locus-tag	class	description
IMCC12053_RS00030	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IMCC12053_RS00030	COG0662	Cupin 2, conserved barrel domain protein
IMCC12053_RS00035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC12053_RS00045	COG0463	Glycosyl transferase, family 2
IMCC12053_RS00115	COG1475	DNA binding
IMCC12053_RS00170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC12053_RS00175	COG4191	Histidine kinase
IMCC12053_RS00175	COG0784	Response regulator, receiver
IMCC12053_RS00185	COG1840	ABC-type Fe3 transport system, periplasmic component
IMCC12053_RS00200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMCC12053_RS00205	COG4974	Belongs to the 'phage' integrase family
IMCC12053_RS00210	COG0517	IMP dehydrogenase activity
IMCC12053_RS00230	COG2932	Transcriptional regulator
IMCC12053_RS00270	COG1061	Type III restriction enzyme res subunit
IMCC12053_RS00360	COG0740	serine-type endopeptidase activity
IMCC12053_RS00385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMCC12053_RS00440	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IMCC12053_RS00455	COG4786	Flagellar basal body rod
IMCC12053_RS00480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IMCC12053_RS00490	COG0038	chloride channel
IMCC12053_RS00495	COG4786	Flagellar basal body rod
IMCC12053_RS00520	COG1677	Flagellar hook-basal body complex protein FliE
IMCC12053_RS00530	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IMCC12053_RS00580	COG1987	bacterial-type flagellum assembly
IMCC12053_RS00620	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IMCC12053_RS00625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IMCC12053_RS00625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IMCC12053_RS00645	COG2801	Transposase and inactivated derivatives
IMCC12053_RS00650	COG2963	transposase activity
IMCC12053_RS00675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMCC12053_RS00695	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IMCC12053_RS00755	COG2894	cell division
IMCC12053_RS00815	COG2308	Evidence 4 Homologs of previously reported genes of
IMCC12053_RS00835	COG1116	anion transmembrane transporter activity
IMCC12053_RS00855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IMCC12053_RS00860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMCC12053_RS00865	COG1116	anion transmembrane transporter activity
IMCC12053_RS00865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IMCC12053_RS00870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMCC12053_RS00875	COG2146	nitrite reductase [NAD(P)H] activity
IMCC12053_RS00880	COG0243	molybdopterin cofactor binding
IMCC12053_RS00905	COG5642	Protein of unknown function (DUF2384)
IMCC12053_RS00925	COG0500	methyltransferase
IMCC12053_RS00935	COG0673	inositol 2-dehydrogenase activity
IMCC12053_RS00945	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS00955	COG0673	inositol 2-dehydrogenase activity
IMCC12053_RS00960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC12053_RS00965	COG3962	Belongs to the TPP enzyme family
IMCC12053_RS00970	COG1082	Xylose isomerase domain protein TIM barrel
IMCC12053_RS00975	COG3718	enzyme involved in inositol metabolism
IMCC12053_RS00980	COG3622	Belongs to the hyi family
IMCC12053_RS01030	COG0156	8-amino-7-oxononanoate synthase activity
IMCC12053_RS01040	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IMCC12053_RS01050	COG0436	Aminotransferase
IMCC12053_RS01055	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMCC12053_RS01060	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IMCC12053_RS01065	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IMCC12053_RS01110	COG0673	inositol 2-dehydrogenase activity
IMCC12053_RS01120	COG1609	Transcriptional regulator
IMCC12053_RS01125	COG1653	transport
IMCC12053_RS01130	COG1175	transmembrane transport
IMCC12053_RS01135	COG0395	ABC-type sugar transport system, permease component
IMCC12053_RS01140	COG3842	ATPase activity
IMCC12053_RS01145	COG3250	beta-galactosidase activity
IMCC12053_RS01165	COG0667	Aldo Keto reductase
IMCC12053_RS01170	COG3507	Belongs to the glycosyl hydrolase 43 family
IMCC12053_RS01175	COG0823	Involved in the tonB-independent uptake of proteins
IMCC12053_RS01190	COG1940	carbohydrate kinase activity
IMCC12053_RS01195	COG4213	ABC transporter substrate-binding protein
IMCC12053_RS01200	COG4214	carbohydrate transport
IMCC12053_RS01205	COG1129	ABC transporter
IMCC12053_RS01210	COG1070	Carbohydrate kinase
IMCC12053_RS01215	COG2115	Belongs to the xylose isomerase family
IMCC12053_RS01220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC12053_RS01225	COG1802	Transcriptional regulator
IMCC12053_RS01230	COG1904	glucuronate isomerase
IMCC12053_RS01235	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IMCC12053_RS01240	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC12053_RS01245	COG0246	Mannitol dehydrogenase
IMCC12053_RS01250	COG1648	precorrin-2 dehydrogenase activity
IMCC12053_RS01250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IMCC12053_RS01255	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IMCC12053_RS01265	COG0028	Belongs to the TPP enzyme family
IMCC12053_RS01270	COG1012	belongs to the aldehyde dehydrogenase family
IMCC12053_RS01285	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMCC12053_RS01290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IMCC12053_RS01315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMCC12053_RS01350	COG2081	HI0933 family
IMCC12053_RS01365	COG0316	Belongs to the HesB IscA family
IMCC12053_RS01370	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IMCC12053_RS01375	COG0667	Aldo Keto reductase
IMCC12053_RS01385	COG0018	arginyl-trna synthetase
IMCC12053_RS01400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMCC12053_RS01405	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMCC12053_RS01415	COG0717	Belongs to the dCTP deaminase family
IMCC12053_RS01430	COG0776	regulation of translation
IMCC12053_RS01435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMCC12053_RS01440	COG0416	fatty acid biosynthetic process
IMCC12053_RS01455	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMCC12053_RS01465	COG0488	(ABC) transporter
IMCC12053_RS01475	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMCC12053_RS01480	COG2890	protein-(glutamine-N5) methyltransferase activity
IMCC12053_RS01490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IMCC12053_RS01495	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IMCC12053_RS01500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMCC12053_RS01520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMCC12053_RS01530	COG3577	Aspartyl protease
IMCC12053_RS01535	COG2095	MarC family integral membrane protein
IMCC12053_RS01540	COG0488	(ABC) transporter
IMCC12053_RS01545	COG0105	UTP biosynthetic process
IMCC12053_RS01555	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IMCC12053_RS01565	COG4175	Glycine betaine
IMCC12053_RS01595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IMCC12053_RS01605	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC12053_RS01615	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC12053_RS01635	COG1309	transcriptional regulator
IMCC12053_RS01645	COG2313	pseudouridylate synthase activity
IMCC12053_RS01655	COG0052	Belongs to the universal ribosomal protein uS2 family
IMCC12053_RS01660	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMCC12053_RS01665	COG2197	response regulator
IMCC12053_RS01680	COG4235	cytochrome complex assembly
IMCC12053_RS01685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMCC12053_RS01695	COG0730	response to heat
IMCC12053_RS01700	COG2814	Major facilitator Superfamily
IMCC12053_RS01705	COG0604	alcohol dehydrogenase
IMCC12053_RS01710	COG2188	Transcriptional regulator
IMCC12053_RS01725	COG0114	fumarate hydratase activity
IMCC12053_RS01745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC12053_RS01750	COG0215	cysteine-tRNA ligase activity
IMCC12053_RS01755	COG3956	TIGRFAM MazG family protein
IMCC12053_RS01760	COG1840	ABC-type Fe3 transport system, periplasmic component
IMCC12053_RS01770	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IMCC12053_RS01775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IMCC12053_RS01780	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IMCC12053_RS01795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC12053_RS01835	COG0587	DNA-directed DNA polymerase activity
IMCC12053_RS01875	COG0673	inositol 2-dehydrogenase activity
IMCC12053_RS01880	COG1414	Transcriptional regulator
IMCC12053_RS01885	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IMCC12053_RS01895	COG0154	amidase activity
IMCC12053_RS01910	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IMCC12053_RS01920	COG0625	glutathione transferase activity
IMCC12053_RS01935	COG4988	ABC transporter
IMCC12053_RS01940	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IMCC12053_RS01950	COG1294	oxidase, subunit
IMCC12053_RS01985	COG1129	ABC transporter
IMCC12053_RS01990	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS02005	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC12053_RS02010	COG4166	transmembrane transport
IMCC12053_RS02030	COG2814	Major facilitator Superfamily
IMCC12053_RS02035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IMCC12053_RS02055	COG0248	Ppx GppA phosphatase
IMCC12053_RS02065	COG1410	methionine synthase
IMCC12053_RS02065	COG0646	methionine synthase
IMCC12053_RS02100	COG2801	Transposase and inactivated derivatives
IMCC12053_RS02105	COG0582	viral genome integration into host DNA
IMCC12053_RS02115	COG0166	Belongs to the GPI family
IMCC12053_RS02125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IMCC12053_RS02160	COG1797	cobyrinic acid a,c-diamide synthase activity
IMCC12053_RS02165	COG2814	Major facilitator Superfamily
IMCC12053_RS02170	COG0494	nUDIX hydrolase
IMCC12053_RS02180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IMCC12053_RS02185	COG0415	Belongs to the DNA photolyase family
IMCC12053_RS02190	COG5265	(ABC) transporter
IMCC12053_RS02205	COG2962	Rard protein
IMCC12053_RS02215	COG0673	inositol 2-dehydrogenase activity
IMCC12053_RS02220	COG0745	RESPONSE REGULATOR receiver
IMCC12053_RS02230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMCC12053_RS02240	COG0573	inorganic phosphate transmembrane transporter activity
IMCC12053_RS02250	COG5002	protein histidine kinase activity
