locus-tag	class	description
AM348_RS00010	COG2814	Major facilitator Superfamily
AM348_RS00045	COG1414	Transcriptional regulator
AM348_RS00070	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AM348_RS00085	COG1609	Transcriptional regulator
AM348_RS00100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM348_RS00105	COG2079	MmgE PrpD family protein
AM348_RS00110	COG0372	Belongs to the citrate synthase family
AM348_RS00120	COG3829	transcription factor binding
AM348_RS00130	COG1280	lysine exporter protein (LysE YggA)
AM348_RS00135	COG3706	GGDEF domain
AM348_RS00140	COG0348	domain, Protein
AM348_RS00160	COG0583	DNA-binding transcription factor activity
AM348_RS00180	COG3069	C4-dicarboxylate transmembrane transporter activity
AM348_RS00185	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM348_RS00200	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AM348_RS00205	COG0693	protein deglycase activity
AM348_RS00210	COG2957	Belongs to the agmatine deiminase family
AM348_RS00215	COG2200	EAL domain
AM348_RS00220	COG0531	amino acid
AM348_RS00225	COG0174	glutamine synthetase
AM348_RS00230	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM348_RS00235	COG1396	sequence-specific DNA binding
AM348_RS00235	COG1917	Cupin 2, conserved barrel domain protein
AM348_RS00240	COG1012	belongs to the aldehyde dehydrogenase family
AM348_RS00245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM348_RS00260	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AM348_RS00265	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM348_RS00270	COG1999	signal sequence binding
AM348_RS00275	COG1773	rubredoxin
AM348_RS00280	COG1271	oxidase subunit
AM348_RS00285	COG1294	oxidase, subunit
AM348_RS00310	COG1609	Transcriptional regulator
AM348_RS00315	COG1757	Na H antiporter
AM348_RS00320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM348_RS00350	COG0582	viral genome integration into host DNA
AM348_RS00365	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM348_RS00395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM348_RS00405	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AM348_RS00430	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM348_RS00440	COG3034	peptidoglycan biosynthetic process
AM348_RS00445	COG0121	glutamine amidotransferase
AM348_RS00460	COG1960	acyl-CoA dehydrogenase activity
AM348_RS00465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM348_RS00475	COG2200	EAL domain
AM348_RS00490	COG3539	Fimbrial protein
AM348_RS00500	COG3121	Chaperone
AM348_RS00505	COG3188	usher protein
AM348_RS00515	COG3539	Fimbrial protein
AM348_RS00520	COG0745	RESPONSE REGULATOR receiver
AM348_RS00535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM348_RS00545	COG2226	methyltransferase
AM348_RS00555	COG0741	lytic transglycosylase activity
AM348_RS00555	COG1388	LysM domain
AM348_RS00560	COG2226	methyltransferase
AM348_RS00570	COG2814	Major facilitator Superfamily
AM348_RS00575	COG0583	DNA-binding transcription factor activity
AM348_RS00615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM348_RS00625	COG2011	ABC-type metal ion transport system permease component
AM348_RS00630	COG1464	Belongs to the NlpA lipoprotein family
AM348_RS00640	COG1720	tRNA m6t6A37 methyltransferase activity
AM348_RS00650	COG3015	lipoprotein NlpE involved in copper resistance
AM348_RS00655	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM348_RS00670	COG4568	rho-dependent transcription termination
AM348_RS00680	COG0346	lactoylglutathione lyase activity
AM348_RS00685	COG1982	Orn Lys Arg decarboxylase major
AM348_RS00720	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM348_RS00725	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AM348_RS00740	COG0575	Belongs to the CDS family
AM348_RS00750	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM348_RS00800	COG3835	regulator
AM348_RS00830	COG2860	membrane
AM348_RS00855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM348_RS00860	COG1120	ATPase activity
AM348_RS00865	COG4774	siderophore transport
AM348_RS00875	COG3188	usher protein
AM348_RS00880	COG3121	Chaperone
AM348_RS00890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM348_RS00895	COG1643	Atp-dependent helicase
AM348_RS00900	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM348_RS00920	COG0617	tRNA 3'-terminal CCA addition
AM348_RS00925	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM348_RS00935	COG3121	Chaperone
AM348_RS00940	COG3188	usher protein
AM348_RS00945	COG3539	Fimbrial protein
AM348_RS00950	COG3539	Fimbrial protein
AM348_RS00965	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AM348_RS00980	COG0726	polysaccharide deacetylase
AM348_RS00985	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM348_RS00990	COG0842	Transport permease protein
AM348_RS00995	COG1131	(ABC) transporter
AM348_RS01000	COG0288	reversible hydration of carbon dioxide
AM348_RS01005	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AM348_RS01010	COG4993	Dehydrogenase
AM348_RS01070	COG3064	Membrane
AM348_RS01080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM348_RS01085	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM348_RS01090	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM348_RS01105	COG2211	Major facilitator Superfamily
AM348_RS01110	COG3940	Belongs to the glycosyl hydrolase 43 family
AM348_RS01115	COG3725	Membrane protein required for beta-lactamase induction
AM348_RS01130	COG4969	Belongs to the N-Me-Phe pilin family
AM348_RS01135	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM348_RS01140	COG1459	type II secretion system
AM348_RS01150	COG0237	dephospho-CoA kinase activity
AM348_RS01165	COG0494	nUDIX hydrolase
AM348_RS01185	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM348_RS01190	COG0849	cell division
AM348_RS01200	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM348_RS01215	COG0772	Belongs to the SEDS family
AM348_RS01220	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AM348_RS01230	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM348_RS01235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM348_RS01240	COG0768	penicillin binding
AM348_RS01275	COG0028	Belongs to the TPP enzyme family
AM348_RS01310	COG1609	Transcriptional regulator
AM348_RS01320	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS01325	COG2814	Major facilitator Superfamily
AM348_RS01345	COG1178	ABC-type Fe3 transport system permease component
AM348_RS01355	COG0586	Pfam SNARE associated Golgi protein
AM348_RS01375	COG0235	Class ii aldolase
AM348_RS01385	COG0417	DNA replication proofreading
AM348_RS01395	COG0564	pseudouridine synthase activity
AM348_RS01415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM348_RS01465	COG2271	Major facilitator Superfamily
AM348_RS01475	COG0644	oxidoreductase
AM348_RS01530	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AM348_RS01535	COG0505	Belongs to the CarA family
AM348_RS01545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM348_RS01565	COG1047	Peptidyl-prolyl cis-trans
AM348_RS01580	COG0196	riboflavin kinase activity
AM348_RS01605	COG0583	DNA-binding transcription factor activity
AM348_RS01620	COG0443	Heat shock 70 kDa protein
AM348_RS01635	COG1584	GPR1 FUN34 yaaH family protein
AM348_RS01645	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM348_RS01655	COG1115	amino acid carrier protein
AM348_RS01665	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM348_RS01675	COG0460	homoserine dehydrogenase
AM348_RS01675	COG0527	aspartate kinase activity
AM348_RS01685	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM348_RS01695	COG0745	RESPONSE REGULATOR receiver
AM348_RS01700	COG4452	Inner membrane protein CreD
AM348_RS01705	COG2205	protein histidine kinase activity
AM348_RS01710	COG0745	RESPONSE REGULATOR receiver
AM348_RS01715	COG3045	CreA protein
AM348_RS01720	COG2207	Transcriptional regulator
AM348_RS01720	COG3708	Transcriptional regulator
AM348_RS01740	COG0741	lytic transglycosylase activity
AM348_RS01745	COG0488	(ABC) transporter
AM348_RS01760	COG0560	Phosphoserine phosphatase
AM348_RS01770	COG3726	membrane protein affecting hemolysin expression
AM348_RS01800	COG1328	CTP reductase activity
AM348_RS01805	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM348_RS01810	COG0084	hydrolase, TatD family'
AM348_RS01815	COG4667	esterase of the alpha-beta hydrolase superfamily
AM348_RS01820	COG5487	UPF0391 membrane protein
AM348_RS01825	COG2823	Periplasmic or secreted lipoprotein
AM348_RS01835	COG1011	Hydrolase
AM348_RS01840	COG0456	acetyltransferase
AM348_RS01845	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AM348_RS01875	COG3706	GGDEF domain
AM348_RS01880	COG4114	ferric iron reductase
AM348_RS01885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM348_RS01890	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM348_RS01895	COG2197	response regulator
AM348_RS01900	COG2197	response regulator
AM348_RS01905	COG2966	Psort location CytoplasmicMembrane, score
AM348_RS01920	COG1484	DNA-dependent DNA replication
AM348_RS01940	COG1063	alcohol dehydrogenase
AM348_RS01945	COG1802	Transcriptional regulator
AM348_RS01950	COG2271	Major facilitator Superfamily
AM348_RS01960	COG0840	transmembrane signaling receptor activity
AM348_RS01965	COG1966	Carbon starvation protein
AM348_RS01970	COG2879	small protein
AM348_RS01975	COG0523	cobalamin synthesis protein
AM348_RS01985	COG1566	PFAM secretion protein HlyD family protein
AM348_RS01995	COG5457	Domain of unknown function (DUF1127)
AM348_RS02000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM348_RS02025	COG0626	cystathionine gamma-synthase activity
AM348_RS02030	COG1301	dicarboxylic acid transport
AM348_RS02035	COG0583	DNA-binding transcription factor activity
AM348_RS02040	COG2733	membrane
AM348_RS02050	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AM348_RS02055	COG1924	4 iron, 4 sulfur cluster binding
AM348_RS02065	COG0477	Major facilitator Superfamily
AM348_RS02075	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM348_RS02085	COG2186	Transcriptional regulator
AM348_RS02090	COG0246	Mannitol dehydrogenase
AM348_RS02100	COG2610	gluconate transmembrane transporter activity
AM348_RS02105	COG1556	Lactate utilization protein
AM348_RS02110	COG1139	Iron-sulfur cluster binding protein
AM348_RS02115	COG0247	lactate metabolic process
AM348_RS02120	COG1620	l-lactate permease
AM348_RS02145	COG0531	amino acid
AM348_RS02150	COG1012	belongs to the aldehyde dehydrogenase family
AM348_RS02155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM348_RS02240	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM348_RS02260	COG1476	TRANSCRIPTIONal
AM348_RS02265	COG3423	Transcriptional regulator
AM348_RS02280	COG3732	PTS system glucitol sorbitol-specific
AM348_RS02285	COG0673	inositol 2-dehydrogenase activity
AM348_RS02345	COG0582	viral genome integration into host DNA
AM348_RS02355	COG1064	alcohol dehydrogenase
AM348_RS02360	COG0433	COG0433 Predicted ATPase
AM348_RS02365	COG0795	lipopolysaccharide-transporting ATPase activity
AM348_RS02370	COG0795	lipopolysaccharide-transporting ATPase activity
AM348_RS02385	COG2927	DNA polymerase III (CHI subunit)
AM348_RS02390	COG0525	valine-tRNA ligase activity
AM348_RS02420	COG2731	YhcH YjgK YiaL family protein
AM348_RS02475	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AM348_RS02495	COG1263	PTS System
AM348_RS02495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM348_RS02500	COG0366	Alpha amylase catalytic
AM348_RS02515	COG3711	transcriptional antiterminator
AM348_RS02515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM348_RS02530	COG3964	amidohydrolase
AM348_RS02565	COG0312	modulator of DNA gyrase
AM348_RS02575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM348_RS02590	COG0840	transmembrane signaling receptor activity
AM348_RS02595	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM348_RS02600	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM348_RS02605	COG1129	ABC transporter
AM348_RS02610	COG1879	ABC-type sugar transport system periplasmic component
AM348_RS02635	COG3157	Type VI secretion system effector, Hcp
AM348_RS02640	COG3391	amine dehydrogenase activity
AM348_RS02645	COG4771	TonB-dependent receptor
AM348_RS02650	COG2105	PFAM AIG2 family protein
AM348_RS02655	COG2911	Protein conserved in bacteria
AM348_RS02660	COG0729	surface antigen
AM348_RS02670	COG1253	flavin adenine dinucleotide binding
AM348_RS02685	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM348_RS02690	COG1218	3'(2'),5'-bisphosphate nucleotidase
AM348_RS02700	COG1733	regulation of RNA biosynthetic process
AM348_RS02705	COG0702	epimerase
AM348_RS02715	COG0697	spore germination
AM348_RS02720	COG0840	transmembrane signaling receptor activity
AM348_RS02730	COG1113	amino acid transport
AM348_RS02735	COG0545	Peptidyl-prolyl cis-trans isomerase
AM348_RS02740	COG3061	Opacity-associated protein A
AM348_RS02755	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM348_RS02770	COG0730	response to heat
AM348_RS02820	COG1073	alpha beta
AM348_RS02825	COG3650	response to hydrogen peroxide
AM348_RS02835	COG1960	acyl-CoA dehydrogenase activity
AM348_RS02840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM348_RS02845	COG0557	exoribonuclease II activity
AM348_RS02865	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AM348_RS02870	COG0330	HflC and HflK could
AM348_RS02875	COG0330	HflC and HflK could
AM348_RS02880	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM348_RS02885	COG1923	regulation of RNA biosynthetic process
AM348_RS02900	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM348_RS02905	COG0802	atpase or kinase
AM348_RS02910	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM348_RS02910	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM348_RS02915	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM348_RS02950	COG1511	domain protein
AM348_RS02950	COG3264	Mechanosensitive ion channel
AM348_RS02965	COG1053	succinate dehydrogenase
AM348_RS02970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM348_RS03025	COG1509	lysine 2,3-aminomutase activity
AM348_RS03050	COG0531	amino acid
AM348_RS03055	COG3030	protein affecting phage T7 exclusion by the F plasmid
AM348_RS03060	COG1027	Aspartate ammonia-lyase
AM348_RS03065	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM348_RS03080	COG1309	transcriptional regulator
AM348_RS03095	COG0318	PFAM AMP-dependent synthetase and ligase
AM348_RS03130	COG3290	protein histidine kinase activity
AM348_RS03135	COG4565	transcriptional regulatory protein
AM348_RS03140	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM348_RS03145	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM348_RS03145	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM348_RS03150	COG3647	Membrane
AM348_RS03160	COG2211	Major facilitator Superfamily
AM348_RS03165	COG1486	melibiose metabolic process
AM348_RS03170	COG2169	Transcriptional regulator
AM348_RS03175	COG1982	Orn Lys Arg decarboxylase major
AM348_RS03180	COG2207	Transcriptional regulator
AM348_RS03185	COG0531	amino acid
AM348_RS03225	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AM348_RS03235	COG2824	Alkylphosphonate utilization operon protein PhnA
AM348_RS03240	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AM348_RS03245	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AM348_RS03250	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM348_RS03255	COG3639	organic phosphonate transmembrane transporter activity
