locus-tag	class	description
F3113_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F3113_RS00010	COG0592	DNA-directed DNA polymerase activity
F3113_RS00025	COG0561	phosphatase activity
F3113_RS00035	COG0823	Involved in the tonB-independent uptake of proteins
F3113_RS00040	COG5645	(Lipo)protein
F3113_RS00060	COG2149	membrane
F3113_RS00070	COG0641	radical SAM
F3113_RS00080	COG2610	gluconate transmembrane transporter activity
F3113_RS00085	COG0583	DNA-binding transcription factor activity
F3113_RS00095	COG2814	Major facilitator Superfamily
F3113_RS00115	COG0028	Belongs to the TPP enzyme family
F3113_RS00120	COG0440	acetolactate synthase activity
F3113_RS00125	COG1349	DNA-binding transcription factor activity
F3113_RS00135	COG0738	Major facilitator superfamily
F3113_RS00145	COG2197	response regulator
F3113_RS00175	COG3620	sequence-specific DNA binding
F3113_RS00185	COG2723	6-phospho-beta-galactosidase activity
F3113_RS00210	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3113_RS00210	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3113_RS00215	COG3715	PTS system
F3113_RS00220	COG3716	PTS system mannose fructose sorbose family IID component
F3113_RS00235	COG5464	transposase or invertase
F3113_RS00240	COG1464	Belongs to the NlpA lipoprotein family
F3113_RS00245	COG0697	spore germination
F3113_RS00255	COG0604	alcohol dehydrogenase
F3113_RS00260	COG0583	DNA-binding transcription factor activity
F3113_RS00280	COG2771	luxR family
F3113_RS00340	COG2003	Belongs to the UPF0758 family
F3113_RS00400	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
F3113_RS00405	COG0732	type I restriction modification DNA specificity domain
F3113_RS00415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
F3113_RS00450	COG0582	viral genome integration into host DNA
F3113_RS00455	COG0582	viral genome integration into host DNA
F3113_RS00465	COG2211	Major facilitator Superfamily
F3113_RS00470	COG1501	Belongs to the glycosyl hydrolase 31 family
F3113_RS00475	COG3711	transcriptional antiterminator
F3113_RS00480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS00480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS00480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3113_RS00485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS00490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS00490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS00500	COG0191	fructose-bisphosphate aldolase activity
F3113_RS00510	COG2982	Protein involved in outer membrane biogenesis
F3113_RS00515	COG2233	PERMEase
F3113_RS00520	COG0786	glutamate:sodium symporter activity
F3113_RS00525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F3113_RS00530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3113_RS00535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F3113_RS00555	COG2860	membrane
F3113_RS00560	COG1561	YicC-like family, N-terminal region
F3113_RS00585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F3113_RS00600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F3113_RS00615	COG1519	Transferase
F3113_RS00620	COG0438	transferase activity, transferring glycosyl groups
F3113_RS00625	COG0515	serine threonine protein kinase
F3113_RS00630	COG1442	glycosyl transferase family 8
F3113_RS00655	COG3307	-O-antigen
F3113_RS00665	COG0859	PFAM glycosyl transferase family 9
F3113_RS00675	COG0156	8-amino-7-oxononanoate synthase activity
F3113_RS00685	COG1216	Glycosyl transferase, family 2
F3113_RS00690	COG2861	carbohydrate metabolic process
F3113_RS00695	COG4942	peptidase
F3113_RS00705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3113_RS00710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F3113_RS00725	COG1045	serine acetyltransferase
F3113_RS00730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F3113_RS00735	COG2271	Major facilitator Superfamily
F3113_RS00745	COG2186	Transcriptional regulator
F3113_RS00765	COG3722	fumarate hydratase activity
F3113_RS00775	COG2213	PTS system mannitol-specific
F3113_RS00775	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3113_RS00785	COG1566	PFAM secretion protein HlyD family protein
F3113_RS00790	COG0625	glutathione transferase activity
F3113_RS00800	COG3276	selenocysteine insertion sequence binding
F3113_RS00805	COG1454	alcohol dehydrogenase
F3113_RS00810	COG1012	belongs to the aldehyde dehydrogenase family
F3113_RS00820	COG1566	PFAM secretion protein HlyD family protein
F3113_RS00830	COG0583	DNA-binding transcription factor activity
F3113_RS00835	COG3713	MltA-interacting MipA family protein
F3113_RS00845	COG2211	Major facilitator Superfamily
F3113_RS00850	COG4977	sequence-specific DNA binding
F3113_RS00850	COG1917	Cupin 2, conserved barrel domain protein
F3113_RS00855	COG0235	Class ii aldolase
F3113_RS00860	COG3623	hexulose-6-phosphate isomerase
F3113_RS00865	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
F3113_RS00870	COG1070	Carbohydrate kinase
F3113_RS00875	COG2271	Major facilitator Superfamily
F3113_RS00885	COG2731	YhcH YjgK YiaL family protein
F3113_RS00895	COG1414	Transcriptional regulator
F3113_RS00900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3113_RS00905	COG3977	Valine--pyruvate aminotransferase
F3113_RS00910	COG0366	Alpha amylase catalytic
F3113_RS00915	COG2992	FlgJ-related protein
F3113_RS00920	COG2207	Transcriptional regulator
F3113_RS00920	COG1609	Transcriptional regulator
F3113_RS00930	COG1070	Carbohydrate kinase
F3113_RS00935	COG4682	membrane
F3113_RS00940	COG3274	enterobacterial common antigen metabolic process
F3113_RS00965	COG1278	Cold shock
F3113_RS00970	COG2944	sequence-specific DNA binding
F3113_RS00985	COG2814	Major facilitator Superfamily
F3113_RS00990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3113_RS01000	COG1609	Transcriptional regulator
F3113_RS01005	COG2885	chlorophyll binding
F3113_RS01010	COG0243	molybdopterin cofactor binding
F3113_RS01015	COG0456	acetyltransferase
F3113_RS01020	COG2818	Glycosylase
F3113_RS01025	COG5571	outer membrane autotransporter
F3113_RS01030	COG2223	nitrite transmembrane transporter activity
F3113_RS01055	COG0747	negative chemotaxis
F3113_RS01060	COG0601	transmembrane transport
F3113_RS01065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3113_RS01070	COG0444	Belongs to the ABC transporter superfamily
F3113_RS01075	COG4608	Belongs to the ABC transporter superfamily
F3113_RS01080	COG2204	response regulator
F3113_RS01085	COG0814	amino acid
F3113_RS01090	COG0626	cystathionine gamma-synthase activity
F3113_RS01100	COG2199	diguanylate cyclase activity
F3113_RS01100	COG2200	EAL domain
F3113_RS01115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3113_RS01120	COG2200	EAL domain
F3113_RS01125	COG2982	Protein involved in outer membrane biogenesis
F3113_RS01130	COG0477	Major facilitator Superfamily
F3113_RS01135	COG1295	ribonuclease BN
F3113_RS01140	COG0583	DNA-binding transcription factor activity
F3113_RS01145	COG1028	Short-chain dehydrogenase reductase Sdr
F3113_RS01155	COG2200	EAL domain
F3113_RS01160	COG2197	response regulator
F3113_RS01170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3113_RS01185	COG1858	cytochrome C peroxidase
F3113_RS01195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3113_RS01200	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F3113_RS01205	COG0339	signal peptide processing
F3113_RS01220	COG1959	2 iron, 2 sulfur cluster binding
F3113_RS01230	COG0589	response to stress
F3113_RS01240	COG0306	phosphate transporter
F3113_RS01245	COG2081	HI0933 family
F3113_RS01315	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3113_RS01345	COG0739	heme binding
F3113_RS01355	COG2132	Multicopper oxidase
F3113_RS01360	COG3667	copper resistance
F3113_RS01365	COG2372	response to copper ion
F3113_RS01370	COG1276	copper resistance
F3113_RS01375	COG0745	RESPONSE REGULATOR receiver
F3113_RS01380	COG2205	protein histidine kinase activity
F3113_RS01395	COG3436	PFAM IS66 Orf2 family protein
F3113_RS01400	COG4372	Transposase
F3113_RS01405	COG2239	Acts as a magnesium transporter
F3113_RS01410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3113_RS01415	COG0842	Transport permease protein
F3113_RS01415	COG1129	ABC transporter
F3113_RS01420	COG0842	Transport permease protein
F3113_RS01440	COG2091	lysine biosynthetic process via aminoadipic acid
F3113_RS01445	COG0628	permease
F3113_RS01450	COG0477	Major facilitator Superfamily
F3113_RS01460	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F3113_RS01475	COG3714	YhhN family
F3113_RS01500	COG3776	membrane
F3113_RS01505	COG0742	ribosomal rna small subunit methyltransferase
F3113_RS01510	COG0552	protein localization to endoplasmic reticulum
F3113_RS01515	COG2884	Cell division ATP-binding protein ftsE
F3113_RS01520	COG2177	Part of the ABC transporter FtsEX involved in
F3113_RS01545	COG0683	leucine binding
F3113_RS01555	COG4177	L-phenylalanine transmembrane transporter activity
F3113_RS01560	COG0411	ABC transporter
F3113_RS01595	COG0584	glycerophosphoryl diester phosphodiesterase
F3113_RS01605	COG0405	Gamma-glutamyltransferase
F3113_RS01610	COG1735	metal-dependent hydrolase with the TIM-barrel fold
F3113_RS01625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3113_RS01635	COG1247	-acetyltransferase
F3113_RS01640	COG0673	inositol 2-dehydrogenase activity
F3113_RS01645	COG1741	Belongs to the pirin family
F3113_RS01650	COG1609	Transcriptional regulator
F3113_RS01655	COG3265	gluconokinase activity
F3113_RS01660	COG2610	gluconate transmembrane transporter activity
F3113_RS01675	COG2095	MarC family integral membrane protein
F3113_RS01680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F3113_RS01705	COG0058	SHG alpha-glucan phosphorylase activity
F3113_RS01710	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F3113_RS01725	COG1349	DNA-binding transcription factor activity
F3113_RS01735	COG0058	SHG alpha-glucan phosphorylase activity
F3113_RS01740	COG1640	4-alpha-glucanotransferase
F3113_RS01745	COG2610	gluconate transmembrane transporter activity
F3113_RS01755	COG1040	competence protein
F3113_RS01780	COG1918	ferrous iron import across plasma membrane
F3113_RS01785	COG2183	response to ionizing radiation
F3113_RS01790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3113_RS01820	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F3113_RS01830	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F3113_RS01835	COG1011	Hydrolase
F3113_RS01845	COG0494	nUDIX hydrolase
F3113_RS01850	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F3113_RS01855	COG4972	Pilus assembly protein
F3113_RS01860	COG3166	PFAM Fimbrial assembly family protein
F3113_RS01875	COG4796	Type ii and iii secretion system protein
F3113_RS01890	COG3266	domain, Protein
F3113_RS01895	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F3113_RS01900	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F3113_RS01910	COG0180	Tryptophanyl-tRNA synthetase
F3113_RS01915	COG2188	Transcriptional regulator
F3113_RS01925	COG3457	Alanine racemase
F3113_RS01930	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
F3113_RS01935	COG1735	metal-dependent hydrolase with the TIM-barrel fold
F3113_RS01950	COG0626	cystathionine gamma-synthase activity
F3113_RS01970	COG2146	nitrite reductase [NAD(P)H] activity
F3113_RS01975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3113_RS02000	COG0512	Glutamine amidotransferase of anthranilate synthase
F3113_RS02005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3113_RS02010	COG1289	transmembrane transporter activity
F3113_RS02020	COG1765	OsmC-like protein
F3113_RS02025	COG3954	Phosphoribulokinase
F3113_RS02035	COG0429	hydrolase of the alpha beta-hydrolase fold
F3113_RS02045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F3113_RS02055	COG0488	(ABC) transporter
F3113_RS02070	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
F3113_RS02075	COG1047	Peptidyl-prolyl cis-trans
F3113_RS02085	COG0545	Peptidyl-prolyl cis-trans isomerase
F3113_RS02090	COG2964	Protein conserved in bacteria
F3113_RS02115	COG0049	tRNA binding
F3113_RS02145	COG0051	transcription antitermination factor activity, RNA binding
F3113_RS02155	COG0088	Forms part of the polypeptide exit tunnel
F3113_RS02170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F3113_RS02245	COG0200	Binds to the 23S rRNA
F3113_RS02250	COG0201	protein transport
F3113_RS02265	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F3113_RS02290	COG0789	Transcriptional regulator
F3113_RS02295	COG3036	rescue of stalled ribosome
F3113_RS02305	COG0569	domain protein
F3113_RS02325	COG0758	DNA mediated transformation
F3113_RS02335	COG0551	DNA topoisomerase type I activity
F3113_RS02355	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F3113_RS02395	COG1126	abc transporter atp-binding protein
F3113_RS02400	COG0765	amino acid transport
F3113_RS02405	COG4597	amino acid ABC transporter
F3113_RS02410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3113_RS02420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3113_RS02425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3113_RS02430	COG1309	transcriptional regulator
F3113_RS02440	COG2189	Belongs to the N(4) N(6)-methyltransferase family
F3113_RS02525	COG4145	pantothenate transmembrane transporter activity
F3113_RS02530	COG3924	membrane
F3113_RS02535	COG0439	Biotin carboxylase
F3113_RS02540	COG0511	ligase activity, forming carbon-carbon bonds
F3113_RS02555	COG0604	alcohol dehydrogenase
F3113_RS02560	COG2200	EAL domain
F3113_RS02560	COG2199	diguanylate cyclase activity
F3113_RS02570	COG1077	Cell shape determining protein MreB Mrl
F3113_RS02575	COG1792	Involved in formation and maintenance of cell shape
F3113_RS02580	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F3113_RS02595	COG3164	Protein of unknown function
F3113_RS02600	COG0312	modulator of DNA gyrase
F3113_RS02605	COG0583	DNA-binding transcription factor activity
F3113_RS02625	COG2732	(Barnase) inhibitor
F3113_RS02645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3113_RS02650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3113_RS02655	COG3105	Protein conserved in bacteria
F3113_RS02660	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F3113_RS02675	COG0625	glutathione transferase activity
F3113_RS02680	COG2969	positive regulation of protein catabolic process
F3113_RS02685	COG3069	C4-dicarboxylate transmembrane transporter activity
F3113_RS02710	COG2731	YhcH YjgK YiaL family protein
F3113_RS02715	COG0402	S-adenosylhomocysteine deaminase activity
F3113_RS02720	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F3113_RS02725	COG4804	nuclease activity
F3113_RS02730	COG0493	'glutamate synthase
F3113_RS02735	COG0067	glutamate synthase
F3113_RS02735	COG0069	glutamate synthase activity
F3113_RS02735	COG0070	glutamate synthase
F3113_RS02740	COG1242	4 iron, 4 sulfur cluster binding
F3113_RS02745	COG5002	protein histidine kinase activity
F3113_RS02745	COG0784	Response regulator, receiver
F3113_RS02745	COG2198	Histidine kinase
F3113_RS02750	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
F3113_RS02760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3113_RS02775	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F3113_RS02785	COG1137	ATPase activity
F3113_RS02790	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F3113_RS02795	COG3117	lipopolysaccharide transmembrane transporter activity
F3113_RS02800	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F3113_RS02810	COG0530	calcium, potassium:sodium antiporter activity
F3113_RS02815	COG1127	ABC transporter
F3113_RS02820	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F3113_RS02825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F3113_RS02830	COG2854	intermembrane phospholipid transfer
F3113_RS02835	COG3113	response to antibiotic
F3113_RS02840	COG5007	Belongs to the BolA IbaG family
F3113_RS02850	COG3423	Transcriptional regulator
F3113_RS02855	COG0142	geranyltranstransferase activity
