locus-tag	class	description
CELAL_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CELAL_RS00010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CELAL_RS00025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CELAL_RS00035	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CELAL_RS00040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CELAL_RS00055	COG0336	Belongs to the RNA methyltransferase TrmD family
CELAL_RS00060	COG0335	large ribosomal subunit rRNA binding
CELAL_RS00145	COG1363	Peptidase, m42
CELAL_RS00150	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CELAL_RS00155	COG0124	histidyl-tRNA synthetase
CELAL_RS00170	COG0359	binds to the 23S rRNA
CELAL_RS00175	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CELAL_RS00180	COG0360	Binds together with S18 to 16S ribosomal RNA
CELAL_RS00185	COG3279	Response regulator of the LytR AlgR family
CELAL_RS00190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CELAL_RS00200	COG1295	ribonuclease BN
CELAL_RS00210	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CELAL_RS00220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CELAL_RS00240	COG2020	methyltransferase activity
CELAL_RS00245	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CELAL_RS00250	COG0513	Belongs to the DEAD box helicase family
CELAL_RS00260	COG0366	Alpha amylase catalytic
CELAL_RS00265	COG1408	metallophosphoesterase
CELAL_RS00275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CELAL_RS00285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CELAL_RS00290	COG0668	transmembrane transport
CELAL_RS00335	COG4206	TonB-dependent receptor
CELAL_RS00345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CELAL_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
CELAL_RS00390	COG0363	glucosamine-6-phosphate deaminase activity
CELAL_RS00395	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CELAL_RS00400	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CELAL_RS00425	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CELAL_RS00435	COG1388	LysM domain
CELAL_RS00435	COG0741	lytic transglycosylase activity
CELAL_RS00450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELAL_RS00460	COG0254	rRNA binding
CELAL_RS00475	COG0463	Glycosyl transferase, family 2
CELAL_RS00480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CELAL_RS00485	COG1132	(ABC) transporter
CELAL_RS00510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CELAL_RS00510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CELAL_RS00530	COG1022	Amp-dependent synthetase and ligase
CELAL_RS00540	COG1024	Enoyl-CoA hydratase
CELAL_RS00540	COG1250	3-hydroxyacyl-CoA dehydrogenase
CELAL_RS00545	COG0183	Belongs to the thiolase family
CELAL_RS00550	COG1960	acyl-CoA dehydrogenase activity
CELAL_RS00555	COG3387	PFAM Glycoside hydrolase 15-related
CELAL_RS00590	COG3217	Mosc domain protein beta barrel domain protein
CELAL_RS00590	COG0633	Ferredoxin
CELAL_RS00670	COG0793	Belongs to the peptidase S41A family
CELAL_RS00675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CELAL_RS00800	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CELAL_RS00845	COG3781	membrane
CELAL_RS00865	COG0564	pseudouridine synthase activity
CELAL_RS00985	COG3279	Response regulator of the LytR AlgR family
CELAL_RS01005	COG3275	phosphorelay sensor kinase activity
CELAL_RS01015	COG4565	transcriptional regulatory protein
CELAL_RS01020	COG1522	sequence-specific DNA binding
CELAL_RS01025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CELAL_RS01030	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CELAL_RS01035	COG1187	pseudouridine synthase activity
CELAL_RS01040	COG0513	Belongs to the DEAD box helicase family
CELAL_RS01045	COG0629	single-stranded DNA binding
CELAL_RS01140	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CELAL_RS01145	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CELAL_RS01195	COG3547	Transposase (IS116 IS110 IS902 family)
CELAL_RS01210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CELAL_RS01220	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CELAL_RS01230	COG1733	regulation of RNA biosynthetic process
CELAL_RS01275	COG2205	protein histidine kinase activity
CELAL_RS01275	COG0745	RESPONSE REGULATOR receiver
CELAL_RS01275	COG3292	Two component regulator propeller
CELAL_RS01280	COG5002	protein histidine kinase activity
CELAL_RS01285	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CELAL_RS01315	COG0300	oxidoreductase activity
CELAL_RS01370	COG3263	regulation of cellular component size
CELAL_RS01385	COG0784	Response regulator, receiver
CELAL_RS01385	COG2198	Histidine kinase
CELAL_RS01385	COG0643	Histidine kinase
CELAL_RS01405	COG0531	amino acid
CELAL_RS01415	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CELAL_RS01425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CELAL_RS01440	COG0659	secondary active sulfate transmembrane transporter activity
CELAL_RS01470	COG1785	Belongs to the alkaline phosphatase family
CELAL_RS01505	COG2706	6-phosphogluconolactonase activity
CELAL_RS01515	COG5002	protein histidine kinase activity
CELAL_RS01525	COG0242	peptide deformylase activity
CELAL_RS01530	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CELAL_RS01535	COG2171	N-acyltransferase activity
CELAL_RS01550	COG0463	Glycosyl transferase, family 2
CELAL_RS01560	COG0009	L-threonylcarbamoyladenylate synthase
CELAL_RS01565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CELAL_RS01565	COG0617	tRNA 3'-terminal CCA addition
CELAL_RS01565	COG0517	IMP dehydrogenase activity
CELAL_RS01585	COG1612	heme a metabolic process
CELAL_RS01610	COG1131	(ABC) transporter
CELAL_RS01625	COG0556	nucleotide-excision repair
CELAL_RS01630	COG0071	Belongs to the small heat shock protein (HSP20) family
CELAL_RS01645	COG0045	succinate-CoA ligase (ADP-forming) activity
CELAL_RS01660	COG2897	thiosulfate sulfurtransferase activity
CELAL_RS01670	COG0517	IMP dehydrogenase activity
CELAL_RS01670	COG0516	GMP reductase activity
CELAL_RS01695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CELAL_RS01710	COG0167	dihydroorotate dehydrogenase activity
CELAL_RS01720	COG4206	TonB-dependent receptor
CELAL_RS01720	COG1629	transport
CELAL_RS01725	COG2195	Cleaves the N-terminal amino acid of tripeptides
CELAL_RS01730	COG1862	Preprotein translocase
CELAL_RS01740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CELAL_RS01745	COG1132	(ABC) transporter
CELAL_RS01765	COG0385	Bile acid
CELAL_RS01770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CELAL_RS01780	COG0450	alkyl hydroperoxide reductase
CELAL_RS01785	COG1278	Cold shock
CELAL_RS01790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CELAL_RS01795	COG3590	peptidase
CELAL_RS01805	COG2326	polyphosphate kinase activity
CELAL_RS01815	COG2204	response regulator
CELAL_RS01820	COG1196	nuclear chromosome segregation
CELAL_RS01820	COG3264	Mechanosensitive ion channel
CELAL_RS01825	COG1668	transmembrane transport
CELAL_RS01830	COG4152	abc transporter atp-binding protein
CELAL_RS01840	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CELAL_RS01860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CELAL_RS01880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CELAL_RS01885	COG0347	Belongs to the P(II) protein family
CELAL_RS01890	COG0004	ammonium transporteR
CELAL_RS01900	COG0347	Belongs to the P(II) protein family
CELAL_RS01905	COG0004	ammonium transporteR
CELAL_RS01925	COG1522	sequence-specific DNA binding
CELAL_RS01935	COG1703	isobutyryl-CoA mutase activity
CELAL_RS01935	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CELAL_RS01935	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CELAL_RS01940	COG0788	formyltetrahydrofolate deformylase activity
CELAL_RS01960	COG0284	orotidine-5'-phosphate decarboxylase activity
CELAL_RS01965	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CELAL_RS01995	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CELAL_RS02005	COG0174	glutamine synthetase
CELAL_RS02035	COG2321	neutral zinc metallopeptidase
CELAL_RS02045	COG2207	Transcriptional regulator
CELAL_RS02060	COG4948	Mandelate Racemase Muconate Lactonizing
CELAL_RS02075	COG0800	Aldolase
CELAL_RS02085	COG2271	Major facilitator Superfamily
CELAL_RS02090	COG4948	Mandelate Racemase Muconate Lactonizing
CELAL_RS02095	COG3119	arylsulfatase activity
CELAL_RS02100	COG3119	arylsulfatase activity
CELAL_RS02110	COG2814	Major facilitator Superfamily
CELAL_RS02125	COG3119	arylsulfatase activity
CELAL_RS02130	COG3119	arylsulfatase activity
CELAL_RS02135	COG3119	arylsulfatase activity
CELAL_RS02145	COG0445	tRNA wobble uridine modification
CELAL_RS02155	COG4771	TonB-dependent receptor
CELAL_RS02235	COG0738	Major facilitator superfamily
CELAL_RS02240	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CELAL_RS02250	COG3292	Two component regulator propeller
CELAL_RS02250	COG2205	protein histidine kinase activity
CELAL_RS02250	COG0745	RESPONSE REGULATOR receiver
CELAL_RS02260	COG1304	FMN binding
CELAL_RS02270	COG0544	peptidyl-prolyl cis-trans isomerase activity
CELAL_RS02275	COG4771	TonB-dependent receptor
CELAL_RS02290	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CELAL_RS02295	COG1085	galactose-1-phosphate uridylyltransferase
CELAL_RS02315	COG0673	inositol 2-dehydrogenase activity
CELAL_RS02340	COG0702	epimerase
CELAL_RS02345	COG1629	transport
CELAL_RS02365	COG2264	protein methyltransferase activity
CELAL_RS02370	COG0149	triose-phosphate isomerase activity
CELAL_RS02385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CELAL_RS02400	COG1132	(ABC) transporter
CELAL_RS02405	COG0101	tRNA pseudouridine synthase activity
CELAL_RS02445	COG0268	Binds directly to 16S ribosomal RNA
CELAL_RS02460	COG0442	prolyl-tRNA aminoacylation
CELAL_RS02485	COG0302	gtp cyclohydrolase
CELAL_RS02490	COG0215	cysteine-tRNA ligase activity
CELAL_RS02495	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CELAL_RS02510	COG1119	ATPase activity
CELAL_RS02515	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CELAL_RS02520	COG0039	L-malate dehydrogenase activity
CELAL_RS02545	COG0187	DNA topoisomerase II activity
CELAL_RS02550	COG0367	asparagine synthase
CELAL_RS02560	COG1289	transmembrane transporter activity
CELAL_RS02565	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CELAL_RS02570	COG0579	oxidoreductase
CELAL_RS02575	COG0488	(ABC) transporter
CELAL_RS02610	COG2205	protein histidine kinase activity
CELAL_RS02615	COG2884	Cell division ATP-binding protein ftsE
CELAL_RS02625	COG1940	carbohydrate kinase activity
CELAL_RS02635	COG1217	gtp-binding protein TYPA
CELAL_RS02640	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CELAL_RS02720	COG1538	Outer membrane efflux protein
CELAL_RS02765	COG2176	DNA-directed DNA polymerase activity
CELAL_RS02770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CELAL_RS02770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CELAL_RS02795	COG3876	Protein conserved in bacteria
CELAL_RS02820	COG0500	methyltransferase
CELAL_RS02830	COG0602	queuosine metabolic process
CELAL_RS02835	COG0433	COG0433 Predicted ATPase
