locus-tag	class	description
EG350_RS00005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EG350_RS00040	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EG350_RS00090	COG0481	GTPase activity
EG350_RS00105	COG1595	DNA-templated transcription, initiation
EG350_RS00115	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EG350_RS00120	COG0424	maF-like protein
EG350_RS00130	COG1214	PFAM Peptidase M22, glycoprotease
EG350_RS00140	COG4221	oxidoreductase activity
EG350_RS00145	COG0792	nuclease activity
EG350_RS00150	COG1619	proteins homologs of microcin C7 resistance protein MccF
EG350_RS00160	COG0557	exoribonuclease II activity
EG350_RS00165	COG0698	ribose 5-phosphate isomerase
EG350_RS00170	COG0126	phosphoglycerate kinase activity
EG350_RS00180	COG0445	tRNA wobble uridine modification
EG350_RS00185	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EG350_RS00200	COG1435	thymidine kinase activity
EG350_RS00210	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EG350_RS00220	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS00225	COG0516	GMP reductase activity
EG350_RS00245	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EG350_RS00250	COG0793	Belongs to the peptidase S41A family
EG350_RS00255	COG2032	superoxide dismutase activity
EG350_RS00270	COG3275	phosphorelay sensor kinase activity
EG350_RS00280	COG2020	methyltransferase activity
EG350_RS00295	COG3279	Response regulator of the LytR AlgR family
EG350_RS00315	COG0482	sulfurtransferase activity
EG350_RS00325	COG0542	response to heat
EG350_RS00340	COG2166	iron-sulfur cluster assembly
EG350_RS00390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EG350_RS00395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EG350_RS00420	COG0811	peptide transport
EG350_RS00440	COG2715	membrane protein required for spore maturation
EG350_RS00450	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EG350_RS00460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EG350_RS00475	COG3781	membrane
EG350_RS00485	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EG350_RS00525	COG2081	HI0933 family
EG350_RS00535	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EG350_RS00545	COG2195	Cleaves the N-terminal amino acid of tripeptides
EG350_RS00560	COG2151	metal-sulfur cluster biosynthetic enzyme
EG350_RS00570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG350_RS00580	COG1595	DNA-templated transcription, initiation
EG350_RS00595	COG0606	chelatase, subunit chli
EG350_RS00610	COG3591	Belongs to the peptidase S1B family
EG350_RS00655	COG3422	double-strand break repair
EG350_RS00670	COG4585	Histidine kinase
EG350_RS00690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EG350_RS00730	COG0387	Pfam Sodium calcium exchanger
EG350_RS00770	COG0758	DNA mediated transformation
EG350_RS00785	COG0719	Fe-S assembly protein
EG350_RS00790	COG0396	ATPase activity
EG350_RS00800	COG0719	Fe-S assembly protein
EG350_RS00805	COG0316	Belongs to the HesB IscA family
EG350_RS00815	COG2321	neutral zinc metallopeptidase
EG350_RS00820	COG1368	sulfuric ester hydrolase activity
EG350_RS00825	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EG350_RS00870	COG0437	4 iron, 4 sulfur cluster binding
EG350_RS00895	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EG350_RS00900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EG350_RS00910	COG1774	PSP1 C-terminal conserved region
EG350_RS00925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EG350_RS00930	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EG350_RS00960	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EG350_RS00960	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EG350_RS00970	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EG350_RS00975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EG350_RS00980	COG1505	serine-type exopeptidase activity
EG350_RS00985	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EG350_RS00985	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EG350_RS00995	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EG350_RS01000	COG1690	Belongs to the RtcB family
EG350_RS01005	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EG350_RS01025	COG1703	isobutyryl-CoA mutase activity
EG350_RS01055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EG350_RS01060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EG350_RS01065	COG0602	queuosine metabolic process
EG350_RS01070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EG350_RS01100	COG1960	acyl-CoA dehydrogenase activity
EG350_RS01115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EG350_RS01120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EG350_RS01125	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EG350_RS01130	COG0247	lactate metabolic process
EG350_RS01130	COG2181	nitrate reductase activity
EG350_RS01135	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EG350_RS01135	COG0165	Argininosuccinate lyase
EG350_RS01140	COG0247	lactate metabolic process
EG350_RS01140	COG2181	nitrate reductase activity
EG350_RS01170	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EG350_RS01190	COG0348	domain, Protein
EG350_RS01215	COG2217	Heavy metal translocating P-type atpase
EG350_RS01220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EG350_RS01225	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EG350_RS01235	COG0564	pseudouridine synthase activity
EG350_RS01255	COG0351	phosphomethylpyrimidine kinase
EG350_RS01260	COG0352	thiamine-phosphate diphosphorylase activity
EG350_RS01265	COG2022	thiamine diphosphate biosynthetic process
EG350_RS01270	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EG350_RS01275	COG4974	Belongs to the 'phage' integrase family
EG350_RS01355	COG3275	phosphorelay sensor kinase activity
EG350_RS01360	COG3279	Response regulator of the LytR AlgR family
EG350_RS01365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EG350_RS01385	COG1607	acyl-coa hydrolase
EG350_RS01395	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EG350_RS01400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EG350_RS01415	COG0494	nUDIX hydrolase
EG350_RS01420	COG4974	Belongs to the 'phage' integrase family
EG350_RS01430	COG1024	Enoyl-CoA hydratase
EG350_RS01445	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EG350_RS01465	COG0180	Tryptophanyl-tRNA synthetase
EG350_RS01475	COG2949	membrane
EG350_RS01480	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EG350_RS01495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EG350_RS01500	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EG350_RS01505	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EG350_RS01520	COG2986	histidine ammonia-lyase
EG350_RS01530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EG350_RS01535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG350_RS01545	COG0644	oxidoreductase
EG350_RS01565	COG1215	transferase activity, transferring glycosyl groups
EG350_RS01575	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EG350_RS01600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EG350_RS01605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG350_RS01630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EG350_RS01650	COG1131	(ABC) transporter
EG350_RS01670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EG350_RS01675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EG350_RS01685	COG2409	Drug exporters of the RND superfamily
EG350_RS01715	COG1442	glycosyl transferase family 8
EG350_RS01715	COG1216	Glycosyl transferase, family 2
EG350_RS01720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EG350_RS01740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EG350_RS01800	COG3511	phospholipase C
EG350_RS01810	COG0300	oxidoreductase activity
EG350_RS01815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EG350_RS01835	COG0254	rRNA binding
EG350_RS01845	COG1595	DNA-templated transcription, initiation
EG350_RS01865	COG0516	GMP reductase activity
EG350_RS01865	COG0517	IMP dehydrogenase activity
EG350_RS01870	COG4249	Peptidase C14 caspase catalytic subunit p20
EG350_RS01885	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EG350_RS01915	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EG350_RS01915	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EG350_RS01915	COG1703	isobutyryl-CoA mutase activity
EG350_RS01930	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EG350_RS01935	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EG350_RS01940	COG0052	Belongs to the universal ribosomal protein uS2 family
EG350_RS01955	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EG350_RS01995	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EG350_RS02005	COG0825	malonyl-CoA metabolic process
EG350_RS02010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EG350_RS02025	COG1216	Glycosyl transferase, family 2
EG350_RS02035	COG0463	Glycosyl transferase, family 2
EG350_RS02060	COG0439	Biotin carboxylase
EG350_RS02065	COG0511	ligase activity, forming carbon-carbon bonds
EG350_RS02070	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EG350_RS02080	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EG350_RS02090	COG5000	phosphorelay sensor kinase activity
EG350_RS02095	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EG350_RS02100	COG2884	Cell division ATP-binding protein ftsE
EG350_RS02105	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EG350_RS02110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EG350_RS02120	COG0596	Alpha beta hydrolase
EG350_RS02120	COG0508	dehydrogenase complex catalyzes the overall conversion of
EG350_RS02140	COG0037	tRNA processing
EG350_RS02165	COG1519	Transferase
EG350_RS02175	COG1215	transferase activity, transferring glycosyl groups
EG350_RS02190	COG0495	leucyl-tRNA aminoacylation
EG350_RS02230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EG350_RS02255	COG1132	(ABC) transporter
