locus-tag	class	description
HS089_RS00010	COG0592	DNA-directed DNA polymerase activity
HS089_RS00025	COG0561	phosphatase activity
HS089_RS00035	COG0823	Involved in the tonB-independent uptake of proteins
HS089_RS00040	COG5645	(Lipo)protein
HS089_RS00060	COG2149	membrane
HS089_RS00070	COG0641	radical SAM
HS089_RS00080	COG2610	gluconate transmembrane transporter activity
HS089_RS00085	COG0583	DNA-binding transcription factor activity
HS089_RS00095	COG2814	Major facilitator Superfamily
HS089_RS00115	COG0028	Belongs to the TPP enzyme family
HS089_RS00120	COG0440	acetolactate synthase activity
HS089_RS00125	COG1349	DNA-binding transcription factor activity
HS089_RS00135	COG0738	Major facilitator superfamily
HS089_RS00145	COG2197	response regulator
HS089_RS00175	COG3620	sequence-specific DNA binding
HS089_RS00185	COG2723	6-phospho-beta-galactosidase activity
HS089_RS00210	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS089_RS00210	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS089_RS00215	COG3715	PTS system
HS089_RS00220	COG3716	PTS system mannose fructose sorbose family IID component
HS089_RS00235	COG5464	transposase or invertase
HS089_RS00240	COG1464	Belongs to the NlpA lipoprotein family
HS089_RS00245	COG0697	spore germination
HS089_RS00255	COG0604	alcohol dehydrogenase
HS089_RS00260	COG0583	DNA-binding transcription factor activity
HS089_RS00280	COG2771	luxR family
HS089_RS00360	COG0582	viral genome integration into host DNA
HS089_RS00370	COG2211	Major facilitator Superfamily
HS089_RS00375	COG1501	Belongs to the glycosyl hydrolase 31 family
HS089_RS00380	COG3711	transcriptional antiterminator
HS089_RS00385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS00385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS00385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS089_RS00390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS00395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS00395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS00405	COG0191	fructose-bisphosphate aldolase activity
HS089_RS00415	COG2982	Protein involved in outer membrane biogenesis
HS089_RS00420	COG2233	PERMEase
HS089_RS00425	COG0786	glutamate:sodium symporter activity
HS089_RS00430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HS089_RS00435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HS089_RS00440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HS089_RS00460	COG2860	membrane
HS089_RS00465	COG1561	YicC-like family, N-terminal region
HS089_RS00490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HS089_RS00505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HS089_RS00520	COG1519	Transferase
HS089_RS00525	COG0438	transferase activity, transferring glycosyl groups
HS089_RS00530	COG0515	serine threonine protein kinase
HS089_RS00535	COG1442	glycosyl transferase family 8
HS089_RS00540	COG1442	glycosyl transferase family 8
HS089_RS00550	COG0859	PFAM glycosyl transferase family 9
HS089_RS00555	COG1215	transferase activity, transferring glycosyl groups
HS089_RS00560	COG3307	-O-antigen
HS089_RS00570	COG0859	PFAM glycosyl transferase family 9
HS089_RS00580	COG0156	8-amino-7-oxononanoate synthase activity
HS089_RS00590	COG1216	Glycosyl transferase, family 2
HS089_RS00595	COG2861	carbohydrate metabolic process
HS089_RS00600	COG4942	peptidase
HS089_RS00610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HS089_RS00615	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HS089_RS00630	COG1045	serine acetyltransferase
HS089_RS00635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HS089_RS00640	COG2271	Major facilitator Superfamily
HS089_RS00650	COG2186	Transcriptional regulator
HS089_RS00670	COG3722	fumarate hydratase activity
HS089_RS00680	COG2213	PTS system mannitol-specific
HS089_RS00680	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS089_RS00690	COG1566	PFAM secretion protein HlyD family protein
HS089_RS00695	COG0625	glutathione transferase activity
HS089_RS00705	COG3276	selenocysteine insertion sequence binding
HS089_RS00710	COG1454	alcohol dehydrogenase
HS089_RS00715	COG1012	belongs to the aldehyde dehydrogenase family
HS089_RS00725	COG1566	PFAM secretion protein HlyD family protein
HS089_RS00730	COG0583	DNA-binding transcription factor activity
HS089_RS00735	COG3713	MltA-interacting MipA family protein
HS089_RS00745	COG2211	Major facilitator Superfamily
HS089_RS00750	COG1917	Cupin 2, conserved barrel domain protein
HS089_RS00750	COG4977	sequence-specific DNA binding
HS089_RS00755	COG0235	Class ii aldolase
HS089_RS00760	COG3623	hexulose-6-phosphate isomerase
HS089_RS00765	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HS089_RS00770	COG1070	Carbohydrate kinase
HS089_RS00775	COG2271	Major facilitator Superfamily
HS089_RS00785	COG2731	YhcH YjgK YiaL family protein
HS089_RS00795	COG1414	Transcriptional regulator
HS089_RS00800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS089_RS00805	COG3977	Valine--pyruvate aminotransferase
HS089_RS00810	COG0366	Alpha amylase catalytic
HS089_RS00815	COG2992	FlgJ-related protein
HS089_RS00820	COG1609	Transcriptional regulator
HS089_RS00820	COG2207	Transcriptional regulator
HS089_RS00830	COG1070	Carbohydrate kinase
HS089_RS00835	COG4682	membrane
HS089_RS00840	COG3274	enterobacterial common antigen metabolic process
HS089_RS00865	COG1278	Cold shock
HS089_RS00870	COG2944	sequence-specific DNA binding
HS089_RS00885	COG2814	Major facilitator Superfamily
HS089_RS00890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS089_RS00900	COG1609	Transcriptional regulator
HS089_RS00905	COG2885	chlorophyll binding
HS089_RS00910	COG0243	molybdopterin cofactor binding
HS089_RS00915	COG0456	acetyltransferase
HS089_RS00920	COG2818	Glycosylase
HS089_RS00925	COG5571	outer membrane autotransporter
HS089_RS00930	COG2223	nitrite transmembrane transporter activity
HS089_RS00955	COG0747	negative chemotaxis
HS089_RS00960	COG0601	transmembrane transport
HS089_RS00965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HS089_RS00970	COG0444	Belongs to the ABC transporter superfamily
HS089_RS00975	COG4608	Belongs to the ABC transporter superfamily
HS089_RS00980	COG2204	response regulator
HS089_RS00985	COG0814	amino acid
HS089_RS00990	COG0626	cystathionine gamma-synthase activity
HS089_RS01000	COG2199	diguanylate cyclase activity
HS089_RS01000	COG2200	EAL domain
HS089_RS01015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS089_RS01020	COG2200	EAL domain
HS089_RS01025	COG2982	Protein involved in outer membrane biogenesis
HS089_RS01030	COG0477	Major facilitator Superfamily
HS089_RS01035	COG1295	ribonuclease BN
HS089_RS01040	COG0583	DNA-binding transcription factor activity
HS089_RS01045	COG1028	Short-chain dehydrogenase reductase Sdr
HS089_RS01055	COG2200	EAL domain
HS089_RS01060	COG2197	response regulator
HS089_RS01070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HS089_RS01085	COG1858	cytochrome C peroxidase
HS089_RS01095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HS089_RS01100	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HS089_RS01105	COG0339	signal peptide processing
HS089_RS01120	COG1959	2 iron, 2 sulfur cluster binding
HS089_RS01130	COG0589	response to stress
HS089_RS01140	COG0306	phosphate transporter
HS089_RS01145	COG2081	HI0933 family
HS089_RS01210	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS089_RS01240	COG0739	heme binding
HS089_RS01250	COG2132	Multicopper oxidase
HS089_RS01255	COG3667	copper resistance
HS089_RS01260	COG2372	response to copper ion
HS089_RS01265	COG1276	copper resistance
HS089_RS01270	COG0745	RESPONSE REGULATOR receiver
HS089_RS01275	COG2205	protein histidine kinase activity
HS089_RS01290	COG3436	PFAM IS66 Orf2 family protein
HS089_RS01295	COG4372	Transposase
HS089_RS01300	COG2239	Acts as a magnesium transporter
HS089_RS01305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS089_RS01310	COG1129	ABC transporter
HS089_RS01310	COG0842	Transport permease protein
HS089_RS01315	COG0842	Transport permease protein
HS089_RS01335	COG2091	lysine biosynthetic process via aminoadipic acid
HS089_RS01340	COG0628	permease
HS089_RS01345	COG0477	Major facilitator Superfamily
HS089_RS01355	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HS089_RS01370	COG3714	YhhN family
HS089_RS01395	COG3776	membrane
HS089_RS01400	COG0742	ribosomal rna small subunit methyltransferase
HS089_RS01405	COG0552	protein localization to endoplasmic reticulum
HS089_RS01410	COG2884	Cell division ATP-binding protein ftsE
HS089_RS01415	COG2177	Part of the ABC transporter FtsEX involved in
HS089_RS01440	COG0683	leucine binding
HS089_RS01450	COG4177	L-phenylalanine transmembrane transporter activity
HS089_RS01455	COG0411	ABC transporter
HS089_RS01490	COG0584	glycerophosphoryl diester phosphodiesterase
HS089_RS01500	COG0405	Gamma-glutamyltransferase
HS089_RS01505	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HS089_RS01520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS089_RS01530	COG1247	-acetyltransferase
HS089_RS01535	COG0673	inositol 2-dehydrogenase activity
HS089_RS01540	COG1741	Belongs to the pirin family
HS089_RS01545	COG1609	Transcriptional regulator
HS089_RS01550	COG3265	gluconokinase activity
HS089_RS01555	COG2610	gluconate transmembrane transporter activity
HS089_RS01570	COG2095	MarC family integral membrane protein
HS089_RS01575	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HS089_RS01600	COG0058	SHG alpha-glucan phosphorylase activity
HS089_RS01605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HS089_RS01620	COG1349	DNA-binding transcription factor activity
HS089_RS01630	COG0058	SHG alpha-glucan phosphorylase activity
HS089_RS01635	COG1640	4-alpha-glucanotransferase
HS089_RS01640	COG2610	gluconate transmembrane transporter activity
HS089_RS01650	COG1040	competence protein
HS089_RS01675	COG1918	ferrous iron import across plasma membrane
HS089_RS01680	COG2183	response to ionizing radiation
HS089_RS01685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HS089_RS01715	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HS089_RS01725	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HS089_RS01730	COG1011	Hydrolase
HS089_RS01740	COG0494	nUDIX hydrolase
HS089_RS01745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HS089_RS01750	COG4972	Pilus assembly protein
HS089_RS01755	COG3166	PFAM Fimbrial assembly family protein
HS089_RS01770	COG4796	Type ii and iii secretion system protein
HS089_RS01785	COG3266	domain, Protein
HS089_RS01790	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HS089_RS01795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HS089_RS01805	COG0180	Tryptophanyl-tRNA synthetase
HS089_RS01810	COG2188	Transcriptional regulator
HS089_RS01820	COG3457	Alanine racemase
HS089_RS01825	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HS089_RS01830	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HS089_RS01845	COG0626	cystathionine gamma-synthase activity
HS089_RS01865	COG2146	nitrite reductase [NAD(P)H] activity
HS089_RS01870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HS089_RS01895	COG0512	Glutamine amidotransferase of anthranilate synthase
HS089_RS01900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HS089_RS01905	COG1289	transmembrane transporter activity
HS089_RS01915	COG1765	OsmC-like protein
HS089_RS01920	COG3954	Phosphoribulokinase
HS089_RS01930	COG0429	hydrolase of the alpha beta-hydrolase fold
HS089_RS01940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HS089_RS01950	COG0488	(ABC) transporter
HS089_RS01965	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HS089_RS01970	COG1047	Peptidyl-prolyl cis-trans
HS089_RS01980	COG0545	Peptidyl-prolyl cis-trans isomerase
HS089_RS01985	COG2964	Protein conserved in bacteria
HS089_RS02010	COG0049	tRNA binding
HS089_RS02040	COG0051	transcription antitermination factor activity, RNA binding
HS089_RS02050	COG0088	Forms part of the polypeptide exit tunnel
HS089_RS02065	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HS089_RS02140	COG0200	Binds to the 23S rRNA
HS089_RS02145	COG0201	protein transport
HS089_RS02160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HS089_RS02185	COG0789	Transcriptional regulator
HS089_RS02190	COG3036	rescue of stalled ribosome
HS089_RS02200	COG0569	domain protein
HS089_RS02220	COG0758	DNA mediated transformation
HS089_RS02230	COG0551	DNA topoisomerase type I activity
HS089_RS02250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HS089_RS02290	COG1126	abc transporter atp-binding protein
HS089_RS02295	COG0765	amino acid transport
HS089_RS02300	COG4597	amino acid ABC transporter
HS089_RS02305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS089_RS02315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HS089_RS02320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS089_RS02325	COG1309	transcriptional regulator
HS089_RS02335	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HS089_RS02415	COG4145	pantothenate transmembrane transporter activity
HS089_RS02420	COG3924	membrane
HS089_RS02425	COG0439	Biotin carboxylase
HS089_RS02430	COG0511	ligase activity, forming carbon-carbon bonds
HS089_RS02445	COG0604	alcohol dehydrogenase
HS089_RS02450	COG2200	EAL domain
HS089_RS02450	COG2199	diguanylate cyclase activity
HS089_RS02460	COG1077	Cell shape determining protein MreB Mrl
HS089_RS02465	COG1792	Involved in formation and maintenance of cell shape
HS089_RS02470	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HS089_RS02485	COG3164	Protein of unknown function
HS089_RS02490	COG0312	modulator of DNA gyrase
HS089_RS02495	COG0583	DNA-binding transcription factor activity
HS089_RS02515	COG2732	(Barnase) inhibitor
HS089_RS02535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HS089_RS02540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HS089_RS02545	COG3105	Protein conserved in bacteria
HS089_RS02550	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HS089_RS02565	COG0625	glutathione transferase activity
HS089_RS02570	COG2969	positive regulation of protein catabolic process
HS089_RS02575	COG3069	C4-dicarboxylate transmembrane transporter activity
HS089_RS02600	COG2731	YhcH YjgK YiaL family protein
HS089_RS02605	COG0402	S-adenosylhomocysteine deaminase activity
HS089_RS02610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HS089_RS02615	COG4804	nuclease activity
HS089_RS02620	COG0493	'glutamate synthase
HS089_RS02625	COG0067	glutamate synthase
HS089_RS02625	COG0069	glutamate synthase activity
HS089_RS02625	COG0070	glutamate synthase
HS089_RS02630	COG1242	4 iron, 4 sulfur cluster binding
HS089_RS02635	COG2198	Histidine kinase
HS089_RS02635	COG0784	Response regulator, receiver
HS089_RS02635	COG5002	protein histidine kinase activity
HS089_RS02640	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HS089_RS02650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS089_RS02665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HS089_RS02675	COG1137	ATPase activity
HS089_RS02680	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HS089_RS02685	COG3117	lipopolysaccharide transmembrane transporter activity
HS089_RS02690	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HS089_RS02700	COG0530	calcium, potassium:sodium antiporter activity
HS089_RS02705	COG1127	ABC transporter
HS089_RS02710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HS089_RS02715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HS089_RS02720	COG2854	intermembrane phospholipid transfer
HS089_RS02725	COG3113	response to antibiotic
HS089_RS02730	COG5007	Belongs to the BolA IbaG family
HS089_RS02740	COG3423	Transcriptional regulator
HS089_RS02745	COG0142	geranyltranstransferase activity
HS089_RS02750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HS089_RS02755	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HS089_RS02760	COG0697	spore germination
HS089_RS02770	COG2027	D-alanyl-D-alanine carboxypeptidase
HS089_RS02780	COG1534	Rna-binding protein
