locus-tag	class	description
CFE2614_RS00010	COG0592	DNA-directed DNA polymerase activity
CFE2614_RS00025	COG0561	phosphatase activity
CFE2614_RS00035	COG0823	Involved in the tonB-independent uptake of proteins
CFE2614_RS00040	COG5645	(Lipo)protein
CFE2614_RS00060	COG2149	membrane
CFE2614_RS00070	COG0641	radical SAM
CFE2614_RS00080	COG2610	gluconate transmembrane transporter activity
CFE2614_RS00085	COG0583	DNA-binding transcription factor activity
CFE2614_RS00095	COG2814	Major facilitator Superfamily
CFE2614_RS00115	COG0028	Belongs to the TPP enzyme family
CFE2614_RS00120	COG0440	acetolactate synthase activity
CFE2614_RS00125	COG1349	DNA-binding transcription factor activity
CFE2614_RS00135	COG0738	Major facilitator superfamily
CFE2614_RS00145	COG2197	response regulator
CFE2614_RS00175	COG3620	sequence-specific DNA binding
CFE2614_RS00185	COG2723	6-phospho-beta-galactosidase activity
CFE2614_RS00210	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFE2614_RS00210	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFE2614_RS00215	COG3715	PTS system
CFE2614_RS00220	COG3716	PTS system mannose fructose sorbose family IID component
CFE2614_RS00235	COG5464	transposase or invertase
CFE2614_RS00240	COG1464	Belongs to the NlpA lipoprotein family
CFE2614_RS00245	COG0697	spore germination
CFE2614_RS00255	COG0604	alcohol dehydrogenase
CFE2614_RS00260	COG0583	DNA-binding transcription factor activity
CFE2614_RS00280	COG2771	luxR family
CFE2614_RS00365	COG0582	viral genome integration into host DNA
CFE2614_RS00375	COG2211	Major facilitator Superfamily
CFE2614_RS00380	COG1501	Belongs to the glycosyl hydrolase 31 family
CFE2614_RS00385	COG3711	transcriptional antiterminator
CFE2614_RS00390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS00390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFE2614_RS00390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS00395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS00400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS00400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS00410	COG0191	fructose-bisphosphate aldolase activity
CFE2614_RS00420	COG2982	Protein involved in outer membrane biogenesis
CFE2614_RS00425	COG2233	PERMEase
CFE2614_RS00430	COG0786	glutamate:sodium symporter activity
CFE2614_RS00435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFE2614_RS00440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFE2614_RS00445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFE2614_RS00465	COG2860	membrane
CFE2614_RS00470	COG1561	YicC-like family, N-terminal region
CFE2614_RS00500	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFE2614_RS00515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFE2614_RS00530	COG1519	Transferase
CFE2614_RS00535	COG0438	transferase activity, transferring glycosyl groups
CFE2614_RS00540	COG0515	serine threonine protein kinase
CFE2614_RS00545	COG1442	glycosyl transferase family 8
CFE2614_RS00550	COG1442	glycosyl transferase family 8
CFE2614_RS00560	COG0859	PFAM glycosyl transferase family 9
CFE2614_RS00565	COG1215	transferase activity, transferring glycosyl groups
CFE2614_RS00570	COG3307	-O-antigen
CFE2614_RS00580	COG0859	PFAM glycosyl transferase family 9
CFE2614_RS00590	COG0156	8-amino-7-oxononanoate synthase activity
CFE2614_RS00600	COG1216	Glycosyl transferase, family 2
CFE2614_RS00605	COG2861	carbohydrate metabolic process
CFE2614_RS00610	COG4942	peptidase
CFE2614_RS00620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFE2614_RS00625	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFE2614_RS00640	COG1045	serine acetyltransferase
CFE2614_RS00645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CFE2614_RS00650	COG2271	Major facilitator Superfamily
CFE2614_RS00660	COG2186	Transcriptional regulator
CFE2614_RS00680	COG3722	fumarate hydratase activity
CFE2614_RS00690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFE2614_RS00690	COG2213	PTS system mannitol-specific
CFE2614_RS00705	COG1566	PFAM secretion protein HlyD family protein
CFE2614_RS00710	COG0625	glutathione transferase activity
CFE2614_RS00720	COG3276	selenocysteine insertion sequence binding
CFE2614_RS00725	COG1454	alcohol dehydrogenase
CFE2614_RS00730	COG1012	belongs to the aldehyde dehydrogenase family
CFE2614_RS00740	COG1566	PFAM secretion protein HlyD family protein
CFE2614_RS00745	COG0583	DNA-binding transcription factor activity
CFE2614_RS00750	COG3713	MltA-interacting MipA family protein
CFE2614_RS00760	COG2211	Major facilitator Superfamily
CFE2614_RS00765	COG1917	Cupin 2, conserved barrel domain protein
CFE2614_RS00765	COG4977	sequence-specific DNA binding
CFE2614_RS00770	COG0235	Class ii aldolase
CFE2614_RS00775	COG3623	hexulose-6-phosphate isomerase
CFE2614_RS00780	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CFE2614_RS00785	COG1070	Carbohydrate kinase
CFE2614_RS00790	COG2271	Major facilitator Superfamily
CFE2614_RS00800	COG2731	YhcH YjgK YiaL family protein
CFE2614_RS00810	COG1414	Transcriptional regulator
CFE2614_RS00815	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CFE2614_RS00820	COG3977	Valine--pyruvate aminotransferase
CFE2614_RS00830	COG0366	Alpha amylase catalytic
CFE2614_RS00835	COG2992	FlgJ-related protein
CFE2614_RS00840	COG2207	Transcriptional regulator
CFE2614_RS00840	COG1609	Transcriptional regulator
CFE2614_RS00850	COG1070	Carbohydrate kinase
CFE2614_RS00855	COG4682	membrane
CFE2614_RS00860	COG3274	enterobacterial common antigen metabolic process
CFE2614_RS00885	COG1278	Cold shock
CFE2614_RS00890	COG2944	sequence-specific DNA binding
CFE2614_RS00905	COG2814	Major facilitator Superfamily
CFE2614_RS00910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFE2614_RS00920	COG1609	Transcriptional regulator
CFE2614_RS00925	COG2885	chlorophyll binding
CFE2614_RS00930	COG0243	molybdopterin cofactor binding
CFE2614_RS00935	COG0456	acetyltransferase
CFE2614_RS00940	COG2818	Glycosylase
CFE2614_RS00945	COG5571	outer membrane autotransporter
CFE2614_RS00950	COG2223	nitrite transmembrane transporter activity
CFE2614_RS00975	COG0747	negative chemotaxis
CFE2614_RS00985	COG0601	transmembrane transport
CFE2614_RS00990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFE2614_RS00995	COG0444	Belongs to the ABC transporter superfamily
CFE2614_RS01000	COG4608	Belongs to the ABC transporter superfamily
CFE2614_RS01005	COG2204	response regulator
CFE2614_RS01010	COG0814	amino acid
CFE2614_RS01015	COG0626	cystathionine gamma-synthase activity
CFE2614_RS01025	COG2199	diguanylate cyclase activity
CFE2614_RS01025	COG2200	EAL domain
CFE2614_RS01040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFE2614_RS01045	COG2200	EAL domain
CFE2614_RS01050	COG2982	Protein involved in outer membrane biogenesis
CFE2614_RS01055	COG0477	Major facilitator Superfamily
CFE2614_RS01060	COG1295	ribonuclease BN
CFE2614_RS01065	COG0583	DNA-binding transcription factor activity
CFE2614_RS01070	COG1028	Short-chain dehydrogenase reductase Sdr
CFE2614_RS01080	COG2200	EAL domain
CFE2614_RS01085	COG2197	response regulator
CFE2614_RS01095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFE2614_RS01110	COG1858	cytochrome C peroxidase
CFE2614_RS01120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFE2614_RS01125	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CFE2614_RS01130	COG0339	signal peptide processing
CFE2614_RS01145	COG1959	2 iron, 2 sulfur cluster binding
CFE2614_RS01155	COG0589	response to stress
CFE2614_RS01165	COG0306	phosphate transporter
CFE2614_RS01170	COG2081	HI0933 family
CFE2614_RS01250	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFE2614_RS01280	COG0739	heme binding
CFE2614_RS01290	COG2132	Multicopper oxidase
CFE2614_RS01295	COG3667	copper resistance
CFE2614_RS01300	COG2372	response to copper ion
CFE2614_RS01305	COG1276	copper resistance
CFE2614_RS01310	COG0745	RESPONSE REGULATOR receiver
CFE2614_RS01315	COG2205	protein histidine kinase activity
CFE2614_RS01330	COG3436	PFAM IS66 Orf2 family protein
CFE2614_RS01335	COG4372	Transposase
CFE2614_RS01340	COG2239	Acts as a magnesium transporter
CFE2614_RS01345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFE2614_RS01350	COG1129	ABC transporter
CFE2614_RS01350	COG0842	Transport permease protein
CFE2614_RS01355	COG0842	Transport permease protein
CFE2614_RS01375	COG2091	lysine biosynthetic process via aminoadipic acid
CFE2614_RS01380	COG0628	permease
CFE2614_RS01385	COG0477	Major facilitator Superfamily
CFE2614_RS01395	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CFE2614_RS01410	COG3714	YhhN family
CFE2614_RS01435	COG3776	membrane
CFE2614_RS01440	COG0742	ribosomal rna small subunit methyltransferase
CFE2614_RS01445	COG0552	protein localization to endoplasmic reticulum
CFE2614_RS01450	COG2884	Cell division ATP-binding protein ftsE
CFE2614_RS01455	COG2177	Part of the ABC transporter FtsEX involved in
CFE2614_RS01480	COG0683	leucine binding
CFE2614_RS01490	COG4177	L-phenylalanine transmembrane transporter activity
CFE2614_RS01495	COG0411	ABC transporter
CFE2614_RS01530	COG0584	glycerophosphoryl diester phosphodiesterase
CFE2614_RS01540	COG0405	Gamma-glutamyltransferase
CFE2614_RS01545	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CFE2614_RS01560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFE2614_RS01570	COG1247	-acetyltransferase
CFE2614_RS01575	COG0673	inositol 2-dehydrogenase activity
CFE2614_RS01580	COG1741	Belongs to the pirin family
CFE2614_RS01585	COG1609	Transcriptional regulator
CFE2614_RS01590	COG3265	gluconokinase activity
CFE2614_RS01595	COG2610	gluconate transmembrane transporter activity
CFE2614_RS01610	COG2095	MarC family integral membrane protein
CFE2614_RS01615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFE2614_RS01640	COG0058	SHG alpha-glucan phosphorylase activity
CFE2614_RS01645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CFE2614_RS01660	COG1349	DNA-binding transcription factor activity
CFE2614_RS01670	COG0058	SHG alpha-glucan phosphorylase activity
CFE2614_RS01675	COG1640	4-alpha-glucanotransferase
CFE2614_RS01680	COG2610	gluconate transmembrane transporter activity
CFE2614_RS01690	COG1040	competence protein
CFE2614_RS01715	COG1918	ferrous iron import across plasma membrane
CFE2614_RS01720	COG2183	response to ionizing radiation
CFE2614_RS01725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFE2614_RS01755	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CFE2614_RS01765	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CFE2614_RS01770	COG1011	Hydrolase
CFE2614_RS01780	COG0494	nUDIX hydrolase
CFE2614_RS01785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFE2614_RS01790	COG4972	Pilus assembly protein
CFE2614_RS01795	COG3166	PFAM Fimbrial assembly family protein
CFE2614_RS01810	COG4796	Type ii and iii secretion system protein
CFE2614_RS01825	COG3266	domain, Protein
CFE2614_RS01830	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CFE2614_RS01835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CFE2614_RS01845	COG0180	Tryptophanyl-tRNA synthetase
CFE2614_RS01850	COG2188	Transcriptional regulator
CFE2614_RS01860	COG3457	Alanine racemase
CFE2614_RS01865	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CFE2614_RS01870	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CFE2614_RS01885	COG0626	cystathionine gamma-synthase activity
CFE2614_RS01905	COG2146	nitrite reductase [NAD(P)H] activity
CFE2614_RS01910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFE2614_RS01935	COG0512	Glutamine amidotransferase of anthranilate synthase
CFE2614_RS01940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFE2614_RS01945	COG1289	transmembrane transporter activity
CFE2614_RS01955	COG1765	OsmC-like protein
CFE2614_RS01960	COG3954	Phosphoribulokinase
CFE2614_RS01970	COG0429	hydrolase of the alpha beta-hydrolase fold
CFE2614_RS01980	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFE2614_RS01990	COG0488	(ABC) transporter
CFE2614_RS02005	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CFE2614_RS02010	COG1047	Peptidyl-prolyl cis-trans
CFE2614_RS02020	COG0545	Peptidyl-prolyl cis-trans isomerase
CFE2614_RS02025	COG2964	Protein conserved in bacteria
CFE2614_RS02050	COG0049	tRNA binding
CFE2614_RS02080	COG0051	transcription antitermination factor activity, RNA binding
CFE2614_RS02090	COG0088	Forms part of the polypeptide exit tunnel
CFE2614_RS02105	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFE2614_RS02180	COG0200	Binds to the 23S rRNA
CFE2614_RS02185	COG0201	protein transport
CFE2614_RS02200	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFE2614_RS02225	COG0789	Transcriptional regulator
CFE2614_RS02230	COG3036	rescue of stalled ribosome
CFE2614_RS02240	COG0569	domain protein
CFE2614_RS02260	COG0758	DNA mediated transformation
CFE2614_RS02270	COG0551	DNA topoisomerase type I activity
CFE2614_RS02290	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CFE2614_RS02335	COG1126	abc transporter atp-binding protein
CFE2614_RS02340	COG0765	amino acid transport
CFE2614_RS02345	COG4597	amino acid ABC transporter
CFE2614_RS02350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFE2614_RS02360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFE2614_RS02365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFE2614_RS02370	COG1309	transcriptional regulator
CFE2614_RS02380	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CFE2614_RS02460	COG4145	pantothenate transmembrane transporter activity
CFE2614_RS02465	COG3924	membrane
CFE2614_RS02470	COG0439	Biotin carboxylase
CFE2614_RS02475	COG0511	ligase activity, forming carbon-carbon bonds
CFE2614_RS02490	COG0604	alcohol dehydrogenase
CFE2614_RS02495	COG2200	EAL domain
CFE2614_RS02495	COG2199	diguanylate cyclase activity
CFE2614_RS02505	COG1077	Cell shape determining protein MreB Mrl
CFE2614_RS02510	COG1792	Involved in formation and maintenance of cell shape
CFE2614_RS02515	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CFE2614_RS02530	COG3164	Protein of unknown function
CFE2614_RS02535	COG0312	modulator of DNA gyrase
CFE2614_RS02540	COG0583	DNA-binding transcription factor activity
CFE2614_RS02560	COG2732	(Barnase) inhibitor
CFE2614_RS02585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFE2614_RS02590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFE2614_RS02595	COG3105	Protein conserved in bacteria
CFE2614_RS02600	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CFE2614_RS02620	COG0625	glutathione transferase activity
CFE2614_RS02625	COG2969	positive regulation of protein catabolic process
CFE2614_RS02630	COG3069	C4-dicarboxylate transmembrane transporter activity
CFE2614_RS02655	COG2731	YhcH YjgK YiaL family protein
CFE2614_RS02660	COG0402	S-adenosylhomocysteine deaminase activity
CFE2614_RS02665	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CFE2614_RS02670	COG4804	nuclease activity
CFE2614_RS02675	COG0493	'glutamate synthase
CFE2614_RS02680	COG0070	glutamate synthase
CFE2614_RS02680	COG0069	glutamate synthase activity
CFE2614_RS02680	COG0067	glutamate synthase
CFE2614_RS02685	COG1242	4 iron, 4 sulfur cluster binding
CFE2614_RS02690	COG0784	Response regulator, receiver
CFE2614_RS02690	COG5002	protein histidine kinase activity
CFE2614_RS02690	COG2198	Histidine kinase
CFE2614_RS02695	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CFE2614_RS02705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFE2614_RS02720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFE2614_RS02730	COG1137	ATPase activity
CFE2614_RS02735	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CFE2614_RS02740	COG3117	lipopolysaccharide transmembrane transporter activity
CFE2614_RS02745	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CFE2614_RS02755	COG0530	calcium, potassium:sodium antiporter activity
CFE2614_RS02760	COG1127	ABC transporter
CFE2614_RS02765	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CFE2614_RS02770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CFE2614_RS02775	COG2854	intermembrane phospholipid transfer
CFE2614_RS02780	COG3113	response to antibiotic
CFE2614_RS02785	COG5007	Belongs to the BolA IbaG family
CFE2614_RS02795	COG3423	Transcriptional regulator
CFE2614_RS02800	COG0142	geranyltranstransferase activity
CFE2614_RS02805	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFE2614_RS02810	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFE2614_RS02815	COG0697	spore germination
CFE2614_RS02825	COG2027	D-alanyl-D-alanine carboxypeptidase
CFE2614_RS02845	COG1534	Rna-binding protein
CFE2614_RS02855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFE2614_RS02860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFE2614_RS02870	COG3069	C4-dicarboxylate transmembrane transporter activity
