidine kinase activity
CO704_RS16765	COG0745	RESPONSE REGULATOR receiver
CO704_RS16775	COG1982	Orn Lys Arg decarboxylase major
CO704_RS16795	COG2842	Transposition protein
CO704_RS16915	COG4383	Mu-like prophage protein gp29
CO704_RS16920	COG2369	cell adhesion
CO704_RS16940	COG4397	Mu-like prophage major head subunit gpT
CO704_RS17040	COG0531	amino acid
CO704_RS17045	COG0033	Phosphoglucomutase
CO704_RS17050	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CO704_RS17055	COG0596	Alpha beta hydrolase
CO704_RS17070	COG0735	belongs to the Fur family
CO704_RS17090	COG1263	PTS System
CO704_RS17090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO704_RS17090	COG2190	(PTS) system
CO704_RS17095	COG0363	glucosamine-6-phosphate deaminase activity
CO704_RS17100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CO704_RS17105	COG1846	Transcriptional regulator
CO704_RS17105	COG1940	carbohydrate kinase activity
CO704_RS17110	COG0647	UMP catabolic process
CO704_RS17115	COG0367	asparagine synthase
CO704_RS17155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CO704_RS17165	COG1702	phosphate starvation-inducible protein PhoH
CO704_RS17170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CO704_RS17180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CO704_RS17190	COG0765	amino acid transport
CO704_RS17195	COG0765	amino acid transport
CO704_RS17200	COG1126	abc transporter atp-binding protein
CO704_RS17205	COG2888	peptidyl-tyrosine sulfation
CO704_RS17220	COG1466	dna polymerase III delta subunit
CO704_RS17230	COG0799	negative regulation of ribosome biogenesis
CO704_RS17235	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CO704_RS17240	COG0768	penicillin binding
CO704_RS17245	COG0772	Belongs to the SEDS family
CO704_RS17250	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CO704_RS17260	COG1686	Belongs to the peptidase S11 family
CO704_RS17275	COG0583	DNA-binding transcription factor activity
CO704_RS17290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CO704_RS17295	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CO704_RS17310	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CO704_RS17315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO704_RS17335	COG3069	C4-dicarboxylate transmembrane transporter activity
CO704_RS17340	COG3719	Belongs to the RNase T2 family
CO704_RS17345	COG2610	gluconate transmembrane transporter activity
CO704_RS17350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CO704_RS17355	COG0791	NLP P60 protein
CO704_RS17365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CO704_RS17370	COG1191	sigma factor activity
CO704_RS17395	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CO704_RS17400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CO704_RS17405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CO704_RS17450	COG1706	bacterial-type flagellum-dependent cell motility
CO704_RS17460	COG4786	Flagellar basal body rod
CO704_RS17480	COG1558	bacterial-type flagellum-dependent cell motility
CO704_RS17485	COG1815	bacterial-type flagellum-dependent cell motility
CO704_RS17530	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CO704_RS17540	COG1677	Flagellar hook-basal body complex protein FliE
CO704_RS17565	COG1987	bacterial-type flagellum assembly
CO704_RS17570	COG1684	flagellar biosynthetic protein fliR
CO704_RS17590	COG1609	Transcriptional regulator
CO704_RS17595	COG2190	(PTS) system
CO704_RS17595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO704_RS17595	COG1263	PTS System
CO704_RS17600	COG2501	S4 domain
CO704_RS17615	COG0582	viral genome integration into host DNA
CO704_RS17810	COG2733	membrane
CO704_RS17820	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS17825	COG0589	response to stress
CO704_RS17830	COG0402	S-adenosylhomocysteine deaminase activity
CO704_RS17835	COG0666	response to abiotic stimulus
CO704_RS17840	COG0583	DNA-binding transcription factor activity
CO704_RS17855	COG0596	Alpha beta hydrolase
CO704_RS17870	COG3383	formate dehydrogenase (NAD+) activity
CO704_RS17870	COG0243	molybdopterin cofactor binding
CO704_RS17875	COG0243	molybdopterin cofactor binding
CO704_RS17875	COG3383	formate dehydrogenase (NAD+) activity
CO704_RS17880	COG0437	4 iron, 4 sulfur cluster binding
CO704_RS17885	COG2864	formate dehydrogenase
CO704_RS17905	COG3220	belongs to the UPF0276 family
CO704_RS17950	COG1203	CRISPR-associated helicase, Cas3
CO704_RS17955	COG1518	maintenance of DNA repeat elements
CO704_RS17960	COG3041	Addiction module toxin RelE StbE family
CO704_RS17965	COG3077	Addiction module antitoxin, RelB DinJ family
CO704_RS17980	COG4221	oxidoreductase activity
CO704_RS17990	COG2186	Transcriptional regulator
CO704_RS18005	COG0440	acetolactate synthase activity
CO704_RS18010	COG0028	Belongs to the TPP enzyme family
CO704_RS18015	COG2879	small protein
CO704_RS18020	COG1966	Carbon starvation protein
CO704_RS18025	COG4771	TonB-dependent receptor
CO704_RS18035	COG0456	acetyltransferase
CO704_RS18040	COG2364	Membrane
CO704_RS18045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CO704_RS18060	COG1522	sequence-specific DNA binding
CO704_RS18065	COG0697	spore germination
CO704_RS18070	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CO704_RS18075	COG1924	4 iron, 4 sulfur cluster binding