HS089_RS02790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HS089_RS02795	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HS089_RS02805	COG3069	C4-dicarboxylate transmembrane transporter activity
HS089_RS02810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HS089_RS02815	COG0583	DNA-binding transcription factor activity
HS089_RS02820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HS089_RS02845	COG0195	Participates in both transcription termination and antitermination
HS089_RS02850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HS089_RS02855	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HS089_RS02885	COG0513	Belongs to the DEAD box helicase family
HS089_RS02890	COG0814	amino acid
HS089_RS02895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HS089_RS02900	COG0826	peptidase U32
HS089_RS02905	COG0826	peptidase U32
HS089_RS02910	COG3154	lipid carrier protein
HS089_RS02915	COG3153	acetyltransferase
HS089_RS02930	COG0702	epimerase
HS089_RS02935	COG2823	Periplasmic or secreted lipoprotein
HS089_RS02955	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HS089_RS02965	COG2222	sugar isomerase
HS089_RS02970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HS089_RS02975	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS089_RS02980	COG3716	PTS system mannose fructose sorbose family IID component
HS089_RS02990	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS089_RS03000	COG1349	DNA-binding transcription factor activity
HS089_RS03005	COG1349	DNA-binding transcription factor activity
HS089_RS03010	COG1940	carbohydrate kinase activity
HS089_RS03015	COG0673	inositol 2-dehydrogenase activity
HS089_RS03020	COG3842	ATPase activity
HS089_RS03025	COG0395	ABC-type sugar transport system, permease component
HS089_RS03030	COG1175	transmembrane transport
HS089_RS03040	COG2721	sulfolactate sulfo-lyase activity
HS089_RS03045	COG2271	Major facilitator Superfamily
HS089_RS03055	COG2084	Dehydrogenase
HS089_RS03060	COG1929	Belongs to the glycerate kinase type-1 family
HS089_RS03100	COG0583	DNA-binding transcription factor activity
HS089_RS03120	COG1882	Formate acetyltransferase
HS089_RS03125	COG0251	oxidation-reduction process
HS089_RS03130	COG1760	l-serine dehydratase
HS089_RS03135	COG0814	amino acid
HS089_RS03150	COG1741	Belongs to the pirin family
HS089_RS03155	COG0583	DNA-binding transcription factor activity
HS089_RS03160	COG3152	Membrane
HS089_RS03165	COG0435	Glutathione S-transferase
HS089_RS03170	COG2259	Doxx family
HS089_RS03180	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HS089_RS03185	COG4575	ribosome binding
HS089_RS03190	COG1422	Protein of unknown function (DUF1090)
HS089_RS03200	COG0586	Pfam SNARE associated Golgi protein
HS089_RS03205	COG2186	Transcriptional regulator
HS089_RS03210	COG2271	Major facilitator Superfamily
HS089_RS03220	COG2721	sulfolactate sulfo-lyase activity
HS089_RS03240	COG0673	inositol 2-dehydrogenase activity
HS089_RS03245	COG1451	nucleotide metabolic process
HS089_RS03255	COG0446	pyridine nucleotide-disulphide oxidoreductase
HS089_RS03255	COG1902	pentaerythritol trinitrate reductase activity
HS089_RS03260	COG3408	Glycogen debranching enzyme
HS089_RS03260	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HS089_RS03270	COG0531	amino acid
HS089_RS03275	COG2731	YhcH YjgK YiaL family protein
HS089_RS03280	COG3250	beta-galactosidase activity
HS089_RS03285	COG1609	Transcriptional regulator
HS089_RS03290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HS089_RS03300	COG0840	transmembrane signaling receptor activity
HS089_RS03305	COG1695	Transcriptional regulator
HS089_RS03310	COG2375	cellular response to nickel ion
HS089_RS03320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HS089_RS03385	COG0582	viral genome integration into host DNA
HS089_RS03440	COG0740	serine-type endopeptidase activity
HS089_RS03475	COG4771	TonB-dependent receptor
HS089_RS03480	COG3391	amine dehydrogenase activity
HS089_RS03490	COG0358	DNA primase activity
HS089_RS03495	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HS089_RS03500	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HS089_RS03505	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HS089_RS03515	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HS089_RS03545	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HS089_RS03550	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HS089_RS03565	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HS089_RS03580	COG4991	sh3 domain protein
HS089_RS03585	COG3025	triphosphatase activity
HS089_RS03600	COG2268	Band 7 protein
HS089_RS03605	COG1585	Membrane protein implicated in regulation of membrane protease activity
HS089_RS03645	COG3384	dioxygenase
HS089_RS03650	COG0754	glutathionylspermidine amidase activity
HS089_RS03665	COG0494	nUDIX hydrolase
HS089_RS03670	COG3151	Protein conserved in bacteria
HS089_RS03675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HS089_RS03680	COG3150	esterase
HS089_RS03685	COG0187	DNA topoisomerase II activity
HS089_RS03690	COG4977	sequence-specific DNA binding
HS089_RS03690	COG1917	Cupin 2, conserved barrel domain protein
HS089_RS03700	COG2211	Major facilitator Superfamily
HS089_RS03705	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HS089_RS03710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HS089_RS03715	COG2249	NAD(P)H dehydrogenase (quinone) activity
HS089_RS03730	COG3111	PFAM Bacterial OB fold (BOF) protein
HS089_RS03750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HS089_RS03765	COG0471	metal ion transport
HS089_RS03770	COG0656	L-ascorbic acid biosynthetic process
HS089_RS03775	COG1979	alcohol dehydrogenase
HS089_RS03780	COG2207	Transcriptional regulator
HS089_RS03785	COG0586	Pfam SNARE associated Golgi protein
HS089_RS03790	COG0626	cystathionine gamma-synthase activity
HS089_RS03800	COG0848	biopolymer transport protein
HS089_RS03820	COG0667	Aldo Keto reductase
HS089_RS03830	COG0840	transmembrane signaling receptor activity
HS089_RS03840	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HS089_RS03845	COG0437	4 iron, 4 sulfur cluster binding
HS089_RS03850	COG5557	Pfam Polysulphide reductase, NrfD
HS089_RS03855	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HS089_RS03860	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HS089_RS03865	COG1773	rubredoxin
HS089_RS03875	COG0298	carbon dioxide binding
HS089_RS03880	COG0625	glutathione transferase activity
HS089_RS03885	COG0243	molybdopterin cofactor binding
HS089_RS03890	COG0754	glutathionylspermidine amidase activity
HS089_RS03900	COG1811	Na channel or pump
HS089_RS03905	COG1982	Orn Lys Arg decarboxylase major
HS089_RS03910	COG2211	Major facilitator Superfamily
HS089_RS03925	COG1194	a g-specific adenine glycosylase
HS089_RS03935	COG3171	Protein conserved in bacteria
HS089_RS03945	COG0252	asparaginase activity
HS089_RS03950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HS089_RS03965	COG0762	integral membrane protein
HS089_RS03970	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HS089_RS03975	COG2805	Type II/IV secretion system protein
HS089_RS03990	COG0189	ligase activity
HS089_RS03995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HS089_RS04000	COG2356	endonuclease I
HS089_RS04005	COG3091	SprT-like family
HS089_RS04010	COG2814	Major facilitator Superfamily
HS089_RS04030	COG1166	arginine decarboxylase activity
HS089_RS04040	COG0501	Belongs to the peptidase M48B family
HS089_RS04045	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HS089_RS04050	COG1122	ATPase activity
HS089_RS04055	COG1122	ATPase activity
HS089_RS04085	COG0191	fructose-bisphosphate aldolase activity
HS089_RS04090	COG0668	transmembrane transport
HS089_RS04095	COG1279	arginine transmembrane transporter activity
HS089_RS04100	COG2968	Membrane
HS089_RS04105	COG0583	DNA-binding transcription factor activity
HS089_RS04110	COG0427	acetyl-CoA hydrolase
HS089_RS04115	COG1024	Enoyl-CoA hydratase
HS089_RS04120	COG1703	isobutyryl-CoA mutase activity
HS089_RS04125	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HS089_RS04125	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HS089_RS04140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HS089_RS04145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HS089_RS04165	COG0006	proline dipeptidase activity
HS089_RS04170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HS089_RS04175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HS089_RS04195	COG1028	Short-chain dehydrogenase reductase Sdr
HS089_RS04200	COG2723	6-phospho-beta-galactosidase activity
HS089_RS04205	COG1737	Transcriptional regulator
HS089_RS04215	COG1272	protein, Hemolysin III
HS089_RS04225	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HS089_RS04250	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HS089_RS04270	COG4942	peptidase
HS089_RS04380	COG0457	Tetratricopeptide repeat
HS089_RS04385	COG1649	PFAM Uncharacterised BCR, COG1649
HS089_RS04385	COG0726	polysaccharide deacetylase
HS089_RS04390	COG1215	transferase activity, transferring glycosyl groups
HS089_RS04400	COG3592	Divergent 4Fe-4S mono-cluster
HS089_RS04405	COG2388	GCN5-related N-acetyl-transferase
HS089_RS04410	COG0583	DNA-binding transcription factor activity
HS089_RS04415	COG0666	response to abiotic stimulus
HS089_RS04425	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HS089_RS04430	COG1304	FMN binding
HS089_RS04440	COG0549	Belongs to the carbamate kinase family
HS089_RS04445	COG0402	S-adenosylhomocysteine deaminase activity
HS089_RS04460	COG0814	amino acid
HS089_RS04475	COG0183	Belongs to the thiolase family
HS089_RS04485	COG1028	Short-chain dehydrogenase reductase Sdr
HS089_RS04490	COG2814	Major facilitator Superfamily
HS089_RS04495	COG5464	transposase or invertase
HS089_RS04505	COG1794	racemase activity, acting on amino acids and derivatives
HS089_RS04510	COG0583	DNA-binding transcription factor activity
HS089_RS04520	COG1609	Transcriptional regulator
HS089_RS04540	COG0667	Aldo Keto reductase
HS089_RS04550	COG0861	Integral membrane protein TerC family
HS089_RS04580	COG2165	general secretion pathway protein
HS089_RS04585	COG4795	General secretion pathway protein
HS089_RS04595	COG4967	type IV pilus modification protein PilV
HS089_RS04600	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HS089_RS04610	COG1074	ATP-dependent DNA helicase activity
HS089_RS04615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HS089_RS04620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HS089_RS04620	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HS089_RS04625	COG0860	N-Acetylmuramoyl-L-alanine amidase
HS089_RS04650	COG3121	Chaperone
HS089_RS04655	COG3188	usher protein
HS089_RS04700	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HS089_RS04705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HS089_RS04710	COG2166	iron-sulfur cluster assembly
HS089_RS04715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HS089_RS04725	COG0583	DNA-binding transcription factor activity
HS089_RS04730	COG2363	Small membrane protein
HS089_RS04740	COG1349	DNA-binding transcription factor activity
HS089_RS04750	COG1070	Carbohydrate kinase
HS089_RS04760	COG1129	ABC transporter
HS089_RS04765	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS089_RS04775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HS089_RS04785	COG0235	Class ii aldolase
HS089_RS04790	COG1454	alcohol dehydrogenase
HS089_RS04800	COG1760	l-serine dehydratase
HS089_RS04805	COG0814	amino acid
HS089_RS04810	COG1611	Belongs to the LOG family
HS089_RS04825	COG3098	single-species biofilm formation
HS089_RS04830	COG0564	pseudouridine synthase activity
HS089_RS04835	COG0716	FMN binding
HS089_RS04840	COG2271	Major facilitator Superfamily
HS089_RS04845	COG4948	Mandelate Racemase Muconate Lactonizing
HS089_RS04850	COG4948	Mandelate Racemase Muconate Lactonizing
HS089_RS04855	COG1929	Belongs to the glycerate kinase type-1 family
HS089_RS04860	COG3437	response regulator, receiver
HS089_RS04860	COG2205	protein histidine kinase activity
HS089_RS04860	COG4999	Histidine kinase
HS089_RS04860	COG3850	Histidine kinase
HS089_RS04870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HS089_RS04875	COG3956	TIGRFAM MazG family protein
HS089_RS04890	COG1737	Transcriptional regulator
HS089_RS04895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS089_RS04895	COG2190	(PTS) system
HS089_RS04895	COG1263	PTS System
HS089_RS04900	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HS089_RS04905	COG0602	queuosine metabolic process
HS089_RS04910	COG0720	synthase
HS089_RS04930	COG2234	aminopeptidase activity
HS089_RS04985	COG4942	peptidase
HS089_RS04985	COG1388	LysM domain
HS089_RS05000	COG0163	prenyltransferase activity
HS089_RS05005	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HS089_RS05030	COG0628	permease
HS089_RS05035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HS089_RS05055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HS089_RS05060	COG1882	Formate acetyltransferase
HS089_RS05075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HS089_RS05080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HS089_RS05085	COG1121	(ABC) transporter
HS089_RS05105	COG0309	Hydrogenase expression formation protein (HypE)
HS089_RS05110	COG0409	Hydrogenase expression formation protein
HS089_RS05115	COG0298	carbon dioxide binding
HS089_RS05120	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HS089_RS05125	COG0375	protein maturation
HS089_RS05135	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS089_RS05140	COG0651	ATP synthesis coupled electron transport
HS089_RS05145	COG0650	Formate hydrogenlyase subunit 4
HS089_RS05150	COG3261	NADH dehydrogenase
HS089_RS05150	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HS089_RS05155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HS089_RS05160	COG3260	NADH ubiquinone oxidoreductase 20
HS089_RS05170	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HS089_RS05180	COG2723	6-phospho-beta-galactosidase activity
HS089_RS05190	COG1609	Transcriptional regulator
HS089_RS05195	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS089_RS05200	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HS089_RS05220	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HS089_RS05220	COG0517	IMP dehydrogenase activity
HS089_RS05225	COG1349	DNA-binding transcription factor activity
HS089_RS05230	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS089_RS05235	COG1028	Short-chain dehydrogenase reductase Sdr
HS089_RS05245	COG3732	PTS system glucitol sorbitol-specific
HS089_RS05250	COG3730	PTS system glucitol sorbitol-specific
HS089_RS05255	COG2951	lytic endotransglycosylase activity
HS089_RS05260	COG1546	Belongs to the CinA family
HS089_RS05280	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HS089_RS05310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HS089_RS05315	COG1238	metal cluster binding
HS089_RS05335	COG2814	Major facilitator Superfamily
HS089_RS05340	COG1566	PFAM secretion protein HlyD family protein
HS089_RS05345	COG1846	Transcriptional regulator
HS089_RS05355	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HS089_RS05360	COG2814	Major facilitator Superfamily
HS089_RS05370	COG4176	ABC-type proline glycine betaine transport system permease component
HS089_RS05400	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HS089_RS05430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HS089_RS05435	COG0640	Transcriptional regulator
HS089_RS05440	COG0401	homolog of Blt101
HS089_RS05445	COG1652	LysM domain
HS089_RS05450	COG1802	Transcriptional regulator
HS089_RS05455	COG1113	amino acid transport
HS089_RS05460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HS089_RS05465	COG1012	belongs to the aldehyde dehydrogenase family
HS089_RS05470	COG0579	oxidoreductase
HS089_RS05480	COG1285	pathogenesis
HS089_RS05485	COG2211	Major facilitator Superfamily
HS089_RS05540	COG3188	usher protein
HS089_RS05545	COG3121	Chaperone
HS089_RS05590	COG0438	transferase activity, transferring glycosyl groups
