locus-tag	class	description
LH23_RS00030	COG2204	response regulator
LH23_RS00035	COG3170	Tfp pilus assembly protein FimV
LH23_RS00040	COG2205	protein histidine kinase activity
LH23_RS00060	COG0560	Phosphoserine phosphatase
LH23_RS00065	COG1737	Transcriptional regulator
LH23_RS00070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LH23_RS00155	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LH23_RS00165	COG3772	lysozyme
LH23_RS00185	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LH23_RS00195	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LH23_RS00200	COG1381	Involved in DNA repair and RecF pathway recombination
LH23_RS00205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LH23_RS00215	COG0681	Belongs to the peptidase S26 family
LH23_RS00225	COG3086	response to oxidative stress
LH23_RS00230	COG3026	antisigma factor binding
LH23_RS00250	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LH23_RS00255	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LH23_RS00260	COG0513	Belongs to the DEAD box helicase family
LH23_RS00265	COG0583	DNA-binding transcription factor activity
LH23_RS00285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LH23_RS00290	COG3118	belongs to the thioredoxin family
LH23_RS00295	COG3148	PFAM DTW domain containing protein
LH23_RS00305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LH23_RS00310	COG0477	Major facilitator Superfamily
LH23_RS00340	COG0542	response to heat
LH23_RS00355	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LH23_RS00360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LH23_RS00365	COG1605	Chorismate mutase
LH23_RS00365	COG0077	Prephenate dehydratase
LH23_RS00375	COG1605	Chorismate mutase
LH23_RS00375	COG0287	Prephenate dehydrogenase
LH23_RS00390	COG2199	diguanylate cyclase activity
LH23_RS00395	COG2885	chlorophyll binding
LH23_RS00400	COG0335	large ribosomal subunit rRNA binding
LH23_RS00420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LH23_RS00425	COG4137	Cytochrome C assembly protein
LH23_RS00430	COG4536	flavin adenine dinucleotide binding
LH23_RS00440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LH23_RS00445	COG0497	DNA recombination
LH23_RS00460	COG2867	negative regulation of translational initiation
LH23_RS00485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LH23_RS00535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LH23_RS00575	COG2207	Transcriptional regulator
LH23_RS00595	COG2944	sequence-specific DNA binding
LH23_RS00605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LH23_RS00615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LH23_RS00635	COG2207	Transcriptional regulator
LH23_RS00640	COG0667	Aldo Keto reductase
LH23_RS00645	COG0583	DNA-binding transcription factor activity
LH23_RS00650	COG0667	Aldo Keto reductase
LH23_RS00670	COG0406	alpha-ribazole phosphatase activity
LH23_RS00675	COG0640	Transcriptional regulator
LH23_RS00680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LH23_RS00705	COG4575	ribosome binding
LH23_RS00715	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LH23_RS00720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LH23_RS00725	COG1780	Probably involved in ribonucleotide reductase function
LH23_RS00750	COG4176	ABC-type proline glycine betaine transport system permease component
LH23_RS00760	COG2814	Major facilitator Superfamily
LH23_RS00765	COG1846	Transcriptional regulator
LH23_RS00770	COG1566	PFAM secretion protein HlyD family protein
LH23_RS00775	COG2814	Major facilitator Superfamily
LH23_RS00780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LH23_RS00785	COG1917	Cupin 2, conserved barrel domain protein
LH23_RS00785	COG4977	sequence-specific DNA binding
LH23_RS00800	COG1238	metal cluster binding
LH23_RS00805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LH23_RS00835	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LH23_RS00845	COG2137	regulation of response to DNA damage stimulus
LH23_RS00855	COG1546	Belongs to the CinA family
LH23_RS00860	COG0803	Belongs to the bacterial solute-binding protein 9 family
LH23_RS00865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LH23_RS00875	COG3730	PTS system glucitol sorbitol-specific
LH23_RS00880	COG3732	PTS system glucitol sorbitol-specific
LH23_RS00890	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS00895	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS00900	COG1349	DNA-binding transcription factor activity
LH23_RS00905	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LH23_RS00905	COG0517	IMP dehydrogenase activity
LH23_RS00910	COG2951	lytic endotransglycosylase activity
LH23_RS00935	COG1595	DNA-templated transcription, initiation
LH23_RS00940	COG3038	cytochrome b561
LH23_RS00945	COG0753	catalase activity
LH23_RS00950	COG0840	transmembrane signaling receptor activity
LH23_RS00975	COG4942	peptidase
LH23_RS00975	COG1388	LysM domain
LH23_RS01030	COG2234	aminopeptidase activity
LH23_RS01060	COG0720	synthase
LH23_RS01065	COG0644	oxidoreductase
LH23_RS01070	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LH23_RS01075	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LH23_RS01085	COG2086	electron transfer activity
LH23_RS01090	COG0477	Major facilitator Superfamily
LH23_RS01095	COG0277	FAD linked oxidase domain protein
LH23_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS01105	COG2223	nitrite transmembrane transporter activity
LH23_RS01110	COG1070	Carbohydrate kinase
LH23_RS01115	COG0602	queuosine metabolic process
LH23_RS01120	COG3366	ferrous iron transmembrane transporter activity
LH23_RS01125	COG0700	Nucleoside recognition
LH23_RS01140	COG0148	phosphopyruvate hydratase activity
LH23_RS01150	COG3956	TIGRFAM MazG family protein
LH23_RS01155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LH23_RS01160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LH23_RS01165	COG4999	Histidine kinase
LH23_RS01165	COG3850	Histidine kinase
LH23_RS01165	COG3437	response regulator, receiver
LH23_RS01165	COG2205	protein histidine kinase activity
LH23_RS01170	COG1309	transcriptional regulator
LH23_RS01185	COG0716	FMN binding
LH23_RS01190	COG0564	pseudouridine synthase activity
LH23_RS01195	COG3098	single-species biofilm formation
LH23_RS01210	COG1611	Belongs to the LOG family
LH23_RS01215	COG0814	amino acid
LH23_RS01220	COG1760	l-serine dehydratase
LH23_RS01225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LH23_RS01240	COG2363	Small membrane protein
LH23_RS01245	COG0583	DNA-binding transcription factor activity
LH23_RS01255	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LH23_RS01260	COG2166	iron-sulfur cluster assembly
LH23_RS01265	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LH23_RS01270	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LH23_RS01290	COG0860	N-Acetylmuramoyl-L-alanine amidase
LH23_RS01295	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LH23_RS01295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LH23_RS01300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LH23_RS01305	COG1074	ATP-dependent DNA helicase activity
LH23_RS01315	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LH23_RS01325	COG4795	General secretion pathway protein
LH23_RS01335	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LH23_RS01365	COG0667	Aldo Keto reductase
LH23_RS01370	COG0477	Major facilitator Superfamily
LH23_RS01380	COG1609	Transcriptional regulator
LH23_RS01390	COG1609	Transcriptional regulator
LH23_RS01400	COG0583	DNA-binding transcription factor activity
LH23_RS01405	COG2814	Major facilitator Superfamily
LH23_RS01410	COG1794	racemase activity, acting on amino acids and derivatives
LH23_RS01415	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LH23_RS01420	COG0583	DNA-binding transcription factor activity
LH23_RS01425	COG0477	Major facilitator Superfamily
LH23_RS01435	COG0667	Aldo Keto reductase
LH23_RS01445	COG2814	Major facilitator Superfamily
LH23_RS01480	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS01485	COG0840	transmembrane signaling receptor activity
LH23_RS01490	COG0840	transmembrane signaling receptor activity
LH23_RS01510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LH23_RS01515	COG0583	DNA-binding transcription factor activity
LH23_RS01530	COG2207	Transcriptional regulator
LH23_RS01535	COG0300	oxidoreductase activity
LH23_RS01550	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LH23_RS01575	COG4942	peptidase
LH23_RS01580	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LH23_RS01590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LH23_RS01600	COG4974	Belongs to the 'phage' integrase family
LH23_RS01615	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LH23_RS01625	COG1272	protein, Hemolysin III
LH23_RS01635	COG1737	Transcriptional regulator
LH23_RS01640	COG2723	6-phospho-beta-galactosidase activity
LH23_RS01645	COG5002	protein histidine kinase activity
LH23_RS01650	COG0745	RESPONSE REGULATOR receiver
LH23_RS01655	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
LH23_RS01660	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LH23_RS01685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LH23_RS01690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LH23_RS01695	COG0006	proline dipeptidase activity
LH23_RS01700	COG3079	Belongs to the UPF0149 family
LH23_RS01710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LH23_RS01715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LH23_RS01730	COG2968	Membrane
LH23_RS01740	COG0668	transmembrane transport
LH23_RS01745	COG1882	Formate acetyltransferase
LH23_RS01750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LH23_RS01755	COG0814	amino acid
LH23_RS01765	COG0583	DNA-binding transcription factor activity
LH23_RS01770	COG0191	fructose-bisphosphate aldolase activity
LH23_RS01775	COG0126	phosphoglycerate kinase activity
LH23_RS01785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LH23_RS01790	COG0501	Belongs to the peptidase M48B family
LH23_RS01805	COG3716	PTS system mannose fructose sorbose family IID component
LH23_RS01810	COG3715	PTS system
LH23_RS01815	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LH23_RS01815	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS01840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LH23_RS01845	COG2814	Major facilitator Superfamily
LH23_RS01850	COG3091	SprT-like family
LH23_RS01855	COG2356	endonuclease I
LH23_RS01860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LH23_RS01875	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LH23_RS01890	COG2805	Type II/IV secretion system protein
LH23_RS01895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LH23_RS01900	COG0762	integral membrane protein
LH23_RS01915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LH23_RS01925	COG3171	Protein conserved in bacteria
LH23_RS01935	COG1194	a g-specific adenine glycosylase
LH23_RS01945	COG0741	lytic transglycosylase activity
LH23_RS01950	COG1982	Orn Lys Arg decarboxylase major
LH23_RS01965	COG1475	DNA binding
LH23_RS01970	COG3969	phosphoadenosine phosphosulfate
LH23_RS01975	COG0754	glutathionylspermidine amidase activity
LH23_RS01980	COG3718	enzyme involved in inositol metabolism
LH23_RS01990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LH23_RS01995	COG0673	inositol 2-dehydrogenase activity
LH23_RS02000	COG1172	Belongs to the binding-protein-dependent transport system permease family
LH23_RS02005	COG1129	ABC transporter
LH23_RS02015	COG0673	inositol 2-dehydrogenase activity
LH23_RS02020	COG3962	Belongs to the TPP enzyme family
LH23_RS02035	COG0667	Aldo Keto reductase
LH23_RS02060	COG0848	biopolymer transport protein
LH23_RS02070	COG0626	cystathionine gamma-synthase activity
LH23_RS02075	COG0586	Pfam SNARE associated Golgi protein
LH23_RS02080	COG2207	Transcriptional regulator
LH23_RS02085	COG1979	alcohol dehydrogenase
LH23_RS02090	COG0656	L-ascorbic acid biosynthetic process
LH23_RS02100	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LH23_RS02110	COG3639	organic phosphonate transmembrane transporter activity
LH23_RS02120	COG1032	radical SAM domain protein
LH23_RS02135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LH23_RS02140	COG3111	PFAM Bacterial OB fold (BOF) protein
LH23_RS02150	COG0642	Histidine kinase
LH23_RS02155	COG2249	NAD(P)H dehydrogenase (quinone) activity
LH23_RS02160	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LH23_RS02170	COG3150	esterase
LH23_RS02175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LH23_RS02180	COG3151	Protein conserved in bacteria
LH23_RS02185	COG0494	nUDIX hydrolase
LH23_RS02190	COG1538	Outer membrane efflux protein
LH23_RS02200	COG0754	glutathionylspermidine amidase activity
LH23_RS02205	COG3384	dioxygenase
LH23_RS02225	COG1473	amidohydrolase
LH23_RS02240	COG0840	transmembrane signaling receptor activity
LH23_RS02300	COG2175	clavaminate synthase activity
LH23_RS02305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LH23_RS02310	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LH23_RS02315	COG4521	taurine ABC transporter
LH23_RS02320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LH23_RS02320	COG1263	PTS System
LH23_RS02325	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LH23_RS02330	COG0626	cystathionine gamma-synthase activity
LH23_RS02335	COG1301	dicarboxylic acid transport
LH23_RS02340	COG0583	DNA-binding transcription factor activity
LH23_RS02355	COG2814	Major facilitator Superfamily
LH23_RS02360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LH23_RS02375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LH23_RS02430	COG3423	Transcriptional regulator
LH23_RS02455	COG0582	viral genome integration into host DNA
LH23_RS02475	COG0673	inositol 2-dehydrogenase activity
LH23_RS02480	COG1064	alcohol dehydrogenase
LH23_RS02490	COG0433	COG0433 Predicted ATPase
LH23_RS02495	COG0814	amino acid
LH23_RS02500	COG0795	lipopolysaccharide-transporting ATPase activity
LH23_RS02505	COG0795	lipopolysaccharide-transporting ATPase activity
LH23_RS02515	COG2927	DNA polymerase III (CHI subunit)
LH23_RS02550	COG2197	response regulator
LH23_RS02570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LH23_RS02575	COG2235	arginine
LH23_RS02580	COG0549	Belongs to the carbamate kinase family
LH23_RS02610	COG0251	oxidation-reduction process
LH23_RS02615	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LH23_RS02630	COG1263	PTS System
LH23_RS02630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LH23_RS02635	COG0366	Alpha amylase catalytic
LH23_RS02640	COG2249	NAD(P)H dehydrogenase (quinone) activity
LH23_RS02655	COG0602	queuosine metabolic process
LH23_RS02660	COG1733	regulation of RNA biosynthetic process
LH23_RS02665	COG2249	NAD(P)H dehydrogenase (quinone) activity
LH23_RS02670	COG0701	Predicted permease
LH23_RS02675	COG0702	epimerase
LH23_RS02690	COG3153	acetyltransferase
LH23_RS02695	COG3154	lipid carrier protein
LH23_RS02700	COG0826	peptidase U32
LH23_RS02705	COG0826	peptidase U32
LH23_RS02710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LH23_RS02715	COG0814	amino acid
LH23_RS02720	COG0513	Belongs to the DEAD box helicase family
LH23_RS02735	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LH23_RS02755	COG0195	Participates in both transcription termination and antitermination
LH23_RS02775	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LH23_RS02785	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LH23_RS02800	COG1534	Rna-binding protein
LH23_RS02810	COG2027	D-alanyl-D-alanine carboxypeptidase
LH23_RS02815	COG0745	RESPONSE REGULATOR receiver
LH23_RS02820	COG0642	Histidine kinase
LH23_RS02830	COG0697	spore germination
LH23_RS02835	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LH23_RS02845	COG0142	geranyltranstransferase activity
LH23_RS02850	COG3423	Transcriptional regulator
LH23_RS02860	COG5007	Belongs to the BolA IbaG family
LH23_RS02865	COG3113	response to antibiotic
LH23_RS02870	COG2854	intermembrane phospholipid transfer
LH23_RS02875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LH23_RS02880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LH23_RS02885	COG1127	ABC transporter
LH23_RS02890	COG0530	calcium, potassium:sodium antiporter activity
LH23_RS02895	COG0517	IMP dehydrogenase activity
