locus-tag	class	description
EIH08_RS00005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EIH08_RS00025	COG0606	chelatase, subunit chli
EIH08_RS00030	COG0387	Pfam Sodium calcium exchanger
EIH08_RS00045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EIH08_RS00060	COG3591	Belongs to the peptidase S1B family
EIH08_RS00075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EIH08_RS00080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EIH08_RS00100	COG0811	peptide transport
EIH08_RS00105	COG0848	biopolymer transport protein
EIH08_RS00140	COG2166	iron-sulfur cluster assembly
EIH08_RS00155	COG0542	response to heat
EIH08_RS00160	COG0673	inositol 2-dehydrogenase activity
EIH08_RS00175	COG0516	GMP reductase activity
EIH08_RS00405	COG2217	Heavy metal translocating P-type atpase
EIH08_RS00430	COG2132	Multicopper oxidase
EIH08_RS00440	COG2814	Major facilitator Superfamily
EIH08_RS00490	COG0509	glycine decarboxylation via glycine cleavage system
EIH08_RS00495	COG0798	PFAM Bile acid sodium symporter
EIH08_RS00525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EIH08_RS00525	COG0551	DNA topoisomerase type I activity
EIH08_RS00555	COG4221	oxidoreductase activity
EIH08_RS00560	COG1214	PFAM Peptidase M22, glycoprotease
EIH08_RS00570	COG2133	pyrroloquinoline quinone binding
EIH08_RS00590	COG0556	nucleotide-excision repair
EIH08_RS00605	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EIH08_RS00615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EIH08_RS00645	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EIH08_RS00650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EIH08_RS00655	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIH08_RS00660	COG2195	Cleaves the N-terminal amino acid of tripeptides
EIH08_RS00675	COG2151	metal-sulfur cluster biosynthetic enzyme
EIH08_RS00690	COG0719	Fe-S assembly protein
EIH08_RS00695	COG0396	ATPase activity
EIH08_RS00700	COG0719	Fe-S assembly protein
EIH08_RS00720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EIH08_RS00725	COG2321	neutral zinc metallopeptidase
EIH08_RS00730	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EIH08_RS00770	COG0437	4 iron, 4 sulfur cluster binding
EIH08_RS00805	COG1774	PSP1 C-terminal conserved region
EIH08_RS00835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EIH08_RS00860	COG1595	DNA-templated transcription, initiation
EIH08_RS00875	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EIH08_RS00880	COG0181	hydroxymethylbilane synthase activity
EIH08_RS00910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EIH08_RS00940	COG0594	ribonuclease P activity
EIH08_RS00945	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EIH08_RS00955	COG1309	transcriptional regulator
EIH08_RS00980	COG0497	DNA recombination
EIH08_RS00990	COG4152	abc transporter atp-binding protein
EIH08_RS01010	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EIH08_RS01010	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EIH08_RS01020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EIH08_RS01035	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIH08_RS01035	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIH08_RS01055	COG1703	isobutyryl-CoA mutase activity
EIH08_RS01090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EIH08_RS01100	COG0602	queuosine metabolic process
EIH08_RS01105	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EIH08_RS01110	COG0166	Belongs to the GPI family
EIH08_RS01130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EIH08_RS01135	COG2181	nitrate reductase activity
EIH08_RS01135	COG0247	lactate metabolic process
EIH08_RS01145	COG2181	nitrate reductase activity
EIH08_RS01145	COG0247	lactate metabolic process
EIH08_RS01165	COG0367	asparagine synthase
EIH08_RS01170	COG0367	asparagine synthase
EIH08_RS01180	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EIH08_RS01235	COG2217	Heavy metal translocating P-type atpase
EIH08_RS01245	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EIH08_RS01260	COG0564	pseudouridine synthase activity
EIH08_RS01275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EIH08_RS01295	COG1607	acyl-coa hydrolase
EIH08_RS01300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIH08_RS01305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EIH08_RS01320	COG2816	NAD+ diphosphatase activity
EIH08_RS01335	COG1024	Enoyl-CoA hydratase
EIH08_RS01380	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EIH08_RS01385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EIH08_RS01415	COG1216	Glycosyl transferase, family 2
EIH08_RS01415	COG1442	glycosyl transferase family 8
EIH08_RS01425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EIH08_RS01445	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EIH08_RS01510	COG0300	oxidoreductase activity
EIH08_RS01515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EIH08_RS01520	COG1694	Mazg nucleotide pyrophosphohydrolase
EIH08_RS01530	COG0254	rRNA binding
EIH08_RS01550	COG1595	DNA-templated transcription, initiation
EIH08_RS01570	COG0516	GMP reductase activity
EIH08_RS01570	COG0517	IMP dehydrogenase activity
EIH08_RS01585	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EIH08_RS01600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EIH08_RS01630	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EIH08_RS01635	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EIH08_RS01665	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EIH08_RS01680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EIH08_RS01685	COG1215	transferase activity, transferring glycosyl groups
EIH08_RS01695	COG0438	transferase activity, transferring glycosyl groups
EIH08_RS01710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EIH08_RS01715	COG0439	Biotin carboxylase
EIH08_RS01720	COG0511	ligase activity, forming carbon-carbon bonds
EIH08_RS01725	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EIH08_RS01735	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EIH08_RS01740	COG0307	riboflavin synthase, alpha
EIH08_RS01750	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EIH08_RS01755	COG2884	Cell division ATP-binding protein ftsE
EIH08_RS01760	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EIH08_RS01765	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EIH08_RS01770	COG0596	Alpha beta hydrolase
EIH08_RS01790	COG0037	tRNA processing
EIH08_RS01800	COG4122	O-methyltransferase activity
EIH08_RS01805	COG0791	NLP P60 protein
EIH08_RS01810	COG1519	Transferase
EIH08_RS01835	COG0848	biopolymer transport protein