HS089_RS05595	COG0297	glycogen (starch) synthase activity
HS089_RS05595	COG0438	transferase activity, transferring glycosyl groups
HS089_RS05630	COG3829	transcription factor binding
HS089_RS05635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HS089_RS05640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HS089_RS05645	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HS089_RS05650	COG2271	Major facilitator Superfamily
HS089_RS05655	COG2197	response regulator
HS089_RS05660	COG2198	Histidine kinase
HS089_RS05660	COG2205	protein histidine kinase activity
HS089_RS05660	COG0784	Response regulator, receiver
HS089_RS05660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS089_RS05680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HS089_RS05685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS089_RS05690	COG3065	identical protein binding
HS089_RS05705	COG3962	Belongs to the TPP enzyme family
HS089_RS05710	COG0673	inositol 2-dehydrogenase activity
HS089_RS05725	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS089_RS05735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS089_RS05745	COG3718	enzyme involved in inositol metabolism
HS089_RS05755	COG1388	LysM domain
HS089_RS05755	COG1470	cell adhesion involved in biofilm formation
HS089_RS05830	COG0582	viral genome integration into host DNA
HS089_RS05840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS089_RS05865	COG2867	negative regulation of translational initiation
HS089_RS05880	COG0497	DNA recombination
HS089_RS05895	COG4536	flavin adenine dinucleotide binding
HS089_RS05900	COG4137	Cytochrome C assembly protein
HS089_RS05905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HS089_RS05930	COG2885	chlorophyll binding
HS089_RS05935	COG2199	diguanylate cyclase activity
HS089_RS05950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HS089_RS05955	COG1605	Chorismate mutase
HS089_RS05955	COG0287	Prephenate dehydrogenase
HS089_RS05960	COG0077	Prephenate dehydratase
HS089_RS05960	COG1605	Chorismate mutase
HS089_RS05970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HS089_RS05975	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HS089_RS05990	COG0542	response to heat
HS089_RS06015	COG0477	Major facilitator Superfamily
HS089_RS06020	COG5544	Lipoprotein
HS089_RS06025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HS089_RS06035	COG3148	PFAM DTW domain containing protein
HS089_RS06040	COG3118	belongs to the thioredoxin family
HS089_RS06045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HS089_RS06070	COG0513	Belongs to the DEAD box helicase family
HS089_RS06080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HS089_RS06090	COG1595	DNA-templated transcription, initiation
HS089_RS06095	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HS089_RS06100	COG3026	antisigma factor binding
HS089_RS06105	COG3086	response to oxidative stress
HS089_RS06115	COG0681	Belongs to the peptidase S26 family
HS089_RS06135	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HS089_RS06145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS089_RS06150	COG1737	Transcriptional regulator
HS089_RS06155	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HS089_RS06160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS089_RS06160	COG1263	PTS System
HS089_RS06165	COG0560	Phosphoserine phosphatase
HS089_RS06185	COG2205	protein histidine kinase activity
HS089_RS06190	COG3170	Tfp pilus assembly protein FimV
HS089_RS06195	COG2204	response regulator
HS089_RS06200	COG0347	Belongs to the P(II) protein family
HS089_RS06205	COG1017	nitric oxide dioxygenase activity
HS089_RS06205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HS089_RS06235	COG4638	Rieske (2fe-2S)
HS089_RS06240	COG0583	DNA-binding transcription factor activity
HS089_RS06245	COG1940	carbohydrate kinase activity
HS089_RS06250	COG0457	Tetratricopeptide repeat
HS089_RS06255	COG2814	Major facilitator Superfamily
HS089_RS06255	COG0477	Major facilitator Superfamily
HS089_RS06265	COG2814	Major facilitator Superfamily
HS089_RS06270	COG3711	transcriptional antiterminator
HS089_RS06275	COG0517	IMP dehydrogenase activity
HS089_RS06275	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HS089_RS06280	COG1069	ribulokinase activity
HS089_RS06290	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS089_RS06295	COG1129	ABC transporter
HS089_RS06305	COG3683	transport system, periplasmic component
HS089_RS06310	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HS089_RS06330	COG1104	cysteine desulfurase activity
HS089_RS06335	COG0822	iron-sulfur transferase activity
HS089_RS06355	COG0633	Ferredoxin
HS089_RS06360	COG2975	iron-sulfur cluster assembly
HS089_RS06375	COG2897	thiosulfate sulfurtransferase activity
HS089_RS06380	COG2373	Large extracellular alpha-helical protein
HS089_RS06385	COG4953	penicillin-binding protein 1C
HS089_RS06400	COG1426	Protein conserved in bacteria
HS089_RS06415	COG2976	Protein conserved in bacteria
HS089_RS06440	COG1645	bacterial-type flagellum-dependent swarming motility
HS089_RS06465	COG0516	GMP reductase activity
HS089_RS06465	COG0517	IMP dehydrogenase activity
HS089_RS06490	COG0668	transmembrane transport
HS089_RS06500	COG2200	EAL domain
HS089_RS06505	COG0248	Ppx GppA phosphatase
HS089_RS06515	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HS089_RS06525	COG2723	6-phospho-beta-galactosidase activity
HS089_RS06535	COG2233	PERMEase
HS089_RS06545	COG1393	Belongs to the ArsC family
HS089_RS06550	COG4783	chaperone-mediated protein folding
HS089_RS06555	COG0628	permease
HS089_RS06560	COG3366	ferrous iron transmembrane transporter activity
HS089_RS06565	COG0700	Nucleoside recognition
HS089_RS06570	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HS089_RS06575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HS089_RS06580	COG2716	regulation of RNA biosynthetic process
HS089_RS06590	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HS089_RS06600	COG2321	neutral zinc metallopeptidase
HS089_RS06610	COG0400	carboxylic ester hydrolase activity
HS089_RS06625	COG1393	Belongs to the ArsC family
HS089_RS06635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HS089_RS06640	COG3850	Histidine kinase
HS089_RS06645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS089_RS06645	COG0493	'glutamate synthase
HS089_RS06655	COG5342	invasion associated locus B
HS089_RS06660	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HS089_RS06680	COG4766	ethanolamine catabolic process
HS089_RS06685	COG4812	Cobalamin adenosyltransferase
HS089_RS06745	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HS089_RS06750	COG2207	Transcriptional regulator
HS089_RS06760	COG0860	N-Acetylmuramoyl-L-alanine amidase
HS089_RS06780	COG2837	iron assimilation
HS089_RS06795	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HS089_RS06800	COG4208	sulfate ABC transporter
HS089_RS06805	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HS089_RS06870	COG3530	Putative quorum-sensing-regulated virulence factor
HS089_RS06875	COG0385	Bile acid
HS089_RS06880	COG0583	DNA-binding transcription factor activity
HS089_RS06890	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HS089_RS06895	COG2211	Major facilitator Superfamily
HS089_RS06905	COG0583	DNA-binding transcription factor activity
HS089_RS06940	COG3415	Transposase
HS089_RS06945	COG3415	Transposase
HS089_RS06960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HS089_RS06975	COG0667	Aldo Keto reductase
HS089_RS06980	COG3961	Belongs to the TPP enzyme family
HS089_RS06995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS07000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS07005	COG0006	proline dipeptidase activity
HS089_RS07010	COG1363	Peptidase, m42
HS089_RS07030	COG2207	Transcriptional regulator
HS089_RS07035	COG3279	Response regulator of the LytR AlgR family
HS089_RS07040	COG3275	phosphorelay sensor kinase activity
HS089_RS07045	COG0436	Aminotransferase
HS089_RS07060	COG1560	Kdo2-lipid A biosynthetic process
HS089_RS07090	COG3122	Protein conserved in bacteria
HS089_RS07095	COG0840	transmembrane signaling receptor activity
HS089_RS07110	COG2116	formate transmembrane transporter activity
HS089_RS07120	COG2067	long-chain fatty acid transport protein
HS089_RS07125	COG3691	Protein conserved in bacteria
HS089_RS07140	COG2062	phosphohistidine phosphatase, SixA
HS089_RS07165	COG0730	response to heat
HS089_RS07170	COG3101	peptidyl-lysine hydroxylation
HS089_RS07185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HS089_RS07205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HS089_RS07215	COG0586	Pfam SNARE associated Golgi protein
HS089_RS07225	COG0285	dihydrofolate synthase activity
HS089_RS07230	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HS089_RS07235	COG1286	toxin biosynthetic process
HS089_RS07240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HS089_RS07245	COG0163	prenyltransferase activity
HS089_RS07255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS089_RS07260	COG4215	(ABC) transporter
HS089_RS07270	COG4598	ABC transporter
HS089_RS07275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HS089_RS07280	COG1090	epimerase
HS089_RS07285	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HS089_RS07290	COG0625	glutathione transferase activity
HS089_RS07295	COG0625	glutathione transferase activity
HS089_RS07300	COG0622	Phosphoesterase
HS089_RS07310	COG1288	antiporter activity
HS089_RS07335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HS089_RS07340	COG0471	metal ion transport
HS089_RS07340	COG0490	domain, Protein
HS089_RS07350	COG0436	Aminotransferase
HS089_RS07355	COG0583	DNA-binding transcription factor activity
HS089_RS07375	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HS089_RS07400	COG0839	Belongs to the complex I subunit 6 family
HS089_RS07410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HS089_RS07415	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HS089_RS07425	COG0835	chemotaxis
HS089_RS07425	COG0784	Response regulator, receiver
HS089_RS07435	COG2153	protein acetylation
HS089_RS07440	COG4575	ribosome binding
HS089_RS07445	COG1169	isochorismate synthase
HS089_RS07535	COG0247	lactate metabolic process
HS089_RS07545	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HS089_RS07550	COG2271	Major facilitator Superfamily
HS089_RS07555	COG0584	glycerophosphoryl diester phosphodiesterase
HS089_RS07560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HS089_RS07595	COG2198	Histidine kinase
HS089_RS07595	COG0642	Histidine kinase
HS089_RS07600	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HS089_RS07605	COG1477	protein flavinylation
HS089_RS07610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HS089_RS07610	COG2169	Transcriptional regulator
HS089_RS07615	COG3145	DNA-N1-methyladenine dioxygenase activity
HS089_RS07620	COG4615	Cyclic peptide transporter
HS089_RS07625	COG2239	Acts as a magnesium transporter
HS089_RS07630	COG0659	secondary active sulfate transmembrane transporter activity
HS089_RS07645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS089_RS07645	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS089_RS07650	COG3062	negative regulation of establishment of protein localization
HS089_RS07660	COG0437	4 iron, 4 sulfur cluster binding
HS089_RS07665	COG0348	domain, Protein
HS089_RS07670	COG3043	anaerobic respiration
HS089_RS07675	COG3005	denitrification pathway
HS089_RS07680	COG4133	protoheme IX ABC transporter activity
HS089_RS07690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HS089_RS07695	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HS089_RS07705	COG1138	Cytochrome C-type biogenesis protein
HS089_RS07710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HS089_RS07715	COG3088	subunit of a heme lyase
HS089_RS07715	COG4235	cytochrome complex assembly
HS089_RS07720	COG2197	response regulator
HS089_RS07775	COG1061	Type III restriction enzyme res subunit
HS089_RS07780	COG1187	pseudouridine synthase activity
HS089_RS07785	COG2814	Major facilitator Superfamily
HS089_RS07795	COG4172	Belongs to the ABC transporter superfamily
HS089_RS07800	COG4239	(ABC) transporter, permease
HS089_RS07805	COG4174	ABC transporter (Permease)
HS089_RS07810	COG4166	transmembrane transport
HS089_RS07815	COG2200	EAL domain
HS089_RS07820	COG0791	NLP P60 protein
HS089_RS07825	COG0671	phosphoesterase, PA-phosphatase related
HS089_RS07830	COG0523	cobalamin synthesis protein
HS089_RS07835	COG0246	Mannitol dehydrogenase
HS089_RS07840	COG1312	Catalyzes the dehydration of D-mannonate
HS089_RS07845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HS089_RS07850	COG3005	denitrification pathway
HS089_RS07860	COG3381	protein complex oligomerization
HS089_RS07890	COG4372	Transposase
HS089_RS07895	COG3436	PFAM IS66 Orf2 family protein
HS089_RS07950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HS089_RS07970	COG1105	Belongs to the carbohydrate kinase PfkB family
HS089_RS07975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS07975	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HS089_RS07975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS07980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HS089_RS07990	COG0583	DNA-binding transcription factor activity
HS089_RS07995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS089_RS08000	COG2313	pseudouridylate synthase activity
HS089_RS08005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HS089_RS08010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS089_RS08010	COG1522	sequence-specific DNA binding
HS089_RS08020	COG2855	membrane
HS089_RS08025	COG0583	DNA-binding transcription factor activity
HS089_RS08030	COG0833	amino acid
HS089_RS08035	COG4771	TonB-dependent receptor
HS089_RS08040	COG2271	Major facilitator Superfamily
HS089_RS08045	COG0560	Phosphoserine phosphatase
HS089_RS08050	COG1760	l-serine dehydratase
HS089_RS08070	COG2311	Membrane
HS089_RS08085	COG1129	ABC transporter
HS089_RS08100	COG0493	'glutamate synthase
HS089_RS08110	COG2949	membrane
HS089_RS08120	COG1346	cytolysis
HS089_RS08135	COG2271	Major facilitator Superfamily
HS089_RS08150	COG0625	glutathione transferase activity
HS089_RS08155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HS089_RS08160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HS089_RS08175	COG0586	Pfam SNARE associated Golgi protein
HS089_RS08185	COG1686	Belongs to the peptidase S11 family
HS089_RS08190	COG0277	FAD linked oxidase domain protein
HS089_RS08195	COG1472	Belongs to the glycosyl hydrolase 3 family
HS089_RS08200	COG1732	Glycine betaine
HS089_RS08205	COG1174	glycine betaine transport
HS089_RS08210	COG1125	glycine betaine transport
HS089_RS08215	COG1174	glycine betaine transport
HS089_RS08225	COG0789	Transcriptional regulator
HS089_RS08230	COG3275	phosphorelay sensor kinase activity
HS089_RS08240	COG4807	Protein conserved in bacteria
HS089_RS08245	COG4808	Protein conserved in bacteria
HS089_RS08255	COG0489	protein tyrosine kinase activity
HS089_RS08270	COG3121	Chaperone
HS089_RS08275	COG3188	usher protein
HS089_RS08285	COG5455	response to cobalt ion
HS089_RS08310	COG0582	viral genome integration into host DNA
HS089_RS08390	COG0351	phosphomethylpyrimidine kinase
HS089_RS08395	COG2188	Transcriptional regulator
HS089_RS08400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS089_RS08405	COG1397	ADP-ribosylglycohydrolase
HS089_RS08410	COG2211	Major facilitator Superfamily
HS089_RS08415	COG1830	Aldolase
HS089_RS08425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS089_RS08430	COG4160	amino acid transport
HS089_RS08435	COG4215	(ABC) transporter
HS089_RS08440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS089_RS08445	COG1126	abc transporter atp-binding protein
HS089_RS08460	COG3023	N-Acetylmuramoyl-L-alanine amidase
HS089_RS08465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HS089_RS08470	COG0702	epimerase
HS089_RS08475	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HS089_RS08480	COG0028	Belongs to the TPP enzyme family
