locus-tag	class	description
EGY05_RS00005	COG0217	transcriptional regulatory protein
EGY05_RS00050	COG0714	Associated with various cellular activities
EGY05_RS00080	COG0527	aspartate kinase activity
EGY05_RS00080	COG0460	homoserine dehydrogenase
EGY05_RS00090	COG1410	methionine synthase
EGY05_RS00090	COG0646	methionine synthase
EGY05_RS00110	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EGY05_RS00125	COG0302	gtp cyclohydrolase
EGY05_RS00135	COG0215	cysteine-tRNA ligase activity
EGY05_RS00200	COG1640	4-alpha-glucanotransferase
EGY05_RS00215	COG1528	Iron-storage protein
EGY05_RS00225	COG1074	ATP-dependent DNA helicase activity
EGY05_RS00265	COG0438	transferase activity, transferring glycosyl groups
EGY05_RS00270	COG1472	Belongs to the glycosyl hydrolase 3 family
EGY05_RS00280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGY05_RS00295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGY05_RS00310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGY05_RS00320	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EGY05_RS00345	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS00370	COG1404	Belongs to the peptidase S8 family
EGY05_RS00425	COG2197	response regulator
EGY05_RS00430	COG4585	Histidine kinase
EGY05_RS00450	COG0542	response to heat
EGY05_RS00465	COG1309	transcriptional regulator
EGY05_RS00470	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EGY05_RS00475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGY05_RS00480	COG3396	Phenylacetate-CoA oxygenase
EGY05_RS00485	COG3460	Phenylacetate-CoA oxygenase
EGY05_RS00500	COG2151	metal-sulfur cluster biosynthetic enzyme
EGY05_RS00510	COG1024	Enoyl-CoA hydratase
EGY05_RS00515	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGY05_RS00535	COG0183	Belongs to the thiolase family
EGY05_RS00550	COG2030	dehydratase
EGY05_RS00550	COG1012	belongs to the aldehyde dehydrogenase family
EGY05_RS00605	COG1408	metallophosphoesterase
EGY05_RS00640	COG1404	Belongs to the peptidase S8 family
EGY05_RS00640	COG4935	Belongs to the peptidase S8 family
EGY05_RS00650	COG1490	D-aminoacyl-tRNA deacylase activity
EGY05_RS00660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGY05_RS00670	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EGY05_RS00800	COG0280	phosphate acetyltransferase
EGY05_RS00800	COG0281	malic enzyme
EGY05_RS00805	COG0632	four-way junction helicase activity
EGY05_RS00815	COG0509	glycine decarboxylation via glycine cleavage system
EGY05_RS00850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGY05_RS00870	COG0322	excinuclease ABC activity
EGY05_RS00880	COG2986	histidine ammonia-lyase
EGY05_RS00890	COG1404	Belongs to the peptidase S8 family
EGY05_RS00895	COG3384	dioxygenase
EGY05_RS00900	COG2353	YceI-like domain
EGY05_RS00905	COG0823	Involved in the tonB-independent uptake of proteins
EGY05_RS00905	COG1506	peptidase
EGY05_RS00930	COG0419	ATPase involved in DNA repair
EGY05_RS00935	COG0420	3'-5' exonuclease activity
EGY05_RS00940	COG4628	conserved protein (DUF2132)
EGY05_RS00955	COG3012	SEC-C Motif Domain Protein
EGY05_RS00960	COG0339	signal peptide processing
EGY05_RS00990	COG1704	LemA family
EGY05_RS00995	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EGY05_RS01010	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EGY05_RS01020	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGY05_RS01030	COG0564	pseudouridine synthase activity
EGY05_RS01040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGY05_RS01055	COG1733	regulation of RNA biosynthetic process
EGY05_RS01090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY05_RS01105	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EGY05_RS01110	COG0242	peptide deformylase activity
EGY05_RS01120	COG3956	TIGRFAM MazG family protein
EGY05_RS01200	COG1007	ATP synthesis coupled electron transport
EGY05_RS01205	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGY05_RS01210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGY05_RS01215	COG0713	ATP synthesis coupled electron transport
EGY05_RS01220	COG0839	Belongs to the complex I subunit 6 family
EGY05_RS01225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGY05_RS01230	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EGY05_RS01235	COG1034	ATP synthesis coupled electron transport
EGY05_RS01245	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EGY05_RS01250	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EGY05_RS01255	COG0649	NAD binding
EGY05_RS01260	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGY05_RS01265	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGY05_RS01270	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGY05_RS01285	COG1739	Uncharacterized protein family UPF0029
EGY05_RS01295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGY05_RS01295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGY05_RS01305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGY05_RS01310	COG2356	endonuclease I
EGY05_RS01320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EGY05_RS01325	COG0346	lactoylglutathione lyase activity
EGY05_RS01350	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EGY05_RS01400	COG0025	NhaP-type Na H and K H
EGY05_RS01465	COG0084	hydrolase, TatD family'
EGY05_RS01470	COG0813	purine-nucleoside phosphorylase activity
EGY05_RS01475	COG0346	lactoylglutathione lyase activity
EGY05_RS01490	COG0714	Associated with various cellular activities
EGY05_RS01620	COG2267	carboxylic ester hydrolase activity
EGY05_RS01705	COG0659	secondary active sulfate transmembrane transporter activity
EGY05_RS01710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EGY05_RS01725	COG2310	stress, protein
EGY05_RS01730	COG3853	Toxic anion resistance protein (TelA)
EGY05_RS01775	COG1959	2 iron, 2 sulfur cluster binding
EGY05_RS01780	COG0702	epimerase
EGY05_RS01790	COG0739	heme binding
EGY05_RS01795	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EGY05_RS01800	COG0579	oxidoreductase
EGY05_RS01850	COG0737	Belongs to the 5'-nucleotidase family
EGY05_RS01855	COG0737	Belongs to the 5'-nucleotidase family
EGY05_RS01860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGY05_RS01880	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGY05_RS01885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGY05_RS01890	COG3104	oligopeptide transport
EGY05_RS01900	COG3104	oligopeptide transport
EGY05_RS01905	COG3104	oligopeptide transport
EGY05_RS01915	COG0823	Involved in the tonB-independent uptake of proteins
EGY05_RS01915	COG1506	peptidase
EGY05_RS01950	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGY05_RS01955	COG0069	glutamate synthase activity
EGY05_RS01965	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGY05_RS01970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EGY05_RS01990	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EGY05_RS01995	COG0297	glycogen (starch) synthase activity
EGY05_RS02005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGY05_RS02010	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EGY05_RS02035	COG4095	Psort location CytoplasmicMembrane, score
EGY05_RS02065	COG1538	Outer membrane efflux protein
EGY05_RS02130	COG0024	Methionine aminopeptidase
EGY05_RS02140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGY05_RS02195	COG0252	asparaginase activity
EGY05_RS02215	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EGY05_RS02225	COG1522	sequence-specific DNA binding
EGY05_RS02300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EGY05_RS02320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGY05_RS02325	COG2388	GCN5-related N-acetyl-transferase
EGY05_RS02345	COG0431	NADPH-dependent FMN reductase
EGY05_RS02350	COG1741	Belongs to the pirin family
EGY05_RS02365	COG0477	Major facilitator Superfamily
EGY05_RS02375	COG0367	asparagine synthase
EGY05_RS02385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGY05_RS02385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EGY05_RS02390	COG2824	Alkylphosphonate utilization operon protein PhnA
EGY05_RS02395	COG3842	ATPase activity
EGY05_RS02405	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EGY05_RS02410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY05_RS02420	COG0492	ferredoxin-NADP+ reductase activity
EGY05_RS02435	COG1611	Belongs to the LOG family
EGY05_RS02445	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGY05_RS02460	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EGY05_RS02475	COG0612	Peptidase, M16
EGY05_RS02480	COG0612	Peptidase, M16
EGY05_RS02490	COG4771	TonB-dependent receptor
EGY05_RS02495	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EGY05_RS02500	COG0351	phosphomethylpyrimidine kinase
EGY05_RS02500	COG0352	thiamine-phosphate diphosphorylase activity
EGY05_RS02505	COG0352	thiamine-phosphate diphosphorylase activity
EGY05_RS02510	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EGY05_RS02515	COG1966	Carbon starvation protein
EGY05_RS02570	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EGY05_RS02580	COG0427	acetyl-CoA hydrolase
EGY05_RS02585	COG0427	acetyl-CoA hydrolase
EGY05_RS02590	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EGY05_RS02595	COG4771	TonB-dependent receptor
EGY05_RS02615	COG1733	regulation of RNA biosynthetic process
EGY05_RS02620	COG2113	Glycine betaine
EGY05_RS02625	COG4176	ABC-type proline glycine betaine transport system permease component
EGY05_RS02630	COG3448	diguanylate cyclase activity
EGY05_RS02630	COG4175	Glycine betaine
EGY05_RS02650	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGY05_RS02665	COG0667	Aldo Keto reductase
EGY05_RS02680	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGY05_RS02690	COG0583	DNA-binding transcription factor activity
EGY05_RS02695	COG0456	acetyltransferase
EGY05_RS02700	COG0519	Catalyzes the synthesis of GMP from XMP
EGY05_RS02705	COG0656	L-ascorbic acid biosynthetic process
EGY05_RS02715	COG2070	2-Nitropropane dioxygenase
EGY05_RS02725	COG1733	regulation of RNA biosynthetic process
EGY05_RS02740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGY05_RS02765	COG1530	ribonuclease E activity
EGY05_RS02770	COG0776	regulation of translation
EGY05_RS02775	COG2197	response regulator
EGY05_RS02805	COG3501	Rhs element vgr protein
EGY05_RS02835	COG0542	response to heat
EGY05_RS02855	COG3501	Rhs element vgr protein
EGY05_RS02885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGY05_RS02885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGY05_RS02915	COG4717	serine-type aminopeptidase activity
EGY05_RS02930	COG0612	Peptidase, M16
EGY05_RS02960	COG2204	response regulator
EGY05_RS02970	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EGY05_RS02980	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EGY05_RS02990	COG2205	protein histidine kinase activity
