locus-tag	class	description
GXP71_RS00010	COG3693	PFAM glycoside hydrolase, family 10
GXP71_RS00050	COG1316	TRANSCRIPTIONal
GXP71_RS00060	COG1937	Protein conserved in bacteria
GXP71_RS00065	COG0446	pyridine nucleotide-disulphide oxidoreductase
GXP71_RS00090	COG2390	Transcriptional regulator
GXP71_RS00095	COG1172	Belongs to the binding-protein-dependent transport system permease family
GXP71_RS00105	COG1129	ABC transporter
GXP71_RS00115	COG1070	Carbohydrate kinase
GXP71_RS00120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GXP71_RS00140	COG1940	carbohydrate kinase activity
GXP71_RS00145	COG4214	carbohydrate transport
GXP71_RS00160	COG0534	Mate efflux family protein
GXP71_RS00170	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GXP71_RS00175	COG0254	rRNA binding
GXP71_RS00180	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GXP71_RS00185	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GXP71_RS00190	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GXP71_RS00195	COG0523	cobalamin synthesis protein
GXP71_RS00225	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GXP71_RS00245	COG4932	domain protein
GXP71_RS00245	COG4886	Leucine-rich repeat (LRR) protein
GXP71_RS00250	COG3795	YCII-related domain
GXP71_RS00255	COG4941	Belongs to the sigma-70 factor family
GXP71_RS00270	COG2226	methyltransferase
GXP71_RS00295	COG2814	Major facilitator Superfamily
GXP71_RS00305	COG1063	alcohol dehydrogenase
GXP71_RS00315	COG1140	nitrate reductase beta subunit
GXP71_RS00345	COG1970	mechanosensitive ion channel activity
GXP71_RS00455	COG0739	heme binding
GXP71_RS00545	COG1595	DNA-templated transcription, initiation
GXP71_RS00550	COG1302	Protein conserved in bacteria
GXP71_RS00605	COG1132	(ABC) transporter
GXP71_RS00615	COG1335	isochorismatase
GXP71_RS00620	COG2133	pyrroloquinoline quinone binding
GXP71_RS00635	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GXP71_RS00640	COG0084	hydrolase, TatD family'
GXP71_RS00645	COG3583	domain protein
GXP71_RS00645	COG3584	3D domain protein
GXP71_RS00650	COG3583	domain protein
GXP71_RS00655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GXP71_RS00660	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GXP71_RS00665	COG0488	(ABC) transporter
GXP71_RS00700	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GXP71_RS00730	COG2807	transmembrane transport
GXP71_RS00735	COG1846	Transcriptional regulator
GXP71_RS00750	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GXP71_RS00760	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GXP71_RS00765	COG0193	aminoacyl-tRNA hydrolase activity
GXP71_RS00795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GXP71_RS00840	COG0438	transferase activity, transferring glycosyl groups
GXP71_RS00850	COG0489	protein tyrosine kinase activity
GXP71_RS00885	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GXP71_RS00890	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GXP71_RS00900	COG0148	phosphopyruvate hydratase activity
GXP71_RS00935	COG1252	NADH dehydrogenase
GXP71_RS00960	COG3268	Saccharopine dehydrogenase
GXP71_RS01005	COG1131	(ABC) transporter
GXP71_RS01020	COG3458	cephalosporin-C deacetylase activity
GXP71_RS01025	COG0318	PFAM AMP-dependent synthetase and ligase
GXP71_RS01045	COG0277	FAD linked oxidase domain protein
GXP71_RS01065	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GXP71_RS01080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GXP71_RS01085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GXP71_RS01095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GXP71_RS01105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GXP71_RS01115	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GXP71_RS01125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GXP71_RS01135	COG0577	efflux transmembrane transporter activity
GXP71_RS01135	COG1136	(ABC) transporter
GXP71_RS01170	COG0114	fumarate hydratase activity
GXP71_RS01180	COG0288	reversible hydration of carbon dioxide
GXP71_RS01210	COG1722	exodeoxyribonuclease VII activity
GXP71_RS01215	COG1570	exodeoxyribonuclease VII activity
GXP71_RS01220	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GXP71_RS01225	COG1322	Protein conserved in bacteria
GXP71_RS01230	COG1131	(ABC) transporter
GXP71_RS01300	COG1028	Short-chain dehydrogenase reductase Sdr
GXP71_RS01335	COG0747	negative chemotaxis
GXP71_RS01345	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GXP71_RS01395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GXP71_RS01400	COG1611	Belongs to the LOG family
GXP71_RS01405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GXP71_RS01420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GXP71_RS01425	COG4122	O-methyltransferase activity
GXP71_RS01445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GXP71_RS01470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GXP71_RS01475	COG1053	succinate dehydrogenase
GXP71_RS01485	COG2009	succinate dehydrogenase
GXP71_RS01490	COG0662	Cupin 2, conserved barrel domain protein
GXP71_RS01490	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GXP71_RS01495	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GXP71_RS01495	COG1473	amidohydrolase
GXP71_RS01500	COG1744	ABC transporter substrate-binding protein PnrA-like
GXP71_RS01550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GXP71_RS01560	COG4733	cellulase activity
GXP71_RS01560	COG5297	Belongs to the glycosyl hydrolase family 6
GXP71_RS01565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GXP71_RS01585	COG2837	iron assimilation
GXP71_RS01595	COG0672	)-iron permease
GXP71_RS01605	COG4770	biotin carboxylase activity
GXP71_RS01610	COG0424	maF-like protein
GXP71_RS01635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GXP71_RS01640	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GXP71_RS01640	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GXP71_RS01655	COG2814	Major facilitator Superfamily
GXP71_RS01675	COG1454	alcohol dehydrogenase
GXP71_RS01675	COG1012	belongs to the aldehyde dehydrogenase family
GXP71_RS01695	COG1396	sequence-specific DNA binding
GXP71_RS01705	COG0025	NhaP-type Na H and K H
GXP71_RS01735	COG0745	RESPONSE REGULATOR receiver
GXP71_RS01740	COG2205	protein histidine kinase activity
GXP71_RS01760	COG2132	Multicopper oxidase
GXP71_RS01760	COG2132	Multicopper oxidase
GXP71_RS01770	COG2186	Transcriptional regulator
GXP71_RS01775	COG0018	arginyl-trna synthetase
GXP71_RS01780	COG0019	diaminopimelate decarboxylase activity
GXP71_RS01785	COG0460	homoserine dehydrogenase
GXP71_RS01790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GXP71_RS01795	COG0083	homoserine kinase activity
GXP71_RS01825	COG0254	rRNA binding
GXP71_RS01830	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GXP71_RS01845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GXP71_RS01855	COG0356	it plays a direct role in the translocation of protons across the membrane
GXP71_RS01860	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GXP71_RS01865	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GXP71_RS01870	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GXP71_RS01875	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GXP71_RS01880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GXP71_RS01885	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GXP71_RS01890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GXP71_RS01900	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
GXP71_RS01930	COG1472	Belongs to the glycosyl hydrolase 3 family
GXP71_RS01940	COG4209	transmembrane transport
GXP71_RS01945	COG0395	ABC-type sugar transport system, permease component
GXP71_RS01955	COG1609	Transcriptional regulator
GXP71_RS01965	COG1501	Belongs to the glycosyl hydrolase 31 family
GXP71_RS01980	COG0561	phosphatase activity
GXP71_RS01990	COG2267	carboxylic ester hydrolase activity
GXP71_RS02040	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GXP71_RS02065	COG0395	ABC-type sugar transport system, permease component
GXP71_RS02070	COG1175	transmembrane transport
GXP71_RS02085	COG3281	Trehalose synthase
GXP71_RS02095	COG0366	Alpha amylase catalytic
GXP71_RS02115	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GXP71_RS02120	COG3642	lipopolysaccharide core region biosynthetic process
GXP71_RS02130	COG0482	sulfurtransferase activity
GXP71_RS02155	COG1940	carbohydrate kinase activity
GXP71_RS02160	COG1129	ABC transporter
GXP71_RS02165	COG1172	Belongs to the binding-protein-dependent transport system permease family
GXP71_RS02170	COG1879	ABC-type sugar transport system periplasmic component
GXP71_RS02175	COG0673	inositol 2-dehydrogenase activity
GXP71_RS02195	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GXP71_RS02200	COG0154	amidase activity
GXP71_RS02205	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GXP71_RS02240	COG3104	oligopeptide transport
GXP71_RS02245	COG2154	pterin-4-alpha-carbinolamine dehydratase
GXP71_RS02255	COG3142	Participates in the control of copper homeostasis
GXP71_RS02260	COG1609	Transcriptional regulator
GXP71_RS02270	COG1175	transmembrane transport
GXP71_RS02275	COG0395	ABC-type sugar transport system, permease component
GXP71_RS02280	COG1472	Belongs to the glycosyl hydrolase 3 family
GXP71_RS02285	COG0129	dihydroxy-acid dehydratase activity
GXP71_RS02315	COG0129	dihydroxy-acid dehydratase activity
GXP71_RS02330	COG1940	carbohydrate kinase activity
GXP71_RS02330	COG1846	Transcriptional regulator
GXP71_RS02345	COG1175	transmembrane transport
GXP71_RS02350	COG0395	ABC-type sugar transport system, permease component
GXP71_RS02355	COG0366	Alpha amylase catalytic
GXP71_RS02365	COG1131	(ABC) transporter
GXP71_RS02375	COG1131	(ABC) transporter
GXP71_RS02390	COG4585	Histidine kinase
GXP71_RS02395	COG2197	response regulator
GXP71_RS02425	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GXP71_RS02435	COG0473	3-isopropylmalate dehydrogenase activity
GXP71_RS02440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GXP71_RS02450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GXP71_RS02460	COG0095	Lipoate-protein ligase
GXP71_RS02470	COG2149	membrane
GXP71_RS02480	COG1396	sequence-specific DNA binding
GXP71_RS02480	COG3800	Transcriptional regulator
GXP71_RS02500	COG3304	Inner membrane component domain
GXP71_RS02565	COG1215	transferase activity, transferring glycosyl groups
GXP71_RS02585	COG0179	Fumarylacetoacetate (FAA) hydrolase
GXP71_RS02600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GXP71_RS02620	COG0483	inositol monophosphate 1-phosphatase activity
GXP71_RS02625	COG1162	GTPase activity
GXP71_RS02630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GXP71_RS02640	COG1528	Iron-storage protein
GXP71_RS02645	COG1595	DNA-templated transcription, initiation
