locus-tag	class	description
DK843_RS00060	COG4771	TonB-dependent receptor
DK843_RS00100	COG0747	negative chemotaxis
DK843_RS00145	COG3590	peptidase
DK843_RS00165	COG1199	ATP-dependent helicase activity
DK843_RS00175	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DK843_RS00180	COG0137	argininosuccinate synthase activity
DK843_RS00205	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DK843_RS00210	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DK843_RS00230	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DK843_RS00280	COG2860	membrane
DK843_RS00295	COG0583	DNA-binding transcription factor activity
DK843_RS00300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DK843_RS00320	COG1012	belongs to the aldehyde dehydrogenase family
DK843_RS00330	COG1917	Cupin 2, conserved barrel domain protein
DK843_RS00330	COG1396	sequence-specific DNA binding
DK843_RS00335	COG0686	Belongs to the AlaDH PNT family
DK843_RS00340	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DK843_RS00345	COG0174	glutamine synthetase
DK843_RS00360	COG1360	Flagellar Motor Protein
DK843_RS00375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DK843_RS00380	COG2828	Protein conserved in bacteria
DK843_RS00385	COG0617	tRNA 3'-terminal CCA addition
DK843_RS00395	COG0741	lytic transglycosylase activity
DK843_RS00395	COG1196	nuclear chromosome segregation
DK843_RS00395	COG0739	heme binding
DK843_RS00410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DK843_RS00415	COG0583	DNA-binding transcription factor activity
DK843_RS00420	COG0346	lactoylglutathione lyase activity
DK843_RS00425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DK843_RS00425	COG0678	peroxiredoxin activity
DK843_RS00430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DK843_RS00440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DK843_RS00445	COG0840	transmembrane signaling receptor activity
DK843_RS00455	COG2217	Heavy metal translocating P-type atpase
DK843_RS00460	COG3321	synthase
DK843_RS00460	COG1028	Short-chain dehydrogenase reductase Sdr
DK843_RS00460	COG0604	alcohol dehydrogenase
DK843_RS00470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DK843_RS00470	COG0047	phosphoribosylformylglycinamidine synthase activity
DK843_RS00475	COG0347	Belongs to the P(II) protein family
DK843_RS00480	COG1279	arginine transmembrane transporter activity
DK843_RS00485	COG1666	GTP binding
DK843_RS00495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DK843_RS00510	COG1063	alcohol dehydrogenase
DK843_RS00555	COG3026	antisigma factor binding
DK843_RS00560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DK843_RS00570	COG0481	GTPase activity
DK843_RS00585	COG0571	ribonuclease III activity
DK843_RS00590	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DK843_RS00600	COG1381	Involved in DNA repair and RecF pathway recombination
DK843_RS00605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DK843_RS00610	COG0736	holo-[acyl-carrier-protein] synthase activity
DK843_RS00615	COG1472	Belongs to the glycosyl hydrolase 3 family
DK843_RS00635	COG0456	acetyltransferase
DK843_RS00645	COG1162	GTPase activity
DK843_RS00665	COG1024	Enoyl-CoA hydratase
DK843_RS00670	COG1024	Enoyl-CoA hydratase
DK843_RS00675	COG1960	acyl-CoA dehydrogenase activity
DK843_RS00685	COG1250	3-hydroxyacyl-CoA dehydrogenase
DK843_RS00695	COG0183	Belongs to the thiolase family
DK843_RS00710	COG1309	transcriptional regulator
DK843_RS00715	COG0859	PFAM glycosyl transferase family 9
DK843_RS00730	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DK843_RS00745	COG0312	modulator of DNA gyrase
DK843_RS00750	COG0124	histidyl-tRNA synthetase
DK843_RS00765	COG1473	amidohydrolase
DK843_RS00775	COG0529	Catalyzes the synthesis of activated sulfate
DK843_RS00815	COG3493	citrate carrier protein
DK843_RS00820	COG0066	3-isopropylmalate dehydratase activity
DK843_RS00830	COG0583	DNA-binding transcription factor activity
DK843_RS00845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DK843_RS00855	COG0512	Glutamine amidotransferase of anthranilate synthase
DK843_RS00860	COG1959	2 iron, 2 sulfur cluster binding
DK843_RS00870	COG0446	pyridine nucleotide-disulphide oxidoreductase
DK843_RS00880	COG0546	phosphoglycolate phosphatase activity
DK843_RS00885	COG1028	Short-chain dehydrogenase reductase Sdr
DK843_RS00890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DK843_RS00895	COG2967	ApaG domain
DK843_RS00900	COG5265	(ABC) transporter
DK843_RS00915	COG0346	lactoylglutathione lyase activity
DK843_RS00930	COG1418	mRNA catabolic process
DK843_RS00970	COG0052	Belongs to the universal ribosomal protein uS2 family
DK843_RS00975	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DK843_RS00980	COG0528	UMP kinase activity
DK843_RS00985	COG0233	cytoplasmic translational termination
DK843_RS00990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DK843_RS00995	COG0575	Belongs to the CDS family
DK843_RS01000	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DK843_RS01015	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
DK843_RS01020	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DK843_RS01025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DK843_RS01030	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DK843_RS01035	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DK843_RS01040	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DK843_RS01055	COG0784	Response regulator, receiver
DK843_RS01055	COG2198	Histidine kinase
DK843_RS01055	COG2205	protein histidine kinase activity
DK843_RS01065	COG2199	diguanylate cyclase activity
DK843_RS01065	COG2200	EAL domain
DK843_RS01080	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DK843_RS01100	COG1858	cytochrome C peroxidase
DK843_RS01130	COG1115	amino acid carrier protein
DK843_RS01135	COG3707	response regulator
DK843_RS01140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DK843_RS01145	COG2223	nitrite transmembrane transporter activity
DK843_RS01150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DK843_RS01160	COG0243	molybdopterin cofactor binding
DK843_RS01170	COG4774	siderophore transport
DK843_RS01175	COG2382	esterase
DK843_RS01185	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DK843_RS01185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DK843_RS01215	COG1518	maintenance of DNA repeat elements
DK843_RS01220	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DK843_RS01225	COG1120	ATPase activity
DK843_RS01230	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK843_RS01235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK843_RS01250	COG4592	Periplasmic binding protein
DK843_RS01260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DK843_RS01285	COG1902	pentaerythritol trinitrate reductase activity
DK843_RS01290	COG3493	citrate carrier protein
DK843_RS01305	COG0738	Major facilitator superfamily
DK843_RS01320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DK843_RS01350	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DK843_RS01360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DK843_RS01395	COG2851	Citrate transporter
DK843_RS01405	COG0659	secondary active sulfate transmembrane transporter activity
DK843_RS01445	COG2801	Transposase and inactivated derivatives
DK843_RS01500	COG0776	regulation of translation
DK843_RS01555	COG4383	Mu-like prophage protein gp29
DK843_RS01580	COG4397	Mu-like prophage major head subunit gpT
DK843_RS01650	COG3299	homolog of phage Mu protein gp47
DK843_RS01670	COG4133	protoheme IX ABC transporter activity
DK843_RS01675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DK843_RS01680	COG1752	Esterase of the alpha-beta hydrolase superfamily
DK843_RS01690	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DK843_RS01725	COG3568	Endonuclease Exonuclease Phosphatase
DK843_RS01735	COG2011	ABC-type metal ion transport system permease component
DK843_RS01760	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DK843_RS01775	COG1619	proteins homologs of microcin C7 resistance protein MccF
DK843_RS01785	COG0175	sulfate reduction
DK843_RS01790	COG2895	sulfate adenylyltransferase (ATP) activity
DK843_RS01800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK843_RS01800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK843_RS01800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK843_RS01805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK843_RS01810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK843_RS01810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK843_RS01810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DK843_RS01820	COG2207	Transcriptional regulator
DK843_RS01840	COG0497	DNA recombination
DK843_RS01845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DK843_RS01860	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DK843_RS01865	COG0123	including yeast histone deacetylase and acetoin utilization protein
DK843_RS01885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DK843_RS01895	COG0488	(ABC) transporter
DK843_RS01905	COG0024	Methionine aminopeptidase
DK843_RS01910	COG2378	regulation of single-species biofilm formation
DK843_RS01920	COG0237	dephospho-CoA kinase activity
DK843_RS01920	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DK843_RS01950	COG1435	thymidine kinase activity
DK843_RS01960	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DK843_RS01970	COG1744	ABC transporter substrate-binding protein PnrA-like
DK843_RS01975	COG3845	ABC transporter
DK843_RS01980	COG4603	Belongs to the binding-protein-dependent transport system permease family
DK843_RS01985	COG1079	Belongs to the binding-protein-dependent transport system permease family
DK843_RS01990	COG0303	'Molybdopterin
DK843_RS02005	COG0628	permease
DK843_RS02040	COG1573	uracil-dna glycosylase
DK843_RS02045	COG2070	2-Nitropropane dioxygenase
DK843_RS02050	COG0302	gtp cyclohydrolase
DK843_RS02055	COG0545	Peptidyl-prolyl cis-trans isomerase
DK843_RS02060	COG1956	GAF domain-containing protein
DK843_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
DK843_RS02075	COG2154	pterin-4-alpha-carbinolamine dehydratase
DK843_RS02080	COG0501	Belongs to the peptidase M48B family
DK843_RS02085	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DK843_RS02090	COG0166	Belongs to the GPI family
DK843_RS02105	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DK843_RS02110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DK843_RS02140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DK843_RS02145	COG0733	neurotransmitter:sodium symporter activity
DK843_RS02175	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DK843_RS02180	COG1629	transport
DK843_RS02185	COG0307	riboflavin synthase, alpha
DK843_RS02200	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DK843_RS02205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DK843_RS02210	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DK843_RS02215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DK843_RS02225	COG0443	Heat shock 70 kDa protein
DK843_RS02230	COG4974	Belongs to the 'phage' integrase family
DK843_RS02235	COG0024	Methionine aminopeptidase
DK843_RS02270	COG1187	pseudouridine synthase activity
DK843_RS02285	COG1217	gtp-binding protein TYPA
DK843_RS02300	COG0602	queuosine metabolic process
DK843_RS02310	COG2814	Major facilitator Superfamily
DK843_RS02350	COG0625	glutathione transferase activity
DK843_RS02355	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DK843_RS02365	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DK843_RS02375	COG0583	DNA-binding transcription factor activity
DK843_RS02380	COG1049	propionate catabolic process, 2-methylcitrate cycle
DK843_RS02395	COG1744	ABC transporter substrate-binding protein PnrA-like
DK843_RS02405	COG1695	Transcriptional regulator
DK843_RS02410	COG0840	transmembrane signaling receptor activity
DK843_RS02420	COG1988	membrane-bound metal-dependent
DK843_RS02425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DK843_RS02430	COG1131	(ABC) transporter
DK843_RS02435	COG0842	Transport permease protein
DK843_RS02445	COG1309	transcriptional regulator
DK843_RS02450	COG0534	Mate efflux family protein
DK843_RS02510	COG1181	Belongs to the D-alanine--D-alanine ligase family
DK843_RS02535	COG0739	heme binding
DK843_RS02540	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DK843_RS02545	COG1674	ftsk spoiiie
DK843_RS02550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DK843_RS02560	COG1309	transcriptional regulator
DK843_RS02565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DK843_RS02570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DK843_RS02575	COG0300	oxidoreductase activity
DK843_RS02585	COG1309	transcriptional regulator
DK843_RS02605	COG1024	Enoyl-CoA hydratase
DK843_RS02645	COG1764	response to oxidative stress
DK843_RS02655	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DK843_RS02660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DK843_RS02680	COG3411	Ferredoxin
DK843_RS02690	COG2081	HI0933 family
DK843_RS02695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DK843_RS02720	COG0285	dihydrofolate synthase activity
DK843_RS02735	COG0488	(ABC) transporter
DK843_RS02750	COG0791	NLP P60 protein
DK843_RS02765	COG1595	DNA-templated transcription, initiation
DK843_RS02775	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DK843_RS02795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DK843_RS02800	COG1763	Mo-molybdopterin cofactor biosynthetic process
DK843_RS02805	COG3850	Histidine kinase
DK843_RS02810	COG2197	response regulator
DK843_RS02820	COG2181	nitrate reductase activity
DK843_RS02825	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DK843_RS02830	COG1140	nitrate reductase beta subunit
DK843_RS02835	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DK843_RS02840	COG2223	nitrite transmembrane transporter activity
DK843_RS02855	COG3008	intermembrane lipid transfer
DK843_RS02855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DK843_RS02860	COG2995	paraquat-inducible protein a
DK843_RS02885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DK843_RS02905	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DK843_RS02910	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DK843_RS02915	COG0740	serine-type endopeptidase activity
