locus-tag	class	description
HV164_RS00010	COG0592	DNA-directed DNA polymerase activity
HV164_RS00025	COG0561	phosphatase activity
HV164_RS00035	COG0823	Involved in the tonB-independent uptake of proteins
HV164_RS00040	COG5645	(Lipo)protein
HV164_RS00060	COG2149	membrane
HV164_RS00070	COG0641	radical SAM
HV164_RS00080	COG2610	gluconate transmembrane transporter activity
HV164_RS00085	COG0583	DNA-binding transcription factor activity
HV164_RS00095	COG2814	Major facilitator Superfamily
HV164_RS00115	COG0028	Belongs to the TPP enzyme family
HV164_RS00120	COG0440	acetolactate synthase activity
HV164_RS00125	COG2197	response regulator
HV164_RS00155	COG4580	involved in the transport of maltose and maltodextrins
HV164_RS00160	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV164_RS00165	COG2723	6-phospho-beta-galactosidase activity
HV164_RS00170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV164_RS00170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV164_RS00175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV164_RS00180	COG1609	Transcriptional regulator
HV164_RS00195	COG5464	transposase or invertase
HV164_RS00200	COG1464	Belongs to the NlpA lipoprotein family
HV164_RS00205	COG0697	spore germination
HV164_RS00215	COG1028	Short-chain dehydrogenase reductase Sdr
HV164_RS00230	COG0583	DNA-binding transcription factor activity
HV164_RS00240	COG3539	Fimbrial protein
HV164_RS00260	COG2197	response regulator
HV164_RS00305	COG1501	Belongs to the glycosyl hydrolase 31 family
HV164_RS00310	COG2982	Protein involved in outer membrane biogenesis
HV164_RS00315	COG2233	PERMEase
HV164_RS00320	COG0786	glutamate:sodium symporter activity
HV164_RS00325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HV164_RS00330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV164_RS00335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV164_RS00355	COG2860	membrane
HV164_RS00360	COG1561	YicC-like family, N-terminal region
HV164_RS00370	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HV164_RS00385	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HV164_RS00400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HV164_RS00415	COG1519	Transferase
HV164_RS00420	COG0438	transferase activity, transferring glycosyl groups
HV164_RS00425	COG0515	serine threonine protein kinase
HV164_RS00430	COG1442	glycosyl transferase family 8
HV164_RS00445	COG0859	PFAM glycosyl transferase family 9
HV164_RS00450	COG1215	transferase activity, transferring glycosyl groups
HV164_RS00455	COG3307	-O-antigen
HV164_RS00465	COG0859	PFAM glycosyl transferase family 9
HV164_RS00475	COG0156	8-amino-7-oxononanoate synthase activity
HV164_RS00485	COG1216	Glycosyl transferase, family 2
HV164_RS00490	COG2861	carbohydrate metabolic process
HV164_RS00495	COG4942	peptidase
HV164_RS00505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV164_RS00510	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV164_RS00525	COG1045	serine acetyltransferase
HV164_RS00530	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HV164_RS00535	COG2271	Major facilitator Superfamily
HV164_RS00545	COG2186	Transcriptional regulator
HV164_RS00565	COG3722	fumarate hydratase activity
HV164_RS00575	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV164_RS00575	COG2213	PTS system mannitol-specific
HV164_RS00585	COG1566	PFAM secretion protein HlyD family protein
HV164_RS00590	COG0625	glutathione transferase activity
HV164_RS00600	COG3276	selenocysteine insertion sequence binding
HV164_RS00605	COG1454	alcohol dehydrogenase
HV164_RS00610	COG1012	belongs to the aldehyde dehydrogenase family
HV164_RS00620	COG1566	PFAM secretion protein HlyD family protein
HV164_RS00625	COG0583	DNA-binding transcription factor activity
HV164_RS00630	COG3713	MltA-interacting MipA family protein
HV164_RS00640	COG2211	Major facilitator Superfamily
HV164_RS00650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV164_RS00655	COG3977	Valine--pyruvate aminotransferase
HV164_RS00660	COG0366	Alpha amylase catalytic
HV164_RS00665	COG2992	FlgJ-related protein
HV164_RS00670	COG2207	Transcriptional regulator
HV164_RS00670	COG1609	Transcriptional regulator
HV164_RS00680	COG1070	Carbohydrate kinase
HV164_RS00685	COG4682	membrane
HV164_RS00690	COG3274	enterobacterial common antigen metabolic process
HV164_RS00715	COG1278	Cold shock
HV164_RS00720	COG2944	sequence-specific DNA binding
HV164_RS00735	COG2271	Major facilitator Superfamily
HV164_RS00740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV164_RS00750	COG1609	Transcriptional regulator
HV164_RS00755	COG2885	chlorophyll binding
HV164_RS00760	COG0243	molybdopterin cofactor binding
HV164_RS00765	COG0456	acetyltransferase
HV164_RS00770	COG2818	Glycosylase
HV164_RS00775	COG5571	outer membrane autotransporter
HV164_RS00780	COG2223	nitrite transmembrane transporter activity
HV164_RS00805	COG0747	negative chemotaxis
HV164_RS00810	COG0601	transmembrane transport
HV164_RS00815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV164_RS00820	COG0444	Belongs to the ABC transporter superfamily
HV164_RS00825	COG4608	Belongs to the ABC transporter superfamily
HV164_RS00830	COG2204	response regulator
HV164_RS00835	COG0814	amino acid
HV164_RS00840	COG0626	cystathionine gamma-synthase activity
HV164_RS00845	COG2200	EAL domain
HV164_RS00845	COG2199	diguanylate cyclase activity
HV164_RS00860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV164_RS00865	COG2200	EAL domain
HV164_RS00870	COG2982	Protein involved in outer membrane biogenesis
HV164_RS00875	COG0477	Major facilitator Superfamily
HV164_RS00880	COG1295	ribonuclease BN
HV164_RS00885	COG0583	DNA-binding transcription factor activity
HV164_RS00895	COG2197	response regulator
HV164_RS00920	COG1858	cytochrome C peroxidase
HV164_RS00925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV164_RS00930	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HV164_RS00935	COG0339	signal peptide processing
HV164_RS00960	COG0589	response to stress
HV164_RS00970	COG0306	phosphate transporter
HV164_RS00975	COG2081	HI0933 family
HV164_RS00990	COG3479	Phenolic acid decarboxylase
HV164_RS00995	COG2091	lysine biosynthetic process via aminoadipic acid
HV164_RS01000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV164_RS01005	COG1028	Short-chain dehydrogenase reductase Sdr
HV164_RS01015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV164_RS01040	COG1216	Glycosyl transferase, family 2
HV164_RS01060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HV164_RS01090	COG0628	permease
HV164_RS01105	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HV164_RS01120	COG3714	YhhN family
HV164_RS01130	COG3776	membrane
HV164_RS01135	COG0742	ribosomal rna small subunit methyltransferase
HV164_RS01140	COG0552	protein localization to endoplasmic reticulum
HV164_RS01145	COG2884	Cell division ATP-binding protein ftsE
HV164_RS01150	COG2177	Part of the ABC transporter FtsEX involved in
HV164_RS01170	COG0683	leucine binding
HV164_RS01180	COG4177	L-phenylalanine transmembrane transporter activity
HV164_RS01185	COG0411	ABC transporter
HV164_RS01210	COG1175	transmembrane transport
HV164_RS01225	COG0584	glycerophosphoryl diester phosphodiesterase
HV164_RS01235	COG0405	Gamma-glutamyltransferase
HV164_RS01245	COG1247	-acetyltransferase
HV164_RS01250	COG0673	inositol 2-dehydrogenase activity
HV164_RS01255	COG1741	Belongs to the pirin family
HV164_RS01260	COG1609	Transcriptional regulator
HV164_RS01265	COG3265	gluconokinase activity
HV164_RS01270	COG2610	gluconate transmembrane transporter activity
HV164_RS01285	COG2095	MarC family integral membrane protein
HV164_RS01290	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV164_RS01315	COG0058	SHG alpha-glucan phosphorylase activity
HV164_RS01320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV164_RS01335	COG1349	DNA-binding transcription factor activity
HV164_RS01345	COG0058	SHG alpha-glucan phosphorylase activity
HV164_RS01350	COG1640	4-alpha-glucanotransferase
HV164_RS01355	COG2610	gluconate transmembrane transporter activity
HV164_RS01385	COG1918	ferrous iron import across plasma membrane
HV164_RS01390	COG2183	response to ionizing radiation
HV164_RS01395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV164_RS01400	COG0745	RESPONSE REGULATOR receiver
HV164_RS01415	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HV164_RS01425	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HV164_RS01430	COG1011	Hydrolase
HV164_RS01440	COG0494	nUDIX hydrolase
HV164_RS01445	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HV164_RS01450	COG4972	Pilus assembly protein
HV164_RS01485	COG3266	domain, Protein
HV164_RS01490	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV164_RS01495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV164_RS01505	COG0180	Tryptophanyl-tRNA synthetase
HV164_RS01525	COG2146	nitrite reductase [NAD(P)H] activity
HV164_RS01530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV164_RS01555	COG0512	Glutamine amidotransferase of anthranilate synthase
HV164_RS01560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HV164_RS01565	COG1289	transmembrane transporter activity
HV164_RS01575	COG1765	OsmC-like protein
HV164_RS01580	COG3954	Phosphoribulokinase
HV164_RS01590	COG0429	hydrolase of the alpha beta-hydrolase fold
HV164_RS01600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HV164_RS01635	COG0679	Auxin Efflux Carrier
HV164_RS01645	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HV164_RS01655	COG0488	(ABC) transporter
HV164_RS01670	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HV164_RS01675	COG1047	Peptidyl-prolyl cis-trans
HV164_RS01685	COG0545	Peptidyl-prolyl cis-trans isomerase
HV164_RS01690	COG2964	Protein conserved in bacteria
HV164_RS01720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HV164_RS01725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HV164_RS01745	COG0051	transcription antitermination factor activity, RNA binding
HV164_RS01755	COG0088	Forms part of the polypeptide exit tunnel
HV164_RS01770	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HV164_RS01845	COG0200	Binds to the 23S rRNA
HV164_RS01850	COG0201	protein transport
HV164_RS01865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HV164_RS01880	COG0203	ribosomal protein L17
HV164_RS01890	COG0789	Transcriptional regulator
HV164_RS01895	COG3036	rescue of stalled ribosome
HV164_RS01925	COG0758	DNA mediated transformation
HV164_RS01935	COG0551	DNA topoisomerase type I activity
HV164_RS01955	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV164_RS01995	COG1126	abc transporter atp-binding protein
HV164_RS02000	COG0765	amino acid transport
HV164_RS02005	COG4597	amino acid ABC transporter
HV164_RS02010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV164_RS02020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV164_RS02025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV164_RS02030	COG1309	transcriptional regulator
HV164_RS02040	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HV164_RS02070	COG4145	pantothenate transmembrane transporter activity
HV164_RS02075	COG3924	membrane
HV164_RS02080	COG0439	Biotin carboxylase
HV164_RS02085	COG0511	ligase activity, forming carbon-carbon bonds
HV164_RS02100	COG0604	alcohol dehydrogenase
HV164_RS02105	COG2199	diguanylate cyclase activity
HV164_RS02105	COG2200	EAL domain
HV164_RS02115	COG1077	Cell shape determining protein MreB Mrl
HV164_RS02120	COG1792	Involved in formation and maintenance of cell shape
HV164_RS02125	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HV164_RS02135	COG1530	ribonuclease E activity
HV164_RS02140	COG3164	Protein of unknown function
HV164_RS02145	COG0312	modulator of DNA gyrase
HV164_RS02150	COG0583	DNA-binding transcription factor activity
HV164_RS02170	COG2732	(Barnase) inhibitor
HV164_RS02190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV164_RS02195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV164_RS02200	COG3105	Protein conserved in bacteria
HV164_RS02205	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HV164_RS02215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HV164_RS02220	COG0625	glutathione transferase activity
HV164_RS02225	COG2969	positive regulation of protein catabolic process
HV164_RS02230	COG3069	C4-dicarboxylate transmembrane transporter activity
HV164_RS02235	COG2186	Transcriptional regulator
HV164_RS02255	COG2731	YhcH YjgK YiaL family protein
HV164_RS02260	COG0402	S-adenosylhomocysteine deaminase activity
HV164_RS02265	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HV164_RS02275	COG4804	nuclease activity
HV164_RS02280	COG0493	'glutamate synthase
HV164_RS02285	COG0070	glutamate synthase
HV164_RS02285	COG0069	glutamate synthase activity
HV164_RS02285	COG0067	glutamate synthase
HV164_RS02290	COG1242	4 iron, 4 sulfur cluster binding
HV164_RS02295	COG5002	protein histidine kinase activity
HV164_RS02295	COG2198	Histidine kinase
HV164_RS02295	COG0784	Response regulator, receiver
HV164_RS02300	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HV164_RS02310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV164_RS02325	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV164_RS02335	COG1137	ATPase activity
HV164_RS02340	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HV164_RS02345	COG3117	lipopolysaccharide transmembrane transporter activity
HV164_RS02350	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HV164_RS02360	COG0530	calcium, potassium:sodium antiporter activity
HV164_RS02365	COG1127	ABC transporter
HV164_RS02370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HV164_RS02375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV164_RS02380	COG2854	intermembrane phospholipid transfer
HV164_RS02385	COG3113	response to antibiotic
HV164_RS02390	COG5007	Belongs to the BolA IbaG family
HV164_RS02420	COG3423	Transcriptional regulator
HV164_RS02425	COG0142	geranyltranstransferase activity
HV164_RS02430	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HV164_RS02435	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HV164_RS02440	COG0697	spore germination
HV164_RS02445	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HV164_RS02450	COG2027	D-alanyl-D-alanine carboxypeptidase
HV164_RS02460	COG1534	Rna-binding protein
HV164_RS02470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HV164_RS02475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HV164_RS02485	COG3069	C4-dicarboxylate transmembrane transporter activity
HV164_RS02490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV164_RS02495	COG0583	DNA-binding transcription factor activity
HV164_RS02500	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HV164_RS02525	COG0195	Participates in both transcription termination and antitermination
HV164_RS02530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HV164_RS02535	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HV164_RS02565	COG0513	Belongs to the DEAD box helicase family
HV164_RS02570	COG0814	amino acid
HV164_RS02575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV164_RS02580	COG0826	peptidase U32
HV164_RS02585	COG0826	peptidase U32
HV164_RS02590	COG3154	lipid carrier protein
HV164_RS02595	COG3153	acetyltransferase
HV164_RS02610	COG0702	epimerase
HV164_RS02615	COG2823	Periplasmic or secreted lipoprotein