EGY05_RS03020	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EGY05_RS03030	COG0584	glycerophosphoryl diester phosphodiesterase
EGY05_RS03035	COG4771	TonB-dependent receptor
EGY05_RS03050	COG0300	oxidoreductase activity
EGY05_RS03055	COG2264	protein methyltransferase activity
EGY05_RS03085	COG1525	nuclease
EGY05_RS03100	COG2312	Erythromycin esterase
EGY05_RS03145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGY05_RS03170	COG0596	Alpha beta hydrolase
EGY05_RS03185	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EGY05_RS03205	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGY05_RS03215	COG0463	Glycosyl transferase, family 2
EGY05_RS03250	COG0306	phosphate transporter
EGY05_RS03270	COG0084	hydrolase, TatD family'
EGY05_RS03280	COG0513	Belongs to the DEAD box helicase family
EGY05_RS03290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EGY05_RS03295	COG0563	adenylate kinase activity
EGY05_RS03300	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EGY05_RS03305	COG0488	(ABC) transporter
EGY05_RS03325	COG2378	regulation of single-species biofilm formation
EGY05_RS03330	COG0563	adenylate kinase activity
EGY05_RS03340	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EGY05_RS03355	COG1192	Involved in chromosome partitioning
EGY05_RS03360	COG1475	DNA binding
EGY05_RS03370	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EGY05_RS03375	COG0681	Belongs to the peptidase S26 family
EGY05_RS03400	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EGY05_RS03405	COG0277	FAD linked oxidase domain protein
EGY05_RS03425	COG1104	cysteine desulfurase activity
EGY05_RS03455	COG0583	DNA-binding transcription factor activity
EGY05_RS03460	COG2986	histidine ammonia-lyase
EGY05_RS03465	COG1228	amidohydrolase
EGY05_RS03545	COG2197	response regulator
EGY05_RS03560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGY05_RS03570	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGY05_RS03575	COG1917	Cupin 2, conserved barrel domain protein
EGY05_RS03575	COG2207	Transcriptional regulator
EGY05_RS03580	COG2814	Major facilitator Superfamily
EGY05_RS03595	COG0723	plastoquinol--plastocyanin reductase activity
EGY05_RS03595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGY05_RS03610	COG3275	phosphorelay sensor kinase activity
EGY05_RS03615	COG3279	Response regulator of the LytR AlgR family
EGY05_RS03630	COG1546	Belongs to the CinA family
EGY05_RS03630	COG1058	Belongs to the CinA family
EGY05_RS03640	COG3590	peptidase
EGY05_RS03645	COG3590	peptidase
EGY05_RS03680	COG0351	phosphomethylpyrimidine kinase
EGY05_RS03685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGY05_RS03695	COG2267	carboxylic ester hydrolase activity
EGY05_RS03725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGY05_RS03730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGY05_RS03765	COG1538	Outer membrane efflux protein
EGY05_RS03770	COG1278	Cold shock
EGY05_RS03780	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EGY05_RS03920	COG0321	lipoyl(octanoyl) transferase activity
EGY05_RS03920	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EGY05_RS03945	COG2239	Acts as a magnesium transporter
EGY05_RS03955	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EGY05_RS03975	COG1185	polyribonucleotide nucleotidyltransferase activity
EGY05_RS03995	COG1131	(ABC) transporter
EGY05_RS04000	COG3655	Transcriptional regulator
EGY05_RS04050	COG3541	Predicted nucleotidyltransferase
EGY05_RS04055	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EGY05_RS04060	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EGY05_RS04065	COG0406	alpha-ribazole phosphatase activity
EGY05_RS04105	COG0837	glucose binding
EGY05_RS04130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EGY05_RS04140	COG1760	l-serine dehydratase
EGY05_RS04145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY05_RS04160	COG0287	Prephenate dehydrogenase
EGY05_RS04190	COG0475	glutathione-regulated potassium exporter activity
EGY05_RS04200	COG3279	Response regulator of the LytR AlgR family
EGY05_RS04220	COG0802	atpase or kinase
EGY05_RS04230	COG0358	DNA primase activity
EGY05_RS04255	COG0149	triose-phosphate isomerase activity
EGY05_RS04285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGY05_RS04295	COG0129	dihydroxy-acid dehydratase activity
EGY05_RS04300	COG0028	Belongs to the TPP enzyme family
EGY05_RS04305	COG0440	acetolactate synthase activity
EGY05_RS04310	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EGY05_RS04315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGY05_RS04335	COG1858	cytochrome C peroxidase
EGY05_RS04345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EGY05_RS04350	COG1595	DNA-templated transcription, initiation
EGY05_RS04365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGY05_RS04365	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGY05_RS04390	COG1131	(ABC) transporter
EGY05_RS04395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGY05_RS04415	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EGY05_RS04420	COG0586	Pfam SNARE associated Golgi protein
EGY05_RS04430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY05_RS04440	COG2354	Protein conserved in bacteria
EGY05_RS04450	COG0484	heat shock protein binding
EGY05_RS04455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EGY05_RS04460	COG1914	H( )-stimulated, divalent metal cation uptake system
EGY05_RS04470	COG0442	prolyl-tRNA aminoacylation
EGY05_RS04495	COG0116	Belongs to the methyltransferase superfamily
EGY05_RS04525	COG0626	cystathionine gamma-synthase activity
EGY05_RS04530	COG1522	sequence-specific DNA binding
EGY05_RS04540	COG3781	membrane
EGY05_RS04545	COG0022	dehydrogenase e1 component
EGY05_RS04550	COG0587	DNA-directed DNA polymerase activity
EGY05_RS04560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGY05_RS04570	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EGY05_RS04580	COG1022	Amp-dependent synthetase and ligase
EGY05_RS04585	COG1960	acyl-CoA dehydrogenase activity
EGY05_RS04600	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EGY05_RS04620	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EGY05_RS04625	COG1234	tRNA 3'-trailer cleavage
EGY05_RS04655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGY05_RS04660	COG2177	Part of the ABC transporter FtsEX involved in
EGY05_RS04670	COG1968	undecaprenyl-diphosphatase activity
EGY05_RS04675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EGY05_RS04685	COG1187	pseudouridine synthase activity
EGY05_RS04735	COG0513	Belongs to the DEAD box helicase family
EGY05_RS04740	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EGY05_RS04745	COG3421	Type III restriction
EGY05_RS04750	COG0539	negative regulation of cytoplasmic translation
EGY05_RS04750	COG2183	response to ionizing radiation
EGY05_RS04795	COG2814	Major facilitator Superfamily
EGY05_RS04810	COG0335	large ribosomal subunit rRNA binding
EGY05_RS04825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EGY05_RS04830	COG1132	(ABC) transporter
EGY05_RS04845	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EGY05_RS04855	COG0730	response to heat
EGY05_RS04860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY05_RS04865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGY05_RS04865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGY05_RS04880	COG1538	Outer membrane efflux protein
EGY05_RS04885	COG1566	PFAM secretion protein HlyD family protein
EGY05_RS04900	COG1446	asparaginase
EGY05_RS04910	COG3142	Participates in the control of copper homeostasis
EGY05_RS04915	COG3250	beta-galactosidase activity
EGY05_RS04920	COG0679	Auxin Efflux Carrier
EGY05_RS04925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGY05_RS04945	COG0156	8-amino-7-oxononanoate synthase activity
EGY05_RS04955	COG1981	membrane
EGY05_RS04990	COG1959	2 iron, 2 sulfur cluster binding
EGY05_RS05025	COG4558	Periplasmic binding protein
EGY05_RS05030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGY05_RS05040	COG2226	methyltransferase
EGY05_RS05045	COG3720	iron ion transport
EGY05_RS05055	COG0242	peptide deformylase activity
EGY05_RS05060	COG1764	response to oxidative stress
EGY05_RS05065	COG1846	Transcriptional regulator
EGY05_RS05070	COG0778	Nitroreductase
EGY05_RS05075	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS05090	COG0321	lipoyl(octanoyl) transferase activity
EGY05_RS05095	COG0159	tryptophan synthase activity
EGY05_RS05100	COG0133	tryptophan synthase activity
EGY05_RS05115	COG0135	phosphoribosylanthranilate isomerase activity
EGY05_RS05120	COG0134	indole-3-glycerol-phosphate synthase activity
EGY05_RS05125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGY05_RS05130	COG0512	Glutamine amidotransferase of anthranilate synthase
EGY05_RS05135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGY05_RS05160	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EGY05_RS05165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EGY05_RS05180	COG1271	oxidase subunit
EGY05_RS05185	COG0187	DNA topoisomerase II activity
EGY05_RS05225	COG1301	dicarboxylic acid transport
EGY05_RS05230	COG0405	Gamma-glutamyltransferase
EGY05_RS05235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGY05_RS05245	COG1408	metallophosphoesterase
EGY05_RS05250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGY05_RS05260	COG2226	methyltransferase
EGY05_RS05280	COG1418	mRNA catabolic process
EGY05_RS05285	COG0477	Major facilitator Superfamily
EGY05_RS05300	COG2855	membrane
EGY05_RS05310	COG0038	chloride channel
EGY05_RS05320	COG1607	acyl-coa hydrolase
EGY05_RS05340	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EGY05_RS05350	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EGY05_RS05360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGY05_RS05365	COG1970	mechanosensitive ion channel activity
EGY05_RS05370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGY05_RS05370	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EGY05_RS05375	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EGY05_RS05380	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EGY05_RS05385	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGY05_RS05405	COG0077	Prephenate dehydratase
EGY05_RS05415	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EGY05_RS05420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGY05_RS05430	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGY05_RS05480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGY05_RS05480	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGY05_RS05485	COG4206	TonB-dependent receptor
EGY05_RS05485	COG1629	transport
EGY05_RS05490	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EGY05_RS05500	COG1082	Xylose isomerase domain protein TIM barrel