HS089_RS08490	COG4529	Protein conserved in bacteria
HS089_RS08495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HS089_RS08505	COG2431	L-lysine efflux transmembrane transporter activity
HS089_RS08515	COG3593	DNA synthesis involved in DNA repair
HS089_RS08520	COG2990	Protein conserved in bacteria
HS089_RS08525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS089_RS08535	COG1278	Cold shock
HS089_RS08545	COG0542	response to heat
HS089_RS08550	COG0826	peptidase U32
HS089_RS08560	COG0745	RESPONSE REGULATOR receiver
HS089_RS08565	COG2205	protein histidine kinase activity
HS089_RS08595	COG0443	Heat shock 70 kDa protein
HS089_RS08600	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HS089_RS08605	COG5001	Diguanylate cyclase
HS089_RS08605	COG5002	protein histidine kinase activity
HS089_RS08605	COG3447	MASE1 domain protein
HS089_RS08620	COG2982	Protein involved in outer membrane biogenesis
HS089_RS08625	COG1253	flavin adenine dinucleotide binding
HS089_RS08645	COG0463	Glycosyl transferase, family 2
HS089_RS08650	COG1045	serine acetyltransferase
HS089_RS08655	COG0438	transferase activity, transferring glycosyl groups
HS089_RS08665	COG1216	Glycosyl transferase, family 2
HS089_RS08670	COG0110	maltose O-acetyltransferase activity
HS089_RS08675	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HS089_RS08680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HS089_RS08685	COG1051	belongs to the nudix hydrolase family
HS089_RS08690	COG0297	glycogen (starch) synthase activity
HS089_RS08700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HS089_RS08705	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HS089_RS08710	COG2244	polysaccharide biosynthetic process
HS089_RS08715	COG2327	Polysaccharide pyruvyl transferase
HS089_RS08745	COG1215	transferase activity, transferring glycosyl groups
HS089_RS08750	COG0438	transferase activity, transferring glycosyl groups
HS089_RS08785	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HS089_RS08800	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HS089_RS08805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HS089_RS08805	COG0140	phosphoribosyl-ATP diphosphatase activity
HS089_RS08820	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HS089_RS08850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HS089_RS08855	COG0583	DNA-binding transcription factor activity
HS089_RS08865	COG0531	amino acid
HS089_RS08870	COG2925	Exonuclease
HS089_RS08905	COG1289	transmembrane transporter activity
HS089_RS08940	COG4656	Part of a membrane complex involved in electron transport
HS089_RS08950	COG1012	belongs to the aldehyde dehydrogenase family
HS089_RS08960	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HS089_RS09130	COG1376	ErfK ybiS ycfS ynhG family protein
HS089_RS09135	COG3842	ATPase activity
HS089_RS09140	COG1178	ABC-type Fe3 transport system permease component
HS089_RS09145	COG1840	ABC-type Fe3 transport system, periplasmic component
HS089_RS09165	COG2076	Multidrug Resistance protein
HS089_RS09170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HS089_RS09175	COG1418	mRNA catabolic process
HS089_RS09180	COG0270	DNA (cytosine-5-)-methyltransferase activity
HS089_RS09185	COG3727	T/G mismatch-specific endonuclease activity
HS089_RS09190	COG0697	spore germination
HS089_RS09195	COG2354	Protein conserved in bacteria
HS089_RS09200	COG5475	Uncharacterized small protein (DUF2158)
HS089_RS09260	COG2882	bacterial-type flagellum organization
HS089_RS09265	COG1157	protein secretion by the type III secretion system
HS089_RS09290	COG0425	Belongs to the sulfur carrier protein TusA family
HS089_RS09305	COG0366	Alpha amylase catalytic
HS089_RS09340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS089_RS09350	COG0765	amino acid transport
HS089_RS09355	COG1126	abc transporter atp-binding protein
HS089_RS09360	COG2197	response regulator
HS089_RS09370	COG2197	response regulator
HS089_RS09415	COG1305	Transglutaminase-like
HS089_RS09425	COG2608	mercury ion transmembrane transporter activity
HS089_RS09430	COG3012	SEC-C Motif Domain Protein
HS089_RS09430	COG3318	Belongs to the UPF0149 family
HS089_RS09435	COG0814	amino acid
HS089_RS09445	COG1528	Iron-storage protein
HS089_RS09460	COG0477	Major facilitator Superfamily
HS089_RS09470	COG1528	Iron-storage protein
HS089_RS09480	COG1879	ABC-type sugar transport system periplasmic component
HS089_RS09485	COG1129	ABC transporter
HS089_RS09490	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS089_RS09505	COG0589	response to stress
HS089_RS09535	COG0835	chemotaxis
HS089_RS09545	COG1301	dicarboxylic acid transport
HS089_RS09555	COG0840	transmembrane signaling receptor activity
HS089_RS09570	COG0745	RESPONSE REGULATOR receiver
HS089_RS09595	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HS089_RS09610	COG3102	Protein conserved in bacteria
HS089_RS09630	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HS089_RS09635	COG1801	Protein of unknown function DUF72
HS089_RS09640	COG0582	viral genome integration into host DNA
HS089_RS09725	COG1802	Transcriptional regulator
HS089_RS09725	COG4626	Terminase
HS089_RS09730	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HS089_RS09740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HS089_RS09755	COG1403	HNH endonuclease
HS089_RS09780	COG3179	chitinase
HS089_RS09800	COG3646	Phage regulatory protein
HS089_RS09820	COG3436	PFAM IS66 Orf2 family protein
HS089_RS09825	COG4372	Transposase
HS089_RS09850	COG0740	serine-type endopeptidase activity
HS089_RS09950	COG2135	peptidase activity
HS089_RS09955	COG1335	isochorismatase
HS089_RS09965	COG0494	nUDIX hydrolase
HS089_RS09990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HS089_RS10000	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HS089_RS10005	COG0739	heme binding
HS089_RS10010	COG1560	Kdo2-lipid A biosynthetic process
HS089_RS10020	COG1737	Transcriptional regulator
HS089_RS10025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HS089_RS10030	COG0129	dihydroxy-acid dehydratase activity
HS089_RS10035	COG0800	Aldolase
HS089_RS10045	COG3141	response to X-ray
HS089_RS10055	COG2979	Protein of unknown function (DUF533)
HS089_RS10060	COG1770	oligopeptidase
HS089_RS10065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HS089_RS10070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HS089_RS10080	COG2372	response to copper ion
HS089_RS10085	COG1276	copper resistance
HS089_RS10095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HS089_RS10115	COG3008	intermembrane lipid transfer
HS089_RS10120	COG2995	paraquat-inducible protein a
HS089_RS10125	COG1956	GAF domain-containing protein
HS089_RS10240	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HS089_RS10270	COG2197	response regulator
HS089_RS10285	COG2814	Major facilitator Superfamily
HS089_RS10290	COG1414	Transcriptional regulator
HS089_RS10320	COG0768	penicillin binding
HS089_RS10325	COG2226	methyltransferase
HS089_RS10340	COG3716	PTS system mannose fructose sorbose family IID component
HS089_RS10345	COG3715	PTS system
HS089_RS10350	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS089_RS10350	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS089_RS10355	COG1253	flavin adenine dinucleotide binding
HS089_RS10360	COG2200	EAL domain
HS089_RS10365	COG1760	l-serine dehydratase
HS089_RS10385	COG0251	oxidation-reduction process
HS089_RS10390	COG1199	ATP-dependent helicase activity
HS089_RS10395	COG1214	PFAM Peptidase M22, glycoprotease
HS089_RS10400	COG3065	identical protein binding
HS089_RS10405	COG0318	PFAM AMP-dependent synthetase and ligase
HS089_RS10410	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HS089_RS10415	COG0473	3-isopropylmalate dehydrogenase activity
HS089_RS10420	COG0583	DNA-binding transcription factor activity
HS089_RS10430	COG2894	cell division
HS089_RS10445	COG0179	Fumarylacetoacetate (FAA) hydrolase
HS089_RS10475	COG2719	SpoVR family
HS089_RS10485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HS089_RS10495	COG1619	proteins homologs of microcin C7 resistance protein MccF
HS089_RS10520	COG0157	Belongs to the NadC ModD family
HS089_RS10530	COG1120	ATPase activity
HS089_RS10535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS089_RS10540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HS089_RS10555	COG1461	Dihydroxyacetone kinase
HS089_RS10560	COG2376	Dihydroxyacetone kinase
HS089_RS10565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HS089_RS10590	COG0789	Transcriptional regulator
HS089_RS10595	COG2200	EAL domain
HS089_RS10640	COG0012	GTP binding
HS089_RS10655	COG0527	aspartate kinase activity
HS089_RS10660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HS089_RS10665	COG0076	glutamate decarboxylase activity
HS089_RS10670	COG0659	secondary active sulfate transmembrane transporter activity
HS089_RS10700	COG2890	protein-(glutamine-N5) methyltransferase activity
HS089_RS10705	COG3094	Invasion gene expression up-regulator, SirB
HS089_RS10720	COG0387	Pfam Sodium calcium exchanger
HS089_RS10725	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HS089_RS10735	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HS089_RS10740	COG4932	domain protein
HS089_RS10745	COG2197	response regulator
HS089_RS10750	COG3850	Histidine kinase
HS089_RS10755	COG2223	nitrite transmembrane transporter activity
HS089_RS10760	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HS089_RS10765	COG1140	nitrate reductase beta subunit
HS089_RS10770	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HS089_RS10775	COG2181	nitrate reductase activity
HS089_RS10805	COG0788	formyltetrahydrofolate deformylase activity
HS089_RS10815	COG1752	Esterase of the alpha-beta hydrolase superfamily
HS089_RS10820	COG0745	RESPONSE REGULATOR receiver
HS089_RS10825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HS089_RS10840	COG1012	belongs to the aldehyde dehydrogenase family
HS089_RS10840	COG1454	alcohol dehydrogenase
HS089_RS10845	COG2095	MarC family integral membrane protein
HS089_RS10865	COG0444	Belongs to the ABC transporter superfamily
HS089_RS10875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HS089_RS10895	COG2350	Protein conserved in bacteria
HS089_RS10920	COG3047	cAMP biosynthetic process
HS089_RS10925	COG0217	transcriptional regulatory protein
HS089_RS10940	COG3706	GGDEF domain
HS089_RS10980	COG0009	L-threonylcarbamoyladenylate synthase
HS089_RS10985	COG1187	pseudouridine synthase activity
HS089_RS10995	COG1028	Short-chain dehydrogenase reductase Sdr
HS089_RS11000	COG0616	signal peptide processing
HS089_RS11015	COG0583	DNA-binding transcription factor activity
HS089_RS11030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HS089_RS11040	COG0671	phosphoesterase, PA-phosphatase related
HS089_RS11045	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HS089_RS11050	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HS089_RS11060	COG0023	Translation Initiation Factor
HS089_RS11070	COG1349	DNA-binding transcription factor activity
HS089_RS11080	COG5001	Diguanylate cyclase
HS089_RS11090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HS089_RS11090	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HS089_RS11095	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HS089_RS11115	COG4171	peptide transport system, permease
HS089_RS11140	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HS089_RS11145	COG1842	Phage shock protein A
HS089_RS11155	COG1983	PspC domain protein
HS089_RS11165	COG0366	Alpha amylase catalytic
HS089_RS11170	COG1653	transport
HS089_RS11175	COG1175	transmembrane transport
HS089_RS11180	COG0395	ABC-type sugar transport system, permease component
HS089_RS11185	COG1063	alcohol dehydrogenase
HS089_RS11190	COG1082	Xylose isomerase domain protein TIM barrel
HS089_RS11195	COG0673	inositol 2-dehydrogenase activity
HS089_RS11200	COG1554	hydrolase, family 65, central catalytic
HS089_RS11205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HS089_RS11210	COG3842	ATPase activity
HS089_RS11220	COG1609	Transcriptional regulator
HS089_RS11225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HS089_RS11230	COG3106	COG3106 Predicted ATPase
HS089_RS11245	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HS089_RS11250	COG4948	Mandelate Racemase Muconate Lactonizing
HS089_RS11255	COG2866	Carboxypeptidase
HS089_RS11260	COG4166	transmembrane transport
HS089_RS11280	COG1349	DNA-binding transcription factor activity
HS089_RS11285	COG0346	lactoylglutathione lyase activity
HS089_RS11295	COG1064	alcohol dehydrogenase
HS089_RS11300	COG0668	transmembrane transport
HS089_RS11305	COG3182	Iron-regulated membrane protein
HS089_RS11325	COG2840	Smr protein MutS2
HS089_RS11330	COG3706	GGDEF domain
HS089_RS11340	COG0840	transmembrane signaling receptor activity
HS089_RS11350	COG0513	Belongs to the DEAD box helicase family
HS089_RS11360	COG0589	response to stress
HS089_RS11370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HS089_RS11375	COG1013	pyruvate-flavodoxin oxidoreductase activity
HS089_RS11375	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HS089_RS11375	COG0674	pyruvate-flavodoxin oxidoreductase activity
HS089_RS11375	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HS089_RS11380	COG3042	response to heat
HS089_RS11385	COG3187	Heat shock protein
HS089_RS11390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HS089_RS11395	COG2911	Protein conserved in bacteria
HS089_RS11405	COG3784	Protein of unknown function (DUF1318)
HS089_RS11420	COG1643	Atp-dependent helicase
HS089_RS11425	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HS089_RS11430	COG1012	belongs to the aldehyde dehydrogenase family
HS089_RS11435	COG0657	acetylesterase activity
HS089_RS11435	COG2755	lipolytic protein G-D-S-L family
HS089_RS11440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HS089_RS11445	COG3038	cytochrome b561
HS089_RS11455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HS089_RS11460	COG2864	formate dehydrogenase
HS089_RS11465	COG0437	4 iron, 4 sulfur cluster binding
HS089_RS11470	COG0243	molybdopterin cofactor binding
HS089_RS11470	COG3383	formate dehydrogenase (NAD+) activity
HS089_RS11480	COG3059	membrane
HS089_RS11500	COG0840	transmembrane signaling receptor activity
HS089_RS11525	COG3121	Chaperone
HS089_RS11535	COG0583	DNA-binding transcription factor activity
HS089_RS11540	COG1227	inorganic diphosphatase activity
HS089_RS11545	COG5383	Protein conserved in bacteria
HS089_RS11555	COG2841	Protein conserved in bacteria
HS089_RS11565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HS089_RS11570	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HS089_RS11575	COG1275	C4-dicarboxylate transporter malic acid transport protein
HS089_RS11580	COG0500	methyltransferase
HS089_RS11590	COG0697	spore germination
HS089_RS11600	COG3135	benzoate transporter
HS089_RS11605	COG1396	sequence-specific DNA binding
HS089_RS11610	COG0826	peptidase U32
HS089_RS11625	COG1294	oxidase, subunit
HS089_RS11630	COG1271	oxidase subunit
HS089_RS11640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HS089_RS11645	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HS089_RS11650	COG3842	ATPase activity
HS089_RS11655	COG1176	ABC-type spermidine putrescine transport system, permease component I
HS089_RS11660	COG1177	transmembrane transport
HS089_RS11700	COG0747	negative chemotaxis
HS089_RS11710	COG3238	Protein conserved in bacteria
HS089_RS11715	COG1247	-acetyltransferase
HS089_RS11725	COG2130	NADP-dependent
HS089_RS11745	COG0840	transmembrane signaling receptor activity
HS089_RS11750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HS089_RS11755	COG1473	amidohydrolase
HS089_RS11760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HS089_RS11765	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HS089_RS11780	COG1126	abc transporter atp-binding protein
HS089_RS11785	COG3321	synthase
HS089_RS11785	COG1028	Short-chain dehydrogenase reductase Sdr
HS089_RS11785	COG0604	alcohol dehydrogenase
HS089_RS11790	COG0583	DNA-binding transcription factor activity