HV164_RS02635	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HV164_RS02645	COG2222	sugar isomerase
HV164_RS02650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV164_RS02655	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV164_RS02660	COG3716	PTS system mannose fructose sorbose family IID component
HV164_RS02670	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV164_RS02680	COG1349	DNA-binding transcription factor activity
HV164_RS02685	COG1349	DNA-binding transcription factor activity
HV164_RS02690	COG1940	carbohydrate kinase activity
HV164_RS02695	COG0673	inositol 2-dehydrogenase activity
HV164_RS02700	COG3842	ATPase activity
HV164_RS02705	COG0395	ABC-type sugar transport system, permease component
HV164_RS02710	COG1175	transmembrane transport
HV164_RS02720	COG2721	sulfolactate sulfo-lyase activity
HV164_RS02725	COG2271	Major facilitator Superfamily
HV164_RS02735	COG2084	Dehydrogenase
HV164_RS02740	COG1929	Belongs to the glycerate kinase type-1 family
HV164_RS02750	COG0583	DNA-binding transcription factor activity
HV164_RS02770	COG1882	Formate acetyltransferase
HV164_RS02775	COG0251	oxidation-reduction process
HV164_RS02780	COG1760	l-serine dehydratase
HV164_RS02785	COG0814	amino acid
HV164_RS02800	COG1741	Belongs to the pirin family
HV164_RS02805	COG0583	DNA-binding transcription factor activity
HV164_RS02810	COG3152	Membrane
HV164_RS02815	COG0435	Glutathione S-transferase
HV164_RS02820	COG2259	Doxx family
HV164_RS02830	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HV164_RS02835	COG4575	ribosome binding
HV164_RS02840	COG1422	Protein of unknown function (DUF1090)
HV164_RS02850	COG0586	Pfam SNARE associated Golgi protein
HV164_RS02855	COG2186	Transcriptional regulator
HV164_RS02860	COG2271	Major facilitator Superfamily
HV164_RS02870	COG2721	sulfolactate sulfo-lyase activity
HV164_RS02890	COG0673	inositol 2-dehydrogenase activity
HV164_RS02895	COG1451	nucleotide metabolic process
HV164_RS02905	COG0446	pyridine nucleotide-disulphide oxidoreductase
HV164_RS02905	COG1902	pentaerythritol trinitrate reductase activity
HV164_RS02910	COG3408	Glycogen debranching enzyme
HV164_RS02910	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HV164_RS02920	COG0531	amino acid
HV164_RS02925	COG2731	YhcH YjgK YiaL family protein
HV164_RS02930	COG3250	beta-galactosidase activity
HV164_RS02935	COG1609	Transcriptional regulator
HV164_RS02940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HV164_RS02950	COG0840	transmembrane signaling receptor activity
HV164_RS02955	COG1695	Transcriptional regulator
HV164_RS02960	COG2375	cellular response to nickel ion
HV164_RS02970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV164_RS03035	COG0583	DNA-binding transcription factor activity
HV164_RS03065	COG0358	DNA primase activity
HV164_RS03070	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HV164_RS03075	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HV164_RS03080	COG0471	metal ion transport
HV164_RS03085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV164_RS03105	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV164_RS03120	COG4991	sh3 domain protein
HV164_RS03125	COG3025	triphosphatase activity
HV164_RS03140	COG2268	Band 7 protein
HV164_RS03170	COG3384	dioxygenase
HV164_RS03175	COG0754	glutathionylspermidine amidase activity
HV164_RS03185	COG1538	Outer membrane efflux protein
HV164_RS03190	COG0494	nUDIX hydrolase
HV164_RS03195	COG3151	Protein conserved in bacteria
HV164_RS03200	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HV164_RS03205	COG3150	esterase
HV164_RS03210	COG0187	DNA topoisomerase II activity
HV164_RS03225	COG2211	Major facilitator Superfamily
HV164_RS03230	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HV164_RS03235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HV164_RS03240	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV164_RS03255	COG3111	PFAM Bacterial OB fold (BOF) protein
HV164_RS03275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HV164_RS03280	COG1032	radical SAM domain protein
HV164_RS03285	COG0471	metal ion transport
HV164_RS03290	COG0656	L-ascorbic acid biosynthetic process
HV164_RS03295	COG1979	alcohol dehydrogenase
HV164_RS03300	COG2207	Transcriptional regulator
HV164_RS03305	COG0586	Pfam SNARE associated Golgi protein
HV164_RS03310	COG0626	cystathionine gamma-synthase activity
HV164_RS03320	COG0848	biopolymer transport protein
HV164_RS03345	COG0667	Aldo Keto reductase
HV164_RS03350	COG0840	transmembrane signaling receptor activity
HV164_RS03360	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HV164_RS03365	COG0437	4 iron, 4 sulfur cluster binding
HV164_RS03370	COG5557	Pfam Polysulphide reductase, NrfD
HV164_RS03375	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HV164_RS03380	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HV164_RS03385	COG1773	rubredoxin
HV164_RS03395	COG0298	carbon dioxide binding
HV164_RS03400	COG0625	glutathione transferase activity
HV164_RS03405	COG0243	molybdopterin cofactor binding
HV164_RS03410	COG0754	glutathionylspermidine amidase activity
HV164_RS03435	COG1811	Na channel or pump
HV164_RS03440	COG1982	Orn Lys Arg decarboxylase major
HV164_RS03445	COG2211	Major facilitator Superfamily
HV164_RS03460	COG1194	a g-specific adenine glycosylase
HV164_RS03470	COG3171	Protein conserved in bacteria
HV164_RS03480	COG0252	asparaginase activity
HV164_RS03485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV164_RS03500	COG0762	integral membrane protein
HV164_RS03505	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HV164_RS03510	COG2805	Type II/IV secretion system protein
HV164_RS03525	COG0189	ligase activity
HV164_RS03530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HV164_RS03535	COG2356	endonuclease I
HV164_RS03540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV164_RS03550	COG2814	Major facilitator Superfamily
HV164_RS03575	COG1166	arginine decarboxylase activity
HV164_RS03585	COG0501	Belongs to the peptidase M48B family
HV164_RS03590	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV164_RS03595	COG1122	ATPase activity
HV164_RS03600	COG1122	ATPase activity
HV164_RS03630	COG0191	fructose-bisphosphate aldolase activity
HV164_RS03640	COG0668	transmembrane transport
HV164_RS03645	COG1279	arginine transmembrane transporter activity
HV164_RS03650	COG2968	Membrane
HV164_RS03655	COG0583	DNA-binding transcription factor activity
HV164_RS03660	COG0427	acetyl-CoA hydrolase
HV164_RS03665	COG1024	Enoyl-CoA hydratase
HV164_RS03670	COG1703	isobutyryl-CoA mutase activity
HV164_RS03675	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV164_RS03675	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV164_RS03690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV164_RS03695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HV164_RS03715	COG0006	proline dipeptidase activity
HV164_RS03720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV164_RS03725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV164_RS03750	COG2723	6-phospho-beta-galactosidase activity
HV164_RS03755	COG1737	Transcriptional regulator
HV164_RS03765	COG1272	protein, Hemolysin III
HV164_RS03775	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HV164_RS03800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HV164_RS03820	COG4942	peptidase
HV164_RS03840	COG1470	cell adhesion involved in biofilm formation
HV164_RS03840	COG1388	LysM domain
HV164_RS03845	COG0457	Tetratricopeptide repeat
HV164_RS03850	COG0726	polysaccharide deacetylase
HV164_RS03850	COG1649	PFAM Uncharacterised BCR, COG1649
HV164_RS03855	COG1215	transferase activity, transferring glycosyl groups
HV164_RS03865	COG3592	Divergent 4Fe-4S mono-cluster
HV164_RS03870	COG2388	GCN5-related N-acetyl-transferase
HV164_RS03875	COG0583	DNA-binding transcription factor activity
HV164_RS03880	COG0666	response to abiotic stimulus
HV164_RS03890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV164_RS03895	COG1304	FMN binding
HV164_RS03905	COG0549	Belongs to the carbamate kinase family
HV164_RS03910	COG0402	S-adenosylhomocysteine deaminase activity
HV164_RS03925	COG0814	amino acid
HV164_RS03940	COG0183	Belongs to the thiolase family
HV164_RS03945	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HV164_RS03950	COG0823	Involved in the tonB-independent uptake of proteins
HV164_RS03960	COG1028	Short-chain dehydrogenase reductase Sdr
HV164_RS03965	COG2814	Major facilitator Superfamily
HV164_RS03975	COG3842	ATPase activity
HV164_RS03980	COG0395	ABC-type sugar transport system, permease component
HV164_RS03985	COG1175	transmembrane transport
HV164_RS03995	COG1794	racemase activity, acting on amino acids and derivatives
HV164_RS04015	COG3188	usher protein
HV164_RS04020	COG3121	Chaperone
HV164_RS04025	COG0583	DNA-binding transcription factor activity
HV164_RS04035	COG1609	Transcriptional regulator
HV164_RS04040	COG1609	Transcriptional regulator
HV164_RS04055	COG0667	Aldo Keto reductase
HV164_RS04065	COG0861	Integral membrane protein TerC family
HV164_RS04095	COG2165	general secretion pathway protein
HV164_RS04100	COG4795	General secretion pathway protein
HV164_RS04110	COG4967	type IV pilus modification protein PilV
HV164_RS04115	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HV164_RS04125	COG1074	ATP-dependent DNA helicase activity
HV164_RS04130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HV164_RS04135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HV164_RS04135	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HV164_RS04140	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV164_RS04160	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HV164_RS04165	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HV164_RS04170	COG2166	iron-sulfur cluster assembly
HV164_RS04175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HV164_RS04185	COG0583	DNA-binding transcription factor activity
HV164_RS04190	COG2363	Small membrane protein
HV164_RS04200	COG1349	DNA-binding transcription factor activity
HV164_RS04210	COG1070	Carbohydrate kinase
HV164_RS04220	COG1129	ABC transporter
HV164_RS04225	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV164_RS04235	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HV164_RS04245	COG0235	Class ii aldolase
HV164_RS04250	COG1454	alcohol dehydrogenase
HV164_RS04260	COG1760	l-serine dehydratase
HV164_RS04265	COG0814	amino acid
HV164_RS04270	COG1611	Belongs to the LOG family
HV164_RS04285	COG3098	single-species biofilm formation
HV164_RS04290	COG0564	pseudouridine synthase activity
HV164_RS04295	COG0716	FMN binding
HV164_RS04310	COG2271	Major facilitator Superfamily
HV164_RS04315	COG4948	Mandelate Racemase Muconate Lactonizing
HV164_RS04320	COG4948	Mandelate Racemase Muconate Lactonizing
HV164_RS04325	COG1929	Belongs to the glycerate kinase type-1 family
HV164_RS04330	COG2205	protein histidine kinase activity
HV164_RS04330	COG4999	Histidine kinase
HV164_RS04330	COG3437	response regulator, receiver
HV164_RS04330	COG3850	Histidine kinase
HV164_RS04340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV164_RS04345	COG3956	TIGRFAM MazG family protein
HV164_RS04360	COG1737	Transcriptional regulator
HV164_RS04365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV164_RS04365	COG1263	PTS System
HV164_RS04365	COG2190	(PTS) system
HV164_RS04370	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HV164_RS04375	COG0602	queuosine metabolic process
HV164_RS04380	COG0720	synthase
HV164_RS04385	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HV164_RS04400	COG2234	aminopeptidase activity
HV164_RS04435	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HV164_RS04455	COG4942	peptidase
HV164_RS04455	COG1388	LysM domain
HV164_RS04470	COG0163	prenyltransferase activity
HV164_RS04475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV164_RS04550	COG5001	Diguanylate cyclase
HV164_RS04550	COG3300	MHYT domain
HV164_RS04555	COG2200	EAL domain
HV164_RS04565	COG2201	protein-glutamate methylesterase activity
HV164_RS04570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HV164_RS04580	COG0745	RESPONSE REGULATOR receiver
HV164_RS04610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV164_RS04615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV164_RS04620	COG1121	(ABC) transporter
HV164_RS04640	COG0309	Hydrogenase expression formation protein (HypE)
HV164_RS04645	COG0409	Hydrogenase expression formation protein
HV164_RS04650	COG0298	carbon dioxide binding
HV164_RS04655	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HV164_RS04670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV164_RS04675	COG0651	ATP synthesis coupled electron transport
HV164_RS04680	COG0650	Formate hydrogenlyase subunit 4
HV164_RS04685	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HV164_RS04685	COG3261	NADH dehydrogenase
HV164_RS04690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV164_RS04695	COG3260	NADH ubiquinone oxidoreductase 20
HV164_RS04705	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HV164_RS04715	COG2723	6-phospho-beta-galactosidase activity
HV164_RS04720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV164_RS04720	COG1263	PTS System
HV164_RS04725	COG1609	Transcriptional regulator
HV164_RS04730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV164_RS04735	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HV164_RS04755	COG0517	IMP dehydrogenase activity
HV164_RS04755	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HV164_RS04760	COG1349	DNA-binding transcription factor activity
HV164_RS04765	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV164_RS04770	COG1028	Short-chain dehydrogenase reductase Sdr
HV164_RS04780	COG3732	PTS system glucitol sorbitol-specific
HV164_RS04785	COG3730	PTS system glucitol sorbitol-specific
HV164_RS04790	COG2951	lytic endotransglycosylase activity
HV164_RS04795	COG1546	Belongs to the CinA family
HV164_RS04815	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HV164_RS04845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV164_RS04850	COG1238	metal cluster binding
HV164_RS04865	COG2211	Major facilitator Superfamily
HV164_RS04880	COG2814	Major facilitator Superfamily
HV164_RS04885	COG1566	PFAM secretion protein HlyD family protein
HV164_RS04890	COG1846	Transcriptional regulator
HV164_RS04900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HV164_RS04905	COG2814	Major facilitator Superfamily
HV164_RS04915	COG4176	ABC-type proline glycine betaine transport system permease component
HV164_RS04925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV164_RS04930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV164_RS04945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV164_RS04975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV164_RS04980	COG0640	Transcriptional regulator
HV164_RS04985	COG0401	homolog of Blt101
HV164_RS04990	COG1802	Transcriptional regulator
HV164_RS04995	COG1113	amino acid transport
HV164_RS05000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV164_RS05005	COG1012	belongs to the aldehyde dehydrogenase family
HV164_RS05010	COG0579	oxidoreductase
HV164_RS05025	COG0583	DNA-binding transcription factor activity
HV164_RS05050	COG0642	Histidine kinase
HV164_RS05090	COG0297	glycogen (starch) synthase activity
