locus-tag	class	description
PLUT_RS00005	COG0592	DNA-directed DNA polymerase activity
PLUT_RS00010	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PLUT_RS00020	COG0426	domain, Protein
PLUT_RS00030	COG0445	tRNA wobble uridine modification
PLUT_RS00035	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PLUT_RS00040	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PLUT_RS00045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PLUT_RS00050	COG0187	DNA topoisomerase II activity
PLUT_RS00055	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PLUT_RS00060	COG1530	ribonuclease E activity
PLUT_RS00065	COG2171	N-acyltransferase activity
PLUT_RS00070	COG0793	Belongs to the peptidase S41A family
PLUT_RS00080	COG0644	oxidoreductase
PLUT_RS00085	COG0423	glycine-tRNA ligase activity
PLUT_RS00095	COG1619	proteins homologs of microcin C7 resistance protein MccF
PLUT_RS00105	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PLUT_RS00115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PLUT_RS00120	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
PLUT_RS00130	COG3360	Dodecin
PLUT_RS00140	COG0243	molybdopterin cofactor binding
PLUT_RS00155	COG2210	Belongs to the sulfur carrier protein TusA family
PLUT_RS00165	COG0425	Belongs to the sulfur carrier protein TusA family
PLUT_RS00170	COG1797	cobyrinic acid a,c-diamide synthase activity
PLUT_RS00175	COG2920	part of a sulfur-relay system
PLUT_RS00180	COG2221	Nitrite and sulphite reductase 4Fe-4S
PLUT_RS00185	COG2221	Nitrite and sulphite reductase 4Fe-4S
PLUT_RS00200	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PLUT_RS00205	COG2923	Belongs to the DsrF TusC family
PLUT_RS00235	COG0437	4 iron, 4 sulfur cluster binding
PLUT_RS00245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PLUT_RS00245	COG1648	precorrin-2 dehydrogenase activity
PLUT_RS00250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PLUT_RS00250	COG1648	precorrin-2 dehydrogenase activity
PLUT_RS00270	COG2814	Major facilitator Superfamily
PLUT_RS00310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PLUT_RS00320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PLUT_RS00330	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
PLUT_RS00355	COG0446	pyridine nucleotide-disulphide oxidoreductase
PLUT_RS00360	COG0778	Nitroreductase
PLUT_RS00370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PLUT_RS00380	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PLUT_RS00390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PLUT_RS00395	COG0284	orotidine-5'-phosphate decarboxylase activity
PLUT_RS00400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PLUT_RS00435	COG1090	epimerase
PLUT_RS00440	COG0724	RNA recognition motif
PLUT_RS00450	COG0347	Belongs to the P(II) protein family
PLUT_RS00475	COG0802	atpase or kinase
PLUT_RS00480	COG1214	PFAM Peptidase M22, glycoprotease
PLUT_RS00485	COG0799	negative regulation of ribosome biogenesis
PLUT_RS00500	COG0504	CTP synthase activity
PLUT_RS00505	COG1196	nuclear chromosome segregation
PLUT_RS00505	COG3264	Mechanosensitive ion channel
PLUT_RS00545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PLUT_RS00580	COG2154	pterin-4-alpha-carbinolamine dehydratase
PLUT_RS00600	COG0824	Thioesterase
PLUT_RS00615	COG0708	Exodeoxyribonuclease III
PLUT_RS00620	COG0360	Binds together with S18 to 16S ribosomal RNA
PLUT_RS00625	COG0629	single-stranded DNA binding
PLUT_RS00630	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PLUT_RS00635	COG0359	binds to the 23S rRNA
PLUT_RS00645	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PLUT_RS00650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PLUT_RS00655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PLUT_RS00660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PLUT_RS00665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PLUT_RS00670	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
PLUT_RS00675	COG1472	Belongs to the glycosyl hydrolase 3 family
PLUT_RS00685	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PLUT_RS00690	COG0571	ribonuclease III activity
PLUT_RS00695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PLUT_RS00700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PLUT_RS00705	COG1028	Short-chain dehydrogenase reductase Sdr
PLUT_RS00710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PLUT_RS00715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PLUT_RS00720	COG0416	fatty acid biosynthetic process
PLUT_RS00725	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PLUT_RS00745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PLUT_RS00755	COG1121	(ABC) transporter
PLUT_RS00760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PLUT_RS00765	COG0589	response to stress
PLUT_RS00770	COG0315	cyclic pyranopterin monophosphate synthase activity
PLUT_RS00770	COG0746	molybdenum cofactor guanylyltransferase activity
PLUT_RS00785	COG0584	glycerophosphoryl diester phosphodiesterase
PLUT_RS00790	COG0521	Mo-molybdopterin cofactor biosynthetic process
PLUT_RS00790	COG0315	cyclic pyranopterin monophosphate synthase activity
PLUT_RS00795	COG0303	'Molybdopterin
PLUT_RS00800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PLUT_RS00810	COG3245	cytochrome
PLUT_RS00820	COG1032	radical SAM domain protein
PLUT_RS00830	COG0505	Belongs to the CarA family
PLUT_RS00835	COG1862	Preprotein translocase
PLUT_RS00840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PLUT_RS00855	COG0542	response to heat
PLUT_RS00865	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PLUT_RS00870	COG1722	exodeoxyribonuclease VII activity
PLUT_RS00875	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PLUT_RS00880	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PLUT_RS00885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PLUT_RS00890	COG0438	transferase activity, transferring glycosyl groups
PLUT_RS00905	COG0438	transferase activity, transferring glycosyl groups
PLUT_RS00925	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PLUT_RS00930	COG0049	tRNA binding
PLUT_RS00935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PLUT_RS00940	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PLUT_RS00945	COG0051	transcription antitermination factor activity, RNA binding
PLUT_RS00950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PLUT_RS00955	COG0088	Forms part of the polypeptide exit tunnel
PLUT_RS00960	COG0089	rRNA binding
PLUT_RS00970	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PLUT_RS00975	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PLUT_RS00980	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PLUT_RS00985	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PLUT_RS00990	COG0255	Belongs to the universal ribosomal protein uL29 family
PLUT_RS00995	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PLUT_RS01000	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PLUT_RS01010	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PLUT_RS01015	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PLUT_RS01020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PLUT_RS01025	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PLUT_RS01030	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PLUT_RS01035	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PLUT_RS01040	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PLUT_RS01045	COG1841	ribosomal large subunit assembly
PLUT_RS01050	COG0200	Binds to the 23S rRNA
PLUT_RS01065	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PLUT_RS01070	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PLUT_RS01075	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PLUT_RS01080	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PLUT_RS01085	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PLUT_RS01090	COG0202	RNA polymerase activity
PLUT_RS01095	COG0203	ribosomal protein L17
PLUT_RS01100	COG0357	Ribosomal RNA small subunit methyltransferase G
PLUT_RS01105	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PLUT_RS01105	COG0662	Cupin 2, conserved barrel domain protein
PLUT_RS01110	COG0215	cysteine-tRNA ligase activity