EG350_RS02260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EG350_RS02270	COG1862	Preprotein translocase
EG350_RS02275	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS02280	COG3285	dna ligase
EG350_RS02280	COG1793	dna ligase
EG350_RS02290	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EG350_RS02300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EG350_RS02305	COG0534	Mate efflux family protein
EG350_RS02325	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EG350_RS02330	COG0658	competence protein
EG350_RS02330	COG2333	competence protein COMEC
EG350_RS02340	COG1053	succinate dehydrogenase
EG350_RS02345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EG350_RS02355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EG350_RS02380	COG0237	dephospho-CoA kinase activity
EG350_RS02385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG350_RS02390	COG2255	four-way junction helicase activity
EG350_RS02395	COG1228	amidohydrolase
EG350_RS02405	COG1012	belongs to the aldehyde dehydrogenase family
EG350_RS02410	COG0469	pyruvate kinase activity
EG350_RS02420	COG0571	ribonuclease III activity
EG350_RS02425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EG350_RS02430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG350_RS02515	COG2855	membrane
EG350_RS02520	COG0583	DNA-binding transcription factor activity
EG350_RS02540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EG350_RS02545	COG4974	Belongs to the 'phage' integrase family
EG350_RS02595	COG5002	protein histidine kinase activity
EG350_RS02620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EG350_RS02660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EG350_RS02665	COG0081	regulation of translation
EG350_RS02670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EG350_RS02675	COG0222	ribosome binding
EG350_RS02680	COG0085	RNA polymerase activity
EG350_RS02685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EG350_RS02725	COG0477	Major facilitator Superfamily
EG350_RS02740	COG1132	(ABC) transporter
EG350_RS02745	COG0101	tRNA pseudouridine synthase activity
EG350_RS02750	COG1663	tetraacyldisaccharide 4'-kinase activity
EG350_RS02755	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EG350_RS02760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG350_RS02765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EG350_RS02770	COG0366	Alpha amylase catalytic
EG350_RS02775	COG2272	Belongs to the type-B carboxylesterase lipase family
EG350_RS02820	COG1733	regulation of RNA biosynthetic process
EG350_RS02860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EG350_RS02895	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EG350_RS02905	COG2353	YceI-like domain
EG350_RS02915	COG0504	CTP synthase activity
EG350_RS02920	COG0706	membrane insertase activity
EG350_RS02925	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EG350_RS02930	COG4771	TonB-dependent receptor
EG350_RS02940	COG0018	arginyl-trna synthetase
EG350_RS03005	COG0318	PFAM AMP-dependent synthetase and ligase
EG350_RS03010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EG350_RS03035	COG0326	Molecular chaperone. Has ATPase activity
EG350_RS03040	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EG350_RS03060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EG350_RS03065	COG0205	6-phosphofructokinase activity
EG350_RS03085	COG2363	Small membrane protein
EG350_RS03095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EG350_RS03100	COG1132	(ABC) transporter
EG350_RS03115	COG0045	succinate-CoA ligase (ADP-forming) activity
EG350_RS03130	COG3264	Mechanosensitive ion channel
EG350_RS03130	COG1196	nuclear chromosome segregation
EG350_RS03135	COG0450	alkyl hydroperoxide reductase
EG350_RS03150	COG4206	TonB-dependent receptor
EG350_RS03155	COG0673	inositol 2-dehydrogenase activity
EG350_RS03160	COG0488	(ABC) transporter
EG350_RS03195	COG1252	NADH dehydrogenase
EG350_RS03200	COG0336	Belongs to the RNA methyltransferase TrmD family
EG350_RS03210	COG1522	sequence-specific DNA binding
EG350_RS03215	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EG350_RS03245	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EG350_RS03245	COG0284	orotidine-5'-phosphate decarboxylase activity
EG350_RS03265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EG350_RS03290	COG4974	Belongs to the 'phage' integrase family
EG350_RS03330	COG0210	DNA helicase
EG350_RS03335	COG1401	restriction endodeoxyribonuclease activity
EG350_RS03395	COG0739	heme binding
EG350_RS03455	COG0484	heat shock protein binding
EG350_RS03500	COG3620	sequence-specific DNA binding
EG350_RS03505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EG350_RS03510	COG0587	DNA-directed DNA polymerase activity
EG350_RS03645	COG1506	peptidase
EG350_RS03650	COG0702	epimerase
EG350_RS03655	COG4771	TonB-dependent receptor
EG350_RS03735	COG0745	RESPONSE REGULATOR receiver
EG350_RS03740	COG5002	protein histidine kinase activity
EG350_RS03765	COG0671	phosphoesterase, PA-phosphatase related
EG350_RS03785	COG1368	sulfuric ester hydrolase activity
EG350_RS03790	COG0671	phosphoesterase, PA-phosphatase related
EG350_RS03825	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EG350_RS03835	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EG350_RS03840	COG0194	GDP metabolic process
EG350_RS03845	COG1561	YicC-like family, N-terminal region
EG350_RS03850	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EG350_RS03865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EG350_RS03905	COG4677	pectinesterase activity
EG350_RS03920	COG2755	lipolytic protein G-D-S-L family
EG350_RS03945	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EG350_RS03960	COG0702	epimerase
EG350_RS03965	COG1629	transport
EG350_RS03970	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EG350_RS03975	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS03980	COG1904	glucuronate isomerase
EG350_RS03990	COG0800	Aldolase
EG350_RS03995	COG2271	Major facilitator Superfamily
EG350_RS04000	COG0246	Mannitol dehydrogenase
EG350_RS04005	COG2721	sulfolactate sulfo-lyase activity
EG350_RS04040	COG0813	purine-nucleoside phosphorylase activity
EG350_RS04060	COG0714	Associated with various cellular activities
EG350_RS04150	COG0659	secondary active sulfate transmembrane transporter activity
EG350_RS04170	COG3853	Toxic anion resistance protein (TelA)
EG350_RS04220	COG0545	Peptidyl-prolyl cis-trans isomerase
EG350_RS04230	COG1959	2 iron, 2 sulfur cluster binding
EG350_RS04235	COG2910	NAD(P)H-binding
EG350_RS04240	COG0739	heme binding
EG350_RS04245	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EG350_RS04250	COG0579	oxidoreductase
EG350_RS04265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EG350_RS04290	COG0737	Belongs to the 5'-nucleotidase family
EG350_RS04300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EG350_RS04320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EG350_RS04325	COG4232	protein-disulfide reductase activity
EG350_RS04330	COG3104	oligopeptide transport
EG350_RS04335	COG3104	oligopeptide transport
EG350_RS04340	COG3104	oligopeptide transport
EG350_RS04355	COG1506	peptidase
EG350_RS04355	COG0823	Involved in the tonB-independent uptake of proteins
EG350_RS04390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EG350_RS04410	COG4974	Belongs to the 'phage' integrase family
EG350_RS04495	COG2259	Doxx family
EG350_RS04500	COG0671	phosphoesterase, PA-phosphatase related
EG350_RS04515	COG0659	secondary active sulfate transmembrane transporter activity
EG350_RS04520	COG0798	PFAM Bile acid sodium symporter
EG350_RS04540	COG2072	flavoprotein involved in K transport
EG350_RS04555	COG0640	Transcriptional regulator
EG350_RS04565	COG0582	viral genome integration into host DNA
EG350_RS04570	COG4974	Belongs to the 'phage' integrase family
EG350_RS04635	COG1204	response to ionizing radiation
EG350_RS04650	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EG350_RS04670	COG0018	arginyl-trna synthetase
EG350_RS04710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EG350_RS04725	COG0745	RESPONSE REGULATOR receiver
EG350_RS04730	COG5002	protein histidine kinase activity
EG350_RS04740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EG350_RS04795	COG0551	DNA topoisomerase type I activity
EG350_RS04795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EG350_RS04820	COG0069	glutamate synthase activity
EG350_RS04830	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EG350_RS04835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EG350_RS04855	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EG350_RS04860	COG0297	glycogen (starch) synthase activity
EG350_RS04870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EG350_RS04875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EG350_RS04935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EG350_RS04950	COG0252	asparaginase activity
EG350_RS05035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EG350_RS05045	COG1522	sequence-specific DNA binding
EG350_RS05055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EG350_RS05065	COG4145	pantothenate transmembrane transporter activity
EG350_RS05090	COG1741	Belongs to the pirin family
EG350_RS05105	COG0477	Major facilitator Superfamily
EG350_RS05115	COG0367	asparagine synthase
EG350_RS05125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EG350_RS05125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EG350_RS05130	COG2824	Alkylphosphonate utilization operon protein PhnA
EG350_RS05145	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EG350_RS05150	COG4999	Histidine kinase
EG350_RS05150	COG3850	Histidine kinase
EG350_RS05150	COG3437	response regulator, receiver
EG350_RS05150	COG2205	protein histidine kinase activity
EG350_RS05165	COG0492	ferredoxin-NADP+ reductase activity
EG350_RS05180	COG1611	Belongs to the LOG family
EG350_RS05195	COG2195	Cleaves the N-terminal amino acid of tripeptides