HV164_RS05095	COG0438	transferase activity, transferring glycosyl groups
HV164_RS05095	COG0297	glycogen (starch) synthase activity
HV164_RS05125	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HV164_RS05130	COG1757	Na H antiporter
HV164_RS05135	COG2169	Transcriptional regulator
HV164_RS05155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV164_RS05160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV164_RS05165	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HV164_RS05170	COG2271	Major facilitator Superfamily
HV164_RS05175	COG0477	Major facilitator Superfamily
HV164_RS05180	COG0363	glucosamine-6-phosphate deaminase activity
HV164_RS05185	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV164_RS05190	COG1940	carbohydrate kinase activity
HV164_RS05190	COG1846	Transcriptional regulator
HV164_RS05215	COG3962	Belongs to the TPP enzyme family
HV164_RS05220	COG0673	inositol 2-dehydrogenase activity
HV164_RS05235	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV164_RS05240	COG0673	inositol 2-dehydrogenase activity
HV164_RS05245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV164_RS05255	COG3718	enzyme involved in inositol metabolism
HV164_RS05270	COG2003	Belongs to the UPF0758 family
HV164_RS05300	COG4983	Phage plasmid primase, P4 family domain protein
HV164_RS05305	COG3311	Transcriptional regulator
HV164_RS05325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HV164_RS05325	COG0784	Response regulator, receiver
HV164_RS05330	COG0582	viral genome integration into host DNA
HV164_RS05340	COG0582	viral genome integration into host DNA
HV164_RS05370	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HV164_RS05375	COG5532	Uncharacterized conserved protein (DUF2303)
HV164_RS05405	COG4626	Terminase
HV164_RS05405	COG1802	Transcriptional regulator
HV164_RS05410	COG4725	Belongs to the MT-A70-like family
HV164_RS05425	COG3646	Phage regulatory protein
HV164_RS05425	COG3645	SOS response
HV164_RS05430	COG1403	HNH endonuclease
HV164_RS05455	COG3179	chitinase
HV164_RS05495	COG4626	Terminase
HV164_RS05495	COG1802	Transcriptional regulator
HV164_RS05500	COG4695	Portal protein
HV164_RS05505	COG0740	serine-type endopeptidase activity
HV164_RS05615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV164_RS05640	COG2867	negative regulation of translational initiation
HV164_RS05650	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV164_RS05655	COG0497	DNA recombination
HV164_RS05670	COG4536	flavin adenine dinucleotide binding
HV164_RS05675	COG4137	Cytochrome C assembly protein
HV164_RS05680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HV164_RS05715	COG2885	chlorophyll binding
HV164_RS05720	COG2199	diguanylate cyclase activity
HV164_RS05735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV164_RS05740	COG1605	Chorismate mutase
HV164_RS05740	COG0287	Prephenate dehydrogenase
HV164_RS05745	COG1605	Chorismate mutase
HV164_RS05745	COG0077	Prephenate dehydratase
HV164_RS05755	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV164_RS05760	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV164_RS05775	COG0542	response to heat
HV164_RS05800	COG0477	Major facilitator Superfamily
HV164_RS05805	COG5544	Lipoprotein
HV164_RS05810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV164_RS05825	COG3118	belongs to the thioredoxin family
HV164_RS05830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV164_RS05845	COG0513	Belongs to the DEAD box helicase family
HV164_RS05855	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HV164_RS05865	COG1595	DNA-templated transcription, initiation
HV164_RS05875	COG3026	antisigma factor binding
HV164_RS05880	COG3086	response to oxidative stress
HV164_RS05890	COG0681	Belongs to the peptidase S26 family
HV164_RS05910	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HV164_RS05920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV164_RS05925	COG1737	Transcriptional regulator
HV164_RS05930	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HV164_RS05935	COG1263	PTS System
HV164_RS05935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV164_RS05940	COG0560	Phosphoserine phosphatase
HV164_RS05960	COG2205	protein histidine kinase activity
HV164_RS05965	COG3170	Tfp pilus assembly protein FimV
HV164_RS05970	COG2204	response regulator
HV164_RS05975	COG0347	Belongs to the P(II) protein family
HV164_RS05980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV164_RS05980	COG1017	nitric oxide dioxygenase activity
HV164_RS06010	COG4638	Rieske (2fe-2S)
HV164_RS06015	COG0583	DNA-binding transcription factor activity
HV164_RS06020	COG1940	carbohydrate kinase activity
HV164_RS06025	COG0457	Tetratricopeptide repeat
HV164_RS06030	COG2814	Major facilitator Superfamily
HV164_RS06030	COG0477	Major facilitator Superfamily
HV164_RS06040	COG2814	Major facilitator Superfamily
HV164_RS06045	COG3711	transcriptional antiterminator
HV164_RS06050	COG0517	IMP dehydrogenase activity
HV164_RS06050	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HV164_RS06055	COG1069	ribulokinase activity
HV164_RS06065	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV164_RS06070	COG1129	ABC transporter
HV164_RS06080	COG3683	transport system, periplasmic component
HV164_RS06085	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HV164_RS06105	COG1104	cysteine desulfurase activity
HV164_RS06110	COG0822	iron-sulfur transferase activity
HV164_RS06130	COG0633	Ferredoxin
HV164_RS06135	COG2975	iron-sulfur cluster assembly
HV164_RS06150	COG2897	thiosulfate sulfurtransferase activity
HV164_RS06155	COG2373	Large extracellular alpha-helical protein
HV164_RS06160	COG4953	penicillin-binding protein 1C
HV164_RS06165	COG0105	UTP biosynthetic process
HV164_RS06170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HV164_RS06190	COG2976	Protein conserved in bacteria
HV164_RS06205	COG3104	oligopeptide transport
HV164_RS06210	COG1645	bacterial-type flagellum-dependent swarming motility
HV164_RS06215	COG1388	LysM domain
HV164_RS06215	COG1470	cell adhesion involved in biofilm formation
HV164_RS06235	COG0516	GMP reductase activity
HV164_RS06235	COG0517	IMP dehydrogenase activity
HV164_RS06245	COG0582	viral genome integration into host DNA
HV164_RS06285	COG3846	protein secretion by the type IV secretion system
HV164_RS06290	COG3093	addiction module antidote protein HigA
HV164_RS06335	COG0668	transmembrane transport
HV164_RS06345	COG2200	EAL domain
HV164_RS06360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HV164_RS06375	COG2723	6-phospho-beta-galactosidase activity
HV164_RS06385	COG2233	PERMEase
HV164_RS06395	COG1393	Belongs to the ArsC family
HV164_RS06400	COG4783	chaperone-mediated protein folding
HV164_RS06405	COG0628	permease
HV164_RS06410	COG3366	ferrous iron transmembrane transporter activity
HV164_RS06415	COG0700	Nucleoside recognition
HV164_RS06420	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV164_RS06425	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HV164_RS06430	COG2716	regulation of RNA biosynthetic process
HV164_RS06440	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HV164_RS06450	COG2321	neutral zinc metallopeptidase
HV164_RS06460	COG0400	carboxylic ester hydrolase activity
HV164_RS06475	COG1393	Belongs to the ArsC family
HV164_RS06485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV164_RS06490	COG3850	Histidine kinase
HV164_RS06495	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV164_RS06495	COG0493	'glutamate synthase
HV164_RS06505	COG5342	invasion associated locus B
HV164_RS06510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV164_RS06535	COG4812	Cobalamin adenosyltransferase
HV164_RS06540	COG0280	phosphate acetyltransferase
HV164_RS06575	COG4819	ethanolamine utilization protein
HV164_RS06595	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HV164_RS06600	COG2207	Transcriptional regulator
HV164_RS06610	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV164_RS06630	COG2837	iron assimilation
HV164_RS06640	COG4150	thiosulfate binding
HV164_RS06645	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HV164_RS06650	COG4208	sulfate ABC transporter
HV164_RS06655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HV164_RS06720	COG3530	Putative quorum-sensing-regulated virulence factor
HV164_RS06725	COG0385	Bile acid
HV164_RS06730	COG0583	DNA-binding transcription factor activity
HV164_RS06735	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HV164_RS06740	COG2211	Major facilitator Superfamily
HV164_RS06745	COG0583	DNA-binding transcription factor activity
HV164_RS06775	COG3415	Transposase
HV164_RS06780	COG3415	Transposase
HV164_RS06795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV164_RS06810	COG0667	Aldo Keto reductase
HV164_RS06815	COG3961	Belongs to the TPP enzyme family
HV164_RS06835	COG3279	Response regulator of the LytR AlgR family
HV164_RS06840	COG3275	phosphorelay sensor kinase activity
HV164_RS06845	COG0436	Aminotransferase
HV164_RS06860	COG1560	Kdo2-lipid A biosynthetic process
HV164_RS06890	COG3122	Protein conserved in bacteria
HV164_RS06910	COG0732	type I restriction modification DNA specificity domain
HV164_RS06945	COG0582	viral genome integration into host DNA
HV164_RS06955	COG2116	formate transmembrane transporter activity
HV164_RS06965	COG2067	long-chain fatty acid transport protein
HV164_RS06970	COG3691	Protein conserved in bacteria
HV164_RS06985	COG2062	phosphohistidine phosphatase, SixA
HV164_RS07010	COG0730	response to heat
HV164_RS07015	COG3101	peptidyl-lysine hydroxylation
HV164_RS07030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV164_RS07050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV164_RS07060	COG0586	Pfam SNARE associated Golgi protein
HV164_RS07070	COG0285	dihydrofolate synthase activity
HV164_RS07075	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HV164_RS07085	COG1286	toxin biosynthetic process
HV164_RS07090	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HV164_RS07100	COG2211	Major facilitator Superfamily
HV164_RS07105	COG1609	Transcriptional regulator
HV164_RS07110	COG0163	prenyltransferase activity
HV164_RS07120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV164_RS07135	COG4598	ABC transporter
HV164_RS07140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV164_RS07145	COG1090	epimerase
HV164_RS07150	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV164_RS07155	COG0625	glutathione transferase activity
HV164_RS07160	COG0625	glutathione transferase activity
HV164_RS07165	COG0622	Phosphoesterase
HV164_RS07175	COG1288	antiporter activity
HV164_RS07200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV164_RS07205	COG0471	metal ion transport
HV164_RS07205	COG0490	domain, Protein
HV164_RS07215	COG0436	Aminotransferase
HV164_RS07220	COG0583	DNA-binding transcription factor activity
HV164_RS07240	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HV164_RS07245	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HV164_RS07265	COG0839	Belongs to the complex I subunit 6 family
HV164_RS07275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HV164_RS07280	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV164_RS07290	COG0784	Response regulator, receiver
HV164_RS07290	COG0835	chemotaxis
HV164_RS07300	COG2153	protein acetylation
HV164_RS07305	COG4575	ribosome binding
HV164_RS07310	COG1169	isochorismate synthase
HV164_RS07390	COG0247	lactate metabolic process
HV164_RS07400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV164_RS07405	COG2271	Major facilitator Superfamily
HV164_RS07410	COG0584	glycerophosphoryl diester phosphodiesterase
HV164_RS07415	COG0583	DNA-binding transcription factor activity
HV164_RS07425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV164_RS07450	COG0183	Belongs to the thiolase family
HV164_RS07455	COG2031	fatty acid transporter
HV164_RS07460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HV164_RS07465	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HV164_RS07470	COG2204	response regulator
HV164_RS07475	COG3852	Histidine kinase
HV164_RS07485	COG2197	response regulator
HV164_RS07490	COG0642	Histidine kinase
HV164_RS07490	COG2198	Histidine kinase
HV164_RS07495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV164_RS07505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HV164_RS07505	COG2169	Transcriptional regulator
HV164_RS07510	COG3145	DNA-N1-methyladenine dioxygenase activity
HV164_RS07515	COG4615	Cyclic peptide transporter
HV164_RS07520	COG2239	Acts as a magnesium transporter
HV164_RS07525	COG0659	secondary active sulfate transmembrane transporter activity
HV164_RS07540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV164_RS07540	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV164_RS07545	COG3062	negative regulation of establishment of protein localization
HV164_RS07555	COG0437	4 iron, 4 sulfur cluster binding
HV164_RS07560	COG0348	domain, Protein
HV164_RS07565	COG3043	anaerobic respiration
HV164_RS07570	COG3005	denitrification pathway
HV164_RS07575	COG4133	protoheme IX ABC transporter activity
HV164_RS07585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HV164_RS07590	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HV164_RS07600	COG1138	Cytochrome C-type biogenesis protein
HV164_RS07605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HV164_RS07610	COG4235	cytochrome complex assembly
HV164_RS07610	COG3088	subunit of a heme lyase
HV164_RS07615	COG2197	response regulator
HV164_RS07665	COG1061	Type III restriction enzyme res subunit
HV164_RS07670	COG1187	pseudouridine synthase activity
HV164_RS07675	COG2814	Major facilitator Superfamily
HV164_RS07685	COG4172	Belongs to the ABC transporter superfamily
HV164_RS07690	COG4239	(ABC) transporter, permease
HV164_RS07695	COG4174	ABC transporter (Permease)
HV164_RS07700	COG4166	transmembrane transport
HV164_RS07705	COG2200	EAL domain
HV164_RS07710	COG0791	NLP P60 protein
HV164_RS07715	COG0671	phosphoesterase, PA-phosphatase related
HV164_RS07720	COG0523	cobalamin synthesis protein
HV164_RS07725	COG0246	Mannitol dehydrogenase
HV164_RS07730	COG1312	Catalyzes the dehydration of D-mannonate
HV164_RS07735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV164_RS07740	COG3005	denitrification pathway
HV164_RS07750	COG3381	protein complex oligomerization
HV164_RS07770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV164_RS07770	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV164_RS07775	COG1105	Belongs to the carbohydrate kinase PfkB family
HV164_RS07780	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HV164_RS07780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV164_RS07780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV164_RS07790	COG2855	membrane
HV164_RS07795	COG0583	DNA-binding transcription factor activity
HV164_RS07800	COG0833	amino acid
HV164_RS07805	COG4771	TonB-dependent receptor
HV164_RS07820	COG2311	Membrane
HV164_RS07835	COG1129	ABC transporter
HV164_RS07860	COG2949	membrane
HV164_RS07870	COG1346	cytolysis
HV164_RS07880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV164_RS07890	COG2226	methyltransferase
HV164_RS07900	COG0586	Pfam SNARE associated Golgi protein
HV164_RS07910	COG1686	Belongs to the peptidase S11 family
HV164_RS07915	COG0277	FAD linked oxidase domain protein
HV164_RS07920	COG1472	Belongs to the glycosyl hydrolase 3 family