GXP71_RS02685	COG0508	dehydrogenase complex catalyzes the overall conversion of
GXP71_RS02685	COG0567	Dehydrogenase, E1 component
GXP71_RS02695	COG1131	(ABC) transporter
GXP71_RS02700	COG2205	protein histidine kinase activity
GXP71_RS02705	COG0745	RESPONSE REGULATOR receiver
GXP71_RS02710	COG1253	flavin adenine dinucleotide binding
GXP71_RS02730	COG2017	converts alpha-aldose to the beta-anomer
GXP71_RS02735	COG1028	Short-chain dehydrogenase reductase Sdr
GXP71_RS02780	COG0318	PFAM AMP-dependent synthetase and ligase
GXP71_RS02810	COG1960	acyl-CoA dehydrogenase activity
GXP71_RS02815	COG0183	Belongs to the thiolase family
GXP71_RS02885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GXP71_RS02895	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GXP71_RS02910	COG4214	carbohydrate transport
GXP71_RS02925	COG2884	Cell division ATP-binding protein ftsE
GXP71_RS02930	COG2177	Part of the ABC transporter FtsEX involved in
GXP71_RS02940	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GXP71_RS02960	COG1793	dna ligase
GXP71_RS03025	COG4106	trans-aconitate 2-methyltransferase activity
GXP71_RS03060	COG0028	Belongs to the TPP enzyme family
GXP71_RS03065	COG1309	transcriptional regulator
GXP71_RS03100	COG0183	Belongs to the thiolase family
GXP71_RS03115	COG0508	dehydrogenase complex catalyzes the overall conversion of
GXP71_RS03120	COG0022	dehydrogenase e1 component
GXP71_RS03135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GXP71_RS03145	COG1960	acyl-CoA dehydrogenase activity
GXP71_RS03175	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GXP71_RS03195	COG1785	Belongs to the alkaline phosphatase family
GXP71_RS03235	COG1301	dicarboxylic acid transport
GXP71_RS03245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GXP71_RS03250	COG1074	ATP-dependent DNA helicase activity
GXP71_RS03255	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GXP71_RS03320	COG0584	glycerophosphoryl diester phosphodiesterase
GXP71_RS03340	COG2319	Wd-40 repeat
GXP71_RS03340	COG4249	Peptidase C14 caspase catalytic subunit p20
GXP71_RS03350	COG1254	Belongs to the acylphosphatase family
GXP71_RS03355	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GXP71_RS03360	COG1854	S-ribosylhomocysteine lyase activity
GXP71_RS03380	COG0745	RESPONSE REGULATOR receiver
GXP71_RS03385	COG2205	protein histidine kinase activity
GXP71_RS03390	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GXP71_RS03395	COG1357	PFAM Pentapeptide repeats (8 copies)
GXP71_RS03410	COG2197	response regulator
GXP71_RS03425	COG0346	lactoylglutathione lyase activity
GXP71_RS03475	COG1140	nitrate reductase beta subunit
GXP71_RS03505	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GXP71_RS03510	COG5297	Belongs to the glycosyl hydrolase family 6
GXP71_RS03515	COG0166	Belongs to the GPI family
GXP71_RS03540	COG1940	carbohydrate kinase activity
GXP71_RS03540	COG1846	Transcriptional regulator
GXP71_RS03545	COG2182	Extracellular solute-binding protein
GXP71_RS03550	COG1175	transmembrane transport
GXP71_RS03555	COG0395	ABC-type sugar transport system, permease component
GXP71_RS03560	COG1940	carbohydrate kinase activity
GXP71_RS03565	COG0363	glucosamine-6-phosphate deaminase activity
GXP71_RS03585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GXP71_RS03595	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GXP71_RS03600	COG1234	tRNA 3'-trailer cleavage
GXP71_RS03610	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GXP71_RS03615	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GXP71_RS03620	COG0488	(ABC) transporter
GXP71_RS03630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GXP71_RS03650	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GXP71_RS03670	COG0076	glutamate decarboxylase activity
GXP71_RS03685	COG1174	glycine betaine transport
GXP71_RS03690	COG1174	glycine betaine transport
GXP71_RS03710	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GXP71_RS03730	COG1215	transferase activity, transferring glycosyl groups
GXP71_RS03735	COG1366	Belongs to the anti-sigma-factor antagonist family
GXP71_RS03760	COG0629	single-stranded DNA binding
GXP71_RS03785	COG1215	transferase activity, transferring glycosyl groups
GXP71_RS03815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GXP71_RS03820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GXP71_RS03825	COG0668	transmembrane transport
GXP71_RS03830	COG1505	serine-type exopeptidase activity
GXP71_RS03850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GXP71_RS03860	COG3590	peptidase
GXP71_RS03865	COG0698	ribose 5-phosphate isomerase
GXP71_RS03870	COG4552	Acetyltransferase involved in intracellular survival and related
GXP71_RS03875	COG2208	phosphoserine phosphatase activity
GXP71_RS03875	COG2770	Histidine kinase
GXP71_RS03885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS03900	COG1045	serine acetyltransferase
GXP71_RS03925	COG3265	gluconokinase activity
GXP71_RS03935	COG0517	IMP dehydrogenase activity
GXP71_RS03975	COG0544	peptidyl-prolyl cis-trans isomerase activity
GXP71_RS03980	COG0740	serine-type endopeptidase activity
GXP71_RS03985	COG0740	serine-type endopeptidase activity
GXP71_RS03990	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GXP71_RS04005	COG0287	Prephenate dehydrogenase
GXP71_RS04005	COG1605	Chorismate mutase
GXP71_RS04015	COG1022	Amp-dependent synthetase and ligase
GXP71_RS04020	COG0525	valine-tRNA ligase activity
GXP71_RS04025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS04030	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GXP71_RS04030	COG0778	Nitroreductase
GXP71_RS04070	COG1920	GTP binding
GXP71_RS04075	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GXP71_RS04080	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GXP71_RS04085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GXP71_RS04095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GXP71_RS04105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GXP71_RS04115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GXP71_RS04130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GXP71_RS04135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GXP71_RS04160	COG1132	(ABC) transporter
GXP71_RS04170	COG2197	response regulator
GXP71_RS04185	COG0789	Transcriptional regulator
GXP71_RS04195	COG5297	Belongs to the glycosyl hydrolase family 6
GXP71_RS04195	COG3250	beta-galactosidase activity
GXP71_RS04200	COG3507	Belongs to the glycosyl hydrolase 43 family
GXP71_RS04205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GXP71_RS04210	COG0285	dihydrofolate synthase activity
GXP71_RS04215	COG2376	Dihydroxyacetone kinase
GXP71_RS04220	COG1461	Dihydroxyacetone kinase
GXP71_RS04245	COG0105	UTP biosynthetic process
GXP71_RS04250	COG1196	nuclear chromosome segregation
GXP71_RS04275	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GXP71_RS04290	COG0228	four-way junction DNA binding
GXP71_RS04295	COG1837	Belongs to the UPF0109 family
GXP71_RS04300	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GXP71_RS04305	COG0336	Belongs to the RNA methyltransferase TrmD family
GXP71_RS04310	COG0335	large ribosomal subunit rRNA binding
GXP71_RS04320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GXP71_RS04330	COG0792	nuclease activity
GXP71_RS04345	COG1191	sigma factor activity
GXP71_RS04355	COG0052	Belongs to the universal ribosomal protein uS2 family
GXP71_RS04360	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GXP71_RS04370	COG0233	cytoplasmic translational termination
GXP71_RS04375	COG0575	Belongs to the CDS family
GXP71_RS04380	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GXP71_RS04390	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GXP71_RS04400	COG0750	zinc metalloprotease
GXP71_RS04405	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GXP71_RS04415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GXP71_RS04420	COG0442	prolyl-tRNA aminoacylation
GXP71_RS04430	COG0779	Required for maturation of 30S ribosomal subunits
GXP71_RS04445	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GXP71_RS04450	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GXP71_RS04465	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GXP71_RS04470	COG5297	Belongs to the glycosyl hydrolase family 6
GXP71_RS04470	COG3250	beta-galactosidase activity
GXP71_RS04480	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GXP71_RS04485	COG1185	polyribonucleotide nucleotidyltransferase activity
GXP71_RS04490	COG0612	Peptidase, M16
GXP71_RS04500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GXP71_RS04535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GXP71_RS04540	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GXP71_RS04545	COG0697	spore germination
GXP71_RS04550	COG4977	sequence-specific DNA binding
GXP71_RS04575	COG1674	ftsk spoiiie
GXP71_RS04595	COG1546	Belongs to the CinA family
GXP71_RS04595	COG1058	Belongs to the CinA family
GXP71_RS04600	COG1396	sequence-specific DNA binding
GXP71_RS04605	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GXP71_RS04610	COG1201	RNA secondary structure unwinding
GXP71_RS04630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GXP71_RS04635	COG2137	regulation of response to DNA damage stimulus
GXP71_RS04645	COG1418	mRNA catabolic process
GXP71_RS04650	COG0765	amino acid transport
GXP71_RS04655	COG0765	amino acid transport
GXP71_RS04660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GXP71_RS04665	COG1126	abc transporter atp-binding protein
GXP71_RS04670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GXP71_RS04690	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GXP71_RS04695	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GXP71_RS04710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GXP71_RS04730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GXP71_RS04745	COG1506	peptidase
GXP71_RS04745	COG0823	Involved in the tonB-independent uptake of proteins
GXP71_RS04745	COG4946	Tricorn protease homolog
GXP71_RS04750	COG0667	Aldo Keto reductase
GXP71_RS04760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GXP71_RS04775	COG4251	negative regulation of phosphorylation
GXP71_RS04780	COG0784	Response regulator, receiver
GXP71_RS04790	COG1278	Cold shock
GXP71_RS04805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GXP71_RS04825	COG0714	Associated with various cellular activities
GXP71_RS04830	COG2001	Belongs to the MraZ family
GXP71_RS04835	COG0275	rRNA processing
GXP71_RS04845	COG0768	penicillin binding