EG350_RS05210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EG350_RS05240	COG0612	Peptidase, M16
EG350_RS05245	COG0612	Peptidase, M16
EG350_RS05250	COG5002	protein histidine kinase activity
EG350_RS05255	COG0745	RESPONSE REGULATOR receiver
EG350_RS05265	COG0210	DNA helicase
EG350_RS05320	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EG350_RS05325	COG0427	acetyl-CoA hydrolase
EG350_RS05330	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EG350_RS05335	COG4771	TonB-dependent receptor
EG350_RS05355	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EG350_RS05370	COG2249	NAD(P)H dehydrogenase (quinone) activity
EG350_RS05375	COG0583	DNA-binding transcription factor activity
EG350_RS05380	COG0656	L-ascorbic acid biosynthetic process
EG350_RS05395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EG350_RS05440	COG1530	ribonuclease E activity
EG350_RS05445	COG0776	regulation of translation
EG350_RS05450	COG2197	response regulator
EG350_RS05480	COG3179	chitinase
EG350_RS05505	COG0542	response to heat
EG350_RS05515	COG3501	Rhs element vgr protein
EG350_RS05565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EG350_RS05565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EG350_RS05570	COG0612	Peptidase, M16
EG350_RS05580	COG4717	serine-type aminopeptidase activity
EG350_RS05585	COG1285	pathogenesis
EG350_RS05595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EG350_RS05605	COG4771	TonB-dependent receptor
EG350_RS05620	COG0300	oxidoreductase activity
EG350_RS05625	COG2264	protein methyltransferase activity
EG350_RS05660	COG3023	N-Acetylmuramoyl-L-alanine amidase
EG350_RS05665	COG1027	Aspartate ammonia-lyase
EG350_RS05710	COG0306	phosphate transporter
EG350_RS05730	COG0084	hydrolase, TatD family'
EG350_RS05735	COG0513	Belongs to the DEAD box helicase family
EG350_RS05745	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EG350_RS05750	COG0563	adenylate kinase activity
EG350_RS05755	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EG350_RS05765	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EG350_RS05775	COG1192	Involved in chromosome partitioning
EG350_RS05780	COG1475	DNA binding
EG350_RS05790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EG350_RS05795	COG0681	Belongs to the peptidase S26 family
EG350_RS05820	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EG350_RS05825	COG0277	FAD linked oxidase domain protein
EG350_RS05840	COG1104	cysteine desulfurase activity
EG350_RS05860	COG4974	Belongs to the 'phage' integrase family
EG350_RS05870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EG350_RS05900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG350_RS05900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EG350_RS05910	COG0500	methyltransferase
EG350_RS05920	COG3118	belongs to the thioredoxin family
EG350_RS05950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG350_RS05955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG350_RS05965	COG0737	Belongs to the 5'-nucleotidase family
EG350_RS06015	COG0484	heat shock protein binding
EG350_RS06075	COG0739	heme binding
EG350_RS06095	COG0827	DNA restriction-modification system
EG350_RS06115	COG3781	membrane
EG350_RS06125	COG1368	sulfuric ester hydrolase activity
EG350_RS06135	COG2217	Heavy metal translocating P-type atpase
EG350_RS06140	COG0671	phosphoesterase, PA-phosphatase related
EG350_RS06185	COG0019	diaminopimelate decarboxylase activity
EG350_RS06205	COG1595	DNA-templated transcription, initiation
EG350_RS06270	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EG350_RS06285	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EG350_RS06290	COG2814	Major facilitator Superfamily
EG350_RS06325	COG3275	phosphorelay sensor kinase activity
EG350_RS06330	COG3279	Response regulator of the LytR AlgR family
EG350_RS06345	COG1058	Belongs to the CinA family
EG350_RS06345	COG1546	Belongs to the CinA family
EG350_RS06350	COG3590	peptidase
EG350_RS06355	COG3590	peptidase
EG350_RS06375	COG1194	a g-specific adenine glycosylase
EG350_RS06390	COG0346	lactoylglutathione lyase activity
EG350_RS06405	COG0730	response to heat
EG350_RS06415	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EG350_RS06420	COG0475	glutathione-regulated potassium exporter activity
EG350_RS06420	COG0589	response to stress
EG350_RS06430	COG0697	spore germination
EG350_RS06435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EG350_RS06445	COG4682	membrane
EG350_RS06450	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EG350_RS06460	COG1289	transmembrane transporter activity
EG350_RS06520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EG350_RS06560	COG1309	transcriptional regulator
EG350_RS06575	COG2814	Major facilitator Superfamily
EG350_RS06595	COG0598	Magnesium transport protein CorA
EG350_RS06600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EG350_RS06610	COG3118	belongs to the thioredoxin family
EG350_RS06625	COG1012	belongs to the aldehyde dehydrogenase family
EG350_RS06645	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS06650	COG1733	regulation of RNA biosynthetic process
EG350_RS06660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EG350_RS06665	COG4974	Belongs to the 'phage' integrase family
EG350_RS06840	COG1431	PFAM Stem cell self-renewal protein Piwi
EG350_RS06895	COG0745	RESPONSE REGULATOR receiver
EG350_RS06900	COG0642	Histidine kinase
EG350_RS06910	COG1368	sulfuric ester hydrolase activity
EG350_RS06915	COG0671	phosphoesterase, PA-phosphatase related
EG350_RS06955	COG0702	epimerase
EG350_RS06960	COG0702	epimerase
EG350_RS07005	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EG350_RS07010	COG1917	Cupin 2, conserved barrel domain protein
EG350_RS07010	COG4977	sequence-specific DNA binding
EG350_RS07030	COG0667	Aldo Keto reductase
EG350_RS07035	COG0667	Aldo Keto reductase
EG350_RS07070	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EG350_RS07085	COG0551	DNA topoisomerase type I activity
EG350_RS07085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EG350_RS07125	COG1396	sequence-specific DNA binding
EG350_RS07140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EG350_RS07145	COG0732	type I restriction modification DNA specificity domain
EG350_RS07170	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EG350_RS07185	COG4804	nuclease activity
EG350_RS07210	COG0784	Response regulator, receiver
EG350_RS07210	COG2205	protein histidine kinase activity
EG350_RS07210	COG2198	Histidine kinase
EG350_RS07215	COG2197	response regulator
EG350_RS07220	COG1522	sequence-specific DNA binding
EG350_RS07240	COG1472	Belongs to the glycosyl hydrolase 3 family
EG350_RS07245	COG1464	Belongs to the NlpA lipoprotein family
EG350_RS07250	COG2011	ABC-type metal ion transport system permease component
EG350_RS07255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EG350_RS07260	COG0346	lactoylglutathione lyase activity
EG350_RS07270	COG0346	lactoylglutathione lyase activity
EG350_RS07285	COG0025	NhaP-type Na H and K H
EG350_RS07300	COG1741	Belongs to the pirin family
EG350_RS07315	COG1950	PFAM Membrane protein of
EG350_RS07320	COG1506	peptidase
EG350_RS07320	COG0823	Involved in the tonB-independent uptake of proteins
EG350_RS07345	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EG350_RS07350	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EG350_RS07365	COG0142	geranyltranstransferase activity
EG350_RS07375	COG0022	dehydrogenase e1 component
EG350_RS07385	COG1733	regulation of RNA biosynthetic process
EG350_RS07390	COG1902	pentaerythritol trinitrate reductase activity
EG350_RS07440	COG1090	epimerase
EG350_RS07455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EG350_RS07475	COG1131	(ABC) transporter
EG350_RS07495	COG1917	Cupin 2, conserved barrel domain protein
EG350_RS07495	COG4977	sequence-specific DNA binding
EG350_RS07705	COG5002	protein histidine kinase activity
EG350_RS07710	COG2205	protein histidine kinase activity
EG350_RS07720	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EG350_RS07735	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EG350_RS07745	COG2204	response regulator
EG350_RS07755	COG2323	membrane
EG350_RS07780	COG0387	Pfam Sodium calcium exchanger
EG350_RS07790	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EG350_RS07825	COG0671	phosphoesterase, PA-phosphatase related
EG350_RS07825	COG2453	phosphatase
EG350_RS07835	COG0315	cyclic pyranopterin monophosphate synthase activity
EG350_RS07840	COG0314	molybdopterin synthase activity
EG350_RS07845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EG350_RS07860	COG0303	'Molybdopterin
EG350_RS07865	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EG350_RS07875	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EG350_RS07880	COG2080	2 iron, 2 sulfur cluster binding
EG350_RS07885	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EG350_RS07890	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EG350_RS07895	COG2080	2 iron, 2 sulfur cluster binding
EG350_RS07900	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EG350_RS07905	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EG350_RS07920	COG2267	carboxylic ester hydrolase activity
EG350_RS07925	COG1335	isochorismatase
EG350_RS07935	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EG350_RS07940	COG1228	amidohydrolase
EG350_RS07950	COG0783	Belongs to the Dps family
EG350_RS07970	COG2204	response regulator
EG350_RS07975	COG3548	integral membrane protein
EG350_RS07980	COG3604	Transcriptional regulator
EG350_RS07990	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS08000	COG4221	oxidoreductase activity
EG350_RS08010	COG1733	regulation of RNA biosynthetic process
EG350_RS08020	COG1064	alcohol dehydrogenase
EG350_RS08035	COG1917	Cupin 2, conserved barrel domain protein
EG350_RS08035	COG4977	sequence-specific DNA binding
EG350_RS08045	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS08055	COG1917	Cupin 2, conserved barrel domain protein