F3113_RS02860	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F3113_RS02865	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F3113_RS02870	COG0697	spore germination
F3113_RS02880	COG2027	D-alanyl-D-alanine carboxypeptidase
F3113_RS02890	COG1534	Rna-binding protein
F3113_RS02900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3113_RS02905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F3113_RS02915	COG3069	C4-dicarboxylate transmembrane transporter activity
F3113_RS02920	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F3113_RS02925	COG0583	DNA-binding transcription factor activity
F3113_RS02930	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3113_RS02955	COG0195	Participates in both transcription termination and antitermination
F3113_RS02960	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F3113_RS02965	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F3113_RS02995	COG0513	Belongs to the DEAD box helicase family
F3113_RS03000	COG0814	amino acid
F3113_RS03005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3113_RS03010	COG0826	peptidase U32
F3113_RS03015	COG0826	peptidase U32
F3113_RS03020	COG3154	lipid carrier protein
F3113_RS03025	COG3153	acetyltransferase
F3113_RS03040	COG0702	epimerase
F3113_RS03045	COG2823	Periplasmic or secreted lipoprotein
F3113_RS03065	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F3113_RS03075	COG2222	sugar isomerase
F3113_RS03080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F3113_RS03085	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3113_RS03090	COG3716	PTS system mannose fructose sorbose family IID component
F3113_RS03100	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3113_RS03110	COG1349	DNA-binding transcription factor activity
F3113_RS03115	COG1349	DNA-binding transcription factor activity
F3113_RS03120	COG1940	carbohydrate kinase activity
F3113_RS03125	COG0673	inositol 2-dehydrogenase activity
F3113_RS03130	COG3842	ATPase activity
F3113_RS03135	COG0395	ABC-type sugar transport system, permease component
F3113_RS03140	COG1175	transmembrane transport
F3113_RS03150	COG2721	sulfolactate sulfo-lyase activity
F3113_RS03155	COG2271	Major facilitator Superfamily
F3113_RS03165	COG2084	Dehydrogenase
F3113_RS03170	COG1929	Belongs to the glycerate kinase type-1 family
F3113_RS03210	COG0583	DNA-binding transcription factor activity
F3113_RS03230	COG1882	Formate acetyltransferase
F3113_RS03235	COG0251	oxidation-reduction process
F3113_RS03240	COG1760	l-serine dehydratase
F3113_RS03245	COG0814	amino acid
F3113_RS03260	COG1741	Belongs to the pirin family
F3113_RS03265	COG0583	DNA-binding transcription factor activity
F3113_RS03270	COG3152	Membrane
F3113_RS03275	COG0435	Glutathione S-transferase
F3113_RS03280	COG2259	Doxx family
F3113_RS03290	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
F3113_RS03295	COG4575	ribosome binding
F3113_RS03300	COG1422	Protein of unknown function (DUF1090)
F3113_RS03310	COG0586	Pfam SNARE associated Golgi protein
F3113_RS03315	COG2186	Transcriptional regulator
F3113_RS03320	COG2271	Major facilitator Superfamily
F3113_RS03330	COG2721	sulfolactate sulfo-lyase activity
F3113_RS03350	COG0673	inositol 2-dehydrogenase activity
F3113_RS03355	COG1451	nucleotide metabolic process
F3113_RS03365	COG1902	pentaerythritol trinitrate reductase activity
F3113_RS03365	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3113_RS03370	COG3408	Glycogen debranching enzyme
F3113_RS03370	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
F3113_RS03380	COG0531	amino acid
F3113_RS03385	COG2731	YhcH YjgK YiaL family protein
F3113_RS03390	COG3250	beta-galactosidase activity
F3113_RS03395	COG1609	Transcriptional regulator
F3113_RS03400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3113_RS03410	COG0840	transmembrane signaling receptor activity
F3113_RS03415	COG1695	Transcriptional regulator
F3113_RS03420	COG2375	cellular response to nickel ion
F3113_RS03430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3113_RS03500	COG4974	Belongs to the 'phage' integrase family
F3113_RS03535	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F3113_RS03565	COG4695	Portal protein
F3113_RS03715	COG4771	TonB-dependent receptor
F3113_RS03720	COG3391	amine dehydrogenase activity
F3113_RS03730	COG0358	DNA primase activity
F3113_RS03735	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F3113_RS03740	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F3113_RS03745	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F3113_RS03755	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
F3113_RS03785	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F3113_RS03790	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F3113_RS03805	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F3113_RS03820	COG4991	sh3 domain protein
F3113_RS03825	COG3025	triphosphatase activity
F3113_RS03840	COG2268	Band 7 protein
F3113_RS03845	COG1585	Membrane protein implicated in regulation of membrane protease activity
F3113_RS03885	COG3384	dioxygenase
F3113_RS03890	COG0754	glutathionylspermidine amidase activity
F3113_RS03905	COG0494	nUDIX hydrolase
F3113_RS03910	COG3151	Protein conserved in bacteria
F3113_RS03915	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F3113_RS03920	COG3150	esterase
F3113_RS03925	COG0187	DNA topoisomerase II activity
F3113_RS03930	COG4977	sequence-specific DNA binding
F3113_RS03930	COG1917	Cupin 2, conserved barrel domain protein
F3113_RS03940	COG2211	Major facilitator Superfamily
F3113_RS03945	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F3113_RS03950	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F3113_RS03955	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3113_RS03970	COG3111	PFAM Bacterial OB fold (BOF) protein
F3113_RS03990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F3113_RS04005	COG0471	metal ion transport
F3113_RS04010	COG0656	L-ascorbic acid biosynthetic process
F3113_RS04015	COG1979	alcohol dehydrogenase
F3113_RS04020	COG2207	Transcriptional regulator
F3113_RS04025	COG0586	Pfam SNARE associated Golgi protein
F3113_RS04030	COG0626	cystathionine gamma-synthase activity
F3113_RS04040	COG0848	biopolymer transport protein
F3113_RS04060	COG0667	Aldo Keto reductase
F3113_RS04070	COG0840	transmembrane signaling receptor activity
F3113_RS04080	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
F3113_RS04085	COG0437	4 iron, 4 sulfur cluster binding
F3113_RS04090	COG5557	Pfam Polysulphide reductase, NrfD
F3113_RS04095	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
F3113_RS04100	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F3113_RS04105	COG1773	rubredoxin
F3113_RS04115	COG0298	carbon dioxide binding
F3113_RS04120	COG0625	glutathione transferase activity
F3113_RS04125	COG0243	molybdopterin cofactor binding
F3113_RS04130	COG0754	glutathionylspermidine amidase activity
F3113_RS04140	COG1811	Na channel or pump
F3113_RS04145	COG1982	Orn Lys Arg decarboxylase major
F3113_RS04150	COG2211	Major facilitator Superfamily
F3113_RS04165	COG1194	a g-specific adenine glycosylase
F3113_RS04175	COG3171	Protein conserved in bacteria
F3113_RS04185	COG0252	asparaginase activity
F3113_RS04190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3113_RS04205	COG0762	integral membrane protein
F3113_RS04210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F3113_RS04215	COG2805	Type II/IV secretion system protein
F3113_RS04230	COG0189	ligase activity
F3113_RS04235	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F3113_RS04240	COG2356	endonuclease I
F3113_RS04245	COG3091	SprT-like family
F3113_RS04250	COG2814	Major facilitator Superfamily
F3113_RS04270	COG1166	arginine decarboxylase activity
F3113_RS04280	COG0501	Belongs to the peptidase M48B family
F3113_RS04285	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F3113_RS04290	COG1122	ATPase activity
F3113_RS04295	COG1122	ATPase activity
F3113_RS04325	COG0191	fructose-bisphosphate aldolase activity
F3113_RS04385	COG2003	Belongs to the UPF0758 family
F3113_RS04415	COG5489	Protein of unknown function (DUF736)
F3113_RS04445	COG1192	Involved in chromosome partitioning
F3113_RS04460	COG4959	Type IV secretory pathway protease TraF
F3113_RS04485	COG2076	Multidrug Resistance protein
F3113_RS04510	COG0583	DNA-binding transcription factor activity
F3113_RS04530	COG4962	Type ii secretion system protein e
F3113_RS04535	COG3838	Conjugal transfer protein Trbc
F3113_RS04545	COG3451	type IV secretory pathway VirB4
F3113_RS04560	COG3846	protein secretion by the type IV secretion system
F3113_RS04575	COG2948	multi-organism process
F3113_RS04585	COG0668	transmembrane transport
F3113_RS04590	COG1279	arginine transmembrane transporter activity
F3113_RS04595	COG2968	Membrane
F3113_RS04600	COG0583	DNA-binding transcription factor activity
F3113_RS04605	COG0427	acetyl-CoA hydrolase
F3113_RS04610	COG1024	Enoyl-CoA hydratase
F3113_RS04615	COG1703	isobutyryl-CoA mutase activity
F3113_RS04620	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F3113_RS04620	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F3113_RS04635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3113_RS04640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F3113_RS04660	COG0006	proline dipeptidase activity
F3113_RS04665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3113_RS04670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3113_RS04690	COG1028	Short-chain dehydrogenase reductase Sdr
F3113_RS04695	COG2723	6-phospho-beta-galactosidase activity
F3113_RS04700	COG1737	Transcriptional regulator
F3113_RS04710	COG1272	protein, Hemolysin III
F3113_RS04720	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F3113_RS04745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F3113_RS04765	COG4942	peptidase
F3113_RS04875	COG0457	Tetratricopeptide repeat
F3113_RS04880	COG0726	polysaccharide deacetylase
F3113_RS04880	COG1649	PFAM Uncharacterised BCR, COG1649
F3113_RS04885	COG1215	transferase activity, transferring glycosyl groups
F3113_RS04895	COG3592	Divergent 4Fe-4S mono-cluster
F3113_RS04900	COG2388	GCN5-related N-acetyl-transferase
F3113_RS04905	COG0583	DNA-binding transcription factor activity
F3113_RS04910	COG0666	response to abiotic stimulus
F3113_RS04920	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F3113_RS04925	COG1304	FMN binding
F3113_RS04935	COG0549	Belongs to the carbamate kinase family
F3113_RS04940	COG0402	S-adenosylhomocysteine deaminase activity
F3113_RS04955	COG0814	amino acid
F3113_RS04970	COG0183	Belongs to the thiolase family
F3113_RS04980	COG1028	Short-chain dehydrogenase reductase Sdr
F3113_RS04985	COG2814	Major facilitator Superfamily
F3113_RS04990	COG5464	transposase or invertase
F3113_RS05000	COG1794	racemase activity, acting on amino acids and derivatives
F3113_RS05005	COG0583	DNA-binding transcription factor activity
F3113_RS05015	COG1609	Transcriptional regulator
F3113_RS05035	COG0667	Aldo Keto reductase
F3113_RS05045	COG0861	Integral membrane protein TerC family
F3113_RS05075	COG2165	general secretion pathway protein
F3113_RS05080	COG4795	General secretion pathway protein
F3113_RS05090	COG4967	type IV pilus modification protein PilV
F3113_RS05095	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F3113_RS05105	COG1074	ATP-dependent DNA helicase activity
F3113_RS05110	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3113_RS05115	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F3113_RS05115	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F3113_RS05120	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3113_RS05145	COG3121	Chaperone
F3113_RS05150	COG3188	usher protein
F3113_RS05175	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F3113_RS05180	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F3113_RS05185	COG2166	iron-sulfur cluster assembly
F3113_RS05190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F3113_RS05200	COG0583	DNA-binding transcription factor activity
F3113_RS05205	COG2363	Small membrane protein
F3113_RS05215	COG1349	DNA-binding transcription factor activity
F3113_RS05225	COG1070	Carbohydrate kinase
F3113_RS05235	COG1129	ABC transporter
F3113_RS05240	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3113_RS05250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F3113_RS05260	COG0235	Class ii aldolase
F3113_RS05265	COG1454	alcohol dehydrogenase
F3113_RS05275	COG1760	l-serine dehydratase
F3113_RS05280	COG0814	amino acid
F3113_RS05285	COG1611	Belongs to the LOG family
F3113_RS05300	COG3098	single-species biofilm formation
F3113_RS05305	COG0564	pseudouridine synthase activity
F3113_RS05310	COG0716	FMN binding
F3113_RS05315	COG2271	Major facilitator Superfamily
F3113_RS05320	COG4948	Mandelate Racemase Muconate Lactonizing
F3113_RS05325	COG4948	Mandelate Racemase Muconate Lactonizing
F3113_RS05330	COG1929	Belongs to the glycerate kinase type-1 family
F3113_RS05335	COG2205	protein histidine kinase activity
F3113_RS05335	COG3437	response regulator, receiver
F3113_RS05335	COG3850	Histidine kinase
F3113_RS05335	COG4999	Histidine kinase
F3113_RS05345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F3113_RS05350	COG3956	TIGRFAM MazG family protein
F3113_RS05365	COG1737	Transcriptional regulator
F3113_RS05370	COG1263	PTS System
F3113_RS05370	COG2190	(PTS) system
F3113_RS05370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3113_RS05375	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
F3113_RS05380	COG0602	queuosine metabolic process
F3113_RS05385	COG0720	synthase
F3113_RS05405	COG2234	aminopeptidase activity
F3113_RS05460	COG1388	LysM domain
F3113_RS05460	COG4942	peptidase
F3113_RS05475	COG0163	prenyltransferase activity
F3113_RS05480	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F3113_RS05505	COG0628	permease
F3113_RS05510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3113_RS05530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F3113_RS05535	COG1882	Formate acetyltransferase
F3113_RS05550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3113_RS05555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3113_RS05560	COG1121	(ABC) transporter
F3113_RS05580	COG0309	Hydrogenase expression formation protein (HypE)
F3113_RS05585	COG0409	Hydrogenase expression formation protein
F3113_RS05590	COG0298	carbon dioxide binding
F3113_RS05595	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F3113_RS05600	COG0375	protein maturation
F3113_RS05610	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3113_RS05615	COG0651	ATP synthesis coupled electron transport
F3113_RS05620	COG0650	Formate hydrogenlyase subunit 4
F3113_RS05625	COG3261	NADH dehydrogenase
F3113_RS05625	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
F3113_RS05630	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3113_RS05635	COG3260	NADH ubiquinone oxidoreductase 20
F3113_RS05645	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F3113_RS05655	COG2723	6-phospho-beta-galactosidase activity
F3113_RS05665	COG1609	Transcriptional regulator
F3113_RS05670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3113_RS05675	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
F3113_RS05695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F3113_RS05695	COG0517	IMP dehydrogenase activity
F3113_RS05700	COG1349	DNA-binding transcription factor activity
F3113_RS05705	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3113_RS05710	COG1028	Short-chain dehydrogenase reductase Sdr
F3113_RS05720	COG3732	PTS system glucitol sorbitol-specific
F3113_RS05725	COG3730	PTS system glucitol sorbitol-specific
F3113_RS05730	COG2951	lytic endotransglycosylase activity
F3113_RS05735	COG1546	Belongs to the CinA family
F3113_RS05755	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
F3113_RS05780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3113_RS05785	COG1238	metal cluster binding
F3113_RS05805	COG2814	Major facilitator Superfamily
F3113_RS05810	COG1566	PFAM secretion protein HlyD family protein
F3113_RS05815	COG1846	Transcriptional regulator
