locus-tag	class	description
CJF12_RS00045	COG0358	DNA primase activity
CJF12_RS00050	COG4974	Belongs to the 'phage' integrase family
CJF12_RS00080	COG0358	DNA primase activity
CJF12_RS00085	COG4974	Belongs to the 'phage' integrase family
CJF12_RS00120	COG0358	DNA primase activity
CJF12_RS00140	COG4974	Belongs to the 'phage' integrase family
CJF12_RS00175	COG0358	DNA primase activity
CJF12_RS00180	COG4974	Belongs to the 'phage' integrase family
CJF12_RS00240	COG0527	aspartate kinase activity
CJF12_RS00245	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CJF12_RS00260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJF12_RS00275	COG0492	ferredoxin-NADP+ reductase activity
CJF12_RS00325	COG0714	Associated with various cellular activities
CJF12_RS00345	COG2304	oxidoreductase activity
CJF12_RS00350	COG2304	oxidoreductase activity
CJF12_RS00365	COG2095	MarC family integral membrane protein
CJF12_RS00375	COG1169	isochorismate synthase
CJF12_RS00380	COG2050	protein possibly involved in aromatic compounds catabolism
CJF12_RS00415	COG1607	acyl-coa hydrolase
CJF12_RS00425	COG1193	negative regulation of DNA recombination
CJF12_RS00430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJF12_RS00455	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CJF12_RS00460	COG2267	carboxylic ester hydrolase activity
CJF12_RS00490	COG1022	Amp-dependent synthetase and ligase
CJF12_RS00520	COG0730	response to heat
CJF12_RS00530	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CJF12_RS00540	COG0589	response to stress
CJF12_RS00540	COG0475	glutathione-regulated potassium exporter activity
CJF12_RS00550	COG0697	spore germination
CJF12_RS00570	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CJF12_RS00600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CJF12_RS00650	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS00660	COG1764	response to oxidative stress
CJF12_RS00670	COG1309	transcriptional regulator
CJF12_RS00685	COG2814	Major facilitator Superfamily
CJF12_RS00700	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS00715	COG0519	Catalyzes the synthesis of GMP from XMP
CJF12_RS00720	COG1733	regulation of RNA biosynthetic process
CJF12_RS00725	COG1733	regulation of RNA biosynthetic process
CJF12_RS00730	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS00750	COG0598	Magnesium transport protein CorA
CJF12_RS00755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJF12_RS00765	COG3118	belongs to the thioredoxin family
CJF12_RS00780	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS00790	COG0831	urea catabolic process
CJF12_RS00795	COG0832	Belongs to the urease beta subunit family
CJF12_RS00800	COG0804	urea catabolic process
CJF12_RS00810	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CJF12_RS00820	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CJF12_RS00825	COG0829	nickel cation binding
CJF12_RS00865	COG0006	proline dipeptidase activity
CJF12_RS00870	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CJF12_RS00890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJF12_RS00895	COG2207	Transcriptional regulator
CJF12_RS00930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJF12_RS00980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CJF12_RS01060	COG2197	response regulator
CJF12_RS01100	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CJF12_RS01120	COG2207	Transcriptional regulator
CJF12_RS01120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJF12_RS01140	COG4106	trans-aconitate 2-methyltransferase activity
CJF12_RS01145	COG1522	sequence-specific DNA binding
CJF12_RS01150	COG0477	Major facilitator Superfamily
CJF12_RS01160	COG1611	Belongs to the LOG family
CJF12_RS01170	COG2807	transmembrane transport
CJF12_RS01175	COG1472	Belongs to the glycosyl hydrolase 3 family
CJF12_RS01180	COG1464	Belongs to the NlpA lipoprotein family
CJF12_RS01185	COG2011	ABC-type metal ion transport system permease component
CJF12_RS01190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CJF12_RS01220	COG0738	Major facilitator superfamily
CJF12_RS01225	COG0246	Mannitol dehydrogenase
CJF12_RS01230	COG1609	Transcriptional regulator
CJF12_RS01245	COG4771	TonB-dependent receptor
CJF12_RS01250	COG0702	epimerase
CJF12_RS01255	COG0584	glycerophosphoryl diester phosphodiesterase
CJF12_RS01265	COG1950	PFAM Membrane protein of
CJF12_RS01270	COG1506	peptidase
CJF12_RS01270	COG0823	Involved in the tonB-independent uptake of proteins
CJF12_RS01285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CJF12_RS01290	COG0673	inositol 2-dehydrogenase activity
CJF12_RS01305	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CJF12_RS01310	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CJF12_RS01325	COG0142	geranyltranstransferase activity
CJF12_RS01335	COG0022	dehydrogenase e1 component
CJF12_RS01435	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CJF12_RS01440	COG1131	(ABC) transporter
CJF12_RS01485	COG2267	carboxylic ester hydrolase activity
CJF12_RS01490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJF12_RS01495	COG4221	oxidoreductase activity
CJF12_RS01495	COG3321	synthase
CJF12_RS01495	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS01495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJF12_RS01500	COG0604	alcohol dehydrogenase
CJF12_RS01500	COG3321	synthase
CJF12_RS01560	COG4584	PFAM Integrase catalytic
CJF12_RS01565	COG1484	DNA-dependent DNA replication
CJF12_RS01570	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CJF12_RS01605	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJF12_RS01625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJF12_RS01645	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CJF12_RS01660	COG4574	serine-type endopeptidase inhibitor activity
CJF12_RS01670	COG2274	protein secretion by the type I secretion system
CJF12_RS01690	COG1505	serine-type exopeptidase activity
CJF12_RS01695	COG1770	oligopeptidase
CJF12_RS01760	COG3781	membrane
CJF12_RS01765	COG0025	NhaP-type Na H and K H
CJF12_RS01795	COG1428	Deoxynucleoside kinase
CJF12_RS01800	COG1393	Belongs to the ArsC family
CJF12_RS01815	COG1629	transport
CJF12_RS01820	COG0702	epimerase
CJF12_RS01855	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJF12_RS01890	COG0592	DNA-directed DNA polymerase activity
CJF12_RS01915	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJF12_RS01950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CJF12_RS01990	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS02005	COG3059	membrane
CJF12_RS02010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJF12_RS02010	COG2207	Transcriptional regulator
CJF12_RS02035	COG0667	Aldo Keto reductase
CJF12_RS02055	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CJF12_RS02060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJF12_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS02175	COG1191	sigma factor activity
CJF12_RS02190	COG0484	heat shock protein binding
CJF12_RS02210	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJF12_RS02210	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJF12_RS02245	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CJF12_RS02265	COG0531	amino acid
CJF12_RS02315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CJF12_RS02320	COG0363	glucosamine-6-phosphate deaminase activity
CJF12_RS02330	COG1473	amidohydrolase
CJF12_RS02335	COG2706	6-phosphogluconolactonase activity
CJF12_RS02340	COG3119	arylsulfatase activity
CJF12_RS02345	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CJF12_RS02350	COG3119	arylsulfatase activity
CJF12_RS02355	COG1335	isochorismatase
CJF12_RS02365	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS02370	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS02375	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS02405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CJF12_RS02430	COG2183	response to ionizing radiation
CJF12_RS02455	COG0693	protein deglycase activity
CJF12_RS02470	COG1649	PFAM Uncharacterised BCR, COG1649
CJF12_RS02480	COG1528	Iron-storage protein
CJF12_RS02485	COG0012	GTP binding
CJF12_RS02495	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS02505	COG0436	Aminotransferase
CJF12_RS02515	COG3279	Response regulator of the LytR AlgR family
CJF12_RS02520	COG2972	Histidine kinase
CJF12_RS02525	COG3292	Two component regulator propeller
CJF12_RS02525	COG2205	protein histidine kinase activity
CJF12_RS02525	COG0745	RESPONSE REGULATOR receiver
CJF12_RS02550	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS02555	COG1090	epimerase
CJF12_RS02575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJF12_RS02585	COG2890	protein-(glutamine-N5) methyltransferase activity
CJF12_RS02590	COG3022	response to hydroperoxide
CJF12_RS02595	COG0009	L-threonylcarbamoyladenylate synthase
CJF12_RS02645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CJF12_RS02660	COG3340	Belongs to the peptidase S51 family
CJF12_RS02670	COG3852	Histidine kinase
CJF12_RS02695	COG0805	protein transport
CJF12_RS02710	COG0517	IMP dehydrogenase activity
CJF12_RS02710	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CJF12_RS02715	COG0514	ATP-dependent DNA helicase (RecQ)
CJF12_RS02720	COG0438	transferase activity, transferring glycosyl groups
CJF12_RS02725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJF12_RS02740	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS02745	COG2996	Protein conserved in bacteria
CJF12_RS02760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJF12_RS02770	COG0484	heat shock protein binding
CJF12_RS02775	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CJF12_RS02790	COG0494	nUDIX hydrolase
CJF12_RS02800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CJF12_RS02805	COG1090	epimerase
CJF12_RS02820	COG1942	4-Oxalocrotonate Tautomerase
CJF12_RS02840	COG0629	single-stranded DNA binding
CJF12_RS02850	COG0124	histidyl-tRNA synthetase
CJF12_RS02855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CJF12_RS02860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CJF12_RS02870	COG1446	asparaginase
CJF12_RS02875	COG4242	Belongs to the peptidase S51 family