AM348_RS03260	COG2188	Transcriptional regulator
AM348_RS03265	COG3624	Phosphonate C-P lyase system protein PhnG
AM348_RS03270	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AM348_RS03275	COG3626	phosphonate metabolism
AM348_RS03280	COG3627	carbon phosphorus lyase activity
AM348_RS03285	COG4107	phosphonate C-P lyase system protein PhnK
AM348_RS03290	COG4778	phosphonate C-P lyase system protein PhnL
AM348_RS03295	COG3454	Phosphonate metabolism
AM348_RS03300	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AM348_RS03305	COG0456	acetyltransferase
AM348_RS03310	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM348_RS03315	COG3093	addiction module antidote protein HigA
AM348_RS03330	COG4191	Histidine kinase
AM348_RS03330	COG0784	Response regulator, receiver
AM348_RS03340	COG1129	ABC transporter
AM348_RS03345	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM348_RS03380	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM348_RS03385	COG1301	dicarboxylic acid transport
AM348_RS03390	COG4235	cytochrome complex assembly
AM348_RS03395	COG1138	Cytochrome C-type biogenesis protein
AM348_RS03400	COG3301	Polysulphide reductase, NrfD
AM348_RS03405	COG0437	4 iron, 4 sulfur cluster binding
AM348_RS03410	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AM348_RS03425	COG3162	membrane
AM348_RS03435	COG1346	cytolysis
AM348_RS03440	COG1380	Effector of murein hydrolase LrgA
AM348_RS03445	COG0583	DNA-binding transcription factor activity
AM348_RS03450	COG0025	NhaP-type Na H and K H
AM348_RS03455	COG2252	PERMEase
AM348_RS03465	COG0789	Transcriptional regulator
AM348_RS03475	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM348_RS03485	COG0629	single-stranded DNA binding
AM348_RS03495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM348_RS03510	COG3547	Transposase (IS116 IS110 IS902 family)
AM348_RS03520	COG2315	Protein conserved in bacteria
AM348_RS03525	COG3700	Belongs to the class B bacterial acid phosphatase family
AM348_RS03530	COG1448	Aminotransferase
AM348_RS03540	COG0305	Participates in initiation and elongation during chromosome replication
AM348_RS03555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM348_RS03565	COG0735	belongs to the Fur family
AM348_RS03570	COG3237	CsbD-like
AM348_RS03575	COG0534	Mate efflux family protein
AM348_RS03585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM348_RS03620	COG2182	Extracellular solute-binding protein
AM348_RS03630	COG3833	ABC-type maltose transport systems, permease component
AM348_RS03635	COG2814	Major facilitator Superfamily
AM348_RS03635	COG0477	Major facilitator Superfamily
AM348_RS03640	COG3223	Belongs to the PsiE family
AM348_RS03645	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM348_RS03675	COG0527	aspartate kinase activity
AM348_RS03695	COG0561	phosphatase activity
AM348_RS03710	COG1187	pseudouridine synthase activity
AM348_RS03750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM348_RS03780	COG3657	addiction module killer protein
AM348_RS03785	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM348_RS03800	COG1410	methionine synthase
AM348_RS03800	COG0646	methionine synthase
AM348_RS03810	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AM348_RS03820	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM348_RS03830	COG0456	acetyltransferase
AM348_RS03870	COG0151	Belongs to the GarS family
AM348_RS03880	COG4191	Histidine kinase
AM348_RS03935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM348_RS03940	COG2104	thiamine diphosphate biosynthetic process
AM348_RS03955	COG1278	Cold shock
AM348_RS03965	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM348_RS04005	COG0250	Participates in transcription elongation, termination and antitermination
AM348_RS04050	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM348_RS04110	COG0583	DNA-binding transcription factor activity
AM348_RS04145	COG2194	sulfuric ester hydrolase activity
AM348_RS04150	COG2207	Transcriptional regulator
AM348_RS04155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM348_RS04160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM348_RS04165	COG1882	Formate acetyltransferase
AM348_RS04170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM348_RS04175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM348_RS04180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM348_RS04180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM348_RS04180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM348_RS04190	COG0371	Dehydrogenase
AM348_RS04200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM348_RS04210	COG0583	DNA-binding transcription factor activity
AM348_RS04220	COG0737	Belongs to the 5'-nucleotidase family
AM348_RS04230	COG0460	homoserine dehydrogenase
AM348_RS04230	COG0527	aspartate kinase activity
AM348_RS04235	COG0626	cystathionine gamma-synthase activity
AM348_RS04245	COG2211	Major facilitator Superfamily
AM348_RS04265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM348_RS04270	COG1609	Transcriptional regulator
AM348_RS04280	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM348_RS04295	COG1575	Belongs to the MenA family. Type 1 subfamily
AM348_RS04305	COG3074	FtsZ-dependent cytokinesis
AM348_RS04310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AM348_RS04320	COG1494	fructose-1,6-bisphosphatase
AM348_RS04330	COG3152	Membrane
AM348_RS04345	COG0471	metal ion transport
AM348_RS04360	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM348_RS04375	COG3678	ATP-independent chaperone mediated protein folding
AM348_RS04380	COG0745	RESPONSE REGULATOR receiver
AM348_RS04385	COG2205	protein histidine kinase activity
AM348_RS04390	COG2271	Major facilitator Superfamily
AM348_RS04395	COG1082	Xylose isomerase domain protein TIM barrel
AM348_RS04400	COG2188	Transcriptional regulator
AM348_RS04405	COG2258	MOSC domain
AM348_RS04410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM348_RS04455	COG1454	alcohol dehydrogenase
AM348_RS04470	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM348_RS04505	COG3383	formate dehydrogenase (NAD+) activity
AM348_RS04505	COG0243	molybdopterin cofactor binding
AM348_RS04510	COG0243	molybdopterin cofactor binding
AM348_RS04510	COG3383	formate dehydrogenase (NAD+) activity
AM348_RS04515	COG0437	4 iron, 4 sulfur cluster binding
AM348_RS04520	COG2864	formate dehydrogenase
AM348_RS04535	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AM348_RS04545	COG4680	protein conserved in bacteria
AM348_RS04550	COG5499	transcription regulator containing HTH domain
AM348_RS04555	COG0456	acetyltransferase
AM348_RS04560	COG1490	D-aminoacyl-tRNA deacylase activity
AM348_RS04570	COG1011	Hydrolase
AM348_RS04580	COG0477	Major facilitator Superfamily
AM348_RS04585	COG2814	Major facilitator Superfamily
AM348_RS04590	COG1063	alcohol dehydrogenase
AM348_RS04595	COG3684	Belongs to the aldolase LacD family
AM348_RS04600	COG2084	Dehydrogenase
AM348_RS04605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM348_RS04610	COG1349	DNA-binding transcription factor activity
AM348_RS04630	COG3852	Histidine kinase
AM348_RS04645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM348_RS04665	COG0204	Acyl-transferase
AM348_RS04680	COG3084	Protein conserved in bacteria
AM348_RS04685	COG0746	molybdenum cofactor guanylyltransferase activity
AM348_RS04690	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM348_RS04735	COG1739	Uncharacterized protein family UPF0029
AM348_RS04755	COG1609	Transcriptional regulator
AM348_RS04760	COG1940	carbohydrate kinase activity
AM348_RS04770	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM348_RS04785	COG0805	protein transport
AM348_RS04830	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM348_RS04835	COG0583	DNA-binding transcription factor activity
AM348_RS04840	COG0697	spore germination
AM348_RS04845	COG0561	phosphatase activity
AM348_RS04850	COG2267	carboxylic ester hydrolase activity
AM348_RS04855	COG1280	lysine exporter protein (LysE YggA)
AM348_RS04865	COG1280	lysine exporter protein (LysE YggA)
AM348_RS04885	COG2962	Rard protein
AM348_RS04900	COG1011	Hydrolase
AM348_RS04945	COG2959	enzyme of heme biosynthesis
AM348_RS04950	COG3071	HemY protein
AM348_RS04995	COG2244	polysaccharide biosynthetic process
AM348_RS05000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM348_RS05005	COG0456	acetyltransferase
AM348_RS05010	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM348_RS05015	COG1088	dTDP-glucose 4,6-dehydratase activity
AM348_RS05020	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM348_RS05035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM348_RS05040	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM348_RS05050	COG3118	belongs to the thioredoxin family
AM348_RS05075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM348_RS05095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM348_RS05105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM348_RS05110	COG3978	acetolactate synthase activity
AM348_RS05130	COG3085	chromosome segregation
AM348_RS05170	COG2186	Transcriptional regulator
AM348_RS05175	COG0477	Major facilitator Superfamily
AM348_RS05180	COG1609	Transcriptional regulator
AM348_RS05185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM348_RS05190	COG1879	ABC-type sugar transport system periplasmic component
AM348_RS05195	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM348_RS05205	COG1869	D-ribose catabolic process
AM348_RS05230	COG1522	sequence-specific DNA binding
AM348_RS05235	COG0716	FMN binding
AM348_RS05250	COG3312	ion transport
AM348_RS05275	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AM348_RS05285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AM348_RS05290	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AM348_RS05305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM348_RS05310	COG0573	inorganic phosphate transmembrane transporter activity
AM348_RS05315	COG0581	inorganic phosphate transmembrane transporter activity
AM348_RS05325	COG0704	Plays a role in the regulation of phosphate uptake
AM348_RS05330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM348_RS05335	COG2252	PERMEase
AM348_RS05340	COG0431	NADPH-dependent FMN reductase
AM348_RS05345	COG2091	lysine biosynthetic process via aminoadipic acid
AM348_RS05380	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AM348_RS05395	COG0592	DNA-directed DNA polymerase activity
AM348_RS05410	COG0561	phosphatase activity
AM348_RS05435	COG0823	Involved in the tonB-independent uptake of proteins
AM348_RS05440	COG5645	(Lipo)protein
AM348_RS05460	COG2149	membrane
AM348_RS05470	COG0641	radical SAM
AM348_RS05480	COG2610	gluconate transmembrane transporter activity
AM348_RS05485	COG0583	DNA-binding transcription factor activity
AM348_RS05495	COG2814	Major facilitator Superfamily
AM348_RS05515	COG0028	Belongs to the TPP enzyme family
AM348_RS05520	COG0440	acetolactate synthase activity
AM348_RS05525	COG1349	DNA-binding transcription factor activity
AM348_RS05535	COG0738	Major facilitator superfamily
AM348_RS05545	COG2197	response regulator
AM348_RS05585	COG4580	involved in the transport of maltose and maltodextrins
AM348_RS05590	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM348_RS05595	COG2723	6-phospho-beta-galactosidase activity
AM348_RS05600	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM348_RS05600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM348_RS05605	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM348_RS05610	COG1609	Transcriptional regulator
AM348_RS05625	COG5464	transposase or invertase
AM348_RS05630	COG1464	Belongs to the NlpA lipoprotein family
AM348_RS05635	COG0697	spore germination
AM348_RS05645	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS05655	COG0604	alcohol dehydrogenase
AM348_RS05660	COG0583	DNA-binding transcription factor activity
AM348_RS05680	COG2771	luxR family
AM348_RS05725	COG2211	Major facilitator Superfamily
AM348_RS05730	COG1501	Belongs to the glycosyl hydrolase 31 family
AM348_RS05735	COG3711	transcriptional antiterminator
AM348_RS05740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM348_RS05740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM348_RS05740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM348_RS05745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM348_RS05750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM348_RS05750	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM348_RS05760	COG0191	fructose-bisphosphate aldolase activity
AM348_RS05770	COG2982	Protein involved in outer membrane biogenesis
AM348_RS05775	COG2233	PERMEase
AM348_RS05780	COG0786	glutamate:sodium symporter activity
AM348_RS05785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM348_RS05790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM348_RS05795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM348_RS05815	COG2860	membrane
AM348_RS05820	COG1561	YicC-like family, N-terminal region
AM348_RS05855	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM348_RS05870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AM348_RS05885	COG1519	Transferase
AM348_RS05890	COG0859	PFAM glycosyl transferase family 9
AM348_RS05895	COG0438	transferase activity, transferring glycosyl groups
AM348_RS05900	COG0515	serine threonine protein kinase
AM348_RS05915	COG0859	PFAM glycosyl transferase family 9
AM348_RS05925	COG0859	PFAM glycosyl transferase family 9
AM348_RS05935	COG0156	8-amino-7-oxononanoate synthase activity
AM348_RS05950	COG1216	Glycosyl transferase, family 2
AM348_RS05955	COG2861	carbohydrate metabolic process
AM348_RS05960	COG4942	peptidase
AM348_RS05970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM348_RS05975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM348_RS05990	COG1045	serine acetyltransferase
AM348_RS06000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM348_RS06005	COG1304	FMN binding
AM348_RS06010	COG2186	Transcriptional regulator
AM348_RS06045	COG3722	fumarate hydratase activity
AM348_RS06055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM348_RS06055	COG2213	PTS system mannitol-specific
AM348_RS06065	COG1566	PFAM secretion protein HlyD family protein
AM348_RS06070	COG0625	glutathione transferase activity
AM348_RS06080	COG3276	selenocysteine insertion sequence binding
AM348_RS06085	COG1454	alcohol dehydrogenase
AM348_RS06090	COG1012	belongs to the aldehyde dehydrogenase family
AM348_RS06100	COG1566	PFAM secretion protein HlyD family protein
AM348_RS06105	COG0583	DNA-binding transcription factor activity
AM348_RS06110	COG3713	MltA-interacting MipA family protein
AM348_RS06120	COG2211	Major facilitator Superfamily
AM348_RS06125	COG4977	sequence-specific DNA binding
AM348_RS06125	COG1917	Cupin 2, conserved barrel domain protein
AM348_RS06130	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM348_RS06135	COG3977	Valine--pyruvate aminotransferase
AM348_RS06140	COG0366	Alpha amylase catalytic
AM348_RS06150	COG2992	FlgJ-related protein
AM348_RS06155	COG2207	Transcriptional regulator
AM348_RS06155	COG1609	Transcriptional regulator
AM348_RS06165	COG1070	Carbohydrate kinase
AM348_RS06170	COG4682	membrane
AM348_RS06175	COG3274	enterobacterial common antigen metabolic process
AM348_RS06200	COG1278	Cold shock
AM348_RS06205	COG2944	sequence-specific DNA binding
AM348_RS06220	COG2814	Major facilitator Superfamily