HS089_RS11795	COG0625	glutathione transferase activity
HS089_RS11810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HS089_RS11815	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HS089_RS11830	COG0384	phenazine biosynthesis protein PhzF
HS089_RS11840	COG2181	nitrate reductase activity
HS089_RS11845	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HS089_RS11850	COG1140	nitrate reductase beta subunit
HS089_RS11855	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HS089_RS11860	COG2223	nitrite transmembrane transporter activity
HS089_RS11885	COG0697	spore germination
HS089_RS11895	COG0437	4 iron, 4 sulfur cluster binding
HS089_RS11900	COG2864	formate dehydrogenase
HS089_RS11905	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HS089_RS11910	COG0488	(ABC) transporter
HS089_RS11925	COG1764	response to oxidative stress
HS089_RS11930	COG1028	Short-chain dehydrogenase reductase Sdr
HS089_RS11935	COG2610	gluconate transmembrane transporter activity
HS089_RS11940	COG1250	3-hydroxyacyl-CoA dehydrogenase
HS089_RS11950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HS089_RS11955	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HS089_RS11965	COG4608	Belongs to the ABC transporter superfamily
HS089_RS11970	COG0444	Belongs to the ABC transporter superfamily
HS089_RS11975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HS089_RS11980	COG0601	transmembrane transport
HS089_RS11985	COG0747	negative chemotaxis
HS089_RS11990	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HS089_RS12005	COG0840	transmembrane signaling receptor activity
HS089_RS12025	COG1649	PFAM Uncharacterised BCR, COG1649
HS089_RS12030	COG4628	conserved protein (DUF2132)
HS089_RS12055	COG3121	Chaperone
HS089_RS12070	COG3121	Chaperone
HS089_RS12100	COG3781	membrane
HS089_RS12130	COG1012	belongs to the aldehyde dehydrogenase family
HS089_RS12135	COG0583	DNA-binding transcription factor activity
HS089_RS12150	COG1846	Transcriptional regulator
HS089_RS12165	COG0697	spore germination
HS089_RS12170	COG2814	Major facilitator Superfamily
HS089_RS12180	COG1122	ATPase activity
HS089_RS12205	COG3706	GGDEF domain
HS089_RS12220	COG4221	oxidoreductase activity
HS089_RS12225	COG1802	Transcriptional regulator
HS089_RS12235	COG0246	Mannitol dehydrogenase
HS089_RS12245	COG4948	Mandelate Racemase Muconate Lactonizing
HS089_RS12260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HS089_RS12275	COG0243	molybdopterin cofactor binding
HS089_RS12280	COG0437	4 iron, 4 sulfur cluster binding
HS089_RS12285	COG3302	dmso reductase anchor subunit
HS089_RS12290	COG3381	protein complex oligomerization
HS089_RS12300	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HS089_RS12305	COG1940	carbohydrate kinase activity
HS089_RS12310	COG0583	DNA-binding transcription factor activity
HS089_RS12315	COG2814	Major facilitator Superfamily
HS089_RS12325	COG2205	protein histidine kinase activity
HS089_RS12330	COG0745	RESPONSE REGULATOR receiver
HS089_RS12345	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HS089_RS12355	COG3591	Belongs to the peptidase S1B family
HS089_RS12370	COG0628	permease
HS089_RS12375	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HS089_RS12380	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HS089_RS12390	COG0531	amino acid
HS089_RS12400	COG3136	membrane protein required for alginate biosynthesis
HS089_RS12405	COG0745	RESPONSE REGULATOR receiver
HS089_RS12410	COG1823	symporter activity
HS089_RS12415	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HS089_RS12425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HS089_RS12435	COG2205	protein histidine kinase activity
HS089_RS12450	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HS089_RS12450	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HS089_RS12460	COG5339	Protein conserved in bacteria
HS089_RS12465	COG1609	Transcriptional regulator
HS089_RS12470	COG1263	PTS System
HS089_RS12470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS089_RS12475	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HS089_RS12485	COG0673	inositol 2-dehydrogenase activity
HS089_RS12535	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HS089_RS12545	COG0625	glutathione transferase activity
HS089_RS12550	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HS089_RS12565	COG3895	Periplasmic Protein
HS089_RS12590	COG1566	PFAM secretion protein HlyD family protein
HS089_RS12600	COG2032	superoxide dismutase activity
HS089_RS12605	COG4989	oxidoreductase activity
HS089_RS12610	COG3313	Fe-S protein
HS089_RS12615	COG1309	transcriptional regulator
HS089_RS12620	COG1902	pentaerythritol trinitrate reductase activity
HS089_RS12625	COG0346	lactoylglutathione lyase activity
HS089_RS12635	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HS089_RS12640	COG0791	NLP P60 protein
HS089_RS12645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HS089_RS12650	COG2814	Major facilitator Superfamily
HS089_RS12665	COG0583	DNA-binding transcription factor activity
HS089_RS12670	COG2814	Major facilitator Superfamily
HS089_RS12675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HS089_RS12680	COG0307	riboflavin synthase, alpha
HS089_RS12705	COG0251	oxidation-reduction process
HS089_RS12725	COG3300	MHYT domain
HS089_RS12725	COG5001	Diguanylate cyclase
HS089_RS12730	COG0386	Belongs to the glutathione peroxidase family
HS089_RS12735	COG0628	permease
HS089_RS12750	COG1028	Short-chain dehydrogenase reductase Sdr
HS089_RS12755	COG2378	regulation of single-species biofilm formation
HS089_RS12775	COG3121	Chaperone
HS089_RS12780	COG3188	usher protein
HS089_RS12795	COG4977	sequence-specific DNA binding
HS089_RS12825	COG1120	ATPase activity
HS089_RS12830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS089_RS12835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HS089_RS12840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HS089_RS12855	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HS089_RS12865	COG1012	belongs to the aldehyde dehydrogenase family
HS089_RS12880	COG1113	amino acid transport
HS089_RS12890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS089_RS12905	COG0765	amino acid transport
HS089_RS12915	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HS089_RS12920	COG0437	4 iron, 4 sulfur cluster binding
HS089_RS12930	COG2414	aldehyde ferredoxin oxidoreductase
HS089_RS12935	COG0437	4 iron, 4 sulfur cluster binding
HS089_RS12985	COG1464	Belongs to the NlpA lipoprotein family
HS089_RS12990	COG2011	ABC-type metal ion transport system permease component
HS089_RS13000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS089_RS13010	COG2267	carboxylic ester hydrolase activity
HS089_RS13015	COG0531	amino acid
HS089_RS13030	COG1376	ErfK ybiS ycfS ynhG family protein
HS089_RS13045	COG0719	Fe-S assembly protein
HS089_RS13050	COG0396	ATPase activity
HS089_RS13055	COG0719	Fe-S assembly protein
HS089_RS13060	COG0316	Belongs to the HesB IscA family
HS089_RS13065	COG0583	DNA-binding transcription factor activity
HS089_RS13080	COG2050	protein possibly involved in aromatic compounds catabolism
HS089_RS13085	COG0277	FAD linked oxidase domain protein
HS089_RS13085	COG0247	lactate metabolic process
HS089_RS13090	COG0628	permease
HS089_RS13105	COG0738	Major facilitator superfamily
HS089_RS13110	COG2271	Major facilitator Superfamily
HS089_RS13125	COG4670	ketone body catabolic process
HS089_RS13130	COG1960	acyl-CoA dehydrogenase activity
HS089_RS13135	COG2207	Transcriptional regulator
HS089_RS13135	COG1917	Cupin 2, conserved barrel domain protein
HS089_RS13140	COG2086	electron transfer activity
HS089_RS13145	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HS089_RS13150	COG0644	oxidoreductase
HS089_RS13155	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HS089_RS13160	COG0318	PFAM AMP-dependent synthetase and ligase
HS089_RS13165	COG0574	Belongs to the PEP-utilizing enzyme family
HS089_RS13165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HS089_RS13175	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HS089_RS13180	COG4256	Hemin uptake protein
HS089_RS13185	COG4771	TonB-dependent receptor
HS089_RS13190	COG3720	iron ion transport
HS089_RS13195	COG4558	Periplasmic binding protein
HS089_RS13200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS089_RS13220	COG0791	NLP P60 protein
HS089_RS13230	COG0386	Belongs to the glutathione peroxidase family
HS089_RS13265	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HS089_RS13285	COG3137	Salt-induced outer membrane protein
HS089_RS13290	COG1105	Belongs to the carbohydrate kinase PfkB family
HS089_RS13295	COG3001	Fructosamine kinase
HS089_RS13305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HS089_RS13310	COG1028	Short-chain dehydrogenase reductase Sdr
HS089_RS13315	COG1988	membrane-bound metal-dependent
HS089_RS13320	COG1823	symporter activity
HS089_RS13330	COG0753	catalase activity
HS089_RS13340	COG1486	melibiose metabolic process
HS089_RS13345	COG1917	Cupin 2, conserved barrel domain protein
HS089_RS13345	COG2169	Transcriptional regulator
HS089_RS13350	COG1447	Phosphotransferase system cellobiose-specific component IIA
HS089_RS13355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HS089_RS13360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HS089_RS13365	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HS089_RS13375	COG0322	excinuclease ABC activity
HS089_RS13385	COG3678	ATP-independent chaperone mediated protein folding
HS089_RS13415	COG0708	Exodeoxyribonuclease III
HS089_RS13420	COG0398	Pfam SNARE associated Golgi protein
HS089_RS13425	COG0398	Pfam SNARE associated Golgi protein
HS089_RS13430	COG4134	Bacterial extracellular solute-binding protein
HS089_RS13435	COG4135	transport system, permease component
HS089_RS13440	COG4136	ATPase activity
HS089_RS13445	COG2897	thiosulfate sulfurtransferase activity
HS089_RS13450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HS089_RS13455	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HS089_RS13460	COG0494	nUDIX hydrolase
HS089_RS13475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HS089_RS13485	COG0778	Nitroreductase
HS089_RS13490	COG0616	signal peptide processing
HS089_RS13495	COG0252	asparaginase activity
HS089_RS13500	COG1335	isochorismatase
HS089_RS13505	COG2814	Major facilitator Superfamily
HS089_RS13510	COG1349	DNA-binding transcription factor activity
HS089_RS13515	COG0667	Aldo Keto reductase
HS089_RS13520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS089_RS13525	COG0191	fructose-bisphosphate aldolase activity
HS089_RS13530	COG1063	alcohol dehydrogenase
HS089_RS13535	COG2271	Major facilitator Superfamily
HS089_RS13540	COG1063	alcohol dehydrogenase
HS089_RS13555	COG3139	Protein of unknown function (DUF1315)
HS089_RS13575	COG0656	L-ascorbic acid biosynthetic process
HS089_RS13580	COG3713	MltA-interacting MipA family protein
HS089_RS13585	COG2766	serine protein kinase
HS089_RS13595	COG2226	methyltransferase
HS089_RS13600	COG2199	diguanylate cyclase activity
HS089_RS13605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HS089_RS13615	COG2207	Transcriptional regulator
HS089_RS13620	COG2807	transmembrane transport
HS089_RS13625	COG0504	CTP synthase activity
HS089_RS13630	COG3189	MarR family transcriptional regulator
HS089_RS13635	COG3042	response to heat
HS089_RS13640	COG2199	diguanylate cyclase activity
HS089_RS13640	COG2203	Gaf domain
HS089_RS13655	COG2261	transglycosylase associated protein
HS089_RS13660	COG3383	formate dehydrogenase (NAD+) activity
HS089_RS13675	COG3615	Tellurite resistance protein tehB
HS089_RS13685	COG3443	Belongs to the bacterial solute-binding protein 9 family
HS089_RS13690	COG1124	(ABC) transporter
HS089_RS13700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HS089_RS13705	COG0601	transmembrane transport
HS089_RS13710	COG0747	negative chemotaxis
HS089_RS13715	COG4771	TonB-dependent receptor
HS089_RS13780	COG0431	NADPH-dependent FMN reductase
HS089_RS13785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HS089_RS13800	COG0538	isocitrate dehydrogenase activity
HS089_RS13830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HS089_RS13845	COG2850	peptidyl-arginine hydroxylation
HS089_RS13865	COG1177	transmembrane transport
HS089_RS13875	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HS089_RS13885	COG4591	ABC-type transport system involved in lipoprotein release permease component
HS089_RS13890	COG1136	(ABC) transporter
HS089_RS13895	COG4591	ABC-type transport system involved in lipoprotein release permease component
HS089_RS13900	COG4763	Acyl-transferase
HS089_RS13905	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HS089_RS13910	COG1376	ErfK ybiS ycfS ynhG family protein
HS089_RS13910	COG1388	LysM domain
HS089_RS13920	COG1309	transcriptional regulator
HS089_RS13930	COG3134	Outer membrane lipoprotein
HS089_RS13935	COG1252	NADH dehydrogenase
HS089_RS13960	COG5633	Lipoprotein
HS089_RS13965	COG0537	adenosine 5'-monophosphoramidase activity
HS089_RS13970	COG0583	DNA-binding transcription factor activity
HS089_RS13980	COG0309	Hydrogenase expression formation protein (HypE)
HS089_RS13985	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HS089_RS13990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HS089_RS13995	COG2223	nitrite transmembrane transporter activity
HS089_RS14005	COG0534	Mate efflux family protein
HS089_RS14015	COG0583	DNA-binding transcription factor activity
HS089_RS14030	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HS089_RS14035	COG1027	Aspartate ammonia-lyase
HS089_RS14040	COG0583	DNA-binding transcription factor activity
HS089_RS14060	COG1595	DNA-templated transcription, initiation
HS089_RS14065	COG3712	iron ion homeostasis
HS089_RS14070	COG4772	TonB-dependent receptor
HS089_RS14075	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HS089_RS14080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS089_RS14085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS089_RS14090	COG1120	ATPase activity
HS089_RS14115	COG0477	Major facilitator Superfamily
HS089_RS14120	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HS089_RS14135	COG0084	hydrolase, TatD family'
HS089_RS14140	COG0470	DNA polymerase III
HS089_RS14150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HS089_RS14155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HS089_RS14160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HS089_RS14195	COG1399	metal-binding, possibly nucleic acid-binding protein
HS089_RS14205	COG0564	pseudouridine synthase activity
HS089_RS14210	COG1530	ribonuclease E activity
HS089_RS14215	COG0583	DNA-binding transcription factor activity
HS089_RS14220	COG2814	Major facilitator Superfamily
HS089_RS14250	COG4786	Flagellar basal body rod
HS089_RS14255	COG4787	bacterial-type flagellum-dependent cell motility
HS089_RS14270	COG1558	bacterial-type flagellum-dependent cell motility
HS089_RS14310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HS089_RS14350	COG3038	cytochrome b561
HS089_RS14365	COG1560	Kdo2-lipid A biosynthetic process
HS089_RS14375	COG2199	diguanylate cyclase activity
HS089_RS14385	COG5645	(Lipo)protein
HS089_RS14405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HS089_RS14460	COG3381	protein complex oligomerization
HS089_RS14495	COG2962	Rard protein
HS089_RS14500	COG2990	Protein conserved in bacteria
HS089_RS14505	COG1702	phosphate starvation-inducible protein PhoH
HS089_RS14525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HS089_RS14530	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HS089_RS14530	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HS089_RS14530	COG0506	proline dehydrogenase activity
HS089_RS14535	COG3755	Protein conserved in bacteria
HS089_RS14540	COG1309	transcriptional regulator
HS089_RS14550	COG3729	General stress protein
HS089_RS14570	COG0640	Transcriptional regulator
HS089_RS14590	COG1136	(ABC) transporter
HS089_RS14590	COG0577	efflux transmembrane transporter activity
HS089_RS14600	COG0577	efflux transmembrane transporter activity