CJF12_RS02900	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CJF12_RS02920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CJF12_RS02930	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CJF12_RS02935	COG0297	glycogen (starch) synthase activity
CJF12_RS02940	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CJF12_RS02955	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJF12_RS02960	COG2967	ApaG domain
CJF12_RS02965	COG2176	DNA-directed DNA polymerase activity
CJF12_RS02970	COG0463	Glycosyl transferase, family 2
CJF12_RS02990	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS03015	COG0359	binds to the 23S rRNA
CJF12_RS03020	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CJF12_RS03025	COG0360	Binds together with S18 to 16S ribosomal RNA
CJF12_RS03040	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJF12_RS03050	COG1702	phosphate starvation-inducible protein PhoH
CJF12_RS03075	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CJF12_RS03085	COG0356	it plays a direct role in the translocation of protons across the membrane
CJF12_RS03090	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJF12_RS03095	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CJF12_RS03100	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJF12_RS03105	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CJF12_RS03110	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CJF12_RS03115	COG1253	flavin adenine dinucleotide binding
CJF12_RS03140	COG0572	uridine kinase
CJF12_RS03150	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJF12_RS03150	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJF12_RS03180	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS03190	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CJF12_RS03200	COG2211	Major facilitator Superfamily
CJF12_RS03215	COG0183	Belongs to the thiolase family
CJF12_RS03220	COG2270	Major facilitator Superfamily
CJF12_RS03260	COG0531	amino acid
CJF12_RS03295	COG2323	membrane
CJF12_RS03340	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CJF12_RS03355	COG0463	Glycosyl transferase, family 2
CJF12_RS03375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CJF12_RS03390	COG3813	Protein conserved in bacteria
CJF12_RS03395	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CJF12_RS03405	COG0386	Belongs to the glutathione peroxidase family
CJF12_RS03435	COG0196	riboflavin kinase activity
CJF12_RS03440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CJF12_RS03445	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CJF12_RS03465	COG0156	8-amino-7-oxononanoate synthase activity
CJF12_RS03500	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CJF12_RS03525	COG2132	Multicopper oxidase
CJF12_RS03545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CJF12_RS03585	COG1321	iron dependent repressor
CJF12_RS03630	COG0640	Transcriptional regulator
CJF12_RS03640	COG0671	phosphoesterase, PA-phosphatase related
CJF12_RS03670	COG1252	NADH dehydrogenase
CJF12_RS03680	COG3275	phosphorelay sensor kinase activity
CJF12_RS03695	COG1484	DNA-dependent DNA replication
CJF12_RS03700	COG4584	PFAM Integrase catalytic
CJF12_RS03725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJF12_RS03760	COG1648	precorrin-2 dehydrogenase activity
CJF12_RS03760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CJF12_RS03770	COG1045	serine acetyltransferase
CJF12_RS03785	COG0175	sulfate reduction
CJF12_RS03790	COG1959	2 iron, 2 sulfur cluster binding
CJF12_RS03815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJF12_RS03830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJF12_RS03840	COG0006	proline dipeptidase activity
CJF12_RS03845	COG0823	Involved in the tonB-independent uptake of proteins
CJF12_RS03845	COG4946	Tricorn protease homolog
CJF12_RS03845	COG1506	peptidase
CJF12_RS03850	COG2094	Belongs to the DNA glycosylase MPG family
CJF12_RS03855	COG3663	DNA glycosylase
CJF12_RS03860	COG2076	Multidrug Resistance protein
CJF12_RS03885	COG3279	Response regulator of the LytR AlgR family
CJF12_RS03890	COG3275	phosphorelay sensor kinase activity
CJF12_RS03895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJF12_RS03905	COG2814	Major facilitator Superfamily
CJF12_RS03930	COG1349	DNA-binding transcription factor activity
CJF12_RS03935	COG2223	nitrite transmembrane transporter activity
CJF12_RS03940	COG0346	lactoylglutathione lyase activity
CJF12_RS03960	COG1285	pathogenesis
CJF12_RS03965	COG0671	phosphoesterase, PA-phosphatase related
CJF12_RS03975	COG4771	TonB-dependent receptor
CJF12_RS03990	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS04005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CJF12_RS04010	COG0667	Aldo Keto reductase
CJF12_RS04015	COG1058	Belongs to the CinA family
CJF12_RS04015	COG1546	Belongs to the CinA family
CJF12_RS04020	COG3685	Protein conserved in bacteria
CJF12_RS04050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJF12_RS04055	COG3279	Response regulator of the LytR AlgR family
CJF12_RS04075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJF12_RS04085	COG0183	Belongs to the thiolase family
CJF12_RS04130	COG3275	phosphorelay sensor kinase activity
CJF12_RS04165	COG1285	pathogenesis
CJF12_RS04170	COG5002	protein histidine kinase activity
CJF12_RS04175	COG0745	RESPONSE REGULATOR receiver
CJF12_RS04195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJF12_RS04200	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CJF12_RS04205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CJF12_RS04210	COG0156	8-amino-7-oxononanoate synthase activity
CJF12_RS04220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJF12_RS04235	COG0076	glutamate decarboxylase activity
CJF12_RS04245	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CJF12_RS04255	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CJF12_RS04260	COG1733	regulation of RNA biosynthetic process
CJF12_RS04265	COG2084	Dehydrogenase
CJF12_RS04270	COG2084	Dehydrogenase
CJF12_RS04275	COG2814	Major facilitator Superfamily
CJF12_RS04285	COG0667	Aldo Keto reductase
CJF12_RS04290	COG2084	Dehydrogenase
CJF12_RS04300	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CJF12_RS04305	COG1609	Transcriptional regulator
CJF12_RS04310	COG2271	Major facilitator Superfamily
CJF12_RS04315	COG1904	glucuronate isomerase
CJF12_RS04320	COG1312	Catalyzes the dehydration of D-mannonate
CJF12_RS04325	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS04340	COG3250	beta-galactosidase activity
CJF12_RS04355	COG1629	transport
CJF12_RS04360	COG0702	epimerase
CJF12_RS04365	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CJF12_RS04375	COG5492	domain, Protein
CJF12_RS04380	COG3250	beta-galactosidase activity
CJF12_RS04390	COG0300	oxidoreductase activity
CJF12_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS04425	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CJF12_RS04425	COG1793	dna ligase
CJF12_RS04430	COG1793	dna ligase
CJF12_RS04460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJF12_RS04485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJF12_RS04500	COG0025	NhaP-type Na H and K H
CJF12_RS04615	COG3871	stress protein (general stress protein 26)
CJF12_RS04645	COG0671	phosphoesterase, PA-phosphatase related
CJF12_RS04670	COG5002	protein histidine kinase activity
CJF12_RS04675	COG0745	RESPONSE REGULATOR receiver
CJF12_RS04680	COG1058	Belongs to the CinA family
CJF12_RS04680	COG1546	Belongs to the CinA family
CJF12_RS04685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJF12_RS04695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJF12_RS04715	COG2318	DinB family
CJF12_RS04720	COG0513	Belongs to the DEAD box helicase family
CJF12_RS04725	COG1335	isochorismatase
CJF12_RS04730	COG1187	pseudouridine synthase activity
CJF12_RS04735	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CJF12_RS04765	COG0584	glycerophosphoryl diester phosphodiesterase
CJF12_RS04770	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CJF12_RS04790	COG2356	endonuclease I
CJF12_RS04795	COG1960	acyl-CoA dehydrogenase activity
CJF12_RS04830	COG0473	3-isopropylmalate dehydrogenase activity
CJF12_RS04835	COG0066	3-isopropylmalate dehydratase activity
CJF12_RS04840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CJF12_RS04845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJF12_RS04865	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CJF12_RS04870	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CJF12_RS04890	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CJF12_RS04895	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CJF12_RS04900	COG2234	aminopeptidase activity
CJF12_RS04905	COG2234	aminopeptidase activity
CJF12_RS04950	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CJF12_RS04950	COG0140	phosphoribosyl-ATP diphosphatase activity
CJF12_RS04955	COG0107	imidazoleglycerol-phosphate synthase activity
CJF12_RS04960	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CJF12_RS04970	COG0131	Imidazoleglycerol-phosphate dehydratase
CJF12_RS04975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CJF12_RS04980	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CJF12_RS04985	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CJF12_RS04995	COG0438	transferase activity, transferring glycosyl groups
CJF12_RS05005	COG0463	Glycosyl transferase, family 2
CJF12_RS05015	COG2171	N-acyltransferase activity
CJF12_RS05045	COG0791	NLP P60 protein
CJF12_RS05075	COG1484	DNA-dependent DNA replication
CJF12_RS05080	COG4584	PFAM Integrase catalytic
CJF12_RS05135	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS05160	COG1333	cytochrome c biogenesis protein
CJF12_RS05160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CJF12_RS05165	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CJF12_RS05190	COG1674	ftsk spoiiie
CJF12_RS05205	COG0233	cytoplasmic translational termination
CJF12_RS05210	COG0528	UMP kinase activity
CJF12_RS05240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJF12_RS05250	COG2949	membrane
CJF12_RS05255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CJF12_RS05260	COG3118	belongs to the thioredoxin family
