locus-tag	class	description
CELLY_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CELLY_RS00010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CELLY_RS00015	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CELLY_RS00025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CELLY_RS00035	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CELLY_RS00060	COG0336	Belongs to the RNA methyltransferase TrmD family
CELLY_RS00070	COG0335	large ribosomal subunit rRNA binding
CELLY_RS00095	COG1418	mRNA catabolic process
CELLY_RS00110	COG0739	heme binding
CELLY_RS00120	COG1104	cysteine desulfurase activity
CELLY_RS00150	COG0514	ATP-dependent DNA helicase (RecQ)
CELLY_RS00155	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CELLY_RS00155	COG0517	IMP dehydrogenase activity
CELLY_RS00160	COG0805	protein transport
CELLY_RS00170	COG1137	ATPase activity
CELLY_RS00175	COG1183	phosphatidylcholine synthase activity
CELLY_RS00185	COG0488	(ABC) transporter
CELLY_RS00210	COG0653	protein targeting
CELLY_RS00255	COG1595	DNA-templated transcription, initiation
CELLY_RS00265	COG1703	isobutyryl-CoA mutase activity
CELLY_RS00270	COG0463	Glycosyl transferase, family 2
CELLY_RS00290	COG0534	Mate efflux family protein
CELLY_RS00295	COG3956	TIGRFAM MazG family protein
CELLY_RS00300	COG4628	conserved protein (DUF2132)
CELLY_RS00305	COG0513	Belongs to the DEAD box helicase family
CELLY_RS00325	COG2204	response regulator
CELLY_RS00330	COG5002	protein histidine kinase activity
CELLY_RS00350	COG2972	Histidine kinase
CELLY_RS00355	COG3279	Response regulator of the LytR AlgR family
CELLY_RS00365	COG0242	peptide deformylase activity
CELLY_RS00370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CELLY_RS00375	COG2171	N-acyltransferase activity
CELLY_RS00395	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CELLY_RS00405	COG0009	L-threonylcarbamoyladenylate synthase
CELLY_RS00410	COG0517	IMP dehydrogenase activity
CELLY_RS00410	COG0617	tRNA 3'-terminal CCA addition
CELLY_RS00410	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CELLY_RS00465	COG1131	(ABC) transporter
CELLY_RS00485	COG0556	nucleotide-excision repair
CELLY_RS00505	COG0045	succinate-CoA ligase (ADP-forming) activity
CELLY_RS00530	COG0798	PFAM Bile acid sodium symporter
CELLY_RS00555	COG0516	GMP reductase activity
CELLY_RS00555	COG0517	IMP dehydrogenase activity
CELLY_RS00605	COG0167	dihydroorotate dehydrogenase activity
CELLY_RS00610	COG2195	Cleaves the N-terminal amino acid of tripeptides
CELLY_RS00620	COG1862	Preprotein translocase
CELLY_RS00630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CELLY_RS00635	COG1132	(ABC) transporter
CELLY_RS00650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CELLY_RS00660	COG2318	DinB family
CELLY_RS00665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CELLY_RS00675	COG2326	polyphosphate kinase activity
CELLY_RS00695	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CELLY_RS00720	COG0668	transmembrane transport
CELLY_RS00740	COG1595	DNA-templated transcription, initiation
CELLY_RS00750	COG4206	TonB-dependent receptor
CELLY_RS00760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CELLY_RS00795	COG3279	Response regulator of the LytR AlgR family
CELLY_RS00805	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CELLY_RS00810	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CELLY_RS00840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELLY_RS00845	COG0259	pyridoxamine-phosphate oxidase activity
CELLY_RS00855	COG1234	tRNA 3'-trailer cleavage
CELLY_RS00865	COG0540	Belongs to the ATCase OTCase family
CELLY_RS00870	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CELLY_RS00875	COG0539	negative regulation of cytoplasmic translation
CELLY_RS00880	COG2823	Periplasmic or secreted lipoprotein
CELLY_RS00880	COG1652	LysM domain
CELLY_RS00885	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CELLY_RS00890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CELLY_RS00915	COG2270	Major facilitator Superfamily
CELLY_RS00930	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CELLY_RS00935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CELLY_RS00950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CELLY_RS00965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CELLY_RS00980	COG4974	Belongs to the 'phage' integrase family
CELLY_RS01005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CELLY_RS01010	COG2860	membrane
CELLY_RS01040	COG0714	Associated with various cellular activities
CELLY_RS01065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CELLY_RS01075	COG0482	sulfurtransferase activity
CELLY_RS01080	COG0706	membrane insertase activity
CELLY_RS01085	COG0504	CTP synthase activity
CELLY_RS01090	COG3530	Putative quorum-sensing-regulated virulence factor
CELLY_RS01110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CELLY_RS01110	COG0519	Catalyzes the synthesis of GMP from XMP
CELLY_RS01115	COG0076	glutamate decarboxylase activity
CELLY_RS01120	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CELLY_RS01130	COG1619	proteins homologs of microcin C7 resistance protein MccF
CELLY_RS01135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CELLY_RS01140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CELLY_RS01155	COG0116	Belongs to the methyltransferase superfamily
CELLY_RS01170	COG1272	protein, Hemolysin III
CELLY_RS01180	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CELLY_RS01185	COG1472	Belongs to the glycosyl hydrolase 3 family
CELLY_RS01190	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CELLY_RS01195	COG2814	Major facilitator Superfamily
CELLY_RS01200	COG0572	uridine kinase
CELLY_RS01210	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CELLY_RS01215	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CELLY_RS01215	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CELLY_RS01220	COG1192	Involved in chromosome partitioning
CELLY_RS01225	COG1475	DNA binding
CELLY_RS01235	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CELLY_RS01240	COG0681	Belongs to the peptidase S26 family
CELLY_RS01270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CELLY_RS01280	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CELLY_RS01290	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CELLY_RS01305	COG0105	UTP biosynthetic process
CELLY_RS01315	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CELLY_RS01325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CELLY_RS01330	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CELLY_RS01335	COG2195	Cleaves the N-terminal amino acid of tripeptides
CELLY_RS01345	COG1228	amidohydrolase
CELLY_RS01360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CELLY_RS01365	COG0501	Belongs to the peptidase M48B family
CELLY_RS01370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CELLY_RS01375	COG0735	belongs to the Fur family
CELLY_RS01380	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CELLY_RS01390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CELLY_RS01415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CELLY_RS01420	COG0702	epimerase
CELLY_RS01425	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CELLY_RS01430	COG2066	Belongs to the glutaminase family
CELLY_RS01440	COG2154	pterin-4-alpha-carbinolamine dehydratase
CELLY_RS01450	COG0708	Exodeoxyribonuclease III
CELLY_RS01465	COG4771	TonB-dependent receptor
CELLY_RS01470	COG0702	epimerase
CELLY_RS01485	COG2186	Transcriptional regulator
CELLY_RS01490	COG2271	Major facilitator Superfamily
CELLY_RS01530	COG1363	Peptidase, m42
CELLY_RS01535	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CELLY_RS01540	COG0124	histidyl-tRNA synthetase
CELLY_RS01555	COG0359	binds to the 23S rRNA
CELLY_RS01560	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CELLY_RS01565	COG0360	Binds together with S18 to 16S ribosomal RNA
CELLY_RS01570	COG3279	Response regulator of the LytR AlgR family
CELLY_RS01575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CELLY_RS01585	COG1295	ribonuclease BN
CELLY_RS01595	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CELLY_RS01610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CELLY_RS01615	COG2020	methyltransferase activity
CELLY_RS01620	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CELLY_RS01660	COG3264	Mechanosensitive ion channel
CELLY_RS01660	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CELLY_RS01665	COG1668	transmembrane transport
CELLY_RS01670	COG4152	abc transporter atp-binding protein
CELLY_RS01675	COG0484	heat shock protein binding
CELLY_RS01680	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CELLY_RS01695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CELLY_RS01715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CELLY_RS01720	COG0347	Belongs to the P(II) protein family
CELLY_RS01725	COG0004	ammonium transporteR
CELLY_RS01755	COG0668	transmembrane transport
CELLY_RS01760	COG1522	sequence-specific DNA binding
CELLY_RS01770	COG1703	isobutyryl-CoA mutase activity
CELLY_RS01770	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CELLY_RS01770	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CELLY_RS01775	COG0788	formyltetrahydrofolate deformylase activity
CELLY_RS01795	COG0024	Methionine aminopeptidase
CELLY_RS01835	COG1733	regulation of RNA biosynthetic process
CELLY_RS01855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CELLY_RS01900	COG1289	transmembrane transporter activity
CELLY_RS01910	COG0640	Transcriptional regulator
CELLY_RS01940	COG0284	orotidine-5'-phosphate decarboxylase activity