AM348_RS06225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM348_RS06235	COG1609	Transcriptional regulator
AM348_RS06240	COG2885	chlorophyll binding
AM348_RS06245	COG0243	molybdopterin cofactor binding
AM348_RS06250	COG0456	acetyltransferase
AM348_RS06255	COG2818	Glycosylase
AM348_RS06260	COG5571	outer membrane autotransporter
AM348_RS06265	COG2223	nitrite transmembrane transporter activity
AM348_RS06290	COG0747	negative chemotaxis
AM348_RS06300	COG0601	transmembrane transport
AM348_RS06305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM348_RS06310	COG0444	Belongs to the ABC transporter superfamily
AM348_RS06315	COG4608	Belongs to the ABC transporter superfamily
AM348_RS06320	COG2204	response regulator
AM348_RS06325	COG0814	amino acid
AM348_RS06330	COG0626	cystathionine gamma-synthase activity
AM348_RS06340	COG2200	EAL domain
AM348_RS06340	COG2199	diguanylate cyclase activity
AM348_RS06365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM348_RS06370	COG2200	EAL domain
AM348_RS06375	COG2982	Protein involved in outer membrane biogenesis
AM348_RS06380	COG0477	Major facilitator Superfamily
AM348_RS06385	COG1295	ribonuclease BN
AM348_RS06390	COG0583	DNA-binding transcription factor activity
AM348_RS06395	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS06400	COG2197	response regulator
AM348_RS06410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM348_RS06425	COG1858	cytochrome C peroxidase
AM348_RS06430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM348_RS06435	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM348_RS06440	COG0339	signal peptide processing
AM348_RS06455	COG1959	2 iron, 2 sulfur cluster binding
AM348_RS06465	COG0589	response to stress
AM348_RS06475	COG0306	phosphate transporter
AM348_RS06480	COG2081	HI0933 family
AM348_RS06485	COG2186	Transcriptional regulator
AM348_RS06490	COG0246	Mannitol dehydrogenase
AM348_RS06500	COG1063	alcohol dehydrogenase
AM348_RS06505	COG2271	Major facilitator Superfamily
AM348_RS06525	COG0277	FAD linked oxidase domain protein
AM348_RS06540	COG1454	alcohol dehydrogenase
AM348_RS06545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM348_RS06550	COG1129	ABC transporter
AM348_RS06550	COG0842	Transport permease protein
AM348_RS06555	COG0842	Transport permease protein
AM348_RS06575	COG3479	Phenolic acid decarboxylase
AM348_RS06580	COG2091	lysine biosynthetic process via aminoadipic acid
AM348_RS06585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM348_RS06590	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS06600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM348_RS06625	COG1216	Glycosyl transferase, family 2
AM348_RS06645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM348_RS06675	COG0628	permease
AM348_RS06680	COG0477	Major facilitator Superfamily
AM348_RS06690	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM348_RS06705	COG3714	YhhN family
AM348_RS06715	COG3776	membrane
AM348_RS06720	COG0742	ribosomal rna small subunit methyltransferase
AM348_RS06725	COG0552	protein localization to endoplasmic reticulum
AM348_RS06730	COG2884	Cell division ATP-binding protein ftsE
AM348_RS06735	COG2177	Part of the ABC transporter FtsEX involved in
AM348_RS06760	COG0683	leucine binding
AM348_RS06770	COG4177	L-phenylalanine transmembrane transporter activity
AM348_RS06775	COG0411	ABC transporter
AM348_RS06810	COG0584	glycerophosphoryl diester phosphodiesterase
AM348_RS06820	COG0405	Gamma-glutamyltransferase
AM348_RS06830	COG3157	Type VI secretion system effector, Hcp
AM348_RS06840	COG1247	-acetyltransferase
AM348_RS06845	COG0673	inositol 2-dehydrogenase activity
AM348_RS06850	COG1741	Belongs to the pirin family
AM348_RS06855	COG1609	Transcriptional regulator
AM348_RS06860	COG3265	gluconokinase activity
AM348_RS06865	COG2610	gluconate transmembrane transporter activity
AM348_RS06885	COG2095	MarC family integral membrane protein
AM348_RS06890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM348_RS06915	COG0058	SHG alpha-glucan phosphorylase activity
AM348_RS06920	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM348_RS06935	COG1349	DNA-binding transcription factor activity
AM348_RS06945	COG0058	SHG alpha-glucan phosphorylase activity
AM348_RS06950	COG1640	4-alpha-glucanotransferase
AM348_RS06955	COG2610	gluconate transmembrane transporter activity
AM348_RS06965	COG1040	competence protein
AM348_RS06990	COG1918	ferrous iron import across plasma membrane
AM348_RS06995	COG2183	response to ionizing radiation
AM348_RS07000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM348_RS07020	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM348_RS07030	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM348_RS07035	COG1011	Hydrolase
AM348_RS07045	COG0494	nUDIX hydrolase
AM348_RS07050	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM348_RS07055	COG4972	Pilus assembly protein
AM348_RS07075	COG4796	Type ii and iii secretion system protein
AM348_RS07090	COG3266	domain, Protein
AM348_RS07095	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AM348_RS07100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM348_RS07110	COG0180	Tryptophanyl-tRNA synthetase
AM348_RS07140	COG2146	nitrite reductase [NAD(P)H] activity
AM348_RS07145	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM348_RS07170	COG0512	Glutamine amidotransferase of anthranilate synthase
AM348_RS07175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM348_RS07180	COG1289	transmembrane transporter activity
AM348_RS07200	COG1765	OsmC-like protein
AM348_RS07205	COG3954	Phosphoribulokinase
AM348_RS07215	COG0429	hydrolase of the alpha beta-hydrolase fold
AM348_RS07225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM348_RS07235	COG0488	(ABC) transporter
AM348_RS07255	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM348_RS07260	COG1047	Peptidyl-prolyl cis-trans
AM348_RS07270	COG0545	Peptidyl-prolyl cis-trans isomerase
AM348_RS07275	COG2964	Protein conserved in bacteria
AM348_RS07300	COG0049	tRNA binding
AM348_RS07335	COG0051	transcription antitermination factor activity, RNA binding
AM348_RS07345	COG0088	Forms part of the polypeptide exit tunnel
AM348_RS07360	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM348_RS07435	COG0200	Binds to the 23S rRNA
AM348_RS07440	COG0201	protein transport
AM348_RS07455	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AM348_RS07480	COG0789	Transcriptional regulator
AM348_RS07485	COG3036	rescue of stalled ribosome
AM348_RS07495	COG0569	domain protein
AM348_RS07515	COG0758	DNA mediated transformation
AM348_RS07525	COG0551	DNA topoisomerase type I activity
AM348_RS07545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM348_RS07595	COG1126	abc transporter atp-binding protein
AM348_RS07600	COG0765	amino acid transport
AM348_RS07605	COG4597	amino acid ABC transporter
AM348_RS07610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM348_RS07620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM348_RS07625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM348_RS07630	COG1309	transcriptional regulator
AM348_RS07640	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AM348_RS07665	COG4145	pantothenate transmembrane transporter activity
AM348_RS07670	COG3924	membrane
AM348_RS07675	COG0439	Biotin carboxylase
AM348_RS07680	COG0511	ligase activity, forming carbon-carbon bonds
AM348_RS07700	COG0604	alcohol dehydrogenase
AM348_RS07705	COG2200	EAL domain
AM348_RS07705	COG2199	diguanylate cyclase activity
AM348_RS07715	COG1077	Cell shape determining protein MreB Mrl
AM348_RS07720	COG1792	Involved in formation and maintenance of cell shape
AM348_RS07725	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM348_RS07740	COG3164	Protein of unknown function
AM348_RS07745	COG0312	modulator of DNA gyrase
AM348_RS07750	COG0583	DNA-binding transcription factor activity
AM348_RS07770	COG2732	(Barnase) inhibitor
AM348_RS07795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM348_RS07800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM348_RS07805	COG3105	Protein conserved in bacteria
AM348_RS07810	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM348_RS07830	COG0625	glutathione transferase activity
AM348_RS07835	COG2969	positive regulation of protein catabolic process
AM348_RS07840	COG3069	C4-dicarboxylate transmembrane transporter activity
AM348_RS07865	COG2731	YhcH YjgK YiaL family protein
AM348_RS07870	COG0402	S-adenosylhomocysteine deaminase activity
AM348_RS07875	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM348_RS07880	COG0493	'glutamate synthase
AM348_RS07885	COG0069	glutamate synthase activity
AM348_RS07885	COG0067	glutamate synthase
AM348_RS07885	COG0070	glutamate synthase
AM348_RS07895	COG1242	4 iron, 4 sulfur cluster binding
AM348_RS07900	COG0784	Response regulator, receiver
AM348_RS07900	COG5002	protein histidine kinase activity
AM348_RS07900	COG2198	Histidine kinase
AM348_RS07905	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM348_RS07915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM348_RS07930	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM348_RS07940	COG1137	ATPase activity
AM348_RS07945	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM348_RS07950	COG3117	lipopolysaccharide transmembrane transporter activity
AM348_RS07955	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM348_RS07965	COG0530	calcium, potassium:sodium antiporter activity
AM348_RS07970	COG1127	ABC transporter
AM348_RS07975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM348_RS07980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM348_RS07985	COG2854	intermembrane phospholipid transfer
AM348_RS07990	COG3113	response to antibiotic
AM348_RS07995	COG5007	Belongs to the BolA IbaG family
AM348_RS08005	COG3423	Transcriptional regulator
AM348_RS08010	COG0142	geranyltranstransferase activity
AM348_RS08015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AM348_RS08020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AM348_RS08025	COG0697	spore germination
AM348_RS08035	COG2027	D-alanyl-D-alanine carboxypeptidase
AM348_RS08055	COG1534	Rna-binding protein
AM348_RS08065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM348_RS08070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM348_RS08080	COG3069	C4-dicarboxylate transmembrane transporter activity
AM348_RS08085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM348_RS08090	COG0583	DNA-binding transcription factor activity
AM348_RS08095	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM348_RS08120	COG0195	Participates in both transcription termination and antitermination
AM348_RS08130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AM348_RS08155	COG0513	Belongs to the DEAD box helicase family
AM348_RS08160	COG0814	amino acid
AM348_RS08165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM348_RS08170	COG0826	peptidase U32
AM348_RS08175	COG0826	peptidase U32
AM348_RS08180	COG3154	lipid carrier protein
AM348_RS08185	COG3153	acetyltransferase
AM348_RS08200	COG0702	epimerase
AM348_RS08205	COG2823	Periplasmic or secreted lipoprotein
AM348_RS08225	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM348_RS08240	COG1063	alcohol dehydrogenase
AM348_RS08245	COG3775	system Galactitol-specific IIC component
AM348_RS08250	COG3414	Phosphotransferase system galactitol-specific IIB component
AM348_RS08255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM348_RS08270	COG2721	sulfolactate sulfo-lyase activity
AM348_RS08280	COG2271	Major facilitator Superfamily
AM348_RS08290	COG2084	Dehydrogenase
AM348_RS08295	COG1929	Belongs to the glycerate kinase type-1 family
AM348_RS08305	COG0583	DNA-binding transcription factor activity
AM348_RS08325	COG1882	Formate acetyltransferase
AM348_RS08330	COG0251	oxidation-reduction process
AM348_RS08335	COG1760	l-serine dehydratase
AM348_RS08345	COG0814	amino acid
AM348_RS08360	COG1741	Belongs to the pirin family
AM348_RS08365	COG0583	DNA-binding transcription factor activity
AM348_RS08370	COG3152	Membrane
AM348_RS08375	COG0435	Glutathione S-transferase
AM348_RS08380	COG2259	Doxx family
AM348_RS08390	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM348_RS08395	COG4575	ribosome binding
AM348_RS08400	COG1422	Protein of unknown function (DUF1090)
AM348_RS08410	COG0586	Pfam SNARE associated Golgi protein
AM348_RS08415	COG2186	Transcriptional regulator
AM348_RS08420	COG2271	Major facilitator Superfamily
AM348_RS08430	COG2721	sulfolactate sulfo-lyase activity
AM348_RS08450	COG0673	inositol 2-dehydrogenase activity
AM348_RS08455	COG1451	nucleotide metabolic process
AM348_RS08465	COG1902	pentaerythritol trinitrate reductase activity
AM348_RS08465	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM348_RS08470	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AM348_RS08470	COG3408	Glycogen debranching enzyme
AM348_RS08480	COG0531	amino acid
AM348_RS08485	COG2731	YhcH YjgK YiaL family protein
AM348_RS08490	COG3250	beta-galactosidase activity
AM348_RS08495	COG1609	Transcriptional regulator
AM348_RS08500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM348_RS08510	COG0840	transmembrane signaling receptor activity
AM348_RS08515	COG1695	Transcriptional regulator
AM348_RS08520	COG2375	cellular response to nickel ion
AM348_RS08530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM348_RS08615	COG0358	DNA primase activity
AM348_RS08620	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM348_RS08635	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM348_RS08645	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AM348_RS08675	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM348_RS08680	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM348_RS08695	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM348_RS08715	COG4991	sh3 domain protein
AM348_RS08725	COG3025	triphosphatase activity
AM348_RS08780	COG3384	dioxygenase
AM348_RS08785	COG0754	glutathionylspermidine amidase activity
AM348_RS08805	COG0494	nUDIX hydrolase
AM348_RS08810	COG3151	Protein conserved in bacteria
AM348_RS08815	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM348_RS08820	COG3150	esterase
AM348_RS08825	COG0187	DNA topoisomerase II activity
AM348_RS08830	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM348_RS08835	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM348_RS08850	COG3111	PFAM Bacterial OB fold (BOF) protein
AM348_RS08865	COG3157	Type VI secretion system effector, Hcp
AM348_RS08885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM348_RS08900	COG0471	metal ion transport
AM348_RS08905	COG0656	L-ascorbic acid biosynthetic process
AM348_RS08910	COG1979	alcohol dehydrogenase
AM348_RS08915	COG2207	Transcriptional regulator
AM348_RS08920	COG0586	Pfam SNARE associated Golgi protein
AM348_RS08925	COG0626	cystathionine gamma-synthase activity
AM348_RS08940	COG0848	biopolymer transport protein
AM348_RS08960	COG0667	Aldo Keto reductase
AM348_RS08970	COG0840	transmembrane signaling receptor activity
AM348_RS08980	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AM348_RS08985	COG0437	4 iron, 4 sulfur cluster binding
AM348_RS08990	COG5557	Pfam Polysulphide reductase, NrfD
AM348_RS08995	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AM348_RS09000	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM348_RS09005	COG1773	rubredoxin
AM348_RS09015	COG0298	carbon dioxide binding