HS089_RS14600	COG1136	(ABC) transporter
HS089_RS14615	COG0672	)-iron permease
HS089_RS14620	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HS089_RS14625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HS089_RS14630	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HS089_RS14630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HS089_RS14680	COG0813	purine-nucleoside phosphorylase activity
HS089_RS14695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS089_RS14700	COG1120	ATPase activity
HS089_RS14710	COG0723	plastoquinol--plastocyanin reductase activity
HS089_RS14715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HS089_RS14715	COG2857	Cytochrome c1
HS089_RS14735	COG0670	Belongs to the BI1 family
HS089_RS14760	COG1832	CoA-binding protein
HS089_RS14775	COG0210	DNA helicase
HS089_RS14780	COG3304	Inner membrane component domain
HS089_RS14785	COG1289	transmembrane transporter activity
HS089_RS14790	COG3070	regulator of competence-specific genes
HS089_RS14810	COG1067	ATP-dependent peptidase activity
HS089_RS14820	COG3130	regulation of translation
HS089_RS14825	COG3009	Protein conserved in bacteria
HS089_RS14830	COG3008	intermembrane lipid transfer
HS089_RS14830	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HS089_RS14835	COG2995	paraquat-inducible protein a
HS089_RS14840	COG0488	(ABC) transporter
HS089_RS14850	COG3217	Mosc domain protein beta barrel domain protein
HS089_RS14850	COG0633	Ferredoxin
HS089_RS14865	COG0431	NADPH-dependent FMN reductase
HS089_RS14870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HS089_RS14880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HS089_RS14885	COG1116	anion transmembrane transporter activity
HS089_RS14890	COG0308	aminopeptidase N
HS089_RS15065	COG3772	lysozyme
HS089_RS15155	COG0582	viral genome integration into host DNA
HS089_RS15175	COG1448	Aminotransferase
HS089_RS15180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HS089_RS15185	COG3108	Peptidase M15
HS089_RS15190	COG2989	Protein conserved in bacteria
HS089_RS15200	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HS089_RS15210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HS089_RS15215	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HS089_RS15220	COG3173	Aminoglycoside phosphotransferase
HS089_RS15235	COG3214	Protein conserved in bacteria
HS089_RS15250	COG2333	competence protein COMEC
HS089_RS15250	COG0658	competence protein
HS089_RS15255	COG0776	regulation of translation
HS089_RS15260	COG0539	negative regulation of cytoplasmic translation
HS089_RS15270	COG0501	Belongs to the peptidase M48B family
HS089_RS15285	COG2323	membrane
HS089_RS15290	COG1944	ATP diphosphatase activity
HS089_RS15295	COG2116	formate transmembrane transporter activity
HS089_RS15300	COG1882	Formate acetyltransferase
HS089_RS15435	COG4695	Portal protein
HS089_RS15490	COG4974	Belongs to the 'phage' integrase family
HS089_RS15495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HS089_RS15500	COG0531	amino acid
HS089_RS15510	COG1335	isochorismatase
HS089_RS15515	COG3302	dmso reductase anchor subunit
HS089_RS15520	COG0437	4 iron, 4 sulfur cluster binding
HS089_RS15525	COG0243	molybdopterin cofactor binding
HS089_RS15535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HS089_RS15545	COG1674	ftsk spoiiie
HS089_RS15545	COG1178	ABC-type Fe3 transport system permease component
HS089_RS15555	COG0492	ferredoxin-NADP+ reductase activity
HS089_RS15560	COG4988	ABC transporter
HS089_RS15565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HS089_RS15580	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HS089_RS15585	COG0583	DNA-binding transcription factor activity
HS089_RS15595	COG1335	isochorismatase
HS089_RS15615	COG1177	transmembrane transport
HS089_RS15620	COG1176	ABC-type spermidine putrescine transport system, permease component I
HS089_RS15625	COG3842	ATPase activity
HS089_RS15630	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HS089_RS15685	COG0583	DNA-binding transcription factor activity
HS089_RS15690	COG3226	Transcriptional regulator
HS089_RS15695	COG0738	Major facilitator superfamily
HS089_RS15700	COG0561	phosphatase activity
HS089_RS15710	COG2814	Major facilitator Superfamily
HS089_RS15715	COG0671	phosphoesterase, PA-phosphatase related
HS089_RS15720	COG1349	DNA-binding transcription factor activity
HS089_RS15725	COG1686	Belongs to the peptidase S11 family
HS089_RS15730	COG0625	glutathione transferase activity
HS089_RS15735	COG2133	pyrroloquinoline quinone binding
HS089_RS15845	COG1446	asparaginase
HS089_RS15855	COG0303	'Molybdopterin
HS089_RS15860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HS089_RS15865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HS089_RS15870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HS089_RS15875	COG1882	Formate acetyltransferase
HS089_RS15880	COG0561	phosphatase activity
HS089_RS15890	COG0488	(ABC) transporter
HS089_RS15895	COG1376	ErfK ybiS ycfS ynhG family protein
HS089_RS15900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HS089_RS15915	COG2194	sulfuric ester hydrolase activity
HS089_RS15920	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HS089_RS15935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS089_RS15940	COG0765	amino acid transport
HS089_RS15945	COG1126	abc transporter atp-binding protein
HS089_RS15950	COG0668	transmembrane transport
HS089_RS15965	COG4774	siderophore transport
HS089_RS15975	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HS089_RS15985	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HS089_RS15990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HS089_RS16000	COG0471	metal ion transport
HS089_RS16010	COG2188	Transcriptional regulator
HS089_RS16015	COG0513	Belongs to the DEAD box helicase family
HS089_RS16020	COG1309	transcriptional regulator
HS089_RS16030	COG1131	(ABC) transporter
HS089_RS16035	COG0842	Transport permease protein
HS089_RS16040	COG0842	Transport permease protein
HS089_RS16050	COG3568	Endonuclease Exonuclease Phosphatase
HS089_RS16055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HS089_RS16060	COG0392	lysyltransferase activity
HS089_RS16065	COG0670	Belongs to the BI1 family
HS089_RS16070	COG0314	molybdopterin synthase activity
HS089_RS16075	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HS089_RS16085	COG0521	Mo-molybdopterin cofactor biosynthetic process
HS089_RS16115	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HS089_RS16135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HS089_RS16140	COG1881	PFAM PEBP family protein
HS089_RS16170	COG4677	pectinesterase activity
HS089_RS16185	COG0561	phosphatase activity
HS089_RS16195	COG4149	molybdate abc transporter
HS089_RS16200	COG0725	ABC transporter, periplasmic molybdate-binding protein
HS089_RS16210	COG2005	Transcriptional regulator
HS089_RS16210	COG3585	molybdate ion transport
HS089_RS16215	COG1119	ATPase activity
HS089_RS16220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HS089_RS16225	COG1085	galactose-1-phosphate uridylyltransferase
HS089_RS16235	COG2017	converts alpha-aldose to the beta-anomer
HS089_RS16245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HS089_RS16255	COG1230	cation diffusion facilitator family transporter
HS089_RS16260	COG3201	nicotinamide mononucleotide transporter
HS089_RS16300	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HS089_RS16305	COG2885	chlorophyll binding
HS089_RS16315	COG3064	Membrane
HS089_RS16320	COG0848	biopolymer transport protein
HS089_RS16325	COG0811	peptide transport
HS089_RS16330	COG0824	Thioesterase
HS089_RS16335	COG3790	cyd operon protein YbgE
HS089_RS16340	COG4890	Cyd operon protein YbgT
HS089_RS16345	COG1294	oxidase, subunit
HS089_RS16350	COG1271	oxidase subunit
HS089_RS16355	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HS089_RS16365	COG4865	methylaspartate mutase activity
HS089_RS16370	COG3799	methylaspartate ammonia-lyase activity
HS089_RS16385	COG1301	dicarboxylic acid transport
HS089_RS16395	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HS089_RS16395	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HS089_RS16405	COG0583	DNA-binding transcription factor activity
HS089_RS16410	COG1648	precorrin-2 dehydrogenase activity
HS089_RS16410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HS089_RS16420	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HS089_RS16430	COG0508	dehydrogenase complex catalyzes the overall conversion of
HS089_RS16435	COG0567	Dehydrogenase, E1 component
HS089_RS16440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HS089_RS16445	COG1053	succinate dehydrogenase
HS089_RS16450	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HS089_RS16455	COG2009	succinate dehydrogenase
HS089_RS16465	COG3157	Type VI secretion system effector, Hcp
HS089_RS16480	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
HS089_RS16485	COG3180	Ammonia monooxygenase
HS089_RS16515	COG1984	allophanate hydrolase subunit 2
HS089_RS16520	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HS089_RS16535	COG5464	transposase or invertase
HS089_RS16545	COG3272	Protein of unknown function (DUF1722)
HS089_RS16575	COG2205	protein histidine kinase activity
HS089_RS16580	COG0745	RESPONSE REGULATOR receiver
HS089_RS16585	COG0033	Phosphoglucomutase
HS089_RS16590	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HS089_RS16595	COG0596	Alpha beta hydrolase
HS089_RS16605	COG0716	FMN binding
HS089_RS16615	COG0735	belongs to the Fur family
HS089_RS16620	COG0583	DNA-binding transcription factor activity
HS089_RS16625	COG1053	succinate dehydrogenase
HS089_RS16655	COG2190	(PTS) system
HS089_RS16655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS089_RS16655	COG1263	PTS System
HS089_RS16665	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HS089_RS16670	COG1846	Transcriptional regulator
HS089_RS16670	COG1940	carbohydrate kinase activity
HS089_RS16675	COG0647	UMP catabolic process
HS089_RS16680	COG0367	asparagine synthase
HS089_RS16725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HS089_RS16735	COG1702	phosphate starvation-inducible protein PhoH
HS089_RS16745	COG4535	Mg2 and Co2 transporter CorC
HS089_RS16760	COG0765	amino acid transport
HS089_RS16765	COG0765	amino acid transport
HS089_RS16770	COG1126	abc transporter atp-binding protein
HS089_RS16780	COG2888	peptidyl-tyrosine sulfation
HS089_RS16795	COG1466	dna polymerase III delta subunit
HS089_RS16805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HS089_RS16815	COG0799	negative regulation of ribosome biogenesis
HS089_RS16825	COG0768	penicillin binding
HS089_RS16830	COG0772	Belongs to the SEDS family
HS089_RS16835	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HS089_RS16840	COG1686	Belongs to the peptidase S11 family
HS089_RS16865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HS089_RS16885	COG3069	C4-dicarboxylate transmembrane transporter activity
HS089_RS16890	COG4565	transcriptional regulatory protein
HS089_RS16895	COG3290	protein histidine kinase activity
HS089_RS16900	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HS089_RS16910	COG2301	Belongs to the HpcH HpaI aldolase family
HS089_RS16915	COG3051	citrate lyase alpha subunit
HS089_RS16930	COG0471	metal ion transport
HS089_RS16935	COG3719	Belongs to the RNase T2 family
HS089_RS16950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HS089_RS16980	COG3634	alkyl hydroperoxide reductase activity
HS089_RS16990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HS089_RS16995	COG0583	DNA-binding transcription factor activity
HS089_RS17000	COG3969	phosphoadenosine phosphosulfate
HS089_RS17005	COG1475	DNA binding
HS089_RS17010	COG0436	Aminotransferase
HS089_RS17015	COG0371	Dehydrogenase
HS089_RS17020	COG2879	small protein
HS089_RS17025	COG1966	Carbon starvation protein
HS089_RS17035	COG1028	Short-chain dehydrogenase reductase Sdr
HS089_RS17040	COG1535	isochorismatase
HS089_RS17040	COG3433	isochorismatase activity
HS089_RS17045	COG1021	2,3-dihydroxybenzoate-AMP ligase
HS089_RS17050	COG1169	isochorismate synthase
HS089_RS17055	COG4592	Periplasmic binding protein
HS089_RS17065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS089_RS17070	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS089_RS17075	COG1120	ATPase activity
HS089_RS17080	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HS089_RS17085	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HS089_RS17085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HS089_RS17090	COG3251	PFAM MbtH domain protein
HS089_RS17095	COG2382	esterase
HS089_RS17100	COG4771	TonB-dependent receptor
HS089_RS17150	COG2315	Protein conserved in bacteria
HS089_RS17160	COG0668	transmembrane transport
HS089_RS17180	COG2211	Major facilitator Superfamily
HS089_RS17185	COG1113	amino acid transport
HS089_RS17205	COG3300	MHYT domain
HS089_RS17205	COG5001	Diguanylate cyclase
HS089_RS17220	COG3059	membrane
HS089_RS17230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HS089_RS17235	COG2207	Transcriptional regulator
HS089_RS17240	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HS089_RS17245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS089_RS17250	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS089_RS17255	COG1538	Outer membrane efflux protein
HS089_RS17260	COG0745	RESPONSE REGULATOR receiver
HS089_RS17265	COG5002	protein histidine kinase activity
HS089_RS17280	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HS089_RS17280	COG0321	lipoyl(octanoyl) transferase activity
HS089_RS17285	COG0243	molybdopterin cofactor binding
HS089_RS17310	COG3005	denitrification pathway
HS089_RS17315	COG0745	RESPONSE REGULATOR receiver
HS089_RS17320	COG1879	ABC-type sugar transport system periplasmic component
HS089_RS17325	COG2205	protein histidine kinase activity
HS089_RS17325	COG2198	Histidine kinase
HS089_RS17325	COG0784	Response regulator, receiver
HS089_RS17390	COG2501	S4 domain
HS089_RS17395	COG1988	membrane-bound metal-dependent
HS089_RS17405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HS089_RS17415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HS089_RS17420	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HS089_RS17425	COG0549	Belongs to the carbamate kinase family
HS089_RS17435	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HS089_RS17440	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HS089_RS17445	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HS089_RS17450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HS089_RS17455	COG3257	ureidoglycine aminohydrolase activity
HS089_RS17460	COG1929	Belongs to the glycerate kinase type-1 family
HS089_RS17465	COG2233	PERMEase
HS089_RS17475	COG1953	Uracil, thiamine, allantoin
HS089_RS17485	COG2084	Dehydrogenase
HS089_RS17490	COG3622	Belongs to the hyi family
HS089_RS17495	COG3960	tartronate-semialdehyde synthase activity
HS089_RS17530	COG1464	Belongs to the NlpA lipoprotein family
HS089_RS17535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HS089_RS17540	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HS089_RS17545	COG4181	ATPase activity
HS089_RS17550	COG2755	lipolytic protein G-D-S-L family
HS089_RS17555	COG0300	oxidoreductase activity
HS089_RS17560	COG3118	belongs to the thioredoxin family
HS089_RS17565	COG0390	transport system, permease component
HS089_RS17570	COG4619	ABC transporter
HS089_RS17575	COG0330	HflC and HflK could
HS089_RS17580	COG1585	Membrane protein implicated in regulation of membrane protease activity
HS089_RS17600	COG4771	TonB-dependent receptor
HS089_RS17605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HS089_RS17615	COG3721	Heme iron utilization protein
HS089_RS17625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS089_RS17635	COG2217	Heavy metal translocating P-type atpase
HS089_RS17640	COG3735	TraB family
HS089_RS17645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HS089_RS17655	COG2223	nitrite transmembrane transporter activity
HS089_RS17660	COG4651	solute:proton antiporter activity