CFE2614_RS02875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFE2614_RS02880	COG0583	DNA-binding transcription factor activity
CFE2614_RS02885	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CFE2614_RS02910	COG0195	Participates in both transcription termination and antitermination
CFE2614_RS02915	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFE2614_RS02920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFE2614_RS02950	COG0513	Belongs to the DEAD box helicase family
CFE2614_RS02955	COG0814	amino acid
CFE2614_RS02960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFE2614_RS02965	COG0826	peptidase U32
CFE2614_RS02970	COG0826	peptidase U32
CFE2614_RS02975	COG3154	lipid carrier protein
CFE2614_RS02980	COG3153	acetyltransferase
CFE2614_RS02995	COG0702	epimerase
CFE2614_RS03000	COG2823	Periplasmic or secreted lipoprotein
CFE2614_RS03020	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFE2614_RS03030	COG2222	sugar isomerase
CFE2614_RS03035	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFE2614_RS03040	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFE2614_RS03045	COG3716	PTS system mannose fructose sorbose family IID component
CFE2614_RS03055	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFE2614_RS03065	COG1349	DNA-binding transcription factor activity
CFE2614_RS03070	COG1349	DNA-binding transcription factor activity
CFE2614_RS03075	COG1940	carbohydrate kinase activity
CFE2614_RS03080	COG0673	inositol 2-dehydrogenase activity
CFE2614_RS03085	COG3842	ATPase activity
CFE2614_RS03090	COG0395	ABC-type sugar transport system, permease component
CFE2614_RS03095	COG1175	transmembrane transport
CFE2614_RS03105	COG2721	sulfolactate sulfo-lyase activity
CFE2614_RS03115	COG2271	Major facilitator Superfamily
CFE2614_RS03125	COG2084	Dehydrogenase
CFE2614_RS03130	COG1929	Belongs to the glycerate kinase type-1 family
CFE2614_RS03180	COG0583	DNA-binding transcription factor activity
CFE2614_RS03200	COG1882	Formate acetyltransferase
CFE2614_RS03205	COG0251	oxidation-reduction process
CFE2614_RS03210	COG1760	l-serine dehydratase
CFE2614_RS03215	COG0814	amino acid
CFE2614_RS03230	COG1741	Belongs to the pirin family
CFE2614_RS03235	COG0583	DNA-binding transcription factor activity
CFE2614_RS03240	COG3152	Membrane
CFE2614_RS03255	COG0435	Glutathione S-transferase
CFE2614_RS03260	COG2259	Doxx family
CFE2614_RS03270	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CFE2614_RS03275	COG4575	ribosome binding
CFE2614_RS03280	COG1422	Protein of unknown function (DUF1090)
CFE2614_RS03290	COG0586	Pfam SNARE associated Golgi protein
CFE2614_RS03295	COG2186	Transcriptional regulator
CFE2614_RS03300	COG2271	Major facilitator Superfamily
CFE2614_RS03310	COG2721	sulfolactate sulfo-lyase activity
CFE2614_RS03330	COG0673	inositol 2-dehydrogenase activity
CFE2614_RS03335	COG1451	nucleotide metabolic process
CFE2614_RS03345	COG1902	pentaerythritol trinitrate reductase activity
CFE2614_RS03345	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFE2614_RS03350	COG3408	Glycogen debranching enzyme
CFE2614_RS03350	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CFE2614_RS03360	COG0531	amino acid
CFE2614_RS03365	COG2731	YhcH YjgK YiaL family protein
CFE2614_RS03370	COG3250	beta-galactosidase activity
CFE2614_RS03375	COG1609	Transcriptional regulator
CFE2614_RS03380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFE2614_RS03390	COG0840	transmembrane signaling receptor activity
CFE2614_RS03395	COG1695	Transcriptional regulator
CFE2614_RS03400	COG2375	cellular response to nickel ion
CFE2614_RS03410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFE2614_RS03480	COG4974	Belongs to the 'phage' integrase family
CFE2614_RS03515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CFE2614_RS03550	COG4695	Portal protein
CFE2614_RS03700	COG4771	TonB-dependent receptor
CFE2614_RS03705	COG3391	amine dehydrogenase activity
CFE2614_RS03715	COG0358	DNA primase activity
CFE2614_RS03720	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFE2614_RS03725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFE2614_RS03730	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFE2614_RS03740	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CFE2614_RS03770	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CFE2614_RS03775	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CFE2614_RS03790	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFE2614_RS03805	COG4991	sh3 domain protein
CFE2614_RS03810	COG3025	triphosphatase activity
CFE2614_RS03825	COG2268	Band 7 protein
CFE2614_RS03830	COG1585	Membrane protein implicated in regulation of membrane protease activity
CFE2614_RS03870	COG3384	dioxygenase
CFE2614_RS03875	COG0754	glutathionylspermidine amidase activity
CFE2614_RS03890	COG0494	nUDIX hydrolase
CFE2614_RS03895	COG3151	Protein conserved in bacteria
CFE2614_RS03900	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CFE2614_RS03905	COG3150	esterase
CFE2614_RS03910	COG0187	DNA topoisomerase II activity
CFE2614_RS03915	COG4977	sequence-specific DNA binding
CFE2614_RS03915	COG1917	Cupin 2, conserved barrel domain protein
CFE2614_RS03925	COG2211	Major facilitator Superfamily
CFE2614_RS03930	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CFE2614_RS03935	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CFE2614_RS03940	COG2249	NAD(P)H dehydrogenase (quinone) activity
CFE2614_RS03955	COG3111	PFAM Bacterial OB fold (BOF) protein
CFE2614_RS03975	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFE2614_RS03990	COG0471	metal ion transport
CFE2614_RS03995	COG0656	L-ascorbic acid biosynthetic process
CFE2614_RS04000	COG1979	alcohol dehydrogenase
CFE2614_RS04005	COG2207	Transcriptional regulator
CFE2614_RS04010	COG0586	Pfam SNARE associated Golgi protein
CFE2614_RS04015	COG0626	cystathionine gamma-synthase activity
CFE2614_RS04025	COG0848	biopolymer transport protein
CFE2614_RS04045	COG0667	Aldo Keto reductase
CFE2614_RS04055	COG0840	transmembrane signaling receptor activity
CFE2614_RS04065	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CFE2614_RS04070	COG0437	4 iron, 4 sulfur cluster binding
CFE2614_RS04075	COG5557	Pfam Polysulphide reductase, NrfD
CFE2614_RS04080	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CFE2614_RS04085	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CFE2614_RS04090	COG1773	rubredoxin
CFE2614_RS04100	COG0298	carbon dioxide binding
CFE2614_RS04105	COG0625	glutathione transferase activity
CFE2614_RS04110	COG0243	molybdopterin cofactor binding
CFE2614_RS04115	COG0754	glutathionylspermidine amidase activity
CFE2614_RS04125	COG1811	Na channel or pump
CFE2614_RS04130	COG1982	Orn Lys Arg decarboxylase major
CFE2614_RS04135	COG2211	Major facilitator Superfamily
CFE2614_RS04150	COG1194	a g-specific adenine glycosylase
CFE2614_RS04160	COG3171	Protein conserved in bacteria
CFE2614_RS04170	COG0252	asparaginase activity
CFE2614_RS04175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFE2614_RS04190	COG0762	integral membrane protein
CFE2614_RS04195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CFE2614_RS04200	COG2805	Type II/IV secretion system protein
CFE2614_RS04215	COG0189	ligase activity
CFE2614_RS04220	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CFE2614_RS04225	COG2356	endonuclease I
CFE2614_RS04230	COG3091	SprT-like family
CFE2614_RS04235	COG2814	Major facilitator Superfamily
CFE2614_RS04260	COG1166	arginine decarboxylase activity
CFE2614_RS04270	COG0501	Belongs to the peptidase M48B family
CFE2614_RS04275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CFE2614_RS04280	COG1122	ATPase activity
CFE2614_RS04285	COG1122	ATPase activity
CFE2614_RS04315	COG0191	fructose-bisphosphate aldolase activity
CFE2614_RS04375	COG2003	Belongs to the UPF0758 family
CFE2614_RS04410	COG5489	Protein of unknown function (DUF736)
CFE2614_RS04445	COG1192	Involved in chromosome partitioning
CFE2614_RS04460	COG4959	Type IV secretory pathway protease TraF
CFE2614_RS04485	COG2076	Multidrug Resistance protein
CFE2614_RS04510	COG0583	DNA-binding transcription factor activity
CFE2614_RS04530	COG4962	Type ii secretion system protein e
CFE2614_RS04535	COG3838	Conjugal transfer protein Trbc
CFE2614_RS04545	COG3451	type IV secretory pathway VirB4
CFE2614_RS04560	COG3846	protein secretion by the type IV secretion system
CFE2614_RS04575	COG2948	multi-organism process
CFE2614_RS04585	COG0668	transmembrane transport
CFE2614_RS04590	COG1279	arginine transmembrane transporter activity
CFE2614_RS04595	COG2968	Membrane
CFE2614_RS04600	COG0583	DNA-binding transcription factor activity
CFE2614_RS04605	COG0427	acetyl-CoA hydrolase
CFE2614_RS04610	COG1024	Enoyl-CoA hydratase
CFE2614_RS04615	COG1703	isobutyryl-CoA mutase activity
CFE2614_RS04620	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFE2614_RS04620	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFE2614_RS04635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFE2614_RS04640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFE2614_RS04660	COG0006	proline dipeptidase activity
CFE2614_RS04665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFE2614_RS04670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFE2614_RS04690	COG1028	Short-chain dehydrogenase reductase Sdr
CFE2614_RS04695	COG2723	6-phospho-beta-galactosidase activity
CFE2614_RS04700	COG1737	Transcriptional regulator
CFE2614_RS04710	COG1272	protein, Hemolysin III
CFE2614_RS04720	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CFE2614_RS04745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFE2614_RS04765	COG4942	peptidase
CFE2614_RS04875	COG1649	PFAM Uncharacterised BCR, COG1649
CFE2614_RS04875	COG0726	polysaccharide deacetylase
CFE2614_RS04880	COG1215	transferase activity, transferring glycosyl groups
CFE2614_RS04890	COG3592	Divergent 4Fe-4S mono-cluster
CFE2614_RS04895	COG2388	GCN5-related N-acetyl-transferase
CFE2614_RS04900	COG0583	DNA-binding transcription factor activity
CFE2614_RS04905	COG0666	response to abiotic stimulus
CFE2614_RS04915	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFE2614_RS04920	COG1304	FMN binding
CFE2614_RS04930	COG0549	Belongs to the carbamate kinase family
CFE2614_RS04935	COG0402	S-adenosylhomocysteine deaminase activity
CFE2614_RS04955	COG0814	amino acid
CFE2614_RS04970	COG0183	Belongs to the thiolase family
CFE2614_RS04980	COG1028	Short-chain dehydrogenase reductase Sdr
CFE2614_RS04985	COG2814	Major facilitator Superfamily
CFE2614_RS04990	COG5464	transposase or invertase
CFE2614_RS05000	COG1794	racemase activity, acting on amino acids and derivatives
CFE2614_RS05005	COG0583	DNA-binding transcription factor activity
CFE2614_RS05015	COG1609	Transcriptional regulator
CFE2614_RS05045	COG0667	Aldo Keto reductase
CFE2614_RS05055	COG0861	Integral membrane protein TerC family
CFE2614_RS05085	COG2165	general secretion pathway protein
CFE2614_RS05090	COG4795	General secretion pathway protein
CFE2614_RS05100	COG4967	type IV pilus modification protein PilV
CFE2614_RS05105	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CFE2614_RS05115	COG1074	ATP-dependent DNA helicase activity
CFE2614_RS05120	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFE2614_RS05125	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CFE2614_RS05125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFE2614_RS05130	COG0860	N-Acetylmuramoyl-L-alanine amidase
CFE2614_RS05160	COG3121	Chaperone
CFE2614_RS05165	COG3188	usher protein
CFE2614_RS05200	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CFE2614_RS05205	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CFE2614_RS05210	COG2166	iron-sulfur cluster assembly
CFE2614_RS05215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFE2614_RS05225	COG0583	DNA-binding transcription factor activity
CFE2614_RS05230	COG2363	Small membrane protein
CFE2614_RS05240	COG1349	DNA-binding transcription factor activity
CFE2614_RS05250	COG1070	Carbohydrate kinase
CFE2614_RS05260	COG1129	ABC transporter
CFE2614_RS05265	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFE2614_RS05275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFE2614_RS05285	COG0235	Class ii aldolase
CFE2614_RS05290	COG1454	alcohol dehydrogenase
CFE2614_RS05300	COG1760	l-serine dehydratase
CFE2614_RS05305	COG0814	amino acid
CFE2614_RS05310	COG1611	Belongs to the LOG family
CFE2614_RS05325	COG3098	single-species biofilm formation
CFE2614_RS05330	COG0564	pseudouridine synthase activity
CFE2614_RS05335	COG0716	FMN binding
CFE2614_RS05340	COG2271	Major facilitator Superfamily
CFE2614_RS05345	COG4948	Mandelate Racemase Muconate Lactonizing
CFE2614_RS05350	COG4948	Mandelate Racemase Muconate Lactonizing
CFE2614_RS05355	COG1929	Belongs to the glycerate kinase type-1 family
CFE2614_RS05360	COG3437	response regulator, receiver
CFE2614_RS05360	COG3850	Histidine kinase
CFE2614_RS05360	COG2205	protein histidine kinase activity
CFE2614_RS05360	COG4999	Histidine kinase
CFE2614_RS05370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFE2614_RS05375	COG3956	TIGRFAM MazG family protein
CFE2614_RS05390	COG1737	Transcriptional regulator
CFE2614_RS05395	COG2190	(PTS) system
CFE2614_RS05395	COG1263	PTS System
CFE2614_RS05395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFE2614_RS05400	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CFE2614_RS05405	COG0602	queuosine metabolic process
CFE2614_RS05410	COG0720	synthase
CFE2614_RS05435	COG2234	aminopeptidase activity
CFE2614_RS05490	COG4942	peptidase
CFE2614_RS05490	COG1388	LysM domain
CFE2614_RS05505	COG0163	prenyltransferase activity
CFE2614_RS05510	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CFE2614_RS05535	COG0628	permease
CFE2614_RS05540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFE2614_RS05560	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CFE2614_RS05565	COG1882	Formate acetyltransferase
CFE2614_RS05580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFE2614_RS05585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFE2614_RS05590	COG1121	(ABC) transporter
CFE2614_RS05610	COG0309	Hydrogenase expression formation protein (HypE)
CFE2614_RS05615	COG0409	Hydrogenase expression formation protein
CFE2614_RS05620	COG0298	carbon dioxide binding
CFE2614_RS05625	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFE2614_RS05630	COG0375	protein maturation
CFE2614_RS05640	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CFE2614_RS05645	COG0651	ATP synthesis coupled electron transport
CFE2614_RS05650	COG0650	Formate hydrogenlyase subunit 4
CFE2614_RS05655	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CFE2614_RS05655	COG3261	NADH dehydrogenase
CFE2614_RS05660	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFE2614_RS05665	COG3260	NADH ubiquinone oxidoreductase 20
CFE2614_RS05675	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CFE2614_RS05685	COG2723	6-phospho-beta-galactosidase activity
CFE2614_RS05695	COG1609	Transcriptional regulator
CFE2614_RS05700	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CFE2614_RS05705	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CFE2614_RS05725	COG0517	IMP dehydrogenase activity
CFE2614_RS05725	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CFE2614_RS05730	COG1349	DNA-binding transcription factor activity
CFE2614_RS05735	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFE2614_RS05740	COG1028	Short-chain dehydrogenase reductase Sdr
CFE2614_RS05750	COG3732	PTS system glucitol sorbitol-specific
CFE2614_RS05755	COG3730	PTS system glucitol sorbitol-specific
CFE2614_RS05760	COG2951	lytic endotransglycosylase activity
CFE2614_RS05765	COG1546	Belongs to the CinA family
CFE2614_RS05785	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CFE2614_RS05815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFE2614_RS05820	COG1238	metal cluster binding
CFE2614_RS05840	COG2814	Major facilitator Superfamily
CFE2614_RS05845	COG1566	PFAM secretion protein HlyD family protein
CFE2614_RS05850	COG1846	Transcriptional regulator
CFE2614_RS05860	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CFE2614_RS05865	COG2814	Major facilitator Superfamily
CFE2614_RS05875	COG4176	ABC-type proline glycine betaine transport system permease component
CFE2614_RS05915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFE2614_RS05945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFE2614_RS05950	COG0640	Transcriptional regulator
CFE2614_RS05955	COG0401	homolog of Blt101
CFE2614_RS05960	COG1652	LysM domain
CFE2614_RS05965	COG1802	Transcriptional regulator
CFE2614_RS05970	COG1113	amino acid transport
CFE2614_RS05975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFE2614_RS05980	COG1012	belongs to the aldehyde dehydrogenase family