F3113_RS05825	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F3113_RS05830	COG2814	Major facilitator Superfamily
F3113_RS05840	COG4176	ABC-type proline glycine betaine transport system permease component
F3113_RS05870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3113_RS05900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3113_RS05905	COG0640	Transcriptional regulator
F3113_RS05910	COG0401	homolog of Blt101
F3113_RS05915	COG1652	LysM domain
F3113_RS05920	COG1802	Transcriptional regulator
F3113_RS05925	COG1113	amino acid transport
F3113_RS05930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3113_RS05935	COG1012	belongs to the aldehyde dehydrogenase family
F3113_RS05940	COG0579	oxidoreductase
F3113_RS05950	COG1285	pathogenesis
F3113_RS05955	COG2211	Major facilitator Superfamily
F3113_RS06010	COG3188	usher protein
F3113_RS06015	COG3121	Chaperone
F3113_RS06060	COG0438	transferase activity, transferring glycosyl groups
F3113_RS06065	COG0438	transferase activity, transferring glycosyl groups
F3113_RS06065	COG0297	glycogen (starch) synthase activity
F3113_RS06100	COG3829	transcription factor binding
F3113_RS06105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3113_RS06110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3113_RS06115	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F3113_RS06120	COG2271	Major facilitator Superfamily
F3113_RS06125	COG2197	response regulator
F3113_RS06130	COG0784	Response regulator, receiver
F3113_RS06130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3113_RS06130	COG2198	Histidine kinase
F3113_RS06130	COG2205	protein histidine kinase activity
F3113_RS06150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3113_RS06155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3113_RS06160	COG3065	identical protein binding
F3113_RS06175	COG3962	Belongs to the TPP enzyme family
F3113_RS06180	COG0673	inositol 2-dehydrogenase activity
F3113_RS06195	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3113_RS06205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3113_RS06215	COG3718	enzyme involved in inositol metabolism
F3113_RS06225	COG1470	cell adhesion involved in biofilm formation
F3113_RS06225	COG1388	LysM domain
F3113_RS06300	COG0582	viral genome integration into host DNA
F3113_RS06310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3113_RS06335	COG2867	negative regulation of translational initiation
F3113_RS06350	COG0497	DNA recombination
F3113_RS06365	COG4536	flavin adenine dinucleotide binding
F3113_RS06370	COG4137	Cytochrome C assembly protein
F3113_RS06375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F3113_RS06400	COG2885	chlorophyll binding
F3113_RS06405	COG2199	diguanylate cyclase activity
F3113_RS06420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F3113_RS06425	COG1605	Chorismate mutase
F3113_RS06425	COG0287	Prephenate dehydrogenase
F3113_RS06430	COG0077	Prephenate dehydratase
F3113_RS06430	COG1605	Chorismate mutase
F3113_RS06440	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F3113_RS06445	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3113_RS06460	COG0542	response to heat
F3113_RS06485	COG0477	Major facilitator Superfamily
F3113_RS06490	COG5544	Lipoprotein
F3113_RS06495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3113_RS06505	COG3148	PFAM DTW domain containing protein
F3113_RS06510	COG3118	belongs to the thioredoxin family
F3113_RS06515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3113_RS06540	COG0513	Belongs to the DEAD box helicase family
F3113_RS06550	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F3113_RS06560	COG1595	DNA-templated transcription, initiation
F3113_RS06565	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
F3113_RS06570	COG3026	antisigma factor binding
F3113_RS06575	COG3086	response to oxidative stress
F3113_RS06585	COG0681	Belongs to the peptidase S26 family
F3113_RS06605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F3113_RS06615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3113_RS06620	COG1737	Transcriptional regulator
F3113_RS06625	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F3113_RS06630	COG1263	PTS System
F3113_RS06630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3113_RS06635	COG0560	Phosphoserine phosphatase
F3113_RS06655	COG2205	protein histidine kinase activity
F3113_RS06660	COG3170	Tfp pilus assembly protein FimV
F3113_RS06665	COG2204	response regulator
F3113_RS06670	COG0347	Belongs to the P(II) protein family
F3113_RS06675	COG1017	nitric oxide dioxygenase activity
F3113_RS06675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3113_RS06705	COG4638	Rieske (2fe-2S)
F3113_RS06710	COG0583	DNA-binding transcription factor activity
F3113_RS06715	COG1940	carbohydrate kinase activity
F3113_RS06720	COG0457	Tetratricopeptide repeat
F3113_RS06725	COG0477	Major facilitator Superfamily
F3113_RS06725	COG2814	Major facilitator Superfamily
F3113_RS06735	COG2814	Major facilitator Superfamily
F3113_RS06740	COG3711	transcriptional antiterminator
F3113_RS06745	COG0517	IMP dehydrogenase activity
F3113_RS06745	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F3113_RS06750	COG1069	ribulokinase activity
F3113_RS06760	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3113_RS06765	COG1129	ABC transporter
F3113_RS06775	COG3683	transport system, periplasmic component
F3113_RS06780	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F3113_RS06800	COG1104	cysteine desulfurase activity
F3113_RS06805	COG0822	iron-sulfur transferase activity
F3113_RS06825	COG0633	Ferredoxin
F3113_RS06830	COG2975	iron-sulfur cluster assembly
F3113_RS06845	COG2897	thiosulfate sulfurtransferase activity
F3113_RS06850	COG2373	Large extracellular alpha-helical protein
F3113_RS06855	COG4953	penicillin-binding protein 1C
F3113_RS06870	COG1426	Protein conserved in bacteria
F3113_RS06885	COG2976	Protein conserved in bacteria
F3113_RS06910	COG1645	bacterial-type flagellum-dependent swarming motility
F3113_RS06935	COG0516	GMP reductase activity
F3113_RS06935	COG0517	IMP dehydrogenase activity
F3113_RS06960	COG0668	transmembrane transport
F3113_RS06970	COG2200	EAL domain
F3113_RS06975	COG0248	Ppx GppA phosphatase
F3113_RS06985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F3113_RS06995	COG2723	6-phospho-beta-galactosidase activity
F3113_RS07005	COG2233	PERMEase
F3113_RS07015	COG1393	Belongs to the ArsC family
F3113_RS07020	COG4783	chaperone-mediated protein folding
F3113_RS07025	COG0628	permease
F3113_RS07030	COG3366	ferrous iron transmembrane transporter activity
F3113_RS07035	COG0700	Nucleoside recognition
F3113_RS07040	COG3385	transposase activity
F3113_RS07045	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F3113_RS07050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F3113_RS07055	COG2716	regulation of RNA biosynthetic process
F3113_RS07065	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
F3113_RS07075	COG2321	neutral zinc metallopeptidase
F3113_RS07085	COG0400	carboxylic ester hydrolase activity
F3113_RS07100	COG1393	Belongs to the ArsC family
F3113_RS07110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3113_RS07115	COG3850	Histidine kinase
F3113_RS07120	COG0493	'glutamate synthase
F3113_RS07120	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3113_RS07130	COG5342	invasion associated locus B
F3113_RS07135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F3113_RS07155	COG4766	ethanolamine catabolic process
F3113_RS07160	COG4812	Cobalamin adenosyltransferase
F3113_RS07220	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
F3113_RS07225	COG2207	Transcriptional regulator
F3113_RS07235	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3113_RS07255	COG2837	iron assimilation
F3113_RS07270	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F3113_RS07275	COG4208	sulfate ABC transporter
F3113_RS07280	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F3113_RS07345	COG3530	Putative quorum-sensing-regulated virulence factor
F3113_RS07350	COG0385	Bile acid
F3113_RS07355	COG0583	DNA-binding transcription factor activity
F3113_RS07365	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
F3113_RS07370	COG2211	Major facilitator Superfamily
F3113_RS07380	COG0583	DNA-binding transcription factor activity
F3113_RS07405	COG3415	Transposase
F3113_RS07410	COG3415	Transposase
F3113_RS07425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3113_RS07440	COG0667	Aldo Keto reductase
F3113_RS07445	COG3961	Belongs to the TPP enzyme family
F3113_RS07460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS07465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS07470	COG0006	proline dipeptidase activity
F3113_RS07475	COG1363	Peptidase, m42
F3113_RS07495	COG2207	Transcriptional regulator
F3113_RS07500	COG3279	Response regulator of the LytR AlgR family
F3113_RS07505	COG3275	phosphorelay sensor kinase activity
F3113_RS07510	COG0436	Aminotransferase
F3113_RS07525	COG1560	Kdo2-lipid A biosynthetic process
F3113_RS07555	COG3122	Protein conserved in bacteria
F3113_RS07560	COG0840	transmembrane signaling receptor activity
F3113_RS07575	COG2116	formate transmembrane transporter activity
F3113_RS07585	COG2067	long-chain fatty acid transport protein
F3113_RS07590	COG3691	Protein conserved in bacteria
F3113_RS07605	COG2062	phosphohistidine phosphatase, SixA
F3113_RS07630	COG0730	response to heat
F3113_RS07635	COG3101	peptidyl-lysine hydroxylation
F3113_RS07650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3113_RS07670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F3113_RS07680	COG0586	Pfam SNARE associated Golgi protein
F3113_RS07690	COG0285	dihydrofolate synthase activity
F3113_RS07695	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
F3113_RS07700	COG1286	toxin biosynthetic process
F3113_RS07705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F3113_RS07710	COG0163	prenyltransferase activity
F3113_RS07720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3113_RS07725	COG4215	(ABC) transporter
F3113_RS07735	COG4598	ABC transporter
F3113_RS07740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3113_RS07745	COG1090	epimerase
F3113_RS07750	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F3113_RS07755	COG0625	glutathione transferase activity
F3113_RS07760	COG0625	glutathione transferase activity
F3113_RS07765	COG0622	Phosphoesterase
F3113_RS07775	COG1288	antiporter activity
F3113_RS07800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3113_RS07805	COG0490	domain, Protein
F3113_RS07805	COG0471	metal ion transport
F3113_RS07815	COG0436	Aminotransferase
F3113_RS07820	COG0583	DNA-binding transcription factor activity
F3113_RS07840	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F3113_RS07865	COG0839	Belongs to the complex I subunit 6 family
F3113_RS07875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3113_RS07880	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3113_RS07890	COG0835	chemotaxis
F3113_RS07890	COG0784	Response regulator, receiver
F3113_RS07900	COG2153	protein acetylation
F3113_RS07905	COG4575	ribosome binding
F3113_RS07910	COG1169	isochorismate synthase
F3113_RS08000	COG0247	lactate metabolic process
F3113_RS08010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F3113_RS08020	COG0584	glycerophosphoryl diester phosphodiesterase
F3113_RS08025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3113_RS08060	COG2198	Histidine kinase
F3113_RS08060	COG0642	Histidine kinase
F3113_RS08065	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F3113_RS08070	COG1477	protein flavinylation
F3113_RS08075	COG2169	Transcriptional regulator
F3113_RS08075	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3113_RS08080	COG3145	DNA-N1-methyladenine dioxygenase activity
F3113_RS08085	COG4615	Cyclic peptide transporter
F3113_RS08090	COG2239	Acts as a magnesium transporter
F3113_RS08095	COG0659	secondary active sulfate transmembrane transporter activity
F3113_RS08110	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3113_RS08110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3113_RS08115	COG3062	negative regulation of establishment of protein localization
F3113_RS08125	COG0437	4 iron, 4 sulfur cluster binding
F3113_RS08130	COG0348	domain, Protein
F3113_RS08135	COG3043	anaerobic respiration
F3113_RS08140	COG3005	denitrification pathway
F3113_RS08145	COG4133	protoheme IX ABC transporter activity
F3113_RS08155	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3113_RS08160	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3113_RS08170	COG1138	Cytochrome C-type biogenesis protein
F3113_RS08175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3113_RS08180	COG3088	subunit of a heme lyase
F3113_RS08180	COG4235	cytochrome complex assembly
F3113_RS08185	COG2197	response regulator
F3113_RS08240	COG1061	Type III restriction enzyme res subunit
F3113_RS08245	COG1187	pseudouridine synthase activity
F3113_RS08250	COG2814	Major facilitator Superfamily
F3113_RS08260	COG4172	Belongs to the ABC transporter superfamily
F3113_RS08265	COG4239	(ABC) transporter, permease
F3113_RS08270	COG4174	ABC transporter (Permease)
F3113_RS08275	COG4166	transmembrane transport
F3113_RS08280	COG2200	EAL domain
F3113_RS08285	COG0791	NLP P60 protein
F3113_RS08290	COG0671	phosphoesterase, PA-phosphatase related
F3113_RS08295	COG0523	cobalamin synthesis protein
F3113_RS08300	COG0246	Mannitol dehydrogenase
F3113_RS08305	COG1312	Catalyzes the dehydration of D-mannonate
F3113_RS08310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3113_RS08315	COG3005	denitrification pathway
F3113_RS08325	COG3381	protein complex oligomerization
F3113_RS08355	COG4372	Transposase
F3113_RS08415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F3113_RS08435	COG1105	Belongs to the carbohydrate kinase PfkB family
F3113_RS08440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS08440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS08440	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F3113_RS08445	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F3113_RS08455	COG0583	DNA-binding transcription factor activity
F3113_RS08460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3113_RS08465	COG2313	pseudouridylate synthase activity
F3113_RS08470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3113_RS08475	COG1522	sequence-specific DNA binding
F3113_RS08475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3113_RS08485	COG2855	membrane
F3113_RS08490	COG0583	DNA-binding transcription factor activity
F3113_RS08495	COG0833	amino acid
F3113_RS08500	COG4771	TonB-dependent receptor
F3113_RS08505	COG2271	Major facilitator Superfamily
F3113_RS08510	COG0560	Phosphoserine phosphatase
F3113_RS08515	COG1760	l-serine dehydratase
F3113_RS08535	COG2311	Membrane
F3113_RS08550	COG1129	ABC transporter
F3113_RS08565	COG0493	'glutamate synthase
F3113_RS08575	COG2949	membrane
F3113_RS08585	COG1346	cytolysis
F3113_RS08600	COG2271	Major facilitator Superfamily
F3113_RS08615	COG0625	glutathione transferase activity
F3113_RS08620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3113_RS08625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3113_RS08645	COG0586	Pfam SNARE associated Golgi protein
F3113_RS08655	COG1686	Belongs to the peptidase S11 family
F3113_RS08660	COG0277	FAD linked oxidase domain protein
F3113_RS08665	COG1472	Belongs to the glycosyl hydrolase 3 family
F3113_RS08670	COG1732	Glycine betaine
F3113_RS08675	COG1174	glycine betaine transport
F3113_RS08680	COG1125	glycine betaine transport
F3113_RS08685	COG1174	glycine betaine transport
F3113_RS08695	COG0789	Transcriptional regulator
F3113_RS08700	COG3275	phosphorelay sensor kinase activity
F3113_RS08710	COG4807	Protein conserved in bacteria
F3113_RS08715	COG4808	Protein conserved in bacteria
F3113_RS08725	COG0489	protein tyrosine kinase activity
F3113_RS08740	COG3121	Chaperone
F3113_RS08745	COG3188	usher protein
F3113_RS08755	COG5455	response to cobalt ion
F3113_RS08780	COG0582	viral genome integration into host DNA