EGY05_RS05510	COG0366	Alpha amylase catalytic
EGY05_RS05525	COG1741	Belongs to the pirin family
EGY05_RS05535	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EGY05_RS05540	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGY05_RS05555	COG0151	Belongs to the GarS family
EGY05_RS05560	COG0519	Catalyzes the synthesis of GMP from XMP
EGY05_RS05560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGY05_RS05565	COG3153	acetyltransferase
EGY05_RS05565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGY05_RS05580	COG0513	Belongs to the DEAD box helicase family
EGY05_RS05600	COG1979	alcohol dehydrogenase
EGY05_RS05625	COG0242	peptide deformylase activity
EGY05_RS05660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGY05_RS05675	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGY05_RS05680	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EGY05_RS05695	COG0531	amino acid
EGY05_RS05705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGY05_RS05735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGY05_RS05740	COG0671	phosphoesterase, PA-phosphatase related
EGY05_RS05755	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EGY05_RS05760	COG1295	ribonuclease BN
EGY05_RS05765	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EGY05_RS05770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGY05_RS05780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGY05_RS05790	COG0745	RESPONSE REGULATOR receiver
EGY05_RS05795	COG5002	protein histidine kinase activity
EGY05_RS05835	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EGY05_RS05850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EGY05_RS05855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGY05_RS05860	COG0165	Argininosuccinate lyase
EGY05_RS05865	COG1522	sequence-specific DNA binding
EGY05_RS05870	COG0540	Belongs to the ATCase OTCase family
EGY05_RS05875	COG0505	Belongs to the CarA family
EGY05_RS05895	COG1864	DNA RNA non-specific endonuclease
EGY05_RS05895	COG3591	Belongs to the peptidase S1B family
EGY05_RS05940	COG3693	PFAM glycoside hydrolase, family 10
EGY05_RS05940	COG2382	esterase
EGY05_RS05970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGY05_RS05980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGY05_RS06005	COG1011	Hydrolase
EGY05_RS06020	COG0492	ferredoxin-NADP+ reductase activity
EGY05_RS06055	COG0629	single-stranded DNA binding
EGY05_RS06080	COG4771	TonB-dependent receptor
EGY05_RS06100	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGY05_RS06105	COG0210	DNA helicase
EGY05_RS06160	COG2205	protein histidine kinase activity
EGY05_RS06160	COG3850	Histidine kinase
EGY05_RS06160	COG4999	Histidine kinase
EGY05_RS06160	COG3437	response regulator, receiver
EGY05_RS06165	COG3685	Protein conserved in bacteria
EGY05_RS06185	COG3279	Response regulator of the LytR AlgR family
EGY05_RS06195	COG2267	carboxylic ester hydrolase activity
EGY05_RS06235	COG2205	protein histidine kinase activity
EGY05_RS06235	COG0784	Response regulator, receiver
EGY05_RS06275	COG2204	response regulator
EGY05_RS06285	COG1136	(ABC) transporter
EGY05_RS06285	COG0577	efflux transmembrane transporter activity
EGY05_RS06320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGY05_RS06335	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS06345	COG4977	sequence-specific DNA binding
EGY05_RS06345	COG1917	Cupin 2, conserved barrel domain protein
EGY05_RS06375	COG1846	Transcriptional regulator
EGY05_RS06425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGY05_RS06435	COG0492	ferredoxin-NADP+ reductase activity
EGY05_RS06440	COG0431	NADPH-dependent FMN reductase
EGY05_RS06450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGY05_RS06465	COG1595	DNA-templated transcription, initiation
EGY05_RS06520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGY05_RS06530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EGY05_RS06575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGY05_RS06600	COG1131	(ABC) transporter
EGY05_RS06605	COG1660	Displays ATPase and GTPase activities
EGY05_RS06635	COG2226	methyltransferase
EGY05_RS06720	COG3279	Response regulator of the LytR AlgR family
EGY05_RS06730	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EGY05_RS06740	COG2837	iron assimilation
EGY05_RS06750	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EGY05_RS06755	COG0314	molybdopterin synthase activity
EGY05_RS06780	COG3781	membrane
EGY05_RS06800	COG0746	molybdenum cofactor guanylyltransferase activity
EGY05_RS06800	COG0315	cyclic pyranopterin monophosphate synthase activity
EGY05_RS06810	COG0303	'Molybdopterin
EGY05_RS06820	COG2207	Transcriptional regulator
EGY05_RS06820	COG1917	Cupin 2, conserved barrel domain protein
EGY05_RS06825	COG0384	phenazine biosynthesis protein PhzF
EGY05_RS06850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY05_RS06875	COG2814	Major facilitator Superfamily
EGY05_RS06890	COG2197	response regulator
EGY05_RS06900	COG2207	Transcriptional regulator
EGY05_RS06905	COG0156	8-amino-7-oxononanoate synthase activity
EGY05_RS06915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGY05_RS06925	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EGY05_RS06925	COG1605	Chorismate mutase
EGY05_RS06930	COG1162	GTPase activity
EGY05_RS06935	COG0105	UTP biosynthetic process
EGY05_RS06965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGY05_RS06970	COG1363	Peptidase, m42
EGY05_RS06985	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EGY05_RS06985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGY05_RS07000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGY05_RS07050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGY05_RS07055	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EGY05_RS07060	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGY05_RS07090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGY05_RS07095	COG0450	alkyl hydroperoxide reductase
EGY05_RS07100	COG0436	Aminotransferase
EGY05_RS07105	COG0357	Ribosomal RNA small subunit methyltransferase G
EGY05_RS07135	COG1960	acyl-CoA dehydrogenase activity
EGY05_RS07150	COG4771	TonB-dependent receptor
EGY05_RS07165	COG1472	Belongs to the glycosyl hydrolase 3 family
EGY05_RS07180	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EGY05_RS07190	COG0519	Catalyzes the synthesis of GMP from XMP
EGY05_RS07200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGY05_RS07210	COG0813	purine-nucleoside phosphorylase activity
EGY05_RS07220	COG1858	cytochrome C peroxidase
EGY05_RS07255	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EGY05_RS07280	COG2076	Multidrug Resistance protein
EGY05_RS07290	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EGY05_RS07300	COG1506	peptidase
EGY05_RS07315	COG1247	-acetyltransferase
EGY05_RS07325	COG0534	Mate efflux family protein
EGY05_RS07335	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGY05_RS07350	COG2217	Heavy metal translocating P-type atpase
EGY05_RS07360	COG1607	acyl-coa hydrolase
EGY05_RS07370	COG3655	Transcriptional regulator
EGY05_RS07375	COG0724	RNA recognition motif
EGY05_RS07410	COG1136	(ABC) transporter
EGY05_RS07420	COG2003	Belongs to the UPF0758 family
EGY05_RS07445	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EGY05_RS07450	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EGY05_RS07475	COG0183	Belongs to the thiolase family
EGY05_RS07490	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EGY05_RS07495	COG0300	oxidoreductase activity
EGY05_RS07515	COG2207	Transcriptional regulator
EGY05_RS07565	COG2207	Transcriptional regulator
EGY05_RS07640	COG0596	Alpha beta hydrolase
EGY05_RS07650	COG4106	trans-aconitate 2-methyltransferase activity
EGY05_RS07655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGY05_RS07660	COG4206	TonB-dependent receptor
EGY05_RS07675	COG3422	double-strand break repair
EGY05_RS07690	COG1960	acyl-CoA dehydrogenase activity
EGY05_RS07705	COG0183	Belongs to the thiolase family
EGY05_RS07715	COG1024	Enoyl-CoA hydratase
EGY05_RS07715	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGY05_RS07725	COG1120	ATPase activity
EGY05_RS07735	COG3118	belongs to the thioredoxin family
EGY05_RS07745	COG2949	membrane
EGY05_RS07755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGY05_RS07785	COG0528	UMP kinase activity
EGY05_RS07800	COG0596	Alpha beta hydrolase
EGY05_RS07805	COG0233	cytoplasmic translational termination
EGY05_RS07825	COG1674	ftsk spoiiie
EGY05_RS07830	COG1335	isochorismatase
EGY05_RS07840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGY05_RS07840	COG1333	cytochrome c biogenesis protein
EGY05_RS07855	COG1012	belongs to the aldehyde dehydrogenase family
EGY05_RS07945	COG1396	sequence-specific DNA binding
EGY05_RS08205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGY05_RS08250	COG1609	Transcriptional regulator
EGY05_RS08265	COG0572	uridine kinase
EGY05_RS08295	COG0791	NLP P60 protein
EGY05_RS08310	COG2814	Major facilitator Superfamily
EGY05_RS08335	COG0463	Glycosyl transferase, family 2
EGY05_RS08350	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EGY05_RS08355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGY05_RS08360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGY05_RS08365	COG0131	Imidazoleglycerol-phosphate dehydratase
EGY05_RS08375	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EGY05_RS08380	COG0107	imidazoleglycerol-phosphate synthase activity
EGY05_RS08385	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGY05_RS08385	COG0140	phosphoribosyl-ATP diphosphatase activity
EGY05_RS08440	COG2234	aminopeptidase activity
EGY05_RS08445	COG2234	aminopeptidase activity
EGY05_RS08450	COG2234	aminopeptidase activity
EGY05_RS08455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EGY05_RS08460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EGY05_RS08505	COG2197	response regulator
EGY05_RS08525	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EGY05_RS08530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EGY05_RS08550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGY05_RS08555	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EGY05_RS08560	COG0066	3-isopropylmalate dehydratase activity
EGY05_RS08605	COG3279	Response regulator of the LytR AlgR family
EGY05_RS08615	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGY05_RS08645	COG1960	acyl-CoA dehydrogenase activity
EGY05_RS08675	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EGY05_RS08705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EGY05_RS08710	COG1187	pseudouridine synthase activity
EGY05_RS08715	COG1335	isochorismatase
EGY05_RS08720	COG0513	Belongs to the DEAD box helicase family
EGY05_RS08725	COG2318	DinB family
EGY05_RS08735	COG3118	belongs to the thioredoxin family