HS089_RS17660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HS089_RS17665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS089_RS17710	COG2832	Protein of unknown function (DUF454)
HS089_RS17715	COG3923	Primosomal replication protein n
HS089_RS17725	COG3264	Mechanosensitive ion channel
HS089_RS17725	COG1196	nuclear chromosome segregation
HS089_RS17730	COG1309	transcriptional regulator
HS089_RS17735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS089_RS17740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HS089_RS17755	COG0110	maltose O-acetyltransferase activity
HS089_RS17775	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HS089_RS17780	COG5507	3-demethylubiquinone-9 3-methyltransferase
HS089_RS17785	COG2364	Membrane
HS089_RS17790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HS089_RS17810	COG3695	enzyme binding
HS089_RS17815	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HS089_RS17820	COG1946	Acyl-CoA thioesterase
HS089_RS17825	COG0004	ammonium transporteR
HS089_RS17830	COG0347	Belongs to the P(II) protein family
HS089_RS17835	COG1132	(ABC) transporter
HS089_RS17840	COG1132	(ABC) transporter
HS089_RS17845	COG1522	sequence-specific DNA binding
HS089_RS17860	COG4533	DNA binding
HS089_RS17870	COG0824	Thioesterase
HS089_RS17875	COG1555	photosystem II stabilization
HS089_RS17880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HS089_RS17885	COG0776	regulation of translation
HS089_RS17890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HS089_RS17910	COG0271	Belongs to the BolA IbaG family
HS089_RS17915	COG3056	Lipoprotein
HS089_RS17920	COG2223	nitrite transmembrane transporter activity
HS089_RS17925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HS089_RS17930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HS089_RS17935	COG1845	cytochrome c oxidase, subunit III
HS089_RS17940	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HS089_RS17950	COG2814	Major facilitator Superfamily
HS089_RS17985	COG0142	geranyltranstransferase activity
HS089_RS17995	COG0667	Aldo Keto reductase
HS089_RS18000	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HS089_RS18005	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HS089_RS18020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HS089_RS18020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HS089_RS18030	COG4238	major outer membrane lipoprotein
HS089_RS18050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HS089_RS18055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HS089_RS18060	COG1862	Preprotein translocase
HS089_RS18070	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HS089_RS18080	COG0450	alkyl hydroperoxide reductase
HS089_RS18085	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HS089_RS18095	COG1335	isochorismatase
HS089_RS18100	COG0583	DNA-binding transcription factor activity
HS089_RS18105	COG0366	Alpha amylase catalytic
HS089_RS18120	COG5002	protein histidine kinase activity
HS089_RS18130	COG0420	3'-5' exonuclease activity
HS089_RS18135	COG0419	ATPase involved in DNA repair
HS089_RS18140	COG2814	Major facilitator Superfamily
HS089_RS18145	COG1940	carbohydrate kinase activity
HS089_RS18160	COG4126	flavin adenine dinucleotide binding
HS089_RS18180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HS089_RS18185	COG3706	GGDEF domain
HS089_RS18195	COG1785	Belongs to the alkaline phosphatase family
HS089_RS18210	COG1181	Belongs to the D-alanine--D-alanine ligase family
HS089_RS18230	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HS089_RS18235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HS089_RS18240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HS089_RS18250	COG0113	porphobilinogen synthase activity
HS089_RS18255	COG2175	clavaminate synthase activity
HS089_RS18260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HS089_RS18265	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HS089_RS18270	COG4521	taurine ABC transporter
HS089_RS18285	COG2271	Major facilitator Superfamily
HS089_RS18290	COG1840	ABC-type Fe3 transport system, periplasmic component
HS089_RS18300	COG3842	ATPase activity
HS089_RS18305	COG2040	homocysteine
HS089_RS18310	COG0833	amino acid
HS089_RS18315	COG2814	Major facilitator Superfamily
HS089_RS18350	COG1414	Transcriptional regulator
HS089_RS18380	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HS089_RS18395	COG1609	Transcriptional regulator
HS089_RS18410	COG0110	maltose O-acetyltransferase activity
HS089_RS18420	COG2079	MmgE PrpD family protein
HS089_RS18425	COG0372	Belongs to the citrate synthase family
HS089_RS18435	COG3829	transcription factor binding
HS089_RS18445	COG1280	lysine exporter protein (LysE YggA)
HS089_RS18450	COG3706	GGDEF domain
HS089_RS18455	COG0348	domain, Protein
HS089_RS18460	COG1737	Transcriptional regulator
HS089_RS18470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS089_RS18475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS089_RS18480	COG1120	ATPase activity
HS089_RS18485	COG4774	siderophore transport
HS089_RS18505	COG0583	DNA-binding transcription factor activity
HS089_RS18525	COG3069	C4-dicarboxylate transmembrane transporter activity
HS089_RS18530	COG2195	Cleaves the N-terminal amino acid of tripeptides
HS089_RS18540	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HS089_RS18545	COG0693	protein deglycase activity
HS089_RS18550	COG2957	Belongs to the agmatine deiminase family
HS089_RS18555	COG2200	EAL domain
HS089_RS18565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HS089_RS18570	COG0531	amino acid
HS089_RS18575	COG0174	glutamine synthetase
HS089_RS18580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HS089_RS18585	COG1917	Cupin 2, conserved barrel domain protein
HS089_RS18585	COG1396	sequence-specific DNA binding
HS089_RS18590	COG1012	belongs to the aldehyde dehydrogenase family
HS089_RS18595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HS089_RS18610	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HS089_RS18615	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HS089_RS18620	COG1999	signal sequence binding
HS089_RS18625	COG1773	rubredoxin
HS089_RS18630	COG1271	oxidase subunit
HS089_RS18635	COG1294	oxidase, subunit
HS089_RS18665	COG1757	Na H antiporter
HS089_RS18670	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HS089_RS18680	COG0582	viral genome integration into host DNA
HS089_RS18720	COG4372	Transposase
HS089_RS18725	COG3436	PFAM IS66 Orf2 family protein
HS089_RS18770	COG2826	transposase and inactivated derivatives, IS30 family
HS089_RS18790	COG3596	GTP binding
HS089_RS18800	COG2378	regulation of single-species biofilm formation
HS089_RS18830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HS089_RS18845	COG2003	Belongs to the UPF0758 family
HS089_RS18990	COG1783	phage Terminase large subunit
HS089_RS19015	COG3179	chitinase
HS089_RS19085	COG0305	Participates in initiation and elongation during chromosome replication
HS089_RS19115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HS089_RS19145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HS089_RS19155	COG0629	single-stranded DNA binding
HS089_RS19165	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HS089_RS19180	COG0582	viral genome integration into host DNA
HS089_RS19195	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HS089_RS19235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HS089_RS19245	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HS089_RS19270	COG2195	Cleaves the N-terminal amino acid of tripeptides
HS089_RS19295	COG0791	NLP P60 protein
HS089_RS19300	COG3034	peptidoglycan biosynthetic process
HS089_RS19305	COG0121	glutamine amidotransferase
HS089_RS19315	COG1960	acyl-CoA dehydrogenase activity
HS089_RS19320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HS089_RS19330	COG2200	EAL domain
HS089_RS19345	COG3539	Fimbrial protein
HS089_RS19355	COG3121	Chaperone
HS089_RS19360	COG3188	usher protein
HS089_RS19370	COG3539	Fimbrial protein
HS089_RS19375	COG0745	RESPONSE REGULATOR receiver
HS089_RS19390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HS089_RS19400	COG2226	methyltransferase
HS089_RS19410	COG1388	LysM domain
HS089_RS19410	COG0741	lytic transglycosylase activity
HS089_RS19415	COG2226	methyltransferase
HS089_RS19425	COG2814	Major facilitator Superfamily
HS089_RS19430	COG0583	DNA-binding transcription factor activity
HS089_RS19465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HS089_RS19475	COG2011	ABC-type metal ion transport system permease component
HS089_RS19480	COG1464	Belongs to the NlpA lipoprotein family
HS089_RS19490	COG1720	tRNA m6t6A37 methyltransferase activity
HS089_RS19500	COG3015	lipoprotein NlpE involved in copper resistance
HS089_RS19505	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HS089_RS19520	COG4568	rho-dependent transcription termination
HS089_RS19530	COG0346	lactoylglutathione lyase activity
HS089_RS19535	COG1982	Orn Lys Arg decarboxylase major
HS089_RS19570	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HS089_RS19575	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HS089_RS19590	COG0575	Belongs to the CDS family
HS089_RS19600	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HS089_RS19645	COG3835	regulator
HS089_RS19670	COG2860	membrane
HS089_RS19695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HS089_RS19700	COG1120	ATPase activity
HS089_RS19705	COG4774	siderophore transport
HS089_RS19710	COG3539	Fimbrial protein
HS089_RS19715	COG3188	usher protein
HS089_RS19720	COG3121	Chaperone
HS089_RS19730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HS089_RS19735	COG1643	Atp-dependent helicase
HS089_RS19740	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HS089_RS19760	COG0617	tRNA 3'-terminal CCA addition
HS089_RS19765	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HS089_RS19785	COG0726	polysaccharide deacetylase
HS089_RS19790	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS089_RS19795	COG0842	Transport permease protein
HS089_RS19800	COG1131	(ABC) transporter
HS089_RS19805	COG0288	reversible hydration of carbon dioxide
HS089_RS19810	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HS089_RS19840	COG3064	Membrane
HS089_RS19855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HS089_RS19860	COG0508	dehydrogenase complex catalyzes the overall conversion of
HS089_RS19865	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HS089_RS19880	COG2211	Major facilitator Superfamily
HS089_RS19885	COG3940	Belongs to the glycosyl hydrolase 43 family
HS089_RS19890	COG3725	Membrane protein required for beta-lactamase induction
HS089_RS19905	COG4969	Belongs to the N-Me-Phe pilin family
HS089_RS19910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HS089_RS19915	COG1459	type II secretion system
HS089_RS19925	COG0237	dephospho-CoA kinase activity
HS089_RS19940	COG0494	nUDIX hydrolase
HS089_RS19960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HS089_RS19965	COG0849	cell division
HS089_RS19975	COG1181	Belongs to the D-alanine--D-alanine ligase family
HS089_RS19990	COG0772	Belongs to the SEDS family
HS089_RS19995	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HS089_RS20005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HS089_RS20010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HS089_RS20015	COG0768	penicillin binding
HS089_RS20045	COG0028	Belongs to the TPP enzyme family
HS089_RS20080	COG1609	Transcriptional regulator
HS089_RS20090	COG1028	Short-chain dehydrogenase reductase Sdr
HS089_RS20095	COG2814	Major facilitator Superfamily
HS089_RS20115	COG1178	ABC-type Fe3 transport system permease component
HS089_RS20125	COG0586	Pfam SNARE associated Golgi protein
HS089_RS20145	COG0235	Class ii aldolase
HS089_RS20155	COG0417	DNA replication proofreading
HS089_RS20165	COG0564	pseudouridine synthase activity
HS089_RS20175	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HS089_RS20225	COG2271	Major facilitator Superfamily
HS089_RS20235	COG0644	oxidoreductase
HS089_RS20290	COG0505	Belongs to the CarA family
HS089_RS20310	COG1047	Peptidyl-prolyl cis-trans
HS089_RS20325	COG0196	riboflavin kinase activity
HS089_RS20345	COG0583	DNA-binding transcription factor activity
HS089_RS20360	COG0641	radical SAM
HS089_RS20365	COG3119	arylsulfatase activity
HS089_RS20380	COG0443	Heat shock 70 kDa protein
HS089_RS20390	COG4735	regulation of single-species biofilm formation
HS089_RS20395	COG1584	GPR1 FUN34 yaaH family protein
HS089_RS20405	COG0521	Mo-molybdopterin cofactor biosynthetic process
HS089_RS20415	COG1115	amino acid carrier protein
HS089_RS20425	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HS089_RS20435	COG0527	aspartate kinase activity
HS089_RS20435	COG0460	homoserine dehydrogenase
HS089_RS20445	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HS089_RS20455	COG0745	RESPONSE REGULATOR receiver
HS089_RS20460	COG4452	Inner membrane protein CreD
HS089_RS20465	COG2205	protein histidine kinase activity
HS089_RS20470	COG0745	RESPONSE REGULATOR receiver
HS089_RS20475	COG3045	CreA protein
HS089_RS20480	COG2207	Transcriptional regulator
HS089_RS20480	COG3708	Transcriptional regulator
HS089_RS20500	COG0741	lytic transglycosylase activity
HS089_RS20505	COG0488	(ABC) transporter
HS089_RS20520	COG0560	Phosphoserine phosphatase
HS089_RS20525	COG3726	membrane protein affecting hemolysin expression
HS089_RS20555	COG1328	CTP reductase activity
HS089_RS20560	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HS089_RS20565	COG0084	hydrolase, TatD family'
HS089_RS20570	COG4667	esterase of the alpha-beta hydrolase superfamily
HS089_RS20575	COG5487	UPF0391 membrane protein
HS089_RS20580	COG2823	Periplasmic or secreted lipoprotein
HS089_RS20590	COG1011	Hydrolase
HS089_RS20595	COG0456	acetyltransferase
HS089_RS20600	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HS089_RS20630	COG3706	GGDEF domain
HS089_RS20635	COG4114	ferric iron reductase
HS089_RS20640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HS089_RS20645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HS089_RS20650	COG2197	response regulator
HS089_RS20655	COG2197	response regulator
HS089_RS20660	COG2966	Psort location CytoplasmicMembrane, score
HS089_RS20675	COG1484	DNA-dependent DNA replication
HS089_RS20695	COG1063	alcohol dehydrogenase
HS089_RS20700	COG1802	Transcriptional regulator
HS089_RS20705	COG2271	Major facilitator Superfamily
HS089_RS20715	COG0840	transmembrane signaling receptor activity
HS089_RS20720	COG1966	Carbon starvation protein
HS089_RS20725	COG2879	small protein
HS089_RS20730	COG0523	cobalamin synthesis protein
HS089_RS20740	COG1566	PFAM secretion protein HlyD family protein
HS089_RS20750	COG5457	Domain of unknown function (DUF1127)
HS089_RS20755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HS089_RS20760	COG5464	transposase or invertase
HS089_RS20780	COG0626	cystathionine gamma-synthase activity
HS089_RS20785	COG1301	dicarboxylic acid transport
HS089_RS20790	COG0583	DNA-binding transcription factor activity
HS089_RS20795	COG2733	membrane
HS089_RS20805	COG0477	Major facilitator Superfamily
HS089_RS20815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HS089_RS20825	COG2186	Transcriptional regulator
HS089_RS20830	COG0246	Mannitol dehydrogenase
HS089_RS20840	COG2610	gluconate transmembrane transporter activity
HS089_RS20845	COG1556	Lactate utilization protein
HS089_RS20850	COG1139	Iron-sulfur cluster binding protein
HS089_RS20855	COG0247	lactate metabolic process
HS089_RS20860	COG1620	l-lactate permease
HS089_RS20900	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HS089_RS20960	COG0582	viral genome integration into host DNA
HS089_RS20970	COG1064	alcohol dehydrogenase
HS089_RS20975	COG0433	COG0433 Predicted ATPase
HS089_RS20980	COG0795	lipopolysaccharide-transporting ATPase activity
HS089_RS20985	COG0795	lipopolysaccharide-transporting ATPase activity
HS089_RS20995	COG2927	DNA polymerase III (CHI subunit)
HS089_RS21000	COG0525	valine-tRNA ligase activity
HS089_RS21030	COG2731	YhcH YjgK YiaL family protein
