locus-tag	class	description
HKK73_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HKK73_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HKK73_RS00015	ENOG4108J5G	6-phosphogluconate dehydrogenase
HKK73_RS00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HKK73_RS00025	ENOG4105K7N	UPF0232 protein
HKK73_RS00035	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HKK73_RS00040	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HKK73_RS00075	ENOG4105ZJT	Cell division protein CrgA
HKK73_RS00085	ENOG4108U4N	(sortase) family
HKK73_RS00100	ENOG4105D9P	serine threonine protein kinase
HKK73_RS00105	ENOG4107TPY	serine threonine protein kinase
HKK73_RS00110	ENOG4105CJN	penicillin-binding protein
HKK73_RS00125	ENOG4105HZM	Fha domain containing protein
HKK73_RS00165	ENOG4105E0A	ABC, transporter
HKK73_RS00170	ENOG4105TVJ	transport system, permease
HKK73_RS00175	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HKK73_RS00205	ENOG4105KJF	protein tyrosine phosphatase
HKK73_RS00235	ENOG4105CHM	Aminotransferase
HKK73_RS00250	ENOG4105EMY	transcriptional regulator
HKK73_RS00255	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HKK73_RS00260	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HKK73_RS00265	ENOG4105ES5	Histidine kinase
HKK73_RS00275	ENOG4105CND	Glycosyl transferase, family 2
HKK73_RS00285	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKK73_RS00290	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HKK73_RS00295	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HKK73_RS00310	ENOG4105BZU	Histidine kinase
HKK73_RS00335	ENOG4105M6F	mutator MutT protein
HKK73_RS00355	ENOG4105CH2	amidohydrolase
HKK73_RS00365	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HKK73_RS00370	ENOG4105D6Z	AFG1 family ATPase
HKK73_RS00395	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
HKK73_RS00415	ENOG4107RCI	amp-dependent synthetase and ligase
HKK73_RS00425	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HKK73_RS00440	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HKK73_RS00540	ENOG4105ETE	Transcriptional regulator (LacI family
HKK73_RS00550	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HKK73_RS00560	ENOG4107U9T	Pfam:Ribonuclease_BN
HKK73_RS00565	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HKK73_RS00610	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HKK73_RS00625	ENOG4107YCY	Transcriptional regulator
HKK73_RS00630	ENOG4105DEF	Extracellular solute-binding protein, family 5
HKK73_RS00635	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HKK73_RS00645	ENOG4108JQ7	(ABC) transporter
HKK73_RS00650	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HKK73_RS00660	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HKK73_RS00700	ENOG4105F9F	transposase
HKK73_RS00710	ENOG4108C33	Resolvase
HKK73_RS00745	ENOG4107SGM	protein serine threonine phosphatase
HKK73_RS00750	ENOG4107QZ7	Cellulose synthase catalytic subunit
HKK73_RS00755	ENOG4105WN5	stage II sporulation protein
HKK73_RS00825	ENOG4105KV4	Transcriptional regulator
HKK73_RS00830	ENOG4105KK4	UPF0060 membrane protein
HKK73_RS00845	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HKK73_RS00865	ENOG4105CSU	acyl-Coa dehydrogenase
HKK73_RS00890	ENOG4105HFS	5'-3' exonuclease
HKK73_RS00900	ENOG41085FC	arsR family transcriptional regulator
HKK73_RS00905	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HKK73_RS00910	ENOG4108UXE	Protein tyrosine phosphatase
HKK73_RS00915	ENOG4105HS2	Arsenate reductase
HKK73_RS00925	ENOG4105K5X	acetyltransferase
HKK73_RS00935	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS00990	ENOG4105K6V	RNA polymerase
HKK73_RS01000	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HKK73_RS01005	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS01030	ENOG4105CNT	hydrolase family 2
HKK73_RS01040	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HKK73_RS01070	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HKK73_RS01075	ENOG4105FQP	Beta-lactamase
HKK73_RS01080	ENOG4107T5V	SNARE associated Golgi
HKK73_RS01090	ENOG4105C87	Aminotransferase class I and II
HKK73_RS01130	ENOG4107R6U	sodium dicarboxylate symporter
HKK73_RS01140	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS01145	ENOG4105BZU	Histidine kinase
HKK73_RS01160	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HKK73_RS01180	ENOG4105CVK	Glutamate decarboxylase
HKK73_RS01185	ENOG4105E5D	amino acid
HKK73_RS01190	ENOG4105CRK	lysyL-tRNA synthetase
HKK73_RS01205	ENOG4105E5D	amino acid
HKK73_RS01210	ENOG4105CI2	imidazolone-5-propionate hydrolase
HKK73_RS01215	ENOG4105VEQ	Cold shock protein
HKK73_RS01250	ENOG4108PG2	copper resistance
HKK73_RS01270	ENOG4105KDC	50s ribosomal protein l28
HKK73_RS01275	ENOG4105W0E	50S ribosomal protein L33
HKK73_RS01280	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HKK73_RS01285	ENOG4105NRA	50s ribosomal protein l31 type b
HKK73_RS01300	ENOG4108426	dNA-binding protein
HKK73_RS01375	ENOG4105K64	Glycosyl transferase, family 2
HKK73_RS01390	ENOG4105CPP	Dehydrogenase, E1 component
HKK73_RS01395	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
HKK73_RS01400	ENOG4107QX3	carboxylase
HKK73_RS01410	ENOG4105C1G	acyl-Coa dehydrogenase
HKK73_RS01430	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HKK73_RS01435	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HKK73_RS01445	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HKK73_RS01465	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HKK73_RS01470	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HKK73_RS01505	ENOG4108M15	ABC transporter
HKK73_RS01525	ENOG4105VPX	protein, conserved in bacteria
HKK73_RS01550	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HKK73_RS01555	ENOG4105D52	delta-aminolevulinic acid dehydratase
HKK73_RS01565	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HKK73_RS01575	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HKK73_RS01580	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HKK73_RS01585	ENOG4105CWX	Alpha-1,2-mannosidase
HKK73_RS01590	ENOG4107R33	ppx gppa phosphatase
HKK73_RS01595	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HKK73_RS01600	ENOG4105DR5	peptidase
HKK73_RS01610	ENOG4105M6F	mutator MutT protein
HKK73_RS01615	ENOG4105F32	YngK protein
HKK73_RS01635	ENOG4107QTF	adenylosuccinate lyase
HKK73_RS01650	ENOG41082T9	Membrane
HKK73_RS01655	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HKK73_RS01685	ENOG4105CPP	Dehydrogenase, E1 component
HKK73_RS01690	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
HKK73_RS01705	ENOG4105DQQ	Major facilitator superfamily MFS_1
HKK73_RS01715	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
HKK73_RS01720	ENOG4107QZF	nitrite reductase NADPH large subunit
HKK73_RS01725	ENOG4107QZF	nitrite reductase NADPH large subunit
HKK73_RS01730	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HKK73_RS01755	ENOG4108Z4X	TRANSCRIPTIONal
HKK73_RS01795	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HKK73_RS01800	ENOG410905P	Pyridoxamine 5-phosphate
HKK73_RS01815	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HKK73_RS01845	ENOG4105EYF	MMPL domain protein
HKK73_RS01900	ENOG4105C5Y	PTS System
HKK73_RS01915	ENOG4105FDP	GntR family transcriptional regulator
HKK73_RS01925	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HKK73_RS01930	ENOG410849S	phosphocarrier protein (HPr)
HKK73_RS01935	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
HKK73_RS01950	ENOG4105E8G	Major facilitator Superfamily
HKK73_RS01965	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS01970	ENOG4105BZU	Histidine kinase
HKK73_RS01990	ENOG4105CUV	Homoserine Kinase
HKK73_RS01995	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HKK73_RS02000	ENOG4105C7K	acetolactate synthase
HKK73_RS02005	ENOG4108JU3	Alkyl hydroperoxide reductase
HKK73_RS02070	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HKK73_RS02075	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HKK73_RS02105	ENOG4107R8N	Glycosyl transferase, family 2
HKK73_RS02125	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HKK73_RS02130	ENOG4105EHG	Permease protein
HKK73_RS02165	ENOG4105EUB	pirin domain protein
HKK73_RS02210	ENOG4105CXK	mandelate racemase muconate lactonizing
HKK73_RS02215	ENOG4105DRR	Transcriptional regulator, GntR family
HKK73_RS02235	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HKK73_RS02255	ENOG4105ETE	Transcriptional regulator (LacI family
HKK73_RS02260	ENOG4105EPJ	extracellular solute-binding protein family 1
HKK73_RS02265	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
HKK73_RS02270	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
HKK73_RS02270	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
HKK73_RS02275	ENOG4107AQZ	Membrane
HKK73_RS02280	ENOG4108VC7	Protein of unknown function (DUF2587)
HKK73_RS02295	ENOG4105GWZ	Roadblock lc7 family protein
HKK73_RS02335	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HKK73_RS02345	ENOG4107XI7	Tetr family transcriptional regulator
HKK73_RS02350	ENOG4106HB6	Alpha beta hydrolase
HKK73_RS02390	ENOG4105E2R	ROK family
HKK73_RS02395	ENOG4105DFW	ABC transporter
HKK73_RS02400	ENOG4105C2J	ABC transporter
HKK73_RS02405	ENOG4108HWW	ABC transporter
HKK73_RS02410	ENOG41060NJ	transcriptional regulator
HKK73_RS02420	ENOG4107QKS	N-acylglucosamine 2-epimerase
HKK73_RS02440	ENOG4105DHP	deoxycytidine triphosphate deaminase
HKK73_RS02450	ENOG4105D65	subunit l
HKK73_RS02455	ENOG4105MKQ	Monovalent cation H antiporter subunit C
HKK73_RS02460	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HKK73_RS02475	ENOG4105KJM	monovalent cation h antiporter subunit g
HKK73_RS02485	ENOG4105K4I	Scp-like extracellular
HKK73_RS02495	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HKK73_RS02520	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HKK73_RS02530	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HKK73_RS02540	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS02545	ENOG4108ZGX	Histidine kinase
HKK73_RS02555	ENOG4105CJ1	ABC, transporter
HKK73_RS02595	ENOG4108MRH	transcriptional regulatory protein
HKK73_RS02600	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HKK73_RS02620	ENOG4105SHT	UspA domain-containing protein
HKK73_RS02625	ENOG4105EMU	Dehydrogenase
HKK73_RS02630	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HKK73_RS02680	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HKK73_RS02685	ENOG4105C12	Phosphoribosylglycinamide synthetase
