locus-tag	class	description
CJF12_RS00040	COG0358	DNA primase activity
CJF12_RS00045	COG4974	Belongs to the 'phage' integrase family
CJF12_RS00075	COG0358	DNA primase activity
CJF12_RS00080	COG4974	Belongs to the 'phage' integrase family
CJF12_RS00115	COG0358	DNA primase activity
CJF12_RS00135	COG4974	Belongs to the 'phage' integrase family
CJF12_RS00170	COG0358	DNA primase activity
CJF12_RS00175	COG4974	Belongs to the 'phage' integrase family
CJF12_RS00235	COG0527	aspartate kinase activity
CJF12_RS00240	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CJF12_RS00255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJF12_RS00270	COG0492	ferredoxin-NADP+ reductase activity
CJF12_RS00300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJF12_RS00320	COG0714	Associated with various cellular activities
CJF12_RS00340	COG2304	oxidoreductase activity
CJF12_RS00345	COG2304	oxidoreductase activity
CJF12_RS00360	COG2095	MarC family integral membrane protein
CJF12_RS00370	COG1169	isochorismate synthase
CJF12_RS00375	COG2050	protein possibly involved in aromatic compounds catabolism
CJF12_RS00405	COG1607	acyl-coa hydrolase
CJF12_RS00415	COG1193	negative regulation of DNA recombination
CJF12_RS00420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJF12_RS00440	COG0668	transmembrane transport
CJF12_RS00445	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CJF12_RS00450	COG2267	carboxylic ester hydrolase activity
CJF12_RS00480	COG1022	Amp-dependent synthetase and ligase
CJF12_RS00500	COG0346	lactoylglutathione lyase activity
CJF12_RS00510	COG0730	response to heat
CJF12_RS00520	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CJF12_RS00530	COG0475	glutathione-regulated potassium exporter activity
CJF12_RS00530	COG0589	response to stress
CJF12_RS00540	COG0697	spore germination
CJF12_RS00545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CJF12_RS00560	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CJF12_RS00590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CJF12_RS00625	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CJF12_RS00640	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS00650	COG1764	response to oxidative stress
CJF12_RS00660	COG1309	transcriptional regulator
CJF12_RS00675	COG2814	Major facilitator Superfamily
CJF12_RS00690	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS00705	COG0519	Catalyzes the synthesis of GMP from XMP
CJF12_RS00710	COG1733	regulation of RNA biosynthetic process
CJF12_RS00715	COG1733	regulation of RNA biosynthetic process
CJF12_RS00720	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS00740	COG0598	Magnesium transport protein CorA
CJF12_RS00745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJF12_RS00755	COG3118	belongs to the thioredoxin family
CJF12_RS00770	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS00780	COG0831	urea catabolic process
CJF12_RS00785	COG0832	Belongs to the urease beta subunit family
CJF12_RS00790	COG0804	urea catabolic process
CJF12_RS00800	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CJF12_RS00810	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CJF12_RS00815	COG0829	nickel cation binding
CJF12_RS00855	COG0006	proline dipeptidase activity
CJF12_RS00860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CJF12_RS00880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJF12_RS00885	COG2207	Transcriptional regulator
CJF12_RS00920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJF12_RS00970	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CJF12_RS01045	COG2197	response regulator
CJF12_RS01085	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CJF12_RS01105	COG2207	Transcriptional regulator
CJF12_RS01105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJF12_RS01125	COG4106	trans-aconitate 2-methyltransferase activity
CJF12_RS01130	COG1522	sequence-specific DNA binding
CJF12_RS01135	COG0477	Major facilitator Superfamily
CJF12_RS01145	COG1611	Belongs to the LOG family
CJF12_RS01155	COG2807	transmembrane transport
CJF12_RS01160	COG1472	Belongs to the glycosyl hydrolase 3 family
CJF12_RS01165	COG1464	Belongs to the NlpA lipoprotein family
CJF12_RS01170	COG2011	ABC-type metal ion transport system permease component
CJF12_RS01175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CJF12_RS01205	COG0738	Major facilitator superfamily
CJF12_RS01210	COG0246	Mannitol dehydrogenase
CJF12_RS01215	COG1609	Transcriptional regulator
CJF12_RS01230	COG4771	TonB-dependent receptor
CJF12_RS01235	COG0702	epimerase
CJF12_RS01240	COG0584	glycerophosphoryl diester phosphodiesterase
CJF12_RS01245	COG0584	glycerophosphoryl diester phosphodiesterase
CJF12_RS01250	COG1950	PFAM Membrane protein of
CJF12_RS01255	COG1506	peptidase
CJF12_RS01255	COG0823	Involved in the tonB-independent uptake of proteins
CJF12_RS01270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CJF12_RS01275	COG0673	inositol 2-dehydrogenase activity
CJF12_RS01290	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CJF12_RS01295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CJF12_RS01310	COG0142	geranyltranstransferase activity
CJF12_RS01320	COG0022	dehydrogenase e1 component
CJF12_RS01395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJF12_RS01420	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CJF12_RS01425	COG1131	(ABC) transporter
CJF12_RS01465	COG2267	carboxylic ester hydrolase activity
CJF12_RS01470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJF12_RS01475	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS01475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJF12_RS01475	COG4221	oxidoreductase activity
CJF12_RS01475	COG3321	synthase
CJF12_RS01480	COG0604	alcohol dehydrogenase
CJF12_RS01480	COG3321	synthase
CJF12_RS01540	COG4584	PFAM Integrase catalytic
CJF12_RS01545	COG1484	DNA-dependent DNA replication
CJF12_RS01550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CJF12_RS01585	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJF12_RS01605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJF12_RS01625	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CJF12_RS01640	COG4574	serine-type endopeptidase inhibitor activity
CJF12_RS01650	COG2274	protein secretion by the type I secretion system
CJF12_RS01670	COG1505	serine-type exopeptidase activity
CJF12_RS01675	COG1770	oligopeptidase
CJF12_RS01740	COG3781	membrane
CJF12_RS01745	COG0025	NhaP-type Na H and K H
CJF12_RS01775	COG1428	Deoxynucleoside kinase
CJF12_RS01780	COG1393	Belongs to the ArsC family
CJF12_RS01795	COG1629	transport
CJF12_RS01800	COG0702	epimerase
CJF12_RS01835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJF12_RS01870	COG0592	DNA-directed DNA polymerase activity
CJF12_RS01895	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJF12_RS01930	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CJF12_RS01950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CJF12_RS01970	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS01985	COG3059	membrane
CJF12_RS01990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJF12_RS01990	COG2207	Transcriptional regulator
CJF12_RS02015	COG0667	Aldo Keto reductase
CJF12_RS02035	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CJF12_RS02040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJF12_RS02115	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS02155	COG1191	sigma factor activity
CJF12_RS02170	COG0484	heat shock protein binding
CJF12_RS02185	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJF12_RS02185	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJF12_RS02220	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CJF12_RS02240	COG0531	amino acid
CJF12_RS02285	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CJF12_RS02290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CJF12_RS02295	COG0363	glucosamine-6-phosphate deaminase activity
CJF12_RS02305	COG1473	amidohydrolase
CJF12_RS02310	COG2706	6-phosphogluconolactonase activity
CJF12_RS02315	COG3119	arylsulfatase activity
CJF12_RS02320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CJF12_RS02325	COG3119	arylsulfatase activity
CJF12_RS02330	COG1335	isochorismatase
CJF12_RS02340	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS02345	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS02350	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS02365	COG2814	Major facilitator Superfamily
CJF12_RS02375	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CJF12_RS02400	COG2183	response to ionizing radiation
CJF12_RS02425	COG0693	protein deglycase activity
CJF12_RS02440	COG1649	PFAM Uncharacterised BCR, COG1649
CJF12_RS02450	COG1528	Iron-storage protein
CJF12_RS02455	COG0012	GTP binding
CJF12_RS02465	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS02475	COG0436	Aminotransferase
CJF12_RS02485	COG3279	Response regulator of the LytR AlgR family
CJF12_RS02490	COG2972	Histidine kinase
CJF12_RS02495	COG2205	protein histidine kinase activity
CJF12_RS02495	COG3292	Two component regulator propeller
CJF12_RS02495	COG0745	RESPONSE REGULATOR receiver
CJF12_RS02520	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS02525	COG1090	epimerase
CJF12_RS02545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJF12_RS02555	COG2890	protein-(glutamine-N5) methyltransferase activity
CJF12_RS02560	COG3022	response to hydroperoxide
CJF12_RS02565	COG0009	L-threonylcarbamoyladenylate synthase
CJF12_RS02615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CJF12_RS02630	COG3340	Belongs to the peptidase S51 family
CJF12_RS02640	COG3852	Histidine kinase
CJF12_RS02660	COG0805	protein transport
CJF12_RS02675	COG0517	IMP dehydrogenase activity
CJF12_RS02675	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CJF12_RS02680	COG0514	ATP-dependent DNA helicase (RecQ)
CJF12_RS02685	COG0438	transferase activity, transferring glycosyl groups
CJF12_RS02690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJF12_RS02705	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS02710	COG2996	Protein conserved in bacteria
CJF12_RS02725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJF12_RS02735	COG0484	heat shock protein binding
CJF12_RS02740	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CJF12_RS02755	COG0494	nUDIX hydrolase
CJF12_RS02765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CJF12_RS02770	COG1090	epimerase
CJF12_RS02790	COG1942	4-Oxalocrotonate Tautomerase
CJF12_RS02810	COG0629	single-stranded DNA binding
CJF12_RS02820	COG0124	histidyl-tRNA synthetase