CFE2614_RS05985	COG0579	oxidoreductase
CFE2614_RS05995	COG1285	pathogenesis
CFE2614_RS06000	COG2211	Major facilitator Superfamily
CFE2614_RS06055	COG3188	usher protein
CFE2614_RS06060	COG3121	Chaperone
CFE2614_RS06105	COG0438	transferase activity, transferring glycosyl groups
CFE2614_RS06110	COG0438	transferase activity, transferring glycosyl groups
CFE2614_RS06110	COG0297	glycogen (starch) synthase activity
CFE2614_RS06145	COG3829	transcription factor binding
CFE2614_RS06150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFE2614_RS06155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFE2614_RS06160	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CFE2614_RS06165	COG2271	Major facilitator Superfamily
CFE2614_RS06170	COG2197	response regulator
CFE2614_RS06175	COG2198	Histidine kinase
CFE2614_RS06175	COG2205	protein histidine kinase activity
CFE2614_RS06175	COG0784	Response regulator, receiver
CFE2614_RS06175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFE2614_RS06195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFE2614_RS06200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFE2614_RS06205	COG3065	identical protein binding
CFE2614_RS06220	COG3962	Belongs to the TPP enzyme family
CFE2614_RS06225	COG0673	inositol 2-dehydrogenase activity
CFE2614_RS06240	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFE2614_RS06250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFE2614_RS06260	COG3718	enzyme involved in inositol metabolism
CFE2614_RS06270	COG1470	cell adhesion involved in biofilm formation
CFE2614_RS06270	COG1388	LysM domain
CFE2614_RS06355	COG0582	viral genome integration into host DNA
CFE2614_RS06365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFE2614_RS06390	COG2867	negative regulation of translational initiation
CFE2614_RS06405	COG0497	DNA recombination
CFE2614_RS06425	COG4536	flavin adenine dinucleotide binding
CFE2614_RS06430	COG4137	Cytochrome C assembly protein
CFE2614_RS06440	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFE2614_RS06465	COG2885	chlorophyll binding
CFE2614_RS06470	COG2199	diguanylate cyclase activity
CFE2614_RS06485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFE2614_RS06490	COG1605	Chorismate mutase
CFE2614_RS06490	COG0287	Prephenate dehydrogenase
CFE2614_RS06495	COG0077	Prephenate dehydratase
CFE2614_RS06495	COG1605	Chorismate mutase
CFE2614_RS06505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFE2614_RS06510	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFE2614_RS06525	COG0542	response to heat
CFE2614_RS06550	COG0477	Major facilitator Superfamily
CFE2614_RS06555	COG5544	Lipoprotein
CFE2614_RS06560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFE2614_RS06570	COG3148	PFAM DTW domain containing protein
CFE2614_RS06575	COG3118	belongs to the thioredoxin family
CFE2614_RS06580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFE2614_RS06605	COG0513	Belongs to the DEAD box helicase family
CFE2614_RS06615	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CFE2614_RS06625	COG1595	DNA-templated transcription, initiation
CFE2614_RS06630	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CFE2614_RS06635	COG3026	antisigma factor binding
CFE2614_RS06640	COG3086	response to oxidative stress
CFE2614_RS06650	COG0681	Belongs to the peptidase S26 family
CFE2614_RS06670	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CFE2614_RS06680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CFE2614_RS06785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFE2614_RS06800	COG1403	HNH endonuclease
CFE2614_RS06825	COG3179	chitinase
CFE2614_RS06865	COG0740	serine-type endopeptidase activity
CFE2614_RS06975	COG1737	Transcriptional regulator
CFE2614_RS06980	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CFE2614_RS06985	COG1263	PTS System
CFE2614_RS06985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFE2614_RS06990	COG0560	Phosphoserine phosphatase
CFE2614_RS07010	COG2205	protein histidine kinase activity
CFE2614_RS07015	COG3170	Tfp pilus assembly protein FimV
CFE2614_RS07020	COG2204	response regulator
CFE2614_RS07025	COG0347	Belongs to the P(II) protein family
CFE2614_RS07030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFE2614_RS07030	COG1017	nitric oxide dioxygenase activity
CFE2614_RS07060	COG4638	Rieske (2fe-2S)
CFE2614_RS07065	COG0583	DNA-binding transcription factor activity
CFE2614_RS07070	COG1940	carbohydrate kinase activity
CFE2614_RS07075	COG0457	Tetratricopeptide repeat
CFE2614_RS07080	COG2814	Major facilitator Superfamily
CFE2614_RS07080	COG0477	Major facilitator Superfamily
CFE2614_RS07090	COG2814	Major facilitator Superfamily
CFE2614_RS07095	COG3711	transcriptional antiterminator
CFE2614_RS07100	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CFE2614_RS07100	COG0517	IMP dehydrogenase activity
CFE2614_RS07105	COG1069	ribulokinase activity
CFE2614_RS07115	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFE2614_RS07120	COG1129	ABC transporter
CFE2614_RS07130	COG3683	transport system, periplasmic component
CFE2614_RS07135	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CFE2614_RS07155	COG1104	cysteine desulfurase activity
CFE2614_RS07160	COG0822	iron-sulfur transferase activity
CFE2614_RS07185	COG0633	Ferredoxin
CFE2614_RS07190	COG2975	iron-sulfur cluster assembly
CFE2614_RS07205	COG2897	thiosulfate sulfurtransferase activity
CFE2614_RS07210	COG2373	Large extracellular alpha-helical protein
CFE2614_RS07215	COG4953	penicillin-binding protein 1C
CFE2614_RS07230	COG1426	Protein conserved in bacteria
CFE2614_RS07245	COG2976	Protein conserved in bacteria
CFE2614_RS07270	COG1645	bacterial-type flagellum-dependent swarming motility
CFE2614_RS07295	COG0517	IMP dehydrogenase activity
CFE2614_RS07295	COG0516	GMP reductase activity
CFE2614_RS07320	COG0668	transmembrane transport
CFE2614_RS07330	COG2200	EAL domain
CFE2614_RS07335	COG0248	Ppx GppA phosphatase
CFE2614_RS07345	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFE2614_RS07355	COG2723	6-phospho-beta-galactosidase activity
CFE2614_RS07365	COG2233	PERMEase
CFE2614_RS07375	COG1393	Belongs to the ArsC family
CFE2614_RS07380	COG4783	chaperone-mediated protein folding
CFE2614_RS07385	COG0628	permease
CFE2614_RS07390	COG3366	ferrous iron transmembrane transporter activity
CFE2614_RS07395	COG0700	Nucleoside recognition
CFE2614_RS07400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFE2614_RS07405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFE2614_RS07410	COG2716	regulation of RNA biosynthetic process
CFE2614_RS07420	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CFE2614_RS07430	COG2321	neutral zinc metallopeptidase
CFE2614_RS07440	COG0400	carboxylic ester hydrolase activity
CFE2614_RS07455	COG1393	Belongs to the ArsC family
CFE2614_RS07465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFE2614_RS07470	COG3850	Histidine kinase
CFE2614_RS07475	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CFE2614_RS07475	COG0493	'glutamate synthase
CFE2614_RS07485	COG5342	invasion associated locus B
CFE2614_RS07490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CFE2614_RS07515	COG4766	ethanolamine catabolic process
CFE2614_RS07520	COG4812	Cobalamin adenosyltransferase
CFE2614_RS07580	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CFE2614_RS07585	COG2207	Transcriptional regulator
CFE2614_RS07595	COG0860	N-Acetylmuramoyl-L-alanine amidase
CFE2614_RS07615	COG2837	iron assimilation
CFE2614_RS07630	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFE2614_RS07635	COG4208	sulfate ABC transporter
CFE2614_RS07640	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFE2614_RS07705	COG3530	Putative quorum-sensing-regulated virulence factor
CFE2614_RS07710	COG0385	Bile acid
CFE2614_RS07715	COG0583	DNA-binding transcription factor activity
CFE2614_RS07725	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CFE2614_RS07730	COG2211	Major facilitator Superfamily
CFE2614_RS07740	COG0583	DNA-binding transcription factor activity
CFE2614_RS07775	COG3415	Transposase
CFE2614_RS07780	COG3415	Transposase
CFE2614_RS07795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CFE2614_RS07810	COG0667	Aldo Keto reductase
CFE2614_RS07815	COG3961	Belongs to the TPP enzyme family
CFE2614_RS07830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS07835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS07840	COG0006	proline dipeptidase activity
CFE2614_RS07845	COG1363	Peptidase, m42
CFE2614_RS07865	COG2207	Transcriptional regulator
CFE2614_RS07870	COG3279	Response regulator of the LytR AlgR family
CFE2614_RS07875	COG3275	phosphorelay sensor kinase activity
CFE2614_RS07880	COG0436	Aminotransferase
CFE2614_RS07895	COG1560	Kdo2-lipid A biosynthetic process
CFE2614_RS07930	COG3122	Protein conserved in bacteria
CFE2614_RS07935	COG0840	transmembrane signaling receptor activity
CFE2614_RS07950	COG2116	formate transmembrane transporter activity
CFE2614_RS07960	COG2067	long-chain fatty acid transport protein
CFE2614_RS07965	COG3691	Protein conserved in bacteria
CFE2614_RS07980	COG2062	phosphohistidine phosphatase, SixA
CFE2614_RS08005	COG0730	response to heat
CFE2614_RS08010	COG3101	peptidyl-lysine hydroxylation
CFE2614_RS08025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFE2614_RS08045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFE2614_RS08055	COG0586	Pfam SNARE associated Golgi protein
CFE2614_RS08065	COG0285	dihydrofolate synthase activity
CFE2614_RS08070	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CFE2614_RS08075	COG1286	toxin biosynthetic process
CFE2614_RS08080	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFE2614_RS08085	COG0163	prenyltransferase activity
CFE2614_RS08095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFE2614_RS08100	COG4215	(ABC) transporter
CFE2614_RS08110	COG4598	ABC transporter
CFE2614_RS08115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFE2614_RS08120	COG1090	epimerase
CFE2614_RS08125	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFE2614_RS08130	COG0625	glutathione transferase activity
CFE2614_RS08135	COG0625	glutathione transferase activity
CFE2614_RS08140	COG0622	Phosphoesterase
CFE2614_RS08150	COG1288	antiporter activity
CFE2614_RS08175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFE2614_RS08180	COG0471	metal ion transport
CFE2614_RS08180	COG0490	domain, Protein
CFE2614_RS08190	COG0436	Aminotransferase
CFE2614_RS08195	COG0583	DNA-binding transcription factor activity
CFE2614_RS08215	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CFE2614_RS08240	COG0839	Belongs to the complex I subunit 6 family
CFE2614_RS08250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFE2614_RS08255	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFE2614_RS08265	COG0835	chemotaxis
CFE2614_RS08265	COG0784	Response regulator, receiver
CFE2614_RS08275	COG2153	protein acetylation
CFE2614_RS08280	COG4575	ribosome binding
CFE2614_RS08285	COG1169	isochorismate synthase
CFE2614_RS08375	COG0247	lactate metabolic process
CFE2614_RS08385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CFE2614_RS08390	COG2271	Major facilitator Superfamily
CFE2614_RS08395	COG0584	glycerophosphoryl diester phosphodiesterase
CFE2614_RS08400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFE2614_RS08435	COG0642	Histidine kinase
CFE2614_RS08435	COG2198	Histidine kinase
CFE2614_RS08440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFE2614_RS08450	COG1477	protein flavinylation
CFE2614_RS08455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFE2614_RS08455	COG2169	Transcriptional regulator
CFE2614_RS08460	COG3145	DNA-N1-methyladenine dioxygenase activity
CFE2614_RS08465	COG4615	Cyclic peptide transporter
CFE2614_RS08470	COG2239	Acts as a magnesium transporter
CFE2614_RS08475	COG0659	secondary active sulfate transmembrane transporter activity
CFE2614_RS08490	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CFE2614_RS08490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CFE2614_RS08495	COG3062	negative regulation of establishment of protein localization
CFE2614_RS08505	COG0437	4 iron, 4 sulfur cluster binding
CFE2614_RS08510	COG0348	domain, Protein
CFE2614_RS08515	COG3043	anaerobic respiration
CFE2614_RS08520	COG3005	denitrification pathway
CFE2614_RS08525	COG4133	protoheme IX ABC transporter activity
CFE2614_RS08535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFE2614_RS08540	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFE2614_RS08550	COG1138	Cytochrome C-type biogenesis protein
CFE2614_RS08555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFE2614_RS08560	COG4235	cytochrome complex assembly
CFE2614_RS08560	COG3088	subunit of a heme lyase
CFE2614_RS08565	COG2197	response regulator
CFE2614_RS08630	COG1061	Type III restriction enzyme res subunit
CFE2614_RS08635	COG1187	pseudouridine synthase activity
CFE2614_RS08640	COG2814	Major facilitator Superfamily
CFE2614_RS08655	COG4172	Belongs to the ABC transporter superfamily
CFE2614_RS08660	COG4239	(ABC) transporter, permease
CFE2614_RS08665	COG4174	ABC transporter (Permease)
CFE2614_RS08670	COG4166	transmembrane transport
CFE2614_RS08675	COG2200	EAL domain
CFE2614_RS08680	COG0791	NLP P60 protein
CFE2614_RS08685	COG0671	phosphoesterase, PA-phosphatase related
CFE2614_RS08690	COG0523	cobalamin synthesis protein
CFE2614_RS08695	COG0246	Mannitol dehydrogenase
CFE2614_RS08700	COG1312	Catalyzes the dehydration of D-mannonate
CFE2614_RS08705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFE2614_RS08710	COG3005	denitrification pathway
CFE2614_RS08720	COG3381	protein complex oligomerization
CFE2614_RS08755	COG4372	Transposase
CFE2614_RS08760	COG3436	PFAM IS66 Orf2 family protein
CFE2614_RS08830	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFE2614_RS08850	COG1105	Belongs to the carbohydrate kinase PfkB family
CFE2614_RS08855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS08855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS08855	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CFE2614_RS08860	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CFE2614_RS08870	COG0583	DNA-binding transcription factor activity
CFE2614_RS08875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFE2614_RS08880	COG2313	pseudouridylate synthase activity
CFE2614_RS08885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CFE2614_RS08890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFE2614_RS08890	COG1522	sequence-specific DNA binding
CFE2614_RS08900	COG2855	membrane
CFE2614_RS08905	COG0583	DNA-binding transcription factor activity
CFE2614_RS08910	COG0833	amino acid
CFE2614_RS08915	COG4771	TonB-dependent receptor
CFE2614_RS08920	COG2271	Major facilitator Superfamily
CFE2614_RS08925	COG0560	Phosphoserine phosphatase
CFE2614_RS08930	COG1760	l-serine dehydratase
CFE2614_RS08950	COG2311	Membrane
CFE2614_RS08965	COG1129	ABC transporter
CFE2614_RS08980	COG0493	'glutamate synthase
CFE2614_RS08990	COG2949	membrane
CFE2614_RS09000	COG1346	cytolysis
CFE2614_RS09015	COG2271	Major facilitator Superfamily
CFE2614_RS09030	COG0625	glutathione transferase activity
CFE2614_RS09035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFE2614_RS09040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFE2614_RS09060	COG0586	Pfam SNARE associated Golgi protein
CFE2614_RS09070	COG1686	Belongs to the peptidase S11 family
CFE2614_RS09075	COG0277	FAD linked oxidase domain protein
CFE2614_RS09080	COG1472	Belongs to the glycosyl hydrolase 3 family
CFE2614_RS09085	COG1732	Glycine betaine
CFE2614_RS09090	COG1174	glycine betaine transport
CFE2614_RS09095	COG1125	glycine betaine transport
CFE2614_RS09100	COG1174	glycine betaine transport
CFE2614_RS09110	COG0789	Transcriptional regulator
CFE2614_RS09115	COG3275	phosphorelay sensor kinase activity
CFE2614_RS09125	COG4807	Protein conserved in bacteria
CFE2614_RS09130	COG4808	Protein conserved in bacteria
CFE2614_RS09140	COG0489	protein tyrosine kinase activity
CFE2614_RS09155	COG3121	Chaperone
CFE2614_RS09160	COG3188	usher protein
CFE2614_RS09170	COG5455	response to cobalt ion
CFE2614_RS09195	COG0582	viral genome integration into host DNA
CFE2614_RS09275	COG0351	phosphomethylpyrimidine kinase
CFE2614_RS09280	COG2188	Transcriptional regulator
CFE2614_RS09285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFE2614_RS09290	COG1397	ADP-ribosylglycohydrolase
CFE2614_RS09295	COG2211	Major facilitator Superfamily
CFE2614_RS09305	COG1830	Aldolase
CFE2614_RS09315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFE2614_RS09320	COG4160	amino acid transport
CFE2614_RS09325	COG4215	(ABC) transporter