GXP71_RS04850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GXP71_RS04860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GXP71_RS04865	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GXP71_RS04875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GXP71_RS04880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GXP71_RS04885	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GXP71_RS04890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GXP71_RS04900	COG1799	cell septum assembly
GXP71_RS04910	COG3599	regulation of cell shape
GXP71_RS04920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GXP71_RS04930	COG0587	DNA-directed DNA polymerase activity
GXP71_RS04950	COG2501	S4 domain
GXP71_RS04955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GXP71_RS04960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GXP71_RS04965	COG0131	Imidazoleglycerol-phosphate dehydratase
GXP71_RS04975	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GXP71_RS04980	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GXP71_RS05025	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GXP71_RS05030	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GXP71_RS05035	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GXP71_RS05040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GXP71_RS05050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GXP71_RS05070	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GXP71_RS05075	COG0352	thiamine-phosphate diphosphorylase activity
GXP71_RS05080	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GXP71_RS05080	COG0352	thiamine-phosphate diphosphorylase activity
GXP71_RS05080	COG0351	phosphomethylpyrimidine kinase
GXP71_RS05085	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GXP71_RS05090	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GXP71_RS05095	COG0604	alcohol dehydrogenase
GXP71_RS05100	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GXP71_RS05105	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GXP71_RS05115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GXP71_RS05125	COG1438	arginine binding
GXP71_RS05130	COG0137	argininosuccinate synthase activity
GXP71_RS05135	COG0165	Argininosuccinate lyase
GXP71_RS05145	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GXP71_RS05145	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GXP71_RS05150	COG2094	Belongs to the DNA glycosylase MPG family
GXP71_RS05155	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GXP71_RS05180	COG0647	UMP catabolic process
GXP71_RS05190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GXP71_RS05195	COG0497	DNA recombination
GXP71_RS05220	COG0504	CTP synthase activity
GXP71_RS05225	COG0494	nUDIX hydrolase
GXP71_RS05265	COG1131	(ABC) transporter
GXP71_RS05280	COG0719	Fe-S assembly protein
GXP71_RS05290	COG0396	ATPase activity
GXP71_RS05300	COG0822	iron-sulfur transferase activity
GXP71_RS05305	COG2151	metal-sulfur cluster biosynthetic enzyme
GXP71_RS05320	COG3250	beta-galactosidase activity
GXP71_RS05320	COG5297	Belongs to the glycosyl hydrolase family 6
GXP71_RS05335	COG1122	ATPase activity
GXP71_RS05340	COG1268	BioY protein
GXP71_RS05345	COG0488	(ABC) transporter
GXP71_RS05395	COG0297	glycogen (starch) synthase activity
GXP71_RS05405	COG1119	ATPase activity
GXP71_RS05430	COG1028	Short-chain dehydrogenase reductase Sdr
GXP71_RS05445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GXP71_RS05475	COG1881	PFAM PEBP family protein
GXP71_RS05500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GXP71_RS05525	COG3507	Belongs to the glycosyl hydrolase 43 family
GXP71_RS05535	COG1609	Transcriptional regulator
GXP71_RS05545	COG4209	transmembrane transport
GXP71_RS05550	COG0395	ABC-type sugar transport system, permease component
GXP71_RS05570	COG1271	oxidase subunit
GXP71_RS05580	COG3387	PFAM Glycoside hydrolase 15-related
GXP71_RS05585	COG1252	NADH dehydrogenase
GXP71_RS05605	COG2072	flavoprotein involved in K transport
GXP71_RS05625	COG2755	lipolytic protein G-D-S-L family
GXP71_RS05675	COG0577	efflux transmembrane transporter activity
GXP71_RS05675	COG1136	(ABC) transporter
GXP71_RS05680	COG1136	(ABC) transporter
GXP71_RS05685	COG0531	amino acid
GXP71_RS05700	COG4585	Histidine kinase
GXP71_RS05705	COG2197	response regulator
GXP71_RS05710	COG1793	dna ligase
GXP71_RS05730	COG0686	Belongs to the AlaDH PNT family
GXP71_RS05735	COG1090	epimerase
GXP71_RS05740	COG0339	signal peptide processing
GXP71_RS05750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GXP71_RS05765	COG0667	Aldo Keto reductase
GXP71_RS05780	COG0215	cysteine-tRNA ligase activity
GXP71_RS05800	COG0517	IMP dehydrogenase activity
GXP71_RS05800	COG1994	Peptidase M50
GXP71_RS05810	COG1222	aaa ATPase
GXP71_RS05815	COG4122	O-methyltransferase activity
GXP71_RS05825	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GXP71_RS05830	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GXP71_RS05835	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GXP71_RS05845	COG0107	imidazoleglycerol-phosphate synthase activity
GXP71_RS05855	COG1132	(ABC) transporter
GXP71_RS05860	COG1132	(ABC) transporter
GXP71_RS05900	COG0134	indole-3-glycerol-phosphate synthase activity
GXP71_RS05905	COG0133	tryptophan synthase activity
GXP71_RS05910	COG0159	tryptophan synthase activity
GXP71_RS05915	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GXP71_RS05920	COG0070	glutamate synthase
GXP71_RS05920	COG0069	glutamate synthase activity
GXP71_RS05920	COG0067	glutamate synthase
GXP71_RS05935	COG1234	tRNA 3'-trailer cleavage
GXP71_RS05950	COG2267	carboxylic ester hydrolase activity
GXP71_RS05955	COG2354	Protein conserved in bacteria
GXP71_RS06005	COG3971	2-oxopent-4-enoate hydratase activity
GXP71_RS06020	COG1802	Transcriptional regulator
GXP71_RS06025	COG0179	Fumarylacetoacetate (FAA) hydrolase
GXP71_RS06030	COG0028	Belongs to the TPP enzyme family
GXP71_RS06100	COG2050	protein possibly involved in aromatic compounds catabolism
GXP71_RS06115	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GXP71_RS06120	COG2226	methyltransferase
GXP71_RS06125	COG0747	negative chemotaxis
GXP71_RS06145	COG0205	6-phosphofructokinase activity
GXP71_RS06150	COG0539	negative regulation of cytoplasmic translation
GXP71_RS06155	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GXP71_RS06155	COG0237	dephospho-CoA kinase activity
GXP71_RS06160	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GXP71_RS06165	COG0556	nucleotide-excision repair
GXP71_RS06210	COG1660	Displays ATPase and GTPase activities
GXP71_RS06220	COG1481	regulation of sporulation
GXP71_RS06225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GXP71_RS06230	COG0126	phosphoglycerate kinase activity
GXP71_RS06235	COG0149	triose-phosphate isomerase activity
GXP71_RS06240	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GXP71_RS06250	COG0363	glucosamine-6-phosphate deaminase activity
GXP71_RS06265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GXP71_RS06275	COG0109	protoheme IX farnesyltransferase activity
GXP71_RS06295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GXP71_RS06300	COG1187	pseudouridine synthase activity
GXP71_RS06310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GXP71_RS06320	COG1160	GTP binding
GXP71_RS06355	COG1595	DNA-templated transcription, initiation
GXP71_RS06385	COG0577	efflux transmembrane transporter activity
GXP71_RS06385	COG1136	(ABC) transporter
GXP71_RS06390	COG1136	(ABC) transporter
GXP71_RS06400	COG0300	oxidoreductase activity
GXP71_RS06410	COG3795	YCII-related domain
GXP71_RS06435	COG0442	prolyl-tRNA aminoacylation
GXP71_RS06450	COG2169	Transcriptional regulator
GXP71_RS06450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GXP71_RS06465	COG0579	oxidoreductase
GXP71_RS06485	COG0783	Belongs to the Dps family
GXP71_RS06490	COG3285	dna ligase
GXP71_RS06490	COG1793	dna ligase
GXP71_RS06500	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GXP71_RS06505	COG1796	DNA polymerase
GXP71_RS06505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GXP71_RS06510	COG0776	regulation of translation
GXP71_RS06535	COG5297	Belongs to the glycosyl hydrolase family 6
GXP71_RS06540	COG1609	Transcriptional regulator
GXP71_RS06545	COG1609	Transcriptional regulator
GXP71_RS06555	COG1832	CoA-binding protein
GXP71_RS06600	COG1192	Involved in chromosome partitioning
GXP71_RS06605	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GXP71_RS06620	COG4702	Belongs to the UPF0303 family
GXP71_RS06630	COG0667	Aldo Keto reductase
GXP71_RS06640	COG1216	Glycosyl transferase, family 2
GXP71_RS06650	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GXP71_RS06660	COG1597	lipid kinase activity
GXP71_RS06665	COG0805	protein transport
GXP71_RS06670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GXP71_RS06700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GXP71_RS06705	COG0140	phosphoribosyl-ATP diphosphatase activity
GXP71_RS06715	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GXP71_RS06720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GXP71_RS06720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GXP71_RS06735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GXP71_RS06745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GXP71_RS06750	COG1011	Hydrolase
GXP71_RS06760	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GXP71_RS06770	COG1758	RNA polymerase activity
GXP71_RS06775	COG0194	GDP metabolic process
GXP71_RS06785	COG0284	orotidine-5'-phosphate decarboxylase activity
GXP71_RS06790	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GXP71_RS06795	COG0505	Belongs to the CarA family
GXP71_RS06805	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GXP71_RS06810	COG0540	Belongs to the ATCase OTCase family
GXP71_RS06815	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GXP71_RS06820	COG0076	glutamate decarboxylase activity
GXP71_RS06850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GXP71_RS06855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GXP71_RS06870	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GXP71_RS06875	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GXP71_RS06880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GXP71_RS06895	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GXP71_RS06915	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GXP71_RS06955	COG1459	type II secretion system
GXP71_RS06965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GXP71_RS06970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GXP71_RS06975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GXP71_RS06980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GXP71_RS06985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GXP71_RS07000	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GXP71_RS07010	COG2409	Drug exporters of the RND superfamily
GXP71_RS07015	COG0456	acetyltransferase
GXP71_RS07020	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GXP71_RS07035	COG0124	histidyl-tRNA synthetase