PLUT_RS01115	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PLUT_RS01120	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PLUT_RS01130	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
PLUT_RS01135	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
PLUT_RS01140	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
PLUT_RS01155	COG0297	glycogen (starch) synthase activity
PLUT_RS01160	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PLUT_RS01165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PLUT_RS01175	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PLUT_RS01180	COG1940	carbohydrate kinase activity
PLUT_RS01185	COG1040	competence protein
PLUT_RS01200	COG0105	UTP biosynthetic process
PLUT_RS01205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PLUT_RS01210	COG1253	flavin adenine dinucleotide binding
PLUT_RS01230	COG1104	cysteine desulfurase activity
PLUT_RS01240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PLUT_RS01245	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PLUT_RS01250	COG0170	dolichyl monophosphate biosynthetic process
PLUT_RS01260	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PLUT_RS01265	COG0463	Glycosyl transferase, family 2
PLUT_RS01275	COG1278	Cold shock
PLUT_RS01305	COG0071	Belongs to the small heat shock protein (HSP20) family
PLUT_RS01315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PLUT_RS01320	COG1429	ligase activity, forming nitrogen-metal bonds
PLUT_RS01330	COG1429	ligase activity, forming nitrogen-metal bonds
PLUT_RS01335	COG4771	TonB-dependent receptor
PLUT_RS01360	COG0629	single-stranded DNA binding
PLUT_RS01365	COG0543	2 iron, 2 sulfur cluster binding
PLUT_RS01410	COG0736	holo-[acyl-carrier-protein] synthase activity
PLUT_RS01415	COG0544	peptidyl-prolyl cis-trans isomerase activity
PLUT_RS01420	COG0612	Peptidase, M16
PLUT_RS01430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PLUT_RS01435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PLUT_RS01440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PLUT_RS01455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PLUT_RS01470	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PLUT_RS01475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PLUT_RS01480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PLUT_RS01490	COG1078	dGTPase activity
PLUT_RS01500	COG2314	TM2 domain
PLUT_RS01505	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PLUT_RS01520	COG1047	Peptidyl-prolyl cis-trans
PLUT_RS01525	COG0826	peptidase U32
PLUT_RS01535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PLUT_RS01545	COG1067	ATP-dependent peptidase activity
PLUT_RS01550	COG0861	Integral membrane protein TerC family
PLUT_RS01555	COG1012	belongs to the aldehyde dehydrogenase family
PLUT_RS01560	COG1752	Esterase of the alpha-beta hydrolase superfamily
PLUT_RS01585	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PLUT_RS01590	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PLUT_RS01595	COG0363	glucosamine-6-phosphate deaminase activity
PLUT_RS01600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PLUT_RS01620	COG2989	Protein conserved in bacteria
PLUT_RS01645	COG0482	sulfurtransferase activity
PLUT_RS01655	COG2239	Acts as a magnesium transporter
PLUT_RS01660	COG2094	Belongs to the DNA glycosylase MPG family
PLUT_RS01665	COG1192	Involved in chromosome partitioning
PLUT_RS01670	COG1475	DNA binding
PLUT_RS01675	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PLUT_RS01685	COG0318	PFAM AMP-dependent synthetase and ligase
PLUT_RS01690	COG4948	Mandelate Racemase Muconate Lactonizing
PLUT_RS01710	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PLUT_RS01715	COG1169	isochorismate synthase
PLUT_RS01740	COG0372	Belongs to the citrate synthase family
PLUT_RS01745	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PLUT_RS01750	COG1872	DUF167
PLUT_RS01755	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PLUT_RS01760	COG1570	exodeoxyribonuclease VII activity
PLUT_RS01770	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
PLUT_RS01775	COG4191	Histidine kinase
PLUT_RS01780	COG2204	response regulator
PLUT_RS01800	COG0233	cytoplasmic translational termination
PLUT_RS01805	COG0254	rRNA binding
PLUT_RS01810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PLUT_RS01815	COG1162	GTPase activity
PLUT_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
PLUT_RS01830	COG1597	lipid kinase activity
PLUT_RS01845	COG1611	Belongs to the LOG family
PLUT_RS01860	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PLUT_RS01865	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PLUT_RS01870	COG1752	Esterase of the alpha-beta hydrolase superfamily
PLUT_RS01875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PLUT_RS01895	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
PLUT_RS01945	COG0745	RESPONSE REGULATOR receiver
PLUT_RS01955	COG2205	protein histidine kinase activity
PLUT_RS01975	COG2274	protein secretion by the type I secretion system
PLUT_RS01985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLUT_RS01990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PLUT_RS02000	COG0740	serine-type endopeptidase activity
PLUT_RS02005	COG0525	valine-tRNA ligase activity
PLUT_RS02010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PLUT_RS02025	COG0612	Peptidase, M16
PLUT_RS02035	COG0556	nucleotide-excision repair
PLUT_RS02040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PLUT_RS02045	COG1704	LemA family
PLUT_RS02060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PLUT_RS02065	COG1674	ftsk spoiiie
PLUT_RS02070	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PLUT_RS02075	COG0489	protein tyrosine kinase activity
PLUT_RS02080	COG1160	GTP binding
PLUT_RS02085	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PLUT_RS02090	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PLUT_RS02095	COG0052	Belongs to the universal ribosomal protein uS2 family
PLUT_RS02100	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PLUT_RS02105	COG0528	UMP kinase activity
PLUT_RS02110	COG2137	regulation of response to DNA damage stimulus
PLUT_RS02115	COG1032	radical SAM domain protein
PLUT_RS02130	COG1028	Short-chain dehydrogenase reductase Sdr
PLUT_RS02130	COG3347	Dehydrogenase
PLUT_RS02140	COG1850	ribulose-bisphosphate carboxylase activity
PLUT_RS02160	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PLUT_RS02170	COG1091	dTDP-4-dehydrorhamnose reductase activity
PLUT_RS02180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PLUT_RS02195	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PLUT_RS02205	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PLUT_RS02220	COG2177	Part of the ABC transporter FtsEX involved in
PLUT_RS02225	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PLUT_RS02230	COG0463	Glycosyl transferase, family 2
PLUT_RS02235	COG0602	queuosine metabolic process
PLUT_RS02240	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PLUT_RS02245	COG0138	bifunctional purine biosynthesis protein purh
PLUT_RS02260	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
PLUT_RS02280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PLUT_RS02290	COG1127	ABC transporter
PLUT_RS02295	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PLUT_RS02305	COG1968	undecaprenyl-diphosphatase activity
PLUT_RS02310	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PLUT_RS02315	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PLUT_RS02320	COG1193	negative regulation of DNA recombination
PLUT_RS02325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PLUT_RS02335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PLUT_RS02365	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PLUT_RS02375	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PLUT_RS02385	COG1692	metallophosphoesterase
PLUT_RS02390	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PLUT_RS02405	COG0463	Glycosyl transferase, family 2
PLUT_RS02410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PLUT_RS02415	COG0671	phosphoesterase, PA-phosphatase related
PLUT_RS02420	COG0788	formyltetrahydrofolate deformylase activity
PLUT_RS02425	COG1230	cation diffusion facilitator family transporter
PLUT_RS02430	COG3040	lipid binding