AM348_RS09020	COG0625	glutathione transferase activity
AM348_RS09025	COG0243	molybdopterin cofactor binding
AM348_RS09030	COG0754	glutathionylspermidine amidase activity
AM348_RS09160	COG1811	Na channel or pump
AM348_RS09170	COG1982	Orn Lys Arg decarboxylase major
AM348_RS09175	COG2211	Major facilitator Superfamily
AM348_RS09190	COG1194	a g-specific adenine glycosylase
AM348_RS09200	COG3171	Protein conserved in bacteria
AM348_RS09210	COG0252	asparaginase activity
AM348_RS09215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM348_RS09230	COG0762	integral membrane protein
AM348_RS09235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM348_RS09240	COG2805	Type II/IV secretion system protein
AM348_RS09255	COG0189	ligase activity
AM348_RS09260	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM348_RS09265	COG2356	endonuclease I
AM348_RS09275	COG2814	Major facilitator Superfamily
AM348_RS09300	COG1166	arginine decarboxylase activity
AM348_RS09310	COG0501	Belongs to the peptidase M48B family
AM348_RS09315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM348_RS09335	COG0191	fructose-bisphosphate aldolase activity
AM348_RS09340	COG0668	transmembrane transport
AM348_RS09345	COG1279	arginine transmembrane transporter activity
AM348_RS09350	COG2968	Membrane
AM348_RS09355	COG0583	DNA-binding transcription factor activity
AM348_RS09360	COG0427	acetyl-CoA hydrolase
AM348_RS09365	COG1024	Enoyl-CoA hydratase
AM348_RS09370	COG1703	isobutyryl-CoA mutase activity
AM348_RS09375	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AM348_RS09375	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AM348_RS09390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM348_RS09395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM348_RS09420	COG0006	proline dipeptidase activity
AM348_RS09425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM348_RS09430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM348_RS09455	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS09460	COG2723	6-phospho-beta-galactosidase activity
AM348_RS09465	COG1737	Transcriptional regulator
AM348_RS09475	COG1272	protein, Hemolysin III
AM348_RS09490	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM348_RS09515	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM348_RS09535	COG4942	peptidase
AM348_RS09550	COG0457	Tetratricopeptide repeat
AM348_RS09555	COG1649	PFAM Uncharacterised BCR, COG1649
AM348_RS09555	COG0726	polysaccharide deacetylase
AM348_RS09560	COG1215	transferase activity, transferring glycosyl groups
AM348_RS09570	COG3592	Divergent 4Fe-4S mono-cluster
AM348_RS09575	COG2388	GCN5-related N-acetyl-transferase
AM348_RS09580	COG0583	DNA-binding transcription factor activity
AM348_RS09585	COG0666	response to abiotic stimulus
AM348_RS09595	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM348_RS09600	COG1304	FMN binding
AM348_RS09610	COG0549	Belongs to the carbamate kinase family
AM348_RS09615	COG0402	S-adenosylhomocysteine deaminase activity
AM348_RS09640	COG0814	amino acid
AM348_RS09655	COG0183	Belongs to the thiolase family
AM348_RS09665	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS09670	COG2814	Major facilitator Superfamily
AM348_RS09680	COG1794	racemase activity, acting on amino acids and derivatives
AM348_RS09685	COG0583	DNA-binding transcription factor activity
AM348_RS09695	COG1609	Transcriptional regulator
AM348_RS09720	COG0667	Aldo Keto reductase
AM348_RS09730	COG0861	Integral membrane protein TerC family
AM348_RS09765	COG2165	general secretion pathway protein
AM348_RS09770	COG4795	General secretion pathway protein
AM348_RS09780	COG4967	type IV pilus modification protein PilV
AM348_RS09785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM348_RS09795	COG1074	ATP-dependent DNA helicase activity
AM348_RS09800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM348_RS09805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM348_RS09805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM348_RS09810	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM348_RS09830	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM348_RS09835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM348_RS09840	COG2166	iron-sulfur cluster assembly
AM348_RS09845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM348_RS09855	COG0583	DNA-binding transcription factor activity
AM348_RS09860	COG2363	Small membrane protein
AM348_RS09870	COG1349	DNA-binding transcription factor activity
AM348_RS09880	COG1070	Carbohydrate kinase
AM348_RS09890	COG0738	Major facilitator superfamily
AM348_RS09900	COG0235	Class ii aldolase
AM348_RS09905	COG1454	alcohol dehydrogenase
AM348_RS09920	COG1760	l-serine dehydratase
AM348_RS09925	COG0814	amino acid
AM348_RS09930	COG1611	Belongs to the LOG family
AM348_RS09945	COG3098	single-species biofilm formation
AM348_RS09950	COG0564	pseudouridine synthase activity
AM348_RS09955	COG0716	FMN binding
AM348_RS09965	COG2271	Major facilitator Superfamily
AM348_RS09970	COG4948	Mandelate Racemase Muconate Lactonizing
AM348_RS09975	COG4948	Mandelate Racemase Muconate Lactonizing
AM348_RS09980	COG1929	Belongs to the glycerate kinase type-1 family
AM348_RS09985	COG4999	Histidine kinase
AM348_RS09985	COG2205	protein histidine kinase activity
AM348_RS09985	COG3850	Histidine kinase
AM348_RS09985	COG3437	response regulator, receiver
AM348_RS09995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM348_RS10000	COG3956	TIGRFAM MazG family protein
AM348_RS10040	COG2190	(PTS) system
AM348_RS10040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM348_RS10040	COG1263	PTS System
AM348_RS10045	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AM348_RS10050	COG0602	queuosine metabolic process
AM348_RS10055	COG0720	synthase
AM348_RS10085	COG2234	aminopeptidase activity
AM348_RS10140	COG4942	peptidase
AM348_RS10140	COG1388	LysM domain
AM348_RS10155	COG0163	prenyltransferase activity
AM348_RS10160	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM348_RS10200	COG1538	Outer membrane efflux protein
AM348_RS10215	COG3300	MHYT domain
AM348_RS10215	COG5001	Diguanylate cyclase
AM348_RS10225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM348_RS10235	COG3300	MHYT domain
AM348_RS10235	COG5001	Diguanylate cyclase
AM348_RS10240	COG2200	EAL domain
AM348_RS10245	COG0840	transmembrane signaling receptor activity
AM348_RS10255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AM348_RS10265	COG0745	RESPONSE REGULATOR receiver
AM348_RS10295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM348_RS10300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM348_RS10305	COG1121	(ABC) transporter
AM348_RS10330	COG0309	Hydrogenase expression formation protein (HypE)
AM348_RS10335	COG0409	Hydrogenase expression formation protein
AM348_RS10340	COG0298	carbon dioxide binding
AM348_RS10345	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM348_RS10350	COG0375	protein maturation
AM348_RS10360	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM348_RS10365	COG0651	ATP synthesis coupled electron transport
AM348_RS10370	COG0650	Formate hydrogenlyase subunit 4
AM348_RS10375	COG3261	NADH dehydrogenase
AM348_RS10375	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM348_RS10380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM348_RS10385	COG3260	NADH ubiquinone oxidoreductase 20
AM348_RS10395	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM348_RS10405	COG2723	6-phospho-beta-galactosidase activity
AM348_RS10410	COG1263	PTS System
AM348_RS10410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM348_RS10415	COG1609	Transcriptional regulator
AM348_RS10420	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM348_RS10425	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AM348_RS10450	COG0517	IMP dehydrogenase activity
AM348_RS10450	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM348_RS10455	COG1349	DNA-binding transcription factor activity
AM348_RS10460	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM348_RS10465	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS10475	COG3732	PTS system glucitol sorbitol-specific
AM348_RS10480	COG3730	PTS system glucitol sorbitol-specific
AM348_RS10485	COG2951	lytic endotransglycosylase activity
AM348_RS10490	COG1546	Belongs to the CinA family
AM348_RS10510	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM348_RS10540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM348_RS10545	COG1238	metal cluster binding
AM348_RS10565	COG2814	Major facilitator Superfamily
AM348_RS10570	COG1566	PFAM secretion protein HlyD family protein
AM348_RS10575	COG1846	Transcriptional regulator
AM348_RS10585	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM348_RS10590	COG2814	Major facilitator Superfamily
AM348_RS10600	COG4176	ABC-type proline glycine betaine transport system permease component
AM348_RS10635	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM348_RS10665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM348_RS10670	COG0640	Transcriptional regulator
AM348_RS10675	COG0401	homolog of Blt101
AM348_RS10680	COG1652	LysM domain
AM348_RS10685	COG1802	Transcriptional regulator
AM348_RS10690	COG1113	amino acid transport
AM348_RS10700	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM348_RS10705	COG1012	belongs to the aldehyde dehydrogenase family
AM348_RS10710	COG0579	oxidoreductase
AM348_RS10755	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM348_RS10790	COG0438	transferase activity, transferring glycosyl groups
AM348_RS10795	COG0438	transferase activity, transferring glycosyl groups
AM348_RS10795	COG0297	glycogen (starch) synthase activity
AM348_RS10825	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM348_RS10830	COG1757	Na H antiporter
AM348_RS10835	COG2169	Transcriptional regulator
AM348_RS10850	COG3829	transcription factor binding
AM348_RS10855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM348_RS10860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM348_RS10865	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AM348_RS10870	COG2271	Major facilitator Superfamily
AM348_RS10885	COG2197	response regulator
AM348_RS10890	COG2198	Histidine kinase
AM348_RS10890	COG2205	protein histidine kinase activity
AM348_RS10890	COG0784	Response regulator, receiver
AM348_RS10890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM348_RS10910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM348_RS10915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM348_RS10920	COG3065	identical protein binding
AM348_RS10935	COG3962	Belongs to the TPP enzyme family
AM348_RS10945	COG0673	inositol 2-dehydrogenase activity
AM348_RS10960	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM348_RS10970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM348_RS10980	COG3718	enzyme involved in inositol metabolism
AM348_RS10985	COG1388	LysM domain
AM348_RS10985	COG1470	cell adhesion involved in biofilm formation
AM348_RS10995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM348_RS11020	COG2867	negative regulation of translational initiation
AM348_RS11035	COG0497	DNA recombination
AM348_RS11055	COG4536	flavin adenine dinucleotide binding
AM348_RS11060	COG4137	Cytochrome C assembly protein
AM348_RS11065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM348_RS11090	COG2885	chlorophyll binding
AM348_RS11095	COG2199	diguanylate cyclase activity
AM348_RS11110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM348_RS11115	COG0287	Prephenate dehydrogenase
AM348_RS11115	COG1605	Chorismate mutase
AM348_RS11120	COG0077	Prephenate dehydratase
AM348_RS11120	COG1605	Chorismate mutase
AM348_RS11130	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM348_RS11135	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM348_RS11150	COG0542	response to heat
AM348_RS11175	COG0477	Major facilitator Superfamily
AM348_RS11180	COG5544	Lipoprotein
AM348_RS11185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM348_RS11195	COG3148	PFAM DTW domain containing protein
AM348_RS11200	COG3118	belongs to the thioredoxin family
AM348_RS11210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM348_RS11230	COG0583	DNA-binding transcription factor activity
AM348_RS11235	COG0513	Belongs to the DEAD box helicase family
AM348_RS11245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM348_RS11255	COG1595	DNA-templated transcription, initiation
AM348_RS11265	COG3026	antisigma factor binding
AM348_RS11270	COG3086	response to oxidative stress
AM348_RS11280	COG0681	Belongs to the peptidase S26 family
AM348_RS11305	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM348_RS11315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM348_RS11320	COG1737	Transcriptional regulator
AM348_RS11325	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM348_RS11330	COG1263	PTS System
AM348_RS11330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM348_RS11335	COG0560	Phosphoserine phosphatase
AM348_RS11355	COG2205	protein histidine kinase activity
AM348_RS11360	COG3170	Tfp pilus assembly protein FimV
AM348_RS11365	COG2204	response regulator
AM348_RS11370	COG0347	Belongs to the P(II) protein family
AM348_RS11375	COG1017	nitric oxide dioxygenase activity
AM348_RS11375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM348_RS11405	COG4638	Rieske (2fe-2S)
AM348_RS11410	COG0583	DNA-binding transcription factor activity
AM348_RS11415	COG3539	Fimbrial protein
AM348_RS11420	COG3188	usher protein
AM348_RS11425	COG3121	Chaperone
AM348_RS11430	COG3539	Fimbrial protein
AM348_RS11435	COG2814	Major facilitator Superfamily
AM348_RS11440	COG3711	transcriptional antiterminator
AM348_RS11450	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM348_RS11450	COG0517	IMP dehydrogenase activity
AM348_RS11455	COG1069	ribulokinase activity
AM348_RS11465	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM348_RS11470	COG1129	ABC transporter
AM348_RS11480	COG3683	transport system, periplasmic component
AM348_RS11485	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM348_RS11510	COG0822	iron-sulfur transferase activity
AM348_RS11535	COG0633	Ferredoxin
AM348_RS11540	COG2975	iron-sulfur cluster assembly
AM348_RS11555	COG2897	thiosulfate sulfurtransferase activity
AM348_RS11560	COG2373	Large extracellular alpha-helical protein
AM348_RS11565	COG4953	penicillin-binding protein 1C
AM348_RS11595	COG2976	Protein conserved in bacteria
AM348_RS11625	COG1645	bacterial-type flagellum-dependent swarming motility
AM348_RS11630	COG1570	exodeoxyribonuclease VII activity
AM348_RS11635	COG0516	GMP reductase activity
AM348_RS11635	COG0517	IMP dehydrogenase activity
AM348_RS11645	COG0668	transmembrane transport
AM348_RS11655	COG2200	EAL domain
AM348_RS11670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM348_RS11680	COG2723	6-phospho-beta-galactosidase activity
AM348_RS11690	COG2233	PERMEase
AM348_RS11700	COG1393	Belongs to the ArsC family
AM348_RS11705	COG4783	chaperone-mediated protein folding
AM348_RS11710	COG0628	permease
AM348_RS11715	COG3366	ferrous iron transmembrane transporter activity
AM348_RS11720	COG0700	Nucleoside recognition
AM348_RS11725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM348_RS11730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM348_RS11735	COG2716	regulation of RNA biosynthetic process
AM348_RS11745	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM348_RS11755	COG2321	neutral zinc metallopeptidase