EGY05_RS08745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGY05_RS08750	COG0697	spore germination
EGY05_RS08770	COG3685	Protein conserved in bacteria
EGY05_RS08785	COG0753	catalase activity
EGY05_RS08790	COG1063	alcohol dehydrogenase
EGY05_RS08795	COG1058	Belongs to the CinA family
EGY05_RS08795	COG1546	Belongs to the CinA family
EGY05_RS08800	COG0300	oxidoreductase activity
EGY05_RS08805	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS08810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGY05_RS08810	COG0723	plastoquinol--plastocyanin reductase activity
EGY05_RS08840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGY05_RS08850	COG3871	stress protein (general stress protein 26)
EGY05_RS08860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGY05_RS08870	COG2814	Major facilitator Superfamily
EGY05_RS08885	COG2814	Major facilitator Superfamily
EGY05_RS08895	COG0588	phosphoglycerate mutase activity
EGY05_RS08905	COG1793	dna ligase
EGY05_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS08950	COG1201	RNA secondary structure unwinding
EGY05_RS08955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGY05_RS08975	COG2814	Major facilitator Superfamily
EGY05_RS08980	COG3501	Rhs element vgr protein
EGY05_RS08990	COG0666	response to abiotic stimulus
EGY05_RS09010	COG1733	regulation of RNA biosynthetic process
EGY05_RS09025	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EGY05_RS09035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGY05_RS09075	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EGY05_RS09085	COG0076	glutamate decarboxylase activity
EGY05_RS09095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGY05_RS09110	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EGY05_RS09115	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EGY05_RS09120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EGY05_RS09125	COG1733	regulation of RNA biosynthetic process
EGY05_RS09130	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EGY05_RS09135	COG2807	transmembrane transport
EGY05_RS09140	COG2207	Transcriptional regulator
EGY05_RS09200	COG0667	Aldo Keto reductase
EGY05_RS09210	COG0300	oxidoreductase activity
EGY05_RS09215	COG1252	NADH dehydrogenase
EGY05_RS09230	COG5002	protein histidine kinase activity
EGY05_RS09255	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS09275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGY05_RS09285	COG2972	Histidine kinase
EGY05_RS09290	COG3279	Response regulator of the LytR AlgR family
EGY05_RS09295	COG4771	TonB-dependent receptor
EGY05_RS09310	COG2094	Belongs to the DNA glycosylase MPG family
EGY05_RS09315	COG1506	peptidase
EGY05_RS09315	COG0823	Involved in the tonB-independent uptake of proteins
EGY05_RS09315	COG4946	Tricorn protease homolog
EGY05_RS09320	COG0006	proline dipeptidase activity
EGY05_RS09330	COG1959	2 iron, 2 sulfur cluster binding
EGY05_RS09335	COG0175	sulfate reduction
EGY05_RS09340	COG0175	sulfate reduction
EGY05_RS09350	COG1045	serine acetyltransferase
EGY05_RS09365	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGY05_RS09380	COG1648	precorrin-2 dehydrogenase activity
EGY05_RS09380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EGY05_RS09425	COG0523	cobalamin synthesis protein
EGY05_RS09430	COG3279	Response regulator of the LytR AlgR family
EGY05_RS09435	COG2972	Histidine kinase
EGY05_RS09450	COG1595	DNA-templated transcription, initiation
EGY05_RS09455	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGY05_RS09460	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EGY05_RS09480	COG3620	sequence-specific DNA binding
EGY05_RS09535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EGY05_RS09540	COG0640	Transcriptional regulator
EGY05_RS09550	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EGY05_RS09585	COG1104	cysteine desulfurase activity
EGY05_RS09610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGY05_RS09650	COG2132	Multicopper oxidase
EGY05_RS09670	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EGY05_RS09695	COG0156	8-amino-7-oxononanoate synthase activity
EGY05_RS09720	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EGY05_RS09725	COG0196	riboflavin kinase activity
EGY05_RS09745	COG0702	epimerase
EGY05_RS09750	COG0386	Belongs to the glutathione peroxidase family
EGY05_RS09760	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EGY05_RS09780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGY05_RS09800	COG0463	Glycosyl transferase, family 2
EGY05_RS09815	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EGY05_RS09825	COG1575	Belongs to the MenA family. Type 1 subfamily
EGY05_RS09865	COG2323	membrane
EGY05_RS09915	COG0531	amino acid
EGY05_RS09960	COG2270	Major facilitator Superfamily
EGY05_RS09965	COG0183	Belongs to the thiolase family
EGY05_RS09990	COG1595	DNA-templated transcription, initiation
EGY05_RS09995	COG2211	Major facilitator Superfamily
EGY05_RS10005	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EGY05_RS10015	COG0300	oxidoreductase activity
EGY05_RS10050	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGY05_RS10050	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGY05_RS10060	COG0572	uridine kinase
EGY05_RS10075	COG1253	flavin adenine dinucleotide binding
EGY05_RS10080	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EGY05_RS10085	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EGY05_RS10090	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGY05_RS10095	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EGY05_RS10100	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGY05_RS10105	COG0356	it plays a direct role in the translocation of protons across the membrane
EGY05_RS10110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGY05_RS10145	COG1702	phosphate starvation-inducible protein PhoH
EGY05_RS10155	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGY05_RS10170	COG1733	regulation of RNA biosynthetic process
EGY05_RS10195	COG0360	Binds together with S18 to 16S ribosomal RNA
EGY05_RS10200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGY05_RS10205	COG0359	binds to the 23S rRNA
EGY05_RS10230	COG1012	belongs to the aldehyde dehydrogenase family
EGY05_RS10260	COG2967	ApaG domain
EGY05_RS10265	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGY05_RS10280	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EGY05_RS10290	COG0297	glycogen (starch) synthase activity
EGY05_RS10295	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EGY05_RS10305	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EGY05_RS10325	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EGY05_RS10350	COG4242	Belongs to the peptidase S51 family
EGY05_RS10355	COG1446	asparaginase
EGY05_RS10365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EGY05_RS10410	COG0124	histidyl-tRNA synthetase
EGY05_RS10420	COG0629	single-stranded DNA binding
EGY05_RS10440	COG1090	epimerase
EGY05_RS10445	COG0494	nUDIX hydrolase
EGY05_RS10480	COG0484	heat shock protein binding
EGY05_RS10500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY05_RS10505	COG1538	Outer membrane efflux protein
EGY05_RS10515	COG2996	Protein conserved in bacteria
EGY05_RS10530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGY05_RS10560	COG0438	transferase activity, transferring glycosyl groups
EGY05_RS10565	COG0514	ATP-dependent DNA helicase (RecQ)
EGY05_RS10570	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EGY05_RS10570	COG0517	IMP dehydrogenase activity
EGY05_RS10585	COG0805	protein transport
EGY05_RS10600	COG3852	Histidine kinase
EGY05_RS10605	COG2027	D-alanyl-D-alanine carboxypeptidase
EGY05_RS10615	COG3340	Belongs to the peptidase S51 family
EGY05_RS10630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGY05_RS10675	COG0456	acetyltransferase
EGY05_RS10715	COG0009	L-threonylcarbamoyladenylate synthase
EGY05_RS10725	COG3022	response to hydroperoxide
EGY05_RS10735	COG2890	protein-(glutamine-N5) methyltransferase activity
EGY05_RS10750	COG0300	oxidoreductase activity
EGY05_RS10780	COG2972	Histidine kinase
EGY05_RS10785	COG3279	Response regulator of the LytR AlgR family
EGY05_RS10795	COG0436	Aminotransferase
EGY05_RS10810	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS10835	COG0012	GTP binding
EGY05_RS10840	COG1528	Iron-storage protein
EGY05_RS10845	COG1649	PFAM Uncharacterised BCR, COG1649
EGY05_RS10850	COG1217	gtp-binding protein TYPA
EGY05_RS10855	COG0693	protein deglycase activity
EGY05_RS10940	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EGY05_RS10955	COG2183	response to ionizing radiation
EGY05_RS11020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGY05_RS11035	COG2814	Major facilitator Superfamily
EGY05_RS11045	COG2706	6-phosphogluconolactonase activity
EGY05_RS11100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGY05_RS11100	COG0551	DNA topoisomerase type I activity
EGY05_RS11110	COG0798	PFAM Bile acid sodium symporter
EGY05_RS11135	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EGY05_RS11145	COG2132	Multicopper oxidase
EGY05_RS11170	COG2217	Heavy metal translocating P-type atpase
EGY05_RS11200	COG2217	Heavy metal translocating P-type atpase
EGY05_RS11225	COG2801	Transposase and inactivated derivatives
EGY05_RS11230	COG2963	transposase activity
EGY05_RS11475	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EGY05_RS11480	COG0415	Belongs to the DNA photolyase family
EGY05_RS11490	COG2204	response regulator
EGY05_RS11500	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EGY05_RS11505	COG3437	response regulator, receiver
EGY05_RS11510	COG2205	protein histidine kinase activity
EGY05_RS11510	COG0784	Response regulator, receiver
EGY05_RS11530	COG0702	epimerase
EGY05_RS11535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGY05_RS11535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGY05_RS11590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGY05_RS11595	COG0738	Major facilitator superfamily
EGY05_RS11600	COG1082	Xylose isomerase domain protein TIM barrel
EGY05_RS11615	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EGY05_RS11645	COG0318	PFAM AMP-dependent synthetase and ligase
EGY05_RS11685	COG0531	amino acid
EGY05_RS11720	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EGY05_RS11740	COG3275	phosphorelay sensor kinase activity
EGY05_RS11760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGY05_RS11765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGY05_RS11780	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGY05_RS11780	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGY05_RS11835	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS11915	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EGY05_RS11935	COG4771	TonB-dependent receptor