F3113_RS08860	COG0351	phosphomethylpyrimidine kinase
F3113_RS08865	COG2188	Transcriptional regulator
F3113_RS08870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3113_RS08875	COG1397	ADP-ribosylglycohydrolase
F3113_RS08880	COG2211	Major facilitator Superfamily
F3113_RS08885	COG1830	Aldolase
F3113_RS08895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3113_RS08900	COG4160	amino acid transport
F3113_RS08905	COG4215	(ABC) transporter
F3113_RS08910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3113_RS08915	COG1126	abc transporter atp-binding protein
F3113_RS08930	COG3023	N-Acetylmuramoyl-L-alanine amidase
F3113_RS08935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3113_RS08940	COG0702	epimerase
F3113_RS08945	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
F3113_RS08950	COG0028	Belongs to the TPP enzyme family
F3113_RS08960	COG4529	Protein conserved in bacteria
F3113_RS08965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3113_RS08975	COG2431	L-lysine efflux transmembrane transporter activity
F3113_RS08985	COG3593	DNA synthesis involved in DNA repair
F3113_RS08990	COG2990	Protein conserved in bacteria
F3113_RS08995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3113_RS09005	COG1278	Cold shock
F3113_RS09015	COG0542	response to heat
F3113_RS09020	COG0826	peptidase U32
F3113_RS09030	COG0745	RESPONSE REGULATOR receiver
F3113_RS09035	COG2205	protein histidine kinase activity
F3113_RS09065	COG0443	Heat shock 70 kDa protein
F3113_RS09070	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F3113_RS09075	COG3447	MASE1 domain protein
F3113_RS09075	COG5002	protein histidine kinase activity
F3113_RS09075	COG5001	Diguanylate cyclase
F3113_RS09090	COG2982	Protein involved in outer membrane biogenesis
F3113_RS09095	COG1253	flavin adenine dinucleotide binding
F3113_RS09115	COG0463	Glycosyl transferase, family 2
F3113_RS09120	COG1045	serine acetyltransferase
F3113_RS09125	COG0438	transferase activity, transferring glycosyl groups
F3113_RS09135	COG1216	Glycosyl transferase, family 2
F3113_RS09140	COG0110	maltose O-acetyltransferase activity
F3113_RS09145	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
F3113_RS09150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3113_RS09155	COG1051	belongs to the nudix hydrolase family
F3113_RS09160	COG0297	glycogen (starch) synthase activity
F3113_RS09170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3113_RS09175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F3113_RS09180	COG2244	polysaccharide biosynthetic process
F3113_RS09185	COG2327	Polysaccharide pyruvyl transferase
F3113_RS09255	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F3113_RS09270	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
F3113_RS09275	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F3113_RS09275	COG0140	phosphoribosyl-ATP diphosphatase activity
F3113_RS09290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F3113_RS09320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3113_RS09325	COG0583	DNA-binding transcription factor activity
F3113_RS09335	COG0531	amino acid
F3113_RS09340	COG2925	Exonuclease
F3113_RS09380	COG1289	transmembrane transporter activity
F3113_RS09415	COG4656	Part of a membrane complex involved in electron transport
F3113_RS09425	COG1012	belongs to the aldehyde dehydrogenase family
F3113_RS09435	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
F3113_RS09605	COG1376	ErfK ybiS ycfS ynhG family protein
F3113_RS09610	COG3842	ATPase activity
F3113_RS09615	COG1178	ABC-type Fe3 transport system permease component
F3113_RS09620	COG1840	ABC-type Fe3 transport system, periplasmic component
F3113_RS09640	COG2076	Multidrug Resistance protein
F3113_RS09645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F3113_RS09650	COG1418	mRNA catabolic process
F3113_RS09655	COG0270	DNA (cytosine-5-)-methyltransferase activity
F3113_RS09660	COG3727	T/G mismatch-specific endonuclease activity
F3113_RS09665	COG0697	spore germination
F3113_RS09670	COG2354	Protein conserved in bacteria
F3113_RS09675	COG5475	Uncharacterized small protein (DUF2158)
F3113_RS09735	COG2882	bacterial-type flagellum organization
F3113_RS09740	COG1157	protein secretion by the type III secretion system
F3113_RS09765	COG0425	Belongs to the sulfur carrier protein TusA family
F3113_RS09780	COG0366	Alpha amylase catalytic
F3113_RS09815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3113_RS09825	COG0765	amino acid transport
F3113_RS09830	COG1126	abc transporter atp-binding protein
F3113_RS09835	COG2197	response regulator
F3113_RS09845	COG2197	response regulator
F3113_RS09875	COG4974	Belongs to the 'phage' integrase family
F3113_RS09935	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F3113_RS09960	COG4695	Portal protein
F3113_RS10105	COG1305	Transglutaminase-like
F3113_RS10115	COG2608	mercury ion transmembrane transporter activity
F3113_RS10120	COG3318	Belongs to the UPF0149 family
F3113_RS10120	COG3012	SEC-C Motif Domain Protein
F3113_RS10125	COG0814	amino acid
F3113_RS10135	COG1528	Iron-storage protein
F3113_RS10150	COG0477	Major facilitator Superfamily
F3113_RS10160	COG1528	Iron-storage protein
F3113_RS10170	COG1879	ABC-type sugar transport system periplasmic component
F3113_RS10175	COG1129	ABC transporter
F3113_RS10180	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3113_RS10195	COG0589	response to stress
F3113_RS10225	COG0835	chemotaxis
F3113_RS10235	COG1301	dicarboxylic acid transport
F3113_RS10245	COG0840	transmembrane signaling receptor activity
F3113_RS10260	COG0745	RESPONSE REGULATOR receiver
F3113_RS10285	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F3113_RS10300	COG3102	Protein conserved in bacteria
F3113_RS10320	COG3788	relative of glutathione S-transferase, MAPEG superfamily
F3113_RS10325	COG1801	Protein of unknown function DUF72
F3113_RS10330	COG0582	viral genome integration into host DNA
F3113_RS10415	COG4626	Terminase
F3113_RS10415	COG1802	Transcriptional regulator
F3113_RS10420	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F3113_RS10430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F3113_RS10445	COG1403	HNH endonuclease
F3113_RS10470	COG3179	chitinase
F3113_RS10490	COG3646	Phage regulatory protein
F3113_RS10510	COG3436	PFAM IS66 Orf2 family protein
F3113_RS10515	COG4372	Transposase
F3113_RS10540	COG0740	serine-type endopeptidase activity
F3113_RS10640	COG2135	peptidase activity
F3113_RS10645	COG1335	isochorismatase
F3113_RS10655	COG0494	nUDIX hydrolase
F3113_RS10680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3113_RS10690	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
F3113_RS10695	COG0739	heme binding
F3113_RS10700	COG1560	Kdo2-lipid A biosynthetic process
F3113_RS10710	COG1737	Transcriptional regulator
F3113_RS10715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F3113_RS10720	COG0129	dihydroxy-acid dehydratase activity
F3113_RS10725	COG0800	Aldolase
F3113_RS10735	COG3141	response to X-ray
F3113_RS10745	COG2979	Protein of unknown function (DUF533)
F3113_RS10750	COG1770	oligopeptidase
F3113_RS10755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3113_RS10760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3113_RS10785	COG3706	GGDEF domain
F3113_RS10795	COG2372	response to copper ion
F3113_RS10800	COG1276	copper resistance
F3113_RS10810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F3113_RS10830	COG3008	intermembrane lipid transfer
F3113_RS10835	COG2995	paraquat-inducible protein a
F3113_RS10840	COG1956	GAF domain-containing protein
F3113_RS10960	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3113_RS10990	COG2197	response regulator
F3113_RS11005	COG2814	Major facilitator Superfamily
F3113_RS11010	COG1414	Transcriptional regulator
F3113_RS11040	COG0768	penicillin binding
F3113_RS11045	COG2226	methyltransferase
F3113_RS11060	COG3716	PTS system mannose fructose sorbose family IID component
F3113_RS11065	COG3715	PTS system
F3113_RS11070	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3113_RS11070	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3113_RS11075	COG1253	flavin adenine dinucleotide binding
F3113_RS11080	COG2200	EAL domain
F3113_RS11085	COG1760	l-serine dehydratase
F3113_RS11105	COG0251	oxidation-reduction process
F3113_RS11110	COG1199	ATP-dependent helicase activity
F3113_RS11115	COG1214	PFAM Peptidase M22, glycoprotease
F3113_RS11120	COG3065	identical protein binding
F3113_RS11125	COG0318	PFAM AMP-dependent synthetase and ligase
F3113_RS11130	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F3113_RS11135	COG0473	3-isopropylmalate dehydrogenase activity
F3113_RS11140	COG0583	DNA-binding transcription factor activity
F3113_RS11150	COG2894	cell division
F3113_RS11165	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3113_RS11195	COG2719	SpoVR family
F3113_RS11205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F3113_RS11215	COG1619	proteins homologs of microcin C7 resistance protein MccF
F3113_RS11240	COG0157	Belongs to the NadC ModD family
F3113_RS11250	COG1120	ATPase activity
F3113_RS11255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3113_RS11260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3113_RS11275	COG1461	Dihydroxyacetone kinase
F3113_RS11280	COG2376	Dihydroxyacetone kinase
F3113_RS11285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F3113_RS11315	COG0789	Transcriptional regulator
F3113_RS11320	COG2200	EAL domain
F3113_RS11365	COG0012	GTP binding
F3113_RS11380	COG0527	aspartate kinase activity
F3113_RS11385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3113_RS11390	COG0076	glutamate decarboxylase activity
F3113_RS11395	COG0659	secondary active sulfate transmembrane transporter activity
F3113_RS11425	COG2890	protein-(glutamine-N5) methyltransferase activity
F3113_RS11430	COG3094	Invasion gene expression up-regulator, SirB
F3113_RS11445	COG0387	Pfam Sodium calcium exchanger
F3113_RS11450	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
F3113_RS11460	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F3113_RS11465	COG4932	domain protein
F3113_RS11470	COG2197	response regulator
F3113_RS11475	COG3850	Histidine kinase
F3113_RS11480	COG2223	nitrite transmembrane transporter activity
F3113_RS11485	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F3113_RS11490	COG1140	nitrate reductase beta subunit
F3113_RS11495	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F3113_RS11500	COG2181	nitrate reductase activity
F3113_RS11525	COG0788	formyltetrahydrofolate deformylase activity
F3113_RS11535	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3113_RS11540	COG0745	RESPONSE REGULATOR receiver
F3113_RS11545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3113_RS11555	COG1435	thymidine kinase activity
F3113_RS11560	COG1012	belongs to the aldehyde dehydrogenase family
F3113_RS11560	COG1454	alcohol dehydrogenase
F3113_RS11565	COG2095	MarC family integral membrane protein
F3113_RS11585	COG0444	Belongs to the ABC transporter superfamily
F3113_RS11595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3113_RS11615	COG2350	Protein conserved in bacteria
F3113_RS11640	COG3047	cAMP biosynthetic process
F3113_RS11645	COG0217	transcriptional regulatory protein
F3113_RS11660	COG3706	GGDEF domain
F3113_RS11700	COG0009	L-threonylcarbamoyladenylate synthase
F3113_RS11705	COG1187	pseudouridine synthase activity
F3113_RS11715	COG1028	Short-chain dehydrogenase reductase Sdr
F3113_RS11720	COG0616	signal peptide processing
F3113_RS11735	COG0583	DNA-binding transcription factor activity
F3113_RS11750	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F3113_RS11760	COG0671	phosphoesterase, PA-phosphatase related
F3113_RS11765	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
F3113_RS11770	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
F3113_RS11780	COG0023	Translation Initiation Factor
F3113_RS11790	COG1349	DNA-binding transcription factor activity
F3113_RS11800	COG5001	Diguanylate cyclase
F3113_RS11810	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3113_RS11810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3113_RS11815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F3113_RS11835	COG4171	peptide transport system, permease
F3113_RS11860	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F3113_RS11865	COG1842	Phage shock protein A
F3113_RS11875	COG1983	PspC domain protein
F3113_RS11885	COG0366	Alpha amylase catalytic
F3113_RS11890	COG1653	transport
F3113_RS11895	COG1175	transmembrane transport
F3113_RS11900	COG0395	ABC-type sugar transport system, permease component
F3113_RS11905	COG1063	alcohol dehydrogenase
F3113_RS11910	COG1082	Xylose isomerase domain protein TIM barrel
F3113_RS11915	COG0673	inositol 2-dehydrogenase activity
F3113_RS11920	COG1554	hydrolase, family 65, central catalytic
F3113_RS11925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3113_RS11930	COG3842	ATPase activity
F3113_RS11940	COG1609	Transcriptional regulator
F3113_RS11945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3113_RS11950	COG3106	COG3106 Predicted ATPase
F3113_RS11965	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F3113_RS11970	COG4948	Mandelate Racemase Muconate Lactonizing
F3113_RS11975	COG2866	Carboxypeptidase
F3113_RS11980	COG4166	transmembrane transport
F3113_RS12000	COG1349	DNA-binding transcription factor activity
F3113_RS12005	COG0346	lactoylglutathione lyase activity
F3113_RS12015	COG1064	alcohol dehydrogenase
F3113_RS12020	COG0668	transmembrane transport
F3113_RS12025	COG3182	Iron-regulated membrane protein
F3113_RS12045	COG2840	Smr protein MutS2
F3113_RS12050	COG3706	GGDEF domain
F3113_RS12060	COG0840	transmembrane signaling receptor activity
F3113_RS12070	COG0513	Belongs to the DEAD box helicase family
F3113_RS12080	COG0589	response to stress
F3113_RS12090	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F3113_RS12095	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
F3113_RS12095	COG1013	pyruvate-flavodoxin oxidoreductase activity
F3113_RS12095	COG0674	pyruvate-flavodoxin oxidoreductase activity
F3113_RS12095	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3113_RS12100	COG3042	response to heat
F3113_RS12105	COG3187	Heat shock protein
F3113_RS12110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3113_RS12115	COG2911	Protein conserved in bacteria
F3113_RS12125	COG3784	Protein of unknown function (DUF1318)
F3113_RS12140	COG1643	Atp-dependent helicase
F3113_RS12145	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F3113_RS12150	COG1012	belongs to the aldehyde dehydrogenase family
F3113_RS12155	COG0657	acetylesterase activity
F3113_RS12155	COG2755	lipolytic protein G-D-S-L family
F3113_RS12160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F3113_RS12165	COG3038	cytochrome b561
F3113_RS12175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F3113_RS12180	COG2864	formate dehydrogenase
F3113_RS12185	COG0437	4 iron, 4 sulfur cluster binding
F3113_RS12190	COG0243	molybdopterin cofactor binding
F3113_RS12190	COG3383	formate dehydrogenase (NAD+) activity
F3113_RS12200	COG3059	membrane
F3113_RS12220	COG0840	transmembrane signaling receptor activity
F3113_RS12245	COG3121	Chaperone
F3113_RS12255	COG0583	DNA-binding transcription factor activity
F3113_RS12265	COG5383	Protein conserved in bacteria
F3113_RS12275	COG2841	Protein conserved in bacteria
F3113_RS12285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3113_RS12290	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F3113_RS12295	COG1275	C4-dicarboxylate transporter malic acid transport protein
F3113_RS12300	COG0500	methyltransferase
F3113_RS12320	COG3135	benzoate transporter
F3113_RS12325	COG1396	sequence-specific DNA binding
F3113_RS12330	COG0826	peptidase U32
F3113_RS12345	COG1294	oxidase, subunit
F3113_RS12350	COG1271	oxidase subunit
F3113_RS12360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3113_RS12365	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3113_RS12370	COG3842	ATPase activity