HV164_RS07925	COG1732	Glycine betaine
HV164_RS07930	COG1174	glycine betaine transport
HV164_RS07935	COG1125	glycine betaine transport
HV164_RS07940	COG1174	glycine betaine transport
HV164_RS07950	COG0789	Transcriptional regulator
HV164_RS07955	COG3275	phosphorelay sensor kinase activity
HV164_RS07965	COG4807	Protein conserved in bacteria
HV164_RS07985	COG3539	Fimbrial protein
HV164_RS07990	COG3121	Chaperone
HV164_RS07995	COG3188	usher protein
HV164_RS08005	COG5455	response to cobalt ion
HV164_RS08045	COG0351	phosphomethylpyrimidine kinase
HV164_RS08050	COG2188	Transcriptional regulator
HV164_RS08055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV164_RS08060	COG1397	ADP-ribosylglycohydrolase
HV164_RS08065	COG2211	Major facilitator Superfamily
HV164_RS08070	COG1830	Aldolase
HV164_RS08075	COG4948	Mandelate Racemase Muconate Lactonizing
HV164_RS08080	COG0747	negative chemotaxis
HV164_RS08085	COG0601	transmembrane transport
HV164_RS08095	COG0444	Belongs to the ABC transporter superfamily
HV164_RS08100	COG4608	Belongs to the ABC transporter superfamily
HV164_RS08110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV164_RS08115	COG4160	amino acid transport
HV164_RS08120	COG4215	(ABC) transporter
HV164_RS08125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV164_RS08130	COG1126	abc transporter atp-binding protein
HV164_RS08165	COG3023	N-Acetylmuramoyl-L-alanine amidase
HV164_RS08170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV164_RS08175	COG0702	epimerase
HV164_RS08180	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HV164_RS08185	COG0028	Belongs to the TPP enzyme family
HV164_RS08195	COG4529	Protein conserved in bacteria
HV164_RS08205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HV164_RS08220	COG2814	Major facilitator Superfamily
HV164_RS08225	COG1335	isochorismatase
HV164_RS08230	COG0582	viral genome integration into host DNA
HV164_RS08250	COG3459	Glycosyltransferase 36 associated
HV164_RS08260	COG1278	Cold shock
HV164_RS08290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV164_RS08300	COG2431	L-lysine efflux transmembrane transporter activity
HV164_RS08310	COG3593	DNA synthesis involved in DNA repair
HV164_RS08315	COG2990	Protein conserved in bacteria
HV164_RS08320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV164_RS08330	COG1278	Cold shock
HV164_RS08340	COG0542	response to heat
HV164_RS08360	COG0745	RESPONSE REGULATOR receiver
HV164_RS08365	COG2205	protein histidine kinase activity
HV164_RS08395	COG0443	Heat shock 70 kDa protein
HV164_RS08400	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HV164_RS08405	COG5002	protein histidine kinase activity
HV164_RS08405	COG5001	Diguanylate cyclase
HV164_RS08405	COG3447	MASE1 domain protein
HV164_RS08420	COG2982	Protein involved in outer membrane biogenesis
HV164_RS08425	COG1253	flavin adenine dinucleotide binding
HV164_RS08445	COG0463	Glycosyl transferase, family 2
HV164_RS08450	COG1045	serine acetyltransferase
HV164_RS08455	COG0438	transferase activity, transferring glycosyl groups
HV164_RS08465	COG1216	Glycosyl transferase, family 2
HV164_RS08470	COG0110	maltose O-acetyltransferase activity
HV164_RS08475	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HV164_RS08480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV164_RS08485	COG1051	belongs to the nudix hydrolase family
HV164_RS08490	COG0297	glycogen (starch) synthase activity
HV164_RS08500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HV164_RS08505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HV164_RS08510	COG2244	polysaccharide biosynthetic process
HV164_RS08515	COG2327	Polysaccharide pyruvyl transferase
HV164_RS08545	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HV164_RS08585	COG1215	transferase activity, transferring glycosyl groups
HV164_RS08605	COG0438	transferase activity, transferring glycosyl groups
HV164_RS08610	COG0438	transferase activity, transferring glycosyl groups
HV164_RS08680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HV164_RS08695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV164_RS08700	COG0583	DNA-binding transcription factor activity
HV164_RS08710	COG0531	amino acid
HV164_RS08715	COG2925	Exonuclease
HV164_RS08745	COG1289	transmembrane transporter activity
HV164_RS08780	COG4656	Part of a membrane complex involved in electron transport
HV164_RS08790	COG1012	belongs to the aldehyde dehydrogenase family
HV164_RS08970	COG1376	ErfK ybiS ycfS ynhG family protein
HV164_RS08980	COG1178	ABC-type Fe3 transport system permease component
HV164_RS08985	COG1840	ABC-type Fe3 transport system, periplasmic component
HV164_RS09000	COG0583	DNA-binding transcription factor activity
HV164_RS09010	COG0534	Mate efflux family protein
HV164_RS09040	COG3141	response to X-ray
HV164_RS09050	COG2979	Protein of unknown function (DUF533)
HV164_RS09055	COG1770	oligopeptidase
HV164_RS09060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV164_RS09065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV164_RS09075	COG2372	response to copper ion
HV164_RS09080	COG1276	copper resistance
HV164_RS09110	COG3008	intermembrane lipid transfer
HV164_RS09115	COG2995	paraquat-inducible protein a
HV164_RS09120	COG1956	GAF domain-containing protein
HV164_RS09140	COG2814	Major facilitator Superfamily
HV164_RS09145	COG1414	Transcriptional regulator
HV164_RS09175	COG0768	penicillin binding
HV164_RS09180	COG2226	methyltransferase
HV164_RS09195	COG3716	PTS system mannose fructose sorbose family IID component
HV164_RS09200	COG3715	PTS system
HV164_RS09205	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV164_RS09205	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV164_RS09210	COG1253	flavin adenine dinucleotide binding
HV164_RS09215	COG2200	EAL domain
HV164_RS09220	COG1760	l-serine dehydratase
HV164_RS09240	COG0251	oxidation-reduction process
HV164_RS09245	COG1199	ATP-dependent helicase activity
HV164_RS09250	COG1214	PFAM Peptidase M22, glycoprotease
HV164_RS09255	COG3065	identical protein binding
HV164_RS09260	COG0318	PFAM AMP-dependent synthetase and ligase
HV164_RS09265	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HV164_RS09275	COG2894	cell division
HV164_RS09290	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV164_RS09320	COG2719	SpoVR family
HV164_RS09330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HV164_RS09340	COG1619	proteins homologs of microcin C7 resistance protein MccF
HV164_RS09365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV164_RS09365	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HV164_RS09365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV164_RS09370	COG1461	Dihydroxyacetone kinase
HV164_RS09375	COG2376	Dihydroxyacetone kinase
HV164_RS09380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HV164_RS09415	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HV164_RS09420	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HV164_RS09425	COG0745	RESPONSE REGULATOR receiver
HV164_RS09430	COG5002	protein histidine kinase activity
HV164_RS09435	COG0583	DNA-binding transcription factor activity
HV164_RS09440	COG1902	pentaerythritol trinitrate reductase activity
HV164_RS09445	COG0217	transcriptional regulatory protein
HV164_RS09450	COG0012	GTP binding
HV164_RS09470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HV164_RS09470	COG2857	Cytochrome c1
HV164_RS09485	COG1120	ATPase activity
HV164_RS09490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV164_RS09505	COG0659	secondary active sulfate transmembrane transporter activity
HV164_RS09535	COG2890	protein-(glutamine-N5) methyltransferase activity
HV164_RS09555	COG0387	Pfam Sodium calcium exchanger
HV164_RS09560	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HV164_RS09570	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HV164_RS09575	COG3707	response regulator
HV164_RS09580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV164_RS09585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV164_RS09590	COG1116	anion transmembrane transporter activity
HV164_RS09595	COG2146	nitrite reductase [NAD(P)H] activity
HV164_RS09595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV164_RS09600	COG0243	molybdopterin cofactor binding
HV164_RS09605	COG4932	domain protein
HV164_RS09610	COG2197	response regulator
HV164_RS09615	COG3850	Histidine kinase
HV164_RS09620	COG2223	nitrite transmembrane transporter activity
HV164_RS09625	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV164_RS09630	COG1140	nitrate reductase beta subunit
HV164_RS09635	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV164_RS09640	COG2181	nitrate reductase activity
HV164_RS09670	COG0788	formyltetrahydrofolate deformylase activity
HV164_RS09680	COG1752	Esterase of the alpha-beta hydrolase superfamily
HV164_RS09685	COG0745	RESPONSE REGULATOR receiver
HV164_RS09690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HV164_RS09700	COG1435	thymidine kinase activity
HV164_RS09705	COG1012	belongs to the aldehyde dehydrogenase family
HV164_RS09705	COG1454	alcohol dehydrogenase
HV164_RS09710	COG2095	MarC family integral membrane protein
HV164_RS09730	COG0444	Belongs to the ABC transporter superfamily
HV164_RS09740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV164_RS09765	COG2350	Protein conserved in bacteria
HV164_RS09790	COG3047	cAMP biosynthetic process
HV164_RS09805	COG3706	GGDEF domain
HV164_RS09830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HV164_RS09840	COG0009	L-threonylcarbamoyladenylate synthase
HV164_RS09855	COG1028	Short-chain dehydrogenase reductase Sdr
HV164_RS09860	COG0616	signal peptide processing
HV164_RS09890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HV164_RS09900	COG0671	phosphoesterase, PA-phosphatase related
HV164_RS09905	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HV164_RS09910	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HV164_RS09920	COG0023	Translation Initiation Factor
HV164_RS09930	COG1349	DNA-binding transcription factor activity
HV164_RS09940	COG5001	Diguanylate cyclase
HV164_RS09950	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV164_RS09950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV164_RS09955	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HV164_RS09975	COG4171	peptide transport system, permease
HV164_RS09990	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV164_RS09995	COG1842	Phage shock protein A
HV164_RS10005	COG1983	PspC domain protein
HV164_RS10015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV164_RS10020	COG3106	COG3106 Predicted ATPase
HV164_RS10035	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HV164_RS10040	COG4948	Mandelate Racemase Muconate Lactonizing
HV164_RS10045	COG2866	Carboxypeptidase
HV164_RS10050	COG4166	transmembrane transport
HV164_RS10070	COG1349	DNA-binding transcription factor activity
HV164_RS10075	COG0346	lactoylglutathione lyase activity
HV164_RS10080	COG0668	transmembrane transport
HV164_RS10085	COG3182	Iron-regulated membrane protein
HV164_RS10110	COG2840	Smr protein MutS2
HV164_RS10115	COG3706	GGDEF domain
HV164_RS10125	COG0840	transmembrane signaling receptor activity
HV164_RS10140	COG0513	Belongs to the DEAD box helicase family
HV164_RS10150	COG0582	viral genome integration into host DNA
HV164_RS10155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV164_RS10175	COG2135	peptidase activity
HV164_RS10190	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV164_RS10195	COG0674	pyruvate-flavodoxin oxidoreductase activity
HV164_RS10195	COG1013	pyruvate-flavodoxin oxidoreductase activity
HV164_RS10195	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV164_RS10195	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HV164_RS10200	COG3042	response to heat
HV164_RS10205	COG3187	Heat shock protein
HV164_RS10210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HV164_RS10215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HV164_RS10230	COG2911	Protein conserved in bacteria
HV164_RS10240	COG3784	Protein of unknown function (DUF1318)
HV164_RS10245	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HV164_RS10250	COG4589	Belongs to the CDS family
HV164_RS10260	COG2267	carboxylic ester hydrolase activity
HV164_RS10265	COG2453	phosphatase
HV164_RS10265	COG0671	phosphoesterase, PA-phosphatase related
HV164_RS10285	COG1643	Atp-dependent helicase
HV164_RS10290	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV164_RS10295	COG1012	belongs to the aldehyde dehydrogenase family
HV164_RS10340	COG3038	cytochrome b561
HV164_RS10345	COG0697	spore germination
HV164_RS10350	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HV164_RS10350	COG3264	Mechanosensitive ion channel
HV164_RS10390	COG0840	transmembrane signaling receptor activity
HV164_RS10395	COG0583	DNA-binding transcription factor activity
HV164_RS10400	COG1227	inorganic diphosphatase activity
HV164_RS10405	COG5383	Protein conserved in bacteria
HV164_RS10415	COG2841	Protein conserved in bacteria
HV164_RS10425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV164_RS10430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV164_RS10435	COG1275	C4-dicarboxylate transporter malic acid transport protein
HV164_RS10440	COG0500	methyltransferase
HV164_RS10450	COG0697	spore germination
HV164_RS10460	COG3135	benzoate transporter
HV164_RS10465	COG1396	sequence-specific DNA binding
HV164_RS10470	COG0826	peptidase U32
HV164_RS10485	COG1294	oxidase, subunit
HV164_RS10490	COG1271	oxidase subunit
HV164_RS10495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV164_RS10500	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV164_RS10505	COG3842	ATPase activity
HV164_RS10510	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV164_RS10515	COG1177	transmembrane transport
HV164_RS10550	COG0456	acetyltransferase
HV164_RS10555	COG1396	sequence-specific DNA binding
HV164_RS10585	COG0747	negative chemotaxis
HV164_RS10595	COG3238	Protein conserved in bacteria
HV164_RS10600	COG1247	-acetyltransferase
HV164_RS10610	COG2130	NADP-dependent
HV164_RS10630	COG0840	transmembrane signaling receptor activity
HV164_RS10635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV164_RS10640	COG1473	amidohydrolase
HV164_RS10645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV164_RS10650	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HV164_RS10665	COG1126	abc transporter atp-binding protein
HV164_RS10670	COG2271	Major facilitator Superfamily
HV164_RS10680	COG1609	Transcriptional regulator
HV164_RS10690	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HV164_RS10695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV164_RS10700	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HV164_RS10705	COG0384	phenazine biosynthesis protein PhzF
HV164_RS10710	COG2181	nitrate reductase activity
HV164_RS10715	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV164_RS10720	COG1140	nitrate reductase beta subunit
HV164_RS10725	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV164_RS10765	COG0437	4 iron, 4 sulfur cluster binding
HV164_RS10770	COG2864	formate dehydrogenase
HV164_RS10775	COG3093	addiction module antidote protein HigA
HV164_RS10785	COG0488	(ABC) transporter
HV164_RS10800	COG1764	response to oxidative stress
HV164_RS10805	COG1028	Short-chain dehydrogenase reductase Sdr