CELLY_RS01945	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CELLY_RS01965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CELLY_RS01990	COG0343	queuine tRNA-ribosyltransferase activity
CELLY_RS01995	COG3959	Transketolase, thiamine diphosphate binding domain
CELLY_RS02000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CELLY_RS02020	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CELLY_RS02025	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CELLY_RS02040	COG3250	beta-galactosidase activity
CELLY_RS02055	COG1063	alcohol dehydrogenase
CELLY_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
CELLY_RS02065	COG3119	arylsulfatase activity
CELLY_RS02065	COG3408	Glycogen debranching enzyme
CELLY_RS02070	COG1012	belongs to the aldehyde dehydrogenase family
CELLY_RS02075	COG4948	Mandelate Racemase Muconate Lactonizing
CELLY_RS02090	COG3254	rhamnose metabolic process
CELLY_RS02095	COG0738	Major facilitator superfamily
CELLY_RS02105	COG3618	amidohydrolase
CELLY_RS02110	COG0246	Mannitol dehydrogenase
CELLY_RS02115	COG2721	sulfolactate sulfo-lyase activity
CELLY_RS02120	COG1063	alcohol dehydrogenase
CELLY_RS02125	COG2205	protein histidine kinase activity
CELLY_RS02125	COG3292	Two component regulator propeller
CELLY_RS02125	COG0745	RESPONSE REGULATOR receiver
CELLY_RS02130	COG3119	arylsulfatase activity
CELLY_RS02135	COG3250	beta-galactosidase activity
CELLY_RS02140	COG3119	arylsulfatase activity
CELLY_RS02145	COG3119	arylsulfatase activity
CELLY_RS02150	COG3250	beta-galactosidase activity
CELLY_RS02160	COG3401	FG-GAP repeat protein
CELLY_RS02165	COG3119	arylsulfatase activity
CELLY_RS02170	COG3119	arylsulfatase activity
CELLY_RS02170	COG3408	Glycogen debranching enzyme
CELLY_RS02180	COG3119	arylsulfatase activity
CELLY_RS02180	COG3408	Glycogen debranching enzyme
CELLY_RS02190	COG3119	arylsulfatase activity
CELLY_RS02205	COG3119	arylsulfatase activity
CELLY_RS02235	COG3119	arylsulfatase activity
CELLY_RS02250	COG0702	epimerase
CELLY_RS02255	COG1629	transport
CELLY_RS02285	COG2207	Transcriptional regulator
CELLY_RS02285	COG1917	Cupin 2, conserved barrel domain protein
CELLY_RS02290	COG0673	inositol 2-dehydrogenase activity
CELLY_RS02300	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CELLY_RS02330	COG0415	Belongs to the DNA photolyase family
CELLY_RS02340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CELLY_RS02350	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CELLY_RS02355	COG0714	Associated with various cellular activities
CELLY_RS02390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CELLY_RS02395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELLY_RS02405	COG0154	amidase activity
CELLY_RS02410	COG0552	protein localization to endoplasmic reticulum
CELLY_RS02415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CELLY_RS02420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CELLY_RS02425	COG1058	Belongs to the CinA family
CELLY_RS02425	COG1546	Belongs to the CinA family
CELLY_RS02435	COG0179	Fumarylacetoacetate (FAA) hydrolase
CELLY_RS02450	COG0508	dehydrogenase complex catalyzes the overall conversion of
CELLY_RS02455	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CELLY_RS02470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CELLY_RS02490	COG1595	DNA-templated transcription, initiation
CELLY_RS02500	COG1595	DNA-templated transcription, initiation
CELLY_RS02510	COG2258	MOSC domain
CELLY_RS02540	COG1073	alpha beta
CELLY_RS02545	COG0561	phosphatase activity
CELLY_RS02565	COG1482	cell wall glycoprotein biosynthetic process
CELLY_RS02575	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CELLY_RS02600	COG2885	chlorophyll binding
CELLY_RS02615	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CELLY_RS02625	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CELLY_RS02630	COG0085	RNA polymerase activity
CELLY_RS02635	COG0222	ribosome binding
CELLY_RS02640	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CELLY_RS02645	COG0081	regulation of translation
CELLY_RS02650	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CELLY_RS02700	COG4974	Belongs to the 'phage' integrase family
CELLY_RS02705	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CELLY_RS02710	COG1960	acyl-CoA dehydrogenase activity
CELLY_RS02715	COG1555	photosystem II stabilization
CELLY_RS02715	COG1596	polysaccharide export
CELLY_RS02720	COG1115	amino acid carrier protein
CELLY_RS02740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CELLY_RS02750	COG2353	YceI-like domain
CELLY_RS02755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CELLY_RS02760	COG0512	Glutamine amidotransferase of anthranilate synthase
CELLY_RS02765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CELLY_RS02770	COG0134	indole-3-glycerol-phosphate synthase activity
CELLY_RS02775	COG0135	phosphoribosylanthranilate isomerase activity
CELLY_RS02780	COG0133	tryptophan synthase activity
CELLY_RS02785	COG0159	tryptophan synthase activity
CELLY_RS02790	COG0584	glycerophosphoryl diester phosphodiesterase
CELLY_RS02805	COG0488	(ABC) transporter
CELLY_RS02815	COG4773	Receptor
CELLY_RS02820	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CELLY_RS02835	COG3022	response to hydroperoxide
CELLY_RS02840	COG0564	pseudouridine synthase activity
CELLY_RS02845	COG2815	serine threonine protein kinase
CELLY_RS02845	COG0515	serine threonine protein kinase
CELLY_RS02850	COG1181	Belongs to the D-alanine--D-alanine ligase family
CELLY_RS02855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CELLY_RS02870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CELLY_RS02890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CELLY_RS02900	COG4589	Belongs to the CDS family
CELLY_RS02905	COG0688	phosphatidylethanolamine metabolic process
CELLY_RS02920	COG0525	valine-tRNA ligase activity
CELLY_RS02935	COG0436	Aminotransferase
CELLY_RS02940	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CELLY_RS02945	COG1595	DNA-templated transcription, initiation
CELLY_RS02965	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CELLY_RS02970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CELLY_RS02980	COG1663	tetraacyldisaccharide 4'-kinase activity
CELLY_RS02985	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CELLY_RS02995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CELLY_RS03000	COG0740	serine-type endopeptidase activity
CELLY_RS03010	COG3844	kynureninase activity
CELLY_RS03025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CELLY_RS03065	COG3340	Belongs to the peptidase S51 family
CELLY_RS03105	COG0501	Belongs to the peptidase M48B family
CELLY_RS03115	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CELLY_RS03130	COG2226	methyltransferase
CELLY_RS03135	COG1477	protein flavinylation
CELLY_RS03160	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CELLY_RS03165	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CELLY_RS03170	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CELLY_RS03175	COG1805	sodium ion transport
CELLY_RS03180	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CELLY_RS03190	COG2967	ApaG domain
CELLY_RS03195	COG1012	belongs to the aldehyde dehydrogenase family
CELLY_RS03200	COG0357	Ribosomal RNA small subunit methyltransferase G
CELLY_RS03205	COG3239	Fatty acid desaturase
CELLY_RS03215	COG0564	pseudouridine synthase activity
CELLY_RS03240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CELLY_RS03250	COG2226	methyltransferase
CELLY_RS03260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CELLY_RS03270	COG0191	fructose-bisphosphate aldolase activity
CELLY_RS03275	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CELLY_RS03280	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CELLY_RS03285	COG1185	polyribonucleotide nucleotidyltransferase activity
CELLY_RS03295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CELLY_RS03300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CELLY_RS03305	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CELLY_RS03310	COG1215	transferase activity, transferring glycosyl groups
CELLY_RS03315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CELLY_RS03370	COG4206	TonB-dependent receptor
CELLY_RS03370	COG1629	transport
CELLY_RS03375	COG0702	epimerase
CELLY_RS03380	COG1629	transport
CELLY_RS03400	COG1629	transport
CELLY_RS03400	COG4206	TonB-dependent receptor
CELLY_RS03405	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CELLY_RS03420	COG0321	lipoyl(octanoyl) transferase activity
CELLY_RS03425	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CELLY_RS03430	COG4682	membrane
CELLY_RS03440	COG0471	metal ion transport
CELLY_RS03460	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CELLY_RS03470	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CELLY_RS03500	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CELLY_RS03505	COG0739	heme binding
CELLY_RS03525	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CELLY_RS03545	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CELLY_RS03550	COG1629	transport
CELLY_RS03560	COG1160	GTP binding
CELLY_RS03580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CELLY_RS03585	COG1757	Na H antiporter
CELLY_RS03610	COG2814	Major facilitator Superfamily
CELLY_RS03620	COG0300	oxidoreductase activity
CELLY_RS03640	COG3279	Response regulator of the LytR AlgR family
CELLY_RS03660	COG3046	protein related to deoxyribodipyrimidine photolyase
CELLY_RS03670	COG0415	Belongs to the DNA photolyase family
CELLY_RS03680	COG1773	rubredoxin
CELLY_RS03685	COG0243	molybdopterin cofactor binding
CELLY_RS03700	COG1116	anion transmembrane transporter activity
CELLY_RS03705	COG1116	anion transmembrane transporter activity