PLUT_RS02445	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PLUT_RS02450	COG4988	ABC transporter
PLUT_RS02455	COG1294	oxidase, subunit
PLUT_RS02460	COG1271	oxidase subunit
PLUT_RS02465	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PLUT_RS02470	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PLUT_RS02490	COG0084	hydrolase, TatD family'
PLUT_RS02495	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PLUT_RS02500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PLUT_RS02510	COG0322	excinuclease ABC activity
PLUT_RS02515	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PLUT_RS02545	COG0540	Belongs to the ATCase OTCase family
PLUT_RS02550	COG0488	(ABC) transporter
PLUT_RS02565	COG1136	(ABC) transporter
PLUT_RS02565	COG0577	efflux transmembrane transporter activity
PLUT_RS02570	COG0045	succinate-CoA ligase (ADP-forming) activity
PLUT_RS02575	COG0590	tRNA wobble adenosine to inosine editing
PLUT_RS02590	COG0588	phosphoglycerate mutase activity
PLUT_RS02595	COG0070	glutamate synthase
PLUT_RS02595	COG0067	glutamate synthase
PLUT_RS02595	COG0069	glutamate synthase activity
PLUT_RS02600	COG0493	'glutamate synthase
PLUT_RS02610	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PLUT_RS02680	COG4942	peptidase
PLUT_RS02690	COG3588	fructose-bisphosphate aldolase
PLUT_RS02695	COG4232	protein-disulfide reductase activity
PLUT_RS02700	COG0557	exoribonuclease II activity
PLUT_RS02710	COG0519	Catalyzes the synthesis of GMP from XMP
PLUT_RS02710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PLUT_RS02720	COG2195	Cleaves the N-terminal amino acid of tripeptides
PLUT_RS02735	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PLUT_RS02770	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PLUT_RS02780	COG0133	tryptophan synthase activity
PLUT_RS02785	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PLUT_RS02800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PLUT_RS02810	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PLUT_RS02815	COG0459	protein refolding
PLUT_RS02820	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PLUT_RS02830	COG0159	tryptophan synthase activity
PLUT_RS02840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PLUT_RS02855	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PLUT_RS02860	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
PLUT_RS02865	COG0438	transferase activity, transferring glycosyl groups
PLUT_RS02870	COG1077	Cell shape determining protein MreB Mrl
PLUT_RS02875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PLUT_RS02880	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PLUT_RS02885	COG1049	propionate catabolic process, 2-methylcitrate cycle
PLUT_RS02925	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PLUT_RS02930	COG0739	heme binding
PLUT_RS02940	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PLUT_RS02945	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PLUT_RS02950	COG0586	Pfam SNARE associated Golgi protein
PLUT_RS02955	COG1945	arginine decarboxylase activity
PLUT_RS02960	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PLUT_RS02965	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PLUT_RS02970	COG0277	FAD linked oxidase domain protein
PLUT_RS02975	COG0768	penicillin binding
PLUT_RS02985	COG1792	Involved in formation and maintenance of cell shape
PLUT_RS02990	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PLUT_RS02995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PLUT_RS03010	COG2884	Cell division ATP-binding protein ftsE
PLUT_RS03015	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PLUT_RS03025	COG0450	alkyl hydroperoxide reductase
PLUT_RS03030	COG2193	ferroxidase activity
PLUT_RS03035	COG1592	Rubrerythrin
PLUT_RS03040	COG0735	belongs to the Fur family
PLUT_RS03050	COG1519	Transferase
PLUT_RS03060	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PLUT_RS03075	COG4974	Belongs to the 'phage' integrase family
PLUT_RS03080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PLUT_RS03080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PLUT_RS03085	COG2873	o-acetylhomoserine
PLUT_RS03090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PLUT_RS03095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PLUT_RS03105	COG4221	oxidoreductase activity
PLUT_RS03110	COG1278	Cold shock
PLUT_RS03115	COG2003	Belongs to the UPF0758 family
PLUT_RS03120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PLUT_RS03125	COG0066	3-isopropylmalate dehydratase activity
PLUT_RS03130	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PLUT_RS03135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PLUT_RS03140	COG0473	3-isopropylmalate dehydrogenase activity
PLUT_RS03145	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PLUT_RS03150	COG0440	acetolactate synthase activity
PLUT_RS03160	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
PLUT_RS03180	COG0028	Belongs to the TPP enzyme family
PLUT_RS03185	COG0129	dihydroxy-acid dehydratase activity
PLUT_RS03195	COG0811	peptide transport
PLUT_RS03210	COG0823	Involved in the tonB-independent uptake of proteins
PLUT_RS03215	COG2885	chlorophyll binding
PLUT_RS03220	COG2885	chlorophyll binding
PLUT_RS03245	COG0443	Heat shock 70 kDa protein
PLUT_RS03250	COG0071	Belongs to the small heat shock protein (HSP20) family
PLUT_RS03265	COG1595	DNA-templated transcription, initiation
PLUT_RS03275	COG0686	Belongs to the AlaDH PNT family
PLUT_RS03280	COG0633	Ferredoxin
PLUT_RS03285	COG0633	Ferredoxin
PLUT_RS03290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PLUT_RS03295	COG0444	Belongs to the ABC transporter superfamily
PLUT_RS03300	COG0745	RESPONSE REGULATOR receiver
PLUT_RS03305	COG5002	protein histidine kinase activity
PLUT_RS03310	COG0668	transmembrane transport
PLUT_RS03320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PLUT_RS03325	COG1678	Uncharacterized ACR, COG1678
PLUT_RS03390	COG3344	reverse transcriptase
PLUT_RS03435	COG1450	Type ii and iii secretion system protein
PLUT_RS03460	COG0686	Belongs to the AlaDH PNT family
PLUT_RS03480	COG0659	secondary active sulfate transmembrane transporter activity
PLUT_RS03485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PLUT_RS03485	COG0475	glutathione-regulated potassium exporter activity
PLUT_RS03495	COG0135	phosphoribosylanthranilate isomerase activity
PLUT_RS03505	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PLUT_RS03510	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PLUT_RS03620	COG0003	Pfam Anion-transporting ATPase
PLUT_RS03625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PLUT_RS03720	COG0072	phenylalanine-tRNA ligase activity
PLUT_RS03720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PLUT_RS03735	COG1418	mRNA catabolic process
PLUT_RS03740	COG0131	Imidazoleglycerol-phosphate dehydratase
PLUT_RS03755	COG0131	Imidazoleglycerol-phosphate dehydratase
PLUT_RS03795	COG1293	RNA-binding protein homologous to eukaryotic snRNP
PLUT_RS03805	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PLUT_RS03805	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PLUT_RS03815	COG1119	ATPase activity
PLUT_RS03820	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PLUT_RS03825	COG0307	riboflavin synthase, alpha
PLUT_RS03830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PLUT_RS03905	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PLUT_RS03910	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PLUT_RS03915	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PLUT_RS03920	COG0649	NAD binding
PLUT_RS03925	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PLUT_RS03940	COG0713	ATP synthesis coupled electron transport
PLUT_RS03945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PLUT_RS03955	COG1007	ATP synthesis coupled electron transport
PLUT_RS03960	COG0302	gtp cyclohydrolase
PLUT_RS03970	COG3118	belongs to the thioredoxin family
PLUT_RS04005	COG3206	protein involved in exopolysaccharide biosynthesis
PLUT_RS04005	COG0489	protein tyrosine kinase activity
PLUT_RS04010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PLUT_RS04040	COG1216	Glycosyl transferase, family 2
PLUT_RS04045	COG2226	methyltransferase
PLUT_RS04045	COG2867	negative regulation of translational initiation
