locus-tag	class	description
BKB87_RS00055	COG1560	Kdo2-lipid A biosynthetic process
BKB87_RS00065	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BKB87_RS00070	COG1271	oxidase subunit
BKB87_RS00075	COG1294	oxidase, subunit
BKB87_RS00080	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BKB87_RS00110	COG0681	Belongs to the peptidase S26 family
BKB87_RS00135	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BKB87_RS00175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BKB87_RS00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BKB87_RS00280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKB87_RS00295	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKB87_RS00315	COG0633	Ferredoxin
BKB87_RS00325	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKB87_RS00330	COG1191	sigma factor activity
BKB87_RS00480	COG4789	Type iii secretion
BKB87_RS00485	COG4792	protein secretion
BKB87_RS00490	COG0012	GTP binding
BKB87_RS00495	COG0196	riboflavin kinase activity
BKB87_RS00515	COG0195	Participates in both transcription termination and antitermination
BKB87_RS00550	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BKB87_RS00560	COG0564	pseudouridine synthase activity
BKB87_RS00585	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKB87_RS00590	COG1164	Oligoendopeptidase f
BKB87_RS00650	COG0439	Biotin carboxylase
BKB87_RS00675	COG0765	amino acid transport
BKB87_RS00680	COG1126	abc transporter atp-binding protein
BKB87_RS00725	COG4166	transmembrane transport
BKB87_RS00735	COG3318	Belongs to the UPF0149 family
BKB87_RS00735	COG3012	SEC-C Motif Domain Protein
BKB87_RS00780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKB87_RS00800	COG1136	(ABC) transporter
BKB87_RS00930	COG4166	transmembrane transport
BKB87_RS00955	COG1116	anion transmembrane transporter activity
BKB87_RS00990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BKB87_RS01000	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BKB87_RS01035	COG2239	Acts as a magnesium transporter
BKB87_RS01055	COG4166	transmembrane transport
BKB87_RS01060	COG0601	transmembrane transport
BKB87_RS01065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKB87_RS01070	COG0444	Belongs to the ABC transporter superfamily
BKB87_RS01075	COG4608	Belongs to the ABC transporter superfamily
BKB87_RS01085	COG0471	metal ion transport
BKB87_RS01090	COG0205	6-phosphofructokinase activity
BKB87_RS01155	COG0531	amino acid
BKB87_RS01160	COG0037	tRNA processing
BKB87_RS01170	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BKB87_RS01180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKB87_RS01240	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BKB87_RS01245	COG0733	neurotransmitter:sodium symporter activity
BKB87_RS01280	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKB87_RS01295	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKB87_RS01315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKB87_RS01320	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKB87_RS01320	COG0022	dehydrogenase e1 component
BKB87_RS01325	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKB87_RS01360	COG1266	CAAX protease self-immunity
BKB87_RS01375	COG4536	flavin adenine dinucleotide binding
BKB87_RS01385	COG1104	cysteine desulfurase activity
BKB87_RS01390	COG0631	protein serine/threonine phosphatase activity
BKB87_RS01405	COG2176	DNA-directed DNA polymerase activity
BKB87_RS01410	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BKB87_RS01420	COG1132	(ABC) transporter
BKB87_RS01440	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKB87_RS01450	COG0768	penicillin binding
BKB87_RS01520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKB87_RS01555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKB87_RS01565	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BKB87_RS01575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKB87_RS01740	COG2166	iron-sulfur cluster assembly
BKB87_RS01810	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BKB87_RS01845	COG0022	dehydrogenase e1 component
BKB87_RS01885	COG0488	(ABC) transporter
BKB87_RS01925	COG1331	Highly conserved protein containing a thioredoxin domain
BKB87_RS02050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKB87_RS02055	COG0321	lipoyl(octanoyl) transferase activity
BKB87_RS02055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BKB87_RS02065	COG1605	Chorismate mutase
BKB87_RS02065	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BKB87_RS02165	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKB87_RS02170	COG1301	dicarboxylic acid transport
BKB87_RS02180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKB87_RS02200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BKB87_RS02210	COG1115	amino acid carrier protein
BKB87_RS02215	COG0617	tRNA 3'-terminal CCA addition
BKB87_RS02310	COG1366	Belongs to the anti-sigma-factor antagonist family
BKB87_RS02325	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BKB87_RS02370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BKB87_RS02400	COG0793	Belongs to the peptidase S41A family