CO704_RS18090	COG3695	enzyme binding
CO704_RS18095	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CO704_RS18100	COG1946	Acyl-CoA thioesterase
CO704_RS18105	COG0004	ammonium transporteR
CO704_RS18110	COG0347	Belongs to the P(II) protein family
CO704_RS18115	COG1132	(ABC) transporter
CO704_RS18120	COG1132	(ABC) transporter
CO704_RS18125	COG1522	sequence-specific DNA binding
CO704_RS18135	COG0561	phosphatase activity
CO704_RS18140	COG4533	DNA binding
CO704_RS18150	COG0824	Thioesterase
CO704_RS18155	COG1555	photosystem II stabilization
CO704_RS18160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CO704_RS18165	COG0776	regulation of translation
CO704_RS18170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CO704_RS18190	COG0271	Belongs to the BolA IbaG family
CO704_RS18195	COG3056	Lipoprotein
CO704_RS18200	COG2223	nitrite transmembrane transporter activity
CO704_RS18205	COG1053	succinate dehydrogenase
CO704_RS18215	COG2214	Heat shock protein DnaJ domain protein
CO704_RS18220	COG0443	Heat shock 70 kDa protein
CO704_RS18225	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CO704_RS18230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CO704_RS18235	COG1845	cytochrome c oxidase, subunit III
CO704_RS18240	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CO704_RS18250	COG2814	Major facilitator Superfamily
CO704_RS18260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CO704_RS18280	COG0142	geranyltranstransferase activity
CO704_RS18290	COG0667	Aldo Keto reductase
CO704_RS18295	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CO704_RS18300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CO704_RS18310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CO704_RS18310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CO704_RS18320	COG4238	major outer membrane lipoprotein
CO704_RS18325	COG3248	Nucleoside-binding outer membrane protein
CO704_RS18340	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CO704_RS18350	COG1862	Preprotein translocase
CO704_RS18360	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CO704_RS18370	COG0450	alkyl hydroperoxide reductase
CO704_RS18375	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CO704_RS18385	COG1335	isochorismatase
CO704_RS18390	COG0583	DNA-binding transcription factor activity
CO704_RS18395	COG0366	Alpha amylase catalytic
CO704_RS18405	COG1114	Component of the transport system for branched-chain amino acids
CO704_RS18410	COG5002	protein histidine kinase activity
CO704_RS18420	COG0420	3'-5' exonuclease activity
CO704_RS18425	COG0419	ATPase involved in DNA repair
CO704_RS18435	COG1940	carbohydrate kinase activity
CO704_RS18440	COG2974	May be involved in recombination
CO704_RS18450	COG4126	flavin adenine dinucleotide binding
CO704_RS18465	COG3416	Protein conserved in bacteria
CO704_RS18470	COG1671	Belongs to the UPF0178 family
CO704_RS18475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CO704_RS18485	COG1785	Belongs to the alkaline phosphatase family
CO704_RS18495	COG2814	Major facilitator Superfamily
CO704_RS18500	COG1181	Belongs to the D-alanine--D-alanine ligase family
CO704_RS18520	COG0583	DNA-binding transcription factor activity
CO704_RS18530	COG1846	Transcriptional regulator
CO704_RS18535	COG1566	PFAM secretion protein HlyD family protein
CO704_RS18540	COG2814	Major facilitator Superfamily
CO704_RS18545	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CO704_RS18550	COG1335	isochorismatase
CO704_RS18555	COG1560	Kdo2-lipid A biosynthetic process
CO704_RS18560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CO704_RS18565	COG2203	Gaf domain
CO704_RS18565	COG2199	diguanylate cyclase activity
CO704_RS18570	COG0697	spore germination
CO704_RS18575	COG0840	transmembrane signaling receptor activity
CO704_RS18580	COG1113	amino acid transport
CO704_RS18585	COG0747	negative chemotaxis
CO704_RS18600	COG0444	Belongs to the ABC transporter superfamily
CO704_RS18605	COG4608	Belongs to the ABC transporter superfamily
CO704_RS18615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CO704_RS18620	COG4607	ABC-type enterochelin transport system periplasmic component
CO704_RS18625	COG4774	siderophore transport
CO704_RS18635	COG3290	protein histidine kinase activity
CO704_RS18640	COG4565	transcriptional regulatory protein
CO704_RS18660	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CO704_RS18660	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CO704_RS18665	COG4191	Histidine kinase
CO704_RS18670	COG4566	intracellular signal transduction
CO704_RS18685	COG3443	Belongs to the bacterial solute-binding protein 9 family
CO704_RS18710	COG1696	Membrane protein involved in D-alanine export
CO704_RS18715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CO704_RS18730	COG3539	Fimbrial protein
CO704_RS18735	COG3539	Fimbrial protein
CO704_RS18740	COG3539	Fimbrial protein
CO704_RS18745	COG3188	usher protein
CO704_RS18750	COG3121	Chaperone
CO704_RS18755	COG3539	Fimbrial protein
CO704_RS18770	COG0583	DNA-binding transcription factor activity
CO704_RS18780	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS18835	COG3223	Belongs to the PsiE family