IMCC12053_RS02260	COG0194	GDP metabolic process
IMCC12053_RS02275	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IMCC12053_RS02330	COG2321	neutral zinc metallopeptidase
IMCC12053_RS02335	COG1238	metal cluster binding
IMCC12053_RS02345	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMCC12053_RS02350	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IMCC12053_RS02355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMCC12053_RS02360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IMCC12053_RS02375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IMCC12053_RS02380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMCC12053_RS02395	COG0482	sulfurtransferase activity
IMCC12053_RS02410	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IMCC12053_RS02420	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IMCC12053_RS02425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IMCC12053_RS02435	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IMCC12053_RS02440	COG0750	zinc metalloprotease
IMCC12053_RS02445	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IMCC12053_RS02450	COG0575	Belongs to the CDS family
IMCC12053_RS02455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMCC12053_RS02460	COG0233	cytoplasmic translational termination
IMCC12053_RS02470	COG0528	UMP kinase activity
IMCC12053_RS02475	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMCC12053_RS02485	COG0739	heme binding
IMCC12053_RS02485	COG0741	lytic transglycosylase activity
IMCC12053_RS02485	COG1196	nuclear chromosome segregation
IMCC12053_RS02490	COG0629	single-stranded DNA binding
IMCC12053_RS02495	COG0840	transmembrane signaling receptor activity
IMCC12053_RS02500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IMCC12053_RS02505	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IMCC12053_RS02520	COG4974	Belongs to the 'phage' integrase family
IMCC12053_RS02525	COG4536	flavin adenine dinucleotide binding
IMCC12053_RS02530	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IMCC12053_RS02535	COG0433	COG0433 Predicted ATPase
IMCC12053_RS02560	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IMCC12053_RS02575	COG3108	Peptidase M15
IMCC12053_RS02610	COG0719	Fe-S assembly protein
IMCC12053_RS02615	COG0396	ATPase activity
IMCC12053_RS02635	COG0393	Putative heavy-metal-binding
IMCC12053_RS02645	COG0719	Fe-S assembly protein
IMCC12053_RS02650	COG1104	cysteine desulfurase activity
IMCC12053_RS02655	COG1959	2 iron, 2 sulfur cluster binding
IMCC12053_RS02660	COG2945	thiolester hydrolase activity
IMCC12053_RS02680	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IMCC12053_RS02685	COG1612	heme a metabolic process
IMCC12053_RS02690	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IMCC12053_RS02720	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMCC12053_RS02725	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMCC12053_RS02730	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMCC12053_RS02740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IMCC12053_RS02745	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IMCC12053_RS02745	COG3743	rRNA binding
IMCC12053_RS02760	COG1294	oxidase, subunit
IMCC12053_RS02765	COG1271	oxidase subunit
IMCC12053_RS02785	COG1959	2 iron, 2 sulfur cluster binding
IMCC12053_RS02795	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IMCC12053_RS02800	COG2084	Dehydrogenase
IMCC12053_RS02820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMCC12053_RS02825	COG1923	regulation of RNA biosynthetic process
IMCC12053_RS02830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMCC12053_RS02835	COG0569	domain protein
IMCC12053_RS02840	COG2204	response regulator
IMCC12053_RS02845	COG5000	phosphorelay sensor kinase activity
IMCC12053_RS02850	COG2204	response regulator
IMCC12053_RS02855	COG3852	Histidine kinase
IMCC12053_RS02860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMCC12053_RS02865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IMCC12053_RS02865	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IMCC12053_RS02870	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IMCC12053_RS02875	COG1546	Belongs to the CinA family
IMCC12053_RS02875	COG1058	Belongs to the CinA family
IMCC12053_RS02880	COG0004	ammonium transporteR
IMCC12053_RS02885	COG2867	negative regulation of translational initiation
IMCC12053_RS02890	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IMCC12053_RS02925	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMCC12053_RS02925	COG0519	Catalyzes the synthesis of GMP from XMP
IMCC12053_RS02935	COG0697	spore germination
IMCC12053_RS02955	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IMCC12053_RS02960	COG0596	Alpha beta hydrolase
IMCC12053_RS02965	COG2326	polyphosphate kinase activity
IMCC12053_RS02970	COG1309	transcriptional regulator
IMCC12053_RS03020	COG2894	cell division
IMCC12053_RS03040	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMCC12053_RS03050	COG0538	isocitrate dehydrogenase activity
IMCC12053_RS03075	COG1217	gtp-binding protein TYPA
IMCC12053_RS03080	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC12053_RS03095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMCC12053_RS03100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMCC12053_RS03115	COG0517	IMP dehydrogenase activity
IMCC12053_RS03115	COG0516	GMP reductase activity
IMCC12053_RS03125	COG3842	ATPase activity
IMCC12053_RS03130	COG0366	Alpha amylase catalytic
IMCC12053_RS03135	COG0395	ABC-type sugar transport system, permease component
IMCC12053_RS03140	COG1175	transmembrane transport
IMCC12053_RS03145	COG1653	transport
IMCC12053_RS03150	COG1609	Transcriptional regulator
IMCC12053_RS03155	COG2723	6-phospho-beta-galactosidase activity
IMCC12053_RS03160	COG0837	glucose binding
IMCC12053_RS03170	COG0745	RESPONSE REGULATOR receiver
IMCC12053_RS03180	COG0835	chemotaxis
IMCC12053_RS03185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IMCC12053_RS03190	COG0745	RESPONSE REGULATOR receiver
IMCC12053_RS03205	COG2201	protein-glutamate methylesterase activity
IMCC12053_RS03210	COG0840	transmembrane signaling receptor activity
IMCC12053_RS03245	COG0544	peptidyl-prolyl cis-trans isomerase activity
IMCC12053_RS03255	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IMCC12053_RS03255	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IMCC12053_RS03285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMCC12053_RS03290	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IMCC12053_RS03315	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMCC12053_RS03330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMCC12053_RS03340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMCC12053_RS03345	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMCC12053_RS03350	COG4133	protoheme IX ABC transporter activity
IMCC12053_RS03355	COG3737	Protein of unknown function (DUF498/DUF598)
IMCC12053_RS03360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMCC12053_RS03365	COG1862	Preprotein translocase
IMCC12053_RS03370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IMCC12053_RS03375	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IMCC12053_RS03390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMCC12053_RS03405	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IMCC12053_RS03415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IMCC12053_RS03420	COG2833	Protein of unknown function (DUF455)
IMCC12053_RS03425	COG0739	heme binding
IMCC12053_RS03435	COG0697	spore germination
IMCC12053_RS03455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMCC12053_RS03460	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC12053_RS03465	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IMCC12053_RS03470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC12053_RS03490	COG2124	cytochrome p450
IMCC12053_RS03495	COG0134	indole-3-glycerol-phosphate synthase activity
IMCC12053_RS03500	COG0315	cyclic pyranopterin monophosphate synthase activity
IMCC12053_RS03505	COG0303	'Molybdopterin
IMCC12053_RS03510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IMCC12053_RS03515	COG0658	competence protein
IMCC12053_RS03515	COG2333	competence protein COMEC
IMCC12053_RS03520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMCC12053_RS03525	COG0372	Belongs to the citrate synthase family
IMCC12053_RS03535	COG1024	Enoyl-CoA hydratase
IMCC12053_RS03540	COG3088	subunit of a heme lyase
IMCC12053_RS03545	COG1138	Cytochrome C-type biogenesis protein
IMCC12053_RS03570	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IMCC12053_RS03575	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IMCC12053_RS03580	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IMCC12053_RS03590	COG0583	DNA-binding transcription factor activity
IMCC12053_RS03595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMCC12053_RS03610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IMCC12053_RS03625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IMCC12053_RS03650	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMCC12053_RS03655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IMCC12053_RS03655	COG0617	tRNA 3'-terminal CCA addition
IMCC12053_RS03655	COG0517	IMP dehydrogenase activity
IMCC12053_RS03685	COG0737	Belongs to the 5'-nucleotidase family
IMCC12053_RS03690	COG3258	Cytochrome c
IMCC12053_RS03715	COG0785	Cytochrome C biogenesis protein
IMCC12053_RS03735	COG2391	methyltransferase activity
IMCC12053_RS03740	COG2379	hydroxypyruvate reductase
IMCC12053_RS03745	COG0259	pyridoxamine-phosphate oxidase activity
IMCC12053_RS03750	COG0709	Synthesizes selenophosphate from selenide and ATP
IMCC12053_RS03755	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
IMCC12053_RS03775	COG0321	lipoyl(octanoyl) transferase activity
IMCC12053_RS03780	COG3474	cytochrome
IMCC12053_RS03805	COG1610	YqeY-like protein
IMCC12053_RS03810	COG0505	Belongs to the CarA family
IMCC12053_RS03820	COG1802	Transcriptional regulator
IMCC12053_RS03850	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMCC12053_RS03865	COG0484	heat shock protein binding
IMCC12053_RS03870	COG2354	Protein conserved in bacteria
IMCC12053_RS03875	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IMCC12053_RS03890	COG0006	proline dipeptidase activity
IMCC12053_RS03905	COG0277	FAD linked oxidase domain protein