EGY05_RS11945	COG0667	Aldo Keto reductase
EGY05_RS11950	COG0662	Cupin 2, conserved barrel domain protein
EGY05_RS11950	COG2207	Transcriptional regulator
EGY05_RS11980	COG1595	DNA-templated transcription, initiation
EGY05_RS11995	COG1012	belongs to the aldehyde dehydrogenase family
EGY05_RS12015	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EGY05_RS12025	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EGY05_RS12035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGY05_RS12045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EGY05_RS12070	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGY05_RS12090	COG3059	membrane
EGY05_RS12100	COG0739	heme binding
EGY05_RS12105	COG0592	DNA-directed DNA polymerase activity
EGY05_RS12215	COG0702	epimerase
EGY05_RS12220	COG1629	transport
EGY05_RS12245	COG1393	Belongs to the ArsC family
EGY05_RS12250	COG1428	Deoxynucleoside kinase
EGY05_RS12280	COG0025	NhaP-type Na H and K H
EGY05_RS12285	COG3781	membrane
EGY05_RS12300	COG2197	response regulator
EGY05_RS12305	COG4585	Histidine kinase
EGY05_RS12370	COG4574	serine-type endopeptidase inhibitor activity
EGY05_RS12390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGY05_RS12410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGY05_RS12450	COG2003	Belongs to the UPF0758 family
EGY05_RS12580	COG4771	TonB-dependent receptor
EGY05_RS12610	COG0653	protein targeting
EGY05_RS12655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGY05_RS12665	COG1538	Outer membrane efflux protein
EGY05_RS12685	COG1538	Outer membrane efflux protein
EGY05_RS12695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY05_RS12715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EGY05_RS12720	COG3264	Mechanosensitive ion channel
EGY05_RS12720	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EGY05_RS12800	COG2963	transposase activity
EGY05_RS12805	COG2801	Transposase and inactivated derivatives
EGY05_RS12890	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGY05_RS12895	COG1309	transcriptional regulator
EGY05_RS12900	COG0300	oxidoreductase activity
EGY05_RS12920	COG0561	phosphatase activity
EGY05_RS12925	COG1085	galactose-1-phosphate uridylyltransferase
EGY05_RS12930	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EGY05_RS12935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGY05_RS12950	COG3661	Belongs to the glycosyl hydrolase 67 family
EGY05_RS12965	COG2211	Major facilitator Superfamily
EGY05_RS13000	COG2160	L-arabinose isomerase activity
EGY05_RS13010	COG1069	ribulokinase activity
EGY05_RS13035	COG4948	Mandelate Racemase Muconate Lactonizing
EGY05_RS13040	COG3507	Belongs to the glycosyl hydrolase 43 family
EGY05_RS13045	COG3693	PFAM glycoside hydrolase, family 10
EGY05_RS13045	COG3507	Belongs to the glycosyl hydrolase 43 family
EGY05_RS13045	COG2382	esterase
EGY05_RS13050	COG3507	Belongs to the glycosyl hydrolase 43 family
EGY05_RS13060	COG2271	Major facilitator Superfamily
EGY05_RS13075	COG1904	glucuronate isomerase
EGY05_RS13080	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS13085	COG1312	Catalyzes the dehydration of D-mannonate
EGY05_RS13095	COG1629	transport
EGY05_RS13100	COG2115	Belongs to the xylose isomerase family
EGY05_RS13135	COG1131	(ABC) transporter
EGY05_RS13390	COG0740	serine-type endopeptidase activity
EGY05_RS13450	COG1876	peptidase activity
EGY05_RS13740	COG1222	aaa ATPase
EGY05_RS13760	COG1917	Cupin 2, conserved barrel domain protein
EGY05_RS13760	COG4977	sequence-specific DNA binding
EGY05_RS13770	COG1012	belongs to the aldehyde dehydrogenase family
EGY05_RS13800	COG4771	TonB-dependent receptor
EGY05_RS13840	COG2972	Histidine kinase
EGY05_RS13840	COG0745	RESPONSE REGULATOR receiver
EGY05_RS13845	COG3279	Response regulator of the LytR AlgR family
EGY05_RS13855	COG1131	(ABC) transporter
EGY05_RS13875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGY05_RS13920	COG2304	oxidoreductase activity
EGY05_RS13925	COG4206	TonB-dependent receptor
EGY05_RS13925	COG1629	transport
EGY05_RS13940	COG1902	pentaerythritol trinitrate reductase activity
EGY05_RS13945	COG1733	regulation of RNA biosynthetic process
EGY05_RS13955	COG0022	dehydrogenase e1 component
EGY05_RS13970	COG0142	geranyltranstransferase activity
EGY05_RS13985	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EGY05_RS13990	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EGY05_RS14010	COG0673	inositol 2-dehydrogenase activity
EGY05_RS14030	COG1506	peptidase
EGY05_RS14030	COG0823	Involved in the tonB-independent uptake of proteins
EGY05_RS14035	COG1950	PFAM Membrane protein of
EGY05_RS14100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGY05_RS14105	COG2011	ABC-type metal ion transport system permease component
EGY05_RS14110	COG1464	Belongs to the NlpA lipoprotein family
EGY05_RS14115	COG1472	Belongs to the glycosyl hydrolase 3 family
EGY05_RS14140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY05_RS14145	COG2207	Transcriptional regulator
EGY05_RS14175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EGY05_RS14205	COG3590	peptidase
EGY05_RS14250	COG3321	synthase
EGY05_RS14250	COG0604	alcohol dehydrogenase
EGY05_RS14255	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS14255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGY05_RS14255	COG4221	oxidoreductase activity
EGY05_RS14255	COG3321	synthase
EGY05_RS14260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGY05_RS14295	COG0270	DNA (cytosine-5-)-methyltransferase activity
EGY05_RS14380	COG1280	lysine exporter protein (LysE YggA)
EGY05_RS14400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGY05_RS14400	COG2207	Transcriptional regulator
EGY05_RS14410	COG0006	proline dipeptidase activity
EGY05_RS14440	COG4413	Urea transporter
EGY05_RS14450	COG0829	nickel cation binding
EGY05_RS14455	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EGY05_RS14460	COG0830	nickel cation binding
EGY05_RS14465	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EGY05_RS14475	COG0804	urea catabolic process
EGY05_RS14480	COG0832	Belongs to the urease beta subunit family
EGY05_RS14485	COG0831	urea catabolic process
EGY05_RS14495	COG1012	belongs to the aldehyde dehydrogenase family
EGY05_RS14520	COG3118	belongs to the thioredoxin family
EGY05_RS14525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGY05_RS14530	COG0598	Magnesium transport protein CorA
EGY05_RS14540	COG0277	FAD linked oxidase domain protein
EGY05_RS14565	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGY05_RS14570	COG1733	regulation of RNA biosynthetic process
EGY05_RS14575	COG0519	Catalyzes the synthesis of GMP from XMP
EGY05_RS14600	COG2814	Major facilitator Superfamily
EGY05_RS14615	COG1309	transcriptional regulator
EGY05_RS14670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGY05_RS14705	COG0071	Belongs to the small heat shock protein (HSP20) family
EGY05_RS14715	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EGY05_RS14725	COG4682	membrane
EGY05_RS14730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EGY05_RS14735	COG0697	spore germination
EGY05_RS14745	COG0589	response to stress
EGY05_RS14745	COG0475	glutathione-regulated potassium exporter activity
EGY05_RS14765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGY05_RS14775	COG0730	response to heat
EGY05_RS14785	COG0346	lactoylglutathione lyase activity
EGY05_RS14810	COG1022	Amp-dependent synthetase and ligase
EGY05_RS14815	COG1086	Polysaccharide biosynthesis protein
EGY05_RS14840	COG2267	carboxylic ester hydrolase activity
EGY05_RS14845	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EGY05_RS14850	COG0668	transmembrane transport
EGY05_RS14880	COG1193	negative regulation of DNA recombination
EGY05_RS14895	COG1607	acyl-coa hydrolase
EGY05_RS14950	COG1169	isochorismate synthase
EGY05_RS14960	COG2095	MarC family integral membrane protein
EGY05_RS14980	COG2304	oxidoreductase activity
EGY05_RS15000	COG0714	Associated with various cellular activities
EGY05_RS15020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGY05_RS15050	COG0492	ferredoxin-NADP+ reductase activity
EGY05_RS15080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGY05_RS15100	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EGY05_RS15105	COG0527	aspartate kinase activity
EGY05_RS15180	COG3279	Response regulator of the LytR AlgR family
EGY05_RS15185	COG0702	epimerase
EGY05_RS15190	COG4206	TonB-dependent receptor
EGY05_RS15190	COG1629	transport
EGY05_RS15200	COG3275	phosphorelay sensor kinase activity
EGY05_RS15210	COG0596	Alpha beta hydrolase
EGY05_RS15220	COG3118	belongs to the thioredoxin family
EGY05_RS15235	COG3876	Protein conserved in bacteria
EGY05_RS15265	COG1301	dicarboxylic acid transport
EGY05_RS15280	COG1012	belongs to the aldehyde dehydrogenase family
EGY05_RS15285	COG2207	Transcriptional regulator
EGY05_RS15285	COG1917	Cupin 2, conserved barrel domain protein
EGY05_RS15290	COG0702	epimerase
EGY05_RS15295	COG4771	TonB-dependent receptor
EGY05_RS15300	COG3425	synthase
EGY05_RS15345	COG5002	protein histidine kinase activity
EGY05_RS15350	COG0745	RESPONSE REGULATOR receiver
EGY05_RS15365	COG0402	S-adenosylhomocysteine deaminase activity
EGY05_RS15375	COG0666	response to abiotic stimulus
EGY05_RS15380	COG0402	S-adenosylhomocysteine deaminase activity
EGY05_RS15390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EGY05_RS15400	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EGY05_RS15435	COG1704	LemA family
EGY05_RS15490	COG3501	Rhs element vgr protein
EGY05_RS15510	COG0295	cytidine deaminase activity
EGY05_RS15515	COG2732	(Barnase) inhibitor
EGY05_RS15530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGY05_RS15540	COG0519	Catalyzes the synthesis of GMP from XMP
EGY05_RS15560	COG0626	cystathionine gamma-synthase activity
EGY05_RS15565	COG0456	acetyltransferase
EGY05_RS15580	COG0009	L-threonylcarbamoyladenylate synthase
EGY05_RS15590	COG0617	tRNA 3'-terminal CCA addition
EGY05_RS15600	COG4206	TonB-dependent receptor
EGY05_RS15620	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
EGY05_RS15675	COG0596	Alpha beta hydrolase
EGY05_RS15690	COG4251	negative regulation of phosphorylation
EGY05_RS15705	COG0471	metal ion transport
EGY05_RS15715	COG1053	succinate dehydrogenase
EGY05_RS15720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGY05_RS15775	COG1858	cytochrome C peroxidase
EGY05_RS15800	COG0443	Heat shock 70 kDa protein
EGY05_RS15825	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGY05_RS15830	COG0248	Ppx GppA phosphatase
EGY05_RS15875	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EGY05_RS15880	COG0489	protein tyrosine kinase activity
EGY05_RS15905	COG3537	Alpha-1,2-mannosidase
EGY05_RS15915	COG1301	dicarboxylic acid transport