CO704_RS18845	COG3093	addiction module antidote protein HigA
CO704_RS18880	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CO704_RS18885	COG2003	Belongs to the UPF0758 family
CO704_RS18940	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CO704_RS18950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CO704_RS18970	COG2195	Cleaves the N-terminal amino acid of tripeptides
CO704_RS18980	COG3034	peptidoglycan biosynthetic process
CO704_RS18985	COG0121	glutamine amidotransferase
CO704_RS18995	COG1960	acyl-CoA dehydrogenase activity
CO704_RS19000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CO704_RS19010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CO704_RS19050	COG2186	Transcriptional regulator
CO704_RS19055	COG1953	Uracil, thiamine, allantoin
CO704_RS19070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CO704_RS19075	COG0328	RNA-DNA hybrid ribonuclease activity
CO704_RS19080	COG2226	methyltransferase
CO704_RS19090	COG0741	lytic transglycosylase activity
CO704_RS19090	COG1388	LysM domain
CO704_RS19095	COG2226	methyltransferase
CO704_RS19105	COG2814	Major facilitator Superfamily
CO704_RS19110	COG0583	DNA-binding transcription factor activity
CO704_RS19115	COG0656	L-ascorbic acid biosynthetic process
CO704_RS19145	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CO704_RS19150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CO704_RS19155	COG2011	ABC-type metal ion transport system permease component
CO704_RS19160	COG1464	Belongs to the NlpA lipoprotein family
CO704_RS19170	COG1720	tRNA m6t6A37 methyltransferase activity
CO704_RS19185	COG3015	lipoprotein NlpE involved in copper resistance
CO704_RS19190	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CO704_RS19205	COG4568	rho-dependent transcription termination
CO704_RS19215	COG0037	tRNA processing
CO704_RS19220	COG0346	lactoylglutathione lyase activity
CO704_RS19225	COG1982	Orn Lys Arg decarboxylase major
CO704_RS19240	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CO704_RS19245	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CO704_RS19255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CO704_RS19260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CO704_RS19275	COG0750	zinc metalloprotease
CO704_RS19280	COG0575	Belongs to the CDS family
CO704_RS19285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CO704_RS19290	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CO704_RS19295	COG0233	cytoplasmic translational termination
CO704_RS19305	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CO704_RS19355	COG2860	membrane
CO704_RS19360	COG0316	Belongs to the HesB IscA family
CO704_RS19375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CO704_RS19380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CO704_RS19385	COG1120	ATPase activity
CO704_RS19390	COG4774	siderophore transport
CO704_RS19395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CO704_RS19400	COG1643	Atp-dependent helicase
CO704_RS19405	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CO704_RS19430	COG0617	tRNA 3'-terminal CCA addition
CO704_RS19435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CO704_RS19455	COG0726	polysaccharide deacetylase
CO704_RS19460	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS19465	COG0842	Transport permease protein
CO704_RS19470	COG1131	(ABC) transporter
CO704_RS19475	COG0288	reversible hydration of carbon dioxide
CO704_RS19480	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CO704_RS19485	COG4993	Dehydrogenase
CO704_RS19490	COG2132	Multicopper oxidase
CO704_RS19515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CO704_RS19520	COG0508	dehydrogenase complex catalyzes the overall conversion of
CO704_RS19525	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CO704_RS19540	COG3725	Membrane protein required for beta-lactamase induction
CO704_RS19555	COG4969	Belongs to the N-Me-Phe pilin family
CO704_RS19560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CO704_RS19565	COG1459	type II secretion system
CO704_RS19590	COG0494	nUDIX hydrolase
CO704_RS19615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CO704_RS19620	COG0849	cell division
CO704_RS19645	COG0772	Belongs to the SEDS family
CO704_RS19660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CO704_RS19670	COG0768	penicillin binding
CO704_RS19700	COG0028	Belongs to the TPP enzyme family
CO704_RS19705	COG0583	DNA-binding transcription factor activity
CO704_RS19730	COG2814	Major facilitator Superfamily
CO704_RS19750	COG1178	ABC-type Fe3 transport system permease component
CO704_RS19760	COG0586	Pfam SNARE associated Golgi protein
CO704_RS19765	COG0417	DNA replication proofreading
CO704_RS19775	COG0564	pseudouridine synthase activity
CO704_RS19780	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CO704_RS19805	COG2967	ApaG domain
CO704_RS19810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CO704_RS19820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CO704_RS19820	COG0475	glutathione-regulated potassium exporter activity
CO704_RS19835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CO704_RS19840	COG0505	Belongs to the CarA family
CO704_RS19870	COG1047	Peptidyl-prolyl cis-trans
CO704_RS19885	COG0196	riboflavin kinase activity