HKK73_RS02690	ENOG4106T9R	serine protease
HKK73_RS02700	ENOG4105C8V	SAICAR synthetase
HKK73_RS02720	ENOG410839H	phosphoribosylformylglycinamidine synthase
HKK73_RS02725	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HKK73_RS02740	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HKK73_RS02770	ENOG4105DEN	Luciferase family
HKK73_RS02780	ENOG4107QKA	exodeoxyribonuclease V beta
HKK73_RS02790	ENOG4105DXX	methyltransferase
HKK73_RS02805	ENOG4105MGE	Rhodanese domain protein
HKK73_RS02810	ENOG4105C9B	Cysteine desulfurase
HKK73_RS02835	ENOG4105CHR	reductase
HKK73_RS02840	ENOG4105CHU	acetyl-coa acetyltransferase
HKK73_RS02865	ENOG4105C85	amino acid
HKK73_RS02870	ENOG4108594	Permease of the drug metabolite transporter
HKK73_RS02875	ENOG4106NZI	LysR family Transcriptional regulator
HKK73_RS02895	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
HKK73_RS02905	ENOG4105EYF	MMPL domain protein
HKK73_RS02935	ENOG4105E5Q	amino acid AbC transporter
HKK73_RS02940	ENOG4105CDA	abc transporter atp-binding protein
HKK73_RS02945	ENOG4105EAB	amino acid AbC transporter
HKK73_RS02955	ENOG4108DBC	nitroreductase
HKK73_RS02960	ENOG4105DEN	Luciferase family
HKK73_RS02970	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HKK73_RS02975	ENOG4105FBW	Monooxygenase
HKK73_RS02985	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HKK73_RS02995	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HKK73_RS03010	ENOG4105CPC	Aldo Keto reductase
HKK73_RS03025	ENOG4108UZX	fmn reductase
HKK73_RS03030	ENOG4105D82	Glutamate dehydrogenase
HKK73_RS03045	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HKK73_RS03055	ENOG4106N3A	copper homeostasis protein cutc
HKK73_RS03070	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HKK73_RS03075	ENOG4105C3U	ABC transporter
HKK73_RS03080	ENOG4108JQ7	(ABC) transporter
HKK73_RS03085	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HKK73_RS03105	ENOG4108IJ6	ABC transporter
HKK73_RS03110	ENOG4105ECW	sulfate abc transporter
HKK73_RS03115	ENOG4108I5D	sulfate abc transporter
HKK73_RS03120	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HKK73_RS03130	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HKK73_RS03180	ENOG4105PGM	cation diffusion facilitator family transporter
HKK73_RS03185	ENOG4105CMR	udp-glucose 4-epimerase
HKK73_RS03195	ENOG4105EWK	phytoene
HKK73_RS03250	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HKK73_RS03260	ENOG4105CPQ	Dehydrogenase
HKK73_RS03295	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
HKK73_RS03340	ENOG4105C1J	atp-dependent rna helicase
HKK73_RS03345	ENOG4105E0X	reductase
HKK73_RS03355	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
HKK73_RS03390	ENOG4105CJ3	phosphate transporter
HKK73_RS03400	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HKK73_RS03405	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HKK73_RS03415	ENOG4105H3G	oxidoreductase
HKK73_RS03420	ENOG4105DXI	Major Facilitator superfamily
HKK73_RS03425	ENOG4105DDN	Pentapeptide repeat-containing protein
HKK73_RS03430	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HKK73_RS03485	ENOG4108R0M	Aminoglycoside
HKK73_RS03505	ENOG4108I5C	dEAD DEAH box helicase
HKK73_RS03515	ENOG4105DFM	M18 family aminopeptidase
HKK73_RS03525	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HKK73_RS03565	ENOG4106T9R	serine protease
HKK73_RS03575	ENOG4105E7D	Protein of unknown function (DUF3375)
HKK73_RS03585	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HKK73_RS03600	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HKK73_RS03605	ENOG4105DCT	glycerol dehydrogenase
HKK73_RS03630	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HKK73_RS03635	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HKK73_RS03650	ENOG4105K56	Transcriptional regulator
HKK73_RS03655	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
HKK73_RS03660	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HKK73_RS03755	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HKK73_RS03770	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HKK73_RS03775	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HKK73_RS03795	ENOG41080R8	Conserved Protein
HKK73_RS03805	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HKK73_RS03810	ENOG41073TP	transcriptional regulator
HKK73_RS03815	ENOG4105CHP	RNA polymerase
HKK73_RS03835	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HKK73_RS03845	ENOG4105CPC	Aldo Keto reductase
HKK73_RS03850	ENOG4105CHP	RNA polymerase
HKK73_RS03860	ENOG4108JQ7	(ABC) transporter
HKK73_RS03865	ENOG4105BZU	Histidine kinase
HKK73_RS03885	ENOG4105C4C	beta-galactosidase
HKK73_RS03905	ENOG4105ETE	Transcriptional regulator (LacI family
HKK73_RS03915	ENOG4105E2R	ROK family
HKK73_RS03920	ENOG4105C93	Xylose Isomerase
HKK73_RS03930	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HKK73_RS03935	ENOG4108JQ1	Dehydrogenase
HKK73_RS03955	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HKK73_RS03990	ENOG4108WYP	Transcriptional regulator
HKK73_RS04000	ENOG4105CHR	reductase
HKK73_RS04010	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HKK73_RS04035	ENOG4105CHR	reductase
HKK73_RS04040	ENOG4108JQ1	Dehydrogenase
HKK73_RS04050	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
HKK73_RS04055	ENOG4105C31	Tryptophanyl-tRNA synthetase
HKK73_RS04070	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
HKK73_RS04075	ENOG4105WBV	Transcriptional regulator
HKK73_RS04115	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HKK73_RS04120	ENOG4105BZU	Histidine kinase
HKK73_RS04135	ENOG4108VYJ	response regulator receiver protein
HKK73_RS04155	ENOG4105E1Q	flagellar hook-associated protein
HKK73_RS04165	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HKK73_RS04170	ENOG4105I03	Flagellin
HKK73_RS04175	ENOG4105I03	Flagellin
HKK73_RS04180	ENOG4105I03	Flagellin
HKK73_RS04200	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HKK73_RS04205	ENOG4108ZC9	flagellar basal-body rod protein flgc
HKK73_RS04210	ENOG41084Q6	flagellar hook-basal body complex protein fliE
HKK73_RS04215	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HKK73_RS04240	ENOG41068JE	domain protein
HKK73_RS04255	ENOG4105BZE	flagellar hook protein, FlgE
HKK73_RS04270	ENOG4106VK6	Flagellar motor protein
HKK73_RS04280	ENOG4105DD5	Flagellar motor switch protein
HKK73_RS04290	ENOG4105CN7	Flagellar biosynthetic protein FliP
HKK73_RS04295	ENOG4105VS8	Flagellar biosynthetic protein fliq
HKK73_RS04300	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HKK73_RS04305	ENOG4105D00	flagellar biosynthetic protein flhB
HKK73_RS04310	ENOG4105D7B	Flagellar biosynthesis protein flha
HKK73_RS04320	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HKK73_RS04340	ENOG41061ZR	Transcriptional regulator
HKK73_RS04340	ENOG41061ZR	Transcriptional regulator
HKK73_RS04360	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HKK73_RS04365	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HKK73_RS04370	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HKK73_RS04375	ENOG4105DKT	Transcriptional regulator
HKK73_RS04385	ENOG4105CEN	a g-specific adenine glycosylase
HKK73_RS04395	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HKK73_RS04400	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
HKK73_RS04405	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HKK73_RS04410	ENOG4105EYW	Ion transport protein
HKK73_RS04420	ENOG4105II7	pyrroline-5-carboxylate reductase
HKK73_RS04425	ENOG4105ETE	Transcriptional regulator (LacI family
HKK73_RS04435	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
HKK73_RS04440	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
HKK73_RS04445	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
HKK73_RS04450	ENOG4105C2J	ABC transporter
HKK73_RS04455	ENOG4107R9N	ABC transporter
HKK73_RS04460	ENOG41062B0	ABC transporter, permease
HKK73_RS04475	ENOG4105DSG	hydrolase family 43
HKK73_RS04485	ENOG4107SYN	Glycosyl hydrolases family 43
HKK73_RS04510	ENOG4107ZYR	domain protein
HKK73_RS04515	ENOG4105CZN	Potassium uptake protein
HKK73_RS04520	ENOG4105DGU	Histone deacetylase
HKK73_RS04540	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
HKK73_RS04555	ENOG4108RH7	phosphoglycerate mutase
HKK73_RS04565	ENOG4107QIV	Cytochrome c biogenesis protein
HKK73_RS04570	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
HKK73_RS04575	ENOG4105CRE	cytochrome C
HKK73_RS04590	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HKK73_RS04600	ENOG4108R5T	secreted protein
HKK73_RS04610	ENOG4107SIQ	Naphthoate synthase
HKK73_RS04620	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HKK73_RS04635	ENOG4107TCW	O-succinylbenzoate synthase
HKK73_RS04640	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HKK73_RS04650	ENOG4105E4F	Isochorismate synthase
HKK73_RS04655	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HKK73_RS04670	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HKK73_RS04680	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HKK73_RS04690	ENOG4107QIZ	NADH dehydrogenase
HKK73_RS04695	ENOG4108IEH	NADH dehydrogenase subunit g
HKK73_RS04700	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HKK73_RS04705	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HKK73_RS04715	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HKK73_RS04720	ENOG4105D65	subunit l
HKK73_RS04730	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HKK73_RS04745	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HKK73_RS04760	ENOG4108UW8	fha domain-containing protein
HKK73_RS04765	ENOG4108ZF3	Phosphatase
HKK73_RS04785	ENOG4105EC2	ftsk spoIIIe
HKK73_RS04805	ENOG4105D0M	Protease HtpX homolog
HKK73_RS04810	ENOG410667J	hydrolase
HKK73_RS04815	ENOG4108VPT	UPF0234 protein
HKK73_RS04840	ENOG4105WDJ	50S ribosomal protein L33
HKK73_RS04845	ENOG410900P	UPF0336 protein
HKK73_RS04850	ENOG4108F01	MaoC domain protein
HKK73_RS04870	ENOG4106UW1	Major Facilitator superfamily
HKK73_RS04875	ENOG4107R4N	Cell wall formation (By similarity)
HKK73_RS04885	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
HKK73_RS04905	ENOG4105ETX	regulatoR
HKK73_RS04920	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HKK73_RS04930	ENOG4108VB1	regulatoR
HKK73_RS04935	ENOG4105BZU	Histidine kinase
HKK73_RS04945	ENOG4105CJ1	ABC, transporter
HKK73_RS04965	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HKK73_RS04970	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HKK73_RS05010	ENOG4108VZM	50s ribosomal protein L10