F3113_RS12375	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3113_RS12380	COG1177	transmembrane transport
F3113_RS12420	COG0747	negative chemotaxis
F3113_RS12430	COG3238	Protein conserved in bacteria
F3113_RS12435	COG1247	-acetyltransferase
F3113_RS12445	COG2130	NADP-dependent
F3113_RS12465	COG0840	transmembrane signaling receptor activity
F3113_RS12470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3113_RS12475	COG1473	amidohydrolase
F3113_RS12480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3113_RS12485	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
F3113_RS12500	COG1126	abc transporter atp-binding protein
F3113_RS12505	COG0604	alcohol dehydrogenase
F3113_RS12505	COG1028	Short-chain dehydrogenase reductase Sdr
F3113_RS12505	COG3321	synthase
F3113_RS12510	COG0583	DNA-binding transcription factor activity
F3113_RS12515	COG0625	glutathione transferase activity
F3113_RS12530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3113_RS12535	COG2162	N-hydroxyarylamine O-acetyltransferase activity
F3113_RS12555	COG0384	phenazine biosynthesis protein PhzF
F3113_RS12560	COG2181	nitrate reductase activity
F3113_RS12565	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F3113_RS12570	COG1140	nitrate reductase beta subunit
F3113_RS12575	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F3113_RS12580	COG2223	nitrite transmembrane transporter activity
F3113_RS12605	COG3039	Transposase
F3113_RS12610	COG0697	spore germination
F3113_RS12620	COG0437	4 iron, 4 sulfur cluster binding
F3113_RS12625	COG2864	formate dehydrogenase
F3113_RS12630	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F3113_RS12635	COG0488	(ABC) transporter
F3113_RS12650	COG1764	response to oxidative stress
F3113_RS12655	COG1028	Short-chain dehydrogenase reductase Sdr
F3113_RS12660	COG2610	gluconate transmembrane transporter activity
F3113_RS12665	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3113_RS12675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F3113_RS12680	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F3113_RS12690	COG4608	Belongs to the ABC transporter superfamily
F3113_RS12695	COG0444	Belongs to the ABC transporter superfamily
F3113_RS12700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3113_RS12705	COG0601	transmembrane transport
F3113_RS12710	COG0747	negative chemotaxis
F3113_RS12715	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
F3113_RS12730	COG0840	transmembrane signaling receptor activity
F3113_RS12750	COG1649	PFAM Uncharacterised BCR, COG1649
F3113_RS12755	COG4628	conserved protein (DUF2132)
F3113_RS12780	COG3121	Chaperone
F3113_RS12795	COG3121	Chaperone
F3113_RS12825	COG3781	membrane
F3113_RS12855	COG1012	belongs to the aldehyde dehydrogenase family
F3113_RS12860	COG0583	DNA-binding transcription factor activity
F3113_RS12875	COG1846	Transcriptional regulator
F3113_RS12890	COG0697	spore germination
F3113_RS12895	COG2814	Major facilitator Superfamily
F3113_RS12900	COG0410	ABC transporter
F3113_RS12905	COG1129	ABC transporter
F3113_RS12930	COG3706	GGDEF domain
F3113_RS12945	COG4221	oxidoreductase activity
F3113_RS12950	COG1802	Transcriptional regulator
F3113_RS12960	COG0246	Mannitol dehydrogenase
F3113_RS12970	COG4948	Mandelate Racemase Muconate Lactonizing
F3113_RS12985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3113_RS13000	COG0243	molybdopterin cofactor binding
F3113_RS13005	COG0437	4 iron, 4 sulfur cluster binding
F3113_RS13010	COG3302	dmso reductase anchor subunit
F3113_RS13015	COG3381	protein complex oligomerization
F3113_RS13025	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F3113_RS13030	COG1940	carbohydrate kinase activity
F3113_RS13035	COG0583	DNA-binding transcription factor activity
F3113_RS13040	COG2814	Major facilitator Superfamily
F3113_RS13050	COG2205	protein histidine kinase activity
F3113_RS13055	COG0745	RESPONSE REGULATOR receiver
F3113_RS13070	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
F3113_RS13080	COG3591	Belongs to the peptidase S1B family
F3113_RS13095	COG0628	permease
F3113_RS13100	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F3113_RS13105	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F3113_RS13115	COG0531	amino acid
F3113_RS13125	COG3136	membrane protein required for alginate biosynthesis
F3113_RS13130	COG0745	RESPONSE REGULATOR receiver
F3113_RS13135	COG1823	symporter activity
F3113_RS13140	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
F3113_RS13150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3113_RS13160	COG2205	protein histidine kinase activity
F3113_RS13175	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F3113_RS13175	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F3113_RS13185	COG5339	Protein conserved in bacteria
F3113_RS13190	COG1609	Transcriptional regulator
F3113_RS13195	COG1263	PTS System
F3113_RS13195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3113_RS13200	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F3113_RS13210	COG0673	inositol 2-dehydrogenase activity
F3113_RS13260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F3113_RS13270	COG0625	glutathione transferase activity
F3113_RS13275	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
F3113_RS13290	COG3895	Periplasmic Protein
F3113_RS13315	COG1566	PFAM secretion protein HlyD family protein
F3113_RS13325	COG2032	superoxide dismutase activity
F3113_RS13330	COG4989	oxidoreductase activity
F3113_RS13335	COG3313	Fe-S protein
F3113_RS13340	COG1309	transcriptional regulator
F3113_RS13345	COG1902	pentaerythritol trinitrate reductase activity
F3113_RS13350	COG0346	lactoylglutathione lyase activity
F3113_RS13360	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F3113_RS13365	COG0791	NLP P60 protein
F3113_RS13370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F3113_RS13375	COG2814	Major facilitator Superfamily
F3113_RS13390	COG0583	DNA-binding transcription factor activity
F3113_RS13395	COG2814	Major facilitator Superfamily
F3113_RS13400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3113_RS13405	COG0307	riboflavin synthase, alpha
F3113_RS13430	COG0251	oxidation-reduction process
F3113_RS13450	COG3300	MHYT domain
F3113_RS13450	COG5001	Diguanylate cyclase
F3113_RS13455	COG0386	Belongs to the glutathione peroxidase family
F3113_RS13460	COG0628	permease
F3113_RS13475	COG1028	Short-chain dehydrogenase reductase Sdr
F3113_RS13515	COG3121	Chaperone
F3113_RS13520	COG3188	usher protein
F3113_RS13535	COG4977	sequence-specific DNA binding
F3113_RS13565	COG1120	ATPase activity
F3113_RS13570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3113_RS13575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3113_RS13580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3113_RS13595	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
F3113_RS13605	COG1012	belongs to the aldehyde dehydrogenase family
F3113_RS13620	COG1113	amino acid transport
F3113_RS13630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3113_RS13645	COG0765	amino acid transport
F3113_RS13655	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
F3113_RS13660	COG0437	4 iron, 4 sulfur cluster binding
F3113_RS13670	COG2414	aldehyde ferredoxin oxidoreductase
F3113_RS13675	COG0437	4 iron, 4 sulfur cluster binding
F3113_RS13730	COG1464	Belongs to the NlpA lipoprotein family
F3113_RS13735	COG2011	ABC-type metal ion transport system permease component
F3113_RS13755	COG2267	carboxylic ester hydrolase activity
F3113_RS13760	COG0531	amino acid
F3113_RS13775	COG1376	ErfK ybiS ycfS ynhG family protein
F3113_RS13790	COG0719	Fe-S assembly protein
F3113_RS13795	COG0396	ATPase activity
F3113_RS13800	COG0719	Fe-S assembly protein
F3113_RS13805	COG0316	Belongs to the HesB IscA family
F3113_RS13810	COG0583	DNA-binding transcription factor activity
F3113_RS13825	COG2050	protein possibly involved in aromatic compounds catabolism
F3113_RS13830	COG0247	lactate metabolic process
F3113_RS13830	COG0277	FAD linked oxidase domain protein
F3113_RS13835	COG0628	permease
F3113_RS13850	COG0738	Major facilitator superfamily
F3113_RS13855	COG2271	Major facilitator Superfamily
F3113_RS13870	COG4670	ketone body catabolic process
F3113_RS13875	COG1960	acyl-CoA dehydrogenase activity
F3113_RS13880	COG2207	Transcriptional regulator
F3113_RS13880	COG1917	Cupin 2, conserved barrel domain protein
F3113_RS13885	COG2086	electron transfer activity
F3113_RS13890	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
F3113_RS13895	COG0644	oxidoreductase
F3113_RS13900	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
F3113_RS13905	COG0318	PFAM AMP-dependent synthetase and ligase
F3113_RS13910	COG0574	Belongs to the PEP-utilizing enzyme family
F3113_RS13910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F3113_RS13920	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F3113_RS13925	COG4256	Hemin uptake protein
F3113_RS13930	COG4771	TonB-dependent receptor
F3113_RS13935	COG3720	iron ion transport
F3113_RS13940	COG4558	Periplasmic binding protein
F3113_RS13945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3113_RS13965	COG0791	NLP P60 protein
F3113_RS13975	COG0386	Belongs to the glutathione peroxidase family
F3113_RS14010	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F3113_RS14030	COG3137	Salt-induced outer membrane protein
F3113_RS14035	COG1105	Belongs to the carbohydrate kinase PfkB family
F3113_RS14040	COG3001	Fructosamine kinase
F3113_RS14050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3113_RS14055	COG1028	Short-chain dehydrogenase reductase Sdr
F3113_RS14060	COG1988	membrane-bound metal-dependent
F3113_RS14065	COG1823	symporter activity
F3113_RS14075	COG0753	catalase activity
F3113_RS14085	COG1486	melibiose metabolic process
F3113_RS14090	COG1917	Cupin 2, conserved barrel domain protein
F3113_RS14090	COG2169	Transcriptional regulator
F3113_RS14095	COG1447	Phosphotransferase system cellobiose-specific component IIA
F3113_RS14100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3113_RS14105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3113_RS14110	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3113_RS14120	COG0322	excinuclease ABC activity
F3113_RS14130	COG3678	ATP-independent chaperone mediated protein folding
F3113_RS14160	COG0708	Exodeoxyribonuclease III
F3113_RS14165	COG0398	Pfam SNARE associated Golgi protein
F3113_RS14170	COG0398	Pfam SNARE associated Golgi protein
F3113_RS14175	COG4134	Bacterial extracellular solute-binding protein
F3113_RS14180	COG4135	transport system, permease component
F3113_RS14185	COG4136	ATPase activity
F3113_RS14190	COG2897	thiosulfate sulfurtransferase activity
F3113_RS14195	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F3113_RS14200	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3113_RS14205	COG0494	nUDIX hydrolase
F3113_RS14220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F3113_RS14230	COG0778	Nitroreductase
F3113_RS14235	COG0616	signal peptide processing
F3113_RS14240	COG0252	asparaginase activity
F3113_RS14245	COG1335	isochorismatase
F3113_RS14250	COG2814	Major facilitator Superfamily
F3113_RS14255	COG1349	DNA-binding transcription factor activity
F3113_RS14260	COG0667	Aldo Keto reductase
F3113_RS14265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3113_RS14270	COG0191	fructose-bisphosphate aldolase activity
F3113_RS14275	COG1063	alcohol dehydrogenase
F3113_RS14280	COG2271	Major facilitator Superfamily
F3113_RS14285	COG1063	alcohol dehydrogenase
F3113_RS14300	COG3139	Protein of unknown function (DUF1315)
F3113_RS14320	COG0656	L-ascorbic acid biosynthetic process
F3113_RS14325	COG3713	MltA-interacting MipA family protein
F3113_RS14330	COG2766	serine protein kinase
F3113_RS14340	COG2226	methyltransferase
F3113_RS14345	COG2199	diguanylate cyclase activity
F3113_RS14350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F3113_RS14360	COG2207	Transcriptional regulator
F3113_RS14365	COG2807	transmembrane transport
F3113_RS14370	COG0504	CTP synthase activity
F3113_RS14375	COG3189	MarR family transcriptional regulator
F3113_RS14380	COG3042	response to heat
F3113_RS14385	COG2199	diguanylate cyclase activity
F3113_RS14385	COG2203	Gaf domain
F3113_RS14400	COG2261	transglycosylase associated protein
F3113_RS14405	COG3383	formate dehydrogenase (NAD+) activity
F3113_RS14420	COG3615	Tellurite resistance protein tehB
F3113_RS14430	COG3443	Belongs to the bacterial solute-binding protein 9 family
F3113_RS14435	COG1124	(ABC) transporter
F3113_RS14445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3113_RS14450	COG0601	transmembrane transport
F3113_RS14455	COG0747	negative chemotaxis
F3113_RS14460	COG4771	TonB-dependent receptor
F3113_RS14525	COG0431	NADPH-dependent FMN reductase
F3113_RS14530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F3113_RS14545	COG0538	isocitrate dehydrogenase activity
F3113_RS14575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F3113_RS14580	COG2135	peptidase activity
F3113_RS14600	COG3436	PFAM IS66 Orf2 family protein
F3113_RS14615	COG3272	Protein of unknown function (DUF1722)
F3113_RS14635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3113_RS14650	COG0300	oxidoreductase activity
F3113_RS14660	COG0789	Transcriptional regulator
F3113_RS14750	COG0616	signal peptide processing
F3113_RS14765	COG4626	Terminase
F3113_RS14765	COG1802	Transcriptional regulator
F3113_RS14825	COG3772	lysozyme
F3113_RS14855	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
F3113_RS14890	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F3113_RS14940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3113_RS14950	COG0582	viral genome integration into host DNA
F3113_RS14965	COG2850	peptidyl-arginine hydroxylation
F3113_RS14985	COG1177	transmembrane transport
F3113_RS14995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F3113_RS15005	COG4591	ABC-type transport system involved in lipoprotein release permease component
F3113_RS15010	COG1136	(ABC) transporter
F3113_RS15015	COG4591	ABC-type transport system involved in lipoprotein release permease component
F3113_RS15020	COG4763	Acyl-transferase
F3113_RS15025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F3113_RS15030	COG1388	LysM domain
F3113_RS15030	COG1376	ErfK ybiS ycfS ynhG family protein
F3113_RS15040	COG1309	transcriptional regulator
F3113_RS15050	COG3134	Outer membrane lipoprotein
F3113_RS15055	COG1252	NADH dehydrogenase
F3113_RS15080	COG5633	Lipoprotein
F3113_RS15085	COG0537	adenosine 5'-monophosphoramidase activity
F3113_RS15090	COG0583	DNA-binding transcription factor activity
F3113_RS15100	COG0309	Hydrogenase expression formation protein (HypE)
F3113_RS15105	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
F3113_RS15110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3113_RS15115	COG2223	nitrite transmembrane transporter activity
F3113_RS15125	COG0534	Mate efflux family protein
F3113_RS15135	COG0583	DNA-binding transcription factor activity
F3113_RS15155	COG1027	Aspartate ammonia-lyase
F3113_RS15160	COG0583	DNA-binding transcription factor activity
F3113_RS15180	COG1595	DNA-templated transcription, initiation
F3113_RS15185	COG3712	iron ion homeostasis
F3113_RS15190	COG4772	TonB-dependent receptor
F3113_RS15195	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
F3113_RS15200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3113_RS15205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3113_RS15210	COG1120	ATPase activity
F3113_RS15235	COG0477	Major facilitator Superfamily
F3113_RS15240	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F3113_RS15255	COG0084	hydrolase, TatD family'
F3113_RS15260	COG0470	DNA polymerase III
F3113_RS15270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F3113_RS15275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3113_RS15280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3113_RS15315	COG1399	metal-binding, possibly nucleic acid-binding protein