IMCC12053_RS03915	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IMCC12053_RS03920	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IMCC12053_RS03925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMCC12053_RS03930	COG0849	cell division
IMCC12053_RS03935	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IMCC12053_RS03940	COG1181	Belongs to the D-alanine--D-alanine ligase family
IMCC12053_RS03945	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IMCC12053_RS03955	COG0531	amino acid
IMCC12053_RS03970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IMCC12053_RS03975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMCC12053_RS03990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC12053_RS04000	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMCC12053_RS04005	COG0768	penicillin binding
IMCC12053_RS04015	COG0275	rRNA processing
IMCC12053_RS04020	COG2001	Belongs to the MraZ family
IMCC12053_RS04025	COG0489	protein tyrosine kinase activity
IMCC12053_RS04035	COG2801	Transposase and inactivated derivatives
IMCC12053_RS04045	COG0210	DNA helicase
IMCC12053_RS04055	COG0477	Major facilitator Superfamily
IMCC12053_RS04060	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IMCC12053_RS04085	COG0131	Imidazoleglycerol-phosphate dehydratase
IMCC12053_RS04090	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IMCC12053_RS04100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IMCC12053_RS04110	COG0107	imidazoleglycerol-phosphate synthase activity
IMCC12053_RS04115	COG0140	phosphoribosyl-ATP diphosphatase activity
IMCC12053_RS04125	COG1832	CoA-binding protein
IMCC12053_RS04130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMCC12053_RS04165	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IMCC12053_RS04170	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IMCC12053_RS04175	COG1329	Transcriptional regulator
IMCC12053_RS04180	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IMCC12053_RS04185	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IMCC12053_RS04195	COG0457	Tetratricopeptide repeat
IMCC12053_RS04230	COG0564	pseudouridine synthase activity
IMCC12053_RS04255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMCC12053_RS04260	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IMCC12053_RS04290	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IMCC12053_RS04290	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IMCC12053_RS04300	COG0432	Pfam Uncharacterised protein family UPF0047
IMCC12053_RS04315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMCC12053_RS04320	COG0358	DNA primase activity
IMCC12053_RS04365	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IMCC12053_RS04400	COG0546	phosphoglycolate phosphatase activity
IMCC12053_RS04440	COG2326	polyphosphate kinase activity
IMCC12053_RS04450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMCC12053_RS04455	COG3002	Belongs to the UPF0753 family
IMCC12053_RS04460	COG0187	DNA topoisomerase II activity
IMCC12053_RS04475	COG1136	(ABC) transporter
IMCC12053_RS04495	COG0442	prolyl-tRNA aminoacylation
IMCC12053_RS04505	COG0840	transmembrane signaling receptor activity
IMCC12053_RS04510	COG0628	permease
IMCC12053_RS04520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IMCC12053_RS04525	COG0248	Ppx GppA phosphatase
IMCC12053_RS04530	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IMCC12053_RS04545	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMCC12053_RS04545	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMCC12053_RS04555	COG4770	biotin carboxylase activity
IMCC12053_RS04570	COG0251	oxidation-reduction process
IMCC12053_RS04585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IMCC12053_RS04590	COG2814	Major facilitator Superfamily
IMCC12053_RS04595	COG1396	sequence-specific DNA binding
IMCC12053_RS04595	COG3800	Transcriptional regulator
IMCC12053_RS04610	COG1136	(ABC) transporter
IMCC12053_RS04610	COG0577	efflux transmembrane transporter activity
IMCC12053_RS04615	COG0577	efflux transmembrane transporter activity
IMCC12053_RS04615	COG1136	(ABC) transporter
IMCC12053_RS04655	COG0217	transcriptional regulatory protein
IMCC12053_RS04660	COG0471	metal ion transport
IMCC12053_RS04660	COG3273	potassium ion transport
IMCC12053_RS04665	COG1692	metallophosphoesterase
IMCC12053_RS04675	COG2239	Acts as a magnesium transporter
IMCC12053_RS04680	COG0402	S-adenosylhomocysteine deaminase activity
IMCC12053_RS04705	COG0583	DNA-binding transcription factor activity
IMCC12053_RS04715	COG0670	Belongs to the BI1 family
IMCC12053_RS04725	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IMCC12053_RS04740	COG3023	N-Acetylmuramoyl-L-alanine amidase
IMCC12053_RS04750	COG0154	amidase activity
IMCC12053_RS04755	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMCC12053_RS04770	COG0590	tRNA wobble adenosine to inosine editing
IMCC12053_RS04775	COG1187	pseudouridine synthase activity
IMCC12053_RS04785	COG3853	Toxic anion resistance protein (TelA)
IMCC12053_RS04820	COG1490	D-aminoacyl-tRNA deacylase activity
IMCC12053_RS04825	COG3806	Anti-sigma factor
IMCC12053_RS04830	COG1595	DNA-templated transcription, initiation
IMCC12053_RS04855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMCC12053_RS04865	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMCC12053_RS04880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IMCC12053_RS04890	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IMCC12053_RS04895	COG4149	molybdate abc transporter
IMCC12053_RS04900	COG0725	ABC transporter, periplasmic molybdate-binding protein
IMCC12053_RS04910	COG0287	Prephenate dehydrogenase
IMCC12053_RS04920	COG1850	ribulose-bisphosphate carboxylase activity
IMCC12053_RS04930	COG0010	Belongs to the arginase family
IMCC12053_RS04960	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IMCC12053_RS04965	COG0489	protein tyrosine kinase activity
IMCC12053_RS04975	COG1091	dTDP-4-dehydrorhamnose reductase activity
IMCC12053_RS04985	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IMCC12053_RS04990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMCC12053_RS04995	COG0395	ABC-type sugar transport system, permease component
IMCC12053_RS05005	COG1349	DNA-binding transcription factor activity
IMCC12053_RS05015	COG3842	ATPase activity
IMCC12053_RS05020	COG3842	ATPase activity
IMCC12053_RS05030	COG0395	ABC-type sugar transport system, permease component
IMCC12053_RS05045	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMCC12053_RS05050	COG0754	glutathionylspermidine amidase activity
IMCC12053_RS05065	COG0596	Alpha beta hydrolase
IMCC12053_RS05085	COG0481	GTPase activity
IMCC12053_RS05100	COG3128	pkhd-type hydroxylase
IMCC12053_RS05115	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IMCC12053_RS05120	COG1703	isobutyryl-CoA mutase activity
IMCC12053_RS05125	COG1643	Atp-dependent helicase
IMCC12053_RS05130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IMCC12053_RS05140	COG0306	phosphate transporter
IMCC12053_RS05150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IMCC12053_RS05160	COG0842	Transport permease protein
IMCC12053_RS05170	COG1131	(ABC) transporter
IMCC12053_RS05175	COG0842	Transport permease protein
IMCC12053_RS05180	COG2353	YceI-like domain
IMCC12053_RS05190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMCC12053_RS05205	COG1054	Belongs to the UPF0176 family
IMCC12053_RS05240	COG0778	Nitroreductase
IMCC12053_RS05255	COG0346	lactoylglutathione lyase activity
IMCC12053_RS05260	COG0745	RESPONSE REGULATOR receiver
IMCC12053_RS05265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IMCC12053_RS05275	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IMCC12053_RS05280	COG0513	Belongs to the DEAD box helicase family
IMCC12053_RS05285	COG1435	thymidine kinase activity
IMCC12053_RS05290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMCC12053_RS05295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMCC12053_RS05310	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMCC12053_RS05320	COG1496	oxidoreductase activity
IMCC12053_RS05330	COG1522	sequence-specific DNA binding
IMCC12053_RS05335	COG0492	ferredoxin-NADP+ reductase activity
IMCC12053_RS05340	COG0529	Catalyzes the synthesis of activated sulfate
IMCC12053_RS05340	COG2046	Belongs to the sulfate adenylyltransferase family
IMCC12053_RS05365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IMCC12053_RS05370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IMCC12053_RS05375	COG0494	nUDIX hydrolase
IMCC12053_RS05385	COG0459	protein refolding
IMCC12053_RS05400	COG1227	inorganic diphosphatase activity
IMCC12053_RS05405	COG1247	-acetyltransferase
IMCC12053_RS05415	COG2030	dehydratase
IMCC12053_RS05420	COG0196	riboflavin kinase activity
IMCC12053_RS05425	COG2983	Belongs to the UPF0260 family
IMCC12053_RS05455	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IMCC12053_RS05460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IMCC12053_RS05465	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IMCC12053_RS05470	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMCC12053_RS05480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMCC12053_RS05505	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IMCC12053_RS05515	COG0287	Prephenate dehydrogenase
IMCC12053_RS05520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IMCC12053_RS05525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMCC12053_RS05575	COG1012	belongs to the aldehyde dehydrogenase family
IMCC12053_RS05595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMCC12053_RS05605	COG0247	lactate metabolic process
IMCC12053_RS05610	COG0277	FAD linked oxidase domain protein
IMCC12053_RS05615	COG0277	FAD linked oxidase domain protein
IMCC12053_RS05640	COG0714	Associated with various cellular activities
IMCC12053_RS05675	COG1131	(ABC) transporter
IMCC12053_RS05685	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMCC12053_RS05685	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMCC12053_RS05690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC12053_RS05695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IMCC12053_RS05705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMCC12053_RS05710	COG2885	chlorophyll binding
IMCC12053_RS05720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMCC12053_RS05725	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMCC12053_RS05735	COG0356	it plays a direct role in the translocation of protons across the membrane