HKK73_RS05015	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HKK73_RS05020	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HKK73_RS05025	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HKK73_RS05030	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HKK73_RS05035	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HKK73_RS05040	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HKK73_RS05045	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HKK73_RS05050	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HKK73_RS05055	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HKK73_RS05060	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HKK73_RS05065	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HKK73_RS05070	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKK73_RS05075	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HKK73_RS05080	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HKK73_RS05085	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HKK73_RS05090	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HKK73_RS05095	ENOG41082SA	50s ribosomal protein l29
HKK73_RS05100	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HKK73_RS05105	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HKK73_RS05110	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HKK73_RS05115	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKK73_RS05120	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HKK73_RS05125	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HKK73_RS05130	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HKK73_RS05135	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HKK73_RS05140	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HKK73_RS05150	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HKK73_RS05155	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HKK73_RS05160	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HKK73_RS05170	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HKK73_RS05175	ENOG41067V7	50S ribosomal protein L36
HKK73_RS05180	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKK73_RS05185	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HKK73_RS05190	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HKK73_RS05195	ENOG4108ZT0	50S ribosomal protein l17
HKK73_RS05205	ENOG4105DFK	Polyphosphate glucokinase
HKK73_RS05210	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HKK73_RS05225	ENOG4105C5H	ABC transporter
HKK73_RS05230	ENOG4105C72	UPF0176 protein
HKK73_RS05235	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HKK73_RS05240	ENOG4108UJD	30S ribosomal protein S9
HKK73_RS05250	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HKK73_RS05260	ENOG4105CS9	pantothenic acid kinase
HKK73_RS05275	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HKK73_RS05300	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HKK73_RS05305	ENOG4108097	ATP-binding protein
HKK73_RS05325	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
HKK73_RS05330	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HKK73_RS05335	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
HKK73_RS05345	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HKK73_RS05350	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HKK73_RS05360	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HKK73_RS05375	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HKK73_RS05385	ENOG4107QVP	Dehydrogenase
HKK73_RS05400	ENOG4105C26	Dehydrogenase
HKK73_RS05415	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HKK73_RS05425	ENOG4107QRI	Phosphoketolase
HKK73_RS05445	ENOG4105BZ1	(ABC) transporter
HKK73_RS05450	ENOG4105BZ1	(ABC) transporter
HKK73_RS05465	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HKK73_RS05475	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HKK73_RS05480	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HKK73_RS05485	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HKK73_RS05515	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS05520	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HKK73_RS05535	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HKK73_RS05540	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HKK73_RS05555	ENOG4108YIQ	Alpha beta hydrolase
HKK73_RS05575	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HKK73_RS05585	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HKK73_RS05625	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HKK73_RS05630	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
HKK73_RS05650	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HKK73_RS05675	ENOG4105CNN	ABC, transporter
HKK73_RS05680	ENOG4105DFW	ABC transporter
HKK73_RS05695	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HKK73_RS05700	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HKK73_RS05710	ENOG4105CGK	Exodeoxyribonuclease III
HKK73_RS05715	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HKK73_RS05720	ENOG4105E98	transcriptional regulator DeoR family
HKK73_RS05725	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HKK73_RS05730	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HKK73_RS05740	ENOG4105D1F	ATP-binding protein
HKK73_RS05755	ENOG4105CJW	magnesium transporter
HKK73_RS05765	ENOG4107T6F	Xaa-Pro aminopeptidase
HKK73_RS05775	ENOG4105DB7	PHP domain protein
HKK73_RS05780	ENOG41081FY	multiple antibiotic resistance (MarC)-related
HKK73_RS05790	ENOG41073TP	transcriptional regulator
HKK73_RS05795	ENOG4105DJ2	Major Facilitator Superfamily
HKK73_RS05800	ENOG4105C1J	atp-dependent rna helicase
HKK73_RS05860	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HKK73_RS05885	ENOG41063PX	domain protein
HKK73_RS05895	ENOG4105DJZ	UPF0182 protein
HKK73_RS05910	ENOG4106PMH	Extracellular solute-binding protein family 3
HKK73_RS05915	ENOG4105E5Q	amino acid AbC transporter
HKK73_RS05925	ENOG4105D9P	serine threonine protein kinase
HKK73_RS05930	ENOG4105C7Z	Conserved Protein
HKK73_RS05940	ENOG4108375	Acylphosphatase (EC 3.6.1.7)
HKK73_RS05955	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HKK73_RS05960	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HKK73_RS05965	ENOG4107Y2X	deaminase
HKK73_RS05970	ENOG4105C7N	Xanthine uracil vitamin C permease
HKK73_RS05990	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HKK73_RS05995	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HKK73_RS06005	ENOG4105C7W	Xanthine dehydrogenase
HKK73_RS06025	ENOG4105KVH	Transcriptional regulator
HKK73_RS06030	ENOG4105ECR	NmrA family
HKK73_RS06035	ENOG4105SHT	UspA domain-containing protein
HKK73_RS06040	ENOG4107HP6	Transcriptional regulator
HKK73_RS06045	ENOG4108UHU	Aldolase
HKK73_RS06050	ENOG4105D7K	pfkb domain protein
HKK73_RS06065	ENOG4105CHR	reductase
HKK73_RS06070	ENOG4105DHU	Bile acid
HKK73_RS06100	ENOG4107RR1	TRANSCRIPTIONal
HKK73_RS06105	ENOG4105C26	Dehydrogenase
HKK73_RS06120	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKK73_RS06130	ENOG4105KVH	Transcriptional regulator
HKK73_RS06140	ENOG4107R9S	Malate synthase
HKK73_RS06160	ENOG4105CHU	acetyl-coa acetyltransferase
HKK73_RS06165	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HKK73_RS06195	ENOG4105CEY	Amp-dependent synthetase and ligase
HKK73_RS06205	ENOG4105C32	Amino acid ABC transporter (Permease)
HKK73_RS06210	ENOG4108IV0	ABC, transporter
HKK73_RS06215	ENOG4105C0Z	ABC transporter
HKK73_RS06230	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HKK73_RS06255	ENOG4108IAB	Phoh family
HKK73_RS06270	ENOG4105C9Q	fumarate hydratase class II
HKK73_RS06300	ENOG4105D7K	pfkb domain protein
HKK73_RS06305	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HKK73_RS06310	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HKK73_RS06320	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HKK73_RS06340	ENOG4105C3G	gtp-binding protein
HKK73_RS06355	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HKK73_RS06375	ENOG4105CI3	gtp-binding protein typa
HKK73_RS06380	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HKK73_RS06405	ENOG4105EVN	Prephenate dehydrogenase
HKK73_RS06415	ENOG4108Z4U	Ferredoxin
HKK73_RS06440	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
HKK73_RS06445	ENOG4108URH	decarboxylase
HKK73_RS06450	ENOG4105EEI	dihydropteroate synthase
HKK73_RS06465	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HKK73_RS06475	ENOG4105DU6	RNA polymerase
HKK73_RS06485	ENOG4105C0H	protease
HKK73_RS06495	ENOG4105C31	Tryptophanyl-tRNA synthetase
HKK73_RS06510	ENOG4105E33	succinate dehydrogenase
HKK73_RS06535	ENOG4107RM1	amidohydrolase
HKK73_RS06540	ENOG4105DIH	basic membrane
HKK73_RS06545	ENOG4108JQ9	ABC transporter
HKK73_RS06550	ENOG4105UIB	(ABC) transporter
HKK73_RS06570	ENOG4105VG5	Membrane
HKK73_RS06590	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HKK73_RS06595	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HKK73_RS06600	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
HKK73_RS06615	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HKK73_RS06630	ENOG4108JW7	Maf-like protein
HKK73_RS06640	ENOG4108JIK	carboxylase
HKK73_RS06645	ENOG4107WR6	Maf-like protein
HKK73_RS06650	ENOG4105RK9	auxin efflux carrier
HKK73_RS06675	ENOG4105D8K	carboxyl transferase
HKK73_RS06690	ENOG4108RAV	Conserved protein
HKK73_RS06695	ENOG4105C2C	drug resistance transporter, Bcr CflA
HKK73_RS06700	ENOG4108KGH	TRANSCRIPTIONal
HKK73_RS06850	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
HKK73_RS06855	ENOG4105CAK	Cell division ATP-binding protein ftsE
HKK73_RS06860	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
HKK73_RS06865	ENOG41063SB	peptidase
HKK73_RS06870	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HKK73_RS06900	ENOG4105E2R	ROK family
HKK73_RS06920	ENOG4105DKQ	ROK family
HKK73_RS06925	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HKK73_RS06945	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HKK73_RS06955	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HKK73_RS06960	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HKK73_RS06965	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HKK73_RS06970	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HKK73_RS07000	ENOG4105CVK	Glutamate decarboxylase
HKK73_RS07010	ENOG41080RH	Thioredoxin
HKK73_RS07040	ENOG41088CQ	domain protein