CELAL_RS02850	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CELAL_RS02850	COG0662	Cupin 2, conserved barrel domain protein
CELAL_RS02870	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CELAL_RS02875	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CELAL_RS02905	COG0018	arginyl-trna synthetase
CELAL_RS02920	COG0702	epimerase
CELAL_RS02925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CELAL_RS02950	COG0148	phosphopyruvate hydratase activity
CELAL_RS02955	COG0505	Belongs to the CarA family
CELAL_RS02960	COG0203	ribosomal protein L17
CELAL_RS02965	COG0202	RNA polymerase activity
CELAL_RS02970	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CELAL_RS02975	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CELAL_RS02980	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CELAL_RS02985	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CELAL_RS02995	COG0200	Binds to the 23S rRNA
CELAL_RS03000	COG1841	ribosomal large subunit assembly
CELAL_RS03005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CELAL_RS03010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CELAL_RS03015	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CELAL_RS03020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CELAL_RS03025	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CELAL_RS03030	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CELAL_RS03035	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CELAL_RS03040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CELAL_RS03045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CELAL_RS03050	COG0255	Belongs to the universal ribosomal protein uL29 family
CELAL_RS03055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CELAL_RS03060	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CELAL_RS03065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CELAL_RS03070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CELAL_RS03075	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CELAL_RS03080	COG0089	rRNA binding
CELAL_RS03085	COG0088	Forms part of the polypeptide exit tunnel
CELAL_RS03090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CELAL_RS03095	COG0051	transcription antitermination factor activity, RNA binding
CELAL_RS03100	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CELAL_RS03105	COG0049	tRNA binding
CELAL_RS03110	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CELAL_RS03120	COG4771	TonB-dependent receptor
CELAL_RS03130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CELAL_RS03140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CELAL_RS03160	COG1011	Hydrolase
CELAL_RS03170	COG2003	Belongs to the UPF0758 family
CELAL_RS03180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CELAL_RS03190	COG1028	Short-chain dehydrogenase reductase Sdr
CELAL_RS03200	COG4771	TonB-dependent receptor
CELAL_RS03225	COG3275	phosphorelay sensor kinase activity
CELAL_RS03290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CELAL_RS03295	COG0563	adenylate kinase activity
CELAL_RS03300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CELAL_RS03310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CELAL_RS03440	COG3177	Filamentation induced by cAMP protein fic
CELAL_RS03550	COG1090	epimerase
CELAL_RS03575	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CELAL_RS03575	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CELAL_RS03595	COG1595	DNA-templated transcription, initiation
CELAL_RS03605	COG1733	regulation of RNA biosynthetic process
CELAL_RS03645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CELAL_RS03670	COG1028	Short-chain dehydrogenase reductase Sdr
CELAL_RS03675	COG2234	aminopeptidase activity
CELAL_RS03685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CELAL_RS03690	COG0295	cytidine deaminase activity
CELAL_RS03705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CELAL_RS03710	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CELAL_RS03715	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CELAL_RS03720	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CELAL_RS03735	COG0702	epimerase
CELAL_RS03740	COG4771	TonB-dependent receptor
CELAL_RS03755	COG0285	dihydrofolate synthase activity
CELAL_RS03765	COG0848	biopolymer transport protein
CELAL_RS03770	COG0811	peptide transport
CELAL_RS03780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CELAL_RS03785	COG1960	acyl-CoA dehydrogenase activity
CELAL_RS03790	COG0069	glutamate synthase activity
CELAL_RS03790	COG0067	glutamate synthase
CELAL_RS03790	COG0070	glutamate synthase
CELAL_RS03815	COG4206	TonB-dependent receptor
CELAL_RS03815	COG1629	transport
CELAL_RS03825	COG1595	DNA-templated transcription, initiation
CELAL_RS03865	COG0702	epimerase
CELAL_RS03870	COG1629	transport
CELAL_RS03875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CELAL_RS03890	COG0321	lipoyl(octanoyl) transferase activity
CELAL_RS03895	COG0401	homolog of Blt101
CELAL_RS03900	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CELAL_RS03915	COG2723	6-phospho-beta-galactosidase activity
CELAL_RS03925	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CELAL_RS03930	COG1705	Flagellar rod assembly protein muramidase FlgJ
CELAL_RS03930	COG3942	CHAP domain
CELAL_RS03935	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CELAL_RS03950	COG3186	Phenylalanine-4-hydroxylase
CELAL_RS03965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CELAL_RS03970	COG0739	heme binding
CELAL_RS04000	COG1160	GTP binding
CELAL_RS04010	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CELAL_RS04015	COG1115	amino acid carrier protein
CELAL_RS04055	COG1525	nuclease
CELAL_RS04175	COG4585	Histidine kinase
CELAL_RS04185	COG1609	Transcriptional regulator
CELAL_RS04195	COG3507	Belongs to the glycosyl hydrolase 43 family
CELAL_RS04200	COG2814	Major facilitator Superfamily
CELAL_RS04205	COG0673	inositol 2-dehydrogenase activity
CELAL_RS04210	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CELAL_RS04215	COG3959	Transketolase, thiamine diphosphate binding domain
CELAL_RS04220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CELAL_RS04230	COG2211	Major facilitator Superfamily
CELAL_RS04245	COG3693	PFAM glycoside hydrolase, family 10
CELAL_RS04265	COG4771	TonB-dependent receptor
CELAL_RS04270	COG3292	Two component regulator propeller
CELAL_RS04270	COG2205	protein histidine kinase activity
CELAL_RS04270	COG0745	RESPONSE REGULATOR receiver
CELAL_RS04275	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CELAL_RS04280	COG1331	Highly conserved protein containing a thioredoxin domain
CELAL_RS04285	COG2207	Transcriptional regulator
CELAL_RS04340	COG0488	(ABC) transporter
CELAL_RS04370	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CELAL_RS04395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELAL_RS04420	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CELAL_RS04425	COG0459	protein refolding
CELAL_RS04465	COG0138	bifunctional purine biosynthesis protein purh
CELAL_RS04470	COG1077	Cell shape determining protein MreB Mrl
CELAL_RS04485	COG0768	penicillin binding
CELAL_RS04490	COG0772	Belongs to the SEDS family
CELAL_RS04500	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CELAL_RS04510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CELAL_RS04520	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CELAL_RS04525	COG0791	NLP P60 protein
CELAL_RS04530	COG2333	competence protein COMEC
CELAL_RS04530	COG0658	competence protein
CELAL_RS04535	COG3104	oligopeptide transport
CELAL_RS04540	COG0823	Involved in the tonB-independent uptake of proteins
CELAL_RS04540	COG1506	peptidase
CELAL_RS04555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CELAL_RS04585	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CELAL_RS04615	COG1629	transport
CELAL_RS04620	COG0702	epimerase
CELAL_RS04625	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CELAL_RS04635	COG0425	Belongs to the sulfur carrier protein TusA family
CELAL_RS04635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CELAL_RS04645	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CELAL_RS04655	COG1215	transferase activity, transferring glycosyl groups
CELAL_RS04690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CELAL_RS04710	COG1215	transferase activity, transferring glycosyl groups
CELAL_RS04725	COG0137	argininosuccinate synthase activity
CELAL_RS04730	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CELAL_RS04745	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CELAL_RS04750	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CELAL_RS04755	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CELAL_RS04760	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CELAL_RS04770	COG0165	Argininosuccinate lyase
CELAL_RS04780	COG1187	pseudouridine synthase activity
CELAL_RS04805	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CELAL_RS04820	COG2081	HI0933 family
CELAL_RS04825	COG0584	glycerophosphoryl diester phosphodiesterase
CELAL_RS04835	COG1554	hydrolase, family 65, central catalytic
CELAL_RS04840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CELAL_RS04850	COG4206	TonB-dependent receptor
CELAL_RS04850	COG1629	transport
CELAL_RS04855	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CELAL_RS04880	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CELAL_RS04905	COG2204	response regulator
CELAL_RS04910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CELAL_RS04915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CELAL_RS04970	COG1132	(ABC) transporter
CELAL_RS04975	COG0633	Ferredoxin
CELAL_RS04985	COG0489	protein tyrosine kinase activity
CELAL_RS05000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CELAL_RS05005	COG5002	protein histidine kinase activity
CELAL_RS05010	COG0745	RESPONSE REGULATOR receiver
CELAL_RS05015	COG4771	TonB-dependent receptor
CELAL_RS05045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CELAL_RS05060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CELAL_RS05065	COG0463	Glycosyl transferase, family 2
CELAL_RS05085	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CELAL_RS05090	COG2363	Small membrane protein
CELAL_RS05100	COG1522	sequence-specific DNA binding
CELAL_RS05110	COG0686	Belongs to the AlaDH PNT family
CELAL_RS05115	COG0495	leucyl-tRNA aminoacylation
CELAL_RS05120	COG2177	Part of the ABC transporter FtsEX involved in
CELAL_RS05130	COG1968	undecaprenyl-diphosphatase activity
CELAL_RS05135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CELAL_RS05150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CELAL_RS05165	COG1132	(ABC) transporter
CELAL_RS05180	COG0519	Catalyzes the synthesis of GMP from XMP
CELAL_RS05195	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CELAL_RS05205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CELAL_RS05230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CELAL_RS05240	COG0673	inositol 2-dehydrogenase activity
CELAL_RS05310	COG3201	nicotinamide mononucleotide transporter
CELAL_RS05330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CELAL_RS05345	COG1629	transport