DK843_RS02920	COG0544	peptidyl-prolyl cis-trans isomerase activity
DK843_RS02945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK843_RS02960	COG4221	oxidoreductase activity
DK843_RS02965	COG0583	DNA-binding transcription factor activity
DK843_RS02975	COG5001	Diguanylate cyclase
DK843_RS03000	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DK843_RS03005	COG3447	MASE1 domain protein
DK843_RS03005	COG5001	Diguanylate cyclase
DK843_RS03005	COG5002	protein histidine kinase activity
DK843_RS03010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DK843_RS03015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DK843_RS03030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK843_RS03115	COG2207	Transcriptional regulator
DK843_RS03155	COG3850	Histidine kinase
DK843_RS03155	COG3437	response regulator, receiver
DK843_RS03155	COG2205	protein histidine kinase activity
DK843_RS03155	COG4999	Histidine kinase
DK843_RS03160	COG0745	RESPONSE REGULATOR receiver
DK843_RS03170	COG0840	transmembrane signaling receptor activity
DK843_RS03175	COG3048	D-serine ammonia-lyase activity
DK843_RS03180	COG0583	DNA-binding transcription factor activity
DK843_RS03225	COG0387	Pfam Sodium calcium exchanger
DK843_RS03250	COG0525	valine-tRNA ligase activity
DK843_RS03275	COG2194	sulfuric ester hydrolase activity
DK843_RS03290	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DK843_RS03295	COG1215	transferase activity, transferring glycosyl groups
DK843_RS03320	COG0583	DNA-binding transcription factor activity
DK843_RS03335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DK843_RS03345	COG4166	transmembrane transport
DK843_RS03350	COG0300	oxidoreductase activity
DK843_RS03355	COG1722	exodeoxyribonuclease VII activity
DK843_RS03360	COG0142	geranyltranstransferase activity
DK843_RS03365	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DK843_RS03380	COG2195	Cleaves the N-terminal amino acid of tripeptides
DK843_RS03400	COG1309	transcriptional regulator
DK843_RS03415	COG0577	efflux transmembrane transporter activity
DK843_RS03415	COG1136	(ABC) transporter
DK843_RS03420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DK843_RS03425	COG0384	phenazine biosynthesis protein PhzF
DK843_RS03460	COG0134	indole-3-glycerol-phosphate synthase activity
DK843_RS03465	COG5380	lipid catabolic process
DK843_RS03470	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DK843_RS03475	COG1752	Esterase of the alpha-beta hydrolase superfamily
DK843_RS03495	COG0183	Belongs to the thiolase family
DK843_RS03500	COG1024	Enoyl-CoA hydratase
DK843_RS03500	COG1250	3-hydroxyacyl-CoA dehydrogenase
DK843_RS03515	COG1960	acyl-CoA dehydrogenase activity
DK843_RS03540	COG1454	alcohol dehydrogenase
DK843_RS03545	COG2095	MarC family integral membrane protein
DK843_RS03550	COG0833	amino acid
DK843_RS03555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DK843_RS03560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DK843_RS03610	COG0625	glutathione transferase activity
DK843_RS03615	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DK843_RS03620	COG2226	methyltransferase
DK843_RS03685	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DK843_RS03690	COG1765	OsmC-like protein
DK843_RS03695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DK843_RS03700	COG0488	(ABC) transporter
DK843_RS03710	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DK843_RS03715	COG0159	tryptophan synthase activity
DK843_RS03720	COG0133	tryptophan synthase activity
DK843_RS03730	COG0101	tRNA pseudouridine synthase activity
DK843_RS03770	COG0473	3-isopropylmalate dehydrogenase activity
DK843_RS03790	COG0066	3-isopropylmalate dehydratase activity
DK843_RS03800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DK843_RS03820	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DK843_RS03825	COG0179	Fumarylacetoacetate (FAA) hydrolase
DK843_RS03830	COG3243	poly(R)-hydroxyalkanoic acid synthase
DK843_RS03835	COG0183	Belongs to the thiolase family
DK843_RS03855	COG0789	Transcriptional regulator
DK843_RS03860	COG0655	NAD(P)H dehydrogenase (quinone) activity
DK843_RS03870	COG0006	proline dipeptidase activity
DK843_RS03875	COG0583	DNA-binding transcription factor activity
DK843_RS03900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DK843_RS03910	COG1028	Short-chain dehydrogenase reductase Sdr
DK843_RS03935	COG0492	ferredoxin-NADP+ reductase activity
DK843_RS03945	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DK843_RS03950	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DK843_RS03960	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DK843_RS03965	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DK843_RS03980	COG0784	Response regulator, receiver
DK843_RS03990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DK843_RS04025	COG1566	PFAM secretion protein HlyD family protein
DK843_RS04045	COG0513	Belongs to the DEAD box helicase family
DK843_RS04055	COG2175	clavaminate synthase activity
DK843_RS04060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DK843_RS04065	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DK843_RS04070	COG4521	taurine ABC transporter
DK843_RS04080	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DK843_RS04090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DK843_RS04105	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DK843_RS04115	COG1760	l-serine dehydratase
DK843_RS04125	COG1166	arginine decarboxylase activity
DK843_RS04130	COG2988	succinylglutamate desuccinylase activity
DK843_RS04135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DK843_RS04145	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK843_RS04145	COG3951	Flagellar rod assembly protein muramidase FlgJ
DK843_RS04150	COG1706	bacterial-type flagellum-dependent cell motility
DK843_RS04155	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DK843_RS04170	COG1749	Flagellar hook protein flgE
DK843_RS04200	COG2200	EAL domain
DK843_RS04205	COG0513	Belongs to the DEAD box helicase family
DK843_RS04245	COG0395	ABC-type sugar transport system, permease component
DK843_RS04255	COG0477	Major facilitator Superfamily
DK843_RS04260	COG3228	Belongs to the MtfA family
DK843_RS04270	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DK843_RS04275	COG2816	NAD+ diphosphatase activity
DK843_RS04320	COG2096	Adenosyltransferase
DK843_RS04335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DK843_RS04350	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DK843_RS04375	COG0516	GMP reductase activity
DK843_RS04385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DK843_RS04395	COG1739	Uncharacterized protein family UPF0029
DK843_RS04410	COG2917	probably involved in intracellular septation
DK843_RS04415	COG2350	Protein conserved in bacteria
DK843_RS04425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DK843_RS04430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DK843_RS04435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DK843_RS04445	COG1017	nitric oxide dioxygenase activity
DK843_RS04445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DK843_RS04460	COG0583	DNA-binding transcription factor activity
DK843_RS04465	COG0121	glutamine amidotransferase
DK843_RS04485	COG0840	transmembrane signaling receptor activity
DK843_RS04505	COG0456	acetyltransferase
DK843_RS04525	COG1609	Transcriptional regulator
DK843_RS04530	COG3265	gluconokinase activity
DK843_RS04535	COG2271	Major facilitator Superfamily
DK843_RS04550	COG4566	intracellular signal transduction
DK843_RS04555	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DK843_RS04555	COG3264	Mechanosensitive ion channel
DK843_RS04560	COG1136	(ABC) transporter
DK843_RS04575	COG0791	NLP P60 protein
DK843_RS04590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK843_RS04605	COG1595	DNA-templated transcription, initiation
DK843_RS04620	COG1028	Short-chain dehydrogenase reductase Sdr
DK843_RS04625	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DK843_RS04630	COG1562	ergosterol biosynthetic process
DK843_RS04635	COG1562	ergosterol biosynthetic process
DK843_RS04650	COG1126	abc transporter atp-binding protein
DK843_RS04655	COG0765	amino acid transport
DK843_RS04660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK843_RS04705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DK843_RS04710	COG1360	Flagellar Motor Protein
DK843_RS04715	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DK843_RS04720	COG1191	sigma factor activity
DK843_RS04775	COG1677	Flagellar hook-basal body complex protein FliE
DK843_RS04795	COG1987	bacterial-type flagellum assembly
DK843_RS04825	COG2205	protein histidine kinase activity
DK843_RS04825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK843_RS04835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DK843_RS04870	COG1879	ABC-type sugar transport system periplasmic component
DK843_RS04875	COG1172	Belongs to the binding-protein-dependent transport system permease family
DK843_RS04880	COG1129	ABC transporter
DK843_RS04885	COG1869	D-ribose catabolic process
DK843_RS04890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DK843_RS04900	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DK843_RS04910	COG0625	glutathione transferase activity
DK843_RS04920	COG1620	l-lactate permease
DK843_RS04925	COG0277	FAD linked oxidase domain protein
DK843_RS04930	COG1139	Iron-sulfur cluster binding protein
DK843_RS04940	COG0247	lactate metabolic process
DK843_RS04950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DK843_RS04955	COG0798	PFAM Bile acid sodium symporter
DK843_RS04965	COG0835	chemotaxis
DK843_RS04965	COG0784	Response regulator, receiver
DK843_RS05000	COG3039	Transposase
DK843_RS05010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DK843_RS05020	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DK843_RS05020	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DK843_RS05030	COG0284	orotidine-5'-phosphate decarboxylase activity
DK843_RS05035	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DK843_RS05045	COG0776	regulation of translation
DK843_RS05055	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DK843_RS05060	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DK843_RS05070	COG3038	cytochrome b561
DK843_RS05075	COG1609	Transcriptional regulator
DK843_RS05080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DK843_RS05080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK843_RS05085	COG1105	Belongs to the carbohydrate kinase PfkB family
DK843_RS05090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK843_RS05090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK843_RS05095	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DK843_RS05125	COG1024	Enoyl-CoA hydratase
DK843_RS05140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DK843_RS05155	COG0523	cobalamin synthesis protein
DK843_RS05160	COG0735	belongs to the Fur family
DK843_RS05190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DK843_RS05205	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DK843_RS05210	COG2226	methyltransferase
DK843_RS05215	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DK843_RS05220	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DK843_RS05225	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DK843_RS05230	COG2951	lytic endotransglycosylase activity
DK843_RS05235	COG1420	regulation of RNA biosynthetic process
DK843_RS05240	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DK843_RS05245	COG2137	regulation of response to DNA damage stimulus
DK843_RS05255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DK843_RS05280	COG0730	response to heat
DK843_RS05300	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DK843_RS05305	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DK843_RS05310	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DK843_RS05315	COG2205	protein histidine kinase activity
DK843_RS05320	COG0745	RESPONSE REGULATOR receiver
DK843_RS05330	COG0534	Mate efflux family protein
DK843_RS05335	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DK843_RS05365	COG0494	nUDIX hydrolase
DK843_RS05370	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DK843_RS05405	COG1492	cobalamin metabolic process
DK843_RS05410	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DK843_RS05420	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DK843_RS05425	COG3411	Ferredoxin
DK843_RS05450	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
DK843_RS05455	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DK843_RS05485	COG1120	ATPase activity
DK843_RS05495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK843_RS05505	COG1797	cobyrinic acid a,c-diamide synthase activity
DK843_RS05510	COG0778	Nitroreductase
DK843_RS05515	COG2755	lipolytic protein G-D-S-L family
DK843_RS05525	COG1024	Enoyl-CoA hydratase
DK843_RS05560	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DK843_RS05590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DK843_RS05600	COG0506	proline dehydrogenase activity
DK843_RS05600	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DK843_RS05600	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DK843_RS05605	COG4221	oxidoreductase activity
DK843_RS05610	COG2814	Major facilitator Superfamily
DK843_RS05660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DK843_RS05665	COG1686	Belongs to the peptidase S11 family
DK843_RS05670	COG2921	Belongs to the UPF0250 family
DK843_RS05675	COG0321	lipoyl(octanoyl) transferase activity
DK843_RS05680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DK843_RS05705	COG0028	Belongs to the TPP enzyme family
DK843_RS05710	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
DK843_RS05715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DK843_RS05740	COG0501	Belongs to the peptidase M48B family
DK843_RS05745	COG0583	DNA-binding transcription factor activity
DK843_RS05750	COG4969	Belongs to the N-Me-Phe pilin family
DK843_RS05790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DK843_RS05795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DK843_RS05800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DK843_RS05805	COG0006	proline dipeptidase activity
DK843_RS05810	COG0217	transcriptional regulatory protein