GXP71_RS07045	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GXP71_RS07050	COG1196	nuclear chromosome segregation
GXP71_RS07055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GXP71_RS07060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GXP71_RS07065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GXP71_RS07070	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GXP71_RS07080	COG2255	four-way junction helicase activity
GXP71_RS07085	COG0632	four-way junction helicase activity
GXP71_RS07090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GXP71_RS07095	COG0217	transcriptional regulatory protein
GXP71_RS07100	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GXP71_RS07105	COG0436	Aminotransferase
GXP71_RS07110	COG1051	belongs to the nudix hydrolase family
GXP71_RS07115	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GXP71_RS07125	COG0438	transferase activity, transferring glycosyl groups
GXP71_RS07130	COG1560	Kdo2-lipid A biosynthetic process
GXP71_RS07135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GXP71_RS07145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GXP71_RS07190	COG1063	alcohol dehydrogenase
GXP71_RS07200	COG0739	heme binding
GXP71_RS07215	COG0659	secondary active sulfate transmembrane transporter activity
GXP71_RS07225	COG0737	Belongs to the 5'-nucleotidase family
GXP71_RS07285	COG3546	catalase activity
GXP71_RS07290	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GXP71_RS07340	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GXP71_RS07410	COG0175	sulfate reduction
GXP71_RS07425	COG1648	precorrin-2 dehydrogenase activity
GXP71_RS07425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GXP71_RS07445	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GXP71_RS07455	COG2197	response regulator
GXP71_RS07460	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GXP71_RS07465	COG0183	Belongs to the thiolase family
GXP71_RS07495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GXP71_RS07500	COG1882	Formate acetyltransferase
GXP71_RS07505	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GXP71_RS07515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GXP71_RS07515	COG0519	Catalyzes the synthesis of GMP from XMP
GXP71_RS07520	COG0494	nUDIX hydrolase
GXP71_RS07550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GXP71_RS07560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GXP71_RS07565	COG0531	amino acid
GXP71_RS07570	COG0569	domain protein
GXP71_RS07595	COG0756	dUTP diphosphatase activity
GXP71_RS07620	COG1435	thymidine kinase activity
GXP71_RS07625	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GXP71_RS07640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GXP71_RS07650	COG0456	acetyltransferase
GXP71_RS07655	COG0187	DNA topoisomerase II activity
GXP71_RS07680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GXP71_RS07685	COG0589	response to stress
GXP71_RS07700	COG0142	geranyltranstransferase activity
GXP71_RS07710	COG3942	CHAP domain
GXP71_RS07710	COG1388	LysM domain
GXP71_RS07715	COG0515	serine threonine protein kinase
GXP71_RS07715	COG2815	serine threonine protein kinase
GXP71_RS07720	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GXP71_RS07740	COG1940	carbohydrate kinase activity
GXP71_RS07775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GXP71_RS07785	COG1845	cytochrome c oxidase, subunit III
GXP71_RS07790	COG2010	Cytochrome c
GXP71_RS07795	COG0723	plastoquinol--plastocyanin reductase activity
GXP71_RS07800	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GXP71_RS07825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GXP71_RS07830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GXP71_RS07835	COG1104	cysteine desulfurase activity
GXP71_RS07840	COG0425	Belongs to the sulfur carrier protein TusA family
GXP71_RS07855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GXP71_RS07880	COG0667	Aldo Keto reductase
GXP71_RS07885	COG2364	Membrane
GXP71_RS07895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GXP71_RS07905	COG0167	dihydroorotate dehydrogenase activity
GXP71_RS07920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GXP71_RS07930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GXP71_RS07935	COG0508	dehydrogenase complex catalyzes the overall conversion of
GXP71_RS07940	COG1090	epimerase
GXP71_RS07950	COG0673	inositol 2-dehydrogenase activity
GXP71_RS07955	COG2409	Drug exporters of the RND superfamily
GXP71_RS07965	COG0321	lipoyl(octanoyl) transferase activity
GXP71_RS07975	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GXP71_RS07995	COG0174	glutamine synthetase
GXP71_RS08020	COG3507	Belongs to the glycosyl hydrolase 43 family
GXP71_RS08060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS08080	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GXP71_RS08085	COG0174	glutamine synthetase
GXP71_RS08090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GXP71_RS08090	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GXP71_RS08095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GXP71_RS08190	COG3022	response to hydroperoxide
GXP71_RS08210	COG3323	Protein of unknown function (DUF1653)
GXP71_RS08210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GXP71_RS08240	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GXP71_RS08260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GXP71_RS08265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GXP71_RS08275	COG1017	nitric oxide dioxygenase activity
GXP71_RS08275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GXP71_RS08280	COG1477	protein flavinylation
GXP71_RS08305	COG1511	domain protein
GXP71_RS08310	COG1309	transcriptional regulator
GXP71_RS08360	COG1028	Short-chain dehydrogenase reductase Sdr
GXP71_RS08370	COG2197	response regulator
GXP71_RS08400	COG0515	serine threonine protein kinase
GXP71_RS08405	COG2860	membrane
GXP71_RS08425	COG1305	Transglutaminase-like
GXP71_RS08435	COG0358	DNA primase activity
GXP71_RS08455	COG3833	ABC-type maltose transport systems, permease component
GXP71_RS08460	COG1175	transmembrane transport
GXP71_RS08470	COG1609	Transcriptional regulator
GXP71_RS08475	COG0366	Alpha amylase catalytic
GXP71_RS08485	COG0784	Response regulator, receiver
GXP71_RS08485	COG2205	protein histidine kinase activity
GXP71_RS08495	COG2172	sigma factor antagonist activity
GXP71_RS08500	COG1366	Belongs to the anti-sigma-factor antagonist family
GXP71_RS08505	COG1366	Belongs to the anti-sigma-factor antagonist family
GXP71_RS08515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GXP71_RS08530	COG2197	response regulator
GXP71_RS08535	COG4585	Histidine kinase
GXP71_RS08540	COG0842	Transport permease protein
GXP71_RS08545	COG1131	(ABC) transporter
GXP71_RS08555	COG0423	glycine-tRNA ligase activity
GXP71_RS08560	COG3443	Belongs to the bacterial solute-binding protein 9 family
GXP71_RS08560	COG0803	Belongs to the bacterial solute-binding protein 9 family
GXP71_RS08565	COG1121	(ABC) transporter
GXP71_RS08585	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GXP71_RS08590	COG1381	Involved in DNA repair and RecF pathway recombination
GXP71_RS08595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GXP71_RS08625	COG0714	Associated with various cellular activities
GXP71_RS08645	COG0631	protein serine/threonine phosphatase activity
GXP71_RS08655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GXP71_RS08665	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GXP71_RS08675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GXP71_RS08675	COG0574	Belongs to the PEP-utilizing enzyme family
GXP71_RS08690	COG0484	heat shock protein binding
GXP71_RS08695	COG1420	regulation of RNA biosynthetic process
GXP71_RS08730	COG0481	GTPase activity
GXP71_RS08740	COG1305	Transglutaminase-like
GXP71_RS08760	COG0268	Binds directly to 16S ribosomal RNA
GXP71_RS08780	COG2200	EAL domain
GXP71_RS08780	COG2199	diguanylate cyclase activity
GXP71_RS08800	COG1307	EDD domain protein, DegV family
GXP71_RS08805	COG0495	leucyl-tRNA aminoacylation
GXP71_RS08810	COG0433	COG0433 Predicted ATPase
GXP71_RS08815	COG2814	Major facilitator Superfamily
GXP71_RS08820	COG1321	iron dependent repressor
GXP71_RS08855	COG1122	ATPase activity
GXP71_RS08870	COG2514	catechol 2,3-dioxygenase activity
GXP71_RS08885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GXP71_RS08890	COG0543	2 iron, 2 sulfur cluster binding
GXP71_RS08890	COG0633	Ferredoxin
GXP71_RS08905	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GXP71_RS08920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GXP71_RS08945	COG1609	Transcriptional regulator
GXP71_RS08950	COG1621	beta-fructofuranosidase activity
GXP71_RS08955	COG1621	beta-fructofuranosidase activity
GXP71_RS08985	COG1904	glucuronate isomerase
GXP71_RS08990	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GXP71_RS09000	COG3250	beta-galactosidase activity
GXP71_RS09005	COG1609	Transcriptional regulator
GXP71_RS09010	COG0246	Mannitol dehydrogenase
GXP71_RS09015	COG4948	Mandelate Racemase Muconate Lactonizing
GXP71_RS09020	COG3265	gluconokinase activity
GXP71_RS09025	COG1940	carbohydrate kinase activity
GXP71_RS09030	COG0366	Alpha amylase catalytic
GXP71_RS09040	COG1175	transmembrane transport
GXP71_RS09045	COG0395	ABC-type sugar transport system, permease component
GXP71_RS09055	COG3706	GGDEF domain
GXP71_RS09060	COG2190	(PTS) system
GXP71_RS09065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GXP71_RS09065	COG1263	PTS System
GXP71_RS09065	COG2190	(PTS) system
GXP71_RS09070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GXP71_RS09075	COG2188	Transcriptional regulator
GXP71_RS09080	COG1263	PTS System
GXP71_RS09085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GXP71_RS09090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GXP71_RS09120	COG2197	response regulator
GXP71_RS09125	COG4585	Histidine kinase
GXP71_RS09135	COG0494	nUDIX hydrolase
GXP71_RS09150	COG0588	phosphoglycerate mutase activity
GXP71_RS09155	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GXP71_RS09165	COG0667	Aldo Keto reductase
GXP71_RS09170	COG0671	phosphoesterase, PA-phosphatase related
GXP71_RS09175	COG2326	polyphosphate kinase activity
GXP71_RS09195	COG0799	negative regulation of ribosome biogenesis
GXP71_RS09205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GXP71_RS09210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GXP71_RS09230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS09240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS09255	COG0747	negative chemotaxis
GXP71_RS09270	COG0601	transmembrane transport
GXP71_RS09275	COG0601	transmembrane transport
GXP71_RS09290	COG0747	negative chemotaxis