EG350_RS08055	COG4977	sequence-specific DNA binding
EG350_RS08060	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS08065	COG4977	sequence-specific DNA binding
EG350_RS08065	COG1917	Cupin 2, conserved barrel domain protein
EG350_RS08075	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS08090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EG350_RS08105	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EG350_RS08170	COG1428	Deoxynucleoside kinase
EG350_RS08175	COG1393	Belongs to the ArsC family
EG350_RS08190	COG1629	transport
EG350_RS08195	COG0702	epimerase
EG350_RS08230	COG3279	Response regulator of the LytR AlgR family
EG350_RS08235	COG3275	phosphorelay sensor kinase activity
EG350_RS08255	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EG350_RS08285	COG0592	DNA-directed DNA polymerase activity
EG350_RS08290	COG0739	heme binding
EG350_RS08315	COG1250	3-hydroxyacyl-CoA dehydrogenase
EG350_RS08340	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EG350_RS08345	COG0335	large ribosomal subunit rRNA binding
EG350_RS08360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EG350_RS08365	COG1132	(ABC) transporter
EG350_RS08375	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EG350_RS08380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EG350_RS08385	COG0730	response to heat
EG350_RS08390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EG350_RS08390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG350_RS08405	COG1446	asparaginase
EG350_RS08410	COG3142	Participates in the control of copper homeostasis
EG350_RS08420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EG350_RS08425	COG2027	D-alanyl-D-alanine carboxypeptidase
EG350_RS08440	COG0156	8-amino-7-oxononanoate synthase activity
EG350_RS08450	COG1981	membrane
EG350_RS08525	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS08550	COG1191	sigma factor activity
EG350_RS08565	COG0484	heat shock protein binding
EG350_RS08570	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EG350_RS08570	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EG350_RS08580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EG350_RS08590	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EG350_RS08610	COG0531	amino acid
EG350_RS08650	COG2351	hydroxyisourate hydrolase activity
EG350_RS08685	COG3046	protein related to deoxyribodipyrimidine photolyase
EG350_RS08690	COG0415	Belongs to the DNA photolyase family
EG350_RS08710	COG0463	Glycosyl transferase, family 2
EG350_RS08715	COG1058	Belongs to the CinA family
EG350_RS08715	COG1546	Belongs to the CinA family
EG350_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS08755	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EG350_RS08755	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EG350_RS08760	COG0702	epimerase
EG350_RS08780	COG2183	response to ionizing radiation
EG350_RS08840	COG1217	gtp-binding protein TYPA
EG350_RS08845	COG1649	PFAM Uncharacterised BCR, COG1649
EG350_RS08850	COG1733	regulation of RNA biosynthetic process
EG350_RS08855	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS08860	COG1528	Iron-storage protein
EG350_RS08870	COG0012	GTP binding
EG350_RS08885	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS08890	COG0436	Aminotransferase
EG350_RS08920	COG2890	protein-(glutamine-N5) methyltransferase activity
EG350_RS08925	COG3022	response to hydroperoxide
EG350_RS08930	COG0009	L-threonylcarbamoyladenylate synthase
EG350_RS08985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EG350_RS09000	COG3340	Belongs to the peptidase S51 family
EG350_RS09005	COG2027	D-alanyl-D-alanine carboxypeptidase
EG350_RS09010	COG3852	Histidine kinase
EG350_RS09025	COG0805	protein transport
EG350_RS09030	COG0517	IMP dehydrogenase activity
EG350_RS09030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EG350_RS09035	COG0514	ATP-dependent DNA helicase (RecQ)
EG350_RS09040	COG0438	transferase activity, transferring glycosyl groups
EG350_RS09050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EG350_RS09060	COG2996	Protein conserved in bacteria
EG350_RS09105	COG0494	nUDIX hydrolase
EG350_RS09110	COG1090	epimerase
EG350_RS09125	COG0629	single-stranded DNA binding
EG350_RS09135	COG0124	histidyl-tRNA synthetase
EG350_RS09145	COG1446	asparaginase
EG350_RS09150	COG4242	Belongs to the peptidase S51 family
EG350_RS09170	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EG350_RS09190	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EG350_RS09200	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EG350_RS09205	COG0297	glycogen (starch) synthase activity
EG350_RS09210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EG350_RS09225	COG0508	dehydrogenase complex catalyzes the overall conversion of
EG350_RS09230	COG2967	ApaG domain
EG350_RS09260	COG0359	binds to the 23S rRNA
EG350_RS09265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EG350_RS09270	COG0360	Binds together with S18 to 16S ribosomal RNA
EG350_RS09280	COG0508	dehydrogenase complex catalyzes the overall conversion of
EG350_RS09290	COG1702	phosphate starvation-inducible protein PhoH
EG350_RS09325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EG350_RS09330	COG0356	it plays a direct role in the translocation of protons across the membrane
EG350_RS09335	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EG350_RS09340	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EG350_RS09345	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EG350_RS09350	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EG350_RS09355	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EG350_RS09360	COG1253	flavin adenine dinucleotide binding
EG350_RS09375	COG0572	uridine kinase
EG350_RS09385	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EG350_RS09385	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EG350_RS09420	COG0300	oxidoreductase activity
EG350_RS09430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EG350_RS09440	COG2211	Major facilitator Superfamily
EG350_RS09465	COG0183	Belongs to the thiolase family
EG350_RS09470	COG2270	Major facilitator Superfamily
EG350_RS09510	COG0531	amino acid
EG350_RS09530	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EG350_RS09540	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EG350_RS09545	COG1187	pseudouridine synthase activity
EG350_RS09555	COG1575	Belongs to the MenA family. Type 1 subfamily
EG350_RS09560	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EG350_RS09590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EG350_RS09595	COG0436	Aminotransferase
EG350_RS09605	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EG350_RS09615	COG0386	Belongs to the glutathione peroxidase family
EG350_RS09640	COG0196	riboflavin kinase activity
EG350_RS09645	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EG350_RS09665	COG0156	8-amino-7-oxononanoate synthase activity
EG350_RS09700	COG2814	Major facilitator Superfamily
EG350_RS09705	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EG350_RS09710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EG350_RS09735	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EG350_RS09745	COG1801	Protein of unknown function DUF72
EG350_RS09750	COG2217	Heavy metal translocating P-type atpase
EG350_RS09760	COG1607	acyl-coa hydrolase
EG350_RS09765	COG0724	RNA recognition motif
EG350_RS09785	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EG350_RS09795	COG1136	(ABC) transporter
EG350_RS09810	COG2003	Belongs to the UPF0758 family
EG350_RS09825	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EG350_RS09830	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EG350_RS09850	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EG350_RS09860	COG1321	iron dependent repressor
EG350_RS09885	COG0640	Transcriptional regulator
EG350_RS09905	COG0561	phosphatase activity
EG350_RS09925	COG1252	NADH dehydrogenase
EG350_RS09935	COG0667	Aldo Keto reductase
EG350_RS09950	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EG350_RS09965	COG2323	membrane
EG350_RS09970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EG350_RS09975	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EG350_RS09980	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EG350_RS10000	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EG350_RS10000	COG1793	dna ligase
EG350_RS10005	COG1793	dna ligase
EG350_RS10015	COG1247	-acetyltransferase
EG350_RS10025	COG1011	Hydrolase
EG350_RS10030	COG1506	peptidase
EG350_RS10040	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EG350_RS10065	COG1960	acyl-CoA dehydrogenase activity
EG350_RS10105	COG0066	3-isopropylmalate dehydratase activity
EG350_RS10110	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EG350_RS10115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EG350_RS10125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EG350_RS10130	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EG350_RS10145	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EG350_RS10150	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EG350_RS10155	COG2234	aminopeptidase activity
EG350_RS10160	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EG350_RS10160	COG0140	phosphoribosyl-ATP diphosphatase activity
EG350_RS10165	COG0107	imidazoleglycerol-phosphate synthase activity
EG350_RS10170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EG350_RS10180	COG0131	Imidazoleglycerol-phosphate dehydratase
EG350_RS10185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EG350_RS10190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EG350_RS10195	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EG350_RS10200	COG0438	transferase activity, transferring glycosyl groups
EG350_RS10210	COG0463	Glycosyl transferase, family 2
EG350_RS10220	COG2171	N-acyltransferase activity
EG350_RS10225	COG0791	NLP P60 protein
EG350_RS10240	COG1538	Outer membrane efflux protein