CFE2614_RS09330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFE2614_RS09335	COG1126	abc transporter atp-binding protein
CFE2614_RS09350	COG3023	N-Acetylmuramoyl-L-alanine amidase
CFE2614_RS09355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFE2614_RS09360	COG0702	epimerase
CFE2614_RS09365	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CFE2614_RS09370	COG0028	Belongs to the TPP enzyme family
CFE2614_RS09380	COG4529	Protein conserved in bacteria
CFE2614_RS09385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFE2614_RS09395	COG2431	L-lysine efflux transmembrane transporter activity
CFE2614_RS09405	COG3593	DNA synthesis involved in DNA repair
CFE2614_RS09410	COG2990	Protein conserved in bacteria
CFE2614_RS09415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFE2614_RS09425	COG1278	Cold shock
CFE2614_RS09435	COG0542	response to heat
CFE2614_RS09440	COG0826	peptidase U32
CFE2614_RS09450	COG0745	RESPONSE REGULATOR receiver
CFE2614_RS09455	COG2205	protein histidine kinase activity
CFE2614_RS09485	COG0443	Heat shock 70 kDa protein
CFE2614_RS09490	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CFE2614_RS09495	COG5002	protein histidine kinase activity
CFE2614_RS09495	COG5001	Diguanylate cyclase
CFE2614_RS09495	COG3447	MASE1 domain protein
CFE2614_RS09510	COG2982	Protein involved in outer membrane biogenesis
CFE2614_RS09515	COG1253	flavin adenine dinucleotide binding
CFE2614_RS09535	COG0463	Glycosyl transferase, family 2
CFE2614_RS09540	COG1045	serine acetyltransferase
CFE2614_RS09545	COG0438	transferase activity, transferring glycosyl groups
CFE2614_RS09555	COG1216	Glycosyl transferase, family 2
CFE2614_RS09560	COG0110	maltose O-acetyltransferase activity
CFE2614_RS09565	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CFE2614_RS09570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFE2614_RS09575	COG1051	belongs to the nudix hydrolase family
CFE2614_RS09580	COG0297	glycogen (starch) synthase activity
CFE2614_RS09590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFE2614_RS09595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFE2614_RS09600	COG2244	polysaccharide biosynthetic process
CFE2614_RS09605	COG2327	Polysaccharide pyruvyl transferase
CFE2614_RS09635	COG1215	transferase activity, transferring glycosyl groups
CFE2614_RS09640	COG0438	transferase activity, transferring glycosyl groups
CFE2614_RS09675	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFE2614_RS09695	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CFE2614_RS09700	COG0140	phosphoribosyl-ATP diphosphatase activity
CFE2614_RS09700	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFE2614_RS09715	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFE2614_RS09745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFE2614_RS09750	COG0583	DNA-binding transcription factor activity
CFE2614_RS09760	COG0531	amino acid
CFE2614_RS09765	COG2925	Exonuclease
CFE2614_RS09800	COG1289	transmembrane transporter activity
CFE2614_RS09835	COG4656	Part of a membrane complex involved in electron transport
CFE2614_RS09845	COG1012	belongs to the aldehyde dehydrogenase family
CFE2614_RS09855	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CFE2614_RS10025	COG1376	ErfK ybiS ycfS ynhG family protein
CFE2614_RS10030	COG3842	ATPase activity
CFE2614_RS10035	COG1178	ABC-type Fe3 transport system permease component
CFE2614_RS10040	COG1840	ABC-type Fe3 transport system, periplasmic component
CFE2614_RS10065	COG2076	Multidrug Resistance protein
CFE2614_RS10070	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFE2614_RS10075	COG1418	mRNA catabolic process
CFE2614_RS10080	COG0270	DNA (cytosine-5-)-methyltransferase activity
CFE2614_RS10085	COG3727	T/G mismatch-specific endonuclease activity
CFE2614_RS10090	COG0697	spore germination
CFE2614_RS10095	COG2354	Protein conserved in bacteria
CFE2614_RS10100	COG5475	Uncharacterized small protein (DUF2158)
CFE2614_RS10160	COG2882	bacterial-type flagellum organization
CFE2614_RS10165	COG1157	protein secretion by the type III secretion system
CFE2614_RS10190	COG0425	Belongs to the sulfur carrier protein TusA family
CFE2614_RS10205	COG0366	Alpha amylase catalytic
CFE2614_RS10240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFE2614_RS10250	COG0765	amino acid transport
CFE2614_RS10255	COG1126	abc transporter atp-binding protein
CFE2614_RS10260	COG2197	response regulator
CFE2614_RS10270	COG2197	response regulator
CFE2614_RS10315	COG1305	Transglutaminase-like
CFE2614_RS10325	COG2608	mercury ion transmembrane transporter activity
CFE2614_RS10330	COG3318	Belongs to the UPF0149 family
CFE2614_RS10330	COG3012	SEC-C Motif Domain Protein
CFE2614_RS10335	COG0814	amino acid
CFE2614_RS10345	COG1528	Iron-storage protein
CFE2614_RS10360	COG0477	Major facilitator Superfamily
CFE2614_RS10370	COG1528	Iron-storage protein
CFE2614_RS10380	COG1879	ABC-type sugar transport system periplasmic component
CFE2614_RS10385	COG1129	ABC transporter
CFE2614_RS10390	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFE2614_RS10405	COG0589	response to stress
CFE2614_RS10440	COG0835	chemotaxis
CFE2614_RS10450	COG1301	dicarboxylic acid transport
CFE2614_RS10460	COG0840	transmembrane signaling receptor activity
CFE2614_RS10475	COG0745	RESPONSE REGULATOR receiver
CFE2614_RS10500	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CFE2614_RS10515	COG3102	Protein conserved in bacteria
CFE2614_RS10535	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CFE2614_RS10540	COG1801	Protein of unknown function DUF72
CFE2614_RS10545	COG0582	viral genome integration into host DNA
CFE2614_RS10630	COG4626	Terminase
CFE2614_RS10630	COG1802	Transcriptional regulator
CFE2614_RS10635	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CFE2614_RS10645	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFE2614_RS10660	COG1403	HNH endonuclease
CFE2614_RS10685	COG3179	chitinase
CFE2614_RS10710	COG3646	Phage regulatory protein
CFE2614_RS10730	COG3436	PFAM IS66 Orf2 family protein
CFE2614_RS10735	COG4372	Transposase
CFE2614_RS10760	COG0740	serine-type endopeptidase activity
CFE2614_RS10865	COG2135	peptidase activity
CFE2614_RS10875	COG1335	isochorismatase
CFE2614_RS10885	COG0494	nUDIX hydrolase
CFE2614_RS10910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFE2614_RS10920	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CFE2614_RS10925	COG0739	heme binding
CFE2614_RS10930	COG1560	Kdo2-lipid A biosynthetic process
CFE2614_RS10940	COG1737	Transcriptional regulator
CFE2614_RS10950	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFE2614_RS10955	COG0129	dihydroxy-acid dehydratase activity
CFE2614_RS10960	COG0800	Aldolase
CFE2614_RS10970	COG3141	response to X-ray
CFE2614_RS10980	COG2979	Protein of unknown function (DUF533)
CFE2614_RS10985	COG1770	oligopeptidase
CFE2614_RS10990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFE2614_RS10995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFE2614_RS11005	COG2372	response to copper ion
CFE2614_RS11010	COG1276	copper resistance
CFE2614_RS11020	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CFE2614_RS11040	COG3008	intermembrane lipid transfer
CFE2614_RS11045	COG2995	paraquat-inducible protein a
CFE2614_RS11050	COG1956	GAF domain-containing protein
CFE2614_RS11170	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFE2614_RS11200	COG2197	response regulator
CFE2614_RS11215	COG2814	Major facilitator Superfamily
CFE2614_RS11220	COG1414	Transcriptional regulator
CFE2614_RS11250	COG0768	penicillin binding
CFE2614_RS11255	COG2226	methyltransferase
CFE2614_RS11270	COG3716	PTS system mannose fructose sorbose family IID component
CFE2614_RS11275	COG3715	PTS system
CFE2614_RS11280	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFE2614_RS11280	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFE2614_RS11285	COG1253	flavin adenine dinucleotide binding
CFE2614_RS11290	COG2200	EAL domain
CFE2614_RS11295	COG1760	l-serine dehydratase
CFE2614_RS11315	COG0251	oxidation-reduction process
CFE2614_RS11320	COG1199	ATP-dependent helicase activity
CFE2614_RS11325	COG1214	PFAM Peptidase M22, glycoprotease
CFE2614_RS11330	COG3065	identical protein binding
CFE2614_RS11335	COG0318	PFAM AMP-dependent synthetase and ligase
CFE2614_RS11340	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFE2614_RS11345	COG0473	3-isopropylmalate dehydrogenase activity
CFE2614_RS11350	COG0583	DNA-binding transcription factor activity
CFE2614_RS11360	COG2894	cell division
CFE2614_RS11375	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFE2614_RS11405	COG2719	SpoVR family
CFE2614_RS11415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFE2614_RS11425	COG1619	proteins homologs of microcin C7 resistance protein MccF
CFE2614_RS11450	COG0157	Belongs to the NadC ModD family
CFE2614_RS11460	COG1120	ATPase activity
CFE2614_RS11465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFE2614_RS11470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CFE2614_RS11485	COG1461	Dihydroxyacetone kinase
CFE2614_RS11490	COG2376	Dihydroxyacetone kinase
CFE2614_RS11495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CFE2614_RS11540	COG0012	GTP binding
CFE2614_RS11555	COG0527	aspartate kinase activity
CFE2614_RS11560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFE2614_RS11565	COG0076	glutamate decarboxylase activity
CFE2614_RS11570	COG0659	secondary active sulfate transmembrane transporter activity
CFE2614_RS11600	COG2890	protein-(glutamine-N5) methyltransferase activity
CFE2614_RS11605	COG3094	Invasion gene expression up-regulator, SirB
CFE2614_RS11620	COG0387	Pfam Sodium calcium exchanger
CFE2614_RS11625	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CFE2614_RS11635	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CFE2614_RS11640	COG4932	domain protein
CFE2614_RS11645	COG2197	response regulator
CFE2614_RS11650	COG3850	Histidine kinase
CFE2614_RS11660	COG2223	nitrite transmembrane transporter activity
CFE2614_RS11665	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CFE2614_RS11670	COG1140	nitrate reductase beta subunit
CFE2614_RS11675	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CFE2614_RS11680	COG2181	nitrate reductase activity
CFE2614_RS11710	COG0788	formyltetrahydrofolate deformylase activity
CFE2614_RS11720	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFE2614_RS11725	COG0745	RESPONSE REGULATOR receiver
CFE2614_RS11730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFE2614_RS11740	COG1435	thymidine kinase activity
CFE2614_RS11745	COG1454	alcohol dehydrogenase
CFE2614_RS11745	COG1012	belongs to the aldehyde dehydrogenase family
CFE2614_RS11750	COG2095	MarC family integral membrane protein
CFE2614_RS11780	COG0444	Belongs to the ABC transporter superfamily
CFE2614_RS11790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFE2614_RS11810	COG2350	Protein conserved in bacteria
CFE2614_RS11835	COG3047	cAMP biosynthetic process
CFE2614_RS11840	COG0217	transcriptional regulatory protein
CFE2614_RS11855	COG3706	GGDEF domain
CFE2614_RS11895	COG0009	L-threonylcarbamoyladenylate synthase
CFE2614_RS11900	COG1187	pseudouridine synthase activity
CFE2614_RS11910	COG1028	Short-chain dehydrogenase reductase Sdr
CFE2614_RS11915	COG0616	signal peptide processing
CFE2614_RS11930	COG0583	DNA-binding transcription factor activity
CFE2614_RS11940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFE2614_RS11950	COG0671	phosphoesterase, PA-phosphatase related
CFE2614_RS11955	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CFE2614_RS11960	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CFE2614_RS11970	COG0023	Translation Initiation Factor
CFE2614_RS11980	COG1349	DNA-binding transcription factor activity
CFE2614_RS11995	COG5001	Diguanylate cyclase
CFE2614_RS12005	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFE2614_RS12005	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFE2614_RS12010	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFE2614_RS12030	COG4171	peptide transport system, permease
CFE2614_RS12055	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CFE2614_RS12060	COG1842	Phage shock protein A
CFE2614_RS12070	COG1983	PspC domain protein
CFE2614_RS12080	COG0366	Alpha amylase catalytic
CFE2614_RS12085	COG1653	transport
CFE2614_RS12090	COG1175	transmembrane transport
CFE2614_RS12095	COG0395	ABC-type sugar transport system, permease component
CFE2614_RS12100	COG1063	alcohol dehydrogenase
CFE2614_RS12105	COG1082	Xylose isomerase domain protein TIM barrel
CFE2614_RS12110	COG0673	inositol 2-dehydrogenase activity
CFE2614_RS12115	COG1554	hydrolase, family 65, central catalytic
CFE2614_RS12120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFE2614_RS12125	COG3842	ATPase activity
CFE2614_RS12135	COG1609	Transcriptional regulator
CFE2614_RS12140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFE2614_RS12145	COG3106	COG3106 Predicted ATPase
CFE2614_RS12160	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CFE2614_RS12165	COG4948	Mandelate Racemase Muconate Lactonizing
CFE2614_RS12170	COG2866	Carboxypeptidase
CFE2614_RS12175	COG4166	transmembrane transport
CFE2614_RS12195	COG1349	DNA-binding transcription factor activity
CFE2614_RS12200	COG0346	lactoylglutathione lyase activity
CFE2614_RS12215	COG1064	alcohol dehydrogenase
CFE2614_RS12220	COG0668	transmembrane transport
CFE2614_RS12225	COG3182	Iron-regulated membrane protein
CFE2614_RS12245	COG2840	Smr protein MutS2
CFE2614_RS12250	COG3706	GGDEF domain
CFE2614_RS12260	COG0840	transmembrane signaling receptor activity
CFE2614_RS12275	COG0513	Belongs to the DEAD box helicase family
CFE2614_RS12285	COG0589	response to stress
CFE2614_RS12295	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFE2614_RS12300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFE2614_RS12300	COG1013	pyruvate-flavodoxin oxidoreductase activity
CFE2614_RS12300	COG0674	pyruvate-flavodoxin oxidoreductase activity
CFE2614_RS12300	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CFE2614_RS12305	COG3042	response to heat
CFE2614_RS12310	COG3187	Heat shock protein
CFE2614_RS12315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFE2614_RS12325	COG2911	Protein conserved in bacteria
CFE2614_RS12335	COG3784	Protein of unknown function (DUF1318)
CFE2614_RS12350	COG1643	Atp-dependent helicase
CFE2614_RS12355	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CFE2614_RS12360	COG1012	belongs to the aldehyde dehydrogenase family
CFE2614_RS12365	COG0657	acetylesterase activity
CFE2614_RS12365	COG2755	lipolytic protein G-D-S-L family
CFE2614_RS12370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CFE2614_RS12375	COG3038	cytochrome b561
CFE2614_RS12385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFE2614_RS12390	COG2864	formate dehydrogenase
CFE2614_RS12395	COG0437	4 iron, 4 sulfur cluster binding
CFE2614_RS12400	COG0243	molybdopterin cofactor binding
CFE2614_RS12400	COG3383	formate dehydrogenase (NAD+) activity
CFE2614_RS12410	COG3059	membrane
CFE2614_RS12435	COG0840	transmembrane signaling receptor activity
CFE2614_RS12460	COG3121	Chaperone
CFE2614_RS12470	COG0583	DNA-binding transcription factor activity
CFE2614_RS12475	COG1227	inorganic diphosphatase activity
CFE2614_RS12480	COG5383	Protein conserved in bacteria
CFE2614_RS12490	COG2841	Protein conserved in bacteria
CFE2614_RS12500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFE2614_RS12505	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CFE2614_RS12510	COG1275	C4-dicarboxylate transporter malic acid transport protein
CFE2614_RS12515	COG0500	methyltransferase
CFE2614_RS12535	COG3135	benzoate transporter
CFE2614_RS12540	COG1396	sequence-specific DNA binding
CFE2614_RS12545	COG0826	peptidase U32
CFE2614_RS12560	COG1294	oxidase, subunit
CFE2614_RS12565	COG1271	oxidase subunit
CFE2614_RS12575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFE2614_RS12580	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CFE2614_RS12585	COG3842	ATPase activity
CFE2614_RS12590	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFE2614_RS12595	COG1177	transmembrane transport
CFE2614_RS12645	COG0747	negative chemotaxis
CFE2614_RS12655	COG3238	Protein conserved in bacteria
CFE2614_RS12660	COG1247	-acetyltransferase
CFE2614_RS12670	COG2130	NADP-dependent
CFE2614_RS12690	COG0840	transmembrane signaling receptor activity
CFE2614_RS12695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFE2614_RS12700	COG1473	amidohydrolase
CFE2614_RS12705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFE2614_RS12710	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CFE2614_RS12725	COG1126	abc transporter atp-binding protein
CFE2614_RS12730	COG3321	synthase
CFE2614_RS12730	COG1028	Short-chain dehydrogenase reductase Sdr