GXP71_RS09295	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GXP71_RS09300	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GXP71_RS09305	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GXP71_RS09310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GXP71_RS09315	COG1295	ribonuclease BN
GXP71_RS09320	COG1530	ribonuclease E activity
GXP71_RS09325	COG1271	oxidase subunit
GXP71_RS09335	COG4988	ABC transporter
GXP71_RS09340	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GXP71_RS09350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GXP71_RS09360	COG0531	amino acid
GXP71_RS09375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GXP71_RS09380	COG0571	ribonuclease III activity
GXP71_RS09385	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GXP71_RS09405	COG0742	ribosomal rna small subunit methyltransferase
GXP71_RS09415	COG4133	protoheme IX ABC transporter activity
GXP71_RS09425	COG1461	Dihydroxyacetone kinase
GXP71_RS09430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GXP71_RS09450	COG1181	Belongs to the D-alanine--D-alanine ligase family
GXP71_RS09460	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GXP71_RS09470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GXP71_RS09475	COG0066	3-isopropylmalate dehydratase activity
GXP71_RS09480	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GXP71_RS09485	COG1414	Transcriptional regulator
GXP71_RS09535	COG0653	protein targeting
GXP71_RS09545	COG3214	Protein conserved in bacteria
GXP71_RS09550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GXP71_RS09560	COG5401	PFAM Sporulation and spore germination
GXP71_RS09565	COG5000	phosphorelay sensor kinase activity
GXP71_RS09565	COG5002	protein histidine kinase activity
GXP71_RS09570	COG0745	RESPONSE REGULATOR receiver
GXP71_RS09590	COG0714	Associated with various cellular activities
GXP71_RS09615	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GXP71_RS09620	COG2835	tetraacyldisaccharide 4'-kinase activity
GXP71_RS09680	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GXP71_RS09705	COG1216	Glycosyl transferase, family 2
GXP71_RS09725	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GXP71_RS09735	COG0438	transferase activity, transferring glycosyl groups
GXP71_RS09745	COG0438	transferase activity, transferring glycosyl groups
GXP71_RS09745	COG1216	Glycosyl transferase, family 2
GXP71_RS09750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GXP71_RS09775	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GXP71_RS09780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GXP71_RS09800	COG1088	dTDP-glucose 4,6-dehydratase activity
GXP71_RS09805	COG1316	TRANSCRIPTIONal
GXP71_RS09810	COG1316	TRANSCRIPTIONal
GXP71_RS09820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GXP71_RS09835	COG1482	cell wall glycoprotein biosynthetic process
GXP71_RS09840	COG2205	protein histidine kinase activity
GXP71_RS09845	COG0745	RESPONSE REGULATOR receiver
GXP71_RS09850	COG4585	Histidine kinase
GXP71_RS09855	COG2197	response regulator
GXP71_RS09860	COG1136	(ABC) transporter
GXP71_RS09905	COG0395	ABC-type sugar transport system, permease component
GXP71_RS09915	COG1012	belongs to the aldehyde dehydrogenase family
GXP71_RS09925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GXP71_RS09930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS09950	COG0395	ABC-type sugar transport system, permease component
GXP71_RS09955	COG1175	transmembrane transport
GXP71_RS09960	COG1653	transport
GXP71_RS09965	COG0366	Alpha amylase catalytic
GXP71_RS09975	COG0515	serine threonine protein kinase
GXP71_RS10020	COG1648	precorrin-2 dehydrogenase activity
GXP71_RS10020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GXP71_RS10030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GXP71_RS10040	COG4152	abc transporter atp-binding protein
GXP71_RS10045	COG1668	transmembrane transport
GXP71_RS10050	COG0537	adenosine 5'-monophosphoramidase activity
GXP71_RS10055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GXP71_RS10060	COG0243	molybdopterin cofactor binding
GXP71_RS10065	COG2223	nitrite transmembrane transporter activity
GXP71_RS10085	COG3585	molybdate ion transport
GXP71_RS10090	COG2326	polyphosphate kinase activity
GXP71_RS10100	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GXP71_RS10105	COG0300	oxidoreductase activity
GXP71_RS10110	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GXP71_RS10110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GXP71_RS10200	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GXP71_RS10205	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GXP71_RS10230	COG0723	plastoquinol--plastocyanin reductase activity
GXP71_RS10245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GXP71_RS10255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GXP71_RS10280	COG1609	Transcriptional regulator
GXP71_RS10315	COG2011	ABC-type metal ion transport system permease component
GXP71_RS10320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GXP71_RS10355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS10360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS10380	COG1126	abc transporter atp-binding protein
GXP71_RS10400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS10405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS10420	COG3237	CsbD-like
GXP71_RS10435	COG0243	molybdopterin cofactor binding
GXP71_RS10445	COG0604	alcohol dehydrogenase
GXP71_RS10465	COG1028	Short-chain dehydrogenase reductase Sdr
GXP71_RS10475	COG1615	UPF0182 protein
GXP71_RS10485	COG0384	phenazine biosynthesis protein PhzF
GXP71_RS10490	COG3480	Lon protease (S16) C-terminal proteolytic domain
GXP71_RS10545	COG0210	DNA helicase
GXP71_RS10575	COG0513	Belongs to the DEAD box helicase family
GXP71_RS10580	COG2095	MarC family integral membrane protein
GXP71_RS10585	COG0613	PHP domain protein
GXP71_RS10590	COG0006	proline dipeptidase activity
GXP71_RS10600	COG2239	Acts as a magnesium transporter
GXP71_RS10615	COG1349	DNA-binding transcription factor activity
GXP71_RS10625	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GXP71_RS10635	COG0577	efflux transmembrane transporter activity
GXP71_RS10635	COG1136	(ABC) transporter
GXP71_RS10640	COG0577	efflux transmembrane transporter activity
GXP71_RS10670	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GXP71_RS10680	COG0346	lactoylglutathione lyase activity
GXP71_RS10695	COG1846	Transcriptional regulator
GXP71_RS10720	COG3509	depolymerase
GXP71_RS10740	COG1872	DUF167
GXP71_RS10745	COG0039	L-malate dehydrogenase activity
GXP71_RS10765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GXP71_RS10770	COG0138	bifunctional purine biosynthesis protein purh
GXP71_RS10795	COG0045	succinate-CoA ligase (ADP-forming) activity
GXP71_RS10810	COG0572	uridine kinase
GXP71_RS10820	COG0542	response to heat
GXP71_RS10835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GXP71_RS10855	COG2197	response regulator
GXP71_RS10885	COG0438	transferase activity, transferring glycosyl groups
GXP71_RS10895	COG0519	Catalyzes the synthesis of GMP from XMP
GXP71_RS10895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GXP71_RS10900	COG1132	(ABC) transporter
GXP71_RS10905	COG1132	(ABC) transporter
GXP71_RS10910	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GXP71_RS10925	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GXP71_RS10935	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GXP71_RS10955	COG1028	Short-chain dehydrogenase reductase Sdr
GXP71_RS10975	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GXP71_RS10980	COG1012	belongs to the aldehyde dehydrogenase family
GXP71_RS10985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GXP71_RS10990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GXP71_RS11005	COG1105	Belongs to the carbohydrate kinase PfkB family
GXP71_RS11010	COG1349	DNA-binding transcription factor activity
GXP71_RS11015	COG0516	GMP reductase activity
GXP71_RS11025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GXP71_RS11035	COG2197	response regulator
GXP71_RS11050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GXP71_RS11060	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GXP71_RS11080	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GXP71_RS11085	COG0778	Nitroreductase
GXP71_RS11090	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GXP71_RS11095	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GXP71_RS11100	COG0714	Associated with various cellular activities
GXP71_RS11125	COG0456	acetyltransferase
GXP71_RS11125	COG1214	PFAM Peptidase M22, glycoprotease
GXP71_RS11130	COG0802	atpase or kinase
GXP71_RS11135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GXP71_RS11140	COG1072	(Pantothenic acid kinase))
GXP71_RS11150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS11155	COG0736	holo-[acyl-carrier-protein] synthase activity
GXP71_RS11160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GXP71_RS11165	COG1072	(Pantothenic acid kinase))
GXP71_RS11180	COG0242	peptide deformylase activity
GXP71_RS11185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GXP71_RS11190	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GXP71_RS11195	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GXP71_RS11215	COG0488	(ABC) transporter
GXP71_RS11225	COG0101	tRNA pseudouridine synthase activity
GXP71_RS11240	COG0203	ribosomal protein L17
GXP71_RS11245	COG0202	RNA polymerase activity
GXP71_RS11250	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GXP71_RS11255	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GXP71_RS11260	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GXP71_RS11265	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GXP71_RS11280	COG0563	adenylate kinase activity
GXP71_RS11290	COG0200	Binds to the 23S rRNA
GXP71_RS11295	COG1841	ribosomal large subunit assembly
GXP71_RS11300	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GXP71_RS11305	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GXP71_RS11310	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GXP71_RS11315	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GXP71_RS11325	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GXP71_RS11330	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GXP71_RS11335	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GXP71_RS11340	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GXP71_RS11345	COG0255	Belongs to the universal ribosomal protein uL29 family
GXP71_RS11350	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GXP71_RS11355	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GXP71_RS11360	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GXP71_RS11365	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GXP71_RS11370	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GXP71_RS11375	COG0089	rRNA binding
