locus-tag	class	description
BKX93_RS00120	COG0747	negative chemotaxis
BKX93_RS00165	COG3590	peptidase
BKX93_RS00170	COG2356	endonuclease I
BKX93_RS00185	COG1199	ATP-dependent helicase activity
BKX93_RS00195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKX93_RS00200	COG0137	argininosuccinate synthase activity
BKX93_RS00230	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BKX93_RS00235	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BKX93_RS00255	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKX93_RS00285	COG2860	membrane
BKX93_RS00300	COG0583	DNA-binding transcription factor activity
BKX93_RS00305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKX93_RS00325	COG1012	belongs to the aldehyde dehydrogenase family
BKX93_RS00335	COG1917	Cupin 2, conserved barrel domain protein
BKX93_RS00335	COG1396	sequence-specific DNA binding
BKX93_RS00340	COG0686	Belongs to the AlaDH PNT family
BKX93_RS00345	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BKX93_RS00350	COG0174	glutamine synthetase
BKX93_RS00365	COG1360	Flagellar Motor Protein
BKX93_RS00380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKX93_RS00390	COG0617	tRNA 3'-terminal CCA addition
BKX93_RS00400	COG0739	heme binding
BKX93_RS00400	COG0741	lytic transglycosylase activity
BKX93_RS00400	COG1196	nuclear chromosome segregation
BKX93_RS00405	COG0346	lactoylglutathione lyase activity
BKX93_RS00410	COG0678	peroxiredoxin activity
BKX93_RS00410	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BKX93_RS00415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKX93_RS00425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BKX93_RS00435	COG2217	Heavy metal translocating P-type atpase
BKX93_RS00440	COG3321	synthase
BKX93_RS00440	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS00440	COG0604	alcohol dehydrogenase
BKX93_RS00465	COG0347	Belongs to the P(II) protein family
BKX93_RS00470	COG1280	lysine exporter protein (LysE YggA)
BKX93_RS00475	COG1666	GTP binding
BKX93_RS00480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKX93_RS00495	COG1063	alcohol dehydrogenase
BKX93_RS00505	COG2828	Protein conserved in bacteria
BKX93_RS00545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKX93_RS00555	COG0481	GTPase activity
BKX93_RS00570	COG0571	ribonuclease III activity
BKX93_RS00575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BKX93_RS00585	COG1381	Involved in DNA repair and RecF pathway recombination
BKX93_RS00590	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BKX93_RS00600	COG0736	holo-[acyl-carrier-protein] synthase activity
BKX93_RS00605	COG1472	Belongs to the glycosyl hydrolase 3 family
BKX93_RS00635	COG1162	GTPase activity
BKX93_RS00650	COG1024	Enoyl-CoA hydratase
BKX93_RS00655	COG1024	Enoyl-CoA hydratase
BKX93_RS00660	COG1960	acyl-CoA dehydrogenase activity
BKX93_RS00670	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKX93_RS00695	COG1309	transcriptional regulator
BKX93_RS00700	COG0859	PFAM glycosyl transferase family 9
BKX93_RS00715	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BKX93_RS00730	COG0312	modulator of DNA gyrase
BKX93_RS00755	COG1473	amidohydrolase
BKX93_RS00765	COG0529	Catalyzes the synthesis of activated sulfate
BKX93_RS00805	COG0066	3-isopropylmalate dehydratase activity
BKX93_RS00810	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKX93_RS00815	COG0583	DNA-binding transcription factor activity
BKX93_RS00830	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BKX93_RS00840	COG0512	Glutamine amidotransferase of anthranilate synthase
BKX93_RS00845	COG1733	regulation of RNA biosynthetic process
BKX93_RS00860	COG0546	phosphoglycolate phosphatase activity
BKX93_RS00865	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS00870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BKX93_RS00875	COG2967	ApaG domain
BKX93_RS00880	COG5265	(ABC) transporter
BKX93_RS00905	COG1418	mRNA catabolic process
BKX93_RS00945	COG0052	Belongs to the universal ribosomal protein uS2 family
BKX93_RS00950	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BKX93_RS00955	COG0528	UMP kinase activity
BKX93_RS00960	COG0233	cytoplasmic translational termination
BKX93_RS00965	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BKX93_RS00970	COG0575	Belongs to the CDS family
BKX93_RS00975	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BKX93_RS00990	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BKX93_RS00995	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKX93_RS01000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKX93_RS01005	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKX93_RS01010	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKX93_RS01015	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKX93_RS01040	COG2204	response regulator
BKX93_RS01050	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BKX93_RS01065	COG1858	cytochrome C peroxidase
BKX93_RS01095	COG1115	amino acid carrier protein
BKX93_RS01100	COG3707	response regulator
BKX93_RS01105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKX93_RS01110	COG2223	nitrite transmembrane transporter activity
BKX93_RS01115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKX93_RS01125	COG0243	molybdopterin cofactor binding
BKX93_RS01140	COG2382	esterase
BKX93_RS01150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKX93_RS01150	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BKX93_RS01155	COG1120	ATPase activity
BKX93_RS01160	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKX93_RS01165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKX93_RS01175	COG4592	Periplasmic binding protein
BKX93_RS01185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKX93_RS01195	COG0346	lactoylglutathione lyase activity
BKX93_RS01220	COG0738	Major facilitator superfamily
BKX93_RS01240	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BKX93_RS01305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKX93_RS01335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKX93_RS01340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKX93_RS01345	COG3568	Endonuclease Exonuclease Phosphatase
BKX93_RS01350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKX93_RS01355	COG2011	ABC-type metal ion transport system permease component
BKX93_RS01380	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BKX93_RS01395	COG1619	proteins homologs of microcin C7 resistance protein MccF
BKX93_RS01405	COG0175	sulfate reduction
BKX93_RS01410	COG2895	sulfate adenylyltransferase (ATP) activity
BKX93_RS01420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKX93_RS01420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKX93_RS01420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKX93_RS01425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKX93_RS01430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKX93_RS01430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKX93_RS01430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKX93_RS01440	COG2207	Transcriptional regulator
BKX93_RS01450	COG0582	viral genome integration into host DNA
BKX93_RS01515	COG2974	May be involved in recombination
BKX93_RS01835	COG2135	peptidase activity
BKX93_RS01845	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKX93_RS01850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKX93_RS01875	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BKX93_RS01955	COG4386	tail sheath protein
BKX93_RS02015	COG4381	Mu-like prophage protein gp46
BKX93_RS02020	COG3299	homolog of phage Mu protein gp47
BKX93_RS02035	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BKX93_RS02075	COG4974	Belongs to the 'phage' integrase family
BKX93_RS02095	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BKX93_RS02125	COG0497	DNA recombination
BKX93_RS02130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKX93_RS02135	COG4566	intracellular signal transduction
BKX93_RS02145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKX93_RS02150	COG0123	including yeast histone deacetylase and acetoin utilization protein
BKX93_RS02160	COG1247	-acetyltransferase
BKX93_RS02170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKX93_RS02180	COG1294	oxidase, subunit
BKX93_RS02185	COG1271	oxidase subunit
BKX93_RS02200	COG3220	belongs to the UPF0276 family
BKX93_RS02220	COG0024	Methionine aminopeptidase
BKX93_RS02225	COG2378	regulation of single-species biofilm formation
BKX93_RS02235	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BKX93_RS02235	COG0237	dephospho-CoA kinase activity
BKX93_RS02245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKX93_RS02255	COG1942	4-Oxalocrotonate Tautomerase
BKX93_RS02265	COG1435	thymidine kinase activity
BKX93_RS02280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BKX93_RS02285	COG0564	pseudouridine synthase activity
BKX93_RS02290	COG1744	ABC transporter substrate-binding protein PnrA-like
BKX93_RS02295	COG3845	ABC transporter
BKX93_RS02300	COG4603	Belongs to the binding-protein-dependent transport system permease family
BKX93_RS02305	COG1079	Belongs to the binding-protein-dependent transport system permease family
BKX93_RS02310	COG0303	'Molybdopterin
BKX93_RS02320	COG0628	permease
BKX93_RS02355	COG1573	uracil-dna glycosylase
BKX93_RS02360	COG2070	2-Nitropropane dioxygenase
BKX93_RS02370	COG0545	Peptidyl-prolyl cis-trans isomerase
BKX93_RS02375	COG1956	GAF domain-containing protein
BKX93_RS02380	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS02390	COG2154	pterin-4-alpha-carbinolamine dehydratase
BKX93_RS02400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BKX93_RS02405	COG0166	Belongs to the GPI family
BKX93_RS02420	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BKX93_RS02425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKX93_RS02455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKX93_RS02460	COG0733	neurotransmitter:sodium symporter activity
BKX93_RS02490	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BKX93_RS02495	COG1629	transport
BKX93_RS02500	COG0307	riboflavin synthase, alpha
BKX93_RS02515	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BKX93_RS02520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKX93_RS02530	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BKX93_RS02540	COG0443	Heat shock 70 kDa protein
BKX93_RS02545	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BKX93_RS02550	COG0024	Methionine aminopeptidase
BKX93_RS02565	COG0745	RESPONSE REGULATOR receiver
BKX93_RS02580	COG1187	pseudouridine synthase activity
BKX93_RS02605	COG1217	gtp-binding protein TYPA
BKX93_RS02625	COG2814	Major facilitator Superfamily
BKX93_RS02630	COG0625	glutathione transferase activity
BKX93_RS02640	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BKX93_RS02650	COG0038	chloride channel
BKX93_RS02655	COG0583	DNA-binding transcription factor activity
BKX93_RS02685	COG1744	ABC transporter substrate-binding protein PnrA-like
BKX93_RS02690	COG2375	cellular response to nickel ion
BKX93_RS02695	COG1695	Transcriptional regulator
BKX93_RS02700	COG0840	transmembrane signaling receptor activity
BKX93_RS02710	COG1988	membrane-bound metal-dependent
BKX93_RS02715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKX93_RS02720	COG1131	(ABC) transporter
BKX93_RS02725	COG0842	Transport permease protein
BKX93_RS02730	COG0842	Transport permease protein
BKX93_RS02740	COG0534	Mate efflux family protein
BKX93_RS02780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKX93_RS02785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKX93_RS02950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKX93_RS02955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKX93_RS02960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKX93_RS02965	COG1024	Enoyl-CoA hydratase
BKX93_RS02970	COG1024	Enoyl-CoA hydratase
BKX93_RS02975	COG3425	synthase
BKX93_RS02985	COG3321	synthase
BKX93_RS02985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKX93_RS02985	COG4221	oxidoreductase activity
BKX93_RS02985	COG0300	oxidoreductase activity
BKX93_RS02990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKX93_RS02990	COG3321	synthase
BKX93_RS02990	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS02990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKX93_RS02990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKX93_RS02995	COG3321	synthase
BKX93_RS02995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKX93_RS02995	COG4221	oxidoreductase activity
BKX93_RS02995	COG0300	oxidoreductase activity
BKX93_RS03025	COG0318	PFAM AMP-dependent synthetase and ligase
BKX93_RS03025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKX93_RS03025	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS03025	COG3321	synthase
BKX93_RS03025	COG0300	oxidoreductase activity
BKX93_RS03030	COG4221	oxidoreductase activity
BKX93_RS03030	COG3321	synthase
BKX93_RS03030	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS03030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKX93_RS03040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKX93_RS03045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKX93_RS03055	COG2207	Transcriptional regulator
BKX93_RS03070	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKX93_RS03085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BKX93_RS03095	COG0739	heme binding
BKX93_RS03100	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BKX93_RS03105	COG1674	ftsk spoiiie
BKX93_RS03110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BKX93_RS03130	COG1024	Enoyl-CoA hydratase
BKX93_RS03180	COG0789	Transcriptional regulator
BKX93_RS03200	COG0753	catalase activity
BKX93_RS03250	COG2823	Periplasmic or secreted lipoprotein
BKX93_RS03270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKX93_RS03300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKX93_RS03325	COG3411	Ferredoxin
BKX93_RS03335	COG2081	HI0933 family
BKX93_RS03340	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BKX93_RS03345	COG2203	Gaf domain
BKX93_RS03345	COG3706	GGDEF domain
BKX93_RS03345	COG4251	negative regulation of phosphorylation
BKX93_RS03345	COG5001	Diguanylate cyclase
BKX93_RS03350	COG2201	protein-glutamate methylesterase activity
BKX93_RS03355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BKX93_RS03370	COG0643	Histidine kinase
BKX93_RS03370	COG2198	Histidine kinase
BKX93_RS03385	COG0840	transmembrane signaling receptor activity
BKX93_RS03400	COG1286	toxin biosynthetic process
BKX93_RS03410	COG0285	dihydrofolate synthase activity
BKX93_RS03425	COG0488	(ABC) transporter