IMCC12053_RS05765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMCC12053_RS05780	COG0228	four-way junction DNA binding
IMCC12053_RS05785	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IMCC12053_RS05795	COG0336	Belongs to the RNA methyltransferase TrmD family
IMCC12053_RS05800	COG0335	large ribosomal subunit rRNA binding
IMCC12053_RS05805	COG0254	rRNA binding
IMCC12053_RS05815	COG2151	metal-sulfur cluster biosynthetic enzyme
IMCC12053_RS05815	COG0489	protein tyrosine kinase activity
IMCC12053_RS05830	COG1618	nucleotide phosphatase activity, acting on free nucleotides
IMCC12053_RS05830	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IMCC12053_RS05840	COG0425	Belongs to the sulfur carrier protein TusA family
IMCC12053_RS05850	COG2197	response regulator
IMCC12053_RS05870	COG2197	response regulator
IMCC12053_RS05890	COG0129	dihydroxy-acid dehydratase activity
IMCC12053_RS05900	COG4214	carbohydrate transport
IMCC12053_RS05910	COG4213	ABC transporter substrate-binding protein
IMCC12053_RS05925	COG0411	ABC transporter
IMCC12053_RS05935	COG0559	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS05955	COG4181	ATPase activity
IMCC12053_RS05980	COG0348	domain, Protein
IMCC12053_RS05985	COG2010	Cytochrome c
IMCC12053_RS06010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMCC12053_RS06015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IMCC12053_RS06020	COG0277	FAD linked oxidase domain protein
IMCC12053_RS06030	COG0181	hydroxymethylbilane synthase activity
IMCC12053_RS06035	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IMCC12053_RS06045	COG0408	coproporphyrinogen oxidase activity
IMCC12053_RS06060	COG2813	Specifically methylates the guanine in position
IMCC12053_RS06065	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IMCC12053_RS06075	COG1686	Belongs to the peptidase S11 family
IMCC12053_RS06080	COG4172	Belongs to the ABC transporter superfamily
IMCC12053_RS06085	COG4239	(ABC) transporter, permease
IMCC12053_RS06090	COG4174	ABC transporter (Permease)
IMCC12053_RS06095	COG4166	transmembrane transport
IMCC12053_RS06105	COG1605	Chorismate mutase
IMCC12053_RS06105	COG0077	Prephenate dehydratase
IMCC12053_RS06115	COG2816	NAD+ diphosphatase activity
IMCC12053_RS06120	COG0737	Belongs to the 5'-nucleotidase family
IMCC12053_RS06130	COG1162	GTPase activity
IMCC12053_RS06145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMCC12053_RS06170	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IMCC12053_RS06185	COG1012	belongs to the aldehyde dehydrogenase family
IMCC12053_RS06195	COG1522	sequence-specific DNA binding
IMCC12053_RS06200	COG1970	mechanosensitive ion channel activity
IMCC12053_RS06205	COG0625	glutathione transferase activity
IMCC12053_RS06215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMCC12053_RS06215	COG0072	phenylalanine-tRNA ligase activity
IMCC12053_RS06230	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMCC12053_RS06235	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMCC12053_RS06240	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IMCC12053_RS06250	COG0469	pyruvate kinase activity
IMCC12053_RS06275	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC12053_RS06285	COG2301	Belongs to the HpcH HpaI aldolase family
IMCC12053_RS06290	COG0825	malonyl-CoA metabolic process
IMCC12053_RS06305	COG2884	Cell division ATP-binding protein ftsE
IMCC12053_RS06325	COG0165	Argininosuccinate lyase
IMCC12053_RS06330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMCC12053_RS06340	COG2200	EAL domain
IMCC12053_RS06350	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC12053_RS06370	COG0142	geranyltranstransferase activity
IMCC12053_RS06375	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IMCC12053_RS06390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMCC12053_RS06430	COG1960	acyl-CoA dehydrogenase activity
IMCC12053_RS06435	COG1678	Uncharacterized ACR, COG1678
IMCC12053_RS06445	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IMCC12053_RS06455	COG0521	Mo-molybdopterin cofactor biosynthetic process
IMCC12053_RS06460	COG1573	uracil-dna glycosylase
IMCC12053_RS06465	COG0540	Belongs to the ATCase OTCase family
IMCC12053_RS06485	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IMCC12053_RS06505	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IMCC12053_RS06510	COG2885	chlorophyll binding
IMCC12053_RS06530	COG0314	molybdopterin synthase activity
IMCC12053_RS06540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMCC12053_RS06545	COG0322	excinuclease ABC activity
IMCC12053_RS06565	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IMCC12053_RS06565	COG0616	signal peptide processing
IMCC12053_RS06585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMCC12053_RS06605	COG1175	transmembrane transport
IMCC12053_RS06620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMCC12053_RS06635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMCC12053_RS06640	COG1609	Transcriptional regulator
IMCC12053_RS06665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMCC12053_RS06675	COG2801	Transposase and inactivated derivatives
IMCC12053_RS06705	COG0012	GTP binding
IMCC12053_RS06710	COG0159	tryptophan synthase activity
IMCC12053_RS06720	COG0019	diaminopimelate decarboxylase activity
IMCC12053_RS06735	COG1304	FMN binding
IMCC12053_RS06740	COG0738	Major facilitator superfamily
IMCC12053_RS06745	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IMCC12053_RS06750	COG0193	aminoacyl-tRNA hydrolase activity
IMCC12053_RS06755	COG0133	tryptophan synthase activity
IMCC12053_RS06760	COG0135	phosphoribosylanthranilate isomerase activity
IMCC12053_RS06770	COG0776	regulation of translation
IMCC12053_RS06775	COG0539	negative regulation of cytoplasmic translation
IMCC12053_RS06780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMCC12053_RS06785	COG0778	Nitroreductase
IMCC12053_RS06790	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IMCC12053_RS06800	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IMCC12053_RS06805	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMCC12053_RS06810	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IMCC12053_RS06815	COG1253	flavin adenine dinucleotide binding
IMCC12053_RS06820	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IMCC12053_RS06825	COG1702	phosphate starvation-inducible protein PhoH
IMCC12053_RS06840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMCC12053_RS06850	COG1047	Peptidyl-prolyl cis-trans
IMCC12053_RS06855	COG1357	PFAM Pentapeptide repeats (8 copies)
IMCC12053_RS06860	COG2818	Glycosylase
IMCC12053_RS06870	COG0735	belongs to the Fur family
IMCC12053_RS06875	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IMCC12053_RS06885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IMCC12053_RS06895	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IMCC12053_RS06910	COG0596	Alpha beta hydrolase
IMCC12053_RS06920	COG0596	Alpha beta hydrolase
IMCC12053_RS06935	COG1741	Belongs to the pirin family
IMCC12053_RS06940	COG1741	Belongs to the pirin family
IMCC12053_RS06955	COG0583	DNA-binding transcription factor activity
IMCC12053_RS06960	COG0583	DNA-binding transcription factor activity
IMCC12053_RS06965	COG1320	monovalent cation:proton antiporter activity
IMCC12053_RS06970	COG2212	antiporter activity
IMCC12053_RS06980	COG0651	ATP synthesis coupled electron transport
IMCC12053_RS06985	COG1006	Multisubunit Na H antiporter MnhC subunit
IMCC12053_RS06990	COG2111	Na H antiporter
IMCC12053_RS06990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMCC12053_RS07000	COG2801	Transposase and inactivated derivatives
IMCC12053_RS07035	COG4175	Glycine betaine
IMCC12053_RS07035	COG0517	IMP dehydrogenase activity
IMCC12053_RS07040	COG4176	ABC-type proline glycine betaine transport system permease component
IMCC12053_RS07050	COG1132	(ABC) transporter
IMCC12053_RS07055	COG1652	LysM domain
IMCC12053_RS07065	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC12053_RS07070	COG1841	ribosomal large subunit assembly
IMCC12053_RS07075	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMCC12053_RS07080	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IMCC12053_RS07085	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMCC12053_RS07090	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMCC12053_RS07095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMCC12053_RS07100	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IMCC12053_RS07105	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IMCC12053_RS07110	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMCC12053_RS07115	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMCC12053_RS07120	COG0255	Belongs to the universal ribosomal protein uL29 family
IMCC12053_RS07145	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IMCC12053_RS07150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMCC12053_RS07155	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IMCC12053_RS07160	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IMCC12053_RS07165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IMCC12053_RS07170	COG0089	rRNA binding
IMCC12053_RS07175	COG0088	Forms part of the polypeptide exit tunnel
IMCC12053_RS07180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMCC12053_RS07185	COG0051	transcription antitermination factor activity, RNA binding
IMCC12053_RS07190	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMCC12053_RS07195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMCC12053_RS07200	COG0049	tRNA binding
IMCC12053_RS07205	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMCC12053_RS07220	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMCC12053_RS07225	COG0085	RNA polymerase activity
IMCC12053_RS07230	COG0222	ribosome binding
IMCC12053_RS07235	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IMCC12053_RS07240	COG0081	regulation of translation
IMCC12053_RS07245	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IMCC12053_RS07260	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMCC12053_RS07280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMCC12053_RS07290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMCC12053_RS07300	COG0300	oxidoreductase activity
IMCC12053_RS07310	COG2096	Adenosyltransferase
IMCC12053_RS07330	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMCC12053_RS07350	COG1660	Displays ATPase and GTPase activities
IMCC12053_RS07360	COG2205	protein histidine kinase activity