GXP71_RS11380	COG0088	Forms part of the polypeptide exit tunnel
GXP71_RS11385	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GXP71_RS11390	COG0051	transcription antitermination factor activity, RNA binding
GXP71_RS11405	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GXP71_RS11410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GXP71_RS11415	COG0049	tRNA binding
GXP71_RS11420	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GXP71_RS11425	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GXP71_RS11430	COG0085	RNA polymerase activity
GXP71_RS11445	COG0222	ribosome binding
GXP71_RS11450	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GXP71_RS11480	COG0081	regulation of translation
GXP71_RS11485	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GXP71_RS11490	COG0250	Participates in transcription elongation, termination and antitermination
GXP71_RS11505	COG0436	Aminotransferase
GXP71_RS11510	COG5002	protein histidine kinase activity
GXP71_RS11515	COG0745	RESPONSE REGULATOR receiver
GXP71_RS11525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GXP71_RS11530	COG0738	Major facilitator superfamily
GXP71_RS11555	COG2030	dehydratase
GXP71_RS11560	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GXP71_RS11585	COG1666	GTP binding
GXP71_RS11595	COG0501	Belongs to the peptidase M48B family
GXP71_RS11605	COG0765	amino acid transport
GXP71_RS11640	COG1007	ATP synthesis coupled electron transport
GXP71_RS11650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GXP71_RS11655	COG0713	ATP synthesis coupled electron transport
GXP71_RS11665	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GXP71_RS11670	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GXP71_RS11675	COG1034	ATP synthesis coupled electron transport
GXP71_RS11680	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GXP71_RS11690	COG0649	NAD binding
GXP71_RS11695	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GXP71_RS11700	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GXP71_RS11715	COG2226	methyltransferase
GXP71_RS11720	COG1169	isochorismate synthase
GXP71_RS11730	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GXP71_RS11735	COG4948	Mandelate Racemase Muconate Lactonizing
GXP71_RS11750	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GXP71_RS11755	COG1470	cell adhesion involved in biofilm formation
GXP71_RS11760	COG1470	cell adhesion involved in biofilm formation
GXP71_RS11770	COG1575	Belongs to the MenA family. Type 1 subfamily
GXP71_RS11785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GXP71_RS11790	COG1333	cytochrome c biogenesis protein
GXP71_RS11795	COG0785	Cytochrome C biogenesis protein
GXP71_RS11805	COG0406	alpha-ribazole phosphatase activity
GXP71_RS11815	COG2353	YceI-like domain
GXP71_RS11820	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GXP71_RS11870	COG0395	ABC-type sugar transport system, permease component
GXP71_RS11875	COG3507	Belongs to the glycosyl hydrolase 43 family
GXP71_RS11900	COG1609	Transcriptional regulator
GXP71_RS11915	COG0123	including yeast histone deacetylase and acetoin utilization protein
GXP71_RS11920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GXP71_RS11925	COG0569	domain protein
GXP71_RS11940	COG1172	Belongs to the binding-protein-dependent transport system permease family
GXP71_RS11945	COG1172	Belongs to the binding-protein-dependent transport system permease family
GXP71_RS11955	COG1879	ABC-type sugar transport system periplasmic component
GXP71_RS11975	COG0395	ABC-type sugar transport system, permease component
GXP71_RS11985	COG1653	transport
GXP71_RS12015	COG2890	protein-(glutamine-N5) methyltransferase activity
GXP71_RS12055	COG2160	L-arabinose isomerase activity
GXP71_RS12070	COG1609	Transcriptional regulator
GXP71_RS12075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GXP71_RS12090	COG1136	(ABC) transporter
GXP71_RS12090	COG0577	efflux transmembrane transporter activity
GXP71_RS12095	COG1136	(ABC) transporter
GXP71_RS12100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GXP71_RS12110	COG2890	protein-(glutamine-N5) methyltransferase activity
GXP71_RS12115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GXP71_RS12130	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GXP71_RS12150	COG0596	Alpha beta hydrolase
GXP71_RS12160	COG1595	DNA-templated transcription, initiation
GXP71_RS12180	COG1595	DNA-templated transcription, initiation
GXP71_RS12190	COG1366	Belongs to the anti-sigma-factor antagonist family
GXP71_RS12205	COG1984	allophanate hydrolase subunit 2
GXP71_RS12215	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GXP71_RS12220	COG1205	dead DEAH box helicase
GXP71_RS12220	COG1111	helicase
GXP71_RS12275	COG1902	pentaerythritol trinitrate reductase activity
GXP71_RS12280	COG2116	formate transmembrane transporter activity
GXP71_RS12290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GXP71_RS12305	COG0456	acetyltransferase
GXP71_RS12310	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GXP71_RS12320	COG0306	phosphate transporter
GXP71_RS12335	COG0477	Major facilitator Superfamily
GXP71_RS12360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GXP71_RS12365	COG3300	MHYT domain
GXP71_RS12365	COG5001	Diguanylate cyclase
GXP71_RS12395	COG4566	intracellular signal transduction
GXP71_RS12395	COG0745	RESPONSE REGULATOR receiver
GXP71_RS12400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GXP71_RS12405	COG1181	Belongs to the D-alanine--D-alanine ligase family
GXP71_RS12420	COG0431	NADPH-dependent FMN reductase
GXP71_RS12425	COG1132	(ABC) transporter
GXP71_RS12430	COG1309	transcriptional regulator
GXP71_RS12505	COG0517	IMP dehydrogenase activity
GXP71_RS12525	COG0395	ABC-type sugar transport system, permease component
GXP71_RS12550	COG0745	RESPONSE REGULATOR receiver
GXP71_RS12570	COG3507	Belongs to the glycosyl hydrolase 43 family
GXP71_RS12590	COG3214	Protein conserved in bacteria
GXP71_RS12595	COG1742	UPF0060 membrane protein
GXP71_RS12605	COG2226	methyltransferase
GXP71_RS12610	COG1247	-acetyltransferase
GXP71_RS12645	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GXP71_RS12645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GXP71_RS12655	COG1335	isochorismatase
GXP71_RS12665	COG0640	Transcriptional regulator
GXP71_RS12670	COG2226	methyltransferase
GXP71_RS12680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GXP71_RS12715	COG2304	oxidoreductase activity
GXP71_RS12785	COG2271	Major facilitator Superfamily
GXP71_RS12790	COG0628	permease
GXP71_RS12810	COG0667	Aldo Keto reductase
GXP71_RS12820	COG1834	amidinotransferase
GXP71_RS12825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GXP71_RS12850	COG0791	NLP P60 protein
GXP71_RS12850	COG3103	Sh3 type 3 domain protein
GXP71_RS12850	COG1388	LysM domain
GXP71_RS12860	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GXP71_RS12875	COG2814	Major facilitator Superfamily
GXP71_RS12890	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GXP71_RS12925	COG0438	transferase activity, transferring glycosyl groups
GXP71_RS12930	COG0438	transferase activity, transferring glycosyl groups
GXP71_RS12940	COG0489	protein tyrosine kinase activity
GXP71_RS12945	COG1045	serine acetyltransferase
GXP71_RS12970	COG2252	PERMEase
GXP71_RS12990	COG0745	RESPONSE REGULATOR receiver
GXP71_RS13000	COG0745	RESPONSE REGULATOR receiver
GXP71_RS13010	COG2201	protein-glutamate methylesterase activity
GXP71_RS13025	COG0835	chemotaxis
GXP71_RS13030	COG0784	Response regulator, receiver
GXP71_RS13030	COG0643	Histidine kinase
GXP71_RS13030	COG2198	Histidine kinase
GXP71_RS13035	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GXP71_RS13060	COG0840	transmembrane signaling receptor activity
GXP71_RS13085	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GXP71_RS13090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GXP71_RS13105	COG1338	Plays a role in the flagellum-specific transport system
GXP71_RS13115	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GXP71_RS13115	COG1776	CheC inhibitor of MCP methylation
GXP71_RS13120	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GXP71_RS13145	COG1162	GTPase activity
GXP71_RS13150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GXP71_RS13165	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GXP71_RS13185	COG0667	Aldo Keto reductase
GXP71_RS13205	COG0183	Belongs to the thiolase family
GXP71_RS13215	COG2030	dehydratase
GXP71_RS13230	COG0259	pyridoxamine-phosphate oxidase activity
GXP71_RS13240	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GXP71_RS13240	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GXP71_RS13260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GXP71_RS13290	COG0488	(ABC) transporter
GXP71_RS13345	COG0662	Cupin 2, conserved barrel domain protein
GXP71_RS13350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GXP71_RS13370	COG0047	phosphoribosylformylglycinamidine synthase activity
GXP71_RS13375	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GXP71_RS13400	COG1864	DNA RNA non-specific endonuclease
GXP71_RS13400	COG3591	Belongs to the peptidase S1B family
GXP71_RS13405	COG1120	ATPase activity
GXP71_RS13410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GXP71_RS13415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GXP71_RS13425	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GXP71_RS13430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GXP71_RS13440	COG0151	Belongs to the GarS family
GXP71_RS13455	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GXP71_RS13510	COG0395	ABC-type sugar transport system, permease component
GXP71_RS13515	COG1175	transmembrane transport
GXP71_RS13550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GXP71_RS13555	COG0300	oxidoreductase activity
GXP71_RS13560	COG0514	ATP-dependent DNA helicase (RecQ)
GXP71_RS13575	COG2314	TM2 domain
GXP71_RS13580	COG1609	Transcriptional regulator
GXP71_RS13585	COG4948	Mandelate Racemase Muconate Lactonizing
GXP71_RS13625	COG0395	ABC-type sugar transport system, permease component
GXP71_RS13630	COG4209	transmembrane transport
GXP71_RS13645	COG3458	cephalosporin-C deacetylase activity
GXP71_RS13650	COG0508	dehydrogenase complex catalyzes the overall conversion of
GXP71_RS13650	COG0596	Alpha beta hydrolase
GXP71_RS13655	COG0667	Aldo Keto reductase
GXP71_RS13660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GXP71_RS13670	COG0405	Gamma-glutamyltransferase
GXP71_RS13680	COG2186	Transcriptional regulator
GXP71_RS13685	COG1609	Transcriptional regulator
GXP71_RS13690	COG2721	sulfolactate sulfo-lyase activity
GXP71_RS13695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GXP71_RS13700	COG0800	Aldolase