BKX93_RS03440	COG0791	NLP P60 protein
BKX93_RS03465	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BKX93_RS03480	COG0697	spore germination
BKX93_RS03485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKX93_RS03490	COG1763	Mo-molybdopterin cofactor biosynthetic process
BKX93_RS03495	COG3850	Histidine kinase
BKX93_RS03500	COG2197	response regulator
BKX93_RS03515	COG2801	Transposase and inactivated derivatives
BKX93_RS03530	COG2181	nitrate reductase activity
BKX93_RS03535	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BKX93_RS03540	COG1140	nitrate reductase beta subunit
BKX93_RS03545	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BKX93_RS03550	COG2223	nitrite transmembrane transporter activity
BKX93_RS03565	COG3008	intermembrane lipid transfer
BKX93_RS03570	COG2995	paraquat-inducible protein a
BKX93_RS03590	COG0583	DNA-binding transcription factor activity
BKX93_RS03595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKX93_RS03615	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BKX93_RS03620	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKX93_RS03625	COG0740	serine-type endopeptidase activity
BKX93_RS03630	COG0544	peptidyl-prolyl cis-trans isomerase activity
BKX93_RS03640	COG0537	adenosine 5'-monophosphoramidase activity
BKX93_RS03645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKX93_RS03660	COG4221	oxidoreductase activity
BKX93_RS03665	COG0583	DNA-binding transcription factor activity
BKX93_RS03675	COG5001	Diguanylate cyclase
BKX93_RS03685	COG0295	cytidine deaminase activity
BKX93_RS03695	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BKX93_RS03700	COG5001	Diguanylate cyclase
BKX93_RS03720	COG5002	protein histidine kinase activity
BKX93_RS03720	COG0784	Response regulator, receiver
BKX93_RS03720	COG2205	protein histidine kinase activity
BKX93_RS03725	COG0745	RESPONSE REGULATOR receiver
BKX93_RS03735	COG0840	transmembrane signaling receptor activity
BKX93_RS03740	COG3048	D-serine ammonia-lyase activity
BKX93_RS03745	COG0583	DNA-binding transcription factor activity
BKX93_RS03760	COG2977	Belongs to the P-Pant transferase superfamily
BKX93_RS03770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKX93_RS03785	COG2124	cytochrome p450
BKX93_RS03825	COG0156	8-amino-7-oxononanoate synthase activity
BKX93_RS03835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKX93_RS03845	COG0387	Pfam Sodium calcium exchanger
BKX93_RS03850	COG0596	Alpha beta hydrolase
BKX93_RS03855	COG1959	2 iron, 2 sulfur cluster binding
BKX93_RS03860	COG0384	phenazine biosynthesis protein PhzF
BKX93_RS03870	COG0525	valine-tRNA ligase activity
BKX93_RS03875	COG0525	valine-tRNA ligase activity
BKX93_RS03900	COG2194	sulfuric ester hydrolase activity
BKX93_RS03920	COG0457	Tetratricopeptide repeat
BKX93_RS03925	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BKX93_RS03930	COG1215	transferase activity, transferring glycosyl groups
BKX93_RS03935	COG1215	transferase activity, transferring glycosyl groups
BKX93_RS03955	COG0583	DNA-binding transcription factor activity
BKX93_RS03975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKX93_RS03990	COG0300	oxidoreductase activity
BKX93_RS03995	COG1722	exodeoxyribonuclease VII activity
BKX93_RS04000	COG0142	geranyltranstransferase activity
BKX93_RS04005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BKX93_RS04020	COG2195	Cleaves the N-terminal amino acid of tripeptides
BKX93_RS04055	COG0577	efflux transmembrane transporter activity
BKX93_RS04055	COG1136	(ABC) transporter
BKX93_RS04060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKX93_RS04065	COG0583	DNA-binding transcription factor activity
BKX93_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS04100	COG0134	indole-3-glycerol-phosphate synthase activity
BKX93_RS04105	COG5380	lipid catabolic process
BKX93_RS04110	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BKX93_RS04115	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKX93_RS04135	COG0183	Belongs to the thiolase family
BKX93_RS04140	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKX93_RS04140	COG1024	Enoyl-CoA hydratase
BKX93_RS04155	COG1960	acyl-CoA dehydrogenase activity
BKX93_RS04180	COG1454	alcohol dehydrogenase
BKX93_RS04185	COG2095	MarC family integral membrane protein
BKX93_RS04190	COG0833	amino acid
BKX93_RS04195	COG3158	transport of potassium into the cell
BKX93_RS04200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKX93_RS04205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKX93_RS04220	COG3858	chitin binding
BKX93_RS04220	COG1388	LysM domain
BKX93_RS04235	COG0625	glutathione transferase activity
BKX93_RS04245	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BKX93_RS04250	COG2226	methyltransferase
BKX93_RS04295	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKX93_RS04300	COG1765	OsmC-like protein
BKX93_RS04305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BKX93_RS04310	COG0488	(ABC) transporter
BKX93_RS04320	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BKX93_RS04325	COG0159	tryptophan synthase activity
BKX93_RS04330	COG0133	tryptophan synthase activity
BKX93_RS04340	COG0101	tRNA pseudouridine synthase activity
BKX93_RS04355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BKX93_RS04375	COG0473	3-isopropylmalate dehydrogenase activity
BKX93_RS04395	COG0066	3-isopropylmalate dehydratase activity
BKX93_RS04405	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKX93_RS04420	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BKX93_RS04425	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKX93_RS04430	COG3243	poly(R)-hydroxyalkanoic acid synthase
BKX93_RS04435	COG0183	Belongs to the thiolase family
BKX93_RS04460	COG0789	Transcriptional regulator
BKX93_RS04465	COG0655	NAD(P)H dehydrogenase (quinone) activity
BKX93_RS04480	COG0006	proline dipeptidase activity
BKX93_RS04500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKX93_RS04510	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS04525	COG0492	ferredoxin-NADP+ reductase activity
BKX93_RS04535	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BKX93_RS04540	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BKX93_RS04560	COG0488	(ABC) transporter
BKX93_RS04580	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BKX93_RS04600	COG0084	hydrolase, TatD family'
BKX93_RS04615	COG1280	lysine exporter protein (LysE YggA)
BKX93_RS04620	COG1902	pentaerythritol trinitrate reductase activity
BKX93_RS04625	COG0656	L-ascorbic acid biosynthetic process
BKX93_RS04630	COG2814	Major facilitator Superfamily
BKX93_RS04635	COG0583	DNA-binding transcription factor activity
BKX93_RS04640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKX93_RS04645	COG0513	Belongs to the DEAD box helicase family
BKX93_RS04650	COG3655	Transcriptional regulator
BKX93_RS04660	COG4178	(ABC) transporter
BKX93_RS04690	COG1566	PFAM secretion protein HlyD family protein
BKX93_RS04700	COG1073	alpha beta
BKX93_RS04705	COG0727	PFAM Uncharacterised protein family (UPF0153)
BKX93_RS04745	COG1473	amidohydrolase
BKX93_RS04880	COG0616	signal peptide processing
BKX93_RS04895	COG4626	Terminase
BKX93_RS04895	COG1802	Transcriptional regulator
BKX93_RS04920	COG1484	DNA-dependent DNA replication
BKX93_RS04965	COG0840	transmembrane signaling receptor activity
BKX93_RS04970	COG0513	Belongs to the DEAD box helicase family
BKX93_RS04975	COG2175	clavaminate synthase activity
BKX93_RS04980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKX93_RS04985	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BKX93_RS04990	COG4521	taurine ABC transporter
BKX93_RS05000	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BKX93_RS05010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKX93_RS05015	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BKX93_RS05045	COG2831	hemolysin activation secretion protein
BKX93_RS05050	COG1760	l-serine dehydratase
BKX93_RS05055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKX93_RS05060	COG1166	arginine decarboxylase activity
BKX93_RS05065	COG2988	succinylglutamate desuccinylase activity
BKX93_RS05070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKX93_RS05085	COG1706	bacterial-type flagellum-dependent cell motility
BKX93_RS05090	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BKX93_RS05105	COG1749	Flagellar hook protein flgE
BKX93_RS05115	COG1558	bacterial-type flagellum-dependent cell motility
BKX93_RS05120	COG1815	bacterial-type flagellum-dependent cell motility
BKX93_RS05135	COG2771	luxR family
BKX93_RS05135	COG2200	EAL domain
BKX93_RS05140	COG0513	Belongs to the DEAD box helicase family
BKX93_RS05155	COG1940	carbohydrate kinase activity
BKX93_RS05175	COG0395	ABC-type sugar transport system, permease component
BKX93_RS05190	COG0477	Major facilitator Superfamily
BKX93_RS05205	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BKX93_RS05210	COG2816	NAD+ diphosphatase activity
BKX93_RS05225	COG2801	Transposase and inactivated derivatives
BKX93_RS05270	COG0840	transmembrane signaling receptor activity
BKX93_RS05275	COG2096	Adenosyltransferase
BKX93_RS05290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BKX93_RS05305	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BKX93_RS05325	COG0516	GMP reductase activity
BKX93_RS05335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKX93_RS05345	COG1739	Uncharacterized protein family UPF0029
BKX93_RS05360	COG2917	probably involved in intracellular septation
BKX93_RS05365	COG2350	Protein conserved in bacteria
BKX93_RS05375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKX93_RS05380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKX93_RS05385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKX93_RS05410	COG0583	DNA-binding transcription factor activity
BKX93_RS05415	COG0121	glutamine amidotransferase
BKX93_RS05475	COG1609	Transcriptional regulator
BKX93_RS05480	COG3265	gluconokinase activity
BKX93_RS05485	COG2271	Major facilitator Superfamily
BKX93_RS05500	COG4566	intracellular signal transduction
BKX93_RS05505	COG3264	Mechanosensitive ion channel
BKX93_RS05505	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BKX93_RS05510	COG1136	(ABC) transporter
BKX93_RS05525	COG0791	NLP P60 protein
BKX93_RS05530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BKX93_RS05540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKX93_RS05560	COG1595	DNA-templated transcription, initiation
BKX93_RS05575	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS05580	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BKX93_RS05590	COG1562	ergosterol biosynthetic process
BKX93_RS05605	COG2203	Gaf domain
BKX93_RS05605	COG5001	Diguanylate cyclase
BKX93_RS05605	COG4251	negative regulation of phosphorylation
BKX93_RS05605	COG3706	GGDEF domain
BKX93_RS05610	COG1126	abc transporter atp-binding protein
BKX93_RS05615	COG0765	amino acid transport
BKX93_RS05620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKX93_RS05665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKX93_RS05670	COG1360	Flagellar Motor Protein
BKX93_RS05675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BKX93_RS05680	COG1191	sigma factor activity
BKX93_RS05735	COG1677	Flagellar hook-basal body complex protein FliE
BKX93_RS05755	COG1987	bacterial-type flagellum assembly
BKX93_RS05780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKX93_RS05780	COG2205	protein histidine kinase activity
BKX93_RS05790	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKX93_RS05810	COG1879	ABC-type sugar transport system periplasmic component
BKX93_RS05815	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKX93_RS05820	COG1129	ABC transporter
BKX93_RS05825	COG1869	D-ribose catabolic process
BKX93_RS05830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKX93_RS05840	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BKX93_RS05850	COG0625	glutathione transferase activity
BKX93_RS05860	COG1620	l-lactate permease
BKX93_RS05865	COG0277	FAD linked oxidase domain protein
BKX93_RS05870	COG1139	Iron-sulfur cluster binding protein
BKX93_RS05880	COG0247	lactate metabolic process
BKX93_RS05885	COG0835	chemotaxis
BKX93_RS05885	COG0784	Response regulator, receiver
BKX93_RS05895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKX93_RS05905	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BKX93_RS05905	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BKX93_RS05915	COG0284	orotidine-5'-phosphate decarboxylase activity
BKX93_RS05920	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BKX93_RS05930	COG0776	regulation of translation
BKX93_RS05940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BKX93_RS05945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BKX93_RS05955	COG3038	cytochrome b561
BKX93_RS05960	COG1609	Transcriptional regulator
BKX93_RS05965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKX93_RS05965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKX93_RS05970	COG1105	Belongs to the carbohydrate kinase PfkB family
BKX93_RS05975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKX93_RS05975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKX93_RS05980	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BKX93_RS06010	COG0583	DNA-binding transcription factor activity
BKX93_RS06015	COG1024	Enoyl-CoA hydratase
BKX93_RS06030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKX93_RS06045	COG0523	cobalamin synthesis protein
BKX93_RS06050	COG0735	belongs to the Fur family
BKX93_RS06080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKX93_RS06095	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BKX93_RS06100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKX93_RS06130	COG2003	Belongs to the UPF0758 family
BKX93_RS06135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BKX93_RS06140	COG0756	dUTP diphosphatase activity
BKX93_RS06155	COG2902	Dehydrogenase
BKX93_RS06165	COG4215	(ABC) transporter
BKX93_RS06170	COG4160	amino acid transport
BKX93_RS06180	COG4191	Histidine kinase
BKX93_RS06215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKX93_RS06220	COG1686	Belongs to the peptidase S11 family
BKX93_RS06225	COG2921	Belongs to the UPF0250 family
BKX93_RS06230	COG0321	lipoyl(octanoyl) transferase activity
BKX93_RS06235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BKX93_RS06260	COG0028	Belongs to the TPP enzyme family
BKX93_RS06265	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
BKX93_RS06270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BKX93_RS06295	COG0501	Belongs to the peptidase M48B family