LH23_RS02895	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LH23_RS02900	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LH23_RS02905	COG3117	lipopolysaccharide transmembrane transporter activity
LH23_RS02910	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LH23_RS02915	COG1137	ATPase activity
LH23_RS02920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LH23_RS02925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LH23_RS02940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS02945	COG1929	Belongs to the glycerate kinase type-1 family
LH23_RS02950	COG2610	gluconate transmembrane transporter activity
LH23_RS02955	COG3835	regulator
LH23_RS02965	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LH23_RS02970	COG5002	protein histidine kinase activity
LH23_RS02970	COG0784	Response regulator, receiver
LH23_RS02970	COG2198	Histidine kinase
LH23_RS02975	COG1242	4 iron, 4 sulfur cluster binding
LH23_RS02980	COG0070	glutamate synthase
LH23_RS02980	COG0069	glutamate synthase activity
LH23_RS02980	COG0067	glutamate synthase
LH23_RS02985	COG0493	'glutamate synthase
LH23_RS02990	COG2969	positive regulation of protein catabolic process
LH23_RS02995	COG0625	glutathione transferase activity
LH23_RS03005	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LH23_RS03010	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LH23_RS03015	COG3105	Protein conserved in bacteria
LH23_RS03020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LH23_RS03025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LH23_RS03050	COG2732	(Barnase) inhibitor
LH23_RS03060	COG1289	transmembrane transporter activity
LH23_RS03065	COG1566	PFAM secretion protein HlyD family protein
LH23_RS03075	COG0583	DNA-binding transcription factor activity
LH23_RS03080	COG0312	modulator of DNA gyrase
LH23_RS03085	COG3164	Protein of unknown function
LH23_RS03100	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LH23_RS03105	COG1792	Involved in formation and maintenance of cell shape
LH23_RS03110	COG1077	Cell shape determining protein MreB Mrl
LH23_RS03115	COG2199	diguanylate cyclase activity
LH23_RS03115	COG2200	EAL domain
LH23_RS03120	COG0604	alcohol dehydrogenase
LH23_RS03135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LH23_RS03140	COG0511	ligase activity, forming carbon-carbon bonds
LH23_RS03145	COG0439	Biotin carboxylase
LH23_RS03150	COG3924	membrane
LH23_RS03155	COG4145	pantothenate transmembrane transporter activity
LH23_RS03180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LH23_RS03185	COG4597	amino acid ABC transporter
LH23_RS03190	COG0765	amino acid transport
LH23_RS03195	COG1126	abc transporter atp-binding protein
LH23_RS03235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LH23_RS03250	COG0009	L-threonylcarbamoyladenylate synthase
LH23_RS03255	COG0551	DNA topoisomerase type I activity
LH23_RS03265	COG0758	DNA mediated transformation
LH23_RS03295	COG0789	Transcriptional regulator
LH23_RS03335	COG0201	protein transport
LH23_RS03340	COG0200	Binds to the 23S rRNA
LH23_RS03345	COG1841	ribosomal large subunit assembly
LH23_RS03355	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LH23_RS03365	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LH23_RS03385	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LH23_RS03400	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LH23_RS03415	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LH23_RS03440	COG0051	transcription antitermination factor activity, RNA binding
LH23_RS03465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LH23_RS03470	COG0049	tRNA binding
LH23_RS03475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LH23_RS03480	COG2168	tRNA wobble position uridine thiolation
LH23_RS03485	COG2923	Belongs to the DsrF TusC family
LH23_RS03495	COG2964	Protein conserved in bacteria
LH23_RS03500	COG0545	Peptidyl-prolyl cis-trans isomerase
LH23_RS03510	COG1047	Peptidyl-prolyl cis-trans
LH23_RS03515	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LH23_RS03520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LH23_RS03520	COG0475	glutathione-regulated potassium exporter activity
LH23_RS03530	COG0488	(ABC) transporter
LH23_RS03540	COG0429	hydrolase of the alpha beta-hydrolase fold
LH23_RS03550	COG3954	Phosphoribulokinase
LH23_RS03555	COG1765	OsmC-like protein
LH23_RS03565	COG1289	transmembrane transporter activity
LH23_RS03585	COG0738	Major facilitator superfamily
LH23_RS03590	COG0625	glutathione transferase activity
LH23_RS03595	COG1017	nitric oxide dioxygenase activity
LH23_RS03595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LH23_RS03600	COG0583	DNA-binding transcription factor activity
LH23_RS03605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LH23_RS03610	COG2146	nitrite reductase [NAD(P)H] activity
LH23_RS03625	COG0626	cystathionine gamma-synthase activity
LH23_RS03640	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LH23_RS03645	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LH23_RS03650	COG3457	Alanine racemase
LH23_RS03660	COG2188	Transcriptional regulator
LH23_RS03675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LH23_RS03680	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LH23_RS03685	COG3266	domain, Protein
LH23_RS03695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LH23_RS03700	COG4796	Type ii and iii secretion system protein
LH23_RS03725	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LH23_RS03730	COG0494	nUDIX hydrolase
LH23_RS03740	COG1011	Hydrolase
LH23_RS03745	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LH23_RS03755	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LH23_RS03775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LH23_RS03780	COG2183	response to ionizing radiation
LH23_RS03785	COG1918	ferrous iron import across plasma membrane
LH23_RS03790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LH23_RS03825	COG1640	4-alpha-glucanotransferase
LH23_RS03830	COG0058	SHG alpha-glucan phosphorylase activity
LH23_RS03840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LH23_RS03855	COG1349	DNA-binding transcription factor activity
LH23_RS03860	COG0058	SHG alpha-glucan phosphorylase activity
LH23_RS03865	COG0297	glycogen (starch) synthase activity
LH23_RS03885	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LH23_RS03890	COG2095	MarC family integral membrane protein
LH23_RS03900	COG2610	gluconate transmembrane transporter activity
LH23_RS03905	COG3265	gluconokinase activity
LH23_RS03910	COG1609	Transcriptional regulator
LH23_RS03915	COG1741	Belongs to the pirin family
LH23_RS03920	COG0673	inositol 2-dehydrogenase activity
LH23_RS03925	COG1247	-acetyltransferase
LH23_RS03935	COG0405	Gamma-glutamyltransferase
LH23_RS03945	COG0584	glycerophosphoryl diester phosphodiesterase
LH23_RS03980	COG0411	ABC transporter
LH23_RS03985	COG4177	L-phenylalanine transmembrane transporter activity
LH23_RS03995	COG0683	leucine binding
LH23_RS04015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LH23_RS04025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LH23_RS04030	COG2177	Part of the ABC transporter FtsEX involved in
LH23_RS04035	COG2884	Cell division ATP-binding protein ftsE
LH23_RS04040	COG0552	protein localization to endoplasmic reticulum
LH23_RS04045	COG0742	ribosomal rna small subunit methyltransferase
LH23_RS04050	COG3776	membrane
LH23_RS04060	COG3714	YhhN family
LH23_RS04065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LH23_RS04065	COG1263	PTS System
LH23_RS04065	COG2190	(PTS) system
LH23_RS04070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LH23_RS04075	COG1609	Transcriptional regulator
LH23_RS04090	COG5499	transcription regulator containing HTH domain
LH23_RS04100	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LH23_RS04110	COG0628	permease
LH23_RS04125	COG0740	serine-type endopeptidase activity
LH23_RS04130	COG0697	spore germination
LH23_RS04140	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LH23_RS04150	COG1629	transport
LH23_RS04155	COG1595	DNA-templated transcription, initiation
LH23_RS04160	COG3712	iron ion homeostasis
LH23_RS04175	COG0561	phosphatase activity
LH23_RS04180	COG1349	DNA-binding transcription factor activity
LH23_RS04185	COG2081	HI0933 family
LH23_RS04190	COG0306	phosphate transporter
LH23_RS04200	COG0589	response to stress
LH23_RS04205	COG2852	Protein conserved in bacteria
LH23_RS04220	COG0671	phosphoesterase, PA-phosphatase related
LH23_RS04225	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LH23_RS04230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LH23_RS04285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LH23_RS04295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LH23_RS04315	COG3722	fumarate hydratase activity
LH23_RS04325	COG2213	PTS system mannitol-specific
LH23_RS04325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS04330	COG2249	NAD(P)H dehydrogenase (quinone) activity
LH23_RS04335	COG0583	DNA-binding transcription factor activity
LH23_RS04340	COG0625	glutathione transferase activity
LH23_RS04350	COG3276	selenocysteine insertion sequence binding
LH23_RS04355	COG1012	belongs to the aldehyde dehydrogenase family
LH23_RS04365	COG0243	molybdopterin cofactor binding
LH23_RS04365	COG3383	formate dehydrogenase (NAD+) activity
LH23_RS04370	COG3383	formate dehydrogenase (NAD+) activity
LH23_RS04370	COG0243	molybdopterin cofactor binding
LH23_RS04375	COG0437	4 iron, 4 sulfur cluster binding
LH23_RS04380	COG2864	formate dehydrogenase
LH23_RS04430	COG0583	DNA-binding transcription factor activity
LH23_RS04450	COG0300	oxidoreductase activity
LH23_RS04455	COG0583	DNA-binding transcription factor activity
LH23_RS04460	COG4773	Receptor
LH23_RS04465	COG2814	Major facilitator Superfamily
LH23_RS04470	COG0477	Major facilitator Superfamily
LH23_RS04475	COG1609	Transcriptional regulator
LH23_RS04485	COG1126	abc transporter atp-binding protein
LH23_RS04490	COG0765	amino acid transport
LH23_RS04525	COG2188	Transcriptional regulator
LH23_RS04545	COG5645	(Lipo)protein
LH23_RS04550	COG0823	Involved in the tonB-independent uptake of proteins
LH23_RS04560	COG2957	Belongs to the agmatine deiminase family
LH23_RS04565	COG2271	Major facilitator Superfamily
LH23_RS04575	COG0800	Aldolase
LH23_RS04580	COG3734	2-keto-3-deoxy-galactonokinase
LH23_RS04585	COG2186	Transcriptional regulator
LH23_RS04590	COG0561	phosphatase activity
LH23_RS04595	COG3753	Protein conserved in bacteria
LH23_RS04610	COG0592	DNA-directed DNA polymerase activity
LH23_RS04625	COG0706	membrane insertase activity
LH23_RS04635	COG2091	lysine biosynthetic process via aminoadipic acid
LH23_RS04640	COG0431	NADPH-dependent FMN reductase
LH23_RS04645	COG2252	PERMEase
LH23_RS04650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LH23_RS04655	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS04660	COG0583	DNA-binding transcription factor activity
LH23_RS04665	COG1295	ribonuclease BN
LH23_RS04675	COG0477	Major facilitator Superfamily
LH23_RS04680	COG2982	Protein involved in outer membrane biogenesis
LH23_RS04685	COG2200	EAL domain
LH23_RS04690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LH23_RS04695	COG0612	Peptidase, M16
LH23_RS04705	COG2199	diguanylate cyclase activity
LH23_RS04705	COG2200	EAL domain
LH23_RS04710	COG0457	Tetratricopeptide repeat
LH23_RS04710	COG3118	belongs to the thioredoxin family
LH23_RS04715	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LH23_RS04720	COG1215	transferase activity, transferring glycosyl groups
LH23_RS04725	COG1215	transferase activity, transferring glycosyl groups
LH23_RS04750	COG2194	sulfuric ester hydrolase activity
LH23_RS04755	COG2885	chlorophyll binding
LH23_RS04760	COG0243	molybdopterin cofactor binding
LH23_RS04770	COG2818	Glycosylase
LH23_RS04775	COG2223	nitrite transmembrane transporter activity
LH23_RS04780	COG1368	sulfuric ester hydrolase activity
LH23_RS04785	COG2194	sulfuric ester hydrolase activity
LH23_RS04790	COG0747	negative chemotaxis
LH23_RS04795	COG0601	transmembrane transport
LH23_RS04800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LH23_RS04805	COG0444	Belongs to the ABC transporter superfamily
LH23_RS04810	COG4608	Belongs to the ABC transporter superfamily
LH23_RS04815	COG2814	Major facilitator Superfamily
LH23_RS04820	COG0583	DNA-binding transcription factor activity
LH23_RS04825	COG1609	Transcriptional regulator
LH23_RS04835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LH23_RS04865	COG2944	sequence-specific DNA binding
LH23_RS04880	COG0752	glycyl-tRNA synthetase alpha subunit
LH23_RS04890	COG3274	enterobacterial common antigen metabolic process
LH23_RS04915	COG1070	Carbohydrate kinase
LH23_RS04925	COG4213	ABC transporter substrate-binding protein
LH23_RS04935	COG4214	carbohydrate transport
LH23_RS04940	COG1609	Transcriptional regulator
LH23_RS04940	COG2207	Transcriptional regulator
LH23_RS04945	COG2992	FlgJ-related protein
LH23_RS04955	COG0366	Alpha amylase catalytic
LH23_RS04960	COG3977	Valine--pyruvate aminotransferase
LH23_RS04965	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LH23_RS04970	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LH23_RS04975	COG3383	formate dehydrogenase (NAD+) activity
LH23_RS04980	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LH23_RS04985	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LH23_RS04995	COG3260	NADH ubiquinone oxidoreductase 20
LH23_RS05000	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LH23_RS05005	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LH23_RS05005	COG3261	NADH dehydrogenase
LH23_RS05010	COG0650	Formate hydrogenlyase subunit 4
LH23_RS05015	COG0651	ATP synthesis coupled electron transport
LH23_RS05020	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LH23_RS05030	COG0375	protein maturation
LH23_RS05035	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LH23_RS05040	COG0298	carbon dioxide binding
LH23_RS05045	COG0409	Hydrogenase expression formation protein
LH23_RS05050	COG0309	Hydrogenase expression formation protein (HypE)
LH23_RS05060	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LH23_RS05080	COG0784	Response regulator, receiver
LH23_RS05080	COG0835	chemotaxis
LH23_RS05090	COG2258	MOSC domain
LH23_RS05095	COG0704	Plays a role in the regulation of phosphate uptake
LH23_RS05100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LH23_RS05105	COG0581	inorganic phosphate transmembrane transporter activity
LH23_RS05110	COG0573	inorganic phosphate transmembrane transporter activity
LH23_RS05115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LH23_RS05130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LH23_RS05145	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LH23_RS05155	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LH23_RS05160	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LH23_RS05180	COG3312	ion transport
LH23_RS05195	COG0716	FMN binding
LH23_RS05200	COG1522	sequence-specific DNA binding
LH23_RS05230	COG1129	ABC transporter
LH23_RS05235	COG1172	Belongs to the binding-protein-dependent transport system permease family
LH23_RS05245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LH23_RS05250	COG1609	Transcriptional regulator
LH23_RS05255	COG0477	Major facilitator Superfamily
LH23_RS05260	COG2186	Transcriptional regulator
LH23_RS05285	COG1763	Mo-molybdopterin cofactor biosynthetic process
LH23_RS05290	COG0746	molybdenum cofactor guanylyltransferase activity
LH23_RS05295	COG3084	Protein conserved in bacteria
LH23_RS05300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LH23_RS05310	COG0204	Acyl-transferase
LH23_RS05315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LH23_RS05315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LH23_RS05325	COG3078	GTPase activator activity
LH23_RS05330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LH23_RS05335	COG2204	response regulator
LH23_RS05340	COG3852	Histidine kinase
LH23_RS05345	COG0174	glutamine synthetase
LH23_RS05355	COG1011	Hydrolase
LH23_RS05370	COG0456	acetyltransferase
LH23_RS05375	COG2982	Protein involved in outer membrane biogenesis
LH23_RS05380	COG2233	PERMEase
LH23_RS05385	COG0786	glutamate:sodium symporter activity
LH23_RS05390	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LH23_RS05395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LH23_RS05400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LH23_RS05410	COG0194	GDP metabolic process