HKK73_RS07045	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HKK73_RS07050	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HKK73_RS07055	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HKK73_RS07065	ENOG4107QN1	sodium solute
HKK73_RS07085	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
HKK73_RS07090	ENOG4105E90	ABC transporter
HKK73_RS07095	ENOG4105E90	ABC transporter
HKK73_RS07100	ENOG4108IJ8	ABC transporter
HKK73_RS07105	ENOG410829K	Lysine exporter protein (Lyse ygga)
HKK73_RS07115	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HKK73_RS07125	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HKK73_RS07140	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
HKK73_RS07145	ENOG4108JJB	ABC transporter
HKK73_RS07155	ENOG4107F3J	Amp-dependent synthetase and ligase
HKK73_RS07160	ENOG4107ZYJ	bioY protein
HKK73_RS07170	ENOG4105Q36	FHA domain containing protein
HKK73_RS07195	ENOG4105CT1	(ABC) transporter
HKK73_RS07205	ENOG4106F1P	AAA ATPase, central domain protein
HKK73_RS07235	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HKK73_RS07245	ENOG4105VHU	single-stranded DNA-binding protein
HKK73_RS07275	ENOG4105CGD	Nad-dependent epimerase dehydratase
HKK73_RS07285	ENOG4105C29	acyl-CoA thioesterase
HKK73_RS07295	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HKK73_RS07305	ENOG4105D8X	mechanosensitive ion channel
HKK73_RS07320	ENOG4105MC2	DSBA oxidoreductase
HKK73_RS07330	ENOG4105C9K	Endothelin-converting enzyme 1
HKK73_RS07335	ENOG4108YZG	isomerase
HKK73_RS07355	ENOG4105DYW	oxidoreductase
HKK73_RS07360	ENOG4105D7W	serine acetyltransferase
HKK73_RS07385	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HKK73_RS07390	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HKK73_RS07395	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HKK73_RS07400	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HKK73_RS07410	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
HKK73_RS07430	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HKK73_RS07435	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
HKK73_RS07450	ENOG4105DSF	transport protein
HKK73_RS07485	ENOG4105K4P	CoA-binding domain protein
HKK73_RS07495	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HKK73_RS07500	ENOG4105EHG	Permease protein
HKK73_RS07515	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HKK73_RS07525	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HKK73_RS07530	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HKK73_RS07535	ENOG4105CMT	Dihydroxyacetone kinase
HKK73_RS07540	ENOG4108UTZ	Dihydroxyacetone kinase
HKK73_RS07555	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HKK73_RS07565	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HKK73_RS07580	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKK73_RS07595	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HKK73_RS07610	ENOG4105K5M	30s ribosomal protein S16
HKK73_RS07615	ENOG41082KU	UPF0109 protein
HKK73_RS07620	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HKK73_RS07625	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HKK73_RS07630	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HKK73_RS07635	ENOG4107QYR	Signal peptidase i
HKK73_RS07640	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HKK73_RS07650	ENOG41080R2	UPF0102 protein
HKK73_RS07665	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HKK73_RS07675	ENOG4105CE9	30S ribosomal protein S2
HKK73_RS07680	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HKK73_RS07685	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HKK73_RS07690	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HKK73_RS07695	ENOG4105KNE	Phosphatidate cytidylyltransferase
HKK73_RS07700	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HKK73_RS07715	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HKK73_RS07720	ENOG4105DZP	Membrane-associated zinc metalloprotease
HKK73_RS07725	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HKK73_RS07740	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HKK73_RS07750	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
HKK73_RS07765	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HKK73_RS07770	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HKK73_RS07775	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HKK73_RS07795	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HKK73_RS07810	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS07820	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HKK73_RS07825	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HKK73_RS07830	ENOG4105C1V	Peptidase, M16
HKK73_RS07835	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HKK73_RS07880	ENOG4105CN5	Metallo-Beta-Lactamase
HKK73_RS07910	ENOG4107QZI	cell division protein FtsK
HKK73_RS07920	ENOG4105CEV	competence damage-inducible protein
HKK73_RS07925	ENOG4105WBV	Transcriptional regulator
HKK73_RS07930	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
HKK73_RS07935	ENOG4107QRT	dEAD DEAH box helicase
HKK73_RS07955	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HKK73_RS07960	ENOG4105KC9	Modulates RecA activity (By similarity)
HKK73_RS07965	ENOG4105DRP	amino acid AbC transporter
HKK73_RS07970	ENOG4108Q1T	ABC transporter
HKK73_RS07975	ENOG4107UBR	Extracellular solute-binding protein family 3
HKK73_RS07980	ENOG4105CDA	abc transporter atp-binding protein
HKK73_RS07985	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HKK73_RS08010	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HKK73_RS08020	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HKK73_RS08025	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HKK73_RS08030	ENOG4107Y49	methyltransferase
HKK73_RS08035	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HKK73_RS08050	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HKK73_RS08060	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HKK73_RS08065	ENOG4105CPC	Aldo Keto reductase
HKK73_RS08080	ENOG4108JQ1	Dehydrogenase
HKK73_RS08090	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HKK73_RS08095	ENOG4105BZU	Histidine kinase
HKK73_RS08110	ENOG4105VEQ	Cold shock protein
HKK73_RS08145	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HKK73_RS08150	ENOG4108V6E	Cell division protein mraZ
HKK73_RS08155	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HKK73_RS08165	ENOG4105CJN	penicillin-binding protein
HKK73_RS08170	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HKK73_RS08180	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HKK73_RS08185	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HKK73_RS08195	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HKK73_RS08200	ENOG4105DFU	Cell wall formation (By similarity)
HKK73_RS08210	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HKK73_RS08215	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HKK73_RS08220	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
HKK73_RS08255	ENOG4105C0B	DNA polymerase III (alpha subunit)
HKK73_RS08270	ENOG4105WQ3	Rna-binding protein
HKK73_RS08275	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HKK73_RS08285	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HKK73_RS08295	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HKK73_RS08300	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HKK73_RS08310	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HKK73_RS08315	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HKK73_RS08330	ENOG4105C0H	protease
HKK73_RS08345	ENOG4105CH6	catalase
HKK73_RS08355	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HKK73_RS08360	ENOG41084BS	50S ribosomal protein L35
HKK73_RS08365	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HKK73_RS08370	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HKK73_RS08380	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HKK73_RS08385	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HKK73_RS08400	ENOG4105DWF	phosphomethylpyrimidine kinase
HKK73_RS08425	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HKK73_RS08430	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HKK73_RS08435	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HKK73_RS08440	ENOG4105CAS	nag kinase
HKK73_RS08445	ENOG4105C8Y	Acetylornithine aminotransferase
HKK73_RS08455	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HKK73_RS08460	ENOG4105CDH	Citrulline--aspartate ligase
HKK73_RS08465	ENOG4105CH7	arginosuccinase
HKK73_RS08475	ENOG4108VX5	3-methyladenine DNA glycosylase
HKK73_RS08480	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HKK73_RS08525	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HKK73_RS08550	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HKK73_RS08575	ENOG4105CJ1	ABC, transporter
HKK73_RS08590	ENOG4105JRK	feS assembly protein SufD
HKK73_RS08595	ENOG4105VQD	rieske 2fe-2S domain-containing protein
HKK73_RS08600	ENOG4105C3K	feS assembly ATPase SufC
HKK73_RS08610	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HKK73_RS08615	ENOG4105VG1	fes assembly suf system protein
HKK73_RS08625	ENOG4107QZF	nitrite reductase NADPH large subunit
HKK73_RS08630	ENOG4107QZF	nitrite reductase NADPH large subunit
HKK73_RS08650	ENOG4108UW5	maltose o-acetyltransferase
HKK73_RS08670	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HKK73_RS08690	ENOG4107W53	thymidine kinase
HKK73_RS08700	ENOG4105EN6	Membrane
HKK73_RS08720	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HKK73_RS08745	ENOG4107VEG	TrkA-N domain protein
HKK73_RS08750	ENOG4105C0X	amino acid
HKK73_RS08755	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HKK73_RS08765	ENOG4107QM5	aconitate hydratase
HKK73_RS08790	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
HKK73_RS08800	ENOG4105F1A	Pyruvate formate-lyase
HKK73_RS08805	ENOG4105RHY	Pfam:UPF0157
HKK73_RS08825	ENOG4107W19	lmbE family
HKK73_RS08830	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HKK73_RS08845	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HKK73_RS08855	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HKK73_RS08890	ENOG4105CSR	polyphosphate kinase 2
HKK73_RS09000	ENOG4105C22	threonyL-tRNA synthetase
HKK73_RS09020	ENOG4105E2K	Glycosyl transferase (Group 1
HKK73_RS09030	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
HKK73_RS09035	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HKK73_RS09045	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
HKK73_RS09050	ENOG4105CDY	transcriptional regulatory protein