BKX93_RS06300	COG0583	DNA-binding transcription factor activity
BKX93_RS06350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKX93_RS06355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKX93_RS06360	COG0006	proline dipeptidase activity
BKX93_RS06365	COG0217	transcriptional regulatory protein
BKX93_RS06395	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKX93_RS06430	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKX93_RS06435	COG1766	The M ring may be actively involved in energy transduction
BKX93_RS06440	COG1677	Flagellar hook-basal body complex protein FliE
BKX93_RS06450	COG2201	protein-glutamate methylesterase activity
BKX93_RS06455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKX93_RS06470	COG0583	DNA-binding transcription factor activity
BKX93_RS06490	COG2204	response regulator
BKX93_RS06510	COG0556	nucleotide-excision repair
BKX93_RS06515	COG1686	Belongs to the peptidase S11 family
BKX93_RS06530	COG1881	PFAM PEBP family protein
BKX93_RS06550	COG3842	ATPase activity
BKX93_RS06605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BKX93_RS06610	COG1984	allophanate hydrolase subunit 2
BKX93_RS06615	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BKX93_RS06630	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BKX93_RS06635	COG3186	Phenylalanine-4-hydroxylase
BKX93_RS06650	COG2067	long-chain fatty acid transport protein
BKX93_RS06665	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKX93_RS06680	COG0037	tRNA processing
BKX93_RS06685	COG0825	malonyl-CoA metabolic process
BKX93_RS06755	COG3706	GGDEF domain
BKX93_RS06760	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BKX93_RS06780	COG0312	modulator of DNA gyrase
BKX93_RS06785	COG3028	Belongs to the UPF0307 family
BKX93_RS06790	COG0521	Mo-molybdopterin cofactor biosynthetic process
BKX93_RS06795	COG0429	hydrolase of the alpha beta-hydrolase fold
BKX93_RS06815	COG0412	Dienelactone hydrolase
BKX93_RS06825	COG1278	Cold shock
BKX93_RS06855	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKX93_RS06860	COG3002	Belongs to the UPF0753 family
BKX93_RS06865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKX93_RS06870	COG0583	DNA-binding transcription factor activity
BKX93_RS06875	COG1309	transcriptional regulator
BKX93_RS06880	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BKX93_RS06890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKX93_RS06900	COG0300	oxidoreductase activity
BKX93_RS06910	COG3046	protein related to deoxyribodipyrimidine photolyase
BKX93_RS06915	COG3040	lipid binding
BKX93_RS06935	COG0459	protein refolding
BKX93_RS06950	COG1280	lysine exporter protein (LysE YggA)
BKX93_RS06960	COG1073	alpha beta
BKX93_RS06985	COG2239	Acts as a magnesium transporter
BKX93_RS06990	COG2423	ornithine cyclodeaminase activity
BKX93_RS07005	COG3706	GGDEF domain
BKX93_RS07020	COG3291	Pkd domain containing protein
BKX93_RS07035	COG2957	Belongs to the agmatine deiminase family
BKX93_RS07040	COG3920	Histidine kinase
BKX93_RS07100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKX93_RS07105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKX93_RS07110	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BKX93_RS07115	COG1231	oxidoreductase activity
BKX93_RS07125	COG2353	YceI-like domain
BKX93_RS07130	COG2353	YceI-like domain
BKX93_RS07135	COG3038	cytochrome b561
BKX93_RS07145	COG3162	membrane
BKX93_RS07150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKX93_RS07155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKX93_RS07180	COG1942	4-Oxalocrotonate Tautomerase
BKX93_RS07190	COG0583	DNA-binding transcription factor activity
BKX93_RS07195	COG2878	Part of a membrane complex involved in electron transport
BKX93_RS07200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BKX93_RS07205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKX93_RS07215	COG0531	amino acid
BKX93_RS07225	COG4580	involved in the transport of maltose and maltodextrins
BKX93_RS07230	COG0366	Alpha amylase catalytic
BKX93_RS07235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKX93_RS07235	COG1263	PTS System
BKX93_RS07245	COG2188	Transcriptional regulator
BKX93_RS07255	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BKX93_RS07265	COG0625	glutathione transferase activity
BKX93_RS07290	COG2841	Protein conserved in bacteria
BKX93_RS07295	COG0330	HflC and HflK could
BKX93_RS07300	COG0330	HflC and HflK could
BKX93_RS07310	COG0861	Integral membrane protein TerC family
BKX93_RS07325	COG4533	DNA binding
BKX93_RS07335	COG0840	transmembrane signaling receptor activity
BKX93_RS07340	COG0840	transmembrane signaling receptor activity
BKX93_RS07370	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BKX93_RS07380	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BKX93_RS07385	COG1137	ATPase activity
BKX93_RS07390	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BKX93_RS07395	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BKX93_RS07405	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BKX93_RS07410	COG1660	Displays ATPase and GTPase activities
BKX93_RS07415	COG0163	prenyltransferase activity
BKX93_RS07420	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BKX93_RS07420	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BKX93_RS07430	COG4191	Histidine kinase
BKX93_RS07430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKX93_RS07435	COG0784	Response regulator, receiver
BKX93_RS07435	COG3437	response regulator, receiver
BKX93_RS07440	COG1272	protein, Hemolysin III
BKX93_RS07445	COG0563	adenylate kinase activity
BKX93_RS07450	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BKX93_RS07455	COG2835	tetraacyldisaccharide 4'-kinase activity
BKX93_RS07460	COG1663	tetraacyldisaccharide 4'-kinase activity
BKX93_RS07465	COG0848	biopolymer transport protein
BKX93_RS07470	COG0811	peptide transport
BKX93_RS07485	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BKX93_RS07495	COG0793	Belongs to the peptidase S41A family
BKX93_RS07500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BKX93_RS07500	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BKX93_RS07505	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BKX93_RS07525	COG0488	(ABC) transporter
BKX93_RS07535	COG4942	peptidase
BKX93_RS07545	COG0861	Integral membrane protein TerC family
BKX93_RS07575	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BKX93_RS07580	COG1053	succinate dehydrogenase
BKX93_RS07585	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BKX93_RS07590	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BKX93_RS07595	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BKX93_RS07610	COG0850	regulation of cytokinetic process
BKX93_RS07620	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BKX93_RS07625	COG0583	DNA-binding transcription factor activity
BKX93_RS07670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BKX93_RS07680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BKX93_RS07705	COG0251	oxidation-reduction process
BKX93_RS07710	COG0626	cystathionine gamma-synthase activity
BKX93_RS07715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKX93_RS07720	COG4106	trans-aconitate 2-methyltransferase activity
BKX93_RS07755	COG0482	sulfurtransferase activity
BKX93_RS07760	COG2814	Major facilitator Superfamily
BKX93_RS07765	COG0583	DNA-binding transcription factor activity
BKX93_RS07770	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS07775	COG0287	Prephenate dehydrogenase
BKX93_RS07795	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BKX93_RS07800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKX93_RS07805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKX93_RS07820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKX93_RS07825	COG0416	fatty acid biosynthetic process
BKX93_RS07830	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BKX93_RS07835	COG1399	metal-binding, possibly nucleic acid-binding protein
BKX93_RS07840	COG0424	maF-like protein
BKX93_RS07850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BKX93_RS07875	COG0747	negative chemotaxis
BKX93_RS07880	COG5001	Diguanylate cyclase
BKX93_RS07880	COG3300	MHYT domain
BKX93_RS07890	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKX93_RS07890	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKX93_RS07895	COG0509	glycine decarboxylation via glycine cleavage system
BKX93_RS07900	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BKX93_RS07905	COG0531	amino acid
BKX93_RS07910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKX93_RS07920	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BKX93_RS07925	COG2201	protein-glutamate methylesterase activity
BKX93_RS07930	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BKX93_RS07935	COG0840	transmembrane signaling receptor activity
BKX93_RS07940	COG0835	chemotaxis
BKX93_RS07945	COG2198	Histidine kinase
BKX93_RS07945	COG0643	Histidine kinase
BKX93_RS07965	COG0835	chemotaxis
BKX93_RS07965	COG0784	Response regulator, receiver
BKX93_RS07970	COG0835	chemotaxis
BKX93_RS07970	COG0784	Response regulator, receiver
BKX93_RS07975	COG0745	RESPONSE REGULATOR receiver
BKX93_RS07980	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BKX93_RS07985	COG0784	Response regulator, receiver
BKX93_RS07985	COG0643	Histidine kinase
BKX93_RS07985	COG2198	Histidine kinase
BKX93_RS07990	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BKX93_RS07995	COG1214	PFAM Peptidase M22, glycoprotease
BKX93_RS08000	COG0456	acetyltransferase
BKX93_RS08005	COG1573	uracil-dna glycosylase
BKX93_RS08010	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BKX93_RS08015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BKX93_RS08020	COG0504	CTP synthase activity
BKX93_RS08025	COG0148	phosphopyruvate hydratase activity
BKX93_RS08030	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BKX93_RS08040	COG2914	Belongs to the UPF0125 (RnfH) family
BKX93_RS08045	COG2867	negative regulation of translational initiation
BKX93_RS08050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BKX93_RS08060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKX93_RS08060	COG0519	Catalyzes the synthesis of GMP from XMP
BKX93_RS08080	COG0477	Major facilitator Superfamily
BKX93_RS08115	COG0590	tRNA wobble adenosine to inosine editing
BKX93_RS08120	COG1376	ErfK ybiS ycfS ynhG family protein
BKX93_RS08160	COG0415	Belongs to the DNA photolyase family
BKX93_RS08180	COG1742	UPF0060 membrane protein
BKX93_RS08195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKX93_RS08195	COG1017	nitric oxide dioxygenase activity
BKX93_RS08200	COG3397	chitin binding
BKX93_RS08245	COG1309	transcriptional regulator
BKX93_RS08250	COG0778	Nitroreductase
BKX93_RS08255	COG1902	pentaerythritol trinitrate reductase activity
BKX93_RS08260	COG1309	transcriptional regulator
BKX93_RS08270	COG1505	serine-type exopeptidase activity
BKX93_RS08290	COG4104	PAAR repeat-containing protein
BKX93_RS08295	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BKX93_RS08300	COG0720	synthase
BKX93_RS08305	COG0602	queuosine metabolic process
BKX93_RS08320	COG3220	belongs to the UPF0276 family
BKX93_RS08335	COG0560	Phosphoserine phosphatase
BKX93_RS08345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKX93_RS08355	COG4689	acetoacetate decarboxylase
BKX93_RS08365	COG0673	inositol 2-dehydrogenase activity
BKX93_RS08395	COG0557	exoribonuclease II activity
BKX93_RS08420	COG0642	Histidine kinase
BKX93_RS08430	COG1840	ABC-type Fe3 transport system, periplasmic component
BKX93_RS08435	COG4208	sulfate ABC transporter
BKX93_RS08440	COG3842	ATPase activity
BKX93_RS08445	COG0477	Major facilitator Superfamily
BKX93_RS08470	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BKX93_RS08475	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BKX93_RS08480	COG0330	HflC and HflK could
BKX93_RS08485	COG0330	HflC and HflK could
BKX93_RS08490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKX93_RS08495	COG1923	regulation of RNA biosynthetic process
BKX93_RS08500	COG1160	GTP binding
BKX93_RS08505	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKX93_RS08515	COG0124	histidyl-tRNA synthetase
BKX93_RS08520	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BKX93_RS08535	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BKX93_RS08540	COG0105	UTP biosynthetic process
BKX93_RS08560	COG2807	transmembrane transport
BKX93_RS08570	COG1022	Amp-dependent synthetase and ligase
BKX93_RS08580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKX93_RS08585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKX93_RS08610	COG2974	May be involved in recombination
BKX93_RS08615	COG0753	catalase activity
BKX93_RS08620	COG3384	dioxygenase
BKX93_RS08625	COG0167	dihydroorotate dehydrogenase activity
BKX93_RS08630	COG2193	ferroxidase activity
BKX93_RS08635	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BKX93_RS08645	COG0717	Belongs to the dCTP deaminase family
BKX93_RS08650	COG0386	Belongs to the glutathione peroxidase family
BKX93_RS08665	COG3012	SEC-C Motif Domain Protein
BKX93_RS08680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKX93_RS08710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BKX93_RS08715	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BKX93_RS08720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BKX93_RS08725	COG0196	riboflavin kinase activity
BKX93_RS08740	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKX93_RS08745	COG0175	sulfate reduction
BKX93_RS08750	COG0583	DNA-binding transcription factor activity
BKX93_RS08755	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS08760	COG0488	(ABC) transporter
BKX93_RS08765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKX93_RS08770	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BKX93_RS08775	COG2850	peptidyl-arginine hydroxylation
BKX93_RS08795	COG2239	Acts as a magnesium transporter
BKX93_RS08800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKX93_RS08805	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKX93_RS08815	COG0174	glutamine synthetase
BKX93_RS08825	COG3852	Histidine kinase
BKX93_RS08850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKX93_RS08875	COG0583	DNA-binding transcription factor activity
BKX93_RS08880	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKX93_RS08890	COG1346	cytolysis
BKX93_RS08895	COG1380	Effector of murein hydrolase LrgA
BKX93_RS08900	COG3161	chorismate lyase activity
BKX93_RS08905	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BKX93_RS08920	COG0494	nUDIX hydrolase