CELAL_RS05370	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CELAL_RS05375	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CELAL_RS05390	COG0612	Peptidase, M16
CELAL_RS05410	COG0629	single-stranded DNA binding
CELAL_RS05420	COG0776	regulation of translation
CELAL_RS05425	COG1530	ribonuclease E activity
CELAL_RS05430	COG2137	regulation of response to DNA damage stimulus
CELAL_RS05445	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CELAL_RS05450	COG2268	Band 7 protein
CELAL_RS05465	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CELAL_RS05480	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CELAL_RS05575	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CELAL_RS05580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CELAL_RS05590	COG0489	protein tyrosine kinase activity
CELAL_RS05630	COG0297	glycogen (starch) synthase activity
CELAL_RS05740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CELAL_RS05750	COG0297	glycogen (starch) synthase activity
CELAL_RS05755	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CELAL_RS05760	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CELAL_RS05785	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CELAL_RS05790	COG0667	Aldo Keto reductase
CELAL_RS05795	COG0708	Exodeoxyribonuclease III
CELAL_RS05805	COG2885	chlorophyll binding
CELAL_RS05825	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CELAL_RS05830	COG0423	glycine-tRNA ligase activity
CELAL_RS05840	COG1040	competence protein
CELAL_RS05870	COG3850	Histidine kinase
CELAL_RS05870	COG5002	protein histidine kinase activity
CELAL_RS05905	COG0166	Belongs to the GPI family
CELAL_RS05915	COG3483	tryptophan 2,3-dioxygenase activity
CELAL_RS05925	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CELAL_RS05930	COG1752	Esterase of the alpha-beta hydrolase superfamily
CELAL_RS05935	COG0322	excinuclease ABC activity
CELAL_RS05940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CELAL_RS05945	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CELAL_RS05960	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CELAL_RS05970	COG4771	TonB-dependent receptor
CELAL_RS05975	COG1381	Involved in DNA repair and RecF pathway recombination
CELAL_RS05995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CELAL_RS06000	COG0626	cystathionine gamma-synthase activity
CELAL_RS06045	COG0352	thiamine-phosphate diphosphorylase activity
CELAL_RS06045	COG0351	phosphomethylpyrimidine kinase
CELAL_RS06050	COG0659	secondary active sulfate transmembrane transporter activity
CELAL_RS06060	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CELAL_RS06065	COG4953	penicillin-binding protein 1C
CELAL_RS06070	COG2329	Antibiotic biosynthesis monooxygenase
CELAL_RS06100	COG0662	Cupin 2, conserved barrel domain protein
CELAL_RS06110	COG1012	belongs to the aldehyde dehydrogenase family
CELAL_RS06140	COG4260	virion core protein, lumpy skin disease virus
CELAL_RS06150	COG4221	oxidoreductase activity
CELAL_RS06155	COG4989	oxidoreductase activity
CELAL_RS06160	COG0714	Associated with various cellular activities
CELAL_RS06175	COG2304	oxidoreductase activity
CELAL_RS06180	COG2304	oxidoreductase activity
CELAL_RS06205	COG0659	secondary active sulfate transmembrane transporter activity
CELAL_RS06215	COG0288	reversible hydration of carbon dioxide
CELAL_RS06220	COG0288	reversible hydration of carbon dioxide
CELAL_RS06225	COG0659	secondary active sulfate transmembrane transporter activity
CELAL_RS06230	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CELAL_RS06245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CELAL_RS06255	COG1538	Outer membrane efflux protein
CELAL_RS06295	COG2954	triphosphatase activity
CELAL_RS06300	COG0702	epimerase
CELAL_RS06305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CELAL_RS06325	COG0469	pyruvate kinase activity
CELAL_RS06335	COG0571	ribonuclease III activity
CELAL_RS06340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CELAL_RS06345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CELAL_RS06355	COG0328	RNA-DNA hybrid ribonuclease activity
CELAL_RS06380	COG1074	ATP-dependent DNA helicase activity
CELAL_RS06390	COG2885	chlorophyll binding
CELAL_RS06390	COG3047	cAMP biosynthetic process
CELAL_RS06395	COG0210	DNA helicase
CELAL_RS06400	COG0300	oxidoreductase activity
CELAL_RS06425	COG4771	TonB-dependent receptor
CELAL_RS06435	COG2885	chlorophyll binding
CELAL_RS06480	COG0534	Mate efflux family protein
CELAL_RS06490	COG0720	synthase
CELAL_RS06495	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CELAL_RS06510	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CELAL_RS06510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CELAL_RS06540	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CELAL_RS06555	COG1435	thymidine kinase activity
CELAL_RS06560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CELAL_RS06565	COG1970	mechanosensitive ion channel activity
CELAL_RS06570	COG0745	RESPONSE REGULATOR receiver
CELAL_RS06575	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CELAL_RS06580	COG1505	serine-type exopeptidase activity
CELAL_RS06585	COG3842	ATPase activity
CELAL_RS06600	COG0545	Peptidyl-prolyl cis-trans isomerase
CELAL_RS06640	COG0439	Biotin carboxylase
CELAL_RS06645	COG0511	ligase activity, forming carbon-carbon bonds
CELAL_RS06650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CELAL_RS06655	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CELAL_RS06665	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CELAL_RS06690	COG0784	Response regulator, receiver
CELAL_RS06690	COG2198	Histidine kinase
CELAL_RS06690	COG2205	protein histidine kinase activity
CELAL_RS06695	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CELAL_RS06715	COG0243	molybdopterin cofactor binding
CELAL_RS06755	COG2223	nitrite transmembrane transporter activity
CELAL_RS06765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CELAL_RS06770	COG2146	nitrite reductase [NAD(P)H] activity
CELAL_RS06770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CELAL_RS06840	COG4245	von Willebrand factor, type A
CELAL_RS06865	COG2310	stress, protein
CELAL_RS06885	COG2310	stress, protein
CELAL_RS06890	COG0471	metal ion transport
CELAL_RS06930	COG0346	lactoylglutathione lyase activity
CELAL_RS06935	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CELAL_RS06960	COG0481	GTPase activity
CELAL_RS06985	COG0659	secondary active sulfate transmembrane transporter activity
CELAL_RS06995	COG2201	protein-glutamate methylesterase activity
CELAL_RS07015	COG0798	PFAM Bile acid sodium symporter
CELAL_RS07020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CELAL_RS07035	COG0594	ribonuclease P activity
CELAL_RS07040	COG0793	Belongs to the peptidase S41A family
CELAL_RS07120	COG3738	Protein conserved in bacteria
CELAL_RS07180	COG3657	addiction module killer protein
CELAL_RS07185	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CELAL_RS07290	COG0791	NLP P60 protein
CELAL_RS07310	COG2153	protein acetylation
CELAL_RS07315	COG1230	cation diffusion facilitator family transporter
CELAL_RS07320	COG0698	ribose 5-phosphate isomerase
CELAL_RS07325	COG0557	exoribonuclease II activity
CELAL_RS07375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CELAL_RS07385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CELAL_RS07395	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CELAL_RS07400	COG0445	tRNA wobble uridine modification
CELAL_RS07420	COG4682	membrane
CELAL_RS07490	COG0470	DNA polymerase III
CELAL_RS07495	COG0126	phosphoglycerate kinase activity
CELAL_RS07500	COG1388	LysM domain
CELAL_RS07500	COG1705	Flagellar rod assembly protein muramidase FlgJ
CELAL_RS07515	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CELAL_RS07530	COG1774	PSP1 C-terminal conserved region
CELAL_RS07535	COG1054	Belongs to the UPF0176 family
CELAL_RS07540	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CELAL_RS07570	COG0180	Tryptophanyl-tRNA synthetase
CELAL_RS07575	COG2076	Multidrug Resistance protein
CELAL_RS07585	COG0758	DNA mediated transformation
CELAL_RS07585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CELAL_RS07615	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CELAL_RS07620	COG0756	dUTP diphosphatase activity
CELAL_RS07650	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CELAL_RS07655	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CELAL_RS07660	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CELAL_RS07665	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CELAL_RS07670	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CELAL_RS07675	COG0356	it plays a direct role in the translocation of protons across the membrane
CELAL_RS07710	COG4152	abc transporter atp-binding protein
CELAL_RS07735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CELAL_RS07760	COG4771	TonB-dependent receptor
CELAL_RS07770	COG1309	transcriptional regulator
CELAL_RS07805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CELAL_RS07825	COG0110	maltose O-acetyltransferase activity
CELAL_RS07890	COG4942	peptidase
CELAL_RS07895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CELAL_RS07920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CELAL_RS07925	COG1053	succinate dehydrogenase
CELAL_RS07950	COG0006	proline dipeptidase activity
CELAL_RS07960	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CELAL_RS07965	COG2095	MarC family integral membrane protein
CELAL_RS07970	COG1288	antiporter activity
CELAL_RS07980	COG1114	Component of the transport system for branched-chain amino acids
CELAL_RS07990	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CELAL_RS07995	COG0316	Belongs to the HesB IscA family
CELAL_RS08000	COG0719	Fe-S assembly protein
CELAL_RS08005	COG0396	ATPase activity
CELAL_RS08010	COG0719	Fe-S assembly protein
CELAL_RS08015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CELAL_RS08020	COG2166	iron-sulfur cluster assembly
CELAL_RS08025	COG2151	metal-sulfur cluster biosynthetic enzyme
CELAL_RS08045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CELAL_RS08080	COG1253	flavin adenine dinucleotide binding
CELAL_RS08085	COG0113	porphobilinogen synthase activity
CELAL_RS08090	COG1131	(ABC) transporter
CELAL_RS08115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CELAL_RS08120	COG0408	coproporphyrinogen oxidase activity
CELAL_RS08135	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CELAL_RS08140	COG0569	domain protein
CELAL_RS08145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CELAL_RS08155	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CELAL_RS08175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CELAL_RS08205	COG0464	growth
CELAL_RS08220	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CELAL_RS08240	COG1981	membrane
CELAL_RS08245	COG5000	phosphorelay sensor kinase activity
CELAL_RS08395	COG2963	transposase activity
CELAL_RS08445	COG2963	transposase activity
CELAL_RS08490	COG0456	acetyltransferase