HKK73_RS09055	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HKK73_RS09060	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HKK73_RS09065	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HKK73_RS09075	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HKK73_RS09080	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HKK73_RS09085	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HKK73_RS09090	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HKK73_RS09100	ENOG4105DQE	DNA ligase
HKK73_RS09110	ENOG4105C99	atpase involved in dna repair
HKK73_RS09120	ENOG4105C5X	domain protein
HKK73_RS09125	ENOG4105CUT	histidyl-tRNA synthetase
HKK73_RS09140	ENOG4108JJB	ABC transporter
HKK73_RS09145	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
HKK73_RS09165	ENOG4105C9M	aspartyl-trna synthetase
HKK73_RS09180	ENOG4108KXV	response regulator
HKK73_RS09185	ENOG4107R13	MMPL domain protein
HKK73_RS09195	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HKK73_RS09210	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HKK73_RS09215	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HKK73_RS09225	ENOG4105E2X	shikimate dehydrogenase
HKK73_RS09235	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HKK73_RS09240	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HKK73_RS09245	ENOG4105D49	3-dehydroquinate synthase
HKK73_RS09255	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HKK73_RS09270	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HKK73_RS09275	ENOG410803B	Involved in the transcription termination process (By similarity)
HKK73_RS09280	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HKK73_RS09285	ENOG4105CXT	aspartate transcarbamylase
HKK73_RS09290	ENOG4105CD3	dihydroorotase
HKK73_RS09300	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HKK73_RS09305	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HKK73_RS09310	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HKK73_RS09320	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HKK73_RS09325	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HKK73_RS09330	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HKK73_RS09340	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HKK73_RS09345	ENOG4107RSZ	Primosomal protein n'
HKK73_RS09360	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HKK73_RS09385	ENOG4105DJV	ribulose-phosphate 3-epimerase
HKK73_RS09400	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HKK73_RS09405	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HKK73_RS09410	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
HKK73_RS09415	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HKK73_RS09450	ENOG4108UW8	fha domain-containing protein
HKK73_RS09470	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
HKK73_RS09475	ENOG4105E8R	UPF0173 metal-dependent hydrolase
HKK73_RS09480	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HKK73_RS09550	ENOG4108UZX	fmn reductase
HKK73_RS09555	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HKK73_RS09560	ENOG4105Q70	
HKK73_RS09565	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HKK73_RS09575	ENOG4105CI2	imidazolone-5-propionate hydrolase
HKK73_RS09585	ENOG4105CBD	Diacylglycerol kinase
HKK73_RS09590	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HKK73_RS09610	ENOG4108FFZ	Transcriptional regulator
HKK73_RS09625	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HKK73_RS09640	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
HKK73_RS09655	ENOG4105CDH	Citrulline--aspartate ligase
HKK73_RS09660	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HKK73_RS09675	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HKK73_RS09735	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
HKK73_RS09800	ENOG4107RSM	transcriptional regulator
HKK73_RS09825	ENOG4107TXC	Transcriptional regulator
HKK73_RS09835	ENOG4107S6X	Glycosyl transferase, family 2
HKK73_RS09875	ENOG4105D74	hydrolase
HKK73_RS09900	ENOG4105CSV	Glutaminase
HKK73_RS09950	ENOG4107R3N	Filamentation induced by cAMP protein fic
HKK73_RS09975	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HKK73_RS09985	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HKK73_RS10005	ENOG4105CAT	Cytidine monophosphate kinase
HKK73_RS10020	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HKK73_RS10025	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HKK73_RS10040	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HKK73_RS10050	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HKK73_RS10065	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
HKK73_RS10085	ENOG4105CP7	Triose-phosphate isomerase
HKK73_RS10090	ENOG4105BZA	Phosphoglycerate kinase
HKK73_RS10100	ENOG4105CIE	May be required for sporulation (By similarity)
HKK73_RS10110	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HKK73_RS10115	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HKK73_RS10130	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HKK73_RS10150	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HKK73_RS10160	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
HKK73_RS10165	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HKK73_RS10175	ENOG4105BZ1	(ABC) transporter
HKK73_RS10180	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HKK73_RS10200	ENOG4108TZA	Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity)
HKK73_RS10230	ENOG410756H	nucleotidyltransferase
HKK73_RS10245	ENOG4105CBC	glutamate synthase
HKK73_RS10250	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HKK73_RS10255	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HKK73_RS10260	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HKK73_RS10265	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HKK73_RS10295	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HKK73_RS10300	ENOG4105BZ1	(ABC) transporter
HKK73_RS10305	ENOG4105BZ1	(ABC) transporter
HKK73_RS10310	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HKK73_RS10315	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HKK73_RS10320	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
HKK73_RS10325	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
HKK73_RS10330	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
HKK73_RS10335	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
HKK73_RS10340	ENOG4105E5F	proteasome
HKK73_RS10345	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
HKK73_RS10360	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HKK73_RS10375	ENOG4105C8N	cysteinyl-tRNA synthetase
HKK73_RS10380	ENOG4105D7N	magnesium and cobalt transport protein CorA
HKK73_RS10385	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HKK73_RS10390	ENOG4105CPC	Aldo Keto reductase
HKK73_RS10410	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HKK73_RS10415	ENOG4105E3B	Multicopper oxidase
HKK73_RS10430	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS10435	ENOG4105DGW	oligopeptidase A
HKK73_RS10515	ENOG4105BZU	Histidine kinase
HKK73_RS10520	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS10570	ENOG4105DG4	malate L-lactate dehydrogenase
HKK73_RS10595	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HKK73_RS10600	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
HKK73_RS10655	ENOG4105WEF	catalase
HKK73_RS10665	ENOG4107FW0	short-chain dehydrogenase reductase
HKK73_RS10710	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
HKK73_RS10715	ENOG4105C26	Dehydrogenase
HKK73_RS10725	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HKK73_RS10730	ENOG4105DKP	glycosyl transferase, family 9
HKK73_RS10740	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HKK73_RS10745	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HKK73_RS10760	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HKK73_RS10770	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HKK73_RS10775	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HKK73_RS10780	ENOG4107RY6	amino acid
HKK73_RS10785	ENOG4105ETE	Transcriptional regulator (LacI family
HKK73_RS10795	ENOG4108RVA	ribokinase
HKK73_RS10820	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HKK73_RS10825	ENOG4105BZU	Histidine kinase
HKK73_RS10830	ENOG4105E0Y	RtcB Protein
HKK73_RS10850	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HKK73_RS10860	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HKK73_RS10875	ENOG4105C0B	DNA polymerase III (alpha subunit)
HKK73_RS10895	ENOG4105EEM	helicase
HKK73_RS10905	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
HKK73_RS10910	ENOG4105J76	Periplasmic binding protein
HKK73_RS10915	ENOG4105E0A	ABC, transporter
HKK73_RS10985	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HKK73_RS10995	ENOG4105VPX	protein, conserved in bacteria
HKK73_RS11025	ENOG4105DKW	ABC transporter
HKK73_RS11040	ENOG4107QPH	glycogen) synthase
HKK73_RS11045	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HKK73_RS11050	ENOG4105EAC	phosphoserine phosphatase
HKK73_RS11055	ENOG4105M4E	phosphohistidine phosphatase, SixA
HKK73_RS11065	ENOG4105CHR	reductase
HKK73_RS11085	ENOG4105C5H	ABC transporter
HKK73_RS11110	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HKK73_RS11115	ENOG4105C3R	Methionine synthase
HKK73_RS11130	ENOG4105VMP	Transcriptional regulator
HKK73_RS11165	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HKK73_RS11180	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HKK73_RS11185	ENOG4105SHT	UspA domain-containing protein
HKK73_RS11215	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
HKK73_RS11235	ENOG4105DKQ	ROK family
HKK73_RS11260	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HKK73_RS11270	ENOG4105CCU	oxidase (Subunit III)
HKK73_RS11275	ENOG4107UDY	cytochrome C
HKK73_RS11280	ENOG4107EUI	c reductase, iron-sulfur
HKK73_RS11285	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HKK73_RS11295	ENOG4105MCD	Part of cytochrome c oxidase, its function is
HKK73_RS11300	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HKK73_RS11305	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HKK73_RS11310	ENOG4107QI6	Cysteine desulfurase
HKK73_RS11315	ENOG4105VFE	sira family
HKK73_RS11335	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HKK73_RS11345	ENOG4105EYF	MMPL domain protein
HKK73_RS11355	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HKK73_RS11365	ENOG4105CPC	Aldo Keto reductase
HKK73_RS11385	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HKK73_RS11400	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HKK73_RS11420	ENOG4105ECP	epimerase