LH23_RS05420	COG2860	membrane
LH23_RS05430	COG1561	YicC-like family, N-terminal region
LH23_RS05440	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LH23_RS05455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LH23_RS05465	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LH23_RS05485	COG1519	Transferase
LH23_RS05490	COG0438	transferase activity, transferring glycosyl groups
LH23_RS05495	COG0515	serine threonine protein kinase
LH23_RS05500	COG1442	glycosyl transferase family 8
LH23_RS05515	COG0859	PFAM glycosyl transferase family 9
LH23_RS05520	COG1216	Glycosyl transferase, family 2
LH23_RS05525	COG3307	-O-antigen
LH23_RS05530	COG0859	PFAM glycosyl transferase family 9
LH23_RS05555	COG2861	carbohydrate metabolic process
LH23_RS05560	COG4942	peptidase
LH23_RS05570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LH23_RS05575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LH23_RS05595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LH23_RS05600	COG2205	protein histidine kinase activity
LH23_RS05605	COG0745	RESPONSE REGULATOR receiver
LH23_RS05610	COG3678	ATP-independent chaperone mediated protein folding
LH23_RS05635	COG0149	triose-phosphate isomerase activity
LH23_RS05645	COG3152	Membrane
LH23_RS05655	COG1494	fructose-1,6-bisphosphatase
LH23_RS05660	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LH23_RS05670	COG3074	FtsZ-dependent cytokinesis
LH23_RS05680	COG1575	Belongs to the MenA family. Type 1 subfamily
LH23_RS05695	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LH23_RS05700	COG1609	Transcriptional regulator
LH23_RS05705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LH23_RS05710	COG0254	rRNA binding
LH23_RS05720	COG0626	cystathionine gamma-synthase activity
LH23_RS05725	COG0460	homoserine dehydrogenase
LH23_RS05725	COG0527	aspartate kinase activity
LH23_RS05735	COG2194	sulfuric ester hydrolase activity
LH23_RS05750	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LH23_RS05765	COG0165	Argininosuccinate lyase
LH23_RS05770	COG0583	DNA-binding transcription factor activity
LH23_RS05795	COG4206	TonB-dependent receptor
LH23_RS05840	COG3085	chromosome segregation
LH23_RS05845	COG0606	chelatase, subunit chli
LH23_RS05855	COG3978	acetolactate synthase activity
LH23_RS05875	COG0583	DNA-binding transcription factor activity
LH23_RS05905	COG0248	Ppx GppA phosphatase
LH23_RS05915	COG3118	belongs to the thioredoxin family
LH23_RS05920	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LH23_RS05925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LH23_RS05935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LH23_RS05940	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LH23_RS05945	COG0456	acetyltransferase
LH23_RS05950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LH23_RS05955	COG2244	polysaccharide biosynthetic process
LH23_RS06005	COG3071	HemY protein
LH23_RS06010	COG2959	enzyme of heme biosynthesis
LH23_RS06055	COG1011	Hydrolase
LH23_RS06060	COG0210	DNA helicase
LH23_RS06065	COG0598	Magnesium transport protein CorA
LH23_RS06080	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LH23_RS06085	COG0514	ATP-dependent DNA helicase (RecQ)
LH23_RS06090	COG1280	lysine exporter protein (LysE YggA)
LH23_RS06095	COG1280	lysine exporter protein (LysE YggA)
LH23_RS06100	COG2267	carboxylic ester hydrolase activity
LH23_RS06105	COG0561	phosphatase activity
LH23_RS06115	COG0583	DNA-binding transcription factor activity
LH23_RS06125	COG0412	Dienelactone hydrolase
LH23_RS06135	COG1322	Protein conserved in bacteria
LH23_RS06150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LH23_RS06160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LH23_RS06165	COG0805	protein transport
LH23_RS06210	COG1739	Uncharacterized protein family UPF0029
LH23_RS06220	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LH23_RS06250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LH23_RS06290	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LH23_RS06295	COG0250	Participates in transcription elongation, termination and antitermination
LH23_RS06310	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LH23_RS06335	COG2207	Transcriptional regulator
LH23_RS06335	COG3708	Transcriptional regulator
LH23_RS06340	COG1447	Phosphotransferase system cellobiose-specific component IIA
LH23_RS06360	COG2104	thiamine diphosphate biosynthetic process
LH23_RS06365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LH23_RS06380	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LH23_RS06415	COG0151	Belongs to the GarS family
LH23_RS06450	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LH23_RS06470	COG0646	methionine synthase
LH23_RS06470	COG1410	methionine synthase
LH23_RS06475	COG1283	sodium-dependent phosphate transmembrane transporter activity
LH23_RS06495	COG4650	regulator
LH23_RS06505	COG1690	Belongs to the RtcB family
LH23_RS06510	COG3541	Predicted nucleotidyltransferase
LH23_RS06515	COG0527	aspartate kinase activity
LH23_RS06540	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LH23_RS06550	COG3833	ABC-type maltose transport systems, permease component
LH23_RS06570	COG4580	involved in the transport of maltose and maltodextrins
LH23_RS06580	COG3161	chorismate lyase activity
LH23_RS06595	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LH23_RS06605	COG0534	Mate efflux family protein
LH23_RS06610	COG3237	CsbD-like
LH23_RS06615	COG0735	belongs to the Fur family
LH23_RS06630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LH23_RS06650	COG1448	Aminotransferase
LH23_RS06655	COG3700	Belongs to the class B bacterial acid phosphatase family
LH23_RS06660	COG2315	Protein conserved in bacteria
LH23_RS06685	COG0076	glutamate decarboxylase activity
LH23_RS06690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LH23_RS06695	COG0583	DNA-binding transcription factor activity
LH23_RS06700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LH23_RS06710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LH23_RS06725	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LH23_RS06740	COG0789	Transcriptional regulator
LH23_RS06750	COG2252	PERMEase
LH23_RS06755	COG0025	NhaP-type Na H and K H
LH23_RS06760	COG0583	DNA-binding transcription factor activity
LH23_RS06765	COG1380	Effector of murein hydrolase LrgA
LH23_RS06770	COG1346	cytolysis
LH23_RS06775	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LH23_RS06780	COG3162	membrane
LH23_RS06785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LH23_RS06790	COG1301	dicarboxylic acid transport
LH23_RS06795	COG3383	formate dehydrogenase (NAD+) activity
LH23_RS06800	COG3383	formate dehydrogenase (NAD+) activity
LH23_RS06830	COG1172	Belongs to the binding-protein-dependent transport system permease family
LH23_RS06845	COG1940	carbohydrate kinase activity
LH23_RS06850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LH23_RS06855	COG1172	Belongs to the binding-protein-dependent transport system permease family
LH23_RS06860	COG1129	ABC transporter
LH23_RS06865	COG1879	ABC-type sugar transport system periplasmic component
LH23_RS06870	COG1737	Transcriptional regulator
LH23_RS06875	COG0698	ribose 5-phosphate isomerase
LH23_RS06885	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LH23_RS06890	COG0456	acetyltransferase
LH23_RS06895	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LH23_RS06900	COG3454	Phosphonate metabolism
LH23_RS06905	COG4778	phosphonate C-P lyase system protein PhnL
LH23_RS06910	COG4107	phosphonate C-P lyase system protein PhnK
LH23_RS06915	COG3627	carbon phosphorus lyase activity
LH23_RS06920	COG3626	phosphonate metabolism
LH23_RS06925	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LH23_RS06930	COG3624	Phosphonate C-P lyase system protein PhnG
LH23_RS06935	COG2188	Transcriptional regulator
LH23_RS06940	COG2764	glyoxalase bleomycin resistance protein dioxygenase
LH23_RS06945	COG2824	Alkylphosphonate utilization operon protein PhnA
LH23_RS06955	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LH23_RS06965	COG1733	regulation of RNA biosynthetic process
LH23_RS06970	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS06985	COG2723	6-phospho-beta-galactosidase activity
LH23_RS06990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LH23_RS07000	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LH23_RS07010	COG1737	Transcriptional regulator
LH23_RS07015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LH23_RS07020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LH23_RS07025	COG1121	(ABC) transporter
LH23_RS07035	COG0625	glutathione transferase activity
LH23_RS07050	COG3721	Heme iron utilization protein
LH23_RS07060	COG0596	Alpha beta hydrolase
LH23_RS07095	COG1309	transcriptional regulator
LH23_RS07110	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LH23_RS07115	COG1027	Aspartate ammonia-lyase
LH23_RS07120	COG3030	protein affecting phage T7 exclusion by the F plasmid
LH23_RS07140	COG1509	lysine 2,3-aminomutase activity
LH23_RS07145	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LH23_RS07150	COG5510	response to toxic substance
LH23_RS07155	COG5510	response to toxic substance
LH23_RS07165	COG2076	Multidrug Resistance protein
LH23_RS07180	COG0583	DNA-binding transcription factor activity
LH23_RS07185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LH23_RS07190	COG2207	Transcriptional regulator
LH23_RS07205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LH23_RS07210	COG1053	succinate dehydrogenase
LH23_RS07220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LH23_RS07220	COG2169	Transcriptional regulator
LH23_RS07230	COG1335	isochorismatase
LH23_RS07245	COG1280	lysine exporter protein (LysE YggA)
LH23_RS07255	COG0312	modulator of DNA gyrase
LH23_RS07265	COG0110	maltose O-acetyltransferase activity
LH23_RS07295	COG0679	Auxin Efflux Carrier
LH23_RS07305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LH23_RS07340	COG3964	amidohydrolase
LH23_RS07360	COG3711	transcriptional antiterminator
LH23_RS07360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS07365	COG2823	Periplasmic or secreted lipoprotein
LH23_RS07370	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LH23_RS07375	COG0792	nuclease activity
LH23_RS07385	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LH23_RS07400	COG0191	fructose-bisphosphate aldolase activity
LH23_RS07405	COG2222	sugar isomerase
LH23_RS07415	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS07420	COG3716	PTS system mannose fructose sorbose family IID component
LH23_RS07430	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LH23_RS07440	COG1349	DNA-binding transcription factor activity
LH23_RS07445	COG0456	acetyltransferase
LH23_RS07450	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LH23_RS07460	COG2223	nitrite transmembrane transporter activity
LH23_RS07470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LH23_RS07475	COG0463	Glycosyl transferase, family 2
LH23_RS07480	COG1741	Belongs to the pirin family
LH23_RS07485	COG0583	DNA-binding transcription factor activity
LH23_RS07490	COG3264	Mechanosensitive ion channel
LH23_RS07490	COG1511	domain protein
LH23_RS07530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LH23_RS07530	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LH23_RS07535	COG0802	atpase or kinase
LH23_RS07550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LH23_RS07555	COG1923	regulation of RNA biosynthetic process
LH23_RS07560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LH23_RS07565	COG0330	HflC and HflK could
LH23_RS07570	COG0330	HflC and HflK could
LH23_RS07575	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LH23_RS07590	COG0557	exoribonuclease II activity
LH23_RS07600	COG1960	acyl-CoA dehydrogenase activity
LH23_RS07610	COG3650	response to hydrogen peroxide
LH23_RS07615	COG1073	alpha beta
LH23_RS07635	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LH23_RS07645	COG3061	Opacity-associated protein A
LH23_RS07650	COG0545	Peptidyl-prolyl cis-trans isomerase
LH23_RS07655	COG1113	amino acid transport
LH23_RS07665	COG0840	transmembrane signaling receptor activity
LH23_RS07670	COG0697	spore germination
LH23_RS07680	COG0702	epimerase
LH23_RS07685	COG1733	regulation of RNA biosynthetic process
LH23_RS07695	COG1218	3'(2'),5'-bisphosphate nucleotidase
LH23_RS07700	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LH23_RS07710	COG1253	flavin adenine dinucleotide binding
LH23_RS07730	COG0729	surface antigen
LH23_RS07735	COG2911	Protein conserved in bacteria
LH23_RS07740	COG2105	PFAM AIG2 family protein
LH23_RS07760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LH23_RS07765	COG3152	Membrane
LH23_RS07770	COG0435	Glutathione S-transferase
LH23_RS07775	COG2259	Doxx family
LH23_RS07785	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LH23_RS07790	COG4575	ribosome binding
LH23_RS07795	COG1422	Protein of unknown function (DUF1090)
LH23_RS07805	COG0586	Pfam SNARE associated Golgi protein
LH23_RS07810	COG2186	Transcriptional regulator
LH23_RS07815	COG2271	Major facilitator Superfamily
LH23_RS07825	COG2721	sulfolactate sulfo-lyase activity
LH23_RS07840	COG1349	DNA-binding transcription factor activity
LH23_RS07845	COG0698	ribose 5-phosphate isomerase
LH23_RS07850	COG3775	system Galactitol-specific IIC component
LH23_RS07855	COG3414	Phosphotransferase system galactitol-specific IIB component
LH23_RS07860	COG2213	PTS system mannitol-specific
LH23_RS07860	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS07865	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LH23_RS07870	COG0673	inositol 2-dehydrogenase activity
LH23_RS07875	COG1451	nucleotide metabolic process
LH23_RS07885	COG0446	pyridine nucleotide-disulphide oxidoreductase
LH23_RS07885	COG1902	pentaerythritol trinitrate reductase activity
LH23_RS07895	COG2205	protein histidine kinase activity
LH23_RS07905	COG0596	Alpha beta hydrolase
LH23_RS07920	COG1129	ABC transporter
LH23_RS07925	COG1172	Belongs to the binding-protein-dependent transport system permease family
LH23_RS07940	COG1830	Aldolase
LH23_RS07955	COG3706	GGDEF domain
LH23_RS07960	COG4608	Belongs to the ABC transporter superfamily
LH23_RS07965	COG0444	Belongs to the ABC transporter superfamily
LH23_RS07970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LH23_RS07975	COG0601	transmembrane transport
LH23_RS07980	COG0747	negative chemotaxis
LH23_RS07985	COG0477	Major facilitator Superfamily
LH23_RS07990	COG0840	transmembrane signaling receptor activity
LH23_RS08005	COG3493	citrate carrier protein
LH23_RS08010	COG0179	Fumarylacetoacetate (FAA) hydrolase
LH23_RS08020	COG3052	prosthetic group binding
LH23_RS08040	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LH23_RS08045	COG2130	NADP-dependent
LH23_RS08050	COG1278	Cold shock
LH23_RS08060	COG2186	Transcriptional regulator
LH23_RS08095	COG3038	cytochrome b561
LH23_RS08100	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LH23_RS08115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LH23_RS08125	COG2188	Transcriptional regulator
LH23_RS08135	COG2723	6-phospho-beta-galactosidase activity
LH23_RS08145	COG0840	transmembrane signaling receptor activity
LH23_RS08170	COG0358	DNA primase activity
LH23_RS08175	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LH23_RS08185	COG0134	indole-3-glycerol-phosphate synthase activity
LH23_RS08200	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LH23_RS08215	COG4991	sh3 domain protein
LH23_RS08220	COG3025	triphosphatase activity
LH23_RS08240	COG2252	PERMEase
LH23_RS08245	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LH23_RS08265	COG1764	response to oxidative stress
LH23_RS08270	COG1846	Transcriptional regulator
LH23_RS08280	COG2966	Psort location CytoplasmicMembrane, score
LH23_RS08290	COG2207	Transcriptional regulator
LH23_RS08295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LH23_RS08305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LH23_RS08310	COG4114	ferric iron reductase
LH23_RS08315	COG3706	GGDEF domain
LH23_RS08345	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LH23_RS08350	COG0456	acetyltransferase
LH23_RS08355	COG1011	Hydrolase
LH23_RS08365	COG2823	Periplasmic or secreted lipoprotein
LH23_RS08370	COG4667	esterase of the alpha-beta hydrolase superfamily
LH23_RS08375	COG0084	hydrolase, TatD family'