F3113_RS15325	COG0564	pseudouridine synthase activity
F3113_RS15330	COG1530	ribonuclease E activity
F3113_RS15335	COG0583	DNA-binding transcription factor activity
F3113_RS15340	COG2814	Major facilitator Superfamily
F3113_RS15370	COG4786	Flagellar basal body rod
F3113_RS15375	COG4787	bacterial-type flagellum-dependent cell motility
F3113_RS15390	COG1558	bacterial-type flagellum-dependent cell motility
F3113_RS15430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3113_RS15470	COG3038	cytochrome b561
F3113_RS15485	COG1560	Kdo2-lipid A biosynthetic process
F3113_RS15495	COG2199	diguanylate cyclase activity
F3113_RS15505	COG5645	(Lipo)protein
F3113_RS15590	COG3381	protein complex oligomerization
F3113_RS15625	COG2962	Rard protein
F3113_RS15630	COG2990	Protein conserved in bacteria
F3113_RS15635	COG1702	phosphate starvation-inducible protein PhoH
F3113_RS15655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3113_RS15660	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F3113_RS15660	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F3113_RS15660	COG0506	proline dehydrogenase activity
F3113_RS15665	COG3755	Protein conserved in bacteria
F3113_RS15670	COG1309	transcriptional regulator
F3113_RS15680	COG3729	General stress protein
F3113_RS15735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F3113_RS15755	COG0640	Transcriptional regulator
F3113_RS15775	COG1136	(ABC) transporter
F3113_RS15775	COG0577	efflux transmembrane transporter activity
F3113_RS15785	COG1136	(ABC) transporter
F3113_RS15785	COG0577	efflux transmembrane transporter activity
F3113_RS15800	COG0672	)-iron permease
F3113_RS15810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3113_RS15815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3113_RS15815	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F3113_RS15865	COG0813	purine-nucleoside phosphorylase activity
F3113_RS15880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3113_RS15885	COG1120	ATPase activity
F3113_RS15895	COG0723	plastoquinol--plastocyanin reductase activity
F3113_RS15900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F3113_RS15900	COG2857	Cytochrome c1
F3113_RS15920	COG0670	Belongs to the BI1 family
F3113_RS15945	COG1832	CoA-binding protein
F3113_RS15960	COG0210	DNA helicase
F3113_RS15965	COG3304	Inner membrane component domain
F3113_RS15970	COG1289	transmembrane transporter activity
F3113_RS15975	COG3070	regulator of competence-specific genes
F3113_RS15995	COG1067	ATP-dependent peptidase activity
F3113_RS16005	COG3130	regulation of translation
F3113_RS16010	COG3009	Protein conserved in bacteria
F3113_RS16015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F3113_RS16015	COG3008	intermembrane lipid transfer
F3113_RS16020	COG2995	paraquat-inducible protein a
F3113_RS16025	COG0488	(ABC) transporter
F3113_RS16035	COG3217	Mosc domain protein beta barrel domain protein
F3113_RS16035	COG0633	Ferredoxin
F3113_RS16050	COG0431	NADPH-dependent FMN reductase
F3113_RS16055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3113_RS16065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3113_RS16070	COG1116	anion transmembrane transporter activity
F3113_RS16075	COG0308	aminopeptidase N
F3113_RS16205	COG4695	Portal protein
F3113_RS16215	COG1802	Transcriptional regulator
F3113_RS16215	COG4626	Terminase
F3113_RS16260	COG3179	chitinase
F3113_RS16380	COG0582	viral genome integration into host DNA
F3113_RS16400	COG1448	Aminotransferase
F3113_RS16405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3113_RS16410	COG3108	Peptidase M15
F3113_RS16415	COG2989	Protein conserved in bacteria
F3113_RS16425	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
F3113_RS16435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3113_RS16440	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F3113_RS16445	COG3173	Aminoglycoside phosphotransferase
F3113_RS16460	COG3214	Protein conserved in bacteria
F3113_RS16475	COG0658	competence protein
F3113_RS16475	COG2333	competence protein COMEC
F3113_RS16480	COG0776	regulation of translation
F3113_RS16485	COG0539	negative regulation of cytoplasmic translation
F3113_RS16495	COG0501	Belongs to the peptidase M48B family
F3113_RS16510	COG2323	membrane
F3113_RS16515	COG1944	ATP diphosphatase activity
F3113_RS16520	COG2116	formate transmembrane transporter activity
F3113_RS16525	COG1882	Formate acetyltransferase
F3113_RS16660	COG4695	Portal protein
F3113_RS16715	COG4974	Belongs to the 'phage' integrase family
F3113_RS16720	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F3113_RS16725	COG0531	amino acid
F3113_RS16735	COG1335	isochorismatase
F3113_RS16740	COG3302	dmso reductase anchor subunit
F3113_RS16745	COG0437	4 iron, 4 sulfur cluster binding
F3113_RS16750	COG0243	molybdopterin cofactor binding
F3113_RS16760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F3113_RS16770	COG1674	ftsk spoiiie
F3113_RS16770	COG1178	ABC-type Fe3 transport system permease component
F3113_RS16780	COG0492	ferredoxin-NADP+ reductase activity
F3113_RS16785	COG4988	ABC transporter
F3113_RS16790	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F3113_RS16805	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F3113_RS16810	COG0583	DNA-binding transcription factor activity
F3113_RS16820	COG1335	isochorismatase
F3113_RS16840	COG1177	transmembrane transport
F3113_RS16845	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3113_RS16850	COG3842	ATPase activity
F3113_RS16855	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3113_RS16910	COG0583	DNA-binding transcription factor activity
F3113_RS16915	COG3226	Transcriptional regulator
F3113_RS16920	COG0738	Major facilitator superfamily
F3113_RS16925	COG0561	phosphatase activity
F3113_RS16935	COG2814	Major facilitator Superfamily
F3113_RS16940	COG0671	phosphoesterase, PA-phosphatase related
F3113_RS16945	COG1349	DNA-binding transcription factor activity
F3113_RS16950	COG1686	Belongs to the peptidase S11 family
F3113_RS16955	COG0625	glutathione transferase activity
F3113_RS16960	COG2133	pyrroloquinoline quinone binding
F3113_RS17050	COG1446	asparaginase
F3113_RS17060	COG0303	'Molybdopterin
F3113_RS17065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F3113_RS17070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F3113_RS17075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F3113_RS17080	COG1882	Formate acetyltransferase
F3113_RS17085	COG0561	phosphatase activity
F3113_RS17095	COG0488	(ABC) transporter
F3113_RS17100	COG1376	ErfK ybiS ycfS ynhG family protein
F3113_RS17105	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F3113_RS17120	COG2194	sulfuric ester hydrolase activity
F3113_RS17125	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F3113_RS17140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3113_RS17145	COG0765	amino acid transport
F3113_RS17150	COG1126	abc transporter atp-binding protein
F3113_RS17155	COG0668	transmembrane transport
F3113_RS17170	COG4774	siderophore transport
F3113_RS17180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F3113_RS17190	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F3113_RS17195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F3113_RS17205	COG0471	metal ion transport
F3113_RS17215	COG2188	Transcriptional regulator
F3113_RS17220	COG0513	Belongs to the DEAD box helicase family
F3113_RS17225	COG1309	transcriptional regulator
F3113_RS17235	COG1131	(ABC) transporter
F3113_RS17240	COG0842	Transport permease protein
F3113_RS17245	COG0842	Transport permease protein
F3113_RS17255	COG3568	Endonuclease Exonuclease Phosphatase
F3113_RS17260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3113_RS17265	COG0392	lysyltransferase activity
F3113_RS17270	COG0670	Belongs to the BI1 family
F3113_RS17275	COG0314	molybdopterin synthase activity
F3113_RS17280	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
F3113_RS17290	COG0521	Mo-molybdopterin cofactor biosynthetic process
F3113_RS17315	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F3113_RS17335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3113_RS17340	COG1881	PFAM PEBP family protein
F3113_RS17370	COG4677	pectinesterase activity
F3113_RS17385	COG0561	phosphatase activity
F3113_RS17395	COG4149	molybdate abc transporter
F3113_RS17400	COG0725	ABC transporter, periplasmic molybdate-binding protein
F3113_RS17410	COG2005	Transcriptional regulator
F3113_RS17410	COG3585	molybdate ion transport
F3113_RS17415	COG1119	ATPase activity
F3113_RS17420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F3113_RS17425	COG1085	galactose-1-phosphate uridylyltransferase
F3113_RS17435	COG2017	converts alpha-aldose to the beta-anomer
F3113_RS17445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F3113_RS17455	COG1230	cation diffusion facilitator family transporter
F3113_RS17460	COG3201	nicotinamide mononucleotide transporter
F3113_RS17490	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
F3113_RS17495	COG2885	chlorophyll binding
F3113_RS17505	COG3064	Membrane
F3113_RS17510	COG0848	biopolymer transport protein
F3113_RS17515	COG0811	peptide transport
F3113_RS17520	COG0824	Thioesterase
F3113_RS17525	COG3790	cyd operon protein YbgE
F3113_RS17530	COG4890	Cyd operon protein YbgT
F3113_RS17535	COG1294	oxidase, subunit
F3113_RS17540	COG1271	oxidase subunit
F3113_RS17545	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F3113_RS17555	COG4865	methylaspartate mutase activity
F3113_RS17560	COG3799	methylaspartate ammonia-lyase activity
F3113_RS17575	COG1301	dicarboxylic acid transport
F3113_RS17585	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F3113_RS17585	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F3113_RS17595	COG0583	DNA-binding transcription factor activity
F3113_RS17600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F3113_RS17600	COG1648	precorrin-2 dehydrogenase activity
F3113_RS17610	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F3113_RS17620	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3113_RS17625	COG0567	Dehydrogenase, E1 component
F3113_RS17630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F3113_RS17635	COG1053	succinate dehydrogenase
F3113_RS17640	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F3113_RS17645	COG2009	succinate dehydrogenase
F3113_RS17670	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
F3113_RS17675	COG3180	Ammonia monooxygenase
F3113_RS17705	COG1984	allophanate hydrolase subunit 2
F3113_RS17710	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F3113_RS17725	COG5464	transposase or invertase
F3113_RS17735	COG3272	Protein of unknown function (DUF1722)
F3113_RS17765	COG2205	protein histidine kinase activity
F3113_RS17770	COG0745	RESPONSE REGULATOR receiver
F3113_RS17775	COG0033	Phosphoglucomutase
F3113_RS17780	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
F3113_RS17785	COG0596	Alpha beta hydrolase
F3113_RS17795	COG0716	FMN binding
F3113_RS17805	COG0735	belongs to the Fur family
F3113_RS17810	COG0583	DNA-binding transcription factor activity
F3113_RS17815	COG1053	succinate dehydrogenase
F3113_RS17845	COG1263	PTS System
F3113_RS17845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3113_RS17845	COG2190	(PTS) system
F3113_RS17855	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F3113_RS17860	COG1846	Transcriptional regulator
F3113_RS17860	COG1940	carbohydrate kinase activity
F3113_RS17865	COG0647	UMP catabolic process
F3113_RS17870	COG0367	asparagine synthase
F3113_RS17890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3113_RS17900	COG1702	phosphate starvation-inducible protein PhoH
F3113_RS17910	COG4535	Mg2 and Co2 transporter CorC
F3113_RS17925	COG0765	amino acid transport
F3113_RS17930	COG0765	amino acid transport
F3113_RS17935	COG1126	abc transporter atp-binding protein
F3113_RS17945	COG2888	peptidyl-tyrosine sulfation
F3113_RS17960	COG1466	dna polymerase III delta subunit
F3113_RS17970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F3113_RS17980	COG0799	negative regulation of ribosome biogenesis
F3113_RS17990	COG0768	penicillin binding
F3113_RS17995	COG0772	Belongs to the SEDS family
F3113_RS18000	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F3113_RS18005	COG1686	Belongs to the peptidase S11 family
F3113_RS18030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3113_RS18050	COG3069	C4-dicarboxylate transmembrane transporter activity
F3113_RS18065	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
F3113_RS18075	COG2301	Belongs to the HpcH HpaI aldolase family
F3113_RS18080	COG3051	citrate lyase alpha subunit
F3113_RS18095	COG0471	metal ion transport
F3113_RS18100	COG3719	Belongs to the RNase T2 family
F3113_RS18115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3113_RS18145	COG3634	alkyl hydroperoxide reductase activity
F3113_RS18155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3113_RS18160	COG0583	DNA-binding transcription factor activity
F3113_RS18165	COG3969	phosphoadenosine phosphosulfate
F3113_RS18170	COG1475	DNA binding
F3113_RS18175	COG0436	Aminotransferase
F3113_RS18180	COG0371	Dehydrogenase
F3113_RS18185	COG2879	small protein
F3113_RS18190	COG1966	Carbon starvation protein
F3113_RS18200	COG1028	Short-chain dehydrogenase reductase Sdr
F3113_RS18205	COG1535	isochorismatase
F3113_RS18205	COG3433	isochorismatase activity
F3113_RS18210	COG1021	2,3-dihydroxybenzoate-AMP ligase
F3113_RS18215	COG1169	isochorismate synthase
F3113_RS18220	COG4592	Periplasmic binding protein
F3113_RS18230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3113_RS18235	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3113_RS18240	COG1120	ATPase activity
F3113_RS18245	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
F3113_RS18250	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F3113_RS18250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3113_RS18255	COG3251	PFAM MbtH domain protein
F3113_RS18260	COG2382	esterase
F3113_RS18265	COG4771	TonB-dependent receptor
F3113_RS18305	COG2315	Protein conserved in bacteria
F3113_RS18315	COG0668	transmembrane transport
F3113_RS18335	COG2211	Major facilitator Superfamily
F3113_RS18340	COG1113	amino acid transport
F3113_RS18360	COG5001	Diguanylate cyclase
F3113_RS18360	COG3300	MHYT domain
F3113_RS18375	COG3059	membrane
F3113_RS18385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3113_RS18390	COG2207	Transcriptional regulator
F3113_RS18395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3113_RS18400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3113_RS18410	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3113_RS18415	COG1538	Outer membrane efflux protein
F3113_RS18420	COG0745	RESPONSE REGULATOR receiver
F3113_RS18425	COG5002	protein histidine kinase activity
F3113_RS18440	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F3113_RS18440	COG0321	lipoyl(octanoyl) transferase activity
F3113_RS18445	COG0243	molybdopterin cofactor binding
F3113_RS18470	COG3005	denitrification pathway
F3113_RS18475	COG0745	RESPONSE REGULATOR receiver
F3113_RS18480	COG1879	ABC-type sugar transport system periplasmic component
F3113_RS18485	COG0784	Response regulator, receiver
F3113_RS18485	COG2198	Histidine kinase
F3113_RS18485	COG2205	protein histidine kinase activity
F3113_RS18555	COG2501	S4 domain
F3113_RS18560	COG1988	membrane-bound metal-dependent
F3113_RS18570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F3113_RS18580	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F3113_RS18585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F3113_RS18590	COG0549	Belongs to the carbamate kinase family
F3113_RS18600	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F3113_RS18605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F3113_RS18610	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F3113_RS18615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3113_RS18620	COG3257	ureidoglycine aminohydrolase activity
F3113_RS18625	COG1929	Belongs to the glycerate kinase type-1 family
F3113_RS18630	COG2233	PERMEase