BKB87_RS02410	COG1361	Conserved repeat domain
BKB87_RS02435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BKB87_RS02440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKB87_RS02440	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKB87_RS02470	COG0204	Acyl-transferase
BKB87_RS02470	COG0318	PFAM AMP-dependent synthetase and ligase
BKB87_RS02495	COG1247	-acetyltransferase
BKB87_RS02525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKB87_RS02615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKB87_RS02620	COG0601	transmembrane transport
BKB87_RS02665	COG0742	ribosomal rna small subunit methyltransferase
BKB87_RS02675	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BKB87_RS02685	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BKB87_RS02695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKB87_RS02695	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKB87_RS02700	COG0616	signal peptide processing
BKB87_RS02710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BKB87_RS02725	COG0305	Participates in initiation and elongation during chromosome replication
BKB87_RS02930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BKB87_RS02955	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BKB87_RS03015	COG1686	Belongs to the peptidase S11 family
BKB87_RS03035	COG1114	Component of the transport system for branched-chain amino acids
BKB87_RS03060	COG4669	(LipO)protein
BKB87_RS03085	COG4794	Type iii secretion
BKB87_RS03120	COG1459	type II secretion system
BKB87_RS03225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BKB87_RS03245	COG0084	hydrolase, TatD family'
BKB87_RS03255	COG0811	peptide transport
BKB87_RS03275	COG2885	chlorophyll binding
BKB87_RS03280	COG1388	LysM domain
BKB87_RS03280	COG4641	Protein conserved in bacteria
BKB87_RS03290	COG0450	alkyl hydroperoxide reductase
BKB87_RS03300	COG0459	protein refolding
BKB87_RS03305	COG3876	Protein conserved in bacteria
BKB87_RS03325	COG0210	DNA helicase
BKB87_RS03330	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BKB87_RS03430	COG0142	geranyltranstransferase activity
BKB87_RS03435	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BKB87_RS03505	COG2814	Major facilitator Superfamily
BKB87_RS03515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKB87_RS03520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BKB87_RS03545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BKB87_RS03560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BKB87_RS03600	COG0564	pseudouridine synthase activity
BKB87_RS03675	COG2815	serine threonine protein kinase
BKB87_RS03675	COG0515	serine threonine protein kinase
BKB87_RS03745	COG0768	penicillin binding
BKB87_RS03755	COG0719	Fe-S assembly protein
BKB87_RS03760	COG0396	ATPase activity
BKB87_RS03765	COG0719	Fe-S assembly protein
BKB87_RS03780	COG4608	Belongs to the ABC transporter superfamily
BKB87_RS03785	COG0444	Belongs to the ABC transporter superfamily
BKB87_RS03820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BKB87_RS03885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKB87_RS03890	COG1077	Cell shape determining protein MreB Mrl
BKB87_RS03920	COG4284	Utp--glucose-1-phosphate uridylyltransferase
BKB87_RS03930	COG1157	protein secretion by the type III secretion system
BKB87_RS03960	COG1187	pseudouridine synthase activity
BKB87_RS03970	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BKB87_RS03970	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BKB87_RS03975	COG0772	Belongs to the SEDS family
BKB87_RS04020	COG1115	amino acid carrier protein
BKB87_RS04035	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BKB87_RS04095	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BKB87_RS04100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKB87_RS04110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BKB87_RS04140	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BKB87_RS04165	COG0459	protein refolding
BKB87_RS04175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BKB87_RS04195	COG0772	Belongs to the SEDS family
BKB87_RS04210	COG1837	Belongs to the UPF0109 family
BKB87_RS04220	COG1366	Belongs to the anti-sigma-factor antagonist family
BKB87_RS04230	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BKB87_RS04240	COG0799	negative regulation of ribosome biogenesis
BKB87_RS04245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKB87_RS04270	COG1218	3'(2'),5'-bisphosphate nucleotidase
BKB87_RS04285	COG0156	8-amino-7-oxononanoate synthase activity
BKB87_RS04300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKB87_RS04315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKB87_RS04450	COG1025	Belongs to the peptidase M16 family
BKB87_RS04520	COG0814	amino acid
BKB87_RS04525	COG0814	amino acid
BKB87_RS04535	COG0552	protein localization to endoplasmic reticulum
BKB87_RS04545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BKB87_RS04595	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BKB87_RS04725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKB87_RS04735	COG0659	secondary active sulfate transmembrane transporter activity