CFE2614_RS12730	COG0604	alcohol dehydrogenase
CFE2614_RS12735	COG0583	DNA-binding transcription factor activity
CFE2614_RS12740	COG0625	glutathione transferase activity
CFE2614_RS12765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFE2614_RS12770	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CFE2614_RS12785	COG0384	phenazine biosynthesis protein PhzF
CFE2614_RS12790	COG2181	nitrate reductase activity
CFE2614_RS12795	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CFE2614_RS12800	COG1140	nitrate reductase beta subunit
CFE2614_RS12805	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CFE2614_RS12810	COG2223	nitrite transmembrane transporter activity
CFE2614_RS12835	COG0697	spore germination
CFE2614_RS12840	COG0243	molybdopterin cofactor binding
CFE2614_RS12840	COG3383	formate dehydrogenase (NAD+) activity
CFE2614_RS12845	COG3383	formate dehydrogenase (NAD+) activity
CFE2614_RS12845	COG0243	molybdopterin cofactor binding
CFE2614_RS12850	COG0437	4 iron, 4 sulfur cluster binding
CFE2614_RS12855	COG2864	formate dehydrogenase
CFE2614_RS12860	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CFE2614_RS12865	COG0488	(ABC) transporter
CFE2614_RS12880	COG1764	response to oxidative stress
CFE2614_RS12885	COG1028	Short-chain dehydrogenase reductase Sdr
CFE2614_RS12890	COG2610	gluconate transmembrane transporter activity
CFE2614_RS12895	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFE2614_RS12905	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFE2614_RS12910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CFE2614_RS12920	COG4608	Belongs to the ABC transporter superfamily
CFE2614_RS12925	COG0444	Belongs to the ABC transporter superfamily
CFE2614_RS12930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFE2614_RS12935	COG0601	transmembrane transport
CFE2614_RS12940	COG0747	negative chemotaxis
CFE2614_RS12945	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CFE2614_RS12960	COG0840	transmembrane signaling receptor activity
CFE2614_RS12980	COG1649	PFAM Uncharacterised BCR, COG1649
CFE2614_RS12985	COG4628	conserved protein (DUF2132)
CFE2614_RS13010	COG3121	Chaperone
CFE2614_RS13025	COG3121	Chaperone
CFE2614_RS13055	COG3781	membrane
CFE2614_RS13085	COG1012	belongs to the aldehyde dehydrogenase family
CFE2614_RS13090	COG0583	DNA-binding transcription factor activity
CFE2614_RS13105	COG1846	Transcriptional regulator
CFE2614_RS13120	COG0697	spore germination
CFE2614_RS13125	COG2814	Major facilitator Superfamily
CFE2614_RS13130	COG0410	ABC transporter
CFE2614_RS13135	COG1129	ABC transporter
CFE2614_RS13165	COG3706	GGDEF domain
CFE2614_RS13180	COG4221	oxidoreductase activity
CFE2614_RS13185	COG1802	Transcriptional regulator
CFE2614_RS13195	COG0246	Mannitol dehydrogenase
CFE2614_RS13205	COG4948	Mandelate Racemase Muconate Lactonizing
CFE2614_RS13220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFE2614_RS13235	COG0243	molybdopterin cofactor binding
CFE2614_RS13240	COG0437	4 iron, 4 sulfur cluster binding
CFE2614_RS13245	COG3302	dmso reductase anchor subunit
CFE2614_RS13250	COG3381	protein complex oligomerization
CFE2614_RS13260	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CFE2614_RS13265	COG1940	carbohydrate kinase activity
CFE2614_RS13270	COG0583	DNA-binding transcription factor activity
CFE2614_RS13275	COG2814	Major facilitator Superfamily
CFE2614_RS13285	COG2205	protein histidine kinase activity
CFE2614_RS13290	COG0745	RESPONSE REGULATOR receiver
CFE2614_RS13305	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CFE2614_RS13315	COG3591	Belongs to the peptidase S1B family
CFE2614_RS13335	COG0628	permease
CFE2614_RS13340	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CFE2614_RS13345	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CFE2614_RS13355	COG0531	amino acid
CFE2614_RS13365	COG3136	membrane protein required for alginate biosynthesis
CFE2614_RS13370	COG0745	RESPONSE REGULATOR receiver
CFE2614_RS13375	COG1823	symporter activity
CFE2614_RS13380	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CFE2614_RS13390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFE2614_RS13405	COG2205	protein histidine kinase activity
CFE2614_RS13420	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CFE2614_RS13420	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CFE2614_RS13430	COG5339	Protein conserved in bacteria
CFE2614_RS13435	COG1609	Transcriptional regulator
CFE2614_RS13440	COG1263	PTS System
CFE2614_RS13440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFE2614_RS13445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CFE2614_RS13455	COG0673	inositol 2-dehydrogenase activity
CFE2614_RS13505	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFE2614_RS13520	COG0625	glutathione transferase activity
CFE2614_RS13525	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CFE2614_RS13540	COG3895	Periplasmic Protein
CFE2614_RS13565	COG1566	PFAM secretion protein HlyD family protein
CFE2614_RS13575	COG2032	superoxide dismutase activity
CFE2614_RS13580	COG4989	oxidoreductase activity
CFE2614_RS13585	COG3313	Fe-S protein
CFE2614_RS13590	COG1309	transcriptional regulator
CFE2614_RS13595	COG1902	pentaerythritol trinitrate reductase activity
CFE2614_RS13600	COG0346	lactoylglutathione lyase activity
CFE2614_RS13610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CFE2614_RS13615	COG0791	NLP P60 protein
CFE2614_RS13620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFE2614_RS13625	COG2814	Major facilitator Superfamily
CFE2614_RS13640	COG0583	DNA-binding transcription factor activity
CFE2614_RS13645	COG2814	Major facilitator Superfamily
CFE2614_RS13650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFE2614_RS13655	COG0307	riboflavin synthase, alpha
CFE2614_RS13680	COG0251	oxidation-reduction process
CFE2614_RS13700	COG3300	MHYT domain
CFE2614_RS13700	COG5001	Diguanylate cyclase
CFE2614_RS13705	COG0386	Belongs to the glutathione peroxidase family
CFE2614_RS13710	COG0628	permease
CFE2614_RS13725	COG1028	Short-chain dehydrogenase reductase Sdr
CFE2614_RS13730	COG2378	regulation of single-species biofilm formation
CFE2614_RS13750	COG3121	Chaperone
CFE2614_RS13755	COG3188	usher protein
CFE2614_RS13770	COG4977	sequence-specific DNA binding
CFE2614_RS13805	COG1120	ATPase activity
CFE2614_RS13810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFE2614_RS13815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CFE2614_RS13820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFE2614_RS13835	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CFE2614_RS13845	COG1012	belongs to the aldehyde dehydrogenase family
CFE2614_RS13860	COG1113	amino acid transport
CFE2614_RS13870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFE2614_RS13885	COG0765	amino acid transport
CFE2614_RS13895	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CFE2614_RS13900	COG0437	4 iron, 4 sulfur cluster binding
CFE2614_RS13910	COG2414	aldehyde ferredoxin oxidoreductase
CFE2614_RS13915	COG0437	4 iron, 4 sulfur cluster binding
CFE2614_RS13965	COG1464	Belongs to the NlpA lipoprotein family
CFE2614_RS13970	COG2011	ABC-type metal ion transport system permease component
CFE2614_RS13980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFE2614_RS13990	COG2267	carboxylic ester hydrolase activity
CFE2614_RS13995	COG0531	amino acid
CFE2614_RS14010	COG1376	ErfK ybiS ycfS ynhG family protein
CFE2614_RS14025	COG0719	Fe-S assembly protein
CFE2614_RS14030	COG0396	ATPase activity
CFE2614_RS14035	COG0719	Fe-S assembly protein
CFE2614_RS14040	COG0316	Belongs to the HesB IscA family
CFE2614_RS14045	COG0583	DNA-binding transcription factor activity
CFE2614_RS14060	COG2050	protein possibly involved in aromatic compounds catabolism
CFE2614_RS14065	COG0277	FAD linked oxidase domain protein
CFE2614_RS14065	COG0247	lactate metabolic process
CFE2614_RS14075	COG0628	permease
CFE2614_RS14090	COG0738	Major facilitator superfamily
CFE2614_RS14095	COG2271	Major facilitator Superfamily
CFE2614_RS14110	COG4670	ketone body catabolic process
CFE2614_RS14115	COG1960	acyl-CoA dehydrogenase activity
CFE2614_RS14120	COG1917	Cupin 2, conserved barrel domain protein
CFE2614_RS14120	COG2207	Transcriptional regulator
CFE2614_RS14125	COG2086	electron transfer activity
CFE2614_RS14130	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CFE2614_RS14135	COG0644	oxidoreductase
CFE2614_RS14140	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CFE2614_RS14145	COG0318	PFAM AMP-dependent synthetase and ligase
CFE2614_RS14150	COG0574	Belongs to the PEP-utilizing enzyme family
CFE2614_RS14150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFE2614_RS14160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFE2614_RS14165	COG4256	Hemin uptake protein
CFE2614_RS14170	COG4771	TonB-dependent receptor
CFE2614_RS14175	COG3720	iron ion transport
CFE2614_RS14180	COG4558	Periplasmic binding protein
CFE2614_RS14185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFE2614_RS14205	COG0791	NLP P60 protein
CFE2614_RS14215	COG0386	Belongs to the glutathione peroxidase family
CFE2614_RS14250	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CFE2614_RS14270	COG3137	Salt-induced outer membrane protein
CFE2614_RS14275	COG1105	Belongs to the carbohydrate kinase PfkB family
CFE2614_RS14280	COG3001	Fructosamine kinase
CFE2614_RS14290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFE2614_RS14295	COG1028	Short-chain dehydrogenase reductase Sdr
CFE2614_RS14300	COG1988	membrane-bound metal-dependent
CFE2614_RS14305	COG1823	symporter activity
CFE2614_RS14315	COG0753	catalase activity
CFE2614_RS14325	COG1486	melibiose metabolic process
CFE2614_RS14330	COG1917	Cupin 2, conserved barrel domain protein
CFE2614_RS14330	COG2169	Transcriptional regulator
CFE2614_RS14335	COG1447	Phosphotransferase system cellobiose-specific component IIA
CFE2614_RS14340	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFE2614_RS14345	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFE2614_RS14355	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFE2614_RS14365	COG0322	excinuclease ABC activity
CFE2614_RS14375	COG3678	ATP-independent chaperone mediated protein folding
CFE2614_RS14410	COG0708	Exodeoxyribonuclease III
CFE2614_RS14415	COG0398	Pfam SNARE associated Golgi protein
CFE2614_RS14420	COG0398	Pfam SNARE associated Golgi protein
CFE2614_RS14425	COG4134	Bacterial extracellular solute-binding protein
CFE2614_RS14430	COG4135	transport system, permease component
CFE2614_RS14435	COG4136	ATPase activity
CFE2614_RS14440	COG2897	thiosulfate sulfurtransferase activity
CFE2614_RS14445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFE2614_RS14450	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFE2614_RS14455	COG0494	nUDIX hydrolase
CFE2614_RS14470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFE2614_RS14480	COG0778	Nitroreductase
CFE2614_RS14485	COG0616	signal peptide processing
CFE2614_RS14490	COG0252	asparaginase activity
CFE2614_RS14495	COG1335	isochorismatase
CFE2614_RS14500	COG2814	Major facilitator Superfamily
CFE2614_RS14505	COG1349	DNA-binding transcription factor activity
CFE2614_RS14510	COG0667	Aldo Keto reductase
CFE2614_RS14515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFE2614_RS14520	COG0191	fructose-bisphosphate aldolase activity
CFE2614_RS14525	COG1063	alcohol dehydrogenase
CFE2614_RS14530	COG2271	Major facilitator Superfamily
CFE2614_RS14535	COG1063	alcohol dehydrogenase
CFE2614_RS14550	COG3139	Protein of unknown function (DUF1315)
CFE2614_RS14570	COG0656	L-ascorbic acid biosynthetic process
CFE2614_RS14575	COG3713	MltA-interacting MipA family protein
CFE2614_RS14580	COG2766	serine protein kinase
CFE2614_RS14590	COG2226	methyltransferase
CFE2614_RS14595	COG2199	diguanylate cyclase activity
CFE2614_RS14600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFE2614_RS14610	COG2207	Transcriptional regulator
CFE2614_RS14615	COG2807	transmembrane transport
CFE2614_RS14620	COG0504	CTP synthase activity
CFE2614_RS14625	COG3189	MarR family transcriptional regulator
CFE2614_RS14630	COG3042	response to heat
CFE2614_RS14635	COG2203	Gaf domain
CFE2614_RS14635	COG2199	diguanylate cyclase activity
CFE2614_RS14650	COG2261	transglycosylase associated protein
CFE2614_RS14655	COG3383	formate dehydrogenase (NAD+) activity
CFE2614_RS14670	COG3615	Tellurite resistance protein tehB
CFE2614_RS14680	COG3443	Belongs to the bacterial solute-binding protein 9 family
CFE2614_RS14685	COG1124	(ABC) transporter
CFE2614_RS14695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFE2614_RS14700	COG0601	transmembrane transport
CFE2614_RS14705	COG0747	negative chemotaxis
CFE2614_RS14710	COG4771	TonB-dependent receptor
CFE2614_RS14725	COG2200	EAL domain
CFE2614_RS14775	COG0431	NADPH-dependent FMN reductase
CFE2614_RS14780	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFE2614_RS14795	COG0538	isocitrate dehydrogenase activity
CFE2614_RS14825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFE2614_RS14830	COG2135	peptidase activity
CFE2614_RS14845	COG4372	Transposase
CFE2614_RS14850	COG3436	PFAM IS66 Orf2 family protein
CFE2614_RS14865	COG3272	Protein of unknown function (DUF1722)
CFE2614_RS14885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFE2614_RS14900	COG0300	oxidoreductase activity
CFE2614_RS14910	COG0789	Transcriptional regulator
CFE2614_RS15000	COG0616	signal peptide processing
CFE2614_RS15015	COG1802	Transcriptional regulator
CFE2614_RS15015	COG4626	Terminase
CFE2614_RS15030	COG3038	cytochrome b561
CFE2614_RS15075	COG3772	lysozyme
CFE2614_RS15110	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CFE2614_RS15145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CFE2614_RS15200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFE2614_RS15210	COG0582	viral genome integration into host DNA
CFE2614_RS15225	COG2850	peptidyl-arginine hydroxylation
CFE2614_RS15245	COG1177	transmembrane transport
CFE2614_RS15255	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CFE2614_RS15265	COG4591	ABC-type transport system involved in lipoprotein release permease component
CFE2614_RS15270	COG1136	(ABC) transporter
CFE2614_RS15275	COG4591	ABC-type transport system involved in lipoprotein release permease component
CFE2614_RS15280	COG4763	Acyl-transferase
CFE2614_RS15285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFE2614_RS15290	COG1376	ErfK ybiS ycfS ynhG family protein
CFE2614_RS15290	COG1388	LysM domain
CFE2614_RS15300	COG1309	transcriptional regulator
CFE2614_RS15310	COG3134	Outer membrane lipoprotein
CFE2614_RS15315	COG1252	NADH dehydrogenase
CFE2614_RS15340	COG5633	Lipoprotein
CFE2614_RS15345	COG0537	adenosine 5'-monophosphoramidase activity
CFE2614_RS15350	COG0583	DNA-binding transcription factor activity
CFE2614_RS15360	COG0309	Hydrogenase expression formation protein (HypE)
CFE2614_RS15365	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CFE2614_RS15370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFE2614_RS15375	COG2223	nitrite transmembrane transporter activity
CFE2614_RS15385	COG0534	Mate efflux family protein
CFE2614_RS15395	COG0583	DNA-binding transcription factor activity
CFE2614_RS15415	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CFE2614_RS15420	COG1027	Aspartate ammonia-lyase
CFE2614_RS15425	COG0583	DNA-binding transcription factor activity
CFE2614_RS15445	COG1595	DNA-templated transcription, initiation
CFE2614_RS15450	COG3712	iron ion homeostasis
CFE2614_RS15455	COG4772	TonB-dependent receptor
CFE2614_RS15460	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CFE2614_RS15465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFE2614_RS15470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFE2614_RS15475	COG1120	ATPase activity
CFE2614_RS15500	COG0477	Major facilitator Superfamily
CFE2614_RS15505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFE2614_RS15520	COG0084	hydrolase, TatD family'
CFE2614_RS15525	COG0470	DNA polymerase III
CFE2614_RS15535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFE2614_RS15540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFE2614_RS15545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFE2614_RS15580	COG1399	metal-binding, possibly nucleic acid-binding protein
CFE2614_RS15590	COG0564	pseudouridine synthase activity
CFE2614_RS15605	COG1530	ribonuclease E activity
CFE2614_RS15610	COG0583	DNA-binding transcription factor activity
CFE2614_RS15615	COG2814	Major facilitator Superfamily
CFE2614_RS15645	COG4786	Flagellar basal body rod
CFE2614_RS15650	COG4787	bacterial-type flagellum-dependent cell motility
CFE2614_RS15665	COG1558	bacterial-type flagellum-dependent cell motility