CELLY_RS03710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CELLY_RS03715	COG1116	anion transmembrane transporter activity
CELLY_RS03715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CELLY_RS03730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CELLY_RS03735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CELLY_RS03735	COG2146	nitrite reductase [NAD(P)H] activity
CELLY_RS03745	COG4585	Histidine kinase
CELLY_RS03755	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CELLY_RS03760	COG1349	DNA-binding transcription factor activity
CELLY_RS03765	COG1629	transport
CELLY_RS03775	COG1649	PFAM Uncharacterised BCR, COG1649
CELLY_RS03780	COG4145	pantothenate transmembrane transporter activity
CELLY_RS03785	COG1472	Belongs to the glycosyl hydrolase 3 family
CELLY_RS03795	COG0488	(ABC) transporter
CELLY_RS03825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CELLY_RS03850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELLY_RS03875	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CELLY_RS03880	COG0459	protein refolding
CELLY_RS03905	COG0138	bifunctional purine biosynthesis protein purh
CELLY_RS03910	COG1077	Cell shape determining protein MreB Mrl
CELLY_RS03925	COG0768	penicillin binding
CELLY_RS03930	COG0772	Belongs to the SEDS family
CELLY_RS03945	COG0793	Belongs to the peptidase S41A family
CELLY_RS03950	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CELLY_RS03965	COG0791	NLP P60 protein
CELLY_RS03970	COG0658	competence protein
CELLY_RS03970	COG2333	competence protein COMEC
CELLY_RS03975	COG1349	DNA-binding transcription factor activity
CELLY_RS03985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CELLY_RS03990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CELLY_RS03995	COG3104	oligopeptide transport
CELLY_RS04040	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CELLY_RS04055	COG1054	Belongs to the UPF0176 family
CELLY_RS04065	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CELLY_RS04110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CELLY_RS04125	COG0463	Glycosyl transferase, family 2
CELLY_RS04130	COG1215	transferase activity, transferring glycosyl groups
CELLY_RS04145	COG0137	argininosuccinate synthase activity
CELLY_RS04150	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CELLY_RS04160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CELLY_RS04170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CELLY_RS04180	COG0165	Argininosuccinate lyase
CELLY_RS04185	COG1187	pseudouridine synthase activity
CELLY_RS04235	COG2081	HI0933 family
CELLY_RS04240	COG0584	glycerophosphoryl diester phosphodiesterase
CELLY_RS04245	COG1609	Transcriptional regulator
CELLY_RS04270	COG2839	Protein conserved in bacteria
CELLY_RS04275	COG2234	aminopeptidase activity
CELLY_RS04290	COG0583	DNA-binding transcription factor activity
CELLY_RS04295	COG2986	histidine ammonia-lyase
CELLY_RS04305	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CELLY_RS04310	COG3118	belongs to the thioredoxin family
CELLY_RS04315	COG0308	aminopeptidase N
CELLY_RS04330	COG2354	Protein conserved in bacteria
CELLY_RS04340	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CELLY_RS04345	COG4149	molybdate abc transporter
CELLY_RS04360	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CELLY_RS04405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CELLY_RS04410	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CELLY_RS04420	COG1132	(ABC) transporter
CELLY_RS04425	COG0633	Ferredoxin
CELLY_RS04430	COG0492	ferredoxin-NADP+ reductase activity
CELLY_RS04440	COG0489	protein tyrosine kinase activity
CELLY_RS04455	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CELLY_RS04465	COG5002	protein histidine kinase activity
CELLY_RS04470	COG0745	RESPONSE REGULATOR receiver
CELLY_RS04475	COG4771	TonB-dependent receptor
CELLY_RS04505	COG0519	Catalyzes the synthesis of GMP from XMP
CELLY_RS04535	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CELLY_RS04540	COG1968	undecaprenyl-diphosphatase activity
CELLY_RS04550	COG2177	Part of the ABC transporter FtsEX involved in
CELLY_RS04560	COG0495	leucyl-tRNA aminoacylation
CELLY_RS04565	COG0686	Belongs to the AlaDH PNT family
CELLY_RS04580	COG1858	cytochrome C peroxidase
CELLY_RS04595	COG1522	sequence-specific DNA binding
CELLY_RS04605	COG2363	Small membrane protein
CELLY_RS04610	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CELLY_RS04640	COG2814	Major facilitator Superfamily
CELLY_RS04850	COG1408	metallophosphoesterase
CELLY_RS04945	COG1309	transcriptional regulator
CELLY_RS04955	COG0596	Alpha beta hydrolase
CELLY_RS04970	COG0463	Glycosyl transferase, family 2
CELLY_RS04975	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CELLY_RS04990	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CELLY_RS05015	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CELLY_RS05025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CELLY_RS05030	COG5000	phosphorelay sensor kinase activity
CELLY_RS05045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CELLY_RS05090	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CELLY_RS05115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CELLY_RS05120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CELLY_RS05130	COG0612	Peptidase, M16
CELLY_RS05150	COG0629	single-stranded DNA binding
CELLY_RS05160	COG0776	regulation of translation
CELLY_RS05165	COG1530	ribonuclease E activity
CELLY_RS05170	COG2137	regulation of response to DNA damage stimulus
CELLY_RS05180	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CELLY_RS05185	COG2268	Band 7 protein
CELLY_RS05195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CELLY_RS05200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CELLY_RS05205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CELLY_RS05215	COG0156	8-amino-7-oxononanoate synthase activity
CELLY_RS05230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CELLY_RS05285	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CELLY_RS05295	COG0297	glycogen (starch) synthase activity
CELLY_RS05300	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CELLY_RS05305	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CELLY_RS05320	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CELLY_RS05325	COG0667	Aldo Keto reductase
CELLY_RS05335	COG0429	hydrolase of the alpha beta-hydrolase fold
CELLY_RS05370	COG0626	cystathionine gamma-synthase activity
CELLY_RS05375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CELLY_RS05380	COG1381	Involved in DNA repair and RecF pathway recombination
CELLY_RS05385	COG4206	TonB-dependent receptor
CELLY_RS05395	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CELLY_RS05410	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CELLY_RS05415	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CELLY_RS05420	COG0322	excinuclease ABC activity
CELLY_RS05430	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CELLY_RS05440	COG3483	tryptophan 2,3-dioxygenase activity
CELLY_RS05450	COG0166	Belongs to the GPI family
CELLY_RS05455	COG1629	transport
CELLY_RS05465	COG2356	endonuclease I
CELLY_RS05525	COG0423	glycine-tRNA ligase activity
CELLY_RS05535	COG0708	Exodeoxyribonuclease III
CELLY_RS05545	COG0659	secondary active sulfate transmembrane transporter activity
CELLY_RS05550	COG0579	oxidoreductase
CELLY_RS05560	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CELLY_RS05645	COG4953	penicillin-binding protein 1C
CELLY_RS05680	COG0662	Cupin 2, conserved barrel domain protein
CELLY_RS05685	COG1012	belongs to the aldehyde dehydrogenase family
CELLY_RS05690	COG2885	chlorophyll binding
CELLY_RS05715	COG4260	virion core protein, lumpy skin disease virus
CELLY_RS05725	COG4221	oxidoreductase activity
CELLY_RS05730	COG4989	oxidoreductase activity
CELLY_RS05740	COG0714	Associated with various cellular activities
CELLY_RS05755	COG2304	oxidoreductase activity
CELLY_RS05790	COG0659	secondary active sulfate transmembrane transporter activity
CELLY_RS05795	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CELLY_RS05805	COG0189	ligase activity
CELLY_RS05805	COG4067	protein conserved in archaea
CELLY_RS05810	COG2954	triphosphatase activity
CELLY_RS05815	COG0702	epimerase
CELLY_RS05820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CELLY_RS05825	COG0450	alkyl hydroperoxide reductase
CELLY_RS05840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CELLY_RS05845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CELLY_RS05855	COG1136	(ABC) transporter
CELLY_RS05860	COG0577	efflux transmembrane transporter activity
CELLY_RS05870	COG0577	efflux transmembrane transporter activity
CELLY_RS05890	COG0577	efflux transmembrane transporter activity
CELLY_RS05895	COG1136	(ABC) transporter
CELLY_RS05915	COG3852	Histidine kinase
CELLY_RS05920	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CELLY_RS05925	COG3842	ATPase activity
CELLY_RS05930	COG1505	serine-type exopeptidase activity
CELLY_RS05935	COG1280	lysine exporter protein (LysE YggA)
CELLY_RS05940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CELLY_RS05945	COG1970	mechanosensitive ion channel activity
CELLY_RS05950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CELLY_RS05955	COG1435	thymidine kinase activity
CELLY_RS05970	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CELLY_RS06005	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CELLY_RS06005	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CELLY_RS06015	COG4206	TonB-dependent receptor
CELLY_RS06045	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CELLY_RS06050	COG0720	synthase