HV164_RS10810	COG2610	gluconate transmembrane transporter activity
HV164_RS10815	COG1250	3-hydroxyacyl-CoA dehydrogenase
HV164_RS10825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HV164_RS10830	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HV164_RS10835	COG0583	DNA-binding transcription factor activity
HV164_RS10840	COG4608	Belongs to the ABC transporter superfamily
HV164_RS10845	COG0444	Belongs to the ABC transporter superfamily
HV164_RS10850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV164_RS10855	COG0601	transmembrane transport
HV164_RS10860	COG0747	negative chemotaxis
HV164_RS10865	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HV164_RS10880	COG0840	transmembrane signaling receptor activity
HV164_RS10885	COG1566	PFAM secretion protein HlyD family protein
HV164_RS10905	COG4628	conserved protein (DUF2132)
HV164_RS10930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV164_RS10935	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HV164_RS10950	COG0702	epimerase
HV164_RS10965	COG1064	alcohol dehydrogenase
HV164_RS10980	COG0656	L-ascorbic acid biosynthetic process
HV164_RS11000	COG5002	protein histidine kinase activity
HV164_RS11060	COG3781	membrane
HV164_RS11085	COG1012	belongs to the aldehyde dehydrogenase family
HV164_RS11090	COG0583	DNA-binding transcription factor activity
HV164_RS11105	COG1846	Transcriptional regulator
HV164_RS11110	COG4977	sequence-specific DNA binding
HV164_RS11120	COG0697	spore germination
HV164_RS11125	COG2814	Major facilitator Superfamily
HV164_RS11135	COG3706	GGDEF domain
HV164_RS11145	COG4221	oxidoreductase activity
HV164_RS11150	COG1802	Transcriptional regulator
HV164_RS11160	COG0246	Mannitol dehydrogenase
HV164_RS11170	COG1063	alcohol dehydrogenase
HV164_RS11175	COG4948	Mandelate Racemase Muconate Lactonizing
HV164_RS11190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV164_RS11205	COG0243	molybdopterin cofactor binding
HV164_RS11210	COG0437	4 iron, 4 sulfur cluster binding
HV164_RS11215	COG3302	dmso reductase anchor subunit
HV164_RS11220	COG3381	protein complex oligomerization
HV164_RS11230	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HV164_RS11235	COG1940	carbohydrate kinase activity
HV164_RS11240	COG0583	DNA-binding transcription factor activity
HV164_RS11245	COG2814	Major facilitator Superfamily
HV164_RS11255	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HV164_RS11265	COG3591	Belongs to the peptidase S1B family
HV164_RS11280	COG0628	permease
HV164_RS11285	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HV164_RS11290	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HV164_RS11300	COG0531	amino acid
HV164_RS11310	COG3136	membrane protein required for alginate biosynthesis
HV164_RS11315	COG0745	RESPONSE REGULATOR receiver
HV164_RS11325	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HV164_RS11340	COG2205	protein histidine kinase activity
HV164_RS11355	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV164_RS11355	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV164_RS11360	COG1482	cell wall glycoprotein biosynthetic process
HV164_RS11365	COG5339	Protein conserved in bacteria
HV164_RS11370	COG1609	Transcriptional regulator
HV164_RS11375	COG1263	PTS System
HV164_RS11375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV164_RS11380	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HV164_RS11395	COG0673	inositol 2-dehydrogenase activity
HV164_RS11445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HV164_RS11455	COG0625	glutathione transferase activity
HV164_RS11460	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HV164_RS11475	COG3895	Periplasmic Protein
HV164_RS11500	COG1566	PFAM secretion protein HlyD family protein
HV164_RS11515	COG4989	oxidoreductase activity
HV164_RS11520	COG3313	Fe-S protein
HV164_RS11525	COG1309	transcriptional regulator
HV164_RS11530	COG1902	pentaerythritol trinitrate reductase activity
HV164_RS11535	COG0346	lactoylglutathione lyase activity
HV164_RS11545	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HV164_RS11550	COG0791	NLP P60 protein
HV164_RS11555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HV164_RS11560	COG2814	Major facilitator Superfamily
HV164_RS11575	COG0583	DNA-binding transcription factor activity
HV164_RS11580	COG2814	Major facilitator Superfamily
HV164_RS11585	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV164_RS11590	COG0307	riboflavin synthase, alpha
HV164_RS11600	COG0564	pseudouridine synthase activity
HV164_RS11635	COG1309	transcriptional regulator
HV164_RS11645	COG0628	permease
HV164_RS11650	COG3706	GGDEF domain
HV164_RS11695	COG1470	cell adhesion involved in biofilm formation
HV164_RS11695	COG1388	LysM domain
HV164_RS11700	COG0583	DNA-binding transcription factor activity
HV164_RS11725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV164_RS11735	COG2010	Cytochrome c
HV164_RS11740	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HV164_RS11750	COG1012	belongs to the aldehyde dehydrogenase family
HV164_RS11765	COG1113	amino acid transport
HV164_RS11770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV164_RS11775	COG0129	dihydroxy-acid dehydratase activity
HV164_RS11780	COG2271	Major facilitator Superfamily
HV164_RS11785	COG0800	Aldolase
HV164_RS11790	COG3734	2-keto-3-deoxy-galactonokinase
HV164_RS11805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV164_RS11815	COG0765	amino acid transport
HV164_RS11820	COG0765	amino acid transport
HV164_RS11830	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HV164_RS11835	COG0437	4 iron, 4 sulfur cluster binding
HV164_RS11845	COG2414	aldehyde ferredoxin oxidoreductase
HV164_RS11850	COG0437	4 iron, 4 sulfur cluster binding
HV164_RS11885	COG1464	Belongs to the NlpA lipoprotein family
HV164_RS11890	COG2011	ABC-type metal ion transport system permease component
HV164_RS11910	COG1376	ErfK ybiS ycfS ynhG family protein
HV164_RS11925	COG0719	Fe-S assembly protein
HV164_RS11930	COG0396	ATPase activity
HV164_RS11935	COG0719	Fe-S assembly protein
HV164_RS11940	COG0316	Belongs to the HesB IscA family
HV164_RS11960	COG2050	protein possibly involved in aromatic compounds catabolism
HV164_RS11965	COG0277	FAD linked oxidase domain protein
HV164_RS11965	COG0247	lactate metabolic process
HV164_RS11970	COG0628	permease
HV164_RS11980	COG1472	Belongs to the glycosyl hydrolase 3 family
HV164_RS11990	COG0738	Major facilitator superfamily
HV164_RS11995	COG2271	Major facilitator Superfamily
HV164_RS12010	COG4670	ketone body catabolic process
HV164_RS12015	COG1960	acyl-CoA dehydrogenase activity
HV164_RS12020	COG1917	Cupin 2, conserved barrel domain protein
HV164_RS12020	COG2207	Transcriptional regulator
HV164_RS12025	COG2086	electron transfer activity
HV164_RS12030	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HV164_RS12035	COG0644	oxidoreductase
HV164_RS12040	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HV164_RS12045	COG0318	PFAM AMP-dependent synthetase and ligase
HV164_RS12050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV164_RS12050	COG0574	Belongs to the PEP-utilizing enzyme family
HV164_RS12065	COG4256	Hemin uptake protein
HV164_RS12070	COG4771	TonB-dependent receptor
HV164_RS12075	COG3720	iron ion transport
HV164_RS12080	COG4558	Periplasmic binding protein
HV164_RS12085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV164_RS12105	COG0791	NLP P60 protein
HV164_RS12115	COG0386	Belongs to the glutathione peroxidase family
HV164_RS12135	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HV164_RS12150	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HV164_RS12175	COG3137	Salt-induced outer membrane protein
HV164_RS12180	COG1105	Belongs to the carbohydrate kinase PfkB family
HV164_RS12185	COG3001	Fructosamine kinase
HV164_RS12195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV164_RS12200	COG1028	Short-chain dehydrogenase reductase Sdr
HV164_RS12205	COG1988	membrane-bound metal-dependent
HV164_RS12220	COG0753	catalase activity
HV164_RS12230	COG1486	melibiose metabolic process
HV164_RS12235	COG2169	Transcriptional regulator
HV164_RS12235	COG1917	Cupin 2, conserved barrel domain protein
HV164_RS12240	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV164_RS12245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV164_RS12250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV164_RS12255	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV164_RS12265	COG0322	excinuclease ABC activity
HV164_RS12275	COG3678	ATP-independent chaperone mediated protein folding
HV164_RS12305	COG0708	Exodeoxyribonuclease III
HV164_RS12310	COG0398	Pfam SNARE associated Golgi protein
HV164_RS12315	COG0398	Pfam SNARE associated Golgi protein
HV164_RS12320	COG4134	Bacterial extracellular solute-binding protein
HV164_RS12325	COG4135	transport system, permease component
HV164_RS12330	COG4136	ATPase activity
HV164_RS12335	COG2897	thiosulfate sulfurtransferase activity
HV164_RS12340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HV164_RS12345	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV164_RS12350	COG0494	nUDIX hydrolase
HV164_RS12365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HV164_RS12370	COG0709	Synthesizes selenophosphate from selenide and ATP
HV164_RS12375	COG0778	Nitroreductase
HV164_RS12380	COG0616	signal peptide processing
HV164_RS12385	COG0252	asparaginase activity
HV164_RS12390	COG1335	isochorismatase
HV164_RS12400	COG3139	Protein of unknown function (DUF1315)
HV164_RS12420	COG0656	L-ascorbic acid biosynthetic process
HV164_RS12430	COG3713	MltA-interacting MipA family protein
HV164_RS12435	COG2766	serine protein kinase
HV164_RS12445	COG0110	maltose O-acetyltransferase activity
HV164_RS12455	COG2226	methyltransferase
HV164_RS12460	COG2199	diguanylate cyclase activity
HV164_RS12465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV164_RS12475	COG2207	Transcriptional regulator
HV164_RS12480	COG2807	transmembrane transport
HV164_RS12485	COG0504	CTP synthase activity
HV164_RS12490	COG3189	MarR family transcriptional regulator
HV164_RS12495	COG3042	response to heat
HV164_RS12500	COG2199	diguanylate cyclase activity
HV164_RS12500	COG2203	Gaf domain
HV164_RS12515	COG2261	transglycosylase associated protein
HV164_RS12520	COG3383	formate dehydrogenase (NAD+) activity
HV164_RS12535	COG3615	Tellurite resistance protein tehB
HV164_RS12545	COG1335	isochorismatase
HV164_RS12550	COG3443	Belongs to the bacterial solute-binding protein 9 family
HV164_RS12555	COG1124	(ABC) transporter
HV164_RS12565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV164_RS12570	COG0601	transmembrane transport
HV164_RS12575	COG0747	negative chemotaxis
HV164_RS12580	COG4771	TonB-dependent receptor
HV164_RS12590	COG2194	sulfuric ester hydrolase activity
HV164_RS12595	COG0538	isocitrate dehydrogenase activity
HV164_RS12615	COG3179	chitinase
HV164_RS12635	COG1403	HNH endonuclease
HV164_RS12690	COG0582	viral genome integration into host DNA
HV164_RS12695	COG0538	isocitrate dehydrogenase activity
HV164_RS12750	COG4220	transposase activity
HV164_RS12775	COG3772	lysozyme
HV164_RS12785	COG1278	Cold shock
HV164_RS12790	COG1278	Cold shock
HV164_RS12835	COG0582	viral genome integration into host DNA
HV164_RS12845	COG1074	ATP-dependent DNA helicase activity
HV164_RS12850	COG0538	isocitrate dehydrogenase activity
HV164_RS12855	COG1187	pseudouridine synthase activity
HV164_RS12880	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HV164_RS12895	COG2850	peptidyl-arginine hydroxylation
HV164_RS12920	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV164_RS12960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV164_RS12995	COG1177	transmembrane transport
HV164_RS13000	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV164_RS13010	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HV164_RS13020	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV164_RS13025	COG1136	(ABC) transporter
HV164_RS13030	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV164_RS13035	COG4763	Acyl-transferase
HV164_RS13040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HV164_RS13045	COG1376	ErfK ybiS ycfS ynhG family protein
HV164_RS13045	COG1388	LysM domain
HV164_RS13055	COG1309	transcriptional regulator
HV164_RS13060	COG3134	Outer membrane lipoprotein
HV164_RS13065	COG1252	NADH dehydrogenase
HV164_RS13090	COG5633	Lipoprotein
HV164_RS13095	COG0537	adenosine 5'-monophosphoramidase activity
HV164_RS13100	COG4773	Receptor
HV164_RS13105	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV164_RS13110	COG3327	negative regulation of DNA-templated transcription, initiation
HV164_RS13115	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HV164_RS13120	COG0183	Belongs to the thiolase family
HV164_RS13125	COG2050	protein possibly involved in aromatic compounds catabolism
HV164_RS13130	COG1250	3-hydroxyacyl-CoA dehydrogenase
HV164_RS13135	COG1024	Enoyl-CoA hydratase
HV164_RS13140	COG1024	Enoyl-CoA hydratase
HV164_RS13145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV164_RS13150	COG2151	metal-sulfur cluster biosynthetic enzyme
HV164_RS13155	COG3396	Phenylacetate-CoA oxygenase
HV164_RS13160	COG3460	Phenylacetate-CoA oxygenase
HV164_RS13165	COG3396	Phenylacetate-CoA oxygenase
HV164_RS13170	COG2030	dehydratase
HV164_RS13170	COG1012	belongs to the aldehyde dehydrogenase family
HV164_RS13175	COG0800	Aldolase
HV164_RS13180	COG0129	dihydroxy-acid dehydratase activity
HV164_RS13185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HV164_RS13190	COG1737	Transcriptional regulator
HV164_RS13200	COG1560	Kdo2-lipid A biosynthetic process
HV164_RS13205	COG0739	heme binding
HV164_RS13210	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HV164_RS13220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV164_RS13240	COG0217	transcriptional regulatory protein
HV164_RS13245	COG0494	nUDIX hydrolase
HV164_RS13255	COG1335	isochorismatase
HV164_RS13260	COG1801	Protein of unknown function DUF72
HV164_RS13265	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HV164_RS13285	COG3102	Protein conserved in bacteria
HV164_RS13300	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HV164_RS13330	COG0745	RESPONSE REGULATOR receiver
HV164_RS13355	COG1301	dicarboxylic acid transport
HV164_RS13360	COG0835	chemotaxis
HV164_RS13405	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV164_RS13410	COG1129	ABC transporter
HV164_RS13415	COG1879	ABC-type sugar transport system periplasmic component
HV164_RS13425	COG1528	Iron-storage protein
HV164_RS13435	COG0477	Major facilitator Superfamily
HV164_RS13450	COG1528	Iron-storage protein
HV164_RS13460	COG0814	amino acid
HV164_RS13465	COG3318	Belongs to the UPF0149 family
HV164_RS13465	COG3012	SEC-C Motif Domain Protein
HV164_RS13470	COG2608	mercury ion transmembrane transporter activity
HV164_RS13480	COG1305	Transglutaminase-like
HV164_RS13535	COG2197	response regulator
HV164_RS13545	COG2197	response regulator
HV164_RS13560	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HV164_RS13600	COG0366	Alpha amylase catalytic
HV164_RS13615	COG0425	Belongs to the sulfur carrier protein TusA family
HV164_RS13645	COG2882	bacterial-type flagellum organization
HV164_RS13705	COG5475	Uncharacterized small protein (DUF2158)
HV164_RS13710	COG2354	Protein conserved in bacteria