F3113_RS18650	COG2084	Dehydrogenase
F3113_RS18655	COG3622	Belongs to the hyi family
F3113_RS18660	COG3960	tartronate-semialdehyde synthase activity
F3113_RS18695	COG1464	Belongs to the NlpA lipoprotein family
F3113_RS18700	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F3113_RS18705	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F3113_RS18710	COG4181	ATPase activity
F3113_RS18715	COG2755	lipolytic protein G-D-S-L family
F3113_RS18720	COG0300	oxidoreductase activity
F3113_RS18725	COG3118	belongs to the thioredoxin family
F3113_RS18730	COG0390	transport system, permease component
F3113_RS18735	COG4619	ABC transporter
F3113_RS18740	COG0330	HflC and HflK could
F3113_RS18745	COG1585	Membrane protein implicated in regulation of membrane protease activity
F3113_RS18765	COG4771	TonB-dependent receptor
F3113_RS18770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3113_RS18780	COG3721	Heme iron utilization protein
F3113_RS18790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3113_RS18800	COG2217	Heavy metal translocating P-type atpase
F3113_RS18805	COG3735	TraB family
F3113_RS18810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F3113_RS18820	COG2223	nitrite transmembrane transporter activity
F3113_RS18825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3113_RS18825	COG4651	solute:proton antiporter activity
F3113_RS18830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3113_RS18875	COG2832	Protein of unknown function (DUF454)
F3113_RS18880	COG3923	Primosomal replication protein n
F3113_RS18890	COG1196	nuclear chromosome segregation
F3113_RS18890	COG3264	Mechanosensitive ion channel
F3113_RS18895	COG1309	transcriptional regulator
F3113_RS18900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3113_RS18905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3113_RS18920	COG0110	maltose O-acetyltransferase activity
F3113_RS18940	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F3113_RS18945	COG5507	3-demethylubiquinone-9 3-methyltransferase
F3113_RS18950	COG2364	Membrane
F3113_RS18955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3113_RS18975	COG3695	enzyme binding
F3113_RS18980	COG3126	Type III secretion system lipoprotein chaperone (YscW)
F3113_RS18985	COG1946	Acyl-CoA thioesterase
F3113_RS18990	COG0004	ammonium transporteR
F3113_RS18995	COG0347	Belongs to the P(II) protein family
F3113_RS19000	COG1132	(ABC) transporter
F3113_RS19005	COG1132	(ABC) transporter
F3113_RS19010	COG1522	sequence-specific DNA binding
F3113_RS19025	COG4533	DNA binding
F3113_RS19035	COG0824	Thioesterase
F3113_RS19040	COG1555	photosystem II stabilization
F3113_RS19045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F3113_RS19050	COG0776	regulation of translation
F3113_RS19055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F3113_RS19075	COG0271	Belongs to the BolA IbaG family
F3113_RS19080	COG3056	Lipoprotein
F3113_RS19085	COG2223	nitrite transmembrane transporter activity
F3113_RS19090	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F3113_RS19095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3113_RS19100	COG1845	cytochrome c oxidase, subunit III
F3113_RS19105	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F3113_RS19115	COG2814	Major facilitator Superfamily
F3113_RS19150	COG0142	geranyltranstransferase activity
F3113_RS19160	COG0667	Aldo Keto reductase
F3113_RS19165	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F3113_RS19170	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F3113_RS19185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3113_RS19185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3113_RS19195	COG4238	major outer membrane lipoprotein
F3113_RS19215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F3113_RS19220	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F3113_RS19225	COG1862	Preprotein translocase
F3113_RS19235	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F3113_RS19245	COG0450	alkyl hydroperoxide reductase
F3113_RS19250	COG1574	metal-dependent hydrolase with the TIM-barrel fold
F3113_RS19260	COG1335	isochorismatase
F3113_RS19265	COG0583	DNA-binding transcription factor activity
F3113_RS19270	COG0366	Alpha amylase catalytic
F3113_RS19285	COG5002	protein histidine kinase activity
F3113_RS19295	COG0420	3'-5' exonuclease activity
F3113_RS19300	COG0419	ATPase involved in DNA repair
F3113_RS19305	COG2814	Major facilitator Superfamily
F3113_RS19310	COG1940	carbohydrate kinase activity
F3113_RS19325	COG4126	flavin adenine dinucleotide binding
F3113_RS19345	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3113_RS19350	COG3706	GGDEF domain
F3113_RS19360	COG1785	Belongs to the alkaline phosphatase family
F3113_RS19375	COG1181	Belongs to the D-alanine--D-alanine ligase family
F3113_RS19395	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F3113_RS19400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3113_RS19405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3113_RS19415	COG0113	porphobilinogen synthase activity
F3113_RS19420	COG2175	clavaminate synthase activity
F3113_RS19425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3113_RS19430	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F3113_RS19435	COG4521	taurine ABC transporter
F3113_RS19450	COG2271	Major facilitator Superfamily
F3113_RS19455	COG1840	ABC-type Fe3 transport system, periplasmic component
F3113_RS19465	COG3842	ATPase activity
F3113_RS19470	COG2040	homocysteine
F3113_RS19475	COG0833	amino acid
F3113_RS19480	COG2814	Major facilitator Superfamily
F3113_RS19515	COG1414	Transcriptional regulator
F3113_RS19545	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F3113_RS19560	COG1609	Transcriptional regulator
F3113_RS19575	COG0110	maltose O-acetyltransferase activity
F3113_RS19585	COG2079	MmgE PrpD family protein
F3113_RS19590	COG0372	Belongs to the citrate synthase family
F3113_RS19600	COG3829	transcription factor binding
F3113_RS19610	COG1280	lysine exporter protein (LysE YggA)
F3113_RS19615	COG3706	GGDEF domain
F3113_RS19620	COG0348	domain, Protein
F3113_RS19625	COG1737	Transcriptional regulator
F3113_RS19635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3113_RS19640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3113_RS19645	COG1120	ATPase activity
F3113_RS19650	COG4774	siderophore transport
F3113_RS19670	COG0583	DNA-binding transcription factor activity
F3113_RS19690	COG3069	C4-dicarboxylate transmembrane transporter activity
F3113_RS19695	COG2195	Cleaves the N-terminal amino acid of tripeptides
F3113_RS19705	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
F3113_RS19710	COG0693	protein deglycase activity
F3113_RS19715	COG2957	Belongs to the agmatine deiminase family
F3113_RS19720	COG2200	EAL domain
F3113_RS19730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3113_RS19735	COG0531	amino acid
F3113_RS19740	COG0174	glutamine synthetase
F3113_RS19745	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F3113_RS19750	COG1917	Cupin 2, conserved barrel domain protein
F3113_RS19750	COG1396	sequence-specific DNA binding
F3113_RS19755	COG1012	belongs to the aldehyde dehydrogenase family
F3113_RS19760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3113_RS19775	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
F3113_RS19780	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F3113_RS19785	COG1999	signal sequence binding
F3113_RS19790	COG1773	rubredoxin
F3113_RS19795	COG1271	oxidase subunit
F3113_RS19800	COG1294	oxidase, subunit
F3113_RS19830	COG1757	Na H antiporter
F3113_RS19835	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F3113_RS19845	COG0582	viral genome integration into host DNA
F3113_RS19880	COG4372	Transposase
F3113_RS19885	COG3436	PFAM IS66 Orf2 family protein
F3113_RS19930	COG2826	transposase and inactivated derivatives, IS30 family
F3113_RS19950	COG3596	GTP binding
F3113_RS19960	COG2378	regulation of single-species biofilm formation
F3113_RS19990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F3113_RS20005	COG2003	Belongs to the UPF0758 family
F3113_RS20150	COG1783	phage Terminase large subunit
F3113_RS20175	COG3179	chitinase
F3113_RS20205	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
F3113_RS20245	COG0305	Participates in initiation and elongation during chromosome replication
F3113_RS20275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F3113_RS20305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3113_RS20315	COG0629	single-stranded DNA binding
F3113_RS20325	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F3113_RS20340	COG0582	viral genome integration into host DNA
F3113_RS20355	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F3113_RS20395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3113_RS20405	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F3113_RS20430	COG2195	Cleaves the N-terminal amino acid of tripeptides
F3113_RS20455	COG0791	NLP P60 protein
F3113_RS20460	COG3034	peptidoglycan biosynthetic process
F3113_RS20465	COG0121	glutamine amidotransferase
F3113_RS20475	COG1960	acyl-CoA dehydrogenase activity
F3113_RS20480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3113_RS20490	COG2200	EAL domain
F3113_RS20505	COG3539	Fimbrial protein
F3113_RS20515	COG3121	Chaperone
F3113_RS20520	COG3188	usher protein
F3113_RS20530	COG3539	Fimbrial protein
F3113_RS20535	COG0745	RESPONSE REGULATOR receiver
F3113_RS20550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3113_RS20560	COG2226	methyltransferase
F3113_RS20570	COG1388	LysM domain
F3113_RS20570	COG0741	lytic transglycosylase activity
F3113_RS20575	COG2226	methyltransferase
F3113_RS20585	COG2814	Major facilitator Superfamily
F3113_RS20590	COG0583	DNA-binding transcription factor activity
F3113_RS20625	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F3113_RS20635	COG2011	ABC-type metal ion transport system permease component
F3113_RS20640	COG1464	Belongs to the NlpA lipoprotein family
F3113_RS20650	COG1720	tRNA m6t6A37 methyltransferase activity
F3113_RS20660	COG3015	lipoprotein NlpE involved in copper resistance
F3113_RS20665	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
F3113_RS20680	COG4568	rho-dependent transcription termination
F3113_RS20690	COG0346	lactoylglutathione lyase activity
F3113_RS20695	COG1982	Orn Lys Arg decarboxylase major
F3113_RS20730	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3113_RS20735	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
F3113_RS20750	COG0575	Belongs to the CDS family
F3113_RS20760	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F3113_RS20805	COG3835	regulator
F3113_RS20830	COG2860	membrane
F3113_RS20855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3113_RS20860	COG1120	ATPase activity
F3113_RS20865	COG4774	siderophore transport
F3113_RS20870	COG3539	Fimbrial protein
F3113_RS20875	COG3188	usher protein
F3113_RS20880	COG3121	Chaperone
F3113_RS20890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3113_RS20895	COG1643	Atp-dependent helicase
F3113_RS20900	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F3113_RS20920	COG0617	tRNA 3'-terminal CCA addition
F3113_RS20925	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F3113_RS20945	COG0726	polysaccharide deacetylase
F3113_RS20950	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3113_RS20955	COG0842	Transport permease protein
F3113_RS20960	COG1131	(ABC) transporter
F3113_RS20965	COG0288	reversible hydration of carbon dioxide
F3113_RS20970	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
F3113_RS21000	COG3064	Membrane
F3113_RS21015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3113_RS21020	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3113_RS21025	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F3113_RS21040	COG2211	Major facilitator Superfamily
F3113_RS21045	COG3940	Belongs to the glycosyl hydrolase 43 family
F3113_RS21050	COG3725	Membrane protein required for beta-lactamase induction
F3113_RS21065	COG4969	Belongs to the N-Me-Phe pilin family
F3113_RS21070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F3113_RS21075	COG1459	type II secretion system
F3113_RS21085	COG0237	dephospho-CoA kinase activity
F3113_RS21100	COG0494	nUDIX hydrolase
F3113_RS21120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F3113_RS21125	COG0849	cell division
F3113_RS21135	COG1181	Belongs to the D-alanine--D-alanine ligase family
F3113_RS21150	COG0772	Belongs to the SEDS family
F3113_RS21155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F3113_RS21165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F3113_RS21170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F3113_RS21175	COG0768	penicillin binding
F3113_RS21205	COG0028	Belongs to the TPP enzyme family
F3113_RS21240	COG1609	Transcriptional regulator
F3113_RS21250	COG1028	Short-chain dehydrogenase reductase Sdr
F3113_RS21255	COG2814	Major facilitator Superfamily
F3113_RS21275	COG1178	ABC-type Fe3 transport system permease component
F3113_RS21285	COG0586	Pfam SNARE associated Golgi protein
F3113_RS21305	COG0235	Class ii aldolase
F3113_RS21315	COG0417	DNA replication proofreading
F3113_RS21325	COG0564	pseudouridine synthase activity
F3113_RS21335	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F3113_RS21385	COG2271	Major facilitator Superfamily
F3113_RS21395	COG0644	oxidoreductase
F3113_RS21450	COG0505	Belongs to the CarA family
F3113_RS21470	COG1047	Peptidyl-prolyl cis-trans
F3113_RS21485	COG0196	riboflavin kinase activity
F3113_RS21505	COG0583	DNA-binding transcription factor activity
F3113_RS21520	COG0641	radical SAM
F3113_RS21525	COG3119	arylsulfatase activity
F3113_RS21540	COG0443	Heat shock 70 kDa protein
F3113_RS21550	COG4735	regulation of single-species biofilm formation
F3113_RS21555	COG1584	GPR1 FUN34 yaaH family protein
F3113_RS21565	COG0521	Mo-molybdopterin cofactor biosynthetic process
F3113_RS21575	COG1115	amino acid carrier protein
F3113_RS21585	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F3113_RS21595	COG0460	homoserine dehydrogenase
F3113_RS21595	COG0527	aspartate kinase activity
F3113_RS21605	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
F3113_RS21615	COG0745	RESPONSE REGULATOR receiver
F3113_RS21620	COG4452	Inner membrane protein CreD
F3113_RS21625	COG2205	protein histidine kinase activity
F3113_RS21630	COG0745	RESPONSE REGULATOR receiver
F3113_RS21635	COG3045	CreA protein
F3113_RS21640	COG3708	Transcriptional regulator
F3113_RS21640	COG2207	Transcriptional regulator
F3113_RS21660	COG0741	lytic transglycosylase activity
F3113_RS21670	COG0488	(ABC) transporter
F3113_RS21685	COG0560	Phosphoserine phosphatase
F3113_RS21690	COG3726	membrane protein affecting hemolysin expression
F3113_RS21715	COG2271	Major facilitator Superfamily
F3113_RS21720	COG1802	Transcriptional regulator
F3113_RS21725	COG1063	alcohol dehydrogenase
F3113_RS21745	COG1484	DNA-dependent DNA replication
F3113_RS21760	COG2966	Psort location CytoplasmicMembrane, score
F3113_RS21765	COG2197	response regulator
F3113_RS21770	COG2197	response regulator
F3113_RS21775	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F3113_RS21780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3113_RS21785	COG4114	ferric iron reductase
F3113_RS21790	COG3706	GGDEF domain
F3113_RS21810	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
F3113_RS21815	COG0456	acetyltransferase
F3113_RS21820	COG1011	Hydrolase
F3113_RS21830	COG2823	Periplasmic or secreted lipoprotein
F3113_RS21835	COG5487	UPF0391 membrane protein
F3113_RS21840	COG4667	esterase of the alpha-beta hydrolase superfamily
F3113_RS21845	COG0084	hydrolase, TatD family'
F3113_RS21850	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F3113_RS21855	COG1328	CTP reductase activity
F3113_RS21905	COG0582	viral genome integration into host DNA
F3113_RS21915	COG1064	alcohol dehydrogenase
F3113_RS21920	COG0433	COG0433 Predicted ATPase
F3113_RS21925	COG0795	lipopolysaccharide-transporting ATPase activity
F3113_RS21930	COG0795	lipopolysaccharide-transporting ATPase activity