CELLY_RS06065	COG0659	secondary active sulfate transmembrane transporter activity
CELLY_RS06085	COG0534	Mate efflux family protein
CELLY_RS06105	COG0612	Peptidase, M16
CELLY_RS06115	COG4771	TonB-dependent receptor
CELLY_RS06130	COG0662	Cupin 2, conserved barrel domain protein
CELLY_RS06130	COG2207	Transcriptional regulator
CELLY_RS06135	COG1629	transport
CELLY_RS06140	COG0702	epimerase
CELLY_RS06155	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CELLY_RS06210	COG3279	Response regulator of the LytR AlgR family
CELLY_RS06220	COG5002	protein histidine kinase activity
CELLY_RS06230	COG4251	negative regulation of phosphorylation
CELLY_RS06250	COG2885	chlorophyll binding
CELLY_RS06250	COG3047	cAMP biosynthetic process
CELLY_RS06255	COG0156	8-amino-7-oxononanoate synthase activity
CELLY_RS06260	COG1074	ATP-dependent DNA helicase activity
CELLY_RS06265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CELLY_RS06285	COG3341	Caulimovirus viroplasmin
CELLY_RS06285	COG0328	RNA-DNA hybrid ribonuclease activity
CELLY_RS06290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CELLY_RS06295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CELLY_RS06300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CELLY_RS06305	COG0571	ribonuclease III activity
CELLY_RS06315	COG0469	pyruvate kinase activity
CELLY_RS06365	COG0439	Biotin carboxylase
CELLY_RS06370	COG0511	ligase activity, forming carbon-carbon bonds
CELLY_RS06375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CELLY_RS06380	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CELLY_RS06390	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CELLY_RS06420	COG1629	transport
CELLY_RS06425	COG0702	epimerase
CELLY_RS06445	COG1472	Belongs to the glycosyl hydrolase 3 family
CELLY_RS06455	COG3119	arylsulfatase activity
CELLY_RS06465	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CELLY_RS06470	COG3422	double-strand break repair
CELLY_RS06495	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CELLY_RS06510	COG1360	Flagellar Motor Protein
CELLY_RS06515	COG0481	GTPase activity
CELLY_RS06525	COG3275	phosphorelay sensor kinase activity
CELLY_RS06550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CELLY_RS06565	COG0594	ribonuclease P activity
CELLY_RS06570	COG0793	Belongs to the peptidase S41A family
CELLY_RS06585	COG0791	NLP P60 protein
CELLY_RS06595	COG2153	protein acetylation
CELLY_RS06600	COG0698	ribose 5-phosphate isomerase
CELLY_RS06605	COG0557	exoribonuclease II activity
CELLY_RS06660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CELLY_RS06670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CELLY_RS06680	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CELLY_RS06685	COG0445	tRNA wobble uridine modification
CELLY_RS06725	COG4941	Belongs to the sigma-70 factor family
CELLY_RS06730	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CELLY_RS06740	COG0470	DNA polymerase III
CELLY_RS06745	COG0126	phosphoglycerate kinase activity
CELLY_RS06750	COG0791	NLP P60 protein
CELLY_RS06750	COG1388	LysM domain
CELLY_RS06765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CELLY_RS06770	COG4942	peptidase
CELLY_RS06810	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CELLY_RS06820	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CELLY_RS06845	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CELLY_RS06855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CELLY_RS06860	COG0151	Belongs to the GarS family
CELLY_RS06885	COG1309	transcriptional regulator
CELLY_RS06895	COG4771	TonB-dependent receptor
CELLY_RS06920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CELLY_RS06980	COG0356	it plays a direct role in the translocation of protons across the membrane
CELLY_RS06985	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CELLY_RS06990	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CELLY_RS06995	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CELLY_RS07000	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CELLY_RS07005	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CELLY_RS07020	COG0756	dUTP diphosphatase activity
CELLY_RS07025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CELLY_RS07035	COG0006	proline dipeptidase activity
CELLY_RS07050	COG1858	cytochrome C peroxidase
CELLY_RS07065	COG0189	ligase activity
CELLY_RS07075	COG1053	succinate dehydrogenase
CELLY_RS07080	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CELLY_RS07100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CELLY_RS07105	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CELLY_RS07115	COG1774	PSP1 C-terminal conserved region
CELLY_RS07125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CELLY_RS07145	COG0204	Acyl-transferase
CELLY_RS07150	COG0180	Tryptophanyl-tRNA synthetase
CELLY_RS07155	COG0545	Peptidyl-prolyl cis-trans isomerase
CELLY_RS07160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CELLY_RS07160	COG0758	DNA mediated transformation
CELLY_RS07170	COG1607	acyl-coa hydrolase
CELLY_RS07180	COG1309	transcriptional regulator
CELLY_RS07185	COG4221	oxidoreductase activity
CELLY_RS07195	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CELLY_RS07200	COG2855	membrane
CELLY_RS07205	COG0583	DNA-binding transcription factor activity
CELLY_RS07210	COG2169	Transcriptional regulator
CELLY_RS07210	COG1917	Cupin 2, conserved barrel domain protein
CELLY_RS07220	COG0346	lactoylglutathione lyase activity
CELLY_RS07230	COG0300	oxidoreductase activity
CELLY_RS07235	COG3275	phosphorelay sensor kinase activity
CELLY_RS07245	COG4771	TonB-dependent receptor
CELLY_RS07285	COG1012	belongs to the aldehyde dehydrogenase family
CELLY_RS07350	COG0584	glycerophosphoryl diester phosphodiesterase
CELLY_RS07360	COG2207	Transcriptional regulator
CELLY_RS07360	COG1917	Cupin 2, conserved barrel domain protein
CELLY_RS07560	COG4974	Belongs to the 'phage' integrase family
CELLY_RS07595	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CELLY_RS07605	COG0719	Fe-S assembly protein
CELLY_RS07610	COG0396	ATPase activity
CELLY_RS07615	COG0719	Fe-S assembly protein
CELLY_RS07625	COG2166	iron-sulfur cluster assembly
CELLY_RS07630	COG2151	metal-sulfur cluster biosynthetic enzyme
CELLY_RS07650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CELLY_RS07745	COG1981	membrane
CELLY_RS07750	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CELLY_RS07770	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CELLY_RS07780	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CELLY_RS07805	COG0408	coproporphyrinogen oxidase activity
CELLY_RS07810	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CELLY_RS07825	COG1131	(ABC) transporter
CELLY_RS07835	COG0113	porphobilinogen synthase activity
CELLY_RS07850	COG2382	esterase
CELLY_RS07855	COG1917	Cupin 2, conserved barrel domain protein
CELLY_RS07855	COG2169	Transcriptional regulator
CELLY_RS07865	COG1253	flavin adenine dinucleotide binding
CELLY_RS07890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CELLY_RS07910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CELLY_RS07920	COG0315	cyclic pyranopterin monophosphate synthase activity
CELLY_RS07930	COG3590	peptidase
CELLY_RS07945	COG1629	transport
CELLY_RS07950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CELLY_RS07955	COG1012	belongs to the aldehyde dehydrogenase family
CELLY_RS07985	COG1136	(ABC) transporter
CELLY_RS07990	COG0668	transmembrane transport
CELLY_RS07995	COG0783	Belongs to the Dps family
CELLY_RS08015	COG1012	belongs to the aldehyde dehydrogenase family
CELLY_RS08020	COG0793	Belongs to the peptidase S41A family
CELLY_RS08050	COG1418	mRNA catabolic process
CELLY_RS08055	COG0673	inositol 2-dehydrogenase activity
CELLY_RS08080	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CELLY_RS08130	COG1538	Outer membrane efflux protein
CELLY_RS08135	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CELLY_RS08135	COG1519	Transferase
CELLY_RS08145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CELLY_RS08155	COG5000	phosphorelay sensor kinase activity
CELLY_RS08160	COG1024	Enoyl-CoA hydratase
CELLY_RS08215	COG1999	signal sequence binding
CELLY_RS08220	COG0750	zinc metalloprotease
CELLY_RS08245	COG4771	TonB-dependent receptor
CELLY_RS08265	COG4771	TonB-dependent receptor
CELLY_RS08270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CELLY_RS08290	COG0590	tRNA wobble adenosine to inosine editing
CELLY_RS08295	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CELLY_RS08305	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CELLY_RS08340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CELLY_RS08345	COG0194	GDP metabolic process
CELLY_RS08350	COG1561	YicC-like family, N-terminal region
CELLY_RS08375	COG0673	inositol 2-dehydrogenase activity
CELLY_RS08400	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CELLY_RS08400	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CELLY_RS08410	COG3279	Response regulator of the LytR AlgR family
CELLY_RS08415	COG3275	phosphorelay sensor kinase activity
CELLY_RS08425	COG2095	MarC family integral membrane protein
CELLY_RS08470	COG4771	TonB-dependent receptor
CELLY_RS08475	COG1321	iron dependent repressor
CELLY_RS08480	COG0803	Belongs to the bacterial solute-binding protein 9 family
CELLY_RS08485	COG1121	(ABC) transporter
CELLY_RS08490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CELLY_RS08495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CELLY_RS08515	COG1960	acyl-CoA dehydrogenase activity
CELLY_RS08520	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CELLY_RS08525	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CELLY_RS08530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CELLY_RS08535	COG1051	belongs to the nudix hydrolase family