AM348_RS11765	COG0400	carboxylic ester hydrolase activity
AM348_RS11780	COG1393	Belongs to the ArsC family
AM348_RS11790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM348_RS11795	COG3850	Histidine kinase
AM348_RS11800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM348_RS11800	COG0493	'glutamate synthase
AM348_RS11810	COG5342	invasion associated locus B
AM348_RS11815	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM348_RS11840	COG4766	ethanolamine catabolic process
AM348_RS11845	COG4812	Cobalamin adenosyltransferase
AM348_RS11905	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM348_RS11910	COG2207	Transcriptional regulator
AM348_RS11925	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM348_RS11945	COG2837	iron assimilation
AM348_RS11955	COG4150	thiosulfate binding
AM348_RS11960	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM348_RS11965	COG4208	sulfate ABC transporter
AM348_RS11970	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM348_RS12035	COG3530	Putative quorum-sensing-regulated virulence factor
AM348_RS12040	COG0385	Bile acid
AM348_RS12045	COG0583	DNA-binding transcription factor activity
AM348_RS12065	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AM348_RS12070	COG2211	Major facilitator Superfamily
AM348_RS12075	COG0583	DNA-binding transcription factor activity
AM348_RS12105	COG3415	Transposase
AM348_RS12110	COG3415	Transposase
AM348_RS12130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM348_RS12145	COG0667	Aldo Keto reductase
AM348_RS12150	COG3961	Belongs to the TPP enzyme family
AM348_RS12170	COG3279	Response regulator of the LytR AlgR family
AM348_RS12175	COG3275	phosphorelay sensor kinase activity
AM348_RS12180	COG0436	Aminotransferase
AM348_RS12195	COG1560	Kdo2-lipid A biosynthetic process
AM348_RS12230	COG3122	Protein conserved in bacteria
AM348_RS12235	COG0840	transmembrane signaling receptor activity
AM348_RS12245	COG1446	asparaginase
AM348_RS12325	COG2116	formate transmembrane transporter activity
AM348_RS12335	COG2067	long-chain fatty acid transport protein
AM348_RS12345	COG3691	Protein conserved in bacteria
AM348_RS12360	COG2062	phosphohistidine phosphatase, SixA
AM348_RS12385	COG0730	response to heat
AM348_RS12390	COG3101	peptidyl-lysine hydroxylation
AM348_RS12405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM348_RS12425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM348_RS12435	COG0586	Pfam SNARE associated Golgi protein
AM348_RS12445	COG0285	dihydrofolate synthase activity
AM348_RS12450	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM348_RS12455	COG1286	toxin biosynthetic process
AM348_RS12460	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM348_RS12465	COG0163	prenyltransferase activity
AM348_RS12475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM348_RS12480	COG4215	(ABC) transporter
AM348_RS12490	COG4598	ABC transporter
AM348_RS12495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM348_RS12500	COG1090	epimerase
AM348_RS12505	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM348_RS12510	COG0625	glutathione transferase activity
AM348_RS12515	COG0625	glutathione transferase activity
AM348_RS12520	COG0622	Phosphoesterase
AM348_RS12530	COG1288	antiporter activity
AM348_RS12555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM348_RS12560	COG0471	metal ion transport
AM348_RS12560	COG0490	domain, Protein
AM348_RS12570	COG0436	Aminotransferase
AM348_RS12575	COG0583	DNA-binding transcription factor activity
AM348_RS12595	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AM348_RS12620	COG0839	Belongs to the complex I subunit 6 family
AM348_RS12630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM348_RS12635	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM348_RS12645	COG0835	chemotaxis
AM348_RS12645	COG0784	Response regulator, receiver
AM348_RS12655	COG2153	protein acetylation
AM348_RS12660	COG4575	ribosome binding
AM348_RS12665	COG1169	isochorismate synthase
AM348_RS12750	COG5464	transposase or invertase
AM348_RS12755	COG0247	lactate metabolic process
AM348_RS12765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM348_RS12770	COG2271	Major facilitator Superfamily
AM348_RS12775	COG0584	glycerophosphoryl diester phosphodiesterase
AM348_RS12780	COG0583	DNA-binding transcription factor activity
AM348_RS12785	COG2814	Major facilitator Superfamily
AM348_RS12790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM348_RS12825	COG0642	Histidine kinase
AM348_RS12825	COG2198	Histidine kinase
AM348_RS12835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM348_RS12845	COG1477	protein flavinylation
AM348_RS12850	COG2169	Transcriptional regulator
AM348_RS12850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM348_RS12855	COG3145	DNA-N1-methyladenine dioxygenase activity
AM348_RS12860	COG4615	Cyclic peptide transporter
AM348_RS12865	COG2239	Acts as a magnesium transporter
AM348_RS12870	COG0659	secondary active sulfate transmembrane transporter activity
AM348_RS12885	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM348_RS12885	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM348_RS12890	COG3062	negative regulation of establishment of protein localization
AM348_RS12900	COG0437	4 iron, 4 sulfur cluster binding
AM348_RS12905	COG0348	domain, Protein
AM348_RS12910	COG3043	anaerobic respiration
AM348_RS12915	COG3005	denitrification pathway
AM348_RS12920	COG4133	protoheme IX ABC transporter activity
AM348_RS12930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM348_RS12935	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM348_RS12945	COG1138	Cytochrome C-type biogenesis protein
AM348_RS12950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM348_RS12955	COG3088	subunit of a heme lyase
AM348_RS12955	COG4235	cytochrome complex assembly
AM348_RS12960	COG2197	response regulator
AM348_RS12995	COG1061	Type III restriction enzyme res subunit
AM348_RS13000	COG1187	pseudouridine synthase activity
AM348_RS13005	COG2814	Major facilitator Superfamily
AM348_RS13020	COG4172	Belongs to the ABC transporter superfamily
AM348_RS13025	COG4239	(ABC) transporter, permease
AM348_RS13030	COG4174	ABC transporter (Permease)
AM348_RS13035	COG4166	transmembrane transport
AM348_RS13040	COG2200	EAL domain
AM348_RS13045	COG0791	NLP P60 protein
AM348_RS13055	COG0671	phosphoesterase, PA-phosphatase related
AM348_RS13060	COG0523	cobalamin synthesis protein
AM348_RS13065	COG0246	Mannitol dehydrogenase
AM348_RS13070	COG1312	Catalyzes the dehydration of D-mannonate
AM348_RS13075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM348_RS13080	COG3005	denitrification pathway
AM348_RS13090	COG3381	protein complex oligomerization
AM348_RS13120	COG1105	Belongs to the carbohydrate kinase PfkB family
AM348_RS13125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM348_RS13125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM348_RS13125	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM348_RS13130	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM348_RS13145	COG0583	DNA-binding transcription factor activity
AM348_RS13155	COG2855	membrane
AM348_RS13165	COG0583	DNA-binding transcription factor activity
AM348_RS13175	COG0833	amino acid
AM348_RS13180	COG4771	TonB-dependent receptor
AM348_RS13200	COG2311	Membrane
AM348_RS13215	COG1129	ABC transporter
AM348_RS13230	COG2949	membrane
AM348_RS13240	COG1346	cytolysis
AM348_RS13255	COG2271	Major facilitator Superfamily
AM348_RS13270	COG0625	glutathione transferase activity
AM348_RS13275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM348_RS13280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM348_RS13295	COG0586	Pfam SNARE associated Golgi protein
AM348_RS13310	COG1686	Belongs to the peptidase S11 family
AM348_RS13315	COG0277	FAD linked oxidase domain protein
AM348_RS13320	COG1472	Belongs to the glycosyl hydrolase 3 family
AM348_RS13325	COG1732	Glycine betaine
AM348_RS13330	COG1174	glycine betaine transport
AM348_RS13335	COG1125	glycine betaine transport
AM348_RS13340	COG1174	glycine betaine transport
AM348_RS13355	COG0789	Transcriptional regulator
AM348_RS13360	COG3275	phosphorelay sensor kinase activity
AM348_RS13370	COG4807	Protein conserved in bacteria
AM348_RS13375	COG4808	Protein conserved in bacteria
AM348_RS13385	COG0489	protein tyrosine kinase activity
AM348_RS13400	COG3121	Chaperone
AM348_RS13405	COG3188	usher protein
AM348_RS13415	COG5455	response to cobalt ion
AM348_RS13425	COG0351	phosphomethylpyrimidine kinase
AM348_RS13430	COG2188	Transcriptional regulator
AM348_RS13435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM348_RS13440	COG1397	ADP-ribosylglycohydrolase
AM348_RS13445	COG2211	Major facilitator Superfamily
AM348_RS13450	COG1830	Aldolase
AM348_RS13460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM348_RS13465	COG4160	amino acid transport
AM348_RS13470	COG4215	(ABC) transporter
AM348_RS13475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM348_RS13480	COG1126	abc transporter atp-binding protein
AM348_RS13505	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM348_RS13510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM348_RS13515	COG0702	epimerase
AM348_RS13520	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AM348_RS13525	COG0028	Belongs to the TPP enzyme family
AM348_RS13535	COG4529	Protein conserved in bacteria
AM348_RS13540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM348_RS13550	COG2431	L-lysine efflux transmembrane transporter activity
AM348_RS13560	COG3593	DNA synthesis involved in DNA repair
AM348_RS13565	COG2990	Protein conserved in bacteria
AM348_RS13570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM348_RS13580	COG1278	Cold shock
AM348_RS13590	COG0542	response to heat
AM348_RS13605	COG0826	peptidase U32
AM348_RS13615	COG0745	RESPONSE REGULATOR receiver
AM348_RS13620	COG2205	protein histidine kinase activity
AM348_RS13645	COG0443	Heat shock 70 kDa protein
AM348_RS13650	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AM348_RS13655	COG5001	Diguanylate cyclase
AM348_RS13655	COG3447	MASE1 domain protein
AM348_RS13655	COG5002	protein histidine kinase activity
AM348_RS13675	COG2982	Protein involved in outer membrane biogenesis
AM348_RS13680	COG1253	flavin adenine dinucleotide binding
AM348_RS13695	COG0489	protein tyrosine kinase activity
AM348_RS13695	COG3206	protein involved in exopolysaccharide biosynthesis
AM348_RS13700	COG0463	Glycosyl transferase, family 2
AM348_RS13705	COG1045	serine acetyltransferase
AM348_RS13710	COG0438	transferase activity, transferring glycosyl groups
AM348_RS13720	COG1216	Glycosyl transferase, family 2
AM348_RS13725	COG0110	maltose O-acetyltransferase activity
AM348_RS13730	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AM348_RS13735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM348_RS13740	COG1051	belongs to the nudix hydrolase family
AM348_RS13745	COG0297	glycogen (starch) synthase activity
AM348_RS13755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM348_RS13760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM348_RS13765	COG2244	polysaccharide biosynthetic process
AM348_RS13770	COG2327	Polysaccharide pyruvyl transferase
AM348_RS13795	COG1088	dTDP-glucose 4,6-dehydratase activity
AM348_RS13840	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AM348_RS13855	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AM348_RS13875	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM348_RS13905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM348_RS13910	COG0583	DNA-binding transcription factor activity
AM348_RS13920	COG0531	amino acid
AM348_RS13925	COG2925	Exonuclease
AM348_RS13955	COG1289	transmembrane transporter activity
AM348_RS13990	COG4656	Part of a membrane complex involved in electron transport
AM348_RS14000	COG1012	belongs to the aldehyde dehydrogenase family
AM348_RS14010	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AM348_RS14180	COG1376	ErfK ybiS ycfS ynhG family protein
AM348_RS14185	COG3842	ATPase activity
AM348_RS14190	COG1178	ABC-type Fe3 transport system permease component
AM348_RS14195	COG1840	ABC-type Fe3 transport system, periplasmic component
AM348_RS14250	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM348_RS14285	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AM348_RS14290	COG1403	HNH endonuclease
AM348_RS14325	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM348_RS14330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM348_RS14335	COG1418	mRNA catabolic process
AM348_RS14340	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM348_RS14345	COG3727	T/G mismatch-specific endonuclease activity
AM348_RS14350	COG0697	spore germination
AM348_RS14355	COG2354	Protein conserved in bacteria
AM348_RS14360	COG5475	Uncharacterized small protein (DUF2158)
AM348_RS14420	COG2882	bacterial-type flagellum organization
AM348_RS14425	COG1157	protein secretion by the type III secretion system
AM348_RS14450	COG0425	Belongs to the sulfur carrier protein TusA family
AM348_RS14465	COG0366	Alpha amylase catalytic
AM348_RS14505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM348_RS14515	COG0765	amino acid transport
AM348_RS14520	COG1126	abc transporter atp-binding protein
AM348_RS14525	COG2197	response regulator
AM348_RS14535	COG2197	response regulator
AM348_RS14690	COG1403	HNH endonuclease
AM348_RS14720	COG3179	chitinase
AM348_RS14880	COG1305	Transglutaminase-like
AM348_RS14890	COG2608	mercury ion transmembrane transporter activity
AM348_RS14895	COG3012	SEC-C Motif Domain Protein
AM348_RS14895	COG3318	Belongs to the UPF0149 family
AM348_RS14900	COG0814	amino acid
AM348_RS14910	COG1528	Iron-storage protein
AM348_RS14925	COG0477	Major facilitator Superfamily
AM348_RS14935	COG1528	Iron-storage protein
AM348_RS14950	COG1879	ABC-type sugar transport system periplasmic component
AM348_RS14955	COG1129	ABC transporter
AM348_RS14960	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM348_RS14975	COG0589	response to stress
AM348_RS15010	COG0835	chemotaxis
AM348_RS15015	COG1301	dicarboxylic acid transport
AM348_RS15025	COG0840	transmembrane signaling receptor activity
AM348_RS15040	COG0745	RESPONSE REGULATOR receiver
AM348_RS15065	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AM348_RS15080	COG3102	Protein conserved in bacteria
AM348_RS15100	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM348_RS15105	COG1801	Protein of unknown function DUF72
AM348_RS15110	COG1335	isochorismatase
AM348_RS15120	COG0494	nUDIX hydrolase
AM348_RS15145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM348_RS15155	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM348_RS15160	COG0739	heme binding
AM348_RS15165	COG1560	Kdo2-lipid A biosynthetic process
AM348_RS15175	COG1737	Transcriptional regulator
AM348_RS15185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM348_RS15190	COG0129	dihydroxy-acid dehydratase activity
AM348_RS15195	COG0800	Aldolase
AM348_RS15205	COG3141	response to X-ray
AM348_RS15215	COG2979	Protein of unknown function (DUF533)
AM348_RS15220	COG1770	oligopeptidase
AM348_RS15225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM348_RS15230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM348_RS15240	COG2372	response to copper ion
AM348_RS15245	COG1276	copper resistance
AM348_RS15255	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM348_RS15275	COG3008	intermembrane lipid transfer