CFE2614_RS15705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFE2614_RS15745	COG3038	cytochrome b561
CFE2614_RS15760	COG1560	Kdo2-lipid A biosynthetic process
CFE2614_RS15770	COG2199	diguanylate cyclase activity
CFE2614_RS15780	COG5645	(Lipo)protein
CFE2614_RS15870	COG3381	protein complex oligomerization
CFE2614_RS15910	COG2962	Rard protein
CFE2614_RS15920	COG2990	Protein conserved in bacteria
CFE2614_RS15925	COG1702	phosphate starvation-inducible protein PhoH
CFE2614_RS15945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFE2614_RS15950	COG0506	proline dehydrogenase activity
CFE2614_RS15950	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CFE2614_RS15950	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CFE2614_RS15955	COG3755	Protein conserved in bacteria
CFE2614_RS15960	COG1309	transcriptional regulator
CFE2614_RS15970	COG3729	General stress protein
CFE2614_RS15990	COG0640	Transcriptional regulator
CFE2614_RS16010	COG0577	efflux transmembrane transporter activity
CFE2614_RS16010	COG1136	(ABC) transporter
CFE2614_RS16020	COG1136	(ABC) transporter
CFE2614_RS16020	COG0577	efflux transmembrane transporter activity
CFE2614_RS16035	COG0672	)-iron permease
CFE2614_RS16045	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CFE2614_RS16050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFE2614_RS16055	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFE2614_RS16055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFE2614_RS16105	COG0813	purine-nucleoside phosphorylase activity
CFE2614_RS16125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFE2614_RS16130	COG1120	ATPase activity
CFE2614_RS16140	COG0723	plastoquinol--plastocyanin reductase activity
CFE2614_RS16145	COG2857	Cytochrome c1
CFE2614_RS16145	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CFE2614_RS16165	COG0210	DNA helicase
CFE2614_RS16320	COG0670	Belongs to the BI1 family
CFE2614_RS16345	COG1832	CoA-binding protein
CFE2614_RS16360	COG0210	DNA helicase
CFE2614_RS16365	COG3304	Inner membrane component domain
CFE2614_RS16370	COG1289	transmembrane transporter activity
CFE2614_RS16375	COG3070	regulator of competence-specific genes
CFE2614_RS16395	COG1067	ATP-dependent peptidase activity
CFE2614_RS16405	COG3130	regulation of translation
CFE2614_RS16410	COG3009	Protein conserved in bacteria
CFE2614_RS16415	COG3008	intermembrane lipid transfer
CFE2614_RS16415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CFE2614_RS16420	COG2995	paraquat-inducible protein a
CFE2614_RS16425	COG0488	(ABC) transporter
CFE2614_RS16435	COG0633	Ferredoxin
CFE2614_RS16435	COG3217	Mosc domain protein beta barrel domain protein
CFE2614_RS16450	COG0431	NADPH-dependent FMN reductase
CFE2614_RS16455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFE2614_RS16465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFE2614_RS16470	COG1116	anion transmembrane transporter activity
CFE2614_RS16475	COG0308	aminopeptidase N
CFE2614_RS16650	COG3772	lysozyme
CFE2614_RS16750	COG0582	viral genome integration into host DNA
CFE2614_RS16770	COG1448	Aminotransferase
CFE2614_RS16775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFE2614_RS16780	COG3108	Peptidase M15
CFE2614_RS16785	COG2989	Protein conserved in bacteria
CFE2614_RS16795	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CFE2614_RS16805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFE2614_RS16810	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CFE2614_RS16815	COG3173	Aminoglycoside phosphotransferase
CFE2614_RS16830	COG3214	Protein conserved in bacteria
CFE2614_RS16845	COG0658	competence protein
CFE2614_RS16845	COG2333	competence protein COMEC
CFE2614_RS16850	COG0776	regulation of translation
CFE2614_RS16855	COG0539	negative regulation of cytoplasmic translation
CFE2614_RS16865	COG0501	Belongs to the peptidase M48B family
CFE2614_RS16880	COG2323	membrane
CFE2614_RS16885	COG1944	ATP diphosphatase activity
CFE2614_RS16890	COG2116	formate transmembrane transporter activity
CFE2614_RS16895	COG1882	Formate acetyltransferase
CFE2614_RS17035	COG4695	Portal protein
CFE2614_RS17085	COG4974	Belongs to the 'phage' integrase family
CFE2614_RS17090	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CFE2614_RS17095	COG0531	amino acid
CFE2614_RS17105	COG1335	isochorismatase
CFE2614_RS17110	COG3302	dmso reductase anchor subunit
CFE2614_RS17115	COG0437	4 iron, 4 sulfur cluster binding
CFE2614_RS17120	COG0243	molybdopterin cofactor binding
CFE2614_RS17130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFE2614_RS17140	COG1674	ftsk spoiiie
CFE2614_RS17140	COG1178	ABC-type Fe3 transport system permease component
CFE2614_RS17150	COG0492	ferredoxin-NADP+ reductase activity
CFE2614_RS17155	COG4988	ABC transporter
CFE2614_RS17160	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CFE2614_RS17175	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFE2614_RS17180	COG0583	DNA-binding transcription factor activity
CFE2614_RS17190	COG1335	isochorismatase
CFE2614_RS17210	COG1177	transmembrane transport
CFE2614_RS17215	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFE2614_RS17220	COG3842	ATPase activity
CFE2614_RS17225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CFE2614_RS17285	COG0583	DNA-binding transcription factor activity
CFE2614_RS17290	COG3226	Transcriptional regulator
CFE2614_RS17295	COG0738	Major facilitator superfamily
CFE2614_RS17300	COG0561	phosphatase activity
CFE2614_RS17310	COG2814	Major facilitator Superfamily
CFE2614_RS17315	COG0671	phosphoesterase, PA-phosphatase related
CFE2614_RS17320	COG1349	DNA-binding transcription factor activity
CFE2614_RS17325	COG1686	Belongs to the peptidase S11 family
CFE2614_RS17330	COG0625	glutathione transferase activity
CFE2614_RS17335	COG2133	pyrroloquinoline quinone binding
CFE2614_RS17450	COG1446	asparaginase
CFE2614_RS17460	COG0303	'Molybdopterin
CFE2614_RS17465	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CFE2614_RS17470	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFE2614_RS17475	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CFE2614_RS17480	COG1882	Formate acetyltransferase
CFE2614_RS17485	COG0561	phosphatase activity
CFE2614_RS17495	COG0488	(ABC) transporter
CFE2614_RS17500	COG1376	ErfK ybiS ycfS ynhG family protein
CFE2614_RS17505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CFE2614_RS17520	COG2194	sulfuric ester hydrolase activity
CFE2614_RS17525	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CFE2614_RS17540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFE2614_RS17545	COG0765	amino acid transport
CFE2614_RS17550	COG1126	abc transporter atp-binding protein
CFE2614_RS17555	COG0668	transmembrane transport
CFE2614_RS17570	COG4774	siderophore transport
CFE2614_RS17580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CFE2614_RS17590	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFE2614_RS17595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFE2614_RS17605	COG0471	metal ion transport
CFE2614_RS17615	COG2188	Transcriptional regulator
CFE2614_RS17620	COG0513	Belongs to the DEAD box helicase family
CFE2614_RS17625	COG1309	transcriptional regulator
CFE2614_RS17635	COG1131	(ABC) transporter
CFE2614_RS17640	COG0842	Transport permease protein
CFE2614_RS17645	COG0842	Transport permease protein
CFE2614_RS17655	COG3568	Endonuclease Exonuclease Phosphatase
CFE2614_RS17660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFE2614_RS17665	COG0392	lysyltransferase activity
CFE2614_RS17670	COG0670	Belongs to the BI1 family
CFE2614_RS17675	COG0314	molybdopterin synthase activity
CFE2614_RS17680	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CFE2614_RS17690	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFE2614_RS17720	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CFE2614_RS17740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFE2614_RS17745	COG1881	PFAM PEBP family protein
CFE2614_RS17775	COG4677	pectinesterase activity
CFE2614_RS17790	COG0561	phosphatase activity
CFE2614_RS17800	COG4149	molybdate abc transporter
CFE2614_RS17805	COG0725	ABC transporter, periplasmic molybdate-binding protein
CFE2614_RS17815	COG3585	molybdate ion transport
CFE2614_RS17815	COG2005	Transcriptional regulator
CFE2614_RS17820	COG1119	ATPase activity
CFE2614_RS17825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFE2614_RS17830	COG1085	galactose-1-phosphate uridylyltransferase
CFE2614_RS17840	COG2017	converts alpha-aldose to the beta-anomer
CFE2614_RS17850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFE2614_RS17860	COG1230	cation diffusion facilitator family transporter
CFE2614_RS17865	COG3201	nicotinamide mononucleotide transporter
CFE2614_RS17905	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CFE2614_RS17910	COG2885	chlorophyll binding
CFE2614_RS17920	COG3064	Membrane
CFE2614_RS17925	COG0848	biopolymer transport protein
CFE2614_RS17930	COG0811	peptide transport
CFE2614_RS17935	COG0824	Thioesterase
CFE2614_RS17940	COG3790	cyd operon protein YbgE
CFE2614_RS17945	COG4890	Cyd operon protein YbgT
CFE2614_RS17950	COG1294	oxidase, subunit
CFE2614_RS17955	COG1271	oxidase subunit
CFE2614_RS17960	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFE2614_RS17970	COG4865	methylaspartate mutase activity
CFE2614_RS17975	COG3799	methylaspartate ammonia-lyase activity
CFE2614_RS17990	COG1301	dicarboxylic acid transport
CFE2614_RS18000	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CFE2614_RS18000	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CFE2614_RS18010	COG0583	DNA-binding transcription factor activity
CFE2614_RS18015	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFE2614_RS18015	COG1648	precorrin-2 dehydrogenase activity
CFE2614_RS18025	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFE2614_RS18035	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFE2614_RS18040	COG0567	Dehydrogenase, E1 component
CFE2614_RS18045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CFE2614_RS18050	COG1053	succinate dehydrogenase
CFE2614_RS18055	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CFE2614_RS18060	COG2009	succinate dehydrogenase
CFE2614_RS18070	COG3157	Type VI secretion system effector, Hcp
CFE2614_RS18085	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
CFE2614_RS18090	COG3180	Ammonia monooxygenase
CFE2614_RS18120	COG1984	allophanate hydrolase subunit 2
CFE2614_RS18125	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CFE2614_RS18140	COG5464	transposase or invertase
CFE2614_RS18150	COG3272	Protein of unknown function (DUF1722)
CFE2614_RS18180	COG2205	protein histidine kinase activity
CFE2614_RS18185	COG0745	RESPONSE REGULATOR receiver
CFE2614_RS18190	COG0033	Phosphoglucomutase
CFE2614_RS18195	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CFE2614_RS18200	COG0596	Alpha beta hydrolase
CFE2614_RS18210	COG0716	FMN binding
CFE2614_RS18220	COG0735	belongs to the Fur family
CFE2614_RS18225	COG0583	DNA-binding transcription factor activity
CFE2614_RS18230	COG1053	succinate dehydrogenase
CFE2614_RS18265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFE2614_RS18265	COG1263	PTS System
CFE2614_RS18265	COG2190	(PTS) system
CFE2614_RS18275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFE2614_RS18280	COG1846	Transcriptional regulator
CFE2614_RS18280	COG1940	carbohydrate kinase activity
CFE2614_RS18285	COG0647	UMP catabolic process
CFE2614_RS18295	COG0367	asparagine synthase
CFE2614_RS18340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFE2614_RS18355	COG1702	phosphate starvation-inducible protein PhoH
CFE2614_RS18365	COG4535	Mg2 and Co2 transporter CorC
CFE2614_RS18380	COG0765	amino acid transport
CFE2614_RS18385	COG0765	amino acid transport
CFE2614_RS18390	COG1126	abc transporter atp-binding protein
CFE2614_RS18400	COG2888	peptidyl-tyrosine sulfation
CFE2614_RS18415	COG1466	dna polymerase III delta subunit
CFE2614_RS18425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFE2614_RS18435	COG0799	negative regulation of ribosome biogenesis
CFE2614_RS18445	COG0768	penicillin binding
CFE2614_RS18450	COG0772	Belongs to the SEDS family
CFE2614_RS18455	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CFE2614_RS18460	COG1686	Belongs to the peptidase S11 family
CFE2614_RS18485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFE2614_RS18505	COG3069	C4-dicarboxylate transmembrane transporter activity
CFE2614_RS18510	COG4565	transcriptional regulatory protein
CFE2614_RS18515	COG3290	protein histidine kinase activity
CFE2614_RS18520	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CFE2614_RS18530	COG2301	Belongs to the HpcH HpaI aldolase family
CFE2614_RS18535	COG3051	citrate lyase alpha subunit
CFE2614_RS18550	COG0471	metal ion transport
CFE2614_RS18555	COG3719	Belongs to the RNase T2 family
CFE2614_RS18570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFE2614_RS18600	COG3634	alkyl hydroperoxide reductase activity
CFE2614_RS18610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFE2614_RS18615	COG0583	DNA-binding transcription factor activity
CFE2614_RS18620	COG3969	phosphoadenosine phosphosulfate
CFE2614_RS18625	COG1475	DNA binding
CFE2614_RS18630	COG0436	Aminotransferase
CFE2614_RS18635	COG0371	Dehydrogenase
CFE2614_RS18645	COG2879	small protein
CFE2614_RS18650	COG1966	Carbon starvation protein
CFE2614_RS18660	COG1028	Short-chain dehydrogenase reductase Sdr
CFE2614_RS18665	COG3433	isochorismatase activity
CFE2614_RS18665	COG1535	isochorismatase
CFE2614_RS18670	COG1021	2,3-dihydroxybenzoate-AMP ligase
CFE2614_RS18675	COG1169	isochorismate synthase
CFE2614_RS18680	COG4592	Periplasmic binding protein
CFE2614_RS18690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFE2614_RS18695	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFE2614_RS18700	COG1120	ATPase activity
CFE2614_RS18710	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CFE2614_RS18710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFE2614_RS18715	COG3251	PFAM MbtH domain protein
CFE2614_RS18720	COG2382	esterase
CFE2614_RS18730	COG4771	TonB-dependent receptor
CFE2614_RS18770	COG2315	Protein conserved in bacteria
CFE2614_RS18780	COG0668	transmembrane transport
CFE2614_RS18800	COG2211	Major facilitator Superfamily
CFE2614_RS18805	COG1113	amino acid transport
CFE2614_RS18825	COG3300	MHYT domain
CFE2614_RS18825	COG5001	Diguanylate cyclase
CFE2614_RS18840	COG3059	membrane
CFE2614_RS18850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFE2614_RS18855	COG2207	Transcriptional regulator
CFE2614_RS18860	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFE2614_RS18865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFE2614_RS18870	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFE2614_RS18875	COG1538	Outer membrane efflux protein
CFE2614_RS18880	COG0745	RESPONSE REGULATOR receiver
CFE2614_RS18885	COG5002	protein histidine kinase activity
CFE2614_RS18900	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CFE2614_RS18900	COG0321	lipoyl(octanoyl) transferase activity
CFE2614_RS18905	COG0243	molybdopterin cofactor binding
CFE2614_RS18935	COG3005	denitrification pathway
CFE2614_RS18940	COG0745	RESPONSE REGULATOR receiver
CFE2614_RS18945	COG1879	ABC-type sugar transport system periplasmic component
CFE2614_RS18950	COG2205	protein histidine kinase activity
CFE2614_RS18950	COG2198	Histidine kinase
CFE2614_RS18950	COG0784	Response regulator, receiver
CFE2614_RS19010	COG2501	S4 domain
CFE2614_RS19015	COG1988	membrane-bound metal-dependent
CFE2614_RS19025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFE2614_RS19035	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFE2614_RS19040	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFE2614_RS19045	COG0549	Belongs to the carbamate kinase family
CFE2614_RS19055	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFE2614_RS19060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFE2614_RS19065	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFE2614_RS19070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFE2614_RS19075	COG3257	ureidoglycine aminohydrolase activity
CFE2614_RS19080	COG1929	Belongs to the glycerate kinase type-1 family
CFE2614_RS19085	COG2233	PERMEase
CFE2614_RS19095	COG1953	Uracil, thiamine, allantoin
CFE2614_RS19105	COG2084	Dehydrogenase
CFE2614_RS19110	COG3622	Belongs to the hyi family
CFE2614_RS19115	COG3960	tartronate-semialdehyde synthase activity
CFE2614_RS19150	COG1464	Belongs to the NlpA lipoprotein family
CFE2614_RS19155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFE2614_RS19160	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CFE2614_RS19165	COG4181	ATPase activity
CFE2614_RS19170	COG2755	lipolytic protein G-D-S-L family
CFE2614_RS19175	COG0300	oxidoreductase activity