EG350_RS10275	COG1012	belongs to the aldehyde dehydrogenase family
EG350_RS10295	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EG350_RS10295	COG1333	cytochrome c biogenesis protein
EG350_RS10300	COG1674	ftsk spoiiie
EG350_RS10325	COG0233	cytoplasmic translational termination
EG350_RS10330	COG0528	UMP kinase activity
EG350_RS10360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EG350_RS10370	COG2949	membrane
EG350_RS10380	COG3118	belongs to the thioredoxin family
EG350_RS10390	COG1120	ATPase activity
EG350_RS10400	COG1250	3-hydroxyacyl-CoA dehydrogenase
EG350_RS10400	COG1024	Enoyl-CoA hydratase
EG350_RS10405	COG0183	Belongs to the thiolase family
EG350_RS10415	COG1960	acyl-CoA dehydrogenase activity
EG350_RS10440	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EG350_RS10445	COG1104	cysteine desulfurase activity
EG350_RS10470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EG350_RS10485	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EG350_RS10490	COG3871	stress protein (general stress protein 26)
EG350_RS10500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EG350_RS10500	COG0723	plastoquinol--plastocyanin reductase activity
EG350_RS10505	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS10510	COG0300	oxidoreductase activity
EG350_RS10515	COG1058	Belongs to the CinA family
EG350_RS10515	COG1546	Belongs to the CinA family
EG350_RS10520	COG1063	alcohol dehydrogenase
EG350_RS10530	COG3685	Protein conserved in bacteria
EG350_RS10555	COG3118	belongs to the thioredoxin family
EG350_RS10565	COG2318	DinB family
EG350_RS10570	COG1335	isochorismatase
EG350_RS10595	COG2323	membrane
EG350_RS10625	COG1363	Peptidase, m42
EG350_RS10630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EG350_RS10635	COG0105	UTP biosynthetic process
EG350_RS10640	COG1162	GTPase activity
EG350_RS10645	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EG350_RS10645	COG1605	Chorismate mutase
EG350_RS10655	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EG350_RS10665	COG0156	8-amino-7-oxononanoate synthase activity
EG350_RS10695	COG0561	phosphatase activity
EG350_RS10710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EG350_RS10715	COG3685	Protein conserved in bacteria
EG350_RS10720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EG350_RS10725	COG1522	sequence-specific DNA binding
EG350_RS10730	COG1858	cytochrome C peroxidase
EG350_RS10745	COG0784	Response regulator, receiver
EG350_RS10745	COG2205	protein histidine kinase activity
EG350_RS10755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EG350_RS10760	COG3437	response regulator, receiver
EG350_RS10765	COG2205	protein histidine kinase activity
EG350_RS10765	COG0784	Response regulator, receiver
EG350_RS10770	COG5002	protein histidine kinase activity
EG350_RS10790	COG2076	Multidrug Resistance protein
EG350_RS10800	COG2226	methyltransferase
EG350_RS10820	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EG350_RS10845	COG0813	purine-nucleoside phosphorylase activity
EG350_RS10865	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EG350_RS10885	COG1472	Belongs to the glycosyl hydrolase 3 family
EG350_RS10905	COG4771	TonB-dependent receptor
EG350_RS10920	COG1960	acyl-CoA dehydrogenase activity
EG350_RS10940	COG0357	Ribosomal RNA small subunit methyltransferase G
EG350_RS10950	COG0436	Aminotransferase
EG350_RS10955	COG0612	Peptidase, M16
EG350_RS10960	COG0450	alkyl hydroperoxide reductase
EG350_RS10990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EG350_RS10995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EG350_RS11000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EG350_RS11065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EG350_RS11080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EG350_RS11080	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EG350_RS11090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EG350_RS11095	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EG350_RS11100	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS11115	COG2205	protein histidine kinase activity
EG350_RS11125	COG0784	Response regulator, receiver
EG350_RS11125	COG4191	Histidine kinase
EG350_RS11140	COG2094	Belongs to the DNA glycosylase MPG family
EG350_RS11160	COG0745	RESPONSE REGULATOR receiver
EG350_RS11170	COG5002	protein histidine kinase activity
EG350_RS11185	COG4221	oxidoreductase activity
EG350_RS11250	COG1233	COG1233 Phytoene dehydrogenase and related
EG350_RS11265	COG1085	galactose-1-phosphate uridylyltransferase
EG350_RS11270	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EG350_RS11285	COG3661	Belongs to the glycosyl hydrolase 67 family
EG350_RS11300	COG2211	Major facilitator Superfamily
EG350_RS11330	COG2160	L-arabinose isomerase activity
EG350_RS11350	COG1472	Belongs to the glycosyl hydrolase 3 family
EG350_RS11365	COG4948	Mandelate Racemase Muconate Lactonizing
EG350_RS11370	COG3507	Belongs to the glycosyl hydrolase 43 family
EG350_RS11380	COG3345	alpha-galactosidase
EG350_RS11385	COG3507	Belongs to the glycosyl hydrolase 43 family
EG350_RS11390	COG3507	Belongs to the glycosyl hydrolase 43 family
EG350_RS11390	COG3693	PFAM glycoside hydrolase, family 10
EG350_RS11390	COG2382	esterase
EG350_RS11395	COG3507	Belongs to the glycosyl hydrolase 43 family
EG350_RS11410	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS11415	COG1312	Catalyzes the dehydration of D-mannonate
EG350_RS11425	COG1629	transport
EG350_RS11430	COG2115	Belongs to the xylose isomerase family
EG350_RS11450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EG350_RS11460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EG350_RS11475	COG0438	transferase activity, transferring glycosyl groups
EG350_RS11495	COG0110	maltose O-acetyltransferase activity
EG350_RS11505	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EG350_RS11510	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EG350_RS11515	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EG350_RS11520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EG350_RS11525	COG3206	protein involved in exopolysaccharide biosynthesis
EG350_RS11525	COG0489	protein tyrosine kinase activity
EG350_RS11535	COG1917	Cupin 2, conserved barrel domain protein
EG350_RS11535	COG2169	Transcriptional regulator
EG350_RS11585	COG0471	metal ion transport
EG350_RS11640	COG0363	glucosamine-6-phosphate deaminase activity
EG350_RS11645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EG350_RS11650	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EG350_RS11695	COG0589	response to stress
EG350_RS11705	COG3457	Alanine racemase
EG350_RS11765	COG1595	DNA-templated transcription, initiation
EG350_RS11790	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EG350_RS11805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EG350_RS11825	COG0110	maltose O-acetyltransferase activity
EG350_RS11830	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EG350_RS11860	COG2204	response regulator
EG350_RS11865	COG0784	Response regulator, receiver
EG350_RS11865	COG2205	protein histidine kinase activity
EG350_RS11875	COG2204	response regulator
EG350_RS11880	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EG350_RS11885	COG0657	acetylesterase activity
EG350_RS11885	COG2755	lipolytic protein G-D-S-L family
EG350_RS11905	COG1725	Transcriptional regulator
EG350_RS11920	COG1304	FMN binding
EG350_RS11925	COG1070	Carbohydrate kinase
EG350_RS11930	COG4952	isomerase
EG350_RS11935	COG3347	Dehydrogenase
EG350_RS11935	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS11940	COG0702	epimerase
EG350_RS11945	COG4771	TonB-dependent receptor
EG350_RS11955	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EG350_RS11960	COG3401	FG-GAP repeat protein
EG350_RS11975	COG2755	lipolytic protein G-D-S-L family
EG350_RS11980	COG3250	beta-galactosidase activity
EG350_RS12030	COG5002	protein histidine kinase activity
EG350_RS12045	COG0492	ferredoxin-NADP+ reductase activity
EG350_RS12070	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EG350_RS12070	COG0662	Cupin 2, conserved barrel domain protein
EG350_RS12100	COG0540	Belongs to the ATCase OTCase family
EG350_RS12105	COG1522	sequence-specific DNA binding
EG350_RS12110	COG0165	Argininosuccinate lyase
EG350_RS12115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EG350_RS12120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EG350_RS12130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EG350_RS12135	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EG350_RS12175	COG5002	protein histidine kinase activity
EG350_RS12180	COG0745	RESPONSE REGULATOR receiver
EG350_RS12190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EG350_RS12200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EG350_RS12205	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EG350_RS12210	COG1295	ribonuclease BN
EG350_RS12220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EG350_RS12230	COG0671	phosphoesterase, PA-phosphatase related
EG350_RS12235	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EG350_RS12245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EG350_RS12245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EG350_RS12260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EG350_RS12270	COG0531	amino acid
EG350_RS12285	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EG350_RS12290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EG350_RS12305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EG350_RS12345	COG1979	alcohol dehydrogenase
EG350_RS12365	COG0513	Belongs to the DEAD box helicase family
EG350_RS12370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EG350_RS12385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EG350_RS12385	COG3153	acetyltransferase
EG350_RS12390	COG0519	Catalyzes the synthesis of GMP from XMP
EG350_RS12390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EG350_RS12395	COG0151	Belongs to the GarS family