CJF12_RS02825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CJF12_RS02830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CJF12_RS02840	COG1446	asparaginase
CJF12_RS02845	COG4242	Belongs to the peptidase S51 family
CJF12_RS02870	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CJF12_RS02890	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CJF12_RS02900	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CJF12_RS02905	COG0297	glycogen (starch) synthase activity
CJF12_RS02910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CJF12_RS02925	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJF12_RS02930	COG2967	ApaG domain
CJF12_RS02935	COG2176	DNA-directed DNA polymerase activity
CJF12_RS02940	COG0463	Glycosyl transferase, family 2
CJF12_RS02960	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS02985	COG0359	binds to the 23S rRNA
CJF12_RS02990	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CJF12_RS02995	COG0360	Binds together with S18 to 16S ribosomal RNA
CJF12_RS03010	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJF12_RS03020	COG1702	phosphate starvation-inducible protein PhoH
CJF12_RS03045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CJF12_RS03055	COG0356	it plays a direct role in the translocation of protons across the membrane
CJF12_RS03060	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJF12_RS03065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CJF12_RS03070	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJF12_RS03075	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CJF12_RS03080	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CJF12_RS03085	COG1253	flavin adenine dinucleotide binding
CJF12_RS03110	COG0572	uridine kinase
CJF12_RS03120	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJF12_RS03120	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJF12_RS03150	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS03160	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CJF12_RS03170	COG2211	Major facilitator Superfamily
CJF12_RS03185	COG0183	Belongs to the thiolase family
CJF12_RS03190	COG2270	Major facilitator Superfamily
CJF12_RS03230	COG0531	amino acid
CJF12_RS03265	COG2323	membrane
CJF12_RS03300	COG1575	Belongs to the MenA family. Type 1 subfamily
CJF12_RS03310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CJF12_RS03325	COG0463	Glycosyl transferase, family 2
CJF12_RS03345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CJF12_RS03360	COG3813	Protein conserved in bacteria
CJF12_RS03365	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CJF12_RS03375	COG0386	Belongs to the glutathione peroxidase family
CJF12_RS03405	COG0196	riboflavin kinase activity
CJF12_RS03410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CJF12_RS03415	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CJF12_RS03435	COG0156	8-amino-7-oxononanoate synthase activity
CJF12_RS03470	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CJF12_RS03495	COG2132	Multicopper oxidase
CJF12_RS03515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CJF12_RS03555	COG1321	iron dependent repressor
CJF12_RS03600	COG0640	Transcriptional regulator
CJF12_RS03605	COG2194	sulfuric ester hydrolase activity
CJF12_RS03610	COG0671	phosphoesterase, PA-phosphatase related
CJF12_RS03640	COG1252	NADH dehydrogenase
CJF12_RS03650	COG3275	phosphorelay sensor kinase activity
CJF12_RS03665	COG1484	DNA-dependent DNA replication
CJF12_RS03670	COG4584	PFAM Integrase catalytic
CJF12_RS03695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJF12_RS03725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CJF12_RS03730	COG1648	precorrin-2 dehydrogenase activity
CJF12_RS03730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CJF12_RS03740	COG1045	serine acetyltransferase
CJF12_RS03750	COG0175	sulfate reduction
CJF12_RS03755	COG0175	sulfate reduction
CJF12_RS03760	COG1959	2 iron, 2 sulfur cluster binding
CJF12_RS03785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJF12_RS03800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJF12_RS03810	COG0006	proline dipeptidase activity
CJF12_RS03815	COG1506	peptidase
CJF12_RS03815	COG0823	Involved in the tonB-independent uptake of proteins
CJF12_RS03815	COG4946	Tricorn protease homolog
CJF12_RS03820	COG2094	Belongs to the DNA glycosylase MPG family
CJF12_RS03825	COG3663	DNA glycosylase
CJF12_RS03830	COG2076	Multidrug Resistance protein
CJF12_RS03855	COG3279	Response regulator of the LytR AlgR family
CJF12_RS03860	COG3275	phosphorelay sensor kinase activity
CJF12_RS03865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJF12_RS03875	COG2814	Major facilitator Superfamily
CJF12_RS03900	COG1349	DNA-binding transcription factor activity
CJF12_RS03905	COG2223	nitrite transmembrane transporter activity
CJF12_RS03910	COG0346	lactoylglutathione lyase activity
CJF12_RS03930	COG1285	pathogenesis
CJF12_RS03935	COG0671	phosphoesterase, PA-phosphatase related
CJF12_RS03945	COG4771	TonB-dependent receptor
CJF12_RS03960	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS03975	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CJF12_RS03980	COG0667	Aldo Keto reductase
CJF12_RS03985	COG1546	Belongs to the CinA family
CJF12_RS03985	COG1058	Belongs to the CinA family
CJF12_RS03990	COG3685	Protein conserved in bacteria
CJF12_RS04020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJF12_RS04025	COG3279	Response regulator of the LytR AlgR family
CJF12_RS04045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJF12_RS04050	COG0596	Alpha beta hydrolase
CJF12_RS04055	COG0183	Belongs to the thiolase family
CJF12_RS04100	COG3275	phosphorelay sensor kinase activity
CJF12_RS04135	COG1285	pathogenesis
CJF12_RS04140	COG5002	protein histidine kinase activity
CJF12_RS04145	COG0745	RESPONSE REGULATOR receiver
CJF12_RS04165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJF12_RS04170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CJF12_RS04175	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CJF12_RS04180	COG0156	8-amino-7-oxononanoate synthase activity
CJF12_RS04190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJF12_RS04205	COG0076	glutamate decarboxylase activity
CJF12_RS04215	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CJF12_RS04225	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CJF12_RS04230	COG1733	regulation of RNA biosynthetic process
CJF12_RS04235	COG2084	Dehydrogenase
CJF12_RS04240	COG2084	Dehydrogenase
CJF12_RS04245	COG2814	Major facilitator Superfamily
CJF12_RS04255	COG0667	Aldo Keto reductase
CJF12_RS04260	COG2084	Dehydrogenase
CJF12_RS04270	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CJF12_RS04275	COG1609	Transcriptional regulator
CJF12_RS04280	COG2271	Major facilitator Superfamily
CJF12_RS04285	COG1904	glucuronate isomerase
CJF12_RS04290	COG1312	Catalyzes the dehydration of D-mannonate
CJF12_RS04295	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS04310	COG3250	beta-galactosidase activity
CJF12_RS04325	COG1629	transport
CJF12_RS04330	COG0702	epimerase
CJF12_RS04335	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CJF12_RS04340	COG4677	pectinesterase activity
CJF12_RS04345	COG5492	domain, Protein
CJF12_RS04350	COG3250	beta-galactosidase activity
CJF12_RS04360	COG0300	oxidoreductase activity
CJF12_RS04390	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS04395	COG1793	dna ligase
CJF12_RS04395	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CJF12_RS04400	COG1793	dna ligase
CJF12_RS04430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJF12_RS04455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJF12_RS04470	COG0025	NhaP-type Na H and K H
CJF12_RS04585	COG3871	stress protein (general stress protein 26)
CJF12_RS04615	COG0671	phosphoesterase, PA-phosphatase related
CJF12_RS04640	COG5002	protein histidine kinase activity
CJF12_RS04645	COG0745	RESPONSE REGULATOR receiver
CJF12_RS04650	COG1546	Belongs to the CinA family
CJF12_RS04650	COG1058	Belongs to the CinA family
CJF12_RS04655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJF12_RS04660	COG0697	spore germination
CJF12_RS04665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJF12_RS04685	COG2318	DinB family
CJF12_RS04690	COG0513	Belongs to the DEAD box helicase family
CJF12_RS04695	COG1335	isochorismatase
CJF12_RS04700	COG1187	pseudouridine synthase activity
CJF12_RS04705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CJF12_RS04735	COG0584	glycerophosphoryl diester phosphodiesterase
CJF12_RS04740	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CJF12_RS04760	COG2356	endonuclease I
CJF12_RS04765	COG1960	acyl-CoA dehydrogenase activity
CJF12_RS04795	COG0473	3-isopropylmalate dehydrogenase activity
CJF12_RS04800	COG0066	3-isopropylmalate dehydratase activity
CJF12_RS04805	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CJF12_RS04810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJF12_RS04830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CJF12_RS04835	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CJF12_RS04855	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CJF12_RS04860	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CJF12_RS04865	COG2234	aminopeptidase activity
CJF12_RS04870	COG2234	aminopeptidase activity
CJF12_RS04915	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CJF12_RS04915	COG0140	phosphoribosyl-ATP diphosphatase activity
CJF12_RS04920	COG0107	imidazoleglycerol-phosphate synthase activity
CJF12_RS04925	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CJF12_RS04935	COG0131	Imidazoleglycerol-phosphate dehydratase
CJF12_RS04940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CJF12_RS04945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CJF12_RS04950	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CJF12_RS04960	COG0438	transferase activity, transferring glycosyl groups
CJF12_RS04970	COG0463	Glycosyl transferase, family 2
CJF12_RS04980	COG2171	N-acyltransferase activity
CJF12_RS05010	COG0791	NLP P60 protein
CJF12_RS05040	COG1484	DNA-dependent DNA replication
CJF12_RS05045	COG4584	PFAM Integrase catalytic
CJF12_RS05100	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS05125	COG1333	cytochrome c biogenesis protein
CJF12_RS05125	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CJF12_RS05130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CJF12_RS05160	COG1674	ftsk spoiiie
CJF12_RS05175	COG0233	cytoplasmic translational termination
CJF12_RS05180	COG0528	UMP kinase activity