PLUT_RS04090	COG0488	(ABC) transporter
PLUT_RS04095	COG1505	serine-type exopeptidase activity
PLUT_RS04105	COG0564	pseudouridine synthase activity
PLUT_RS04110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PLUT_RS04115	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
PLUT_RS04120	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
PLUT_RS04120	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
PLUT_RS04125	COG1429	ligase activity, forming nitrogen-metal bonds
PLUT_RS04130	COG0516	GMP reductase activity
PLUT_RS04160	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
PLUT_RS04200	COG1450	Type ii and iii secretion system protein
PLUT_RS04220	COG0531	amino acid
PLUT_RS04250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PLUT_RS04260	COG1858	cytochrome C peroxidase
PLUT_RS04305	COG1061	Type III restriction enzyme res subunit
PLUT_RS04360	COG3077	Addiction module antitoxin, RelB DinJ family
PLUT_RS04470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PLUT_RS04485	COG2208	phosphoserine phosphatase activity
PLUT_RS04485	COG2770	Histidine kinase
PLUT_RS04495	COG0765	amino acid transport
PLUT_RS04500	COG0765	amino acid transport
PLUT_RS04510	COG1366	Belongs to the anti-sigma-factor antagonist family
PLUT_RS04555	COG0535	radical SAM domain protein
PLUT_RS04570	COG2274	protein secretion by the type I secretion system
PLUT_RS04575	COG2274	protein secretion by the type I secretion system
PLUT_RS04605	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PLUT_RS04655	COG0596	Alpha beta hydrolase
PLUT_RS04665	COG0745	RESPONSE REGULATOR receiver
PLUT_RS04675	COG0633	Ferredoxin
PLUT_RS04680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PLUT_RS04695	COG0281	malic enzyme
PLUT_RS04700	COG0791	NLP P60 protein
PLUT_RS04720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PLUT_RS04725	COG4279	zinc finger
PLUT_RS04740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PLUT_RS04740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PLUT_RS04745	COG1342	Belongs to the UPF0251 family
PLUT_RS04755	COG0428	transporter
PLUT_RS04765	COG1216	Glycosyl transferase, family 2
PLUT_RS04765	COG0463	Glycosyl transferase, family 2
PLUT_RS04770	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PLUT_RS04795	COG1686	Belongs to the peptidase S11 family
PLUT_RS04810	COG0038	chloride channel
PLUT_RS04820	COG4603	Belongs to the binding-protein-dependent transport system permease family
PLUT_RS04825	COG3845	ABC transporter
PLUT_RS04835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PLUT_RS04840	COG1950	PFAM Membrane protein of
PLUT_RS04845	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PLUT_RS04850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PLUT_RS04865	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PLUT_RS04870	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PLUT_RS04875	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PLUT_RS04925	COG1032	radical SAM domain protein
PLUT_RS04930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PLUT_RS04935	COG5002	protein histidine kinase activity
PLUT_RS04940	COG0745	RESPONSE REGULATOR receiver
PLUT_RS04945	COG0589	response to stress
PLUT_RS04950	COG0659	secondary active sulfate transmembrane transporter activity
PLUT_RS04955	COG1979	alcohol dehydrogenase
PLUT_RS04960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PLUT_RS04965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PLUT_RS04970	COG0563	adenylate kinase activity
PLUT_RS04980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PLUT_RS04990	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
PLUT_RS04995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PLUT_RS05010	COG0351	phosphomethylpyrimidine kinase
PLUT_RS05010	COG0352	thiamine-phosphate diphosphorylase activity
PLUT_RS05015	COG0352	thiamine-phosphate diphosphorylase activity
PLUT_RS05020	COG0352	thiamine-phosphate diphosphorylase activity
PLUT_RS05045	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PLUT_RS05045	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PLUT_RS05050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PLUT_RS05055	COG0228	four-way junction DNA binding
PLUT_RS05060	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PLUT_RS05065	COG0336	Belongs to the RNA methyltransferase TrmD family
PLUT_RS05070	COG0335	large ribosomal subunit rRNA binding
PLUT_RS05075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PLUT_RS05080	COG1194	a g-specific adenine glycosylase
PLUT_RS05085	COG1022	Amp-dependent synthetase and ligase
PLUT_RS05100	COG1083	cytidylyl-transferase
PLUT_RS05110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PLUT_RS05135	COG1215	transferase activity, transferring glycosyl groups
PLUT_RS05155	COG1322	Protein conserved in bacteria
PLUT_RS05160	COG0513	Belongs to the DEAD box helicase family
PLUT_RS05200	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PLUT_RS05205	COG1074	ATP-dependent DNA helicase activity
PLUT_RS05210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PLUT_RS05225	COG1803	Methylglyoxal synthase
PLUT_RS05240	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PLUT_RS05285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PLUT_RS05300	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PLUT_RS05305	COG0698	ribose 5-phosphate isomerase
PLUT_RS05315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PLUT_RS05320	COG1473	amidohydrolase
PLUT_RS05325	COG0191	fructose-bisphosphate aldolase activity
PLUT_RS05330	COG0793	Belongs to the peptidase S41A family
PLUT_RS05335	COG0724	RNA recognition motif
PLUT_RS05340	COG2205	protein histidine kinase activity
PLUT_RS05380	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PLUT_RS05390	COG2208	phosphoserine phosphatase activity
PLUT_RS05390	COG2770	Histidine kinase
PLUT_RS05400	COG0765	amino acid transport
PLUT_RS05405	COG0765	amino acid transport
PLUT_RS05415	COG1366	Belongs to the anti-sigma-factor antagonist family
PLUT_RS05430	COG3527	Alpha-acetolactate decarboxylase
PLUT_RS05445	COG0165	Argininosuccinate lyase
PLUT_RS05450	COG0137	argininosuccinate synthase activity
PLUT_RS05455	COG1438	arginine binding
PLUT_RS05460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PLUT_RS05465	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PLUT_RS05470	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PLUT_RS05475	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PLUT_RS05485	COG5001	Diguanylate cyclase
PLUT_RS05485	COG3300	MHYT domain
PLUT_RS05490	COG4591	ABC-type transport system involved in lipoprotein release permease component
PLUT_RS05500	COG0523	cobalamin synthesis protein
PLUT_RS05510	COG2119	membrane
PLUT_RS05520	COG0390	transport system, permease component
PLUT_RS05525	COG0501	Belongs to the peptidase M48B family
PLUT_RS05530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PLUT_RS05535	COG0045	succinate-CoA ligase (ADP-forming) activity
PLUT_RS05540	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PLUT_RS05545	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PLUT_RS05565	COG0356	it plays a direct role in the translocation of protons across the membrane
PLUT_RS05575	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PLUT_RS05580	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PLUT_RS05585	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PLUT_RS05595	COG1013	pyruvate-flavodoxin oxidoreductase activity
PLUT_RS05625	COG1129	ABC transporter
PLUT_RS05625	COG0842	Transport permease protein
PLUT_RS05630	COG0842	Transport permease protein
PLUT_RS05635	COG1131	(ABC) transporter
PLUT_RS05640	COG1131	(ABC) transporter
PLUT_RS05645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLUT_RS05655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PLUT_RS05675	COG0653	protein targeting
PLUT_RS05680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PLUT_RS05685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PLUT_RS05685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PLUT_RS05725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PLUT_RS05730	COG5002	protein histidine kinase activity
PLUT_RS05735	COG0745	RESPONSE REGULATOR receiver