CELAL_RS08495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CELAL_RS08500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CELAL_RS08505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CELAL_RS08515	COG1024	Enoyl-CoA hydratase
CELAL_RS08535	COG0673	inositol 2-dehydrogenase activity
CELAL_RS08540	COG1418	mRNA catabolic process
CELAL_RS08570	COG0793	Belongs to the peptidase S41A family
CELAL_RS08580	COG2095	MarC family integral membrane protein
CELAL_RS08590	COG3275	phosphorelay sensor kinase activity
CELAL_RS08595	COG3279	Response regulator of the LytR AlgR family
CELAL_RS08635	COG2211	Major facilitator Superfamily
CELAL_RS08640	COG0673	inositol 2-dehydrogenase activity
CELAL_RS08670	COG1561	YicC-like family, N-terminal region
CELAL_RS08675	COG0194	GDP metabolic process
CELAL_RS08680	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CELAL_RS08705	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CELAL_RS08715	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CELAL_RS08720	COG0590	tRNA wobble adenosine to inosine editing
CELAL_RS08725	COG1278	Cold shock
CELAL_RS08735	COG0038	chloride channel
CELAL_RS08740	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CELAL_RS08785	COG4771	TonB-dependent receptor
CELAL_RS08790	COG1321	iron dependent repressor
CELAL_RS08790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CELAL_RS08810	COG2363	Small membrane protein
CELAL_RS08815	COG0793	Belongs to the peptidase S41A family
CELAL_RS08815	COG4946	Tricorn protease homolog
CELAL_RS08845	COG0750	zinc metalloprotease
CELAL_RS08855	COG0745	RESPONSE REGULATOR receiver
CELAL_RS08860	COG5002	protein histidine kinase activity
CELAL_RS08860	COG3850	Histidine kinase
CELAL_RS08875	COG1368	sulfuric ester hydrolase activity
CELAL_RS08880	COG1597	lipid kinase activity
CELAL_RS08900	COG4771	TonB-dependent receptor
CELAL_RS08905	COG0702	epimerase
CELAL_RS08930	COG1472	Belongs to the glycosyl hydrolase 3 family
CELAL_RS08935	COG0693	protein deglycase activity
CELAL_RS08955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CELAL_RS08980	COG0783	Belongs to the Dps family
CELAL_RS08985	COG3292	Two component regulator propeller
CELAL_RS08985	COG0745	RESPONSE REGULATOR receiver
CELAL_RS08985	COG2205	protein histidine kinase activity
CELAL_RS08995	COG4251	negative regulation of phosphorylation
CELAL_RS09030	COG0668	transmembrane transport
CELAL_RS09075	COG1166	arginine decarboxylase activity
CELAL_RS09080	COG0010	Belongs to the arginase family
CELAL_RS09085	COG1899	peptidyl-lysine modification to peptidyl-hypusine
CELAL_RS09095	COG0189	ligase activity
CELAL_RS09095	COG4067	protein conserved in archaea
CELAL_RS09100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CELAL_RS09105	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CELAL_RS09145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CELAL_RS09245	COG0123	including yeast histone deacetylase and acetoin utilization protein
CELAL_RS09255	COG1528	Iron-storage protein
CELAL_RS09260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CELAL_RS09260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CELAL_RS09275	COG0792	nuclease activity
CELAL_RS09290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CELAL_RS09310	COG1201	RNA secondary structure unwinding
CELAL_RS09315	COG1793	dna ligase
CELAL_RS09330	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CELAL_RS09340	COG0527	aspartate kinase activity
CELAL_RS09360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CELAL_RS09370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CELAL_RS09370	COG3153	acetyltransferase
CELAL_RS09375	COG2239	Acts as a magnesium transporter
CELAL_RS09380	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CELAL_RS09395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CELAL_RS09405	COG0196	riboflavin kinase activity
CELAL_RS09420	COG0193	aminoacyl-tRNA hydrolase activity
CELAL_RS09425	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CELAL_RS09430	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CELAL_RS09440	COG0671	phosphoesterase, PA-phosphatase related
CELAL_RS09445	COG5002	protein histidine kinase activity
CELAL_RS09455	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CELAL_RS09470	COG1960	acyl-CoA dehydrogenase activity
CELAL_RS09475	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CELAL_RS09485	COG4206	TonB-dependent receptor
CELAL_RS09505	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CELAL_RS09515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CELAL_RS09520	COG0228	four-way junction DNA binding
CELAL_RS09580	COG0784	Response regulator, receiver
CELAL_RS09585	COG4565	transcriptional regulatory protein
CELAL_RS09590	COG2201	protein-glutamate methylesterase activity
CELAL_RS09600	COG1648	precorrin-2 dehydrogenase activity
CELAL_RS09600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CELAL_RS09605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CELAL_RS09630	COG0348	domain, Protein
CELAL_RS09645	COG3278	Belongs to the heme-copper respiratory oxidase family
CELAL_RS09655	COG2217	Heavy metal translocating P-type atpase
CELAL_RS09660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CELAL_RS09670	COG1252	NADH dehydrogenase
CELAL_RS09810	COG0010	Belongs to the arginase family
CELAL_RS09815	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CELAL_RS09820	COG1228	amidohydrolase
CELAL_RS09825	COG2986	histidine ammonia-lyase
CELAL_RS09830	COG0583	DNA-binding transcription factor activity
CELAL_RS09840	COG2839	Protein conserved in bacteria
CELAL_RS09860	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CELAL_RS09865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CELAL_RS09890	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CELAL_RS09920	COG2824	Alkylphosphonate utilization operon protein PhnA
CELAL_RS09940	COG4771	TonB-dependent receptor
CELAL_RS09945	COG0702	epimerase
CELAL_RS09950	COG2186	Transcriptional regulator
CELAL_RS09955	COG2382	esterase
CELAL_RS09960	COG0662	Cupin 2, conserved barrel domain protein
CELAL_RS09960	COG2207	Transcriptional regulator
CELAL_RS09965	COG4771	TonB-dependent receptor
CELAL_RS09970	COG0702	epimerase
CELAL_RS09985	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CELAL_RS10005	COG1519	Transferase
CELAL_RS10015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CELAL_RS10040	COG0508	dehydrogenase complex catalyzes the overall conversion of
CELAL_RS10055	COG0084	hydrolase, TatD family'
CELAL_RS10060	COG0252	asparaginase activity
CELAL_RS10070	COG0811	peptide transport
CELAL_RS10100	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CELAL_RS10105	COG0017	Asparaginyl-tRNA synthetase
CELAL_RS10115	COG0233	cytoplasmic translational termination
CELAL_RS10120	COG0528	UMP kinase activity
CELAL_RS10130	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CELAL_RS10135	COG0052	Belongs to the universal ribosomal protein uS2 family
CELAL_RS10140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CELAL_RS10145	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CELAL_RS10150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CELAL_RS10150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CELAL_RS10155	COG1446	asparaginase
CELAL_RS10190	COG0779	Required for maturation of 30S ribosomal subunits
CELAL_RS10195	COG2251	uridine kinase activity
CELAL_RS10195	COG0195	Participates in both transcription termination and antitermination
CELAL_RS10200	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CELAL_RS10215	COG0437	4 iron, 4 sulfur cluster binding
CELAL_RS10240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CELAL_RS10245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CELAL_RS10260	COG2255	four-way junction helicase activity
CELAL_RS10270	COG1668	transmembrane transport
CELAL_RS10275	COG4555	ABC transporter
CELAL_RS10280	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CELAL_RS10285	COG0280	phosphate acetyltransferase
CELAL_RS10285	COG0281	malic enzyme
CELAL_RS10290	COG0632	four-way junction helicase activity
CELAL_RS10300	COG0509	glycine decarboxylation via glycine cleavage system
CELAL_RS10325	COG0109	protoheme IX farnesyltransferase activity
CELAL_RS10330	COG1845	cytochrome c oxidase, subunit III
CELAL_RS10350	COG1999	signal sequence binding
CELAL_RS10355	COG2322	membrane
CELAL_RS10365	COG0577	efflux transmembrane transporter activity
CELAL_RS10365	COG1136	(ABC) transporter
CELAL_RS10370	COG1136	(ABC) transporter
CELAL_RS10370	COG0577	efflux transmembrane transporter activity
CELAL_RS10375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CELAL_RS10380	COG1136	(ABC) transporter
CELAL_RS10385	COG1136	(ABC) transporter
CELAL_RS10385	COG0577	efflux transmembrane transporter activity
CELAL_RS10390	COG0577	efflux transmembrane transporter activity
CELAL_RS10390	COG1136	(ABC) transporter
CELAL_RS10405	COG1214	PFAM Peptidase M22, glycoprotease
CELAL_RS10410	COG0668	transmembrane transport
CELAL_RS10420	COG0316	Belongs to the HesB IscA family
CELAL_RS10420	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CELAL_RS10435	COG3275	phosphorelay sensor kinase activity
CELAL_RS10440	COG3279	Response regulator of the LytR AlgR family
CELAL_RS10445	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CELAL_RS10450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CELAL_RS10470	COG2949	membrane
CELAL_RS10490	COG0189	ligase activity
CELAL_RS10495	COG0671	phosphoesterase, PA-phosphatase related
CELAL_RS10500	COG0671	phosphoesterase, PA-phosphatase related
CELAL_RS10515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CELAL_RS10525	COG1428	Deoxynucleoside kinase
CELAL_RS10530	COG0616	signal peptide processing
CELAL_RS10560	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CELAL_RS10565	COG0740	serine-type endopeptidase activity
CELAL_RS10570	COG0544	peptidyl-prolyl cis-trans isomerase activity
CELAL_RS10580	COG0596	Alpha beta hydrolase
CELAL_RS10585	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CELAL_RS10595	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CELAL_RS10605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CELAL_RS10610	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CELAL_RS10625	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CELAL_RS10630	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CELAL_RS10665	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CELAL_RS10670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CELAL_RS10680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CELAL_RS10685	COG2086	electron transfer activity
CELAL_RS10690	COG0508	dehydrogenase complex catalyzes the overall conversion of
CELAL_RS10690	COG0022	dehydrogenase e1 component
CELAL_RS10705	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CELAL_RS10715	COG0081	regulation of translation
CELAL_RS10720	COG1428	Deoxynucleoside kinase
CELAL_RS10735	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CELAL_RS10745	COG0460	homoserine dehydrogenase
CELAL_RS10745	COG0527	aspartate kinase activity
CELAL_RS10760	COG1959	2 iron, 2 sulfur cluster binding
CELAL_RS10775	COG0175	sulfate reduction
CELAL_RS10780	COG2895	sulfate adenylyltransferase (ATP) activity