CJF12_RS05210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJF12_RS05220	COG2949	membrane
CJF12_RS05225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CJF12_RS05230	COG3118	belongs to the thioredoxin family
CJF12_RS05245	COG1120	ATPase activity
CJF12_RS05255	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJF12_RS05255	COG1024	Enoyl-CoA hydratase
CJF12_RS05265	COG0183	Belongs to the thiolase family
CJF12_RS05270	COG1960	acyl-CoA dehydrogenase activity
CJF12_RS05275	COG3422	double-strand break repair
CJF12_RS05295	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CJF12_RS05350	COG1088	dTDP-glucose 4,6-dehydratase activity
CJF12_RS05360	COG1349	DNA-binding transcription factor activity
CJF12_RS05370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CJF12_RS05375	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CJF12_RS05385	COG0028	Belongs to the TPP enzyme family
CJF12_RS05390	COG0129	dihydroxy-acid dehydratase activity
CJF12_RS05405	COG2234	aminopeptidase activity
CJF12_RS05415	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CJF12_RS05425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CJF12_RS05445	COG2003	Belongs to the UPF0758 family
CJF12_RS05450	COG1136	(ABC) transporter
CJF12_RS05480	COG0724	RNA recognition motif
CJF12_RS05485	COG1607	acyl-coa hydrolase
CJF12_RS05495	COG2217	Heavy metal translocating P-type atpase
CJF12_RS05505	COG0726	polysaccharide deacetylase
CJF12_RS05515	COG2204	response regulator
CJF12_RS05520	COG0534	Mate efflux family protein
CJF12_RS05535	COG1506	peptidase
CJF12_RS05545	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CJF12_RS05565	COG2076	Multidrug Resistance protein
CJF12_RS05570	COG2226	methyltransferase
CJF12_RS05590	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CJF12_RS05620	COG0813	purine-nucleoside phosphorylase activity
CJF12_RS05630	COG0519	Catalyzes the synthesis of GMP from XMP
CJF12_RS05640	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CJF12_RS05650	COG1472	Belongs to the glycosyl hydrolase 3 family
CJF12_RS05665	COG4771	TonB-dependent receptor
CJF12_RS05680	COG1960	acyl-CoA dehydrogenase activity
CJF12_RS05715	COG0357	Ribosomal RNA small subunit methyltransferase G
CJF12_RS05720	COG2234	aminopeptidase activity
CJF12_RS05725	COG0436	Aminotransferase
CJF12_RS05730	COG0612	Peptidase, M16
CJF12_RS05735	COG0450	alkyl hydroperoxide reductase
CJF12_RS05740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJF12_RS05790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CJF12_RS05795	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CJF12_RS05800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJF12_RS05840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CJF12_RS05850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CJF12_RS05855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJF12_RS05855	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CJF12_RS05870	COG1363	Peptidase, m42
CJF12_RS05875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CJF12_RS05890	COG0105	UTP biosynthetic process
CJF12_RS05895	COG2814	Major facilitator Superfamily
CJF12_RS05905	COG1162	GTPase activity
CJF12_RS05910	COG1605	Chorismate mutase
CJF12_RS05910	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CJF12_RS05920	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CJF12_RS05930	COG0156	8-amino-7-oxononanoate synthase activity
CJF12_RS05975	COG0025	NhaP-type Na H and K H
CJF12_RS05980	COG2814	Major facilitator Superfamily
CJF12_RS05990	COG1785	Belongs to the alkaline phosphatase family
CJF12_RS06010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CJF12_RS06015	COG1174	glycine betaine transport
CJF12_RS06020	COG1125	glycine betaine transport
CJF12_RS06020	COG0517	IMP dehydrogenase activity
CJF12_RS06025	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CJF12_RS06075	COG3781	membrane
CJF12_RS06115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJF12_RS06120	COG1733	regulation of RNA biosynthetic process
CJF12_RS06125	COG1902	pentaerythritol trinitrate reductase activity
CJF12_RS06160	COG1917	Cupin 2, conserved barrel domain protein
CJF12_RS06160	COG2207	Transcriptional regulator
CJF12_RS06170	COG0303	'Molybdopterin
CJF12_RS06175	COG0315	cyclic pyranopterin monophosphate synthase activity
CJF12_RS06180	COG0746	molybdenum cofactor guanylyltransferase activity
CJF12_RS06185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CJF12_RS06195	COG3781	membrane
CJF12_RS06200	COG2223	nitrite transmembrane transporter activity
CJF12_RS06220	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CJF12_RS06225	COG0314	molybdopterin synthase activity
CJF12_RS06245	COG4221	oxidoreductase activity
CJF12_RS06255	COG4584	PFAM Integrase catalytic
CJF12_RS06260	COG1484	DNA-dependent DNA replication
CJF12_RS06305	COG2205	protein histidine kinase activity
CJF12_RS06305	COG0784	Response regulator, receiver
CJF12_RS06315	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CJF12_RS06320	COG3437	response regulator, receiver
CJF12_RS06330	COG5002	protein histidine kinase activity
CJF12_RS06335	COG2318	DinB family
CJF12_RS06350	COG0431	NADPH-dependent FMN reductase
CJF12_RS06355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CJF12_RS06365	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJF12_RS06425	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CJF12_RS06455	COG4771	TonB-dependent receptor
CJF12_RS06485	COG1733	regulation of RNA biosynthetic process
CJF12_RS06495	COG0667	Aldo Keto reductase
CJF12_RS06535	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CJF12_RS06550	COG1077	Cell shape determining protein MreB Mrl
CJF12_RS06555	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CJF12_RS06570	COG0492	ferredoxin-NADP+ reductase activity
CJF12_RS06585	COG1011	Hydrolase
CJF12_RS06615	COG2169	Transcriptional regulator
CJF12_RS06615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJF12_RS06655	COG0540	Belongs to the ATCase OTCase family
CJF12_RS06660	COG1522	sequence-specific DNA binding
CJF12_RS06665	COG0165	Argininosuccinate lyase
CJF12_RS06670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJF12_RS06675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CJF12_RS06685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJF12_RS06690	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CJF12_RS06695	COG0137	argininosuccinate synthase activity
CJF12_RS06735	COG0745	RESPONSE REGULATOR receiver
CJF12_RS06745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJF12_RS06755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CJF12_RS06760	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CJF12_RS06765	COG1295	ribonuclease BN
CJF12_RS06775	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CJF12_RS06785	COG0671	phosphoesterase, PA-phosphatase related
CJF12_RS06790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJF12_RS06805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJF12_RS06805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJF12_RS06810	COG2133	pyrroloquinoline quinone binding
CJF12_RS06820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJF12_RS06835	COG0531	amino acid
CJF12_RS06850	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CJF12_RS06855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CJF12_RS06870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJF12_RS06905	COG1733	regulation of RNA biosynthetic process
CJF12_RS06910	COG1979	alcohol dehydrogenase
CJF12_RS06925	COG0513	Belongs to the DEAD box helicase family
CJF12_RS06935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJF12_RS06935	COG3153	acetyltransferase
CJF12_RS06965	COG0519	Catalyzes the synthesis of GMP from XMP
CJF12_RS06965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CJF12_RS06970	COG0151	Belongs to the GarS family
CJF12_RS06980	COG2267	carboxylic ester hydrolase activity
CJF12_RS06985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CJF12_RS06990	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CJF12_RS07000	COG1741	Belongs to the pirin family
CJF12_RS07015	COG0366	Alpha amylase catalytic
CJF12_RS07020	COG1082	Xylose isomerase domain protein TIM barrel
CJF12_RS07030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CJF12_RS07035	COG1629	transport
CJF12_RS07035	COG4206	TonB-dependent receptor
CJF12_RS07040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJF12_RS07040	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJF12_RS07100	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CJF12_RS07105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJF12_RS07110	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CJF12_RS07120	COG0077	Prephenate dehydratase
CJF12_RS07140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CJF12_RS07145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CJF12_RS07150	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CJF12_RS07155	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CJF12_RS07155	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CJF12_RS07160	COG1970	mechanosensitive ion channel activity
CJF12_RS07165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJF12_RS07175	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CJF12_RS07185	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CJF12_RS07205	COG1607	acyl-coa hydrolase
CJF12_RS07215	COG0038	chloride channel
CJF12_RS07225	COG2855	membrane
CJF12_RS07235	COG0477	Major facilitator Superfamily
CJF12_RS07240	COG1418	mRNA catabolic process
CJF12_RS07260	COG2226	methyltransferase
CJF12_RS07270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJF12_RS07275	COG1408	metallophosphoesterase
CJF12_RS07280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CJF12_RS07290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJF12_RS07305	COG0405	Gamma-glutamyltransferase
CJF12_RS07310	COG1301	dicarboxylic acid transport
CJF12_RS07340	COG0187	DNA topoisomerase II activity
CJF12_RS07345	COG1271	oxidase subunit
CJF12_RS07360	COG0067	glutamate synthase
CJF12_RS07360	COG0069	glutamate synthase activity
CJF12_RS07360	COG0070	glutamate synthase
CJF12_RS07365	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CJF12_RS07370	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CJF12_RS07375	COG4654	Cytochrome c, class I
CJF12_RS07390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CJF12_RS07395	COG0512	Glutamine amidotransferase of anthranilate synthase