EGY05_RS15950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGY05_RS15955	COG0010	Belongs to the arginase family
EGY05_RS15960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGY05_RS15970	COG2365	Tyrosine phosphatase family
EGY05_RS16000	COG2378	regulation of single-species biofilm formation
EGY05_RS16005	COG1132	(ABC) transporter
EGY05_RS16015	COG1137	ATPase activity
EGY05_RS16035	COG0113	porphobilinogen synthase activity
EGY05_RS16045	COG4152	abc transporter atp-binding protein
EGY05_RS16050	COG1668	transmembrane transport
EGY05_RS16060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGY05_RS16070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EGY05_RS16080	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGY05_RS16085	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EGY05_RS16085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EGY05_RS16090	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGY05_RS16095	COG1078	dGTPase activity
EGY05_RS16115	COG0708	Exodeoxyribonuclease III
EGY05_RS16120	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGY05_RS16135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGY05_RS16145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EGY05_RS16150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGY05_RS16165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EGY05_RS16205	COG0482	sulfurtransferase activity
EGY05_RS16235	COG0482	sulfurtransferase activity
EGY05_RS16250	COG0110	maltose O-acetyltransferase activity
EGY05_RS16280	COG0579	oxidoreductase
EGY05_RS16285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EGY05_RS16290	COG0489	protein tyrosine kinase activity
EGY05_RS16290	COG3206	protein involved in exopolysaccharide biosynthesis
EGY05_RS16305	COG2137	regulation of response to DNA damage stimulus
EGY05_RS16310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EGY05_RS16330	COG1136	(ABC) transporter
EGY05_RS16330	COG0577	efflux transmembrane transporter activity
EGY05_RS16335	COG0577	efflux transmembrane transporter activity
EGY05_RS16335	COG1136	(ABC) transporter
EGY05_RS16340	COG1136	(ABC) transporter
EGY05_RS16385	COG1418	mRNA catabolic process
EGY05_RS16395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGY05_RS16405	COG0525	valine-tRNA ligase activity
EGY05_RS16415	COG2326	polyphosphate kinase activity
EGY05_RS16435	COG0318	PFAM AMP-dependent synthetase and ligase
EGY05_RS16445	COG0017	Asparaginyl-tRNA synthetase
EGY05_RS16480	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS16495	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EGY05_RS16500	COG0228	four-way junction DNA binding
EGY05_RS16530	COG0339	signal peptide processing
EGY05_RS16575	COG2226	methyltransferase
EGY05_RS16580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY05_RS16585	COG0477	Major facilitator Superfamily
EGY05_RS16645	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGY05_RS16650	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGY05_RS16665	COG1247	-acetyltransferase
EGY05_RS16680	COG4245	von Willebrand factor, type A
EGY05_RS16695	COG2310	stress, protein
EGY05_RS16705	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EGY05_RS16715	COG0259	pyridoxamine-phosphate oxidase activity
EGY05_RS16720	COG1678	Uncharacterized ACR, COG1678
EGY05_RS16740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGY05_RS16755	COG3158	transport of potassium into the cell
EGY05_RS16760	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGY05_RS16760	COG0022	dehydrogenase e1 component
EGY05_RS16785	COG1183	phosphatidylcholine synthase activity
EGY05_RS16810	COG0589	response to stress
EGY05_RS16845	COG0612	Peptidase, M16
EGY05_RS16855	COG0544	peptidyl-prolyl cis-trans isomerase activity
EGY05_RS16875	COG0488	(ABC) transporter
EGY05_RS16895	COG4585	Histidine kinase
EGY05_RS16930	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGY05_RS16935	COG0720	synthase
EGY05_RS16970	COG2224	Isocitrate lyase
EGY05_RS16975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGY05_RS16985	COG1040	competence protein
EGY05_RS16995	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EGY05_RS17000	COG1160	GTP binding
EGY05_RS17010	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EGY05_RS17035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGY05_RS17050	COG0745	RESPONSE REGULATOR receiver
EGY05_RS17060	COG5006	permease, DMT superfamily
EGY05_RS17065	COG1285	pathogenesis
EGY05_RS17095	COG0436	Aminotransferase
EGY05_RS17105	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EGY05_RS17120	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EGY05_RS17135	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EGY05_RS17140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGY05_RS17155	COG0552	protein localization to endoplasmic reticulum
EGY05_RS17160	COG2261	transglycosylase associated protein
EGY05_RS17165	COG0616	signal peptide processing
EGY05_RS17195	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EGY05_RS17200	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGY05_RS17200	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGY05_RS17205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGY05_RS17220	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGY05_RS17230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGY05_RS17245	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EGY05_RS17260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGY05_RS17280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGY05_RS17280	COG2207	Transcriptional regulator
EGY05_RS17295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY05_RS17315	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EGY05_RS17320	COG1561	YicC-like family, N-terminal region
EGY05_RS17325	COG0194	GDP metabolic process
EGY05_RS17330	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EGY05_RS17365	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EGY05_RS17370	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EGY05_RS17410	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EGY05_RS17430	COG0284	orotidine-5'-phosphate decarboxylase activity
EGY05_RS17430	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EGY05_RS17465	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGY05_RS17470	COG1522	sequence-specific DNA binding
EGY05_RS17480	COG0336	Belongs to the RNA methyltransferase TrmD family
EGY05_RS17485	COG1252	NADH dehydrogenase
EGY05_RS17505	COG0488	(ABC) transporter
EGY05_RS17510	COG0673	inositol 2-dehydrogenase activity
EGY05_RS17515	COG4206	TonB-dependent receptor
EGY05_RS17530	COG0450	alkyl hydroperoxide reductase
EGY05_RS17535	COG0668	transmembrane transport
EGY05_RS17545	COG0045	succinate-CoA ligase (ADP-forming) activity
EGY05_RS17550	COG1132	(ABC) transporter
EGY05_RS17565	COG0038	chloride channel
EGY05_RS17570	COG2363	Small membrane protein
EGY05_RS17585	COG0632	four-way junction helicase activity
EGY05_RS17595	COG4335	DNA alkylation repair
EGY05_RS17605	COG1733	regulation of RNA biosynthetic process
EGY05_RS17615	COG0205	6-phosphofructokinase activity
EGY05_RS17640	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EGY05_RS17650	COG1506	peptidase
EGY05_RS17650	COG0823	Involved in the tonB-independent uptake of proteins
EGY05_RS17655	COG0326	Molecular chaperone. Has ATPase activity
EGY05_RS17670	COG1899	peptidyl-lysine modification to peptidyl-hypusine
EGY05_RS17790	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EGY05_RS17860	COG1113	amino acid transport
EGY05_RS17880	COG2205	protein histidine kinase activity
EGY05_RS17895	COG2010	Cytochrome c
EGY05_RS17915	COG0018	arginyl-trna synthetase
EGY05_RS17930	COG4771	TonB-dependent receptor
EGY05_RS17945	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGY05_RS17950	COG0706	membrane insertase activity
EGY05_RS17955	COG0504	CTP synthase activity
EGY05_RS17960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGY05_RS17965	COG4589	Belongs to the CDS family
EGY05_RS17975	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS17980	COG2453	phosphatase
EGY05_RS17980	COG0671	phosphoesterase, PA-phosphatase related
EGY05_RS17985	COG2267	carboxylic ester hydrolase activity
EGY05_RS17990	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EGY05_RS18040	COG3279	Response regulator of the LytR AlgR family
EGY05_RS18055	COG2851	Citrate transporter
EGY05_RS18060	COG1301	dicarboxylic acid transport
EGY05_RS18065	COG0861	Integral membrane protein TerC family
EGY05_RS18070	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EGY05_RS18160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY05_RS18195	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EGY05_RS18215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY05_RS18255	COG2267	carboxylic ester hydrolase activity
EGY05_RS18295	COG0745	RESPONSE REGULATOR receiver
EGY05_RS18300	COG5002	protein histidine kinase activity
EGY05_RS18310	COG0477	Major facilitator Superfamily
EGY05_RS18330	COG1595	DNA-templated transcription, initiation
EGY05_RS18350	COG1132	(ABC) transporter
EGY05_RS18355	COG0101	tRNA pseudouridine synthase activity
EGY05_RS18360	COG1663	tetraacyldisaccharide 4'-kinase activity
EGY05_RS18370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGY05_RS18375	COG0456	acetyltransferase
EGY05_RS18380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGY05_RS18385	COG0366	Alpha amylase catalytic
EGY05_RS18390	COG2272	Belongs to the type-B carboxylesterase lipase family
EGY05_RS18400	COG1064	alcohol dehydrogenase
EGY05_RS18405	COG1733	regulation of RNA biosynthetic process
EGY05_RS18435	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EGY05_RS18470	COG4771	TonB-dependent receptor
EGY05_RS18495	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EGY05_RS18500	COG0085	RNA polymerase activity
EGY05_RS18535	COG0222	ribosome binding
EGY05_RS18540	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EGY05_RS18545	COG0081	regulation of translation
EGY05_RS18550	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EGY05_RS18595	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EGY05_RS18625	COG0745	RESPONSE REGULATOR receiver
EGY05_RS18665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGY05_RS18670	COG4974	Belongs to the 'phage' integrase family
EGY05_RS18675	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EGY05_RS18700	COG2197	response regulator
EGY05_RS18750	COG0431	NADPH-dependent FMN reductase
EGY05_RS18760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGY05_RS18765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGY05_RS18770	COG0571	ribonuclease III activity
EGY05_RS18780	COG0469	pyruvate kinase activity
EGY05_RS18785	COG1012	belongs to the aldehyde dehydrogenase family
EGY05_RS18790	COG0010	Belongs to the arginase family