LH23_RS08380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LH23_RS08410	COG3726	membrane protein affecting hemolysin expression
LH23_RS08415	COG0560	Phosphoserine phosphatase
LH23_RS08420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LH23_RS08430	COG0488	(ABC) transporter
LH23_RS08435	COG0741	lytic transglycosylase activity
LH23_RS08455	COG3708	Transcriptional regulator
LH23_RS08455	COG2207	Transcriptional regulator
LH23_RS08460	COG3045	CreA protein
LH23_RS08470	COG0747	negative chemotaxis
LH23_RS08480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LH23_RS08490	COG2936	dipeptidyl-peptidase activity
LH23_RS08495	COG0745	RESPONSE REGULATOR receiver
LH23_RS08500	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LH23_RS08505	COG0460	homoserine dehydrogenase
LH23_RS08505	COG0527	aspartate kinase activity
LH23_RS08515	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LH23_RS08525	COG3022	response to hydroperoxide
LH23_RS08530	COG1115	amino acid carrier protein
LH23_RS08535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LH23_RS08540	COG0521	Mo-molybdopterin cofactor biosynthetic process
LH23_RS08550	COG1584	GPR1 FUN34 yaaH family protein
LH23_RS08555	COG0443	Heat shock 70 kDa protein
LH23_RS08570	COG0583	DNA-binding transcription factor activity
LH23_RS08580	COG0196	riboflavin kinase activity
LH23_RS08595	COG1047	Peptidyl-prolyl cis-trans
LH23_RS08615	COG0505	Belongs to the CarA family
LH23_RS08635	COG0475	glutathione-regulated potassium exporter activity
LH23_RS08635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LH23_RS08645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LH23_RS08650	COG2967	ApaG domain
LH23_RS08660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LH23_RS08675	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LH23_RS08680	COG0564	pseudouridine synthase activity
LH23_RS08690	COG0417	DNA replication proofreading
LH23_RS08695	COG0586	Pfam SNARE associated Golgi protein
LH23_RS08705	COG1178	ABC-type Fe3 transport system permease component
LH23_RS08725	COG2814	Major facilitator Superfamily
LH23_RS08755	COG0583	DNA-binding transcription factor activity
LH23_RS08760	COG0028	Belongs to the TPP enzyme family
LH23_RS08790	COG0768	penicillin binding
LH23_RS08800	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LH23_RS08810	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LH23_RS08815	COG0772	Belongs to the SEDS family
LH23_RS08840	COG0849	cell division
LH23_RS08845	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LH23_RS08870	COG0494	nUDIX hydrolase
LH23_RS08895	COG1459	type II secretion system
LH23_RS08900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LH23_RS08905	COG4969	Belongs to the N-Me-Phe pilin family
LH23_RS08920	COG3725	Membrane protein required for beta-lactamase induction
LH23_RS08935	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LH23_RS08940	COG0508	dehydrogenase complex catalyzes the overall conversion of
LH23_RS08945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LH23_RS08965	COG2132	Multicopper oxidase
LH23_RS08970	COG4993	Dehydrogenase
LH23_RS08975	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LH23_RS08980	COG0288	reversible hydration of carbon dioxide
LH23_RS08985	COG1131	(ABC) transporter
LH23_RS08990	COG0842	Transport permease protein
LH23_RS08995	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS09000	COG0726	polysaccharide deacetylase
LH23_RS09020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LH23_RS09025	COG0617	tRNA 3'-terminal CCA addition
LH23_RS09045	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LH23_RS09050	COG1643	Atp-dependent helicase
LH23_RS09055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LH23_RS09060	COG4774	siderophore transport
LH23_RS09065	COG1120	ATPase activity
LH23_RS09070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LH23_RS09090	COG0316	Belongs to the HesB IscA family
LH23_RS09095	COG2860	membrane
LH23_RS09145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LH23_RS09155	COG0233	cytoplasmic translational termination
LH23_RS09160	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LH23_RS09170	COG0575	Belongs to the CDS family
LH23_RS09175	COG0750	zinc metalloprotease
LH23_RS09190	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LH23_RS09195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LH23_RS09205	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LH23_RS09210	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LH23_RS09225	COG1982	Orn Lys Arg decarboxylase major
LH23_RS09230	COG0346	lactoylglutathione lyase activity
LH23_RS09235	COG0037	tRNA processing
LH23_RS09245	COG4568	rho-dependent transcription termination
LH23_RS09260	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LH23_RS09265	COG3015	lipoprotein NlpE involved in copper resistance
LH23_RS09275	COG1720	tRNA m6t6A37 methyltransferase activity
LH23_RS09285	COG1464	Belongs to the NlpA lipoprotein family
LH23_RS09290	COG2011	ABC-type metal ion transport system permease component
LH23_RS09295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LH23_RS09300	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LH23_RS09330	COG0656	L-ascorbic acid biosynthetic process
LH23_RS09335	COG0583	DNA-binding transcription factor activity
LH23_RS09340	COG2814	Major facilitator Superfamily
LH23_RS09350	COG2226	methyltransferase
LH23_RS09355	COG0741	lytic transglycosylase activity
LH23_RS09355	COG1388	LysM domain
LH23_RS09365	COG2226	methyltransferase
LH23_RS09370	COG0328	RNA-DNA hybrid ribonuclease activity
LH23_RS09375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LH23_RS09390	COG1953	Uracil, thiamine, allantoin
LH23_RS09435	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LH23_RS09445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LH23_RS09450	COG1960	acyl-CoA dehydrogenase activity
LH23_RS09460	COG0121	glutamine amidotransferase
LH23_RS09465	COG3034	peptidoglycan biosynthetic process
LH23_RS09475	COG2195	Cleaves the N-terminal amino acid of tripeptides
LH23_RS09495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LH23_RS09505	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LH23_RS09515	COG0582	viral genome integration into host DNA
LH23_RS09540	COG3423	Transcriptional regulator
LH23_RS09570	COG3539	Fimbrial protein
LH23_RS09575	COG3121	Chaperone
LH23_RS09580	COG3188	usher protein
LH23_RS09585	COG3539	Fimbrial protein
LH23_RS09590	COG3539	Fimbrial protein
LH23_RS09595	COG3539	Fimbrial protein
LH23_RS09610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LH23_RS09615	COG1696	Membrane protein involved in D-alanine export
LH23_RS09645	COG3443	Belongs to the bacterial solute-binding protein 9 family
LH23_RS09660	COG4566	intracellular signal transduction
LH23_RS09665	COG4191	Histidine kinase
LH23_RS09670	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LH23_RS09670	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LH23_RS09690	COG4565	transcriptional regulatory protein
LH23_RS09695	COG3290	protein histidine kinase activity
LH23_RS09705	COG4774	siderophore transport
LH23_RS09710	COG4607	ABC-type enterochelin transport system periplasmic component
LH23_RS09715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LH23_RS09725	COG4608	Belongs to the ABC transporter superfamily
LH23_RS09730	COG0444	Belongs to the ABC transporter superfamily
LH23_RS09745	COG0747	negative chemotaxis
LH23_RS09750	COG0346	lactoylglutathione lyase activity
LH23_RS09755	COG1113	amino acid transport
LH23_RS09770	COG0697	spore germination
LH23_RS09775	COG2199	diguanylate cyclase activity
LH23_RS09775	COG2203	Gaf domain
LH23_RS09780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LH23_RS09785	COG1560	Kdo2-lipid A biosynthetic process
LH23_RS09795	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LH23_RS09800	COG2814	Major facilitator Superfamily
LH23_RS09805	COG1566	PFAM secretion protein HlyD family protein
LH23_RS09810	COG1846	Transcriptional regulator
LH23_RS09830	COG1181	Belongs to the D-alanine--D-alanine ligase family
LH23_RS09835	COG2814	Major facilitator Superfamily
LH23_RS09845	COG1785	Belongs to the alkaline phosphatase family
LH23_RS09855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LH23_RS09860	COG1671	Belongs to the UPF0178 family
LH23_RS09865	COG3416	Protein conserved in bacteria
LH23_RS09875	COG4126	flavin adenine dinucleotide binding
LH23_RS09885	COG2974	May be involved in recombination
LH23_RS09890	COG1940	carbohydrate kinase activity
LH23_RS09895	COG0419	ATPase involved in DNA repair
LH23_RS09900	COG0420	3'-5' exonuclease activity
LH23_RS09910	COG5002	protein histidine kinase activity
LH23_RS09915	COG1114	Component of the transport system for branched-chain amino acids
LH23_RS09925	COG0366	Alpha amylase catalytic
LH23_RS09930	COG0583	DNA-binding transcription factor activity
LH23_RS09935	COG1335	isochorismatase
LH23_RS09945	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LH23_RS09950	COG0450	alkyl hydroperoxide reductase
LH23_RS09960	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LH23_RS09970	COG1862	Preprotein translocase
LH23_RS09975	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LH23_RS09980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LH23_RS09995	COG3248	Nucleoside-binding outer membrane protein
LH23_RS10000	COG4238	major outer membrane lipoprotein
LH23_RS10010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LH23_RS10010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LH23_RS10020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LH23_RS10025	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LH23_RS10030	COG0667	Aldo Keto reductase
LH23_RS10040	COG0142	geranyltranstransferase activity
LH23_RS10060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LH23_RS10070	COG2814	Major facilitator Superfamily
LH23_RS10080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LH23_RS10085	COG1845	cytochrome c oxidase, subunit III
LH23_RS10090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LH23_RS10095	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LH23_RS10100	COG0443	Heat shock 70 kDa protein
LH23_RS10120	COG1053	succinate dehydrogenase
LH23_RS10125	COG2223	nitrite transmembrane transporter activity
LH23_RS10130	COG3056	Lipoprotein
LH23_RS10135	COG0271	Belongs to the BolA IbaG family
LH23_RS10155	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LH23_RS10160	COG0776	regulation of translation
LH23_RS10165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LH23_RS10170	COG1555	photosystem II stabilization
LH23_RS10175	COG0824	Thioesterase
LH23_RS10185	COG4533	DNA binding
LH23_RS10190	COG0561	phosphatase activity
LH23_RS10200	COG1522	sequence-specific DNA binding
LH23_RS10205	COG1132	(ABC) transporter
LH23_RS10210	COG1132	(ABC) transporter
LH23_RS10215	COG0347	Belongs to the P(II) protein family
LH23_RS10220	COG0004	ammonium transporteR
LH23_RS10225	COG1946	Acyl-CoA thioesterase
LH23_RS10230	COG3126	Type III secretion system lipoprotein chaperone (YscW)
LH23_RS10235	COG3695	enzyme binding
LH23_RS10245	COG1522	sequence-specific DNA binding
LH23_RS10260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LH23_RS10265	COG2364	Membrane
LH23_RS10280	COG4771	TonB-dependent receptor
LH23_RS10285	COG1966	Carbon starvation protein
LH23_RS10290	COG2879	small protein
LH23_RS10295	COG0028	Belongs to the TPP enzyme family
LH23_RS10300	COG0440	acetolactate synthase activity
LH23_RS10305	COG3657	addiction module killer protein
LH23_RS10320	COG2186	Transcriptional regulator
LH23_RS10340	COG0583	DNA-binding transcription factor activity
LH23_RS10345	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LH23_RS10350	COG2885	chlorophyll binding
LH23_RS10370	COG3220	belongs to the UPF0276 family
LH23_RS10390	COG2864	formate dehydrogenase
LH23_RS10395	COG0437	4 iron, 4 sulfur cluster binding
LH23_RS10400	COG3383	formate dehydrogenase (NAD+) activity
LH23_RS10400	COG0243	molybdopterin cofactor binding
LH23_RS10405	COG3383	formate dehydrogenase (NAD+) activity
LH23_RS10405	COG0243	molybdopterin cofactor binding
LH23_RS10440	COG0583	DNA-binding transcription factor activity
LH23_RS10445	COG0666	response to abiotic stimulus
LH23_RS10450	COG0402	S-adenosylhomocysteine deaminase activity
LH23_RS10455	COG0589	response to stress
LH23_RS10465	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS10475	COG2733	membrane
LH23_RS10605	COG1609	Transcriptional regulator
LH23_RS10610	COG3250	beta-galactosidase activity
LH23_RS10615	COG2731	YhcH YjgK YiaL family protein
LH23_RS10620	COG0531	amino acid
LH23_RS10625	COG0531	amino acid
LH23_RS10675	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS10695	COG3121	Chaperone
LH23_RS10700	COG3188	usher protein
LH23_RS10710	COG3468	outer membrane autotransporter barrel domain protein
LH23_RS10715	COG2197	response regulator
LH23_RS10720	COG2205	protein histidine kinase activity
LH23_RS10720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LH23_RS10735	COG2197	response regulator
LH23_RS10750	COG2501	S4 domain
LH23_RS10755	COG1263	PTS System
LH23_RS10755	COG2190	(PTS) system
LH23_RS10755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LH23_RS10760	COG1609	Transcriptional regulator
LH23_RS10780	COG1684	flagellar biosynthetic protein fliR
LH23_RS10785	COG1987	bacterial-type flagellum assembly
LH23_RS10820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LH23_RS10880	COG1815	bacterial-type flagellum-dependent cell motility
LH23_RS10885	COG1558	bacterial-type flagellum-dependent cell motility
LH23_RS10905	COG4786	Flagellar basal body rod
LH23_RS10915	COG1706	bacterial-type flagellum-dependent cell motility
LH23_RS10925	COG4786	Flagellar basal body rod
LH23_RS10925	COG1256	bacterial-type flagellum assembly
LH23_RS10960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LH23_RS10965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LH23_RS10970	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LH23_RS10995	COG1191	sigma factor activity
LH23_RS11000	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LH23_RS11010	COG0791	NLP P60 protein
LH23_RS11020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LH23_RS11025	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS11030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LH23_RS11035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LH23_RS11060	COG1216	Glycosyl transferase, family 2
LH23_RS11070	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LH23_RS11070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LH23_RS11080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LH23_RS11110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LH23_RS11115	COG2610	gluconate transmembrane transporter activity
LH23_RS11120	COG3719	Belongs to the RNase T2 family
LH23_RS11125	COG3069	C4-dicarboxylate transmembrane transporter activity
LH23_RS11145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LH23_RS11150	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LH23_RS11165	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LH23_RS11170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LH23_RS11185	COG0583	DNA-binding transcription factor activity
LH23_RS11200	COG1686	Belongs to the peptidase S11 family
LH23_RS11205	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LH23_RS11210	COG0772	Belongs to the SEDS family
LH23_RS11215	COG0768	penicillin binding
LH23_RS11220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LH23_RS11225	COG0799	negative regulation of ribosome biogenesis
LH23_RS11235	COG1466	dna polymerase III delta subunit
LH23_RS11250	COG2888	peptidyl-tyrosine sulfation
LH23_RS11255	COG1126	abc transporter atp-binding protein
LH23_RS11260	COG0765	amino acid transport
LH23_RS11265	COG0765	amino acid transport
LH23_RS11280	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LH23_RS11285	COG4535	Mg2 and Co2 transporter CorC
LH23_RS11295	COG1702	phosphate starvation-inducible protein PhoH
LH23_RS11305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LH23_RS11345	COG0367	asparagine synthase
LH23_RS11350	COG0647	UMP catabolic process
LH23_RS11355	COG1940	carbohydrate kinase activity
LH23_RS11355	COG1846	Transcriptional regulator
LH23_RS11360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LH23_RS11370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LH23_RS11370	COG1263	PTS System