DK843_RS05840	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DK843_RS05875	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DK843_RS05880	COG1766	The M ring may be actively involved in energy transduction
DK843_RS05885	COG1677	Flagellar hook-basal body complex protein FliE
DK843_RS05895	COG2201	protein-glutamate methylesterase activity
DK843_RS05900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DK843_RS05910	COG0583	DNA-binding transcription factor activity
DK843_RS05930	COG2204	response regulator
DK843_RS05950	COG0556	nucleotide-excision repair
DK843_RS05955	COG1686	Belongs to the peptidase S11 family
DK843_RS05960	COG0583	DNA-binding transcription factor activity
DK843_RS05975	COG1881	PFAM PEBP family protein
DK843_RS05995	COG3842	ATPase activity
DK843_RS06040	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DK843_RS06045	COG1984	allophanate hydrolase subunit 2
DK843_RS06050	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DK843_RS06065	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DK843_RS06070	COG3186	Phenylalanine-4-hydroxylase
DK843_RS06100	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DK843_RS06145	COG0037	tRNA processing
DK843_RS06150	COG0825	malonyl-CoA metabolic process
DK843_RS06225	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DK843_RS06245	COG0312	modulator of DNA gyrase
DK843_RS06250	COG3028	Belongs to the UPF0307 family
DK843_RS06255	COG0521	Mo-molybdopterin cofactor biosynthetic process
DK843_RS06260	COG0429	hydrolase of the alpha beta-hydrolase fold
DK843_RS06280	COG0412	Dienelactone hydrolase
DK843_RS06290	COG1278	Cold shock
DK843_RS06315	COG0406	alpha-ribazole phosphatase activity
DK843_RS06320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DK843_RS06325	COG1047	Peptidyl-prolyl cis-trans
DK843_RS06345	COG1522	sequence-specific DNA binding
DK843_RS06360	COG1280	lysine exporter protein (LysE YggA)
DK843_RS06385	COG2239	Acts as a magnesium transporter
DK843_RS06400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DK843_RS06415	COG1741	Belongs to the pirin family
DK843_RS06425	COG3291	Pkd domain containing protein
DK843_RS06435	COG0583	DNA-binding transcription factor activity
DK843_RS06440	COG2957	Belongs to the agmatine deiminase family
DK843_RS06445	COG3920	Histidine kinase
DK843_RS06505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DK843_RS06510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DK843_RS06515	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DK843_RS06520	COG1231	oxidoreductase activity
DK843_RS06530	COG2353	YceI-like domain
DK843_RS06540	COG3038	cytochrome b561
DK843_RS06555	COG3162	membrane
DK843_RS06560	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DK843_RS06565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DK843_RS06720	COG2369	cell adhesion
DK843_RS06730	COG4373	Mu-like prophage FluMu protein gp28
DK843_RS06750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DK843_RS06805	COG3409	Peptidoglycan-binding domain 1 protein
DK843_RS06805	COG3267	Type II secretory pathway component ExeA
DK843_RS06830	COG0776	regulation of translation
DK843_RS06850	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DK843_RS06855	COG0583	DNA-binding transcription factor activity
DK843_RS06860	COG2878	Part of a membrane complex involved in electron transport
DK843_RS06865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DK843_RS06870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DK843_RS06880	COG0531	amino acid
DK843_RS06895	COG0366	Alpha amylase catalytic
DK843_RS06900	COG1263	PTS System
DK843_RS06900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK843_RS06910	COG2188	Transcriptional regulator
DK843_RS06915	COG0583	DNA-binding transcription factor activity
DK843_RS06920	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DK843_RS06930	COG0625	glutathione transferase activity
DK843_RS06955	COG2841	Protein conserved in bacteria
DK843_RS06960	COG0330	HflC and HflK could
DK843_RS06965	COG0330	HflC and HflK could
DK843_RS06975	COG0861	Integral membrane protein TerC family
DK843_RS07005	COG0840	transmembrane signaling receptor activity
DK843_RS07010	COG0840	transmembrane signaling receptor activity
DK843_RS07050	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DK843_RS07060	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DK843_RS07065	COG1137	ATPase activity
DK843_RS07070	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DK843_RS07075	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DK843_RS07085	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DK843_RS07090	COG1660	Displays ATPase and GTPase activities
DK843_RS07095	COG0163	prenyltransferase activity
DK843_RS07100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DK843_RS07100	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DK843_RS07110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK843_RS07110	COG4191	Histidine kinase
DK843_RS07115	COG0784	Response regulator, receiver
DK843_RS07115	COG3437	response regulator, receiver
DK843_RS07120	COG1272	protein, Hemolysin III
DK843_RS07125	COG0563	adenylate kinase activity
DK843_RS07130	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DK843_RS07135	COG2835	tetraacyldisaccharide 4'-kinase activity
DK843_RS07140	COG1663	tetraacyldisaccharide 4'-kinase activity
DK843_RS07145	COG0848	biopolymer transport protein
DK843_RS07150	COG0811	peptide transport
DK843_RS07165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DK843_RS07175	COG0793	Belongs to the peptidase S41A family
DK843_RS07180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DK843_RS07180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DK843_RS07185	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DK843_RS07200	COG0488	(ABC) transporter
DK843_RS07220	COG0861	Integral membrane protein TerC family
DK843_RS07240	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
DK843_RS07245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DK843_RS07250	COG1053	succinate dehydrogenase
DK843_RS07255	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DK843_RS07260	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DK843_RS07265	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DK843_RS07280	COG0850	regulation of cytokinetic process
DK843_RS07290	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DK843_RS07295	COG0583	DNA-binding transcription factor activity
DK843_RS07330	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DK843_RS07340	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DK843_RS07360	COG0251	oxidation-reduction process
DK843_RS07365	COG0626	cystathionine gamma-synthase activity
DK843_RS07370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DK843_RS07375	COG4106	trans-aconitate 2-methyltransferase activity
DK843_RS07410	COG0482	sulfurtransferase activity
DK843_RS07440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DK843_RS07450	COG2814	Major facilitator Superfamily
DK843_RS07455	COG0583	DNA-binding transcription factor activity
DK843_RS07465	COG0287	Prephenate dehydrogenase
DK843_RS07485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DK843_RS07490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DK843_RS07495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK843_RS07500	COG1028	Short-chain dehydrogenase reductase Sdr
DK843_RS07505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DK843_RS07510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DK843_RS07515	COG0416	fatty acid biosynthetic process
DK843_RS07520	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DK843_RS07525	COG1399	metal-binding, possibly nucleic acid-binding protein
DK843_RS07530	COG0424	maF-like protein
DK843_RS07540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DK843_RS07565	COG0747	negative chemotaxis
DK843_RS07570	COG3300	MHYT domain
DK843_RS07570	COG5001	Diguanylate cyclase
DK843_RS07580	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DK843_RS07580	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DK843_RS07585	COG0509	glycine decarboxylation via glycine cleavage system
DK843_RS07590	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DK843_RS07595	COG0531	amino acid
DK843_RS07600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DK843_RS07610	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DK843_RS07615	COG2201	protein-glutamate methylesterase activity
DK843_RS07625	COG0840	transmembrane signaling receptor activity
DK843_RS07635	COG0643	Histidine kinase
DK843_RS07635	COG2198	Histidine kinase
DK843_RS07650	COG3852	Histidine kinase
DK843_RS07655	COG0835	chemotaxis
DK843_RS07655	COG0784	Response regulator, receiver
DK843_RS07660	COG0784	Response regulator, receiver
DK843_RS07660	COG0835	chemotaxis
DK843_RS07665	COG0745	RESPONSE REGULATOR receiver
DK843_RS07670	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DK843_RS07680	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DK843_RS07690	COG0456	acetyltransferase
DK843_RS07695	COG1573	uracil-dna glycosylase
DK843_RS07700	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DK843_RS07705	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DK843_RS07710	COG0504	CTP synthase activity
DK843_RS07715	COG0148	phosphopyruvate hydratase activity
DK843_RS07720	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DK843_RS07730	COG2914	Belongs to the UPF0125 (RnfH) family
DK843_RS07735	COG2867	negative regulation of translational initiation
DK843_RS07740	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DK843_RS07750	COG0519	Catalyzes the synthesis of GMP from XMP
DK843_RS07750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DK843_RS07780	COG0590	tRNA wobble adenosine to inosine editing
DK843_RS07785	COG1376	ErfK ybiS ycfS ynhG family protein
DK843_RS07820	COG0415	Belongs to the DNA photolyase family
DK843_RS07825	COG0583	DNA-binding transcription factor activity
DK843_RS07840	COG1742	UPF0060 membrane protein
DK843_RS07855	COG1017	nitric oxide dioxygenase activity
DK843_RS07855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DK843_RS07860	COG3397	chitin binding
DK843_RS07895	COG1309	transcriptional regulator
DK843_RS07900	COG0778	Nitroreductase
DK843_RS07905	COG1902	pentaerythritol trinitrate reductase activity
DK843_RS07910	COG1309	transcriptional regulator
DK843_RS07920	COG1505	serine-type exopeptidase activity
DK843_RS07935	COG0745	RESPONSE REGULATOR receiver
DK843_RS07940	COG4104	PAAR repeat-containing protein
DK843_RS07945	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DK843_RS07950	COG0720	synthase
DK843_RS07955	COG0602	queuosine metabolic process
DK843_RS07970	COG3220	belongs to the UPF0276 family
DK843_RS07985	COG0560	Phosphoserine phosphatase
DK843_RS08005	COG4689	acetoacetate decarboxylase
DK843_RS08015	COG0673	inositol 2-dehydrogenase activity
DK843_RS08070	COG0642	Histidine kinase
DK843_RS08080	COG1840	ABC-type Fe3 transport system, periplasmic component
DK843_RS08085	COG4208	sulfate ABC transporter
DK843_RS08090	COG3842	ATPase activity
DK843_RS08095	COG0477	Major facilitator Superfamily
DK843_RS08120	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DK843_RS08125	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DK843_RS08130	COG0330	HflC and HflK could
DK843_RS08135	COG0330	HflC and HflK could
DK843_RS08140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DK843_RS08145	COG1923	regulation of RNA biosynthetic process
DK843_RS08150	COG1160	GTP binding
DK843_RS08155	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DK843_RS08165	COG0124	histidyl-tRNA synthetase
DK843_RS08170	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DK843_RS08185	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DK843_RS08190	COG0105	UTP biosynthetic process
DK843_RS08210	COG2807	transmembrane transport
DK843_RS08220	COG1022	Amp-dependent synthetase and ligase
DK843_RS08230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DK843_RS08235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DK843_RS08280	COG0582	viral genome integration into host DNA
DK843_RS08300	COG2974	May be involved in recombination
DK843_RS08305	COG0753	catalase activity
DK843_RS08310	COG3384	dioxygenase
DK843_RS08315	COG0167	dihydroorotate dehydrogenase activity
DK843_RS08320	COG2193	ferroxidase activity
DK843_RS08325	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DK843_RS08335	COG0717	Belongs to the dCTP deaminase family
DK843_RS08340	COG0386	Belongs to the glutathione peroxidase family
DK843_RS08360	COG3012	SEC-C Motif Domain Protein
DK843_RS08375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DK843_RS08380	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DK843_RS08385	COG1570	exodeoxyribonuclease VII activity
DK843_RS08400	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DK843_RS08405	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DK843_RS08410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DK843_RS08415	COG0196	riboflavin kinase activity
DK843_RS08430	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DK843_RS08435	COG0175	sulfate reduction
DK843_RS08440	COG0583	DNA-binding transcription factor activity
DK843_RS08445	COG1028	Short-chain dehydrogenase reductase Sdr
DK843_RS08450	COG0488	(ABC) transporter
DK843_RS08455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DK843_RS08460	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DK843_RS08470	COG2850	peptidyl-arginine hydroxylation
DK843_RS08490	COG2239	Acts as a magnesium transporter
DK843_RS08495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK843_RS08500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DK843_RS08510	COG0174	glutamine synthetase
DK843_RS08515	COG3681	Belongs to the UPF0597 family
DK843_RS08520	COG0814	amino acid
DK843_RS08525	COG2964	Protein conserved in bacteria
DK843_RS08535	COG3852	Histidine kinase
DK843_RS08560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DK843_RS08590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DK843_RS08605	COG1380	Effector of murein hydrolase LrgA
DK843_RS08610	COG3161	chorismate lyase activity
DK843_RS08615	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DK843_RS08630	COG0494	nUDIX hydrolase
DK843_RS08650	COG0628	permease
DK843_RS08655	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DK843_RS08660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DK843_RS08670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DK843_RS08670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DK843_RS08675	COG0038	chloride channel