CJF12_RS07395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJF12_RS07400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJF12_RS07410	COG0134	indole-3-glycerol-phosphate synthase activity
CJF12_RS07415	COG0135	phosphoribosylanthranilate isomerase activity
CJF12_RS07430	COG0133	tryptophan synthase activity
CJF12_RS07435	COG0159	tryptophan synthase activity
CJF12_RS07440	COG0321	lipoyl(octanoyl) transferase activity
CJF12_RS07475	COG0778	Nitroreductase
CJF12_RS07480	COG1846	Transcriptional regulator
CJF12_RS07485	COG0242	peptide deformylase activity
CJF12_RS07500	COG3720	iron ion transport
CJF12_RS07515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJF12_RS07560	COG1959	2 iron, 2 sulfur cluster binding
CJF12_RS07595	COG1981	membrane
CJF12_RS07605	COG0156	8-amino-7-oxononanoate synthase activity
CJF12_RS07620	COG2027	D-alanyl-D-alanine carboxypeptidase
CJF12_RS07625	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CJF12_RS07635	COG0679	Auxin Efflux Carrier
CJF12_RS07645	COG3250	beta-galactosidase activity
CJF12_RS07655	COG3142	Participates in the control of copper homeostasis
CJF12_RS07660	COG1446	asparaginase
CJF12_RS07665	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CJF12_RS07685	COG1132	(ABC) transporter
CJF12_RS07690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CJF12_RS07705	COG2259	Doxx family
CJF12_RS07715	COG0335	large ribosomal subunit rRNA binding
CJF12_RS07720	COG2207	Transcriptional regulator
CJF12_RS07725	COG2814	Major facilitator Superfamily
CJF12_RS07745	COG2183	response to ionizing radiation
CJF12_RS07745	COG0539	negative regulation of cytoplasmic translation
CJF12_RS07750	COG0513	Belongs to the DEAD box helicase family
CJF12_RS07760	COG0348	domain, Protein
CJF12_RS07785	COG1187	pseudouridine synthase activity
CJF12_RS07790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CJF12_RS07795	COG1968	undecaprenyl-diphosphatase activity
CJF12_RS07805	COG2177	Part of the ABC transporter FtsEX involved in
CJF12_RS07810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CJF12_RS07840	COG1234	tRNA 3'-trailer cleavage
CJF12_RS07845	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CJF12_RS07900	COG1960	acyl-CoA dehydrogenase activity
CJF12_RS07905	COG1022	Amp-dependent synthetase and ligase
CJF12_RS07915	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CJF12_RS07920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJF12_RS07940	COG0587	DNA-directed DNA polymerase activity
CJF12_RS07945	COG0022	dehydrogenase e1 component
CJF12_RS07950	COG3781	membrane
CJF12_RS07955	COG1522	sequence-specific DNA binding
CJF12_RS07960	COG0626	cystathionine gamma-synthase activity
CJF12_RS07985	COG0116	Belongs to the methyltransferase superfamily
CJF12_RS08000	COG4771	TonB-dependent receptor
CJF12_RS08005	COG0702	epimerase
CJF12_RS08020	COG0442	prolyl-tRNA aminoacylation
CJF12_RS08030	COG1914	H( )-stimulated, divalent metal cation uptake system
CJF12_RS08035	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CJF12_RS08040	COG0484	heat shock protein binding
CJF12_RS08050	COG2354	Protein conserved in bacteria
CJF12_RS08065	COG0586	Pfam SNARE associated Golgi protein
CJF12_RS08070	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CJF12_RS08075	COG2072	flavoprotein involved in K transport
CJF12_RS08080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJF12_RS08085	COG1131	(ABC) transporter
CJF12_RS08115	COG1595	DNA-templated transcription, initiation
CJF12_RS08120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CJF12_RS08145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CJF12_RS08165	COG0149	triose-phosphate isomerase activity
CJF12_RS08180	COG0358	DNA primase activity
CJF12_RS08185	COG0802	atpase or kinase
CJF12_RS08215	COG0475	glutathione-regulated potassium exporter activity
CJF12_RS08225	COG0287	Prephenate dehydrogenase
CJF12_RS08230	COG1760	l-serine dehydratase
CJF12_RS08255	COG0837	glucose binding
CJF12_RS08280	COG1185	polyribonucleotide nucleotidyltransferase activity
CJF12_RS08290	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CJF12_RS08300	COG2239	Acts as a magnesium transporter
CJF12_RS08305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJF12_RS08320	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CJF12_RS08320	COG0321	lipoyl(octanoyl) transferase activity
CJF12_RS08330	COG4771	TonB-dependent receptor
CJF12_RS08340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJF12_RS08345	COG0477	Major facilitator Superfamily
CJF12_RS08350	COG1309	transcriptional regulator
CJF12_RS08375	COG2079	MmgE PrpD family protein
CJF12_RS08390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJF12_RS08405	COG0387	Pfam Sodium calcium exchanger
CJF12_RS08420	COG0513	Belongs to the DEAD box helicase family
CJF12_RS08430	COG1278	Cold shock
CJF12_RS08440	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS08455	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CJF12_RS08470	COG2267	carboxylic ester hydrolase activity
CJF12_RS08480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJF12_RS08520	COG3590	peptidase
CJF12_RS08525	COG3590	peptidase
CJF12_RS08530	COG1215	transferase activity, transferring glycosyl groups
CJF12_RS08535	COG1546	Belongs to the CinA family
CJF12_RS08535	COG1058	Belongs to the CinA family
CJF12_RS08545	COG3279	Response regulator of the LytR AlgR family
CJF12_RS08550	COG3275	phosphorelay sensor kinase activity
CJF12_RS08570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJF12_RS08570	COG0723	plastoquinol--plastocyanin reductase activity
CJF12_RS08590	COG2814	Major facilitator Superfamily
CJF12_RS08595	COG1917	Cupin 2, conserved barrel domain protein
CJF12_RS08595	COG2207	Transcriptional regulator
CJF12_RS08605	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CJF12_RS08615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CJF12_RS08630	COG0793	Belongs to the peptidase S41A family
CJF12_RS08630	COG3409	Peptidoglycan-binding domain 1 protein
CJF12_RS08730	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CJF12_RS08735	COG0633	Ferredoxin
CJF12_RS08750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJF12_RS08755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJF12_RS08760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJF12_RS08800	COG1770	oligopeptidase
CJF12_RS08830	COG1104	cysteine desulfurase activity
CJF12_RS08850	COG0277	FAD linked oxidase domain protein
CJF12_RS08855	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CJF12_RS08880	COG0681	Belongs to the peptidase S26 family
CJF12_RS08885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CJF12_RS08895	COG1475	DNA binding
CJF12_RS08900	COG1192	Involved in chromosome partitioning
CJF12_RS08910	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CJF12_RS08920	COG0488	(ABC) transporter
CJF12_RS08925	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CJF12_RS08930	COG0563	adenylate kinase activity
CJF12_RS08935	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CJF12_RS08945	COG0513	Belongs to the DEAD box helicase family
CJF12_RS08950	COG0084	hydrolase, TatD family'
CJF12_RS08970	COG0306	phosphate transporter
CJF12_RS08990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJF12_RS08995	COG1136	(ABC) transporter
CJF12_RS09000	COG0577	efflux transmembrane transporter activity
CJF12_RS09000	COG1136	(ABC) transporter
CJF12_RS09030	COG1027	Aspartate ammonia-lyase
CJF12_RS09035	COG3023	N-Acetylmuramoyl-L-alanine amidase
CJF12_RS09055	COG2827	Endonuclease containing a URI domain
CJF12_RS09065	COG1733	regulation of RNA biosynthetic process
CJF12_RS09085	COG3239	Fatty acid desaturase
CJF12_RS09100	COG2264	protein methyltransferase activity
CJF12_RS09105	COG0300	oxidoreductase activity
CJF12_RS09120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CJF12_RS09135	COG4717	serine-type aminopeptidase activity
CJF12_RS09140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJF12_RS09175	COG0702	epimerase
CJF12_RS09185	COG4771	TonB-dependent receptor
CJF12_RS09190	COG0612	Peptidase, M16
CJF12_RS09200	COG2204	response regulator
CJF12_RS09210	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CJF12_RS09220	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CJF12_RS09235	COG2205	protein histidine kinase activity
CJF12_RS09260	COG1335	isochorismatase
CJF12_RS09295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJF12_RS09295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJF12_RS09315	COG3501	Rhs element vgr protein
CJF12_RS09345	COG3501	Rhs element vgr protein
CJF12_RS09360	COG0542	response to heat
CJF12_RS09390	COG2197	response regulator
CJF12_RS09395	COG0776	regulation of translation
CJF12_RS09400	COG1530	ribonuclease E activity
CJF12_RS09430	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CJF12_RS09455	COG2070	2-Nitropropane dioxygenase
CJF12_RS09480	COG0656	L-ascorbic acid biosynthetic process
CJF12_RS09490	COG0456	acetyltransferase
CJF12_RS09500	COG0583	DNA-binding transcription factor activity
CJF12_RS09510	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS09525	COG0667	Aldo Keto reductase
CJF12_RS09540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CJF12_RS09565	COG4771	TonB-dependent receptor
CJF12_RS09570	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CJF12_RS09575	COG0427	acetyl-CoA hydrolase
CJF12_RS09585	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CJF12_RS09630	COG1966	Carbon starvation protein
CJF12_RS09635	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CJF12_RS09640	COG0352	thiamine-phosphate diphosphorylase activity
CJF12_RS09645	COG0351	phosphomethylpyrimidine kinase
CJF12_RS09645	COG0352	thiamine-phosphate diphosphorylase activity
CJF12_RS09650	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CJF12_RS09655	COG4771	TonB-dependent receptor
CJF12_RS09665	COG0612	Peptidase, M16
CJF12_RS09670	COG0612	Peptidase, M16
CJF12_RS09685	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CJF12_RS09700	COG2195	Cleaves the N-terminal amino acid of tripeptides
CJF12_RS09710	COG0492	ferredoxin-NADP+ reductase activity
CJF12_RS09720	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CJF12_RS09730	COG3842	ATPase activity
CJF12_RS09735	COG2824	Alkylphosphonate utilization operon protein PhnA
CJF12_RS09740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CJF12_RS09740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJF12_RS09750	COG0367	asparagine synthase
CJF12_RS09760	COG0477	Major facilitator Superfamily
CJF12_RS09775	COG1741	Belongs to the pirin family
CJF12_RS09780	COG0431	NADPH-dependent FMN reductase