PLUT_RS05745	COG0745	RESPONSE REGULATOR receiver
PLUT_RS05770	COG0436	Aminotransferase
PLUT_RS05775	COG1970	mechanosensitive ion channel activity
PLUT_RS05780	COG2048	Heterodisulfide reductase, subunit B
PLUT_RS05810	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PLUT_RS05850	COG2081	HI0933 family
PLUT_RS05865	COG1136	(ABC) transporter
PLUT_RS05880	COG1342	Belongs to the UPF0251 family
PLUT_RS05885	COG1275	C4-dicarboxylate transporter malic acid transport protein
PLUT_RS05895	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PLUT_RS05900	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PLUT_RS05915	COG1120	ATPase activity
PLUT_RS05920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLUT_RS05930	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PLUT_RS05935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PLUT_RS05940	COG1492	cobalamin metabolic process
PLUT_RS05945	COG0778	Nitroreductase
PLUT_RS05960	COG1063	alcohol dehydrogenase
PLUT_RS05970	COG1283	sodium-dependent phosphate transmembrane transporter activity
PLUT_RS05980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PLUT_RS05990	COG0673	inositol 2-dehydrogenase activity
PLUT_RS05995	COG0617	tRNA 3'-terminal CCA addition
PLUT_RS06000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PLUT_RS06010	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
PLUT_RS06010	COG2878	Part of a membrane complex involved in electron transport
PLUT_RS06015	COG4656	Part of a membrane complex involved in electron transport
PLUT_RS06020	COG4658	electron transport chain
PLUT_RS06030	COG4660	Part of a membrane complex involved in electron transport
PLUT_RS06035	COG4657	Part of a membrane complex involved in electron transport
PLUT_RS06040	COG1477	protein flavinylation
PLUT_RS06050	COG0166	Belongs to the GPI family
PLUT_RS06060	COG0004	ammonium transporteR
PLUT_RS06065	COG0347	Belongs to the P(II) protein family
PLUT_RS06080	COG0456	acetyltransferase
PLUT_RS06090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PLUT_RS06120	COG0741	lytic transglycosylase activity
PLUT_RS06125	COG0101	tRNA pseudouridine synthase activity
PLUT_RS06140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PLUT_RS06145	COG0424	maF-like protein
PLUT_RS06150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PLUT_RS06170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PLUT_RS06175	COG3876	Protein conserved in bacteria
PLUT_RS06185	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PLUT_RS06185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PLUT_RS06190	COG1774	PSP1 C-terminal conserved region
PLUT_RS06200	COG0436	Aminotransferase
PLUT_RS06205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PLUT_RS06210	COG0742	ribosomal rna small subunit methyltransferase
PLUT_RS06215	COG3959	Transketolase, thiamine diphosphate binding domain
PLUT_RS06225	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PLUT_RS06255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PLUT_RS06265	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
PLUT_RS06270	COG0193	aminoacyl-tRNA hydrolase activity
PLUT_RS06275	COG0596	Alpha beta hydrolase
PLUT_RS06280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PLUT_RS06285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PLUT_RS06300	COG1702	phosphate starvation-inducible protein PhoH
PLUT_RS06330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PLUT_RS06335	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PLUT_RS06340	COG2815	serine threonine protein kinase
PLUT_RS06340	COG0515	serine threonine protein kinase
PLUT_RS06345	COG0142	geranyltranstransferase activity
PLUT_RS06350	COG0805	protein transport
PLUT_RS06360	COG0237	dephospho-CoA kinase activity
PLUT_RS06370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PLUT_RS06390	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
PLUT_RS06395	COG3118	belongs to the thioredoxin family
PLUT_RS06400	COG2217	Heavy metal translocating P-type atpase
PLUT_RS06420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PLUT_RS06425	COG0277	FAD linked oxidase domain protein
PLUT_RS06430	COG1215	transferase activity, transferring glycosyl groups
PLUT_RS06450	COG0704	Plays a role in the regulation of phosphate uptake
PLUT_RS06455	COG0704	Plays a role in the regulation of phosphate uptake
PLUT_RS06460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PLUT_RS06465	COG0581	inorganic phosphate transmembrane transporter activity
PLUT_RS06470	COG0573	inorganic phosphate transmembrane transporter activity
PLUT_RS06480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PLUT_RS06525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PLUT_RS06535	COG2204	response regulator
PLUT_RS06545	COG0492	ferredoxin-NADP+ reductase activity
PLUT_RS06550	COG3118	belongs to the thioredoxin family
PLUT_RS06560	COG0438	transferase activity, transferring glycosyl groups
PLUT_RS06565	COG1554	hydrolase, family 65, central catalytic
PLUT_RS06595	COG0589	response to stress
PLUT_RS06610	COG0326	Molecular chaperone. Has ATPase activity
PLUT_RS06615	COG2089	acid synthase
PLUT_RS06620	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PLUT_RS06625	COG2326	polyphosphate kinase activity
PLUT_RS06665	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
PLUT_RS06665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PLUT_RS06670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PLUT_RS06675	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PLUT_RS06680	COG3958	Transketolase
PLUT_RS06685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PLUT_RS06695	COG0346	lactoylglutathione lyase activity
PLUT_RS06700	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PLUT_RS06710	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PLUT_RS06710	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PLUT_RS06720	COG0589	response to stress
PLUT_RS06750	COG1518	maintenance of DNA repeat elements
PLUT_RS06755	COG0330	HflC and HflK could
PLUT_RS06760	COG1030	water channel activity
PLUT_RS06765	COG2738	Putative neutral zinc metallopeptidase
PLUT_RS06770	COG0531	amino acid
PLUT_RS06775	COG4221	oxidoreductase activity
PLUT_RS06780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PLUT_RS06795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PLUT_RS06800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PLUT_RS06825	COG2050	protein possibly involved in aromatic compounds catabolism
PLUT_RS06830	COG1032	radical SAM domain protein
PLUT_RS06840	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PLUT_RS06855	COG1295	ribonuclease BN
PLUT_RS06860	COG2270	Major facilitator Superfamily
PLUT_RS06865	COG0047	phosphoribosylformylglycinamidine synthase activity
PLUT_RS06870	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PLUT_RS06880	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PLUT_RS06885	COG0095	Lipoate-protein ligase
PLUT_RS06895	COG1832	CoA-binding protein
PLUT_RS06900	COG1181	Belongs to the D-alanine--D-alanine ligase family
PLUT_RS06920	COG1136	(ABC) transporter
PLUT_RS06930	COG0577	efflux transmembrane transporter activity
PLUT_RS06930	COG1136	(ABC) transporter
PLUT_RS06935	COG3047	cAMP biosynthetic process
PLUT_RS06935	COG2885	chlorophyll binding
PLUT_RS06945	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PLUT_RS06950	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PLUT_RS06955	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PLUT_RS06960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PLUT_RS06965	COG0494	nUDIX hydrolase
PLUT_RS06975	COG0658	competence protein
PLUT_RS06975	COG2333	competence protein COMEC
PLUT_RS06980	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PLUT_RS06990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PLUT_RS07020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PLUT_RS07025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PLUT_RS07035	COG1562	ergosterol biosynthetic process
PLUT_RS07040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PLUT_RS07055	COG2208	phosphoserine phosphatase activity
PLUT_RS07060	COG2204	response regulator
PLUT_RS07070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PLUT_RS07075	COG1366	Belongs to the anti-sigma-factor antagonist family