IMCC12053_RS07365	COG0745	RESPONSE REGULATOR receiver
IMCC12053_RS07370	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IMCC12053_RS07395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IMCC12053_RS07405	COG0681	Belongs to the peptidase S26 family
IMCC12053_RS07410	COG0736	holo-[acyl-carrier-protein] synthase activity
IMCC12053_RS07415	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IMCC12053_RS07425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMCC12053_RS07435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMCC12053_RS07445	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IMCC12053_RS07455	COG0328	RNA-DNA hybrid ribonuclease activity
IMCC12053_RS07460	COG2860	membrane
IMCC12053_RS07475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMCC12053_RS07490	COG0242	peptide deformylase activity
IMCC12053_RS07495	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IMCC12053_RS07545	COG0435	Glutathione S-transferase
IMCC12053_RS07560	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IMCC12053_RS07615	COG1380	Effector of murein hydrolase LrgA
IMCC12053_RS07620	COG1346	cytolysis
IMCC12053_RS07635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMCC12053_RS07635	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IMCC12053_RS07650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMCC12053_RS07660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IMCC12053_RS07680	COG0004	ammonium transporteR
IMCC12053_RS07685	COG0347	Belongs to the P(II) protein family
IMCC12053_RS07730	COG2154	pterin-4-alpha-carbinolamine dehydratase
IMCC12053_RS07735	COG0668	transmembrane transport
IMCC12053_RS07740	COG0678	peroxiredoxin activity
IMCC12053_RS07750	COG0742	ribosomal rna small subunit methyltransferase
IMCC12053_RS07755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMCC12053_RS07760	COG0285	dihydrofolate synthase activity
IMCC12053_RS07765	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IMCC12053_RS07790	COG1902	pentaerythritol trinitrate reductase activity
IMCC12053_RS07790	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMCC12053_RS07795	COG0583	DNA-binding transcription factor activity
IMCC12053_RS07805	COG1058	Belongs to the CinA family
IMCC12053_RS07805	COG1546	Belongs to the CinA family
IMCC12053_RS07810	COG1489	DNA binding
IMCC12053_RS07815	COG0024	Methionine aminopeptidase
IMCC12053_RS07820	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMCC12053_RS07825	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IMCC12053_RS07840	COG1671	Belongs to the UPF0178 family
IMCC12053_RS07860	COG0791	NLP P60 protein
IMCC12053_RS07865	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMCC12053_RS07875	COG0288	reversible hydration of carbon dioxide
IMCC12053_RS07890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IMCC12053_RS07930	COG1054	Belongs to the UPF0176 family
IMCC12053_RS07935	COG0443	Heat shock 70 kDa protein
IMCC12053_RS07940	COG1335	isochorismatase
IMCC12053_RS07950	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IMCC12053_RS07965	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IMCC12053_RS07980	COG2270	Major facilitator Superfamily
IMCC12053_RS07995	COG0514	ATP-dependent DNA helicase (RecQ)
IMCC12053_RS08000	COG2205	protein histidine kinase activity
IMCC12053_RS08000	COG5002	protein histidine kinase activity
IMCC12053_RS08000	COG0784	Response regulator, receiver
IMCC12053_RS08020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IMCC12053_RS08030	COG0560	Phosphoserine phosphatase
IMCC12053_RS08050	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IMCC12053_RS08095	COG0557	exoribonuclease II activity
IMCC12053_RS08100	COG2951	lytic endotransglycosylase activity
IMCC12053_RS08110	COG0793	Belongs to the peptidase S41A family
IMCC12053_RS08120	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IMCC12053_RS08125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IMCC12053_RS08130	COG0799	negative regulation of ribosome biogenesis
IMCC12053_RS08135	COG3264	Mechanosensitive ion channel
IMCC12053_RS08135	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IMCC12053_RS08140	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMCC12053_RS08145	COG0066	3-isopropylmalate dehydratase activity
IMCC12053_RS08155	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IMCC12053_RS08170	COG0473	3-isopropylmalate dehydrogenase activity
IMCC12053_RS08180	COG0697	spore germination
IMCC12053_RS08185	COG1454	alcohol dehydrogenase
IMCC12053_RS08190	COG1609	Transcriptional regulator
IMCC12053_RS08195	COG2084	Dehydrogenase
IMCC12053_RS08200	COG3395	kinase activity
IMCC12053_RS08205	COG0235	Class ii aldolase
IMCC12053_RS08210	COG3622	Belongs to the hyi family
IMCC12053_RS08220	COG1280	lysine exporter protein (LysE YggA)
IMCC12053_RS08225	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMCC12053_RS08235	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IMCC12053_RS08240	COG0268	Binds directly to 16S ribosomal RNA
IMCC12053_RS08250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IMCC12053_RS08255	COG2226	methyltransferase
IMCC12053_RS08270	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IMCC12053_RS08300	COG5443	negative regulation of bacterial-type flagellum assembly
IMCC12053_RS08315	COG1815	bacterial-type flagellum-dependent cell motility
IMCC12053_RS08320	COG1558	bacterial-type flagellum-dependent cell motility
IMCC12053_RS08325	COG1677	Flagellar hook-basal body complex protein FliE
IMCC12053_RS08330	COG1987	bacterial-type flagellum assembly
IMCC12053_RS08335	COG4786	Flagellar basal body rod
IMCC12053_RS08340	COG4786	Flagellar basal body rod
IMCC12053_RS08350	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IMCC12053_RS08365	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IMCC12053_RS08375	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IMCC12053_RS08405	COG1766	The M ring may be actively involved in energy transduction
IMCC12053_RS08415	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IMCC12053_RS08420	COG1338	Plays a role in the flagellum-specific transport system
IMCC12053_RS08435	COG1999	signal sequence binding
IMCC12053_RS08440	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IMCC12053_RS08445	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IMCC12053_RS08450	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IMCC12053_RS08470	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IMCC12053_RS08495	COG0033	Phosphoglucomutase
IMCC12053_RS08505	COG1749	Flagellar hook protein flgE
IMCC12053_RS08520	COG1706	bacterial-type flagellum-dependent cell motility
IMCC12053_RS08525	COG2801	Transposase and inactivated derivatives
IMCC12053_RS08535	COG3178	'Phosphotransferase
IMCC12053_RS08540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IMCC12053_RS08545	COG2887	Belongs to the helicase family. UvrD subfamily
IMCC12053_RS08550	COG1074	ATP-dependent DNA helicase activity
IMCC12053_RS08560	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IMCC12053_RS08565	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IMCC12053_RS08580	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IMCC12053_RS08590	COG3030	protein affecting phage T7 exclusion by the F plasmid
IMCC12053_RS08595	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IMCC12053_RS08600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMCC12053_RS08605	COG0237	dephospho-CoA kinase activity
IMCC12053_RS08615	COG0424	maF-like protein
IMCC12053_RS08620	COG1981	membrane
IMCC12053_RS08625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IMCC12053_RS08630	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IMCC12053_RS08635	COG0445	tRNA wobble uridine modification
IMCC12053_RS08640	COG0357	Ribosomal RNA small subunit methyltransferase G
IMCC12053_RS08655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IMCC12053_RS08660	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMCC12053_RS08665	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IMCC12053_RS08670	COG1420	regulation of RNA biosynthetic process
IMCC12053_RS08675	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IMCC12053_RS08680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IMCC12053_RS08685	COG0281	malic enzyme
IMCC12053_RS08685	COG0280	phosphate acetyltransferase
IMCC12053_RS08695	COG0137	argininosuccinate synthase activity
IMCC12053_RS08705	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMCC12053_RS08725	COG0494	nUDIX hydrolase
IMCC12053_RS08730	COG0617	tRNA 3'-terminal CCA addition
IMCC12053_RS08735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMCC12053_RS08740	COG3034	peptidoglycan biosynthetic process
IMCC12053_RS08760	COG2226	methyltransferase
IMCC12053_RS08765	COG1040	competence protein
IMCC12053_RS08775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMCC12053_RS08785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IMCC12053_RS08795	COG0779	Required for maturation of 30S ribosomal subunits
IMCC12053_RS08810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMCC12053_RS08815	COG0494	nUDIX hydrolase
IMCC12053_RS08820	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IMCC12053_RS08825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMCC12053_RS08830	COG0653	protein targeting
IMCC12053_RS08840	COG0582	viral genome integration into host DNA
IMCC12053_RS08855	COG2003	Belongs to the UPF0758 family
IMCC12053_RS08865	COG0443	Heat shock 70 kDa protein
IMCC12053_RS08880	COG1218	3'(2'),5'-bisphosphate nucleotidase
IMCC12053_RS08885	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IMCC12053_RS08890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IMCC12053_RS08920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMCC12053_RS08925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IMCC12053_RS08930	COG1137	ATPase activity
IMCC12053_RS08965	COG1968	undecaprenyl-diphosphatase activity
IMCC12053_RS08980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMCC12053_RS08990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IMCC12053_RS09005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMCC12053_RS09010	COG1846	Transcriptional regulator
IMCC12053_RS09015	COG0745	RESPONSE REGULATOR receiver
IMCC12053_RS09025	COG0142	geranyltranstransferase activity
IMCC12053_RS09030	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IMCC12053_RS09040	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IMCC12053_RS09045	COG0776	regulation of translation