GXP71_RS13710	COG1609	Transcriptional regulator
GXP71_RS13715	COG0246	Mannitol dehydrogenase
GXP71_RS13720	COG0673	inositol 2-dehydrogenase activity
GXP71_RS13755	COG1070	Carbohydrate kinase
GXP71_RS13760	COG1028	Short-chain dehydrogenase reductase Sdr
GXP71_RS13760	COG3347	Dehydrogenase
GXP71_RS13765	COG4952	isomerase
GXP71_RS13770	COG3254	rhamnose metabolic process
GXP71_RS13825	COG1725	Transcriptional regulator
GXP71_RS13835	COG3634	alkyl hydroperoxide reductase activity
GXP71_RS13865	COG0673	inositol 2-dehydrogenase activity
GXP71_RS13880	COG0577	efflux transmembrane transporter activity
GXP71_RS13885	COG1136	(ABC) transporter
GXP71_RS13910	COG0395	ABC-type sugar transport system, permease component
GXP71_RS13915	COG1175	transmembrane transport
GXP71_RS13930	COG2814	Major facilitator Superfamily
GXP71_RS13950	COG3401	FG-GAP repeat protein
GXP71_RS13970	COG1609	Transcriptional regulator
GXP71_RS13975	COG1175	transmembrane transport
GXP71_RS13980	COG0395	ABC-type sugar transport system, permease component
GXP71_RS14000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GXP71_RS14015	COG0667	Aldo Keto reductase
GXP71_RS14025	COG2226	methyltransferase
GXP71_RS14045	COG0477	Major facilitator Superfamily
GXP71_RS14075	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GXP71_RS14075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GXP71_RS14080	COG0662	Cupin 2, conserved barrel domain protein
GXP71_RS14080	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GXP71_RS14100	COG0542	response to heat
GXP71_RS14105	COG0561	phosphatase activity
GXP71_RS14120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GXP71_RS14130	COG2409	Drug exporters of the RND superfamily
GXP71_RS14150	COG1472	Belongs to the glycosyl hydrolase 3 family
GXP71_RS14165	COG1490	D-aminoacyl-tRNA deacylase activity
GXP71_RS14190	COG3485	protocatechuate 3,4-dioxygenase
GXP71_RS14215	COG0745	RESPONSE REGULATOR receiver
GXP71_RS14220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GXP71_RS14225	COG0596	Alpha beta hydrolase
GXP71_RS14260	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GXP71_RS14265	COG1408	metallophosphoesterase
GXP71_RS14300	COG5297	Belongs to the glycosyl hydrolase family 6
GXP71_RS14300	COG4733	cellulase activity
GXP71_RS14310	COG1131	(ABC) transporter
GXP71_RS14320	COG1131	(ABC) transporter
GXP71_RS14335	COG2205	protein histidine kinase activity
GXP71_RS14360	COG1131	(ABC) transporter
GXP71_RS14380	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GXP71_RS14410	COG1129	ABC transporter
GXP71_RS14450	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GXP71_RS14485	COG3852	Histidine kinase
GXP71_RS14495	COG3401	FG-GAP repeat protein
GXP71_RS14500	COG1278	Cold shock
GXP71_RS14510	COG1278	Cold shock
GXP71_RS14515	COG3012	SEC-C Motif Domain Protein
GXP71_RS14530	COG1136	(ABC) transporter
GXP71_RS14545	COG2233	PERMEase
GXP71_RS14590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GXP71_RS14595	COG2365	Tyrosine phosphatase family
GXP71_RS14600	COG0431	NADPH-dependent FMN reductase
GXP71_RS14630	COG2186	Transcriptional regulator
GXP71_RS14665	COG2814	Major facilitator Superfamily
GXP71_RS14670	COG1609	Transcriptional regulator
GXP71_RS14695	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GXP71_RS14740	COG0667	Aldo Keto reductase
GXP71_RS14755	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GXP71_RS14765	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GXP71_RS14770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GXP71_RS14775	COG1780	Probably involved in ribonucleotide reductase function
GXP71_RS14800	COG1131	(ABC) transporter
GXP71_RS14805	COG1309	transcriptional regulator
GXP71_RS14810	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GXP71_RS14820	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GXP71_RS14845	COG2197	response regulator
GXP71_RS14875	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GXP71_RS14885	COG0531	amino acid
GXP71_RS14895	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GXP71_RS14900	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GXP71_RS14905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GXP71_RS14950	COG0586	Pfam SNARE associated Golgi protein
GXP71_RS15000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GXP71_RS15015	COG0058	SHG alpha-glucan phosphorylase activity
GXP71_RS15025	COG1511	domain protein
GXP71_RS15040	COG0577	efflux transmembrane transporter activity
GXP71_RS15040	COG1136	(ABC) transporter
GXP71_RS15045	COG0577	efflux transmembrane transporter activity
GXP71_RS15045	COG1136	(ABC) transporter
GXP71_RS15130	COG0667	Aldo Keto reductase
GXP71_RS15165	COG0557	exoribonuclease II activity
GXP71_RS15245	COG2018	Roadblock/LC7 domain
GXP71_RS15255	COG3321	synthase
GXP71_RS15255	COG1028	Short-chain dehydrogenase reductase Sdr
GXP71_RS15255	COG0604	alcohol dehydrogenase
GXP71_RS15270	COG5006	permease, DMT superfamily
GXP71_RS15275	COG0395	ABC-type sugar transport system, permease component
GXP71_RS15280	COG1175	transmembrane transport
GXP71_RS15285	COG1653	transport
GXP71_RS15290	COG0561	phosphatase activity
GXP71_RS15295	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GXP71_RS15310	COG0077	Prephenate dehydratase
GXP71_RS15320	COG1215	transferase activity, transferring glycosyl groups
GXP71_RS15350	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GXP71_RS15360	COG1215	transferase activity, transferring glycosyl groups
GXP71_RS15390	COG3265	gluconokinase activity
GXP71_RS15420	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GXP71_RS15420	COG4124	Belongs to the glycosyl hydrolase 26 family
GXP71_RS15445	COG0395	ABC-type sugar transport system, permease component
GXP71_RS15450	COG1175	transmembrane transport
GXP71_RS15490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GXP71_RS15495	COG3177	Filamentation induced by cAMP protein fic
GXP71_RS15505	COG1846	Transcriptional regulator
GXP71_RS15520	COG0583	DNA-binding transcription factor activity
GXP71_RS15600	COG1120	ATPase activity
GXP71_RS15630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS15645	COG2197	response regulator
GXP71_RS15660	COG0702	epimerase
GXP71_RS15665	COG1733	regulation of RNA biosynthetic process
GXP71_RS15685	COG1331	Highly conserved protein containing a thioredoxin domain
GXP71_RS15700	COG0009	L-threonylcarbamoyladenylate synthase
GXP71_RS15730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS15755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GXP71_RS15760	COG0531	amino acid
GXP71_RS15770	COG0789	Transcriptional regulator
GXP71_RS15795	COG0419	ATPase involved in DNA repair
GXP71_RS15800	COG0420	3'-5' exonuclease activity
GXP71_RS15815	COG0488	(ABC) transporter
GXP71_RS15825	COG1643	Atp-dependent helicase
GXP71_RS15845	COG0519	Catalyzes the synthesis of GMP from XMP
GXP71_RS15860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GXP71_RS15870	COG0494	nUDIX hydrolase
GXP71_RS15875	COG2197	response regulator
GXP71_RS15880	COG0509	glycine decarboxylation via glycine cleavage system
GXP71_RS15885	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GXP71_RS15890	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GXP71_RS15890	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GXP71_RS15905	COG0315	cyclic pyranopterin monophosphate synthase activity
GXP71_RS15905	COG0521	Mo-molybdopterin cofactor biosynthetic process
GXP71_RS15915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GXP71_RS15955	COG0746	molybdenum cofactor guanylyltransferase activity
GXP71_RS15960	COG0315	cyclic pyranopterin monophosphate synthase activity
GXP71_RS15990	COG0436	Aminotransferase
GXP71_RS15995	COG0598	Magnesium transport protein CorA
GXP71_RS16000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GXP71_RS16050	COG1674	ftsk spoiiie
GXP71_RS16120	COG0024	Methionine aminopeptidase
GXP71_RS16135	COG1610	YqeY-like protein
GXP71_RS16145	COG2357	RelA SpoT domain protein
GXP71_RS16150	COG1525	nuclease
GXP71_RS16170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GXP71_RS16195	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GXP71_RS16205	COG2337	Toxic component of a toxin-antitoxin (TA) module
GXP71_RS16215	COG0326	Molecular chaperone. Has ATPase activity
GXP71_RS16245	COG5297	Belongs to the glycosyl hydrolase family 6
GXP71_RS16245	COG4733	cellulase activity
GXP71_RS16265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS16375	COG1716	ATPase activity
GXP71_RS16390	COG0768	penicillin binding
GXP71_RS16395	COG0515	serine threonine protein kinase
GXP71_RS16400	COG0515	serine threonine protein kinase
GXP71_RS16410	COG3764	Sortase (surface protein transpeptidase)
GXP71_RS16425	COG0705	Rhomboid family
GXP71_RS16515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GXP71_RS16520	COG0187	DNA topoisomerase II activity
GXP71_RS16530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GXP71_RS16535	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GXP71_RS16540	COG0592	DNA-directed DNA polymerase activity
GXP71_RS16545	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GXP71_RS16550	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GXP71_RS16555	COG0594	ribonuclease P activity
GXP71_RS16560	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GXP71_RS16575	COG0357	Ribosomal RNA small subunit methyltransferase G
GXP71_RS16580	COG1192	Involved in chromosome partitioning
GXP71_RS16590	COG1181	Belongs to the D-alanine--D-alanine ligase family
GXP71_RS16595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GXP71_RS16600	COG3118	belongs to the thioredoxin family
GXP71_RS16630	COG0617	tRNA 3'-terminal CCA addition
GXP71_RS16635	COG4191	Histidine kinase
GXP71_RS16635	COG0784	Response regulator, receiver
GXP71_RS16660	COG1260	myo-inositol-1-phosphate synthase
GXP71_RS16670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GXP71_RS16675	COG0360	Binds together with S18 to 16S ribosomal RNA
GXP71_RS16685	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GXP71_RS16690	COG0359	binds to the 23S rRNA
GXP71_RS16705	COG0740	serine-type endopeptidase activity
GXP71_RS16710	COG0740	serine-type endopeptidase activity
GXP71_RS16715	COG1396	sequence-specific DNA binding
GXP71_RS16730	COG0534	Mate efflux family protein
GXP71_RS16735	COG1372	Participates in initiation and elongation during chromosome replication
GXP71_RS16735	COG0305	Participates in initiation and elongation during chromosome replication
GXP71_RS16765	COG3693	PFAM glycoside hydrolase, family 10
GXP71_RS16770	COG2273	Hydrolase Family 16
GXP71_RS16785	COG1280	lysine exporter protein (LysE YggA)
GXP71_RS16795	COG0148	phosphopyruvate hydratase activity
GXP71_RS16815	COG1181	Belongs to the D-alanine--D-alanine ligase family