HV164_RS13715	COG0697	spore germination
HV164_RS13720	COG3727	T/G mismatch-specific endonuclease activity
HV164_RS13725	COG0270	DNA (cytosine-5-)-methyltransferase activity
HV164_RS13730	COG1418	mRNA catabolic process
HV164_RS13735	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV164_RS13740	COG1278	Cold shock
HV164_RS13745	COG1278	Cold shock
HV164_RS13765	COG1278	Cold shock
HV164_RS13790	COG1403	HNH endonuclease
HV164_RS13795	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HV164_RS13815	COG3272	Protein of unknown function (DUF1722)
HV164_RS13855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV164_RS13870	COG2135	peptidase activity
HV164_RS13880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HV164_RS13905	COG5301	cellulose 1,4-beta-cellobiosidase activity
HV164_RS13985	COG4695	Portal protein
HV164_RS14065	COG1403	HNH endonuclease
HV164_RS14075	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HV164_RS14090	COG1846	Transcriptional regulator
HV164_RS14120	COG5532	Uncharacterized conserved protein (DUF2303)
HV164_RS14190	COG0583	DNA-binding transcription factor activity
HV164_RS14205	COG0477	Major facilitator Superfamily
HV164_RS14210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HV164_RS14225	COG0084	hydrolase, TatD family'
HV164_RS14230	COG0470	DNA polymerase III
HV164_RS14240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HV164_RS14245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV164_RS14250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV164_RS14260	COG1028	Short-chain dehydrogenase reductase Sdr
HV164_RS14285	COG1399	metal-binding, possibly nucleic acid-binding protein
HV164_RS14295	COG0564	pseudouridine synthase activity
HV164_RS14300	COG1530	ribonuclease E activity
HV164_RS14305	COG0583	DNA-binding transcription factor activity
HV164_RS14310	COG2814	Major facilitator Superfamily
HV164_RS14340	COG4786	Flagellar basal body rod
HV164_RS14345	COG4787	bacterial-type flagellum-dependent cell motility
HV164_RS14360	COG1558	bacterial-type flagellum-dependent cell motility
HV164_RS14400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV164_RS14470	COG3038	cytochrome b561
HV164_RS14485	COG1560	Kdo2-lipid A biosynthetic process
HV164_RS14500	COG5645	(Lipo)protein
HV164_RS14520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV164_RS14575	COG3381	protein complex oligomerization
HV164_RS14595	COG1702	phosphate starvation-inducible protein PhoH
HV164_RS14620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HV164_RS14625	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV164_RS14625	COG0506	proline dehydrogenase activity
HV164_RS14625	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV164_RS14630	COG3755	Protein conserved in bacteria
HV164_RS14635	COG1309	transcriptional regulator
HV164_RS14640	COG3729	General stress protein
HV164_RS14660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HV164_RS14665	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HV164_RS14665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HV164_RS14670	COG4232	protein-disulfide reductase activity
HV164_RS14700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV164_RS14705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV164_RS14710	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HV164_RS14715	COG1757	Na H antiporter
HV164_RS14720	COG1609	Transcriptional regulator
HV164_RS14730	COG2814	Major facilitator Superfamily
HV164_RS14755	COG0656	L-ascorbic acid biosynthetic process
HV164_RS14770	COG0670	Belongs to the BI1 family
HV164_RS14780	COG2920	part of a sulfur-relay system
HV164_RS14800	COG1832	CoA-binding protein
HV164_RS14815	COG0210	DNA helicase
HV164_RS14820	COG3304	Inner membrane component domain
HV164_RS14825	COG1289	transmembrane transporter activity
HV164_RS14830	COG3070	regulator of competence-specific genes
HV164_RS14850	COG1067	ATP-dependent peptidase activity
HV164_RS14860	COG3130	regulation of translation
HV164_RS14865	COG3009	Protein conserved in bacteria
HV164_RS14870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV164_RS14870	COG3008	intermembrane lipid transfer
HV164_RS14875	COG2995	paraquat-inducible protein a
HV164_RS14880	COG0488	(ABC) transporter
HV164_RS14890	COG3217	Mosc domain protein beta barrel domain protein
HV164_RS14890	COG0633	Ferredoxin
HV164_RS14905	COG0431	NADPH-dependent FMN reductase
HV164_RS14910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV164_RS14920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV164_RS14930	COG0308	aminopeptidase N
HV164_RS14950	COG1448	Aminotransferase
HV164_RS14955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV164_RS14960	COG3108	Peptidase M15
HV164_RS14965	COG2989	Protein conserved in bacteria
HV164_RS14975	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HV164_RS14985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HV164_RS14990	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV164_RS14995	COG3173	Aminoglycoside phosphotransferase
HV164_RS15010	COG3214	Protein conserved in bacteria
HV164_RS15015	COG1663	tetraacyldisaccharide 4'-kinase activity
HV164_RS15025	COG0658	competence protein
HV164_RS15025	COG2333	competence protein COMEC
HV164_RS15030	COG0776	regulation of translation
HV164_RS15035	COG0539	negative regulation of cytoplasmic translation
HV164_RS15055	COG2323	membrane
HV164_RS15060	COG1944	ATP diphosphatase activity
HV164_RS15065	COG2116	formate transmembrane transporter activity
HV164_RS15070	COG1882	Formate acetyltransferase
HV164_RS15075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV164_RS15085	COG0531	amino acid
HV164_RS15095	COG3302	dmso reductase anchor subunit
HV164_RS15100	COG0437	4 iron, 4 sulfur cluster binding
HV164_RS15105	COG0243	molybdopterin cofactor binding
HV164_RS15115	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HV164_RS15125	COG1178	ABC-type Fe3 transport system permease component
HV164_RS15125	COG1674	ftsk spoiiie
HV164_RS15130	COG1522	sequence-specific DNA binding
HV164_RS15135	COG0492	ferredoxin-NADP+ reductase activity
HV164_RS15140	COG4988	ABC transporter
HV164_RS15145	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HV164_RS15160	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HV164_RS15165	COG0583	DNA-binding transcription factor activity
HV164_RS15175	COG1335	isochorismatase
HV164_RS15195	COG1177	transmembrane transport
HV164_RS15200	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV164_RS15205	COG3842	ATPase activity
HV164_RS15210	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV164_RS15250	COG1028	Short-chain dehydrogenase reductase Sdr
HV164_RS15255	COG3226	Transcriptional regulator
HV164_RS15260	COG0738	Major facilitator superfamily
HV164_RS15265	COG0561	phosphatase activity
HV164_RS15275	COG2814	Major facilitator Superfamily
HV164_RS15280	COG0671	phosphoesterase, PA-phosphatase related
HV164_RS15285	COG1349	DNA-binding transcription factor activity
HV164_RS15290	COG1686	Belongs to the peptidase S11 family
HV164_RS15295	COG0625	glutathione transferase activity
HV164_RS15300	COG2133	pyrroloquinoline quinone binding
HV164_RS15310	COG0583	DNA-binding transcription factor activity
HV164_RS15315	COG0058	SHG alpha-glucan phosphorylase activity
HV164_RS15345	COG1446	asparaginase
HV164_RS15350	COG0303	'Molybdopterin
HV164_RS15355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV164_RS15360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HV164_RS15365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV164_RS15370	COG1882	Formate acetyltransferase
HV164_RS15375	COG0561	phosphatase activity
HV164_RS15395	COG0488	(ABC) transporter
HV164_RS15400	COG1376	ErfK ybiS ycfS ynhG family protein
HV164_RS15405	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV164_RS15420	COG2194	sulfuric ester hydrolase activity
HV164_RS15425	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HV164_RS15440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV164_RS15445	COG0765	amino acid transport
HV164_RS15450	COG1126	abc transporter atp-binding protein
HV164_RS15455	COG0668	transmembrane transport
HV164_RS15480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HV164_RS15490	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HV164_RS15495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HV164_RS15505	COG0513	Belongs to the DEAD box helicase family
HV164_RS15510	COG1309	transcriptional regulator
HV164_RS15520	COG1131	(ABC) transporter
HV164_RS15525	COG0842	Transport permease protein
HV164_RS15530	COG0842	Transport permease protein
HV164_RS15540	COG3568	Endonuclease Exonuclease Phosphatase
HV164_RS15545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV164_RS15550	COG0392	lysyltransferase activity
HV164_RS15555	COG0670	Belongs to the BI1 family
HV164_RS15560	COG0314	molybdopterin synthase activity
HV164_RS15565	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HV164_RS15575	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV164_RS15625	COG1881	PFAM PEBP family protein
HV164_RS15655	COG4677	pectinesterase activity
HV164_RS15660	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HV164_RS15665	COG0471	metal ion transport
HV164_RS15670	COG2828	Protein conserved in bacteria
HV164_RS15675	COG0583	DNA-binding transcription factor activity
HV164_RS15685	COG0561	phosphatase activity
HV164_RS15695	COG4149	molybdate abc transporter
HV164_RS15700	COG0725	ABC transporter, periplasmic molybdate-binding protein
HV164_RS15710	COG3585	molybdate ion transport
HV164_RS15710	COG2005	Transcriptional regulator
HV164_RS15715	COG1119	ATPase activity
HV164_RS15720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HV164_RS15725	COG1085	galactose-1-phosphate uridylyltransferase
HV164_RS15735	COG2017	converts alpha-aldose to the beta-anomer
HV164_RS15745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV164_RS15755	COG1230	cation diffusion facilitator family transporter
HV164_RS15760	COG3201	nicotinamide mononucleotide transporter
HV164_RS15800	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HV164_RS15805	COG2885	chlorophyll binding
HV164_RS15815	COG3064	Membrane
HV164_RS15820	COG0848	biopolymer transport protein
HV164_RS15825	COG0811	peptide transport
HV164_RS15830	COG0824	Thioesterase
HV164_RS15835	COG3790	cyd operon protein YbgE
HV164_RS15840	COG4890	Cyd operon protein YbgT
HV164_RS15845	COG1294	oxidase, subunit
HV164_RS15850	COG1271	oxidase subunit
HV164_RS15855	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV164_RS15865	COG4865	methylaspartate mutase activity
HV164_RS15870	COG3799	methylaspartate ammonia-lyase activity
HV164_RS15885	COG1301	dicarboxylic acid transport
HV164_RS15895	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV164_RS15895	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV164_RS15905	COG0583	DNA-binding transcription factor activity
HV164_RS15910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HV164_RS15910	COG1648	precorrin-2 dehydrogenase activity
HV164_RS15920	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV164_RS15930	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV164_RS15935	COG0567	Dehydrogenase, E1 component
HV164_RS15940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV164_RS15945	COG1053	succinate dehydrogenase
HV164_RS15950	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HV164_RS15955	COG2009	succinate dehydrogenase
HV164_RS15965	COG3180	Ammonia monooxygenase
HV164_RS16000	COG1984	allophanate hydrolase subunit 2
HV164_RS16005	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HV164_RS16010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HV164_RS16030	COG3272	Protein of unknown function (DUF1722)
HV164_RS16060	COG2205	protein histidine kinase activity
HV164_RS16065	COG0745	RESPONSE REGULATOR receiver
HV164_RS16070	COG0033	Phosphoglucomutase
HV164_RS16080	COG0596	Alpha beta hydrolase
HV164_RS16100	COG0735	belongs to the Fur family
HV164_RS16105	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HV164_RS16105	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV164_RS16120	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV164_RS16125	COG3715	PTS system
HV164_RS16130	COG3716	PTS system mannose fructose sorbose family IID component
HV164_RS16150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV164_RS16150	COG2190	(PTS) system
HV164_RS16150	COG1263	PTS System
HV164_RS16160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV164_RS16165	COG1940	carbohydrate kinase activity
HV164_RS16165	COG1846	Transcriptional regulator
HV164_RS16170	COG0647	UMP catabolic process
HV164_RS16175	COG0367	asparagine synthase
HV164_RS16215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV164_RS16225	COG1702	phosphate starvation-inducible protein PhoH
HV164_RS16230	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HV164_RS16255	COG0765	amino acid transport
HV164_RS16260	COG0765	amino acid transport
HV164_RS16265	COG1126	abc transporter atp-binding protein
HV164_RS16275	COG2888	peptidyl-tyrosine sulfation
HV164_RS16290	COG1466	dna polymerase III delta subunit
HV164_RS16300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HV164_RS16310	COG0799	negative regulation of ribosome biogenesis
HV164_RS16320	COG0768	penicillin binding
HV164_RS16325	COG0772	Belongs to the SEDS family
HV164_RS16330	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV164_RS16335	COG1686	Belongs to the peptidase S11 family
HV164_RS16360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV164_RS16380	COG3069	C4-dicarboxylate transmembrane transporter activity
HV164_RS16385	COG4565	transcriptional regulatory protein
HV164_RS16390	COG3290	protein histidine kinase activity
HV164_RS16395	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HV164_RS16405	COG2301	Belongs to the HpcH HpaI aldolase family
HV164_RS16410	COG3051	citrate lyase alpha subunit
HV164_RS16425	COG0471	metal ion transport
HV164_RS16430	COG3719	Belongs to the RNase T2 family
HV164_RS16435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV164_RS16445	COG3634	alkyl hydroperoxide reductase activity
HV164_RS16455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HV164_RS16460	COG0583	DNA-binding transcription factor activity
HV164_RS16465	COG3969	phosphoadenosine phosphosulfate
HV164_RS16470	COG1475	DNA binding
HV164_RS16475	COG0436	Aminotransferase
HV164_RS16480	COG0371	Dehydrogenase
HV164_RS16485	COG2879	small protein
HV164_RS16490	COG1966	Carbon starvation protein
HV164_RS16500	COG1028	Short-chain dehydrogenase reductase Sdr
HV164_RS16505	COG3433	isochorismatase activity
HV164_RS16505	COG1535	isochorismatase
HV164_RS16510	COG1021	2,3-dihydroxybenzoate-AMP ligase
HV164_RS16515	COG1169	isochorismate synthase
HV164_RS16520	COG4592	Periplasmic binding protein
HV164_RS16530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV164_RS16535	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV164_RS16540	COG1120	ATPase activity
HV164_RS16545	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HV164_RS16550	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HV164_RS16550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HV164_RS16555	COG3251	PFAM MbtH domain protein
HV164_RS16560	COG2382	esterase
HV164_RS16565	COG4771	TonB-dependent receptor
HV164_RS16570	COG2977	Belongs to the P-Pant transferase superfamily