EIH08_RS01865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EIH08_RS01880	COG1132	(ABC) transporter
EIH08_RS01885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EIH08_RS01915	COG0658	competence protein
EIH08_RS01915	COG2333	competence protein COMEC
EIH08_RS01930	COG1404	Belongs to the peptidase S8 family
EIH08_RS01940	COG1053	succinate dehydrogenase
EIH08_RS01950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EIH08_RS01965	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EIH08_RS01995	COG0237	dephospho-CoA kinase activity
EIH08_RS02000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIH08_RS02005	COG2255	four-way junction helicase activity
EIH08_RS02010	COG1228	amidohydrolase
EIH08_RS02035	COG0571	ribonuclease III activity
EIH08_RS02040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EIH08_RS02045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EIH08_RS02050	COG0302	gtp cyclohydrolase
EIH08_RS02055	COG0215	cysteine-tRNA ligase activity
EIH08_RS02060	COG1640	4-alpha-glucanotransferase
EIH08_RS02085	COG1528	Iron-storage protein
EIH08_RS02095	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EIH08_RS02130	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EIH08_RS02160	COG0488	(ABC) transporter
EIH08_RS02165	COG0671	phosphoesterase, PA-phosphatase related
EIH08_RS02170	COG0823	Involved in the tonB-independent uptake of proteins
EIH08_RS02170	COG1506	peptidase
EIH08_RS02210	COG1704	LemA family
EIH08_RS02215	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EIH08_RS02235	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EIH08_RS02240	COG1181	Belongs to the D-alanine--D-alanine ligase family
EIH08_RS02250	COG0564	pseudouridine synthase activity
EIH08_RS02260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EIH08_RS02265	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EIH08_RS02295	COG0101	tRNA pseudouridine synthase activity
EIH08_RS02300	COG1132	(ABC) transporter
EIH08_RS02320	COG0459	protein refolding
EIH08_RS02325	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EIH08_RS02355	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EIH08_RS02360	COG0504	CTP synthase activity
EIH08_RS02365	COG0706	membrane insertase activity
EIH08_RS02375	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EIH08_RS02390	COG0018	arginyl-trna synthetase
EIH08_RS02435	COG0326	Molecular chaperone. Has ATPase activity
EIH08_RS02440	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EIH08_RS02480	COG0205	6-phosphofructokinase activity
EIH08_RS02510	COG4974	Belongs to the 'phage' integrase family
EIH08_RS02515	COG0517	IMP dehydrogenase activity
EIH08_RS02520	COG0612	Peptidase, M16
EIH08_RS02540	COG0589	response to stress
EIH08_RS02555	COG1663	tetraacyldisaccharide 4'-kinase activity
EIH08_RS02565	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EIH08_RS02610	COG2132	Multicopper oxidase
EIH08_RS02635	COG2217	Heavy metal translocating P-type atpase
EIH08_RS02685	COG0438	transferase activity, transferring glycosyl groups
EIH08_RS02690	COG1472	Belongs to the glycosyl hydrolase 3 family
EIH08_RS02700	COG0813	purine-nucleoside phosphorylase activity
EIH08_RS02705	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EIH08_RS02720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EIH08_RS02740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EIH08_RS02745	COG0756	dUTP diphosphatase activity
EIH08_RS02755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EIH08_RS02785	COG1028	Short-chain dehydrogenase reductase Sdr
EIH08_RS02790	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EIH08_RS02805	COG0542	response to heat
EIH08_RS02810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EIH08_RS02820	COG3396	Phenylacetate-CoA oxygenase
EIH08_RS02830	COG3460	Phenylacetate-CoA oxygenase
EIH08_RS02840	COG2151	metal-sulfur cluster biosynthetic enzyme
EIH08_RS02865	COG1943	Transposase
EIH08_RS02980	COG0297	glycogen (starch) synthase activity
EIH08_RS02985	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EIH08_RS02990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EIH08_RS03000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EIH08_RS03050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EIH08_RS03055	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EIH08_RS03060	COG0708	Exodeoxyribonuclease III
EIH08_RS03065	COG0745	RESPONSE REGULATOR receiver
EIH08_RS03070	COG1078	dGTPase activity
EIH08_RS03080	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIH08_RS03085	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EIH08_RS03085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EIH08_RS03095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EIH08_RS03100	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIH08_RS03105	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EIH08_RS03120	COG4152	abc transporter atp-binding protein
EIH08_RS03165	COG0443	Heat shock 70 kDa protein
EIH08_RS03185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EIH08_RS03205	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
EIH08_RS03255	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EIH08_RS03265	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EIH08_RS03280	COG0295	cytidine deaminase activity
EIH08_RS03325	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EIH08_RS03335	COG2732	(Barnase) inhibitor
EIH08_RS03355	COG0745	RESPONSE REGULATOR receiver
EIH08_RS03360	COG5002	protein histidine kinase activity
EIH08_RS03395	COG1301	dicarboxylic acid transport
EIH08_RS03400	COG0484	heat shock protein binding
EIH08_RS03415	COG0492	ferredoxin-NADP+ reductase activity
EIH08_RS03420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EIH08_RS03440	COG1136	(ABC) transporter
EIH08_RS03440	COG0577	efflux transmembrane transporter activity
EIH08_RS03445	COG1136	(ABC) transporter
EIH08_RS03445	COG0577	efflux transmembrane transporter activity
EIH08_RS03515	COG0527	aspartate kinase activity
EIH08_RS03520	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EIH08_RS03525	COG4948	Mandelate Racemase Muconate Lactonizing
EIH08_RS03530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EIH08_RS03535	COG2205	protein histidine kinase activity
EIH08_RS03535	COG0784	Response regulator, receiver
EIH08_RS03545	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EIH08_RS03560	COG5002	protein histidine kinase activity
EIH08_RS03585	COG3876	Protein conserved in bacteria
EIH08_RS03615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIH08_RS03625	COG0714	Associated with various cellular activities