CJF12_RS09800	COG2388	GCN5-related N-acetyl-transferase
CJF12_RS09805	COG4145	pantothenate transmembrane transporter activity
CJF12_RS09810	COG3959	Transketolase, thiamine diphosphate binding domain
CJF12_RS09815	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CJF12_RS09825	COG1309	transcriptional regulator
CJF12_RS09840	COG1522	sequence-specific DNA binding
CJF12_RS09850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CJF12_RS09860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CJF12_RS09880	COG0252	asparaginase activity
CJF12_RS09900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJF12_RS09910	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CJF12_RS09925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJF12_RS09990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CJF12_RS09995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CJF12_RS10005	COG0297	glycogen (starch) synthase activity
CJF12_RS10010	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CJF12_RS10030	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CJF12_RS10035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CJF12_RS10045	COG0069	glutamate synthase activity
CJF12_RS10050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJF12_RS10085	COG1506	peptidase
CJF12_RS10085	COG0823	Involved in the tonB-independent uptake of proteins
CJF12_RS10095	COG3104	oligopeptide transport
CJF12_RS10100	COG3104	oligopeptide transport
CJF12_RS10110	COG4232	protein-disulfide reductase activity
CJF12_RS10115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CJF12_RS10135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJF12_RS10140	COG0737	Belongs to the 5'-nucleotidase family
CJF12_RS10145	COG0737	Belongs to the 5'-nucleotidase family
CJF12_RS10230	COG0579	oxidoreductase
CJF12_RS10240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJF12_RS10245	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CJF12_RS10250	COG0739	heme binding
CJF12_RS10260	COG2910	NAD(P)H-binding
CJF12_RS10300	COG3853	Toxic anion resistance protein (TelA)
CJF12_RS10315	COG0659	secondary active sulfate transmembrane transporter activity
CJF12_RS10380	COG0714	Associated with various cellular activities
CJF12_RS10395	COG0813	purine-nucleoside phosphorylase activity
CJF12_RS10410	COG1505	serine-type exopeptidase activity
CJF12_RS10450	COG1073	alpha beta
CJF12_RS10475	COG0024	Methionine aminopeptidase
CJF12_RS10490	COG1484	DNA-dependent DNA replication
CJF12_RS10495	COG4584	PFAM Integrase catalytic
CJF12_RS10595	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CJF12_RS10610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CJF12_RS10620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJF12_RS10620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJF12_RS10625	COG1739	Uncharacterized protein family UPF0029
CJF12_RS10640	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJF12_RS10645	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJF12_RS10650	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJF12_RS10655	COG0649	NAD binding
CJF12_RS10660	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CJF12_RS10665	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CJF12_RS10675	COG1034	ATP synthesis coupled electron transport
CJF12_RS10680	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CJF12_RS10685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJF12_RS10690	COG0839	Belongs to the complex I subunit 6 family
CJF12_RS10700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CJF12_RS10705	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJF12_RS10710	COG1007	ATP synthesis coupled electron transport
CJF12_RS10740	COG3956	TIGRFAM MazG family protein
CJF12_RS10750	COG0242	peptide deformylase activity
CJF12_RS10755	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CJF12_RS10775	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJF12_RS10795	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CJF12_RS10800	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CJF12_RS10805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJF12_RS10815	COG0564	pseudouridine synthase activity
CJF12_RS10825	COG1181	Belongs to the D-alanine--D-alanine ligase family
CJF12_RS10830	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CJF12_RS10850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CJF12_RS10855	COG1704	LemA family
CJF12_RS10885	COG0339	signal peptide processing
CJF12_RS10890	COG3012	SEC-C Motif Domain Protein
CJF12_RS10895	COG1047	Peptidyl-prolyl cis-trans
CJF12_RS10900	COG4628	conserved protein (DUF2132)
CJF12_RS10905	COG0420	3'-5' exonuclease activity
CJF12_RS10910	COG0419	ATPase involved in DNA repair
CJF12_RS10930	COG0823	Involved in the tonB-independent uptake of proteins
CJF12_RS10930	COG1506	peptidase
CJF12_RS10935	COG2353	YceI-like domain
CJF12_RS10940	COG3384	dioxygenase
CJF12_RS10945	COG1404	Belongs to the peptidase S8 family
CJF12_RS10955	COG2986	histidine ammonia-lyase
CJF12_RS10965	COG0322	excinuclease ABC activity
CJF12_RS10980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJF12_RS10985	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CJF12_RS11015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CJF12_RS11050	COG1085	galactose-1-phosphate uridylyltransferase
CJF12_RS11055	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CJF12_RS11100	COG0509	glycine decarboxylation via glycine cleavage system
CJF12_RS11110	COG4584	PFAM Integrase catalytic
CJF12_RS11115	COG1484	DNA-dependent DNA replication
CJF12_RS11125	COG0632	four-way junction helicase activity
CJF12_RS11135	COG0281	malic enzyme
CJF12_RS11135	COG0280	phosphate acetyltransferase
CJF12_RS11175	COG2274	protein secretion by the type I secretion system
CJF12_RS11210	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CJF12_RS11220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CJF12_RS11230	COG1490	D-aminoacyl-tRNA deacylase activity
CJF12_RS11280	COG1408	metallophosphoesterase
CJF12_RS11315	COG2030	dehydratase
CJF12_RS11315	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS11330	COG0183	Belongs to the thiolase family
CJF12_RS11350	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJF12_RS11360	COG1024	Enoyl-CoA hydratase
CJF12_RS11365	COG2151	metal-sulfur cluster biosynthetic enzyme
CJF12_RS11375	COG3460	Phenylacetate-CoA oxygenase
CJF12_RS11380	COG3396	Phenylacetate-CoA oxygenase
CJF12_RS11385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CJF12_RS11390	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CJF12_RS11400	COG0542	response to heat
CJF12_RS11420	COG4585	Histidine kinase
CJF12_RS11425	COG2197	response regulator
CJF12_RS11435	COG0671	phosphoesterase, PA-phosphatase related
CJF12_RS11480	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS11500	COG3537	Alpha-1,2-mannosidase
CJF12_RS11510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CJF12_RS11520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CJF12_RS11535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJF12_RS11550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJF12_RS11560	COG1472	Belongs to the glycosyl hydrolase 3 family
CJF12_RS11565	COG0438	transferase activity, transferring glycosyl groups
CJF12_RS11600	COG2070	2-Nitropropane dioxygenase
CJF12_RS11630	COG1074	ATP-dependent DNA helicase activity
CJF12_RS11645	COG1528	Iron-storage protein
CJF12_RS11660	COG1640	4-alpha-glucanotransferase
CJF12_RS11670	COG0215	cysteine-tRNA ligase activity
CJF12_RS11675	COG0302	gtp cyclohydrolase
CJF12_RS11740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CJF12_RS11755	COG1410	methionine synthase
CJF12_RS11755	COG0646	methionine synthase
CJF12_RS11790	COG0714	Associated with various cellular activities
CJF12_RS11835	COG0217	transcriptional regulatory protein
CJF12_RS11845	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CJF12_RS11850	COG0488	(ABC) transporter
CJF12_RS11865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CJF12_RS11865	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CJF12_RS11880	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CJF12_RS11910	COG1834	amidinotransferase
CJF12_RS11920	COG0148	phosphopyruvate hydratase activity
CJF12_RS11935	COG0203	ribosomal protein L17
CJF12_RS11940	COG0202	RNA polymerase activity
CJF12_RS11945	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CJF12_RS11950	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CJF12_RS11955	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CJF12_RS11960	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CJF12_RS11965	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CJF12_RS11975	COG0200	Binds to the 23S rRNA
CJF12_RS11980	COG1841	ribosomal large subunit assembly
CJF12_RS11985	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CJF12_RS11990	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CJF12_RS11995	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CJF12_RS12000	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CJF12_RS12005	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJF12_RS12010	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CJF12_RS12020	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CJF12_RS12025	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CJF12_RS12030	COG0255	Belongs to the universal ribosomal protein uL29 family
CJF12_RS12035	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CJF12_RS12040	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CJF12_RS12045	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CJF12_RS12050	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CJF12_RS12055	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CJF12_RS12060	COG0089	rRNA binding
CJF12_RS12065	COG0088	Forms part of the polypeptide exit tunnel
CJF12_RS12070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CJF12_RS12075	COG1349	DNA-binding transcription factor activity
CJF12_RS12085	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CJF12_RS12090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CJF12_RS12130	COG4771	TonB-dependent receptor
CJF12_RS12135	COG4774	siderophore transport
CJF12_RS12140	COG0051	transcription antitermination factor activity, RNA binding
CJF12_RS12145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CJF12_RS12150	COG0049	tRNA binding
CJF12_RS12155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CJF12_RS12170	COG0783	Belongs to the Dps family