EGY05_RS18800	COG1228	amidohydrolase
EGY05_RS18805	COG2255	four-way junction helicase activity
EGY05_RS18810	COG2808	Putative FMN-binding domain
EGY05_RS18815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGY05_RS18820	COG0237	dephospho-CoA kinase activity
EGY05_RS18850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGY05_RS18860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGY05_RS18865	COG1053	succinate dehydrogenase
EGY05_RS18875	COG2333	competence protein COMEC
EGY05_RS18875	COG0658	competence protein
EGY05_RS18885	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGY05_RS18910	COG0534	Mate efflux family protein
EGY05_RS18920	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EGY05_RS18930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EGY05_RS18940	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EGY05_RS18960	COG0668	transmembrane transport
EGY05_RS18965	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS18970	COG1862	Preprotein translocase
EGY05_RS18980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGY05_RS18985	COG1132	(ABC) transporter
EGY05_RS19005	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGY05_RS19045	COG0495	leucyl-tRNA aminoacylation
EGY05_RS19060	COG1215	transferase activity, transferring glycosyl groups
EGY05_RS19070	COG1519	Transferase
EGY05_RS19105	COG0037	tRNA processing
EGY05_RS19155	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EGY05_RS19160	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EGY05_RS19165	COG2884	Cell division ATP-binding protein ftsE
EGY05_RS19170	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EGY05_RS19175	COG5000	phosphorelay sensor kinase activity
EGY05_RS19185	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EGY05_RS19195	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EGY05_RS19200	COG0511	ligase activity, forming carbon-carbon bonds
EGY05_RS19205	COG0439	Biotin carboxylase
EGY05_RS19260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGY05_RS19265	COG0825	malonyl-CoA metabolic process
EGY05_RS19275	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EGY05_RS19310	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EGY05_RS19325	COG0052	Belongs to the universal ribosomal protein uS2 family
EGY05_RS19330	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EGY05_RS19335	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EGY05_RS19350	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGY05_RS19350	COG1703	isobutyryl-CoA mutase activity
EGY05_RS19350	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGY05_RS19395	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EGY05_RS19435	COG0516	GMP reductase activity
EGY05_RS19435	COG0517	IMP dehydrogenase activity
EGY05_RS19460	COG1595	DNA-templated transcription, initiation
EGY05_RS19470	COG0254	rRNA binding
EGY05_RS19510	COG0702	epimerase
EGY05_RS19515	COG4771	TonB-dependent receptor
EGY05_RS19520	COG0300	oxidoreductase activity
EGY05_RS19530	COG4771	TonB-dependent receptor
EGY05_RS19540	COG3511	phospholipase C
EGY05_RS19575	COG4771	TonB-dependent receptor
EGY05_RS19655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGY05_RS19660	COG1442	glycosyl transferase family 8
EGY05_RS19660	COG1216	Glycosyl transferase, family 2
EGY05_RS19700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGY05_RS19720	COG0612	Peptidase, M16
EGY05_RS19735	COG1131	(ABC) transporter
EGY05_RS19750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGY05_RS19765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGY05_RS19790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EGY05_RS19810	COG1073	alpha beta
EGY05_RS19825	COG0644	oxidoreductase
EGY05_RS19835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGY05_RS19840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGY05_RS19845	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS19850	COG2986	histidine ammonia-lyase
EGY05_RS19865	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EGY05_RS19870	COG0739	heme binding
EGY05_RS19875	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EGY05_RS19880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EGY05_RS19895	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EGY05_RS19900	COG2949	membrane
EGY05_RS19905	COG0180	Tryptophanyl-tRNA synthetase
EGY05_RS19910	COG5002	protein histidine kinase activity
EGY05_RS19915	COG0745	RESPONSE REGULATOR receiver
EGY05_RS19930	COG0546	phosphoglycolate phosphatase activity
EGY05_RS19945	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EGY05_RS19960	COG1024	Enoyl-CoA hydratase
EGY05_RS19970	COG4974	Belongs to the 'phage' integrase family
EGY05_RS19990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGY05_RS19995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGY05_RS20000	COG1607	acyl-coa hydrolase
EGY05_RS20025	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EGY05_RS20050	COG3279	Response regulator of the LytR AlgR family
EGY05_RS20055	COG3275	phosphorelay sensor kinase activity
EGY05_RS20085	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EGY05_RS20090	COG2022	thiamine diphosphate biosynthetic process
EGY05_RS20095	COG0352	thiamine-phosphate diphosphorylase activity
EGY05_RS20100	COG0352	thiamine-phosphate diphosphorylase activity
EGY05_RS20120	COG0564	pseudouridine synthase activity
EGY05_RS20130	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EGY05_RS20135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGY05_RS20140	COG2217	Heavy metal translocating P-type atpase
EGY05_RS20165	COG0348	domain, Protein
EGY05_RS20185	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EGY05_RS20220	COG2181	nitrate reductase activity
EGY05_RS20220	COG0247	lactate metabolic process
EGY05_RS20225	COG2181	nitrate reductase activity
EGY05_RS20225	COG0247	lactate metabolic process
EGY05_RS20235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGY05_RS20240	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EGY05_RS20260	COG1960	acyl-CoA dehydrogenase activity
EGY05_RS20300	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EGY05_RS20305	COG0602	queuosine metabolic process
EGY05_RS20315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGY05_RS20320	COG1127	ABC transporter
EGY05_RS20345	COG1703	isobutyryl-CoA mutase activity
EGY05_RS20370	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EGY05_RS20380	COG1690	Belongs to the RtcB family
EGY05_RS20395	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGY05_RS20395	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGY05_RS20405	COG1505	serine-type exopeptidase activity
EGY05_RS20415	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EGY05_RS20420	COG1113	amino acid transport
EGY05_RS20430	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EGY05_RS20440	COG2207	Transcriptional regulator
EGY05_RS20450	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGY05_RS20450	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EGY05_RS20475	COG1131	(ABC) transporter
EGY05_RS20485	COG0497	DNA recombination
EGY05_RS20515	COG0084	hydrolase, TatD family'
EGY05_RS20520	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGY05_RS20525	COG0594	ribonuclease P activity
EGY05_RS20550	COG3829	transcription factor binding
EGY05_RS20560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGY05_RS20575	COG0028	Belongs to the TPP enzyme family
EGY05_RS20585	COG2176	DNA-directed DNA polymerase activity
EGY05_RS20590	COG0433	COG0433 Predicted ATPase
EGY05_RS20595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGY05_RS20595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGY05_RS20605	COG3118	belongs to the thioredoxin family
EGY05_RS20620	COG0750	zinc metalloprotease
EGY05_RS20650	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EGY05_RS20655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EGY05_RS20680	COG3033	Beta-eliminating lyase
EGY05_RS20700	COG2133	pyrroloquinoline quinone binding
EGY05_RS20715	COG0556	nucleotide-excision repair
EGY05_RS20720	COG3530	Putative quorum-sensing-regulated virulence factor
EGY05_RS20745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGY05_RS20750	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EGY05_RS20825	COG0653	protein targeting
EGY05_RS20850	COG1940	carbohydrate kinase activity
EGY05_RS20855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGY05_RS20895	COG3422	double-strand break repair
EGY05_RS20935	COG2153	protein acetylation
EGY05_RS20940	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EGY05_RS20950	COG2001	Belongs to the MraZ family
EGY05_RS20955	COG0275	rRNA processing
EGY05_RS20965	COG0768	penicillin binding
EGY05_RS20970	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGY05_RS20980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGY05_RS20985	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EGY05_RS20995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EGY05_RS21000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGY05_RS21020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGY05_RS21025	COG1610	YqeY-like protein
EGY05_RS21065	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EGY05_RS21085	COG0745	RESPONSE REGULATOR receiver
EGY05_RS21105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGY05_RS21110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGY05_RS21125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGY05_RS21135	COG2255	four-way junction helicase activity
EGY05_RS21170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGY05_RS21180	COG2274	protein secretion by the type I secretion system
EGY05_RS21220	COG2909	trisaccharide binding
EGY05_RS21290	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EGY05_RS21295	COG0697	spore germination
EGY05_RS21305	COG0604	alcohol dehydrogenase
EGY05_RS21315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGY05_RS21355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EGY05_RS21380	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EGY05_RS21400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EGY05_RS21425	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EGY05_RS21465	COG0481	GTPase activity
EGY05_RS21490	COG1595	DNA-templated transcription, initiation
EGY05_RS21500	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EGY05_RS21505	COG0424	maF-like protein
EGY05_RS21515	COG1214	PFAM Peptidase M22, glycoprotease
EGY05_RS21520	COG4221	oxidoreductase activity
EGY05_RS21525	COG0792	nuclease activity
EGY05_RS21530	COG1619	proteins homologs of microcin C7 resistance protein MccF
EGY05_RS21540	COG0557	exoribonuclease II activity
EGY05_RS21545	COG0698	ribose 5-phosphate isomerase
EGY05_RS21550	COG0126	phosphoglycerate kinase activity
EGY05_RS21560	COG0445	tRNA wobble uridine modification