DK843_RS08680	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DK843_RS08685	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DK843_RS08705	COG0583	DNA-binding transcription factor activity
DK843_RS08710	COG1247	-acetyltransferase
DK843_RS08720	COG1247	-acetyltransferase
DK843_RS08735	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DK843_RS08740	COG0456	acetyltransferase
DK843_RS08745	COG0359	binds to the 23S rRNA
DK843_RS08750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DK843_RS08760	COG0360	Binds together with S18 to 16S ribosomal RNA
DK843_RS08770	COG1937	Protein conserved in bacteria
DK843_RS08795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DK843_RS08800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DK843_RS08810	COG1115	amino acid carrier protein
DK843_RS08820	COG0584	glycerophosphoryl diester phosphodiesterase
DK843_RS08825	COG3842	ATPase activity
DK843_RS08830	COG0395	ABC-type sugar transport system, permease component
DK843_RS08835	COG1175	transmembrane transport
DK843_RS08840	COG1653	transport
DK843_RS08845	COG1294	oxidase, subunit
DK843_RS08850	COG1271	oxidase subunit
DK843_RS08865	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DK843_RS08895	COG1278	Cold shock
DK843_RS08900	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DK843_RS08905	COG0542	response to heat
DK843_RS08915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DK843_RS08920	COG0335	large ribosomal subunit rRNA binding
DK843_RS08925	COG0336	Belongs to the RNA methyltransferase TrmD family
DK843_RS08930	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DK843_RS08935	COG0228	four-way junction DNA binding
DK843_RS08945	COG1230	cation diffusion facilitator family transporter
DK843_RS08950	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DK843_RS08955	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DK843_RS08960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DK843_RS08970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DK843_RS08985	COG0714	Associated with various cellular activities
DK843_RS08990	COG0123	including yeast histone deacetylase and acetoin utilization protein
DK843_RS08995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DK843_RS09015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DK843_RS09025	COG0316	Belongs to the HesB IscA family
DK843_RS09030	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DK843_RS09035	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DK843_RS09040	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DK843_RS09045	COG0813	purine-nucleoside phosphorylase activity
DK843_RS09050	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DK843_RS09055	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DK843_RS09060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DK843_RS09065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DK843_RS09080	COG2095	MarC family integral membrane protein
DK843_RS09090	COG1301	dicarboxylic acid transport
DK843_RS09110	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DK843_RS09115	COG0023	Translation Initiation Factor
DK843_RS09140	COG3045	CreA protein
DK843_RS09145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DK843_RS09145	COG0321	lipoyl(octanoyl) transferase activity
DK843_RS09155	COG0084	hydrolase, TatD family'
DK843_RS09170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DK843_RS09175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DK843_RS09205	COG2186	Transcriptional regulator
DK843_RS09210	COG2807	transmembrane transport
DK843_RS09220	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DK843_RS09225	COG4181	ATPase activity
DK843_RS09250	COG0450	alkyl hydroperoxide reductase
DK843_RS09255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DK843_RS09270	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DK843_RS09280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DK843_RS09285	COG0505	Belongs to the CarA family
DK843_RS09290	COG0268	Binds directly to 16S ribosomal RNA
DK843_RS09305	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DK843_RS09305	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DK843_RS09310	COG0564	pseudouridine synthase activity
DK843_RS09320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DK843_RS09325	COG2258	MOSC domain
DK843_RS09330	COG3104	oligopeptide transport
DK843_RS09335	COG0583	DNA-binding transcription factor activity
DK843_RS09350	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DK843_RS09405	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DK843_RS09410	COG0114	fumarate hydratase activity
DK843_RS09445	COG1610	YqeY-like protein
DK843_RS09450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DK843_RS09455	COG2022	thiamine diphosphate biosynthetic process
DK843_RS09465	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DK843_RS09470	COG1758	RNA polymerase activity
DK843_RS09475	COG0194	GDP metabolic process
DK843_RS09480	COG2252	PERMEase
DK843_RS09485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DK843_RS09505	COG1695	Transcriptional regulator
DK843_RS09520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DK843_RS09525	COG2235	arginine
DK843_RS09540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DK843_RS09540	COG0543	2 iron, 2 sulfur cluster binding
DK843_RS09550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DK843_RS09555	COG0386	Belongs to the glutathione peroxidase family
DK843_RS09565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DK843_RS09580	COG0586	Pfam SNARE associated Golgi protein
DK843_RS09585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DK843_RS09600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DK843_RS09610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DK843_RS09615	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DK843_RS09620	COG1534	Rna-binding protein
DK843_RS09710	COG1960	acyl-CoA dehydrogenase activity
DK843_RS09725	COG2030	dehydratase
DK843_RS09735	COG0802	atpase or kinase
DK843_RS09740	COG0860	N-Acetylmuramoyl-L-alanine amidase
DK843_RS09745	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DK843_RS09750	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
DK843_RS09755	COG0237	dephospho-CoA kinase activity
DK843_RS09780	COG1596	polysaccharide export
DK843_RS09780	COG1555	photosystem II stabilization
DK843_RS09785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DK843_RS09790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DK843_RS09805	COG0745	RESPONSE REGULATOR receiver
DK843_RS09810	COG2205	protein histidine kinase activity
DK843_RS09820	COG3591	Belongs to the peptidase S1B family
DK843_RS09825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DK843_RS09830	COG0631	protein serine/threonine phosphatase activity
DK843_RS09835	COG1357	PFAM Pentapeptide repeats (8 copies)
DK843_RS09835	COG0515	serine threonine protein kinase
DK843_RS09840	COG1561	YicC-like family, N-terminal region
DK843_RS09855	COG0776	regulation of translation
DK843_RS09860	COG2084	Dehydrogenase
DK843_RS09865	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DK843_RS09905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DK843_RS09915	COG0438	transferase activity, transferring glycosyl groups
DK843_RS09915	COG1216	Glycosyl transferase, family 2
DK843_RS09925	COG2226	methyltransferase
DK843_RS09930	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DK843_RS09950	COG2089	acid synthase
DK843_RS09960	COG1083	cytidylyl-transferase
DK843_RS09965	COG2089	acid synthase
DK843_RS09975	COG1086	Polysaccharide biosynthesis protein
DK843_RS10000	COG3720	iron ion transport
DK843_RS10010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK843_RS10015	COG1120	ATPase activity
DK843_RS10020	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DK843_RS10025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DK843_RS10035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DK843_RS10045	COG1846	Transcriptional regulator
DK843_RS10055	COG2223	nitrite transmembrane transporter activity
DK843_RS10065	COG1678	Uncharacterized ACR, COG1678
DK843_RS10070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DK843_RS10080	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DK843_RS10085	COG3530	Putative quorum-sensing-regulated virulence factor
DK843_RS10110	COG1960	acyl-CoA dehydrogenase activity
DK843_RS10120	COG0517	IMP dehydrogenase activity
DK843_RS10120	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DK843_RS10125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DK843_RS10130	COG1309	transcriptional regulator
DK843_RS10140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DK843_RS10145	COG1538	Outer membrane efflux protein
DK843_RS10150	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DK843_RS10185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DK843_RS10225	COG0840	transmembrane signaling receptor activity
DK843_RS10225	COG3290	protein histidine kinase activity
DK843_RS10235	COG4977	sequence-specific DNA binding
DK843_RS10260	COG1111	helicase
DK843_RS10260	COG1205	dead DEAH box helicase
DK843_RS10325	COG0281	malic enzyme
DK843_RS10325	COG0280	phosphate acetyltransferase
DK843_RS10340	COG2990	Protein conserved in bacteria
DK843_RS10345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DK843_RS10355	COG3511	phospholipase C
DK843_RS10370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DK843_RS10375	COG0625	glutathione transferase activity
DK843_RS10405	COG0318	PFAM AMP-dependent synthetase and ligase
DK843_RS10410	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DK843_RS10435	COG0642	Histidine kinase
DK843_RS10440	COG0745	RESPONSE REGULATOR receiver
DK843_RS10450	COG0438	transferase activity, transferring glycosyl groups
DK843_RS10465	COG2226	methyltransferase
DK843_RS10470	COG3437	response regulator, receiver
DK843_RS10475	COG2205	protein histidine kinase activity
DK843_RS10475	COG0784	Response regulator, receiver
DK843_RS10475	COG5002	protein histidine kinase activity
DK843_RS10485	COG2172	sigma factor antagonist activity
DK843_RS10495	COG1366	Belongs to the anti-sigma-factor antagonist family
DK843_RS10500	COG0708	Exodeoxyribonuclease III
DK843_RS10510	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DK843_RS10520	COG0840	transmembrane signaling receptor activity
DK843_RS10525	COG0531	amino acid
DK843_RS10535	COG1770	oligopeptidase
DK843_RS10545	COG0848	biopolymer transport protein
DK843_RS10570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DK843_RS10600	COG1196	nuclear chromosome segregation
DK843_RS10635	COG4598	ABC transporter
DK843_RS10640	COG4160	amino acid transport
DK843_RS10655	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DK843_RS10660	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DK843_RS10665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DK843_RS10670	COG0142	geranyltranstransferase activity
DK843_RS10680	COG0582	viral genome integration into host DNA
DK843_RS10755	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DK843_RS10760	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DK843_RS10770	COG1132	(ABC) transporter
DK843_RS10785	COG0438	transferase activity, transferring glycosyl groups
DK843_RS10790	COG0859	PFAM glycosyl transferase family 9
DK843_RS10795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DK843_RS10810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DK843_RS10810	COG1648	precorrin-2 dehydrogenase activity
DK843_RS10815	COG3706	GGDEF domain
DK843_RS10825	COG1959	2 iron, 2 sulfur cluster binding
DK843_RS10825	COG1295	ribonuclease BN
DK843_RS10835	COG0110	maltose O-acetyltransferase activity
DK843_RS10845	COG2223	nitrite transmembrane transporter activity
DK843_RS10885	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DK843_RS10890	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DK843_RS10895	COG1242	4 iron, 4 sulfur cluster binding
DK843_RS10905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DK843_RS10910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DK843_RS10910	COG2813	Specifically methylates the guanine in position
DK843_RS10920	COG2814	Major facilitator Superfamily
DK843_RS10960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DK843_RS10985	COG0477	Major facilitator Superfamily
DK843_RS10990	COG1393	Belongs to the ArsC family
DK843_RS10995	COG1846	Transcriptional regulator
DK843_RS11000	COG1538	Outer membrane efflux protein
DK843_RS11010	COG2814	Major facilitator Superfamily
DK843_RS11015	COG0583	DNA-binding transcription factor activity
DK843_RS11020	COG2855	membrane
DK843_RS11050	COG1966	Carbon starvation protein
DK843_RS11055	COG0745	RESPONSE REGULATOR receiver
DK843_RS11060	COG2205	protein histidine kinase activity
DK843_RS11075	COG0408	coproporphyrinogen oxidase activity
DK843_RS11115	COG2076	Multidrug Resistance protein
DK843_RS11120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DK843_RS11125	COG0463	Glycosyl transferase, family 2
DK843_RS11135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DK843_RS11135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DK843_RS11140	COG0726	polysaccharide deacetylase
DK843_RS11145	COG3152	Membrane
DK843_RS11175	COG0583	DNA-binding transcription factor activity
DK843_RS11180	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DK843_RS11275	COG0583	DNA-binding transcription factor activity
DK843_RS11300	COG1309	transcriptional regulator
DK843_RS11315	COG2814	Major facilitator Superfamily
DK843_RS11335	COG0656	L-ascorbic acid biosynthetic process
DK843_RS11340	COG2814	Major facilitator Superfamily
DK843_RS11345	COG0583	DNA-binding transcription factor activity
DK843_RS11355	COG1028	Short-chain dehydrogenase reductase Sdr
DK843_RS11375	COG1126	abc transporter atp-binding protein
DK843_RS11380	COG0765	amino acid transport
DK843_RS11385	COG0765	amino acid transport
DK843_RS11390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK843_RS11410	COG1917	Cupin 2, conserved barrel domain protein
DK843_RS11415	COG5285	phytanoyl-CoA dioxygenase
DK843_RS11440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DK843_RS11445	COG1349	DNA-binding transcription factor activity