CJF12_RS05275	COG1120	ATPase activity
CJF12_RS05285	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJF12_RS05285	COG1024	Enoyl-CoA hydratase
CJF12_RS05295	COG0183	Belongs to the thiolase family
CJF12_RS05300	COG1960	acyl-CoA dehydrogenase activity
CJF12_RS05305	COG3422	double-strand break repair
CJF12_RS05325	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CJF12_RS05380	COG1088	dTDP-glucose 4,6-dehydratase activity
CJF12_RS05390	COG1349	DNA-binding transcription factor activity
CJF12_RS05400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CJF12_RS05405	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CJF12_RS05415	COG0028	Belongs to the TPP enzyme family
CJF12_RS05420	COG0129	dihydroxy-acid dehydratase activity
CJF12_RS05435	COG2234	aminopeptidase activity
CJF12_RS05445	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CJF12_RS05455	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CJF12_RS05475	COG2003	Belongs to the UPF0758 family
CJF12_RS05480	COG1136	(ABC) transporter
CJF12_RS05510	COG0724	RNA recognition motif
CJF12_RS05515	COG1607	acyl-coa hydrolase
CJF12_RS05525	COG2217	Heavy metal translocating P-type atpase
CJF12_RS05535	COG0726	polysaccharide deacetylase
CJF12_RS05545	COG2204	response regulator
CJF12_RS05550	COG0534	Mate efflux family protein
CJF12_RS05565	COG1506	peptidase
CJF12_RS05575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CJF12_RS05595	COG2076	Multidrug Resistance protein
CJF12_RS05600	COG2226	methyltransferase
CJF12_RS05620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CJF12_RS05650	COG0813	purine-nucleoside phosphorylase activity
CJF12_RS05660	COG0519	Catalyzes the synthesis of GMP from XMP
CJF12_RS05670	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CJF12_RS05695	COG4771	TonB-dependent receptor
CJF12_RS05710	COG1960	acyl-CoA dehydrogenase activity
CJF12_RS05745	COG0357	Ribosomal RNA small subunit methyltransferase G
CJF12_RS05750	COG2234	aminopeptidase activity
CJF12_RS05755	COG0436	Aminotransferase
CJF12_RS05760	COG0612	Peptidase, M16
CJF12_RS05765	COG0450	alkyl hydroperoxide reductase
CJF12_RS05770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJF12_RS05820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CJF12_RS05825	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CJF12_RS05830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJF12_RS05870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CJF12_RS05880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CJF12_RS05885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJF12_RS05885	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CJF12_RS05900	COG1363	Peptidase, m42
CJF12_RS05905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CJF12_RS05920	COG0105	UTP biosynthetic process
CJF12_RS05925	COG2814	Major facilitator Superfamily
CJF12_RS05935	COG1162	GTPase activity
CJF12_RS05940	COG1605	Chorismate mutase
CJF12_RS05940	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CJF12_RS05960	COG0156	8-amino-7-oxononanoate synthase activity
CJF12_RS06005	COG0025	NhaP-type Na H and K H
CJF12_RS06010	COG2814	Major facilitator Superfamily
CJF12_RS06020	COG1785	Belongs to the alkaline phosphatase family
CJF12_RS06040	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CJF12_RS06045	COG1174	glycine betaine transport
CJF12_RS06050	COG0517	IMP dehydrogenase activity
CJF12_RS06050	COG1125	glycine betaine transport
CJF12_RS06055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CJF12_RS06105	COG3781	membrane
CJF12_RS06150	COG1733	regulation of RNA biosynthetic process
CJF12_RS06155	COG1902	pentaerythritol trinitrate reductase activity
CJF12_RS06190	COG1917	Cupin 2, conserved barrel domain protein
CJF12_RS06190	COG2207	Transcriptional regulator
CJF12_RS06200	COG0303	'Molybdopterin
CJF12_RS06205	COG0315	cyclic pyranopterin monophosphate synthase activity
CJF12_RS06210	COG0746	molybdenum cofactor guanylyltransferase activity
CJF12_RS06215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CJF12_RS06225	COG3781	membrane
CJF12_RS06230	COG2223	nitrite transmembrane transporter activity
CJF12_RS06250	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CJF12_RS06255	COG0314	molybdopterin synthase activity
CJF12_RS06275	COG4221	oxidoreductase activity
CJF12_RS06285	COG4584	PFAM Integrase catalytic
CJF12_RS06290	COG1484	DNA-dependent DNA replication
CJF12_RS06360	COG0784	Response regulator, receiver
CJF12_RS06360	COG2205	protein histidine kinase activity
CJF12_RS06370	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CJF12_RS06375	COG3437	response regulator, receiver
CJF12_RS06385	COG5002	protein histidine kinase activity
CJF12_RS06390	COG2318	DinB family
CJF12_RS06405	COG0431	NADPH-dependent FMN reductase
CJF12_RS06410	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CJF12_RS06420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJF12_RS06480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CJF12_RS06510	COG4771	TonB-dependent receptor
CJF12_RS06540	COG1733	regulation of RNA biosynthetic process
CJF12_RS06550	COG0667	Aldo Keto reductase
CJF12_RS06590	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CJF12_RS06605	COG1077	Cell shape determining protein MreB Mrl
CJF12_RS06610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CJF12_RS06625	COG0492	ferredoxin-NADP+ reductase activity
CJF12_RS06640	COG1011	Hydrolase
CJF12_RS06670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJF12_RS06670	COG2169	Transcriptional regulator
CJF12_RS06710	COG0540	Belongs to the ATCase OTCase family
CJF12_RS06715	COG1522	sequence-specific DNA binding
CJF12_RS06720	COG0165	Argininosuccinate lyase
CJF12_RS06725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJF12_RS06730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CJF12_RS06740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJF12_RS06745	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CJF12_RS06750	COG0137	argininosuccinate synthase activity
CJF12_RS06790	COG0745	RESPONSE REGULATOR receiver
CJF12_RS06800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJF12_RS06810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CJF12_RS06830	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CJF12_RS06840	COG0671	phosphoesterase, PA-phosphatase related
CJF12_RS06845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJF12_RS06860	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJF12_RS06860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJF12_RS06865	COG2133	pyrroloquinoline quinone binding
CJF12_RS06875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJF12_RS06890	COG0531	amino acid
CJF12_RS06905	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CJF12_RS06910	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CJF12_RS06925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJF12_RS06960	COG1733	regulation of RNA biosynthetic process
CJF12_RS06965	COG1979	alcohol dehydrogenase
CJF12_RS06980	COG0513	Belongs to the DEAD box helicase family
CJF12_RS06990	COG3153	acetyltransferase
CJF12_RS06990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJF12_RS07020	COG0519	Catalyzes the synthesis of GMP from XMP
CJF12_RS07020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CJF12_RS07025	COG0151	Belongs to the GarS family
CJF12_RS07035	COG2267	carboxylic ester hydrolase activity
CJF12_RS07040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CJF12_RS07045	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CJF12_RS07055	COG1741	Belongs to the pirin family
CJF12_RS07070	COG0366	Alpha amylase catalytic
CJF12_RS07075	COG1082	Xylose isomerase domain protein TIM barrel
CJF12_RS07085	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CJF12_RS07090	COG1629	transport
CJF12_RS07090	COG4206	TonB-dependent receptor
CJF12_RS07095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJF12_RS07095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJF12_RS07155	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CJF12_RS07160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJF12_RS07165	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CJF12_RS07175	COG0077	Prephenate dehydratase
CJF12_RS07200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CJF12_RS07205	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CJF12_RS07210	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CJF12_RS07210	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CJF12_RS07215	COG1970	mechanosensitive ion channel activity
CJF12_RS07220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJF12_RS07230	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CJF12_RS07240	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CJF12_RS07260	COG1607	acyl-coa hydrolase
CJF12_RS07270	COG0038	chloride channel
CJF12_RS07280	COG2855	membrane
CJF12_RS07290	COG0477	Major facilitator Superfamily
CJF12_RS07295	COG1418	mRNA catabolic process
CJF12_RS07315	COG2226	methyltransferase
CJF12_RS07325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJF12_RS07330	COG1408	metallophosphoesterase
CJF12_RS07335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CJF12_RS07345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJF12_RS07360	COG0405	Gamma-glutamyltransferase
CJF12_RS07365	COG1301	dicarboxylic acid transport
CJF12_RS07395	COG0187	DNA topoisomerase II activity
CJF12_RS07415	COG0067	glutamate synthase
CJF12_RS07415	COG0069	glutamate synthase activity
CJF12_RS07415	COG0070	glutamate synthase
CJF12_RS07420	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CJF12_RS07425	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CJF12_RS07430	COG4654	Cytochrome c, class I
CJF12_RS07445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CJF12_RS07450	COG0512	Glutamine amidotransferase of anthranilate synthase
CJF12_RS07450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJF12_RS07455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJF12_RS07465	COG0134	indole-3-glycerol-phosphate synthase activity
CJF12_RS07485	COG0133	tryptophan synthase activity
CJF12_RS07490	COG0159	tryptophan synthase activity