PLUT_RS07085	COG1366	Belongs to the anti-sigma-factor antagonist family
PLUT_RS07090	COG2172	sigma factor antagonist activity
PLUT_RS07130	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PLUT_RS07140	COG0438	transferase activity, transferring glycosyl groups
PLUT_RS07170	COG1132	(ABC) transporter
PLUT_RS07185	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PLUT_RS07220	COG2205	protein histidine kinase activity
PLUT_RS07240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PLUT_RS07260	COG2308	Evidence 4 Homologs of previously reported genes of
PLUT_RS07270	COG1305	Transglutaminase-like
PLUT_RS07275	COG0343	queuine tRNA-ribosyltransferase activity
PLUT_RS07280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PLUT_RS07285	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PLUT_RS07290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PLUT_RS07295	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PLUT_RS07305	COG0432	Pfam Uncharacterised protein family UPF0047
PLUT_RS07325	COG1522	sequence-specific DNA binding
PLUT_RS07335	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
PLUT_RS07335	COG0493	'glutamate synthase
PLUT_RS07345	COG2204	response regulator
PLUT_RS07350	COG0756	dUTP diphosphatase activity
PLUT_RS07355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PLUT_RS07370	COG1063	alcohol dehydrogenase
PLUT_RS07375	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
PLUT_RS07380	COG1217	gtp-binding protein TYPA
PLUT_RS07390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PLUT_RS07395	COG0181	hydroxymethylbilane synthase activity
PLUT_RS07400	COG1587	Uroporphyrinogen-III synthase
PLUT_RS07415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PLUT_RS07425	COG0511	ligase activity, forming carbon-carbon bonds
PLUT_RS07430	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
PLUT_RS07435	COG0113	porphobilinogen synthase activity
PLUT_RS07440	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PLUT_RS07455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PLUT_RS07485	COG1966	Carbon starvation protein
PLUT_RS07500	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
PLUT_RS07505	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
PLUT_RS07510	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PLUT_RS07515	COG0310	cobalt ion transport
PLUT_RS07530	COG1122	ATPase activity
PLUT_RS07540	COG0409	Hydrogenase expression formation protein
PLUT_RS07545	COG0298	carbon dioxide binding
PLUT_RS07550	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
PLUT_RS07560	COG0375	protein maturation
PLUT_RS07565	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PLUT_RS07565	COG0731	radical SAM domain protein
PLUT_RS07575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PLUT_RS07580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PLUT_RS07585	COG0149	triose-phosphate isomerase activity
PLUT_RS07595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PLUT_RS07600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PLUT_RS07620	COG0481	GTPase activity
PLUT_RS07625	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PLUT_RS07630	COG0242	peptide deformylase activity
PLUT_RS07640	COG0589	response to stress
PLUT_RS07640	COG0475	glutathione-regulated potassium exporter activity
PLUT_RS07650	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PLUT_RS07655	COG2824	Alkylphosphonate utilization operon protein PhnA
PLUT_RS07660	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PLUT_RS07665	COG1136	(ABC) transporter
PLUT_RS07690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PLUT_RS07700	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
PLUT_RS07705	COG0484	heat shock protein binding
PLUT_RS07710	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PLUT_RS07715	COG1420	regulation of RNA biosynthetic process
PLUT_RS07720	COG2890	protein-(glutamine-N5) methyltransferase activity
PLUT_RS07730	COG0442	prolyl-tRNA aminoacylation
PLUT_RS07735	COG0450	alkyl hydroperoxide reductase
PLUT_RS07740	COG2252	PERMEase
PLUT_RS07750	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PLUT_RS07765	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PLUT_RS07780	COG1132	(ABC) transporter
PLUT_RS07785	COG1032	radical SAM domain protein
PLUT_RS07790	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PLUT_RS07800	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PLUT_RS07810	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PLUT_RS07815	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PLUT_RS07820	COG0039	L-malate dehydrogenase activity
PLUT_RS07830	COG2957	Belongs to the agmatine deiminase family
PLUT_RS07840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PLUT_RS07845	COG1575	Belongs to the MenA family. Type 1 subfamily
PLUT_RS07850	COG0492	ferredoxin-NADP+ reductase activity
PLUT_RS07860	COG0107	imidazoleglycerol-phosphate synthase activity
PLUT_RS07875	COG0598	Magnesium transport protein CorA
PLUT_RS07880	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PLUT_RS07885	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PLUT_RS07890	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PLUT_RS07900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PLUT_RS07915	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
PLUT_RS07925	COG0347	Belongs to the P(II) protein family
PLUT_RS07950	COG1433	Dinitrogenase iron-molybdenum cofactor
PLUT_RS07950	COG0535	radical SAM domain protein
PLUT_RS07970	COG4771	TonB-dependent receptor
PLUT_RS07985	COG4662	Binding-protein-dependent transport system inner membrane component
PLUT_RS07995	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PLUT_RS08010	COG0626	cystathionine gamma-synthase activity
PLUT_RS08035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PLUT_RS08045	COG4208	sulfate ABC transporter
PLUT_RS08050	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PLUT_RS08065	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PLUT_RS08065	COG1648	precorrin-2 dehydrogenase activity
PLUT_RS08075	COG0175	sulfate reduction
PLUT_RS08080	COG0175	sulfate reduction
PLUT_RS08100	COG2022	thiamine diphosphate biosynthetic process
PLUT_RS08110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PLUT_RS08115	COG4232	protein-disulfide reductase activity
PLUT_RS08135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PLUT_RS08145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PLUT_RS08160	COG1846	Transcriptional regulator
PLUT_RS08165	COG0673	inositol 2-dehydrogenase activity
PLUT_RS08170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PLUT_RS08175	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PLUT_RS08195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PLUT_RS08220	COG0811	peptide transport
PLUT_RS08225	COG0358	DNA primase activity
PLUT_RS08230	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PLUT_RS08235	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PLUT_RS08235	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PLUT_RS08240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PLUT_RS08270	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PLUT_RS08275	COG0577	efflux transmembrane transporter activity
PLUT_RS08280	COG0205	6-phosphofructokinase activity
PLUT_RS08285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PLUT_RS08290	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PLUT_RS08295	COG0006	proline dipeptidase activity
PLUT_RS08300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PLUT_RS08305	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PLUT_RS08310	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PLUT_RS08315	COG0328	RNA-DNA hybrid ribonuclease activity
PLUT_RS08325	COG0037	tRNA processing
PLUT_RS08330	COG0688	phosphatidylethanolamine metabolic process
PLUT_RS08335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PLUT_RS08340	COG0497	DNA recombination
PLUT_RS08345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PLUT_RS08350	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PLUT_RS08355	COG0509	glycine decarboxylation via glycine cleavage system