LH23_RS11370	COG2190	(PTS) system
LH23_RS11390	COG0735	belongs to the Fur family
LH23_RS11405	COG0596	Alpha beta hydrolase
LH23_RS11410	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LH23_RS11415	COG0033	Phosphoglucomutase
LH23_RS11425	COG0745	RESPONSE REGULATOR receiver
LH23_RS11430	COG2205	protein histidine kinase activity
LH23_RS11440	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LH23_RS11460	COG0415	Belongs to the DNA photolyase family
LH23_RS11470	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LH23_RS11475	COG1984	allophanate hydrolase subunit 2
LH23_RS11485	COG0372	Belongs to the citrate synthase family
LH23_RS11490	COG2009	succinate dehydrogenase
LH23_RS11495	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LH23_RS11500	COG1053	succinate dehydrogenase
LH23_RS11505	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LH23_RS11510	COG0567	Dehydrogenase, E1 component
LH23_RS11515	COG0508	dehydrogenase complex catalyzes the overall conversion of
LH23_RS11525	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LH23_RS11530	COG1271	oxidase subunit
LH23_RS11535	COG1294	oxidase, subunit
LH23_RS11540	COG3790	cyd operon protein YbgE
LH23_RS11545	COG0824	Thioesterase
LH23_RS11550	COG0811	peptide transport
LH23_RS11555	COG0848	biopolymer transport protein
LH23_RS11560	COG3064	Membrane
LH23_RS11560	COG3064	Membrane
LH23_RS11570	COG2885	chlorophyll binding
LH23_RS11575	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LH23_RS11610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LH23_RS11615	COG0588	phosphoglycerate mutase activity
LH23_RS11620	COG2017	converts alpha-aldose to the beta-anomer
LH23_RS11630	COG1085	galactose-1-phosphate uridylyltransferase
LH23_RS11635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LH23_RS11640	COG1119	ATPase activity
LH23_RS11645	COG2005	Transcriptional regulator
LH23_RS11645	COG3585	molybdate ion transport
LH23_RS11650	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LH23_RS11660	COG0725	ABC transporter, periplasmic molybdate-binding protein
LH23_RS11665	COG4149	molybdate abc transporter
LH23_RS11670	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LH23_RS11675	COG0561	phosphatase activity
LH23_RS11685	COG4677	pectinesterase activity
LH23_RS11695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LH23_RS11715	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LH23_RS11745	COG0521	Mo-molybdopterin cofactor biosynthetic process
LH23_RS11755	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LH23_RS11760	COG0314	molybdopterin synthase activity
LH23_RS11765	COG0670	Belongs to the BI1 family
LH23_RS11775	COG0842	Transport permease protein
LH23_RS11780	COG0842	Transport permease protein
LH23_RS11785	COG1131	(ABC) transporter
LH23_RS11790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LH23_RS11795	COG1309	transcriptional regulator
LH23_RS11800	COG0513	Belongs to the DEAD box helicase family
LH23_RS11805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LH23_RS11815	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LH23_RS11830	COG2723	6-phospho-beta-galactosidase activity
LH23_RS11870	COG0586	Pfam SNARE associated Golgi protein
LH23_RS11880	COG1686	Belongs to the peptidase S11 family
LH23_RS11890	COG0277	FAD linked oxidase domain protein
LH23_RS11895	COG1472	Belongs to the glycosyl hydrolase 3 family
LH23_RS11915	COG0285	dihydrofolate synthase activity
LH23_RS11920	COG3485	protocatechuate 3,4-dioxygenase
LH23_RS11935	COG0174	glutamine synthetase
LH23_RS11940	COG1732	Glycine betaine
LH23_RS11945	COG1174	glycine betaine transport
LH23_RS11950	COG1125	glycine betaine transport
LH23_RS11955	COG1174	glycine betaine transport
LH23_RS11965	COG0789	Transcriptional regulator
LH23_RS11970	COG2850	peptidyl-arginine hydroxylation
LH23_RS12055	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LH23_RS12065	COG4794	Type iii secretion
LH23_RS12090	COG1157	protein secretion by the type III secretion system
LH23_RS12120	COG2197	response regulator
LH23_RS12150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LH23_RS12170	COG1446	asparaginase
LH23_RS12175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LH23_RS12185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LH23_RS12195	COG1126	abc transporter atp-binding protein
LH23_RS12200	COG0765	amino acid transport
LH23_RS12205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LH23_RS12220	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LH23_RS12225	COG2194	sulfuric ester hydrolase activity
LH23_RS12235	COG1321	iron dependent repressor
LH23_RS12240	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LH23_RS12245	COG0667	Aldo Keto reductase
LH23_RS12255	COG0561	phosphatase activity
LH23_RS12260	COG0738	Major facilitator superfamily
LH23_RS12265	COG3226	Transcriptional regulator
LH23_RS12295	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LH23_RS12300	COG2211	Major facilitator Superfamily
LH23_RS12305	COG0583	DNA-binding transcription factor activity
LH23_RS12320	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LH23_RS12325	COG3842	ATPase activity
LH23_RS12330	COG1176	ABC-type spermidine putrescine transport system, permease component I
LH23_RS12335	COG1177	transmembrane transport
LH23_RS12350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LH23_RS12355	COG4160	amino acid transport
LH23_RS12360	COG4215	(ABC) transporter
LH23_RS12365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LH23_RS12370	COG1126	abc transporter atp-binding protein
LH23_RS12385	COG3023	N-Acetylmuramoyl-L-alanine amidase
LH23_RS12390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LH23_RS12395	COG0702	epimerase
LH23_RS12400	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LH23_RS12405	COG0028	Belongs to the TPP enzyme family
LH23_RS12415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LH23_RS12420	COG1151	hydroxylamine reductase activity
LH23_RS12425	COG2431	L-lysine efflux transmembrane transporter activity
LH23_RS12430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LH23_RS12435	COG3593	DNA synthesis involved in DNA repair
LH23_RS12440	COG2990	Protein conserved in bacteria
LH23_RS12445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LH23_RS12455	COG1278	Cold shock
LH23_RS12465	COG0542	response to heat
LH23_RS12470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LH23_RS12480	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LH23_RS12485	COG4988	ABC transporter
LH23_RS12490	COG0492	ferredoxin-NADP+ reductase activity
LH23_RS12500	COG1178	ABC-type Fe3 transport system permease component
LH23_RS12500	COG1674	ftsk spoiiie
LH23_RS12510	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LH23_RS12520	COG0243	molybdopterin cofactor binding
LH23_RS12525	COG0437	4 iron, 4 sulfur cluster binding
LH23_RS12530	COG3302	dmso reductase anchor subunit
LH23_RS12535	COG0477	Major facilitator Superfamily
LH23_RS12540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LH23_RS12545	COG1882	Formate acetyltransferase
LH23_RS12550	COG2116	formate transmembrane transporter activity
LH23_RS12555	COG1944	ATP diphosphatase activity
LH23_RS12575	COG0539	negative regulation of cytoplasmic translation
LH23_RS12580	COG0776	regulation of translation
LH23_RS12585	COG2333	competence protein COMEC
LH23_RS12585	COG0658	competence protein
LH23_RS12600	COG3214	Protein conserved in bacteria
LH23_RS12615	COG3173	Aminoglycoside phosphotransferase
LH23_RS12620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LH23_RS12625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LH23_RS12635	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
LH23_RS12645	COG2989	Protein conserved in bacteria
LH23_RS12650	COG3108	Peptidase M15
LH23_RS12655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LH23_RS12660	COG1448	Aminotransferase
LH23_RS12665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LH23_RS12685	COG0308	aminopeptidase N
LH23_RS12695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LH23_RS12705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LH23_RS12710	COG0431	NADPH-dependent FMN reductase
LH23_RS12725	COG3217	Mosc domain protein beta barrel domain protein
LH23_RS12725	COG0633	Ferredoxin
LH23_RS12735	COG0488	(ABC) transporter
LH23_RS12740	COG2995	paraquat-inducible protein a
LH23_RS12745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LH23_RS12745	COG3008	intermembrane lipid transfer
LH23_RS12750	COG3009	Protein conserved in bacteria
LH23_RS12755	COG3842	ATPase activity
LH23_RS12760	COG1175	transmembrane transport
LH23_RS12775	COG1067	ATP-dependent peptidase activity
LH23_RS12785	COG2885	chlorophyll binding
LH23_RS12785	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LH23_RS12790	COG3070	regulator of competence-specific genes
LH23_RS12795	COG1289	transmembrane transporter activity
LH23_RS12800	COG3304	Inner membrane component domain
LH23_RS12805	COG0210	DNA helicase
LH23_RS12815	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LH23_RS12820	COG1832	CoA-binding protein
LH23_RS12835	COG1254	Belongs to the acylphosphatase family
LH23_RS12840	COG2920	part of a sulfur-relay system
LH23_RS12845	COG0670	Belongs to the BI1 family
LH23_RS12865	COG2963	transposase activity
LH23_RS12870	COG2801	Transposase and inactivated derivatives
LH23_RS12930	COG0745	RESPONSE REGULATOR receiver
LH23_RS12955	COG1129	ABC transporter
LH23_RS12960	COG1172	Belongs to the binding-protein-dependent transport system permease family
LH23_RS12965	COG1172	Belongs to the binding-protein-dependent transport system permease family
LH23_RS12975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LH23_RS13010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LH23_RS13015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LH23_RS13025	COG4221	oxidoreductase activity
LH23_RS13050	COG3729	General stress protein
LH23_RS13060	COG1309	transcriptional regulator
LH23_RS13065	COG3755	Protein conserved in bacteria
LH23_RS13070	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LH23_RS13070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LH23_RS13070	COG0506	proline dehydrogenase activity
LH23_RS13075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LH23_RS13085	COG2822	iron ion transport
LH23_RS13095	COG1702	phosphate starvation-inducible protein PhoH
LH23_RS13100	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LH23_RS13105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LH23_RS13110	COG1447	Phosphotransferase system cellobiose-specific component IIA
LH23_RS13115	COG2169	Transcriptional regulator
LH23_RS13115	COG1917	Cupin 2, conserved barrel domain protein
LH23_RS13120	COG1486	melibiose metabolic process
LH23_RS13165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LH23_RS13175	COG3381	protein complex oligomerization
LH23_RS13200	COG2197	response regulator
LH23_RS13235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LH23_RS13240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LH23_RS13250	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LH23_RS13265	COG2943	transferase activity, transferring hexosyl groups
LH23_RS13270	COG5645	(Lipo)protein
LH23_RS13285	COG1560	Kdo2-lipid A biosynthetic process
LH23_RS13295	COG2353	YceI-like domain
LH23_RS13300	COG3038	cytochrome b561
LH23_RS13335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LH23_RS13350	COG0728	peptidoglycan biosynthetic process
LH23_RS13375	COG1815	bacterial-type flagellum-dependent cell motility
LH23_RS13380	COG1558	bacterial-type flagellum-dependent cell motility
LH23_RS13390	COG1749	Flagellar hook protein flgE
LH23_RS13400	COG4786	Flagellar basal body rod
LH23_RS13420	COG1256	bacterial-type flagellum assembly
LH23_RS13435	COG3615	Tellurite resistance protein tehB
LH23_RS13440	COG3615	Tellurite resistance protein tehB
LH23_RS13445	COG1530	ribonuclease E activity
LH23_RS13450	COG0564	pseudouridine synthase activity
LH23_RS13455	COG0424	maF-like protein
LH23_RS13460	COG1399	metal-binding, possibly nucleic acid-binding protein
LH23_RS13465	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LH23_RS13480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LH23_RS13485	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS13490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LH23_RS13495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LH23_RS13500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LH23_RS13505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LH23_RS13510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LH23_RS13515	COG0470	DNA polymerase III
LH23_RS13520	COG0084	hydrolase, TatD family'
LH23_RS13525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LH23_RS13525	COG1263	PTS System
LH23_RS13530	COG0537	adenosine 5'-monophosphoramidase activity
LH23_RS13535	COG5633	Lipoprotein
LH23_RS13560	COG1252	NADH dehydrogenase
LH23_RS13565	COG3134	Outer membrane lipoprotein
LH23_RS13610	COG1309	transcriptional regulator
LH23_RS13620	COG1376	ErfK ybiS ycfS ynhG family protein
LH23_RS13620	COG1388	LysM domain
LH23_RS13625	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LH23_RS13630	COG4763	Acyl-transferase
LH23_RS13635	COG4591	ABC-type transport system involved in lipoprotein release permease component
LH23_RS13645	COG4591	ABC-type transport system involved in lipoprotein release permease component
LH23_RS13660	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LH23_RS13675	COG3842	ATPase activity
LH23_RS13705	COG3264	Mechanosensitive ion channel
LH23_RS13705	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LH23_RS13715	COG1840	ABC-type Fe3 transport system, periplasmic component
LH23_RS13720	COG4149	molybdate abc transporter
LH23_RS13725	COG3842	ATPase activity
LH23_RS13730	COG2850	peptidyl-arginine hydroxylation
LH23_RS13740	COG0745	RESPONSE REGULATOR receiver
LH23_RS13745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LH23_RS13770	COG1187	pseudouridine synthase activity
LH23_RS13775	COG0538	isocitrate dehydrogenase activity
LH23_RS13780	COG0488	(ABC) transporter
LH23_RS13790	COG0583	DNA-binding transcription factor activity
LH23_RS13795	COG1216	Glycosyl transferase, family 2
LH23_RS13795	COG1442	glycosyl transferase family 8
LH23_RS13805	COG1349	DNA-binding transcription factor activity
LH23_RS13810	COG0494	nUDIX hydrolase
LH23_RS13875	COG3189	MarR family transcriptional regulator
LH23_RS13885	COG0504	CTP synthase activity
LH23_RS13905	COG2807	transmembrane transport
LH23_RS13910	COG2207	Transcriptional regulator
LH23_RS13915	COG0840	transmembrane signaling receptor activity
LH23_RS13920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LH23_RS13930	COG0765	amino acid transport
LH23_RS13935	COG0765	amino acid transport
LH23_RS13940	COG2707	UPF0756 membrane protein
LH23_RS13945	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LH23_RS13950	COG0494	nUDIX hydrolase
LH23_RS13975	COG2200	EAL domain
LH23_RS13995	COG2766	serine protein kinase
LH23_RS14100	COG2963	transposase activity
LH23_RS14105	COG2801	Transposase and inactivated derivatives
LH23_RS14130	COG3713	MltA-interacting MipA family protein
LH23_RS14140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LH23_RS14150	COG3139	Protein of unknown function (DUF1315)
LH23_RS14160	COG1335	isochorismatase
LH23_RS14165	COG0252	asparaginase activity
LH23_RS14170	COG0616	signal peptide processing
LH23_RS14175	COG0778	Nitroreductase
LH23_RS14190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LH23_RS14200	COG0494	nUDIX hydrolase
LH23_RS14205	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LH23_RS14210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LH23_RS14215	COG2897	thiosulfate sulfurtransferase activity
LH23_RS14220	COG4136	ATPase activity
LH23_RS14225	COG4135	transport system, permease component
LH23_RS14230	COG4134	Bacterial extracellular solute-binding protein
LH23_RS14240	COG1764	response to oxidative stress
LH23_RS14250	COG0708	Exodeoxyribonuclease III
LH23_RS14260	COG3138	arginine N-succinyltransferase
LH23_RS14280	COG3678	ATP-independent chaperone mediated protein folding
LH23_RS14290	COG2986	histidine ammonia-lyase
LH23_RS14295	COG0322	excinuclease ABC activity
LH23_RS14310	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LH23_RS14320	COG1823	symporter activity
LH23_RS14325	COG1988	membrane-bound metal-dependent