BKX93_RS08940	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BKX93_RS08945	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BKX93_RS08955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BKX93_RS08955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKX93_RS08960	COG0038	chloride channel
BKX93_RS08965	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BKX93_RS08970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BKX93_RS08985	COG0583	DNA-binding transcription factor activity
BKX93_RS08990	COG1247	-acetyltransferase
BKX93_RS09000	COG1247	-acetyltransferase
BKX93_RS09020	COG1115	amino acid carrier protein
BKX93_RS09030	COG0584	glycerophosphoryl diester phosphodiesterase
BKX93_RS09035	COG3842	ATPase activity
BKX93_RS09040	COG0395	ABC-type sugar transport system, permease component
BKX93_RS09045	COG1175	transmembrane transport
BKX93_RS09050	COG1653	transport
BKX93_RS09055	COG1294	oxidase, subunit
BKX93_RS09060	COG1271	oxidase subunit
BKX93_RS09075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BKX93_RS09080	COG0456	acetyltransferase
BKX93_RS09085	COG0359	binds to the 23S rRNA
BKX93_RS09090	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BKX93_RS09100	COG0360	Binds together with S18 to 16S ribosomal RNA
BKX93_RS09110	COG1937	Protein conserved in bacteria
BKX93_RS09135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKX93_RS09140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKX93_RS09145	COG0840	transmembrane signaling receptor activity
BKX93_RS09155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BKX93_RS09185	COG1278	Cold shock
BKX93_RS09190	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BKX93_RS09195	COG0542	response to heat
BKX93_RS09205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKX93_RS09210	COG0335	large ribosomal subunit rRNA binding
BKX93_RS09215	COG0336	Belongs to the RNA methyltransferase TrmD family
BKX93_RS09220	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BKX93_RS09225	COG0228	four-way junction DNA binding
BKX93_RS09230	COG0045	succinate-CoA ligase (ADP-forming) activity
BKX93_RS09230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKX93_RS09230	COG1042	CoA-binding domain protein
BKX93_RS09235	COG1230	cation diffusion facilitator family transporter
BKX93_RS09240	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BKX93_RS09245	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BKX93_RS09250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKX93_RS09260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKX93_RS09275	COG0714	Associated with various cellular activities
BKX93_RS09280	COG0123	including yeast histone deacetylase and acetoin utilization protein
BKX93_RS09285	COG0681	Belongs to the peptidase S26 family
BKX93_RS09290	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BKX93_RS09310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKX93_RS09315	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BKX93_RS09320	COG0316	Belongs to the HesB IscA family
BKX93_RS09325	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BKX93_RS09330	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BKX93_RS09335	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BKX93_RS09340	COG0813	purine-nucleoside phosphorylase activity
BKX93_RS09345	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BKX93_RS09350	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BKX93_RS09355	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BKX93_RS09360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKX93_RS09375	COG2095	MarC family integral membrane protein
BKX93_RS09380	COG1301	dicarboxylic acid transport
BKX93_RS09395	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BKX93_RS09400	COG0023	Translation Initiation Factor
BKX93_RS09425	COG3045	CreA protein
BKX93_RS09430	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BKX93_RS09430	COG0321	lipoyl(octanoyl) transferase activity
BKX93_RS09440	COG0084	hydrolase, TatD family'
BKX93_RS09455	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BKX93_RS09460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BKX93_RS09490	COG2186	Transcriptional regulator
BKX93_RS09495	COG2807	transmembrane transport
BKX93_RS09505	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BKX93_RS09510	COG4181	ATPase activity
BKX93_RS09525	COG0450	alkyl hydroperoxide reductase
BKX93_RS09530	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BKX93_RS09545	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BKX93_RS09555	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BKX93_RS09565	COG0268	Binds directly to 16S ribosomal RNA
BKX93_RS09575	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BKX93_RS09575	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BKX93_RS09580	COG0564	pseudouridine synthase activity
BKX93_RS09585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKX93_RS09590	COG2258	MOSC domain
BKX93_RS09595	COG3104	oligopeptide transport
BKX93_RS09600	COG0583	DNA-binding transcription factor activity
BKX93_RS09615	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BKX93_RS09645	COG1610	YqeY-like protein
BKX93_RS09650	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BKX93_RS09655	COG2022	thiamine diphosphate biosynthetic process
BKX93_RS09665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKX93_RS09670	COG1758	RNA polymerase activity
BKX93_RS09675	COG0194	GDP metabolic process
BKX93_RS09680	COG2252	PERMEase
BKX93_RS09685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKX93_RS09705	COG1695	Transcriptional regulator
BKX93_RS09720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKX93_RS09725	COG2235	arginine
BKX93_RS09735	COG0543	2 iron, 2 sulfur cluster binding
BKX93_RS09735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKX93_RS09745	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BKX93_RS09750	COG0386	Belongs to the glutathione peroxidase family
BKX93_RS09760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKX93_RS09775	COG0586	Pfam SNARE associated Golgi protein
BKX93_RS09780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BKX93_RS09795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKX93_RS09805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKX93_RS09810	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BKX93_RS09815	COG1534	Rna-binding protein
BKX93_RS09905	COG1960	acyl-CoA dehydrogenase activity
BKX93_RS09920	COG2030	dehydratase
BKX93_RS09930	COG0802	atpase or kinase
BKX93_RS09935	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKX93_RS09940	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BKX93_RS09945	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BKX93_RS09950	COG0237	dephospho-CoA kinase activity
BKX93_RS09955	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BKX93_RS09975	COG1596	polysaccharide export
BKX93_RS09975	COG1555	photosystem II stabilization
BKX93_RS09980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKX93_RS09985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BKX93_RS10010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKX93_RS10015	COG1538	Outer membrane efflux protein
BKX93_RS10020	COG3383	formate dehydrogenase (NAD+) activity
BKX93_RS10020	COG0243	molybdopterin cofactor binding
BKX93_RS10025	COG0437	4 iron, 4 sulfur cluster binding
BKX93_RS10030	COG2864	formate dehydrogenase
BKX93_RS10040	COG0745	RESPONSE REGULATOR receiver
BKX93_RS10045	COG2205	protein histidine kinase activity
BKX93_RS10055	COG3591	Belongs to the peptidase S1B family
BKX93_RS10060	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BKX93_RS10065	COG0631	protein serine/threonine phosphatase activity
BKX93_RS10070	COG0515	serine threonine protein kinase
BKX93_RS10070	COG1357	PFAM Pentapeptide repeats (8 copies)
BKX93_RS10075	COG1561	YicC-like family, N-terminal region
BKX93_RS10100	COG0776	regulation of translation
BKX93_RS10105	COG2084	Dehydrogenase
BKX93_RS10110	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKX93_RS10155	COG0438	transferase activity, transferring glycosyl groups
BKX93_RS10155	COG1216	Glycosyl transferase, family 2
BKX93_RS10170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKX93_RS10180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKX93_RS10190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKX93_RS10195	COG0028	Belongs to the TPP enzyme family
BKX93_RS10200	COG2089	acid synthase
BKX93_RS10235	COG3720	iron ion transport
BKX93_RS10245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKX93_RS10250	COG1120	ATPase activity
BKX93_RS10255	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BKX93_RS10260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKX93_RS10270	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKX93_RS10280	COG1846	Transcriptional regulator
BKX93_RS10290	COG2223	nitrite transmembrane transporter activity
BKX93_RS10300	COG1678	Uncharacterized ACR, COG1678
BKX93_RS10305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BKX93_RS10320	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BKX93_RS10325	COG3530	Putative quorum-sensing-regulated virulence factor
BKX93_RS10340	COG0644	oxidoreductase
BKX93_RS10340	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BKX93_RS10350	COG1960	acyl-CoA dehydrogenase activity
BKX93_RS10360	COG0517	IMP dehydrogenase activity
BKX93_RS10360	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BKX93_RS10365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BKX93_RS10370	COG1309	transcriptional regulator
BKX93_RS10380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKX93_RS10385	COG1538	Outer membrane efflux protein
BKX93_RS10390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BKX93_RS10430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BKX93_RS10470	COG0642	Histidine kinase
BKX93_RS10480	COG0671	phosphoesterase, PA-phosphatase related
BKX93_RS10510	COG0386	Belongs to the glutathione peroxidase family
BKX93_RS10535	COG0010	Belongs to the arginase family
BKX93_RS10545	COG0109	protoheme IX farnesyltransferase activity
BKX93_RS10565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKX93_RS10585	COG0606	chelatase, subunit chli
BKX93_RS10660	COG0798	PFAM Bile acid sodium symporter
BKX93_RS10665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKX93_RS10670	COG0346	lactoylglutathione lyase activity
BKX93_RS10680	COG2814	Major facilitator Superfamily
BKX93_RS10700	COG0347	Belongs to the P(II) protein family
BKX93_RS10705	COG0004	ammonium transporteR
BKX93_RS10710	COG2969	positive regulation of protein catabolic process
BKX93_RS10715	COG0625	glutathione transferase activity
BKX93_RS10720	COG2857	Cytochrome c1
BKX93_RS10725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKX93_RS10730	COG0723	plastoquinol--plastocyanin reductase activity
BKX93_RS10735	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BKX93_RS10745	COG1091	dTDP-4-dehydrorhamnose reductase activity
BKX93_RS10760	COG0459	protein refolding
BKX93_RS10770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKX93_RS10835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKX93_RS10840	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BKX93_RS10850	COG1132	(ABC) transporter
BKX93_RS10865	COG0859	PFAM glycosyl transferase family 9
BKX93_RS10870	COG0438	transferase activity, transferring glycosyl groups
BKX93_RS10885	COG1216	Glycosyl transferase, family 2
BKX93_RS10895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKX93_RS10910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BKX93_RS10910	COG1648	precorrin-2 dehydrogenase activity
BKX93_RS10915	COG3706	GGDEF domain
BKX93_RS10925	COG1295	ribonuclease BN
BKX93_RS10925	COG1959	2 iron, 2 sulfur cluster binding
BKX93_RS10935	COG0583	DNA-binding transcription factor activity
BKX93_RS10945	COG2957	Belongs to the agmatine deiminase family
BKX93_RS10955	COG0154	amidase activity
BKX93_RS10985	COG0280	phosphate acetyltransferase
BKX93_RS10985	COG0281	malic enzyme
BKX93_RS11000	COG2990	Protein conserved in bacteria
BKX93_RS11005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKX93_RS11020	COG3511	phospholipase C
BKX93_RS11035	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKX93_RS11040	COG0625	glutathione transferase activity
BKX93_RS11065	COG0318	PFAM AMP-dependent synthetase and ligase
BKX93_RS11070	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BKX93_RS11095	COG0642	Histidine kinase
BKX93_RS11100	COG0745	RESPONSE REGULATOR receiver
BKX93_RS11110	COG0438	transferase activity, transferring glycosyl groups
BKX93_RS11135	COG0708	Exodeoxyribonuclease III
BKX93_RS11145	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BKX93_RS11155	COG0840	transmembrane signaling receptor activity
BKX93_RS11160	COG0531	amino acid
BKX93_RS11170	COG1770	oligopeptidase
BKX93_RS11180	COG0848	biopolymer transport protein
BKX93_RS11230	COG1196	nuclear chromosome segregation
BKX93_RS11265	COG4598	ABC transporter
BKX93_RS11270	COG4160	amino acid transport
BKX93_RS11275	COG4215	(ABC) transporter
BKX93_RS11285	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BKX93_RS11290	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BKX93_RS11295	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BKX93_RS11300	COG0142	geranyltranstransferase activity
BKX93_RS11310	COG0582	viral genome integration into host DNA
BKX93_RS11380	COG2223	nitrite transmembrane transporter activity
BKX93_RS11420	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BKX93_RS11425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKX93_RS11430	COG1242	4 iron, 4 sulfur cluster binding
BKX93_RS11440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKX93_RS11445	COG2813	Specifically methylates the guanine in position
BKX93_RS11445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BKX93_RS11455	COG2814	Major facilitator Superfamily
BKX93_RS11500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKX93_RS11530	COG1393	Belongs to the ArsC family
BKX93_RS11535	COG1846	Transcriptional regulator
BKX93_RS11540	COG1538	Outer membrane efflux protein
BKX93_RS11550	COG2814	Major facilitator Superfamily
BKX93_RS11555	COG0583	DNA-binding transcription factor activity
BKX93_RS11560	COG2855	membrane
BKX93_RS11570	COG1966	Carbon starvation protein
BKX93_RS11575	COG0745	RESPONSE REGULATOR receiver
BKX93_RS11580	COG2205	protein histidine kinase activity
BKX93_RS11595	COG0408	coproporphyrinogen oxidase activity
BKX93_RS11600	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKX93_RS11605	COG2076	Multidrug Resistance protein