CELAL_RS10785	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CELAL_RS10790	COG1648	precorrin-2 dehydrogenase activity
CELAL_RS10790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CELAL_RS10795	COG0492	ferredoxin-NADP+ reductase activity
CELAL_RS10800	COG1410	methionine synthase
CELAL_RS10800	COG0646	methionine synthase
CELAL_RS10815	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CELAL_RS10840	COG0436	Aminotransferase
CELAL_RS10850	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CELAL_RS10860	COG1162	GTPase activity
CELAL_RS10880	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CELAL_RS10885	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CELAL_RS10925	COG0358	DNA primase activity
CELAL_RS10930	COG2197	response regulator
CELAL_RS10935	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CELAL_RS10955	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CELAL_RS10960	COG2267	carboxylic ester hydrolase activity
CELAL_RS10965	COG2001	Belongs to the MraZ family
CELAL_RS10970	COG0275	rRNA processing
CELAL_RS10980	COG0768	penicillin binding
CELAL_RS10985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CELAL_RS10990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CELAL_RS10995	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CELAL_RS11005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CELAL_RS11010	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CELAL_RS11025	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CELAL_RS11030	COG1610	YqeY-like protein
CELAL_RS11035	COG2827	Endonuclease containing a URI domain
CELAL_RS11040	COG2827	Endonuclease containing a URI domain
CELAL_RS11070	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CELAL_RS11085	COG2197	response regulator
CELAL_RS11095	COG0492	ferredoxin-NADP+ reductase activity
CELAL_RS11100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CELAL_RS11110	COG4628	conserved protein (DUF2132)
CELAL_RS11115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CELAL_RS11140	COG1185	polyribonucleotide nucleotidyltransferase activity
CELAL_RS11145	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CELAL_RS11150	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CELAL_RS11155	COG0191	fructose-bisphosphate aldolase activity
CELAL_RS11165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CELAL_RS11175	COG2226	methyltransferase
CELAL_RS11180	COG0569	domain protein
CELAL_RS11185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CELAL_RS11190	COG0436	Aminotransferase
CELAL_RS11195	COG3239	Fatty acid desaturase
CELAL_RS11200	COG0357	Ribosomal RNA small subunit methyltransferase G
CELAL_RS11210	COG1012	belongs to the aldehyde dehydrogenase family
CELAL_RS11215	COG2967	ApaG domain
CELAL_RS11225	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CELAL_RS11230	COG1805	sodium ion transport
CELAL_RS11235	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CELAL_RS11240	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CELAL_RS11245	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CELAL_RS11260	COG1477	protein flavinylation
CELAL_RS11275	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CELAL_RS11295	COG1876	peptidase activity
CELAL_RS11300	COG2153	protein acetylation
CELAL_RS11325	COG3340	Belongs to the peptidase S51 family
CELAL_RS11360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CELAL_RS11365	COG0671	phosphoesterase, PA-phosphatase related
CELAL_RS11380	COG3844	kynureninase activity
CELAL_RS11405	COG0740	serine-type endopeptidase activity
CELAL_RS11410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CELAL_RS11425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CELAL_RS11430	COG1663	tetraacyldisaccharide 4'-kinase activity
CELAL_RS11440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CELAL_RS11445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CELAL_RS11465	COG1595	DNA-templated transcription, initiation
CELAL_RS11470	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CELAL_RS11475	COG0436	Aminotransferase
CELAL_RS11490	COG0525	valine-tRNA ligase activity
CELAL_RS11530	COG0688	phosphatidylethanolamine metabolic process
CELAL_RS11535	COG0575	Belongs to the CDS family
CELAL_RS11545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CELAL_RS11550	COG0799	negative regulation of ribosome biogenesis
CELAL_RS11565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CELAL_RS11580	COG2201	protein-glutamate methylesterase activity
CELAL_RS11590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CELAL_RS11595	COG1181	Belongs to the D-alanine--D-alanine ligase family
CELAL_RS11600	COG2815	serine threonine protein kinase
CELAL_RS11600	COG0515	serine threonine protein kinase
CELAL_RS11605	COG0564	pseudouridine synthase activity
CELAL_RS11610	COG3022	response to hydroperoxide
CELAL_RS11615	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CELAL_RS11655	COG0159	tryptophan synthase activity
CELAL_RS11660	COG0133	tryptophan synthase activity
CELAL_RS11665	COG0135	phosphoribosylanthranilate isomerase activity
CELAL_RS11670	COG0134	indole-3-glycerol-phosphate synthase activity
CELAL_RS11675	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CELAL_RS11680	COG0512	Glutamine amidotransferase of anthranilate synthase
CELAL_RS11685	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CELAL_RS11695	COG0778	Nitroreductase
CELAL_RS11700	COG1846	Transcriptional regulator
CELAL_RS11715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CELAL_RS11735	COG1115	amino acid carrier protein
CELAL_RS11745	COG1960	acyl-CoA dehydrogenase activity
CELAL_RS11750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CELAL_RS11755	COG4974	Belongs to the 'phage' integrase family
CELAL_RS11800	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CELAL_RS11805	COG0081	regulation of translation
CELAL_RS11810	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CELAL_RS11815	COG0222	ribosome binding
CELAL_RS11820	COG0085	RNA polymerase activity
CELAL_RS11825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CELAL_RS11835	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CELAL_RS11890	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CELAL_RS11900	COG1482	cell wall glycoprotein biosynthetic process
CELAL_RS11920	COG0561	phosphatase activity
CELAL_RS11930	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CELAL_RS11960	COG2258	MOSC domain
CELAL_RS11995	COG0326	Molecular chaperone. Has ATPase activity
CELAL_RS12010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CELAL_RS12035	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CELAL_RS12040	COG0508	dehydrogenase complex catalyzes the overall conversion of
CELAL_RS12045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CELAL_RS12065	COG1546	Belongs to the CinA family
CELAL_RS12065	COG1058	Belongs to the CinA family
CELAL_RS12070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CELAL_RS12075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CELAL_RS12080	COG0552	protein localization to endoplasmic reticulum
CELAL_RS12085	COG0154	amidase activity
CELAL_RS12090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELAL_RS12125	COG0714	Associated with various cellular activities
CELAL_RS12145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CELAL_RS12185	COG2115	Belongs to the xylose isomerase family
CELAL_RS12190	COG2814	Major facilitator Superfamily
CELAL_RS12190	COG0477	Major facilitator Superfamily
CELAL_RS12195	COG0673	inositol 2-dehydrogenase activity
CELAL_RS12200	COG1917	Cupin 2, conserved barrel domain protein
CELAL_RS12200	COG2207	Transcriptional regulator
CELAL_RS12240	COG4771	TonB-dependent receptor
CELAL_RS12250	COG3119	arylsulfatase activity
CELAL_RS12270	COG3119	arylsulfatase activity
CELAL_RS12295	COG3119	arylsulfatase activity
CELAL_RS12325	COG3119	arylsulfatase activity
CELAL_RS12335	COG3119	arylsulfatase activity
CELAL_RS12345	COG3119	arylsulfatase activity
CELAL_RS12360	COG0702	epimerase
CELAL_RS12365	COG4771	TonB-dependent receptor
CELAL_RS12370	COG3119	arylsulfatase activity
CELAL_RS12370	COG3408	Glycogen debranching enzyme
CELAL_RS12375	COG0300	oxidoreductase activity
CELAL_RS12395	COG3119	arylsulfatase activity
CELAL_RS12400	COG3401	FG-GAP repeat protein
CELAL_RS12410	COG3119	arylsulfatase activity
CELAL_RS12415	COG3250	beta-galactosidase activity
CELAL_RS12420	COG3119	arylsulfatase activity
CELAL_RS12430	COG3250	beta-galactosidase activity
CELAL_RS12435	COG3119	arylsulfatase activity
CELAL_RS12440	COG3292	Two component regulator propeller
CELAL_RS12440	COG2205	protein histidine kinase activity
CELAL_RS12440	COG0745	RESPONSE REGULATOR receiver
CELAL_RS12445	COG2271	Major facilitator Superfamily
CELAL_RS12455	COG3386	PFAM SMP-30 Gluconolaconase
CELAL_RS12460	COG1063	alcohol dehydrogenase
CELAL_RS12465	COG2721	sulfolactate sulfo-lyase activity
CELAL_RS12470	COG0246	Mannitol dehydrogenase
CELAL_RS12475	COG3618	amidohydrolase
CELAL_RS12485	COG0738	Major facilitator superfamily
CELAL_RS12490	COG3254	rhamnose metabolic process
CELAL_RS12505	COG4948	Mandelate Racemase Muconate Lactonizing
CELAL_RS12510	COG1012	belongs to the aldehyde dehydrogenase family
CELAL_RS12515	COG3119	arylsulfatase activity
CELAL_RS12520	COG1028	Short-chain dehydrogenase reductase Sdr
CELAL_RS12525	COG1063	alcohol dehydrogenase
CELAL_RS12530	COG1414	Transcriptional regulator
CELAL_RS12550	COG4771	TonB-dependent receptor
CELAL_RS12555	COG0702	epimerase
CELAL_RS12570	COG1629	transport
CELAL_RS12570	COG4206	TonB-dependent receptor
CELAL_RS12575	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CELAL_RS12600	COG0366	Alpha amylase catalytic
CELAL_RS12615	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CELAL_RS12620	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CELAL_RS12640	COG0343	queuine tRNA-ribosyltransferase activity
CELAL_RS12655	COG0825	malonyl-CoA metabolic process
CELAL_RS12660	COG0305	Participates in initiation and elongation during chromosome replication
CELAL_RS12780	COG1280	lysine exporter protein (LysE YggA)
CELAL_RS12785	COG0583	DNA-binding transcription factor activity
CELAL_RS12840	COG0561	phosphatase activity
CELAL_RS12845	COG0432	Pfam Uncharacterised protein family UPF0047
CELAL_RS12855	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CELAL_RS12860	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CELAL_RS12865	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CELAL_RS12870	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CELAL_RS12880	COG1879	ABC-type sugar transport system periplasmic component
CELAL_RS12890	COG1172	Belongs to the binding-protein-dependent transport system permease family
CELAL_RS12895	COG0246	Mannitol dehydrogenase
CELAL_RS12900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CELAL_RS12905	COG0246	Mannitol dehydrogenase
CELAL_RS12975	COG1272	protein, Hemolysin III
CELAL_RS12990	COG0116	Belongs to the methyltransferase superfamily
CELAL_RS13010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CELAL_RS13015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CELAL_RS13055	COG1104	cysteine desulfurase activity