LH23_RS14330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LH23_RS14340	COG3001	Fructosamine kinase
LH23_RS14350	COG1105	Belongs to the carbohydrate kinase PfkB family
LH23_RS14355	COG3137	Salt-induced outer membrane protein
LH23_RS14370	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LH23_RS14375	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LH23_RS14390	COG0072	phenylalanine-tRNA ligase activity
LH23_RS14390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LH23_RS14400	COG0456	acetyltransferase
LH23_RS14400	COG1846	Transcriptional regulator
LH23_RS14410	COG0386	Belongs to the glutathione peroxidase family
LH23_RS14420	COG0791	NLP P60 protein
LH23_RS14425	COG1609	Transcriptional regulator
LH23_RS14440	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LH23_RS14445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LH23_RS14450	COG4558	Periplasmic binding protein
LH23_RS14455	COG3720	iron ion transport
LH23_RS14465	COG4256	Hemin uptake protein
LH23_RS14480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LH23_RS14480	COG0574	Belongs to the PEP-utilizing enzyme family
LH23_RS14485	COG2382	esterase
LH23_RS14490	COG4774	siderophore transport
LH23_RS14495	COG2819	hydrolase of the alpha beta superfamily
LH23_RS14500	COG0628	permease
LH23_RS14505	COG0247	lactate metabolic process
LH23_RS14505	COG0277	FAD linked oxidase domain protein
LH23_RS14510	COG2050	protein possibly involved in aromatic compounds catabolism
LH23_RS14525	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LH23_RS14530	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LH23_RS14540	COG0316	Belongs to the HesB IscA family
LH23_RS14545	COG0719	Fe-S assembly protein
LH23_RS14550	COG0396	ATPase activity
LH23_RS14555	COG0719	Fe-S assembly protein
LH23_RS14565	COG2166	iron-sulfur cluster assembly
LH23_RS14570	COG1376	ErfK ybiS ycfS ynhG family protein
LH23_RS14595	COG0583	DNA-binding transcription factor activity
LH23_RS14605	COG0251	oxidation-reduction process
LH23_RS14625	COG0307	riboflavin synthase, alpha
LH23_RS14630	COG2723	6-phospho-beta-galactosidase activity
LH23_RS14635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LH23_RS14640	COG2814	Major facilitator Superfamily
LH23_RS14645	COG0583	DNA-binding transcription factor activity
LH23_RS14660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LH23_RS14665	COG0791	NLP P60 protein
LH23_RS14670	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LH23_RS14685	COG0346	lactoylglutathione lyase activity
LH23_RS14690	COG1902	pentaerythritol trinitrate reductase activity
LH23_RS14695	COG1309	transcriptional regulator
LH23_RS14700	COG2194	sulfuric ester hydrolase activity
LH23_RS14705	COG4989	oxidoreductase activity
LH23_RS14710	COG1289	transmembrane transporter activity
LH23_RS14715	COG1566	PFAM secretion protein HlyD family protein
LH23_RS14730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LH23_RS14735	COG1473	amidohydrolase
LH23_RS14740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LH23_RS14745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LH23_RS14760	COG1126	abc transporter atp-binding protein
LH23_RS14765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LH23_RS14775	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LH23_RS14780	COG3895	Periplasmic Protein
LH23_RS14800	COG0625	glutathione transferase activity
LH23_RS14805	COG3104	oligopeptide transport
LH23_RS14810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LH23_RS14820	COG4659	FMN binding
LH23_RS14855	COG0673	inositol 2-dehydrogenase activity
LH23_RS14870	COG0385	Bile acid
LH23_RS14875	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LH23_RS14885	COG2226	methyltransferase
LH23_RS14900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LH23_RS14905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LH23_RS14905	COG1263	PTS System
LH23_RS14910	COG1609	Transcriptional regulator
LH23_RS14930	COG5339	Protein conserved in bacteria
LH23_RS14940	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LH23_RS14940	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LH23_RS14955	COG2205	protein histidine kinase activity
LH23_RS14965	COG0745	RESPONSE REGULATOR receiver
LH23_RS14975	COG0531	amino acid
LH23_RS14985	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LH23_RS14990	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LH23_RS15000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LH23_RS15005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LH23_RS15010	COG2840	Smr protein MutS2
LH23_RS15015	COG0583	DNA-binding transcription factor activity
LH23_RS15020	COG5383	Protein conserved in bacteria
LH23_RS15030	COG0583	DNA-binding transcription factor activity
LH23_RS15035	COG0436	Aminotransferase
LH23_RS15060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LH23_RS15065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LH23_RS15070	COG1275	C4-dicarboxylate transporter malic acid transport protein
LH23_RS15075	COG0500	methyltransferase
LH23_RS15080	COG2195	Cleaves the N-terminal amino acid of tripeptides
LH23_RS15085	COG0747	negative chemotaxis
LH23_RS15090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LH23_RS15095	COG1486	melibiose metabolic process
LH23_RS15120	COG2207	Transcriptional regulator
LH23_RS15125	COG3135	benzoate transporter
LH23_RS15130	COG1396	sequence-specific DNA binding
LH23_RS15135	COG0826	peptidase U32
LH23_RS15140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LH23_RS15145	COG0463	Glycosyl transferase, family 2
LH23_RS15150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LH23_RS15150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LH23_RS15155	COG0726	polysaccharide deacetylase
LH23_RS15160	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LH23_RS15165	COG2076	Multidrug Resistance protein
LH23_RS15170	COG2076	Multidrug Resistance protein
LH23_RS15175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LH23_RS15185	COG0583	DNA-binding transcription factor activity
LH23_RS15195	COG1902	pentaerythritol trinitrate reductase activity
LH23_RS15205	COG1464	Belongs to the NlpA lipoprotein family
LH23_RS15210	COG2011	ABC-type metal ion transport system permease component
LH23_RS15215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LH23_RS15220	COG3275	phosphorelay sensor kinase activity
LH23_RS15230	COG0523	cobalamin synthesis protein
LH23_RS15235	COG2879	small protein
LH23_RS15240	COG1966	Carbon starvation protein
LH23_RS15255	COG3188	usher protein
LH23_RS15275	COG0457	Tetratricopeptide repeat
LH23_RS15280	COG0726	polysaccharide deacetylase
LH23_RS15280	COG1649	PFAM Uncharacterised BCR, COG1649
LH23_RS15285	COG1215	transferase activity, transferring glycosyl groups
LH23_RS15300	COG1280	lysine exporter protein (LysE YggA)
LH23_RS15310	COG3180	Ammonia monooxygenase
LH23_RS15335	COG0583	DNA-binding transcription factor activity
LH23_RS15345	COG0386	Belongs to the glutathione peroxidase family
LH23_RS15435	COG3158	transport of potassium into the cell
LH23_RS15450	COG0400	carboxylic ester hydrolase activity
LH23_RS15455	COG0628	permease
LH23_RS15460	COG2076	Multidrug Resistance protein
LH23_RS15470	COG5001	Diguanylate cyclase
LH23_RS15475	COG0740	serine-type endopeptidase activity
LH23_RS15480	COG0772	Belongs to the SEDS family
LH23_RS15485	COG3591	Belongs to the peptidase S1B family
LH23_RS15495	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LH23_RS15500	COG2814	Major facilitator Superfamily
LH23_RS15505	COG0583	DNA-binding transcription factor activity
LH23_RS15510	COG1940	carbohydrate kinase activity
LH23_RS15515	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LH23_RS15545	COG3381	protein complex oligomerization
LH23_RS15570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LH23_RS15570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LH23_RS15570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS15590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LH23_RS15615	COG3327	negative regulation of DNA-templated transcription, initiation
LH23_RS15620	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LH23_RS15630	COG1643	Atp-dependent helicase
LH23_RS15635	COG4122	O-methyltransferase activity
LH23_RS15640	COG0243	molybdopterin cofactor binding
LH23_RS15655	COG3300	MHYT domain
LH23_RS15655	COG5001	Diguanylate cyclase
LH23_RS15680	COG2885	chlorophyll binding
LH23_RS15765	COG0840	transmembrane signaling receptor activity
LH23_RS15770	COG4628	conserved protein (DUF2132)
LH23_RS15780	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LH23_RS15785	COG3038	cytochrome b561
LH23_RS15795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LH23_RS15805	COG1770	oligopeptidase
LH23_RS15820	COG0300	oxidoreductase activity
LH23_RS15870	COG3772	lysozyme
LH23_RS15910	COG4220	transposase activity
LH23_RS15940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LH23_RS15955	COG4221	oxidoreductase activity
LH23_RS15960	COG0339	signal peptide processing
LH23_RS15965	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LH23_RS16005	COG2207	Transcriptional regulator
LH23_RS16035	COG5455	response to cobalt ion
LH23_RS16070	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LH23_RS16070	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LH23_RS16070	COG1013	pyruvate-flavodoxin oxidoreductase activity
LH23_RS16070	COG0674	pyruvate-flavodoxin oxidoreductase activity
LH23_RS16080	COG3042	response to heat
LH23_RS16085	COG3187	Heat shock protein
LH23_RS16090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LH23_RS16095	COG2911	Protein conserved in bacteria
LH23_RS16105	COG3784	Protein of unknown function (DUF1318)
LH23_RS16110	COG2207	Transcriptional regulator
LH23_RS16115	COG1012	belongs to the aldehyde dehydrogenase family
LH23_RS16130	COG2274	protein secretion by the type I secretion system
LH23_RS16155	COG1012	belongs to the aldehyde dehydrogenase family
LH23_RS16155	COG2030	dehydratase
LH23_RS16160	COG3396	Phenylacetate-CoA oxygenase
LH23_RS16165	COG3460	Phenylacetate-CoA oxygenase
LH23_RS16170	COG3396	Phenylacetate-CoA oxygenase
LH23_RS16175	COG2151	metal-sulfur cluster biosynthetic enzyme
LH23_RS16180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LH23_RS16185	COG1024	Enoyl-CoA hydratase
LH23_RS16190	COG1024	Enoyl-CoA hydratase
LH23_RS16195	COG1250	3-hydroxyacyl-CoA dehydrogenase
LH23_RS16200	COG2050	protein possibly involved in aromatic compounds catabolism
LH23_RS16205	COG0183	Belongs to the thiolase family
LH23_RS16210	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LH23_RS16220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LH23_RS16230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LH23_RS16235	COG0601	transmembrane transport
LH23_RS16240	COG4166	transmembrane transport
LH23_RS16255	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LH23_RS16265	COG2076	Multidrug Resistance protein
LH23_RS16270	COG1215	transferase activity, transferring glycosyl groups
LH23_RS16275	COG4783	chaperone-mediated protein folding
LH23_RS16285	COG1294	oxidase, subunit
LH23_RS16290	COG1271	oxidase subunit
LH23_RS16310	COG0483	inositol monophosphate 1-phosphatase activity
LH23_RS16315	COG1609	Transcriptional regulator
LH23_RS16350	COG1175	transmembrane transport
LH23_RS16355	COG0395	ABC-type sugar transport system, permease component
LH23_RS16360	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LH23_RS16365	COG3842	ATPase activity
LH23_RS16370	COG1653	transport
LH23_RS16375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LH23_RS16380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LH23_RS16385	COG1234	tRNA 3'-trailer cleavage
LH23_RS16400	COG1012	belongs to the aldehyde dehydrogenase family
LH23_RS16405	COG1652	LysM domain
LH23_RS16415	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LH23_RS16460	COG0601	transmembrane transport
LH23_RS16465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LH23_RS16475	COG1802	Transcriptional regulator
LH23_RS16480	COG0626	cystathionine gamma-synthase activity
LH23_RS16490	COG1959	2 iron, 2 sulfur cluster binding
LH23_RS16495	COG1252	NADH dehydrogenase
LH23_RS16510	COG2841	Protein conserved in bacteria
LH23_RS16515	COG2375	cellular response to nickel ion
LH23_RS16540	COG0456	acetyltransferase
LH23_RS16545	COG4772	TonB-dependent receptor
LH23_RS16550	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LH23_RS16580	COG0745	RESPONSE REGULATOR receiver
LH23_RS16590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LH23_RS16605	COG0697	spore germination
LH23_RS16610	COG2315	Protein conserved in bacteria
LH23_RS16615	COG2731	YhcH YjgK YiaL family protein
LH23_RS16635	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS16645	COG1609	Transcriptional regulator
LH23_RS16650	COG0625	glutathione transferase activity
LH23_RS16655	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LH23_RS16670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LH23_RS16690	COG1942	4-Oxalocrotonate Tautomerase
LH23_RS16710	COG2246	polysaccharide biosynthetic process
LH23_RS16725	COG0814	amino acid
LH23_RS16740	COG0583	DNA-binding transcription factor activity
LH23_RS16805	COG0583	DNA-binding transcription factor activity
LH23_RS16825	COG2801	Transposase and inactivated derivatives
LH23_RS16830	COG2963	transposase activity
LH23_RS16845	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS16875	COG0251	oxidation-reduction process
LH23_RS16900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LH23_RS16910	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LH23_RS16920	COG2814	Major facilitator Superfamily
LH23_RS16930	COG0477	Major facilitator Superfamily
LH23_RS16940	COG2070	2-Nitropropane dioxygenase
LH23_RS16950	COG2249	NAD(P)H dehydrogenase (quinone) activity
LH23_RS16965	COG1649	PFAM Uncharacterised BCR, COG1649
LH23_RS16970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LH23_RS16975	COG0066	3-isopropylmalate dehydratase activity
LH23_RS16985	COG0583	DNA-binding transcription factor activity
LH23_RS16995	COG2134	cdp-diacylglycerol pyrophosphatase
LH23_RS17015	COG4221	oxidoreductase activity
LH23_RS17020	COG4221	oxidoreductase activity
LH23_RS17025	COG2207	Transcriptional regulator
LH23_RS17040	COG1335	isochorismatase
LH23_RS17085	COG1172	Belongs to the binding-protein-dependent transport system permease family
LH23_RS17100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LH23_RS17105	COG3829	transcription factor binding
LH23_RS17110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LH23_RS17115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LH23_RS17120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LH23_RS17130	COG0549	Belongs to the carbamate kinase family
LH23_RS17135	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LH23_RS17135	COG3608	succinylglutamate desuccinylase aspartoacylase
LH23_RS17140	COG2068	MobA-Related Protein
LH23_RS17145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LH23_RS17145	COG0493	'glutamate synthase
LH23_RS17150	COG0402	S-adenosylhomocysteine deaminase activity
LH23_RS17155	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LH23_RS17160	COG0493	'glutamate synthase
LH23_RS17160	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LH23_RS17165	COG2233	PERMEase
LH23_RS17170	COG3383	formate dehydrogenase (NAD+) activity
LH23_RS17175	COG3383	formate dehydrogenase (NAD+) activity
LH23_RS17215	COG2199	diguanylate cyclase activity
LH23_RS17225	COG2814	Major facilitator Superfamily
LH23_RS17235	COG0346	lactoylglutathione lyase activity
LH23_RS17245	COG0454	-acetyltransferase
LH23_RS17250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LH23_RS17265	COG3706	GGDEF domain
LH23_RS17275	COG2199	diguanylate cyclase activity
LH23_RS17280	COG2066	Belongs to the glutaminase family
LH23_RS17285	COG2203	Gaf domain
LH23_RS17285	COG0840	transmembrane signaling receptor activity
LH23_RS17290	COG1012	belongs to the aldehyde dehydrogenase family
LH23_RS17295	COG0583	DNA-binding transcription factor activity
LH23_RS17300	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS17315	COG2814	Major facilitator Superfamily
LH23_RS17325	COG1846	Transcriptional regulator
LH23_RS17330	COG4977	sequence-specific DNA binding
LH23_RS17340	COG0697	spore germination
LH23_RS17345	COG2814	Major facilitator Superfamily
LH23_RS17360	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LH23_RS17395	COG2084	Dehydrogenase