IMCC12053_RS09050	COG0697	spore germination
IMCC12053_RS09055	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMCC12053_RS09060	COG4143	(ABC) transporter
IMCC12053_RS09070	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IMCC12053_RS09095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMCC12053_RS09100	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IMCC12053_RS09110	COG0129	dihydroxy-acid dehydratase activity
IMCC12053_RS09115	COG1609	Transcriptional regulator
IMCC12053_RS09135	COG3451	type IV secretory pathway VirB4
IMCC12053_RS09160	COG1349	DNA-binding transcription factor activity
IMCC12053_RS09165	COG0149	triose-phosphate isomerase activity
IMCC12053_RS09190	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMCC12053_RS09205	COG1194	a g-specific adenine glycosylase
IMCC12053_RS09220	COG1663	tetraacyldisaccharide 4'-kinase activity
IMCC12053_RS09240	COG1215	transferase activity, transferring glycosyl groups
IMCC12053_RS09250	COG0312	modulator of DNA gyrase
IMCC12053_RS09265	COG2081	HI0933 family
IMCC12053_RS09280	COG0495	leucyl-tRNA aminoacylation
IMCC12053_RS09295	COG0582	viral genome integration into host DNA
IMCC12053_RS09320	COG4974	Belongs to the 'phage' integrase family
IMCC12053_RS09330	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMCC12053_RS09345	COG0745	RESPONSE REGULATOR receiver
IMCC12053_RS09365	COG2835	tetraacyldisaccharide 4'-kinase activity
IMCC12053_RS09370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMCC12053_RS09380	COG0436	Aminotransferase
IMCC12053_RS09385	COG1674	ftsk spoiiie
IMCC12053_RS09425	COG0564	pseudouridine synthase activity
IMCC12053_RS09430	COG0450	alkyl hydroperoxide reductase
IMCC12053_RS09435	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IMCC12053_RS09440	COG3475	LICD family
IMCC12053_RS09445	COG1185	polyribonucleotide nucleotidyltransferase activity
IMCC12053_RS09470	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IMCC12053_RS09490	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMCC12053_RS09495	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMCC12053_RS09500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IMCC12053_RS09515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IMCC12053_RS09515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMCC12053_RS09525	COG0138	bifunctional purine biosynthesis protein purh
IMCC12053_RS09530	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMCC12053_RS09540	COG0612	Peptidase, M16
IMCC12053_RS09545	COG0612	Peptidase, M16
IMCC12053_RS09550	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IMCC12053_RS09570	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IMCC12053_RS09585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMCC12053_RS09590	COG0284	orotidine-5'-phosphate decarboxylase activity
IMCC12053_RS09610	COG0069	glutamate synthase activity
IMCC12053_RS09615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IMCC12053_RS09620	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
IMCC12053_RS09660	COG2801	Transposase and inactivated derivatives
IMCC12053_RS09670	COG2801	Transposase and inactivated derivatives
IMCC12053_RS09675	COG1129	ABC transporter
IMCC12053_RS09680	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS09685	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS09690	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC12053_RS09695	COG1879	ABC-type sugar transport system periplasmic component
IMCC12053_RS09700	COG1653	transport
IMCC12053_RS09710	COG0006	proline dipeptidase activity
IMCC12053_RS09715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IMCC12053_RS09720	COG0022	dehydrogenase e1 component
IMCC12053_RS09725	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC12053_RS09740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMCC12053_RS09745	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC12053_RS09815	COG3657	addiction module killer protein
IMCC12053_RS09820	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IMCC12053_RS09845	COG3093	addiction module antidote protein HigA
IMCC12053_RS09885	COG3609	addiction module antidote protein, CC2985 family
IMCC12053_RS09910	COG0740	serine-type endopeptidase activity
IMCC12053_RS10070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMCC12053_RS10075	COG3264	Mechanosensitive ion channel
IMCC12053_RS10075	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IMCC12053_RS10095	COG0785	Cytochrome C biogenesis protein
IMCC12053_RS10100	COG1530	ribonuclease E activity
IMCC12053_RS10105	COG2204	response regulator
IMCC12053_RS10115	COG0047	phosphoribosylformylglycinamidine synthase activity
IMCC12053_RS10125	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMCC12053_RS10130	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IMCC12053_RS10145	COG1410	methionine synthase
IMCC12053_RS10145	COG0646	methionine synthase
IMCC12053_RS10150	COG5012	cobalamin binding
IMCC12053_RS10160	COG2166	iron-sulfur cluster assembly
IMCC12053_RS10175	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IMCC12053_RS10195	COG0697	spore germination
IMCC12053_RS10220	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IMCC12053_RS10225	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMCC12053_RS10245	COG0126	phosphoglycerate kinase activity
IMCC12053_RS10255	COG1830	Aldolase
IMCC12053_RS10265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IMCC12053_RS10270	COG0022	dehydrogenase e1 component
IMCC12053_RS10270	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC12053_RS10275	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC12053_RS10355	COG4695	Portal protein
IMCC12053_RS10370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMCC12053_RS10375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IMCC12053_RS10385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMCC12053_RS10395	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IMCC12053_RS10415	COG0360	Binds together with S18 to 16S ribosomal RNA
IMCC12053_RS10420	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMCC12053_RS10425	COG0359	binds to the 23S rRNA
IMCC12053_RS10435	COG0544	peptidyl-prolyl cis-trans isomerase activity
IMCC12053_RS10445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMCC12053_RS10470	COG0259	pyridoxamine-phosphate oxidase activity
IMCC12053_RS10475	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IMCC12053_RS10485	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IMCC12053_RS10500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMCC12053_RS10505	COG1522	sequence-specific DNA binding
IMCC12053_RS10515	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMCC12053_RS10520	COG0175	sulfate reduction
IMCC12053_RS10535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMCC12053_RS10550	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IMCC12053_RS10555	COG1024	Enoyl-CoA hydratase
IMCC12053_RS10555	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMCC12053_RS10580	COG5002	protein histidine kinase activity
IMCC12053_RS10590	COG0745	RESPONSE REGULATOR receiver
IMCC12053_RS10610	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS10620	COG0410	ABC transporter
IMCC12053_RS10625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMCC12053_RS10645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMCC12053_RS10650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMCC12053_RS10665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IMCC12053_RS10675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMCC12053_RS10680	COG1309	transcriptional regulator
IMCC12053_RS10690	COG0167	dihydroorotate dehydrogenase activity
IMCC12053_RS10690	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IMCC12053_RS10695	COG0493	'glutamate synthase
IMCC12053_RS10700	COG0511	ligase activity, forming carbon-carbon bonds
IMCC12053_RS10710	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IMCC12053_RS10735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMCC12053_RS10740	COG0740	serine-type endopeptidase activity
IMCC12053_RS10770	COG3959	Transketolase, thiamine diphosphate binding domain
IMCC12053_RS10775	COG3958	Transketolase
IMCC12053_RS10780	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC12053_RS10785	COG0583	DNA-binding transcription factor activity
IMCC12053_RS10790	COG1802	Transcriptional regulator
IMCC12053_RS10805	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC12053_RS10810	COG2721	sulfolactate sulfo-lyase activity
IMCC12053_RS10815	COG0697	spore germination
IMCC12053_RS10820	COG0300	oxidoreductase activity
IMCC12053_RS10825	COG0129	dihydroxy-acid dehydratase activity
IMCC12053_RS10840	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC12053_RS10845	COG1063	alcohol dehydrogenase
IMCC12053_RS10860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC12053_RS10870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMCC12053_RS10880	COG1858	cytochrome C peroxidase
IMCC12053_RS10895	COG0392	lysyltransferase activity
IMCC12053_RS10895	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IMCC12053_RS10935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IMCC12053_RS10960	COG0673	inositol 2-dehydrogenase activity
IMCC12053_RS10965	COG0673	inositol 2-dehydrogenase activity
IMCC12053_RS10970	COG0673	inositol 2-dehydrogenase activity
IMCC12053_RS10975	COG0673	inositol 2-dehydrogenase activity
IMCC12053_RS10980	COG3842	ATPase activity
IMCC12053_RS10985	COG0395	ABC-type sugar transport system, permease component
IMCC12053_RS10990	COG1175	transmembrane transport
IMCC12053_RS11000	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IMCC12053_RS11020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IMCC12053_RS11030	COG1216	Glycosyl transferase, family 2
IMCC12053_RS11035	COG0343	queuine tRNA-ribosyltransferase activity
IMCC12053_RS11040	COG4067	protein conserved in archaea
IMCC12053_RS11040	COG0189	ligase activity
IMCC12053_RS11045	COG2151	metal-sulfur cluster biosynthetic enzyme
IMCC12053_RS11060	COG0149	triose-phosphate isomerase activity
IMCC12053_RS11065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMCC12053_RS11110	COG0501	Belongs to the peptidase M48B family
IMCC12053_RS11115	COG1569	PIN domain
IMCC12053_RS11125	COG0129	dihydroxy-acid dehydratase activity
IMCC12053_RS11135	COG0800	Aldolase