CFE2614_RS19180	COG3118	belongs to the thioredoxin family
CFE2614_RS19185	COG0390	transport system, permease component
CFE2614_RS19190	COG4619	ABC transporter
CFE2614_RS19195	COG0330	HflC and HflK could
CFE2614_RS19200	COG1585	Membrane protein implicated in regulation of membrane protease activity
CFE2614_RS19220	COG4771	TonB-dependent receptor
CFE2614_RS19225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CFE2614_RS19235	COG3721	Heme iron utilization protein
CFE2614_RS19245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFE2614_RS19255	COG2217	Heavy metal translocating P-type atpase
CFE2614_RS19260	COG3735	TraB family
CFE2614_RS19265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFE2614_RS19275	COG2223	nitrite transmembrane transporter activity
CFE2614_RS19280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFE2614_RS19280	COG4651	solute:proton antiporter activity
CFE2614_RS19285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFE2614_RS19330	COG2832	Protein of unknown function (DUF454)
CFE2614_RS19335	COG3923	Primosomal replication protein n
CFE2614_RS19345	COG3264	Mechanosensitive ion channel
CFE2614_RS19345	COG1196	nuclear chromosome segregation
CFE2614_RS19350	COG1309	transcriptional regulator
CFE2614_RS19355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFE2614_RS19360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFE2614_RS19375	COG0110	maltose O-acetyltransferase activity
CFE2614_RS19395	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CFE2614_RS19400	COG5507	3-demethylubiquinone-9 3-methyltransferase
CFE2614_RS19405	COG2364	Membrane
CFE2614_RS19410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFE2614_RS19430	COG3695	enzyme binding
CFE2614_RS19435	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CFE2614_RS19440	COG1946	Acyl-CoA thioesterase
CFE2614_RS19445	COG0004	ammonium transporteR
CFE2614_RS19450	COG0347	Belongs to the P(II) protein family
CFE2614_RS19460	COG1132	(ABC) transporter
CFE2614_RS19465	COG1132	(ABC) transporter
CFE2614_RS19470	COG1522	sequence-specific DNA binding
CFE2614_RS19490	COG4533	DNA binding
CFE2614_RS19500	COG0824	Thioesterase
CFE2614_RS19505	COG1555	photosystem II stabilization
CFE2614_RS19510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFE2614_RS19515	COG0776	regulation of translation
CFE2614_RS19520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFE2614_RS19545	COG0271	Belongs to the BolA IbaG family
CFE2614_RS19555	COG3056	Lipoprotein
CFE2614_RS19560	COG2223	nitrite transmembrane transporter activity
CFE2614_RS19565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFE2614_RS19570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFE2614_RS19575	COG1845	cytochrome c oxidase, subunit III
CFE2614_RS19580	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CFE2614_RS19590	COG2814	Major facilitator Superfamily
CFE2614_RS19625	COG0142	geranyltranstransferase activity
CFE2614_RS19635	COG0667	Aldo Keto reductase
CFE2614_RS19640	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CFE2614_RS19645	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CFE2614_RS19660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFE2614_RS19660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFE2614_RS19670	COG4238	major outer membrane lipoprotein
CFE2614_RS19690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFE2614_RS19695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFE2614_RS19700	COG1862	Preprotein translocase
CFE2614_RS19710	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFE2614_RS19720	COG0450	alkyl hydroperoxide reductase
CFE2614_RS19725	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CFE2614_RS19735	COG1335	isochorismatase
CFE2614_RS19740	COG0583	DNA-binding transcription factor activity
CFE2614_RS19745	COG0366	Alpha amylase catalytic
CFE2614_RS19765	COG5002	protein histidine kinase activity
CFE2614_RS19775	COG0420	3'-5' exonuclease activity
CFE2614_RS19780	COG0419	ATPase involved in DNA repair
CFE2614_RS19785	COG2814	Major facilitator Superfamily
CFE2614_RS19790	COG1940	carbohydrate kinase activity
CFE2614_RS19805	COG4126	flavin adenine dinucleotide binding
CFE2614_RS19825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CFE2614_RS19830	COG3706	GGDEF domain
CFE2614_RS19840	COG1785	Belongs to the alkaline phosphatase family
CFE2614_RS19855	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFE2614_RS19875	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CFE2614_RS19880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CFE2614_RS19885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFE2614_RS19900	COG0113	porphobilinogen synthase activity
CFE2614_RS19905	COG2175	clavaminate synthase activity
CFE2614_RS19910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFE2614_RS19915	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CFE2614_RS19920	COG4521	taurine ABC transporter
CFE2614_RS19935	COG2271	Major facilitator Superfamily
CFE2614_RS19940	COG1840	ABC-type Fe3 transport system, periplasmic component
CFE2614_RS19950	COG3842	ATPase activity
CFE2614_RS19955	COG2040	homocysteine
CFE2614_RS19960	COG0833	amino acid
CFE2614_RS19965	COG2814	Major facilitator Superfamily
CFE2614_RS20000	COG1414	Transcriptional regulator
CFE2614_RS20030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CFE2614_RS20045	COG1609	Transcriptional regulator
CFE2614_RS20060	COG0110	maltose O-acetyltransferase activity
CFE2614_RS20070	COG2079	MmgE PrpD family protein
CFE2614_RS20075	COG0372	Belongs to the citrate synthase family
CFE2614_RS20085	COG3829	transcription factor binding
CFE2614_RS20095	COG1280	lysine exporter protein (LysE YggA)
CFE2614_RS20100	COG3706	GGDEF domain
CFE2614_RS20105	COG0348	domain, Protein
CFE2614_RS20110	COG1737	Transcriptional regulator
CFE2614_RS20120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFE2614_RS20125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFE2614_RS20130	COG1120	ATPase activity
CFE2614_RS20135	COG4774	siderophore transport
CFE2614_RS20155	COG0583	DNA-binding transcription factor activity
CFE2614_RS20175	COG3069	C4-dicarboxylate transmembrane transporter activity
CFE2614_RS20180	COG2195	Cleaves the N-terminal amino acid of tripeptides
CFE2614_RS20190	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CFE2614_RS20195	COG0693	protein deglycase activity
CFE2614_RS20200	COG2957	Belongs to the agmatine deiminase family
CFE2614_RS20205	COG2200	EAL domain
CFE2614_RS20215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFE2614_RS20220	COG0531	amino acid
CFE2614_RS20225	COG0174	glutamine synthetase
CFE2614_RS20230	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFE2614_RS20235	COG1396	sequence-specific DNA binding
CFE2614_RS20235	COG1917	Cupin 2, conserved barrel domain protein
CFE2614_RS20240	COG1012	belongs to the aldehyde dehydrogenase family
CFE2614_RS20245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFE2614_RS20260	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CFE2614_RS20265	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CFE2614_RS20270	COG1999	signal sequence binding
CFE2614_RS20275	COG1773	rubredoxin
CFE2614_RS20280	COG1271	oxidase subunit
CFE2614_RS20285	COG1294	oxidase, subunit
CFE2614_RS20315	COG1757	Na H antiporter
CFE2614_RS20320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CFE2614_RS20335	COG0582	viral genome integration into host DNA
CFE2614_RS20355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFE2614_RS20375	COG4372	Transposase
CFE2614_RS20380	COG3436	PFAM IS66 Orf2 family protein
CFE2614_RS20425	COG2826	transposase and inactivated derivatives, IS30 family
CFE2614_RS20430	COG2963	transposase activity
CFE2614_RS20445	COG3596	GTP binding
CFE2614_RS20455	COG2378	regulation of single-species biofilm formation
CFE2614_RS20490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFE2614_RS20505	COG2003	Belongs to the UPF0758 family
CFE2614_RS20660	COG1783	phage Terminase large subunit
CFE2614_RS20690	COG3179	chitinase
CFE2614_RS20720	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CFE2614_RS20760	COG0305	Participates in initiation and elongation during chromosome replication
CFE2614_RS20780	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFE2614_RS20805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFE2614_RS20815	COG0629	single-stranded DNA binding
CFE2614_RS20825	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CFE2614_RS20840	COG0582	viral genome integration into host DNA
CFE2614_RS20855	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CFE2614_RS20895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFE2614_RS20905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFE2614_RS20930	COG2195	Cleaves the N-terminal amino acid of tripeptides
CFE2614_RS20955	COG0791	NLP P60 protein
CFE2614_RS20960	COG3034	peptidoglycan biosynthetic process
CFE2614_RS20965	COG0121	glutamine amidotransferase
CFE2614_RS20975	COG1960	acyl-CoA dehydrogenase activity
CFE2614_RS20980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFE2614_RS20990	COG2200	EAL domain
CFE2614_RS21005	COG3539	Fimbrial protein
CFE2614_RS21015	COG3121	Chaperone
CFE2614_RS21020	COG3188	usher protein
CFE2614_RS21030	COG3539	Fimbrial protein
CFE2614_RS21035	COG0745	RESPONSE REGULATOR receiver
CFE2614_RS21050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFE2614_RS21060	COG2226	methyltransferase
CFE2614_RS21070	COG0741	lytic transglycosylase activity
CFE2614_RS21070	COG1388	LysM domain
CFE2614_RS21075	COG2226	methyltransferase
CFE2614_RS21085	COG2814	Major facilitator Superfamily
CFE2614_RS21090	COG0583	DNA-binding transcription factor activity
CFE2614_RS21125	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CFE2614_RS21135	COG2011	ABC-type metal ion transport system permease component
CFE2614_RS21140	COG1464	Belongs to the NlpA lipoprotein family
CFE2614_RS21150	COG1720	tRNA m6t6A37 methyltransferase activity
CFE2614_RS21160	COG3015	lipoprotein NlpE involved in copper resistance
CFE2614_RS21165	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CFE2614_RS21180	COG4568	rho-dependent transcription termination
CFE2614_RS21190	COG0346	lactoylglutathione lyase activity
CFE2614_RS21195	COG1982	Orn Lys Arg decarboxylase major
CFE2614_RS21230	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFE2614_RS21235	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CFE2614_RS21250	COG0575	Belongs to the CDS family
CFE2614_RS21260	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CFE2614_RS21305	COG3835	regulator
CFE2614_RS21330	COG2860	membrane
CFE2614_RS21355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CFE2614_RS21360	COG1120	ATPase activity
CFE2614_RS21365	COG4774	siderophore transport
CFE2614_RS21370	COG3539	Fimbrial protein
CFE2614_RS21375	COG3188	usher protein
CFE2614_RS21380	COG3121	Chaperone
CFE2614_RS21395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFE2614_RS21400	COG1643	Atp-dependent helicase
CFE2614_RS21405	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CFE2614_RS21425	COG0617	tRNA 3'-terminal CCA addition
CFE2614_RS21430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFE2614_RS21450	COG0726	polysaccharide deacetylase
CFE2614_RS21455	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFE2614_RS21460	COG0842	Transport permease protein
CFE2614_RS21465	COG1131	(ABC) transporter
CFE2614_RS21470	COG0288	reversible hydration of carbon dioxide
CFE2614_RS21475	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CFE2614_RS21505	COG3064	Membrane
CFE2614_RS21520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFE2614_RS21525	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFE2614_RS21530	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CFE2614_RS21545	COG2211	Major facilitator Superfamily
CFE2614_RS21550	COG3940	Belongs to the glycosyl hydrolase 43 family
CFE2614_RS21555	COG3725	Membrane protein required for beta-lactamase induction
CFE2614_RS21570	COG4969	Belongs to the N-Me-Phe pilin family
CFE2614_RS21575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CFE2614_RS21580	COG1459	type II secretion system
CFE2614_RS21590	COG0237	dephospho-CoA kinase activity
CFE2614_RS21605	COG0494	nUDIX hydrolase
CFE2614_RS21625	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFE2614_RS21630	COG0849	cell division
CFE2614_RS21640	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFE2614_RS21655	COG0772	Belongs to the SEDS family
CFE2614_RS21660	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFE2614_RS21670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CFE2614_RS21675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFE2614_RS21680	COG0768	penicillin binding
CFE2614_RS21710	COG0028	Belongs to the TPP enzyme family
CFE2614_RS21745	COG1609	Transcriptional regulator
CFE2614_RS21755	COG1028	Short-chain dehydrogenase reductase Sdr
CFE2614_RS21760	COG2814	Major facilitator Superfamily
CFE2614_RS21780	COG1178	ABC-type Fe3 transport system permease component
CFE2614_RS21790	COG0586	Pfam SNARE associated Golgi protein
CFE2614_RS21810	COG0235	Class ii aldolase
CFE2614_RS21820	COG0417	DNA replication proofreading
CFE2614_RS21830	COG0564	pseudouridine synthase activity
CFE2614_RS21840	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CFE2614_RS21890	COG2271	Major facilitator Superfamily
CFE2614_RS21900	COG0644	oxidoreductase
CFE2614_RS21960	COG0505	Belongs to the CarA family
CFE2614_RS21980	COG1047	Peptidyl-prolyl cis-trans
CFE2614_RS21995	COG0196	riboflavin kinase activity
CFE2614_RS22020	COG0583	DNA-binding transcription factor activity
CFE2614_RS22035	COG0641	radical SAM
CFE2614_RS22040	COG3119	arylsulfatase activity
CFE2614_RS22055	COG0443	Heat shock 70 kDa protein
CFE2614_RS22065	COG4735	regulation of single-species biofilm formation
CFE2614_RS22070	COG1584	GPR1 FUN34 yaaH family protein
CFE2614_RS22080	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFE2614_RS22090	COG1115	amino acid carrier protein
CFE2614_RS22100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CFE2614_RS22110	COG0460	homoserine dehydrogenase
CFE2614_RS22110	COG0527	aspartate kinase activity
CFE2614_RS22120	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CFE2614_RS22130	COG0745	RESPONSE REGULATOR receiver
CFE2614_RS22135	COG4452	Inner membrane protein CreD
CFE2614_RS22140	COG2205	protein histidine kinase activity
CFE2614_RS22145	COG0745	RESPONSE REGULATOR receiver
CFE2614_RS22150	COG3045	CreA protein
CFE2614_RS22155	COG2207	Transcriptional regulator
CFE2614_RS22155	COG3708	Transcriptional regulator
CFE2614_RS22175	COG0741	lytic transglycosylase activity
CFE2614_RS22180	COG0488	(ABC) transporter
CFE2614_RS22195	COG0560	Phosphoserine phosphatase
CFE2614_RS22205	COG3726	membrane protein affecting hemolysin expression
CFE2614_RS22235	COG1328	CTP reductase activity
CFE2614_RS22240	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CFE2614_RS22245	COG0084	hydrolase, TatD family'
CFE2614_RS22250	COG4667	esterase of the alpha-beta hydrolase superfamily
CFE2614_RS22255	COG5487	UPF0391 membrane protein
CFE2614_RS22260	COG2823	Periplasmic or secreted lipoprotein
CFE2614_RS22270	COG1011	Hydrolase
CFE2614_RS22275	COG0456	acetyltransferase
CFE2614_RS22280	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CFE2614_RS22310	COG3706	GGDEF domain
CFE2614_RS22315	COG4114	ferric iron reductase
CFE2614_RS22320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CFE2614_RS22325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFE2614_RS22330	COG2197	response regulator
CFE2614_RS22335	COG2197	response regulator
CFE2614_RS22340	COG2966	Psort location CytoplasmicMembrane, score
CFE2614_RS22355	COG1484	DNA-dependent DNA replication
CFE2614_RS22375	COG1063	alcohol dehydrogenase
CFE2614_RS22380	COG1802	Transcriptional regulator
CFE2614_RS22385	COG2271	Major facilitator Superfamily
CFE2614_RS22395	COG0840	transmembrane signaling receptor activity
CFE2614_RS22400	COG1966	Carbon starvation protein
CFE2614_RS22405	COG2879	small protein
CFE2614_RS22410	COG0523	cobalamin synthesis protein
CFE2614_RS22420	COG1566	PFAM secretion protein HlyD family protein
CFE2614_RS22430	COG5457	Domain of unknown function (DUF1127)
CFE2614_RS22435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFE2614_RS22440	COG5464	transposase or invertase
CFE2614_RS22465	COG0626	cystathionine gamma-synthase activity
CFE2614_RS22470	COG1301	dicarboxylic acid transport
CFE2614_RS22475	COG0583	DNA-binding transcription factor activity
CFE2614_RS22480	COG2733	membrane
CFE2614_RS22490	COG0477	Major facilitator Superfamily
CFE2614_RS22495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFE2614_RS22505	COG2186	Transcriptional regulator