F3113_RS21940	COG2927	DNA polymerase III (CHI subunit)
F3113_RS21945	COG0525	valine-tRNA ligase activity
F3113_RS21975	COG2731	YhcH YjgK YiaL family protein
F3113_RS21980	COG2235	arginine
F3113_RS21990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F3113_RS21995	COG1288	antiporter activity
F3113_RS22000	COG1438	arginine binding
F3113_RS22045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3113_RS22060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3113_RS22060	COG1263	PTS System
F3113_RS22065	COG0366	Alpha amylase catalytic
F3113_RS22075	COG1737	Transcriptional regulator
F3113_RS22080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS22085	COG0383	alpha-mannosidase activity
F3113_RS22090	COG0366	Alpha amylase catalytic
F3113_RS22095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS22095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3113_RS22095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS22110	COG2026	Addiction module toxin, RelE StbE family
F3113_RS22115	COG3077	Addiction module antitoxin, RelB DinJ family
F3113_RS22120	COG3711	transcriptional antiterminator
F3113_RS22120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3113_RS22135	COG3964	amidohydrolase
F3113_RS22170	COG0312	modulator of DNA gyrase
F3113_RS22180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F3113_RS22190	COG0840	transmembrane signaling receptor activity
F3113_RS22195	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3113_RS22200	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3113_RS22205	COG1129	ABC transporter
F3113_RS22210	COG1879	ABC-type sugar transport system periplasmic component
F3113_RS22220	COG2105	PFAM AIG2 family protein
F3113_RS22225	COG2911	Protein conserved in bacteria
F3113_RS22230	COG0729	surface antigen
F3113_RS22240	COG1253	flavin adenine dinucleotide binding
F3113_RS22250	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
F3113_RS22255	COG1218	3'(2'),5'-bisphosphate nucleotidase
F3113_RS22265	COG1733	regulation of RNA biosynthetic process
F3113_RS22270	COG0702	epimerase
F3113_RS22280	COG0697	spore germination
F3113_RS22285	COG0840	transmembrane signaling receptor activity
F3113_RS22295	COG1113	amino acid transport
F3113_RS22300	COG0545	Peptidyl-prolyl cis-trans isomerase
F3113_RS22305	COG3061	Opacity-associated protein A
F3113_RS22320	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F3113_RS22335	COG0730	response to heat
F3113_RS22385	COG1073	alpha beta
F3113_RS22390	COG3650	response to hydrogen peroxide
F3113_RS22400	COG1960	acyl-CoA dehydrogenase activity
F3113_RS22405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3113_RS22410	COG0557	exoribonuclease II activity
F3113_RS22425	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
F3113_RS22430	COG0330	HflC and HflK could
F3113_RS22435	COG0330	HflC and HflK could
F3113_RS22440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F3113_RS22445	COG1923	regulation of RNA biosynthetic process
F3113_RS22460	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3113_RS22465	COG0802	atpase or kinase
F3113_RS22470	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F3113_RS22470	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F3113_RS22475	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F3113_RS22500	COG3264	Mechanosensitive ion channel
F3113_RS22500	COG1511	domain protein
F3113_RS22515	COG1053	succinate dehydrogenase
F3113_RS22520	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F3113_RS22575	COG1509	lysine 2,3-aminomutase activity
F3113_RS22600	COG0531	amino acid
F3113_RS22605	COG3030	protein affecting phage T7 exclusion by the F plasmid
F3113_RS22610	COG1027	Aspartate ammonia-lyase
F3113_RS22615	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F3113_RS22630	COG1309	transcriptional regulator
F3113_RS22640	COG0318	PFAM AMP-dependent synthetase and ligase
F3113_RS22670	COG3290	protein histidine kinase activity
F3113_RS22675	COG4565	transcriptional regulatory protein
F3113_RS22680	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F3113_RS22685	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F3113_RS22685	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F3113_RS22690	COG3647	Membrane
F3113_RS22700	COG2211	Major facilitator Superfamily
F3113_RS22705	COG1486	melibiose metabolic process
F3113_RS22710	COG2169	Transcriptional regulator
F3113_RS22715	COG1982	Orn Lys Arg decarboxylase major
F3113_RS22720	COG2207	Transcriptional regulator
F3113_RS22725	COG0531	amino acid
F3113_RS22765	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
F3113_RS22770	COG2824	Alkylphosphonate utilization operon protein PhnA
F3113_RS22775	COG2764	glyoxalase bleomycin resistance protein dioxygenase
F3113_RS22780	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
F3113_RS22785	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
F3113_RS22790	COG3639	organic phosphonate transmembrane transporter activity
F3113_RS22795	COG2188	Transcriptional regulator
F3113_RS22800	COG3624	Phosphonate C-P lyase system protein PhnG
F3113_RS22805	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F3113_RS22810	COG3626	phosphonate metabolism
F3113_RS22815	COG3627	carbon phosphorus lyase activity
F3113_RS22820	COG4107	phosphonate C-P lyase system protein PhnK
F3113_RS22825	COG4778	phosphonate C-P lyase system protein PhnL
F3113_RS22830	COG3454	Phosphonate metabolism
F3113_RS22840	COG0456	acetyltransferase
F3113_RS22845	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F3113_RS22860	COG1129	ABC transporter
F3113_RS22865	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3113_RS22895	COG2015	COG2015, Alkyl sulfatase and related hydrolases
F3113_RS22905	COG1566	PFAM secretion protein HlyD family protein
F3113_RS22910	COG1289	transmembrane transporter activity
F3113_RS22915	COG1538	Outer membrane efflux protein
F3113_RS22925	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F3113_RS22930	COG1301	dicarboxylic acid transport
F3113_RS22935	COG4235	cytochrome complex assembly
F3113_RS22940	COG3088	subunit of a heme lyase
F3113_RS22960	COG3301	Polysulphide reductase, NrfD
F3113_RS22965	COG0437	4 iron, 4 sulfur cluster binding
F3113_RS22970	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
F3113_RS22985	COG3162	membrane
F3113_RS22995	COG1346	cytolysis
F3113_RS23000	COG1380	Effector of murein hydrolase LrgA
F3113_RS23005	COG0583	DNA-binding transcription factor activity
F3113_RS23010	COG1943	Transposase
F3113_RS23015	COG0025	NhaP-type Na H and K H
F3113_RS23020	COG2252	PERMEase
F3113_RS23025	COG0789	Transcriptional regulator
F3113_RS23035	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F3113_RS23045	COG0629	single-stranded DNA binding
F3113_RS23050	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F3113_RS23055	COG2315	Protein conserved in bacteria
F3113_RS23060	COG3700	Belongs to the class B bacterial acid phosphatase family
F3113_RS23065	COG1448	Aminotransferase
F3113_RS23075	COG0305	Participates in initiation and elongation during chromosome replication
F3113_RS23090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3113_RS23155	COG1196	nuclear chromosome segregation
F3113_RS23205	COG1030	water channel activity
F3113_RS23225	COG4220	transposase activity
F3113_RS23240	COG3646	Phage regulatory protein
F3113_RS23260	COG3179	chitinase
F3113_RS23285	COG1403	HNH endonuclease
F3113_RS23310	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
F3113_RS23315	COG4725	Belongs to the MT-A70-like family
F3113_RS23320	COG4626	Terminase
F3113_RS23320	COG1802	Transcriptional regulator
F3113_RS23345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F3113_RS23430	COG0735	belongs to the Fur family
F3113_RS23435	COG3237	CsbD-like
F3113_RS23440	COG0534	Mate efflux family protein
F3113_RS23450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F3113_RS23485	COG2182	Extracellular solute-binding protein
F3113_RS23505	COG1757	Na H antiporter
F3113_RS23510	COG3223	Belongs to the PsiE family
F3113_RS23515	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F3113_RS23520	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3113_RS23545	COG0527	aspartate kinase activity
F3113_RS23550	COG3541	Predicted nucleotidyltransferase
F3113_RS23560	COG4650	regulator
F3113_RS23580	COG0561	phosphatase activity
F3113_RS23595	COG1187	pseudouridine synthase activity
F3113_RS23635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F3113_RS23650	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3113_RS23675	COG1410	methionine synthase
F3113_RS23675	COG0646	methionine synthase
F3113_RS23685	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
F3113_RS23695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F3113_RS23705	COG0456	acetyltransferase
F3113_RS23730	COG0151	Belongs to the GarS family
F3113_RS23740	COG4191	Histidine kinase
F3113_RS23800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F3113_RS23805	COG2104	thiamine diphosphate biosynthetic process
F3113_RS23820	COG1278	Cold shock
F3113_RS23830	COG1447	Phosphotransferase system cellobiose-specific component IIA
F3113_RS23865	COG0250	Participates in transcription elongation, termination and antitermination
F3113_RS23910	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F3113_RS23970	COG0583	DNA-binding transcription factor activity
F3113_RS24005	COG2207	Transcriptional regulator
F3113_RS24015	COG0371	Dehydrogenase
F3113_RS24025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F3113_RS24030	COG0583	DNA-binding transcription factor activity
F3113_RS24040	COG0737	Belongs to the 5'-nucleotidase family
F3113_RS24050	COG0527	aspartate kinase activity
F3113_RS24050	COG0460	homoserine dehydrogenase
F3113_RS24055	COG0626	cystathionine gamma-synthase activity
F3113_RS24065	COG2211	Major facilitator Superfamily
F3113_RS24080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F3113_RS24085	COG1609	Transcriptional regulator
F3113_RS24090	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F3113_RS24105	COG1575	Belongs to the MenA family. Type 1 subfamily
F3113_RS24120	COG3074	FtsZ-dependent cytokinesis
F3113_RS24125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F3113_RS24135	COG1494	fructose-1,6-bisphosphatase
F3113_RS24145	COG3152	Membrane
F3113_RS24160	COG0471	metal ion transport
F3113_RS24190	COG3678	ATP-independent chaperone mediated protein folding
F3113_RS24195	COG0745	RESPONSE REGULATOR receiver
F3113_RS24200	COG2205	protein histidine kinase activity
F3113_RS24205	COG2258	MOSC domain
F3113_RS24210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3113_RS24255	COG1454	alcohol dehydrogenase
F3113_RS24270	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F3113_RS24280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3113_RS24285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS24285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3113_RS24290	COG1363	Peptidase, m42
F3113_RS24295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3113_RS24295	COG3711	transcriptional antiterminator
F3113_RS24325	COG0437	4 iron, 4 sulfur cluster binding
F3113_RS24330	COG2864	formate dehydrogenase
F3113_RS24345	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F3113_RS24355	COG0456	acetyltransferase
F3113_RS24360	COG1490	D-aminoacyl-tRNA deacylase activity
F3113_RS24370	COG1011	Hydrolase
F3113_RS24375	COG1349	DNA-binding transcription factor activity
F3113_RS24380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3113_RS24390	COG3684	Belongs to the aldolase LacD family
F3113_RS24400	COG2017	converts alpha-aldose to the beta-anomer
F3113_RS24405	COG1501	Belongs to the glycosyl hydrolase 31 family
F3113_RS24435	COG3852	Histidine kinase
F3113_RS24440	COG2204	response regulator
F3113_RS24450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3113_RS24470	COG0204	Acyl-transferase
F3113_RS24485	COG3084	Protein conserved in bacteria
F3113_RS24490	COG0746	molybdenum cofactor guanylyltransferase activity
F3113_RS24495	COG1763	Mo-molybdopterin cofactor biosynthetic process
F3113_RS24535	COG1739	Uncharacterized protein family UPF0029
F3113_RS24555	COG1609	Transcriptional regulator
F3113_RS24560	COG1940	carbohydrate kinase activity
F3113_RS24585	COG0805	protein transport
F3113_RS24635	COG0583	DNA-binding transcription factor activity
F3113_RS24640	COG0697	spore germination
F3113_RS24645	COG0561	phosphatase activity
F3113_RS24650	COG2267	carboxylic ester hydrolase activity
F3113_RS24655	COG1280	lysine exporter protein (LysE YggA)
F3113_RS24665	COG1280	lysine exporter protein (LysE YggA)
F3113_RS24700	COG1011	Hydrolase
F3113_RS24745	COG2959	enzyme of heme biosynthesis
F3113_RS24750	COG3071	HemY protein
F3113_RS24795	COG2244	polysaccharide biosynthetic process
F3113_RS24800	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F3113_RS24805	COG0456	acetyltransferase
F3113_RS24810	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F3113_RS24830	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F3113_RS24840	COG3118	belongs to the thioredoxin family
F3113_RS24860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F3113_RS24880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3113_RS24890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3113_RS24895	COG3978	acetolactate synthase activity
F3113_RS24915	COG3085	chromosome segregation
F3113_RS24955	COG2186	Transcriptional regulator
F3113_RS24960	COG0477	Major facilitator Superfamily
F3113_RS24965	COG1609	Transcriptional regulator
F3113_RS24970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3113_RS24975	COG1879	ABC-type sugar transport system periplasmic component
F3113_RS24980	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3113_RS24990	COG1869	D-ribose catabolic process
F3113_RS25015	COG1522	sequence-specific DNA binding
F3113_RS25020	COG0716	FMN binding
F3113_RS25035	COG3312	ion transport
F3113_RS25060	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F3113_RS25070	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F3113_RS25075	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F3113_RS25170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F3113_RS25175	COG0573	inorganic phosphate transmembrane transporter activity
F3113_RS25180	COG0581	inorganic phosphate transmembrane transporter activity
F3113_RS25190	COG0704	Plays a role in the regulation of phosphate uptake
F3113_RS25195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3113_RS25200	COG2252	PERMEase
F3113_RS25205	COG0431	NADPH-dependent FMN reductase
F3113_RS25210	COG2091	lysine biosynthetic process via aminoadipic acid
F3113_RS25245	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F3113_RS25325	COG1349	DNA-binding transcription factor activity
F3113_RS25330	COG2084	Dehydrogenase
F3113_RS25385	COG1192	Involved in chromosome partitioning
F3113_RS25465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F3113_RS25580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3113_RS25710	COG4974	Belongs to the 'phage' integrase family
F3113_RS25850	COG0616	signal peptide processing
F3113_RS25970	COG3300	MHYT domain
F3113_RS25970	COG5001	Diguanylate cyclase
F3113_RS26140	COG1660	Displays ATPase and GTPase activities
F3113_RS26155	COG3173	Aminoglycoside phosphotransferase
F3113_RS26220	COG2186	Transcriptional regulator
F3113_RS26230	COG0246	Mannitol dehydrogenase
F3113_RS26250	COG3250	beta-galactosidase activity
F3113_RS26255	COG1309	transcriptional regulator
F3113_RS26260	COG3039	Transposase
F3113_RS26280	COG1309	transcriptional regulator
F3113_RS26295	COG1136	(ABC) transporter
F3113_RS26330	COG0589	response to stress
F3113_RS26335	COG0659	secondary active sulfate transmembrane transporter activity
F3113_RS26380	COG2826	transposase and inactivated derivatives, IS30 family
F3113_RS26390	COG3436	PFAM IS66 Orf2 family protein
F3113_RS26395	COG2433	Pfam Transposase IS66
F3113_RS26425	COG1121	(ABC) transporter
F3113_RS26460	COG2135	peptidase activity
F3113_RS26510	COG0629	single-stranded DNA binding