DK843_RS11470	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DK843_RS11475	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DK843_RS11480	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DK843_RS11485	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DK843_RS11490	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DK843_RS11495	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DK843_RS11500	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DK843_RS11510	COG0356	it plays a direct role in the translocation of protons across the membrane
DK843_RS11525	COG1192	Involved in chromosome partitioning
DK843_RS11530	COG0357	Ribosomal RNA small subunit methyltransferase G
DK843_RS11535	COG0445	tRNA wobble uridine modification
DK843_RS11545	COG1720	tRNA m6t6A37 methyltransferase activity
DK843_RS11555	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DK843_RS11560	COG2823	Periplasmic or secreted lipoprotein
DK843_RS11565	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DK843_RS11570	COG0792	nuclease activity
DK843_RS11615	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DK843_RS11640	COG3781	membrane
DK843_RS11645	COG1132	(ABC) transporter
DK843_RS11650	COG1132	(ABC) transporter
DK843_RS11655	COG0494	nUDIX hydrolase
DK843_RS11665	COG0084	hydrolase, TatD family'
DK843_RS11670	COG0840	transmembrane signaling receptor activity
DK843_RS11685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DK843_RS11690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DK843_RS11700	COG0140	phosphoribosyl-ATP diphosphatase activity
DK843_RS11705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DK843_RS11710	COG0107	imidazoleglycerol-phosphate synthase activity
DK843_RS11715	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DK843_RS11720	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DK843_RS11725	COG0131	Imidazoleglycerol-phosphate dehydratase
DK843_RS11730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DK843_RS11740	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DK843_RS11745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DK843_RS11750	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DK843_RS11755	COG1999	signal sequence binding
DK843_RS11760	COG0109	protoheme IX farnesyltransferase activity
DK843_RS11765	COG1612	heme a metabolic process
DK843_RS11795	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DK843_RS11800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DK843_RS11805	COG1565	acr, cog1565
DK843_RS11805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DK843_RS11810	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DK843_RS11830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DK843_RS11845	COG0688	phosphatidylethanolamine metabolic process
DK843_RS11855	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DK843_RS11860	COG0440	acetolactate synthase activity
DK843_RS11865	COG0028	Belongs to the TPP enzyme family
DK843_RS11905	COG0402	S-adenosylhomocysteine deaminase activity
DK843_RS11915	COG0741	lytic transglycosylase activity
DK843_RS11920	COG0442	prolyl-tRNA aminoacylation
DK843_RS11925	COG3158	transport of potassium into the cell
DK843_RS11960	COG3945	hemerythrin HHE cation binding domain
DK843_RS11975	COG0745	RESPONSE REGULATOR receiver
DK843_RS11980	COG1522	sequence-specific DNA binding
DK843_RS11985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DK843_RS11990	COG1263	PTS System
DK843_RS11990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK843_RS11990	COG2190	(PTS) system
DK843_RS11995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DK843_RS11995	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK843_RS12000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DK843_RS12005	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DK843_RS12010	COG2188	Transcriptional regulator
DK843_RS12020	COG0697	spore germination
DK843_RS12025	COG0811	peptide transport
DK843_RS12030	COG0009	L-threonylcarbamoyladenylate synthase
DK843_RS12105	COG0463	Glycosyl transferase, family 2
DK843_RS12110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DK843_RS12135	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DK843_RS12140	COG0151	Belongs to the GarS family
DK843_RS12145	COG0138	bifunctional purine biosynthesis protein purh
DK843_RS12205	COG0456	acetyltransferase
DK843_RS12210	COG3447	MASE1 domain protein
DK843_RS12210	COG5002	protein histidine kinase activity
DK843_RS12210	COG5001	Diguanylate cyclase
DK843_RS12230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DK843_RS12235	COG0508	dehydrogenase complex catalyzes the overall conversion of
DK843_RS12260	COG1584	GPR1 FUN34 yaaH family protein
DK843_RS12265	COG0288	reversible hydration of carbon dioxide
DK843_RS12270	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DK843_RS12275	COG0799	negative regulation of ribosome biogenesis
DK843_RS12280	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DK843_RS12290	COG0438	transferase activity, transferring glycosyl groups
DK843_RS12315	COG2814	Major facilitator Superfamily
DK843_RS12320	COG1466	dna polymerase III delta subunit
DK843_RS12330	COG0495	leucyl-tRNA aminoacylation
DK843_RS12340	COG0730	response to heat
DK843_RS12355	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DK843_RS12375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DK843_RS12385	COG4206	TonB-dependent receptor
DK843_RS12390	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DK843_RS12395	COG0406	alpha-ribazole phosphatase activity
DK843_RS12400	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DK843_RS12405	COG0010	Belongs to the arginase family
DK843_RS12420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DK843_RS12430	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DK843_RS12490	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DK843_RS12495	COG0514	ATP-dependent DNA helicase (RecQ)
DK843_RS12505	COG1192	Involved in chromosome partitioning
DK843_RS12510	COG2205	protein histidine kinase activity
DK843_RS12565	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DK843_RS12575	COG2124	cytochrome p450
DK843_RS12585	COG0640	Transcriptional regulator
DK843_RS12605	COG2056	Na+-H+ antiporter family
DK843_RS12610	COG2900	Belongs to the SlyX family
DK843_RS12620	COG0456	acetyltransferase
DK843_RS12630	COG0436	Aminotransferase
DK843_RS12635	COG2171	N-acyltransferase activity
DK843_RS12640	COG1127	ABC transporter
DK843_RS12645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DK843_RS12650	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DK843_RS12670	COG2824	Alkylphosphonate utilization operon protein PhnA
DK843_RS12675	COG1335	isochorismatase
DK843_RS12685	COG0583	DNA-binding transcription factor activity
DK843_RS12690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DK843_RS12700	COG0842	Transport permease protein
DK843_RS12705	COG1131	(ABC) transporter
DK843_RS12725	COG1538	Outer membrane efflux protein
DK843_RS12875	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DK843_RS12880	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DK843_RS12910	COG0840	transmembrane signaling receptor activity
DK843_RS12920	COG2226	methyltransferase
DK843_RS12925	COG1012	belongs to the aldehyde dehydrogenase family
DK843_RS12930	COG3284	Transcriptional regulator
DK843_RS12935	COG0583	DNA-binding transcription factor activity
DK843_RS12940	COG2249	NAD(P)H dehydrogenase (quinone) activity
DK843_RS12965	COG2202	Pas domain
DK843_RS12965	COG3920	Histidine kinase
DK843_RS12980	COG0513	Belongs to the DEAD box helicase family
DK843_RS12990	COG4681	YaeQ
DK843_RS13000	COG1451	nucleotide metabolic process
DK843_RS13040	COG0038	chloride channel
DK843_RS13045	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
DK843_RS13050	COG0540	Belongs to the ATCase OTCase family
DK843_RS13060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DK843_RS13075	COG3240	lipase activity
DK843_RS13080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DK843_RS13085	COG3240	lipase activity
DK843_RS13090	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DK843_RS13090	COG2199	diguanylate cyclase activity
DK843_RS13095	COG0657	acetylesterase activity
DK843_RS13130	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DK843_RS13225	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DK843_RS13240	COG1448	Aminotransferase
DK843_RS13250	COG2321	neutral zinc metallopeptidase
DK843_RS13260	COG1943	Transposase
DK843_RS13280	COG2986	histidine ammonia-lyase
DK843_RS13285	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DK843_RS13290	COG0010	Belongs to the arginase family
DK843_RS13295	COG1228	amidohydrolase
DK843_RS13300	COG2188	Transcriptional regulator
DK843_RS13310	COG0676	glucose-6-phosphate 1-epimerase activity
DK843_RS13360	COG5001	Diguanylate cyclase
DK843_RS13370	COG1538	Outer membrane efflux protein
DK843_RS13380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DK843_RS13385	COG2197	response regulator
DK843_RS13390	COG2962	Rard protein
DK843_RS13405	COG0583	DNA-binding transcription factor activity
DK843_RS13415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DK843_RS13430	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DK843_RS13450	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DK843_RS13455	COG0737	Belongs to the 5'-nucleotidase family
DK843_RS13465	COG4628	conserved protein (DUF2132)
DK843_RS13570	COG0826	peptidase U32
DK843_RS13595	COG1175	transmembrane transport
DK843_RS13600	COG0395	ABC-type sugar transport system, permease component
DK843_RS13605	COG1472	Belongs to the glycosyl hydrolase 3 family
DK843_RS13610	COG3842	ATPase activity
DK843_RS13635	COG2271	Major facilitator Superfamily
DK843_RS13640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DK843_RS13645	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DK843_RS13650	COG0469	pyruvate kinase activity
DK843_RS13670	COG3214	Protein conserved in bacteria
DK843_RS13695	COG3706	GGDEF domain
DK843_RS13700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DK843_RS13705	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DK843_RS13730	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DK843_RS13735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DK843_RS13740	COG1054	Belongs to the UPF0176 family
DK843_RS13745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DK843_RS13750	COG1253	flavin adenine dinucleotide binding
DK843_RS13775	COG0859	PFAM glycosyl transferase family 9
DK843_RS13780	COG1519	Transferase
DK843_RS13790	COG3161	chorismate lyase activity
DK843_RS13815	COG0583	DNA-binding transcription factor activity
DK843_RS13850	COG3150	esterase
DK843_RS13860	COG1846	Transcriptional regulator
DK843_RS13865	COG1764	response to oxidative stress
DK843_RS13885	COG0210	DNA helicase
DK843_RS13895	COG1410	methionine synthase
DK843_RS13895	COG0646	methionine synthase
DK843_RS13930	COG0625	glutathione transferase activity
DK843_RS13935	COG4122	O-methyltransferase activity
DK843_RS13945	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DK843_RS13950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DK843_RS13955	COG0126	phosphoglycerate kinase activity
DK843_RS13965	COG1280	lysine exporter protein (LysE YggA)
DK843_RS13975	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DK843_RS13980	COG0314	molybdopterin synthase activity
DK843_RS14000	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DK843_RS14015	COG0745	RESPONSE REGULATOR receiver
DK843_RS14015	COG2972	Histidine kinase
DK843_RS14050	COG0823	Involved in the tonB-independent uptake of proteins
DK843_RS14085	COG2200	EAL domain
DK843_RS14090	COG0165	Argininosuccinate lyase
DK843_RS14100	COG1126	abc transporter atp-binding protein
DK843_RS14105	COG0765	amino acid transport
DK843_RS14110	COG0765	amino acid transport
DK843_RS14120	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DK843_RS14130	COG0424	maF-like protein
DK843_RS14135	COG1530	ribonuclease E activity
DK843_RS14150	COG0006	proline dipeptidase activity
DK843_RS14155	COG3135	benzoate transporter
DK843_RS14165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DK843_RS14175	COG0579	oxidoreductase
DK843_RS14185	COG2199	diguanylate cyclase activity
DK843_RS14185	COG2200	EAL domain
DK843_RS14185	COG2203	Gaf domain
DK843_RS14200	COG2814	Major facilitator Superfamily
DK843_RS14205	COG0583	DNA-binding transcription factor activity
DK843_RS14210	COG0800	Aldolase
DK843_RS14220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DK843_RS14230	COG0837	glucose binding
DK843_RS14235	COG0837	glucose binding
DK843_RS14235	COG1737	Transcriptional regulator
DK843_RS14240	COG0166	Belongs to the GPI family
DK843_RS14250	COG0352	thiamine-phosphate diphosphorylase activity
DK843_RS14255	COG0351	phosphomethylpyrimidine kinase
DK843_RS14265	COG4783	chaperone-mediated protein folding
DK843_RS14275	COG1981	membrane
DK843_RS14280	COG2954	triphosphatase activity
DK843_RS14310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DK843_RS14320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DK843_RS14325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DK843_RS14340	COG0288	reversible hydration of carbon dioxide
DK843_RS14345	COG0446	pyridine nucleotide-disulphide oxidoreductase
DK843_RS14345	COG1902	pentaerythritol trinitrate reductase activity
DK843_RS14360	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DK843_RS14375	COG0762	integral membrane protein
DK843_RS14405	COG0745	RESPONSE REGULATOR receiver
DK843_RS14425	COG0318	PFAM AMP-dependent synthetase and ligase
DK843_RS14430	COG1309	transcriptional regulator
DK843_RS14440	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
DK843_RS14460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DK843_RS14475	COG0640	Transcriptional regulator
DK843_RS14490	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DK843_RS14495	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DK843_RS14500	COG4206	TonB-dependent receptor
DK843_RS14550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DK843_RS14575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DK843_RS14600	COG0583	DNA-binding transcription factor activity
DK843_RS14610	COG0259	pyridoxamine-phosphate oxidase activity
DK843_RS14625	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DK843_RS14630	COG0181	hydroxymethylbilane synthase activity