CELAL_RS13070	COG0739	heme binding
CELAL_RS13085	COG1418	mRNA catabolic process
CELAL_RS13090	COG0612	Peptidase, M16
CELAL_RS13100	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CELAL_RS13115	COG0076	glutamate decarboxylase activity
CELAL_RS13125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CELAL_RS13125	COG0519	Catalyzes the synthesis of GMP from XMP
CELAL_RS13130	COG1388	LysM domain
CELAL_RS13130	COG3942	CHAP domain
CELAL_RS13150	COG3530	Putative quorum-sensing-regulated virulence factor
CELAL_RS13155	COG0504	CTP synthase activity
CELAL_RS13160	COG0706	membrane insertase activity
CELAL_RS13165	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CELAL_RS13170	COG0482	sulfurtransferase activity
CELAL_RS13180	COG3956	TIGRFAM MazG family protein
CELAL_RS13185	COG0534	Mate efflux family protein
CELAL_RS13195	COG0671	phosphoesterase, PA-phosphatase related
CELAL_RS13210	COG0463	Glycosyl transferase, family 2
CELAL_RS13220	COG1764	response to oxidative stress
CELAL_RS13230	COG1595	DNA-templated transcription, initiation
CELAL_RS13245	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CELAL_RS13285	COG0653	protein targeting
CELAL_RS13305	COG0488	(ABC) transporter
CELAL_RS13320	COG1137	ATPase activity
CELAL_RS13330	COG0805	protein transport
CELAL_RS13335	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CELAL_RS13335	COG0517	IMP dehydrogenase activity
CELAL_RS13340	COG0514	ATP-dependent DNA helicase (RecQ)
CELAL_RS13350	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CELAL_RS13360	COG0352	thiamine-phosphate diphosphorylase activity
CELAL_RS13365	COG2022	thiamine diphosphate biosynthetic process
CELAL_RS13370	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CELAL_RS13375	COG1619	proteins homologs of microcin C7 resistance protein MccF
CELAL_RS13380	COG0656	L-ascorbic acid biosynthetic process
CELAL_RS13460	COG1028	Short-chain dehydrogenase reductase Sdr
CELAL_RS13485	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CELAL_RS13490	COG0492	ferredoxin-NADP+ reductase activity
CELAL_RS13505	COG1629	transport
CELAL_RS13515	COG0156	8-amino-7-oxononanoate synthase activity
CELAL_RS13520	COG4948	Mandelate Racemase Muconate Lactonizing
CELAL_RS13560	COG0494	nUDIX hydrolase
CELAL_RS13580	COG0783	Belongs to the Dps family
CELAL_RS13590	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CELAL_RS13595	COG2808	Putative FMN-binding domain
CELAL_RS13600	COG4251	negative regulation of phosphorylation
CELAL_RS13615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CELAL_RS13635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CELAL_RS13655	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CELAL_RS13660	COG0735	belongs to the Fur family
CELAL_RS13665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CELAL_RS13670	COG0501	Belongs to the peptidase M48B family
CELAL_RS13675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CELAL_RS13700	COG0746	molybdenum cofactor guanylyltransferase activity
CELAL_RS13700	COG0315	cyclic pyranopterin monophosphate synthase activity
CELAL_RS13705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CELAL_RS13715	COG0303	'Molybdopterin
CELAL_RS13725	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CELAL_RS13735	COG2195	Cleaves the N-terminal amino acid of tripeptides
CELAL_RS13740	COG0501	Belongs to the peptidase M48B family
CELAL_RS13745	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CELAL_RS13750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CELAL_RS13760	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CELAL_RS13770	COG0105	UTP biosynthetic process
CELAL_RS13780	COG0494	nUDIX hydrolase
CELAL_RS13795	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CELAL_RS13805	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CELAL_RS13815	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CELAL_RS13845	COG0681	Belongs to the peptidase S26 family
CELAL_RS13850	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CELAL_RS13860	COG1475	DNA binding
CELAL_RS13865	COG1192	Involved in chromosome partitioning
CELAL_RS13870	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CELAL_RS13870	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CELAL_RS13875	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CELAL_RS13885	COG0572	uridine kinase
CELAL_RS13890	COG2814	Major facilitator Superfamily
CELAL_RS13920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CELAL_RS13925	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CELAL_RS13930	COG1472	Belongs to the glycosyl hydrolase 3 family
CELAL_RS13935	COG2211	Major facilitator Superfamily
CELAL_RS13940	COG1649	PFAM Uncharacterised BCR, COG1649
CELAL_RS13955	COG0363	glucosamine-6-phosphate deaminase activity
CELAL_RS13960	COG1349	DNA-binding transcription factor activity
CELAL_RS13965	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CELAL_RS14045	COG2885	chlorophyll binding
CELAL_RS14055	COG4774	siderophore transport
CELAL_RS14080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CELAL_RS14085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CELAL_RS14095	COG1914	H( )-stimulated, divalent metal cation uptake system
CELAL_RS14100	COG3279	Response regulator of the LytR AlgR family
CELAL_RS14110	COG2354	Protein conserved in bacteria
CELAL_RS14115	COG2267	carboxylic ester hydrolase activity
CELAL_RS14120	COG1028	Short-chain dehydrogenase reductase Sdr
CELAL_RS14145	COG2720	vancomycin resistance protein
CELAL_RS14225	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CELAL_RS14230	COG0714	Associated with various cellular activities
CELAL_RS14265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CELAL_RS14290	COG1473	amidohydrolase
CELAL_RS14305	COG1252	NADH dehydrogenase
CELAL_RS14315	COG4974	Belongs to the 'phage' integrase family
CELAL_RS14330	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CELAL_RS14350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CELAL_RS14365	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CELAL_RS14405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CELAL_RS14410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CELAL_RS14425	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CELAL_RS14430	COG0540	Belongs to the ATCase OTCase family
CELAL_RS14445	COG1234	tRNA 3'-trailer cleavage
CELAL_RS14455	COG0259	pyridoxamine-phosphate oxidase activity
CELAL_RS14465	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CELAL_RS14480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CELAL_RS14490	COG0742	ribosomal rna small subunit methyltransferase
CELAL_RS14505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CELAL_RS14515	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CELAL_RS14530	COG1454	alcohol dehydrogenase
CELAL_RS14545	COG0217	transcriptional regulatory protein
CELAL_RS14550	COG2154	pterin-4-alpha-carbinolamine dehydratase
CELAL_RS14560	COG2066	Belongs to the glutaminase family
CELAL_RS14565	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CELAL_RS14580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CELAL_RS14595	COG0083	homoserine kinase activity
CELAL_RS14605	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CELAL_RS14630	COG0542	response to heat
CELAL_RS14635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CELAL_RS14660	COG0183	Belongs to the thiolase family
CELAL_RS14690	COG0469	pyruvate kinase activity
CELAL_RS14695	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CELAL_RS14705	COG0745	RESPONSE REGULATOR receiver
CELAL_RS14725	COG1012	belongs to the aldehyde dehydrogenase family
CELAL_RS14730	COG0783	Belongs to the Dps family
CELAL_RS14740	COG0028	Belongs to the TPP enzyme family
CELAL_RS14745	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CELAL_RS14745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CELAL_RS14750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CELAL_RS14755	COG4716	Myosin-crossreactive antigen
CELAL_RS14770	COG4716	Myosin-crossreactive antigen
CELAL_RS14780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CELAL_RS14800	COG0837	glucose binding
CELAL_RS14805	COG1830	Aldolase
CELAL_RS14815	COG0588	phosphoglycerate mutase activity
CELAL_RS14820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CELAL_RS14825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CELAL_RS14825	COG0574	Belongs to the PEP-utilizing enzyme family
CELAL_RS14830	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CELAL_RS14850	COG0356	it plays a direct role in the translocation of protons across the membrane
CELAL_RS14860	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CELAL_RS14865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CELAL_RS14870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CELAL_RS14880	COG0148	phosphopyruvate hydratase activity
CELAL_RS14890	COG1127	ABC transporter
CELAL_RS14895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CELAL_RS14900	COG0038	chloride channel
CELAL_RS15005	COG0156	8-amino-7-oxononanoate synthase activity
CELAL_RS15010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CELAL_RS15025	COG0538	isocitrate dehydrogenase activity
CELAL_RS15030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CELAL_RS15050	COG0753	catalase activity
CELAL_RS15055	COG0583	DNA-binding transcription factor activity
CELAL_RS15065	COG2095	MarC family integral membrane protein
CELAL_RS15095	COG0633	Ferredoxin
CELAL_RS15110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CELAL_RS15115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CELAL_RS15130	COG0589	response to stress
CELAL_RS15145	COG0589	response to stress
CELAL_RS15160	COG0745	RESPONSE REGULATOR receiver
CELAL_RS15165	COG2202	Pas domain
CELAL_RS15165	COG1366	Belongs to the anti-sigma-factor antagonist family
CELAL_RS15175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CELAL_RS15195	COG0708	Exodeoxyribonuclease III
CELAL_RS15200	COG3174	membrane
CELAL_RS15210	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CELAL_RS15215	COG0280	phosphate acetyltransferase
CELAL_RS15215	COG0857	belongs to the CobB CobQ family
CELAL_RS15230	COG0577	efflux transmembrane transporter activity
CELAL_RS15230	COG1136	(ABC) transporter
CELAL_RS15235	COG1136	(ABC) transporter
CELAL_RS15245	COG0789	Transcriptional regulator
CELAL_RS15250	COG0484	heat shock protein binding
CELAL_RS15255	COG0745	RESPONSE REGULATOR receiver
CELAL_RS15290	COG3279	Response regulator of the LytR AlgR family
CELAL_RS15300	COG5002	protein histidine kinase activity
CELAL_RS15310	COG4251	negative regulation of phosphorylation
CELAL_RS15320	COG0784	Response regulator, receiver
CELAL_RS15360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CELAL_RS15435	COG0604	alcohol dehydrogenase
CELAL_RS15455	COG0583	DNA-binding transcription factor activity
CELAL_RS15460	COG0800	Aldolase
CELAL_RS15485	COG2755	lipolytic protein G-D-S-L family
CELAL_RS15485	COG0657	acetylesterase activity
CELAL_RS15495	COG0628	permease