EIH08_RS03660	COG2095	MarC family integral membrane protein
EIH08_RS03670	COG1169	isochorismate synthase
EIH08_RS03705	COG1137	ATPase activity
EIH08_RS03715	COG1193	negative regulation of DNA recombination
EIH08_RS03720	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EIH08_RS03735	COG0668	transmembrane transport
EIH08_RS03740	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EIH08_RS03745	COG0596	Alpha beta hydrolase
EIH08_RS03765	COG1022	Amp-dependent synthetase and ligase
EIH08_RS03775	COG0346	lactoylglutathione lyase activity
EIH08_RS03785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EIH08_RS03790	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EIH08_RS03800	COG0626	cystathionine gamma-synthase activity
EIH08_RS03840	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EIH08_RS03845	COG0783	Belongs to the Dps family
EIH08_RS03855	COG1793	dna ligase
EIH08_RS03855	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EIH08_RS03880	COG1058	Belongs to the CinA family
EIH08_RS03880	COG1546	Belongs to the CinA family
EIH08_RS03890	COG3590	peptidase
EIH08_RS03910	COG4717	serine-type aminopeptidase activity
EIH08_RS03915	COG2217	Heavy metal translocating P-type atpase
EIH08_RS03930	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EIH08_RS03935	COG4771	TonB-dependent receptor
EIH08_RS03945	COG0584	glycerophosphoryl diester phosphodiesterase
EIH08_RS03955	COG0004	ammonium transporteR
EIH08_RS03960	COG0022	dehydrogenase e1 component
EIH08_RS03965	COG0587	DNA-directed DNA polymerase activity
EIH08_RS03995	COG1131	(ABC) transporter
EIH08_RS04010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EIH08_RS04045	COG0463	Glycosyl transferase, family 2
EIH08_RS04045	COG1216	Glycosyl transferase, family 2
EIH08_RS04075	COG0442	prolyl-tRNA aminoacylation
EIH08_RS04095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EIH08_RS04110	COG1858	cytochrome C peroxidase
EIH08_RS04130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIH08_RS04130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIH08_RS04135	COG0183	Belongs to the thiolase family
EIH08_RS04170	COG1428	Deoxynucleoside kinase
EIH08_RS04175	COG1393	Belongs to the ArsC family
EIH08_RS04190	COG4771	TonB-dependent receptor
EIH08_RS04195	COG0702	epimerase
EIH08_RS04225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EIH08_RS04230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EIH08_RS04240	COG0592	DNA-directed DNA polymerase activity
EIH08_RS04260	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIH08_RS04270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EIH08_RS04290	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EIH08_RS04330	COG1028	Short-chain dehydrogenase reductase Sdr
EIH08_RS04345	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EIH08_RS04350	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EIH08_RS04425	COG0484	heat shock protein binding
EIH08_RS04495	COG1649	PFAM Uncharacterised BCR, COG1649
EIH08_RS04500	COG0724	RNA recognition motif
EIH08_RS04505	COG0012	GTP binding
EIH08_RS04525	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EIH08_RS04535	COG1289	transmembrane transporter activity
EIH08_RS04550	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EIH08_RS04565	COG1181	Belongs to the D-alanine--D-alanine ligase family
EIH08_RS04580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EIH08_RS04585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EIH08_RS04595	COG2211	Major facilitator Superfamily
EIH08_RS04600	COG0183	Belongs to the thiolase family
EIH08_RS04605	COG2270	Major facilitator Superfamily
EIH08_RS04630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EIH08_RS04635	COG0671	phosphoesterase, PA-phosphatase related
EIH08_RS04645	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EIH08_RS04650	COG1295	ribonuclease BN
EIH08_RS04655	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EIH08_RS04660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EIH08_RS04665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EIH08_RS04670	COG0540	Belongs to the ATCase OTCase family
EIH08_RS04730	COG2197	response regulator
EIH08_RS04760	COG0402	S-adenosylhomocysteine deaminase activity
EIH08_RS04765	COG1228	amidohydrolase
EIH08_RS04780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIH08_RS04790	COG0640	Transcriptional regulator
EIH08_RS04805	COG0798	PFAM Bile acid sodium symporter
EIH08_RS04840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EIH08_RS04845	COG1764	response to oxidative stress
EIH08_RS04850	COG1846	Transcriptional regulator
EIH08_RS04855	COG0778	Nitroreductase
EIH08_RS04875	COG0573	inorganic phosphate transmembrane transporter activity
EIH08_RS04880	COG0581	inorganic phosphate transmembrane transporter activity
EIH08_RS04885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EIH08_RS04905	COG1538	Outer membrane efflux protein
EIH08_RS04915	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EIH08_RS04925	COG0732	type I restriction modification DNA specificity domain
EIH08_RS04935	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EIH08_RS04950	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EIH08_RS04955	COG0297	glycogen (starch) synthase activity
EIH08_RS04960	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EIH08_RS04975	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIH08_RS04980	COG2967	ApaG domain
EIH08_RS04990	COG1073	alpha beta
EIH08_RS05025	COG1012	belongs to the aldehyde dehydrogenase family
EIH08_RS05030	COG1028	Short-chain dehydrogenase reductase Sdr
EIH08_RS05035	COG0598	Magnesium transport protein CorA
EIH08_RS05040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIH08_RS05055	COG1012	belongs to the aldehyde dehydrogenase family
EIH08_RS05065	COG0667	Aldo Keto reductase
EIH08_RS05070	COG0673	inositol 2-dehydrogenase activity
EIH08_RS05085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EIH08_RS05085	COG0723	plastoquinol--plastocyanin reductase activity
EIH08_RS05090	COG1058	Belongs to the CinA family
EIH08_RS05090	COG1546	Belongs to the CinA family
EIH08_RS05095	COG3685	Protein conserved in bacteria
EIH08_RS05165	COG0006	proline dipeptidase activity
EIH08_RS05170	COG0335	large ribosomal subunit rRNA binding
EIH08_RS05210	COG0531	amino acid
EIH08_RS05225	COG1575	Belongs to the MenA family. Type 1 subfamily
EIH08_RS05230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EIH08_RS05260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EIH08_RS05270	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EIH08_RS05280	COG0386	Belongs to the glutathione peroxidase family