DK843_RS14645	COG2959	enzyme of heme biosynthesis
DK843_RS14655	COG0583	DNA-binding transcription factor activity
DK843_RS14660	COG0477	Major facilitator Superfamily
DK843_RS14670	COG5001	Diguanylate cyclase
DK843_RS14670	COG3706	GGDEF domain
DK843_RS14670	COG2203	Gaf domain
DK843_RS14670	COG4251	negative regulation of phosphorylation
DK843_RS14680	COG1045	serine acetyltransferase
DK843_RS14700	COG1965	Belongs to the frataxin family
DK843_RS14710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DK843_RS14720	COG5654	RES domain protein
DK843_RS14725	COG5642	Protein of unknown function (DUF2384)
DK843_RS14735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DK843_RS14750	COG0840	transmembrane signaling receptor activity
DK843_RS14760	COG0583	DNA-binding transcription factor activity
DK843_RS14765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DK843_RS14850	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DK843_RS14880	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DK843_RS14885	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DK843_RS14890	COG0594	ribonuclease P activity
DK843_RS14895	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DK843_RS14900	COG0706	membrane insertase activity
DK843_RS14905	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DK843_RS14920	COG1174	glycine betaine transport
DK843_RS14925	COG1125	glycine betaine transport
DK843_RS14930	COG1174	glycine betaine transport
DK843_RS14935	COG1732	Glycine betaine
DK843_RS14940	COG2827	Endonuclease containing a URI domain
DK843_RS14950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DK843_RS14955	COG1333	cytochrome c biogenesis protein
DK843_RS14965	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DK843_RS14985	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DK843_RS14990	COG0156	8-amino-7-oxononanoate synthase activity
DK843_RS15000	COG2226	methyltransferase
DK843_RS15005	COG2267	carboxylic ester hydrolase activity
DK843_RS15010	COG2226	methyltransferase
DK843_RS15020	COG1752	Esterase of the alpha-beta hydrolase superfamily
DK843_RS15025	COG0625	glutathione transferase activity
DK843_RS15050	COG0733	neurotransmitter:sodium symporter activity
DK843_RS15060	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DK843_RS15085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DK843_RS15090	COG0612	Peptidase, M16
DK843_RS15095	COG0772	Belongs to the SEDS family
DK843_RS15100	COG0768	penicillin binding
DK843_RS15105	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DK843_RS15110	COG1792	Involved in formation and maintenance of cell shape
DK843_RS15115	COG1077	Cell shape determining protein MreB Mrl
DK843_RS15120	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DK843_RS15125	COG0154	amidase activity
DK843_RS15130	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DK843_RS15135	COG2001	Belongs to the MraZ family
DK843_RS15140	COG0275	rRNA processing
DK843_RS15145	COG3116	cell division
DK843_RS15155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DK843_RS15160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DK843_RS15165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DK843_RS15170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DK843_RS15175	COG0772	Belongs to the SEDS family
DK843_RS15180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DK843_RS15185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DK843_RS15190	COG1181	Belongs to the D-alanine--D-alanine ligase family
DK843_RS15195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DK843_RS15210	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DK843_RS15220	COG0315	cyclic pyranopterin monophosphate synthase activity
DK843_RS15240	COG0425	Belongs to the sulfur carrier protein TusA family
DK843_RS15245	COG0418	dihydroorotase activity
DK843_RS15255	COG0601	transmembrane transport
DK843_RS15260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DK843_RS15270	COG4608	Belongs to the ABC transporter superfamily
DK843_RS15285	COG0393	Putative heavy-metal-binding
DK843_RS15315	COG2134	cdp-diacylglycerol pyrophosphatase
DK843_RS15320	COG0346	lactoylglutathione lyase activity
DK843_RS15325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DK843_RS15360	COG1505	serine-type exopeptidase activity
DK843_RS15365	COG3590	peptidase
DK843_RS15395	COG3132	Protein of unknown function, DUF480
DK843_RS15400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DK843_RS15405	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DK843_RS15410	COG0589	response to stress
DK843_RS15420	COG0174	glutamine synthetase
DK843_RS15425	COG0840	transmembrane signaling receptor activity
DK843_RS15450	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DK843_RS15475	COG1116	anion transmembrane transporter activity
DK843_RS15485	COG3540	Alkaline phosphatase
DK843_RS15490	COG0653	protein targeting
DK843_RS15500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DK843_RS15505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DK843_RS15515	COG0189	ligase activity
DK843_RS15540	COG2922	Belongs to the Smg family
DK843_RS15555	COG0242	peptide deformylase activity
DK843_RS15560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DK843_RS15565	COG0501	Belongs to the peptidase M48B family
DK843_RS15580	COG5000	phosphorelay sensor kinase activity
DK843_RS15585	COG2204	response regulator
DK843_RS15590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DK843_RS15595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DK843_RS15600	COG0824	Thioesterase
DK843_RS15615	COG0783	Belongs to the Dps family
DK843_RS15620	COG1872	DUF167
DK843_RS15630	COG1324	tolerance protein
DK843_RS15680	COG2832	Protein of unknown function (DUF454)
DK843_RS15695	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DK843_RS15700	COG0708	Exodeoxyribonuclease III
DK843_RS15715	COG0840	transmembrane signaling receptor activity
DK843_RS15725	COG1253	flavin adenine dinucleotide binding
DK843_RS15745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DK843_RS15755	COG0789	Transcriptional regulator
DK843_RS15760	COG0247	lactate metabolic process
DK843_RS15765	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DK843_RS15770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DK843_RS15775	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DK843_RS15790	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DK843_RS15795	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DK843_RS15810	COG0632	four-way junction helicase activity
DK843_RS15825	COG2204	response regulator
DK843_RS15835	COG2205	protein histidine kinase activity
DK843_RS15840	COG0307	riboflavin synthase, alpha
DK843_RS15845	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DK843_RS15850	COG2255	four-way junction helicase activity
DK843_RS15865	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DK843_RS15870	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DK843_RS15880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DK843_RS15910	COG2884	Cell division ATP-binding protein ftsE
DK843_RS15920	COG0742	ribosomal rna small subunit methyltransferase
DK843_RS15925	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DK843_RS15945	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DK843_RS15955	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DK843_RS15965	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DK843_RS15970	COG0081	regulation of translation
DK843_RS15980	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DK843_RS15985	COG0222	ribosome binding
DK843_RS15990	COG0085	RNA polymerase activity
DK843_RS15995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DK843_RS16000	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DK843_RS16005	COG0049	tRNA binding
DK843_RS16010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DK843_RS16015	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DK843_RS16020	COG0051	transcription antitermination factor activity, RNA binding
DK843_RS16025	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DK843_RS16030	COG0088	Forms part of the polypeptide exit tunnel
DK843_RS16035	COG0089	rRNA binding
DK843_RS16040	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DK843_RS16045	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DK843_RS16050	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DK843_RS16055	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DK843_RS16060	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DK843_RS16065	COG0255	Belongs to the universal ribosomal protein uL29 family
DK843_RS16070	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DK843_RS16075	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DK843_RS16080	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DK843_RS16085	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DK843_RS16090	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DK843_RS16095	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DK843_RS16100	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DK843_RS16105	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DK843_RS16110	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DK843_RS16115	COG1841	ribosomal large subunit assembly
DK843_RS16120	COG0200	Binds to the 23S rRNA
DK843_RS16125	COG0201	protein transport
DK843_RS16130	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DK843_RS16135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DK843_RS16140	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DK843_RS16145	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DK843_RS16150	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DK843_RS16155	COG0202	RNA polymerase activity
DK843_RS16160	COG0203	ribosomal protein L17
DK843_RS16165	COG2066	Belongs to the glutaminase family
DK843_RS16170	COG3217	Mosc domain protein beta barrel domain protein
DK843_RS16170	COG0633	Ferredoxin
DK843_RS16180	COG0840	transmembrane signaling receptor activity
DK843_RS16185	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DK843_RS16190	COG4535	Mg2 and Co2 transporter CorC
DK843_RS16195	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DK843_RS16200	COG1702	phosphate starvation-inducible protein PhoH
DK843_RS16215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DK843_RS16225	COG4651	solute:proton antiporter activity
DK843_RS16225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DK843_RS16245	COG0583	DNA-binding transcription factor activity
DK843_RS16250	COG1024	Enoyl-CoA hydratase
DK843_RS16250	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DK843_RS16255	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DK843_RS16260	COG1960	acyl-CoA dehydrogenase activity
DK843_RS16265	COG1216	Glycosyl transferase, family 2
DK843_RS16285	COG1028	Short-chain dehydrogenase reductase Sdr
DK843_RS16290	COG0037	tRNA processing
DK843_RS16295	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DK843_RS16370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DK843_RS16375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DK843_RS16400	COG0583	DNA-binding transcription factor activity
DK843_RS16405	COG1027	Aspartate ammonia-lyase
DK843_RS16425	COG3171	Protein conserved in bacteria
DK843_RS16455	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DK843_RS16460	COG3047	cAMP biosynthetic process
DK843_RS16465	COG3842	ATPase activity
DK843_RS16475	COG1177	transmembrane transport
DK843_RS16480	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DK843_RS16545	COG1012	belongs to the aldehyde dehydrogenase family
DK843_RS16555	COG2197	response regulator
DK843_RS16560	COG0583	DNA-binding transcription factor activity
DK843_RS16570	COG3154	lipid carrier protein
DK843_RS16580	COG0826	peptidase U32
DK843_RS16610	COG3094	Invasion gene expression up-regulator, SirB
DK843_RS16615	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DK843_RS16620	COG1074	ATP-dependent DNA helicase activity
DK843_RS16635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DK843_RS16650	COG1132	(ABC) transporter
DK843_RS16655	COG1051	belongs to the nudix hydrolase family
DK843_RS16670	COG0210	DNA helicase
DK843_RS16675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DK843_RS16700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DK843_RS16710	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DK843_RS16715	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DK843_RS16725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DK843_RS16730	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DK843_RS16735	COG0193	aminoacyl-tRNA hydrolase activity
DK843_RS16740	COG0012	GTP binding
DK843_RS16750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK843_RS16755	COG0765	amino acid transport
DK843_RS16760	COG1022	Amp-dependent synthetase and ligase
DK843_RS16805	COG3706	GGDEF domain
DK843_RS16815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DK843_RS16820	COG0069	glutamate synthase activity
DK843_RS16820	COG0070	glutamate synthase
DK843_RS16820	COG0067	glutamate synthase
DK843_RS16825	COG0493	'glutamate synthase
DK843_RS16835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DK843_RS16840	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DK843_RS16845	COG1088	dTDP-glucose 4,6-dehydratase activity
DK843_RS16850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DK843_RS16870	COG2089	acid synthase
DK843_RS16880	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DK843_RS16885	COG1083	cytidylyl-transferase
DK843_RS16890	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DK843_RS16895	COG1028	Short-chain dehydrogenase reductase Sdr
DK843_RS16920	COG0438	transferase activity, transferring glycosyl groups
DK843_RS16930	COG0110	maltose O-acetyltransferase activity
DK843_RS16940	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DK843_RS16955	COG0463	Glycosyl transferase, family 2
DK843_RS16970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DK843_RS16980	COG0459	protein refolding
DK843_RS16995	COG1091	dTDP-4-dehydrorhamnose reductase activity
DK843_RS17005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DK843_RS17010	COG0723	plastoquinol--plastocyanin reductase activity
DK843_RS17015	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DK843_RS17020	COG2857	Cytochrome c1