CJF12_RS12175	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CJF12_RS12205	COG0745	RESPONSE REGULATOR receiver
CJF12_RS12215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJF12_RS12240	COG1054	Belongs to the UPF0176 family
CJF12_RS12245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJF12_RS12255	COG0251	oxidation-reduction process
CJF12_RS12280	COG0268	Binds directly to 16S ribosomal RNA
CJF12_RS12295	COG4584	PFAM Integrase catalytic
CJF12_RS12300	COG1484	DNA-dependent DNA replication
CJF12_RS12315	COG2186	Transcriptional regulator
CJF12_RS12320	COG2223	nitrite transmembrane transporter activity
CJF12_RS12350	COG4206	TonB-dependent receptor
CJF12_RS12355	COG1858	cytochrome C peroxidase
CJF12_RS12380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CJF12_RS12385	COG1999	signal sequence binding
CJF12_RS12400	COG2217	Heavy metal translocating P-type atpase
CJF12_RS12415	COG3781	membrane
CJF12_RS12475	COG1629	transport
CJF12_RS12500	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CJF12_RS12505	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CJF12_RS12525	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CJF12_RS12540	COG1629	transport
CJF12_RS12550	COG4771	TonB-dependent receptor
CJF12_RS12560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CJF12_RS12565	COG0195	Participates in both transcription termination and antitermination
CJF12_RS12570	COG0779	Required for maturation of 30S ribosomal subunits
CJF12_RS12575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CJF12_RS12620	COG3754	Rhamnan synthesis protein F
CJF12_RS12635	COG0463	Glycosyl transferase, family 2
CJF12_RS12645	COG1442	glycosyl transferase family 8
CJF12_RS12660	COG1216	Glycosyl transferase, family 2
CJF12_RS12680	COG0463	Glycosyl transferase, family 2
CJF12_RS12685	COG0438	transferase activity, transferring glycosyl groups
CJF12_RS12700	COG0110	maltose O-acetyltransferase activity
CJF12_RS12705	COG0288	reversible hydration of carbon dioxide
CJF12_RS12715	COG0659	secondary active sulfate transmembrane transporter activity
CJF12_RS12730	COG0193	aminoacyl-tRNA hydrolase activity
CJF12_RS12755	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CJF12_RS12800	COG0305	Participates in initiation and elongation during chromosome replication
CJF12_RS12805	COG0328	RNA-DNA hybrid ribonuclease activity
CJF12_RS12820	COG0778	Nitroreductase
CJF12_RS12825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CJF12_RS12835	COG4772	TonB-dependent receptor
CJF12_RS12850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CJF12_RS12855	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CJF12_RS12880	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CJF12_RS12885	COG1611	Belongs to the LOG family
CJF12_RS12925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CJF12_RS12945	COG1132	(ABC) transporter
CJF12_RS12965	COG0688	phosphatidylethanolamine metabolic process
CJF12_RS12980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJF12_RS12985	COG0799	negative regulation of ribosome biogenesis
CJF12_RS13000	COG0343	queuine tRNA-ribosyltransferase activity
CJF12_RS13010	COG0463	Glycosyl transferase, family 2
CJF12_RS13025	COG1770	oligopeptidase
CJF12_RS13070	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CJF12_RS13075	COG1082	Xylose isomerase domain protein TIM barrel
CJF12_RS13100	COG0363	glucosamine-6-phosphate deaminase activity
CJF12_RS13115	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CJF12_RS13135	COG2169	Transcriptional regulator
CJF12_RS13140	COG2207	Transcriptional regulator
CJF12_RS13145	COG1764	response to oxidative stress
CJF12_RS13150	COG1309	transcriptional regulator
CJF12_RS13155	COG0183	Belongs to the thiolase family
CJF12_RS13180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJF12_RS13185	COG2733	membrane
CJF12_RS13190	COG0167	dihydroorotate dehydrogenase activity
CJF12_RS13195	COG0564	pseudouridine synthase activity
CJF12_RS13205	COG0423	glycine-tRNA ligase activity
CJF12_RS13225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJF12_RS13230	COG1876	peptidase activity
CJF12_RS13235	COG3621	Patatin-like phospholipase
CJF12_RS13265	COG4191	Histidine kinase
CJF12_RS13270	COG2204	response regulator
CJF12_RS13285	COG1136	(ABC) transporter
CJF12_RS13295	COG0577	efflux transmembrane transporter activity
CJF12_RS13315	COG0590	tRNA wobble adenosine to inosine editing
CJF12_RS13325	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CJF12_RS13345	COG0791	NLP P60 protein
CJF12_RS13355	COG0772	Belongs to the SEDS family
CJF12_RS13360	COG0768	penicillin binding
CJF12_RS13380	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CJF12_RS13385	COG0181	hydroxymethylbilane synthase activity
CJF12_RS13395	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CJF12_RS13415	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CJF12_RS13420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CJF12_RS13435	COG1774	PSP1 C-terminal conserved region
CJF12_RS13445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJF12_RS13450	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CJF12_RS13470	COG0437	4 iron, 4 sulfur cluster binding
CJF12_RS13505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CJF12_RS13515	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CJF12_RS13520	COG1368	sulfuric ester hydrolase activity
CJF12_RS13525	COG2321	neutral zinc metallopeptidase
CJF12_RS13540	COG0316	Belongs to the HesB IscA family
CJF12_RS13545	COG0719	Fe-S assembly protein
CJF12_RS13550	COG0396	ATPase activity
CJF12_RS13555	COG0719	Fe-S assembly protein
CJF12_RS13570	COG0758	DNA mediated transformation
CJF12_RS13600	COG2346	COG2346, Truncated hemoglobins
CJF12_RS13605	COG0387	Pfam Sodium calcium exchanger
CJF12_RS13630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CJF12_RS13635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJF12_RS13645	COG3591	Belongs to the peptidase S1B family
CJF12_RS13660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CJF12_RS13670	COG0606	chelatase, subunit chli
CJF12_RS13680	COG1522	sequence-specific DNA binding
CJF12_RS13695	COG1595	DNA-templated transcription, initiation
CJF12_RS13715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJF12_RS13725	COG2151	metal-sulfur cluster biosynthetic enzyme
CJF12_RS13740	COG2195	Cleaves the N-terminal amino acid of tripeptides
CJF12_RS13785	COG3275	phosphorelay sensor kinase activity
CJF12_RS13810	COG1484	DNA-dependent DNA replication
CJF12_RS13815	COG4584	PFAM Integrase catalytic
CJF12_RS13830	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CJF12_RS13840	COG2081	HI0933 family
CJF12_RS13860	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CJF12_RS13865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJF12_RS13885	COG3781	membrane
CJF12_RS13900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CJF12_RS13910	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CJF12_RS13920	COG2715	membrane protein required for spore maturation
CJF12_RS13940	COG0811	peptide transport
CJF12_RS13960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CJF12_RS13965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CJF12_RS13970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJF12_RS13995	COG0285	dihydrofolate synthase activity
CJF12_RS14010	COG0463	Glycosyl transferase, family 2
CJF12_RS14020	COG2166	iron-sulfur cluster assembly
CJF12_RS14035	COG0542	response to heat
CJF12_RS14045	COG0482	sulfurtransferase activity
CJF12_RS14050	COG3279	Response regulator of the LytR AlgR family
CJF12_RS14070	COG3275	phosphorelay sensor kinase activity
CJF12_RS14080	COG4771	TonB-dependent receptor
CJF12_RS14085	COG2032	superoxide dismutase activity
CJF12_RS14090	COG3264	Mechanosensitive ion channel
CJF12_RS14090	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CJF12_RS14095	COG0793	Belongs to the peptidase S41A family
CJF12_RS14100	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CJF12_RS14125	COG0516	GMP reductase activity
CJF12_RS14130	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS14140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CJF12_RS14150	COG1435	thymidine kinase activity
CJF12_RS14155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CJF12_RS14165	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CJF12_RS14170	COG0445	tRNA wobble uridine modification
CJF12_RS14180	COG0126	phosphoglycerate kinase activity
CJF12_RS14185	COG0698	ribose 5-phosphate isomerase
CJF12_RS14195	COG0557	exoribonuclease II activity
CJF12_RS14205	COG1619	proteins homologs of microcin C7 resistance protein MccF
CJF12_RS14215	COG0792	nuclease activity
CJF12_RS14220	COG4221	oxidoreductase activity
CJF12_RS14225	COG1214	PFAM Peptidase M22, glycoprotease
CJF12_RS14235	COG0424	maF-like protein
CJF12_RS14240	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CJF12_RS14250	COG1595	DNA-templated transcription, initiation
CJF12_RS14280	COG0481	GTPase activity
CJF12_RS14325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CJF12_RS14335	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CJF12_RS14385	COG3645	SOS response
CJF12_RS14390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CJF12_RS14400	COG0604	alcohol dehydrogenase
CJF12_RS14485	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CJF12_RS14490	COG0697	spore germination
CJF12_RS14535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJF12_RS14540	COG0579	oxidoreductase
CJF12_RS14560	COG0745	RESPONSE REGULATOR receiver
CJF12_RS14580	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CJF12_RS14615	COG1629	transport
CJF12_RS14620	COG3250	beta-galactosidase activity
CJF12_RS14635	COG1610	YqeY-like protein
CJF12_RS14640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CJF12_RS14655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CJF12_RS14660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJF12_RS14670	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CJF12_RS14675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJF12_RS14685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CJF12_RS14690	COG0768	penicillin binding
CJF12_RS14700	COG0275	rRNA processing
CJF12_RS14705	COG2001	Belongs to the MraZ family
CJF12_RS14715	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CJF12_RS14720	COG2153	protein acetylation
CJF12_RS14730	COG2356	endonuclease I
CJF12_RS14735	COG1940	carbohydrate kinase activity
CJF12_RS14760	COG4774	siderophore transport
CJF12_RS14765	COG0653	protein targeting