CO704_RS19900	COG0583	DNA-binding transcription factor activity
CO704_RS19915	COG0443	Heat shock 70 kDa protein
CO704_RS19920	COG1584	GPR1 FUN34 yaaH family protein
CO704_RS19925	COG0477	Major facilitator Superfamily
CO704_RS19930	COG0521	Mo-molybdopterin cofactor biosynthetic process
CO704_RS19935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CO704_RS19940	COG1115	amino acid carrier protein
CO704_RS19945	COG3022	response to hydroperoxide
CO704_RS19955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CO704_RS19965	COG0527	aspartate kinase activity
CO704_RS19965	COG0460	homoserine dehydrogenase
CO704_RS19975	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CO704_RS19985	COG0745	RESPONSE REGULATOR receiver
CO704_RS19990	COG2936	dipeptidyl-peptidase activity
CO704_RS20000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CO704_RS20010	COG0747	negative chemotaxis
CO704_RS20025	COG3045	CreA protein
CO704_RS20030	COG2207	Transcriptional regulator
CO704_RS20030	COG3708	Transcriptional regulator
CO704_RS20050	COG0741	lytic transglycosylase activity
CO704_RS20055	COG0488	(ABC) transporter
CO704_RS20065	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CO704_RS20070	COG0560	Phosphoserine phosphatase
CO704_RS20075	COG3726	membrane protein affecting hemolysin expression
CO704_RS20085	COG3550	peptidyl-serine autophosphorylation
CO704_RS20115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CO704_RS20120	COG0084	hydrolase, TatD family'
CO704_RS20125	COG4667	esterase of the alpha-beta hydrolase superfamily
CO704_RS20135	COG2823	Periplasmic or secreted lipoprotein
CO704_RS20145	COG1011	Hydrolase
CO704_RS20150	COG0456	acetyltransferase
CO704_RS20155	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CO704_RS20185	COG3706	GGDEF domain
CO704_RS20190	COG4114	ferric iron reductase
CO704_RS20195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CO704_RS20205	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CO704_RS20210	COG2207	Transcriptional regulator
CO704_RS20220	COG2966	Psort location CytoplasmicMembrane, score
CO704_RS20230	COG1846	Transcriptional regulator
CO704_RS20235	COG1764	response to oxidative stress
CO704_RS20245	COG2134	cdp-diacylglycerol pyrophosphatase
CO704_RS20255	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CO704_RS20260	COG2252	PERMEase
CO704_RS20275	COG3025	triphosphatase activity
CO704_RS20280	COG4991	sh3 domain protein
CO704_RS20295	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CO704_RS20310	COG0134	indole-3-glycerol-phosphate synthase activity
CO704_RS20320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CO704_RS20325	COG0358	DNA primase activity
CO704_RS20365	COG0840	transmembrane signaling receptor activity
CO704_RS20380	COG0583	DNA-binding transcription factor activity
CO704_RS20390	COG3845	ABC transporter
CO704_RS20395	COG4603	Belongs to the binding-protein-dependent transport system permease family
CO704_RS20400	COG1079	Belongs to the binding-protein-dependent transport system permease family
CO704_RS20415	COG2723	6-phospho-beta-galactosidase activity
CO704_RS20425	COG2188	Transcriptional regulator
CO704_RS20435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CO704_RS20450	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CO704_RS20455	COG3038	cytochrome b561
CO704_RS20475	COG2186	Transcriptional regulator
CO704_RS20485	COG1278	Cold shock
CO704_RS20490	COG2130	NADP-dependent
CO704_RS20495	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CO704_RS20515	COG3052	prosthetic group binding
CO704_RS20525	COG0179	Fumarylacetoacetate (FAA) hydrolase
CO704_RS20530	COG3493	citrate carrier protein
CO704_RS20545	COG0840	transmembrane signaling receptor activity
CO704_RS20550	COG0477	Major facilitator Superfamily
CO704_RS20555	COG0747	negative chemotaxis
CO704_RS20560	COG0601	transmembrane transport
CO704_RS20565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CO704_RS20570	COG0444	Belongs to the ABC transporter superfamily
CO704_RS20575	COG4608	Belongs to the ABC transporter superfamily
CO704_RS20580	COG3706	GGDEF domain
CO704_RS20595	COG1830	Aldolase
CO704_RS20605	COG0596	Alpha beta hydrolase
CO704_RS20615	COG2205	protein histidine kinase activity
CO704_RS20625	COG1902	pentaerythritol trinitrate reductase activity
CO704_RS20625	COG0446	pyridine nucleotide-disulphide oxidoreductase
CO704_RS20635	COG1451	nucleotide metabolic process
CO704_RS20640	COG0673	inositol 2-dehydrogenase activity
CO704_RS20655	COG2721	sulfolactate sulfo-lyase activity
CO704_RS20665	COG2271	Major facilitator Superfamily
CO704_RS20670	COG2186	Transcriptional regulator
CO704_RS20675	COG0586	Pfam SNARE associated Golgi protein
CO704_RS20685	COG1422	Protein of unknown function (DUF1090)
CO704_RS20690	COG4575	ribosome binding
CO704_RS20695	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CO704_RS20705	COG2259	Doxx family
CO704_RS20710	COG0435	Glutathione S-transferase
CO704_RS20715	COG3152	Membrane
CO704_RS20720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CO704_RS20745	COG2105	PFAM AIG2 family protein
CO704_RS20750	COG2911	Protein conserved in bacteria
CO704_RS20755	COG0729	surface antigen
CO704_RS20775	COG1253	flavin adenine dinucleotide binding