DK843_RS17025	COG0625	glutathione transferase activity
DK843_RS17030	COG2969	positive regulation of protein catabolic process
DK843_RS17035	COG0004	ammonium transporteR
DK843_RS17040	COG0347	Belongs to the P(II) protein family
DK843_RS17070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DK843_RS17090	COG0109	protoheme IX farnesyltransferase activity
DK843_RS17245	COG0367	asparagine synthase
DK843_RS17255	COG0647	UMP catabolic process
DK843_RS17270	COG0142	geranyltranstransferase activity
DK843_RS17280	COG2226	methyltransferase
DK843_RS17290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DK843_RS17295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DK843_RS17300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DK843_RS17305	COG1028	Short-chain dehydrogenase reductase Sdr
DK843_RS17310	COG0446	pyridine nucleotide-disulphide oxidoreductase
DK843_RS17310	COG1902	pentaerythritol trinitrate reductase activity
DK843_RS17315	COG1063	alcohol dehydrogenase
DK843_RS17325	COG0577	efflux transmembrane transporter activity
DK843_RS17325	COG1136	(ABC) transporter
DK843_RS17445	COG0784	Response regulator, receiver
DK843_RS17445	COG5002	protein histidine kinase activity
DK843_RS17445	COG2205	protein histidine kinase activity
DK843_RS17450	COG2197	response regulator
DK843_RS17475	COG2207	Transcriptional regulator
DK843_RS17530	COG0747	negative chemotaxis
DK843_RS17575	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DK843_RS17580	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DK843_RS17585	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DK843_RS17590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DK843_RS17620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DK843_RS17625	COG0306	phosphate transporter
DK843_RS17630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DK843_RS17635	COG0581	inorganic phosphate transmembrane transporter activity
DK843_RS17650	COG0149	triose-phosphate isomerase activity
DK843_RS17655	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DK843_RS17665	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DK843_RS17670	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DK843_RS17675	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DK843_RS17680	COG0649	NAD binding
DK843_RS17695	COG1034	ATP synthesis coupled electron transport
DK843_RS17700	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DK843_RS17705	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DK843_RS17715	COG0713	ATP synthesis coupled electron transport
DK843_RS17730	COG1007	ATP synthesis coupled electron transport
DK843_RS17745	COG2226	methyltransferase
DK843_RS17750	COG1560	Kdo2-lipid A biosynthetic process
DK843_RS17760	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DK843_RS17765	COG3706	GGDEF domain
DK843_RS17770	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DK843_RS17775	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DK843_RS17785	COG1522	sequence-specific DNA binding
DK843_RS17795	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DK843_RS17805	COG0625	glutathione transferase activity
DK843_RS17835	COG0561	phosphatase activity
DK843_RS17840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DK843_RS17850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DK843_RS17850	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK843_RS17860	COG0583	DNA-binding transcription factor activity
DK843_RS17875	COG2264	protein methyltransferase activity
DK843_RS17880	COG0439	Biotin carboxylase
DK843_RS17885	COG0511	ligase activity, forming carbon-carbon bonds
DK843_RS17890	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DK843_RS17895	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DK843_RS17905	COG2226	methyltransferase
DK843_RS17915	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DK843_RS17920	COG1252	NADH dehydrogenase
DK843_RS17935	COG0436	Aminotransferase
DK843_RS17975	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DK843_RS17980	COG0513	Belongs to the DEAD box helicase family
DK843_RS18000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DK843_RS18005	COG2200	EAL domain
DK843_RS18005	COG2199	diguanylate cyclase activity
DK843_RS18005	COG2202	Pas domain
DK843_RS18010	COG2201	protein-glutamate methylesterase activity
DK843_RS18015	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DK843_RS18020	COG0840	transmembrane signaling receptor activity
DK843_RS18025	COG0835	chemotaxis
DK843_RS18030	COG0840	transmembrane signaling receptor activity
DK843_RS18035	COG2198	Histidine kinase
DK843_RS18035	COG0643	Histidine kinase
DK843_RS18045	COG0745	RESPONSE REGULATOR receiver
DK843_RS18055	COG0527	aspartate kinase activity
DK843_RS18095	COG0322	excinuclease ABC activity
DK843_RS18105	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DK843_RS18125	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DK843_RS18135	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DK843_RS18150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DK843_RS18155	COG0402	S-adenosylhomocysteine deaminase activity
DK843_RS18175	COG4650	regulator
DK843_RS18185	COG1690	Belongs to the RtcB family
DK843_RS18190	COG3541	Predicted nucleotidyltransferase
DK843_RS18210	COG3469	chitinase activity
DK843_RS18215	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DK843_RS18220	COG1690	Belongs to the RtcB family
DK843_RS18315	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DK843_RS18325	COG0039	L-malate dehydrogenase activity
DK843_RS18330	COG2188	Transcriptional regulator
DK843_RS18335	COG2009	succinate dehydrogenase
DK843_RS18345	COG1053	succinate dehydrogenase
DK843_RS18350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DK843_RS18355	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DK843_RS18365	COG0567	Dehydrogenase, E1 component
DK843_RS18370	COG0508	dehydrogenase complex catalyzes the overall conversion of
DK843_RS18380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DK843_RS18390	COG0045	succinate-CoA ligase (ADP-forming) activity
DK843_RS18420	COG0572	uridine kinase
DK843_RS18435	COG0633	Ferredoxin
DK843_RS18440	COG0443	Heat shock 70 kDa protein
DK843_RS18445	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DK843_RS18455	COG0822	iron-sulfur transferase activity
DK843_RS18460	COG1104	cysteine desulfurase activity
DK843_RS18475	COG0747	negative chemotaxis
DK843_RS18480	COG0601	transmembrane transport
DK843_RS18485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DK843_RS18490	COG0444	Belongs to the ABC transporter superfamily
DK843_RS18495	COG4608	Belongs to the ABC transporter superfamily
DK843_RS18505	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DK843_RS18515	COG0786	glutamate:sodium symporter activity
DK843_RS18520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DK843_RS18555	COG3852	Histidine kinase
DK843_RS18560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DK843_RS18565	COG0494	nUDIX hydrolase
DK843_RS18605	COG0114	fumarate hydratase activity
DK843_RS18610	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DK843_RS18615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DK843_RS18630	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DK843_RS18640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DK843_RS18650	COG0302	gtp cyclohydrolase
DK843_RS18655	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DK843_RS18660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DK843_RS18665	COG0583	DNA-binding transcription factor activity
DK843_RS18675	COG0697	spore germination
DK843_RS18685	COG1012	belongs to the aldehyde dehydrogenase family
DK843_RS18685	COG1454	alcohol dehydrogenase
DK843_RS18690	COG1113	amino acid transport
DK843_RS18700	COG0667	Aldo Keto reductase
DK843_RS18730	COG0740	serine-type endopeptidase activity
DK843_RS18740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DK843_RS18745	COG5001	Diguanylate cyclase
DK843_RS18745	COG3300	MHYT domain
DK843_RS18750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DK843_RS18765	COG0583	DNA-binding transcription factor activity
DK843_RS18775	COG1346	cytolysis
DK843_RS18780	COG0789	Transcriptional regulator
DK843_RS18795	COG1607	acyl-coa hydrolase
DK843_RS18805	COG0564	pseudouridine synthase activity
DK843_RS18820	COG0463	Glycosyl transferase, family 2
DK843_RS18825	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DK843_RS18830	COG3104	oligopeptide transport
DK843_RS18840	COG3033	Beta-eliminating lyase
DK843_RS18850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DK843_RS18860	COG4533	DNA binding
DK843_RS18880	COG2010	Cytochrome c
DK843_RS18895	COG3278	Belongs to the heme-copper respiratory oxidase family
DK843_RS18905	COG0308	aminopeptidase N
DK843_RS18910	COG0071	Belongs to the small heat shock protein (HSP20) family
DK843_RS18920	COG2814	Major facilitator Superfamily
DK843_RS18930	COG0251	oxidation-reduction process
DK843_RS18940	COG4302	ethanolamine ammonia-lyase activity
DK843_RS18950	COG0531	amino acid
DK843_RS18955	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DK843_RS18965	COG3437	response regulator, receiver
DK843_RS18970	COG0784	Response regulator, receiver
DK843_RS18970	COG2205	protein histidine kinase activity
DK843_RS18970	COG5002	protein histidine kinase activity
DK843_RS19005	COG3604	Transcriptional regulator
DK843_RS19010	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DK843_RS19020	COG3260	NADH ubiquinone oxidoreductase 20
DK843_RS19025	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DK843_RS19030	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
DK843_RS19030	COG3261	NADH dehydrogenase
DK843_RS19035	COG0651	ATP synthesis coupled electron transport
DK843_RS19040	COG4237	Hydrogenase 4 membrane
DK843_RS19045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DK843_RS19050	COG0650	Formate hydrogenlyase subunit 4
DK843_RS19055	COG0651	ATP synthesis coupled electron transport
DK843_RS19060	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DK843_RS19080	COG0409	Hydrogenase expression formation protein
DK843_RS19090	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DK843_RS19100	COG0375	protein maturation
DK843_RS19105	COG0493	'glutamate synthase
DK843_RS19105	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DK843_RS19110	COG3383	formate dehydrogenase (NAD+) activity
DK843_RS19115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DK843_RS19150	COG1301	dicarboxylic acid transport
DK843_RS19170	COG0489	protein tyrosine kinase activity
DK843_RS19180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK843_RS19180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK843_RS19200	COG3596	GTP binding
DK843_RS19215	COG1028	Short-chain dehydrogenase reductase Sdr
DK843_RS19225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK843_RS19245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DK843_RS19250	COG2192	nodulation
DK843_RS19260	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DK843_RS19265	COG0534	Mate efflux family protein
DK843_RS19280	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DK843_RS19290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DK843_RS19295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DK843_RS19315	COG3022	response to hydroperoxide
DK843_RS19320	COG1490	D-aminoacyl-tRNA deacylase activity
DK843_RS19325	COG1289	transmembrane transporter activity
DK843_RS19330	COG0741	lytic transglycosylase activity
DK843_RS19330	COG1388	LysM domain
DK843_RS19335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DK843_RS19340	COG2226	methyltransferase
DK843_RS19345	COG0328	RNA-DNA hybrid ribonuclease activity
DK843_RS19350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DK843_RS19355	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DK843_RS19360	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DK843_RS19365	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DK843_RS19370	COG0704	Plays a role in the regulation of phosphate uptake
DK843_RS19375	COG0248	Ppx GppA phosphatase
DK843_RS19380	COG0598	Magnesium transport protein CorA
DK843_RS19400	COG1335	isochorismatase
DK843_RS19405	COG2217	Heavy metal translocating P-type atpase
DK843_RS19410	COG2608	mercury ion transmembrane transporter activity
DK843_RS19430	COG0765	amino acid transport
DK843_RS19435	COG0765	amino acid transport
DK843_RS19440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK843_RS19450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DK843_RS19455	COG4589	Belongs to the CDS family
DK843_RS19465	COG2267	carboxylic ester hydrolase activity
DK843_RS19470	COG0671	phosphoesterase, PA-phosphatase related
DK843_RS19470	COG2453	phosphatase
DK843_RS19485	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DK843_RS19490	COG0129	dihydroxy-acid dehydratase activity
DK843_RS19500	COG2076	Multidrug Resistance protein
DK843_RS19505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DK843_RS19515	COG0583	DNA-binding transcription factor activity
DK843_RS19520	COG1741	Belongs to the pirin family
DK843_RS19525	COG1335	isochorismatase
DK843_RS19535	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DK843_RS19540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DK843_RS19545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DK843_RS19555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DK843_RS19560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DK843_RS19560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DK843_RS19570	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DK843_RS19590	COG3121	Chaperone
DK843_RS19595	COG3188	usher protein
DK843_RS19640	COG0322	excinuclease ABC activity
DK843_RS19645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DK843_RS19680	COG3023	N-Acetylmuramoyl-L-alanine amidase
DK843_RS19720	COG0326	Molecular chaperone. Has ATPase activity
DK843_RS19730	COG1335	isochorismatase
DK843_RS19770	COG1968	undecaprenyl-diphosphatase activity
DK843_RS19795	COG3842	ATPase activity
DK843_RS19800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DK843_RS19825	COG0586	Pfam SNARE associated Golgi protein
DK843_RS19830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DK843_RS19835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DK843_RS19840	COG1862	Preprotein translocase
DK843_RS19845	COG0343	queuine tRNA-ribosyltransferase activity