CELLY_RS08540	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CELLY_RS08545	COG0228	four-way junction DNA binding
CELLY_RS08580	COG2207	Transcriptional regulator
CELLY_RS08580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CELLY_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
CELLY_RS08660	COG0629	single-stranded DNA binding
CELLY_RS08670	COG2885	chlorophyll binding
CELLY_RS08680	COG1528	Iron-storage protein
CELLY_RS08685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CELLY_RS08685	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CELLY_RS08705	COG0792	nuclease activity
CELLY_RS08720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CELLY_RS08770	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CELLY_RS08780	COG0527	aspartate kinase activity
CELLY_RS08800	COG0346	lactoylglutathione lyase activity
CELLY_RS08810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CELLY_RS08820	COG0405	Gamma-glutamyltransferase
CELLY_RS08830	COG0076	glutamate decarboxylase activity
CELLY_RS08840	COG2239	Acts as a magnesium transporter
CELLY_RS08845	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CELLY_RS08860	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CELLY_RS08870	COG0196	riboflavin kinase activity
CELLY_RS08885	COG0193	aminoacyl-tRNA hydrolase activity
CELLY_RS08890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CELLY_RS08895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CELLY_RS08935	COG2720	vancomycin resistance protein
CELLY_RS08950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CELLY_RS08965	COG2205	protein histidine kinase activity
CELLY_RS08985	COG3119	arylsulfatase activity
CELLY_RS09000	COG4771	TonB-dependent receptor
CELLY_RS09005	COG3119	arylsulfatase activity
CELLY_RS09010	COG3119	arylsulfatase activity
CELLY_RS09030	COG3119	arylsulfatase activity
CELLY_RS09030	COG3408	Glycogen debranching enzyme
CELLY_RS09050	COG0800	Aldolase
CELLY_RS09060	COG1012	belongs to the aldehyde dehydrogenase family
CELLY_RS09065	COG4948	Mandelate Racemase Muconate Lactonizing
CELLY_RS09080	COG2207	Transcriptional regulator
CELLY_RS09090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CELLY_RS09095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CELLY_RS09115	COG2315	Protein conserved in bacteria
CELLY_RS09120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CELLY_RS09135	COG0508	dehydrogenase complex catalyzes the overall conversion of
CELLY_RS09140	COG1858	cytochrome C peroxidase
CELLY_RS09150	COG0084	hydrolase, TatD family'
CELLY_RS09155	COG0252	asparaginase activity
CELLY_RS09165	COG0811	peptide transport
CELLY_RS09195	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CELLY_RS09200	COG0017	Asparaginyl-tRNA synthetase
CELLY_RS09215	COG0233	cytoplasmic translational termination
CELLY_RS09220	COG0528	UMP kinase activity
CELLY_RS09225	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CELLY_RS09230	COG0052	Belongs to the universal ribosomal protein uS2 family
CELLY_RS09235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CELLY_RS09240	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CELLY_RS09255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CELLY_RS09255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CELLY_RS09260	COG1446	asparaginase
CELLY_RS09265	COG3142	Participates in the control of copper homeostasis
CELLY_RS09270	COG1408	metallophosphoesterase
CELLY_RS09295	COG0779	Required for maturation of 30S ribosomal subunits
CELLY_RS09300	COG2251	uridine kinase activity
CELLY_RS09300	COG0195	Participates in both transcription termination and antitermination
CELLY_RS09305	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CELLY_RS09325	COG0437	4 iron, 4 sulfur cluster binding
CELLY_RS09340	COG2010	Cytochrome c
CELLY_RS09355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CELLY_RS09365	COG2255	four-way junction helicase activity
CELLY_RS09375	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CELLY_RS09380	COG2022	thiamine diphosphate biosynthetic process
CELLY_RS09385	COG0352	thiamine-phosphate diphosphorylase activity
CELLY_RS09405	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CELLY_RS09410	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CELLY_RS09415	COG0281	malic enzyme
CELLY_RS09415	COG0280	phosphate acetyltransferase
CELLY_RS09420	COG0632	four-way junction helicase activity
CELLY_RS09430	COG0509	glycine decarboxylation via glycine cleavage system
CELLY_RS09450	COG0109	protoheme IX farnesyltransferase activity
CELLY_RS09455	COG1845	cytochrome c oxidase, subunit III
CELLY_RS09475	COG1999	signal sequence binding
CELLY_RS09480	COG2322	membrane
CELLY_RS09490	COG1136	(ABC) transporter
CELLY_RS09495	COG0577	efflux transmembrane transporter activity
CELLY_RS09495	COG1136	(ABC) transporter
CELLY_RS09500	COG0577	efflux transmembrane transporter activity
CELLY_RS09500	COG1136	(ABC) transporter
CELLY_RS09505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CELLY_RS09515	COG1214	PFAM Peptidase M22, glycoprotease
CELLY_RS09520	COG0668	transmembrane transport
CELLY_RS09530	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CELLY_RS09545	COG3275	phosphorelay sensor kinase activity
CELLY_RS09550	COG3279	Response regulator of the LytR AlgR family
CELLY_RS09555	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CELLY_RS09560	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CELLY_RS09580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CELLY_RS09590	COG2949	membrane
CELLY_RS09605	COG1522	sequence-specific DNA binding
CELLY_RS09610	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CELLY_RS09635	COG0662	Cupin 2, conserved barrel domain protein
CELLY_RS09635	COG2207	Transcriptional regulator
CELLY_RS09690	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CELLY_RS09700	COG1428	Deoxynucleoside kinase
CELLY_RS09730	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CELLY_RS09745	COG1950	PFAM Membrane protein of
CELLY_RS09750	COG0596	Alpha beta hydrolase
CELLY_RS09755	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CELLY_RS09765	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CELLY_RS09775	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CELLY_RS09795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CELLY_RS09800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CELLY_RS09805	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CELLY_RS09810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CELLY_RS09820	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CELLY_RS09830	COG0022	dehydrogenase e1 component
CELLY_RS09830	COG0508	dehydrogenase complex catalyzes the overall conversion of
CELLY_RS09840	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CELLY_RS09845	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CELLY_RS09850	COG1428	Deoxynucleoside kinase
CELLY_RS09865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CELLY_RS09875	COG0527	aspartate kinase activity
CELLY_RS09875	COG0460	homoserine dehydrogenase
CELLY_RS09885	COG1959	2 iron, 2 sulfur cluster binding
CELLY_RS09895	COG0175	sulfate reduction
CELLY_RS09900	COG0175	sulfate reduction
CELLY_RS09910	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CELLY_RS09915	COG1648	precorrin-2 dehydrogenase activity
CELLY_RS09915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CELLY_RS09920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CELLY_RS09920	COG1648	precorrin-2 dehydrogenase activity
CELLY_RS09925	COG0492	ferredoxin-NADP+ reductase activity
CELLY_RS09930	COG0646	methionine synthase
CELLY_RS09930	COG1410	methionine synthase
CELLY_RS09940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CELLY_RS09960	COG1131	(ABC) transporter
CELLY_RS09965	COG0077	Prephenate dehydratase
CELLY_RS09970	COG0436	Aminotransferase
CELLY_RS09975	COG0287	Prephenate dehydrogenase
CELLY_RS09980	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CELLY_RS09990	COG1162	GTPase activity
CELLY_RS09995	COG1490	D-aminoacyl-tRNA deacylase activity
CELLY_RS10020	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CELLY_RS10025	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CELLY_RS10040	COG1595	DNA-templated transcription, initiation
CELLY_RS10060	COG0358	DNA primase activity
CELLY_RS10075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CELLY_RS10110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CELLY_RS10120	COG2001	Belongs to the MraZ family
CELLY_RS10125	COG0275	rRNA processing
CELLY_RS10135	COG0768	penicillin binding
CELLY_RS10140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CELLY_RS10145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CELLY_RS10150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CELLY_RS10155	COG0772	Belongs to the SEDS family
CELLY_RS10160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CELLY_RS10165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CELLY_RS10180	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CELLY_RS10185	COG1610	YqeY-like protein
CELLY_RS10200	COG2197	response regulator
CELLY_RS10205	COG4585	Histidine kinase
CELLY_RS10210	COG0492	ferredoxin-NADP+ reductase activity
CELLY_RS10215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CELLY_RS10220	COG1278	Cold shock
CELLY_RS10230	COG0069	glutamate synthase activity
CELLY_RS10230	COG0070	glutamate synthase
CELLY_RS10230	COG0067	glutamate synthase
CELLY_RS10235	COG1960	acyl-CoA dehydrogenase activity
CELLY_RS10240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CELLY_RS10245	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CELLY_RS10250	COG0811	peptide transport