CJF12_RS07495	COG0321	lipoyl(octanoyl) transferase activity
CJF12_RS07530	COG0778	Nitroreductase
CJF12_RS07535	COG1846	Transcriptional regulator
CJF12_RS07540	COG0242	peptide deformylase activity
CJF12_RS07555	COG3720	iron ion transport
CJF12_RS07570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJF12_RS07615	COG1959	2 iron, 2 sulfur cluster binding
CJF12_RS07650	COG1981	membrane
CJF12_RS07660	COG0156	8-amino-7-oxononanoate synthase activity
CJF12_RS07675	COG2027	D-alanyl-D-alanine carboxypeptidase
CJF12_RS07680	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CJF12_RS07690	COG0679	Auxin Efflux Carrier
CJF12_RS07700	COG3250	beta-galactosidase activity
CJF12_RS07710	COG3142	Participates in the control of copper homeostasis
CJF12_RS07715	COG1446	asparaginase
CJF12_RS07720	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CJF12_RS07745	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CJF12_RS07770	COG0335	large ribosomal subunit rRNA binding
CJF12_RS07775	COG2207	Transcriptional regulator
CJF12_RS07780	COG2814	Major facilitator Superfamily
CJF12_RS07800	COG0539	negative regulation of cytoplasmic translation
CJF12_RS07800	COG2183	response to ionizing radiation
CJF12_RS07805	COG0513	Belongs to the DEAD box helicase family
CJF12_RS07815	COG0348	domain, Protein
CJF12_RS07840	COG1187	pseudouridine synthase activity
CJF12_RS07845	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CJF12_RS07850	COG1968	undecaprenyl-diphosphatase activity
CJF12_RS07860	COG2177	Part of the ABC transporter FtsEX involved in
CJF12_RS07865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CJF12_RS07895	COG1234	tRNA 3'-trailer cleavage
CJF12_RS07900	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CJF12_RS07955	COG1960	acyl-CoA dehydrogenase activity
CJF12_RS07960	COG1022	Amp-dependent synthetase and ligase
CJF12_RS07970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CJF12_RS07975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJF12_RS07995	COG0587	DNA-directed DNA polymerase activity
CJF12_RS08000	COG0022	dehydrogenase e1 component
CJF12_RS08005	COG3781	membrane
CJF12_RS08010	COG1522	sequence-specific DNA binding
CJF12_RS08015	COG0626	cystathionine gamma-synthase activity
CJF12_RS08045	COG0116	Belongs to the methyltransferase superfamily
CJF12_RS08060	COG4771	TonB-dependent receptor
CJF12_RS08065	COG0702	epimerase
CJF12_RS08080	COG0442	prolyl-tRNA aminoacylation
CJF12_RS08090	COG1914	H( )-stimulated, divalent metal cation uptake system
CJF12_RS08095	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CJF12_RS08100	COG0484	heat shock protein binding
CJF12_RS08110	COG2354	Protein conserved in bacteria
CJF12_RS08125	COG0586	Pfam SNARE associated Golgi protein
CJF12_RS08130	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CJF12_RS08135	COG2072	flavoprotein involved in K transport
CJF12_RS08145	COG1131	(ABC) transporter
CJF12_RS08175	COG1595	DNA-templated transcription, initiation
CJF12_RS08180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CJF12_RS08205	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CJF12_RS08225	COG0149	triose-phosphate isomerase activity
CJF12_RS08240	COG0358	DNA primase activity
CJF12_RS08245	COG0802	atpase or kinase
CJF12_RS08275	COG0475	glutathione-regulated potassium exporter activity
CJF12_RS08285	COG0287	Prephenate dehydrogenase
CJF12_RS08290	COG1760	l-serine dehydratase
CJF12_RS08315	COG0837	glucose binding
CJF12_RS08340	COG1185	polyribonucleotide nucleotidyltransferase activity
CJF12_RS08350	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CJF12_RS08360	COG2239	Acts as a magnesium transporter
CJF12_RS08365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJF12_RS08380	COG0321	lipoyl(octanoyl) transferase activity
CJF12_RS08380	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CJF12_RS08390	COG4771	TonB-dependent receptor
CJF12_RS08400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJF12_RS08405	COG0477	Major facilitator Superfamily
CJF12_RS08410	COG1309	transcriptional regulator
CJF12_RS08435	COG2079	MmgE PrpD family protein
CJF12_RS08450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJF12_RS08465	COG0387	Pfam Sodium calcium exchanger
CJF12_RS08480	COG0513	Belongs to the DEAD box helicase family
CJF12_RS08490	COG1278	Cold shock
CJF12_RS08500	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS08515	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CJF12_RS08530	COG2267	carboxylic ester hydrolase activity
CJF12_RS08540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJF12_RS08580	COG3590	peptidase
CJF12_RS08585	COG3590	peptidase
CJF12_RS08590	COG1215	transferase activity, transferring glycosyl groups
CJF12_RS08595	COG1546	Belongs to the CinA family
CJF12_RS08595	COG1058	Belongs to the CinA family
CJF12_RS08605	COG3279	Response regulator of the LytR AlgR family
CJF12_RS08610	COG3275	phosphorelay sensor kinase activity
CJF12_RS08630	COG0723	plastoquinol--plastocyanin reductase activity
CJF12_RS08630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJF12_RS08650	COG2814	Major facilitator Superfamily
CJF12_RS08655	COG1917	Cupin 2, conserved barrel domain protein
CJF12_RS08655	COG2207	Transcriptional regulator
CJF12_RS08665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CJF12_RS08675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CJF12_RS08690	COG3409	Peptidoglycan-binding domain 1 protein
CJF12_RS08690	COG0793	Belongs to the peptidase S41A family
CJF12_RS08790	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CJF12_RS08795	COG0633	Ferredoxin
CJF12_RS08810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJF12_RS08815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJF12_RS08820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJF12_RS08875	COG1770	oligopeptidase
CJF12_RS08905	COG1104	cysteine desulfurase activity
CJF12_RS08925	COG0277	FAD linked oxidase domain protein
CJF12_RS08930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CJF12_RS08955	COG0681	Belongs to the peptidase S26 family
CJF12_RS08960	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CJF12_RS08970	COG1475	DNA binding
CJF12_RS08975	COG1192	Involved in chromosome partitioning
CJF12_RS08985	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CJF12_RS08995	COG0488	(ABC) transporter
CJF12_RS09000	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CJF12_RS09005	COG0563	adenylate kinase activity
CJF12_RS09010	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CJF12_RS09020	COG0513	Belongs to the DEAD box helicase family
CJF12_RS09025	COG0084	hydrolase, TatD family'
CJF12_RS09045	COG0306	phosphate transporter
CJF12_RS09065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJF12_RS09070	COG1136	(ABC) transporter
CJF12_RS09075	COG1136	(ABC) transporter
CJF12_RS09075	COG0577	efflux transmembrane transporter activity
CJF12_RS09105	COG1027	Aspartate ammonia-lyase
CJF12_RS09130	COG2827	Endonuclease containing a URI domain
CJF12_RS09140	COG1733	regulation of RNA biosynthetic process
CJF12_RS09160	COG3239	Fatty acid desaturase
CJF12_RS09175	COG2264	protein methyltransferase activity
CJF12_RS09180	COG0300	oxidoreductase activity
CJF12_RS09195	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CJF12_RS09210	COG4717	serine-type aminopeptidase activity
CJF12_RS09215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJF12_RS09250	COG0702	epimerase
CJF12_RS09260	COG4771	TonB-dependent receptor
CJF12_RS09265	COG0612	Peptidase, M16
CJF12_RS09275	COG2204	response regulator
CJF12_RS09280	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CJF12_RS09290	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CJF12_RS09330	COG1335	isochorismatase
CJF12_RS09365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJF12_RS09365	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJF12_RS09385	COG3501	Rhs element vgr protein
CJF12_RS09420	COG3501	Rhs element vgr protein
CJF12_RS09435	COG0542	response to heat
CJF12_RS09465	COG2197	response regulator
CJF12_RS09470	COG0776	regulation of translation
CJF12_RS09475	COG1530	ribonuclease E activity
CJF12_RS09505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CJF12_RS09530	COG2070	2-Nitropropane dioxygenase
CJF12_RS09555	COG0656	L-ascorbic acid biosynthetic process
CJF12_RS09565	COG0456	acetyltransferase
CJF12_RS09575	COG0583	DNA-binding transcription factor activity
CJF12_RS09585	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS09600	COG0667	Aldo Keto reductase
CJF12_RS09615	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CJF12_RS09640	COG4771	TonB-dependent receptor
CJF12_RS09645	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CJF12_RS09650	COG0427	acetyl-CoA hydrolase
CJF12_RS09660	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CJF12_RS09705	COG1966	Carbon starvation protein
CJF12_RS09710	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CJF12_RS09715	COG0352	thiamine-phosphate diphosphorylase activity
CJF12_RS09720	COG0352	thiamine-phosphate diphosphorylase activity
CJF12_RS09720	COG0351	phosphomethylpyrimidine kinase
CJF12_RS09725	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CJF12_RS09730	COG4771	TonB-dependent receptor
CJF12_RS09740	COG0612	Peptidase, M16
CJF12_RS09745	COG0612	Peptidase, M16
CJF12_RS09760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CJF12_RS09775	COG2195	Cleaves the N-terminal amino acid of tripeptides
CJF12_RS09785	COG0492	ferredoxin-NADP+ reductase activity
CJF12_RS09795	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CJF12_RS09805	COG3842	ATPase activity
CJF12_RS09810	COG2824	Alkylphosphonate utilization operon protein PhnA
CJF12_RS09825	COG0367	asparagine synthase
CJF12_RS09835	COG0477	Major facilitator Superfamily
CJF12_RS09850	COG1741	Belongs to the pirin family
CJF12_RS09855	COG0431	NADPH-dependent FMN reductase
CJF12_RS09875	COG2388	GCN5-related N-acetyl-transferase
CJF12_RS09880	COG4145	pantothenate transmembrane transporter activity
CJF12_RS09885	COG3959	Transketolase, thiamine diphosphate binding domain
CJF12_RS09890	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CJF12_RS09900	COG1309	transcriptional regulator