DK843_RS19855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DK843_RS19860	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DK843_RS19865	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DK843_RS19870	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DK843_RS19875	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DK843_RS19880	COG0072	phenylalanine-tRNA ligase activity
DK843_RS19880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK843_RS19885	COG0776	regulation of translation
DK843_RS19915	COG2119	membrane
DK843_RS19920	COG1970	mechanosensitive ion channel activity
DK843_RS19960	COG2866	Carboxypeptidase
DK843_RS19975	COG2226	methyltransferase
DK843_RS19985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DK843_RS19990	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DK843_RS19995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DK843_RS20010	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DK843_RS20015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DK843_RS20020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DK843_RS20040	COG0745	RESPONSE REGULATOR receiver
DK843_RS20070	COG1857	crispr-associated protein
DK843_RS20085	COG1518	maintenance of DNA repeat elements
DK843_RS20090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DK843_RS20095	COG0583	DNA-binding transcription factor activity
DK843_RS20105	COG1280	lysine exporter protein (LysE YggA)
DK843_RS20125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DK843_RS20135	COG0494	nUDIX hydrolase
DK843_RS20140	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DK843_RS20155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DK843_RS20175	COG0673	inositol 2-dehydrogenase activity
DK843_RS20180	COG1760	l-serine dehydratase
DK843_RS20185	COG0814	amino acid
DK843_RS20190	COG2116	formate transmembrane transporter activity
DK843_RS20200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DK843_RS20205	COG3142	Participates in the control of copper homeostasis
DK843_RS20235	COG2972	Histidine kinase
DK843_RS20245	COG0488	(ABC) transporter
DK843_RS20250	COG5342	invasion associated locus B
DK843_RS20410	COG0174	glutamine synthetase
DK843_RS20415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DK843_RS20435	COG2095	MarC family integral membrane protein
DK843_RS20440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DK843_RS20445	COG1393	Belongs to the ArsC family
DK843_RS20455	COG0318	PFAM AMP-dependent synthetase and ligase
DK843_RS20460	COG0779	Required for maturation of 30S ribosomal subunits
DK843_RS20465	COG2251	uridine kinase activity
DK843_RS20465	COG0195	Participates in both transcription termination and antitermination
DK843_RS20470	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DK843_RS20475	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DK843_RS20480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DK843_RS20485	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DK843_RS20490	COG1185	polyribonucleotide nucleotidyltransferase activity
DK843_RS20505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DK843_RS20510	COG1028	Short-chain dehydrogenase reductase Sdr
DK843_RS20515	COG1535	isochorismatase
DK843_RS20515	COG3433	isochorismatase activity
DK843_RS20520	COG1021	2,3-dihydroxybenzoate-AMP ligase
DK843_RS20525	COG1169	isochorismate synthase
DK843_RS20530	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DK843_RS20530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DK843_RS20540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK843_RS20555	COG4771	TonB-dependent receptor
DK843_RS20570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DK843_RS20585	COG1012	belongs to the aldehyde dehydrogenase family
DK843_RS20590	COG3724	N-succinylarginine dihydrolase activity
DK843_RS20595	COG0559	Belongs to the binding-protein-dependent transport system permease family
DK843_RS20615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK843_RS20625	COG2814	Major facilitator Superfamily
DK843_RS20655	COG1643	Atp-dependent helicase
DK843_RS20670	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DK843_RS20680	COG4585	Histidine kinase
DK843_RS20685	COG4585	Histidine kinase
DK843_RS20690	COG2197	response regulator
DK843_RS20700	COG1349	DNA-binding transcription factor activity
DK843_RS20715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DK843_RS20735	COG0697	spore germination
DK843_RS20780	COG4191	Histidine kinase
DK843_RS20790	COG4160	amino acid transport
DK843_RS20805	COG2902	Dehydrogenase
DK843_RS20815	COG3706	GGDEF domain
DK843_RS20820	COG0756	dUTP diphosphatase activity
DK843_RS20825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DK843_RS20830	COG2003	Belongs to the UPF0758 family
DK843_RS20860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DK843_RS20865	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DK843_RS20875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DK843_RS20875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DK843_RS20915	COG0243	molybdopterin cofactor binding
DK843_RS20925	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DK843_RS20940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DK843_RS20945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DK843_RS20965	COG0583	DNA-binding transcription factor activity
DK843_RS20970	COG0617	tRNA 3'-terminal CCA addition
DK843_RS20975	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DK843_RS20985	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DK843_RS20990	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DK843_RS20995	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DK843_RS21010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DK843_RS21020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DK843_RS21025	COG0443	Heat shock 70 kDa protein
DK843_RS21030	COG3239	Fatty acid desaturase
DK843_RS21035	COG0484	heat shock protein binding
DK843_RS21060	COG1063	alcohol dehydrogenase
DK843_RS21065	COG0840	transmembrane signaling receptor activity
DK843_RS21070	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DK843_RS21075	COG0752	glycyl-tRNA synthetase alpha subunit
DK843_RS21090	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DK843_RS21115	COG1966	Carbon starvation protein
DK843_RS21125	COG3279	Response regulator of the LytR AlgR family
DK843_RS21130	COG3275	phosphorelay sensor kinase activity
DK843_RS21135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DK843_RS21145	COG0733	neurotransmitter:sodium symporter activity
DK843_RS21185	COG0840	transmembrane signaling receptor activity
DK843_RS21190	COG3842	ATPase activity
DK843_RS21210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DK843_RS21215	COG0446	pyridine nucleotide-disulphide oxidoreductase
DK843_RS21225	COG0252	asparaginase activity
DK843_RS21235	COG1566	PFAM secretion protein HlyD family protein
DK843_RS21260	COG0613	PHP domain protein
DK843_RS21265	COG0009	L-threonylcarbamoyladenylate synthase
DK843_RS21275	COG1994	Peptidase M50
DK843_RS21280	COG0180	Tryptophanyl-tRNA synthetase
DK843_RS21300	COG1558	bacterial-type flagellum-dependent cell motility
DK843_RS21320	COG4786	Flagellar basal body rod
DK843_RS21325	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DK843_RS21330	COG1706	bacterial-type flagellum-dependent cell motility
DK843_RS21340	COG1256	bacterial-type flagellum assembly
DK843_RS21355	COG0367	asparagine synthase
DK843_RS21360	COG1522	sequence-specific DNA binding
DK843_RS21400	COG0659	secondary active sulfate transmembrane transporter activity
DK843_RS21410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DK843_RS21445	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DK843_RS21460	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DK843_RS21465	COG1032	radical SAM domain protein
DK843_RS21480	COG2226	methyltransferase
DK843_RS21485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DK843_RS21490	COG0737	Belongs to the 5'-nucleotidase family
DK843_RS21495	COG0205	6-phosphofructokinase activity
DK843_RS21500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DK843_RS21500	COG2755	lipolytic protein G-D-S-L family
DK843_RS21505	COG0215	cysteine-tRNA ligase activity
DK843_RS21510	COG0254	rRNA binding
DK843_RS21540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DK843_RS21560	COG4770	biotin carboxylase activity
DK843_RS21565	COG1024	Enoyl-CoA hydratase
DK843_RS21570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DK843_RS21580	COG1960	acyl-CoA dehydrogenase activity
DK843_RS21590	COG1671	Belongs to the UPF0178 family
DK843_RS21600	COG2223	nitrite transmembrane transporter activity
DK843_RS21605	COG3279	Response regulator of the LytR AlgR family
DK843_RS21610	COG3275	phosphorelay sensor kinase activity
DK843_RS21625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DK843_RS21625	COG1017	nitric oxide dioxygenase activity
DK843_RS21630	COG0625	glutathione transferase activity
DK843_RS21635	COG1846	Transcriptional regulator
DK843_RS21640	COG0697	spore germination
DK843_RS21645	COG0456	acetyltransferase
DK843_RS21650	COG0789	Transcriptional regulator
DK843_RS21655	COG0318	PFAM AMP-dependent synthetase and ligase
DK843_RS21660	COG3012	SEC-C Motif Domain Protein
DK843_RS21660	COG3318	Belongs to the UPF0149 family
DK843_RS21680	COG1960	acyl-CoA dehydrogenase activity
DK843_RS21690	COG0494	nUDIX hydrolase
DK843_RS21700	COG2766	serine protein kinase
DK843_RS21705	COG2718	Belongs to the UPF0229 family
DK843_RS21710	COG2719	SpoVR family
DK843_RS21725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK843_RS21730	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DK843_RS21735	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DK843_RS21745	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DK843_RS21750	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DK843_RS21760	COG0167	dihydroorotate dehydrogenase activity
DK843_RS21775	COG0616	signal peptide processing
DK843_RS21775	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DK843_RS21785	COG0546	phosphoglycolate phosphatase activity
DK843_RS21800	COG1530	ribonuclease E activity
DK843_RS21815	COG0671	phosphoesterase, PA-phosphatase related
DK843_RS21820	COG0477	Major facilitator Superfamily
DK843_RS21825	COG3681	Belongs to the UPF0597 family
DK843_RS21830	COG3437	response regulator, receiver
DK843_RS21835	COG0784	Response regulator, receiver
DK843_RS21835	COG2205	protein histidine kinase activity
DK843_RS21835	COG5002	protein histidine kinase activity
DK843_RS21845	COG4771	TonB-dependent receptor
DK843_RS21850	COG2207	Transcriptional regulator
DK843_RS21860	COG0583	DNA-binding transcription factor activity
DK843_RS21865	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DK843_RS21870	COG4208	sulfate ABC transporter
DK843_RS21875	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DK843_RS21880	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DK843_RS21910	COG3454	Phosphonate metabolism
DK843_RS21915	COG4778	phosphonate C-P lyase system protein PhnL
DK843_RS21920	COG4107	phosphonate C-P lyase system protein PhnK
DK843_RS21925	COG3627	carbon phosphorus lyase activity
DK843_RS21930	COG3626	phosphonate metabolism
DK843_RS21935	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
DK843_RS21940	COG3624	Phosphonate C-P lyase system protein PhnG
DK843_RS21945	COG2188	Transcriptional regulator
DK843_RS21950	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DK843_RS21955	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DK843_RS21985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK843_RS21985	COG2205	protein histidine kinase activity
DK843_RS21995	COG1840	ABC-type Fe3 transport system, periplasmic component
DK843_RS22000	COG3842	ATPase activity
DK843_RS22030	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
DK843_RS22040	COG0583	DNA-binding transcription factor activity
DK843_RS22045	COG0583	DNA-binding transcription factor activity
DK843_RS22050	COG1473	amidohydrolase
DK843_RS22070	COG3938	Belongs to the proline racemase family
DK843_RS22075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DK843_RS22085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DK843_RS22120	COG2814	Major facilitator Superfamily
DK843_RS22150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DK843_RS22155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DK843_RS22205	COG3842	ATPase activity
DK843_RS22210	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DK843_RS22225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DK843_RS22230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DK843_RS22250	COG0784	Response regulator, receiver
DK843_RS22250	COG2198	Histidine kinase
DK843_RS22250	COG5002	protein histidine kinase activity
DK843_RS22260	COG0583	DNA-binding transcription factor activity
DK843_RS22265	COG1802	Transcriptional regulator
DK843_RS22295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DK843_RS22300	COG0788	formyltetrahydrofolate deformylase activity
DK843_RS22325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DK843_RS22330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DK843_RS22335	COG1376	ErfK ybiS ycfS ynhG family protein
DK843_RS22345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DK843_RS22355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DK843_RS22360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DK843_RS22370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DK843_RS22375	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DK843_RS22385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DK843_RS22385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DK843_RS22395	COG0542	response to heat
DK843_RS22400	COG2818	Glycosylase
DK843_RS22405	COG2207	Transcriptional regulator
DK843_RS22405	COG4753	response regulator
DK843_RS22415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK843_RS22415	COG2205	protein histidine kinase activity
DK843_RS22420	COG2833	Protein of unknown function (DUF455)
DK843_RS22435	COG0826	peptidase U32
DK843_RS22445	COG1176	ABC-type spermidine putrescine transport system, permease component I
DK843_RS22450	COG1177	transmembrane transport
DK843_RS22460	COG0018	arginyl-trna synthetase
DK843_RS22730	COG2161	toxin-antitoxin pair type II binding
DK843_RS22735	COG4115	mRNA cleavage