CJF12_RS14775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJF12_RS14810	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CJF12_RS14835	COG0628	permease
CJF12_RS14855	COG0556	nucleotide-excision repair
CJF12_RS14870	COG2133	pyrroloquinoline quinone binding
CJF12_RS14880	COG3033	Beta-eliminating lyase
CJF12_RS14905	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CJF12_RS14910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CJF12_RS14950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJF12_RS14955	COG3118	belongs to the thioredoxin family
CJF12_RS14965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJF12_RS14965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJF12_RS14975	COG0433	COG0433 Predicted ATPase
CJF12_RS14985	COG2176	DNA-directed DNA polymerase activity
CJF12_RS14995	COG0028	Belongs to the TPP enzyme family
CJF12_RS15005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJF12_RS15020	COG3829	transcription factor binding
CJF12_RS15045	COG0594	ribonuclease P activity
CJF12_RS15050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CJF12_RS15085	COG0497	DNA recombination
CJF12_RS15100	COG2837	iron assimilation
CJF12_RS15125	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CJF12_RS15125	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CJF12_RS15135	COG2207	Transcriptional regulator
CJF12_RS15135	COG1609	Transcriptional regulator
CJF12_RS15145	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CJF12_RS15190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CJF12_RS15200	COG1505	serine-type exopeptidase activity
CJF12_RS15215	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJF12_RS15215	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJF12_RS15240	COG1703	isobutyryl-CoA mutase activity
CJF12_RS15265	COG1127	ABC transporter
CJF12_RS15270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CJF12_RS15275	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJF12_RS15280	COG0602	queuosine metabolic process
CJF12_RS15285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CJF12_RS15295	COG3420	alginic acid biosynthetic process
CJF12_RS15305	COG1960	acyl-CoA dehydrogenase activity
CJF12_RS15320	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CJF12_RS15325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJF12_RS15330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CJF12_RS15335	COG2181	nitrate reductase activity
CJF12_RS15335	COG0247	lactate metabolic process
CJF12_RS15340	COG0247	lactate metabolic process
CJF12_RS15340	COG2181	nitrate reductase activity
CJF12_RS15350	COG0438	transferase activity, transferring glycosyl groups
CJF12_RS15370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CJF12_RS15390	COG0348	domain, Protein
CJF12_RS15415	COG2217	Heavy metal translocating P-type atpase
CJF12_RS15425	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CJF12_RS15435	COG0564	pseudouridine synthase activity
CJF12_RS15455	COG0352	thiamine-phosphate diphosphorylase activity
CJF12_RS15460	COG2022	thiamine diphosphate biosynthetic process
CJF12_RS15485	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CJF12_RS15515	COG1607	acyl-coa hydrolase
CJF12_RS15525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJF12_RS15530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJF12_RS15550	COG4974	Belongs to the 'phage' integrase family
CJF12_RS15560	COG1024	Enoyl-CoA hydratase
CJF12_RS15575	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CJF12_RS15605	COG0745	RESPONSE REGULATOR receiver
CJF12_RS15610	COG5002	protein histidine kinase activity
CJF12_RS15615	COG0180	Tryptophanyl-tRNA synthetase
CJF12_RS15620	COG2949	membrane
CJF12_RS15625	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CJF12_RS15640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CJF12_RS15645	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CJF12_RS15650	COG0739	heme binding
CJF12_RS15660	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CJF12_RS15675	COG2986	histidine ammonia-lyase
CJF12_RS15680	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS15685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJF12_RS15690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJF12_RS15715	COG1505	serine-type exopeptidase activity
CJF12_RS15780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJF12_RS15805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJF12_RS15810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJF12_RS15820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJF12_RS15835	COG1131	(ABC) transporter
CJF12_RS15860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJF12_RS15870	COG2409	Drug exporters of the RND superfamily
CJF12_RS15900	COG1216	Glycosyl transferase, family 2
CJF12_RS15900	COG1442	glycosyl transferase family 8
CJF12_RS15905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJF12_RS16030	COG0179	Fumarylacetoacetate (FAA) hydrolase
CJF12_RS16045	COG4206	TonB-dependent receptor
CJF12_RS16045	COG1629	transport
CJF12_RS16080	COG3511	phospholipase C
CJF12_RS16090	COG4771	TonB-dependent receptor
CJF12_RS16100	COG0300	oxidoreductase activity
CJF12_RS16105	COG1629	transport
CJF12_RS16110	COG0702	epimerase
CJF12_RS16125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CJF12_RS16140	COG0254	rRNA binding
CJF12_RS16175	COG0516	GMP reductase activity
CJF12_RS16175	COG0517	IMP dehydrogenase activity
CJF12_RS16180	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CJF12_RS16180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CJF12_RS16215	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CJF12_RS16250	COG0612	Peptidase, M16
CJF12_RS16255	COG1703	isobutyryl-CoA mutase activity
CJF12_RS16255	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJF12_RS16255	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJF12_RS16270	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CJF12_RS16275	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CJF12_RS16280	COG0052	Belongs to the universal ribosomal protein uS2 family
CJF12_RS16295	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CJF12_RS16325	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CJF12_RS16335	COG0825	malonyl-CoA metabolic process
CJF12_RS16340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJF12_RS16350	COG0463	Glycosyl transferase, family 2
CJF12_RS16380	COG0438	transferase activity, transferring glycosyl groups
CJF12_RS16395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJF12_RS16400	COG0439	Biotin carboxylase
CJF12_RS16405	COG0511	ligase activity, forming carbon-carbon bonds
CJF12_RS16410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CJF12_RS16420	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CJF12_RS16425	COG0307	riboflavin synthase, alpha
CJF12_RS16435	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CJF12_RS16440	COG2884	Cell division ATP-binding protein ftsE
CJF12_RS16445	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CJF12_RS16450	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CJF12_RS16490	COG0037	tRNA processing
CJF12_RS16520	COG1519	Transferase
CJF12_RS16520	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CJF12_RS16540	COG0495	leucyl-tRNA aminoacylation
CJF12_RS16580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CJF12_RS16595	COG1132	(ABC) transporter
CJF12_RS16600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJF12_RS16610	COG1862	Preprotein translocase
CJF12_RS16615	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS16620	COG0668	transmembrane transport
CJF12_RS16625	COG1793	dna ligase
CJF12_RS16625	COG3285	dna ligase
CJF12_RS16635	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CJF12_RS16645	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CJF12_RS16650	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CJF12_RS16675	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJF12_RS16685	COG0658	competence protein
CJF12_RS16685	COG2333	competence protein COMEC
CJF12_RS16695	COG1053	succinate dehydrogenase
CJF12_RS16700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CJF12_RS16710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CJF12_RS16745	COG0237	dephospho-CoA kinase activity
CJF12_RS16750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJF12_RS16760	COG2255	four-way junction helicase activity
CJF12_RS16765	COG1228	amidohydrolase
CJF12_RS16770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CJF12_RS16775	COG0010	Belongs to the arginase family
CJF12_RS16780	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS16785	COG0469	pyruvate kinase activity
CJF12_RS16795	COG0571	ribonuclease III activity
CJF12_RS16800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJF12_RS16805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJF12_RS16835	COG1595	DNA-templated transcription, initiation
CJF12_RS16880	COG4584	PFAM Integrase catalytic
CJF12_RS16885	COG1484	DNA-dependent DNA replication
CJF12_RS16900	COG1724	mRNA binding
CJF12_RS16940	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CJF12_RS16945	COG4974	Belongs to the 'phage' integrase family
CJF12_RS16990	COG0745	RESPONSE REGULATOR receiver
CJF12_RS17015	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CJF12_RS17050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CJF12_RS17055	COG0081	regulation of translation
CJF12_RS17060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CJF12_RS17065	COG0222	ribosome binding
CJF12_RS17085	COG0085	RNA polymerase activity
CJF12_RS17090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CJF12_RS17105	COG0456	acetyltransferase
CJF12_RS17120	COG1733	regulation of RNA biosynthetic process
CJF12_RS17125	COG2207	Transcriptional regulator
CJF12_RS17130	COG1064	alcohol dehydrogenase
CJF12_RS17145	COG2272	Belongs to the type-B carboxylesterase lipase family
CJF12_RS17155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJF12_RS17165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJF12_RS17175	COG1663	tetraacyldisaccharide 4'-kinase activity
CJF12_RS17180	COG0101	tRNA pseudouridine synthase activity
CJF12_RS17190	COG1132	(ABC) transporter
CJF12_RS17230	COG0477	Major facilitator Superfamily
CJF12_RS17240	COG5002	protein histidine kinase activity
CJF12_RS17245	COG0745	RESPONSE REGULATOR receiver
CJF12_RS17255	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJF12_RS17270	COG2318	DinB family
CJF12_RS17345	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CJF12_RS17350	COG1301	dicarboxylic acid transport
CJF12_RS17355	COG2851	Citrate transporter