HV164_RS16610	COG2315	Protein conserved in bacteria
HV164_RS16620	COG0668	transmembrane transport
HV164_RS16640	COG2211	Major facilitator Superfamily
HV164_RS16645	COG1113	amino acid transport
HV164_RS16670	COG5001	Diguanylate cyclase
HV164_RS16670	COG3300	MHYT domain
HV164_RS16685	COG3059	membrane
HV164_RS16695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV164_RS16700	COG2207	Transcriptional regulator
HV164_RS16705	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV164_RS16710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV164_RS16715	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV164_RS16720	COG1538	Outer membrane efflux protein
HV164_RS16725	COG0745	RESPONSE REGULATOR receiver
HV164_RS16730	COG5002	protein histidine kinase activity
HV164_RS16755	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HV164_RS16755	COG0321	lipoyl(octanoyl) transferase activity
HV164_RS16845	COG2501	S4 domain
HV164_RS16850	COG1988	membrane-bound metal-dependent
HV164_RS16860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HV164_RS16870	COG2373	Large extracellular alpha-helical protein
HV164_RS16870	COG4932	domain protein
HV164_RS16870	COG1388	LysM domain
HV164_RS16875	COG1388	LysM domain
HV164_RS16885	COG0745	RESPONSE REGULATOR receiver
HV164_RS16895	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HV164_RS16900	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HV164_RS16910	COG2011	ABC-type metal ion transport system permease component
HV164_RS16920	COG1464	Belongs to the NlpA lipoprotein family
HV164_RS16930	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HV164_RS16935	COG4181	ATPase activity
HV164_RS16940	COG2755	lipolytic protein G-D-S-L family
HV164_RS16945	COG0300	oxidoreductase activity
HV164_RS16950	COG3118	belongs to the thioredoxin family
HV164_RS16955	COG0390	transport system, permease component
HV164_RS16960	COG4619	ABC transporter
HV164_RS16965	COG0330	HflC and HflK could
HV164_RS16970	COG1585	Membrane protein implicated in regulation of membrane protease activity
HV164_RS16990	COG2217	Heavy metal translocating P-type atpase
HV164_RS16995	COG3735	TraB family
HV164_RS17010	COG2223	nitrite transmembrane transporter activity
HV164_RS17015	COG4651	solute:proton antiporter activity
HV164_RS17015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HV164_RS17020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV164_RS17045	COG1882	Formate acetyltransferase
HV164_RS17050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV164_RS17050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV164_RS17050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV164_RS17085	COG2832	Protein of unknown function (DUF454)
HV164_RS17090	COG3923	Primosomal replication protein n
HV164_RS17100	COG3264	Mechanosensitive ion channel
HV164_RS17100	COG1196	nuclear chromosome segregation
HV164_RS17105	COG1309	transcriptional regulator
HV164_RS17110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV164_RS17115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV164_RS17145	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV164_RS17150	COG5507	3-demethylubiquinone-9 3-methyltransferase
HV164_RS17155	COG2364	Membrane
HV164_RS17160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV164_RS17190	COG3695	enzyme binding
HV164_RS17195	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HV164_RS17200	COG1946	Acyl-CoA thioesterase
HV164_RS17205	COG0004	ammonium transporteR
HV164_RS17210	COG0347	Belongs to the P(II) protein family
HV164_RS17215	COG1132	(ABC) transporter
HV164_RS17220	COG1132	(ABC) transporter
HV164_RS17225	COG1522	sequence-specific DNA binding
HV164_RS17240	COG4533	DNA binding
HV164_RS17250	COG0824	Thioesterase
HV164_RS17255	COG1555	photosystem II stabilization
HV164_RS17260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV164_RS17265	COG0776	regulation of translation
HV164_RS17270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HV164_RS17290	COG0271	Belongs to the BolA IbaG family
HV164_RS17295	COG3056	Lipoprotein
HV164_RS17300	COG2223	nitrite transmembrane transporter activity
HV164_RS17305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HV164_RS17310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HV164_RS17315	COG1845	cytochrome c oxidase, subunit III
HV164_RS17320	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HV164_RS17330	COG2814	Major facilitator Superfamily
HV164_RS17365	COG0142	geranyltranstransferase activity
HV164_RS17375	COG0667	Aldo Keto reductase
HV164_RS17380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HV164_RS17385	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HV164_RS17400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV164_RS17400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV164_RS17410	COG4238	major outer membrane lipoprotein
HV164_RS17420	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV164_RS17425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV164_RS17430	COG1862	Preprotein translocase
HV164_RS17440	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HV164_RS17450	COG0450	alkyl hydroperoxide reductase
HV164_RS17455	COG0366	Alpha amylase catalytic
HV164_RS17470	COG5002	protein histidine kinase activity
HV164_RS17480	COG0420	3'-5' exonuclease activity
HV164_RS17485	COG0419	ATPase involved in DNA repair
HV164_RS17490	COG2814	Major facilitator Superfamily
HV164_RS17495	COG1940	carbohydrate kinase activity
HV164_RS17505	COG3123	guanosine phosphorylase activity
HV164_RS17510	COG4126	flavin adenine dinucleotide binding
HV164_RS17530	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HV164_RS17535	COG3706	GGDEF domain
HV164_RS17545	COG1785	Belongs to the alkaline phosphatase family
HV164_RS17560	COG1181	Belongs to the D-alanine--D-alanine ligase family
HV164_RS17580	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HV164_RS17585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HV164_RS17590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV164_RS17595	COG3468	outer membrane autotransporter barrel domain protein
HV164_RS17600	COG0113	porphobilinogen synthase activity
HV164_RS17605	COG2175	clavaminate synthase activity
HV164_RS17610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV164_RS17615	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HV164_RS17620	COG4521	taurine ABC transporter
HV164_RS17635	COG2271	Major facilitator Superfamily
HV164_RS17640	COG1840	ABC-type Fe3 transport system, periplasmic component
HV164_RS17650	COG3842	ATPase activity
HV164_RS17670	COG2040	homocysteine
HV164_RS17675	COG0833	amino acid
HV164_RS17680	COG2814	Major facilitator Superfamily
HV164_RS17715	COG1414	Transcriptional regulator
HV164_RS17720	COG5001	Diguanylate cyclase
HV164_RS17720	COG3300	MHYT domain
HV164_RS17745	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HV164_RS17760	COG1609	Transcriptional regulator
HV164_RS17770	COG2223	nitrite transmembrane transporter activity
HV164_RS17780	COG2079	MmgE PrpD family protein
HV164_RS17785	COG0372	Belongs to the citrate synthase family
HV164_RS17795	COG3829	transcription factor binding
HV164_RS17805	COG1280	lysine exporter protein (LysE YggA)
HV164_RS17810	COG3706	GGDEF domain
HV164_RS17815	COG0348	domain, Protein
HV164_RS17835	COG0693	protein deglycase activity
HV164_RS17880	COG1136	(ABC) transporter
HV164_RS17890	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HV164_RS17900	COG0531	amino acid
HV164_RS17905	COG0174	glutamine synthetase
HV164_RS17910	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HV164_RS17915	COG1917	Cupin 2, conserved barrel domain protein
HV164_RS17915	COG1396	sequence-specific DNA binding
HV164_RS17920	COG1012	belongs to the aldehyde dehydrogenase family
HV164_RS17925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HV164_RS17995	COG0582	viral genome integration into host DNA
HV164_RS18035	COG2195	Cleaves the N-terminal amino acid of tripeptides
HV164_RS18060	COG0791	NLP P60 protein
HV164_RS18065	COG3034	peptidoglycan biosynthetic process
HV164_RS18070	COG0121	glutamine amidotransferase
HV164_RS18080	COG1960	acyl-CoA dehydrogenase activity
HV164_RS18090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV164_RS18105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV164_RS18115	COG2226	methyltransferase
HV164_RS18125	COG1388	LysM domain
HV164_RS18125	COG0741	lytic transglycosylase activity
HV164_RS18130	COG2226	methyltransferase
HV164_RS18140	COG2814	Major facilitator Superfamily
HV164_RS18145	COG0583	DNA-binding transcription factor activity
HV164_RS18180	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HV164_RS18190	COG2011	ABC-type metal ion transport system permease component
HV164_RS18195	COG1464	Belongs to the NlpA lipoprotein family
HV164_RS18205	COG1720	tRNA m6t6A37 methyltransferase activity
HV164_RS18215	COG3015	lipoprotein NlpE involved in copper resistance
HV164_RS18220	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HV164_RS18235	COG4568	rho-dependent transcription termination
HV164_RS18245	COG0346	lactoylglutathione lyase activity
HV164_RS18285	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HV164_RS18290	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HV164_RS18305	COG0575	Belongs to the CDS family
HV164_RS18315	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HV164_RS18360	COG3835	regulator
HV164_RS18365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV164_RS18385	COG2860	membrane
HV164_RS18410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV164_RS18415	COG1120	ATPase activity
HV164_RS18420	COG4774	siderophore transport
HV164_RS18425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HV164_RS18430	COG1643	Atp-dependent helicase
HV164_RS18435	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HV164_RS18455	COG0617	tRNA 3'-terminal CCA addition
HV164_RS18460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HV164_RS18470	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HV164_RS18480	COG3539	Fimbrial protein
HV164_RS18485	COG3121	Chaperone
HV164_RS18490	COG3188	usher protein
HV164_RS18500	COG3539	Fimbrial protein
HV164_RS18510	COG3539	Fimbrial protein
HV164_RS18515	COG0726	polysaccharide deacetylase
HV164_RS18520	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV164_RS18525	COG0842	Transport permease protein
HV164_RS18530	COG1131	(ABC) transporter
HV164_RS18535	COG0288	reversible hydration of carbon dioxide
HV164_RS18540	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HV164_RS18560	COG1609	Transcriptional regulator
HV164_RS18565	COG2814	Major facilitator Superfamily
HV164_RS18585	COG3064	Membrane
HV164_RS18595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV164_RS18600	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV164_RS18605	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HV164_RS18610	COG2186	Transcriptional regulator
HV164_RS18620	COG2211	Major facilitator Superfamily
HV164_RS18625	COG3940	Belongs to the glycosyl hydrolase 43 family
HV164_RS18630	COG3725	Membrane protein required for beta-lactamase induction
HV164_RS18645	COG4969	Belongs to the N-Me-Phe pilin family
HV164_RS18650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HV164_RS18655	COG1459	type II secretion system
HV164_RS18665	COG0237	dephospho-CoA kinase activity
HV164_RS18680	COG0494	nUDIX hydrolase
HV164_RS18700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HV164_RS18705	COG0849	cell division
HV164_RS18715	COG1181	Belongs to the D-alanine--D-alanine ligase family
HV164_RS18730	COG0772	Belongs to the SEDS family
HV164_RS18745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HV164_RS18750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HV164_RS18755	COG0768	penicillin binding
HV164_RS18785	COG0028	Belongs to the TPP enzyme family
HV164_RS18805	COG0473	3-isopropylmalate dehydrogenase activity
HV164_RS18820	COG2814	Major facilitator Superfamily
HV164_RS18840	COG1178	ABC-type Fe3 transport system permease component
HV164_RS18850	COG0586	Pfam SNARE associated Golgi protein
HV164_RS18870	COG0235	Class ii aldolase
HV164_RS18880	COG0417	DNA replication proofreading
HV164_RS18890	COG0564	pseudouridine synthase activity
HV164_RS18900	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HV164_RS18905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV164_RS18950	COG2271	Major facilitator Superfamily
HV164_RS18960	COG0644	oxidoreductase
HV164_RS19015	COG0505	Belongs to the CarA family
HV164_RS19025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HV164_RS19045	COG1047	Peptidyl-prolyl cis-trans
HV164_RS19060	COG0196	riboflavin kinase activity
HV164_RS19070	COG0583	DNA-binding transcription factor activity
HV164_RS19085	COG0443	Heat shock 70 kDa protein
HV164_RS19095	COG1584	GPR1 FUN34 yaaH family protein
HV164_RS19100	COG0477	Major facilitator Superfamily
HV164_RS19105	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV164_RS19115	COG1115	amino acid carrier protein
HV164_RS19125	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HV164_RS19135	COG0460	homoserine dehydrogenase
HV164_RS19135	COG0527	aspartate kinase activity
HV164_RS19145	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HV164_RS19155	COG0745	RESPONSE REGULATOR receiver
HV164_RS19160	COG4452	Inner membrane protein CreD
HV164_RS19165	COG2205	protein histidine kinase activity
HV164_RS19170	COG0745	RESPONSE REGULATOR receiver
HV164_RS19175	COG3045	CreA protein
HV164_RS19180	COG3708	Transcriptional regulator
HV164_RS19180	COG2207	Transcriptional regulator
HV164_RS19200	COG0741	lytic transglycosylase activity
HV164_RS19205	COG0488	(ABC) transporter
HV164_RS19220	COG0560	Phosphoserine phosphatase
HV164_RS19225	COG3726	membrane protein affecting hemolysin expression
HV164_RS19255	COG1328	CTP reductase activity
HV164_RS19260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV164_RS19265	COG0084	hydrolase, TatD family'
HV164_RS19270	COG4667	esterase of the alpha-beta hydrolase superfamily
HV164_RS19275	COG5487	UPF0391 membrane protein
HV164_RS19280	COG2823	Periplasmic or secreted lipoprotein
HV164_RS19290	COG1011	Hydrolase
HV164_RS19295	COG0456	acetyltransferase
HV164_RS19300	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HV164_RS19330	COG3706	GGDEF domain
HV164_RS19335	COG4114	ferric iron reductase
HV164_RS19340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV164_RS19345	COG2197	response regulator
HV164_RS19350	COG2197	response regulator
HV164_RS19355	COG2966	Psort location CytoplasmicMembrane, score
HV164_RS19370	COG1484	DNA-dependent DNA replication
HV164_RS19385	COG1063	alcohol dehydrogenase
HV164_RS19390	COG1802	Transcriptional regulator
HV164_RS19395	COG2271	Major facilitator Superfamily
HV164_RS19400	COG0840	transmembrane signaling receptor activity
HV164_RS19405	COG1966	Carbon starvation protein
HV164_RS19410	COG2879	small protein
HV164_RS19415	COG0523	cobalamin synthesis protein
HV164_RS19445	COG5457	Domain of unknown function (DUF1127)
HV164_RS19450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV164_RS19455	COG5464	transposase or invertase
HV164_RS19465	COG0626	cystathionine gamma-synthase activity
HV164_RS19470	COG1301	dicarboxylic acid transport
HV164_RS19480	COG2733	membrane
HV164_RS19490	COG0477	Major facilitator Superfamily
HV164_RS19510	COG1556	Lactate utilization protein