CELLY_RS10265	COG0285	dihydrofolate synthase activity
CELLY_RS10280	COG0363	glucosamine-6-phosphate deaminase activity
CELLY_RS10295	COG2217	Heavy metal translocating P-type atpase
CELLY_RS10310	COG3278	Belongs to the heme-copper respiratory oxidase family
CELLY_RS10325	COG0348	domain, Protein
CELLY_RS10340	COG0427	acetyl-CoA hydrolase
CELLY_RS10350	COG2217	Heavy metal translocating P-type atpase
CELLY_RS10370	COG1166	arginine decarboxylase activity
CELLY_RS10375	COG0010	Belongs to the arginase family
CELLY_RS10380	COG1899	peptidyl-lysine modification to peptidyl-hypusine
CELLY_RS10395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CELLY_RS10410	COG0295	cytidine deaminase activity
CELLY_RS10415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CELLY_RS10450	COG1127	ABC transporter
CELLY_RS10455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CELLY_RS10460	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
CELLY_RS10465	COG1215	transferase activity, transferring glycosyl groups
CELLY_RS10475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CELLY_RS10480	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CELLY_RS10480	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CELLY_RS10515	COG2226	methyltransferase
CELLY_RS10530	COG1510	regulation of RNA biosynthetic process
CELLY_RS10585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CELLY_RS10595	COG0339	signal peptide processing
CELLY_RS10615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CELLY_RS10620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CELLY_RS10625	COG0563	adenylate kinase activity
CELLY_RS10630	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CELLY_RS10645	COG3279	Response regulator of the LytR AlgR family
CELLY_RS10650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CELLY_RS10660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CELLY_RS10670	COG0443	Heat shock 70 kDa protein
CELLY_RS10680	COG2003	Belongs to the UPF0758 family
CELLY_RS10690	COG1011	Hydrolase
CELLY_RS10710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CELLY_RS10720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CELLY_RS10730	COG1629	transport
CELLY_RS10730	COG4206	TonB-dependent receptor
CELLY_RS10740	COG4771	TonB-dependent receptor
CELLY_RS10755	COG4771	TonB-dependent receptor
CELLY_RS10760	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CELLY_RS10765	COG0049	tRNA binding
CELLY_RS10770	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CELLY_RS10775	COG0051	transcription antitermination factor activity, RNA binding
CELLY_RS10780	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CELLY_RS10785	COG0088	Forms part of the polypeptide exit tunnel
CELLY_RS10790	COG0089	rRNA binding
CELLY_RS10795	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CELLY_RS10800	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CELLY_RS10805	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CELLY_RS10810	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CELLY_RS10815	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CELLY_RS10820	COG0255	Belongs to the universal ribosomal protein uL29 family
CELLY_RS10825	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CELLY_RS10830	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CELLY_RS10835	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CELLY_RS10840	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CELLY_RS10845	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CELLY_RS10850	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CELLY_RS10855	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CELLY_RS10865	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CELLY_RS10870	COG1841	ribosomal large subunit assembly
CELLY_RS10875	COG0200	Binds to the 23S rRNA
CELLY_RS10880	COG0201	protein transport
CELLY_RS10885	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CELLY_RS10890	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CELLY_RS10895	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CELLY_RS10900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CELLY_RS10905	COG0202	RNA polymerase activity
CELLY_RS10910	COG0203	ribosomal protein L17
CELLY_RS10915	COG0505	Belongs to the CarA family
CELLY_RS10920	COG0148	phosphopyruvate hydratase activity
CELLY_RS10940	COG0018	arginyl-trna synthetase
CELLY_RS10970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CELLY_RS10975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CELLY_RS10980	COG2897	thiosulfate sulfurtransferase activity
CELLY_RS10985	COG2378	regulation of single-species biofilm formation
CELLY_RS11000	COG0602	queuosine metabolic process
CELLY_RS11005	COG0433	COG0433 Predicted ATPase
CELLY_RS11015	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CELLY_RS11015	COG0662	Cupin 2, conserved barrel domain protein
CELLY_RS11055	COG3876	Protein conserved in bacteria
CELLY_RS11060	COG0577	efflux transmembrane transporter activity
CELLY_RS11070	COG0110	maltose O-acetyltransferase activity
CELLY_RS11085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CELLY_RS11085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CELLY_RS11090	COG0738	Major facilitator superfamily
CELLY_RS11095	COG2706	6-phosphogluconolactonase activity
CELLY_RS11100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CELLY_RS11105	COG0589	response to stress
CELLY_RS11170	COG2885	chlorophyll binding
CELLY_RS11180	COG0302	gtp cyclohydrolase
CELLY_RS11235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CELLY_RS11390	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CELLY_RS11395	COG1217	gtp-binding protein TYPA
CELLY_RS11425	COG3263	regulation of cellular component size
CELLY_RS11440	COG2076	Multidrug Resistance protein
CELLY_RS11445	COG1607	acyl-coa hydrolase
CELLY_RS11455	COG1047	Peptidyl-prolyl cis-trans
CELLY_RS11470	COG2884	Cell division ATP-binding protein ftsE
CELLY_RS11495	COG0367	asparagine synthase
CELLY_RS11500	COG0187	DNA topoisomerase II activity
CELLY_RS11520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CELLY_RS11525	COG1119	ATPase activity
CELLY_RS11540	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CELLY_RS11545	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CELLY_RS11550	COG0215	cysteine-tRNA ligase activity
CELLY_RS11555	COG0302	gtp cyclohydrolase
CELLY_RS11585	COG0442	prolyl-tRNA aminoacylation
CELLY_RS11600	COG0268	Binds directly to 16S ribosomal RNA
CELLY_RS11640	COG0101	tRNA pseudouridine synthase activity
CELLY_RS11645	COG1132	(ABC) transporter
CELLY_RS11655	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CELLY_RS11660	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CELLY_RS11685	COG0149	triose-phosphate isomerase activity
CELLY_RS11690	COG2264	protein methyltransferase activity
CELLY_RS11725	COG3279	Response regulator of the LytR AlgR family
CELLY_RS11745	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CELLY_RS11755	COG1629	transport
CELLY_RS11765	COG3537	Alpha-1,2-mannosidase
CELLY_RS11815	COG0702	epimerase
CELLY_RS11820	COG4771	TonB-dependent receptor
CELLY_RS11825	COG0745	RESPONSE REGULATOR receiver
CELLY_RS11825	COG3292	Two component regulator propeller
CELLY_RS11825	COG2205	protein histidine kinase activity
CELLY_RS11835	COG1028	Short-chain dehydrogenase reductase Sdr
CELLY_RS11855	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CELLY_RS11860	COG1085	galactose-1-phosphate uridylyltransferase
CELLY_RS11870	COG1609	Transcriptional regulator
CELLY_RS11880	COG0800	Aldolase
CELLY_RS11890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CELLY_RS11955	COG0210	DNA helicase
CELLY_RS11970	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CELLY_RS11985	COG1111	helicase
CELLY_RS11985	COG1205	dead DEAH box helicase
CELLY_RS11985	COG1111	helicase
CELLY_RS11985	COG1205	dead DEAH box helicase
CELLY_RS11990	COG1074	ATP-dependent DNA helicase activity
CELLY_RS12025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CELLY_RS12040	COG0174	glutamine synthetase
CELLY_RS12050	COG0825	malonyl-CoA metabolic process
CELLY_RS12055	COG0305	Participates in initiation and elongation during chromosome replication
CELLY_RS12065	COG0561	phosphatase activity
CELLY_RS12075	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CELLY_RS12080	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CELLY_RS12085	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CELLY_RS12090	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CELLY_RS12125	COG0083	homoserine kinase activity
CELLY_RS12130	COG0527	aspartate kinase activity
CELLY_RS12130	COG0460	homoserine dehydrogenase
CELLY_RS12135	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CELLY_RS12145	COG0542	response to heat
CELLY_RS12165	COG0183	Belongs to the thiolase family
CELLY_RS12175	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CELLY_RS12180	COG4770	biotin carboxylase activity
CELLY_RS12185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CELLY_RS12195	COG2819	hydrolase of the alpha beta superfamily
CELLY_RS12200	COG0366	Alpha amylase catalytic
CELLY_RS12205	COG1554	hydrolase, family 65, central catalytic
CELLY_RS12210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CELLY_RS12225	COG1629	transport
CELLY_RS12225	COG4206	TonB-dependent receptor
CELLY_RS12230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CELLY_RS12280	COG4771	TonB-dependent receptor
CELLY_RS12290	COG2207	Transcriptional regulator
CELLY_RS12295	COG4771	TonB-dependent receptor
CELLY_RS12300	COG0702	epimerase
CELLY_RS12305	COG1785	Belongs to the alkaline phosphatase family