BKX93_RS11610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKX93_RS11615	COG0463	Glycosyl transferase, family 2
BKX93_RS11625	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKX93_RS11625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKX93_RS11635	COG0726	polysaccharide deacetylase
BKX93_RS11665	COG0583	DNA-binding transcription factor activity
BKX93_RS11670	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BKX93_RS11690	COG1595	DNA-templated transcription, initiation
BKX93_RS11745	COG0477	Major facilitator Superfamily
BKX93_RS11750	COG0583	DNA-binding transcription factor activity
BKX93_RS11760	COG2910	NAD(P)H-binding
BKX93_RS11790	COG1309	transcriptional regulator
BKX93_RS11805	COG2814	Major facilitator Superfamily
BKX93_RS11820	COG0656	L-ascorbic acid biosynthetic process
BKX93_RS11830	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BKX93_RS11840	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS11875	COG2239	Acts as a magnesium transporter
BKX93_RS11905	COG2201	protein-glutamate methylesterase activity
BKX93_RS11910	COG2198	Histidine kinase
BKX93_RS11910	COG0643	Histidine kinase
BKX93_RS11930	COG0657	acetylesterase activity
BKX93_RS11945	COG1309	transcriptional regulator
BKX93_RS11960	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS11965	COG1064	alcohol dehydrogenase
BKX93_RS11975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKX93_RS11980	COG1349	DNA-binding transcription factor activity
BKX93_RS11985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BKX93_RS11990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BKX93_RS11995	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BKX93_RS12000	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BKX93_RS12005	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BKX93_RS12010	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKX93_RS12015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BKX93_RS12025	COG0356	it plays a direct role in the translocation of protons across the membrane
BKX93_RS12040	COG1192	Involved in chromosome partitioning
BKX93_RS12045	COG0357	Ribosomal RNA small subunit methyltransferase G
BKX93_RS12050	COG0445	tRNA wobble uridine modification
BKX93_RS12065	COG1720	tRNA m6t6A37 methyltransferase activity
BKX93_RS12075	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BKX93_RS12080	COG2823	Periplasmic or secreted lipoprotein
BKX93_RS12085	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BKX93_RS12090	COG0792	nuclease activity
BKX93_RS12110	COG0582	viral genome integration into host DNA
BKX93_RS12165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BKX93_RS12170	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKX93_RS12195	COG3781	membrane
BKX93_RS12200	COG1132	(ABC) transporter
BKX93_RS12205	COG1132	(ABC) transporter
BKX93_RS12210	COG0494	nUDIX hydrolase
BKX93_RS12220	COG0084	hydrolase, TatD family'
BKX93_RS12240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKX93_RS12245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKX93_RS12255	COG0140	phosphoribosyl-ATP diphosphatase activity
BKX93_RS12260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BKX93_RS12265	COG0107	imidazoleglycerol-phosphate synthase activity
BKX93_RS12270	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BKX93_RS12275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BKX93_RS12280	COG0131	Imidazoleglycerol-phosphate dehydratase
BKX93_RS12285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKX93_RS12295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BKX93_RS12300	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BKX93_RS12305	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BKX93_RS12310	COG1999	signal sequence binding
BKX93_RS12315	COG0109	protoheme IX farnesyltransferase activity
BKX93_RS12320	COG1612	heme a metabolic process
BKX93_RS12350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKX93_RS12355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKX93_RS12360	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BKX93_RS12370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKX93_RS12390	COG0688	phosphatidylethanolamine metabolic process
BKX93_RS12400	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BKX93_RS12405	COG0440	acetolactate synthase activity
BKX93_RS12410	COG0028	Belongs to the TPP enzyme family
BKX93_RS12445	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKX93_RS12455	COG0402	S-adenosylhomocysteine deaminase activity
BKX93_RS12465	COG1914	H( )-stimulated, divalent metal cation uptake system
BKX93_RS12470	COG0741	lytic transglycosylase activity
BKX93_RS12475	COG0442	prolyl-tRNA aminoacylation
BKX93_RS12480	COG3158	transport of potassium into the cell
BKX93_RS12500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BKX93_RS12500	COG0512	Glutamine amidotransferase of anthranilate synthase
BKX93_RS12515	COG3945	hemerythrin HHE cation binding domain
BKX93_RS12530	COG0745	RESPONSE REGULATOR receiver
BKX93_RS12535	COG1522	sequence-specific DNA binding
BKX93_RS12540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKX93_RS12550	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKX93_RS12550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKX93_RS12555	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKX93_RS12560	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BKX93_RS12565	COG2188	Transcriptional regulator
BKX93_RS12575	COG0697	spore germination
BKX93_RS12580	COG0811	peptide transport
BKX93_RS12585	COG0009	L-threonylcarbamoyladenylate synthase
BKX93_RS12635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKX93_RS12640	COG0151	Belongs to the GarS family
BKX93_RS12645	COG0138	bifunctional purine biosynthesis protein purh
BKX93_RS12710	COG0456	acetyltransferase
BKX93_RS12715	COG3447	MASE1 domain protein
BKX93_RS12715	COG5002	protein histidine kinase activity
BKX93_RS12715	COG5001	Diguanylate cyclase
BKX93_RS12735	COG1943	Transposase
BKX93_RS12745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKX93_RS12750	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKX93_RS12755	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BKX93_RS12775	COG1584	GPR1 FUN34 yaaH family protein
BKX93_RS12780	COG0288	reversible hydration of carbon dioxide
BKX93_RS12785	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BKX93_RS12790	COG0799	negative regulation of ribosome biogenesis
BKX93_RS12795	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BKX93_RS12800	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BKX93_RS12805	COG0438	transferase activity, transferring glycosyl groups
BKX93_RS12820	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BKX93_RS12835	COG1466	dna polymerase III delta subunit
BKX93_RS12845	COG0495	leucyl-tRNA aminoacylation
BKX93_RS12855	COG0730	response to heat
BKX93_RS12875	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BKX93_RS12895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKX93_RS12905	COG4206	TonB-dependent receptor
BKX93_RS12910	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BKX93_RS12920	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BKX93_RS12935	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BKX93_RS12945	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BKX93_RS13005	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BKX93_RS13010	COG0514	ATP-dependent DNA helicase (RecQ)
BKX93_RS13020	COG1192	Involved in chromosome partitioning
BKX93_RS13025	COG2205	protein histidine kinase activity
BKX93_RS13080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKX93_RS13090	COG2124	cytochrome p450
BKX93_RS13100	COG0640	Transcriptional regulator
BKX93_RS13115	COG2056	Na+-H+ antiporter family
BKX93_RS13120	COG2900	Belongs to the SlyX family
BKX93_RS13135	COG0456	acetyltransferase
BKX93_RS13145	COG0436	Aminotransferase
BKX93_RS13150	COG2171	N-acyltransferase activity
BKX93_RS13155	COG1127	ABC transporter
BKX93_RS13160	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKX93_RS13165	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BKX93_RS13185	COG2824	Alkylphosphonate utilization operon protein PhnA
BKX93_RS13195	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKX93_RS13205	COG0842	Transport permease protein
BKX93_RS13210	COG1131	(ABC) transporter
BKX93_RS13440	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BKX93_RS13445	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BKX93_RS13470	COG0840	transmembrane signaling receptor activity
BKX93_RS13480	COG2226	methyltransferase
BKX93_RS13485	COG1012	belongs to the aldehyde dehydrogenase family
BKX93_RS13490	COG3284	Transcriptional regulator
BKX93_RS13495	COG0583	DNA-binding transcription factor activity
BKX93_RS13500	COG2249	NAD(P)H dehydrogenase (quinone) activity
BKX93_RS13515	COG3920	Histidine kinase
BKX93_RS13515	COG2202	Pas domain
BKX93_RS13530	COG0513	Belongs to the DEAD box helicase family
BKX93_RS13540	COG4681	YaeQ
BKX93_RS13555	COG1451	nucleotide metabolic process
BKX93_RS13565	COG1879	ABC-type sugar transport system periplasmic component
BKX93_RS13590	COG0038	chloride channel
BKX93_RS13595	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BKX93_RS13600	COG0540	Belongs to the ATCase OTCase family
BKX93_RS13610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BKX93_RS13620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BKX93_RS13625	COG3240	lipase activity
BKX93_RS13630	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BKX93_RS13630	COG0116	Belongs to the methyltransferase superfamily
BKX93_RS13635	COG3240	lipase activity
BKX93_RS13645	COG0657	acetylesterase activity
BKX93_RS13650	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BKX93_RS13680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BKX93_RS13765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKX93_RS13780	COG1448	Aminotransferase
BKX93_RS13795	COG1943	Transposase
BKX93_RS13805	COG2986	histidine ammonia-lyase
BKX93_RS13810	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BKX93_RS13815	COG0010	Belongs to the arginase family
BKX93_RS13820	COG1228	amidohydrolase
BKX93_RS13835	COG0676	glucose-6-phosphate 1-epimerase activity
BKX93_RS13855	COG0625	glutathione transferase activity
BKX93_RS13890	COG5001	Diguanylate cyclase
BKX93_RS13900	COG1538	Outer membrane efflux protein
BKX93_RS13910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKX93_RS13915	COG2197	response regulator
BKX93_RS13920	COG2962	Rard protein
BKX93_RS13935	COG1858	cytochrome C peroxidase
BKX93_RS13940	COG0583	DNA-binding transcription factor activity
BKX93_RS13950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKX93_RS13960	COG0737	Belongs to the 5'-nucleotidase family
BKX93_RS13965	COG0625	glutathione transferase activity
BKX93_RS13975	COG4628	conserved protein (DUF2132)
BKX93_RS14070	COG1733	regulation of RNA biosynthetic process
BKX93_RS14075	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS14090	COG0826	peptidase U32
BKX93_RS14105	COG1653	transport
BKX93_RS14110	COG1175	transmembrane transport
BKX93_RS14115	COG0395	ABC-type sugar transport system, permease component
BKX93_RS14120	COG1472	Belongs to the glycosyl hydrolase 3 family
BKX93_RS14125	COG3842	ATPase activity
BKX93_RS14140	COG2814	Major facilitator Superfamily
BKX93_RS14160	COG2271	Major facilitator Superfamily
BKX93_RS14165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BKX93_RS14170	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKX93_RS14175	COG0469	pyruvate kinase activity
BKX93_RS14195	COG3214	Protein conserved in bacteria
BKX93_RS14220	COG2203	Gaf domain
BKX93_RS14220	COG2199	diguanylate cyclase activity
BKX93_RS14240	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BKX93_RS14245	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKX93_RS14250	COG1054	Belongs to the UPF0176 family
BKX93_RS14255	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BKX93_RS14260	COG1253	flavin adenine dinucleotide binding
BKX93_RS14280	COG0463	Glycosyl transferase, family 2
BKX93_RS14285	COG0859	PFAM glycosyl transferase family 9
BKX93_RS14300	COG3161	chorismate lyase activity
BKX93_RS14325	COG0583	DNA-binding transcription factor activity
BKX93_RS14360	COG3150	esterase
BKX93_RS14370	COG1846	Transcriptional regulator
BKX93_RS14375	COG1764	response to oxidative stress
BKX93_RS14395	COG0210	DNA helicase
BKX93_RS14405	COG1410	methionine synthase
BKX93_RS14405	COG0646	methionine synthase
BKX93_RS14450	COG0625	glutathione transferase activity
BKX93_RS14455	COG4122	O-methyltransferase activity
BKX93_RS14465	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BKX93_RS14470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKX93_RS14475	COG0126	phosphoglycerate kinase activity
BKX93_RS14480	COG1280	lysine exporter protein (LysE YggA)
BKX93_RS14490	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BKX93_RS14495	COG0314	molybdopterin synthase activity
BKX93_RS14510	COG0745	RESPONSE REGULATOR receiver
BKX93_RS14540	COG0762	integral membrane protein
BKX93_RS14545	COG4654	Cytochrome c, class I
BKX93_RS14555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BKX93_RS14575	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKX93_RS14575	COG1902	pentaerythritol trinitrate reductase activity
BKX93_RS14595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKX93_RS14600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKX93_RS14605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BKX93_RS14620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BKX93_RS14650	COG2954	triphosphatase activity
BKX93_RS14655	COG1981	membrane
BKX93_RS14675	COG0351	phosphomethylpyrimidine kinase
BKX93_RS14680	COG0352	thiamine-phosphate diphosphorylase activity
BKX93_RS14690	COG0166	Belongs to the GPI family
BKX93_RS14695	COG1737	Transcriptional regulator
BKX93_RS14695	COG0837	glucose binding
BKX93_RS14700	COG0837	glucose binding
BKX93_RS14710	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BKX93_RS14720	COG0800	Aldolase
BKX93_RS14725	COG0583	DNA-binding transcription factor activity
BKX93_RS14730	COG2814	Major facilitator Superfamily
BKX93_RS14745	COG2199	diguanylate cyclase activity
BKX93_RS14745	COG2203	Gaf domain
BKX93_RS14745	COG2200	EAL domain
BKX93_RS14755	COG0579	oxidoreductase
BKX93_RS14765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKX93_RS14775	COG3135	benzoate transporter
BKX93_RS14780	COG0006	proline dipeptidase activity
BKX93_RS14800	COG1530	ribonuclease E activity
BKX93_RS14805	COG0424	maF-like protein
BKX93_RS14815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKX93_RS14825	COG0765	amino acid transport