EG350_RS12405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EG350_RS12410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EG350_RS12420	COG1741	Belongs to the pirin family
EG350_RS12435	COG0366	Alpha amylase catalytic
EG350_RS12440	COG1082	Xylose isomerase domain protein TIM barrel
EG350_RS12450	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EG350_RS12455	COG1629	transport
EG350_RS12455	COG4206	TonB-dependent receptor
EG350_RS12460	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG350_RS12460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG350_RS12475	COG1566	PFAM secretion protein HlyD family protein
EG350_RS12505	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EG350_RS12515	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EG350_RS12525	COG0077	Prephenate dehydratase
EG350_RS12540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EG350_RS12545	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EG350_RS12550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EG350_RS12555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EG350_RS12555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EG350_RS12560	COG1970	mechanosensitive ion channel activity
EG350_RS12565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EG350_RS12575	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EG350_RS12585	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EG350_RS12595	COG1607	acyl-coa hydrolase
EG350_RS12605	COG0038	chloride channel
EG350_RS12615	COG0477	Major facilitator Superfamily
EG350_RS12620	COG1418	mRNA catabolic process
EG350_RS12640	COG2226	methyltransferase
EG350_RS12650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EG350_RS12655	COG1408	metallophosphoesterase
EG350_RS12665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EG350_RS12675	COG0405	Gamma-glutamyltransferase
EG350_RS12680	COG1301	dicarboxylic acid transport
EG350_RS12710	COG0187	DNA topoisomerase II activity
EG350_RS12715	COG1271	oxidase subunit
EG350_RS12735	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EG350_RS12750	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EG350_RS12760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EG350_RS12765	COG0134	indole-3-glycerol-phosphate synthase activity
EG350_RS12770	COG0135	phosphoribosylanthranilate isomerase activity
EG350_RS12780	COG0133	tryptophan synthase activity
EG350_RS12785	COG0159	tryptophan synthase activity
EG350_RS12790	COG0321	lipoyl(octanoyl) transferase activity
EG350_RS12795	COG0778	Nitroreductase
EG350_RS12800	COG1846	Transcriptional regulator
EG350_RS12805	COG1764	response to oxidative stress
EG350_RS12815	COG0242	peptide deformylase activity
EG350_RS12825	COG3720	iron ion transport
EG350_RS12830	COG2226	methyltransferase
EG350_RS12835	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EG350_RS12840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EG350_RS12875	COG0730	response to heat
EG350_RS12885	COG0175	sulfate reduction
EG350_RS12890	COG0175	sulfate reduction
EG350_RS12895	COG1959	2 iron, 2 sulfur cluster binding
EG350_RS12915	COG0300	oxidoreductase activity
EG350_RS12920	COG0300	oxidoreductase activity
EG350_RS12930	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EG350_RS12940	COG2814	Major facilitator Superfamily
EG350_RS12945	COG0667	Aldo Keto reductase
EG350_RS12950	COG2207	Transcriptional regulator
EG350_RS12950	COG0662	Cupin 2, conserved barrel domain protein
EG350_RS12980	COG1595	DNA-templated transcription, initiation
EG350_RS12985	COG2267	carboxylic ester hydrolase activity
EG350_RS12990	COG1012	belongs to the aldehyde dehydrogenase family
EG350_RS13010	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EG350_RS13030	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EG350_RS13035	COG2852	Protein conserved in bacteria
EG350_RS13050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EG350_RS13060	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EG350_RS13080	COG0539	negative regulation of cytoplasmic translation
EG350_RS13080	COG2183	response to ionizing radiation
EG350_RS13085	COG0513	Belongs to the DEAD box helicase family
EG350_RS13110	COG1187	pseudouridine synthase activity
EG350_RS13120	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EG350_RS13125	COG1968	undecaprenyl-diphosphatase activity
EG350_RS13135	COG2177	Part of the ABC transporter FtsEX involved in
EG350_RS13140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EG350_RS13145	COG0116	Belongs to the methyltransferase superfamily
EG350_RS13170	COG0442	prolyl-tRNA aminoacylation
EG350_RS13180	COG1914	H( )-stimulated, divalent metal cation uptake system
EG350_RS13185	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EG350_RS13190	COG0484	heat shock protein binding
EG350_RS13195	COG2354	Protein conserved in bacteria
EG350_RS13205	COG0586	Pfam SNARE associated Golgi protein
EG350_RS13210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EG350_RS13215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EG350_RS13240	COG3059	membrane
EG350_RS13245	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EG350_RS13270	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EG350_RS13290	COG0149	triose-phosphate isomerase activity
EG350_RS13295	COG0693	protein deglycase activity
EG350_RS13305	COG0358	DNA primase activity
EG350_RS13315	COG0802	atpase or kinase
EG350_RS13335	COG3279	Response regulator of the LytR AlgR family
EG350_RS13340	COG0475	glutathione-regulated potassium exporter activity
EG350_RS13355	COG1760	l-serine dehydratase
EG350_RS13360	COG0004	ammonium transporteR
EG350_RS13380	COG0837	glucose binding
EG350_RS13420	COG3541	Predicted nucleotidyltransferase
EG350_RS13455	COG1234	tRNA 3'-trailer cleavage
EG350_RS13460	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EG350_RS13470	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EG350_RS13480	COG1960	acyl-CoA dehydrogenase activity
EG350_RS13485	COG1022	Amp-dependent synthetase and ligase
EG350_RS13505	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EG350_RS13510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EG350_RS13535	COG0587	DNA-directed DNA polymerase activity
EG350_RS13540	COG0022	dehydrogenase e1 component
EG350_RS13545	COG3781	membrane
EG350_RS13550	COG1522	sequence-specific DNA binding
EG350_RS13555	COG0626	cystathionine gamma-synthase activity
EG350_RS13575	COG1185	polyribonucleotide nucleotidyltransferase activity
EG350_RS13580	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EG350_RS13590	COG2239	Acts as a magnesium transporter
EG350_RS13610	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EG350_RS13610	COG0321	lipoyl(octanoyl) transferase activity
EG350_RS13770	COG2207	Transcriptional regulator
EG350_RS13770	COG3708	Transcriptional regulator
EG350_RS13790	COG1278	Cold shock
EG350_RS13795	COG0513	Belongs to the DEAD box helicase family
EG350_RS13820	COG1247	-acetyltransferase
EG350_RS13825	COG0798	PFAM Bile acid sodium symporter
EG350_RS13895	COG2197	response regulator
EG350_RS13930	COG2274	protein secretion by the type I secretion system
EG350_RS13935	COG2274	protein secretion by the type I secretion system
EG350_RS13965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG350_RS13990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EG350_RS14005	COG0415	Belongs to the DNA photolyase family
EG350_RS14025	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EG350_RS14045	COG2267	carboxylic ester hydrolase activity
EG350_RS14055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EG350_RS14060	COG0351	phosphomethylpyrimidine kinase
EG350_RS14075	COG1022	Amp-dependent synthetase and ligase
EG350_RS14130	COG2267	carboxylic ester hydrolase activity
EG350_RS14135	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EG350_RS14140	COG0668	transmembrane transport
EG350_RS14160	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EG350_RS14170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EG350_RS14180	COG1193	negative regulation of DNA recombination
EG350_RS14190	COG1131	(ABC) transporter
EG350_RS14200	COG1607	acyl-coa hydrolase
EG350_RS14250	COG1169	isochorismate synthase
EG350_RS14260	COG2095	MarC family integral membrane protein
EG350_RS14275	COG2304	oxidoreductase activity
EG350_RS14280	COG2304	oxidoreductase activity
EG350_RS14300	COG0714	Associated with various cellular activities
EG350_RS14315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EG350_RS14350	COG0492	ferredoxin-NADP+ reductase activity
EG350_RS14365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EG350_RS14370	COG4948	Mandelate Racemase Muconate Lactonizing
EG350_RS14375	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EG350_RS14380	COG0527	aspartate kinase activity
EG350_RS14440	COG3876	Protein conserved in bacteria
EG350_RS14465	COG0484	heat shock protein binding
EG350_RS14470	COG1301	dicarboxylic acid transport
EG350_RS14485	COG1012	belongs to the aldehyde dehydrogenase family
EG350_RS14495	COG3425	synthase
EG350_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS14550	COG5002	protein histidine kinase activity
EG350_RS14555	COG0745	RESPONSE REGULATOR receiver
EG350_RS14575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EG350_RS14585	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EG350_RS14605	COG2356	endonuclease I
EG350_RS14620	COG1902	pentaerythritol trinitrate reductase activity
EG350_RS14640	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EG350_RS14640	COG0617	tRNA 3'-terminal CCA addition
EG350_RS14640	COG0517	IMP dehydrogenase activity
EG350_RS14645	COG0009	L-threonylcarbamoyladenylate synthase
EG350_RS14650	COG2827	Endonuclease containing a URI domain
EG350_RS14670	COG0626	cystathionine gamma-synthase activity
EG350_RS14695	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EG350_RS14720	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