EGY05_RS21565	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EGY05_RS21575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGY05_RS21580	COG1435	thymidine kinase activity
EGY05_RS21590	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGY05_RS21600	COG1028	Short-chain dehydrogenase reductase Sdr
EGY05_RS21630	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EGY05_RS21640	COG0793	Belongs to the peptidase S41A family
EGY05_RS21645	COG2032	superoxide dismutase activity
EGY05_RS21655	COG4977	sequence-specific DNA binding
EGY05_RS21655	COG1917	Cupin 2, conserved barrel domain protein
EGY05_RS21670	COG3275	phosphorelay sensor kinase activity
EGY05_RS21695	COG3279	Response regulator of the LytR AlgR family
EGY05_RS21725	COG0482	sulfurtransferase activity
EGY05_RS21740	COG0542	response to heat
EGY05_RS21755	COG2166	iron-sulfur cluster assembly
EGY05_RS21795	COG0662	Cupin 2, conserved barrel domain protein
EGY05_RS21795	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EGY05_RS21810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGY05_RS21815	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGY05_RS21840	COG0811	peptide transport
EGY05_RS21865	COG2715	membrane protein required for spore maturation
EGY05_RS21875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EGY05_RS21885	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGY05_RS21895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGY05_RS21910	COG3781	membrane
EGY05_RS21920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGY05_RS21925	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EGY05_RS21970	COG2081	HI0933 family
EGY05_RS21980	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EGY05_RS21990	COG2814	Major facilitator Superfamily
EGY05_RS22000	COG3279	Response regulator of the LytR AlgR family
EGY05_RS22025	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGY05_RS22040	COG2151	metal-sulfur cluster biosynthetic enzyme
EGY05_RS22055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGY05_RS22105	COG4585	Histidine kinase
EGY05_RS22130	COG3279	Response regulator of the LytR AlgR family
EGY05_RS22135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGY05_RS22160	COG1595	DNA-templated transcription, initiation
EGY05_RS22195	COG0606	chelatase, subunit chli
EGY05_RS22225	COG3591	Belongs to the peptidase S1B family
EGY05_RS22250	COG3279	Response regulator of the LytR AlgR family
EGY05_RS22255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGY05_RS22295	COG0387	Pfam Sodium calcium exchanger
EGY05_RS22330	COG0758	DNA mediated transformation
EGY05_RS22350	COG0719	Fe-S assembly protein
EGY05_RS22355	COG0396	ATPase activity
EGY05_RS22360	COG2351	hydroxyisourate hydrolase activity
EGY05_RS22365	COG0719	Fe-S assembly protein
EGY05_RS22370	COG0316	Belongs to the HesB IscA family
EGY05_RS22380	COG2321	neutral zinc metallopeptidase
EGY05_RS22385	COG1368	sulfuric ester hydrolase activity
EGY05_RS22390	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EGY05_RS22435	COG0437	4 iron, 4 sulfur cluster binding
EGY05_RS22460	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EGY05_RS22465	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EGY05_RS22475	COG1774	PSP1 C-terminal conserved region
EGY05_RS22490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGY05_RS22495	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EGY05_RS22510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EGY05_RS22525	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EGY05_RS22550	COG0772	Belongs to the SEDS family
EGY05_RS22560	COG0791	NLP P60 protein
EGY05_RS22610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGY05_RS22630	COG0590	tRNA wobble adenosine to inosine editing
EGY05_RS22665	COG3621	Patatin-like phospholipase
EGY05_RS22670	COG1876	peptidase activity
EGY05_RS22710	COG0423	glycine-tRNA ligase activity
EGY05_RS22715	COG2382	esterase
EGY05_RS22720	COG0564	pseudouridine synthase activity
EGY05_RS22725	COG0167	dihydroorotate dehydrogenase activity
EGY05_RS22735	COG2733	membrane
EGY05_RS22740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGY05_RS22760	COG0183	Belongs to the thiolase family
EGY05_RS22770	COG1764	response to oxidative stress
EGY05_RS22775	COG0662	Cupin 2, conserved barrel domain protein
EGY05_RS22775	COG2207	Transcriptional regulator
EGY05_RS22780	COG2169	Transcriptional regulator
EGY05_RS22785	COG4771	TonB-dependent receptor
EGY05_RS22800	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EGY05_RS22890	COG1770	oligopeptidase
EGY05_RS22915	COG0463	Glycosyl transferase, family 2
EGY05_RS22925	COG0343	queuine tRNA-ribosyltransferase activity
EGY05_RS22940	COG0799	negative regulation of ribosome biogenesis
EGY05_RS22945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGY05_RS22955	COG0575	Belongs to the CDS family
EGY05_RS22960	COG0688	phosphatidylethanolamine metabolic process
EGY05_RS22980	COG1132	(ABC) transporter
EGY05_RS23030	COG1611	Belongs to the LOG family
EGY05_RS23035	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EGY05_RS23065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EGY05_RS23070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGY05_RS23100	COG0778	Nitroreductase
EGY05_RS23115	COG0328	RNA-DNA hybrid ribonuclease activity
EGY05_RS23120	COG0305	Participates in initiation and elongation during chromosome replication
EGY05_RS23160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGY05_RS23185	COG0193	aminoacyl-tRNA hydrolase activity
EGY05_RS23195	COG0659	secondary active sulfate transmembrane transporter activity
EGY05_RS23205	COG0288	reversible hydration of carbon dioxide
EGY05_RS23225	COG2194	sulfuric ester hydrolase activity
EGY05_RS23230	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EGY05_RS23245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGY05_RS23260	COG0438	transferase activity, transferring glycosyl groups
EGY05_RS23265	COG1215	transferase activity, transferring glycosyl groups
EGY05_RS23280	COG0463	Glycosyl transferase, family 2
EGY05_RS23285	COG1216	Glycosyl transferase, family 2
EGY05_RS23290	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EGY05_RS23295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGY05_RS23305	COG1216	Glycosyl transferase, family 2
EGY05_RS23320	COG3754	Rhamnan synthesis protein F
EGY05_RS23325	COG1442	glycosyl transferase family 8
EGY05_RS23325	COG1216	Glycosyl transferase, family 2
EGY05_RS23330	COG1216	Glycosyl transferase, family 2
EGY05_RS23385	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EGY05_RS23390	COG0779	Required for maturation of 30S ribosomal subunits
EGY05_RS23395	COG0195	Participates in both transcription termination and antitermination
EGY05_RS23400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EGY05_RS23410	COG1629	transport
EGY05_RS23410	COG4206	TonB-dependent receptor
EGY05_RS23425	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EGY05_RS23445	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EGY05_RS23455	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EGY05_RS23460	COG4771	TonB-dependent receptor
EGY05_RS23510	COG3781	membrane
EGY05_RS23525	COG2217	Heavy metal translocating P-type atpase
EGY05_RS23540	COG1999	signal sequence binding
EGY05_RS23545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGY05_RS23620	COG0268	Binds directly to 16S ribosomal RNA
EGY05_RS23645	COG0251	oxidation-reduction process
EGY05_RS23655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGY05_RS23660	COG1054	Belongs to the UPF0176 family
EGY05_RS23685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGY05_RS23715	COG0745	RESPONSE REGULATOR receiver
EGY05_RS23750	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EGY05_RS23755	COG0783	Belongs to the Dps family
EGY05_RS23765	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EGY05_RS23770	COG0049	tRNA binding
EGY05_RS23775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EGY05_RS23780	COG0051	transcription antitermination factor activity, RNA binding
EGY05_RS23790	COG4774	siderophore transport
EGY05_RS23855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGY05_RS23860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGY05_RS23870	COG1349	DNA-binding transcription factor activity
EGY05_RS23885	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EGY05_RS23890	COG0088	Forms part of the polypeptide exit tunnel
EGY05_RS23900	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EGY05_RS23905	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EGY05_RS23910	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EGY05_RS23915	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EGY05_RS23920	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EGY05_RS23925	COG0255	Belongs to the universal ribosomal protein uL29 family
EGY05_RS23930	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGY05_RS23935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EGY05_RS23945	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EGY05_RS23950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EGY05_RS23955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EGY05_RS23960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EGY05_RS23965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EGY05_RS23970	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EGY05_RS23975	COG1841	ribosomal large subunit assembly
EGY05_RS23980	COG0200	Binds to the 23S rRNA
EGY05_RS23990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EGY05_RS23995	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGY05_RS24000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EGY05_RS24005	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EGY05_RS24010	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EGY05_RS24015	COG0202	RNA polymerase activity
EGY05_RS24020	COG0203	ribosomal protein L17
EGY05_RS24025	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGY05_RS24040	COG2197	response regulator
EGY05_RS24055	COG4585	Histidine kinase
EGY05_RS24065	COG0148	phosphopyruvate hydratase activity
EGY05_RS24075	COG2382	esterase
EGY05_RS24075	COG3693	PFAM glycoside hydrolase, family 10
EGY05_RS24100	COG1834	amidinotransferase
EGY05_RS24115	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EGY05_RS24165	COG0085	RNA polymerase activity
EGY05_RS24175	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EGY05_RS24180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGY05_RS24180	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EGY05_RS24185	COG0501	Belongs to the peptidase M48B family
EGY05_RS24190	COG0488	(ABC) transporter
EGY05_RS24195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EGY05_RS24200	COG2885	chlorophyll binding