CO704_RS20785	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CO704_RS20790	COG1218	3'(2'),5'-bisphosphate nucleotidase
CO704_RS20800	COG1733	regulation of RNA biosynthetic process
CO704_RS20805	COG0702	epimerase
CO704_RS20815	COG0697	spore germination
CO704_RS20820	COG0840	transmembrane signaling receptor activity
CO704_RS20830	COG1113	amino acid transport
CO704_RS20835	COG0545	Peptidyl-prolyl cis-trans isomerase
CO704_RS20840	COG3061	Opacity-associated protein A
CO704_RS20850	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CO704_RS20885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS20890	COG3414	Phosphotransferase system galactitol-specific IIB component
CO704_RS20910	COG1073	alpha beta
CO704_RS20915	COG3650	response to hydrogen peroxide
CO704_RS20925	COG1960	acyl-CoA dehydrogenase activity
CO704_RS20935	COG0557	exoribonuclease II activity
CO704_RS20950	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CO704_RS20955	COG0330	HflC and HflK could
CO704_RS20960	COG0330	HflC and HflK could
CO704_RS20965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CO704_RS20970	COG1923	regulation of RNA biosynthetic process
CO704_RS20975	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CO704_RS20990	COG0802	atpase or kinase
CO704_RS20995	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CO704_RS20995	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CO704_RS21000	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CO704_RS21035	COG3264	Mechanosensitive ion channel
CO704_RS21035	COG1511	domain protein
CO704_RS21040	COG0583	DNA-binding transcription factor activity
CO704_RS21045	COG1741	Belongs to the pirin family
CO704_RS21050	COG0463	Glycosyl transferase, family 2
CO704_RS21055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CO704_RS21065	COG2223	nitrite transmembrane transporter activity
CO704_RS21075	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CO704_RS21080	COG0456	acetyltransferase
CO704_RS21090	COG1349	DNA-binding transcription factor activity
CO704_RS21105	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO704_RS21115	COG3716	PTS system mannose fructose sorbose family IID component
CO704_RS21120	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS21125	COG2222	sugar isomerase
CO704_RS21130	COG0191	fructose-bisphosphate aldolase activity
CO704_RS21145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CO704_RS21160	COG0792	nuclease activity
CO704_RS21170	COG2823	Periplasmic or secreted lipoprotein
CO704_RS21175	COG3711	transcriptional antiterminator
CO704_RS21175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO704_RS21195	COG3964	amidohydrolase
CO704_RS21240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CO704_RS21250	COG0679	Auxin Efflux Carrier
CO704_RS21295	COG0312	modulator of DNA gyrase
CO704_RS21300	COG3028	Belongs to the UPF0307 family
CO704_RS21305	COG1280	lysine exporter protein (LysE YggA)
CO704_RS21320	COG1053	succinate dehydrogenase
CO704_RS21325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CO704_RS21335	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CO704_RS21340	COG0583	DNA-binding transcription factor activity
CO704_RS21355	COG2076	Multidrug Resistance protein
CO704_RS21365	COG5510	response to toxic substance
CO704_RS21370	COG5510	response to toxic substance
CO704_RS21380	COG1509	lysine 2,3-aminomutase activity
CO704_RS21400	COG3030	protein affecting phage T7 exclusion by the F plasmid
CO704_RS21410	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CO704_RS21425	COG1309	transcriptional regulator
CO704_RS21435	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CO704_RS21465	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS21565	COG3436	PFAM IS66 Orf2 family protein
CO704_RS21570	COG4372	Transposase
CO704_RS21705	COG3436	PFAM IS66 Orf2 family protein
CO704_RS21710	COG4372	Transposase
CO704_RS21745	COG5455	response to cobalt ion
CO704_RS21750	COG2771	luxR family
CO704_RS21750	COG2200	EAL domain
CO704_RS21760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO704_RS21830	COG0464	growth
CO704_RS21940	COG0725	ABC transporter, periplasmic molybdate-binding protein
CO704_RS22100	COG3501	Rhs element vgr protein
CO704_RS22180	COG0305	Participates in initiation and elongation during chromosome replication
CO704_RS22205	COG4771	TonB-dependent receptor
CO704_RS22220	COG3721	Heme iron utilization protein
CO704_RS22235	COG0625	glutathione transferase activity
CO704_RS22245	COG1121	(ABC) transporter
CO704_RS22250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CO704_RS22255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CO704_RS22270	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CO704_RS22280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CO704_RS22285	COG2723	6-phospho-beta-galactosidase activity
CO704_RS22310	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CO704_RS22320	COG2824	Alkylphosphonate utilization operon protein PhnA
CO704_RS22325	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CO704_RS22330	COG2188	Transcriptional regulator
CO704_RS22335	COG3624	Phosphonate C-P lyase system protein PhnG
CO704_RS22340	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CO704_RS22345	COG3626	phosphonate metabolism