HKK73_RS11430	ENOG4105D9R	oxidoreductase
HKK73_RS11445	ENOG4105K56	Transcriptional regulator
HKK73_RS11450	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HKK73_RS11460	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HKK73_RS11475	ENOG4105C5F	glutamine synthetase
HKK73_RS11485	ENOG4107S2E	monooxygenase
HKK73_RS11490	ENOG4107QWE	)-transporter
HKK73_RS11500	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HKK73_RS11505	ENOG4105C5F	glutamine synthetase
HKK73_RS11510	ENOG4105C4K	Nad synthetase
HKK73_RS11515	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HKK73_RS11525	ENOG4108RU2	n-acetylmuramoyl-l-alanine amidase
HKK73_RS11550	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HKK73_RS11555	ENOG4105DWF	phosphomethylpyrimidine kinase
HKK73_RS11575	ENOG4105EEM	helicase
HKK73_RS11575	ENOG4105EEM	helicase
HKK73_RS11580	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HKK73_RS11590	ENOG4107XFJ	UPF0246 protein
HKK73_RS11610	ENOG4105EGD	dinuclear metal center protein, YbgI family
HKK73_RS11620	ENOG4105CHH	sulfate transporter
HKK73_RS11635	ENOG4105C2M	dna polymerase I
HKK73_RS11645	ENOG4105DEG	Vwa containing coxe family protein
HKK73_RS11650	ENOG4105RD5	
HKK73_RS11655	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
HKK73_RS11665	ENOG4108KDT	Molybdate metabolism regulator
HKK73_RS11715	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HKK73_RS11735	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HKK73_RS11740	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HKK73_RS11745	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HKK73_RS11755	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HKK73_RS11795	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HKK73_RS11810	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HKK73_RS11820	ENOG4107R28	alpha amylase, catalytic region
HKK73_RS11825	ENOG4105EG2	ABC transporter, permease
HKK73_RS11830	ENOG4105D56	permease protein
HKK73_RS11840	ENOG4105ETE	Transcriptional regulator (LacI family
HKK73_RS11845	ENOG4105CG3	alpha amylase, catalytic region
HKK73_RS11860	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
HKK73_RS11865	ENOG4105DSE	periplasmic solute binding protein
HKK73_RS11870	ENOG4105DIK	(ABC) transporter
HKK73_RS11900	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HKK73_RS11905	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
HKK73_RS11925	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HKK73_RS11945	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HKK73_RS11955	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HKK73_RS11965	ENOG4107YU2	histidine triad (hIT) protein
HKK73_RS11975	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HKK73_RS11980	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HKK73_RS12005	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HKK73_RS12020	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HKK73_RS12035	ENOG4105BZM	domain protein
HKK73_RS12040	ENOG4105EPR	degv family
HKK73_RS12050	ENOG41064MX	Tetr family transcriptional regulator
HKK73_RS12055	ENOG4105D7A	ATP-binding protein
HKK73_RS12060	ENOG4105C8T	Leucyl-tRNA synthetase
HKK73_RS12065	ENOG41082VC	UPF0145 protein
HKK73_RS12075	ENOG4105F27	Major Facilitator
HKK73_RS12095	ENOG4105C57	major facilitator superfamily
HKK73_RS12115	ENOG4105FDF	Could be involved in DNA repair (By similarity)
HKK73_RS12130	ENOG4105DQE	DNA ligase
HKK73_RS12140	ENOG4105CD3	dihydroorotase
HKK73_RS12150	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HKK73_RS12155	ENOG41082W1	Cupin 2, conserved barrel domain protein
HKK73_RS12170	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HKK73_RS12180	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HKK73_RS12190	ENOG4105DWT	malate dehydrogenase (quinone)
HKK73_RS12230	ENOG4107QM2	Aldo Keto reductase
HKK73_RS12265	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HKK73_RS12275	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HKK73_RS12285	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HKK73_RS12290	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HKK73_RS12295	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKK73_RS12300	ENOG4105K46	50S ribosomal protein l27
HKK73_RS12305	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HKK73_RS12315	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HKK73_RS12320	ENOG4107T8J	thymidine kinase
HKK73_RS12330	ENOG4105C03	ribonuclease
HKK73_RS12335	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HKK73_RS12340	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HKK73_RS12345	ENOG4108JJ9	ABC, transporter
HKK73_RS12350	ENOG4105BZ1	(ABC) transporter
HKK73_RS12365	ENOG4105E5D	amino acid
HKK73_RS12370	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HKK73_RS12375	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HKK73_RS12380	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HKK73_RS12385	ENOG41084BZ	50S ribosomal protein L32
HKK73_RS12400	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HKK73_RS12410	ENOG4106H78	methyltransferase
HKK73_RS12415	ENOG4105CB5	ATP-dependent DNA helicase recG
HKK73_RS12420	ENOG4105DP4	dak2 domain fusion protein ylov
HKK73_RS12425	ENOG4105VB9	50S ribosomal protein l28
HKK73_RS12445	ENOG4105CPF	Cell wall formation (By similarity)
HKK73_RS12485	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HKK73_RS12495	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS12500	ENOG4108ZGX	Histidine kinase
HKK73_RS12505	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HKK73_RS12510	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HKK73_RS12515	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HKK73_RS12535	ENOG4105C8T	Leucyl-tRNA synthetase
HKK73_RS12540	ENOG4105CKW	Inner membrane protein yedI
HKK73_RS12550	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HKK73_RS12555	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HKK73_RS12560	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HKK73_RS12565	ENOG41069M3	Transcriptional regulator
HKK73_RS12605	ENOG4107ZR7	Membrane
HKK73_RS12615	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HKK73_RS12625	ENOG4105ERH	Fumarylacetoacetate hydrolase
HKK73_RS12640	ENOG4105CPC	Aldo Keto reductase
HKK73_RS12755	ENOG4108Z66	YbaK ebsC protein
HKK73_RS12765	ENOG4105DFA	alanine racemase domain protein
HKK73_RS12770	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKK73_RS12775	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HKK73_RS12780	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HKK73_RS12800	ENOG4105DF9	Lipoate-protein, ligase
HKK73_RS12805	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HKK73_RS12815	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HKK73_RS12820	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HKK73_RS12825	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
HKK73_RS12835	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HKK73_RS12840	ENOG4108ZP8	Acetolactate synthase small subunit
HKK73_RS12875	ENOG4105CKK	Glycosyl transferase, family 2
HKK73_RS12885	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HKK73_RS12895	ENOG4108ZCD	Transcriptional coactivator pterin dehydratase
HKK73_RS12900	ENOG4105C01	Dihydroxy-acid dehydratase
HKK73_RS12910	ENOG4105C01	Dihydroxy-acid dehydratase
HKK73_RS12920	ENOG4105DUX	Transporter
HKK73_RS12925	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HKK73_RS12945	ENOG41060W2	glyoxylate carboligase
HKK73_RS12950	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HKK73_RS12955	ENOG4107TFQ	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HKK73_RS12960	ENOG4105S0E	allantoin catabolism protein
HKK73_RS12970	ENOG4107R9S	Malate synthase
HKK73_RS12980	ENOG41069M3	Transcriptional regulator
HKK73_RS13010	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HKK73_RS13015	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HKK73_RS13020	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HKK73_RS13040	ENOG4107R7A	Allophanate hydrolase subunit 2
HKK73_RS13045	ENOG4105E7W	lamb ycsf family protein
HKK73_RS13065	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
HKK73_RS13075	ENOG4105CNN	ABC, transporter
HKK73_RS13080	ENOG4108HWV	)-transporter
HKK73_RS13085	ENOG4105C2J	ABC transporter
HKK73_RS13090	ENOG4107TYG	Oxidoreductase domain-containing protein
HKK73_RS13115	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HKK73_RS13120	ENOG4105CNN	ABC, transporter
HKK73_RS13125	ENOG4105C2J	ABC transporter
HKK73_RS13130	ENOG4105DKQ	ROK family
HKK73_RS13150	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HKK73_RS13165	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS13180	ENOG4105C0A	alcohol dehydrogenase
HKK73_RS13210	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HKK73_RS13230	ENOG4105C10	Electron transfer flavoprotein
HKK73_RS13235	ENOG4105BZJ	Electron transfer flavoprotein
HKK73_RS13265	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
HKK73_RS13275	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
HKK73_RS13300	ENOG4107QKS	N-acylglucosamine 2-epimerase
HKK73_RS13310	ENOG4105EG2	ABC transporter, permease
HKK73_RS13325	ENOG4105ETE	Transcriptional regulator (LacI family
HKK73_RS13330	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HKK73_RS13360	ENOG4107S9D	Alpha beta hydrolase
HKK73_RS13375	ENOG41081K0	peptidylprolyl cis-trans isomerase
HKK73_RS13380	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HKK73_RS13385	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HKK73_RS13395	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HKK73_RS13400	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
HKK73_RS13415	ENOG4105CJQ	hydrolase, family 31
HKK73_RS13425	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
HKK73_RS13430	ENOG4108JP0	extracellular solute-binding protein family 1
HKK73_RS13435	ENOG4105ETE	Transcriptional regulator (LacI family
HKK73_RS13440	ENOG4105CE4	GlcNAc 6-P deacetylase
HKK73_RS13445	ENOG4105PMW	Domain of unknown function (DUF1990)
HKK73_RS13460	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
HKK73_RS13470	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HKK73_RS13475	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HKK73_RS13480	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HKK73_RS13485	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HKK73_RS13490	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HKK73_RS13505	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