CJF12_RS09915	COG1522	sequence-specific DNA binding
CJF12_RS09925	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CJF12_RS09935	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CJF12_RS09955	COG0252	asparaginase activity
CJF12_RS09975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJF12_RS09985	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CJF12_RS10000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJF12_RS10070	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CJF12_RS10075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CJF12_RS10085	COG0297	glycogen (starch) synthase activity
CJF12_RS10090	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CJF12_RS10110	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CJF12_RS10115	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CJF12_RS10125	COG0069	glutamate synthase activity
CJF12_RS10130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJF12_RS10165	COG1506	peptidase
CJF12_RS10165	COG0823	Involved in the tonB-independent uptake of proteins
CJF12_RS10175	COG3104	oligopeptide transport
CJF12_RS10180	COG3104	oligopeptide transport
CJF12_RS10190	COG4232	protein-disulfide reductase activity
CJF12_RS10195	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CJF12_RS10215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJF12_RS10220	COG0737	Belongs to the 5'-nucleotidase family
CJF12_RS10225	COG0737	Belongs to the 5'-nucleotidase family
CJF12_RS10320	COG0579	oxidoreductase
CJF12_RS10330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJF12_RS10335	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CJF12_RS10340	COG0739	heme binding
CJF12_RS10350	COG2910	NAD(P)H-binding
CJF12_RS10390	COG3853	Toxic anion resistance protein (TelA)
CJF12_RS10400	COG0659	secondary active sulfate transmembrane transporter activity
CJF12_RS10465	COG0714	Associated with various cellular activities
CJF12_RS10480	COG0813	purine-nucleoside phosphorylase activity
CJF12_RS10495	COG1505	serine-type exopeptidase activity
CJF12_RS10535	COG1073	alpha beta
CJF12_RS10565	COG0024	Methionine aminopeptidase
CJF12_RS10580	COG1484	DNA-dependent DNA replication
CJF12_RS10585	COG4584	PFAM Integrase catalytic
CJF12_RS10685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CJF12_RS10700	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CJF12_RS10710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJF12_RS10710	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJF12_RS10715	COG1739	Uncharacterized protein family UPF0029
CJF12_RS10730	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJF12_RS10735	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJF12_RS10740	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJF12_RS10745	COG0649	NAD binding
CJF12_RS10750	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CJF12_RS10755	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CJF12_RS10765	COG1034	ATP synthesis coupled electron transport
CJF12_RS10770	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CJF12_RS10775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJF12_RS10780	COG0839	Belongs to the complex I subunit 6 family
CJF12_RS10790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CJF12_RS10795	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJF12_RS10800	COG1007	ATP synthesis coupled electron transport
CJF12_RS10830	COG3956	TIGRFAM MazG family protein
CJF12_RS10840	COG0242	peptide deformylase activity
CJF12_RS10845	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CJF12_RS10865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJF12_RS10885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CJF12_RS10890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CJF12_RS10895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJF12_RS10905	COG0564	pseudouridine synthase activity
CJF12_RS10915	COG1181	Belongs to the D-alanine--D-alanine ligase family
CJF12_RS10920	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CJF12_RS10940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CJF12_RS10945	COG1704	LemA family
CJF12_RS10975	COG0339	signal peptide processing
CJF12_RS10980	COG3012	SEC-C Motif Domain Protein
CJF12_RS10985	COG1047	Peptidyl-prolyl cis-trans
CJF12_RS10990	COG4628	conserved protein (DUF2132)
CJF12_RS10995	COG0420	3'-5' exonuclease activity
CJF12_RS11000	COG0419	ATPase involved in DNA repair
CJF12_RS11010	COG0419	ATPase involved in DNA repair
CJF12_RS11030	COG0823	Involved in the tonB-independent uptake of proteins
CJF12_RS11030	COG1506	peptidase
CJF12_RS11035	COG2353	YceI-like domain
CJF12_RS11040	COG3384	dioxygenase
CJF12_RS11045	COG1404	Belongs to the peptidase S8 family
CJF12_RS11055	COG2986	histidine ammonia-lyase
CJF12_RS11065	COG0322	excinuclease ABC activity
CJF12_RS11080	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJF12_RS11085	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CJF12_RS11150	COG1085	galactose-1-phosphate uridylyltransferase
CJF12_RS11155	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CJF12_RS11200	COG0509	glycine decarboxylation via glycine cleavage system
CJF12_RS11210	COG4584	PFAM Integrase catalytic
CJF12_RS11215	COG1484	DNA-dependent DNA replication
CJF12_RS11225	COG0632	four-way junction helicase activity
CJF12_RS11235	COG0280	phosphate acetyltransferase
CJF12_RS11235	COG0281	malic enzyme
CJF12_RS11275	COG2274	protein secretion by the type I secretion system
CJF12_RS11310	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CJF12_RS11320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CJF12_RS11330	COG1490	D-aminoacyl-tRNA deacylase activity
CJF12_RS11380	COG1408	metallophosphoesterase
CJF12_RS11415	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS11415	COG2030	dehydratase
CJF12_RS11430	COG0183	Belongs to the thiolase family
CJF12_RS11450	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJF12_RS11460	COG1024	Enoyl-CoA hydratase
CJF12_RS11465	COG2151	metal-sulfur cluster biosynthetic enzyme
CJF12_RS11475	COG3460	Phenylacetate-CoA oxygenase
CJF12_RS11480	COG3396	Phenylacetate-CoA oxygenase
CJF12_RS11485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CJF12_RS11490	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CJF12_RS11500	COG0542	response to heat
CJF12_RS11515	COG4585	Histidine kinase
CJF12_RS11520	COG2197	response regulator
CJF12_RS11530	COG0671	phosphoesterase, PA-phosphatase related
CJF12_RS11575	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS11595	COG3537	Alpha-1,2-mannosidase
CJF12_RS11605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CJF12_RS11615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CJF12_RS11630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJF12_RS11645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJF12_RS11655	COG1472	Belongs to the glycosyl hydrolase 3 family
CJF12_RS11660	COG0438	transferase activity, transferring glycosyl groups
CJF12_RS11695	COG2070	2-Nitropropane dioxygenase
CJF12_RS11740	COG1528	Iron-storage protein
CJF12_RS11755	COG1640	4-alpha-glucanotransferase
CJF12_RS11765	COG0215	cysteine-tRNA ligase activity
CJF12_RS11770	COG0302	gtp cyclohydrolase
CJF12_RS11840	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CJF12_RS11855	COG0646	methionine synthase
CJF12_RS11855	COG1410	methionine synthase
CJF12_RS11890	COG0714	Associated with various cellular activities
CJF12_RS11935	COG0217	transcriptional regulatory protein
CJF12_RS11945	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CJF12_RS11950	COG0488	(ABC) transporter
CJF12_RS11965	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CJF12_RS11965	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CJF12_RS11980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CJF12_RS12010	COG1834	amidinotransferase
CJF12_RS12020	COG0148	phosphopyruvate hydratase activity
CJF12_RS12035	COG0203	ribosomal protein L17
CJF12_RS12040	COG0202	RNA polymerase activity
CJF12_RS12045	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CJF12_RS12050	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CJF12_RS12055	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CJF12_RS12060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CJF12_RS12065	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CJF12_RS12075	COG0200	Binds to the 23S rRNA
CJF12_RS12080	COG1841	ribosomal large subunit assembly
CJF12_RS12095	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CJF12_RS12100	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CJF12_RS12105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJF12_RS12120	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CJF12_RS12125	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CJF12_RS12130	COG0255	Belongs to the universal ribosomal protein uL29 family
CJF12_RS12135	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CJF12_RS12140	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CJF12_RS12145	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CJF12_RS12150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CJF12_RS12155	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CJF12_RS12160	COG0089	rRNA binding
CJF12_RS12165	COG0088	Forms part of the polypeptide exit tunnel
CJF12_RS12170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CJF12_RS12175	COG1349	DNA-binding transcription factor activity
CJF12_RS12185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CJF12_RS12190	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CJF12_RS12235	COG4774	siderophore transport
CJF12_RS12240	COG0051	transcription antitermination factor activity, RNA binding
CJF12_RS12245	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CJF12_RS12250	COG0049	tRNA binding
CJF12_RS12255	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CJF12_RS12270	COG0783	Belongs to the Dps family
CJF12_RS12275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CJF12_RS12305	COG0745	RESPONSE REGULATOR receiver
CJF12_RS12315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJF12_RS12340	COG1054	Belongs to the UPF0176 family
CJF12_RS12355	COG0251	oxidation-reduction process