EG350_RS14745	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EG350_RS14750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EG350_RS14775	COG4251	negative regulation of phosphorylation
EG350_RS14805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EG350_RS14835	COG0443	Heat shock 70 kDa protein
EG350_RS14850	COG0248	Ppx GppA phosphatase
EG350_RS14870	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EG350_RS14875	COG0489	protein tyrosine kinase activity
EG350_RS14880	COG3537	Alpha-1,2-mannosidase
EG350_RS14895	COG1301	dicarboxylic acid transport
EG350_RS14930	COG0010	Belongs to the arginase family
EG350_RS14935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EG350_RS14960	COG2378	regulation of single-species biofilm formation
EG350_RS14965	COG1132	(ABC) transporter
EG350_RS14975	COG1137	ATPase activity
EG350_RS14980	COG0113	porphobilinogen synthase activity
EG350_RS14990	COG4152	abc transporter atp-binding protein
EG350_RS14995	COG1668	transmembrane transport
EG350_RS15005	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EG350_RS15015	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EG350_RS15030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EG350_RS15030	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EG350_RS15035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EG350_RS15040	COG1078	dGTPase activity
EG350_RS15050	COG0708	Exodeoxyribonuclease III
EG350_RS15055	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EG350_RS15060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EG350_RS15075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EG350_RS15080	COG0297	glycogen (starch) synthase activity
EG350_RS15105	COG1086	Polysaccharide biosynthesis protein
EG350_RS15125	COG2244	polysaccharide biosynthetic process
EG350_RS15130	COG3206	protein involved in exopolysaccharide biosynthesis
EG350_RS15130	COG0489	protein tyrosine kinase activity
EG350_RS15145	COG2137	regulation of response to DNA damage stimulus
EG350_RS15150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EG350_RS15170	COG0577	efflux transmembrane transporter activity
EG350_RS15170	COG1136	(ABC) transporter
EG350_RS15175	COG1136	(ABC) transporter
EG350_RS15205	COG1418	mRNA catabolic process
EG350_RS15215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EG350_RS15225	COG2827	Endonuclease containing a URI domain
EG350_RS15230	COG0525	valine-tRNA ligase activity
EG350_RS15240	COG2326	polyphosphate kinase activity
EG350_RS15275	COG0017	Asparaginyl-tRNA synthetase
EG350_RS15295	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EG350_RS15300	COG0228	four-way junction DNA binding
EG350_RS15320	COG0339	signal peptide processing
EG350_RS15335	COG2310	stress, protein
EG350_RS15345	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EG350_RS15355	COG0259	pyridoxamine-phosphate oxidase activity
EG350_RS15360	COG1678	Uncharacterized ACR, COG1678
EG350_RS15375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EG350_RS15390	COG3158	transport of potassium into the cell
EG350_RS15395	COG0022	dehydrogenase e1 component
EG350_RS15395	COG0508	dehydrogenase complex catalyzes the overall conversion of
EG350_RS15410	COG1183	phosphatidylcholine synthase activity
EG350_RS15470	COG0612	Peptidase, M16
EG350_RS15480	COG0544	peptidyl-prolyl cis-trans isomerase activity
EG350_RS15500	COG0488	(ABC) transporter
EG350_RS15515	COG4585	Histidine kinase
EG350_RS15535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EG350_RS15550	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EG350_RS15555	COG0720	synthase
EG350_RS15565	COG1040	competence protein
EG350_RS15575	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EG350_RS15580	COG1160	GTP binding
EG350_RS15595	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EG350_RS15620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EG350_RS15640	COG0436	Aminotransferase
EG350_RS15645	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EG350_RS15660	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EG350_RS15665	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EG350_RS15670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EG350_RS15680	COG0552	protein localization to endoplasmic reticulum
EG350_RS15685	COG2261	transglycosylase associated protein
EG350_RS15690	COG0616	signal peptide processing
EG350_RS15715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EG350_RS15720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EG350_RS15720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EG350_RS15725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EG350_RS15750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EG350_RS15760	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EG350_RS15770	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EG350_RS15790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG350_RS15810	COG0656	L-ascorbic acid biosynthetic process
EG350_RS15815	COG0667	Aldo Keto reductase
EG350_RS15835	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS15840	COG1309	transcriptional regulator
EG350_RS15970	COG2211	Major facilitator Superfamily
EG350_RS15985	COG4771	TonB-dependent receptor
EG350_RS16220	COG0629	single-stranded DNA binding
EG350_RS16245	COG0346	lactoylglutathione lyase activity
EG350_RS16250	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EG350_RS16265	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EG350_RS16275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EG350_RS16275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EG350_RS16280	COG1739	Uncharacterized protein family UPF0029
EG350_RS16300	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EG350_RS16305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EG350_RS16310	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EG350_RS16315	COG0649	NAD binding
EG350_RS16320	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EG350_RS16325	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EG350_RS16335	COG1034	ATP synthesis coupled electron transport
EG350_RS16340	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EG350_RS16345	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EG350_RS16350	COG0839	Belongs to the complex I subunit 6 family
EG350_RS16360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EG350_RS16365	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EG350_RS16370	COG1007	ATP synthesis coupled electron transport
EG350_RS16395	COG1289	transmembrane transporter activity
EG350_RS16400	COG3956	TIGRFAM MazG family protein
EG350_RS16425	COG0242	peptide deformylase activity
EG350_RS16430	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EG350_RS16440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EG350_RS16460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EG350_RS16470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EG350_RS16480	COG0564	pseudouridine synthase activity
EG350_RS16490	COG1181	Belongs to the D-alanine--D-alanine ligase family
EG350_RS16495	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EG350_RS16510	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EG350_RS16515	COG1704	LemA family
EG350_RS16545	COG0339	signal peptide processing
EG350_RS16555	COG1047	Peptidyl-prolyl cis-trans
EG350_RS16560	COG4628	conserved protein (DUF2132)
EG350_RS16570	COG0420	3'-5' exonuclease activity
EG350_RS16575	COG0419	ATPase involved in DNA repair
EG350_RS16595	COG0823	Involved in the tonB-independent uptake of proteins
EG350_RS16595	COG1506	peptidase
EG350_RS16600	COG2353	YceI-like domain
EG350_RS16605	COG3384	dioxygenase
EG350_RS16615	COG1404	Belongs to the peptidase S8 family
EG350_RS16625	COG2986	histidine ammonia-lyase
EG350_RS16640	COG0322	excinuclease ABC activity
EG350_RS16665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EG350_RS16735	COG0509	glycine decarboxylation via glycine cleavage system
EG350_RS16745	COG0632	four-way junction helicase activity
EG350_RS16750	COG0280	phosphate acetyltransferase
EG350_RS16750	COG0281	malic enzyme
EG350_RS16785	COG1770	oligopeptidase
EG350_RS16795	COG2207	Transcriptional regulator
EG350_RS16880	COG0551	DNA topoisomerase type I activity
EG350_RS16880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EG350_RS16890	COG0798	PFAM Bile acid sodium symporter
EG350_RS16915	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EG350_RS16925	COG2132	Multicopper oxidase
EG350_RS16950	COG2217	Heavy metal translocating P-type atpase
EG350_RS16980	COG2217	Heavy metal translocating P-type atpase
EG350_RS16995	COG2217	Heavy metal translocating P-type atpase
EG350_RS17010	COG0735	belongs to the Fur family
EG350_RS17065	COG0210	DNA helicase
EG350_RS17215	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EG350_RS17225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EG350_RS17235	COG1490	D-aminoacyl-tRNA deacylase activity
EG350_RS17275	COG1408	metallophosphoesterase
EG350_RS17320	COG2030	dehydratase
EG350_RS17320	COG1012	belongs to the aldehyde dehydrogenase family
EG350_RS17335	COG0183	Belongs to the thiolase family
EG350_RS17355	COG1250	3-hydroxyacyl-CoA dehydrogenase
EG350_RS17360	COG1024	Enoyl-CoA hydratase
EG350_RS17365	COG2151	metal-sulfur cluster biosynthetic enzyme
EG350_RS17375	COG3460	Phenylacetate-CoA oxygenase
EG350_RS17380	COG3396	Phenylacetate-CoA oxygenase
EG350_RS17385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EG350_RS17390	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EG350_RS17410	COG4585	Histidine kinase
EG350_RS17425	COG0542	response to heat
EG350_RS17430	COG0438	transferase activity, transferring glycosyl groups
EG350_RS17440	COG1472	Belongs to the glycosyl hydrolase 3 family
EG350_RS17465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EG350_RS17480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EG350_RS17490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EG350_RS17495	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EG350_RS17500	COG1733	regulation of RNA biosynthetic process