LH23_RS17405	COG0747	negative chemotaxis
LH23_RS17470	COG0488	(ABC) transporter
LH23_RS17485	COG0840	transmembrane signaling receptor activity
LH23_RS17490	COG3781	membrane
LH23_RS17495	COG0513	Belongs to the DEAD box helicase family
LH23_RS17515	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LH23_RS17540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LH23_RS17550	COG0235	Class ii aldolase
LH23_RS17560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LH23_RS17565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LH23_RS17570	COG1505	serine-type exopeptidase activity
LH23_RS17595	COG4251	negative regulation of phosphorylation
LH23_RS17595	COG5001	Diguanylate cyclase
LH23_RS17595	COG3706	GGDEF domain
LH23_RS17595	COG2203	Gaf domain
LH23_RS17600	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LH23_RS17605	COG4166	transmembrane transport
LH23_RS17610	COG2866	Carboxypeptidase
LH23_RS17615	COG4948	Mandelate Racemase Muconate Lactonizing
LH23_RS17620	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LH23_RS17650	COG3106	COG3106 Predicted ATPase
LH23_RS17660	COG1983	PspC domain protein
LH23_RS17670	COG1842	Phage shock protein A
LH23_RS17675	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LH23_RS17690	COG4171	peptide transport system, permease
LH23_RS17700	COG4172	Belongs to the ABC transporter superfamily
LH23_RS17710	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LH23_RS17710	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LH23_RS17720	COG5001	Diguanylate cyclase
LH23_RS17725	COG1024	Enoyl-CoA hydratase
LH23_RS17750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LH23_RS17755	COG1882	Formate acetyltransferase
LH23_RS17760	COG1349	DNA-binding transcription factor activity
LH23_RS17770	COG0023	Translation Initiation Factor
LH23_RS17775	COG0284	orotidine-5'-phosphate decarboxylase activity
LH23_RS17780	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LH23_RS17785	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LH23_RS17790	COG0671	phosphoesterase, PA-phosphatase related
LH23_RS17800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LH23_RS17820	COG0616	signal peptide processing
LH23_RS17825	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS17830	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LH23_RS17835	COG1187	pseudouridine synthase activity
LH23_RS17840	COG0789	Transcriptional regulator
LH23_RS17845	COG0009	L-threonylcarbamoyladenylate synthase
LH23_RS17850	COG0613	PHP domain protein
LH23_RS17855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LH23_RS17860	COG0512	Glutamine amidotransferase of anthranilate synthase
LH23_RS17860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LH23_RS17875	COG0159	tryptophan synthase activity
LH23_RS17885	COG3047	cAMP biosynthetic process
LH23_RS17895	COG2917	probably involved in intracellular septation
LH23_RS18010	COG2350	Protein conserved in bacteria
LH23_RS18015	COG2200	EAL domain
LH23_RS18020	COG3706	GGDEF domain
LH23_RS18040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LH23_RS18045	COG4608	Belongs to the ABC transporter superfamily
LH23_RS18050	COG0444	Belongs to the ABC transporter superfamily
LH23_RS18060	COG0601	transmembrane transport
LH23_RS18070	COG2095	MarC family integral membrane protein
LH23_RS18075	COG1454	alcohol dehydrogenase
LH23_RS18075	COG1012	belongs to the aldehyde dehydrogenase family
LH23_RS18085	COG2916	Histone family protein nucleoid-structuring protein H-NS
LH23_RS18095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LH23_RS18100	COG0745	RESPONSE REGULATOR receiver
LH23_RS18105	COG1752	Esterase of the alpha-beta hydrolase superfamily
LH23_RS18115	COG0788	formyltetrahydrofolate deformylase activity
LH23_RS18145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LH23_RS18150	COG0148	phosphopyruvate hydratase activity
LH23_RS18160	COG1227	inorganic diphosphatase activity
LH23_RS18170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LH23_RS18180	COG2181	nitrate reductase activity
LH23_RS18185	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LH23_RS18190	COG1140	nitrate reductase beta subunit
LH23_RS18195	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LH23_RS18200	COG2223	nitrite transmembrane transporter activity
LH23_RS18205	COG3850	Histidine kinase
LH23_RS18210	COG2197	response regulator
LH23_RS18215	COG4932	domain protein
LH23_RS18220	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LH23_RS18225	COG0840	transmembrane signaling receptor activity
LH23_RS18235	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LH23_RS18240	COG0387	Pfam Sodium calcium exchanger
LH23_RS18265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LH23_RS18290	COG0659	secondary active sulfate transmembrane transporter activity
LH23_RS18295	COG1942	4-Oxalocrotonate Tautomerase
LH23_RS18300	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS18305	COG0583	DNA-binding transcription factor activity
LH23_RS18325	COG0012	GTP binding
LH23_RS18330	COG0582	viral genome integration into host DNA
LH23_RS18335	COG2963	transposase activity
LH23_RS18340	COG2801	Transposase and inactivated derivatives
LH23_RS18365	COG2801	Transposase and inactivated derivatives
LH23_RS18370	COG2963	transposase activity
LH23_RS18410	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LH23_RS18445	COG2188	Transcriptional regulator
LH23_RS18455	COG1024	Enoyl-CoA hydratase
LH23_RS18460	COG1250	3-hydroxyacyl-CoA dehydrogenase
LH23_RS18470	COG2986	histidine ammonia-lyase
LH23_RS18515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LH23_RS18535	COG0477	Major facilitator Superfamily
LH23_RS18580	COG4774	siderophore transport
LH23_RS18600	COG1619	proteins homologs of microcin C7 resistance protein MccF
LH23_RS18620	COG2719	SpoVR family
LH23_RS18640	COG3042	response to heat
LH23_RS18655	COG0179	Fumarylacetoacetate (FAA) hydrolase
LH23_RS18660	COG2951	lytic endotransglycosylase activity
LH23_RS18670	COG0850	regulation of cytokinetic process
LH23_RS18675	COG2894	cell division
LH23_RS18690	COG0318	PFAM AMP-dependent synthetase and ligase
LH23_RS18695	COG3065	identical protein binding
LH23_RS18700	COG1214	PFAM Peptidase M22, glycoprotease
LH23_RS18705	COG1199	ATP-dependent helicase activity
LH23_RS18710	COG0251	oxidation-reduction process
LH23_RS18730	COG1760	l-serine dehydratase
LH23_RS18735	COG0583	DNA-binding transcription factor activity
LH23_RS18745	COG2200	EAL domain
LH23_RS18750	COG1253	flavin adenine dinucleotide binding
LH23_RS18755	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS18755	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LH23_RS18760	COG3715	PTS system
LH23_RS18765	COG3716	PTS system mannose fructose sorbose family IID component
LH23_RS18780	COG2226	methyltransferase
LH23_RS18785	COG0768	penicillin binding
LH23_RS18810	COG1414	Transcriptional regulator
LH23_RS18815	COG2814	Major facilitator Superfamily
LH23_RS18820	COG0501	Belongs to the peptidase M48B family
LH23_RS18825	COG0793	Belongs to the peptidase S41A family
LH23_RS18835	COG1956	GAF domain-containing protein
LH23_RS18840	COG2995	paraquat-inducible protein a
LH23_RS18845	COG3008	intermembrane lipid transfer
LH23_RS18875	COG0659	secondary active sulfate transmembrane transporter activity
LH23_RS18885	COG1276	copper resistance
LH23_RS18890	COG2372	response to copper ion
LH23_RS18900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LH23_RS18905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LH23_RS18910	COG1770	oligopeptidase
LH23_RS18915	COG2979	Protein of unknown function (DUF533)
LH23_RS18920	COG3141	response to X-ray
LH23_RS18930	COG0800	Aldolase
LH23_RS18935	COG0129	dihydroxy-acid dehydratase activity
LH23_RS18940	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LH23_RS18945	COG1737	Transcriptional regulator
LH23_RS18960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LH23_RS18965	COG1560	Kdo2-lipid A biosynthetic process
LH23_RS18970	COG0739	heme binding
LH23_RS18975	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LH23_RS18985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LH23_RS18995	COG0632	four-way junction helicase activity
LH23_RS19010	COG0494	nUDIX hydrolase
LH23_RS19015	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LH23_RS19020	COG1335	isochorismatase
LH23_RS19025	COG1801	Protein of unknown function DUF72
LH23_RS19030	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LH23_RS19050	COG3142	Participates in the control of copper homeostasis
LH23_RS19055	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LH23_RS19060	COG3102	Protein conserved in bacteria
LH23_RS19090	COG0745	RESPONSE REGULATOR receiver
LH23_RS19105	COG0840	transmembrane signaling receptor activity
LH23_RS19135	COG1301	dicarboxylic acid transport
LH23_RS19140	COG0835	chemotaxis
LH23_RS19175	COG1528	Iron-storage protein
LH23_RS19185	COG4608	Belongs to the ABC transporter superfamily
LH23_RS19190	COG0444	Belongs to the ABC transporter superfamily
LH23_RS19195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LH23_RS19200	COG0601	transmembrane transport
LH23_RS19210	COG0840	transmembrane signaling receptor activity
LH23_RS19230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LH23_RS19235	COG1528	Iron-storage protein
LH23_RS19240	COG3012	SEC-C Motif Domain Protein
LH23_RS19240	COG3318	Belongs to the UPF0149 family
LH23_RS19285	COG2197	response regulator
LH23_RS19295	COG2197	response regulator
LH23_RS19300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LH23_RS19305	COG1126	abc transporter atp-binding protein
LH23_RS19310	COG0765	amino acid transport
LH23_RS19320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LH23_RS19330	COG1191	sigma factor activity
LH23_RS19350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LH23_RS19380	COG0366	Alpha amylase catalytic
LH23_RS19390	COG2391	methyltransferase activity
LH23_RS19395	COG0425	Belongs to the sulfur carrier protein TusA family
LH23_RS19400	COG1737	Transcriptional regulator
LH23_RS19420	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LH23_RS19425	COG1317	bacterial-type flagellum organization
LH23_RS19430	COG1157	protein secretion by the type III secretion system
LH23_RS19435	COG2882	bacterial-type flagellum organization
LH23_RS19440	COG3144	bacterial-type flagellum assembly
LH23_RS19470	COG1987	bacterial-type flagellum assembly
LH23_RS19480	COG2197	response regulator
LH23_RS19505	COG5475	Uncharacterized small protein (DUF2158)
LH23_RS19510	COG2354	Protein conserved in bacteria
LH23_RS19515	COG0697	spore germination
LH23_RS19520	COG3727	T/G mismatch-specific endonuclease activity
LH23_RS19530	COG1418	mRNA catabolic process
LH23_RS19535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS19535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LH23_RS19535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS19535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS19535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LH23_RS19535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS19540	COG0383	alpha-mannosidase activity
LH23_RS19545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LH23_RS19545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LH23_RS19545	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LH23_RS19550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LH23_RS19580	COG1283	sodium-dependent phosphate transmembrane transporter activity
LH23_RS19590	COG1126	abc transporter atp-binding protein
LH23_RS19595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LH23_RS19600	COG0583	DNA-binding transcription factor activity
LH23_RS19605	COG2072	flavoprotein involved in K transport
LH23_RS19685	COG3210	domain, Protein
LH23_RS19725	COG3210	domain, Protein
LH23_RS19730	COG2831	hemolysin activation secretion protein
LH23_RS19750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LH23_RS19760	COG3272	Protein of unknown function (DUF1722)
LH23_RS19775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LH23_RS19790	COG0300	oxidoreductase activity
LH23_RS19800	COG0789	Transcriptional regulator
LH23_RS19810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LH23_RS19815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LH23_RS19820	COG1116	anion transmembrane transporter activity
LH23_RS19825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LH23_RS19830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LH23_RS19835	COG0523	cobalamin synthesis protein
LH23_RS19840	COG0840	transmembrane signaling receptor activity
LH23_RS19845	COG0583	DNA-binding transcription factor activity
LH23_RS19855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LH23_RS19860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LH23_RS19860	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LH23_RS19885	COG2771	luxR family
LH23_RS19890	COG0778	Nitroreductase
LH23_RS19905	COG0583	DNA-binding transcription factor activity
LH23_RS19910	COG0840	transmembrane signaling receptor activity
LH23_RS19915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LH23_RS19920	COG0006	proline dipeptidase activity
LH23_RS19935	COG0531	amino acid
LH23_RS19940	COG0174	glutamine synthetase
LH23_RS19945	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LH23_RS19950	COG1917	Cupin 2, conserved barrel domain protein
LH23_RS19950	COG1396	sequence-specific DNA binding
LH23_RS19955	COG1012	belongs to the aldehyde dehydrogenase family
LH23_RS19960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LH23_RS19970	COG1376	ErfK ybiS ycfS ynhG family protein
LH23_RS19975	COG0668	transmembrane transport
LH23_RS19980	COG0534	Mate efflux family protein
LH23_RS20005	COG4335	DNA alkylation repair
LH23_RS20020	COG0813	purine-nucleoside phosphorylase activity
LH23_RS20060	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LH23_RS20065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LH23_RS20070	COG0640	Transcriptional regulator
LH23_RS20080	COG1289	transmembrane transporter activity
LH23_RS20105	COG2925	Exonuclease
LH23_RS20110	COG0531	amino acid
LH23_RS20120	COG0583	DNA-binding transcription factor activity
LH23_RS20125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LH23_RS20130	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LH23_RS20135	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LH23_RS20150	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LH23_RS20170	COG1368	sulfuric ester hydrolase activity
LH23_RS20180	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LH23_RS20185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LH23_RS20230	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LH23_RS20240	COG0110	maltose O-acetyltransferase activity
LH23_RS20245	COG0110	maltose O-acetyltransferase activity
LH23_RS20265	COG2327	Polysaccharide pyruvyl transferase
LH23_RS20270	COG2244	polysaccharide biosynthetic process
LH23_RS20275	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LH23_RS20280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LH23_RS20290	COG0297	glycogen (starch) synthase activity
LH23_RS20295	COG1051	belongs to the nudix hydrolase family
LH23_RS20300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LH23_RS20305	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LH23_RS20310	COG0110	maltose O-acetyltransferase activity
LH23_RS20315	COG1216	Glycosyl transferase, family 2
LH23_RS20325	COG0438	transferase activity, transferring glycosyl groups
LH23_RS20330	COG1045	serine acetyltransferase
LH23_RS20335	COG0463	Glycosyl transferase, family 2
LH23_RS20340	COG3206	protein involved in exopolysaccharide biosynthesis
LH23_RS20340	COG0489	protein tyrosine kinase activity
LH23_RS20360	COG2982	Protein involved in outer membrane biogenesis
LH23_RS20375	COG5002	protein histidine kinase activity
LH23_RS20375	COG5001	Diguanylate cyclase
LH23_RS20375	COG3447	MASE1 domain protein
LH23_RS20380	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LH23_RS20385	COG0443	Heat shock 70 kDa protein
LH23_RS20420	COG2205	protein histidine kinase activity
LH23_RS20425	COG0745	RESPONSE REGULATOR receiver
LH23_RS20435	COG0826	peptidase U32
LH23_RS20450	COG1830	Aldolase
LH23_RS20460	COG2211	Major facilitator Superfamily
LH23_RS20465	COG1397	ADP-ribosylglycohydrolase
LH23_RS20470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LH23_RS20475	COG2188	Transcriptional regulator