CO704_RS22350	COG3627	carbon phosphorus lyase activity
CO704_RS22355	COG4107	phosphonate C-P lyase system protein PhnK
CO704_RS22360	COG4778	phosphonate C-P lyase system protein PhnL
CO704_RS22365	COG3454	Phosphonate metabolism
CO704_RS22370	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CO704_RS22375	COG0456	acetyltransferase
CO704_RS22380	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CO704_RS22390	COG0698	ribose 5-phosphate isomerase
CO704_RS22395	COG1737	Transcriptional regulator
CO704_RS22400	COG1879	ABC-type sugar transport system periplasmic component
CO704_RS22405	COG1129	ABC transporter
CO704_RS22410	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO704_RS22415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CO704_RS22420	COG1940	carbohydrate kinase activity
CO704_RS22435	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO704_RS22460	COG1301	dicarboxylic acid transport
CO704_RS22470	COG3162	membrane
CO704_RS22475	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CO704_RS22480	COG1346	cytolysis
CO704_RS22485	COG1380	Effector of murein hydrolase LrgA
CO704_RS22490	COG0583	DNA-binding transcription factor activity
CO704_RS22495	COG0025	NhaP-type Na H and K H
CO704_RS22500	COG2252	PERMEase
CO704_RS22510	COG0789	Transcriptional regulator
CO704_RS22525	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CO704_RS22540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CO704_RS22555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CO704_RS22560	COG0076	glutamate decarboxylase activity
CO704_RS22595	COG2315	Protein conserved in bacteria
CO704_RS22600	COG3700	Belongs to the class B bacterial acid phosphatase family
CO704_RS22605	COG1448	Aminotransferase
CO704_RS22625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CO704_RS22640	COG0735	belongs to the Fur family
CO704_RS22645	COG3237	CsbD-like
CO704_RS22650	COG0534	Mate efflux family protein
CO704_RS22660	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CO704_RS22675	COG3161	chorismate lyase activity
CO704_RS22685	COG4580	involved in the transport of maltose and maltodextrins
CO704_RS22705	COG3833	ABC-type maltose transport systems, permease component
CO704_RS22715	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CO704_RS22750	COG0527	aspartate kinase activity
CO704_RS22780	COG1283	sodium-dependent phosphate transmembrane transporter activity
CO704_RS22785	COG0646	methionine synthase
CO704_RS22785	COG1410	methionine synthase
CO704_RS22805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CO704_RS22845	COG0151	Belongs to the GarS family
CO704_RS22880	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CO704_RS22895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CO704_RS22900	COG2104	thiamine diphosphate biosynthetic process
CO704_RS22920	COG1447	Phosphotransferase system cellobiose-specific component IIA
CO704_RS22925	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CO704_RS22935	COG0085	RNA polymerase activity
CO704_RS22945	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CO704_RS22965	COG0250	Participates in transcription elongation, termination and antitermination
CO704_RS22970	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CO704_RS23010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CO704_RS23040	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CO704_RS23050	COG1739	Uncharacterized protein family UPF0029
CO704_RS23095	COG0084	hydrolase, TatD family'
CO704_RS23100	COG0805	protein transport
CO704_RS23105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CO704_RS23115	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CO704_RS23130	COG1322	Protein conserved in bacteria
CO704_RS23140	COG0412	Dienelactone hydrolase
CO704_RS23150	COG0583	DNA-binding transcription factor activity
CO704_RS23160	COG0561	phosphatase activity
CO704_RS23165	COG2267	carboxylic ester hydrolase activity
CO704_RS23170	COG1280	lysine exporter protein (LysE YggA)
CO704_RS23175	COG1280	lysine exporter protein (LysE YggA)
CO704_RS23180	COG0514	ATP-dependent DNA helicase (RecQ)
CO704_RS23185	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CO704_RS23195	COG2962	Rard protein
CO704_RS23200	COG0598	Magnesium transport protein CorA
CO704_RS23205	COG0210	DNA helicase
CO704_RS23210	COG1011	Hydrolase
CO704_RS23260	COG2959	enzyme of heme biosynthesis
CO704_RS23265	COG3071	HemY protein
CO704_RS23320	COG2244	polysaccharide biosynthetic process
CO704_RS23325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CO704_RS23330	COG0456	acetyltransferase
CO704_RS23335	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CO704_RS23345	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CO704_RS23350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CO704_RS23355	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CO704_RS23360	COG3118	belongs to the thioredoxin family
CO704_RS23370	COG0248	Ppx GppA phosphatase
CO704_RS23400	COG0583	DNA-binding transcription factor activity
CO704_RS23420	COG3978	acetolactate synthase activity
CO704_RS23440	COG3085	chromosome segregation
CO704_RS23510	COG0583	DNA-binding transcription factor activity
CO704_RS23515	COG0165	Argininosuccinate lyase