EG350_RS17510	COG0667	Aldo Keto reductase
EG350_RS17515	COG3537	Alpha-1,2-mannosidase
EG350_RS17535	COG1028	Short-chain dehydrogenase reductase Sdr
EG350_RS17545	COG1309	transcriptional regulator
EG350_RS17625	COG1074	ATP-dependent DNA helicase activity
EG350_RS17635	COG1528	Iron-storage protein
EG350_RS17650	COG1640	4-alpha-glucanotransferase
EG350_RS17660	COG0215	cysteine-tRNA ligase activity
EG350_RS17665	COG0302	gtp cyclohydrolase
EG350_RS17675	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EG350_RS17680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EG350_RS17685	COG1410	methionine synthase
EG350_RS17685	COG0646	methionine synthase
EG350_RS17695	COG1410	methionine synthase
EG350_RS17695	COG0646	methionine synthase
EG350_RS17730	COG0714	Associated with various cellular activities
EG350_RS17775	COG0217	transcriptional regulatory protein
EG350_RS17780	COG2885	chlorophyll binding
EG350_RS17785	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EG350_RS17790	COG0488	(ABC) transporter
EG350_RS17795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EG350_RS17795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EG350_RS17800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EG350_RS17860	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EG350_RS17875	COG1834	amidinotransferase
EG350_RS17885	COG0148	phosphopyruvate hydratase activity
EG350_RS17910	COG2197	response regulator
EG350_RS17920	COG0203	ribosomal protein L17
EG350_RS17925	COG0202	RNA polymerase activity
EG350_RS17930	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EG350_RS17935	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EG350_RS17940	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EG350_RS17945	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EG350_RS17950	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EG350_RS17960	COG0200	Binds to the 23S rRNA
EG350_RS17965	COG1841	ribosomal large subunit assembly
EG350_RS17970	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EG350_RS17975	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EG350_RS17980	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EG350_RS17985	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EG350_RS17990	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EG350_RS17995	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EG350_RS18005	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EG350_RS18010	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EG350_RS18015	COG0255	Belongs to the universal ribosomal protein uL29 family
EG350_RS18020	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EG350_RS18025	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EG350_RS18030	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EG350_RS18035	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EG350_RS18040	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EG350_RS18045	COG0089	rRNA binding
EG350_RS18050	COG0088	Forms part of the polypeptide exit tunnel
EG350_RS18055	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EG350_RS18085	COG0051	transcription antitermination factor activity, RNA binding
EG350_RS18090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EG350_RS18095	COG0049	tRNA binding
EG350_RS18100	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EG350_RS18110	COG0783	Belongs to the Dps family
EG350_RS18115	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EG350_RS18135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EG350_RS18155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EG350_RS18160	COG1054	Belongs to the UPF0176 family
EG350_RS18165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EG350_RS18175	COG0251	oxidation-reduction process
EG350_RS18200	COG0268	Binds directly to 16S ribosomal RNA
EG350_RS18215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EG350_RS18220	COG1999	signal sequence binding
EG350_RS18235	COG2217	Heavy metal translocating P-type atpase
EG350_RS18245	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EG350_RS18250	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EG350_RS18265	COG0791	NLP P60 protein
EG350_RS18265	COG1388	LysM domain
EG350_RS18270	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EG350_RS18290	COG1629	transport
EG350_RS18310	COG4771	TonB-dependent receptor
EG350_RS18320	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EG350_RS18325	COG0195	Participates in both transcription termination and antitermination
EG350_RS18330	COG0779	Required for maturation of 30S ribosomal subunits
EG350_RS18335	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EG350_RS18380	COG1216	Glycosyl transferase, family 2
EG350_RS18395	COG0463	Glycosyl transferase, family 2
EG350_RS18410	COG0463	Glycosyl transferase, family 2
EG350_RS18430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EG350_RS18445	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EG350_RS18450	COG2194	sulfuric ester hydrolase activity
EG350_RS18455	COG0288	reversible hydration of carbon dioxide
EG350_RS18465	COG0659	secondary active sulfate transmembrane transporter activity
EG350_RS18480	COG0193	aminoacyl-tRNA hydrolase activity
EG350_RS18510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EG350_RS18550	COG0305	Participates in initiation and elongation during chromosome replication
EG350_RS18555	COG0328	RNA-DNA hybrid ribonuclease activity
EG350_RS18570	COG0778	Nitroreductase
EG350_RS18595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EG350_RS18600	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EG350_RS18625	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EG350_RS18630	COG1611	Belongs to the LOG family
EG350_RS18680	COG1132	(ABC) transporter
EG350_RS18690	COG0688	phosphatidylethanolamine metabolic process
EG350_RS18695	COG0575	Belongs to the CDS family
EG350_RS18705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EG350_RS18710	COG0799	negative regulation of ribosome biogenesis
EG350_RS18715	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EG350_RS18715	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EG350_RS18725	COG0343	queuine tRNA-ribosyltransferase activity
EG350_RS18735	COG0463	Glycosyl transferase, family 2
EG350_RS18750	COG1770	oligopeptidase
EG350_RS18790	COG2207	Transcriptional regulator
EG350_RS18795	COG1764	response to oxidative stress
EG350_RS18805	COG0183	Belongs to the thiolase family
EG350_RS18815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EG350_RS18830	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EG350_RS18835	COG2733	membrane
EG350_RS18840	COG0167	dihydroorotate dehydrogenase activity
EG350_RS18845	COG0564	pseudouridine synthase activity
EG350_RS18855	COG0423	glycine-tRNA ligase activity
EG350_RS18875	COG3620	sequence-specific DNA binding
EG350_RS18880	COG1876	peptidase activity
EG350_RS18885	COG3621	Patatin-like phospholipase
EG350_RS18900	COG0590	tRNA wobble adenosine to inosine editing
EG350_RS18905	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EG350_RS18935	COG0791	NLP P60 protein
EG350_RS18945	COG0772	Belongs to the SEDS family
EG350_RS18950	COG0768	penicillin binding
EG350_RS18970	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EG350_RS18975	COG0181	hydroxymethylbilane synthase activity
EG350_RS18985	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EG350_RS19000	COG0778	Nitroreductase
EG350_RS19005	COG4152	abc transporter atp-binding protein
EG350_RS19015	COG0497	DNA recombination
EG350_RS19050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EG350_RS19055	COG0594	ribonuclease P activity
EG350_RS19075	COG3829	transcription factor binding
EG350_RS19085	COG4804	nuclease activity
EG350_RS19090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EG350_RS19105	COG0028	Belongs to the TPP enzyme family
EG350_RS19115	COG2176	DNA-directed DNA polymerase activity
EG350_RS19120	COG0433	COG0433 Predicted ATPase
EG350_RS19135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EG350_RS19135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG350_RS19145	COG3118	belongs to the thioredoxin family
EG350_RS19185	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EG350_RS19190	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EG350_RS19220	COG3033	Beta-eliminating lyase
EG350_RS19225	COG2133	pyrroloquinoline quinone binding
EG350_RS19230	COG0556	nucleotide-excision repair
EG350_RS19235	COG3530	Putative quorum-sensing-regulated virulence factor
EG350_RS19265	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EG350_RS19300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EG350_RS19310	COG0653	protein targeting
EG350_RS19325	COG1940	carbohydrate kinase activity
EG350_RS19330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EG350_RS19340	COG4206	TonB-dependent receptor
EG350_RS19340	COG1629	transport
EG350_RS19350	COG2153	protein acetylation
EG350_RS19355	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EG350_RS19365	COG2001	Belongs to the MraZ family
EG350_RS19370	COG0275	rRNA processing
EG350_RS19380	COG0768	penicillin binding
EG350_RS19385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EG350_RS19390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EG350_RS19395	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EG350_RS19405	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EG350_RS19415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EG350_RS19435	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EG350_RS19440	COG1610	YqeY-like protein
EG350_RS19470	COG3620	sequence-specific DNA binding
EG350_RS19485	COG0745	RESPONSE REGULATOR receiver
EG350_RS19625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG350_RS19670	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EG350_RS19675	COG0697	spore germination