HS089_RS21035	COG2235	arginine
HS089_RS21045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HS089_RS21050	COG1288	antiporter activity
HS089_RS21055	COG1438	arginine binding
HS089_RS21100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HS089_RS21115	COG1263	PTS System
HS089_RS21115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS089_RS21120	COG0366	Alpha amylase catalytic
HS089_RS21130	COG1737	Transcriptional regulator
HS089_RS21135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS21140	COG0383	alpha-mannosidase activity
HS089_RS21145	COG0366	Alpha amylase catalytic
HS089_RS21150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS089_RS21150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS21150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS21165	COG2026	Addiction module toxin, RelE StbE family
HS089_RS21170	COG3077	Addiction module antitoxin, RelB DinJ family
HS089_RS21175	COG3711	transcriptional antiterminator
HS089_RS21175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS089_RS21190	COG3964	amidohydrolase
HS089_RS21225	COG0312	modulator of DNA gyrase
HS089_RS21235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HS089_RS21245	COG0840	transmembrane signaling receptor activity
HS089_RS21250	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS089_RS21255	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS089_RS21260	COG1129	ABC transporter
HS089_RS21265	COG1879	ABC-type sugar transport system periplasmic component
HS089_RS21275	COG2105	PFAM AIG2 family protein
HS089_RS21280	COG2911	Protein conserved in bacteria
HS089_RS21285	COG0729	surface antigen
HS089_RS21295	COG1253	flavin adenine dinucleotide binding
HS089_RS21305	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HS089_RS21310	COG1218	3'(2'),5'-bisphosphate nucleotidase
HS089_RS21320	COG1733	regulation of RNA biosynthetic process
HS089_RS21325	COG0702	epimerase
HS089_RS21335	COG0697	spore germination
HS089_RS21340	COG0840	transmembrane signaling receptor activity
HS089_RS21350	COG1113	amino acid transport
HS089_RS21355	COG0545	Peptidyl-prolyl cis-trans isomerase
HS089_RS21360	COG3061	Opacity-associated protein A
HS089_RS21375	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HS089_RS21390	COG0730	response to heat
HS089_RS21440	COG1073	alpha beta
HS089_RS21445	COG3650	response to hydrogen peroxide
HS089_RS21455	COG1960	acyl-CoA dehydrogenase activity
HS089_RS21460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HS089_RS21465	COG0557	exoribonuclease II activity
HS089_RS21480	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HS089_RS21485	COG0330	HflC and HflK could
HS089_RS21490	COG0330	HflC and HflK could
HS089_RS21495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HS089_RS21500	COG1923	regulation of RNA biosynthetic process
HS089_RS21515	COG0860	N-Acetylmuramoyl-L-alanine amidase
HS089_RS21520	COG0802	atpase or kinase
HS089_RS21525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HS089_RS21525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HS089_RS21530	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HS089_RS21565	COG3264	Mechanosensitive ion channel
HS089_RS21565	COG1511	domain protein
HS089_RS21580	COG1053	succinate dehydrogenase
HS089_RS21585	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HS089_RS21640	COG1509	lysine 2,3-aminomutase activity
HS089_RS21665	COG0531	amino acid
HS089_RS21670	COG3030	protein affecting phage T7 exclusion by the F plasmid
HS089_RS21675	COG1027	Aspartate ammonia-lyase
HS089_RS21680	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HS089_RS21695	COG1309	transcriptional regulator
HS089_RS21705	COG0318	PFAM AMP-dependent synthetase and ligase
HS089_RS21735	COG3290	protein histidine kinase activity
HS089_RS21740	COG4565	transcriptional regulatory protein
HS089_RS21745	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HS089_RS21750	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HS089_RS21750	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HS089_RS21755	COG3647	Membrane
HS089_RS21765	COG2211	Major facilitator Superfamily
HS089_RS21770	COG1486	melibiose metabolic process
HS089_RS21775	COG2169	Transcriptional regulator
HS089_RS21780	COG1982	Orn Lys Arg decarboxylase major
HS089_RS21785	COG2207	Transcriptional regulator
HS089_RS21790	COG0531	amino acid
HS089_RS21830	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HS089_RS21835	COG2824	Alkylphosphonate utilization operon protein PhnA
HS089_RS21840	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HS089_RS21845	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HS089_RS21850	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HS089_RS21855	COG3639	organic phosphonate transmembrane transporter activity
HS089_RS21860	COG2188	Transcriptional regulator
HS089_RS21865	COG3624	Phosphonate C-P lyase system protein PhnG
HS089_RS21870	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HS089_RS21875	COG3626	phosphonate metabolism
HS089_RS21880	COG3627	carbon phosphorus lyase activity
HS089_RS21885	COG4107	phosphonate C-P lyase system protein PhnK
HS089_RS21890	COG4778	phosphonate C-P lyase system protein PhnL
HS089_RS21895	COG3454	Phosphonate metabolism
HS089_RS21905	COG0456	acetyltransferase
HS089_RS21910	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HS089_RS21925	COG1129	ABC transporter
HS089_RS21930	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS089_RS21960	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HS089_RS21970	COG1566	PFAM secretion protein HlyD family protein
HS089_RS21975	COG1289	transmembrane transporter activity
HS089_RS21980	COG1538	Outer membrane efflux protein
HS089_RS21990	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HS089_RS21995	COG1301	dicarboxylic acid transport
HS089_RS22000	COG4235	cytochrome complex assembly
HS089_RS22005	COG3088	subunit of a heme lyase
HS089_RS22010	COG1138	Cytochrome C-type biogenesis protein
HS089_RS22015	COG3301	Polysulphide reductase, NrfD
HS089_RS22020	COG0437	4 iron, 4 sulfur cluster binding
HS089_RS22025	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HS089_RS22040	COG3162	membrane
HS089_RS22050	COG1346	cytolysis
HS089_RS22055	COG1380	Effector of murein hydrolase LrgA
HS089_RS22060	COG0583	DNA-binding transcription factor activity
HS089_RS22065	COG1943	Transposase
HS089_RS22070	COG0025	NhaP-type Na H and K H
HS089_RS22075	COG2252	PERMEase
HS089_RS22080	COG0789	Transcriptional regulator
HS089_RS22090	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HS089_RS22100	COG0629	single-stranded DNA binding
HS089_RS22105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HS089_RS22110	COG2315	Protein conserved in bacteria
HS089_RS22115	COG3700	Belongs to the class B bacterial acid phosphatase family
HS089_RS22120	COG1448	Aminotransferase
HS089_RS22130	COG0305	Participates in initiation and elongation during chromosome replication
HS089_RS22145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HS089_RS22155	COG0735	belongs to the Fur family
HS089_RS22160	COG3237	CsbD-like
HS089_RS22165	COG0534	Mate efflux family protein
HS089_RS22175	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HS089_RS22210	COG2182	Extracellular solute-binding protein
HS089_RS22225	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HS089_RS22230	COG1757	Na H antiporter
HS089_RS22235	COG3223	Belongs to the PsiE family
HS089_RS22240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HS089_RS22245	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HS089_RS22270	COG0527	aspartate kinase activity
HS089_RS22275	COG3541	Predicted nucleotidyltransferase
HS089_RS22285	COG4650	regulator
HS089_RS22305	COG0561	phosphatase activity
HS089_RS22320	COG1187	pseudouridine synthase activity
HS089_RS22360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HS089_RS22375	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HS089_RS22400	COG0646	methionine synthase
HS089_RS22400	COG1410	methionine synthase
HS089_RS22410	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HS089_RS22420	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HS089_RS22430	COG0456	acetyltransferase
HS089_RS22455	COG0151	Belongs to the GarS family
HS089_RS22465	COG4191	Histidine kinase
HS089_RS22525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HS089_RS22530	COG2104	thiamine diphosphate biosynthetic process
HS089_RS22545	COG1278	Cold shock
HS089_RS22555	COG1447	Phosphotransferase system cellobiose-specific component IIA
HS089_RS22590	COG0250	Participates in transcription elongation, termination and antitermination
HS089_RS22635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HS089_RS22695	COG0583	DNA-binding transcription factor activity
HS089_RS22730	COG2207	Transcriptional regulator
HS089_RS22740	COG0371	Dehydrogenase
HS089_RS22750	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HS089_RS22755	COG0583	DNA-binding transcription factor activity
HS089_RS22765	COG0737	Belongs to the 5'-nucleotidase family
HS089_RS22775	COG0527	aspartate kinase activity
HS089_RS22775	COG0460	homoserine dehydrogenase
HS089_RS22780	COG0626	cystathionine gamma-synthase activity
HS089_RS22790	COG2211	Major facilitator Superfamily
HS089_RS22805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HS089_RS22810	COG1609	Transcriptional regulator
HS089_RS22815	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HS089_RS22830	COG1575	Belongs to the MenA family. Type 1 subfamily
HS089_RS22845	COG3074	FtsZ-dependent cytokinesis
HS089_RS22850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HS089_RS22860	COG1494	fructose-1,6-bisphosphatase
HS089_RS22870	COG3152	Membrane
HS089_RS22885	COG0471	metal ion transport
HS089_RS22915	COG3678	ATP-independent chaperone mediated protein folding
HS089_RS22920	COG0745	RESPONSE REGULATOR receiver
HS089_RS22925	COG2205	protein histidine kinase activity
HS089_RS22930	COG2258	MOSC domain
HS089_RS22935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HS089_RS22980	COG1454	alcohol dehydrogenase
HS089_RS22995	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HS089_RS23005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS089_RS23010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS23010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS089_RS23015	COG1363	Peptidase, m42
HS089_RS23020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS089_RS23020	COG3711	transcriptional antiterminator
HS089_RS23050	COG0437	4 iron, 4 sulfur cluster binding
HS089_RS23055	COG2864	formate dehydrogenase
HS089_RS23070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HS089_RS23080	COG0456	acetyltransferase
HS089_RS23085	COG1490	D-aminoacyl-tRNA deacylase activity
HS089_RS23095	COG1011	Hydrolase
HS089_RS23100	COG1349	DNA-binding transcription factor activity
HS089_RS23105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS089_RS23115	COG3684	Belongs to the aldolase LacD family
HS089_RS23125	COG2017	converts alpha-aldose to the beta-anomer
HS089_RS23130	COG1501	Belongs to the glycosyl hydrolase 31 family
HS089_RS23160	COG3852	Histidine kinase
HS089_RS23165	COG2204	response regulator
HS089_RS23175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HS089_RS23195	COG0204	Acyl-transferase
HS089_RS23210	COG3084	Protein conserved in bacteria
HS089_RS23215	COG0746	molybdenum cofactor guanylyltransferase activity
HS089_RS23220	COG1763	Mo-molybdopterin cofactor biosynthetic process
HS089_RS23260	COG1739	Uncharacterized protein family UPF0029
HS089_RS23280	COG1609	Transcriptional regulator
HS089_RS23285	COG1940	carbohydrate kinase activity
HS089_RS23310	COG0805	protein transport
HS089_RS23360	COG0583	DNA-binding transcription factor activity
HS089_RS23365	COG0697	spore germination
HS089_RS23370	COG0561	phosphatase activity
HS089_RS23375	COG2267	carboxylic ester hydrolase activity
HS089_RS23380	COG1280	lysine exporter protein (LysE YggA)
HS089_RS23390	COG1280	lysine exporter protein (LysE YggA)
HS089_RS23425	COG1011	Hydrolase
HS089_RS23470	COG2959	enzyme of heme biosynthesis
HS089_RS23475	COG3071	HemY protein
HS089_RS23520	COG2244	polysaccharide biosynthetic process
HS089_RS23525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HS089_RS23530	COG0456	acetyltransferase
HS089_RS23535	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HS089_RS23555	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HS089_RS23565	COG3118	belongs to the thioredoxin family
HS089_RS23585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HS089_RS23605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HS089_RS23615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HS089_RS23620	COG3978	acetolactate synthase activity
HS089_RS23640	COG3085	chromosome segregation
HS089_RS23680	COG2186	Transcriptional regulator
HS089_RS23685	COG0477	Major facilitator Superfamily
HS089_RS23690	COG1609	Transcriptional regulator
HS089_RS23695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS089_RS23700	COG1879	ABC-type sugar transport system periplasmic component
HS089_RS23705	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS089_RS23715	COG1869	D-ribose catabolic process
HS089_RS23740	COG1522	sequence-specific DNA binding
HS089_RS23745	COG0716	FMN binding
HS089_RS23760	COG3312	ion transport
HS089_RS23785	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HS089_RS23795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HS089_RS23800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HS089_RS23890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HS089_RS23895	COG0573	inorganic phosphate transmembrane transporter activity
HS089_RS23900	COG0581	inorganic phosphate transmembrane transporter activity
HS089_RS23910	COG0704	Plays a role in the regulation of phosphate uptake
HS089_RS23915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HS089_RS23920	COG2252	PERMEase
HS089_RS23925	COG0431	NADPH-dependent FMN reductase
HS089_RS23930	COG2091	lysine biosynthetic process via aminoadipic acid
HS089_RS23965	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HS089_RS23990	COG0659	secondary active sulfate transmembrane transporter activity
HS089_RS23995	COG0589	response to stress
HS089_RS24030	COG1136	(ABC) transporter
HS089_RS24045	COG1309	transcriptional regulator
HS089_RS24200	COG1660	Displays ATPase and GTPase activities
HS089_RS24215	COG3173	Aminoglycoside phosphotransferase
HS089_RS24240	COG1695	Transcriptional regulator
HS089_RS24320	COG0789	Transcriptional regulator
HS089_RS24370	COG1609	Transcriptional regulator
HS089_RS24390	COG1129	ABC transporter
HS089_RS24395	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS089_RS24680	COG0629	single-stranded DNA binding
HS089_RS24730	COG2135	peptidase activity
HS089_RS24765	COG1121	(ABC) transporter
HS089_RS24795	COG2433	Pfam Transposase IS66
HS089_RS24800	COG3436	PFAM IS66 Orf2 family protein
HS089_RS24810	COG2826	transposase and inactivated derivatives, IS30 family
HS089_RS24865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HS089_RS24900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HS089_RS24920	COG3451	type IV secretory pathway VirB4
HS089_RS24945	COG3736	Type IV secretory pathway, component VirB8
HS089_RS24955	COG2948	multi-organism process
HS089_RS24960	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
HS089_RS24985	COG4372	Transposase
HS089_RS24990	COG3436	PFAM IS66 Orf2 family protein
HS089_RS25045	COG3039	Transposase
HS089_RS25085	COG3093	addiction module antidote protein HigA
HS089_RS25135	COG1216	Glycosyl transferase, family 2
HS089_RS25140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HS089_RS25155	COG1215	transferase activity, transferring glycosyl groups
HS089_RS25160	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HS089_RS25165	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HS089_RS25195	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HS089_RS25240	COG0741	lytic transglycosylase activity
HS089_RS25435	COG4973	Belongs to the 'phage' integrase family. XerC subfamily