HKK73_RS13520	ENOG4107UIY	sua5 ycio yrdc ywlc family protein
HKK73_RS13525	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HKK73_RS13530	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HKK73_RS13535	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HKK73_RS13545	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HKK73_RS13550	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
HKK73_RS13555	ENOG4105D6E	homoserine dehydrogenase
HKK73_RS13560	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HKK73_RS13565	ENOG4105C75	arginyL-tRNA synthetase
HKK73_RS13595	ENOG4105C37	(CBS) domain
HKK73_RS13600	ENOG4108PYU	two-component system response regulator
HKK73_RS13605	ENOG4105EB3	Histidine kinase
HKK73_RS13610	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HKK73_RS13660	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HKK73_RS13670	ENOG4107TK4	histidinol-phosphate phosphatase
HKK73_RS13710	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HKK73_RS13715	ENOG4105T0Z	Conserved Protein
HKK73_RS13720	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
HKK73_RS13730	ENOG4108T3R	lipoprotein lpqB
HKK73_RS13735	ENOG4105BZU	Histidine kinase
HKK73_RS13740	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HKK73_RS13755	ENOG4108WQ6	secreted protein
HKK73_RS13760	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HKK73_RS13790	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS13815	ENOG4108HQS	Glycine betaine
HKK73_RS13835	ENOG410602S	Transferase
HKK73_RS13850	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HKK73_RS13860	ENOG4105W49	UPF0434 protein
HKK73_RS13865	ENOG4107QKV	phosphomannomutase
HKK73_RS13890	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HKK73_RS13900	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HKK73_RS13910	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HKK73_RS13915	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HKK73_RS13950	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HKK73_RS13995	ENOG4107TB5	TRANSCRIPTIONal
HKK73_RS14000	ENOG4108KGH	TRANSCRIPTIONal
HKK73_RS14005	ENOG4105EXC	Acyl-transferase
HKK73_RS14020	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HKK73_RS14035	ENOG41065SU	Two-component system sensor kinase
HKK73_RS14040	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HKK73_RS14045	ENOG4105BZU	Histidine kinase
HKK73_RS14050	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS14055	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HKK73_RS14110	ENOG4105ETE	Transcriptional regulator (LacI family
HKK73_RS14120	ENOG4105C26	Dehydrogenase
HKK73_RS14130	ENOG4105CV8	reductase
HKK73_RS14135	ENOG4105D82	Glutamate dehydrogenase
HKK73_RS14145	ENOG4107JTW	chlorite dismutase
HKK73_RS14150	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HKK73_RS14165	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
HKK73_RS14175	ENOG4105BZ7	extracellular solute-binding protein family 1
HKK73_RS14180	ENOG4105CG3	alpha amylase, catalytic region
HKK73_RS14190	ENOG4105E2D	ec 3.2.1.52
HKK73_RS14205	ENOG4105KME	endoribonuclease L-psp
HKK73_RS14215	ENOG4105BZW	Glycerate kinase
HKK73_RS14225	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HKK73_RS14245	ENOG4105T1M	mycothiol conjugate amidase mca
HKK73_RS14255	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HKK73_RS14260	ENOG4105C7B	Threonine dehydratase
HKK73_RS14275	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HKK73_RS14280	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HKK73_RS14305	ENOG4105MHT	Transcriptional regulator, ARSR family
HKK73_RS14330	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HKK73_RS14380	ENOG4105BZU	Histidine kinase
HKK73_RS14385	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS14430	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HKK73_RS14435	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HKK73_RS14445	ENOG4105WBV	Transcriptional regulator
HKK73_RS14450	ENOG4105ETU	transcriptional activator (TenA
HKK73_RS14455	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
HKK73_RS14495	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HKK73_RS14520	ENOG4105KJF	protein tyrosine phosphatase
HKK73_RS14535	ENOG4107YJ4	chain length determinant protein
HKK73_RS14565	ENOG4107Y2G	Glycosyl transferase (Group 1
HKK73_RS14590	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HKK73_RS14595	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HKK73_RS14610	ENOG4105MPN	Membrane
HKK73_RS14620	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HKK73_RS14625	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HKK73_RS14635	ENOG41067SE	Tetr family transcriptional regulator
HKK73_RS14645	ENOG4108IUX	(ABC) transporter
HKK73_RS14650	ENOG4105RHA	ABC transporter, permease
HKK73_RS14655	ENOG4105K56	Transcriptional regulator
HKK73_RS14660	ENOG4105DJ2	Major Facilitator Superfamily
HKK73_RS14695	ENOG4105C5H	ABC transporter
HKK73_RS14735	ENOG4105I82	acetyl xylan esterase
HKK73_RS14740	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HKK73_RS14745	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HKK73_RS14750	ENOG4106839	domain protein
HKK73_RS14770	ENOG4105F8V	Hydrolase, tatD family
HKK73_RS14775	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HKK73_RS14785	ENOG4105D8V	Glucose sorbosone dehydrogenase
HKK73_RS14790	ENOG4108QIU	Dehydrogenase
HKK73_RS14795	ENOG4105CHM	Aminotransferase
HKK73_RS14805	ENOG4108RWI	nicotinamidase
HKK73_RS14825	ENOG4105E2D	ec 3.2.1.52
HKK73_RS14840	ENOG4105E6M	Sulphatase-modifying factor protein
HKK73_RS14865	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HKK73_RS14875	ENOG4105CUJ	penicillin amidase
HKK73_RS14890	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HKK73_RS14960	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HKK73_RS14985	ENOG4105CIK	Amidinotransferase
HKK73_RS14990	ENOG4105C8Y	Acetylornithine aminotransferase
HKK73_RS14995	ENOG4105XT2	Transcriptional regulator
HKK73_RS15025	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HKK73_RS15030	ENOG4107SFI	Major Facilitator superfamily
HKK73_RS15050	ENOG4108KGH	TRANSCRIPTIONal
HKK73_RS15065	ENOG4108KGH	TRANSCRIPTIONal
HKK73_RS15080	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HKK73_RS15110	ENOG4105EIP	mannose-6-phosphate isomerase
HKK73_RS15115	ENOG4105C7N	Xanthine uracil vitamin C permease
HKK73_RS15125	ENOG4105D3Q	Sugar transferase
HKK73_RS15145	ENOG4105VEQ	Cold shock protein
HKK73_RS15170	ENOG4105CFI	type iii restriction protein res subunit
HKK73_RS15180	ENOG41087YS	Phage shock protein A
HKK73_RS15200	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HKK73_RS15205	ENOG4105BZU	Histidine kinase
HKK73_RS15220	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HKK73_RS15250	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HKK73_RS15275	ENOG4108762	serine threonine protein kinase
HKK73_RS15280	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
HKK73_RS15310	ENOG4105C8N	cysteinyl-tRNA synthetase
HKK73_RS15335	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HKK73_RS15340	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HKK73_RS15345	ENOG4108VJ1	Transcriptional regulator (CarD family
HKK73_RS15360	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HKK73_RS15365	ENOG4105E2Z	phosphate ABC transporter (Permease
HKK73_RS15385	ENOG4105BZU	Histidine kinase
HKK73_RS15390	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HKK73_RS15395	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HKK73_RS15405	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HKK73_RS15425	ENOG4105CRK	lysyL-tRNA synthetase
HKK73_RS15435	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HKK73_RS15440	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HKK73_RS15475	ENOG4105EEI	dihydropteroate synthase
HKK73_RS15480	ENOG4105EUJ	GTP cyclohydrolase i
HKK73_RS15485	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HKK73_RS15490	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HKK73_RS15495	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HKK73_RS15505	ENOG4105VGJ	Virulence-associated protein
HKK73_RS15510	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
HKK73_RS15520	ENOG4105F0N	pyrophosphate phospho-hydrolase
HKK73_RS15530	ENOG4108IQK	o-acetylhomoserine
HKK73_RS15535	ENOG4105DWV	Homoserine O-trans-acetylase
HKK73_RS15540	ENOG4105CB2	alcohol dehydrogenase
HKK73_RS15615	ENOG4107S5I	aldo keto reductase
HKK73_RS15625	ENOG4105CCI	Myosin-Cross-Reactive Antigen
HKK73_RS15630	ENOG4105CQB	FAD linked oxidase domain protein
HKK73_RS15665	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
HKK73_RS15710	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
HKK73_RS15760	ENOG4107QUT	magnesium and cobalt transport protein CorA
HKK73_RS15770	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HKK73_RS15780	ENOG4105TT9	Protein of unknown function (DUF2516)
HKK73_RS15800	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HKK73_RS15805	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
HKK73_RS15835	ENOG4105D74	hydrolase
HKK73_RS15860	ENOG4108JQC	penicillin-binding protein 1A
HKK73_RS15865	ENOG4105DIN	metallophosphoesterase
HKK73_RS15885	ENOG4105CR4	methylisocitrate lyase
HKK73_RS15890	ENOG4105DXD	2-methylcitrate dehydratase
HKK73_RS15895	ENOG4105DRR	Transcriptional regulator, GntR family
HKK73_RS15905	ENOG4108KPJ	rna polymerase sigma factor
HKK73_RS15910	ENOG4108RF1	Protein of unknown function DUF2625
HKK73_RS15930	ENOG4105RNG	membrane
HKK73_RS15935	ENOG4105K6V	RNA polymerase
HKK73_RS15940	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HKK73_RS15945	ENOG4105E09	nadh pyrophosphatase
HKK73_RS15955	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
HKK73_RS15965	ENOG410635A	Membrane
HKK73_RS15970	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HKK73_RS15980	ENOG4105CJ1	ABC, transporter
HKK73_RS15990	ENOG4108JJB	ABC transporter
HKK73_RS16015	ENOG4105CFH	Aspartokinase
HKK73_RS16020	ENOG4107V9H	nitrite transporter
HKK73_RS16050	ENOG41082BM	Transcriptional regulator, arsr family
HKK73_RS16065	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HKK73_RS16075	ENOG4108UMI	ABC transporter, permease
HKK73_RS16080	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HKK73_RS16085	ENOG4105D01	(LipO)protein