IMCC12053_RS11145	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IMCC12053_RS11165	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IMCC12053_RS11185	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IMCC12053_RS11210	COG0028	Belongs to the TPP enzyme family
IMCC12053_RS11230	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC12053_RS11240	COG3842	ATPase activity
IMCC12053_RS11265	COG1175	transmembrane transport
IMCC12053_RS11270	COG0395	ABC-type sugar transport system, permease component
IMCC12053_RS11280	COG4952	isomerase
IMCC12053_RS11285	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC12053_RS11285	COG3347	Dehydrogenase
IMCC12053_RS11295	COG1879	ABC-type sugar transport system periplasmic component
IMCC12053_RS11300	COG1129	ABC transporter
IMCC12053_RS11305	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS11310	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS11315	COG3254	rhamnose metabolic process
IMCC12053_RS11325	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
IMCC12053_RS11330	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IMCC12053_RS11335	COG0582	viral genome integration into host DNA
IMCC12053_RS11355	COG0667	Aldo Keto reductase
IMCC12053_RS11365	COG2376	Dihydroxyacetone kinase
IMCC12053_RS11375	COG1129	ABC transporter
IMCC12053_RS11385	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS11390	COG1609	Transcriptional regulator
IMCC12053_RS11395	COG1069	ribulokinase activity
IMCC12053_RS11405	COG2801	Transposase and inactivated derivatives
IMCC12053_RS11405	COG3415	Transposase
IMCC12053_RS11425	COG1686	Belongs to the peptidase S11 family
IMCC12053_RS11430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IMCC12053_RS11440	COG0084	hydrolase, TatD family'
IMCC12053_RS11445	COG1234	tRNA 3'-trailer cleavage
IMCC12053_RS11465	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IMCC12053_RS11475	COG2376	Dihydroxyacetone kinase
IMCC12053_RS11480	COG0642	Histidine kinase
IMCC12053_RS11500	COG3239	Fatty acid desaturase
IMCC12053_RS11505	COG3608	succinylglutamate desuccinylase aspartoacylase
IMCC12053_RS11535	COG2801	Transposase and inactivated derivatives
IMCC12053_RS11560	COG3265	gluconokinase activity
IMCC12053_RS11580	COG3750	Belongs to the UPF0335 family
IMCC12053_RS11605	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IMCC12053_RS11620	COG0804	urea catabolic process
IMCC12053_RS11630	COG0832	Belongs to the urease beta subunit family
IMCC12053_RS11635	COG0831	urea catabolic process
IMCC12053_RS11640	COG0829	nickel cation binding
IMCC12053_RS11645	COG0418	dihydroorotase activity
IMCC12053_RS11650	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IMCC12053_RS11655	COG0305	Participates in initiation and elongation during chromosome replication
IMCC12053_RS11660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMCC12053_RS11665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IMCC12053_RS11670	COG1127	ABC transporter
IMCC12053_RS11700	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IMCC12053_RS11710	COG4221	oxidoreductase activity
IMCC12053_RS11720	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IMCC12053_RS11725	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IMCC12053_RS11740	COG0805	protein transport
IMCC12053_RS11750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMCC12053_RS11765	COG3842	ATPase activity
IMCC12053_RS11770	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC12053_RS11780	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IMCC12053_RS11790	COG0513	Belongs to the DEAD box helicase family
IMCC12053_RS11805	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IMCC12053_RS11815	COG1007	ATP synthesis coupled electron transport
IMCC12053_RS11830	COG0713	ATP synthesis coupled electron transport
IMCC12053_RS11845	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC12053_RS11850	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IMCC12053_RS11880	COG3743	rRNA binding
IMCC12053_RS11880	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IMCC12053_RS11890	COG0649	NAD binding
IMCC12053_RS11895	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC12053_RS11900	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC12053_RS11910	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMCC12053_RS11915	COG0546	phosphoglycolate phosphatase activity
IMCC12053_RS11920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMCC12053_RS11935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IMCC12053_RS11940	COG1473	amidohydrolase
IMCC12053_RS11945	COG2391	methyltransferase activity
IMCC12053_RS11960	COG0785	Cytochrome C biogenesis protein
IMCC12053_RS11965	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IMCC12053_RS11985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IMCC12053_RS11990	COG0308	aminopeptidase N
IMCC12053_RS11995	COG1063	alcohol dehydrogenase
IMCC12053_RS12000	COG3909	cytochrome
IMCC12053_RS12020	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IMCC12053_RS12030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMCC12053_RS12035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IMCC12053_RS12040	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IMCC12053_RS12045	COG3409	Peptidoglycan-binding domain 1 protein
IMCC12053_RS12045	COG3773	Cell wall hydrolase
IMCC12053_RS12050	COG0574	Belongs to the PEP-utilizing enzyme family
IMCC12053_RS12050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMCC12053_RS12055	COG0751	glycine-tRNA ligase activity
IMCC12053_RS12065	COG0752	glycyl-tRNA synthetase alpha subunit
IMCC12053_RS12075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMCC12053_RS12090	COG1469	GTP cyclohydrolase I activity
IMCC12053_RS12100	COG0625	glutathione transferase activity
IMCC12053_RS12125	COG0552	protein localization to endoplasmic reticulum
IMCC12053_RS12145	COG1570	exodeoxyribonuclease VII activity
IMCC12053_RS12175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMCC12053_RS12180	COG0330	HflC and HflK could
IMCC12053_RS12185	COG0330	HflC and HflK could
IMCC12053_RS12195	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IMCC12053_RS12215	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IMCC12053_RS12225	COG0504	CTP synthase activity
IMCC12053_RS12230	COG1760	l-serine dehydratase
IMCC12053_RS12235	COG2808	Putative FMN-binding domain
IMCC12053_RS12255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMCC12053_RS12260	COG4215	(ABC) transporter
IMCC12053_RS12270	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMCC12053_RS12270	COG0519	Catalyzes the synthesis of GMP from XMP
IMCC12053_RS12275	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMCC12053_RS12280	COG0583	DNA-binding transcription factor activity
IMCC12053_RS12295	COG3243	poly(R)-hydroxyalkanoic acid synthase
IMCC12053_RS12315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMCC12053_RS12325	COG3220	belongs to the UPF0276 family
IMCC12053_RS12340	COG1393	Belongs to the ArsC family
IMCC12053_RS12365	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IMCC12053_RS12385	COG1846	Transcriptional regulator
IMCC12053_RS12405	COG0534	Mate efflux family protein
IMCC12053_RS12410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMCC12053_RS12425	COG0667	Aldo Keto reductase
IMCC12053_RS12430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMCC12053_RS12455	COG0483	inositol monophosphate 1-phosphatase activity
IMCC12053_RS12460	COG0583	DNA-binding transcription factor activity
IMCC12053_RS12465	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IMCC12053_RS12490	COG0525	valine-tRNA ligase activity
IMCC12053_RS12495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IMCC12053_RS12500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IMCC12053_RS12505	COG1132	(ABC) transporter
IMCC12053_RS12515	COG0354	folic acid binding
IMCC12053_RS12520	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMCC12053_RS12530	COG1492	cobalamin metabolic process
IMCC12053_RS12545	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IMCC12053_RS12555	COG0582	viral genome integration into host DNA
IMCC12053_RS12640	COG1129	ABC transporter
IMCC12053_RS12665	COG0667	Aldo Keto reductase
IMCC12053_RS12690	COG2963	transposase activity
IMCC12053_RS12715	COG3718	enzyme involved in inositol metabolism
IMCC12053_RS12725	COG3962	Belongs to the TPP enzyme family
IMCC12053_RS12730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC12053_RS12740	COG0673	inositol 2-dehydrogenase activity
IMCC12053_RS12745	COG1082	Xylose isomerase domain protein TIM barrel
IMCC12053_RS12755	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS12770	COG1609	Transcriptional regulator
IMCC12053_RS12775	COG0673	inositol 2-dehydrogenase activity
IMCC12053_RS12785	COG0673	inositol 2-dehydrogenase activity
IMCC12053_RS12790	COG0673	inositol 2-dehydrogenase activity
IMCC12053_RS12835	COG1477	protein flavinylation
IMCC12053_RS12855	COG2801	Transposase and inactivated derivatives
IMCC12053_RS12860	COG3550	peptidyl-serine autophosphorylation
IMCC12053_RS12920	COG1519	Transferase
IMCC12053_RS12945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMCC12053_RS12970	COG0659	secondary active sulfate transmembrane transporter activity
IMCC12053_RS12975	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IMCC12053_RS12980	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMCC12053_RS13000	COG0612	Peptidase, M16
IMCC12053_RS13020	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IMCC12053_RS13030	COG0109	protoheme IX farnesyltransferase activity
IMCC12053_RS13040	COG0312	modulator of DNA gyrase
IMCC12053_RS13045	COG0697	spore germination
IMCC12053_RS13050	COG0758	DNA mediated transformation
IMCC12053_RS13055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMCC12053_RS13085	COG0277	FAD linked oxidase domain protein
IMCC12053_RS13095	COG0741	lytic transglycosylase activity
IMCC12053_RS13115	COG4964	Belongs to the GSP D family
IMCC12053_RS13170	COG2084	Dehydrogenase
IMCC12053_RS13175	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMCC12053_RS13180	COG0287	Prephenate dehydrogenase
IMCC12053_RS13180	COG1605	Chorismate mutase
IMCC12053_RS13185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMCC12053_RS13190	COG0037	tRNA processing
IMCC12053_RS13200	COG2885	chlorophyll binding
IMCC12053_RS13205	COG0823	Involved in the tonB-independent uptake of proteins
IMCC12053_RS13215	COG0848	biopolymer transport protein
IMCC12053_RS13225	COG0824	Thioesterase
IMCC12053_RS13235	COG2255	four-way junction helicase activity