BKX93_RS14830	COG0765	amino acid transport
BKX93_RS14835	COG1126	abc transporter atp-binding protein
BKX93_RS14845	COG0165	Argininosuccinate lyase
BKX93_RS14850	COG2200	EAL domain
BKX93_RS14885	COG0823	Involved in the tonB-independent uptake of proteins
BKX93_RS14915	COG0745	RESPONSE REGULATOR receiver
BKX93_RS14915	COG2972	Histidine kinase
BKX93_RS14925	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS14935	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BKX93_RS14975	COG0318	PFAM AMP-dependent synthetase and ligase
BKX93_RS14980	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BKX93_RS15000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKX93_RS15035	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BKX93_RS15040	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BKX93_RS15045	COG4771	TonB-dependent receptor
BKX93_RS15050	COG2153	protein acetylation
BKX93_RS15095	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKX93_RS15115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKX93_RS15135	COG0583	DNA-binding transcription factor activity
BKX93_RS15145	COG0259	pyridoxamine-phosphate oxidase activity
BKX93_RS15160	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BKX93_RS15165	COG0181	hydroxymethylbilane synthase activity
BKX93_RS15170	COG1587	Uroporphyrinogen-III synthase
BKX93_RS15175	COG2959	enzyme of heme biosynthesis
BKX93_RS15185	COG0583	DNA-binding transcription factor activity
BKX93_RS15190	COG0477	Major facilitator Superfamily
BKX93_RS15200	COG4251	negative regulation of phosphorylation
BKX93_RS15200	COG2203	Gaf domain
BKX93_RS15200	COG3706	GGDEF domain
BKX93_RS15200	COG5001	Diguanylate cyclase
BKX93_RS15210	COG1045	serine acetyltransferase
BKX93_RS15230	COG1965	Belongs to the frataxin family
BKX93_RS15245	COG5654	RES domain protein
BKX93_RS15250	COG5642	Protein of unknown function (DUF2384)
BKX93_RS15255	COG0840	transmembrane signaling receptor activity
BKX93_RS15265	COG0583	DNA-binding transcription factor activity
BKX93_RS15335	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKX93_RS15340	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BKX93_RS15345	COG0594	ribonuclease P activity
BKX93_RS15350	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BKX93_RS15355	COG0706	membrane insertase activity
BKX93_RS15360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BKX93_RS15370	COG2198	Histidine kinase
BKX93_RS15370	COG0784	Response regulator, receiver
BKX93_RS15370	COG5002	protein histidine kinase activity
BKX93_RS15385	COG1174	glycine betaine transport
BKX93_RS15390	COG1125	glycine betaine transport
BKX93_RS15395	COG1174	glycine betaine transport
BKX93_RS15400	COG1732	Glycine betaine
BKX93_RS15405	COG2827	Endonuclease containing a URI domain
BKX93_RS15410	COG1253	flavin adenine dinucleotide binding
BKX93_RS15415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKX93_RS15430	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BKX93_RS15440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BKX93_RS15450	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BKX93_RS15455	COG0156	8-amino-7-oxononanoate synthase activity
BKX93_RS15465	COG2226	methyltransferase
BKX93_RS15470	COG2267	carboxylic ester hydrolase activity
BKX93_RS15475	COG2226	methyltransferase
BKX93_RS15485	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKX93_RS15490	COG0625	glutathione transferase activity
BKX93_RS15515	COG0733	neurotransmitter:sodium symporter activity
BKX93_RS15525	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BKX93_RS15540	COG2847	Copper chaperone PCu(A)C
BKX93_RS15550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKX93_RS15555	COG0612	Peptidase, M16
BKX93_RS15560	COG0772	Belongs to the SEDS family
BKX93_RS15565	COG0768	penicillin binding
BKX93_RS15570	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BKX93_RS15575	COG1792	Involved in formation and maintenance of cell shape
BKX93_RS15580	COG1077	Cell shape determining protein MreB Mrl
BKX93_RS15585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKX93_RS15590	COG0154	amidase activity
BKX93_RS15595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKX93_RS15600	COG2001	Belongs to the MraZ family
BKX93_RS15605	COG0275	rRNA processing
BKX93_RS15610	COG3116	cell division
BKX93_RS15620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BKX93_RS15625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BKX93_RS15630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKX93_RS15635	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BKX93_RS15640	COG0772	Belongs to the SEDS family
BKX93_RS15645	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKX93_RS15650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKX93_RS15655	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKX93_RS15660	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BKX93_RS15675	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BKX93_RS15685	COG0315	cyclic pyranopterin monophosphate synthase activity
BKX93_RS15690	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS15730	COG0425	Belongs to the sulfur carrier protein TusA family
BKX93_RS15735	COG0418	dihydroorotase activity
BKX93_RS15745	COG0601	transmembrane transport
BKX93_RS15750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKX93_RS15760	COG4608	Belongs to the ABC transporter superfamily
BKX93_RS15775	COG0393	Putative heavy-metal-binding
BKX93_RS15805	COG2134	cdp-diacylglycerol pyrophosphatase
BKX93_RS15815	COG0346	lactoylglutathione lyase activity
BKX93_RS15820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BKX93_RS15855	COG1505	serine-type exopeptidase activity
BKX93_RS15860	COG3590	peptidase
BKX93_RS15890	COG3132	Protein of unknown function, DUF480
BKX93_RS15895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BKX93_RS15900	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BKX93_RS15905	COG0589	response to stress
BKX93_RS15910	COG0174	glutamine synthetase
BKX93_RS15915	COG0840	transmembrane signaling receptor activity
BKX93_RS15940	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BKX93_RS15965	COG1116	anion transmembrane transporter activity
BKX93_RS15975	COG3540	Alkaline phosphatase
BKX93_RS15980	COG0653	protein targeting
BKX93_RS15990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKX93_RS15995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKX93_RS16005	COG0189	ligase activity
BKX93_RS16040	COG2922	Belongs to the Smg family
BKX93_RS16045	COG0758	DNA mediated transformation
BKX93_RS16055	COG0242	peptide deformylase activity
BKX93_RS16060	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKX93_RS16065	COG0501	Belongs to the peptidase M48B family
BKX93_RS16070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKX93_RS16070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BKX93_RS16080	COG5000	phosphorelay sensor kinase activity
BKX93_RS16085	COG2204	response regulator
BKX93_RS16090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKX93_RS16095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKX93_RS16100	COG0824	Thioesterase
BKX93_RS16115	COG0783	Belongs to the Dps family
BKX93_RS16120	COG1872	DUF167
BKX93_RS16130	COG1324	tolerance protein
BKX93_RS16180	COG2832	Protein of unknown function (DUF454)
BKX93_RS16195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BKX93_RS16200	COG0708	Exodeoxyribonuclease III
BKX93_RS16225	COG1253	flavin adenine dinucleotide binding
BKX93_RS16240	COG1335	isochorismatase
BKX93_RS16245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKX93_RS16255	COG0592	DNA-directed DNA polymerase activity
BKX93_RS16265	COG0247	lactate metabolic process
BKX93_RS16285	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BKX93_RS16290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKX93_RS16295	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BKX93_RS16310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BKX93_RS16315	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BKX93_RS16325	COG0632	four-way junction helicase activity
BKX93_RS16340	COG2204	response regulator
BKX93_RS16350	COG2205	protein histidine kinase activity
BKX93_RS16355	COG0307	riboflavin synthase, alpha
BKX93_RS16360	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKX93_RS16365	COG2255	four-way junction helicase activity
BKX93_RS16385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BKX93_RS16395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKX93_RS16425	COG2884	Cell division ATP-binding protein ftsE
BKX93_RS16435	COG0742	ribosomal rna small subunit methyltransferase
BKX93_RS16440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BKX93_RS16460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BKX93_RS16470	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKX93_RS16480	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BKX93_RS16485	COG0081	regulation of translation
BKX93_RS16495	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BKX93_RS16500	COG0222	ribosome binding
BKX93_RS16505	COG0085	RNA polymerase activity
BKX93_RS16510	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BKX93_RS16515	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BKX93_RS16520	COG0049	tRNA binding
BKX93_RS16525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BKX93_RS16530	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BKX93_RS16535	COG0051	transcription antitermination factor activity, RNA binding
BKX93_RS16540	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BKX93_RS16545	COG0088	Forms part of the polypeptide exit tunnel
BKX93_RS16550	COG0089	rRNA binding
BKX93_RS16560	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BKX93_RS16565	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BKX93_RS16570	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BKX93_RS16575	COG0255	Belongs to the universal ribosomal protein uL29 family
BKX93_RS16580	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BKX93_RS16585	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BKX93_RS16590	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BKX93_RS16595	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BKX93_RS16605	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BKX93_RS16610	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BKX93_RS16615	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BKX93_RS16620	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BKX93_RS16625	COG1841	ribosomal large subunit assembly
BKX93_RS16630	COG0200	Binds to the 23S rRNA
BKX93_RS16635	COG0201	protein transport
BKX93_RS16640	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BKX93_RS16645	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BKX93_RS16650	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BKX93_RS16655	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BKX93_RS16660	COG0202	RNA polymerase activity
BKX93_RS16665	COG0203	ribosomal protein L17
BKX93_RS16670	COG2066	Belongs to the glutaminase family
BKX93_RS16675	COG0633	Ferredoxin
BKX93_RS16675	COG3217	Mosc domain protein beta barrel domain protein
BKX93_RS16685	COG0840	transmembrane signaling receptor activity
BKX93_RS16690	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BKX93_RS16695	COG4535	Mg2 and Co2 transporter CorC
BKX93_RS16700	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BKX93_RS16705	COG1702	phosphate starvation-inducible protein PhoH
BKX93_RS16720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKX93_RS16730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKX93_RS16730	COG4651	solute:proton antiporter activity
BKX93_RS16750	COG0583	DNA-binding transcription factor activity
BKX93_RS16755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKX93_RS16755	COG1024	Enoyl-CoA hydratase
BKX93_RS16765	COG1960	acyl-CoA dehydrogenase activity
BKX93_RS16790	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS16795	COG0037	tRNA processing
BKX93_RS16800	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BKX93_RS16865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKX93_RS16890	COG0583	DNA-binding transcription factor activity
BKX93_RS16895	COG1027	Aspartate ammonia-lyase
BKX93_RS16920	COG3171	Protein conserved in bacteria
BKX93_RS16940	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BKX93_RS16945	COG3047	cAMP biosynthetic process
BKX93_RS16950	COG3842	ATPase activity
BKX93_RS16965	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BKX93_RS17025	COG1012	belongs to the aldehyde dehydrogenase family
BKX93_RS17030	COG2197	response regulator
BKX93_RS17035	COG0583	DNA-binding transcription factor activity
BKX93_RS17045	COG3154	lipid carrier protein
BKX93_RS17055	COG0826	peptidase U32
BKX93_RS17090	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BKX93_RS17095	COG1074	ATP-dependent DNA helicase activity
BKX93_RS17110	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BKX93_RS17125	COG1132	(ABC) transporter
BKX93_RS17130	COG0583	DNA-binding transcription factor activity
BKX93_RS17160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKX93_RS17190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BKX93_RS17215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKX93_RS17225	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BKX93_RS17230	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BKX93_RS17240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKX93_RS17245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BKX93_RS17250	COG0193	aminoacyl-tRNA hydrolase activity
BKX93_RS17255	COG0012	GTP binding
BKX93_RS17265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKX93_RS17270	COG0765	amino acid transport
BKX93_RS17275	COG1022	Amp-dependent synthetase and ligase
BKX93_RS17300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKX93_RS17315	COG1280	lysine exporter protein (LysE YggA)
BKX93_RS17320	COG2199	diguanylate cyclase activity
BKX93_RS17335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKX93_RS17340	COG0067	glutamate synthase
BKX93_RS17340	COG0070	glutamate synthase
BKX93_RS17340	COG0069	glutamate synthase activity
BKX93_RS17345	COG0493	'glutamate synthase
BKX93_RS17375	COG2801	Transposase and inactivated derivatives
BKX93_RS17520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BKX93_RS17525	COG0367	asparagine synthase
BKX93_RS17530	COG0142	geranyltranstransferase activity
BKX93_RS17550	COG0142	geranyltranstransferase activity
BKX93_RS17560	COG4106	trans-aconitate 2-methyltransferase activity