HV164_RS19515	COG1139	Iron-sulfur cluster binding protein
HV164_RS19520	COG0247	lactate metabolic process
HV164_RS19525	COG0277	FAD linked oxidase domain protein
HV164_RS19530	COG1620	l-lactate permease
HV164_RS19560	COG0531	amino acid
HV164_RS19565	COG1012	belongs to the aldehyde dehydrogenase family
HV164_RS19570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV164_RS19615	COG2003	Belongs to the UPF0758 family
HV164_RS19635	COG2378	regulation of single-species biofilm formation
HV164_RS19640	COG3596	GTP binding
HV164_RS19675	COG1403	HNH endonuclease
HV164_RS19720	COG0582	viral genome integration into host DNA
HV164_RS19740	COG1064	alcohol dehydrogenase
HV164_RS19745	COG3265	gluconokinase activity
HV164_RS19750	COG1063	alcohol dehydrogenase
HV164_RS19755	COG1028	Short-chain dehydrogenase reductase Sdr
HV164_RS19760	COG2610	gluconate transmembrane transporter activity
HV164_RS19765	COG1609	Transcriptional regulator
HV164_RS19770	COG0433	COG0433 Predicted ATPase
HV164_RS19775	COG0795	lipopolysaccharide-transporting ATPase activity
HV164_RS19780	COG0795	lipopolysaccharide-transporting ATPase activity
HV164_RS19790	COG2927	DNA polymerase III (CHI subunit)
HV164_RS19795	COG0525	valine-tRNA ligase activity
HV164_RS19825	COG2731	YhcH YjgK YiaL family protein
HV164_RS19860	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HV164_RS19875	COG1263	PTS System
HV164_RS19875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV164_RS19880	COG0366	Alpha amylase catalytic
HV164_RS19895	COG2026	Addiction module toxin, RelE StbE family
HV164_RS19900	COG3077	Addiction module antitoxin, RelB DinJ family
HV164_RS19905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV164_RS19905	COG3711	transcriptional antiterminator
HV164_RS19920	COG3964	amidohydrolase
HV164_RS19955	COG0312	modulator of DNA gyrase
HV164_RS19975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HV164_RS19990	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV164_RS19995	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV164_RS20000	COG1129	ABC transporter
HV164_RS20005	COG1879	ABC-type sugar transport system periplasmic component
HV164_RS20015	COG3391	amine dehydrogenase activity
HV164_RS20020	COG4771	TonB-dependent receptor
HV164_RS20025	COG2105	PFAM AIG2 family protein
HV164_RS20030	COG2911	Protein conserved in bacteria
HV164_RS20035	COG0729	surface antigen
HV164_RS20045	COG1609	Transcriptional regulator
HV164_RS20050	COG0673	inositol 2-dehydrogenase activity
HV164_RS20055	COG0673	inositol 2-dehydrogenase activity
HV164_RS20070	COG2211	Major facilitator Superfamily
HV164_RS20080	COG1253	flavin adenine dinucleotide binding
HV164_RS20090	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HV164_RS20095	COG1218	3'(2'),5'-bisphosphate nucleotidase
HV164_RS20105	COG1733	regulation of RNA biosynthetic process
HV164_RS20110	COG0702	epimerase
HV164_RS20120	COG0697	spore germination
HV164_RS20125	COG0840	transmembrane signaling receptor activity
HV164_RS20135	COG1113	amino acid transport
HV164_RS20140	COG0545	Peptidyl-prolyl cis-trans isomerase
HV164_RS20145	COG3061	Opacity-associated protein A
HV164_RS20160	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HV164_RS20165	COG2965	DNA replication, synthesis of RNA primer
HV164_RS20175	COG0730	response to heat
HV164_RS20230	COG1073	alpha beta
HV164_RS20235	COG3650	response to hydrogen peroxide
HV164_RS20245	COG1960	acyl-CoA dehydrogenase activity
HV164_RS20250	COG0754	glutathionylspermidine amidase activity
HV164_RS20255	COG5463	Belongs to the UPF0441 family
HV164_RS20260	COG3766	membrane
HV164_RS20270	COG1842	Phage shock protein A
HV164_RS20275	COG3789	protein conserved in bacteria
HV164_RS20280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV164_RS20285	COG0557	exoribonuclease II activity
HV164_RS20300	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HV164_RS20305	COG0330	HflC and HflK could
HV164_RS20310	COG0330	HflC and HflK could
HV164_RS20315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HV164_RS20320	COG1923	regulation of RNA biosynthetic process
HV164_RS20335	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV164_RS20340	COG0802	atpase or kinase
HV164_RS20345	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HV164_RS20345	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HV164_RS20350	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HV164_RS20385	COG1511	domain protein
HV164_RS20385	COG3264	Mechanosensitive ion channel
HV164_RS20400	COG1053	succinate dehydrogenase
HV164_RS20405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV164_RS20450	COG1509	lysine 2,3-aminomutase activity
HV164_RS20475	COG0531	amino acid
HV164_RS20480	COG3030	protein affecting phage T7 exclusion by the F plasmid
HV164_RS20485	COG1027	Aspartate ammonia-lyase
HV164_RS20490	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV164_RS20505	COG1309	transcriptional regulator
HV164_RS20550	COG3290	protein histidine kinase activity
HV164_RS20555	COG4565	transcriptional regulatory protein
HV164_RS20560	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV164_RS20565	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV164_RS20565	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV164_RS20570	COG3647	Membrane
HV164_RS20575	COG2211	Major facilitator Superfamily
HV164_RS20580	COG1486	melibiose metabolic process
HV164_RS20585	COG2169	Transcriptional regulator
HV164_RS20590	COG1982	Orn Lys Arg decarboxylase major
HV164_RS20595	COG2207	Transcriptional regulator
HV164_RS20600	COG0531	amino acid
HV164_RS20610	COG0745	RESPONSE REGULATOR receiver
HV164_RS20640	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HV164_RS20645	COG2824	Alkylphosphonate utilization operon protein PhnA
HV164_RS20650	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HV164_RS20655	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HV164_RS20660	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HV164_RS20665	COG3639	organic phosphonate transmembrane transporter activity
HV164_RS20670	COG2188	Transcriptional regulator
HV164_RS20675	COG3624	Phosphonate C-P lyase system protein PhnG
HV164_RS20680	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HV164_RS20685	COG3626	phosphonate metabolism
HV164_RS20690	COG3627	carbon phosphorus lyase activity
HV164_RS20695	COG4107	phosphonate C-P lyase system protein PhnK
HV164_RS20700	COG4778	phosphonate C-P lyase system protein PhnL
HV164_RS20705	COG3454	Phosphonate metabolism
HV164_RS20710	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HV164_RS20715	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HV164_RS20740	COG1129	ABC transporter
HV164_RS20745	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV164_RS20805	COG0745	RESPONSE REGULATOR receiver
HV164_RS20815	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HV164_RS20820	COG1301	dicarboxylic acid transport
HV164_RS20825	COG4235	cytochrome complex assembly
HV164_RS20830	COG3088	subunit of a heme lyase
HV164_RS20835	COG1138	Cytochrome C-type biogenesis protein
HV164_RS20840	COG3301	Polysulphide reductase, NrfD
HV164_RS20845	COG0437	4 iron, 4 sulfur cluster binding
HV164_RS20850	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HV164_RS20865	COG3162	membrane
HV164_RS20880	COG0673	inositol 2-dehydrogenase activity
HV164_RS20885	COG1346	cytolysis
HV164_RS20890	COG1380	Effector of murein hydrolase LrgA
HV164_RS20895	COG0583	DNA-binding transcription factor activity
HV164_RS20900	COG0025	NhaP-type Na H and K H
HV164_RS20905	COG2252	PERMEase
HV164_RS20910	COG0789	Transcriptional regulator
HV164_RS20920	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV164_RS20935	COG0629	single-stranded DNA binding
HV164_RS20940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HV164_RS20945	COG2315	Protein conserved in bacteria
HV164_RS20950	COG3700	Belongs to the class B bacterial acid phosphatase family
HV164_RS20955	COG1448	Aminotransferase
HV164_RS20965	COG0305	Participates in initiation and elongation during chromosome replication
HV164_RS20980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV164_RS20990	COG0735	belongs to the Fur family
HV164_RS20995	COG3237	CsbD-like
HV164_RS21000	COG0534	Mate efflux family protein
HV164_RS21010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HV164_RS21045	COG2182	Extracellular solute-binding protein
HV164_RS21055	COG3833	ABC-type maltose transport systems, permease component
HV164_RS21060	COG0477	Major facilitator Superfamily
HV164_RS21060	COG2814	Major facilitator Superfamily
HV164_RS21065	COG3223	Belongs to the PsiE family
HV164_RS21070	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV164_RS21095	COG0527	aspartate kinase activity
HV164_RS21100	COG3541	Predicted nucleotidyltransferase
HV164_RS21110	COG4650	regulator
HV164_RS21120	COG1187	pseudouridine synthase activity
HV164_RS21135	COG3657	addiction module killer protein
HV164_RS21140	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HV164_RS21165	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HV164_RS21175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HV164_RS21210	COG0151	Belongs to the GarS family
HV164_RS21215	COG2204	response regulator
HV164_RS21275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV164_RS21280	COG2104	thiamine diphosphate biosynthetic process
HV164_RS21295	COG1278	Cold shock
HV164_RS21305	COG0085	RNA polymerase activity
HV164_RS21310	COG0222	ribosome binding
HV164_RS21315	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HV164_RS21330	COG0250	Participates in transcription elongation, termination and antitermination
HV164_RS21340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HV164_RS21375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HV164_RS21435	COG0583	DNA-binding transcription factor activity
HV164_RS21450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HV164_RS21470	COG2207	Transcriptional regulator
HV164_RS21480	COG0371	Dehydrogenase
HV164_RS21500	COG0527	aspartate kinase activity
HV164_RS21500	COG0460	homoserine dehydrogenase
HV164_RS21505	COG0626	cystathionine gamma-synthase activity
HV164_RS21515	COG2211	Major facilitator Superfamily
HV164_RS21525	COG0254	rRNA binding
HV164_RS21530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HV164_RS21535	COG1609	Transcriptional regulator
HV164_RS21540	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV164_RS21550	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HV164_RS21555	COG1575	Belongs to the MenA family. Type 1 subfamily
HV164_RS21575	COG3074	FtsZ-dependent cytokinesis
HV164_RS21580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HV164_RS21590	COG1494	fructose-1,6-bisphosphatase
HV164_RS21600	COG3152	Membrane
HV164_RS21615	COG0471	metal ion transport
HV164_RS21655	COG3678	ATP-independent chaperone mediated protein folding
HV164_RS21660	COG0745	RESPONSE REGULATOR receiver
HV164_RS21665	COG2205	protein histidine kinase activity
HV164_RS21670	COG2258	MOSC domain
HV164_RS21675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV164_RS21720	COG1454	alcohol dehydrogenase
HV164_RS21735	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HV164_RS21770	COG0437	4 iron, 4 sulfur cluster binding
HV164_RS21775	COG2864	formate dehydrogenase
HV164_RS21785	COG0456	acetyltransferase
HV164_RS21790	COG1490	D-aminoacyl-tRNA deacylase activity
HV164_RS21800	COG1011	Hydrolase
HV164_RS21810	COG0477	Major facilitator Superfamily
HV164_RS21820	COG1063	alcohol dehydrogenase
HV164_RS21825	COG3684	Belongs to the aldolase LacD family
HV164_RS21830	COG2084	Dehydrogenase
HV164_RS21835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV164_RS21840	COG1349	DNA-binding transcription factor activity
HV164_RS21845	COG2271	Major facilitator Superfamily
HV164_RS21850	COG1082	Xylose isomerase domain protein TIM barrel
HV164_RS21855	COG2188	Transcriptional regulator
HV164_RS21870	COG3852	Histidine kinase
HV164_RS21885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV164_RS21910	COG0204	Acyl-transferase
HV164_RS21925	COG3084	Protein conserved in bacteria
HV164_RS21930	COG0746	molybdenum cofactor guanylyltransferase activity
HV164_RS21935	COG1763	Mo-molybdopterin cofactor biosynthetic process
HV164_RS21975	COG1739	Uncharacterized protein family UPF0029
HV164_RS22000	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV164_RS22015	COG0805	protein transport
HV164_RS22035	COG3165	ubiquinone biosynthetic process from chorismate
HV164_RS22060	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HV164_RS22065	COG0583	DNA-binding transcription factor activity
HV164_RS22070	COG0697	spore germination
HV164_RS22075	COG0561	phosphatase activity
HV164_RS22080	COG2267	carboxylic ester hydrolase activity
HV164_RS22085	COG1280	lysine exporter protein (LysE YggA)
HV164_RS22090	COG1280	lysine exporter protein (LysE YggA)
HV164_RS22100	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HV164_RS22110	COG2962	Rard protein
HV164_RS22115	COG0598	Magnesium transport protein CorA
HV164_RS22125	COG1011	Hydrolase
HV164_RS22145	COG5567	small periplasmic lipoprotein
HV164_RS22170	COG2959	enzyme of heme biosynthesis
HV164_RS22175	COG3071	HemY protein
HV164_RS22220	COG2244	polysaccharide biosynthetic process
HV164_RS22225	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HV164_RS22230	COG0456	acetyltransferase
HV164_RS22235	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HV164_RS22240	COG1088	dTDP-glucose 4,6-dehydratase activity
HV164_RS22245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HV164_RS22250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HV164_RS22260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HV164_RS22265	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HV164_RS22275	COG3118	belongs to the thioredoxin family
HV164_RS22310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV164_RS22325	COG3978	acetolactate synthase activity
HV164_RS22345	COG3085	chromosome segregation
HV164_RS22385	COG2186	Transcriptional regulator
HV164_RS22390	COG0477	Major facilitator Superfamily
HV164_RS22395	COG1609	Transcriptional regulator
HV164_RS22400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV164_RS22410	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV164_RS22415	COG1129	ABC transporter
HV164_RS22420	COG1869	D-ribose catabolic process
HV164_RS22445	COG1522	sequence-specific DNA binding
HV164_RS22450	COG0716	FMN binding
HV164_RS22465	COG3312	ion transport
HV164_RS22490	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HV164_RS22495	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HV164_RS22505	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HV164_RS22525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HV164_RS22530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HV164_RS22535	COG0573	inorganic phosphate transmembrane transporter activity
HV164_RS22540	COG0581	inorganic phosphate transmembrane transporter activity
HV164_RS22550	COG0704	Plays a role in the regulation of phosphate uptake
HV164_RS22555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV164_RS22560	COG2252	PERMEase
HV164_RS22565	COG0431	NADPH-dependent FMN reductase
HV164_RS22570	COG2091	lysine biosynthetic process via aminoadipic acid
HV164_RS22605	COG0230	Belongs to the bacterial ribosomal protein bL34 family