CFE2614_RS22510	COG0246	Mannitol dehydrogenase
CFE2614_RS22520	COG2610	gluconate transmembrane transporter activity
CFE2614_RS22525	COG1556	Lactate utilization protein
CFE2614_RS22530	COG1139	Iron-sulfur cluster binding protein
CFE2614_RS22535	COG0247	lactate metabolic process
CFE2614_RS22540	COG1620	l-lactate permease
CFE2614_RS22580	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFE2614_RS22640	COG0582	viral genome integration into host DNA
CFE2614_RS22650	COG1064	alcohol dehydrogenase
CFE2614_RS22655	COG0433	COG0433 Predicted ATPase
CFE2614_RS22660	COG0795	lipopolysaccharide-transporting ATPase activity
CFE2614_RS22665	COG0795	lipopolysaccharide-transporting ATPase activity
CFE2614_RS22680	COG2927	DNA polymerase III (CHI subunit)
CFE2614_RS22685	COG0525	valine-tRNA ligase activity
CFE2614_RS22715	COG2731	YhcH YjgK YiaL family protein
CFE2614_RS22720	COG2235	arginine
CFE2614_RS22730	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFE2614_RS22735	COG1288	antiporter activity
CFE2614_RS22740	COG1438	arginine binding
CFE2614_RS22785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFE2614_RS22805	COG1263	PTS System
CFE2614_RS22805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFE2614_RS22810	COG0366	Alpha amylase catalytic
CFE2614_RS22820	COG1737	Transcriptional regulator
CFE2614_RS22825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS22830	COG0383	alpha-mannosidase activity
CFE2614_RS22835	COG0366	Alpha amylase catalytic
CFE2614_RS22840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS22840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS22840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFE2614_RS22855	COG2026	Addiction module toxin, RelE StbE family
CFE2614_RS22860	COG3077	Addiction module antitoxin, RelB DinJ family
CFE2614_RS22865	COG3711	transcriptional antiterminator
CFE2614_RS22865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFE2614_RS22880	COG3964	amidohydrolase
CFE2614_RS22915	COG0312	modulator of DNA gyrase
CFE2614_RS22925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFE2614_RS22940	COG0840	transmembrane signaling receptor activity
CFE2614_RS22945	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFE2614_RS22950	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFE2614_RS22955	COG1129	ABC transporter
CFE2614_RS22960	COG1879	ABC-type sugar transport system periplasmic component
CFE2614_RS22970	COG2105	PFAM AIG2 family protein
CFE2614_RS22975	COG2911	Protein conserved in bacteria
CFE2614_RS22980	COG0729	surface antigen
CFE2614_RS22990	COG1253	flavin adenine dinucleotide binding
CFE2614_RS23005	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CFE2614_RS23010	COG1218	3'(2'),5'-bisphosphate nucleotidase
CFE2614_RS23020	COG1733	regulation of RNA biosynthetic process
CFE2614_RS23025	COG0702	epimerase
CFE2614_RS23035	COG0697	spore germination
CFE2614_RS23040	COG0840	transmembrane signaling receptor activity
CFE2614_RS23050	COG1113	amino acid transport
CFE2614_RS23055	COG0545	Peptidyl-prolyl cis-trans isomerase
CFE2614_RS23060	COG3061	Opacity-associated protein A
CFE2614_RS23075	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFE2614_RS23090	COG0730	response to heat
CFE2614_RS23140	COG1073	alpha beta
CFE2614_RS23145	COG3650	response to hydrogen peroxide
CFE2614_RS23155	COG1960	acyl-CoA dehydrogenase activity
CFE2614_RS23160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFE2614_RS23165	COG0557	exoribonuclease II activity
CFE2614_RS23185	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CFE2614_RS23190	COG0330	HflC and HflK could
CFE2614_RS23195	COG0330	HflC and HflK could
CFE2614_RS23200	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFE2614_RS23205	COG1923	regulation of RNA biosynthetic process
CFE2614_RS23220	COG0860	N-Acetylmuramoyl-L-alanine amidase
CFE2614_RS23225	COG0802	atpase or kinase
CFE2614_RS23230	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CFE2614_RS23230	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFE2614_RS23235	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFE2614_RS23270	COG3264	Mechanosensitive ion channel
CFE2614_RS23270	COG1511	domain protein
CFE2614_RS23285	COG1053	succinate dehydrogenase
CFE2614_RS23290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CFE2614_RS23345	COG1509	lysine 2,3-aminomutase activity
CFE2614_RS23370	COG0531	amino acid
CFE2614_RS23375	COG3030	protein affecting phage T7 exclusion by the F plasmid
CFE2614_RS23380	COG1027	Aspartate ammonia-lyase
CFE2614_RS23385	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CFE2614_RS23400	COG1309	transcriptional regulator
CFE2614_RS23410	COG0318	PFAM AMP-dependent synthetase and ligase
CFE2614_RS23440	COG3290	protein histidine kinase activity
CFE2614_RS23445	COG4565	transcriptional regulatory protein
CFE2614_RS23450	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CFE2614_RS23455	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CFE2614_RS23455	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CFE2614_RS23460	COG3647	Membrane
CFE2614_RS23470	COG2211	Major facilitator Superfamily
CFE2614_RS23475	COG1486	melibiose metabolic process
CFE2614_RS23480	COG2169	Transcriptional regulator
CFE2614_RS23485	COG1982	Orn Lys Arg decarboxylase major
CFE2614_RS23490	COG2207	Transcriptional regulator
CFE2614_RS23495	COG0531	amino acid
CFE2614_RS23535	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CFE2614_RS23540	COG2824	Alkylphosphonate utilization operon protein PhnA
CFE2614_RS23545	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CFE2614_RS23550	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CFE2614_RS23555	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CFE2614_RS23560	COG3639	organic phosphonate transmembrane transporter activity
CFE2614_RS23565	COG2188	Transcriptional regulator
CFE2614_RS23570	COG3624	Phosphonate C-P lyase system protein PhnG
CFE2614_RS23575	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CFE2614_RS23580	COG3626	phosphonate metabolism
CFE2614_RS23585	COG3627	carbon phosphorus lyase activity
CFE2614_RS23590	COG4107	phosphonate C-P lyase system protein PhnK
CFE2614_RS23595	COG4778	phosphonate C-P lyase system protein PhnL
CFE2614_RS23600	COG3454	Phosphonate metabolism
CFE2614_RS23610	COG0456	acetyltransferase
CFE2614_RS23615	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CFE2614_RS23635	COG1129	ABC transporter
CFE2614_RS23640	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFE2614_RS23670	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CFE2614_RS23680	COG1566	PFAM secretion protein HlyD family protein
CFE2614_RS23685	COG1289	transmembrane transporter activity
CFE2614_RS23690	COG1538	Outer membrane efflux protein
CFE2614_RS23700	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CFE2614_RS23705	COG1301	dicarboxylic acid transport
CFE2614_RS23710	COG4235	cytochrome complex assembly
CFE2614_RS23715	COG3088	subunit of a heme lyase
CFE2614_RS23720	COG1138	Cytochrome C-type biogenesis protein
CFE2614_RS23725	COG3301	Polysulphide reductase, NrfD
CFE2614_RS23730	COG0437	4 iron, 4 sulfur cluster binding
CFE2614_RS23735	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CFE2614_RS23750	COG3162	membrane
CFE2614_RS23770	COG0629	single-stranded DNA binding
CFE2614_RS23780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFE2614_RS23785	COG2315	Protein conserved in bacteria
CFE2614_RS23790	COG3700	Belongs to the class B bacterial acid phosphatase family
CFE2614_RS23795	COG1448	Aminotransferase
CFE2614_RS23805	COG0305	Participates in initiation and elongation during chromosome replication
CFE2614_RS23820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFE2614_RS23830	COG0735	belongs to the Fur family
CFE2614_RS23835	COG3237	CsbD-like
CFE2614_RS23840	COG0534	Mate efflux family protein
CFE2614_RS23855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CFE2614_RS23890	COG2182	Extracellular solute-binding protein
CFE2614_RS23905	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CFE2614_RS23910	COG1757	Na H antiporter
CFE2614_RS23915	COG3223	Belongs to the PsiE family
CFE2614_RS23920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFE2614_RS23925	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFE2614_RS23950	COG0527	aspartate kinase activity
CFE2614_RS23955	COG3541	Predicted nucleotidyltransferase
CFE2614_RS23965	COG4650	regulator
CFE2614_RS23985	COG0561	phosphatase activity
CFE2614_RS24000	COG1187	pseudouridine synthase activity
CFE2614_RS24040	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFE2614_RS24055	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFE2614_RS24080	COG0646	methionine synthase
CFE2614_RS24080	COG1410	methionine synthase
CFE2614_RS24090	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CFE2614_RS24100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CFE2614_RS24110	COG0456	acetyltransferase
CFE2614_RS24135	COG0151	Belongs to the GarS family
CFE2614_RS24145	COG4191	Histidine kinase
CFE2614_RS24205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CFE2614_RS24210	COG2104	thiamine diphosphate biosynthetic process
CFE2614_RS24225	COG1278	Cold shock
CFE2614_RS24235	COG1447	Phosphotransferase system cellobiose-specific component IIA
CFE2614_RS24270	COG0250	Participates in transcription elongation, termination and antitermination
CFE2614_RS24320	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CFE2614_RS24380	COG0583	DNA-binding transcription factor activity
CFE2614_RS24420	COG2207	Transcriptional regulator
CFE2614_RS24430	COG0371	Dehydrogenase
CFE2614_RS24440	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CFE2614_RS24450	COG0583	DNA-binding transcription factor activity
CFE2614_RS24460	COG0737	Belongs to the 5'-nucleotidase family
CFE2614_RS24470	COG0460	homoserine dehydrogenase
CFE2614_RS24470	COG0527	aspartate kinase activity
CFE2614_RS24475	COG0626	cystathionine gamma-synthase activity
CFE2614_RS24485	COG2211	Major facilitator Superfamily
CFE2614_RS24500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFE2614_RS24510	COG1609	Transcriptional regulator
CFE2614_RS24520	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CFE2614_RS24535	COG1575	Belongs to the MenA family. Type 1 subfamily
CFE2614_RS24550	COG3074	FtsZ-dependent cytokinesis
CFE2614_RS24555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFE2614_RS24565	COG1494	fructose-1,6-bisphosphatase
CFE2614_RS24575	COG3152	Membrane
CFE2614_RS24590	COG0471	metal ion transport
CFE2614_RS24620	COG3678	ATP-independent chaperone mediated protein folding
CFE2614_RS24625	COG0745	RESPONSE REGULATOR receiver
CFE2614_RS24630	COG2205	protein histidine kinase activity
CFE2614_RS24635	COG2258	MOSC domain
CFE2614_RS24640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFE2614_RS24685	COG1454	alcohol dehydrogenase
CFE2614_RS24700	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CFE2614_RS24710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFE2614_RS24715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS24715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFE2614_RS24720	COG1363	Peptidase, m42
CFE2614_RS24725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFE2614_RS24725	COG3711	transcriptional antiterminator
CFE2614_RS24750	COG3383	formate dehydrogenase (NAD+) activity
CFE2614_RS24750	COG0243	molybdopterin cofactor binding
CFE2614_RS24755	COG0243	molybdopterin cofactor binding
CFE2614_RS24755	COG3383	formate dehydrogenase (NAD+) activity
CFE2614_RS24760	COG0437	4 iron, 4 sulfur cluster binding
CFE2614_RS24765	COG2864	formate dehydrogenase
CFE2614_RS24780	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CFE2614_RS24795	COG0456	acetyltransferase
CFE2614_RS24800	COG1490	D-aminoacyl-tRNA deacylase activity
CFE2614_RS24810	COG1011	Hydrolase
CFE2614_RS24815	COG1349	DNA-binding transcription factor activity
CFE2614_RS24820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFE2614_RS24830	COG3684	Belongs to the aldolase LacD family
CFE2614_RS24840	COG2017	converts alpha-aldose to the beta-anomer
CFE2614_RS24845	COG1501	Belongs to the glycosyl hydrolase 31 family
CFE2614_RS24875	COG3852	Histidine kinase
CFE2614_RS24880	COG2204	response regulator
CFE2614_RS24890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFE2614_RS24910	COG0204	Acyl-transferase
CFE2614_RS24925	COG3084	Protein conserved in bacteria
CFE2614_RS24930	COG0746	molybdenum cofactor guanylyltransferase activity
CFE2614_RS24935	COG1763	Mo-molybdopterin cofactor biosynthetic process
CFE2614_RS24975	COG1739	Uncharacterized protein family UPF0029
CFE2614_RS24995	COG1609	Transcriptional regulator
CFE2614_RS25000	COG1940	carbohydrate kinase activity
CFE2614_RS25025	COG0805	protein transport
CFE2614_RS25075	COG0583	DNA-binding transcription factor activity
CFE2614_RS25080	COG0697	spore germination
CFE2614_RS25085	COG0561	phosphatase activity
CFE2614_RS25090	COG2267	carboxylic ester hydrolase activity
CFE2614_RS25095	COG1280	lysine exporter protein (LysE YggA)
CFE2614_RS25105	COG1280	lysine exporter protein (LysE YggA)
CFE2614_RS25140	COG1011	Hydrolase
CFE2614_RS25185	COG2959	enzyme of heme biosynthesis
CFE2614_RS25190	COG3071	HemY protein
CFE2614_RS25235	COG2244	polysaccharide biosynthetic process
CFE2614_RS25240	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFE2614_RS25245	COG0456	acetyltransferase
CFE2614_RS25250	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CFE2614_RS25270	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFE2614_RS25280	COG3118	belongs to the thioredoxin family
CFE2614_RS25300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFE2614_RS25320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFE2614_RS25330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFE2614_RS25335	COG3978	acetolactate synthase activity
CFE2614_RS25355	COG3085	chromosome segregation
CFE2614_RS25395	COG2186	Transcriptional regulator
CFE2614_RS25400	COG0477	Major facilitator Superfamily
CFE2614_RS25405	COG1609	Transcriptional regulator
CFE2614_RS25410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFE2614_RS25415	COG1879	ABC-type sugar transport system periplasmic component
CFE2614_RS25420	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFE2614_RS25430	COG1869	D-ribose catabolic process
CFE2614_RS25455	COG1522	sequence-specific DNA binding
CFE2614_RS25460	COG0716	FMN binding
CFE2614_RS25475	COG3312	ion transport
CFE2614_RS25500	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFE2614_RS25510	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFE2614_RS25515	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CFE2614_RS25615	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFE2614_RS25620	COG0573	inorganic phosphate transmembrane transporter activity
CFE2614_RS25625	COG0581	inorganic phosphate transmembrane transporter activity
CFE2614_RS25635	COG0704	Plays a role in the regulation of phosphate uptake
CFE2614_RS25640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFE2614_RS25645	COG2252	PERMEase
CFE2614_RS25650	COG0431	NADPH-dependent FMN reductase
CFE2614_RS25655	COG2091	lysine biosynthetic process via aminoadipic acid
CFE2614_RS25690	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CFE2614_RS25715	COG0246	Mannitol dehydrogenase
CFE2614_RS25735	COG3250	beta-galactosidase activity
CFE2614_RS25740	COG1309	transcriptional regulator
CFE2614_RS25745	COG3039	Transposase
CFE2614_RS25770	COG1136	(ABC) transporter
CFE2614_RS25785	COG1309	transcriptional regulator
CFE2614_RS25820	COG0589	response to stress
CFE2614_RS25825	COG0659	secondary active sulfate transmembrane transporter activity
CFE2614_RS25875	COG2826	transposase and inactivated derivatives, IS30 family
CFE2614_RS25885	COG3436	PFAM IS66 Orf2 family protein
CFE2614_RS25890	COG2433	Pfam Transposase IS66
CFE2614_RS25920	COG1121	(ABC) transporter
CFE2614_RS25955	COG2135	peptidase activity
CFE2614_RS26015	COG0629	single-stranded DNA binding
CFE2614_RS26320	COG1349	DNA-binding transcription factor activity
CFE2614_RS26325	COG2084	Dehydrogenase
CFE2614_RS26340	COG5001	Diguanylate cyclase
CFE2614_RS26370	COG2963	transposase activity
CFE2614_RS26380	COG0840	transmembrane signaling receptor activity
CFE2614_RS26385	COG4372	Transposase
CFE2614_RS26390	COG3436	PFAM IS66 Orf2 family protein
CFE2614_RS26480	COG3173	Aminoglycoside phosphotransferase
CFE2614_RS26500	COG1660	Displays ATPase and GTPase activities
CFE2614_RS26550	COG2186	Transcriptional regulator
CFE2614_RS26560	COG0246	Mannitol dehydrogenase
CFE2614_RS26815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFE2614_RS27085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFE2614_RS27155	COG3300	MHYT domain
CFE2614_RS27155	COG5001	Diguanylate cyclase