BKX93_RS17570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKX93_RS17575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKX93_RS17585	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS17590	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKX93_RS17590	COG1902	pentaerythritol trinitrate reductase activity
BKX93_RS17605	COG0577	efflux transmembrane transporter activity
BKX93_RS17605	COG1136	(ABC) transporter
BKX93_RS17610	COG0577	efflux transmembrane transporter activity
BKX93_RS17610	COG1136	(ABC) transporter
BKX93_RS17640	COG0747	negative chemotaxis
BKX93_RS17665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BKX93_RS17670	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BKX93_RS17675	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BKX93_RS17680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKX93_RS17710	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BKX93_RS17715	COG0306	phosphate transporter
BKX93_RS17720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKX93_RS17725	COG0581	inorganic phosphate transmembrane transporter activity
BKX93_RS17740	COG0149	triose-phosphate isomerase activity
BKX93_RS17745	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKX93_RS17755	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKX93_RS17760	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKX93_RS17765	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKX93_RS17770	COG0649	NAD binding
BKX93_RS17790	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BKX93_RS17795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKX93_RS17805	COG0713	ATP synthesis coupled electron transport
BKX93_RS17820	COG1007	ATP synthesis coupled electron transport
BKX93_RS17850	COG1560	Kdo2-lipid A biosynthetic process
BKX93_RS17860	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BKX93_RS17865	COG3706	GGDEF domain
BKX93_RS17870	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BKX93_RS17875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BKX93_RS17885	COG1522	sequence-specific DNA binding
BKX93_RS17895	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BKX93_RS17905	COG0625	glutathione transferase activity
BKX93_RS17925	COG0561	phosphatase activity
BKX93_RS17930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKX93_RS17945	COG2259	Doxx family
BKX93_RS17950	COG0583	DNA-binding transcription factor activity
BKX93_RS17965	COG2264	protein methyltransferase activity
BKX93_RS17970	COG0439	Biotin carboxylase
BKX93_RS17975	COG0511	ligase activity, forming carbon-carbon bonds
BKX93_RS17980	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BKX93_RS17985	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BKX93_RS17995	COG2226	methyltransferase
BKX93_RS18005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BKX93_RS18010	COG1252	NADH dehydrogenase
BKX93_RS18025	COG0436	Aminotransferase
BKX93_RS18050	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BKX93_RS18065	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BKX93_RS18070	COG0513	Belongs to the DEAD box helicase family
BKX93_RS18095	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKX93_RS18100	COG2199	diguanylate cyclase activity
BKX93_RS18100	COG2200	EAL domain
BKX93_RS18100	COG2202	Pas domain
BKX93_RS18105	COG2201	protein-glutamate methylesterase activity
BKX93_RS18110	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BKX93_RS18115	COG0840	transmembrane signaling receptor activity
BKX93_RS18120	COG0835	chemotaxis
BKX93_RS18130	COG0643	Histidine kinase
BKX93_RS18130	COG2198	Histidine kinase
BKX93_RS18140	COG0745	RESPONSE REGULATOR receiver
BKX93_RS18150	COG0527	aspartate kinase activity
BKX93_RS18170	COG4206	TonB-dependent receptor
BKX93_RS18195	COG0322	excinuclease ABC activity
BKX93_RS18205	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BKX93_RS18235	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BKX93_RS18250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKX93_RS18255	COG0402	S-adenosylhomocysteine deaminase activity
BKX93_RS18280	COG0277	FAD linked oxidase domain protein
BKX93_RS18280	COG0277	FAD linked oxidase domain protein
BKX93_RS18290	COG3469	chitinase activity
BKX93_RS18350	COG4221	oxidoreductase activity
BKX93_RS18365	COG2801	Transposase and inactivated derivatives
BKX93_RS18370	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BKX93_RS18375	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BKX93_RS18380	COG0039	L-malate dehydrogenase activity
BKX93_RS18385	COG2188	Transcriptional regulator
BKX93_RS18390	COG2009	succinate dehydrogenase
BKX93_RS18400	COG1053	succinate dehydrogenase
BKX93_RS18405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BKX93_RS18410	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BKX93_RS18420	COG0567	Dehydrogenase, E1 component
BKX93_RS18425	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKX93_RS18435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKX93_RS18440	COG0045	succinate-CoA ligase (ADP-forming) activity
BKX93_RS18455	COG0477	Major facilitator Superfamily
BKX93_RS18460	COG0583	DNA-binding transcription factor activity
BKX93_RS18465	COG0840	transmembrane signaling receptor activity
BKX93_RS18470	COG0840	transmembrane signaling receptor activity
BKX93_RS18490	COG0572	uridine kinase
BKX93_RS18505	COG0633	Ferredoxin
BKX93_RS18510	COG0443	Heat shock 70 kDa protein
BKX93_RS18515	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BKX93_RS18525	COG0822	iron-sulfur transferase activity
BKX93_RS18530	COG1104	cysteine desulfurase activity
BKX93_RS18545	COG0747	negative chemotaxis
BKX93_RS18550	COG0601	transmembrane transport
BKX93_RS18555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKX93_RS18560	COG0444	Belongs to the ABC transporter superfamily
BKX93_RS18565	COG4608	Belongs to the ABC transporter superfamily
BKX93_RS18575	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BKX93_RS18585	COG0786	glutamate:sodium symporter activity
BKX93_RS18590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKX93_RS18630	COG4191	Histidine kinase
BKX93_RS18635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKX93_RS18640	COG0494	nUDIX hydrolase
BKX93_RS18675	COG0583	DNA-binding transcription factor activity
BKX93_RS18695	COG0114	fumarate hydratase activity
BKX93_RS18700	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BKX93_RS18705	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BKX93_RS18710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BKX93_RS18725	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BKX93_RS18735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BKX93_RS18740	COG0302	gtp cyclohydrolase
BKX93_RS18745	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BKX93_RS18750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKX93_RS18755	COG0583	DNA-binding transcription factor activity
BKX93_RS18775	COG2814	Major facilitator Superfamily
BKX93_RS18790	COG1012	belongs to the aldehyde dehydrogenase family
BKX93_RS18790	COG1454	alcohol dehydrogenase
BKX93_RS18795	COG1113	amino acid transport
BKX93_RS18805	COG0667	Aldo Keto reductase
BKX93_RS18825	COG0740	serine-type endopeptidase activity
BKX93_RS18830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BKX93_RS18835	COG5001	Diguanylate cyclase
BKX93_RS18835	COG3300	MHYT domain
BKX93_RS18840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKX93_RS18845	COG0583	DNA-binding transcription factor activity
BKX93_RS18855	COG1346	cytolysis
BKX93_RS18860	COG0789	Transcriptional regulator
BKX93_RS18875	COG1607	acyl-coa hydrolase
BKX93_RS18885	COG0564	pseudouridine synthase activity
BKX93_RS18900	COG0463	Glycosyl transferase, family 2
BKX93_RS18905	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKX93_RS18910	COG3104	oligopeptide transport
BKX93_RS18915	COG3033	Beta-eliminating lyase
BKX93_RS18930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BKX93_RS18950	COG2010	Cytochrome c
BKX93_RS18965	COG3278	Belongs to the heme-copper respiratory oxidase family
BKX93_RS18975	COG0308	aminopeptidase N
BKX93_RS18980	COG0071	Belongs to the small heat shock protein (HSP20) family
BKX93_RS18990	COG2814	Major facilitator Superfamily
BKX93_RS19000	COG0251	oxidation-reduction process
BKX93_RS19010	COG4302	ethanolamine ammonia-lyase activity
BKX93_RS19020	COG0531	amino acid
BKX93_RS19025	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BKX93_RS19035	COG3437	response regulator, receiver
BKX93_RS19040	COG2205	protein histidine kinase activity
BKX93_RS19040	COG3437	response regulator, receiver
BKX93_RS19040	COG3850	Histidine kinase
BKX93_RS19040	COG4999	Histidine kinase
BKX93_RS19065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BKX93_RS19090	COG2801	Transposase and inactivated derivatives
BKX93_RS19105	COG1301	dicarboxylic acid transport
BKX93_RS19120	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BKX93_RS19125	COG0489	protein tyrosine kinase activity
BKX93_RS19135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKX93_RS19135	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKX93_RS19160	COG1278	Cold shock
BKX93_RS19170	COG3022	response to hydroperoxide
BKX93_RS19175	COG1490	D-aminoacyl-tRNA deacylase activity
BKX93_RS19180	COG1289	transmembrane transporter activity
BKX93_RS19185	COG0741	lytic transglycosylase activity
BKX93_RS19185	COG1388	LysM domain
BKX93_RS19190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKX93_RS19195	COG2226	methyltransferase
BKX93_RS19200	COG0328	RNA-DNA hybrid ribonuclease activity
BKX93_RS19210	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BKX93_RS19215	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BKX93_RS19220	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BKX93_RS19225	COG0704	Plays a role in the regulation of phosphate uptake
BKX93_RS19230	COG0248	Ppx GppA phosphatase
BKX93_RS19235	COG0598	Magnesium transport protein CorA
BKX93_RS19245	COG1335	isochorismatase
BKX93_RS19250	COG2217	Heavy metal translocating P-type atpase
BKX93_RS19255	COG2608	mercury ion transmembrane transporter activity
BKX93_RS19280	COG0765	amino acid transport
BKX93_RS19285	COG0765	amino acid transport
BKX93_RS19290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKX93_RS19295	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BKX93_RS19300	COG0129	dihydroxy-acid dehydratase activity
BKX93_RS19310	COG2076	Multidrug Resistance protein
BKX93_RS19315	COG1196	nuclear chromosome segregation
BKX93_RS19325	COG0583	DNA-binding transcription factor activity
BKX93_RS19330	COG1741	Belongs to the pirin family
BKX93_RS19335	COG1335	isochorismatase
BKX93_RS19340	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BKX93_RS19345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKX93_RS19350	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKX93_RS19360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKX93_RS19365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKX93_RS19365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKX93_RS19375	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BKX93_RS19385	COG3539	Fimbrial protein
BKX93_RS19390	COG3121	Chaperone
BKX93_RS19440	COG0322	excinuclease ABC activity
BKX93_RS19445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BKX93_RS19480	COG3023	N-Acetylmuramoyl-L-alanine amidase
BKX93_RS19515	COG3773	Cell wall hydrolase
BKX93_RS19515	COG3409	Peptidoglycan-binding domain 1 protein
BKX93_RS19530	COG0326	Molecular chaperone. Has ATPase activity
BKX93_RS19580	COG1968	undecaprenyl-diphosphatase activity
BKX93_RS19590	COG2925	Exonuclease
BKX93_RS19595	COG1024	Enoyl-CoA hydratase
BKX93_RS19605	COG5001	Diguanylate cyclase
BKX93_RS19605	COG3706	GGDEF domain
BKX93_RS19605	COG2203	Gaf domain
BKX93_RS19605	COG4251	negative regulation of phosphorylation
BKX93_RS19610	COG3842	ATPase activity
BKX93_RS19615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKX93_RS19635	COG0586	Pfam SNARE associated Golgi protein
BKX93_RS19640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKX93_RS19645	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKX93_RS19650	COG1862	Preprotein translocase
BKX93_RS19655	COG0343	queuine tRNA-ribosyltransferase activity
BKX93_RS19665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKX93_RS19670	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BKX93_RS19675	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BKX93_RS19680	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BKX93_RS19685	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BKX93_RS19690	COG0072	phenylalanine-tRNA ligase activity
BKX93_RS19690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKX93_RS19695	COG0776	regulation of translation
BKX93_RS19725	COG2801	Transposase and inactivated derivatives
BKX93_RS19745	COG2119	membrane
BKX93_RS19750	COG1970	mechanosensitive ion channel activity
BKX93_RS19790	COG2866	Carboxypeptidase
BKX93_RS19815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKX93_RS19820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKX93_RS19835	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BKX93_RS19840	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BKX93_RS19845	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BKX93_RS19895	COG1857	crispr-associated protein
BKX93_RS19910	COG1518	maintenance of DNA repeat elements
BKX93_RS19915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BKX93_RS19950	COG1940	carbohydrate kinase activity
BKX93_RS19965	COG1082	Xylose isomerase domain protein TIM barrel
BKX93_RS19970	COG2814	Major facilitator Superfamily
BKX93_RS19990	COG0789	Transcriptional regulator
BKX93_RS19995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKX93_RS20010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKX93_RS20020	COG0494	nUDIX hydrolase
BKX93_RS20025	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BKX93_RS20060	COG0673	inositol 2-dehydrogenase activity
BKX93_RS20065	COG1760	l-serine dehydratase
BKX93_RS20070	COG0814	amino acid
BKX93_RS20075	COG2116	formate transmembrane transporter activity
BKX93_RS20085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BKX93_RS20090	COG3142	Participates in the control of copper homeostasis
BKX93_RS20120	COG2972	Histidine kinase
BKX93_RS20130	COG0488	(ABC) transporter
BKX93_RS20135	COG5342	invasion associated locus B
BKX93_RS20265	COG0174	glutamine synthetase
BKX93_RS20270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKX93_RS20285	COG2095	MarC family integral membrane protein
BKX93_RS20290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKX93_RS20295	COG1393	Belongs to the ArsC family