AM348_RS15280	COG2995	paraquat-inducible protein a
AM348_RS15285	COG1956	GAF domain-containing protein
AM348_RS15305	COG2814	Major facilitator Superfamily
AM348_RS15310	COG1414	Transcriptional regulator
AM348_RS15345	COG0768	penicillin binding
AM348_RS15350	COG2226	methyltransferase
AM348_RS15370	COG3716	PTS system mannose fructose sorbose family IID component
AM348_RS15375	COG3715	PTS system
AM348_RS15380	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM348_RS15380	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM348_RS15390	COG1253	flavin adenine dinucleotide binding
AM348_RS15395	COG2200	EAL domain
AM348_RS15400	COG1760	l-serine dehydratase
AM348_RS15420	COG0251	oxidation-reduction process
AM348_RS15425	COG1199	ATP-dependent helicase activity
AM348_RS15430	COG1214	PFAM Peptidase M22, glycoprotease
AM348_RS15435	COG3065	identical protein binding
AM348_RS15445	COG0318	PFAM AMP-dependent synthetase and ligase
AM348_RS15450	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM348_RS15455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM348_RS15460	COG4638	Rieske (2fe-2S)
AM348_RS15465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM348_RS15470	COG0473	3-isopropylmalate dehydrogenase activity
AM348_RS15475	COG0583	DNA-binding transcription factor activity
AM348_RS15485	COG2894	cell division
AM348_RS15500	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM348_RS15530	COG2719	SpoVR family
AM348_RS15540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM348_RS15550	COG1619	proteins homologs of microcin C7 resistance protein MccF
AM348_RS15580	COG0157	Belongs to the NadC ModD family
AM348_RS15585	COG0500	methyltransferase
AM348_RS15590	COG1120	ATPase activity
AM348_RS15595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM348_RS15600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM348_RS15615	COG1461	Dihydroxyacetone kinase
AM348_RS15620	COG2376	Dihydroxyacetone kinase
AM348_RS15625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM348_RS15650	COG0789	Transcriptional regulator
AM348_RS15655	COG2200	EAL domain
AM348_RS15700	COG0012	GTP binding
AM348_RS15715	COG0527	aspartate kinase activity
AM348_RS15720	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM348_RS15725	COG0076	glutamate decarboxylase activity
AM348_RS15730	COG0659	secondary active sulfate transmembrane transporter activity
AM348_RS15760	COG2890	protein-(glutamine-N5) methyltransferase activity
AM348_RS15780	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS15785	COG1309	transcriptional regulator
AM348_RS15795	COG0387	Pfam Sodium calcium exchanger
AM348_RS15800	COG4572	Cation transport regulator
AM348_RS15805	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AM348_RS15815	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM348_RS15820	COG3707	response regulator
AM348_RS15825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM348_RS15830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM348_RS15835	COG1116	anion transmembrane transporter activity
AM348_RS15840	COG2146	nitrite reductase [NAD(P)H] activity
AM348_RS15840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM348_RS15845	COG0243	molybdopterin cofactor binding
AM348_RS15850	COG4932	domain protein
AM348_RS15855	COG2197	response regulator
AM348_RS15860	COG3850	Histidine kinase
AM348_RS15870	COG2223	nitrite transmembrane transporter activity
AM348_RS15875	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM348_RS15880	COG1140	nitrate reductase beta subunit
AM348_RS15885	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM348_RS15890	COG2181	nitrate reductase activity
AM348_RS15910	COG0788	formyltetrahydrofolate deformylase activity
AM348_RS15920	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM348_RS15925	COG0745	RESPONSE REGULATOR receiver
AM348_RS15930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM348_RS15940	COG1435	thymidine kinase activity
AM348_RS15945	COG1012	belongs to the aldehyde dehydrogenase family
AM348_RS15945	COG1454	alcohol dehydrogenase
AM348_RS15950	COG2095	MarC family integral membrane protein
AM348_RS15990	COG0444	Belongs to the ABC transporter superfamily
AM348_RS16000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM348_RS16035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM348_RS16100	COG1484	DNA-dependent DNA replication
AM348_RS16175	COG3772	lysozyme
AM348_RS16350	COG2135	peptidase activity
AM348_RS16355	COG2350	Protein conserved in bacteria
AM348_RS16380	COG3047	cAMP biosynthetic process
AM348_RS16385	COG0217	transcriptional regulatory protein
AM348_RS16395	COG3706	GGDEF domain
AM348_RS16435	COG0009	L-threonylcarbamoyladenylate synthase
AM348_RS16440	COG1187	pseudouridine synthase activity
AM348_RS16450	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS16455	COG0616	signal peptide processing
AM348_RS16470	COG0583	DNA-binding transcription factor activity
AM348_RS16480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM348_RS16490	COG0671	phosphoesterase, PA-phosphatase related
AM348_RS16495	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM348_RS16500	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM348_RS16510	COG0023	Translation Initiation Factor
AM348_RS16520	COG1349	DNA-binding transcription factor activity
AM348_RS16535	COG5001	Diguanylate cyclase
AM348_RS16550	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM348_RS16550	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM348_RS16555	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM348_RS16575	COG4171	peptide transport system, permease
AM348_RS16600	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM348_RS16605	COG1842	Phage shock protein A
AM348_RS16615	COG1983	PspC domain protein
AM348_RS16630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM348_RS16635	COG3106	COG3106 Predicted ATPase
AM348_RS16650	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM348_RS16655	COG4948	Mandelate Racemase Muconate Lactonizing
AM348_RS16660	COG2866	Carboxypeptidase
AM348_RS16665	COG4166	transmembrane transport
AM348_RS16685	COG1349	DNA-binding transcription factor activity
AM348_RS16690	COG0346	lactoylglutathione lyase activity
AM348_RS16705	COG1064	alcohol dehydrogenase
AM348_RS16710	COG0668	transmembrane transport
AM348_RS16715	COG3182	Iron-regulated membrane protein
AM348_RS16730	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM348_RS16735	COG2840	Smr protein MutS2
AM348_RS16740	COG3706	GGDEF domain
AM348_RS16750	COG0840	transmembrane signaling receptor activity
AM348_RS16760	COG0513	Belongs to the DEAD box helicase family
AM348_RS16780	COG0589	response to stress
AM348_RS16790	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM348_RS16795	COG1013	pyruvate-flavodoxin oxidoreductase activity
AM348_RS16795	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AM348_RS16795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM348_RS16795	COG0674	pyruvate-flavodoxin oxidoreductase activity
AM348_RS16805	COG3042	response to heat
AM348_RS16810	COG3187	Heat shock protein
AM348_RS16815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM348_RS16825	COG2911	Protein conserved in bacteria
AM348_RS16835	COG3784	Protein of unknown function (DUF1318)
AM348_RS16850	COG1643	Atp-dependent helicase
AM348_RS16855	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM348_RS16860	COG1012	belongs to the aldehyde dehydrogenase family
AM348_RS16865	COG2755	lipolytic protein G-D-S-L family
AM348_RS16865	COG0657	acetylesterase activity
AM348_RS16870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM348_RS16875	COG3038	cytochrome b561
AM348_RS16880	COG0697	spore germination
AM348_RS16890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM348_RS16905	COG0582	viral genome integration into host DNA
AM348_RS16975	COG1475	DNA binding
AM348_RS16995	COG0840	transmembrane signaling receptor activity
AM348_RS17000	COG0583	DNA-binding transcription factor activity
AM348_RS17005	COG1227	inorganic diphosphatase activity
AM348_RS17010	COG5383	Protein conserved in bacteria
AM348_RS17025	COG2841	Protein conserved in bacteria
AM348_RS17035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM348_RS17040	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM348_RS17045	COG1275	C4-dicarboxylate transporter malic acid transport protein
AM348_RS17050	COG0500	methyltransferase
AM348_RS17060	COG0697	spore germination
AM348_RS17070	COG3135	benzoate transporter
AM348_RS17075	COG1396	sequence-specific DNA binding
AM348_RS17080	COG0826	peptidase U32
AM348_RS17095	COG1294	oxidase, subunit
AM348_RS17100	COG1271	oxidase subunit
AM348_RS17110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM348_RS17115	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM348_RS17120	COG3842	ATPase activity
AM348_RS17125	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM348_RS17130	COG1177	transmembrane transport
AM348_RS17140	COG2814	Major facilitator Superfamily
AM348_RS17145	COG2207	Transcriptional regulator
AM348_RS17175	COG0747	negative chemotaxis
AM348_RS17185	COG3238	Protein conserved in bacteria
AM348_RS17190	COG1247	-acetyltransferase
AM348_RS17200	COG2130	NADP-dependent
AM348_RS17205	COG4772	TonB-dependent receptor
AM348_RS17225	COG0840	transmembrane signaling receptor activity
AM348_RS17230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM348_RS17235	COG1473	amidohydrolase
AM348_RS17240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM348_RS17245	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AM348_RS17260	COG1126	abc transporter atp-binding protein
AM348_RS17265	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS17265	COG0604	alcohol dehydrogenase
AM348_RS17265	COG3321	synthase
AM348_RS17270	COG0583	DNA-binding transcription factor activity
AM348_RS17275	COG0625	glutathione transferase activity
AM348_RS17280	COG2271	Major facilitator Superfamily
AM348_RS17290	COG1609	Transcriptional regulator
AM348_RS17300	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AM348_RS17305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM348_RS17310	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AM348_RS17315	COG0384	phenazine biosynthesis protein PhzF
AM348_RS17320	COG2181	nitrate reductase activity
AM348_RS17325	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM348_RS17330	COG1140	nitrate reductase beta subunit
AM348_RS17335	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM348_RS17340	COG2223	nitrite transmembrane transporter activity
AM348_RS17375	COG0243	molybdopterin cofactor binding
AM348_RS17375	COG3383	formate dehydrogenase (NAD+) activity
AM348_RS17380	COG0243	molybdopterin cofactor binding
AM348_RS17380	COG3383	formate dehydrogenase (NAD+) activity
AM348_RS17385	COG0437	4 iron, 4 sulfur cluster binding
AM348_RS17390	COG2864	formate dehydrogenase
AM348_RS17400	COG3093	addiction module antidote protein HigA
AM348_RS17410	COG0488	(ABC) transporter
AM348_RS17425	COG1764	response to oxidative stress
AM348_RS17430	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS17435	COG2610	gluconate transmembrane transporter activity
AM348_RS17440	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM348_RS17450	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM348_RS17455	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM348_RS17465	COG4608	Belongs to the ABC transporter superfamily
AM348_RS17470	COG0444	Belongs to the ABC transporter superfamily
AM348_RS17475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM348_RS17480	COG0601	transmembrane transport
AM348_RS17485	COG0747	negative chemotaxis
AM348_RS17490	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AM348_RS17505	COG0840	transmembrane signaling receptor activity
AM348_RS17525	COG1649	PFAM Uncharacterised BCR, COG1649
AM348_RS17530	COG4628	conserved protein (DUF2132)
AM348_RS17550	COG2067	long-chain fatty acid transport protein
AM348_RS17555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM348_RS17565	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AM348_RS17645	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AM348_RS17645	COG3264	Mechanosensitive ion channel
AM348_RS17675	COG3781	membrane
AM348_RS17705	COG1012	belongs to the aldehyde dehydrogenase family
AM348_RS17710	COG0583	DNA-binding transcription factor activity
AM348_RS17725	COG1846	Transcriptional regulator
AM348_RS17740	COG0697	spore germination
AM348_RS17745	COG2814	Major facilitator Superfamily
AM348_RS17755	COG1122	ATPase activity
AM348_RS17785	COG3706	GGDEF domain
AM348_RS17800	COG4221	oxidoreductase activity
AM348_RS17805	COG1802	Transcriptional regulator
AM348_RS17815	COG0246	Mannitol dehydrogenase
AM348_RS17825	COG4948	Mandelate Racemase Muconate Lactonizing
AM348_RS17840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM348_RS17860	COG0437	4 iron, 4 sulfur cluster binding
AM348_RS17865	COG3302	dmso reductase anchor subunit
AM348_RS17870	COG3381	protein complex oligomerization
AM348_RS17880	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM348_RS17885	COG1940	carbohydrate kinase activity
AM348_RS17890	COG0583	DNA-binding transcription factor activity
AM348_RS17895	COG2814	Major facilitator Superfamily
AM348_RS17905	COG5002	protein histidine kinase activity
AM348_RS17910	COG0745	RESPONSE REGULATOR receiver
AM348_RS17925	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AM348_RS17935	COG3591	Belongs to the peptidase S1B family
AM348_RS17955	COG0628	permease
AM348_RS17960	COG2814	Major facilitator Superfamily
AM348_RS17965	COG0656	L-ascorbic acid biosynthetic process
AM348_RS17970	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM348_RS17975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM348_RS17985	COG0531	amino acid
AM348_RS17995	COG3136	membrane protein required for alginate biosynthesis
AM348_RS18000	COG0745	RESPONSE REGULATOR receiver
AM348_RS18005	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AM348_RS18015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM348_RS18030	COG2205	protein histidine kinase activity
AM348_RS18040	COG0114	fumarate hydratase activity
AM348_RS18045	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM348_RS18045	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM348_RS18055	COG5339	Protein conserved in bacteria
AM348_RS18060	COG1609	Transcriptional regulator
AM348_RS18065	COG1263	PTS System
AM348_RS18065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM348_RS18070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM348_RS18075	COG3706	GGDEF domain
AM348_RS18090	COG0673	inositol 2-dehydrogenase activity
AM348_RS18140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM348_RS18155	COG0625	glutathione transferase activity
AM348_RS18160	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AM348_RS18175	COG3895	Periplasmic Protein
AM348_RS18200	COG1566	PFAM secretion protein HlyD family protein
AM348_RS18215	COG4989	oxidoreductase activity
AM348_RS18220	COG3313	Fe-S protein
AM348_RS18225	COG1309	transcriptional regulator
AM348_RS18230	COG1902	pentaerythritol trinitrate reductase activity
AM348_RS18235	COG0346	lactoylglutathione lyase activity
AM348_RS18245	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM348_RS18250	COG0791	NLP P60 protein
AM348_RS18255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM348_RS18260	COG2814	Major facilitator Superfamily
AM348_RS18280	COG0583	DNA-binding transcription factor activity