CJF12_RS12380	COG0268	Binds directly to 16S ribosomal RNA
CJF12_RS12395	COG4584	PFAM Integrase catalytic
CJF12_RS12400	COG1484	DNA-dependent DNA replication
CJF12_RS12415	COG2186	Transcriptional regulator
CJF12_RS12420	COG2223	nitrite transmembrane transporter activity
CJF12_RS12450	COG4206	TonB-dependent receptor
CJF12_RS12455	COG1858	cytochrome C peroxidase
CJF12_RS12480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CJF12_RS12485	COG1999	signal sequence binding
CJF12_RS12500	COG2217	Heavy metal translocating P-type atpase
CJF12_RS12515	COG3781	membrane
CJF12_RS12575	COG1629	transport
CJF12_RS12600	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CJF12_RS12605	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CJF12_RS12625	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CJF12_RS12640	COG1629	transport
CJF12_RS12650	COG4771	TonB-dependent receptor
CJF12_RS12665	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CJF12_RS12670	COG0195	Participates in both transcription termination and antitermination
CJF12_RS12675	COG0779	Required for maturation of 30S ribosomal subunits
CJF12_RS12725	COG3754	Rhamnan synthesis protein F
CJF12_RS12740	COG0463	Glycosyl transferase, family 2
CJF12_RS12750	COG1442	glycosyl transferase family 8
CJF12_RS12765	COG1216	Glycosyl transferase, family 2
CJF12_RS12785	COG0463	Glycosyl transferase, family 2
CJF12_RS12790	COG0438	transferase activity, transferring glycosyl groups
CJF12_RS12805	COG0110	maltose O-acetyltransferase activity
CJF12_RS12810	COG0288	reversible hydration of carbon dioxide
CJF12_RS12820	COG0659	secondary active sulfate transmembrane transporter activity
CJF12_RS12835	COG0193	aminoacyl-tRNA hydrolase activity
CJF12_RS12860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CJF12_RS12905	COG0305	Participates in initiation and elongation during chromosome replication
CJF12_RS12910	COG0328	RNA-DNA hybrid ribonuclease activity
CJF12_RS12925	COG0778	Nitroreductase
CJF12_RS12940	COG4772	TonB-dependent receptor
CJF12_RS12955	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CJF12_RS12960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CJF12_RS12985	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CJF12_RS12990	COG1611	Belongs to the LOG family
CJF12_RS13030	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CJF12_RS13050	COG1132	(ABC) transporter
CJF12_RS13070	COG0688	phosphatidylethanolamine metabolic process
CJF12_RS13085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJF12_RS13090	COG0799	negative regulation of ribosome biogenesis
CJF12_RS13105	COG0343	queuine tRNA-ribosyltransferase activity
CJF12_RS13115	COG0463	Glycosyl transferase, family 2
CJF12_RS13130	COG1770	oligopeptidase
CJF12_RS13175	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CJF12_RS13180	COG1082	Xylose isomerase domain protein TIM barrel
CJF12_RS13205	COG0363	glucosamine-6-phosphate deaminase activity
CJF12_RS13220	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CJF12_RS13240	COG2169	Transcriptional regulator
CJF12_RS13245	COG2207	Transcriptional regulator
CJF12_RS13250	COG1764	response to oxidative stress
CJF12_RS13255	COG1309	transcriptional regulator
CJF12_RS13260	COG0183	Belongs to the thiolase family
CJF12_RS13285	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJF12_RS13290	COG2733	membrane
CJF12_RS13295	COG0167	dihydroorotate dehydrogenase activity
CJF12_RS13300	COG0564	pseudouridine synthase activity
CJF12_RS13310	COG0423	glycine-tRNA ligase activity
CJF12_RS13330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJF12_RS13335	COG1876	peptidase activity
CJF12_RS13340	COG3621	Patatin-like phospholipase
CJF12_RS13380	COG4191	Histidine kinase
CJF12_RS13385	COG2204	response regulator
CJF12_RS13400	COG1136	(ABC) transporter
CJF12_RS13410	COG0577	efflux transmembrane transporter activity
CJF12_RS13430	COG0590	tRNA wobble adenosine to inosine editing
CJF12_RS13440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CJF12_RS13460	COG0791	NLP P60 protein
CJF12_RS13470	COG0772	Belongs to the SEDS family
CJF12_RS13475	COG0768	penicillin binding
CJF12_RS13500	COG0181	hydroxymethylbilane synthase activity
CJF12_RS13510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CJF12_RS13530	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CJF12_RS13535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CJF12_RS13550	COG1774	PSP1 C-terminal conserved region
CJF12_RS13560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJF12_RS13565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CJF12_RS13585	COG0437	4 iron, 4 sulfur cluster binding
CJF12_RS13620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CJF12_RS13630	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CJF12_RS13635	COG1368	sulfuric ester hydrolase activity
CJF12_RS13640	COG2321	neutral zinc metallopeptidase
CJF12_RS13655	COG0316	Belongs to the HesB IscA family
CJF12_RS13660	COG0719	Fe-S assembly protein
CJF12_RS13665	COG0396	ATPase activity
CJF12_RS13670	COG0719	Fe-S assembly protein
CJF12_RS13685	COG0758	DNA mediated transformation
CJF12_RS13715	COG2346	COG2346, Truncated hemoglobins
CJF12_RS13720	COG0387	Pfam Sodium calcium exchanger
CJF12_RS13745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CJF12_RS13750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJF12_RS13760	COG3591	Belongs to the peptidase S1B family
CJF12_RS13775	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CJF12_RS13785	COG0606	chelatase, subunit chli
CJF12_RS13795	COG1522	sequence-specific DNA binding
CJF12_RS13810	COG1595	DNA-templated transcription, initiation
CJF12_RS13830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJF12_RS13840	COG2151	metal-sulfur cluster biosynthetic enzyme
CJF12_RS13855	COG2195	Cleaves the N-terminal amino acid of tripeptides
CJF12_RS13900	COG3275	phosphorelay sensor kinase activity
CJF12_RS13905	COG3279	Response regulator of the LytR AlgR family
CJF12_RS13925	COG1484	DNA-dependent DNA replication
CJF12_RS13930	COG4584	PFAM Integrase catalytic
CJF12_RS13945	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CJF12_RS13955	COG2081	HI0933 family
CJF12_RS13975	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CJF12_RS13980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJF12_RS14000	COG3781	membrane
CJF12_RS14015	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CJF12_RS14025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CJF12_RS14035	COG2715	membrane protein required for spore maturation
CJF12_RS14055	COG0811	peptide transport
CJF12_RS14075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CJF12_RS14080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CJF12_RS14085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJF12_RS14110	COG0285	dihydrofolate synthase activity
CJF12_RS14125	COG0463	Glycosyl transferase, family 2
CJF12_RS14135	COG2166	iron-sulfur cluster assembly
CJF12_RS14150	COG0542	response to heat
CJF12_RS14160	COG0482	sulfurtransferase activity
CJF12_RS14165	COG3279	Response regulator of the LytR AlgR family
CJF12_RS14185	COG3275	phosphorelay sensor kinase activity
CJF12_RS14195	COG4771	TonB-dependent receptor
CJF12_RS14200	COG2032	superoxide dismutase activity
CJF12_RS14205	COG3264	Mechanosensitive ion channel
CJF12_RS14205	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CJF12_RS14210	COG0793	Belongs to the peptidase S41A family
CJF12_RS14215	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CJF12_RS14240	COG0516	GMP reductase activity
CJF12_RS14245	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS14255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CJF12_RS14265	COG1435	thymidine kinase activity
CJF12_RS14270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CJF12_RS14280	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CJF12_RS14285	COG0445	tRNA wobble uridine modification
CJF12_RS14295	COG0126	phosphoglycerate kinase activity
CJF12_RS14300	COG0698	ribose 5-phosphate isomerase
CJF12_RS14310	COG0557	exoribonuclease II activity
CJF12_RS14320	COG1619	proteins homologs of microcin C7 resistance protein MccF
CJF12_RS14330	COG0792	nuclease activity
CJF12_RS14335	COG4221	oxidoreductase activity
CJF12_RS14340	COG1214	PFAM Peptidase M22, glycoprotease
CJF12_RS14350	COG0424	maF-like protein
CJF12_RS14355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CJF12_RS14365	COG1595	DNA-templated transcription, initiation
CJF12_RS14395	COG0481	GTPase activity
CJF12_RS14440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CJF12_RS14445	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CJF12_RS14450	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CJF12_RS14500	COG3645	SOS response
CJF12_RS14505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CJF12_RS14515	COG0604	alcohol dehydrogenase
CJF12_RS14600	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CJF12_RS14605	COG0697	spore germination
CJF12_RS14650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJF12_RS14655	COG0579	oxidoreductase
CJF12_RS14675	COG0745	RESPONSE REGULATOR receiver
CJF12_RS14695	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CJF12_RS14730	COG1629	transport
CJF12_RS14735	COG3250	beta-galactosidase activity
CJF12_RS14750	COG1610	YqeY-like protein
CJF12_RS14755	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CJF12_RS14770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CJF12_RS14775	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJF12_RS14785	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CJF12_RS14790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJF12_RS14800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CJF12_RS14805	COG0768	penicillin binding
CJF12_RS14815	COG0275	rRNA processing
CJF12_RS14820	COG2001	Belongs to the MraZ family
CJF12_RS14830	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CJF12_RS14835	COG2153	protein acetylation
CJF12_RS14850	COG2356	endonuclease I
CJF12_RS14855	COG1940	carbohydrate kinase activity
CJF12_RS14880	COG4774	siderophore transport
CJF12_RS14885	COG0653	protein targeting