CELLY_RS12320	COG1629	transport
CELLY_RS12320	COG4206	TonB-dependent receptor
CELLY_RS12330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CELLY_RS12335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CELLY_RS12340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CELLY_RS12380	COG4771	TonB-dependent receptor
CELLY_RS12405	COG3292	Two component regulator propeller
CELLY_RS12405	COG0745	RESPONSE REGULATOR receiver
CELLY_RS12405	COG2205	protein histidine kinase activity
CELLY_RS12435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CELLY_RS12440	COG0783	Belongs to the Dps family
CELLY_RS12445	COG4977	sequence-specific DNA binding
CELLY_RS12445	COG1917	Cupin 2, conserved barrel domain protein
CELLY_RS12450	COG0861	Integral membrane protein TerC family
CELLY_RS12455	COG4251	negative regulation of phosphorylation
CELLY_RS12460	COG2201	protein-glutamate methylesterase activity
CELLY_RS12475	COG1012	belongs to the aldehyde dehydrogenase family
CELLY_RS12510	COG2124	cytochrome p450
CELLY_RS12535	COG0561	phosphatase activity
CELLY_RS12540	COG1629	transport
CELLY_RS12565	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CELLY_RS12570	COG0492	ferredoxin-NADP+ reductase activity
CELLY_RS12575	COG1629	transport
CELLY_RS12575	COG4206	TonB-dependent receptor
CELLY_RS12590	COG4948	Mandelate Racemase Muconate Lactonizing
CELLY_RS12630	COG0583	DNA-binding transcription factor activity
CELLY_RS12635	COG0783	Belongs to the Dps family
CELLY_RS12650	COG2808	Putative FMN-binding domain
CELLY_RS12660	COG1187	pseudouridine synthase activity
CELLY_RS12665	COG3275	phosphorelay sensor kinase activity
CELLY_RS12685	COG3279	Response regulator of the LytR AlgR family
CELLY_RS12760	COG0612	Peptidase, M16
CELLY_RS12770	COG0545	Peptidyl-prolyl cis-trans isomerase
CELLY_RS12790	COG3387	PFAM Glycoside hydrolase 15-related
CELLY_RS12800	COG1960	acyl-CoA dehydrogenase activity
CELLY_RS12805	COG0183	Belongs to the thiolase family
CELLY_RS12810	COG1250	3-hydroxyacyl-CoA dehydrogenase
CELLY_RS12810	COG1024	Enoyl-CoA hydratase
CELLY_RS12820	COG1022	Amp-dependent synthetase and ligase
CELLY_RS12850	COG0047	phosphoribosylformylglycinamidine synthase activity
CELLY_RS12850	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CELLY_RS12860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CELLY_RS12860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CELLY_RS12880	COG1595	DNA-templated transcription, initiation
CELLY_RS12885	COG1132	(ABC) transporter
CELLY_RS12890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CELLY_RS12905	COG0254	rRNA binding
CELLY_RS12920	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CELLY_RS12945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CELLY_RS12965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CELLY_RS12975	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CELLY_RS12985	COG1454	alcohol dehydrogenase
CELLY_RS13000	COG0217	transcriptional regulatory protein
CELLY_RS13020	COG0612	Peptidase, M16
CELLY_RS13045	COG0628	permease
CELLY_RS13055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CELLY_RS13060	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CELLY_RS13070	COG0205	6-phosphofructokinase activity
CELLY_RS13085	COG0251	oxidation-reduction process
CELLY_RS13095	COG0860	N-Acetylmuramoyl-L-alanine amidase
CELLY_RS13105	COG2181	nitrate reductase activity
CELLY_RS13105	COG0247	lactate metabolic process
CELLY_RS13110	COG0247	lactate metabolic process
CELLY_RS13110	COG2181	nitrate reductase activity
CELLY_RS13125	COG0438	transferase activity, transferring glycosyl groups
CELLY_RS13130	COG2885	chlorophyll binding
CELLY_RS13155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CELLY_RS13165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CELLY_RS13185	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CELLY_RS13190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CELLY_RS13215	COG0367	asparagine synthase
CELLY_RS13235	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CELLY_RS13240	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CELLY_RS13255	COG1086	Polysaccharide biosynthesis protein
CELLY_RS13275	COG0297	glycogen (starch) synthase activity
CELLY_RS13280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CELLY_RS13285	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CELLY_RS13290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CELLY_RS13295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CELLY_RS13320	COG2824	Alkylphosphonate utilization operon protein PhnA
CELLY_RS13325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CELLY_RS13330	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CELLY_RS13350	COG0542	response to heat
CELLY_RS13370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CELLY_RS13385	COG4585	Histidine kinase
CELLY_RS13410	COG0300	oxidoreductase activity
CELLY_RS13415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CELLY_RS13425	COG0488	(ABC) transporter
CELLY_RS13445	COG0473	3-isopropylmalate dehydrogenase activity
CELLY_RS13450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CELLY_RS13460	COG0564	pseudouridine synthase activity
CELLY_RS13465	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CELLY_RS13480	COG2936	dipeptidyl-peptidase activity
CELLY_RS13485	COG1760	l-serine dehydratase
CELLY_RS13490	COG0443	Heat shock 70 kDa protein
CELLY_RS13500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CELLY_RS13520	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CELLY_RS13540	COG1575	Belongs to the MenA family. Type 1 subfamily
CELLY_RS13545	COG0784	Response regulator, receiver
CELLY_RS13555	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CELLY_RS13570	COG0318	PFAM AMP-dependent synthetase and ligase
CELLY_RS13575	COG4771	TonB-dependent receptor
CELLY_RS13580	COG2304	oxidoreductase activity
CELLY_RS13585	COG2271	Major facilitator Superfamily
CELLY_RS13590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CELLY_RS13600	COG0488	(ABC) transporter
CELLY_RS13605	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CELLY_RS13645	COG1393	Belongs to the ArsC family
CELLY_RS13650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CELLY_RS13665	COG3422	double-strand break repair
CELLY_RS13680	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CELLY_RS13685	COG1770	oligopeptidase
CELLY_RS13695	COG0156	8-amino-7-oxononanoate synthase activity
CELLY_RS13735	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CELLY_RS13740	COG1595	DNA-templated transcription, initiation
CELLY_RS13745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CELLY_RS13750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CELLY_RS13760	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CELLY_RS13760	COG0321	lipoyl(octanoyl) transferase activity
CELLY_RS13770	COG0400	carboxylic ester hydrolase activity
CELLY_RS13785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CELLY_RS13810	COG0129	dihydroxy-acid dehydratase activity
CELLY_RS13815	COG0028	Belongs to the TPP enzyme family
CELLY_RS13820	COG0440	acetolactate synthase activity
CELLY_RS13825	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CELLY_RS13830	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CELLY_RS13835	COG1012	belongs to the aldehyde dehydrogenase family
CELLY_RS13850	COG2814	Major facilitator Superfamily
CELLY_RS13870	COG0066	3-isopropylmalate dehydratase activity
CELLY_RS13875	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CELLY_RS13880	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CELLY_RS13885	COG0308	aminopeptidase N
CELLY_RS13915	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CELLY_RS13920	COG0069	glutamate synthase activity
CELLY_RS13925	COG1473	amidohydrolase
CELLY_RS13945	COG0009	L-threonylcarbamoyladenylate synthase
CELLY_RS13985	COG1611	Belongs to the LOG family
CELLY_RS13990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CELLY_RS14020	COG2217	Heavy metal translocating P-type atpase
CELLY_RS14035	COG1741	Belongs to the pirin family
CELLY_RS14045	COG0697	spore germination
CELLY_RS14050	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CELLY_RS14085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CELLY_RS14090	COG0746	molybdenum cofactor guanylyltransferase activity
CELLY_RS14090	COG0315	cyclic pyranopterin monophosphate synthase activity
CELLY_RS14100	COG0303	'Molybdopterin
CELLY_RS14105	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CELLY_RS14115	COG1595	DNA-templated transcription, initiation
CELLY_RS14130	COG1573	uracil-dna glycosylase
CELLY_RS14140	COG0513	Belongs to the DEAD box helicase family
CELLY_RS14155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CELLY_RS14170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CELLY_RS14180	COG0247	lactate metabolic process
CELLY_RS14180	COG0277	FAD linked oxidase domain protein
CELLY_RS14190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CELLY_RS14195	COG1301	dicarboxylic acid transport
CELLY_RS14205	COG1629	transport
CELLY_RS14205	COG4206	TonB-dependent receptor
CELLY_RS14210	COG0668	transmembrane transport
CELLY_RS14215	COG3011	Protein conserved in bacteria
CELLY_RS14235	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CELLY_RS14245	COG0513	Belongs to the DEAD box helicase family
CELLY_RS14250	COG1028	Short-chain dehydrogenase reductase Sdr
CELLY_RS14260	COG1278	Cold shock
CELLY_RS14280	COG1979	alcohol dehydrogenase
CELLY_RS14285	COG2130	NADP-dependent
CELLY_RS14295	COG1309	transcriptional regulator
CELLY_RS14300	COG1187	pseudouridine synthase activity
CELLY_RS14305	COG0339	signal peptide processing