EIH08_RS05285	COG0702	epimerase
EIH08_RS05295	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EIH08_RS05305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EIH08_RS05310	COG0156	8-amino-7-oxononanoate synthase activity
EIH08_RS05335	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EIH08_RS05350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EIH08_RS05350	COG3153	acetyltransferase
EIH08_RS05355	COG0534	Mate efflux family protein
EIH08_RS05375	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EIH08_RS05390	COG0693	protein deglycase activity
EIH08_RS05400	COG3685	Protein conserved in bacteria
EIH08_RS05405	COG2217	Heavy metal translocating P-type atpase
EIH08_RS05415	COG1607	acyl-coa hydrolase
EIH08_RS05495	COG0156	8-amino-7-oxononanoate synthase activity
EIH08_RS05515	COG0175	sulfate reduction
EIH08_RS05520	COG0175	sulfate reduction
EIH08_RS05525	COG1959	2 iron, 2 sulfur cluster binding
EIH08_RS05545	COG1981	membrane
EIH08_RS05555	COG1702	phosphate starvation-inducible protein PhoH
EIH08_RS05585	COG0356	it plays a direct role in the translocation of protons across the membrane
EIH08_RS05595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EIH08_RS05600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EIH08_RS05605	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EIH08_RS05610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EIH08_RS05615	COG1253	flavin adenine dinucleotide binding
EIH08_RS05620	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EIH08_RS05630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIH08_RS05650	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EIH08_RS05660	COG0528	UMP kinase activity
EIH08_RS05665	COG0233	cytoplasmic translational termination
EIH08_RS05680	COG1674	ftsk spoiiie
EIH08_RS05685	COG1333	cytochrome c biogenesis protein
EIH08_RS05685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EIH08_RS05690	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EIH08_RS05690	COG0662	Cupin 2, conserved barrel domain protein
EIH08_RS05695	COG1011	Hydrolase
EIH08_RS05715	COG0492	ferredoxin-NADP+ reductase activity
EIH08_RS05720	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EIH08_RS05745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EIH08_RS05775	COG1960	acyl-CoA dehydrogenase activity
EIH08_RS05795	COG1024	Enoyl-CoA hydratase
EIH08_RS05795	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIH08_RS05805	COG1120	ATPase activity
EIH08_RS05815	COG3118	belongs to the thioredoxin family
EIH08_RS05825	COG2949	membrane
EIH08_RS05830	COG0572	uridine kinase
EIH08_RS05840	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIH08_RS05840	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EIH08_RS05860	COG0300	oxidoreductase activity
EIH08_RS05870	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EIH08_RS05885	COG1506	peptidase
EIH08_RS05895	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EIH08_RS05900	COG2226	methyltransferase
EIH08_RS05920	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EIH08_RS05930	COG0352	thiamine-phosphate diphosphorylase activity
EIH08_RS05940	COG2226	methyltransferase
EIH08_RS05960	COG0562	UDP-galactopyranose mutase
EIH08_RS05970	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EIH08_RS05970	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EIH08_RS05975	COG1472	Belongs to the glycosyl hydrolase 3 family
EIH08_RS05990	COG4124	Belongs to the glycosyl hydrolase 26 family
EIH08_RS05995	COG3345	alpha-galactosidase
EIH08_RS06010	COG2942	2-epimerase
EIH08_RS06015	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EIH08_RS06020	COG2211	Major facilitator Superfamily
EIH08_RS06035	COG2169	Transcriptional regulator
EIH08_RS06040	COG4771	TonB-dependent receptor
EIH08_RS06045	COG0561	phosphatase activity
EIH08_RS06060	COG0519	Catalyzes the synthesis of GMP from XMP
EIH08_RS06075	COG0436	Aminotransferase
EIH08_RS06080	COG0450	alkyl hydroperoxide reductase
EIH08_RS06085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EIH08_RS06100	COG1247	-acetyltransferase
EIH08_RS06105	COG2323	membrane
EIH08_RS06115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EIH08_RS06140	COG1335	isochorismatase
EIH08_RS06150	COG1187	pseudouridine synthase activity
EIH08_RS06170	COG1960	acyl-CoA dehydrogenase activity
EIH08_RS06185	COG1321	iron dependent repressor
EIH08_RS06210	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EIH08_RS06215	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EIH08_RS06220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIH08_RS06235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EIH08_RS06245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EIH08_RS06250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EIH08_RS06250	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EIH08_RS06270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EIH08_RS06280	COG2183	response to ionizing radiation
EIH08_RS06280	COG0539	negative regulation of cytoplasmic translation
EIH08_RS06295	COG1187	pseudouridine synthase activity
EIH08_RS06305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EIH08_RS06320	COG2177	Part of the ABC transporter FtsEX involved in
EIH08_RS06325	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EIH08_RS06330	COG2239	Acts as a magnesium transporter
EIH08_RS06345	COG1234	tRNA 3'-trailer cleavage
EIH08_RS06350	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EIH08_RS06360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EIH08_RS06380	COG1960	acyl-CoA dehydrogenase activity
EIH08_RS06385	COG1022	Amp-dependent synthetase and ligase
EIH08_RS06395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EIH08_RS06415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EIH08_RS06430	COG0022	dehydrogenase e1 component
EIH08_RS06435	COG0142	geranyltranstransferase activity
EIH08_RS06450	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EIH08_RS06460	COG1506	peptidase
EIH08_RS06460	COG0823	Involved in the tonB-independent uptake of proteins
EIH08_RS06475	COG1950	PFAM Membrane protein of
EIH08_RS06535	COG1233	COG1233 Phytoene dehydrogenase and related
EIH08_RS06570	COG2801	Transposase and inactivated derivatives
EIH08_RS06645	COG2217	Heavy metal translocating P-type atpase
EIH08_RS06685	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EIH08_RS06690	COG0732	type I restriction modification DNA specificity domain
EIH08_RS06695	COG3177	Filamentation induced by cAMP protein fic
EIH08_RS06710	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EIH08_RS06740	COG4974	Belongs to the 'phage' integrase family
EIH08_RS06750	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EIH08_RS06755	COG0105	UTP biosynthetic process
EIH08_RS06760	COG1162	GTPase activity
EIH08_RS06765	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EIH08_RS06765	COG1605	Chorismate mutase
EIH08_RS06775	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EIH08_RS06780	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EIH08_RS06785	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EIH08_RS06800	COG2003	Belongs to the UPF0758 family
EIH08_RS06805	COG1136	(ABC) transporter
EIH08_RS06815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EIH08_RS06835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EIH08_RS06840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EIH08_RS06855	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EIH08_RS06860	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EIH08_RS06865	COG0438	transferase activity, transferring glycosyl groups
EIH08_RS06875	COG2171	N-acyltransferase activity
EIH08_RS06880	COG0791	NLP P60 protein
EIH08_RS06890	COG1278	Cold shock
EIH08_RS06900	COG3609	addiction module antidote protein, CC2985 family
EIH08_RS06930	COG3657	addiction module killer protein
EIH08_RS06935	COG4974	Belongs to the 'phage' integrase family
EIH08_RS06940	COG0517	IMP dehydrogenase activity
EIH08_RS06960	COG0531	amino acid
EIH08_RS06975	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EIH08_RS06980	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EIH08_RS06990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EIH08_RS07005	COG1979	alcohol dehydrogenase
EIH08_RS07015	COG0513	Belongs to the DEAD box helicase family
EIH08_RS07025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIH08_RS07030	COG0405	Gamma-glutamyltransferase
EIH08_RS07040	COG0187	DNA topoisomerase II activity
EIH08_RS07045	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EIH08_RS07050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EIH08_RS07055	COG0512	Glutamine amidotransferase of anthranilate synthase
EIH08_RS07060	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EIH08_RS07065	COG0134	indole-3-glycerol-phosphate synthase activity
EIH08_RS07070	COG0135	phosphoribosylanthranilate isomerase activity
EIH08_RS07075	COG0133	tryptophan synthase activity
EIH08_RS07080	COG0159	tryptophan synthase activity
EIH08_RS07085	COG1309	transcriptional regulator
EIH08_RS07090	COG0321	lipoyl(octanoyl) transferase activity
EIH08_RS07095	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIH08_RS07110	COG0360	Binds together with S18 to 16S ribosomal RNA
EIH08_RS07115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EIH08_RS07120	COG0359	binds to the 23S rRNA
EIH08_RS07155	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EIH08_RS07185	COG0124	histidyl-tRNA synthetase
EIH08_RS07190	COG0456	acetyltransferase
EIH08_RS07200	COG0629	single-stranded DNA binding
EIH08_RS07220	COG2996	Protein conserved in bacteria
EIH08_RS07235	COG0438	transferase activity, transferring glycosyl groups
EIH08_RS07240	COG0514	ATP-dependent DNA helicase (RecQ)
EIH08_RS07245	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EIH08_RS07245	COG0517	IMP dehydrogenase activity
EIH08_RS07250	COG0805	protein transport
EIH08_RS07280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EIH08_RS07285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EIH08_RS07290	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EIH08_RS07295	COG0824	Thioesterase
EIH08_RS07300	COG3340	Belongs to the peptidase S51 family
EIH08_RS07310	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EIH08_RS07315	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EIH08_RS07325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EIH08_RS07330	COG0077	Prephenate dehydratase
EIH08_RS07345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EIH08_RS07385	COG3022	response to hydroperoxide
EIH08_RS07390	COG2890	protein-(glutamine-N5) methyltransferase activity
EIH08_RS07415	COG0519	Catalyzes the synthesis of GMP from XMP
EIH08_RS07415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EIH08_RS07420	COG0151	Belongs to the GarS family
EIH08_RS07440	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EIH08_RS07445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EIH08_RS07450	COG2354	Protein conserved in bacteria
EIH08_RS07460	COG1741	Belongs to the pirin family
EIH08_RS07475	COG0366	Alpha amylase catalytic
EIH08_RS07485	COG1082	Xylose isomerase domain protein TIM barrel
EIH08_RS07500	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EIH08_RS07505	COG4206	TonB-dependent receptor
EIH08_RS07505	COG1629	transport
EIH08_RS07510	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIH08_RS07510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIH08_RS07525	COG1970	mechanosensitive ion channel activity
EIH08_RS07530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIH08_RS07540	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EIH08_RS07545	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EIH08_RS07560	COG1652	LysM domain
EIH08_RS07570	COG1418	mRNA catabolic process
EIH08_RS07590	COG2226	methyltransferase
EIH08_RS07605	COG1408	metallophosphoesterase
EIH08_RS07690	COG0484	heat shock protein binding
EIH08_RS07745	COG0739	heme binding
EIH08_RS07755	COG2003	Belongs to the UPF0758 family
EIH08_RS07765	COG4680	protein conserved in bacteria
EIH08_RS07920	COG3279	Response regulator of the LytR AlgR family
EIH08_RS07925	COG3275	phosphorelay sensor kinase activity
EIH08_RS07960	COG4974	Belongs to the 'phage' integrase family
EIH08_RS07990	COG2204	response regulator
EIH08_RS08020	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EIH08_RS08030	COG2205	protein histidine kinase activity
EIH08_RS08035	COG5002	protein histidine kinase activity
EIH08_RS08135	COG0582	viral genome integration into host DNA
EIH08_RS08180	COG2801	Transposase and inactivated derivatives
EIH08_RS08185	COG4974	Belongs to the 'phage' integrase family
EIH08_RS08200	COG3118	belongs to the thioredoxin family
EIH08_RS08205	COG1104	cysteine desulfurase activity
EIH08_RS08225	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EIH08_RS08250	COG0681	Belongs to the peptidase S26 family
EIH08_RS08255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EIH08_RS08280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EIH08_RS08285	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EIH08_RS08290	COG0563	adenylate kinase activity
EIH08_RS08310	COG0084	hydrolase, TatD family'
EIH08_RS08325	COG0306	phosphate transporter
EIH08_RS08335	COG0513	Belongs to the DEAD box helicase family
EIH08_RS08345	COG0366	Alpha amylase catalytic
EIH08_RS08370	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EIH08_RS08375	COG1442	glycosyl transferase family 8
EIH08_RS08375	COG1216	Glycosyl transferase, family 2
EIH08_RS08385	COG3023	N-Acetylmuramoyl-L-alanine amidase
EIH08_RS08435	COG1476	TRANSCRIPTIONal
EIH08_RS08440	COG2003	Belongs to the UPF0758 family
EIH08_RS08505	COG2264	protein methyltransferase activity
EIH08_RS08510	COG0149	triose-phosphate isomerase activity
EIH08_RS08530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EIH08_RS08545	COG0358	DNA primase activity
EIH08_RS08555	COG3385	transposase activity
EIH08_RS08560	COG2755	lipolytic protein G-D-S-L family
EIH08_RS08560	COG0657	acetylesterase activity
EIH08_RS08565	COG0484	heat shock protein binding
EIH08_RS08570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EIH08_RS08575	COG1914	H( )-stimulated, divalent metal cation uptake system
EIH08_RS08580	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EIH08_RS08585	COG0586	Pfam SNARE associated Golgi protein
EIH08_RS08590	COG1446	asparaginase
EIH08_RS08595	COG0802	atpase or kinase
EIH08_RS08610	COG0287	Prephenate dehydrogenase
EIH08_RS08615	COG1760	l-serine dehydratase
EIH08_RS08630	COG0837	glucose binding
EIH08_RS08640	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EIH08_RS08655	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EIH08_RS08665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EIH08_RS08680	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EIH08_RS08680	COG0321	lipoyl(octanoyl) transferase activity
EIH08_RS08695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EIH08_RS08705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EIH08_RS08720	COG1194	a g-specific adenine glycosylase
EIH08_RS08725	COG0776	regulation of translation
EIH08_RS08760	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EIH08_RS08765	COG0427	acetyl-CoA hydrolase
EIH08_RS08770	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EIH08_RS08795	COG0861	Integral membrane protein TerC family
EIH08_RS08800	COG0612	Peptidase, M16
EIH08_RS08805	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EIH08_RS08805	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EIH08_RS08820	COG0210	DNA helicase
EIH08_RS08835	COG0745	RESPONSE REGULATOR receiver
EIH08_RS08855	COG1216	Glycosyl transferase, family 2
EIH08_RS08860	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EIH08_RS08875	COG2195	Cleaves the N-terminal amino acid of tripeptides
EIH08_RS08890	COG0492	ferredoxin-NADP+ reductase activity
EIH08_RS08905	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EIH08_RS08915	COG3842	ATPase activity
EIH08_RS08920	COG2824	Alkylphosphonate utilization operon protein PhnA
EIH08_RS08930	COG0367	asparagine synthase
EIH08_RS08975	COG1250	3-hydroxyacyl-CoA dehydrogenase
EIH08_RS09050	COG2205	protein histidine kinase activity
EIH08_RS09060	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EIH08_RS09065	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EIH08_RS09105	COG0702	epimerase
EIH08_RS09135	COG0582	viral genome integration into host DNA
EIH08_RS09160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EIH08_RS09170	COG1522	sequence-specific DNA binding
EIH08_RS09190	COG3959	Transketolase, thiamine diphosphate binding domain
EIH08_RS09195	COG4145	pantothenate transmembrane transporter activity
EIH08_RS09200	COG2388	GCN5-related N-acetyl-transferase
EIH08_RS09240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EIH08_RS09250	COG0297	glycogen (starch) synthase activity
EIH08_RS09255	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EIH08_RS09275	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EIH08_RS09295	COG0069	glutamate synthase activity
EIH08_RS09300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EIH08_RS09320	COG1506	peptidase
EIH08_RS09320	COG0823	Involved in the tonB-independent uptake of proteins
EIH08_RS09340	COG3104	oligopeptide transport
EIH08_RS09350	COG4232	protein-disulfide reductase activity
EIH08_RS09375	COG1381	Involved in DNA repair and RecF pathway recombination
EIH08_RS09385	COG0737	Belongs to the 5'-nucleotidase family
EIH08_RS09395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EIH08_RS09415	COG0784	Response regulator, receiver
EIH08_RS09420	COG4251	negative regulation of phosphorylation
EIH08_RS09440	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EIH08_RS09445	COG0739	heme binding
EIH08_RS09460	COG0346	lactoylglutathione lyase activity
EIH08_RS09465	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EIH08_RS09480	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EIH08_RS09485	COG1196	nuclear chromosome segregation
EIH08_RS09490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EIH08_RS09490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EIH08_RS09495	COG1739	Uncharacterized protein family UPF0029
EIH08_RS09520	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIH08_RS09525	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIH08_RS09530	COG0649	NAD binding
EIH08_RS09535	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EIH08_RS09550	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EIH08_RS09555	COG1034	ATP synthesis coupled electron transport
EIH08_RS09560	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EIH08_RS09565	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIH08_RS09570	COG0839	Belongs to the complex I subunit 6 family
EIH08_RS09575	COG0713	ATP synthesis coupled electron transport
EIH08_RS09580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EIH08_RS09585	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EIH08_RS09590	COG1007	ATP synthesis coupled electron transport
EIH08_RS09600	COG3956	TIGRFAM MazG family protein
EIH08_RS09610	COG0242	peptide deformylase activity
EIH08_RS09615	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EIH08_RS09620	COG0045	succinate-CoA ligase (ADP-forming) activity
EIH08_RS09635	COG2363	Small membrane protein
EIH08_RS09655	COG2353	YceI-like domain
EIH08_RS09675	COG2986	histidine ammonia-lyase
EIH08_RS09700	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EIH08_RS09720	COG0336	Belongs to the RNA methyltransferase TrmD family
EIH08_RS09735	COG0488	(ABC) transporter
EIH08_RS09740	COG0531	amino acid
EIH08_RS09745	COG4774	siderophore transport
EIH08_RS09765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EIH08_RS09770	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EIH08_RS09770	COG0284	orotidine-5'-phosphate decarboxylase activity
EIH08_RS09785	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EIH08_RS09790	COG0248	Ppx GppA phosphatase
EIH08_RS09795	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EIH08_RS09800	COG0489	protein tyrosine kinase activity
EIH08_RS09805	COG1301	dicarboxylic acid transport
EIH08_RS09825	COG0010	Belongs to the arginase family
EIH08_RS09840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EIH08_RS09855	COG2096	Adenosyltransferase
EIH08_RS09865	COG2226	methyltransferase
EIH08_RS09875	COG1132	(ABC) transporter
EIH08_RS09880	COG2989	Protein conserved in bacteria
EIH08_RS09885	COG1137	ATPase activity
EIH08_RS09895	COG0113	porphobilinogen synthase activity
EIH08_RS09905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EIH08_RS09945	COG0509	glycine decarboxylation via glycine cleavage system
EIH08_RS09960	COG0280	phosphate acetyltransferase
EIH08_RS09960	COG0281	malic enzyme
EIH08_RS10025	COG0537	adenosine 5'-monophosphoramidase activity
EIH08_RS10030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EIH08_RS10040	COG1490	D-aminoacyl-tRNA deacylase activity
EIH08_RS10085	COG2137	regulation of response to DNA damage stimulus
EIH08_RS10090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EIH08_RS10115	COG1136	(ABC) transporter
EIH08_RS10120	COG1136	(ABC) transporter
EIH08_RS10120	COG0577	efflux transmembrane transporter activity
EIH08_RS10125	COG0577	efflux transmembrane transporter activity
EIH08_RS10125	COG1136	(ABC) transporter
EIH08_RS10140	COG1418	mRNA catabolic process
EIH08_RS10150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIH08_RS10160	COG0525	valine-tRNA ligase activity
EIH08_RS10170	COG2326	polyphosphate kinase activity
EIH08_RS10180	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EIH08_RS10185	COG0228	four-way junction DNA binding
EIH08_RS10205	COG0339	signal peptide processing
EIH08_RS10215	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EIH08_RS10225	COG0259	pyridoxamine-phosphate oxidase activity
EIH08_RS10230	COG1678	Uncharacterized ACR, COG1678
EIH08_RS10245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EIH08_RS10260	COG3158	transport of potassium into the cell
EIH08_RS10265	COG0022	dehydrogenase e1 component
EIH08_RS10265	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIH08_RS10280	COG0463	Glycosyl transferase, family 2
EIH08_RS10290	COG1183	phosphatidylcholine synthase activity
EIH08_RS10300	COG0179	Fumarylacetoacetate (FAA) hydrolase
EIH08_RS10310	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EIH08_RS10315	COG0085	RNA polymerase activity
EIH08_RS10345	COG0222	ribosome binding
EIH08_RS10350	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EIH08_RS10355	COG0081	regulation of translation
EIH08_RS10360	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EIH08_RS10375	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIH08_RS10380	COG0720	synthase
EIH08_RS10385	COG2224	Isocitrate lyase
EIH08_RS10400	COG1040	competence protein
EIH08_RS10405	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EIH08_RS10415	COG1160	GTP binding
EIH08_RS10435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EIH08_RS10445	COG0436	Aminotransferase
EIH08_RS10450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EIH08_RS10455	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EIH08_RS10460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EIH08_RS10465	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EIH08_RS10475	COG0552	protein localization to endoplasmic reticulum
EIH08_RS10480	COG2261	transglycosylase associated protein
EIH08_RS10485	COG0616	signal peptide processing
EIH08_RS10505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EIH08_RS10530	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EIH08_RS10540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EIH08_RS10550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EIH08_RS10560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIH08_RS10570	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EIH08_RS10580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EIH08_RS10605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EIH08_RS10610	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EIH08_RS10615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EIH08_RS10620	COG0194	GDP metabolic process
EIH08_RS10625	COG1561	YicC-like family, N-terminal region
EIH08_RS10640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EIH08_RS10660	COG0646	methionine synthase
EIH08_RS10660	COG1410	methionine synthase
EIH08_RS10670	COG0460	homoserine dehydrogenase
EIH08_RS10670	COG0527	aspartate kinase activity
EIH08_RS10700	COG0217	transcriptional regulatory protein
EIH08_RS10710	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EIH08_RS10715	COG0488	(ABC) transporter
EIH08_RS10720	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EIH08_RS10720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EIH08_RS10725	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EIH08_RS10760	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EIH08_RS10775	COG0148	phosphopyruvate hydratase activity
EIH08_RS10785	COG0203	ribosomal protein L17
EIH08_RS10795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EIH08_RS10800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EIH08_RS10805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EIH08_RS10815	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EIH08_RS10825	COG0200	Binds to the 23S rRNA
EIH08_RS10830	COG1841	ribosomal large subunit assembly
EIH08_RS10835	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EIH08_RS10840	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EIH08_RS10845	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EIH08_RS10850	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EIH08_RS10855	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EIH08_RS10870	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EIH08_RS10875	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EIH08_RS10880	COG0255	Belongs to the universal ribosomal protein uL29 family
EIH08_RS10885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EIH08_RS10890	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EIH08_RS10895	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EIH08_RS10900	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EIH08_RS10905	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EIH08_RS10910	COG0089	rRNA binding
EIH08_RS10915	COG0088	Forms part of the polypeptide exit tunnel
EIH08_RS10920	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EIH08_RS10995	COG0051	transcription antitermination factor activity, RNA binding
EIH08_RS11000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EIH08_RS11005	COG0049	tRNA binding
EIH08_RS11010	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EIH08_RS11015	COG0783	Belongs to the Dps family
EIH08_RS11020	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EIH08_RS11035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIH08_RS11075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EIH08_RS11085	COG0251	oxidation-reduction process
EIH08_RS11095	COG0860	N-Acetylmuramoyl-L-alanine amidase
EIH08_RS11105	COG0268	Binds directly to 16S ribosomal RNA
EIH08_RS11115	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EIH08_RS11120	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EIH08_RS11135	COG1705	Flagellar rod assembly protein muramidase FlgJ
EIH08_RS11135	COG1388	LysM domain
EIH08_RS11140	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EIH08_RS11160	COG4771	TonB-dependent receptor
EIH08_RS11165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EIH08_RS11170	COG0195	Participates in both transcription termination and antitermination
EIH08_RS11175	COG0779	Required for maturation of 30S ribosomal subunits
EIH08_RS11185	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EIH08_RS11210	COG1216	Glycosyl transferase, family 2
EIH08_RS11225	COG1216	Glycosyl transferase, family 2
EIH08_RS11235	COG0463	Glycosyl transferase, family 2
EIH08_RS11245	COG0367	asparagine synthase
EIH08_RS11250	COG1216	Glycosyl transferase, family 2
EIH08_RS11265	COG1442	glycosyl transferase family 8
EIH08_RS11280	COG0463	Glycosyl transferase, family 2
EIH08_RS11295	COG3394	polysaccharide catabolic process
EIH08_RS11305	COG0463	Glycosyl transferase, family 2
EIH08_RS11315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EIH08_RS11325	COG1216	Glycosyl transferase, family 2
EIH08_RS11325	COG0463	Glycosyl transferase, family 2
EIH08_RS11345	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EIH08_RS11350	COG0288	reversible hydration of carbon dioxide
EIH08_RS11370	COG0193	aminoacyl-tRNA hydrolase activity
EIH08_RS11390	COG2076	Multidrug Resistance protein
EIH08_RS11400	COG0305	Participates in initiation and elongation during chromosome replication
EIH08_RS11410	COG0778	Nitroreductase
EIH08_RS11435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EIH08_RS11440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EIH08_RS11465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EIH08_RS11485	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EIH08_RS11495	COG0527	aspartate kinase activity
EIH08_RS11525	COG0791	NLP P60 protein
EIH08_RS11550	COG2733	membrane
EIH08_RS11555	COG0167	dihydroorotate dehydrogenase activity
EIH08_RS11565	COG0423	glycine-tRNA ligase activity
EIH08_RS11600	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EIH08_RS11625	COG4106	trans-aconitate 2-methyltransferase activity
EIH08_RS11645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EIH08_RS11655	COG0019	diaminopimelate decarboxylase activity
EIH08_RS11660	COG2176	DNA-directed DNA polymerase activity
EIH08_RS11665	COG0433	COG0433 Predicted ATPase
EIH08_RS11675	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EIH08_RS11700	COG3033	Beta-eliminating lyase
EIH08_RS11710	COG0424	maF-like protein
EIH08_RS11715	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EIH08_RS11755	COG0688	phosphatidylethanolamine metabolic process
EIH08_RS11760	COG4589	Belongs to the CDS family
EIH08_RS11775	COG0799	negative regulation of ribosome biogenesis
EIH08_RS11790	COG0343	queuine tRNA-ribosyltransferase activity
EIH08_RS11800	COG1216	Glycosyl transferase, family 2
EIH08_RS11815	COG1770	oligopeptidase
EIH08_RS11835	COG0772	Belongs to the SEDS family
EIH08_RS11860	COG0481	GTPase activity
EIH08_RS11870	COG1538	Outer membrane efflux protein
EIH08_RS11890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EIH08_RS11895	COG0700	Nucleoside recognition
EIH08_RS11910	COG1610	YqeY-like protein
EIH08_RS11930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EIH08_RS11935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EIH08_RS11940	COG0772	Belongs to the SEDS family
EIH08_RS11945	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EIH08_RS11950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EIH08_RS11955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EIH08_RS11970	COG0275	rRNA processing
EIH08_RS11985	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EIH08_RS11990	COG2153	protein acetylation
EIH08_RS12005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EIH08_RS12010	COG1940	carbohydrate kinase activity
EIH08_RS12015	COG0653	protein targeting
EIH08_RS12025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIH08_RS12045	COG1505	serine-type exopeptidase activity
EIH08_RS12060	COG0482	sulfurtransferase activity
EIH08_RS12065	COG3279	Response regulator of the LytR AlgR family
EIH08_RS12100	COG2032	superoxide dismutase activity
EIH08_RS12105	COG0792	nuclease activity
EIH08_RS12110	COG1619	proteins homologs of microcin C7 resistance protein MccF
EIH08_RS12120	COG0557	exoribonuclease II activity
EIH08_RS12125	COG0698	ribose 5-phosphate isomerase
EIH08_RS12130	COG0126	phosphoglycerate kinase activity
EIH08_RS12145	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EIH08_RS12155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EIH08_RS12160	COG1435	thymidine kinase activity
EIH08_RS12170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EIH08_RS12175	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EIH08_RS12195	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EIH08_RS12200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EIH08_RS12220	COG0628	permease
EIH08_RS12265	COG3118	belongs to the thioredoxin family
EIH08_RS12290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIH08_RS12290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EIH08_RS12295	COG0730	response to heat
EIH08_RS12300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EIH08_RS12435	COG0202	RNA polymerase activity
EIH08_RS12485	COG1192	Involved in chromosome partitioning