CELAL_RS15520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CELAL_RS15530	COG0205	6-phosphofructokinase activity
CELAL_RS15545	COG0251	oxidation-reduction process
CELAL_RS15565	COG0247	lactate metabolic process
CELAL_RS15565	COG2181	nitrate reductase activity
CELAL_RS15570	COG2181	nitrate reductase activity
CELAL_RS15570	COG0247	lactate metabolic process
CELAL_RS15585	COG0438	transferase activity, transferring glycosyl groups
CELAL_RS15650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CELAL_RS15655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CELAL_RS15705	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CELAL_RS15725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CELAL_RS15730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CELAL_RS15740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CELAL_RS15745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CELAL_RS15800	COG4152	abc transporter atp-binding protein
CELAL_RS15820	COG1858	cytochrome C peroxidase
CELAL_RS15845	COG2885	chlorophyll binding
CELAL_RS15910	COG1966	Carbon starvation protein
CELAL_RS15925	COG1196	nuclear chromosome segregation
CELAL_RS15935	COG0563	adenylate kinase activity
CELAL_RS16075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CELAL_RS16105	COG3279	Response regulator of the LytR AlgR family
CELAL_RS16110	COG0745	RESPONSE REGULATOR receiver
CELAL_RS16110	COG2972	Histidine kinase
CELAL_RS16120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CELAL_RS16160	COG0322	excinuclease ABC activity
CELAL_RS16165	COG0210	DNA helicase
CELAL_RS16180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CELAL_RS16195	COG0592	DNA-directed DNA polymerase activity
CELAL_RS16205	COG1702	phosphate starvation-inducible protein PhoH
CELAL_RS16210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CELAL_RS16240	COG2072	flavoprotein involved in K transport
CELAL_RS16340	COG1629	transport
CELAL_RS16350	COG4771	TonB-dependent receptor
CELAL_RS16355	COG0702	epimerase
CELAL_RS16395	COG4771	TonB-dependent receptor
CELAL_RS16440	COG3344	reverse transcriptase
CELAL_RS16475	COG2963	transposase activity
CELAL_RS16510	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CELAL_RS16635	COG4974	Belongs to the 'phage' integrase family
CELAL_RS16660	COG1678	Uncharacterized ACR, COG1678
CELAL_RS16670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CELAL_RS16675	COG0514	ATP-dependent DNA helicase (RecQ)
CELAL_RS16695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CELAL_RS16740	COG4221	oxidoreductase activity
CELAL_RS16750	COG2202	Pas domain
CELAL_RS16750	COG1366	Belongs to the anti-sigma-factor antagonist family
CELAL_RS16780	COG2153	protein acetylation
CELAL_RS16790	COG0415	Belongs to the DNA photolyase family
CELAL_RS16830	COG0424	maF-like protein
CELAL_RS16845	COG1333	cytochrome c biogenesis protein
CELAL_RS16845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CELAL_RS16850	COG0626	cystathionine gamma-synthase activity
CELAL_RS16855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CELAL_RS16875	COG0473	3-isopropylmalate dehydrogenase activity
CELAL_RS16880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CELAL_RS16900	COG0564	pseudouridine synthase activity
CELAL_RS16905	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CELAL_RS16910	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CELAL_RS16930	COG1760	l-serine dehydratase
CELAL_RS16945	COG0443	Heat shock 70 kDa protein
CELAL_RS16975	COG2050	protein possibly involved in aromatic compounds catabolism
CELAL_RS16985	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CELAL_RS16995	COG2996	Protein conserved in bacteria
CELAL_RS17005	COG1575	Belongs to the MenA family. Type 1 subfamily
CELAL_RS17010	COG0784	Response regulator, receiver
CELAL_RS17020	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CELAL_RS17025	COG4221	oxidoreductase activity
CELAL_RS17030	COG4948	Mandelate Racemase Muconate Lactonizing
CELAL_RS17050	COG2304	oxidoreductase activity
CELAL_RS17060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CELAL_RS17075	COG0488	(ABC) transporter
CELAL_RS17080	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CELAL_RS17115	COG1393	Belongs to the ArsC family
CELAL_RS17120	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CELAL_RS17135	COG2308	Evidence 4 Homologs of previously reported genes of
CELAL_RS17165	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CELAL_RS17170	COG1770	oligopeptidase
CELAL_RS17180	COG0156	8-amino-7-oxononanoate synthase activity
CELAL_RS17220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CELAL_RS17225	COG1595	DNA-templated transcription, initiation
CELAL_RS17230	COG1595	DNA-templated transcription, initiation
CELAL_RS17235	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CELAL_RS17240	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CELAL_RS17245	COG4974	Belongs to the 'phage' integrase family
CELAL_RS17285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CELAL_RS17310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CELAL_RS17345	COG1858	cytochrome C peroxidase
CELAL_RS17365	COG0302	gtp cyclohydrolase
CELAL_RS17410	COG3275	phosphorelay sensor kinase activity
CELAL_RS17415	COG3279	Response regulator of the LytR AlgR family
CELAL_RS17425	COG3046	protein related to deoxyribodipyrimidine photolyase
CELAL_RS17435	COG0415	Belongs to the DNA photolyase family
CELAL_RS17485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CELAL_RS17520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CELAL_RS17535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CELAL_RS17540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CELAL_RS17575	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CELAL_RS17580	COG2217	Heavy metal translocating P-type atpase
CELAL_RS17620	COG2217	Heavy metal translocating P-type atpase
CELAL_RS17650	COG0386	Belongs to the glutathione peroxidase family
CELAL_RS17680	COG0437	4 iron, 4 sulfur cluster binding
CELAL_RS17695	COG0243	molybdopterin cofactor binding
CELAL_RS17730	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CELAL_RS17740	COG0363	glucosamine-6-phosphate deaminase activity
CELAL_RS17770	COG0596	Alpha beta hydrolase
CELAL_RS17775	COG2205	protein histidine kinase activity
CELAL_RS17800	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CELAL_RS17810	COG1028	Short-chain dehydrogenase reductase Sdr
CELAL_RS17815	COG3279	Response regulator of the LytR AlgR family
CELAL_RS17830	COG0038	chloride channel
CELAL_RS17870	COG3250	beta-galactosidase activity
CELAL_RS17875	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CELAL_RS17885	COG1629	transport
CELAL_RS17890	COG0745	RESPONSE REGULATOR receiver
CELAL_RS17890	COG3292	Two component regulator propeller
CELAL_RS17890	COG2205	protein histidine kinase activity
CELAL_RS17900	COG2814	Major facilitator Superfamily
CELAL_RS17920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CELAL_RS17985	COG0732	type I restriction modification DNA specificity domain
CELAL_RS18025	COG0778	Nitroreductase
CELAL_RS18030	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CELAL_RS18035	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CELAL_RS18035	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CELAL_RS18050	COG1674	ftsk spoiiie
CELAL_RS18055	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CELAL_RS18060	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CELAL_RS18070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CELAL_RS18075	COG0450	alkyl hydroperoxide reductase
CELAL_RS18080	COG1757	Na H antiporter
CELAL_RS18085	COG0626	cystathionine gamma-synthase activity
CELAL_RS18090	COG1522	sequence-specific DNA binding
CELAL_RS18095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CELAL_RS18100	COG0667	Aldo Keto reductase
CELAL_RS18120	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CELAL_RS18125	COG0037	tRNA processing
CELAL_RS18130	COG4232	protein-disulfide reductase activity
CELAL_RS18145	COG0784	Response regulator, receiver
CELAL_RS18145	COG0643	Histidine kinase
CELAL_RS18145	COG2198	Histidine kinase
CELAL_RS18175	COG0606	chelatase, subunit chli
CELAL_RS18205	COG1914	H( )-stimulated, divalent metal cation uptake system
CELAL_RS18215	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CELAL_RS18220	COG1984	allophanate hydrolase subunit 2
CELAL_RS18225	COG1012	belongs to the aldehyde dehydrogenase family
CELAL_RS18230	COG0129	dihydroxy-acid dehydratase activity
CELAL_RS18235	COG0028	Belongs to the TPP enzyme family
CELAL_RS18240	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CELAL_RS18245	COG0440	acetolactate synthase activity
CELAL_RS18250	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CELAL_RS18260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CELAL_RS18265	COG1012	belongs to the aldehyde dehydrogenase family
CELAL_RS18280	COG2814	Major facilitator Superfamily
CELAL_RS18290	COG0542	response to heat
CELAL_RS18310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CELAL_RS18325	COG4585	Histidine kinase
CELAL_RS18325	COG2203	Gaf domain
CELAL_RS18330	COG3279	Response regulator of the LytR AlgR family
CELAL_RS18355	COG0300	oxidoreductase activity
CELAL_RS18360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CELAL_RS18370	COG0488	(ABC) transporter
CELAL_RS18375	COG0473	3-isopropylmalate dehydrogenase activity
CELAL_RS18385	COG0066	3-isopropylmalate dehydratase activity
CELAL_RS18395	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CELAL_RS18410	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CELAL_RS18555	COG3209	COG3209 Rhs family protein
CELAL_RS18555	COG4104	PAAR repeat-containing protein
CELAL_RS18600	COG4104	PAAR repeat-containing protein
CELAL_RS18600	COG3209	COG3209 Rhs family protein
CELAL_RS18625	COG0542	response to heat
CELAL_RS18745	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CELAL_RS18750	COG0308	aminopeptidase N
CELAL_RS18785	COG0069	glutamate synthase activity
CELAL_RS18790	COG1473	amidohydrolase
CELAL_RS18805	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CELAL_RS18810	COG0346	lactoylglutathione lyase activity
CELAL_RS18820	COG0009	L-threonylcarbamoyladenylate synthase
CELAL_RS18860	COG1611	Belongs to the LOG family
CELAL_RS18900	COG3123	guanosine phosphorylase activity
CELAL_RS18910	COG0405	Gamma-glutamyltransferase
CELAL_RS18920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CELAL_RS18940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CELAL_RS18950	COG0277	FAD linked oxidase domain protein
CELAL_RS18950	COG0247	lactate metabolic process
CELAL_RS18960	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CELAL_RS18965	COG1301	dicarboxylic acid transport
CELAL_RS18975	COG2267	carboxylic ester hydrolase activity
CELAL_RS18980	COG2453	phosphatase
CELAL_RS18980	COG0671	phosphoesterase, PA-phosphatase related
CELAL_RS18995	COG4589	Belongs to the CDS family
CELAL_RS19000	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CELAL_RS19010	COG1629	transport
CELAL_RS19015	COG3011	Protein conserved in bacteria