CO704_RS23530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CO704_RS23545	COG2194	sulfuric ester hydrolase activity
CO704_RS23555	COG0460	homoserine dehydrogenase
CO704_RS23555	COG0527	aspartate kinase activity
CO704_RS23560	COG0626	cystathionine gamma-synthase activity
CO704_RS23570	COG0254	rRNA binding
CO704_RS23575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CO704_RS23580	COG1609	Transcriptional regulator
CO704_RS23590	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CO704_RS23605	COG1575	Belongs to the MenA family. Type 1 subfamily
CO704_RS23615	COG3074	FtsZ-dependent cytokinesis
CO704_RS23625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CO704_RS23630	COG1494	fructose-1,6-bisphosphatase
CO704_RS23640	COG3152	Membrane
CO704_RS23650	COG0149	triose-phosphate isomerase activity
CO704_RS23660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CO704_RS23675	COG3678	ATP-independent chaperone mediated protein folding
CO704_RS23680	COG0745	RESPONSE REGULATOR receiver
CO704_RS23685	COG2205	protein histidine kinase activity
CO704_RS23690	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CO704_RS23710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CO704_RS23715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CO704_RS23725	COG4942	peptidase
CO704_RS23730	COG2861	carbohydrate metabolic process
CO704_RS23755	COG0859	PFAM glycosyl transferase family 9
CO704_RS23760	COG0859	PFAM glycosyl transferase family 9
CO704_RS23775	COG0515	serine threonine protein kinase
CO704_RS23780	COG0438	transferase activity, transferring glycosyl groups
CO704_RS23785	COG0859	PFAM glycosyl transferase family 9
CO704_RS23790	COG1519	Transferase
CO704_RS23810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CO704_RS23820	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CO704_RS23835	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CO704_RS23845	COG1561	YicC-like family, N-terminal region
CO704_RS23855	COG2860	membrane
CO704_RS23865	COG0194	GDP metabolic process
CO704_RS23875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CO704_RS23880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CO704_RS23885	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CO704_RS23890	COG0786	glutamate:sodium symporter activity
CO704_RS23895	COG2233	PERMEase
CO704_RS23900	COG2982	Protein involved in outer membrane biogenesis
CO704_RS23905	COG0456	acetyltransferase
CO704_RS23920	COG1011	Hydrolase
CO704_RS23935	COG0174	glutamine synthetase
CO704_RS23940	COG3852	Histidine kinase
CO704_RS23945	COG2204	response regulator
CO704_RS23950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CO704_RS23955	COG3078	GTPase activator activity
CO704_RS23965	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CO704_RS23965	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CO704_RS23970	COG0204	Acyl-transferase
CO704_RS23980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CO704_RS23985	COG3084	Protein conserved in bacteria
CO704_RS23990	COG0746	molybdenum cofactor guanylyltransferase activity
CO704_RS23995	COG1763	Mo-molybdopterin cofactor biosynthetic process
CO704_RS24020	COG2186	Transcriptional regulator
CO704_RS24025	COG0477	Major facilitator Superfamily
CO704_RS24030	COG1609	Transcriptional regulator
CO704_RS24035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO704_RS24045	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO704_RS24050	COG1129	ABC transporter
CO704_RS24080	COG1522	sequence-specific DNA binding
CO704_RS24085	COG0716	FMN binding
CO704_RS24100	COG3312	ion transport
CO704_RS24120	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CO704_RS24125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CO704_RS24135	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CO704_RS24150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CO704_RS24155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CO704_RS24160	COG0573	inorganic phosphate transmembrane transporter activity
CO704_RS24165	COG0581	inorganic phosphate transmembrane transporter activity
CO704_RS24170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CO704_RS24175	COG0704	Plays a role in the regulation of phosphate uptake
CO704_RS24180	COG2258	MOSC domain
CO704_RS24200	COG0835	chemotaxis
CO704_RS24200	COG0784	Response regulator, receiver
CO704_RS24215	COG0309	Hydrogenase expression formation protein (HypE)
CO704_RS24220	COG0409	Hydrogenase expression formation protein
CO704_RS24225	COG0298	carbon dioxide binding
CO704_RS24230	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CO704_RS24235	COG0375	protein maturation
CO704_RS24245	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO704_RS24250	COG0651	ATP synthesis coupled electron transport
CO704_RS24255	COG0650	Formate hydrogenlyase subunit 4
CO704_RS24260	COG3261	NADH dehydrogenase
CO704_RS24260	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CO704_RS24265	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CO704_RS24270	COG3260	NADH ubiquinone oxidoreductase 20
CO704_RS24280	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CO704_RS24285	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO704_RS24290	COG3383	formate dehydrogenase (NAD+) activity