AM348_RS18285	COG2814	Major facilitator Superfamily
AM348_RS18290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM348_RS18295	COG0307	riboflavin synthase, alpha
AM348_RS18305	COG0564	pseudouridine synthase activity
AM348_RS18320	COG0251	oxidation-reduction process
AM348_RS18340	COG3300	MHYT domain
AM348_RS18340	COG5001	Diguanylate cyclase
AM348_RS18345	COG3272	Protein of unknown function (DUF1722)
AM348_RS18355	COG0628	permease
AM348_RS18380	COG3188	usher protein
AM348_RS18405	COG2076	Multidrug Resistance protein
AM348_RS18415	COG0386	Belongs to the glutathione peroxidase family
AM348_RS18450	COG0583	DNA-binding transcription factor activity
AM348_RS18460	COG1120	ATPase activity
AM348_RS18465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM348_RS18470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM348_RS18475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM348_RS18490	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AM348_RS18500	COG1012	belongs to the aldehyde dehydrogenase family
AM348_RS18515	COG1113	amino acid transport
AM348_RS18530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM348_RS18545	COG0765	amino acid transport
AM348_RS18555	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AM348_RS18560	COG0437	4 iron, 4 sulfur cluster binding
AM348_RS18570	COG2414	aldehyde ferredoxin oxidoreductase
AM348_RS18575	COG0437	4 iron, 4 sulfur cluster binding
AM348_RS18610	COG1464	Belongs to the NlpA lipoprotein family
AM348_RS18615	COG2011	ABC-type metal ion transport system permease component
AM348_RS18640	COG1376	ErfK ybiS ycfS ynhG family protein
AM348_RS18655	COG0719	Fe-S assembly protein
AM348_RS18660	COG0396	ATPase activity
AM348_RS18665	COG0719	Fe-S assembly protein
AM348_RS18670	COG0316	Belongs to the HesB IscA family
AM348_RS18675	COG0583	DNA-binding transcription factor activity
AM348_RS18690	COG2050	protein possibly involved in aromatic compounds catabolism
AM348_RS18695	COG0277	FAD linked oxidase domain protein
AM348_RS18695	COG0247	lactate metabolic process
AM348_RS18700	COG0628	permease
AM348_RS18715	COG0738	Major facilitator superfamily
AM348_RS18720	COG2271	Major facilitator Superfamily
AM348_RS18735	COG4670	ketone body catabolic process
AM348_RS18740	COG1960	acyl-CoA dehydrogenase activity
AM348_RS18745	COG2207	Transcriptional regulator
AM348_RS18745	COG1917	Cupin 2, conserved barrel domain protein
AM348_RS18750	COG2086	electron transfer activity
AM348_RS18755	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AM348_RS18760	COG0644	oxidoreductase
AM348_RS18765	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM348_RS18770	COG0318	PFAM AMP-dependent synthetase and ligase
AM348_RS18775	COG0574	Belongs to the PEP-utilizing enzyme family
AM348_RS18775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM348_RS18785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM348_RS18790	COG4256	Hemin uptake protein
AM348_RS18795	COG4771	TonB-dependent receptor
AM348_RS18800	COG3720	iron ion transport
AM348_RS18805	COG4558	Periplasmic binding protein
AM348_RS18810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM348_RS18830	COG0791	NLP P60 protein
AM348_RS18840	COG0386	Belongs to the glutathione peroxidase family
AM348_RS18875	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AM348_RS18895	COG3137	Salt-induced outer membrane protein
AM348_RS18900	COG1105	Belongs to the carbohydrate kinase PfkB family
AM348_RS18905	COG3001	Fructosamine kinase
AM348_RS18915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM348_RS18920	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS18925	COG1988	membrane-bound metal-dependent
AM348_RS18930	COG1823	symporter activity
AM348_RS18945	COG1486	melibiose metabolic process
AM348_RS18950	COG2169	Transcriptional regulator
AM348_RS18950	COG1917	Cupin 2, conserved barrel domain protein
AM348_RS18955	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM348_RS18960	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM348_RS18965	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM348_RS18975	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM348_RS18985	COG0322	excinuclease ABC activity
AM348_RS18995	COG3678	ATP-independent chaperone mediated protein folding
AM348_RS19035	COG0708	Exodeoxyribonuclease III
AM348_RS19045	COG0398	Pfam SNARE associated Golgi protein
AM348_RS19050	COG0398	Pfam SNARE associated Golgi protein
AM348_RS19055	COG4134	Bacterial extracellular solute-binding protein
AM348_RS19060	COG4135	transport system, permease component
AM348_RS19065	COG4136	ATPase activity
AM348_RS19070	COG2897	thiosulfate sulfurtransferase activity
AM348_RS19075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM348_RS19080	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM348_RS19085	COG0494	nUDIX hydrolase
AM348_RS19100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM348_RS19115	COG0778	Nitroreductase
AM348_RS19125	COG0616	signal peptide processing
AM348_RS19135	COG0252	asparaginase activity
AM348_RS19140	COG1335	isochorismatase
AM348_RS19155	COG3139	Protein of unknown function (DUF1315)
AM348_RS19175	COG0656	L-ascorbic acid biosynthetic process
AM348_RS19190	COG3713	MltA-interacting MipA family protein
AM348_RS19195	COG2766	serine protein kinase
AM348_RS19205	COG2226	methyltransferase
AM348_RS19210	COG2199	diguanylate cyclase activity
AM348_RS19215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM348_RS19225	COG2207	Transcriptional regulator
AM348_RS19230	COG2807	transmembrane transport
AM348_RS19235	COG0504	CTP synthase activity
AM348_RS19240	COG3189	MarR family transcriptional regulator
AM348_RS19245	COG3042	response to heat
AM348_RS19250	COG2203	Gaf domain
AM348_RS19250	COG2199	diguanylate cyclase activity
AM348_RS19265	COG2261	transglycosylase associated protein
AM348_RS19270	COG3383	formate dehydrogenase (NAD+) activity
AM348_RS19285	COG3615	Tellurite resistance protein tehB
AM348_RS19295	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM348_RS19305	COG1124	(ABC) transporter
AM348_RS19315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM348_RS19320	COG0601	transmembrane transport
AM348_RS19325	COG0747	negative chemotaxis
AM348_RS19330	COG4771	TonB-dependent receptor
AM348_RS19340	COG2200	EAL domain
AM348_RS19365	COG0538	isocitrate dehydrogenase activity
AM348_RS19370	COG1187	pseudouridine synthase activity
AM348_RS19395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM348_RS19410	COG2850	peptidyl-arginine hydroxylation
AM348_RS19430	COG1177	transmembrane transport
AM348_RS19445	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM348_RS19455	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM348_RS19460	COG1136	(ABC) transporter
AM348_RS19465	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM348_RS19475	COG4763	Acyl-transferase
AM348_RS19480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM348_RS19485	COG1376	ErfK ybiS ycfS ynhG family protein
AM348_RS19485	COG1388	LysM domain
AM348_RS19495	COG1309	transcriptional regulator
AM348_RS19505	COG3134	Outer membrane lipoprotein
AM348_RS19510	COG1252	NADH dehydrogenase
AM348_RS19535	COG5633	Lipoprotein
AM348_RS19540	COG0537	adenosine 5'-monophosphoramidase activity
AM348_RS19545	COG4773	Receptor
AM348_RS19550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM348_RS19555	COG3327	negative regulation of DNA-templated transcription, initiation
AM348_RS19560	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM348_RS19565	COG0183	Belongs to the thiolase family
AM348_RS19570	COG2050	protein possibly involved in aromatic compounds catabolism
AM348_RS19575	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM348_RS19580	COG1024	Enoyl-CoA hydratase
AM348_RS19585	COG1024	Enoyl-CoA hydratase
AM348_RS19590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM348_RS19595	COG2151	metal-sulfur cluster biosynthetic enzyme
AM348_RS19600	COG3396	Phenylacetate-CoA oxygenase
AM348_RS19605	COG3460	Phenylacetate-CoA oxygenase
AM348_RS19610	COG3396	Phenylacetate-CoA oxygenase
AM348_RS19615	COG2030	dehydratase
AM348_RS19615	COG1012	belongs to the aldehyde dehydrogenase family
AM348_RS19625	COG0534	Mate efflux family protein
AM348_RS19645	COG0583	DNA-binding transcription factor activity
AM348_RS19665	COG1595	DNA-templated transcription, initiation
AM348_RS19670	COG3712	iron ion homeostasis
AM348_RS19675	COG4772	TonB-dependent receptor
AM348_RS19680	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AM348_RS19685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM348_RS19690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM348_RS19695	COG1120	ATPase activity
AM348_RS19705	COG2814	Major facilitator Superfamily
AM348_RS19725	COG0110	maltose O-acetyltransferase activity
AM348_RS19730	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM348_RS19735	COG1609	Transcriptional regulator
AM348_RS19740	COG2223	nitrite transmembrane transporter activity
AM348_RS19765	COG0477	Major facilitator Superfamily
AM348_RS19770	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM348_RS19785	COG0084	hydrolase, TatD family'
AM348_RS19790	COG0470	DNA polymerase III
AM348_RS19800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM348_RS19805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM348_RS19810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM348_RS19845	COG1399	metal-binding, possibly nucleic acid-binding protein
AM348_RS19855	COG0564	pseudouridine synthase activity
AM348_RS19865	COG1530	ribonuclease E activity
AM348_RS19870	COG0583	DNA-binding transcription factor activity
AM348_RS19875	COG2814	Major facilitator Superfamily
AM348_RS19905	COG4786	Flagellar basal body rod
AM348_RS19910	COG4787	bacterial-type flagellum-dependent cell motility
AM348_RS19925	COG1558	bacterial-type flagellum-dependent cell motility
AM348_RS19965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM348_RS20005	COG3038	cytochrome b561
AM348_RS20020	COG1560	Kdo2-lipid A biosynthetic process
AM348_RS20030	COG2199	diguanylate cyclase activity
AM348_RS20040	COG5645	(Lipo)protein
AM348_RS20060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM348_RS20115	COG3381	protein complex oligomerization
AM348_RS20140	COG1702	phosphate starvation-inducible protein PhoH
AM348_RS20160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM348_RS20170	COG0506	proline dehydrogenase activity
AM348_RS20170	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM348_RS20170	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM348_RS20175	COG3755	Protein conserved in bacteria
AM348_RS20180	COG1309	transcriptional regulator
AM348_RS20190	COG3729	General stress protein
AM348_RS20210	COG0640	Transcriptional regulator
AM348_RS20220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM348_RS20225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM348_RS20225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM348_RS20275	COG0813	purine-nucleoside phosphorylase activity
AM348_RS20290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM348_RS20295	COG1120	ATPase activity
AM348_RS20310	COG2857	Cytochrome c1
AM348_RS20310	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AM348_RS20475	COG0670	Belongs to the BI1 family
AM348_RS20500	COG1832	CoA-binding protein
AM348_RS20515	COG0210	DNA helicase
AM348_RS20520	COG3304	Inner membrane component domain
AM348_RS20525	COG1289	transmembrane transporter activity
AM348_RS20530	COG3070	regulator of competence-specific genes
AM348_RS20550	COG1067	ATP-dependent peptidase activity
AM348_RS20560	COG3130	regulation of translation
AM348_RS20565	COG3009	Protein conserved in bacteria
AM348_RS20570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM348_RS20570	COG3008	intermembrane lipid transfer
AM348_RS20575	COG2995	paraquat-inducible protein a
AM348_RS20580	COG0488	(ABC) transporter
AM348_RS20590	COG3217	Mosc domain protein beta barrel domain protein
AM348_RS20590	COG0633	Ferredoxin
AM348_RS20610	COG0431	NADPH-dependent FMN reductase
AM348_RS20615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM348_RS20625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM348_RS20635	COG0308	aminopeptidase N
AM348_RS20655	COG1448	Aminotransferase
AM348_RS20660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM348_RS20665	COG3108	Peptidase M15
AM348_RS20675	COG2989	Protein conserved in bacteria
AM348_RS20690	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AM348_RS20700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM348_RS20705	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM348_RS20710	COG3173	Aminoglycoside phosphotransferase
AM348_RS20725	COG3214	Protein conserved in bacteria
AM348_RS20740	COG2333	competence protein COMEC
AM348_RS20740	COG0658	competence protein
AM348_RS20745	COG0776	regulation of translation
AM348_RS20750	COG0539	negative regulation of cytoplasmic translation
AM348_RS20770	COG2323	membrane
AM348_RS20775	COG1944	ATP diphosphatase activity
AM348_RS20780	COG2116	formate transmembrane transporter activity
AM348_RS20785	COG1882	Formate acetyltransferase
AM348_RS20790	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM348_RS20800	COG0531	amino acid
AM348_RS20810	COG1335	isochorismatase
AM348_RS20815	COG3302	dmso reductase anchor subunit
AM348_RS20820	COG0437	4 iron, 4 sulfur cluster binding
AM348_RS20825	COG0243	molybdopterin cofactor binding
AM348_RS20835	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM348_RS20845	COG1674	ftsk spoiiie
AM348_RS20845	COG1178	ABC-type Fe3 transport system permease component
AM348_RS20860	COG0492	ferredoxin-NADP+ reductase activity
AM348_RS20865	COG4988	ABC transporter
AM348_RS20870	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM348_RS20885	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AM348_RS20890	COG0583	DNA-binding transcription factor activity
AM348_RS20900	COG1335	isochorismatase
AM348_RS20910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM348_RS20920	COG1177	transmembrane transport
AM348_RS20925	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM348_RS20930	COG3842	ATPase activity
AM348_RS20935	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM348_RS20980	COG3226	Transcriptional regulator
AM348_RS20985	COG0738	Major facilitator superfamily
AM348_RS20990	COG0561	phosphatase activity
AM348_RS21000	COG2814	Major facilitator Superfamily
AM348_RS21005	COG0671	phosphoesterase, PA-phosphatase related
AM348_RS21010	COG1349	DNA-binding transcription factor activity
AM348_RS21015	COG1686	Belongs to the peptidase S11 family
AM348_RS21020	COG0625	glutathione transferase activity
AM348_RS21025	COG2133	pyrroloquinoline quinone binding
AM348_RS21035	COG0583	DNA-binding transcription factor activity
AM348_RS21040	COG0058	SHG alpha-glucan phosphorylase activity
AM348_RS21065	COG0747	negative chemotaxis
AM348_RS21075	COG1446	asparaginase
AM348_RS21090	COG0303	'Molybdopterin
AM348_RS21095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM348_RS21100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM348_RS21105	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM348_RS21110	COG1882	Formate acetyltransferase
AM348_RS21115	COG0561	phosphatase activity
AM348_RS21125	COG0488	(ABC) transporter
AM348_RS21130	COG1376	ErfK ybiS ycfS ynhG family protein
AM348_RS21135	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM348_RS21150	COG2194	sulfuric ester hydrolase activity