CELLY_RS14320	COG3279	Response regulator of the LytR AlgR family
CELLY_RS14325	COG3275	phosphorelay sensor kinase activity
CELLY_RS14385	COG0071	Belongs to the small heat shock protein (HSP20) family
CELLY_RS14400	COG0778	Nitroreductase
CELLY_RS14405	COG0604	alcohol dehydrogenase
CELLY_RS14425	COG2207	Transcriptional regulator
CELLY_RS14430	COG1024	Enoyl-CoA hydratase
CELLY_RS14445	COG2249	NAD(P)H dehydrogenase (quinone) activity
CELLY_RS14465	COG1902	pentaerythritol trinitrate reductase activity
CELLY_RS14485	COG1879	ABC-type sugar transport system periplasmic component
CELLY_RS14495	COG1172	Belongs to the binding-protein-dependent transport system permease family
CELLY_RS14500	COG0246	Mannitol dehydrogenase
CELLY_RS14505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CELLY_RS14530	COG2274	protein secretion by the type I secretion system
CELLY_RS14560	COG1278	Cold shock
CELLY_RS14565	COG0590	tRNA wobble adenosine to inosine editing
CELLY_RS14600	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CELLY_RS14620	COG1715	Restriction endonuclease
CELLY_RS14635	COG0401	homolog of Blt101
CELLY_RS14645	COG3665	Urea carboxylase-associated protein
CELLY_RS14690	COG0022	dehydrogenase e1 component
CELLY_RS14710	COG0813	purine-nucleoside phosphorylase activity
CELLY_RS14720	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CELLY_RS14725	COG1288	antiporter activity
CELLY_RS14730	COG0513	Belongs to the DEAD box helicase family
CELLY_RS14765	COG5002	protein histidine kinase activity
CELLY_RS14770	COG1607	acyl-coa hydrolase
CELLY_RS14790	COG1045	serine acetyltransferase
CELLY_RS14820	COG0745	RESPONSE REGULATOR receiver
CELLY_RS14825	COG5002	protein histidine kinase activity
CELLY_RS14830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CELLY_RS14830	COG0140	phosphoribosyl-ATP diphosphatase activity
CELLY_RS14835	COG0107	imidazoleglycerol-phosphate synthase activity
CELLY_RS14840	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CELLY_RS14850	COG0131	Imidazoleglycerol-phosphate dehydratase
CELLY_RS14855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CELLY_RS14860	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CELLY_RS14865	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CELLY_RS14880	COG1028	Short-chain dehydrogenase reductase Sdr
CELLY_RS14890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CELLY_RS14895	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CELLY_RS14900	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CELLY_RS14905	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CELLY_RS14910	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CELLY_RS14910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CELLY_RS14915	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CELLY_RS14920	COG1078	dGTPase activity
CELLY_RS14925	COG2204	response regulator
CELLY_RS14950	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CELLY_RS14965	COG1522	sequence-specific DNA binding
CELLY_RS15000	COG0012	GTP binding
CELLY_RS15005	COG1629	transport
CELLY_RS15010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CELLY_RS15020	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CELLY_RS15025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CELLY_RS15055	COG4771	TonB-dependent receptor
CELLY_RS15095	COG0302	gtp cyclohydrolase
CELLY_RS15100	COG1136	(ABC) transporter
CELLY_RS15115	COG1984	allophanate hydrolase subunit 2
CELLY_RS15120	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CELLY_RS15145	COG0606	chelatase, subunit chli
CELLY_RS15155	COG0037	tRNA processing
CELLY_RS15160	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CELLY_RS15180	COG0351	phosphomethylpyrimidine kinase
CELLY_RS15180	COG0352	thiamine-phosphate diphosphorylase activity
CELLY_RS15185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CELLY_RS15190	COG1522	sequence-specific DNA binding
CELLY_RS15195	COG0626	cystathionine gamma-synthase activity
CELLY_RS15200	COG1757	Na H antiporter
CELLY_RS15205	COG0450	alkyl hydroperoxide reductase
CELLY_RS15225	COG0753	catalase activity
CELLY_RS15235	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CELLY_RS15240	COG1674	ftsk spoiiie
CELLY_RS15255	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CELLY_RS15255	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CELLY_RS15260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CELLY_RS15355	COG0589	response to stress
CELLY_RS15400	COG2072	flavoprotein involved in K transport
CELLY_RS15420	COG3738	Protein conserved in bacteria
CELLY_RS15455	COG3279	Response regulator of the LytR AlgR family
CELLY_RS15460	COG0745	RESPONSE REGULATOR receiver
CELLY_RS15460	COG2972	Histidine kinase
CELLY_RS15525	COG2814	Major facilitator Superfamily
CELLY_RS15525	COG0477	Major facilitator Superfamily
CELLY_RS15530	COG2115	Belongs to the xylose isomerase family
CELLY_RS15535	COG1070	Carbohydrate kinase
CELLY_RS15635	COG3279	Response regulator of the LytR AlgR family
CELLY_RS15650	COG2909	trisaccharide binding
CELLY_RS15670	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CELLY_RS15680	COG4206	TonB-dependent receptor
CELLY_RS15690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CELLY_RS15695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CELLY_RS15705	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CELLY_RS15755	COG2234	aminopeptidase activity
CELLY_RS15775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CELLY_RS15780	COG0626	cystathionine gamma-synthase activity
CELLY_RS15790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CELLY_RS15790	COG1333	cytochrome c biogenesis protein
CELLY_RS15815	COG0424	maF-like protein
CELLY_RS15830	COG0598	Magnesium transport protein CorA
CELLY_RS15870	COG0702	epimerase
CELLY_RS15880	COG0302	gtp cyclohydrolase
CELLY_RS15890	COG1028	Short-chain dehydrogenase reductase Sdr
CELLY_RS15895	COG0386	Belongs to the glutathione peroxidase family
CELLY_RS15920	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CELLY_RS15940	COG0514	ATP-dependent DNA helicase (RecQ)
CELLY_RS15945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CELLY_RS15955	COG1678	Uncharacterized ACR, COG1678
CELLY_RS16000	COG1271	oxidase subunit
CELLY_RS16005	COG1294	oxidase, subunit
CELLY_RS16010	COG1396	sequence-specific DNA binding
CELLY_RS16020	COG3012	SEC-C Motif Domain Protein
CELLY_RS16035	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CELLY_RS16040	COG1702	phosphate starvation-inducible protein PhoH
CELLY_RS16065	COG0592	DNA-directed DNA polymerase activity
CELLY_RS16085	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CELLY_RS16165	COG2217	Heavy metal translocating P-type atpase
CELLY_RS16215	COG3938	Belongs to the proline racemase family
CELLY_RS16220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CELLY_RS16225	COG3279	Response regulator of the LytR AlgR family
CELLY_RS16230	COG3275	phosphorelay sensor kinase activity
CELLY_RS16290	COG1472	Belongs to the glycosyl hydrolase 3 family
CELLY_RS16310	COG0702	epimerase
CELLY_RS16315	COG4771	TonB-dependent receptor
CELLY_RS16320	COG2205	protein histidine kinase activity
CELLY_RS16320	COG3292	Two component regulator propeller
CELLY_RS16320	COG0745	RESPONSE REGULATOR receiver
CELLY_RS16395	COG1629	transport
CELLY_RS16395	COG4206	TonB-dependent receptor
CELLY_RS16405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CELLY_RS16405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CELLY_RS16425	COG0823	Involved in the tonB-independent uptake of proteins
CELLY_RS16425	COG1506	peptidase
CELLY_RS16430	COG0673	inositol 2-dehydrogenase activity
CELLY_RS16435	COG1250	3-hydroxyacyl-CoA dehydrogenase
CELLY_RS16445	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CELLY_RS16450	COG2176	DNA-directed DNA polymerase activity
CELLY_RS16455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CELLY_RS16460	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CELLY_RS16475	COG0237	dephospho-CoA kinase activity
CELLY_RS16485	COG0463	Glycosyl transferase, family 2
CELLY_RS16490	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CELLY_RS16495	COG0497	DNA recombination
CELLY_RS16520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CELLY_RS16530	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CELLY_RS16535	COG2890	protein-(glutamine-N5) methyltransferase activity
CELLY_RS16545	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CELLY_RS16545	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CELLY_RS16550	COG1011	Hydrolase
CELLY_RS16555	COG0697	spore germination
CELLY_RS16560	COG1739	Uncharacterized protein family UPF0029
CELLY_RS16585	COG0745	RESPONSE REGULATOR receiver
CELLY_RS16585	COG2972	Histidine kinase
CELLY_RS16590	COG4251	negative regulation of phosphorylation
CELLY_RS16630	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CELLY_RS16640	COG3290	protein histidine kinase activity
CELLY_RS16655	COG2205	protein histidine kinase activity
CELLY_RS16655	COG5002	protein histidine kinase activity
CELLY_RS16655	COG0784	Response regulator, receiver
CELLY_RS16660	COG3850	Histidine kinase
CELLY_RS16660	COG4999	Histidine kinase
CELLY_RS16660	COG3437	response regulator, receiver
CELLY_RS16660	COG2205	protein histidine kinase activity
CELLY_RS16740	COG2207	Transcriptional regulator
CELLY_RS16745	COG0457	Tetratricopeptide repeat
CELLY_RS16755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CELLY_RS16780	COG1401	restriction endodeoxyribonuclease activity
CELLY_RS16785	COG0732	type I restriction modification DNA specificity domain
CELLY_RS16800	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CELLY_RS16820	COG4191	Histidine kinase