IMCC12053_RS13240	COG0632	four-way junction helicase activity
IMCC12053_RS13255	COG2264	protein methyltransferase activity
IMCC12053_RS13260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMCC12053_RS13270	COG2391	methyltransferase activity
IMCC12053_RS13280	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMCC12053_RS13295	COG1183	phosphatidylcholine synthase activity
IMCC12053_RS13310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMCC12053_RS13320	COG3768	UPF0283 membrane protein
IMCC12053_RS13325	COG3106	COG3106 Predicted ATPase
IMCC12053_RS13330	COG0101	tRNA pseudouridine synthase activity
IMCC12053_RS13340	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IMCC12053_RS13345	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IMCC12053_RS13365	COG3383	formate dehydrogenase (NAD+) activity
IMCC12053_RS13370	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IMCC12053_RS13400	COG1072	(Pantothenic acid kinase))
IMCC12053_RS13405	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IMCC12053_RS13430	COG1312	Catalyzes the dehydration of D-mannonate
IMCC12053_RS13440	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IMCC12053_RS13445	COG3257	ureidoglycine aminohydrolase activity
IMCC12053_RS13455	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IMCC12053_RS13465	COG2351	hydroxyisourate hydrolase activity
IMCC12053_RS13480	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IMCC12053_RS13480	COG0546	phosphoglycolate phosphatase activity
IMCC12053_RS13490	COG0737	Belongs to the 5'-nucleotidase family
IMCC12053_RS13495	COG1309	transcriptional regulator
IMCC12053_RS13515	COG0534	Mate efflux family protein
IMCC12053_RS13540	COG1960	acyl-CoA dehydrogenase activity
IMCC12053_RS13560	COG0183	Belongs to the thiolase family
IMCC12053_RS13565	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMCC12053_RS13565	COG1024	Enoyl-CoA hydratase
IMCC12053_RS13590	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMCC12053_RS13595	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IMCC12053_RS13600	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IMCC12053_RS13625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IMCC12053_RS13655	COG0642	Histidine kinase
IMCC12053_RS13670	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC12053_RS13680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMCC12053_RS13690	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMCC12053_RS13710	COG5002	protein histidine kinase activity
IMCC12053_RS13710	COG2176	DNA-directed DNA polymerase activity
IMCC12053_RS13720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMCC12053_RS13725	COG1132	(ABC) transporter
IMCC12053_RS13740	COG2217	Heavy metal translocating P-type atpase
IMCC12053_RS13750	COG3734	2-keto-3-deoxy-galactonokinase
IMCC12053_RS13755	COG0800	Aldolase
IMCC12053_RS13795	COG0556	nucleotide-excision repair
IMCC12053_RS13830	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IMCC12053_RS13845	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMCC12053_RS13855	COG0488	(ABC) transporter
IMCC12053_RS13875	COG1278	Cold shock
IMCC12053_RS13885	COG0729	surface antigen
IMCC12053_RS13895	COG3118	belongs to the thioredoxin family
IMCC12053_RS13905	COG0509	glycine decarboxylation via glycine cleavage system
IMCC12053_RS13910	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMCC12053_RS13915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMCC12053_RS13940	COG3046	protein related to deoxyribodipyrimidine photolyase
IMCC12053_RS13950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC12053_RS13970	COG0768	penicillin binding
IMCC12053_RS13975	COG0772	Belongs to the SEDS family
IMCC12053_RS13980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IMCC12053_RS14025	COG0163	prenyltransferase activity
IMCC12053_RS14030	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IMCC12053_RS14035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IMCC12053_RS14050	COG0582	viral genome integration into host DNA
IMCC12053_RS14085	COG2026	Addiction module toxin, RelE StbE family
IMCC12053_RS14095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMCC12053_RS14105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMCC12053_RS14110	COG5328	Belongs to the UPF0262 family
IMCC12053_RS14120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IMCC12053_RS14130	COG1530	ribonuclease E activity
IMCC12053_RS14135	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IMCC12053_RS14180	COG0517	IMP dehydrogenase activity
IMCC12053_RS14185	COG4974	Belongs to the 'phage' integrase family
IMCC12053_RS14220	COG2132	Multicopper oxidase
IMCC12053_RS14270	COG4974	Belongs to the 'phage' integrase family
IMCC12053_RS14320	COG2089	acid synthase
IMCC12053_RS14330	COG1083	cytidylyl-transferase
IMCC12053_RS14345	COG1086	Polysaccharide biosynthesis protein
IMCC12053_RS14405	COG2801	Transposase and inactivated derivatives
IMCC12053_RS14410	COG2963	transposase activity
IMCC12053_RS14420	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IMCC12053_RS14435	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IMCC12053_RS14440	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IMCC12053_RS14445	COG0124	histidyl-tRNA synthetase
IMCC12053_RS14475	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IMCC12053_RS14485	COG3845	ABC transporter
IMCC12053_RS14490	COG4603	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS14495	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS14505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IMCC12053_RS14515	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IMCC12053_RS14520	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IMCC12053_RS14525	COG1741	Belongs to the pirin family
IMCC12053_RS14530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMCC12053_RS14545	COG0339	signal peptide processing
IMCC12053_RS14550	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IMCC12053_RS14555	COG0756	dUTP diphosphatase activity
IMCC12053_RS14560	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMCC12053_RS14585	COG0606	chelatase, subunit chli
IMCC12053_RS14595	COG0792	nuclease activity
IMCC12053_RS14600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IMCC12053_RS14610	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IMCC12053_RS14615	COG0728	peptidoglycan biosynthetic process
IMCC12053_RS14625	COG0180	Tryptophanyl-tRNA synthetase
IMCC12053_RS14635	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IMCC12053_RS14645	COG1744	ABC transporter substrate-binding protein PnrA-like
IMCC12053_RS14650	COG3845	ABC transporter
IMCC12053_RS14655	COG4603	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS14660	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS14665	COG0730	response to heat
IMCC12053_RS14695	COG0604	alcohol dehydrogenase
IMCC12053_RS14700	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMCC12053_RS14700	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMCC12053_RS14710	COG0813	purine-nucleoside phosphorylase activity
IMCC12053_RS14715	COG0667	Aldo Keto reductase
IMCC12053_RS14745	COG2030	dehydratase
IMCC12053_RS14760	COG2301	Belongs to the HpcH HpaI aldolase family
IMCC12053_RS14770	COG0039	L-malate dehydrogenase activity
IMCC12053_RS14780	COG0045	succinate-CoA ligase (ADP-forming) activity
IMCC12053_RS14790	COG0567	Dehydrogenase, E1 component
IMCC12053_RS14795	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC12053_RS14810	COG1607	acyl-coa hydrolase
IMCC12053_RS14850	COG1126	abc transporter atp-binding protein
IMCC12053_RS14855	COG0765	amino acid transport
IMCC12053_RS14890	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IMCC12053_RS14895	COG0594	ribonuclease P activity
IMCC12053_RS14900	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IMCC12053_RS14905	COG0037	tRNA processing
IMCC12053_RS14910	COG5001	Diguanylate cyclase
IMCC12053_RS14915	COG0706	membrane insertase activity
IMCC12053_RS14920	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IMCC12053_RS14925	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IMCC12053_RS14935	COG1126	abc transporter atp-binding protein
IMCC12053_RS14940	COG0765	amino acid transport
IMCC12053_RS14945	COG4597	amino acid ABC transporter
IMCC12053_RS14950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMCC12053_RS14960	COG0546	phosphoglycolate phosphatase activity
IMCC12053_RS14965	COG0564	pseudouridine synthase activity
IMCC12053_RS14975	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IMCC12053_RS14990	COG0202	RNA polymerase activity
IMCC12053_RS14995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMCC12053_RS15000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMCC12053_RS15005	COG0563	adenylate kinase activity
IMCC12053_RS15010	COG0201	protein transport
IMCC12053_RS15015	COG0200	Binds to the 23S rRNA
IMCC12053_RS15025	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IMCC12053_RS15030	COG1510	regulation of RNA biosynthetic process
IMCC12053_RS15040	COG1566	PFAM secretion protein HlyD family protein
IMCC12053_RS15045	COG3620	sequence-specific DNA binding
IMCC12053_RS15050	COG0747	negative chemotaxis
IMCC12053_RS15055	COG0006	proline dipeptidase activity
IMCC12053_RS15060	COG0601	transmembrane transport
IMCC12053_RS15065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC12053_RS15070	COG0444	Belongs to the ABC transporter superfamily
IMCC12053_RS15075	COG4608	Belongs to the ABC transporter superfamily
IMCC12053_RS15085	COG1802	Transcriptional regulator
IMCC12053_RS15090	COG2721	sulfolactate sulfo-lyase activity
IMCC12053_RS15095	COG1129	ABC transporter
IMCC12053_RS15100	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC12053_RS15105	COG1879	ABC-type sugar transport system periplasmic component
IMCC12053_RS15115	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IMCC12053_RS15130	COG3842	ATPase activity
IMCC12053_RS15135	COG0395	ABC-type sugar transport system, permease component
IMCC12053_RS15140	COG1175	transmembrane transport
IMCC12053_RS15160	COG2963	transposase activity
IMCC12053_RS15165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IMCC12053_RS15175	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IMCC12053_RS15220	COG1522	sequence-specific DNA binding
IMCC12053_RS15230	COG0582	viral genome integration into host DNA
IMCC12053_RS15280	COG1475	DNA binding
IMCC12053_RS15430	COG2026	Addiction module toxin, RelE StbE family