AM348_RS21155	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM348_RS21170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM348_RS21175	COG0765	amino acid transport
AM348_RS21180	COG1126	abc transporter atp-binding protein
AM348_RS21185	COG0668	transmembrane transport
AM348_RS21200	COG4774	siderophore transport
AM348_RS21210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM348_RS21220	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM348_RS21225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM348_RS21235	COG0471	metal ion transport
AM348_RS21245	COG2188	Transcriptional regulator
AM348_RS21250	COG0513	Belongs to the DEAD box helicase family
AM348_RS21255	COG1309	transcriptional regulator
AM348_RS21265	COG1131	(ABC) transporter
AM348_RS21270	COG0842	Transport permease protein
AM348_RS21275	COG0842	Transport permease protein
AM348_RS21285	COG3568	Endonuclease Exonuclease Phosphatase
AM348_RS21290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM348_RS21295	COG0392	lysyltransferase activity
AM348_RS21300	COG0670	Belongs to the BI1 family
AM348_RS21305	COG0314	molybdopterin synthase activity
AM348_RS21310	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM348_RS21320	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM348_RS21355	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM348_RS21380	COG1881	PFAM PEBP family protein
AM348_RS21410	COG4677	pectinesterase activity
AM348_RS21420	COG0561	phosphatase activity
AM348_RS21430	COG4149	molybdate abc transporter
AM348_RS21435	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM348_RS21450	COG3585	molybdate ion transport
AM348_RS21450	COG2005	Transcriptional regulator
AM348_RS21455	COG1119	ATPase activity
AM348_RS21460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM348_RS21465	COG1085	galactose-1-phosphate uridylyltransferase
AM348_RS21475	COG2017	converts alpha-aldose to the beta-anomer
AM348_RS21485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM348_RS21495	COG1230	cation diffusion facilitator family transporter
AM348_RS21500	COG3201	nicotinamide mononucleotide transporter
AM348_RS21535	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM348_RS21540	COG2885	chlorophyll binding
AM348_RS21550	COG3064	Membrane
AM348_RS21555	COG0848	biopolymer transport protein
AM348_RS21560	COG0811	peptide transport
AM348_RS21565	COG0824	Thioesterase
AM348_RS21575	COG3790	cyd operon protein YbgE
AM348_RS21580	COG4890	Cyd operon protein YbgT
AM348_RS21585	COG1294	oxidase, subunit
AM348_RS21590	COG1271	oxidase subunit
AM348_RS21595	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AM348_RS21605	COG4865	methylaspartate mutase activity
AM348_RS21610	COG3799	methylaspartate ammonia-lyase activity
AM348_RS21625	COG1301	dicarboxylic acid transport
AM348_RS21635	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM348_RS21635	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM348_RS21645	COG0583	DNA-binding transcription factor activity
AM348_RS21650	COG1648	precorrin-2 dehydrogenase activity
AM348_RS21650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM348_RS21660	COG3395	kinase activity
AM348_RS21665	COG0235	Class ii aldolase
AM348_RS21670	COG1349	DNA-binding transcription factor activity
AM348_RS21675	COG3622	Belongs to the hyi family
AM348_RS21680	COG3246	L-lysine catabolic process to acetate
AM348_RS21700	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM348_RS21710	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM348_RS21715	COG0567	Dehydrogenase, E1 component
AM348_RS21720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM348_RS21725	COG1053	succinate dehydrogenase
AM348_RS21730	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM348_RS21735	COG2009	succinate dehydrogenase
AM348_RS21750	COG3157	Type VI secretion system effector, Hcp
AM348_RS21765	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
AM348_RS21770	COG3180	Ammonia monooxygenase
AM348_RS21800	COG1984	allophanate hydrolase subunit 2
AM348_RS21805	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM348_RS21810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM348_RS21820	COG5464	transposase or invertase
AM348_RS21830	COG3272	Protein of unknown function (DUF1722)
AM348_RS21860	COG2205	protein histidine kinase activity
AM348_RS21865	COG0745	RESPONSE REGULATOR receiver
AM348_RS21870	COG0033	Phosphoglucomutase
AM348_RS21875	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AM348_RS21880	COG0596	Alpha beta hydrolase
AM348_RS21890	COG0716	FMN binding
AM348_RS21900	COG0735	belongs to the Fur family
AM348_RS21905	COG0583	DNA-binding transcription factor activity
AM348_RS21910	COG1053	succinate dehydrogenase
AM348_RS21945	COG2190	(PTS) system
AM348_RS21945	COG1263	PTS System
AM348_RS21945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM348_RS21955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM348_RS21960	COG1846	Transcriptional regulator
AM348_RS21960	COG1940	carbohydrate kinase activity
AM348_RS21965	COG0647	UMP catabolic process
AM348_RS21975	COG0367	asparagine synthase
AM348_RS22015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM348_RS22025	COG1702	phosphate starvation-inducible protein PhoH
AM348_RS22035	COG4535	Mg2 and Co2 transporter CorC
AM348_RS22050	COG0765	amino acid transport
AM348_RS22055	COG0765	amino acid transport
AM348_RS22060	COG1126	abc transporter atp-binding protein
AM348_RS22070	COG2888	peptidyl-tyrosine sulfation
AM348_RS22085	COG1466	dna polymerase III delta subunit
AM348_RS22095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM348_RS22105	COG0799	negative regulation of ribosome biogenesis
AM348_RS22115	COG0768	penicillin binding
AM348_RS22120	COG0772	Belongs to the SEDS family
AM348_RS22125	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM348_RS22130	COG1686	Belongs to the peptidase S11 family
AM348_RS22155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM348_RS22175	COG3069	C4-dicarboxylate transmembrane transporter activity
AM348_RS22180	COG4565	transcriptional regulatory protein
AM348_RS22185	COG3290	protein histidine kinase activity
AM348_RS22190	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AM348_RS22200	COG2301	Belongs to the HpcH HpaI aldolase family
AM348_RS22205	COG3051	citrate lyase alpha subunit
AM348_RS22220	COG0471	metal ion transport
AM348_RS22225	COG3719	Belongs to the RNase T2 family
AM348_RS22240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM348_RS22260	COG0243	molybdopterin cofactor binding
AM348_RS22270	COG3634	alkyl hydroperoxide reductase activity
AM348_RS22280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM348_RS22285	COG0583	DNA-binding transcription factor activity
AM348_RS22290	COG3969	phosphoadenosine phosphosulfate
AM348_RS22295	COG1475	DNA binding
AM348_RS22300	COG0436	Aminotransferase
AM348_RS22305	COG0371	Dehydrogenase
AM348_RS22315	COG2879	small protein
AM348_RS22320	COG1966	Carbon starvation protein
AM348_RS22335	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS22340	COG1535	isochorismatase
AM348_RS22340	COG3433	isochorismatase activity
AM348_RS22345	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM348_RS22350	COG1169	isochorismate synthase
AM348_RS22355	COG4592	Periplasmic binding protein
AM348_RS22365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM348_RS22370	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM348_RS22375	COG1120	ATPase activity
AM348_RS22380	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AM348_RS22385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM348_RS22385	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM348_RS22390	COG3251	PFAM MbtH domain protein
AM348_RS22395	COG2382	esterase
AM348_RS22405	COG4771	TonB-dependent receptor
AM348_RS22410	COG2977	Belongs to the P-Pant transferase superfamily
AM348_RS22415	COG3958	Transketolase
AM348_RS22420	COG3959	Transketolase, thiamine diphosphate binding domain
AM348_RS22425	COG2390	Transcriptional regulator
AM348_RS22430	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM348_RS22435	COG1879	ABC-type sugar transport system periplasmic component
AM348_RS22445	COG1129	ABC transporter
AM348_RS22450	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM348_RS22455	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS22460	COG1028	Short-chain dehydrogenase reductase Sdr
AM348_RS22495	COG2315	Protein conserved in bacteria
AM348_RS22505	COG0668	transmembrane transport
AM348_RS22525	COG2211	Major facilitator Superfamily
AM348_RS22530	COG1113	amino acid transport
AM348_RS22555	COG3300	MHYT domain
AM348_RS22555	COG5001	Diguanylate cyclase
AM348_RS22570	COG3059	membrane
AM348_RS22580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM348_RS22585	COG2207	Transcriptional regulator
AM348_RS22590	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM348_RS22595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM348_RS22600	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM348_RS22605	COG1538	Outer membrane efflux protein
AM348_RS22610	COG0745	RESPONSE REGULATOR receiver
AM348_RS22615	COG5002	protein histidine kinase activity
AM348_RS22630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM348_RS22630	COG0321	lipoyl(octanoyl) transferase activity
AM348_RS22635	COG0243	molybdopterin cofactor binding
AM348_RS22640	COG3005	denitrification pathway
AM348_RS22660	COG3005	denitrification pathway
AM348_RS22665	COG0745	RESPONSE REGULATOR receiver
AM348_RS22670	COG1879	ABC-type sugar transport system periplasmic component
AM348_RS22675	COG2205	protein histidine kinase activity
AM348_RS22675	COG2198	Histidine kinase
AM348_RS22675	COG0784	Response regulator, receiver
AM348_RS22740	COG2501	S4 domain
AM348_RS22745	COG1988	membrane-bound metal-dependent
AM348_RS22755	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM348_RS22775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM348_RS22780	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM348_RS22790	COG2011	ABC-type metal ion transport system permease component
AM348_RS22800	COG1464	Belongs to the NlpA lipoprotein family
AM348_RS22805	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM348_RS22810	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM348_RS22815	COG4181	ATPase activity
AM348_RS22820	COG2755	lipolytic protein G-D-S-L family
AM348_RS22825	COG0300	oxidoreductase activity
AM348_RS22830	COG3118	belongs to the thioredoxin family
AM348_RS22835	COG0390	transport system, permease component
AM348_RS22840	COG4619	ABC transporter
AM348_RS22845	COG0330	HflC and HflK could
AM348_RS22850	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM348_RS22870	COG4771	TonB-dependent receptor
AM348_RS22875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM348_RS22885	COG3721	Heme iron utilization protein
AM348_RS22895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM348_RS22905	COG2217	Heavy metal translocating P-type atpase
AM348_RS22910	COG3735	TraB family
AM348_RS22915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM348_RS22930	COG2223	nitrite transmembrane transporter activity
AM348_RS22935	COG4651	solute:proton antiporter activity
AM348_RS22935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM348_RS22940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM348_RS23000	COG2832	Protein of unknown function (DUF454)
AM348_RS23005	COG3923	Primosomal replication protein n
AM348_RS23020	COG3264	Mechanosensitive ion channel
AM348_RS23020	COG1196	nuclear chromosome segregation
AM348_RS23025	COG1309	transcriptional regulator
AM348_RS23030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM348_RS23035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM348_RS23050	COG0110	maltose O-acetyltransferase activity
AM348_RS23070	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM348_RS23075	COG5507	3-demethylubiquinone-9 3-methyltransferase
AM348_RS23080	COG2364	Membrane
AM348_RS23085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM348_RS23105	COG3695	enzyme binding
AM348_RS23110	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AM348_RS23115	COG1946	Acyl-CoA thioesterase
AM348_RS23120	COG0004	ammonium transporteR
AM348_RS23125	COG0347	Belongs to the P(II) protein family
AM348_RS23135	COG1132	(ABC) transporter
AM348_RS23140	COG1132	(ABC) transporter
AM348_RS23145	COG1522	sequence-specific DNA binding
AM348_RS23165	COG4533	DNA binding
AM348_RS23175	COG0824	Thioesterase
AM348_RS23180	COG1555	photosystem II stabilization
AM348_RS23185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM348_RS23190	COG0776	regulation of translation
AM348_RS23195	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM348_RS23215	COG0271	Belongs to the BolA IbaG family
AM348_RS23220	COG3056	Lipoprotein
AM348_RS23225	COG2223	nitrite transmembrane transporter activity
AM348_RS23230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM348_RS23235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM348_RS23240	COG1845	cytochrome c oxidase, subunit III
AM348_RS23245	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM348_RS23255	COG2814	Major facilitator Superfamily
AM348_RS23290	COG0142	geranyltranstransferase activity
AM348_RS23300	COG0667	Aldo Keto reductase
AM348_RS23305	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM348_RS23310	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM348_RS23325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM348_RS23325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM348_RS23335	COG4238	major outer membrane lipoprotein
AM348_RS23355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM348_RS23360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM348_RS23365	COG1862	Preprotein translocase
AM348_RS23375	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AM348_RS23385	COG0450	alkyl hydroperoxide reductase
AM348_RS23390	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AM348_RS23400	COG1335	isochorismatase
AM348_RS23405	COG0583	DNA-binding transcription factor activity
AM348_RS23410	COG0366	Alpha amylase catalytic
AM348_RS23430	COG5002	protein histidine kinase activity
AM348_RS23440	COG0420	3'-5' exonuclease activity
AM348_RS23445	COG0419	ATPase involved in DNA repair
AM348_RS23460	COG3121	Chaperone
AM348_RS23470	COG2814	Major facilitator Superfamily
AM348_RS23475	COG1940	carbohydrate kinase activity
AM348_RS23490	COG4126	flavin adenine dinucleotide binding
AM348_RS23510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM348_RS23515	COG3706	GGDEF domain
AM348_RS23525	COG1785	Belongs to the alkaline phosphatase family
AM348_RS23540	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM348_RS23560	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM348_RS23565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM348_RS23570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM348_RS23575	COG3468	outer membrane autotransporter barrel domain protein
AM348_RS23580	COG0113	porphobilinogen synthase activity
AM348_RS23585	COG2175	clavaminate synthase activity
AM348_RS23590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM348_RS23595	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AM348_RS23600	COG4521	taurine ABC transporter
AM348_RS23615	COG2271	Major facilitator Superfamily
AM348_RS23620	COG1840	ABC-type Fe3 transport system, periplasmic component
AM348_RS23630	COG3842	ATPase activity
AM348_RS23635	COG2040	homocysteine