LH23_RS20480	COG0351	phosphomethylpyrimidine kinase
LH23_RS20485	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LH23_RS20520	COG4772	TonB-dependent receptor
LH23_RS20525	COG2723	6-phospho-beta-galactosidase activity
LH23_RS20530	COG1263	PTS System
LH23_RS20530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LH23_RS20535	COG1609	Transcriptional regulator
LH23_RS20545	COG2814	Major facilitator Superfamily
LH23_RS20550	COG0667	Aldo Keto reductase
LH23_RS20555	COG0583	DNA-binding transcription factor activity
LH23_RS20560	COG0657	acetylesterase activity
LH23_RS20570	COG4807	Protein conserved in bacteria
LH23_RS20580	COG0625	glutathione transferase activity
LH23_RS20585	COG0489	protein tyrosine kinase activity
LH23_RS20595	COG2814	Major facilitator Superfamily
LH23_RS20600	COG0671	phosphoesterase, PA-phosphatase related
LH23_RS20605	COG1349	DNA-binding transcription factor activity
LH23_RS20610	COG1686	Belongs to the peptidase S11 family
LH23_RS20615	COG0625	glutathione transferase activity
LH23_RS20620	COG2133	pyrroloquinoline quinone binding
LH23_RS20635	COG3713	MltA-interacting MipA family protein
LH23_RS20670	COG0303	'Molybdopterin
LH23_RS20675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LH23_RS20680	COG2239	Acts as a magnesium transporter
LH23_RS20690	COG2271	Major facilitator Superfamily
LH23_RS20700	COG0488	(ABC) transporter
LH23_RS20705	COG1376	ErfK ybiS ycfS ynhG family protein
LH23_RS20715	COG1346	cytolysis
LH23_RS20720	COG0295	cytidine deaminase activity
LH23_RS20725	COG2949	membrane
LH23_RS20735	COG1129	ABC transporter
LH23_RS20750	COG2311	Membrane
LH23_RS20765	COG4771	TonB-dependent receptor
LH23_RS20775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LH23_RS20785	COG0833	amino acid
LH23_RS20790	COG1126	abc transporter atp-binding protein
LH23_RS20795	COG0765	amino acid transport
LH23_RS20810	COG0583	DNA-binding transcription factor activity
LH23_RS20815	COG2855	membrane
LH23_RS20825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LH23_RS20825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LH23_RS20825	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LH23_RS20830	COG1105	Belongs to the carbohydrate kinase PfkB family
LH23_RS20835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS20835	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS20845	COG4221	oxidoreductase activity
LH23_RS20850	COG0583	DNA-binding transcription factor activity
LH23_RS20855	COG2814	Major facilitator Superfamily
LH23_RS20880	COG0246	Mannitol dehydrogenase
LH23_RS20885	COG0523	cobalamin synthesis protein
LH23_RS20890	COG0671	phosphoesterase, PA-phosphatase related
LH23_RS20895	COG0791	NLP P60 protein
LH23_RS20900	COG2200	EAL domain
LH23_RS20905	COG4166	transmembrane transport
LH23_RS20910	COG4174	ABC transporter (Permease)
LH23_RS20915	COG4239	(ABC) transporter, permease
LH23_RS20920	COG4172	Belongs to the ABC transporter superfamily
LH23_RS20930	COG2814	Major facilitator Superfamily
LH23_RS20935	COG1187	pseudouridine synthase activity
LH23_RS20940	COG1061	Type III restriction enzyme res subunit
LH23_RS20955	COG3081	Nucleoid-associated protein
LH23_RS20960	COG3082	Protein of unknown function (DUF1414)
LH23_RS20980	COG2239	Acts as a magnesium transporter
LH23_RS20985	COG4615	Cyclic peptide transporter
LH23_RS20995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LH23_RS20995	COG2169	Transcriptional regulator
LH23_RS21010	COG2198	Histidine kinase
LH23_RS21010	COG0642	Histidine kinase
LH23_RS21015	COG2197	response regulator
LH23_RS21020	COG2205	protein histidine kinase activity
LH23_RS21020	COG0784	Response regulator, receiver
LH23_RS21035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LH23_RS21045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LH23_RS21050	COG0584	glycerophosphoryl diester phosphodiesterase
LH23_RS21055	COG2271	Major facilitator Superfamily
LH23_RS21060	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LH23_RS21065	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
LH23_RS21070	COG0247	lactate metabolic process
LH23_RS21115	COG1169	isochorismate synthase
LH23_RS21120	COG4575	ribosome binding
LH23_RS21125	COG2153	protein acetylation
LH23_RS21145	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LH23_RS21150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LH23_RS21155	COG0713	ATP synthesis coupled electron transport
LH23_RS21160	COG0839	Belongs to the complex I subunit 6 family
LH23_RS21195	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LH23_RS21205	COG0583	DNA-binding transcription factor activity
LH23_RS21210	COG0436	Aminotransferase
LH23_RS21220	COG0471	metal ion transport
LH23_RS21220	COG0490	domain, Protein
LH23_RS21225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LH23_RS21250	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LH23_RS21255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LH23_RS21260	COG3037	sugar-specific permease SgaT UlaA
LH23_RS21270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LH23_RS21275	COG1609	Transcriptional regulator
LH23_RS21285	COG0622	Phosphoesterase
LH23_RS21290	COG0625	glutathione transferase activity
LH23_RS21295	COG0625	glutathione transferase activity
LH23_RS21300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LH23_RS21305	COG1090	epimerase
LH23_RS21315	COG1070	Carbohydrate kinase
LH23_RS21320	COG0246	Mannitol dehydrogenase
LH23_RS21325	COG2390	Transcriptional regulator
LH23_RS21330	COG4598	ABC transporter
LH23_RS21335	COG4160	amino acid transport
LH23_RS21345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LH23_RS21355	COG0163	prenyltransferase activity
LH23_RS21360	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LH23_RS21365	COG1286	toxin biosynthetic process
LH23_RS21370	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LH23_RS21375	COG0285	dihydrofolate synthase activity
LH23_RS21385	COG0586	Pfam SNARE associated Golgi protein
LH23_RS21395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LH23_RS21415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LH23_RS21430	COG3101	peptidyl-lysine hydroxylation
LH23_RS21435	COG0730	response to heat
LH23_RS21450	COG2890	protein-(glutamine-N5) methyltransferase activity
LH23_RS21460	COG2062	phosphohistidine phosphatase, SixA
LH23_RS21475	COG3691	Protein conserved in bacteria
LH23_RS21485	COG2217	Heavy metal translocating P-type atpase
LH23_RS21510	COG4235	cytochrome complex assembly
LH23_RS21510	COG3088	subunit of a heme lyase
LH23_RS21515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LH23_RS21520	COG1138	Cytochrome C-type biogenesis protein
LH23_RS21530	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LH23_RS21535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LH23_RS21545	COG4133	protoheme IX ABC transporter activity
LH23_RS21550	COG2116	formate transmembrane transporter activity
LH23_RS21560	COG3122	Protein conserved in bacteria
LH23_RS21565	COG1051	belongs to the nudix hydrolase family
LH23_RS21575	COG1051	belongs to the nudix hydrolase family
LH23_RS21585	COG0456	acetyltransferase
LH23_RS21590	COG0583	DNA-binding transcription factor activity
LH23_RS21595	COG0583	DNA-binding transcription factor activity
LH23_RS21605	COG2207	Transcriptional regulator
LH23_RS21620	COG1566	PFAM secretion protein HlyD family protein
LH23_RS21630	COG0564	pseudouridine synthase activity
LH23_RS21645	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LH23_RS21655	COG1012	belongs to the aldehyde dehydrogenase family
LH23_RS21670	COG0531	amino acid
LH23_RS21675	COG4770	biotin carboxylase activity
LH23_RS21680	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LH23_RS21685	COG4336	lyase activity
LH23_RS21690	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LH23_RS21695	COG1914	H( )-stimulated, divalent metal cation uptake system
LH23_RS21720	COG0436	Aminotransferase
LH23_RS21730	COG3275	phosphorelay sensor kinase activity
LH23_RS21735	COG3279	Response regulator of the LytR AlgR family
LH23_RS21750	COG3961	Belongs to the TPP enzyme family
LH23_RS21755	COG0667	Aldo Keto reductase
LH23_RS21770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LH23_RS21780	COG2200	EAL domain
LH23_RS21780	COG2199	diguanylate cyclase activity
LH23_RS21795	COG3415	Transposase
LH23_RS21835	COG0583	DNA-binding transcription factor activity
LH23_RS21840	COG0385	Bile acid
LH23_RS21845	COG3530	Putative quorum-sensing-regulated virulence factor
LH23_RS21855	COG3115	cell septum assembly
LH23_RS21875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LH23_RS21895	COG2140	Oxalate decarboxylase
LH23_RS21900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LH23_RS21905	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LH23_RS21910	COG4208	sulfate ABC transporter
LH23_RS21915	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LH23_RS21920	COG4150	thiosulfate binding
LH23_RS21925	COG2837	iron assimilation
LH23_RS21945	COG0860	N-Acetylmuramoyl-L-alanine amidase
LH23_RS21965	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LH23_RS21970	COG5342	invasion associated locus B
LH23_RS21975	COG0494	nUDIX hydrolase
LH23_RS21980	COG3005	denitrification pathway
LH23_RS21985	COG3043	anaerobic respiration
LH23_RS21995	COG3062	negative regulation of establishment of protein localization
LH23_RS22000	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LH23_RS22000	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LH23_RS22005	COG3850	Histidine kinase
LH23_RS22010	COG2197	response regulator
LH23_RS22015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LH23_RS22020	COG1393	Belongs to the ArsC family
LH23_RS22035	COG0400	carboxylic ester hydrolase activity
LH23_RS22040	COG1444	tRNA N-acetyltransferase activity
LH23_RS22045	COG2321	neutral zinc metallopeptidase
LH23_RS22055	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LH23_RS22065	COG2716	regulation of RNA biosynthetic process
LH23_RS22070	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LH23_RS22080	COG1028	Short-chain dehydrogenase reductase Sdr
LH23_RS22090	COG0534	Mate efflux family protein
LH23_RS22095	COG0628	permease
LH23_RS22100	COG4783	chaperone-mediated protein folding
LH23_RS22105	COG1393	Belongs to the ArsC family
LH23_RS22130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LH23_RS22140	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LH23_RS22145	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LH23_RS22185	COG1464	Belongs to the NlpA lipoprotein family
LH23_RS22205	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LH23_RS22210	COG4181	ATPase activity
LH23_RS22215	COG2755	lipolytic protein G-D-S-L family
LH23_RS22220	COG0300	oxidoreductase activity
LH23_RS22225	COG3118	belongs to the thioredoxin family
LH23_RS22230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LH23_RS22235	COG0330	HflC and HflK could
LH23_RS22240	COG1585	Membrane protein implicated in regulation of membrane protease activity
LH23_RS22250	COG2217	Heavy metal translocating P-type atpase
LH23_RS22255	COG3735	TraB family
LH23_RS22260	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LH23_RS22265	COG0737	Belongs to the 5'-nucleotidase family
LH23_RS22270	COG2223	nitrite transmembrane transporter activity
LH23_RS22275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LH23_RS22275	COG4651	solute:proton antiporter activity
LH23_RS22280	COG3550	peptidyl-serine autophosphorylation
LH23_RS22285	COG1396	sequence-specific DNA binding
LH23_RS22290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LH23_RS22320	COG0583	DNA-binding transcription factor activity
LH23_RS22325	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LH23_RS22335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LH23_RS22340	COG2832	Protein of unknown function (DUF454)
LH23_RS22350	COG1196	nuclear chromosome segregation
LH23_RS22350	COG3264	Mechanosensitive ion channel
LH23_RS22355	COG1309	transcriptional regulator
LH23_RS22360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LH23_RS22365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LH23_RS22380	COG0110	maltose O-acetyltransferase activity
LH23_RS22390	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LH23_RS22400	COG0840	transmembrane signaling receptor activity
LH23_RS22410	COG1464	Belongs to the NlpA lipoprotein family
LH23_RS22420	COG2011	ABC-type metal ion transport system permease component
LH23_RS22425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LH23_RS22425	COG2190	(PTS) system
LH23_RS22425	COG1263	PTS System
LH23_RS22430	COG4948	Mandelate Racemase Muconate Lactonizing
LH23_RS22435	COG2188	Transcriptional regulator
LH23_RS22440	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LH23_RS22450	COG4149	molybdate abc transporter
LH23_RS22455	COG0725	ABC transporter, periplasmic molybdate-binding protein
LH23_RS22475	COG0371	Dehydrogenase
LH23_RS22485	COG1129	ABC transporter
LH23_RS22490	COG1172	Belongs to the binding-protein-dependent transport system permease family
LH23_RS22505	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LH23_RS22510	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LH23_RS22515	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LH23_RS22520	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
LH23_RS22525	COG0436	Aminotransferase
LH23_RS22535	COG2233	PERMEase
LH23_RS22545	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LH23_RS22550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LH23_RS22565	COG2200	EAL domain
LH23_RS22590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LH23_RS22600	COG1174	glycine betaine transport
LH23_RS22605	COG1174	glycine betaine transport
LH23_RS22615	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LH23_RS22620	COG1619	proteins homologs of microcin C7 resistance protein MccF
LH23_RS22635	COG1280	lysine exporter protein (LysE YggA)
LH23_RS22645	COG0006	proline dipeptidase activity
LH23_RS22650	COG1024	Enoyl-CoA hydratase
LH23_RS22650	COG1250	3-hydroxyacyl-CoA dehydrogenase
LH23_RS22655	COG1733	regulation of RNA biosynthetic process
LH23_RS22665	COG3423	Transcriptional regulator
LH23_RS22670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LH23_RS22670	COG0519	Catalyzes the synthesis of GMP from XMP
LH23_RS22675	COG0516	GMP reductase activity
LH23_RS22675	COG0517	IMP dehydrogenase activity
LH23_RS22680	COG1570	exodeoxyribonuclease VII activity
LH23_RS22685	COG1645	bacterial-type flagellum-dependent swarming motility
LH23_RS22690	COG0154	amidase activity
LH23_RS22695	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LH23_RS22700	COG1335	isochorismatase
LH23_RS22730	COG2976	Protein conserved in bacteria
LH23_RS22735	COG0124	histidyl-tRNA synthetase
LH23_RS22760	COG4953	penicillin-binding protein 1C
LH23_RS22765	COG2373	Large extracellular alpha-helical protein
LH23_RS22770	COG2897	thiosulfate sulfurtransferase activity
LH23_RS22785	COG2975	iron-sulfur cluster assembly
LH23_RS22790	COG0633	Ferredoxin
LH23_RS22810	COG0822	iron-sulfur transferase activity
LH23_RS22830	COG0483	inositol monophosphate 1-phosphatase activity
LH23_RS22835	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LH23_RS22840	COG3683	transport system, periplasmic component
LH23_RS22845	COG3711	transcriptional antiterminator
LH23_RS22850	COG2814	Major facilitator Superfamily
LH23_RS22860	COG0477	Major facilitator Superfamily
LH23_RS22860	COG2814	Major facilitator Superfamily
LH23_RS22865	COG0457	Tetratricopeptide repeat
LH23_RS22870	COG1940	carbohydrate kinase activity
LH23_RS22875	COG2259	Doxx family
LH23_RS22885	COG1129	ABC transporter
LH23_RS22890	COG1172	Belongs to the binding-protein-dependent transport system permease family
LH23_RS22905	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LH23_RS22905	COG0517	IMP dehydrogenase activity
LH23_RS22915	COG1017	nitric oxide dioxygenase activity
LH23_RS22915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LH23_RS22920	COG0347	Belongs to the P(II) protein family
LH23_RS22925	COG2204	response regulator
LH23_RS22930	COG3170	Tfp pilus assembly protein FimV
LH23_RS22935	COG2205	protein histidine kinase activity
LH23_RS22955	COG0560	Phosphoserine phosphatase
LH23_RS22960	COG1737	Transcriptional regulator
LH23_RS22965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LH23_RS23115	COG3710	Transcriptional regulator