CJF12_RS14895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJF12_RS14930	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CJF12_RS14955	COG0628	permease
CJF12_RS14975	COG0556	nucleotide-excision repair
CJF12_RS14990	COG2133	pyrroloquinoline quinone binding
CJF12_RS15000	COG3033	Beta-eliminating lyase
CJF12_RS15025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CJF12_RS15030	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CJF12_RS15070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJF12_RS15075	COG3118	belongs to the thioredoxin family
CJF12_RS15085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJF12_RS15085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJF12_RS15095	COG0433	COG0433 Predicted ATPase
CJF12_RS15105	COG2176	DNA-directed DNA polymerase activity
CJF12_RS15115	COG0028	Belongs to the TPP enzyme family
CJF12_RS15125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJF12_RS15140	COG3829	transcription factor binding
CJF12_RS15170	COG0594	ribonuclease P activity
CJF12_RS15175	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CJF12_RS15210	COG0497	DNA recombination
CJF12_RS15225	COG2837	iron assimilation
CJF12_RS15250	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CJF12_RS15250	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CJF12_RS15260	COG1609	Transcriptional regulator
CJF12_RS15260	COG2207	Transcriptional regulator
CJF12_RS15270	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CJF12_RS15315	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CJF12_RS15325	COG1505	serine-type exopeptidase activity
CJF12_RS15340	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJF12_RS15340	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJF12_RS15365	COG1703	isobutyryl-CoA mutase activity
CJF12_RS15390	COG1127	ABC transporter
CJF12_RS15395	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CJF12_RS15405	COG0602	queuosine metabolic process
CJF12_RS15410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CJF12_RS15420	COG3420	alginic acid biosynthetic process
CJF12_RS15430	COG1960	acyl-CoA dehydrogenase activity
CJF12_RS15445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CJF12_RS15450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJF12_RS15455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CJF12_RS15460	COG0247	lactate metabolic process
CJF12_RS15460	COG2181	nitrate reductase activity
CJF12_RS15465	COG0247	lactate metabolic process
CJF12_RS15465	COG2181	nitrate reductase activity
CJF12_RS15475	COG0438	transferase activity, transferring glycosyl groups
CJF12_RS15495	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CJF12_RS15515	COG0348	domain, Protein
CJF12_RS15540	COG2217	Heavy metal translocating P-type atpase
CJF12_RS15550	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CJF12_RS15560	COG0564	pseudouridine synthase activity
CJF12_RS15580	COG0352	thiamine-phosphate diphosphorylase activity
CJF12_RS15585	COG2022	thiamine diphosphate biosynthetic process
CJF12_RS15610	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CJF12_RS15640	COG1607	acyl-coa hydrolase
CJF12_RS15650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJF12_RS15655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJF12_RS15675	COG4974	Belongs to the 'phage' integrase family
CJF12_RS15685	COG1024	Enoyl-CoA hydratase
CJF12_RS15700	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CJF12_RS15730	COG0745	RESPONSE REGULATOR receiver
CJF12_RS15740	COG5002	protein histidine kinase activity
CJF12_RS15745	COG0180	Tryptophanyl-tRNA synthetase
CJF12_RS15750	COG2949	membrane
CJF12_RS15755	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CJF12_RS15770	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CJF12_RS15775	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CJF12_RS15780	COG0739	heme binding
CJF12_RS15790	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CJF12_RS15805	COG2986	histidine ammonia-lyase
CJF12_RS15810	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS15815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJF12_RS15820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJF12_RS15845	COG1505	serine-type exopeptidase activity
CJF12_RS15910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJF12_RS15935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJF12_RS15940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJF12_RS15950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJF12_RS15965	COG1131	(ABC) transporter
CJF12_RS15990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJF12_RS16000	COG2409	Drug exporters of the RND superfamily
CJF12_RS16030	COG1216	Glycosyl transferase, family 2
CJF12_RS16030	COG1442	glycosyl transferase family 8
CJF12_RS16035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJF12_RS16160	COG0179	Fumarylacetoacetate (FAA) hydrolase
CJF12_RS16175	COG4206	TonB-dependent receptor
CJF12_RS16175	COG1629	transport
CJF12_RS16210	COG3511	phospholipase C
CJF12_RS16220	COG4771	TonB-dependent receptor
CJF12_RS16230	COG0300	oxidoreductase activity
CJF12_RS16235	COG1629	transport
CJF12_RS16240	COG0702	epimerase
CJF12_RS16255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CJF12_RS16270	COG0254	rRNA binding
CJF12_RS16305	COG0516	GMP reductase activity
CJF12_RS16305	COG0517	IMP dehydrogenase activity
CJF12_RS16310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CJF12_RS16310	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CJF12_RS16345	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CJF12_RS16380	COG0612	Peptidase, M16
CJF12_RS16385	COG1703	isobutyryl-CoA mutase activity
CJF12_RS16385	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJF12_RS16385	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJF12_RS16400	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CJF12_RS16405	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CJF12_RS16410	COG0052	Belongs to the universal ribosomal protein uS2 family
CJF12_RS16425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CJF12_RS16455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CJF12_RS16465	COG0825	malonyl-CoA metabolic process
CJF12_RS16470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJF12_RS16480	COG0463	Glycosyl transferase, family 2
CJF12_RS16510	COG0438	transferase activity, transferring glycosyl groups
CJF12_RS16525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJF12_RS16530	COG0439	Biotin carboxylase
CJF12_RS16535	COG0511	ligase activity, forming carbon-carbon bonds
CJF12_RS16540	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CJF12_RS16550	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CJF12_RS16555	COG0307	riboflavin synthase, alpha
CJF12_RS16565	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CJF12_RS16570	COG2884	Cell division ATP-binding protein ftsE
CJF12_RS16575	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CJF12_RS16580	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CJF12_RS16620	COG0037	tRNA processing
CJF12_RS16650	COG1519	Transferase
CJF12_RS16650	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CJF12_RS16670	COG0495	leucyl-tRNA aminoacylation
CJF12_RS16710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CJF12_RS16725	COG1132	(ABC) transporter
CJF12_RS16730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJF12_RS16740	COG1862	Preprotein translocase
CJF12_RS16745	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS16750	COG0668	transmembrane transport
CJF12_RS16755	COG3285	dna ligase
CJF12_RS16755	COG1793	dna ligase
CJF12_RS16765	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CJF12_RS16775	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CJF12_RS16780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CJF12_RS16805	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJF12_RS16815	COG0658	competence protein
CJF12_RS16815	COG2333	competence protein COMEC
CJF12_RS16825	COG1053	succinate dehydrogenase
CJF12_RS16830	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CJF12_RS16840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CJF12_RS16875	COG0237	dephospho-CoA kinase activity
CJF12_RS16880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJF12_RS16890	COG2255	four-way junction helicase activity
CJF12_RS16895	COG1228	amidohydrolase
CJF12_RS16900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CJF12_RS16905	COG0010	Belongs to the arginase family
CJF12_RS16910	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS16915	COG0469	pyruvate kinase activity
CJF12_RS16930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJF12_RS16935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJF12_RS16965	COG1595	DNA-templated transcription, initiation
CJF12_RS17010	COG4584	PFAM Integrase catalytic
CJF12_RS17015	COG1484	DNA-dependent DNA replication
CJF12_RS17030	COG1724	mRNA binding
CJF12_RS17075	COG4974	Belongs to the 'phage' integrase family
CJF12_RS17120	COG0745	RESPONSE REGULATOR receiver
CJF12_RS17145	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CJF12_RS17180	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CJF12_RS17185	COG0081	regulation of translation
CJF12_RS17190	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CJF12_RS17195	COG0222	ribosome binding
CJF12_RS17215	COG0085	RNA polymerase activity
CJF12_RS17220	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CJF12_RS17235	COG0456	acetyltransferase
CJF12_RS17250	COG1733	regulation of RNA biosynthetic process
CJF12_RS17255	COG2207	Transcriptional regulator
CJF12_RS17260	COG1064	alcohol dehydrogenase
CJF12_RS17275	COG2272	Belongs to the type-B carboxylesterase lipase family
CJF12_RS17285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJF12_RS17295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJF12_RS17305	COG1663	tetraacyldisaccharide 4'-kinase activity
CJF12_RS17360	COG0477	Major facilitator Superfamily
CJF12_RS17370	COG5002	protein histidine kinase activity
CJF12_RS17375	COG0745	RESPONSE REGULATOR receiver
CJF12_RS17385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJF12_RS17400	COG2318	DinB family
CJF12_RS17475	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CJF12_RS17480	COG1301	dicarboxylic acid transport