CELAL_RS19030	COG0589	response to stress
CELAL_RS19030	COG0475	glutathione-regulated potassium exporter activity
CELAL_RS19050	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CELAL_RS19055	COG2201	protein-glutamate methylesterase activity
CELAL_RS19065	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CELAL_RS19090	COG0022	dehydrogenase e1 component
CELAL_RS19100	COG2885	chlorophyll binding
CELAL_RS19105	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CELAL_RS19110	COG2264	protein methyltransferase activity
CELAL_RS19120	COG1028	Short-chain dehydrogenase reductase Sdr
CELAL_RS19125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CELAL_RS19135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CELAL_RS19165	COG1629	transport
CELAL_RS19165	COG4206	TonB-dependent receptor
CELAL_RS19170	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CELAL_RS19175	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CELAL_RS19185	COG0590	tRNA wobble adenosine to inosine editing
CELAL_RS19195	COG0668	transmembrane transport
CELAL_RS19215	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CELAL_RS19225	COG0446	pyridine nucleotide-disulphide oxidoreductase
CELAL_RS19225	COG1902	pentaerythritol trinitrate reductase activity
CELAL_RS19255	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CELAL_RS19275	COG0745	RESPONSE REGULATOR receiver
CELAL_RS19275	COG3292	Two component regulator propeller
CELAL_RS19275	COG2205	protein histidine kinase activity
CELAL_RS19325	COG4251	negative regulation of phosphorylation
CELAL_RS19330	COG2205	protein histidine kinase activity
CELAL_RS19335	COG1136	(ABC) transporter
CELAL_RS19335	COG0577	efflux transmembrane transporter activity
CELAL_RS19340	COG4181	ATPase activity
CELAL_RS19355	COG1028	Short-chain dehydrogenase reductase Sdr
CELAL_RS19370	COG0596	Alpha beta hydrolase
CELAL_RS19375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CELAL_RS19395	COG2816	NAD+ diphosphatase activity
CELAL_RS19405	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CELAL_RS19415	COG2132	Multicopper oxidase
CELAL_RS19440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CELAL_RS19445	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CELAL_RS19450	COG1278	Cold shock
CELAL_RS19455	COG0668	transmembrane transport
CELAL_RS19480	COG2308	Evidence 4 Homologs of previously reported genes of
CELAL_RS19505	COG2307	Protein conserved in bacteria
CELAL_RS19505	COG2308	Evidence 4 Homologs of previously reported genes of
CELAL_RS19555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CELAL_RS19570	COG2169	Transcriptional regulator
CELAL_RS19570	COG1917	Cupin 2, conserved barrel domain protein
CELAL_RS19615	COG1131	(ABC) transporter
CELAL_RS19620	COG1131	(ABC) transporter
CELAL_RS19625	COG0842	Transport permease protein
CELAL_RS19630	COG1129	ABC transporter
CELAL_RS19630	COG0842	Transport permease protein
CELAL_RS19640	COG4771	TonB-dependent receptor
CELAL_RS19655	COG2195	Cleaves the N-terminal amino acid of tripeptides
CELAL_RS19715	COG0492	ferredoxin-NADP+ reductase activity
CELAL_RS19725	COG0783	Belongs to the Dps family
CELAL_RS19735	COG0604	alcohol dehydrogenase
CELAL_RS19740	COG0778	Nitroreductase
CELAL_RS19750	COG1012	belongs to the aldehyde dehydrogenase family
CELAL_RS19760	COG4221	oxidoreductase activity
CELAL_RS19765	COG1012	belongs to the aldehyde dehydrogenase family
CELAL_RS19890	COG3279	Response regulator of the LytR AlgR family
CELAL_RS19935	COG0803	Belongs to the bacterial solute-binding protein 9 family
CELAL_RS19940	COG1121	(ABC) transporter
CELAL_RS19945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CELAL_RS19945	COG1321	iron dependent repressor
CELAL_RS19950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CELAL_RS19975	COG3279	Response regulator of the LytR AlgR family
CELAL_RS19980	COG3275	phosphorelay sensor kinase activity
CELAL_RS19985	COG1136	(ABC) transporter
CELAL_RS19985	COG0577	efflux transmembrane transporter activity
CELAL_RS19990	COG1136	(ABC) transporter
CELAL_RS19995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CELAL_RS20215	COG0513	Belongs to the DEAD box helicase family
CELAL_RS20225	COG1858	cytochrome C peroxidase
CELAL_RS20240	COG0339	signal peptide processing
CELAL_RS20250	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CELAL_RS20280	COG2130	NADP-dependent
CELAL_RS20285	COG1979	alcohol dehydrogenase
CELAL_RS20295	COG1902	pentaerythritol trinitrate reductase activity
CELAL_RS20300	COG1187	pseudouridine synthase activity
CELAL_RS20315	COG0484	heat shock protein binding
CELAL_RS20320	COG1047	Peptidyl-prolyl cis-trans
CELAL_RS20345	COG2972	Histidine kinase
CELAL_RS20350	COG3279	Response regulator of the LytR AlgR family
CELAL_RS20355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CELAL_RS20365	COG0513	Belongs to the DEAD box helicase family
CELAL_RS20370	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CELAL_RS20375	COG0514	ATP-dependent DNA helicase (RecQ)
CELAL_RS20385	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CELAL_RS20390	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CELAL_RS20440	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CELAL_RS20450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CELAL_RS20460	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CELAL_RS20465	COG1215	transferase activity, transferring glycosyl groups
CELAL_RS20475	COG0745	RESPONSE REGULATOR receiver
CELAL_RS20485	COG1607	acyl-coa hydrolase
CELAL_RS20500	COG1045	serine acetyltransferase
CELAL_RS20510	COG0598	Magnesium transport protein CorA
CELAL_RS20515	COG0101	tRNA pseudouridine synthase activity
CELAL_RS20525	COG0612	Peptidase, M16
CELAL_RS20535	COG0745	RESPONSE REGULATOR receiver
CELAL_RS20540	COG5002	protein histidine kinase activity
CELAL_RS20540	COG3850	Histidine kinase
CELAL_RS20565	COG0583	DNA-binding transcription factor activity
CELAL_RS20570	COG2855	membrane
CELAL_RS20580	COG0140	phosphoribosyl-ATP diphosphatase activity
CELAL_RS20580	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CELAL_RS20585	COG0107	imidazoleglycerol-phosphate synthase activity
CELAL_RS20590	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CELAL_RS20600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CELAL_RS20605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CELAL_RS20605	COG0131	Imidazoleglycerol-phosphate dehydratase
CELAL_RS20610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CELAL_RS20615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CELAL_RS20625	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CELAL_RS20640	COG1028	Short-chain dehydrogenase reductase Sdr
CELAL_RS20645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CELAL_RS20650	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CELAL_RS20655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CELAL_RS20660	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CELAL_RS20665	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CELAL_RS20665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CELAL_RS20670	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CELAL_RS20675	COG1078	dGTPase activity
CELAL_RS20680	COG2204	response regulator
CELAL_RS20720	COG0686	Belongs to the AlaDH PNT family
CELAL_RS20730	COG0506	proline dehydrogenase activity
CELAL_RS20735	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CELAL_RS20750	COG1522	sequence-specific DNA binding
CELAL_RS20775	COG1970	mechanosensitive ion channel activity
CELAL_RS20795	COG0012	GTP binding
CELAL_RS20800	COG1595	DNA-templated transcription, initiation
CELAL_RS20810	COG4771	TonB-dependent receptor
CELAL_RS20815	COG1629	transport
CELAL_RS20820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CELAL_RS20830	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CELAL_RS20835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CELAL_RS20860	COG4771	TonB-dependent receptor
CELAL_RS20865	COG0205	6-phosphofructokinase activity
CELAL_RS20875	COG1609	Transcriptional regulator
CELAL_RS20885	COG2271	Major facilitator Superfamily
CELAL_RS20890	COG2186	Transcriptional regulator
CELAL_RS20910	COG0702	epimerase
CELAL_RS20915	COG4771	TonB-dependent receptor
CELAL_RS20940	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CELAL_RS20960	COG1271	oxidase subunit
CELAL_RS20965	COG1294	oxidase, subunit
CELAL_RS20975	COG2985	domain, Protein
CELAL_RS20985	COG0252	asparaginase activity
CELAL_RS20995	COG2169	Transcriptional regulator
CELAL_RS20995	COG1917	Cupin 2, conserved barrel domain protein
CELAL_RS21000	COG3938	Belongs to the proline racemase family
CELAL_RS21005	COG2234	aminopeptidase activity
CELAL_RS21015	COG2205	protein histidine kinase activity
CELAL_RS21025	COG2205	protein histidine kinase activity
CELAL_RS21050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CELAL_RS21060	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CELAL_RS21065	COG0673	inositol 2-dehydrogenase activity
CELAL_RS21070	COG1250	3-hydroxyacyl-CoA dehydrogenase
CELAL_RS21075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CELAL_RS21080	COG2176	DNA-directed DNA polymerase activity
CELAL_RS21085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CELAL_RS21090	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CELAL_RS21095	COG3265	gluconokinase activity
CELAL_RS21100	COG2610	gluconate transmembrane transporter activity
CELAL_RS21110	COG2610	gluconate transmembrane transporter activity
CELAL_RS21125	COG0237	dephospho-CoA kinase activity
CELAL_RS21140	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CELAL_RS21145	COG0497	DNA recombination
CELAL_RS21170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CELAL_RS21180	COG0737	Belongs to the 5'-nucleotidase family
CELAL_RS21185	COG0737	Belongs to the 5'-nucleotidase family
CELAL_RS21195	COG1278	Cold shock
CELAL_RS21215	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CELAL_RS21220	COG2890	protein-(glutamine-N5) methyltransferase activity
CELAL_RS21225	COG0456	acetyltransferase
CELAL_RS21230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CELAL_RS21230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CELAL_RS21235	COG1011	Hydrolase
CELAL_RS21245	COG1739	Uncharacterized protein family UPF0029
CELAL_RS21265	COG3119	arylsulfatase activity
CELAL_RS21275	COG3119	arylsulfatase activity
CELAL_RS21280	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CELAL_RS21315	COG4191	Histidine kinase
CELAL_RS21350	COG2885	chlorophyll binding
CELAL_RS21385	COG3447	MASE1 domain protein
CELAL_RS21385	COG5001	Diguanylate cyclase
CELAL_RS21385	COG5002	protein histidine kinase activity
CELAL_RS21470	COG4251	negative regulation of phosphorylation
CELAL_RS21480	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CELAL_RS21555	COG0363	glucosamine-6-phosphate deaminase activity
CELAL_RS21575	COG1366	Belongs to the anti-sigma-factor antagonist family
CELAL_RS21650	COG4251	negative regulation of phosphorylation
CELAL_RS21665	COG3209	COG3209 Rhs family protein
CELAL_RS21670	COG0791	NLP P60 protein
CELAL_RS21715	COG3275	phosphorelay sensor kinase activity