HKK73_RS16100	ENOG4108X07	Tetr family transcriptional regulator
HKK73_RS16105	ENOG4105CIG	ABC transporter
HKK73_RS16110	ENOG4105DIM	ABC transporter
HKK73_RS16135	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HKK73_RS16140	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HKK73_RS16145	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HKK73_RS16175	ENOG4105C2W	permease
HKK73_RS16220	ENOG4105YIP	Tetr family transcriptional regulator
HKK73_RS16240	ENOG4108IG5	Transcriptional regulator
HKK73_RS16250	ENOG4105C1G	acyl-Coa dehydrogenase
HKK73_RS16255	ENOG4105CHU	acetyl-coa acetyltransferase
HKK73_RS16270	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
HKK73_RS16360	ENOG4108Z6B	deaminase
HKK73_RS16365	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HKK73_RS16370	ENOG4107NHD	transcriptional regulator
HKK73_RS16395	ENOG4105KNI	merR family transcriptional Regulator
HKK73_RS16400	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HKK73_RS16410	ENOG4105CFG	Acts as a chaperone (By similarity)
HKK73_RS16415	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HKK73_RS16420	ENOG4105VEQ	Cold shock protein
HKK73_RS16445	ENOG4108IJ0	Aspartate ammonia-lyase
HKK73_RS16460	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
HKK73_RS16475	ENOG4105ETE	Transcriptional regulator (LacI family
HKK73_RS16495	ENOG4105DKK	Benzoate
HKK73_RS16505	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
HKK73_RS16525	ENOG4105E2R	ROK family
HKK73_RS16550	ENOG4105Y3U	Transglycosylase-associated protein
HKK73_RS16570	ENOG4107QP8	phosphohexose isomerase
HKK73_RS16575	ENOG4107MMM	Anti-sigma-factor antagonist
HKK73_RS16580	ENOG4105FUA	antagonist
HKK73_RS16585	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
HKK73_RS16595	ENOG4105BZU	Histidine kinase
HKK73_RS16600	ENOG4105ETX	regulatoR
HKK73_RS16615	ENOG4105BZU	Histidine kinase
HKK73_RS16620	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS16630	ENOG4108UCS	ABC, transporter
HKK73_RS16640	ENOG4105DP9	ABC transporter
HKK73_RS16645	ENOG4105C19	ABC transporter
HKK73_RS16705	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HKK73_RS16725	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HKK73_RS16730	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HKK73_RS16745	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HKK73_RS16780	ENOG4108HF7	Gcn5-related n-acetyltransferase
HKK73_RS16815	ENOG4105X1Q	TOBE domain protein
HKK73_RS16835	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HKK73_RS16840	ENOG4105C6Z	Gluconate
HKK73_RS16860	ENOG41081K0	peptidylprolyl cis-trans isomerase
HKK73_RS16870	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HKK73_RS16895	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HKK73_RS16910	ENOG4105CMG	Carbohydrate kinase
HKK73_RS16945	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HKK73_RS16955	ENOG4105CEY	Amp-dependent synthetase and ligase
HKK73_RS16980	ENOG4105IIU	Aminopeptidase
HKK73_RS16985	ENOG4105DVT	helicase
HKK73_RS17010	ENOG4105UYK	outer membrane protein a
HKK73_RS17020	ENOG41090KN	UPF0303 protein
HKK73_RS17060	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
HKK73_RS17065	ENOG4105GCF	PGAM
HKK73_RS17070	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HKK73_RS17085	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HKK73_RS17090	ENOG4108IJG	ABC transporter substrate-binding protein
HKK73_RS17100	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HKK73_RS17120	ENOG4105BZU	Histidine kinase
HKK73_RS17130	ENOG4108VCA	G U mismatch-specific DNA glycosylase
HKK73_RS17135	ENOG4105FB2	class II Aldolase
HKK73_RS17145	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
HKK73_RS17150	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HKK73_RS17155	ENOG41069H7	transport system small permease component
HKK73_RS17160	ENOG4105CPQ	Dehydrogenase
HKK73_RS17165	ENOG4107YCY	Transcriptional regulator
HKK73_RS17170	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS17175	ENOG4105ENA	helicase
HKK73_RS17180	ENOG4107QRT	dEAD DEAH box helicase
HKK73_RS17190	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HKK73_RS17220	ENOG4105C0D	helicase
HKK73_RS17345	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HKK73_RS17375	ENOG4105HDK	L-asparaginase
HKK73_RS17390	ENOG4105CI0	Citrate lyase
HKK73_RS17395	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HKK73_RS17400	ENOG4105E6M	Sulphatase-modifying factor protein
HKK73_RS17405	ENOG4108RVA	ribokinase
HKK73_RS17435	ENOG4105ETE	Transcriptional regulator (LacI family
HKK73_RS17460	ENOG4105K5B	UPF0225 protein
HKK73_RS17470	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HKK73_RS17510	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HKK73_RS17515	ENOG4105ETE	Transcriptional regulator (LacI family
HKK73_RS17565	ENOG4105DZG	Dehydrogenase
HKK73_RS17575	ENOG4108IV0	ABC, transporter
HKK73_RS17580	ENOG4105C0Z	ABC transporter
HKK73_RS17590	ENOG4105C32	Amino acid ABC transporter (Permease)
HKK73_RS17595	ENOG4105CP9	extracellular ligand-binding receptor
HKK73_RS17600	ENOG4105VEQ	Cold shock protein
HKK73_RS17625	ENOG4105CDA	abc transporter atp-binding protein
HKK73_RS17630	ENOG4105E5Q	amino acid AbC transporter
HKK73_RS17645	ENOG4105C8J	)-transporter
HKK73_RS17650	ENOG4105QE3	oxidoreductase
HKK73_RS17700	ENOG4108IG5	Transcriptional regulator
HKK73_RS17705	ENOG4105EYH	Exonuclease
HKK73_RS17715	ENOG41082AN	stage II sporulation protein
HKK73_RS17720	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HKK73_RS17735	ENOG4108UZE	carboxy-peptidase
HKK73_RS17780	ENOG41088SP	formiminoglutamate hydrolase
HKK73_RS17785	ENOG4105CI2	imidazolone-5-propionate hydrolase
HKK73_RS17790	ENOG4105CGP	Urocanate hydratase
HKK73_RS17795	ENOG4105C84	Histidine ammonia-lyase
HKK73_RS17800	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HKK73_RS17825	ENOG4105DIK	(ABC) transporter
HKK73_RS17840	ENOG4107TE5	Lipid kinase
HKK73_RS17875	ENOG4105CIR	epoxide hydrolase
HKK73_RS17895	ENOG4105CQ7	ATP-dependent helicase
HKK73_RS17905	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HKK73_RS17935	ENOG4108UVJ	appr-1-p processing domain protein
HKK73_RS17985	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HKK73_RS17990	ENOG4105EJQ	L-serine dehydratase
HKK73_RS17995	ENOG4108UW5	maltose o-acetyltransferase
HKK73_RS18050	ENOG4105VUF	Transcriptional regulator
HKK73_RS18065	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS18070	ENOG4105BZU	Histidine kinase
HKK73_RS18080	ENOG4105CEY	Amp-dependent synthetase and ligase
HKK73_RS18085	ENOG4105C85	amino acid
HKK73_RS18095	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HKK73_RS18100	ENOG4107RWR	Sodium hydrogen exchanger
HKK73_RS18130	ENOG4108UW5	maltose o-acetyltransferase
HKK73_RS18135	ENOG4108RFG	Tetr family transcriptional regulator
HKK73_RS18145	ENOG4105D22	carbon starvation protein
HKK73_RS18180	ENOG4108MES	Periplasmic binding protein
HKK73_RS18185	ENOG4108HRK	Histidine kinase
HKK73_RS18190	ENOG4105DY9	regulatoR
HKK73_RS18205	ENOG4105SYT	Methylenetetrahydrofolate reductase
HKK73_RS18210	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HKK73_RS18230	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HKK73_RS18245	ENOG4107R13	MMPL domain protein
HKK73_RS18255	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HKK73_RS18260	ENOG4106UW1	Major Facilitator superfamily
HKK73_RS18305	ENOG4105CQB	FAD linked oxidase domain protein
HKK73_RS18310	ENOG4106KNT	transcriptional regulator
HKK73_RS18315	ENOG4105RD7	BadF BadG BcrA BcrD
HKK73_RS18320	ENOG4105WH1	Two component transcriptional regulator luxr family
HKK73_RS18325	ENOG4105BZU	Histidine kinase
HKK73_RS18355	ENOG4108V06	Glutathione peroxidase
HKK73_RS18375	ENOG4108RPX	mosc domain containing protein
HKK73_RS18420	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
HKK73_RS18465	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
HKK73_RS18495	ENOG4105KPY	Small multidrug resistance protein
HKK73_RS18510	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HKK73_RS18530	ENOG4105NPE	arsR family transcriptional regulator
HKK73_RS18540	ENOG41083TI	Protein CrcB homolog
HKK73_RS18545	ENOG41085J0	Protein CrcB homolog
HKK73_RS18560	ENOG4105CEU	Arginine dihydrolase
HKK73_RS18565	ENOG4105D5Q	Arginine ornithine antiporter
HKK73_RS18575	ENOG4105DRR	Transcriptional regulator, GntR family
HKK73_RS18585	ENOG4107T40	Inherit from COG: Glycosyltransferase 36
HKK73_RS18590	ENOG4105U5Y	Transcriptional regulator
HKK73_RS18595	ENOG4107T3P	ABC, transporter
HKK73_RS18605	ENOG4105DRS	transport system, permease
HKK73_RS18615	ENOG4105ETE	Transcriptional regulator (LacI family
HKK73_RS18620	ENOG4105E2V	Glycosyltransferase 36
HKK73_RS18625	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HKK73_RS18630	ENOG4105KI2	Urea amidohydrolase subunit beta
HKK73_RS18635	ENOG4105CQM	Urea amidohydrolase subunit alpha
HKK73_RS18645	ENOG4107S16	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HKK73_RS18650	ENOG4105MT3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HKK73_RS18655	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
HKK73_RS18675	ENOG4105C0Z	ABC transporter
HKK73_RS18680	ENOG4108IV0	ABC, transporter
HKK73_RS18685	ENOG4105DRR	Transcriptional regulator, GntR family
HKK73_RS18695	ENOG4105CDU	Replicative dna helicase
HKK73_RS18700	ENOG4105UQX	Mate efflux family protein
HKK73_RS18705	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HKK73_RS18710	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HKK73_RS18720	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
HKK73_RS18725	ENOG4105BZ4	penicillin-binding protein
HKK73_RS18735	ENOG4105CZA	synthase
HKK73_RS18745	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HKK73_RS18750	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKK73_RS18775	ENOG4105C3M	thioredoxin reductase
HKK73_RS18780	ENOG4105K63	Thioredoxin
HKK73_RS18785	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HKK73_RS18790	ENOG4105CPF	Cell wall formation (By similarity)
HKK73_RS18800	ENOG4107QJE	Chromosome Partitioning Protein
HKK73_RS18805	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HKK73_RS18810	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
HKK73_RS18815	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKK73_RS18820	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HKK73_RS18825	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HKK73_RS18830	ENOG41084CH	50S ribosomal protein l34