CO704_RS24295	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CO704_RS24300	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CO704_RS24305	COG3977	Valine--pyruvate aminotransferase
CO704_RS24310	COG0366	Alpha amylase catalytic
CO704_RS24320	COG2992	FlgJ-related protein
CO704_RS24325	COG2207	Transcriptional regulator
CO704_RS24325	COG1609	Transcriptional regulator
CO704_RS24330	COG4214	carbohydrate transport
CO704_RS24340	COG4213	ABC transporter substrate-binding protein
CO704_RS24345	COG2115	Belongs to the xylose isomerase family
CO704_RS24350	COG1070	Carbohydrate kinase
CO704_RS24365	COG3274	enterobacterial common antigen metabolic process
CO704_RS24375	COG0752	glycyl-tRNA synthetase alpha subunit
CO704_RS24390	COG2944	sequence-specific DNA binding
CO704_RS24420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO704_RS24430	COG1609	Transcriptional regulator
CO704_RS24435	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CO704_RS24445	COG0457	Tetratricopeptide repeat
CO704_RS24450	COG1215	transferase activity, transferring glycosyl groups
CO704_RS24490	COG4608	Belongs to the ABC transporter superfamily
CO704_RS24495	COG0444	Belongs to the ABC transporter superfamily
CO704_RS24500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CO704_RS24505	COG0601	transmembrane transport
CO704_RS24510	COG0747	negative chemotaxis
CO704_RS24515	COG2194	sulfuric ester hydrolase activity
CO704_RS24520	COG1368	sulfuric ester hydrolase activity
CO704_RS24525	COG2223	nitrite transmembrane transporter activity
CO704_RS24530	COG2818	Glycosylase
CO704_RS24540	COG0243	molybdopterin cofactor binding
CO704_RS24550	COG2194	sulfuric ester hydrolase activity
CO704_RS24575	COG1215	transferase activity, transferring glycosyl groups
CO704_RS24580	COG1215	transferase activity, transferring glycosyl groups
CO704_RS24585	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CO704_RS24590	COG3118	belongs to the thioredoxin family
CO704_RS24590	COG0457	Tetratricopeptide repeat
CO704_RS24595	COG2200	EAL domain
CO704_RS24595	COG2199	diguanylate cyclase activity
CO704_RS24605	COG0612	Peptidase, M16
CO704_RS24615	COG2200	EAL domain
CO704_RS24620	COG2982	Protein involved in outer membrane biogenesis
CO704_RS24625	COG0477	Major facilitator Superfamily
CO704_RS24635	COG1295	ribonuclease BN
CO704_RS24640	COG0583	DNA-binding transcription factor activity
CO704_RS24645	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS24650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CO704_RS24655	COG2252	PERMEase
CO704_RS24660	COG0431	NADPH-dependent FMN reductase
CO704_RS24665	COG2091	lysine biosynthetic process via aminoadipic acid
CO704_RS24675	COG0706	membrane insertase activity
CO704_RS24690	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CO704_RS24700	COG0592	DNA-directed DNA polymerase activity
CO704_RS24715	COG3753	Protein conserved in bacteria
CO704_RS24720	COG0561	phosphatase activity
CO704_RS24725	COG2186	Transcriptional regulator
CO704_RS24730	COG3734	2-keto-3-deoxy-galactonokinase
CO704_RS24735	COG0800	Aldolase
CO704_RS24745	COG2271	Major facilitator Superfamily
CO704_RS24750	COG2957	Belongs to the agmatine deiminase family
CO704_RS24760	COG0823	Involved in the tonB-independent uptake of proteins
CO704_RS24765	COG5645	(Lipo)protein
CO704_RS24785	COG2188	Transcriptional regulator
CO704_RS24810	COG0765	amino acid transport
CO704_RS24815	COG1126	abc transporter atp-binding protein
CO704_RS24825	COG1609	Transcriptional regulator
CO704_RS24830	COG0477	Major facilitator Superfamily
CO704_RS24840	COG2610	gluconate transmembrane transporter activity
CO704_RS24845	COG0583	DNA-binding transcription factor activity
CO704_RS24850	COG2814	Major facilitator Superfamily
CO704_RS24955	COG2197	response regulator
CO704_RS25005	COG3158	transport of potassium into the cell
CO704_RS25015	COG3093	addiction module antidote protein HigA
CO704_RS25030	COG0402	S-adenosylhomocysteine deaminase activity
CO704_RS25035	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CO704_RS25035	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CO704_RS25090	COG0778	Nitroreductase
CO704_RS25130	COG3177	Filamentation induced by cAMP protein fic
CO704_RS25175	COG2801	Transposase and inactivated derivatives
CO704_RS25245	COG3713	MltA-interacting MipA family protein
CO704_RS25270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO704_RS25290	COG3655	Transcriptional regulator
CO704_RS25310	COG3397	chitin binding
CO704_RS25365	COG3547	Transposase (IS116 IS110 IS902 family)
CO704_RS25440	COG2990	Protein conserved in bacteria
CO704_RS25450	COG4372	Transposase
CO704_RS25545	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CO704_RS25605	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CO704_RS25630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CO704_RS25650	COG1216	Glycosyl transferase, family 2
CO704_RS25685	COG1028	Short-chain dehydrogenase reductase Sdr
CO704_RS25695	COG2091	lysine biosynthetic process via aminoadipic acid
CO704_RS25705	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CO704_RS25980	COG1802	Transcriptional regulator
CO704_RS26010	COG0183	Belongs to the thiolase family
CO704_RS26020	COG3243	poly(R)-hydroxyalkanoic acid synthase