CJF12_RS17485	COG2851	Citrate transporter
CJF12_RS17500	COG4565	transcriptional regulatory protein
CJF12_RS17560	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CJF12_RS17575	COG0504	CTP synthase activity
CJF12_RS17580	COG0706	membrane insertase activity
CJF12_RS17585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CJF12_RS17590	COG4206	TonB-dependent receptor
CJF12_RS17590	COG1629	transport
CJF12_RS17600	COG4771	TonB-dependent receptor
CJF12_RS17610	COG4771	TonB-dependent receptor
CJF12_RS17620	COG0018	arginyl-trna synthetase
CJF12_RS17730	COG0326	Molecular chaperone. Has ATPase activity
CJF12_RS17735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CJF12_RS17745	COG2197	response regulator
CJF12_RS17755	COG0205	6-phosphofructokinase activity
CJF12_RS17780	COG2363	Small membrane protein
CJF12_RS17785	COG0038	chloride channel
CJF12_RS17805	COG0045	succinate-CoA ligase (ADP-forming) activity
CJF12_RS17810	COG0668	transmembrane transport
CJF12_RS17815	COG0450	alkyl hydroperoxide reductase
CJF12_RS17830	COG0673	inositol 2-dehydrogenase activity
CJF12_RS17835	COG0488	(ABC) transporter
CJF12_RS17840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CJF12_RS17855	COG0336	Belongs to the RNA methyltransferase TrmD family
CJF12_RS17865	COG1522	sequence-specific DNA binding
CJF12_RS17930	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CJF12_RS17930	COG0284	orotidine-5'-phosphate decarboxylase activity
CJF12_RS17950	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CJF12_RS18025	COG1484	DNA-dependent DNA replication
CJF12_RS18030	COG4584	PFAM Integrase catalytic
CJF12_RS18035	COG4584	PFAM Integrase catalytic
CJF12_RS18040	COG1484	DNA-dependent DNA replication
CJF12_RS18065	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CJF12_RS18070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CJF12_RS18075	COG0083	homoserine kinase activity
CJF12_RS18080	COG0460	homoserine dehydrogenase
CJF12_RS18080	COG0527	aspartate kinase activity
CJF12_RS18090	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CJF12_RS18095	COG0194	GDP metabolic process
CJF12_RS18100	COG1561	YicC-like family, N-terminal region
CJF12_RS18105	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CJF12_RS18135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJF12_RS18135	COG2207	Transcriptional regulator
CJF12_RS18155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJF12_RS18165	COG3227	Zinc metalloprotease (Elastase)
CJF12_RS18175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CJF12_RS18185	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CJF12_RS18195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CJF12_RS18205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJF12_RS18210	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJF12_RS18210	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJF12_RS18215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CJF12_RS18245	COG0616	signal peptide processing
CJF12_RS18250	COG2261	transglycosylase associated protein
CJF12_RS18255	COG0552	protein localization to endoplasmic reticulum
CJF12_RS18270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CJF12_RS18275	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CJF12_RS18285	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CJF12_RS18295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CJF12_RS18305	COG0436	Aminotransferase
CJF12_RS18330	COG1704	LemA family
CJF12_RS18340	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CJF12_RS18365	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CJF12_RS18385	COG1160	GTP binding
CJF12_RS18405	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CJF12_RS18415	COG1040	competence protein
CJF12_RS18425	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CJF12_RS18430	COG2224	Isocitrate lyase
CJF12_RS18435	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CJF12_RS18450	COG0720	synthase
CJF12_RS18455	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJF12_RS18505	COG0488	(ABC) transporter
CJF12_RS18525	COG0544	peptidyl-prolyl cis-trans isomerase activity
CJF12_RS18550	COG0589	response to stress
CJF12_RS18570	COG1183	phosphatidylcholine synthase activity
CJF12_RS18610	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJF12_RS18610	COG0022	dehydrogenase e1 component
CJF12_RS18615	COG3158	transport of potassium into the cell
CJF12_RS18630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJF12_RS18645	COG1678	Uncharacterized ACR, COG1678
CJF12_RS18650	COG0259	pyridoxamine-phosphate oxidase activity
CJF12_RS18665	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CJF12_RS18680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CJF12_RS18690	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS18720	COG0655	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS18725	COG2207	Transcriptional regulator
CJF12_RS18725	COG1917	Cupin 2, conserved barrel domain protein
CJF12_RS18745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CJF12_RS18750	COG0339	signal peptide processing
CJF12_RS18775	COG0228	four-way junction DNA binding
CJF12_RS18780	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CJF12_RS18800	COG0017	Asparaginyl-tRNA synthetase
CJF12_RS18810	COG0318	PFAM AMP-dependent synthetase and ligase
CJF12_RS18830	COG2326	polyphosphate kinase activity
CJF12_RS18840	COG0525	valine-tRNA ligase activity
CJF12_RS18850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJF12_RS18860	COG1418	mRNA catabolic process
CJF12_RS18920	COG1136	(ABC) transporter
CJF12_RS18925	COG0577	efflux transmembrane transporter activity
CJF12_RS18925	COG1136	(ABC) transporter
CJF12_RS18930	COG0577	efflux transmembrane transporter activity
CJF12_RS18930	COG1136	(ABC) transporter
CJF12_RS18940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJF12_RS18945	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CJF12_RS18950	COG2137	regulation of response to DNA damage stimulus
CJF12_RS18970	COG0489	protein tyrosine kinase activity
CJF12_RS18970	COG3206	protein involved in exopolysaccharide biosynthesis
CJF12_RS18975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJF12_RS18980	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CJF12_RS19010	COG1216	Glycosyl transferase, family 2
CJF12_RS19010	COG0463	Glycosyl transferase, family 2
CJF12_RS19015	COG0110	maltose O-acetyltransferase activity
CJF12_RS19035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJF12_RS19040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJF12_RS19045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJF12_RS19050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJF12_RS19070	COG1215	transferase activity, transferring glycosyl groups
CJF12_RS19105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJF12_RS19115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJF12_RS19135	COG0708	Exodeoxyribonuclease III
CJF12_RS19155	COG1078	dGTPase activity
CJF12_RS19160	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJF12_RS19165	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CJF12_RS19165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJF12_RS19175	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CJF12_RS19180	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJF12_RS19190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CJF12_RS19200	COG1668	transmembrane transport
CJF12_RS19205	COG4152	abc transporter atp-binding protein
CJF12_RS19215	COG0113	porphobilinogen synthase activity
CJF12_RS19235	COG1137	ATPase activity
CJF12_RS19245	COG1959	2 iron, 2 sulfur cluster binding
CJF12_RS19250	COG1017	nitric oxide dioxygenase activity
CJF12_RS19250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CJF12_RS19265	COG1132	(ABC) transporter
CJF12_RS19270	COG2378	regulation of single-species biofilm formation
CJF12_RS19300	COG2365	Tyrosine phosphatase family
CJF12_RS19310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJF12_RS19315	COG0010	Belongs to the arginase family
CJF12_RS19320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJF12_RS19350	COG1301	dicarboxylic acid transport
CJF12_RS19360	COG3537	Alpha-1,2-mannosidase
CJF12_RS19370	COG0489	protein tyrosine kinase activity
CJF12_RS19375	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CJF12_RS19385	COG2197	response regulator
CJF12_RS19400	COG0248	Ppx GppA phosphatase
CJF12_RS19405	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CJF12_RS19450	COG0366	Alpha amylase catalytic
CJF12_RS19480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CJF12_RS19485	COG1053	succinate dehydrogenase
CJF12_RS19495	COG0471	metal ion transport
CJF12_RS19505	COG4251	negative regulation of phosphorylation
CJF12_RS19525	COG2267	carboxylic ester hydrolase activity
CJF12_RS19540	COG1733	regulation of RNA biosynthetic process
CJF12_RS19550	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
CJF12_RS19555	COG2732	(Barnase) inhibitor
CJF12_RS19570	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CJF12_RS19580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJF12_RS19595	COG0626	cystathionine gamma-synthase activity
CJF12_RS19620	COG0009	L-threonylcarbamoyladenylate synthase
CJF12_RS19625	COG0617	tRNA 3'-terminal CCA addition
CJF12_RS19625	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CJF12_RS19625	COG0517	IMP dehydrogenase activity
CJF12_RS19690	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CJF12_RS19700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CJF12_RS19705	COG0402	S-adenosylhomocysteine deaminase activity
CJF12_RS19715	COG0402	S-adenosylhomocysteine deaminase activity
CJF12_RS19735	COG0745	RESPONSE REGULATOR receiver
CJF12_RS19740	COG5002	protein histidine kinase activity
CJF12_RS19785	COG3425	synthase
CJF12_RS19790	COG4771	TonB-dependent receptor
CJF12_RS19805	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS19820	COG0484	heat shock protein binding
CJF12_RS19845	COG3876	Protein conserved in bacteria
CJF12_RS19880	COG2909	trisaccharide binding
CJF12_RS19900	COG1484	DNA-dependent DNA replication
CJF12_RS19905	COG4584	PFAM Integrase catalytic