PLUT_RS08360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PLUT_RS08365	COG1013	pyruvate-flavodoxin oxidoreductase activity
PLUT_RS08365	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PLUT_RS08365	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PLUT_RS08365	COG0674	pyruvate-flavodoxin oxidoreductase activity
PLUT_RS08375	COG2255	four-way junction helicase activity
PLUT_RS08380	COG0601	transmembrane transport
PLUT_RS08390	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PLUT_RS08400	COG4974	Belongs to the 'phage' integrase family
PLUT_RS08415	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PLUT_RS08420	COG3245	cytochrome
PLUT_RS08425	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PLUT_RS08435	COG0616	signal peptide processing
PLUT_RS08445	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PLUT_RS08450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PLUT_RS08455	COG1185	polyribonucleotide nucleotidyltransferase activity
PLUT_RS08460	COG0495	leucyl-tRNA aminoacylation
PLUT_RS08465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PLUT_RS08470	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
PLUT_RS08480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PLUT_RS08480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PLUT_RS08485	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PLUT_RS08490	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PLUT_RS08495	COG0217	transcriptional regulatory protein
PLUT_RS08500	COG0077	Prephenate dehydratase
PLUT_RS08500	COG1605	Chorismate mutase
PLUT_RS08505	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PLUT_RS08505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PLUT_RS08510	COG0739	heme binding
PLUT_RS08520	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PLUT_RS08525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PLUT_RS08530	COG0134	indole-3-glycerol-phosphate synthase activity
PLUT_RS08535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PLUT_RS08545	COG0151	Belongs to the GarS family
PLUT_RS08550	COG2121	Domain of unknown function (DUF374)
PLUT_RS08555	COG1663	tetraacyldisaccharide 4'-kinase activity
PLUT_RS08575	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PLUT_RS08580	COG1079	Belongs to the binding-protein-dependent transport system permease family
PLUT_RS08585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PLUT_RS08585	COG0574	Belongs to the PEP-utilizing enzyme family
PLUT_RS08590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PLUT_RS08615	COG0514	ATP-dependent DNA helicase (RecQ)
PLUT_RS08620	COG1032	radical SAM domain protein
PLUT_RS08625	COG1151	hydroxylamine reductase activity
PLUT_RS08660	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PLUT_RS08665	COG1196	nuclear chromosome segregation
PLUT_RS08675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PLUT_RS08680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PLUT_RS08685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PLUT_RS08700	COG0248	Ppx GppA phosphatase
PLUT_RS08710	COG0009	L-threonylcarbamoyladenylate synthase
PLUT_RS08720	COG1187	pseudouridine synthase activity
PLUT_RS08725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PLUT_RS08730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PLUT_RS08735	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PLUT_RS08740	COG0543	2 iron, 2 sulfur cluster binding
PLUT_RS08745	COG0493	'glutamate synthase
PLUT_RS08760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PLUT_RS08765	COG2226	methyltransferase
PLUT_RS08775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PLUT_RS08785	COG1136	(ABC) transporter
PLUT_RS08790	COG0798	PFAM Bile acid sodium symporter
PLUT_RS08795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PLUT_RS08820	COG0725	ABC transporter, periplasmic molybdate-binding protein
PLUT_RS08825	COG4149	molybdate abc transporter
PLUT_RS08830	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PLUT_RS08840	COG3842	ATPase activity
PLUT_RS08870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PLUT_RS08890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PLUT_RS08895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PLUT_RS08920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PLUT_RS08925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PLUT_RS08935	COG0772	Belongs to the SEDS family
PLUT_RS08940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PLUT_RS08950	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PLUT_RS08955	COG0012	GTP binding
PLUT_RS08960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PLUT_RS08965	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PLUT_RS08970	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
PLUT_RS08970	COG0493	'glutamate synthase
PLUT_RS08980	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PLUT_RS08985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PLUT_RS08990	COG1595	DNA-templated transcription, initiation
PLUT_RS09025	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PLUT_RS09030	COG0154	amidase activity
PLUT_RS09035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PLUT_RS09040	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PLUT_RS09055	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PLUT_RS09060	COG2086	electron transfer activity
PLUT_RS09075	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PLUT_RS09080	COG0285	dihydrofolate synthase activity
PLUT_RS09085	COG0632	four-way junction helicase activity
PLUT_RS09090	COG0268	Binds directly to 16S ribosomal RNA
PLUT_RS09095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PLUT_RS09100	COG1132	(ABC) transporter
PLUT_RS09115	COG1304	FMN binding
PLUT_RS09125	COG0758	DNA mediated transformation
PLUT_RS09130	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
PLUT_RS09140	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PLUT_RS09160	COG0194	GDP metabolic process
PLUT_RS09165	COG1561	YicC-like family, N-terminal region
PLUT_RS09170	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PLUT_RS09180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PLUT_RS09185	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PLUT_RS09190	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PLUT_RS09195	COG0195	Participates in both transcription termination and antitermination
PLUT_RS09200	COG0779	Required for maturation of 30S ribosomal subunits
PLUT_RS09235	COG0124	histidyl-tRNA synthetase
PLUT_RS09245	COG0575	Belongs to the CDS family
PLUT_RS09260	COG0859	PFAM glycosyl transferase family 9
PLUT_RS09285	COG0859	PFAM glycosyl transferase family 9
PLUT_RS09310	COG0438	transferase activity, transferring glycosyl groups
PLUT_RS09320	COG1132	(ABC) transporter
PLUT_RS09405	COG2963	transposase activity
PLUT_RS09410	COG3344	reverse transcriptase
PLUT_RS09415	COG2801	Transposase and inactivated derivatives
PLUT_RS09455	COG4584	PFAM Integrase catalytic
PLUT_RS09460	COG1484	DNA-dependent DNA replication
PLUT_RS09540	COG2226	methyltransferase
PLUT_RS09560	COG0367	asparagine synthase
PLUT_RS09600	COG2755	lipolytic protein G-D-S-L family
PLUT_RS09600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PLUT_RS09615	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
PLUT_RS09620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PLUT_RS09720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PLUT_RS09735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PLUT_RS09775	COG3318	Belongs to the UPF0149 family
PLUT_RS09775	COG3012	SEC-C Motif Domain Protein
PLUT_RS09780	COG3012	SEC-C Motif Domain Protein
PLUT_RS09810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PLUT_RS09810	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PLUT_RS09840	COG3177	Filamentation induced by cAMP protein fic
PLUT_RS09855	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PLUT_RS09860	COG1573	uracil-dna glycosylase
PLUT_RS09865	COG0305	Participates in initiation and elongation during chromosome replication
PLUT_RS09870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PLUT_RS09880	COG3550	peptidyl-serine autophosphorylation
PLUT_RS09915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PLUT_RS09920	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PLUT_RS09930	COG0552	protein localization to endoplasmic reticulum