CJF12_RS17370	COG4565	transcriptional regulatory protein
CJF12_RS17430	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CJF12_RS17445	COG0504	CTP synthase activity
CJF12_RS17450	COG0706	membrane insertase activity
CJF12_RS17455	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CJF12_RS17460	COG1629	transport
CJF12_RS17460	COG4206	TonB-dependent receptor
CJF12_RS17470	COG4771	TonB-dependent receptor
CJF12_RS17480	COG4771	TonB-dependent receptor
CJF12_RS17490	COG0018	arginyl-trna synthetase
CJF12_RS17525	COG1113	amino acid transport
CJF12_RS17595	COG0326	Molecular chaperone. Has ATPase activity
CJF12_RS17600	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CJF12_RS17610	COG2197	response regulator
CJF12_RS17620	COG0205	6-phosphofructokinase activity
CJF12_RS17645	COG2363	Small membrane protein
CJF12_RS17650	COG0038	chloride channel
CJF12_RS17665	COG1132	(ABC) transporter
CJF12_RS17670	COG0045	succinate-CoA ligase (ADP-forming) activity
CJF12_RS17675	COG0668	transmembrane transport
CJF12_RS17680	COG0450	alkyl hydroperoxide reductase
CJF12_RS17695	COG0673	inositol 2-dehydrogenase activity
CJF12_RS17700	COG0488	(ABC) transporter
CJF12_RS17705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CJF12_RS17715	COG1252	NADH dehydrogenase
CJF12_RS17720	COG0336	Belongs to the RNA methyltransferase TrmD family
CJF12_RS17730	COG1522	sequence-specific DNA binding
CJF12_RS17795	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CJF12_RS17795	COG0284	orotidine-5'-phosphate decarboxylase activity
CJF12_RS17815	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CJF12_RS17890	COG1484	DNA-dependent DNA replication
CJF12_RS17895	COG4584	PFAM Integrase catalytic
CJF12_RS17900	COG4584	PFAM Integrase catalytic
CJF12_RS17905	COG1484	DNA-dependent DNA replication
CJF12_RS17930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CJF12_RS17935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CJF12_RS17940	COG0083	homoserine kinase activity
CJF12_RS17945	COG0527	aspartate kinase activity
CJF12_RS17945	COG0460	homoserine dehydrogenase
CJF12_RS17960	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CJF12_RS17965	COG0194	GDP metabolic process
CJF12_RS17970	COG1561	YicC-like family, N-terminal region
CJF12_RS17975	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CJF12_RS18005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJF12_RS18005	COG2207	Transcriptional regulator
CJF12_RS18025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJF12_RS18035	COG3227	Zinc metalloprotease (Elastase)
CJF12_RS18045	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CJF12_RS18055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CJF12_RS18065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CJF12_RS18075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJF12_RS18080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJF12_RS18080	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJF12_RS18085	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CJF12_RS18115	COG0616	signal peptide processing
CJF12_RS18120	COG2261	transglycosylase associated protein
CJF12_RS18125	COG0552	protein localization to endoplasmic reticulum
CJF12_RS18140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CJF12_RS18145	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CJF12_RS18155	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CJF12_RS18165	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CJF12_RS18175	COG0436	Aminotransferase
CJF12_RS18200	COG1704	LemA family
CJF12_RS18210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CJF12_RS18235	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CJF12_RS18255	COG1160	GTP binding
CJF12_RS18275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CJF12_RS18285	COG1040	competence protein
CJF12_RS18295	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CJF12_RS18300	COG2224	Isocitrate lyase
CJF12_RS18305	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CJF12_RS18320	COG0720	synthase
CJF12_RS18325	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJF12_RS18375	COG0488	(ABC) transporter
CJF12_RS18395	COG0544	peptidyl-prolyl cis-trans isomerase activity
CJF12_RS18420	COG0589	response to stress
CJF12_RS18440	COG1183	phosphatidylcholine synthase activity
CJF12_RS18470	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJF12_RS18470	COG0022	dehydrogenase e1 component
CJF12_RS18475	COG3158	transport of potassium into the cell
CJF12_RS18490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJF12_RS18505	COG1678	Uncharacterized ACR, COG1678
CJF12_RS18510	COG0259	pyridoxamine-phosphate oxidase activity
CJF12_RS18525	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CJF12_RS18540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CJF12_RS18545	COG1028	Short-chain dehydrogenase reductase Sdr
CJF12_RS18545	COG0604	alcohol dehydrogenase
CJF12_RS18545	COG3321	synthase
CJF12_RS18550	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS18580	COG0655	NAD(P)H dehydrogenase (quinone) activity
CJF12_RS18585	COG2207	Transcriptional regulator
CJF12_RS18585	COG1917	Cupin 2, conserved barrel domain protein
CJF12_RS18605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CJF12_RS18610	COG0339	signal peptide processing
CJF12_RS18635	COG0228	four-way junction DNA binding
CJF12_RS18640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CJF12_RS18660	COG0017	Asparaginyl-tRNA synthetase
CJF12_RS18670	COG0318	PFAM AMP-dependent synthetase and ligase
CJF12_RS18690	COG2326	polyphosphate kinase activity
CJF12_RS18700	COG0525	valine-tRNA ligase activity
CJF12_RS18710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJF12_RS18720	COG1418	mRNA catabolic process
CJF12_RS18780	COG1136	(ABC) transporter
CJF12_RS18785	COG1136	(ABC) transporter
CJF12_RS18785	COG0577	efflux transmembrane transporter activity
CJF12_RS18790	COG1136	(ABC) transporter
CJF12_RS18790	COG0577	efflux transmembrane transporter activity
CJF12_RS18800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJF12_RS18805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CJF12_RS18810	COG2137	regulation of response to DNA damage stimulus
CJF12_RS18830	COG3206	protein involved in exopolysaccharide biosynthesis
CJF12_RS18830	COG0489	protein tyrosine kinase activity
CJF12_RS18835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJF12_RS18840	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CJF12_RS18870	COG1216	Glycosyl transferase, family 2
CJF12_RS18870	COG0463	Glycosyl transferase, family 2
CJF12_RS18875	COG0110	maltose O-acetyltransferase activity
CJF12_RS18890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJF12_RS18895	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJF12_RS18900	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJF12_RS18905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJF12_RS18915	COG3206	protein involved in exopolysaccharide biosynthesis
CJF12_RS18915	COG0489	protein tyrosine kinase activity
CJF12_RS18925	COG1215	transferase activity, transferring glycosyl groups
CJF12_RS18960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJF12_RS18970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJF12_RS18990	COG0708	Exodeoxyribonuclease III
CJF12_RS19010	COG1078	dGTPase activity
CJF12_RS19015	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJF12_RS19020	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CJF12_RS19020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJF12_RS19030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CJF12_RS19035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJF12_RS19045	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CJF12_RS19055	COG1668	transmembrane transport
CJF12_RS19060	COG4152	abc transporter atp-binding protein
CJF12_RS19070	COG0113	porphobilinogen synthase activity
CJF12_RS19090	COG1137	ATPase activity
CJF12_RS19100	COG1959	2 iron, 2 sulfur cluster binding
CJF12_RS19105	COG1017	nitric oxide dioxygenase activity
CJF12_RS19105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CJF12_RS19120	COG1132	(ABC) transporter
CJF12_RS19125	COG2378	regulation of single-species biofilm formation
CJF12_RS19155	COG2365	Tyrosine phosphatase family
CJF12_RS19165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJF12_RS19170	COG0010	Belongs to the arginase family
CJF12_RS19175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJF12_RS19205	COG1301	dicarboxylic acid transport
CJF12_RS19215	COG3537	Alpha-1,2-mannosidase
CJF12_RS19225	COG0489	protein tyrosine kinase activity
CJF12_RS19230	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CJF12_RS19240	COG2197	response regulator
CJF12_RS19255	COG0248	Ppx GppA phosphatase
CJF12_RS19260	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CJF12_RS19285	COG0443	Heat shock 70 kDa protein
CJF12_RS19305	COG0366	Alpha amylase catalytic
CJF12_RS19335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CJF12_RS19340	COG1053	succinate dehydrogenase
CJF12_RS19350	COG0471	metal ion transport
CJF12_RS19360	COG4251	negative regulation of phosphorylation
CJF12_RS19380	COG2267	carboxylic ester hydrolase activity
CJF12_RS19395	COG1733	regulation of RNA biosynthetic process
CJF12_RS19405	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
CJF12_RS19410	COG2732	(Barnase) inhibitor
CJF12_RS19425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CJF12_RS19435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJF12_RS19450	COG0626	cystathionine gamma-synthase activity
CJF12_RS19475	COG0009	L-threonylcarbamoyladenylate synthase
CJF12_RS19480	COG0617	tRNA 3'-terminal CCA addition
CJF12_RS19480	COG0517	IMP dehydrogenase activity
CJF12_RS19480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CJF12_RS19545	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CJF12_RS19555	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CJF12_RS19560	COG0402	S-adenosylhomocysteine deaminase activity
CJF12_RS19570	COG0402	S-adenosylhomocysteine deaminase activity
CJF12_RS19590	COG0745	RESPONSE REGULATOR receiver
CJF12_RS19595	COG5002	protein histidine kinase activity
CJF12_RS19630	COG0308	aminopeptidase N
CJF12_RS19640	COG3425	synthase
CJF12_RS19645	COG4771	TonB-dependent receptor
CJF12_RS19660	COG1012	belongs to the aldehyde dehydrogenase family
CJF12_RS19675	COG0484	heat shock protein binding
CJF12_RS19700	COG3876	Protein conserved in bacteria
CJF12_RS19735	COG2909	trisaccharide binding
CJF12_RS19755	COG1484	DNA-dependent DNA replication
CJF12_RS19760	COG4584	PFAM Integrase catalytic