BKX93_RS20305	COG0318	PFAM AMP-dependent synthetase and ligase
BKX93_RS20310	COG0779	Required for maturation of 30S ribosomal subunits
BKX93_RS20315	COG0195	Participates in both transcription termination and antitermination
BKX93_RS20315	COG2251	uridine kinase activity
BKX93_RS20320	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BKX93_RS20325	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BKX93_RS20330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BKX93_RS20335	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BKX93_RS20340	COG1185	polyribonucleotide nucleotidyltransferase activity
BKX93_RS20475	COG0741	lytic transglycosylase activity
BKX93_RS20475	COG1196	nuclear chromosome segregation
BKX93_RS20475	COG0739	heme binding
BKX93_RS20485	COG2197	response regulator
BKX93_RS20560	COG1028	Short-chain dehydrogenase reductase Sdr
BKX93_RS20565	COG3433	isochorismatase activity
BKX93_RS20565	COG1535	isochorismatase
BKX93_RS20570	COG1021	2,3-dihydroxybenzoate-AMP ligase
BKX93_RS20580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKX93_RS20585	COG1120	ATPase activity
BKX93_RS20590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKX93_RS20605	COG4771	TonB-dependent receptor
BKX93_RS20615	COG1047	Peptidyl-prolyl cis-trans
BKX93_RS20630	COG3842	ATPase activity
BKX93_RS20645	COG2837	iron assimilation
BKX93_RS20655	COG3659	wide pore channel activity
BKX93_RS20660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKX93_RS20675	COG1012	belongs to the aldehyde dehydrogenase family
BKX93_RS20680	COG3724	N-succinylarginine dihydrolase activity
BKX93_RS20685	COG0559	Belongs to the binding-protein-dependent transport system permease family
BKX93_RS20715	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BKX93_RS20725	COG2814	Major facilitator Superfamily
BKX93_RS20745	COG1785	Belongs to the alkaline phosphatase family
BKX93_RS20750	COG3437	response regulator, receiver
BKX93_RS20750	COG2770	Histidine kinase
BKX93_RS20755	COG1643	Atp-dependent helicase
BKX93_RS20760	COG0523	cobalamin synthesis protein
BKX93_RS20775	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BKX93_RS20780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKX93_RS20790	COG4585	Histidine kinase
BKX93_RS20795	COG4585	Histidine kinase
BKX93_RS20800	COG2197	response regulator
BKX93_RS20815	COG1349	DNA-binding transcription factor activity
BKX93_RS20820	COG0561	phosphatase activity
BKX93_RS20835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BKX93_RS20850	COG0697	spore germination
BKX93_RS20920	COG1024	Enoyl-CoA hydratase
BKX93_RS20930	COG2755	lipolytic protein G-D-S-L family
BKX93_RS20935	COG0778	Nitroreductase
BKX93_RS20940	COG1797	cobyrinic acid a,c-diamide synthase activity
BKX93_RS20950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKX93_RS20960	COG1120	ATPase activity
BKX93_RS20990	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BKX93_RS20995	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BKX93_RS21020	COG3411	Ferredoxin
BKX93_RS21025	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BKX93_RS21035	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BKX93_RS21040	COG1492	cobalamin metabolic process
BKX93_RS21060	COG5001	Diguanylate cyclase
BKX93_RS21060	COG3300	MHYT domain
BKX93_RS21065	COG5002	protein histidine kinase activity
BKX93_RS21065	COG2205	protein histidine kinase activity
BKX93_RS21065	COG0784	Response regulator, receiver
BKX93_RS21070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BKX93_RS21075	COG2205	protein histidine kinase activity
BKX93_RS21075	COG0784	Response regulator, receiver
BKX93_RS21075	COG5002	protein histidine kinase activity
BKX93_RS21080	COG0840	transmembrane signaling receptor activity
BKX93_RS21085	COG0840	transmembrane signaling receptor activity
BKX93_RS21100	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BKX93_RS21135	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BKX93_RS21140	COG0534	Mate efflux family protein
BKX93_RS21150	COG2271	Major facilitator Superfamily
BKX93_RS21155	COG3424	synthase
BKX93_RS21180	COG0745	RESPONSE REGULATOR receiver
BKX93_RS21185	COG2205	protein histidine kinase activity
BKX93_RS21190	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BKX93_RS21195	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BKX93_RS21200	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BKX93_RS21220	COG0730	response to heat
BKX93_RS21235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKX93_RS21245	COG2137	regulation of response to DNA damage stimulus
BKX93_RS21250	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BKX93_RS21255	COG1420	regulation of RNA biosynthetic process
BKX93_RS21260	COG2951	lytic endotransglycosylase activity
BKX93_RS21265	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BKX93_RS21270	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BKX93_RS21280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BKX93_RS21285	COG2226	methyltransferase
BKX93_RS21290	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BKX93_RS21300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKX93_RS21300	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BKX93_RS21320	COG1846	Transcriptional regulator
BKX93_RS21340	COG0784	Response regulator, receiver
BKX93_RS21340	COG2205	protein histidine kinase activity
BKX93_RS21340	COG5002	protein histidine kinase activity
BKX93_RS21345	COG0243	molybdopterin cofactor binding
BKX93_RS21355	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BKX93_RS21360	COG0746	molybdenum cofactor guanylyltransferase activity
BKX93_RS21365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKX93_RS21370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKX93_RS21375	COG1538	Outer membrane efflux protein
BKX93_RS21390	COG0583	DNA-binding transcription factor activity
BKX93_RS21395	COG0617	tRNA 3'-terminal CCA addition
BKX93_RS21410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BKX93_RS21415	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BKX93_RS21420	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BKX93_RS21435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BKX93_RS21445	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BKX93_RS21450	COG0443	Heat shock 70 kDa protein
BKX93_RS21455	COG3239	Fatty acid desaturase
BKX93_RS21460	COG0484	heat shock protein binding
BKX93_RS21485	COG1063	alcohol dehydrogenase
BKX93_RS21490	COG0840	transmembrane signaling receptor activity
BKX93_RS21495	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BKX93_RS21500	COG0752	glycyl-tRNA synthetase alpha subunit
BKX93_RS21515	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BKX93_RS21540	COG1966	Carbon starvation protein
BKX93_RS21550	COG3279	Response regulator of the LytR AlgR family
BKX93_RS21555	COG3275	phosphorelay sensor kinase activity
BKX93_RS21560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKX93_RS21575	COG0733	neurotransmitter:sodium symporter activity
BKX93_RS21615	COG0840	transmembrane signaling receptor activity
BKX93_RS21640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKX93_RS21645	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKX93_RS21665	COG0252	asparaginase activity
BKX93_RS21685	COG0613	PHP domain protein
BKX93_RS21690	COG0009	L-threonylcarbamoyladenylate synthase
BKX93_RS21700	COG1994	Peptidase M50
BKX93_RS21705	COG0180	Tryptophanyl-tRNA synthetase
BKX93_RS21735	COG1558	bacterial-type flagellum-dependent cell motility
BKX93_RS21755	COG4786	Flagellar basal body rod
BKX93_RS21760	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BKX93_RS21765	COG1706	bacterial-type flagellum-dependent cell motility
BKX93_RS21775	COG1256	bacterial-type flagellum assembly
BKX93_RS21795	COG0367	asparagine synthase
BKX93_RS21800	COG1522	sequence-specific DNA binding
BKX93_RS21845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKX93_RS21880	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BKX93_RS21895	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BKX93_RS21900	COG1032	radical SAM domain protein
BKX93_RS21920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKX93_RS21925	COG0737	Belongs to the 5'-nucleotidase family
BKX93_RS21935	COG0205	6-phosphofructokinase activity
BKX93_RS21940	COG0215	cysteine-tRNA ligase activity
BKX93_RS21945	COG0254	rRNA binding
BKX93_RS21955	COG0583	DNA-binding transcription factor activity
BKX93_RS21985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKX93_RS22005	COG4770	biotin carboxylase activity
BKX93_RS22010	COG1024	Enoyl-CoA hydratase
BKX93_RS22015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKX93_RS22025	COG1960	acyl-CoA dehydrogenase activity
BKX93_RS22030	COG1671	Belongs to the UPF0178 family
BKX93_RS22035	COG2223	nitrite transmembrane transporter activity
BKX93_RS22040	COG3279	Response regulator of the LytR AlgR family
BKX93_RS22045	COG3275	phosphorelay sensor kinase activity
BKX93_RS22060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKX93_RS22060	COG1017	nitric oxide dioxygenase activity
BKX93_RS22065	COG0625	glutathione transferase activity
BKX93_RS22070	COG1846	Transcriptional regulator
BKX93_RS22075	COG0697	spore germination
BKX93_RS22110	COG2226	methyltransferase
BKX93_RS22120	COG1960	acyl-CoA dehydrogenase activity
BKX93_RS22125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKX93_RS22130	COG0318	PFAM AMP-dependent synthetase and ligase
BKX93_RS22170	COG0318	PFAM AMP-dependent synthetase and ligase
BKX93_RS22175	COG0456	acetyltransferase
BKX93_RS22180	COG0789	Transcriptional regulator
BKX93_RS22200	COG3012	SEC-C Motif Domain Protein
BKX93_RS22200	COG3318	Belongs to the UPF0149 family
BKX93_RS22220	COG1960	acyl-CoA dehydrogenase activity
BKX93_RS22230	COG0494	nUDIX hydrolase
BKX93_RS22240	COG2766	serine protein kinase
BKX93_RS22245	COG2718	Belongs to the UPF0229 family
BKX93_RS22250	COG2719	SpoVR family
BKX93_RS22265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKX93_RS22270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BKX93_RS22275	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKX93_RS22285	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BKX93_RS22290	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BKX93_RS22300	COG0167	dihydroorotate dehydrogenase activity
BKX93_RS22315	COG0616	signal peptide processing
BKX93_RS22315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BKX93_RS22335	COG1530	ribonuclease E activity
BKX93_RS22350	COG0671	phosphoesterase, PA-phosphatase related
BKX93_RS22360	COG3681	Belongs to the UPF0597 family
BKX93_RS22365	COG2207	Transcriptional regulator
BKX93_RS22375	COG0583	DNA-binding transcription factor activity
BKX93_RS22380	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BKX93_RS22385	COG4208	sulfate ABC transporter
BKX93_RS22390	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BKX93_RS22395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BKX93_RS22420	COG1309	transcriptional regulator
BKX93_RS22435	COG3454	Phosphonate metabolism
BKX93_RS22440	COG4778	phosphonate C-P lyase system protein PhnL
BKX93_RS22445	COG4107	phosphonate C-P lyase system protein PhnK
BKX93_RS22450	COG3627	carbon phosphorus lyase activity
BKX93_RS22455	COG3626	phosphonate metabolism
BKX93_RS22460	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BKX93_RS22465	COG3624	Phosphonate C-P lyase system protein PhnG
BKX93_RS22470	COG2188	Transcriptional regulator
BKX93_RS22475	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BKX93_RS22480	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BKX93_RS22500	COG1840	ABC-type Fe3 transport system, periplasmic component
BKX93_RS22505	COG3842	ATPase activity
BKX93_RS22535	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BKX93_RS22545	COG0583	DNA-binding transcription factor activity
BKX93_RS22555	COG1473	amidohydrolase
BKX93_RS22570	COG1522	sequence-specific DNA binding
BKX93_RS22585	COG3938	Belongs to the proline racemase family
BKX93_RS22590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKX93_RS22600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKX93_RS22625	COG2814	Major facilitator Superfamily
BKX93_RS22650	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BKX93_RS22660	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BKX93_RS22665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKX93_RS22715	COG3842	ATPase activity
BKX93_RS22720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BKX93_RS22725	COG0840	transmembrane signaling receptor activity
BKX93_RS22735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKX93_RS22740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BKX93_RS22755	COG1741	Belongs to the pirin family
BKX93_RS22765	COG0583	DNA-binding transcription factor activity
BKX93_RS22770	COG1802	Transcriptional regulator
BKX93_RS22800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BKX93_RS22805	COG0788	formyltetrahydrofolate deformylase activity
BKX93_RS22820	COG1968	undecaprenyl-diphosphatase activity
BKX93_RS22830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BKX93_RS22835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKX93_RS22840	COG1376	ErfK ybiS ycfS ynhG family protein
BKX93_RS22895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BKX93_RS22920	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BKX93_RS22985	COG2207	Transcriptional regulator
BKX93_RS23025	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKX93_RS23075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKX93_RS23085	COG5001	Diguanylate cyclase
BKX93_RS23085	COG1716	ATPase activity
BKX93_RS23095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKX93_RS23105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKX93_RS23120	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKX93_RS23130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKX93_RS23130	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BKX93_RS23140	COG0542	response to heat
BKX93_RS23145	COG2818	Glycosylase
BKX93_RS23150	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BKX93_RS23155	COG2207	Transcriptional regulator
BKX93_RS23155	COG4753	response regulator
BKX93_RS23160	COG0745	RESPONSE REGULATOR receiver
BKX93_RS23165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKX93_RS23165	COG2205	protein histidine kinase activity
BKX93_RS23170	COG2833	Protein of unknown function (DUF455)
BKX93_RS23185	COG0826	peptidase U32
BKX93_RS23195	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKX93_RS23200	COG1177	transmembrane transport
BKX93_RS23210	COG0018	arginyl-trna synthetase