PLUT_RS09955	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PLUT_RS09965	COG4115	mRNA cleavage
PLUT_RS09975	COG0542	response to heat
PLUT_RS09990	COG1797	cobyrinic acid a,c-diamide synthase activity
PLUT_RS10015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PLUT_RS10035	COG0586	Pfam SNARE associated Golgi protein
PLUT_RS10040	COG0596	Alpha beta hydrolase
PLUT_RS10050	COG0519	Catalyzes the synthesis of GMP from XMP
PLUT_RS10050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PLUT_RS10075	COG0446	pyridine nucleotide-disulphide oxidoreductase
PLUT_RS10080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PLUT_RS10090	COG0674	pyruvate-flavodoxin oxidoreductase activity
PLUT_RS10090	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PLUT_RS10095	COG1013	pyruvate-flavodoxin oxidoreductase activity
PLUT_RS10100	COG0825	malonyl-CoA metabolic process
PLUT_RS10110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PLUT_RS10120	COG0439	Biotin carboxylase
PLUT_RS10125	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PLUT_RS10130	COG0085	RNA polymerase activity
PLUT_RS10135	COG0222	ribosome binding
PLUT_RS10140	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PLUT_RS10145	COG0081	regulation of translation
PLUT_RS10150	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PLUT_RS10155	COG0250	Participates in transcription elongation, termination and antitermination
PLUT_RS10160	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PLUT_RS10185	COG1028	Short-chain dehydrogenase reductase Sdr
PLUT_RS10190	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PLUT_RS10200	COG0148	phosphopyruvate hydratase activity
PLUT_RS10205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PLUT_RS10210	COG0463	Glycosyl transferase, family 2
PLUT_RS10225	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PLUT_RS10230	COG1773	rubredoxin
PLUT_RS10235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PLUT_RS10250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PLUT_RS10255	COG1058	Belongs to the CinA family
PLUT_RS10255	COG1546	Belongs to the CinA family
PLUT_RS10265	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PLUT_RS10270	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PLUT_RS10275	COG0083	homoserine kinase activity
PLUT_RS10290	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PLUT_RS10295	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PLUT_RS10300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PLUT_RS10305	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PLUT_RS10310	COG2048	Heterodisulfide reductase, subunit B
PLUT_RS10315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PLUT_RS10320	COG1053	succinate dehydrogenase
PLUT_RS10325	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PLUT_RS10325	COG0517	IMP dehydrogenase activity
PLUT_RS10375	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PLUT_RS10380	COG3876	Protein conserved in bacteria
PLUT_RS10400	COG0745	RESPONSE REGULATOR receiver
PLUT_RS10410	COG0702	epimerase
PLUT_RS10435	COG3158	transport of potassium into the cell
PLUT_RS10440	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PLUT_RS10445	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PLUT_RS10445	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PLUT_RS10455	COG0205	6-phosphofructokinase activity
PLUT_RS10470	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PLUT_RS10475	COG1028	Short-chain dehydrogenase reductase Sdr
PLUT_RS10480	COG3956	TIGRFAM MazG family protein
PLUT_RS10495	COG0366	Alpha amylase catalytic
PLUT_RS10500	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PLUT_RS10530	COG1381	Involved in DNA repair and RecF pathway recombination
PLUT_RS10535	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PLUT_RS10545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PLUT_RS10555	COG0243	molybdopterin cofactor binding
PLUT_RS10565	COG3301	Polysulphide reductase, NrfD
PLUT_RS10575	COG0446	pyridine nucleotide-disulphide oxidoreductase
PLUT_RS10580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PLUT_RS10585	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PLUT_RS10595	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PLUT_RS10610	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PLUT_RS10615	COG0542	response to heat
PLUT_RS10620	COG1472	Belongs to the glycosyl hydrolase 3 family
PLUT_RS10630	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PLUT_RS10635	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PLUT_RS10640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PLUT_RS10645	COG0527	aspartate kinase activity
PLUT_RS10650	COG2264	protein methyltransferase activity
PLUT_RS10655	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PLUT_RS10655	COG0248	Ppx GppA phosphatase
PLUT_RS10665	COG0318	PFAM AMP-dependent synthetase and ligase
PLUT_RS10675	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PLUT_RS10680	COG4106	trans-aconitate 2-methyltransferase activity
PLUT_RS10690	COG0156	8-amino-7-oxononanoate synthase activity
PLUT_RS10695	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PLUT_RS10700	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PLUT_RS10700	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PLUT_RS10705	COG0860	N-Acetylmuramoyl-L-alanine amidase
PLUT_RS10710	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PLUT_RS10715	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PLUT_RS10715	COG1918	ferrous iron import across plasma membrane
PLUT_RS10720	COG1918	ferrous iron import across plasma membrane
PLUT_RS10725	COG0537	adenosine 5'-monophosphoramidase activity
PLUT_RS10730	COG1253	flavin adenine dinucleotide binding
PLUT_RS10750	COG1053	succinate dehydrogenase
PLUT_RS10760	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PLUT_RS10770	COG1785	Belongs to the alkaline phosphatase family
PLUT_RS10775	COG2267	carboxylic ester hydrolase activity
PLUT_RS10785	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PLUT_RS10790	COG1899	peptidyl-lysine modification to peptidyl-hypusine
PLUT_RS10795	COG0180	Tryptophanyl-tRNA synthetase
PLUT_RS10805	COG0018	arginyl-trna synthetase
PLUT_RS10810	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PLUT_RS10825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PLUT_RS10830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PLUT_RS10835	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PLUT_RS10840	COG0356	it plays a direct role in the translocation of protons across the membrane
PLUT_RS10855	COG1496	oxidoreductase activity
PLUT_RS10865	COG2813	Specifically methylates the guanine in position
PLUT_RS10870	COG0427	acetyl-CoA hydrolase
PLUT_RS10890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PLUT_RS10895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PLUT_RS10900	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PLUT_RS10905	COG0772	Belongs to the SEDS family
PLUT_RS10910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PLUT_RS10915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PLUT_RS10920	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PLUT_RS10925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PLUT_RS10930	COG0768	penicillin binding
PLUT_RS10940	COG0275	rRNA processing
PLUT_RS10945	COG2001	Belongs to the MraZ family
PLUT_RS10960	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PLUT_RS10965	COG0126	phosphoglycerate kinase activity
PLUT_RS10980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PLUT_RS10985	COG1940	carbohydrate kinase activity
PLUT_RS10990	COG0671	phosphoesterase, PA-phosphatase related
PLUT_RS10995	COG0706	membrane insertase activity
PLUT_RS11000	COG0594	ribonuclease P activity
PLUT_RS11005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PLUT_RS11010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PLUT_RS11075	COG0438	transferase activity, transferring glycosyl groups
PLUT_RS11095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PLUT_RS11140	COG5002	protein histidine kinase activity
PLUT_RS11155	COG4191	Histidine kinase
PLUT_RS11160	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis