locus-tag	class	description
CI104_RS00010	COG0592	DNA-directed DNA polymerase activity
CI104_RS00025	COG0561	phosphatase activity
CI104_RS00030	COG2186	Transcriptional regulator
CI104_RS00035	COG3734	2-keto-3-deoxy-galactonokinase
CI104_RS00040	COG0800	Aldolase
CI104_RS00045	COG4948	Mandelate Racemase Muconate Lactonizing
CI104_RS00050	COG2271	Major facilitator Superfamily
CI104_RS00060	COG0823	Involved in the tonB-independent uptake of proteins
CI104_RS00065	COG5645	(Lipo)protein
CI104_RS00090	COG2188	Transcriptional regulator
CI104_RS00105	COG2149	membrane
CI104_RS00115	COG0641	radical SAM
CI104_RS00125	COG2610	gluconate transmembrane transporter activity
CI104_RS00130	COG0583	DNA-binding transcription factor activity
CI104_RS00140	COG2814	Major facilitator Superfamily
CI104_RS00165	COG0028	Belongs to the TPP enzyme family
CI104_RS00170	COG0440	acetolactate synthase activity
CI104_RS00175	COG1349	DNA-binding transcription factor activity
CI104_RS00185	COG0738	Major facilitator superfamily
CI104_RS00195	COG2197	response regulator
CI104_RS00220	COG2252	PERMEase
CI104_RS00245	COG4580	involved in the transport of maltose and maltodextrins
CI104_RS00250	COG1447	Phosphotransferase system cellobiose-specific component IIA
CI104_RS00255	COG2723	6-phospho-beta-galactosidase activity
CI104_RS00260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI104_RS00270	COG1609	Transcriptional regulator
CI104_RS00300	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI104_RS00300	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS00305	COG3715	PTS system
CI104_RS00310	COG3716	PTS system mannose fructose sorbose family IID component
CI104_RS00325	COG1464	Belongs to the NlpA lipoprotein family
CI104_RS00330	COG0697	spore germination
CI104_RS00340	COG0583	DNA-binding transcription factor activity
CI104_RS00350	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS00365	COG1902	pentaerythritol trinitrate reductase activity
CI104_RS00375	COG2188	Transcriptional regulator
CI104_RS00380	COG2222	sugar isomerase
CI104_RS00385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS00390	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CI104_RS00400	COG2211	Major facilitator Superfamily
CI104_RS00405	COG1501	Belongs to the glycosyl hydrolase 31 family
CI104_RS00410	COG0738	Major facilitator superfamily
CI104_RS00420	COG1486	melibiose metabolic process
CI104_RS00425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI104_RS00425	COG1263	PTS System
CI104_RS00430	COG2982	Protein involved in outer membrane biogenesis
CI104_RS00435	COG2233	PERMEase
CI104_RS00440	COG0786	glutamate:sodium symporter activity
CI104_RS00445	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CI104_RS00450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CI104_RS00455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CI104_RS00475	COG2860	membrane
CI104_RS00480	COG1561	YicC-like family, N-terminal region
CI104_RS00510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CI104_RS00525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CI104_RS00540	COG1519	Transferase
CI104_RS00545	COG0859	PFAM glycosyl transferase family 9
CI104_RS00550	COG0438	transferase activity, transferring glycosyl groups
CI104_RS00555	COG0515	serine threonine protein kinase
CI104_RS00590	COG0859	PFAM glycosyl transferase family 9
CI104_RS00595	COG3307	-O-antigen
CI104_RS00600	COG0859	PFAM glycosyl transferase family 9
CI104_RS00605	COG0859	PFAM glycosyl transferase family 9
CI104_RS00615	COG0156	8-amino-7-oxononanoate synthase activity
CI104_RS00625	COG1216	Glycosyl transferase, family 2
CI104_RS00630	COG2861	carbohydrate metabolic process
CI104_RS00635	COG4942	peptidase
CI104_RS00650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CI104_RS00655	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CI104_RS00675	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CI104_RS00680	COG2271	Major facilitator Superfamily
CI104_RS00690	COG2186	Transcriptional regulator
CI104_RS00710	COG3722	fumarate hydratase activity
CI104_RS00720	COG2213	PTS system mannitol-specific
CI104_RS00720	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS00730	COG1566	PFAM secretion protein HlyD family protein
CI104_RS00735	COG0625	glutathione transferase activity
CI104_RS00745	COG3276	selenocysteine insertion sequence binding
CI104_RS00750	COG1454	alcohol dehydrogenase
CI104_RS00755	COG1012	belongs to the aldehyde dehydrogenase family
CI104_RS00770	COG1566	PFAM secretion protein HlyD family protein
CI104_RS00775	COG0583	DNA-binding transcription factor activity
CI104_RS00780	COG3713	MltA-interacting MipA family protein
CI104_RS00790	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI104_RS00795	COG3977	Valine--pyruvate aminotransferase
CI104_RS00800	COG0366	Alpha amylase catalytic
CI104_RS00810	COG2992	FlgJ-related protein
CI104_RS00815	COG1609	Transcriptional regulator
CI104_RS00815	COG2207	Transcriptional regulator
CI104_RS00820	COG4214	carbohydrate transport
CI104_RS00830	COG4213	ABC transporter substrate-binding protein
CI104_RS00840	COG1070	Carbohydrate kinase
CI104_RS00845	COG4682	membrane
CI104_RS00850	COG3274	enterobacterial common antigen metabolic process
CI104_RS00860	COG0752	glycyl-tRNA synthetase alpha subunit
CI104_RS00875	COG1278	Cold shock
CI104_RS00880	COG2944	sequence-specific DNA binding
CI104_RS00885	COG2814	Major facilitator Superfamily
CI104_RS00905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS00915	COG1609	Transcriptional regulator
CI104_RS00920	COG2885	chlorophyll binding
CI104_RS00925	COG0243	molybdopterin cofactor binding
CI104_RS00930	COG0456	acetyltransferase
CI104_RS00935	COG2818	Glycosylase
CI104_RS00940	COG5571	outer membrane autotransporter
CI104_RS00945	COG2223	nitrite transmembrane transporter activity
CI104_RS00950	COG2194	sulfuric ester hydrolase activity
CI104_RS00985	COG0747	negative chemotaxis
CI104_RS00995	COG0601	transmembrane transport
CI104_RS01000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CI104_RS01005	COG0444	Belongs to the ABC transporter superfamily
CI104_RS01010	COG4608	Belongs to the ABC transporter superfamily
CI104_RS01015	COG0814	amino acid
CI104_RS01050	COG1215	transferase activity, transferring glycosyl groups
CI104_RS01055	COG1215	transferase activity, transferring glycosyl groups
CI104_RS01065	COG0457	Tetratricopeptide repeat
CI104_RS01065	COG3118	belongs to the thioredoxin family
CI104_RS01070	COG2199	diguanylate cyclase activity
CI104_RS01070	COG2200	EAL domain
CI104_RS01085	COG0612	Peptidase, M16
CI104_RS01090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS01095	COG2200	EAL domain
CI104_RS01100	COG2982	Protein involved in outer membrane biogenesis
CI104_RS01105	COG0477	Major facilitator Superfamily
CI104_RS01115	COG1295	ribonuclease BN
CI104_RS01120	COG0583	DNA-binding transcription factor activity
CI104_RS01125	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS01130	COG2197	response regulator
CI104_RS01135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CI104_RS01150	COG1858	cytochrome C peroxidase
CI104_RS01155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CI104_RS01160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CI104_RS01165	COG0339	signal peptide processing
CI104_RS01180	COG0589	response to stress
CI104_RS01190	COG0306	phosphate transporter
CI104_RS01195	COG2081	HI0933 family
CI104_RS01200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI104_RS01205	COG0842	Transport permease protein
CI104_RS01205	COG1129	ABC transporter
CI104_RS01210	COG0842	Transport permease protein
CI104_RS01230	COG0444	Belongs to the ABC transporter superfamily
CI104_RS01235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CI104_RS01240	COG0601	transmembrane transport
CI104_RS01245	COG0747	negative chemotaxis
CI104_RS01255	COG2091	lysine biosynthetic process via aminoadipic acid
CI104_RS01260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CI104_RS01265	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS01275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CI104_RS01300	COG1216	Glycosyl transferase, family 2
CI104_RS01320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CI104_RS01350	COG0628	permease
CI104_RS01355	COG0477	Major facilitator Superfamily
CI104_RS01365	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CI104_RS01380	COG3714	YhhN family
CI104_RS01390	COG3776	membrane
CI104_RS01395	COG0742	ribosomal rna small subunit methyltransferase
CI104_RS01400	COG0552	protein localization to endoplasmic reticulum
CI104_RS01405	COG2884	Cell division ATP-binding protein ftsE
CI104_RS01410	COG2177	Part of the ABC transporter FtsEX involved in
CI104_RS01420	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CI104_RS01425	COG0683	leucine binding
CI104_RS01430	COG4907	membrane protein (DUF2207)
CI104_RS01435	COG1704	LemA family
CI104_RS01445	COG0683	leucine binding
CI104_RS01455	COG4177	L-phenylalanine transmembrane transporter activity
CI104_RS01460	COG0411	ABC transporter
CI104_RS01465	COG0410	ABC transporter
CI104_RS01490	COG0584	glycerophosphoryl diester phosphodiesterase
CI104_RS01500	COG0405	Gamma-glutamyltransferase
CI104_RS01505	COG1247	-acetyltransferase
CI104_RS01510	COG0673	inositol 2-dehydrogenase activity
CI104_RS01515	COG1741	Belongs to the pirin family
CI104_RS01520	COG1609	Transcriptional regulator
CI104_RS01525	COG3265	gluconokinase activity
CI104_RS01530	COG2610	gluconate transmembrane transporter activity
CI104_RS01535	COG2095	MarC family integral membrane protein
CI104_RS01565	COG0058	SHG alpha-glucan phosphorylase activity
CI104_RS01570	COG1414	Transcriptional regulator
CI104_RS01575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CI104_RS01580	COG0129	dihydroxy-acid dehydratase activity
CI104_RS01590	COG0371	Dehydrogenase
CI104_RS01595	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CI104_RS01610	COG1349	DNA-binding transcription factor activity
CI104_RS01615	COG0183	Belongs to the thiolase family
CI104_RS01620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CI104_RS01625	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CI104_RS01640	COG2851	Citrate transporter
CI104_RS01655	COG0058	SHG alpha-glucan phosphorylase activity
CI104_RS01660	COG1640	4-alpha-glucanotransferase
CI104_RS01665	COG2610	gluconate transmembrane transporter activity
CI104_RS01685	COG5464	transposase or invertase
CI104_RS01700	COG1918	ferrous iron import across plasma membrane
CI104_RS01710	COG2183	response to ionizing radiation
CI104_RS01715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CI104_RS01740	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CI104_RS01745	COG1011	Hydrolase
CI104_RS01755	COG0494	nUDIX hydrolase
CI104_RS01760	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CI104_RS01765	COG4972	Pilus assembly protein
CI104_RS01770	COG3166	PFAM Fimbrial assembly family protein
CI104_RS01785	COG4796	Type ii and iii secretion system protein
CI104_RS01800	COG3266	domain, Protein
CI104_RS01805	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CI104_RS01810	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CI104_RS01820	COG0180	Tryptophanyl-tRNA synthetase
CI104_RS01825	COG2188	Transcriptional regulator
CI104_RS01835	COG1082	Xylose isomerase domain protein TIM barrel
CI104_RS01840	COG2222	sugar isomerase
CI104_RS01845	COG0531	amino acid
CI104_RS01865	COG2146	nitrite reductase [NAD(P)H] activity
CI104_RS01870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CI104_RS01905	COG1289	transmembrane transporter activity
CI104_RS01920	COG1765	OsmC-like protein
CI104_RS01925	COG3954	Phosphoribulokinase
CI104_RS01935	COG0429	hydrolase of the alpha beta-hydrolase fold
CI104_RS01940	COG0488	(ABC) transporter
CI104_RS01960	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CI104_RS01965	COG1047	Peptidyl-prolyl cis-trans
CI104_RS01975	COG0545	Peptidyl-prolyl cis-trans isomerase
CI104_RS01980	COG2964	Protein conserved in bacteria
CI104_RS02040	COG0051	transcription antitermination factor activity, RNA binding
CI104_RS02145	COG0201	protein transport
CI104_RS02175	COG0203	ribosomal protein L17
CI104_RS02185	COG0789	Transcriptional regulator
CI104_RS02190	COG3036	rescue of stalled ribosome
CI104_RS02220	COG0758	DNA mediated transformation
CI104_RS02230	COG0551	DNA topoisomerase type I activity
CI104_RS02250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CI104_RS02290	COG1126	abc transporter atp-binding protein
CI104_RS02295	COG0765	amino acid transport
CI104_RS02300	COG4597	amino acid ABC transporter
CI104_RS02305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI104_RS02320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CI104_RS02325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI104_RS02345	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CI104_RS02370	COG4145	pantothenate transmembrane transporter activity
CI104_RS02375	COG3924	membrane
CI104_RS02380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS02385	COG1349	DNA-binding transcription factor activity
CI104_RS02395	COG1879	ABC-type sugar transport system periplasmic component
CI104_RS02400	COG1129	ABC transporter
CI104_RS02405	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI104_RS02410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS02420	COG0439	Biotin carboxylase
CI104_RS02425	COG0511	ligase activity, forming carbon-carbon bonds
CI104_RS02445	COG0604	alcohol dehydrogenase
CI104_RS02450	COG2199	diguanylate cyclase activity
CI104_RS02450	COG2200	EAL domain
CI104_RS02465	COG1077	Cell shape determining protein MreB Mrl
CI104_RS02470	COG1792	Involved in formation and maintenance of cell shape
CI104_RS02475	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CI104_RS02490	COG3164	Protein of unknown function
CI104_RS02495	COG0312	modulator of DNA gyrase
CI104_RS02500	COG0583	DNA-binding transcription factor activity
CI104_RS02520	COG1012	belongs to the aldehyde dehydrogenase family
CI104_RS02525	COG2732	(Barnase) inhibitor
CI104_RS02545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CI104_RS02550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CI104_RS02555	COG3105	Protein conserved in bacteria
CI104_RS02560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CI104_RS02585	COG0625	glutathione transferase activity
CI104_RS02590	COG2969	positive regulation of protein catabolic process
CI104_RS02595	COG2186	Transcriptional regulator
CI104_RS02620	COG2731	YhcH YjgK YiaL family protein
CI104_RS02625	COG4804	nuclease activity
CI104_RS02630	COG0493	'glutamate synthase
CI104_RS02635	COG0069	glutamate synthase activity
CI104_RS02635	COG0070	glutamate synthase
CI104_RS02635	COG0067	glutamate synthase
CI104_RS02650	COG1242	4 iron, 4 sulfur cluster binding
CI104_RS02655	COG2198	Histidine kinase
CI104_RS02655	COG0784	Response regulator, receiver
CI104_RS02655	COG5002	protein histidine kinase activity
CI104_RS02660	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CI104_RS02670	COG0515	serine threonine protein kinase
CI104_RS02675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS02690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CI104_RS02695	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CI104_RS02700	COG1137	ATPase activity
CI104_RS02705	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CI104_RS02710	COG3117	lipopolysaccharide transmembrane transporter activity
CI104_RS02715	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CI104_RS02725	COG0530	calcium, potassium:sodium antiporter activity
CI104_RS02730	COG1127	ABC transporter
CI104_RS02735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CI104_RS02740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CI104_RS02745	COG2854	intermembrane phospholipid transfer
CI104_RS02750	COG3113	response to antibiotic
CI104_RS02755	COG5007	Belongs to the BolA IbaG family
CI104_RS02765	COG3423	Transcriptional regulator
CI104_RS02770	COG0142	geranyltranstransferase activity
CI104_RS02785	COG0697	spore germination
CI104_RS02795	COG2027	D-alanyl-D-alanine carboxypeptidase
CI104_RS02805	COG1534	Rna-binding protein
CI104_RS02815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CI104_RS02820	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CI104_RS02830	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CI104_RS02840	COG0583	DNA-binding transcription factor activity
CI104_RS02850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CI104_RS02860	COG1301	dicarboxylic acid transport
CI104_RS02865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CI104_RS02890	COG0195	Participates in both transcription termination and antitermination
CI104_RS02925	COG0513	Belongs to the DEAD box helicase family
CI104_RS02930	COG0814	amino acid
CI104_RS02935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CI104_RS02940	COG0826	peptidase U32
CI104_RS02945	COG0826	peptidase U32
CI104_RS02950	COG3154	lipid carrier protein
CI104_RS02955	COG3153	acetyltransferase
CI104_RS02970	COG0693	protein deglycase activity
CI104_RS02975	COG0702	epimerase
CI104_RS02980	COG0701	Predicted permease
CI104_RS02985	COG2823	Periplasmic or secreted lipoprotein
CI104_RS03005	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CI104_RS03010	COG0363	glucosamine-6-phosphate deaminase activity
CI104_RS03015	COG3716	PTS system mannose fructose sorbose family IID component
CI104_RS03020	COG3715	PTS system
CI104_RS03025	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI104_RS03035	COG2222	sugar isomerase
CI104_RS03040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CI104_RS03045	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS03050	COG3716	PTS system mannose fructose sorbose family IID component
CI104_RS03060	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI104_RS03075	COG1349	DNA-binding transcription factor activity
CI104_RS03080	COG1349	DNA-binding transcription factor activity
CI104_RS03085	COG1940	carbohydrate kinase activity
CI104_RS03090	COG0673	inositol 2-dehydrogenase activity
CI104_RS03095	COG3842	ATPase activity
CI104_RS03100	COG0395	ABC-type sugar transport system, permease component
CI104_RS03105	COG1175	transmembrane transport
CI104_RS03115	COG2721	sulfolactate sulfo-lyase activity
CI104_RS03120	COG2271	Major facilitator Superfamily
CI104_RS03130	COG2084	Dehydrogenase
CI104_RS03135	COG1929	Belongs to the glycerate kinase type-1 family
CI104_RS03145	COG0583	DNA-binding transcription factor activity
CI104_RS03165	COG1882	Formate acetyltransferase
CI104_RS03170	COG1760	l-serine dehydratase
CI104_RS03175	COG0814	amino acid
CI104_RS03190	COG1741	Belongs to the pirin family
CI104_RS03195	COG0583	DNA-binding transcription factor activity
CI104_RS03200	COG3152	Membrane
CI104_RS03205	COG0435	Glutathione S-transferase
CI104_RS03210	COG2259	Doxx family
CI104_RS03220	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CI104_RS03225	COG4575	ribosome binding
CI104_RS03230	COG1422	Protein of unknown function (DUF1090)
CI104_RS03240	COG0586	Pfam SNARE associated Golgi protein
CI104_RS03245	COG2186	Transcriptional regulator
CI104_RS03250	COG2271	Major facilitator Superfamily
CI104_RS03260	COG2721	sulfolactate sulfo-lyase activity
CI104_RS03275	COG0861	Integral membrane protein TerC family
CI104_RS03280	COG0673	inositol 2-dehydrogenase activity
CI104_RS03285	COG1451	nucleotide metabolic process
CI104_RS03300	COG4680	protein conserved in bacteria
CI104_RS03305	COG5499	transcription regulator containing HTH domain
CI104_RS03310	COG1902	pentaerythritol trinitrate reductase activity
CI104_RS03310	COG0446	pyridine nucleotide-disulphide oxidoreductase
CI104_RS03325	COG1609	Transcriptional regulator
CI104_RS03330	COG1653	transport
CI104_RS03335	COG1175	transmembrane transport
CI104_RS03340	COG0395	ABC-type sugar transport system, permease component
CI104_RS03345	COG0366	Alpha amylase catalytic
CI104_RS03350	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CI104_RS03355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CI104_RS03365	COG0840	transmembrane signaling receptor activity
CI104_RS03370	COG0840	transmembrane signaling receptor activity
CI104_RS03375	COG1695	Transcriptional regulator
CI104_RS03380	COG2375	cellular response to nickel ion
CI104_RS03415	COG4974	Belongs to the 'phage' integrase family
CI104_RS03455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CI104_RS03495	COG4695	Portal protein
CI104_RS03645	COG3663	DNA glycosylase
CI104_RS03650	COG4771	TonB-dependent receptor
CI104_RS03655	COG3391	amine dehydrogenase activity
CI104_RS03665	COG0358	DNA primase activity
CI104_RS03670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CI104_RS03725	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CI104_RS03730	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CI104_RS03745	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CI104_RS03760	COG4991	sh3 domain protein
CI104_RS03770	COG3025	triphosphatase activity
CI104_RS03810	COG3384	dioxygenase
CI104_RS03815	COG0754	glutathionylspermidine amidase activity
CI104_RS03830	COG1538	Outer membrane efflux protein
CI104_RS03835	COG0494	nUDIX hydrolase
CI104_RS03840	COG3151	Protein conserved in bacteria
CI104_RS03845	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CI104_RS03850	COG3150	esterase
CI104_RS03855	COG0187	DNA topoisomerase II activity
CI104_RS03870	COG2211	Major facilitator Superfamily
CI104_RS03875	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CI104_RS03880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CI104_RS03885	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CI104_RS03890	COG2249	NAD(P)H dehydrogenase (quinone) activity
CI104_RS03895	COG0642	Histidine kinase
CI104_RS03900	COG0745	RESPONSE REGULATOR receiver
CI104_RS03905	COG3111	PFAM Bacterial OB fold (BOF) protein
CI104_RS03915	COG0204	Acyl-transferase
CI104_RS03935	COG0656	L-ascorbic acid biosynthetic process
CI104_RS03940	COG1979	alcohol dehydrogenase
CI104_RS03950	COG2207	Transcriptional regulator
CI104_RS03955	COG0586	Pfam SNARE associated Golgi protein
CI104_RS03960	COG0626	cystathionine gamma-synthase activity
CI104_RS03970	COG0811	peptide transport
CI104_RS03975	COG0848	biopolymer transport protein
CI104_RS04000	COG0667	Aldo Keto reductase
CI104_RS04010	COG0840	transmembrane signaling receptor activity
CI104_RS04020	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CI104_RS04025	COG0437	4 iron, 4 sulfur cluster binding
CI104_RS04030	COG5557	Pfam Polysulphide reductase, NrfD
CI104_RS04035	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CI104_RS04040	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CI104_RS04045	COG1773	rubredoxin
CI104_RS04055	COG0298	carbon dioxide binding
CI104_RS04060	COG0625	glutathione transferase activity
CI104_RS04065	COG0754	glutathionylspermidine amidase activity
CI104_RS04070	COG2390	Transcriptional regulator
CI104_RS04095	COG4932	domain protein
CI104_RS04095	COG1388	LysM domain
CI104_RS04095	COG2373	Large extracellular alpha-helical protein
CI104_RS04105	COG3121	Chaperone
CI104_RS04115	COG1811	Na channel or pump
CI104_RS04125	COG1982	Orn Lys Arg decarboxylase major
CI104_RS04130	COG2211	Major facilitator Superfamily
CI104_RS04145	COG1194	a g-specific adenine glycosylase
CI104_RS04160	COG3171	Protein conserved in bacteria
CI104_RS04170	COG0252	asparaginase activity
CI104_RS04175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CI104_RS04190	COG0762	integral membrane protein
CI104_RS04195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CI104_RS04200	COG2805	Type II/IV secretion system protein
CI104_RS04215	COG0189	ligase activity
CI104_RS04220	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CI104_RS04225	COG2356	endonuclease I
CI104_RS04230	COG3091	SprT-like family
CI104_RS04235	COG2814	Major facilitator Superfamily
CI104_RS04260	COG1166	arginine decarboxylase activity
CI104_RS04270	COG0501	Belongs to the peptidase M48B family
CI104_RS04275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CI104_RS04280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS04285	COG2213	PTS system mannitol-specific
CI104_RS04290	COG1063	alcohol dehydrogenase
CI104_RS04295	COG1494	fructose-1,6-bisphosphatase
CI104_RS04305	COG1072	(Pantothenic acid kinase))
CI104_RS04310	COG1122	ATPase activity
CI104_RS04315	COG1122	ATPase activity
CI104_RS04345	COG0191	fructose-bisphosphate aldolase activity
CI104_RS04350	COG0549	Belongs to the carbamate kinase family
CI104_RS04355	COG2271	Major facilitator Superfamily
CI104_RS04360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CI104_RS04365	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CI104_RS04375	COG0583	DNA-binding transcription factor activity
CI104_RS04380	COG0668	transmembrane transport
CI104_RS04385	COG1279	arginine transmembrane transporter activity
CI104_RS04390	COG2968	Membrane
CI104_RS04395	COG0488	(ABC) transporter
CI104_RS04400	COG0741	lytic transglycosylase activity
CI104_RS04420	COG2207	Transcriptional regulator
CI104_RS04420	COG3708	Transcriptional regulator
CI104_RS04425	COG3045	CreA protein
CI104_RS04430	COG0745	RESPONSE REGULATOR receiver
CI104_RS04435	COG2205	protein histidine kinase activity
CI104_RS04440	COG4452	Inner membrane protein CreD
CI104_RS04445	COG0745	RESPONSE REGULATOR receiver
CI104_RS04455	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CI104_RS04465	COG0527	aspartate kinase activity
CI104_RS04465	COG0460	homoserine dehydrogenase
CI104_RS04475	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CI104_RS04485	COG1115	amino acid carrier protein
CI104_RS04495	COG0521	Mo-molybdopterin cofactor biosynthetic process
CI104_RS04500	COG0477	Major facilitator Superfamily
CI104_RS04505	COG1584	GPR1 FUN34 yaaH family protein
CI104_RS04525	COG0583	DNA-binding transcription factor activity
CI104_RS04540	COG0196	riboflavin kinase activity
CI104_RS04555	COG1047	Peptidyl-prolyl cis-trans
CI104_RS04570	COG2140	Oxalate decarboxylase
CI104_RS04580	COG3716	PTS system mannose fructose sorbose family IID component
CI104_RS04585	COG3715	PTS system
CI104_RS04590	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS04590	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI104_RS04605	COG1609	Transcriptional regulator
CI104_RS04645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CI104_RS04670	COG0644	oxidoreductase
CI104_RS04680	COG2271	Major facilitator Superfamily
CI104_RS04730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CI104_RS04735	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CI104_RS04740	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CI104_RS04745	COG0564	pseudouridine synthase activity
CI104_RS04755	COG0417	DNA replication proofreading
CI104_RS04760	COG0235	Class ii aldolase
CI104_RS04775	COG4977	sequence-specific DNA binding
CI104_RS04780	COG0586	Pfam SNARE associated Golgi protein
CI104_RS04785	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CI104_RS04790	COG1178	ABC-type Fe3 transport system permease component
CI104_RS04810	COG2814	Major facilitator Superfamily
CI104_RS04840	COG0028	Belongs to the TPP enzyme family
CI104_RS04850	COG1609	Transcriptional regulator
CI104_RS04870	COG0768	penicillin binding
CI104_RS04875	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CI104_RS04880	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CI104_RS04885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CI104_RS04895	COG0772	Belongs to the SEDS family
CI104_RS04910	COG1181	Belongs to the D-alanine--D-alanine ligase family
CI104_RS04920	COG0849	cell division
CI104_RS04925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CI104_RS04945	COG0494	nUDIX hydrolase
CI104_RS04970	COG1459	type II secretion system
CI104_RS04975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CI104_RS04980	COG4969	Belongs to the N-Me-Phe pilin family
CI104_RS04995	COG3725	Membrane protein required for beta-lactamase induction
CI104_RS05000	COG1113	amino acid transport
CI104_RS05005	COG2186	Transcriptional regulator
CI104_RS05010	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CI104_RS05015	COG0508	dehydrogenase complex catalyzes the overall conversion of
CI104_RS05020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CI104_RS05030	COG3064	Membrane
CI104_RS05060	COG1349	DNA-binding transcription factor activity
CI104_RS05095	COG5434	Belongs to the glycosyl hydrolase 28 family
CI104_RS05100	COG4993	Dehydrogenase
CI104_RS05105	COG2831	hemolysin activation secretion protein
CI104_RS05110	COG3210	domain, Protein
CI104_RS05115	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CI104_RS05120	COG0288	reversible hydration of carbon dioxide
CI104_RS05125	COG1131	(ABC) transporter
CI104_RS05130	COG0842	Transport permease protein
CI104_RS05135	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS05140	COG0726	polysaccharide deacetylase
CI104_RS05160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CI104_RS05170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CI104_RS05185	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CI104_RS05190	COG1643	Atp-dependent helicase
CI104_RS05195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CI104_RS05200	COG4774	siderophore transport
CI104_RS05205	COG1120	ATPase activity
CI104_RS05210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CI104_RS05215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI104_RS05235	COG2860	membrane
CI104_RS05255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CI104_RS05260	COG3835	regulator
CI104_RS05315	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CI104_RS05325	COG0575	Belongs to the CDS family
CI104_RS05340	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CI104_RS05380	COG1982	Orn Lys Arg decarboxylase major
CI104_RS05385	COG0346	lactoylglutathione lyase activity
CI104_RS05390	COG0037	tRNA processing
CI104_RS05395	COG4568	rho-dependent transcription termination
CI104_RS05410	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CI104_RS05415	COG3015	lipoprotein NlpE involved in copper resistance
CI104_RS05420	COG0791	NLP P60 protein
CI104_RS05430	COG1720	tRNA m6t6A37 methyltransferase activity
CI104_RS05440	COG1464	Belongs to the NlpA lipoprotein family
CI104_RS05445	COG2011	ABC-type metal ion transport system permease component
CI104_RS05455	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CI104_RS05490	COG0583	DNA-binding transcription factor activity
CI104_RS05495	COG2814	Major facilitator Superfamily
CI104_RS05505	COG2226	methyltransferase
CI104_RS05510	COG1388	LysM domain
CI104_RS05510	COG0741	lytic transglycosylase activity
CI104_RS05520	COG2226	methyltransferase
CI104_RS05530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CI104_RS05685	COG3209	COG3209 Rhs family protein
CI104_RS05705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CI104_RS05710	COG1960	acyl-CoA dehydrogenase activity
CI104_RS05720	COG0121	glutamine amidotransferase
CI104_RS05725	COG3034	peptidoglycan biosynthetic process
CI104_RS05730	COG0791	NLP P60 protein
CI104_RS05755	COG2195	Cleaves the N-terminal amino acid of tripeptides
CI104_RS05775	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CI104_RS05795	COG0217	transcriptional regulatory protein
CI104_RS05805	COG2199	diguanylate cyclase activity
CI104_RS05840	COG2226	methyltransferase
CI104_RS05865	COG1280	lysine exporter protein (LysE YggA)
CI104_RS05885	COG3829	transcription factor binding
CI104_RS05930	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CI104_RS05940	COG3842	ATPase activity
CI104_RS05950	COG1840	ABC-type Fe3 transport system, periplasmic component
CI104_RS05955	COG2271	Major facilitator Superfamily
CI104_RS05975	COG4521	taurine ABC transporter
CI104_RS05980	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CI104_RS05985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CI104_RS05990	COG2175	clavaminate synthase activity
CI104_RS06000	COG0113	porphobilinogen synthase activity
CI104_RS06005	COG3468	outer membrane autotransporter barrel domain protein
CI104_RS06010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CI104_RS06015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CI104_RS06025	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CI104_RS06045	COG1181	Belongs to the D-alanine--D-alanine ligase family
CI104_RS06065	COG1785	Belongs to the alkaline phosphatase family
CI104_RS06075	COG3706	GGDEF domain
CI104_RS06080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CI104_RS06100	COG4126	flavin adenine dinucleotide binding
CI104_RS06115	COG1940	carbohydrate kinase activity
CI104_RS06120	COG0419	ATPase involved in DNA repair
CI104_RS06125	COG0420	3'-5' exonuclease activity
CI104_RS06130	COG0745	RESPONSE REGULATOR receiver
CI104_RS06135	COG5002	protein histidine kinase activity
CI104_RS06145	COG1113	amino acid transport
CI104_RS06150	COG0366	Alpha amylase catalytic
CI104_RS06155	COG0583	DNA-binding transcription factor activity
CI104_RS06160	COG1335	isochorismatase
CI104_RS06170	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CI104_RS06190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS06195	COG3037	sugar-specific permease SgaT UlaA
CI104_RS06205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS06210	COG0450	alkyl hydroperoxide reductase
CI104_RS06230	COG1862	Preprotein translocase
CI104_RS06235	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CI104_RS06240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CI104_RS06255	COG3248	Nucleoside-binding outer membrane protein
CI104_RS06260	COG4238	major outer membrane lipoprotein
CI104_RS06270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CI104_RS06270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CI104_RS06290	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CI104_RS06295	COG0667	Aldo Keto reductase
CI104_RS06305	COG0142	geranyltranstransferase activity
CI104_RS06325	COG0243	molybdopterin cofactor binding
CI104_RS06330	COG0437	4 iron, 4 sulfur cluster binding
CI104_RS06345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CI104_RS06355	COG2814	Major facilitator Superfamily
CI104_RS06375	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CI104_RS06380	COG1845	cytochrome c oxidase, subunit III
CI104_RS06385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CI104_RS06390	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CI104_RS06395	COG2223	nitrite transmembrane transporter activity
CI104_RS06400	COG3056	Lipoprotein
CI104_RS06405	COG0271	Belongs to the BolA IbaG family
CI104_RS06430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CI104_RS06435	COG0776	regulation of translation
CI104_RS06440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CI104_RS06445	COG1555	photosystem II stabilization
CI104_RS06450	COG0824	Thioesterase
CI104_RS06460	COG4533	DNA binding
CI104_RS06475	COG1522	sequence-specific DNA binding
CI104_RS06480	COG1132	(ABC) transporter
CI104_RS06485	COG1132	(ABC) transporter
CI104_RS06490	COG0347	Belongs to the P(II) protein family
CI104_RS06495	COG0004	ammonium transporteR
CI104_RS06500	COG1946	Acyl-CoA thioesterase
CI104_RS06505	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CI104_RS06510	COG3695	enzyme binding
CI104_RS06530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CI104_RS06535	COG2364	Membrane
CI104_RS06540	COG5507	3-demethylubiquinone-9 3-methyltransferase
CI104_RS06545	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CI104_RS06550	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CI104_RS06560	COG0110	maltose O-acetyltransferase activity
CI104_RS06575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CI104_RS06580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI104_RS06585	COG1309	transcriptional regulator
CI104_RS06595	COG1196	nuclear chromosome segregation
CI104_RS06595	COG3264	Mechanosensitive ion channel
CI104_RS06605	COG3923	Primosomal replication protein n
CI104_RS06610	COG2832	Protein of unknown function (DUF454)
CI104_RS06665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS06670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CI104_RS06670	COG4651	solute:proton antiporter activity
CI104_RS06675	COG2223	nitrite transmembrane transporter activity
CI104_RS06690	COG3735	TraB family
CI104_RS06695	COG2217	Heavy metal translocating P-type atpase
CI104_RS06725	COG5301	cellulose 1,4-beta-cellobiosidase activity
CI104_RS06820	COG4695	Portal protein
CI104_RS06845	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CI104_RS06870	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CI104_RS06875	COG1285	pathogenesis
CI104_RS06885	COG1609	Transcriptional regulator
CI104_RS06890	COG0477	Major facilitator Superfamily
CI104_RS06910	COG1585	Membrane protein implicated in regulation of membrane protease activity
CI104_RS06915	COG0330	HflC and HflK could
CI104_RS06920	COG4619	ABC transporter
CI104_RS06925	COG0390	transport system, permease component
CI104_RS06930	COG3118	belongs to the thioredoxin family
CI104_RS06935	COG0300	oxidoreductase activity
CI104_RS06940	COG2755	lipolytic protein G-D-S-L family
CI104_RS06945	COG4181	ATPase activity
CI104_RS06950	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CI104_RS06965	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CI104_RS06970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CI104_RS06985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CI104_RS06995	COG1988	membrane-bound metal-dependent
CI104_RS07010	COG0545	Peptidyl-prolyl cis-trans isomerase
CI104_RS07015	COG1609	Transcriptional regulator
CI104_RS07020	COG2190	(PTS) system
CI104_RS07020	COG1263	PTS System
CI104_RS07020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI104_RS07025	COG2501	S4 domain
CI104_RS07050	COG5002	protein histidine kinase activity
CI104_RS07055	COG0745	RESPONSE REGULATOR receiver
CI104_RS07060	COG1538	Outer membrane efflux protein
CI104_RS07065	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI104_RS07070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI104_RS07075	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CI104_RS07115	COG1113	amino acid transport
CI104_RS07120	COG2211	Major facilitator Superfamily
CI104_RS07135	COG1609	Transcriptional regulator
CI104_RS07140	COG0668	transmembrane transport
CI104_RS07145	COG0778	Nitroreductase
CI104_RS07150	COG2315	Protein conserved in bacteria
CI104_RS07205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CI104_RS07220	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS07225	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS07230	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI104_RS07235	COG1129	ABC transporter
CI104_RS07245	COG1879	ABC-type sugar transport system periplasmic component
CI104_RS07250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CI104_RS07255	COG2390	Transcriptional regulator
CI104_RS07260	COG3959	Transketolase, thiamine diphosphate binding domain
CI104_RS07265	COG3958	Transketolase
CI104_RS07270	COG2977	Belongs to the P-Pant transferase superfamily
CI104_RS07275	COG4771	TonB-dependent receptor
CI104_RS07285	COG2382	esterase
CI104_RS07290	COG3251	PFAM MbtH domain protein
CI104_RS07295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CI104_RS07295	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CI104_RS07300	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CI104_RS07305	COG1120	ATPase activity
CI104_RS07310	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI104_RS07315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI104_RS07325	COG4592	Periplasmic binding protein
CI104_RS07330	COG1169	isochorismate synthase
CI104_RS07335	COG1021	2,3-dihydroxybenzoate-AMP ligase
CI104_RS07340	COG3433	isochorismatase activity
CI104_RS07340	COG1535	isochorismatase
CI104_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS07355	COG1966	Carbon starvation protein
CI104_RS07360	COG2879	small protein
CI104_RS07365	COG1475	DNA binding
CI104_RS07370	COG3969	phosphoadenosine phosphosulfate
CI104_RS07375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CI104_RS07385	COG3634	alkyl hydroperoxide reductase activity
CI104_RS07400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CI104_RS07410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CI104_RS07415	COG3719	Belongs to the RNase T2 family
CI104_RS07420	COG0471	metal ion transport
CI104_RS07435	COG3051	citrate lyase alpha subunit
CI104_RS07440	COG2301	Belongs to the HpcH HpaI aldolase family
CI104_RS07450	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CI104_RS07455	COG3290	protein histidine kinase activity
CI104_RS07460	COG4565	transcriptional regulatory protein
CI104_RS07465	COG3069	C4-dicarboxylate transmembrane transporter activity
CI104_RS07485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CI104_RS07500	COG0583	DNA-binding transcription factor activity
CI104_RS07515	COG1686	Belongs to the peptidase S11 family
CI104_RS07520	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CI104_RS07525	COG0772	Belongs to the SEDS family
CI104_RS07530	COG0768	penicillin binding
CI104_RS07540	COG0799	negative regulation of ribosome biogenesis
CI104_RS07560	COG1466	dna polymerase III delta subunit
CI104_RS07575	COG2888	peptidyl-tyrosine sulfation
CI104_RS07585	COG1126	abc transporter atp-binding protein
CI104_RS07590	COG0765	amino acid transport
CI104_RS07595	COG0765	amino acid transport
CI104_RS07610	COG4535	Mg2 and Co2 transporter CorC
CI104_RS07620	COG1702	phosphate starvation-inducible protein PhoH
CI104_RS07630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CI104_RS07670	COG0367	asparagine synthase
CI104_RS07680	COG0647	UMP catabolic process
CI104_RS07685	COG1940	carbohydrate kinase activity
CI104_RS07685	COG1846	Transcriptional regulator
CI104_RS07690	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CI104_RS07705	COG2190	(PTS) system
CI104_RS07705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI104_RS07705	COG1263	PTS System
CI104_RS07735	COG1053	succinate dehydrogenase
CI104_RS07745	COG0735	belongs to the Fur family
CI104_RS07750	COG0716	FMN binding
CI104_RS07760	COG0596	Alpha beta hydrolase
CI104_RS07765	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CI104_RS07770	COG0033	Phosphoglucomutase
CI104_RS07775	COG0531	amino acid
CI104_RS07780	COG1982	Orn Lys Arg decarboxylase major
CI104_RS07785	COG0745	RESPONSE REGULATOR receiver
CI104_RS07790	COG2205	protein histidine kinase activity
CI104_RS07820	COG3272	Protein of unknown function (DUF1722)
CI104_RS07825	COG0415	Belongs to the DNA photolyase family
CI104_RS07830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CI104_RS07835	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CI104_RS07840	COG1984	allophanate hydrolase subunit 2
CI104_RS07870	COG3180	Ammonia monooxygenase
CI104_RS07890	COG2009	succinate dehydrogenase
CI104_RS07895	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CI104_RS07900	COG1053	succinate dehydrogenase
CI104_RS07910	COG0567	Dehydrogenase, E1 component
CI104_RS07915	COG0508	dehydrogenase complex catalyzes the overall conversion of
CI104_RS07925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CI104_RS07945	COG3246	L-lysine catabolic process to acetate
CI104_RS07950	COG3622	Belongs to the hyi family
CI104_RS07955	COG1349	DNA-binding transcription factor activity
CI104_RS07960	COG0235	Class ii aldolase
CI104_RS07965	COG3395	kinase activity
CI104_RS07975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CI104_RS07975	COG1648	precorrin-2 dehydrogenase activity
CI104_RS07980	COG0583	DNA-binding transcription factor activity
CI104_RS07985	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CI104_RS07990	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CI104_RS07990	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CI104_RS08000	COG1301	dicarboxylic acid transport
CI104_RS08015	COG3799	methylaspartate ammonia-lyase activity
CI104_RS08020	COG4865	methylaspartate mutase activity
CI104_RS08030	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CI104_RS08035	COG1271	oxidase subunit
CI104_RS08040	COG1294	oxidase, subunit
CI104_RS08045	COG4890	Cyd operon protein YbgT
CI104_RS08050	COG3790	cyd operon protein YbgE
CI104_RS08055	COG0824	Thioesterase
CI104_RS08060	COG0811	peptide transport
CI104_RS08065	COG0848	biopolymer transport protein
CI104_RS08070	COG3064	Membrane
CI104_RS08080	COG2885	chlorophyll binding
CI104_RS08085	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CI104_RS08130	COG3201	nicotinamide mononucleotide transporter
CI104_RS08135	COG1230	cation diffusion facilitator family transporter
CI104_RS08145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CI104_RS08150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI104_RS08170	COG2017	converts alpha-aldose to the beta-anomer
CI104_RS08180	COG1085	galactose-1-phosphate uridylyltransferase
CI104_RS08185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CI104_RS08190	COG1119	ATPase activity
CI104_RS08195	COG2005	Transcriptional regulator
CI104_RS08195	COG3585	molybdate ion transport
CI104_RS08205	COG0725	ABC transporter, periplasmic molybdate-binding protein
CI104_RS08210	COG4149	molybdate abc transporter
CI104_RS08220	COG0561	phosphatase activity
CI104_RS08230	COG4677	pectinesterase activity
CI104_RS08260	COG1881	PFAM PEBP family protein
CI104_RS08285	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CI104_RS08310	COG0521	Mo-molybdopterin cofactor biosynthetic process
CI104_RS08320	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CI104_RS08325	COG0314	molybdopterin synthase activity
CI104_RS08330	COG0670	Belongs to the BI1 family
CI104_RS08335	COG0392	lysyltransferase activity
CI104_RS08340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CI104_RS08345	COG3568	Endonuclease Exonuclease Phosphatase
CI104_RS08355	COG0842	Transport permease protein
CI104_RS08360	COG0842	Transport permease protein
CI104_RS08365	COG1131	(ABC) transporter
CI104_RS08370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI104_RS08375	COG1309	transcriptional regulator
CI104_RS08380	COG0513	Belongs to the DEAD box helicase family
CI104_RS08395	COG2188	Transcriptional regulator
CI104_RS08405	COG0471	metal ion transport
CI104_RS08410	COG1199	ATP-dependent helicase activity
CI104_RS08415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CI104_RS08430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CI104_RS08445	COG0668	transmembrane transport
CI104_RS08450	COG1126	abc transporter atp-binding protein
CI104_RS08455	COG0765	amino acid transport
CI104_RS08460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI104_RS08470	COG5006	permease, DMT superfamily
CI104_RS08475	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CI104_RS08480	COG2194	sulfuric ester hydrolase activity
CI104_RS08500	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CI104_RS08515	COG1376	ErfK ybiS ycfS ynhG family protein
CI104_RS08520	COG0488	(ABC) transporter
CI104_RS08540	COG0561	phosphatase activity
CI104_RS08545	COG1882	Formate acetyltransferase
CI104_RS08550	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CI104_RS08555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CI104_RS08560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CI104_RS08565	COG0303	'Molybdopterin
CI104_RS08570	COG1446	asparaginase
CI104_RS08580	COG0747	negative chemotaxis
CI104_RS08605	COG2133	pyrroloquinoline quinone binding
CI104_RS08615	COG0625	glutathione transferase activity
CI104_RS08620	COG1686	Belongs to the peptidase S11 family
CI104_RS08625	COG1349	DNA-binding transcription factor activity
CI104_RS08630	COG0671	phosphoesterase, PA-phosphatase related
CI104_RS08635	COG2814	Major facilitator Superfamily
CI104_RS08640	COG0561	phosphatase activity
CI104_RS08645	COG0738	Major facilitator superfamily
CI104_RS08650	COG3226	Transcriptional regulator
CI104_RS08710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CI104_RS08715	COG3842	ATPase activity
CI104_RS08720	COG1176	ABC-type spermidine putrescine transport system, permease component I
CI104_RS08725	COG1177	transmembrane transport
CI104_RS08740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI104_RS08745	COG4160	amino acid transport
CI104_RS08750	COG4215	(ABC) transporter
CI104_RS08755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI104_RS08760	COG1126	abc transporter atp-binding protein
CI104_RS08775	COG3023	N-Acetylmuramoyl-L-alanine amidase
CI104_RS08780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CI104_RS08785	COG0702	epimerase
CI104_RS08790	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CI104_RS08795	COG0028	Belongs to the TPP enzyme family
CI104_RS08805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CI104_RS08815	COG2431	L-lysine efflux transmembrane transporter activity
CI104_RS08825	COG3593	DNA synthesis involved in DNA repair
CI104_RS08830	COG2990	Protein conserved in bacteria
CI104_RS08835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI104_RS08845	COG1278	Cold shock
CI104_RS08855	COG0542	response to heat
CI104_RS08895	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CI104_RS08900	COG4988	ABC transporter
CI104_RS08905	COG0492	ferredoxin-NADP+ reductase activity
CI104_RS08930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CI104_RS08940	COG0243	molybdopterin cofactor binding
CI104_RS08945	COG0437	4 iron, 4 sulfur cluster binding
CI104_RS08950	COG3302	dmso reductase anchor subunit
CI104_RS08955	COG1335	isochorismatase
CI104_RS08970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS08975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CI104_RS08995	COG1737	Transcriptional regulator
CI104_RS09000	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CI104_RS09005	COG1882	Formate acetyltransferase
CI104_RS09010	COG2116	formate transmembrane transporter activity
CI104_RS09015	COG1944	ATP diphosphatase activity
CI104_RS09020	COG2323	membrane
CI104_RS09045	COG0539	negative regulation of cytoplasmic translation
CI104_RS09050	COG0776	regulation of translation
CI104_RS09055	COG0658	competence protein
CI104_RS09055	COG2333	competence protein COMEC
CI104_RS09070	COG3214	Protein conserved in bacteria
CI104_RS09085	COG3173	Aminoglycoside phosphotransferase
CI104_RS09090	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CI104_RS09110	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CI104_RS09120	COG2989	Protein conserved in bacteria
CI104_RS09125	COG3108	Peptidase M15
CI104_RS09130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CI104_RS09135	COG1448	Aminotransferase
CI104_RS09160	COG0308	aminopeptidase N
CI104_RS09170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CI104_RS09180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CI104_RS09185	COG0431	NADPH-dependent FMN reductase
CI104_RS09200	COG0633	Ferredoxin
CI104_RS09200	COG3217	Mosc domain protein beta barrel domain protein
CI104_RS09210	COG0488	(ABC) transporter
CI104_RS09215	COG2995	paraquat-inducible protein a
CI104_RS09220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CI104_RS09220	COG3008	intermembrane lipid transfer
CI104_RS09225	COG3009	Protein conserved in bacteria
CI104_RS09230	COG3130	regulation of translation
CI104_RS09240	COG1067	ATP-dependent peptidase activity
CI104_RS09260	COG3070	regulator of competence-specific genes
CI104_RS09265	COG1289	transmembrane transporter activity
CI104_RS09270	COG3304	Inner membrane component domain
CI104_RS09275	COG0210	DNA helicase
CI104_RS09290	COG1832	CoA-binding protein
CI104_RS09310	COG2920	part of a sulfur-relay system
CI104_RS09315	COG0670	Belongs to the BI1 family
CI104_RS09335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CI104_RS09440	COG1403	HNH endonuclease
CI104_RS09460	COG3179	chitinase
CI104_RS09510	COG0616	signal peptide processing
CI104_RS09550	COG4386	tail sheath protein
CI104_RS09610	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CI104_RS09620	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CI104_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS09655	COG1733	regulation of RNA biosynthetic process
CI104_RS09660	COG3468	outer membrane autotransporter barrel domain protein
CI104_RS09685	COG2885	chlorophyll binding
CI104_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS09795	COG2378	regulation of single-species biofilm formation
CI104_RS09800	COG2610	gluconate transmembrane transporter activity
CI104_RS09805	COG0129	dihydroxy-acid dehydratase activity
CI104_RS09810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CI104_RS09815	COG1414	Transcriptional regulator
CI104_RS09840	COG0159	tryptophan synthase activity
CI104_RS09850	COG3153	acetyltransferase
CI104_RS09855	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CI104_RS09875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS09875	COG3711	transcriptional antiterminator
CI104_RS09880	COG3711	transcriptional antiterminator
CI104_RS09900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CI104_RS09905	COG1454	alcohol dehydrogenase
CI104_RS09920	COG0667	Aldo Keto reductase
CI104_RS09925	COG4948	Mandelate Racemase Muconate Lactonizing
CI104_RS09930	COG1064	alcohol dehydrogenase
CI104_RS09935	COG1869	D-ribose catabolic process
CI104_RS09940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS09945	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CI104_RS09950	COG0456	acetyltransferase
CI104_RS09965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CI104_RS09970	COG0156	8-amino-7-oxononanoate synthase activity
CI104_RS09980	COG0795	lipopolysaccharide-transporting ATPase activity
CI104_RS09985	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CI104_RS09995	COG2244	polysaccharide biosynthetic process
CI104_RS10000	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CI104_RS10005	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CI104_RS10010	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CI104_RS10020	COG1414	Transcriptional regulator
CI104_RS10025	COG0800	Aldolase
CI104_RS10030	COG2271	Major facilitator Superfamily
CI104_RS10050	COG0628	permease
CI104_RS10055	COG0348	domain, Protein
CI104_RS10075	COG4232	protein-disulfide reductase activity
CI104_RS10080	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CI104_RS10080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CI104_RS10085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CI104_RS10090	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CI104_RS10095	COG0672	)-iron permease
CI104_RS10110	COG1136	(ABC) transporter
CI104_RS10110	COG0577	efflux transmembrane transporter activity
CI104_RS10120	COG0577	efflux transmembrane transporter activity
CI104_RS10120	COG1136	(ABC) transporter
CI104_RS10140	COG0640	Transcriptional regulator
CI104_RS10160	COG3729	General stress protein
CI104_RS10165	COG1309	transcriptional regulator
CI104_RS10175	COG0506	proline dehydrogenase activity
CI104_RS10175	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CI104_RS10175	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CI104_RS10185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CI104_RS10205	COG1702	phosphate starvation-inducible protein PhoH
CI104_RS10225	COG3381	protein complex oligomerization
CI104_RS10275	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CI104_RS10280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CI104_RS10305	COG5645	(Lipo)protein
CI104_RS10325	COG1560	Kdo2-lipid A biosynthetic process
CI104_RS10340	COG3038	cytochrome b561
CI104_RS10375	COG2999	glutathione oxidoreductase activity
CI104_RS10385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CI104_RS10400	COG0728	peptidoglycan biosynthetic process
CI104_RS10430	COG1558	bacterial-type flagellum-dependent cell motility
CI104_RS10445	COG4787	bacterial-type flagellum-dependent cell motility
CI104_RS10450	COG4786	Flagellar basal body rod
CI104_RS10470	COG1256	bacterial-type flagellum assembly
CI104_RS10475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CI104_RS10480	COG2814	Major facilitator Superfamily
CI104_RS10485	COG0583	DNA-binding transcription factor activity
CI104_RS10490	COG1530	ribonuclease E activity
CI104_RS10500	COG0564	pseudouridine synthase activity
CI104_RS10510	COG1399	metal-binding, possibly nucleic acid-binding protein
CI104_RS10535	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS10545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CI104_RS10550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CI104_RS10555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CI104_RS10565	COG0470	DNA polymerase III
CI104_RS10570	COG0084	hydrolase, TatD family'
CI104_RS10580	COG4773	Receptor
CI104_RS10585	COG0537	adenosine 5'-monophosphoramidase activity
CI104_RS10590	COG5633	Lipoprotein
CI104_RS10600	COG0510	thiamine kinase activity
CI104_RS10615	COG1252	NADH dehydrogenase
CI104_RS10620	COG3134	Outer membrane lipoprotein
CI104_RS10675	COG3267	Type II secretory pathway component ExeA
CI104_RS10675	COG3409	Peptidoglycan-binding domain 1 protein
CI104_RS10745	COG4373	Mu-like prophage FluMu protein gp28
CI104_RS10755	COG2369	cell adhesion
CI104_RS10870	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CI104_RS10890	COG1309	transcriptional regulator
CI104_RS10900	COG1376	ErfK ybiS ycfS ynhG family protein
CI104_RS10900	COG1388	LysM domain
CI104_RS10905	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CI104_RS10910	COG4763	Acyl-transferase
CI104_RS10915	COG4591	ABC-type transport system involved in lipoprotein release permease component
CI104_RS10920	COG1136	(ABC) transporter
CI104_RS10925	COG4591	ABC-type transport system involved in lipoprotein release permease component
CI104_RS10935	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CI104_RS10970	COG2850	peptidyl-arginine hydroxylation
CI104_RS10975	COG2205	protein histidine kinase activity
CI104_RS10985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CI104_RS11005	COG1187	pseudouridine synthase activity
CI104_RS11010	COG0538	isocitrate dehydrogenase activity
CI104_RS11015	COG0582	viral genome integration into host DNA
CI104_RS11065	COG1802	Transcriptional regulator
CI104_RS11065	COG4626	Terminase
CI104_RS11070	COG4725	Belongs to the MT-A70-like family
CI104_RS11080	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CI104_RS11100	COG1403	HNH endonuclease
CI104_RS11125	COG3772	lysozyme
CI104_RS11145	COG4220	transposase activity
CI104_RS11165	COG1030	water channel activity
CI104_RS11180	COG0582	viral genome integration into host DNA
CI104_RS11245	COG4220	transposase activity
CI104_RS11305	COG1196	nuclear chromosome segregation
CI104_RS11375	COG0538	isocitrate dehydrogenase activity
CI104_RS11395	COG3121	Chaperone
CI104_RS11400	COG3188	usher protein
CI104_RS11415	COG1396	sequence-specific DNA binding
CI104_RS11430	COG0789	Transcriptional regulator
CI104_RS11435	COG2200	EAL domain
CI104_RS11470	COG2226	methyltransferase
CI104_RS11480	COG3729	General stress protein
CI104_RS11485	COG3685	Protein conserved in bacteria
CI104_RS11490	COG1546	Belongs to the CinA family
CI104_RS11495	COG2323	membrane
CI104_RS11505	COG3111	PFAM Bacterial OB fold (BOF) protein
CI104_RS11510	COG1278	Cold shock
CI104_RS11530	COG3383	formate dehydrogenase (NAD+) activity
CI104_RS11535	COG2261	transglycosylase associated protein
CI104_RS11555	COG3189	MarR family transcriptional regulator
CI104_RS11560	COG1683	Conserved Protein
CI104_RS11565	COG0504	CTP synthase activity
CI104_RS11570	COG2807	transmembrane transport
CI104_RS11575	COG2207	Transcriptional regulator
CI104_RS11590	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CI104_RS11595	COG2199	diguanylate cyclase activity
CI104_RS11605	COG2766	serine protein kinase
CI104_RS11610	COG3713	MltA-interacting MipA family protein
CI104_RS11615	COG0656	L-ascorbic acid biosynthetic process
CI104_RS11635	COG3139	Protein of unknown function (DUF1315)
CI104_RS11650	COG1063	alcohol dehydrogenase
CI104_RS11655	COG2271	Major facilitator Superfamily
CI104_RS11660	COG1063	alcohol dehydrogenase
CI104_RS11665	COG0191	fructose-bisphosphate aldolase activity
CI104_RS11670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS11675	COG0667	Aldo Keto reductase
CI104_RS11680	COG1349	DNA-binding transcription factor activity
CI104_RS11685	COG2814	Major facilitator Superfamily
CI104_RS11690	COG1335	isochorismatase
CI104_RS11695	COG0252	asparaginase activity
CI104_RS11700	COG0616	signal peptide processing
CI104_RS11705	COG0778	Nitroreductase
CI104_RS11715	COG0709	Synthesizes selenophosphate from selenide and ATP
CI104_RS11720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CI104_RS11735	COG0494	nUDIX hydrolase
CI104_RS11740	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CI104_RS11745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CI104_RS11750	COG2897	thiosulfate sulfurtransferase activity
CI104_RS11755	COG4136	ATPase activity
CI104_RS11760	COG4135	transport system, permease component
CI104_RS11765	COG4134	Bacterial extracellular solute-binding protein
CI104_RS11775	COG0708	Exodeoxyribonuclease III
CI104_RS11805	COG3678	ATP-independent chaperone mediated protein folding
CI104_RS11815	COG0322	excinuclease ABC activity
CI104_RS11825	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CI104_RS11835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI104_RS11840	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI104_RS11845	COG1447	Phosphotransferase system cellobiose-specific component IIA
CI104_RS11850	COG2169	Transcriptional regulator
CI104_RS11850	COG1917	Cupin 2, conserved barrel domain protein
CI104_RS11855	COG1486	melibiose metabolic process
CI104_RS11865	COG0753	catalase activity
CI104_RS11875	COG1823	symporter activity
CI104_RS11880	COG1988	membrane-bound metal-dependent
CI104_RS11885	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS11890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CI104_RS11900	COG3001	Fructosamine kinase
CI104_RS11910	COG1105	Belongs to the carbohydrate kinase PfkB family
CI104_RS11915	COG3137	Salt-induced outer membrane protein
CI104_RS11960	COG0072	phenylalanine-tRNA ligase activity
CI104_RS11960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CI104_RS11975	COG0386	Belongs to the glutathione peroxidase family
CI104_RS11985	COG0791	NLP P60 protein
CI104_RS12000	COG4256	Hemin uptake protein
CI104_RS12005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CI104_RS12015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CI104_RS12015	COG0574	Belongs to the PEP-utilizing enzyme family
CI104_RS12020	COG0318	PFAM AMP-dependent synthetase and ligase
CI104_RS12025	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CI104_RS12030	COG0644	oxidoreductase
CI104_RS12035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CI104_RS12040	COG2086	electron transfer activity
CI104_RS12045	COG1917	Cupin 2, conserved barrel domain protein
CI104_RS12045	COG2207	Transcriptional regulator
CI104_RS12050	COG1960	acyl-CoA dehydrogenase activity
CI104_RS12055	COG4670	ketone body catabolic process
CI104_RS12070	COG2271	Major facilitator Superfamily
CI104_RS12075	COG0738	Major facilitator superfamily
CI104_RS12100	COG0628	permease
CI104_RS12105	COG0247	lactate metabolic process
CI104_RS12105	COG0277	FAD linked oxidase domain protein
CI104_RS12110	COG2050	protein possibly involved in aromatic compounds catabolism
CI104_RS12130	COG0316	Belongs to the HesB IscA family
CI104_RS12135	COG0719	Fe-S assembly protein
CI104_RS12140	COG0396	ATPase activity
CI104_RS12145	COG0719	Fe-S assembly protein
CI104_RS12160	COG1376	ErfK ybiS ycfS ynhG family protein
CI104_RS12185	COG2011	ABC-type metal ion transport system permease component
CI104_RS12190	COG1464	Belongs to the NlpA lipoprotein family
CI104_RS12235	COG0437	4 iron, 4 sulfur cluster binding
CI104_RS12240	COG2414	aldehyde ferredoxin oxidoreductase
CI104_RS12250	COG0437	4 iron, 4 sulfur cluster binding
CI104_RS12255	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CI104_RS12265	COG0765	amino acid transport
CI104_RS12270	COG0765	amino acid transport
CI104_RS12280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI104_RS12295	COG4529	Protein conserved in bacteria
CI104_RS12300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CI104_RS12335	COG0307	riboflavin synthase, alpha
CI104_RS12340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CI104_RS12345	COG2814	Major facilitator Superfamily
CI104_RS12350	COG0583	DNA-binding transcription factor activity
CI104_RS12370	COG2814	Major facilitator Superfamily
CI104_RS12380	COG0791	NLP P60 protein
CI104_RS12385	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CI104_RS12390	COG1201	RNA secondary structure unwinding
CI104_RS12400	COG0346	lactoylglutathione lyase activity
CI104_RS12405	COG1902	pentaerythritol trinitrate reductase activity
CI104_RS12410	COG1309	transcriptional regulator
CI104_RS12415	COG3313	Fe-S protein
CI104_RS12420	COG4989	oxidoreductase activity
CI104_RS12430	COG1289	transmembrane transporter activity
CI104_RS12435	COG1566	PFAM secretion protein HlyD family protein
CI104_RS12460	COG3895	Periplasmic Protein
CI104_RS12470	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CI104_RS12475	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CI104_RS12480	COG0625	glutathione transferase activity
CI104_RS12490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CI104_RS12500	COG4659	FMN binding
CI104_RS12540	COG0673	inositol 2-dehydrogenase activity
CI104_RS12550	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CI104_RS12555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI104_RS12555	COG1263	PTS System
CI104_RS12560	COG1609	Transcriptional regulator
CI104_RS12565	COG5339	Protein conserved in bacteria
CI104_RS12570	COG1482	cell wall glycoprotein biosynthetic process
CI104_RS12575	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CI104_RS12575	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CI104_RS12580	COG0114	fumarate hydratase activity
CI104_RS12590	COG2205	protein histidine kinase activity
CI104_RS12595	COG0745	RESPONSE REGULATOR receiver
CI104_RS12600	COG3136	membrane protein required for alginate biosynthesis
CI104_RS12610	COG0531	amino acid
CI104_RS12620	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CI104_RS12625	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CI104_RS12630	COG0628	permease
CI104_RS12650	COG3591	Belongs to the peptidase S1B family
CI104_RS12660	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CI104_RS12665	COG2814	Major facilitator Superfamily
CI104_RS12670	COG0583	DNA-binding transcription factor activity
CI104_RS12675	COG1940	carbohydrate kinase activity
CI104_RS12680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CI104_RS12710	COG3302	dmso reductase anchor subunit
CI104_RS12715	COG0437	4 iron, 4 sulfur cluster binding
CI104_RS12720	COG0243	molybdopterin cofactor binding
CI104_RS12740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CI104_RS12755	COG1063	alcohol dehydrogenase
CI104_RS12760	COG0477	Major facilitator Superfamily
CI104_RS12775	COG0246	Mannitol dehydrogenase
CI104_RS12785	COG1802	Transcriptional regulator
CI104_RS12790	COG4221	oxidoreductase activity
CI104_RS12795	COG0339	signal peptide processing
CI104_RS12820	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CI104_RS12860	COG2814	Major facilitator Superfamily
CI104_RS12865	COG0697	spore germination
CI104_RS12880	COG1846	Transcriptional regulator
CI104_RS12895	COG0583	DNA-binding transcription factor activity
CI104_RS12900	COG1012	belongs to the aldehyde dehydrogenase family
CI104_RS12905	COG0840	transmembrane signaling receptor activity
CI104_RS12910	COG2066	Belongs to the glutaminase family
CI104_RS12920	COG2199	diguanylate cyclase activity
CI104_RS12935	COG3781	membrane
CI104_RS12975	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS12980	COG2271	Major facilitator Superfamily
CI104_RS12985	COG1063	alcohol dehydrogenase
CI104_RS13000	COG1396	sequence-specific DNA binding
CI104_RS13005	COG3550	peptidyl-serine autophosphorylation
CI104_RS13020	COG2801	Transposase and inactivated derivatives
CI104_RS13025	COG1649	PFAM Uncharacterised BCR, COG1649
CI104_RS13050	COG3706	GGDEF domain
CI104_RS13055	COG2199	diguanylate cyclase activity
CI104_RS13055	COG2202	Pas domain
CI104_RS13055	COG2200	EAL domain
CI104_RS13060	COG0840	transmembrane signaling receptor activity
CI104_RS13075	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CI104_RS13080	COG0747	negative chemotaxis
CI104_RS13085	COG0601	transmembrane transport
CI104_RS13090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CI104_RS13095	COG0444	Belongs to the ABC transporter superfamily
CI104_RS13100	COG4608	Belongs to the ABC transporter superfamily
CI104_RS13105	COG1764	response to oxidative stress
CI104_RS13120	COG0488	(ABC) transporter
CI104_RS13130	COG3093	addiction module antidote protein HigA
CI104_RS13135	COG2864	formate dehydrogenase
CI104_RS13140	COG0437	4 iron, 4 sulfur cluster binding
CI104_RS13195	COG3485	protocatechuate 3,4-dioxygenase
CI104_RS13200	COG4829	muconolactone delta-isomerase
CI104_RS13205	COG4948	Mandelate Racemase Muconate Lactonizing
CI104_RS13210	COG1414	Transcriptional regulator
CI104_RS13220	COG2223	nitrite transmembrane transporter activity
CI104_RS13225	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CI104_RS13230	COG1140	nitrate reductase beta subunit
CI104_RS13235	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CI104_RS13240	COG2181	nitrate reductase activity
CI104_RS13245	COG0384	phenazine biosynthesis protein PhzF
CI104_RS13255	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CI104_RS13260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CI104_RS13275	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CI104_RS13285	COG1609	Transcriptional regulator
CI104_RS13295	COG2271	Major facilitator Superfamily
CI104_RS13300	COG0625	glutathione transferase activity
CI104_RS13305	COG0840	transmembrane signaling receptor activity
CI104_RS13320	COG4772	TonB-dependent receptor
CI104_RS13325	COG1802	Transcriptional regulator
CI104_RS13330	COG2130	NADP-dependent
CI104_RS13340	COG1247	-acetyltransferase
CI104_RS13345	COG3238	Protein conserved in bacteria
CI104_RS13355	COG0747	negative chemotaxis
CI104_RS13395	COG1177	transmembrane transport
CI104_RS13400	COG1176	ABC-type spermidine putrescine transport system, permease component I
CI104_RS13405	COG3842	ATPase activity
CI104_RS13410	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CI104_RS13415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CI104_RS13420	COG1598	PFAM Uncharacterised protein family UPF0150
CI104_RS13425	COG1724	mRNA binding
CI104_RS13430	COG1271	oxidase subunit
CI104_RS13435	COG1294	oxidase, subunit
CI104_RS13445	COG0826	peptidase U32
CI104_RS13450	COG1396	sequence-specific DNA binding
CI104_RS13455	COG3135	benzoate transporter
CI104_RS13465	COG0697	spore germination
CI104_RS13475	COG0500	methyltransferase
CI104_RS13480	COG1275	C4-dicarboxylate transporter malic acid transport protein
CI104_RS13485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CI104_RS13490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CI104_RS13495	COG1363	Peptidase, m42
CI104_RS13500	COG3414	Phosphotransferase system galactitol-specific IIB component
CI104_RS13505	COG3775	system Galactitol-specific IIC component
CI104_RS13510	COG0434	BtpA family
CI104_RS13515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS13520	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CI104_RS13525	COG1349	DNA-binding transcription factor activity
CI104_RS13530	COG2841	Protein conserved in bacteria
CI104_RS13540	COG2272	Belongs to the type-B carboxylesterase lipase family
CI104_RS13545	COG5383	Protein conserved in bacteria
CI104_RS13550	COG3485	protocatechuate 3,4-dioxygenase
CI104_RS13555	COG3485	protocatechuate 3,4-dioxygenase
CI104_RS13560	COG1227	inorganic diphosphatase activity
CI104_RS13565	COG0583	DNA-binding transcription factor activity
CI104_RS13570	COG0840	transmembrane signaling receptor activity
CI104_RS13595	COG3038	cytochrome b561
CI104_RS13600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CI104_RS13605	COG1012	belongs to the aldehyde dehydrogenase family
CI104_RS13610	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CI104_RS13635	COG1643	Atp-dependent helicase
CI104_RS13650	COG0667	Aldo Keto reductase
CI104_RS13655	COG3784	Protein of unknown function (DUF1318)
CI104_RS13665	COG2911	Protein conserved in bacteria
CI104_RS13680	COG3121	Chaperone
CI104_RS13705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CI104_RS13710	COG3187	Heat shock protein
CI104_RS13715	COG3042	response to heat
CI104_RS13720	COG0791	NLP P60 protein
CI104_RS13725	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CI104_RS13725	COG1013	pyruvate-flavodoxin oxidoreductase activity
CI104_RS13725	COG0674	pyruvate-flavodoxin oxidoreductase activity
CI104_RS13725	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CI104_RS13730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CI104_RS13750	COG0513	Belongs to the DEAD box helicase family
CI104_RS13765	COG0840	transmembrane signaling receptor activity
CI104_RS13780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CI104_RS13785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CI104_RS13795	COG0183	Belongs to the thiolase family
CI104_RS13800	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CI104_RS13810	COG1414	Transcriptional regulator
CI104_RS13815	COG2840	Smr protein MutS2
CI104_RS13820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CI104_RS13835	COG3182	Iron-regulated membrane protein
CI104_RS13840	COG0668	transmembrane transport
CI104_RS13845	COG0346	lactoylglutathione lyase activity
CI104_RS13850	COG1349	DNA-binding transcription factor activity
CI104_RS13855	COG4166	transmembrane transport
CI104_RS13860	COG2866	Carboxypeptidase
CI104_RS13865	COG4948	Mandelate Racemase Muconate Lactonizing
CI104_RS13885	COG3106	COG3106 Predicted ATPase
CI104_RS13895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI104_RS13900	COG1120	ATPase activity
CI104_RS13915	COG1609	Transcriptional regulator
CI104_RS13925	COG3842	ATPase activity
CI104_RS13930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CI104_RS13935	COG1554	hydrolase, family 65, central catalytic
CI104_RS13940	COG0673	inositol 2-dehydrogenase activity
CI104_RS13945	COG1082	Xylose isomerase domain protein TIM barrel
CI104_RS13950	COG1063	alcohol dehydrogenase
CI104_RS13955	COG0395	ABC-type sugar transport system, permease component
CI104_RS13960	COG1175	transmembrane transport
CI104_RS13965	COG1653	transport
CI104_RS13970	COG0366	Alpha amylase catalytic
CI104_RS13980	COG1983	PspC domain protein
CI104_RS13990	COG1842	Phage shock protein A
CI104_RS13995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CI104_RS14010	COG4171	peptide transport system, permease
CI104_RS14020	COG4172	Belongs to the ABC transporter superfamily
CI104_RS14025	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CI104_RS14030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CI104_RS14030	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CI104_RS14040	COG5001	Diguanylate cyclase
CI104_RS14050	COG1349	DNA-binding transcription factor activity
CI104_RS14060	COG0023	Translation Initiation Factor
CI104_RS14070	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CI104_RS14075	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CI104_RS14080	COG0671	phosphoesterase, PA-phosphatase related
CI104_RS14100	COG0583	DNA-binding transcription factor activity
CI104_RS14115	COG0616	signal peptide processing
CI104_RS14120	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS14130	COG1187	pseudouridine synthase activity
CI104_RS14150	COG2801	Transposase and inactivated derivatives
CI104_RS14160	COG0009	L-threonylcarbamoyladenylate synthase
CI104_RS14175	COG0512	Glutamine amidotransferase of anthranilate synthase
CI104_RS14175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CI104_RS14195	COG3706	GGDEF domain
CI104_RS14200	COG3047	cAMP biosynthetic process
CI104_RS14235	COG2350	Protein conserved in bacteria
CI104_RS14255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CI104_RS14265	COG0444	Belongs to the ABC transporter superfamily
CI104_RS14290	COG2095	MarC family integral membrane protein
CI104_RS14295	COG1454	alcohol dehydrogenase
CI104_RS14295	COG1012	belongs to the aldehyde dehydrogenase family
CI104_RS14300	COG1435	thymidine kinase activity
CI104_RS14310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CI104_RS14315	COG0745	RESPONSE REGULATOR receiver
CI104_RS14320	COG1752	Esterase of the alpha-beta hydrolase superfamily
CI104_RS14330	COG0788	formyltetrahydrofolate deformylase activity
CI104_RS14345	COG2181	nitrate reductase activity
CI104_RS14350	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CI104_RS14355	COG1140	nitrate reductase beta subunit
CI104_RS14360	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CI104_RS14365	COG2223	nitrite transmembrane transporter activity
CI104_RS14375	COG3850	Histidine kinase
CI104_RS14380	COG2197	response regulator
CI104_RS14385	COG4932	domain protein
CI104_RS14390	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CI104_RS14400	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CI104_RS14405	COG4572	Cation transport regulator
CI104_RS14410	COG0387	Pfam Sodium calcium exchanger
CI104_RS14430	COG2890	protein-(glutamine-N5) methyltransferase activity
CI104_RS14465	COG0659	secondary active sulfate transmembrane transporter activity
CI104_RS14475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CI104_RS14480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI104_RS14485	COG1120	ATPase activity
CI104_RS14495	COG0723	plastoquinol--plastocyanin reductase activity
CI104_RS14500	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CI104_RS14500	COG2857	Cytochrome c1
CI104_RS14520	COG0012	GTP binding
CI104_RS14525	COG0840	transmembrane signaling receptor activity
CI104_RS14540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI104_RS14550	COG2188	Transcriptional regulator
CI104_RS14555	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CI104_RS14575	COG2376	Dihydroxyacetone kinase
CI104_RS14580	COG1461	Dihydroxyacetone kinase
CI104_RS14585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CI104_RS14585	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CI104_RS14585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS14595	COG4774	siderophore transport
CI104_RS14605	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CI104_RS14615	COG1619	proteins homologs of microcin C7 resistance protein MccF
CI104_RS14625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CI104_RS14635	COG2719	SpoVR family
CI104_RS14660	COG0179	Fumarylacetoacetate (FAA) hydrolase
CI104_RS14675	COG2894	cell division
CI104_RS14690	COG3443	Belongs to the bacterial solute-binding protein 9 family
CI104_RS14715	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CI104_RS14745	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CI104_RS14750	COG5301	cellulose 1,4-beta-cellobiosidase activity
CI104_RS14755	COG3778	Protein conserved in bacteria
CI104_RS14760	COG3299	homolog of phage Mu protein gp47
CI104_RS14790	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
CI104_RS14800	COG4386	tail sheath protein
CI104_RS14830	COG4397	Mu-like prophage major head subunit gpT
CI104_RS14850	COG4373	Mu-like prophage FluMu protein gp28
CI104_RS14870	COG0640	Transcriptional regulator
CI104_RS14910	COG5566	PFAM Mor transcription activator
CI104_RS14930	COG4396	Host-nuclease inhibitor protein Gam
CI104_RS14945	COG2842	Transposition protein
CI104_RS14950	COG2801	Transposase and inactivated derivatives
CI104_RS14980	COG0251	oxidation-reduction process
CI104_RS14990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CI104_RS15000	COG0698	ribose 5-phosphate isomerase
CI104_RS15005	COG2084	Dehydrogenase
CI104_RS15010	COG0765	amino acid transport
CI104_RS15015	COG0765	amino acid transport
CI104_RS15040	COG3615	Tellurite resistance protein tehB
CI104_RS15050	COG0583	DNA-binding transcription factor activity
CI104_RS15055	COG0473	3-isopropylmalate dehydrogenase activity
CI104_RS15060	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CI104_RS15065	COG0318	PFAM AMP-dependent synthetase and ligase
CI104_RS15070	COG3065	identical protein binding
CI104_RS15075	COG1214	PFAM Peptidase M22, glycoprotease
CI104_RS15080	COG1199	ATP-dependent helicase activity
CI104_RS15085	COG0251	oxidation-reduction process
CI104_RS15095	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CI104_RS15105	COG1760	l-serine dehydratase
CI104_RS15110	COG2200	EAL domain
CI104_RS15115	COG1253	flavin adenine dinucleotide binding
CI104_RS15125	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS15125	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI104_RS15130	COG3715	PTS system
CI104_RS15135	COG3716	PTS system mannose fructose sorbose family IID component
CI104_RS15155	COG2226	methyltransferase
CI104_RS15160	COG0768	penicillin binding
CI104_RS15195	COG1414	Transcriptional regulator
CI104_RS15200	COG2814	Major facilitator Superfamily
CI104_RS15220	COG1956	GAF domain-containing protein
CI104_RS15225	COG2995	paraquat-inducible protein a
CI104_RS15230	COG3008	intermembrane lipid transfer
CI104_RS15250	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CI104_RS15260	COG1276	copper resistance
CI104_RS15265	COG2372	response to copper ion
CI104_RS15275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CI104_RS15280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CI104_RS15285	COG1770	oligopeptidase
CI104_RS15290	COG2979	Protein of unknown function (DUF533)
CI104_RS15300	COG3141	response to X-ray
CI104_RS15310	COG0800	Aldolase
CI104_RS15315	COG0129	dihydroxy-acid dehydratase activity
CI104_RS15320	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CI104_RS15325	COG1737	Transcriptional regulator
CI104_RS15335	COG1560	Kdo2-lipid A biosynthetic process
CI104_RS15340	COG0739	heme binding
CI104_RS15345	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CI104_RS15355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CI104_RS15375	COG0217	transcriptional regulatory protein
CI104_RS15380	COG0494	nUDIX hydrolase
CI104_RS15390	COG1335	isochorismatase
CI104_RS15395	COG1801	Protein of unknown function DUF72
CI104_RS15400	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CI104_RS15420	COG3102	Protein conserved in bacteria
CI104_RS15430	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CI104_RS15460	COG3121	Chaperone
CI104_RS15465	COG3188	usher protein
CI104_RS15470	COG3539	Fimbrial protein
CI104_RS15480	COG0745	RESPONSE REGULATOR receiver
CI104_RS15495	COG0840	transmembrane signaling receptor activity
CI104_RS15530	COG1301	dicarboxylic acid transport
CI104_RS15575	COG1877	trehalose-phosphatase activity
CI104_RS15580	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI104_RS15585	COG1129	ABC transporter
CI104_RS15590	COG1879	ABC-type sugar transport system periplasmic component
CI104_RS15605	COG1528	Iron-storage protein
CI104_RS15620	COG0477	Major facilitator Superfamily
CI104_RS15635	COG1528	Iron-storage protein
CI104_RS15645	COG0814	amino acid
CI104_RS15650	COG3012	SEC-C Motif Domain Protein
CI104_RS15650	COG3318	Belongs to the UPF0149 family
CI104_RS15675	COG2207	Transcriptional regulator
CI104_RS15700	COG3713	MltA-interacting MipA family protein
CI104_RS15750	COG0322	excinuclease ABC activity
CI104_RS15755	COG2197	response regulator
CI104_RS15765	COG2197	response regulator
CI104_RS15770	COG1126	abc transporter atp-binding protein
CI104_RS15775	COG0765	amino acid transport
CI104_RS15785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI104_RS15820	COG0366	Alpha amylase catalytic
CI104_RS15835	COG0425	Belongs to the sulfur carrier protein TusA family
CI104_RS15850	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CI104_RS15860	COG1157	protein secretion by the type III secretion system
CI104_RS15875	COG1580	Controls the rotational direction of flagella during chemotaxis
CI104_RS15895	COG1338	Plays a role in the flagellum-specific transport system
CI104_RS15900	COG1987	bacterial-type flagellum assembly
CI104_RS15910	COG2197	response regulator
CI104_RS15935	COG5475	Uncharacterized small protein (DUF2158)
CI104_RS15940	COG2354	Protein conserved in bacteria
CI104_RS15945	COG0697	spore germination
CI104_RS15950	COG3727	T/G mismatch-specific endonuclease activity
CI104_RS15955	COG0270	DNA (cytosine-5-)-methyltransferase activity
CI104_RS15960	COG1418	mRNA catabolic process
CI104_RS15970	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CI104_RS15975	COG3468	outer membrane autotransporter barrel domain protein
CI104_RS15995	COG0583	DNA-binding transcription factor activity
CI104_RS16010	COG0477	Major facilitator Superfamily
CI104_RS16015	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CI104_RS16020	COG1074	ATP-dependent DNA helicase activity
CI104_RS16060	COG0534	Mate efflux family protein
CI104_RS16070	COG1376	ErfK ybiS ycfS ynhG family protein
CI104_RS16225	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CI104_RS16240	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CI104_RS16260	COG4656	Part of a membrane complex involved in electron transport
CI104_RS16280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CI104_RS16295	COG1289	transmembrane transporter activity
CI104_RS16300	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CI104_RS16310	COG2925	Exonuclease
CI104_RS16315	COG0425	Belongs to the sulfur carrier protein TusA family
CI104_RS16320	COG2391	methyltransferase activity
CI104_RS16325	COG0531	amino acid
CI104_RS16330	COG0583	DNA-binding transcription factor activity
CI104_RS16335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CI104_RS16405	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CI104_RS16420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CI104_RS16440	COG1086	Polysaccharide biosynthesis protein
CI104_RS16475	COG2327	Polysaccharide pyruvyl transferase
CI104_RS16480	COG2244	polysaccharide biosynthetic process
CI104_RS16485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CI104_RS16490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CI104_RS16500	COG0297	glycogen (starch) synthase activity
CI104_RS16505	COG1051	belongs to the nudix hydrolase family
CI104_RS16510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CI104_RS16515	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CI104_RS16520	COG0110	maltose O-acetyltransferase activity
CI104_RS16525	COG1216	Glycosyl transferase, family 2
CI104_RS16535	COG0438	transferase activity, transferring glycosyl groups
CI104_RS16540	COG1045	serine acetyltransferase
CI104_RS16545	COG0463	Glycosyl transferase, family 2
CI104_RS16570	COG1253	flavin adenine dinucleotide binding
CI104_RS16575	COG2982	Protein involved in outer membrane biogenesis
CI104_RS16590	COG3447	MASE1 domain protein
CI104_RS16590	COG5001	Diguanylate cyclase
CI104_RS16590	COG5002	protein histidine kinase activity
CI104_RS16595	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CI104_RS16600	COG0443	Heat shock 70 kDa protein
CI104_RS16625	COG2205	protein histidine kinase activity
CI104_RS16630	COG0745	RESPONSE REGULATOR receiver
CI104_RS16635	COG0826	peptidase U32
CI104_RS16645	COG1830	Aldolase
CI104_RS16655	COG2211	Major facilitator Superfamily
CI104_RS16660	COG1397	ADP-ribosylglycohydrolase
CI104_RS16665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS16670	COG2188	Transcriptional regulator
CI104_RS16675	COG0351	phosphomethylpyrimidine kinase
CI104_RS16695	COG5455	response to cobalt ion
CI104_RS16710	COG4808	Protein conserved in bacteria
CI104_RS16715	COG4807	Protein conserved in bacteria
CI104_RS16725	COG3275	phosphorelay sensor kinase activity
CI104_RS16730	COG0789	Transcriptional regulator
CI104_RS16740	COG1174	glycine betaine transport
CI104_RS16745	COG1125	glycine betaine transport
CI104_RS16750	COG1174	glycine betaine transport
CI104_RS16755	COG1732	Glycine betaine
CI104_RS16760	COG1472	Belongs to the glycosyl hydrolase 3 family
CI104_RS16765	COG0277	FAD linked oxidase domain protein
CI104_RS16775	COG1686	Belongs to the peptidase S11 family
CI104_RS16790	COG0586	Pfam SNARE associated Golgi protein
CI104_RS16800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CI104_RS16805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CI104_RS16810	COG0625	glutathione transferase activity
CI104_RS16825	COG2271	Major facilitator Superfamily
CI104_RS16840	COG1346	cytolysis
CI104_RS16850	COG2949	membrane
CI104_RS16865	COG1129	ABC transporter
CI104_RS16870	COG1879	ABC-type sugar transport system periplasmic component
CI104_RS16885	COG2311	Membrane
CI104_RS16905	COG4771	TonB-dependent receptor
CI104_RS16910	COG0833	amino acid
CI104_RS16920	COG0583	DNA-binding transcription factor activity
CI104_RS16925	COG2855	membrane
CI104_RS16935	COG1522	sequence-specific DNA binding
CI104_RS16935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS16940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CI104_RS16945	COG2313	pseudouridylate synthase activity
CI104_RS16950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS16955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CI104_RS16955	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CI104_RS16955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CI104_RS16960	COG1105	Belongs to the carbohydrate kinase PfkB family
CI104_RS16990	COG0246	Mannitol dehydrogenase
CI104_RS16995	COG0523	cobalamin synthesis protein
CI104_RS17000	COG0671	phosphoesterase, PA-phosphatase related
CI104_RS17010	COG0791	NLP P60 protein
CI104_RS17015	COG2200	EAL domain
CI104_RS17020	COG4166	transmembrane transport
CI104_RS17025	COG4174	ABC transporter (Permease)
CI104_RS17030	COG4239	(ABC) transporter, permease
CI104_RS17035	COG4172	Belongs to the ABC transporter superfamily
CI104_RS17050	COG2814	Major facilitator Superfamily
CI104_RS17055	COG1187	pseudouridine synthase activity
CI104_RS17060	COG1061	Type III restriction enzyme res subunit
CI104_RS17080	COG3083	sulfuric ester hydrolase activity
CI104_RS17090	COG2246	polysaccharide biosynthetic process
CI104_RS17105	COG2197	response regulator
CI104_RS17110	COG3088	subunit of a heme lyase
CI104_RS17110	COG4235	cytochrome complex assembly
CI104_RS17115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CI104_RS17120	COG1138	Cytochrome C-type biogenesis protein
CI104_RS17130	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CI104_RS17135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CI104_RS17140	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CI104_RS17145	COG4133	protoheme IX ABC transporter activity
CI104_RS17150	COG3005	denitrification pathway
CI104_RS17155	COG3043	anaerobic respiration
CI104_RS17160	COG0348	domain, Protein
CI104_RS17165	COG0437	4 iron, 4 sulfur cluster binding
CI104_RS17175	COG3062	negative regulation of establishment of protein localization
CI104_RS17180	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI104_RS17180	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI104_RS17195	COG0659	secondary active sulfate transmembrane transporter activity
CI104_RS17200	COG2239	Acts as a magnesium transporter
CI104_RS17205	COG4615	Cyclic peptide transporter
CI104_RS17210	COG3145	DNA-N1-methyladenine dioxygenase activity
CI104_RS17215	COG2169	Transcriptional regulator
CI104_RS17215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CI104_RS17220	COG1477	protein flavinylation
CI104_RS17230	COG0642	Histidine kinase
CI104_RS17230	COG2198	Histidine kinase
CI104_RS17235	COG2197	response regulator
CI104_RS17245	COG3852	Histidine kinase
CI104_RS17250	COG2204	response regulator
CI104_RS17255	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CI104_RS17260	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CI104_RS17265	COG2031	fatty acid transporter
CI104_RS17270	COG0183	Belongs to the thiolase family
CI104_RS17280	COG0673	inositol 2-dehydrogenase activity
CI104_RS17285	COG3732	PTS system glucitol sorbitol-specific
CI104_RS17295	COG3730	PTS system glucitol sorbitol-specific
CI104_RS17320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CI104_RS17325	COG3642	lipopolysaccharide core region biosynthetic process
CI104_RS17330	COG0584	glycerophosphoryl diester phosphodiesterase
CI104_RS17335	COG2271	Major facilitator Superfamily
CI104_RS17340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CI104_RS17350	COG0247	lactate metabolic process
CI104_RS17355	COG5464	transposase or invertase
CI104_RS17365	COG2271	Major facilitator Superfamily
CI104_RS17375	COG1414	Transcriptional regulator
CI104_RS17440	COG0318	PFAM AMP-dependent synthetase and ligase
CI104_RS17465	COG1169	isochorismate synthase
CI104_RS17470	COG4575	ribosome binding
CI104_RS17475	COG2153	protein acetylation
CI104_RS17485	COG0835	chemotaxis
CI104_RS17485	COG0784	Response regulator, receiver
CI104_RS17495	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CI104_RS17500	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CI104_RS17510	COG0839	Belongs to the complex I subunit 6 family
CI104_RS17520	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CI104_RS17535	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CI104_RS17555	COG0583	DNA-binding transcription factor activity
CI104_RS17560	COG0436	Aminotransferase
CI104_RS17570	COG0490	domain, Protein
CI104_RS17570	COG0471	metal ion transport
CI104_RS17575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CI104_RS17600	COG1288	antiporter activity
CI104_RS17605	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CI104_RS17610	COG3959	Transketolase, thiamine diphosphate binding domain
CI104_RS17615	COG3037	sugar-specific permease SgaT UlaA
CI104_RS17625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS17630	COG1609	Transcriptional regulator
CI104_RS17640	COG0622	Phosphoesterase
CI104_RS17645	COG0625	glutathione transferase activity
CI104_RS17650	COG0625	glutathione transferase activity
CI104_RS17655	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CI104_RS17660	COG1090	epimerase
CI104_RS17665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CI104_RS17670	COG4598	ABC transporter
CI104_RS17685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI104_RS17700	COG0163	prenyltransferase activity
CI104_RS17705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CI104_RS17710	COG1286	toxin biosynthetic process
CI104_RS17715	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CI104_RS17720	COG0285	dihydrofolate synthase activity
CI104_RS17730	COG0586	Pfam SNARE associated Golgi protein
CI104_RS17740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CI104_RS17780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CI104_RS17795	COG3101	peptidyl-lysine hydroxylation
CI104_RS17800	COG0730	response to heat
CI104_RS17825	COG2062	phosphohistidine phosphatase, SixA
CI104_RS17840	COG3691	Protein conserved in bacteria
CI104_RS17845	COG2067	long-chain fatty acid transport protein
CI104_RS17855	COG2116	formate transmembrane transporter activity
CI104_RS17880	COG0412	Dienelactone hydrolase
CI104_RS17895	COG1126	abc transporter atp-binding protein
CI104_RS17900	COG0765	amino acid transport
CI104_RS17910	COG0583	DNA-binding transcription factor activity
CI104_RS17915	COG0288	reversible hydration of carbon dioxide
CI104_RS17925	COG0590	tRNA wobble adenosine to inosine editing
CI104_RS17930	COG2807	transmembrane transport
CI104_RS17940	COG1560	Kdo2-lipid A biosynthetic process
CI104_RS17945	COG0436	Aminotransferase
CI104_RS17950	COG3275	phosphorelay sensor kinase activity
CI104_RS17955	COG3279	Response regulator of the LytR AlgR family
CI104_RS17970	COG3122	Protein conserved in bacteria
CI104_RS17990	COG3961	Belongs to the TPP enzyme family
CI104_RS17995	COG0667	Aldo Keto reductase
CI104_RS18010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CI104_RS18015	COG2199	diguanylate cyclase activity
CI104_RS18015	COG2200	EAL domain
CI104_RS18030	COG3415	Transposase
CI104_RS18035	COG3415	Transposase
CI104_RS18070	COG0583	DNA-binding transcription factor activity
CI104_RS18075	COG2211	Major facilitator Superfamily
CI104_RS18080	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CI104_RS18090	COG0583	DNA-binding transcription factor activity
CI104_RS18095	COG0385	Bile acid
CI104_RS18100	COG3530	Putative quorum-sensing-regulated virulence factor
CI104_RS18130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS18170	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CI104_RS18175	COG4208	sulfate ABC transporter
CI104_RS18180	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CI104_RS18185	COG4150	thiosulfate binding
CI104_RS18190	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS18195	COG2837	iron assimilation
CI104_RS18215	COG0860	N-Acetylmuramoyl-L-alanine amidase
CI104_RS18290	COG4812	Cobalamin adenosyltransferase
CI104_RS18325	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CI104_RS18330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CI104_RS18335	COG5342	invasion associated locus B
CI104_RS18345	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI104_RS18345	COG0493	'glutamate synthase
CI104_RS18350	COG3850	Histidine kinase
CI104_RS18355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CI104_RS18360	COG1393	Belongs to the ArsC family
CI104_RS18375	COG0400	carboxylic ester hydrolase activity
CI104_RS18385	COG2321	neutral zinc metallopeptidase
CI104_RS18395	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CI104_RS18405	COG2716	regulation of RNA biosynthetic process
CI104_RS18410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CI104_RS18415	COG0628	permease
CI104_RS18420	COG4783	chaperone-mediated protein folding
CI104_RS18425	COG1393	Belongs to the ArsC family
CI104_RS18435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI104_RS18440	COG1446	asparaginase
CI104_RS18455	COG2233	PERMEase
CI104_RS18465	COG2723	6-phospho-beta-galactosidase activity
CI104_RS18470	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CI104_RS18475	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CI104_RS18480	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CI104_RS18490	COG2200	EAL domain
CI104_RS18505	COG0516	GMP reductase activity
CI104_RS18505	COG0517	IMP dehydrogenase activity
CI104_RS18515	COG1645	bacterial-type flagellum-dependent swarming motility
CI104_RS18535	COG2976	Protein conserved in bacteria
CI104_RS18565	COG4953	penicillin-binding protein 1C
CI104_RS18570	COG2373	Large extracellular alpha-helical protein
CI104_RS18575	COG2897	thiosulfate sulfurtransferase activity
CI104_RS18590	COG2975	iron-sulfur cluster assembly
CI104_RS18595	COG0633	Ferredoxin
CI104_RS18615	COG0822	iron-sulfur transferase activity
CI104_RS18640	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CI104_RS18645	COG3683	transport system, periplasmic component
CI104_RS18655	COG1129	ABC transporter
CI104_RS18660	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI104_RS18670	COG1069	ribulokinase activity
CI104_RS18675	COG0517	IMP dehydrogenase activity
CI104_RS18675	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CI104_RS18680	COG3711	transcriptional antiterminator
CI104_RS18685	COG2814	Major facilitator Superfamily
CI104_RS18695	COG0477	Major facilitator Superfamily
CI104_RS18695	COG2814	Major facilitator Superfamily
CI104_RS18700	COG0457	Tetratricopeptide repeat
CI104_RS18705	COG1940	carbohydrate kinase activity
CI104_RS18710	COG2259	Doxx family
CI104_RS18730	COG0347	Belongs to the P(II) protein family
CI104_RS18735	COG2204	response regulator
CI104_RS18740	COG3170	Tfp pilus assembly protein FimV
CI104_RS18745	COG2205	protein histidine kinase activity
CI104_RS18770	COG0560	Phosphoserine phosphatase
CI104_RS18775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI104_RS18775	COG1263	PTS System
CI104_RS18780	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CI104_RS18785	COG1737	Transcriptional regulator
CI104_RS18790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI104_RS18800	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CI104_RS18825	COG0681	Belongs to the peptidase S26 family
CI104_RS18835	COG3086	response to oxidative stress
CI104_RS18840	COG3026	antisigma factor binding
CI104_RS18845	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CI104_RS18855	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CI104_RS18865	COG0513	Belongs to the DEAD box helicase family
CI104_RS18880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CI104_RS18890	COG3118	belongs to the thioredoxin family
CI104_RS18895	COG3148	PFAM DTW domain containing protein
CI104_RS18900	COG0045	succinate-CoA ligase (ADP-forming) activity
CI104_RS18900	COG1042	CoA-binding domain protein
CI104_RS18900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CI104_RS18905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CI104_RS18910	COG5544	Lipoprotein
CI104_RS18915	COG0477	Major facilitator Superfamily
CI104_RS18940	COG0542	response to heat
CI104_RS18960	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CI104_RS18965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CI104_RS18970	COG0077	Prephenate dehydratase
CI104_RS18970	COG1605	Chorismate mutase
CI104_RS18975	COG1605	Chorismate mutase
CI104_RS18975	COG0287	Prephenate dehydrogenase
CI104_RS18980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CI104_RS18995	COG2199	diguanylate cyclase activity
CI104_RS19000	COG2885	chlorophyll binding
CI104_RS19035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CI104_RS19040	COG4137	Cytochrome C assembly protein
CI104_RS19045	COG4536	flavin adenine dinucleotide binding
CI104_RS19065	COG0497	DNA recombination
CI104_RS19070	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CI104_RS19080	COG2867	negative regulation of translational initiation
CI104_RS19180	COG0235	Class ii aldolase
CI104_RS19190	COG2084	Dehydrogenase
CI104_RS19200	COG1349	DNA-binding transcription factor activity
CI104_RS19240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI104_RS19250	COG0582	viral genome integration into host DNA
CI104_RS19275	COG4983	Phage plasmid primase, P4 family domain protein
CI104_RS19320	COG3596	GTP binding
CI104_RS19325	COG2378	regulation of single-species biofilm formation
CI104_RS19350	COG2003	Belongs to the UPF0758 family
CI104_RS19370	COG0471	metal ion transport
CI104_RS19385	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CI104_RS19405	COG3052	prosthetic group binding
CI104_RS19415	COG0179	Fumarylacetoacetate (FAA) hydrolase
CI104_RS19420	COG2814	Major facilitator Superfamily
CI104_RS19425	COG2828	Protein conserved in bacteria
CI104_RS19430	COG0583	DNA-binding transcription factor activity
CI104_RS19455	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CI104_RS19460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CI104_RS19465	COG2200	EAL domain
CI104_RS19490	COG0579	oxidoreductase
CI104_RS19495	COG1012	belongs to the aldehyde dehydrogenase family
CI104_RS19500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CI104_RS19505	COG1113	amino acid transport
CI104_RS19510	COG1802	Transcriptional regulator
CI104_RS19515	COG1652	LysM domain
CI104_RS19520	COG0401	homolog of Blt101
CI104_RS19525	COG0640	Transcriptional regulator
CI104_RS19530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CI104_RS19550	COG4575	ribosome binding
CI104_RS19560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CI104_RS19595	COG4176	ABC-type proline glycine betaine transport system permease component
CI104_RS19605	COG2814	Major facilitator Superfamily
CI104_RS19610	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CI104_RS19620	COG1846	Transcriptional regulator
CI104_RS19625	COG1566	PFAM secretion protein HlyD family protein
CI104_RS19630	COG2814	Major facilitator Superfamily
CI104_RS19645	COG1238	metal cluster binding
CI104_RS19650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CI104_RS19685	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CI104_RS19705	COG1546	Belongs to the CinA family
CI104_RS19710	COG2951	lytic endotransglycosylase activity
CI104_RS19715	COG3730	PTS system glucitol sorbitol-specific
CI104_RS19720	COG3732	PTS system glucitol sorbitol-specific
CI104_RS19730	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS19735	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS19740	COG1349	DNA-binding transcription factor activity
CI104_RS19745	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CI104_RS19745	COG0517	IMP dehydrogenase activity
CI104_RS19765	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CI104_RS19770	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI104_RS19775	COG1609	Transcriptional regulator
CI104_RS19780	COG1263	PTS System
CI104_RS19780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI104_RS19785	COG2723	6-phospho-beta-galactosidase activity
CI104_RS19795	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CI104_RS19805	COG3260	NADH ubiquinone oxidoreductase 20
CI104_RS19810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CI104_RS19815	COG3261	NADH dehydrogenase
CI104_RS19815	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CI104_RS19820	COG0650	Formate hydrogenlyase subunit 4
CI104_RS19825	COG0651	ATP synthesis coupled electron transport
CI104_RS19830	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI104_RS19840	COG0375	protein maturation
CI104_RS19845	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CI104_RS19850	COG0298	carbon dioxide binding
CI104_RS19855	COG0409	Hydrogenase expression formation protein
CI104_RS19860	COG0309	Hydrogenase expression formation protein (HypE)
CI104_RS19880	COG1121	(ABC) transporter
CI104_RS19885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CI104_RS19890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CI104_RS19905	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CI104_RS19910	COG0163	prenyltransferase activity
CI104_RS19920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CI104_RS19925	COG1388	LysM domain
CI104_RS19925	COG4942	peptidase
CI104_RS19980	COG2234	aminopeptidase activity
CI104_RS20010	COG0720	synthase
CI104_RS20015	COG0602	queuosine metabolic process
CI104_RS20020	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CI104_RS20025	COG2190	(PTS) system
CI104_RS20025	COG1263	PTS System
CI104_RS20025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI104_RS20030	COG1737	Transcriptional regulator
CI104_RS20045	COG3956	TIGRFAM MazG family protein
CI104_RS20050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CI104_RS20060	COG4999	Histidine kinase
CI104_RS20060	COG3850	Histidine kinase
CI104_RS20060	COG2205	protein histidine kinase activity
CI104_RS20060	COG3437	response regulator, receiver
CI104_RS20065	COG1929	Belongs to the glycerate kinase type-1 family
CI104_RS20070	COG4948	Mandelate Racemase Muconate Lactonizing
CI104_RS20075	COG4948	Mandelate Racemase Muconate Lactonizing
CI104_RS20080	COG2271	Major facilitator Superfamily
CI104_RS20090	COG0716	FMN binding
CI104_RS20095	COG0564	pseudouridine synthase activity
CI104_RS20100	COG3098	single-species biofilm formation
CI104_RS20115	COG1611	Belongs to the LOG family
CI104_RS20120	COG0814	amino acid
CI104_RS20125	COG1760	l-serine dehydratase
CI104_RS20135	COG0235	Class ii aldolase
CI104_RS20150	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI104_RS20155	COG1129	ABC transporter
CI104_RS20175	COG1349	DNA-binding transcription factor activity
CI104_RS20230	COG0745	RESPONSE REGULATOR receiver
CI104_RS20245	COG2363	Small membrane protein
CI104_RS20250	COG0583	DNA-binding transcription factor activity
CI104_RS20260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CI104_RS20265	COG2166	iron-sulfur cluster assembly
CI104_RS20270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CI104_RS20275	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CI104_RS20295	COG0860	N-Acetylmuramoyl-L-alanine amidase
CI104_RS20305	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CI104_RS20305	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CI104_RS20310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CI104_RS20315	COG1074	ATP-dependent DNA helicase activity
CI104_RS20320	COG1025	Belongs to the peptidase M16 family
CI104_RS20325	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CI104_RS20330	COG4967	type IV pilus modification protein PilV
CI104_RS20340	COG4795	General secretion pathway protein
CI104_RS20345	COG2165	general secretion pathway protein
CI104_RS20360	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CI104_RS20380	COG0861	Integral membrane protein TerC family
CI104_RS20390	COG0667	Aldo Keto reductase
CI104_RS20420	COG1609	Transcriptional regulator
CI104_RS20430	COG0583	DNA-binding transcription factor activity
CI104_RS20435	COG1794	racemase activity, acting on amino acids and derivatives
CI104_RS20445	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS20455	COG0183	Belongs to the thiolase family
CI104_RS20470	COG0814	amino acid
CI104_RS20485	COG2771	luxR family
CI104_RS20510	COG3121	Chaperone
CI104_RS20515	COG3188	usher protein
CI104_RS20530	COG0402	S-adenosylhomocysteine deaminase activity
CI104_RS20535	COG0549	Belongs to the carbamate kinase family
CI104_RS20540	COG1304	FMN binding
CI104_RS20545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CI104_RS20555	COG0666	response to abiotic stimulus
CI104_RS20575	COG2388	GCN5-related N-acetyl-transferase
CI104_RS20580	COG3592	Divergent 4Fe-4S mono-cluster
CI104_RS20585	COG3710	Transcriptional regulator
CI104_RS20605	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CI104_RS20615	COG0582	viral genome integration into host DNA
CI104_RS20620	COG4974	Belongs to the 'phage' integrase family
CI104_RS20630	COG3539	Fimbrial protein
CI104_RS20635	COG3121	Chaperone
CI104_RS20640	COG3188	usher protein
CI104_RS20645	COG3539	Fimbrial protein
CI104_RS20650	COG3539	Fimbrial protein
CI104_RS20655	COG3539	Fimbrial protein
CI104_RS20675	COG2329	Antibiotic biosynthesis monooxygenase
CI104_RS20680	COG0583	DNA-binding transcription factor activity
CI104_RS20685	COG1027	Aspartate ammonia-lyase
CI104_RS20690	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CI104_RS20705	COG3121	Chaperone
CI104_RS20720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI104_RS20720	COG2205	protein histidine kinase activity
CI104_RS20720	COG2198	Histidine kinase
CI104_RS20720	COG0784	Response regulator, receiver
CI104_RS20725	COG2197	response regulator
CI104_RS20730	COG3366	ferrous iron transmembrane transporter activity
CI104_RS20735	COG0700	Nucleoside recognition
CI104_RS20740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CI104_RS20745	COG0583	DNA-binding transcription factor activity
CI104_RS20760	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CI104_RS20765	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS20775	COG1609	Transcriptional regulator
CI104_RS20780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CI104_RS20800	COG0444	Belongs to the ABC transporter superfamily
CI104_RS20810	COG0601	transmembrane transport
CI104_RS20815	COG0747	negative chemotaxis
CI104_RS20825	COG1116	anion transmembrane transporter activity
CI104_RS20830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CI104_RS20835	COG4521	taurine ABC transporter
CI104_RS20840	COG1794	racemase activity, acting on amino acids and derivatives
CI104_RS20845	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CI104_RS20850	COG1393	Belongs to the ArsC family
CI104_RS20855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CI104_RS20880	COG4942	peptidase
CI104_RS20885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CI104_RS20890	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CI104_RS20895	COG2080	2 iron, 2 sulfur cluster binding
CI104_RS20900	COG3829	transcription factor binding
CI104_RS20905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CI104_RS20910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CI104_RS20915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CI104_RS20925	COG0549	Belongs to the carbamate kinase family
CI104_RS20930	COG3608	succinylglutamate desuccinylase aspartoacylase
CI104_RS20930	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CI104_RS20935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CI104_RS20940	COG2068	MobA-Related Protein
CI104_RS20945	COG0493	'glutamate synthase
CI104_RS20945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI104_RS20950	COG0402	S-adenosylhomocysteine deaminase activity
CI104_RS20955	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CI104_RS20960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CI104_RS20960	COG2080	2 iron, 2 sulfur cluster binding
CI104_RS20965	COG2233	PERMEase
CI104_RS20970	COG0402	S-adenosylhomocysteine deaminase activity
CI104_RS20975	COG2252	PERMEase
CI104_RS20980	COG2233	PERMEase
CI104_RS21005	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CI104_RS21015	COG4974	Belongs to the 'phage' integrase family
CI104_RS21030	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CI104_RS21040	COG1272	protein, Hemolysin III
CI104_RS21050	COG1737	Transcriptional regulator
CI104_RS21055	COG2723	6-phospho-beta-galactosidase activity
CI104_RS21060	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS21080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CI104_RS21085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CI104_RS21090	COG0006	proline dipeptidase activity
CI104_RS21115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CI104_RS21120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CI104_RS21150	COG0560	Phosphoserine phosphatase
CI104_RS21155	COG3726	membrane protein affecting hemolysin expression
CI104_RS21185	COG1328	CTP reductase activity
CI104_RS21190	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CI104_RS21195	COG0084	hydrolase, TatD family'
CI104_RS21200	COG4667	esterase of the alpha-beta hydrolase superfamily
CI104_RS21205	COG5487	UPF0391 membrane protein
CI104_RS21210	COG2823	Periplasmic or secreted lipoprotein
CI104_RS21220	COG1011	Hydrolase
CI104_RS21225	COG0456	acetyltransferase
CI104_RS21230	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CI104_RS21265	COG4114	ferric iron reductase
CI104_RS21270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI104_RS21275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CI104_RS21280	COG2197	response regulator
CI104_RS21285	COG2197	response regulator
CI104_RS21305	COG2966	Psort location CytoplasmicMembrane, score
CI104_RS21320	COG1484	DNA-dependent DNA replication
CI104_RS21330	COG1368	sulfuric ester hydrolase activity
CI104_RS21335	COG1063	alcohol dehydrogenase
CI104_RS21340	COG1802	Transcriptional regulator
CI104_RS21345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CI104_RS21355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CI104_RS21365	COG0840	transmembrane signaling receptor activity
CI104_RS21375	COG1966	Carbon starvation protein
CI104_RS21380	COG2879	small protein
CI104_RS21385	COG0523	cobalamin synthesis protein
CI104_RS21400	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CI104_RS21425	COG1566	PFAM secretion protein HlyD family protein
CI104_RS21435	COG5457	Domain of unknown function (DUF1127)
CI104_RS21440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CI104_RS21450	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS21460	COG2271	Major facilitator Superfamily
CI104_RS21465	COG4948	Mandelate Racemase Muconate Lactonizing
CI104_RS21475	COG4948	Mandelate Racemase Muconate Lactonizing
CI104_RS21485	COG2186	Transcriptional regulator
CI104_RS21490	COG0129	dihydroxy-acid dehydratase activity
CI104_RS21495	COG0445	tRNA wobble uridine modification
CI104_RS21500	COG2084	Dehydrogenase
CI104_RS21510	COG2271	Major facilitator Superfamily
CI104_RS21515	COG2721	sulfolactate sulfo-lyase activity
CI104_RS21530	COG2814	Major facilitator Superfamily
CI104_RS21535	COG0626	cystathionine gamma-synthase activity
CI104_RS21540	COG1301	dicarboxylic acid transport
CI104_RS21545	COG0583	DNA-binding transcription factor activity
CI104_RS21550	COG2733	membrane
CI104_RS21560	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CI104_RS21565	COG1924	4 iron, 4 sulfur cluster binding
CI104_RS21575	COG3204	pilus organization
CI104_RS21580	COG0477	Major facilitator Superfamily
CI104_RS21635	COG2271	Major facilitator Superfamily
CI104_RS21640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CI104_RS21645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CI104_RS21655	COG1414	Transcriptional regulator
CI104_RS21660	COG3507	Belongs to the glycosyl hydrolase 43 family
CI104_RS21665	COG2211	Major facilitator Superfamily
CI104_RS21670	COG0129	dihydroxy-acid dehydratase activity
CI104_RS21745	COG2003	Belongs to the UPF0758 family
CI104_RS21770	COG2378	regulation of single-species biofilm formation
CI104_RS21775	COG3596	GTP binding
CI104_RS21815	COG0159	tryptophan synthase activity
CI104_RS21825	COG3655	Transcriptional regulator
CI104_RS21840	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CI104_RS21860	COG0720	synthase
CI104_RS21865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CI104_RS21870	COG0514	ATP-dependent DNA helicase (RecQ)
CI104_RS21890	COG0514	ATP-dependent DNA helicase (RecQ)
CI104_RS21925	COG0582	viral genome integration into host DNA
CI104_RS21935	COG1064	alcohol dehydrogenase
CI104_RS21940	COG3265	gluconokinase activity
CI104_RS21945	COG1063	alcohol dehydrogenase
CI104_RS21950	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS21955	COG2610	gluconate transmembrane transporter activity
CI104_RS21960	COG1609	Transcriptional regulator
CI104_RS21965	COG0433	COG0433 Predicted ATPase
CI104_RS21970	COG0795	lipopolysaccharide-transporting ATPase activity
CI104_RS21975	COG0795	lipopolysaccharide-transporting ATPase activity
CI104_RS21990	COG2927	DNA polymerase III (CHI subunit)
CI104_RS21995	COG0525	valine-tRNA ligase activity
CI104_RS22030	COG0243	molybdopterin cofactor binding
CI104_RS22035	COG3005	denitrification pathway
CI104_RS22040	COG2731	YhcH YjgK YiaL family protein
CI104_RS22045	COG2235	arginine
CI104_RS22060	COG3457	Alanine racemase
CI104_RS22070	COG1438	arginine binding
CI104_RS22110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CI104_RS22125	COG1263	PTS System
CI104_RS22125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI104_RS22130	COG0366	Alpha amylase catalytic
CI104_RS22140	COG0602	queuosine metabolic process
CI104_RS22145	COG3711	transcriptional antiterminator
CI104_RS22145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS22160	COG3964	amidohydrolase
CI104_RS22210	COG3783	Cytochrome b(562)
CI104_RS22215	COG0312	modulator of DNA gyrase
CI104_RS22235	COG0840	transmembrane signaling receptor activity
CI104_RS22260	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI104_RS22265	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI104_RS22270	COG1129	ABC transporter
CI104_RS22275	COG1879	ABC-type sugar transport system periplasmic component
CI104_RS22285	COG2105	PFAM AIG2 family protein
CI104_RS22290	COG2911	Protein conserved in bacteria
CI104_RS22295	COG0729	surface antigen
CI104_RS22305	COG1609	Transcriptional regulator
CI104_RS22310	COG0673	inositol 2-dehydrogenase activity
CI104_RS22315	COG0673	inositol 2-dehydrogenase activity
CI104_RS22335	COG1253	flavin adenine dinucleotide binding
CI104_RS22350	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CI104_RS22355	COG1218	3'(2'),5'-bisphosphate nucleotidase
CI104_RS22365	COG1733	regulation of RNA biosynthetic process
CI104_RS22370	COG0702	epimerase
CI104_RS22380	COG0697	spore germination
CI104_RS22390	COG1113	amino acid transport
CI104_RS22395	COG0545	Peptidyl-prolyl cis-trans isomerase
CI104_RS22400	COG3061	Opacity-associated protein A
CI104_RS22415	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CI104_RS22420	COG2965	DNA replication, synthesis of RNA primer
CI104_RS22430	COG0730	response to heat
CI104_RS22475	COG1073	alpha beta
CI104_RS22480	COG3650	response to hydrogen peroxide
CI104_RS22490	COG1960	acyl-CoA dehydrogenase activity
CI104_RS22495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CI104_RS22500	COG0557	exoribonuclease II activity
CI104_RS22515	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CI104_RS22520	COG0330	HflC and HflK could
CI104_RS22525	COG0330	HflC and HflK could
CI104_RS22530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CI104_RS22550	COG0860	N-Acetylmuramoyl-L-alanine amidase
CI104_RS22555	COG0802	atpase or kinase
CI104_RS22560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CI104_RS22560	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CI104_RS22565	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CI104_RS22600	COG3264	Mechanosensitive ion channel
CI104_RS22600	COG1511	domain protein
CI104_RS22615	COG1053	succinate dehydrogenase
CI104_RS22620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CI104_RS22640	COG2076	Multidrug Resistance protein
CI104_RS22650	COG5510	response to toxic substance
CI104_RS22665	COG1509	lysine 2,3-aminomutase activity
CI104_RS22695	COG0531	amino acid
CI104_RS22700	COG3030	protein affecting phage T7 exclusion by the F plasmid
CI104_RS22705	COG1027	Aspartate ammonia-lyase
CI104_RS22710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CI104_RS22725	COG1309	transcriptional regulator
CI104_RS22765	COG3539	Fimbrial protein
CI104_RS22780	COG3121	Chaperone
CI104_RS22785	COG3188	usher protein
CI104_RS22825	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS22840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CI104_RS22850	COG0577	efflux transmembrane transporter activity
CI104_RS22850	COG1136	(ABC) transporter
CI104_RS22855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI104_RS22860	COG1132	(ABC) transporter
CI104_RS22885	COG3539	Fimbrial protein
CI104_RS22890	COG3539	Fimbrial protein
CI104_RS22900	COG3121	Chaperone
CI104_RS22905	COG3188	usher protein
CI104_RS22915	COG3539	Fimbrial protein
CI104_RS22920	COG2221	Nitrite and sulphite reductase 4Fe-4S
CI104_RS22920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI104_RS22925	COG3381	protein complex oligomerization
CI104_RS22930	COG3302	dmso reductase anchor subunit
CI104_RS22935	COG0437	4 iron, 4 sulfur cluster binding
CI104_RS22940	COG0243	molybdopterin cofactor binding
CI104_RS22945	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CI104_RS22950	COG3290	protein histidine kinase activity
CI104_RS22955	COG4565	transcriptional regulatory protein
CI104_RS22960	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CI104_RS22965	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CI104_RS22965	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CI104_RS22970	COG3647	Membrane
CI104_RS22980	COG2211	Major facilitator Superfamily
CI104_RS22990	COG2169	Transcriptional regulator
CI104_RS22995	COG1982	Orn Lys Arg decarboxylase major
CI104_RS23005	COG2207	Transcriptional regulator
CI104_RS23010	COG0531	amino acid
CI104_RS23015	COG2194	sulfuric ester hydrolase activity
CI104_RS23020	COG0745	RESPONSE REGULATOR receiver
CI104_RS23055	COG2824	Alkylphosphonate utilization operon protein PhnA
CI104_RS23060	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CI104_RS23065	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CI104_RS23070	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CI104_RS23075	COG3639	organic phosphonate transmembrane transporter activity
CI104_RS23080	COG2188	Transcriptional regulator
CI104_RS23085	COG3624	Phosphonate C-P lyase system protein PhnG
CI104_RS23090	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CI104_RS23095	COG3626	phosphonate metabolism
CI104_RS23100	COG3627	carbon phosphorus lyase activity
CI104_RS23105	COG4107	phosphonate C-P lyase system protein PhnK
CI104_RS23110	COG4778	phosphonate C-P lyase system protein PhnL
CI104_RS23115	COG3454	Phosphonate metabolism
CI104_RS23120	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CI104_RS23125	COG0456	acetyltransferase
CI104_RS23130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CI104_RS23145	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CI104_RS23150	COG1301	dicarboxylic acid transport
CI104_RS23160	COG4235	cytochrome complex assembly
CI104_RS23165	COG3088	subunit of a heme lyase
CI104_RS23170	COG1138	Cytochrome C-type biogenesis protein
CI104_RS23175	COG3301	Polysulphide reductase, NrfD
CI104_RS23180	COG0437	4 iron, 4 sulfur cluster binding
CI104_RS23185	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CI104_RS23195	COG2801	Transposase and inactivated derivatives
CI104_RS23220	COG3162	membrane
CI104_RS23230	COG1346	cytolysis
CI104_RS23235	COG1380	Effector of murein hydrolase LrgA
CI104_RS23240	COG0583	DNA-binding transcription factor activity
CI104_RS23245	COG0025	NhaP-type Na H and K H
CI104_RS23255	COG2252	PERMEase
CI104_RS23280	COG0789	Transcriptional regulator
CI104_RS23290	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CI104_RS23300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CI104_RS23310	COG0629	single-stranded DNA binding
CI104_RS23320	COG2315	Protein conserved in bacteria
CI104_RS23325	COG3700	Belongs to the class B bacterial acid phosphatase family
CI104_RS23330	COG1448	Aminotransferase
CI104_RS23335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CI104_RS23340	COG0305	Participates in initiation and elongation during chromosome replication
CI104_RS23355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CI104_RS23365	COG0735	belongs to the Fur family
CI104_RS23370	COG3237	CsbD-like
CI104_RS23375	COG0534	Mate efflux family protein
CI104_RS23385	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CI104_RS23435	COG3833	ABC-type maltose transport systems, permease component
CI104_RS23445	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CI104_RS23470	COG0527	aspartate kinase activity
CI104_RS23475	COG3541	Predicted nucleotidyltransferase
CI104_RS23480	COG1690	Belongs to the RtcB family
CI104_RS23495	COG4650	regulator
CI104_RS23515	COG0561	phosphatase activity
CI104_RS23520	COG1349	DNA-binding transcription factor activity
CI104_RS23530	COG1187	pseudouridine synthase activity
CI104_RS23570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CI104_RS23575	COG1028	Short-chain dehydrogenase reductase Sdr
CI104_RS23620	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CI104_RS23630	COG0456	acetyltransferase
CI104_RS23660	COG0151	Belongs to the GarS family
CI104_RS23670	COG4191	Histidine kinase
CI104_RS23695	COG1515	deoxyribonuclease V activity
CI104_RS23725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CI104_RS23730	COG2104	thiamine diphosphate biosynthetic process
CI104_RS23745	COG3706	GGDEF domain
CI104_RS23755	COG1447	Phosphotransferase system cellobiose-specific component IIA
CI104_RS23795	COG0250	Participates in transcription elongation, termination and antitermination
CI104_RS23800	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CI104_RS23850	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CI104_RS23885	COG4206	TonB-dependent receptor
CI104_RS23890	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CI104_RS23900	COG1309	transcriptional regulator
CI104_RS23910	COG0583	DNA-binding transcription factor activity
CI104_RS23915	COG1070	Carbohydrate kinase
CI104_RS23920	COG3623	hexulose-6-phosphate isomerase
CI104_RS23925	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI104_RS23930	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI104_RS23945	COG1349	DNA-binding transcription factor activity
CI104_RS23950	COG0235	Class ii aldolase
CI104_RS23970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CI104_RS23980	COG2194	sulfuric ester hydrolase activity
CI104_RS23985	COG2207	Transcriptional regulator
CI104_RS23990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CI104_RS23995	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CI104_RS24000	COG1882	Formate acetyltransferase
CI104_RS24005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CI104_RS24010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CI104_RS24015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS24015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CI104_RS24015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI104_RS24025	COG0371	Dehydrogenase
CI104_RS24030	COG0697	spore germination
CI104_RS24045	COG0583	DNA-binding transcription factor activity
CI104_RS24055	COG0527	aspartate kinase activity
CI104_RS24055	COG0460	homoserine dehydrogenase
CI104_RS24060	COG0626	cystathionine gamma-synthase activity
CI104_RS24075	COG2211	Major facilitator Superfamily
CI104_RS24090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CI104_RS24095	COG1609	Transcriptional regulator
CI104_RS24100	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CI104_RS24115	COG1575	Belongs to the MenA family. Type 1 subfamily
CI104_RS24130	COG3074	FtsZ-dependent cytokinesis
CI104_RS24135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CI104_RS24145	COG1494	fructose-1,6-bisphosphatase
CI104_RS24155	COG3152	Membrane
CI104_RS24170	COG0471	metal ion transport
CI104_RS24180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CI104_RS24190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS24195	COG2211	Major facilitator Superfamily
CI104_RS24205	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CI104_RS24220	COG3678	ATP-independent chaperone mediated protein folding
CI104_RS24225	COG0745	RESPONSE REGULATOR receiver
CI104_RS24230	COG2205	protein histidine kinase activity
CI104_RS24235	COG2258	MOSC domain
CI104_RS24240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CI104_RS24250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CI104_RS24290	COG1129	ABC transporter
CI104_RS24295	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI104_RS24300	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI104_RS24305	COG1454	alcohol dehydrogenase
CI104_RS24325	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CI104_RS24365	COG0205	6-phosphofructokinase activity
CI104_RS24385	COG3383	formate dehydrogenase (NAD+) activity
CI104_RS24385	COG0243	molybdopterin cofactor binding
CI104_RS24390	COG0243	molybdopterin cofactor binding
CI104_RS24390	COG3383	formate dehydrogenase (NAD+) activity
CI104_RS24395	COG0437	4 iron, 4 sulfur cluster binding
CI104_RS24400	COG2864	formate dehydrogenase
CI104_RS24405	COG2304	oxidoreductase activity
CI104_RS24410	COG5002	protein histidine kinase activity
CI104_RS24415	COG0745	RESPONSE REGULATOR receiver
CI104_RS24430	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CI104_RS24435	COG0657	acetylesterase activity
CI104_RS24440	COG0456	acetyltransferase
CI104_RS24445	COG1490	D-aminoacyl-tRNA deacylase activity
CI104_RS24455	COG1011	Hydrolase
CI104_RS24465	COG1349	DNA-binding transcription factor activity
CI104_RS24470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS24480	COG3684	Belongs to the aldolase LacD family
CI104_RS24490	COG2017	converts alpha-aldose to the beta-anomer
CI104_RS24500	COG1501	Belongs to the glycosyl hydrolase 31 family
CI104_RS24510	COG2211	Major facilitator Superfamily
CI104_RS24515	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CI104_RS24530	COG0174	glutamine synthetase
CI104_RS24535	COG3852	Histidine kinase
CI104_RS24550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CI104_RS24575	COG0204	Acyl-transferase
CI104_RS24590	COG3084	Protein conserved in bacteria
CI104_RS24595	COG0746	molybdenum cofactor guanylyltransferase activity
CI104_RS24600	COG1763	Mo-molybdopterin cofactor biosynthetic process
CI104_RS24630	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CI104_RS24640	COG1739	Uncharacterized protein family UPF0029
CI104_RS24660	COG0543	2 iron, 2 sulfur cluster binding
CI104_RS24680	COG0805	protein transport
CI104_RS24690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CI104_RS24700	COG3165	ubiquinone biosynthetic process from chorismate
CI104_RS24710	COG1322	Protein conserved in bacteria
CI104_RS24720	COG0412	Dienelactone hydrolase
CI104_RS24730	COG0583	DNA-binding transcription factor activity
CI104_RS24735	COG0697	spore germination
CI104_RS24740	COG0561	phosphatase activity
CI104_RS24745	COG2267	carboxylic ester hydrolase activity
CI104_RS24750	COG1280	lysine exporter protein (LysE YggA)
CI104_RS24755	COG1280	lysine exporter protein (LysE YggA)
CI104_RS24760	COG0514	ATP-dependent DNA helicase (RecQ)
CI104_RS24790	COG1011	Hydrolase
CI104_RS24795	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CI104_RS24810	COG5567	small periplasmic lipoprotein
CI104_RS24835	COG2959	enzyme of heme biosynthesis
CI104_RS24840	COG3071	HemY protein
CI104_RS24885	COG2244	polysaccharide biosynthetic process
CI104_RS24890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CI104_RS24895	COG0456	acetyltransferase
CI104_RS24900	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CI104_RS24905	COG1088	dTDP-glucose 4,6-dehydratase activity
CI104_RS24910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CI104_RS24930	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CI104_RS24940	COG3118	belongs to the thioredoxin family
CI104_RS24975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CI104_RS25010	COG3978	acetolactate synthase activity
CI104_RS25025	COG0606	chelatase, subunit chli
CI104_RS25030	COG3085	chromosome segregation
CI104_RS25070	COG2186	Transcriptional regulator
CI104_RS25075	COG0477	Major facilitator Superfamily
CI104_RS25080	COG1609	Transcriptional regulator
CI104_RS25085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI104_RS25090	COG1879	ABC-type sugar transport system periplasmic component
CI104_RS25095	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI104_RS25105	COG1869	D-ribose catabolic process
CI104_RS25130	COG1522	sequence-specific DNA binding
CI104_RS25135	COG0716	FMN binding
CI104_RS25150	COG3312	ion transport
CI104_RS25175	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CI104_RS25180	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CI104_RS25185	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CI104_RS25190	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CI104_RS25205	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CI104_RS25210	COG0573	inorganic phosphate transmembrane transporter activity
CI104_RS25215	COG0581	inorganic phosphate transmembrane transporter activity
CI104_RS25225	COG0704	Plays a role in the regulation of phosphate uptake
CI104_RS25230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CI104_RS25235	COG2252	PERMEase
CI104_RS25240	COG0431	NADPH-dependent FMN reductase
CI104_RS25245	COG2091	lysine biosynthetic process via aminoadipic acid
CI104_RS25250	COG0814	amino acid
CI104_RS25350	COG1192	Involved in chromosome partitioning
CI104_RS25440	COG0210	DNA helicase
CI104_RS25610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CI104_RS25665	COG1357	PFAM Pentapeptide repeats (8 copies)
CI104_RS25695	COG1357	PFAM Pentapeptide repeats (8 copies)
CI104_RS25725	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CI104_RS25790	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CI104_RS25875	COG2801	Transposase and inactivated derivatives
CI104_RS25880	COG3547	Transposase (IS116 IS110 IS902 family)
CI104_RS25895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CI104_RS25905	COG3077	Addiction module antitoxin, RelB DinJ family
CI104_RS25910	COG2026	Addiction module toxin, RelE StbE family
CI104_RS26070	COG3157	Type VI secretion system effector, Hcp
CI104_RS26085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CI104_RS26105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CI104_RS26105	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CI104_RS26165	COG2801	Transposase and inactivated derivatives
CI104_RS26180	COG2801	Transposase and inactivated derivatives
CI104_RS26185	COG0431	NADPH-dependent FMN reductase
CI104_RS26190	COG0640	Transcriptional regulator
CI104_RS26195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CI104_RS26200	COG1393	Belongs to the ArsC family
CI104_RS26205	COG0589	response to stress
CI104_RS26210	COG0659	secondary active sulfate transmembrane transporter activity
CI104_RS26305	COG2205	protein histidine kinase activity
CI104_RS26315	COG2194	sulfuric ester hydrolase activity
CI104_RS26340	COG1294	oxidase, subunit
CI104_RS26350	COG1454	alcohol dehydrogenase
CI104_RS26370	COG1252	NADH dehydrogenase
CI104_RS26410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CI104_RS26430	COG1196	nuclear chromosome segregation
CI104_RS26585	COG0789	Transcriptional regulator
CI104_RS26640	COG0789	Transcriptional regulator
CI104_RS26665	COG3550	peptidyl-serine autophosphorylation
CI104_RS26740	COG3173	Aminoglycoside phosphotransferase
CI104_RS26760	COG1660	Displays ATPase and GTPase activities
CI104_RS26820	COG1695	Transcriptional regulator
CI104_RS26895	COG1349	DNA-binding transcription factor activity
CI104_RS26905	COG2084	Dehydrogenase
CI104_RS26915	COG0235	Class ii aldolase
CI104_RS27080	COG2890	protein-(glutamine-N5) methyltransferase activity
CI104_RS27145	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CI104_RS27195	COG0659	secondary active sulfate transmembrane transporter activity
CI104_RS27200	COG0589	response to stress
CI104_RS27240	COG1136	(ABC) transporter
CI104_RS27255	COG1309	transcriptional regulator
CI104_RS27275	COG3039	Transposase
CI104_RS27280	COG1309	transcriptional regulator
CI104_RS27285	COG3250	beta-galactosidase activity
CI104_RS27305	COG0246	Mannitol dehydrogenase
CI104_RS27315	COG2186	Transcriptional regulator
CI104_RS27320	COG4372	Transposase
CI104_RS27325	COG4644	lycopene metabolic process
CI104_RS27370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CI104_RS27440	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CI104_RS27500	COG3039	Transposase
CI104_RS27525	COG3039	Transposase
CI104_RS27560	COG4372	Transposase
CI104_RS27565	COG3436	PFAM IS66 Orf2 family protein
CI104_RS27575	COG0840	transmembrane signaling receptor activity
CI104_RS27590	COG1662	PFAM IS1 transposase
CI104_RS27590	COG3677	Transposase
CI104_RS27635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CI104_RS27635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CI104_RS27915	COG2135	peptidase activity
CI104_RS27950	COG1121	(ABC) transporter
CI104_RS27975	COG2963	transposase activity
CI104_RS27985	COG4372	Transposase
CI104_RS27990	COG3436	PFAM IS66 Orf2 family protein
CI104_RS28000	COG2826	transposase and inactivated derivatives, IS30 family
CI104_RS28005	COG2963	transposase activity
CI104_RS28010	COG2801	Transposase and inactivated derivatives
CI104_RS28020	COG0456	acetyltransferase
CI104_RS28185	COG1475	DNA binding
CI104_RS28470	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CI104_RS28545	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CI104_RS28580	COG5433	transposase activity
CI104_RS28605	COG4644	lycopene metabolic process
CI104_RS28645	COG3300	MHYT domain
CI104_RS28645	COG5001	Diguanylate cyclase