GXP71_RS16830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GXP71_RS16835	COG0406	alpha-ribazole phosphatase activity
GXP71_RS16845	COG1028	Short-chain dehydrogenase reductase Sdr
GXP71_RS16855	COG1228	amidohydrolase
GXP71_RS16870	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GXP71_RS16875	COG2986	histidine ammonia-lyase
GXP71_RS16890	COG1472	Belongs to the glycosyl hydrolase 3 family
GXP71_RS16900	COG1609	Transcriptional regulator
GXP71_RS17030	COG0693	protein deglycase activity
GXP71_RS17055	COG2318	DinB family
GXP71_RS17065	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GXP71_RS17075	COG1316	TRANSCRIPTIONal
GXP71_RS17095	COG2860	membrane
GXP71_RS17100	COG1473	amidohydrolase
GXP71_RS17105	COG0789	Transcriptional regulator
GXP71_RS17120	COG4941	Belongs to the sigma-70 factor family
GXP71_RS17125	COG0596	Alpha beta hydrolase
GXP71_RS17145	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GXP71_RS17155	COG1472	Belongs to the glycosyl hydrolase 3 family
GXP71_RS17185	COG0514	ATP-dependent DNA helicase (RecQ)
GXP71_RS17185	COG0514	ATP-dependent DNA helicase (RecQ)
GXP71_RS17200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS17205	COG0457	Tetratricopeptide repeat
GXP71_RS17205	COG0705	Rhomboid family
GXP71_RS17215	COG4941	Belongs to the sigma-70 factor family
GXP71_RS17310	COG1222	aaa ATPase
GXP71_RS17320	COG0793	Belongs to the peptidase S41A family
GXP71_RS17320	COG4946	Tricorn protease homolog
GXP71_RS17325	COG2197	response regulator
GXP71_RS17340	COG5183	chlorophyll binding
GXP71_RS17340	COG2133	pyrroloquinoline quinone binding
GXP71_RS17350	COG1971	Probably functions as a manganese efflux pump
GXP71_RS17355	COG0640	Transcriptional regulator
GXP71_RS17375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS17390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GXP71_RS17455	COG1358	cellular component organization or biogenesis
GXP71_RS17515	COG1131	(ABC) transporter
GXP71_RS17535	COG1937	Protein conserved in bacteria
GXP71_RS17540	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GXP71_RS17550	COG4208	sulfate ABC transporter
GXP71_RS17555	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GXP71_RS17570	COG0730	response to heat
GXP71_RS17585	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GXP71_RS17590	COG0113	porphobilinogen synthase activity
GXP71_RS17600	COG0181	hydroxymethylbilane synthase activity
GXP71_RS17610	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GXP71_RS17625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GXP71_RS17635	COG5006	permease, DMT superfamily
GXP71_RS17650	COG1950	PFAM Membrane protein of
GXP71_RS17660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GXP71_RS17675	COG0022	dehydrogenase e1 component
GXP71_RS17680	COG0508	dehydrogenase complex catalyzes the overall conversion of
GXP71_RS17695	COG0477	Major facilitator Superfamily
GXP71_RS17730	COG0823	Involved in the tonB-independent uptake of proteins
GXP71_RS17730	COG1506	peptidase
GXP71_RS17760	COG0456	acetyltransferase
GXP71_RS17830	COG2813	Specifically methylates the guanine in position
GXP71_RS17850	COG1012	belongs to the aldehyde dehydrogenase family
GXP71_RS17880	COG3387	PFAM Glycoside hydrolase 15-related
GXP71_RS17905	COG0456	acetyltransferase
GXP71_RS17930	COG3459	Glycosyltransferase 36 associated
GXP71_RS17935	COG0717	Belongs to the dCTP deaminase family
GXP71_RS17955	COG1132	(ABC) transporter
GXP71_RS17975	COG2181	nitrate reductase activity
GXP71_RS17975	COG0247	lactate metabolic process
GXP71_RS17980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GXP71_RS17980	COG2111	Na H antiporter
GXP71_RS18000	COG2212	antiporter activity
GXP71_RS18030	COG3842	ATPase activity
GXP71_RS18055	COG4941	Belongs to the sigma-70 factor family
GXP71_RS18065	COG3795	YCII-related domain
GXP71_RS18070	COG0640	Transcriptional regulator
GXP71_RS18075	COG0346	lactoylglutathione lyase activity
GXP71_RS18080	COG3401	FG-GAP repeat protein
GXP71_RS18105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GXP71_RS18155	COG2409	Drug exporters of the RND superfamily
GXP71_RS18170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GXP71_RS18175	COG0402	S-adenosylhomocysteine deaminase activity
GXP71_RS18195	COG0667	Aldo Keto reductase
GXP71_RS18200	COG4106	trans-aconitate 2-methyltransferase activity
GXP71_RS18220	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GXP71_RS18230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GXP71_RS18235	COG0471	metal ion transport
GXP71_RS18235	COG0490	domain, Protein
GXP71_RS18250	COG2226	methyltransferase
GXP71_RS18255	COG1678	Uncharacterized ACR, COG1678
GXP71_RS18270	COG3655	Transcriptional regulator
GXP71_RS18300	COG0477	Major facilitator Superfamily
GXP71_RS18320	COG1966	Carbon starvation protein
GXP71_RS18340	COG0738	Major facilitator superfamily
GXP71_RS18365	COG0640	Transcriptional regulator
GXP71_RS18405	COG2267	carboxylic ester hydrolase activity
GXP71_RS18415	COG2249	NAD(P)H dehydrogenase (quinone) activity
GXP71_RS18420	COG0110	maltose O-acetyltransferase activity
GXP71_RS18430	COG0596	Alpha beta hydrolase
GXP71_RS18475	COG2207	Transcriptional regulator
GXP71_RS18475	COG3708	Transcriptional regulator
GXP71_RS18490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GXP71_RS18495	COG2318	DinB family
GXP71_RS18545	COG1595	DNA-templated transcription, initiation
GXP71_RS18555	COG1131	(ABC) transporter
GXP71_RS18575	COG2197	response regulator
GXP71_RS18585	COG2267	carboxylic ester hydrolase activity
GXP71_RS18595	COG0187	DNA topoisomerase II activity
GXP71_RS18615	COG2226	methyltransferase
GXP71_RS18635	COG1028	Short-chain dehydrogenase reductase Sdr
GXP71_RS18645	COG1278	Cold shock
GXP71_RS18685	COG3345	alpha-galactosidase
GXP71_RS18745	COG0443	Heat shock 70 kDa protein
GXP71_RS18750	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GXP71_RS18755	COG0484	heat shock protein binding
GXP71_RS18760	COG0789	Transcriptional regulator
GXP71_RS18775	COG2205	protein histidine kinase activity
GXP71_RS18780	COG0745	RESPONSE REGULATOR receiver
GXP71_RS18785	COG1309	transcriptional regulator
GXP71_RS18805	COG0601	transmembrane transport
GXP71_RS18810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GXP71_RS18860	COG1754	DNA topoisomerase type I activity
GXP71_RS18860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GXP71_RS18870	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GXP71_RS18875	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GXP71_RS18880	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GXP71_RS19000	COG1674	ftsk spoiiie
GXP71_RS19010	COG1690	Belongs to the RtcB family
GXP71_RS19020	COG1876	peptidase activity
GXP71_RS19025	COG0477	Major facilitator Superfamily
GXP71_RS19040	COG2197	response regulator
GXP71_RS19050	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GXP71_RS19095	COG1175	transmembrane transport
GXP71_RS19100	COG0395	ABC-type sugar transport system, permease component
GXP71_RS19115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GXP71_RS19130	COG0328	RNA-DNA hybrid ribonuclease activity
GXP71_RS19140	COG1404	Belongs to the peptidase S8 family
GXP71_RS19145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GXP71_RS19160	COG1672	PFAM Archaeal ATPase
GXP71_RS19160	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GXP71_RS19170	COG0277	FAD linked oxidase domain protein
GXP71_RS19170	COG0247	lactate metabolic process
GXP71_RS19195	COG0604	alcohol dehydrogenase
GXP71_RS19210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GXP71_RS19215	COG2873	o-acetylhomoserine
GXP71_RS19220	COG0791	NLP P60 protein
GXP71_RS19220	COG3883	PFAM NLP P60 protein
GXP71_RS19225	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GXP71_RS19230	COG2027	D-alanyl-D-alanine carboxypeptidase
GXP71_RS19240	COG0037	tRNA processing
GXP71_RS19250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GXP71_RS19255	COG0302	gtp cyclohydrolase
GXP71_RS19260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GXP71_RS19265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GXP71_RS19290	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GXP71_RS19310	COG0157	Belongs to the NadC ModD family
GXP71_RS19315	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GXP71_RS19330	COG3693	PFAM glycoside hydrolase, family 10
GXP71_RS19335	COG1070	Carbohydrate kinase
GXP71_RS19340	COG2115	Belongs to the xylose isomerase family
GXP71_RS19345	COG1940	carbohydrate kinase activity
GXP71_RS19345	COG1846	Transcriptional regulator
GXP71_RS19350	COG2706	6-phosphogluconolactonase activity
GXP71_RS19360	COG0438	transferase activity, transferring glycosyl groups
GXP71_RS19365	COG0588	phosphoglycerate mutase activity
GXP71_RS19395	COG5002	protein histidine kinase activity
GXP71_RS19400	COG0745	RESPONSE REGULATOR receiver
GXP71_RS19420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GXP71_RS19430	COG1329	Transcriptional regulator
GXP71_RS19435	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GXP71_RS19440	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GXP71_RS19470	COG3226	Transcriptional regulator
GXP71_RS19475	COG0738	Major facilitator superfamily
GXP71_RS19485	COG0215	cysteine-tRNA ligase activity
GXP71_RS19490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GXP71_RS19505	COG3842	ATPase activity
GXP71_RS19520	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GXP71_RS19525	COG0515	serine threonine protein kinase
GXP71_RS19525	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GXP71_RS19550	COG1609	Transcriptional regulator
GXP71_RS19610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GXP71_RS19625	COG1278	Cold shock
GXP71_RS19635	COG0459	protein refolding
GXP71_RS19720	COG2205	protein histidine kinase activity
GXP71_RS19725	COG0745	RESPONSE REGULATOR receiver
GXP71_RS19745	COG0505	Belongs to the CarA family
GXP71_RS19750	COG1842	Phage shock protein A
GXP71_RS19765	COG1061	Type III restriction enzyme res subunit
GXP71_RS19775	COG1473	amidohydrolase
GXP71_RS19780	COG1278	Cold shock
GXP71_RS19795	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GXP71_RS19800	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GXP71_RS19810	COG4786	Flagellar basal body rod
GXP71_RS19810	COG1256	bacterial-type flagellum assembly
GXP71_RS19820	COG1191	sigma factor activity
GXP71_RS19845	COG1815	bacterial-type flagellum-dependent cell motility
GXP71_RS19855	COG1677	Flagellar hook-basal body complex protein FliE
GXP71_RS19865	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GXP71_RS19885	COG0791	NLP P60 protein
GXP71_RS19925	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GXP71_RS19975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GXP71_RS20015	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates