locus-tag	class	description
WM46_RS00105	COG0582	viral genome integration into host DNA
WM46_RS00115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM46_RS00140	COG2867	negative regulation of translational initiation
WM46_RS00150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WM46_RS00155	COG0497	DNA recombination
WM46_RS00170	COG4536	flavin adenine dinucleotide binding
WM46_RS00175	COG4137	Cytochrome C assembly protein
WM46_RS00180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WM46_RS00215	COG2885	chlorophyll binding
WM46_RS00220	COG2199	diguanylate cyclase activity
WM46_RS00235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WM46_RS00240	COG1605	Chorismate mutase
WM46_RS00240	COG0287	Prephenate dehydrogenase
WM46_RS00245	COG1605	Chorismate mutase
WM46_RS00245	COG0077	Prephenate dehydratase
WM46_RS00255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WM46_RS00260	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WM46_RS00280	COG0542	response to heat
WM46_RS00305	COG0477	Major facilitator Superfamily
WM46_RS00310	COG5544	Lipoprotein
WM46_RS00315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WM46_RS00320	COG0045	succinate-CoA ligase (ADP-forming) activity
WM46_RS00320	COG1042	CoA-binding domain protein
WM46_RS00320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WM46_RS00325	COG3148	PFAM DTW domain containing protein
WM46_RS00330	COG3118	belongs to the thioredoxin family
WM46_RS00340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WM46_RS00355	COG0513	Belongs to the DEAD box helicase family
WM46_RS00365	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WM46_RS00380	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
WM46_RS00385	COG3026	antisigma factor binding
WM46_RS00390	COG3086	response to oxidative stress
WM46_RS00400	COG0681	Belongs to the peptidase S26 family
WM46_RS00415	COG1381	Involved in DNA repair and RecF pathway recombination
WM46_RS00420	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WM46_RS00430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM46_RS00435	COG1737	Transcriptional regulator
WM46_RS00440	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
WM46_RS00445	COG1263	PTS System
WM46_RS00445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS00450	COG0560	Phosphoserine phosphatase
WM46_RS00470	COG0737	Belongs to the 5'-nucleotidase family
WM46_RS00480	COG2205	protein histidine kinase activity
WM46_RS00485	COG3170	Tfp pilus assembly protein FimV
WM46_RS00490	COG2204	response regulator
WM46_RS00495	COG0347	Belongs to the P(II) protein family
WM46_RS00500	COG1017	nitric oxide dioxygenase activity
WM46_RS00500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WM46_RS00515	COG2259	Doxx family
WM46_RS00520	COG1940	carbohydrate kinase activity
WM46_RS00525	COG0457	Tetratricopeptide repeat
WM46_RS00530	COG0477	Major facilitator Superfamily
WM46_RS00530	COG2814	Major facilitator Superfamily
WM46_RS00540	COG2814	Major facilitator Superfamily
WM46_RS00545	COG3711	transcriptional antiterminator
WM46_RS00550	COG0517	IMP dehydrogenase activity
WM46_RS00550	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WM46_RS00555	COG1069	ribulokinase activity
WM46_RS00565	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM46_RS00570	COG1129	ABC transporter
WM46_RS00580	COG3683	transport system, periplasmic component
WM46_RS00585	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
WM46_RS00625	COG0822	iron-sulfur transferase activity
WM46_RS00645	COG0633	Ferredoxin
WM46_RS00650	COG2975	iron-sulfur cluster assembly
WM46_RS00670	COG2897	thiosulfate sulfurtransferase activity
WM46_RS00675	COG2373	Large extracellular alpha-helical protein
WM46_RS00680	COG4953	penicillin-binding protein 1C
WM46_RS00715	COG2976	Protein conserved in bacteria
WM46_RS00730	COG1645	bacterial-type flagellum-dependent swarming motility
WM46_RS00740	COG0517	IMP dehydrogenase activity
WM46_RS00740	COG0516	GMP reductase activity
WM46_RS00755	COG2200	EAL domain
WM46_RS00760	COG0248	Ppx GppA phosphatase
WM46_RS00765	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WM46_RS00770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WM46_RS00780	COG2723	6-phospho-beta-galactosidase activity
WM46_RS00790	COG2233	PERMEase
WM46_RS00805	COG1446	asparaginase
WM46_RS00820	COG1393	Belongs to the ArsC family
WM46_RS00825	COG4783	chaperone-mediated protein folding
WM46_RS00835	COG0628	permease
WM46_RS00840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WM46_RS00845	COG2716	regulation of RNA biosynthetic process
WM46_RS00855	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WM46_RS00865	COG2321	neutral zinc metallopeptidase
WM46_RS00875	COG0400	carboxylic ester hydrolase activity
WM46_RS00890	COG1393	Belongs to the ArsC family
WM46_RS00900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WM46_RS00905	COG3850	Histidine kinase
WM46_RS00915	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM46_RS00915	COG0493	'glutamate synthase
WM46_RS00925	COG5342	invasion associated locus B
WM46_RS00930	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WM46_RS00965	COG4812	Cobalamin adenosyltransferase
WM46_RS01040	COG0860	N-Acetylmuramoyl-L-alanine amidase
WM46_RS01060	COG2837	iron assimilation
WM46_RS01065	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS01075	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WM46_RS01080	COG4208	sulfate ABC transporter
WM46_RS01085	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WM46_RS01090	COG0737	Belongs to the 5'-nucleotidase family
WM46_RS01130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS01160	COG3530	Putative quorum-sensing-regulated virulence factor
WM46_RS01165	COG0385	Bile acid
WM46_RS01170	COG0583	DNA-binding transcription factor activity
WM46_RS01180	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
WM46_RS01185	COG2211	Major facilitator Superfamily
WM46_RS01190	COG0583	DNA-binding transcription factor activity
WM46_RS01240	COG3415	Transposase
WM46_RS01245	COG3415	Transposase
WM46_RS01260	COG2199	diguanylate cyclase activity
WM46_RS01260	COG2200	EAL domain
WM46_RS01265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WM46_RS01285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WM46_RS01290	COG1263	PTS System
WM46_RS01290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS01300	COG0667	Aldo Keto reductase
WM46_RS01305	COG3961	Belongs to the TPP enzyme family
WM46_RS01325	COG3122	Protein conserved in bacteria
WM46_RS01340	COG3279	Response regulator of the LytR AlgR family
WM46_RS01345	COG3275	phosphorelay sensor kinase activity
WM46_RS01350	COG0436	Aminotransferase
WM46_RS01360	COG1560	Kdo2-lipid A biosynthetic process
WM46_RS01370	COG2807	transmembrane transport
WM46_RS01375	COG0590	tRNA wobble adenosine to inosine editing
WM46_RS01385	COG0288	reversible hydration of carbon dioxide
WM46_RS01390	COG0583	DNA-binding transcription factor activity
WM46_RS01400	COG0765	amino acid transport
WM46_RS01405	COG1126	abc transporter atp-binding protein
WM46_RS01420	COG0412	Dienelactone hydrolase
WM46_RS01455	COG2116	formate transmembrane transporter activity
WM46_RS01465	COG2067	long-chain fatty acid transport protein
WM46_RS01475	COG3691	Protein conserved in bacteria
WM46_RS01490	COG2062	phosphohistidine phosphatase, SixA
WM46_RS01515	COG0730	response to heat
WM46_RS01520	COG3101	peptidyl-lysine hydroxylation
WM46_RS01535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WM46_RS01565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WM46_RS01575	COG0586	Pfam SNARE associated Golgi protein
WM46_RS01585	COG0285	dihydrofolate synthase activity
WM46_RS01590	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
WM46_RS01595	COG1286	toxin biosynthetic process
WM46_RS01600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WM46_RS01605	COG0163	prenyltransferase activity
WM46_RS01620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM46_RS01635	COG4598	ABC transporter
WM46_RS01640	COG5464	transposase or invertase
WM46_RS01645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WM46_RS01650	COG1090	epimerase
WM46_RS01655	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WM46_RS01660	COG0625	glutathione transferase activity
WM46_RS01665	COG0625	glutathione transferase activity
WM46_RS01670	COG0622	Phosphoesterase
WM46_RS01680	COG1609	Transcriptional regulator
WM46_RS01685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS01695	COG3037	sugar-specific permease SgaT UlaA
WM46_RS01700	COG3959	Transketolase, thiamine diphosphate binding domain
WM46_RS01705	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WM46_RS01710	COG1288	antiporter activity
WM46_RS01735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WM46_RS01740	COG0490	domain, Protein
WM46_RS01740	COG0471	metal ion transport
WM46_RS01750	COG0436	Aminotransferase
WM46_RS01755	COG0583	DNA-binding transcription factor activity
WM46_RS01775	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WM46_RS01790	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WM46_RS01800	COG0839	Belongs to the complex I subunit 6 family
WM46_RS01810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WM46_RS01815	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WM46_RS01825	COG0835	chemotaxis
WM46_RS01825	COG0784	Response regulator, receiver
WM46_RS01835	COG2153	protein acetylation
WM46_RS01840	COG4575	ribosome binding
WM46_RS01845	COG1169	isochorismate synthase
WM46_RS01870	COG0318	PFAM AMP-dependent synthetase and ligase
WM46_RS01935	COG1414	Transcriptional regulator
WM46_RS01945	COG2271	Major facilitator Superfamily
WM46_RS01955	COG5464	transposase or invertase
WM46_RS01960	COG0247	lactate metabolic process
WM46_RS01970	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WM46_RS01975	COG2271	Major facilitator Superfamily
WM46_RS01980	COG0584	glycerophosphoryl diester phosphodiesterase
WM46_RS01985	COG3642	lipopolysaccharide core region biosynthetic process
WM46_RS01990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WM46_RS02000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WM46_RS02015	COG3730	PTS system glucitol sorbitol-specific
WM46_RS02025	COG3732	PTS system glucitol sorbitol-specific
WM46_RS02030	COG0673	inositol 2-dehydrogenase activity
WM46_RS02040	COG0183	Belongs to the thiolase family
WM46_RS02045	COG2031	fatty acid transporter
WM46_RS02050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WM46_RS02055	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
WM46_RS02060	COG2204	response regulator
WM46_RS02065	COG3852	Histidine kinase
WM46_RS02075	COG2197	response regulator
WM46_RS02080	COG2198	Histidine kinase
WM46_RS02080	COG0642	Histidine kinase
WM46_RS02090	COG1477	protein flavinylation
WM46_RS02095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WM46_RS02095	COG2169	Transcriptional regulator
WM46_RS02100	COG3145	DNA-N1-methyladenine dioxygenase activity
WM46_RS02105	COG4615	Cyclic peptide transporter
WM46_RS02110	COG2239	Acts as a magnesium transporter
WM46_RS02115	COG0659	secondary active sulfate transmembrane transporter activity
WM46_RS02130	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM46_RS02130	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM46_RS02135	COG3062	negative regulation of establishment of protein localization
WM46_RS02145	COG0437	4 iron, 4 sulfur cluster binding
WM46_RS02150	COG0348	domain, Protein
WM46_RS02155	COG3043	anaerobic respiration
WM46_RS02160	COG3005	denitrification pathway
WM46_RS02165	COG4133	protoheme IX ABC transporter activity
WM46_RS02170	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WM46_RS02175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WM46_RS02180	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WM46_RS02190	COG1138	Cytochrome C-type biogenesis protein
WM46_RS02195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WM46_RS02200	COG3088	subunit of a heme lyase
WM46_RS02200	COG4235	cytochrome complex assembly
WM46_RS02205	COG2197	response regulator
WM46_RS02220	COG2246	polysaccharide biosynthetic process
WM46_RS02230	COG3083	sulfuric ester hydrolase activity
WM46_RS02250	COG1061	Type III restriction enzyme res subunit
WM46_RS02260	COG1187	pseudouridine synthase activity
WM46_RS02265	COG2814	Major facilitator Superfamily
WM46_RS02280	COG4172	Belongs to the ABC transporter superfamily
WM46_RS02285	COG4239	(ABC) transporter, permease
WM46_RS02290	COG4174	ABC transporter (Permease)
WM46_RS02295	COG4166	transmembrane transport
WM46_RS02300	COG2200	EAL domain
WM46_RS02305	COG0791	NLP P60 protein
WM46_RS02315	COG0671	phosphoesterase, PA-phosphatase related
WM46_RS02320	COG0523	cobalamin synthesis protein
WM46_RS02325	COG0246	Mannitol dehydrogenase
WM46_RS02330	COG1312	Catalyzes the dehydration of D-mannonate
WM46_RS02335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WM46_RS02340	COG3005	denitrification pathway
WM46_RS02350	COG3381	protein complex oligomerization
WM46_RS02375	COG1105	Belongs to the carbohydrate kinase PfkB family
WM46_RS02380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM46_RS02380	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
WM46_RS02380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM46_RS02385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM46_RS02390	COG2313	pseudouridylate synthase activity
WM46_RS02395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WM46_RS02400	COG1522	sequence-specific DNA binding
WM46_RS02400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM46_RS02410	COG2855	membrane
WM46_RS02415	COG0583	DNA-binding transcription factor activity
WM46_RS02420	COG0833	amino acid
WM46_RS02425	COG4771	TonB-dependent receptor
WM46_RS02445	COG2311	Membrane
WM46_RS02460	COG1879	ABC-type sugar transport system periplasmic component
WM46_RS02465	COG1129	ABC transporter
WM46_RS02480	COG2949	membrane
WM46_RS02490	COG1346	cytolysis
WM46_RS02505	COG2271	Major facilitator Superfamily
WM46_RS02520	COG0625	glutathione transferase activity
WM46_RS02525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WM46_RS02530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WM46_RS02535	COG1538	Outer membrane efflux protein
WM46_RS02540	COG0586	Pfam SNARE associated Golgi protein
WM46_RS02555	COG1686	Belongs to the peptidase S11 family
WM46_RS02565	COG0277	FAD linked oxidase domain protein
WM46_RS02570	COG1472	Belongs to the glycosyl hydrolase 3 family
WM46_RS02575	COG1732	Glycine betaine
WM46_RS02580	COG1174	glycine betaine transport
WM46_RS02585	COG1125	glycine betaine transport
WM46_RS02590	COG1174	glycine betaine transport
WM46_RS02600	COG0789	Transcriptional regulator
WM46_RS02605	COG3275	phosphorelay sensor kinase activity
WM46_RS02615	COG4807	Protein conserved in bacteria
WM46_RS02620	COG4808	Protein conserved in bacteria
WM46_RS02645	COG3121	Chaperone
WM46_RS02655	COG3539	Fimbrial protein
WM46_RS02660	COG5455	response to cobalt ion
WM46_RS02680	COG0351	phosphomethylpyrimidine kinase
WM46_RS02685	COG2188	Transcriptional regulator
WM46_RS02690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM46_RS02695	COG1397	ADP-ribosylglycohydrolase
WM46_RS02700	COG2211	Major facilitator Superfamily
WM46_RS02715	COG0826	peptidase U32
WM46_RS02720	COG0745	RESPONSE REGULATOR receiver
WM46_RS02725	COG2205	protein histidine kinase activity
WM46_RS02750	COG0443	Heat shock 70 kDa protein
WM46_RS02755	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
WM46_RS02760	COG5002	protein histidine kinase activity
WM46_RS02760	COG5001	Diguanylate cyclase
WM46_RS02760	COG3447	MASE1 domain protein
WM46_RS02775	COG2982	Protein involved in outer membrane biogenesis
WM46_RS02780	COG1253	flavin adenine dinucleotide binding
WM46_RS02810	COG0463	Glycosyl transferase, family 2
WM46_RS02815	COG1045	serine acetyltransferase
WM46_RS02820	COG0438	transferase activity, transferring glycosyl groups
WM46_RS02830	COG1216	Glycosyl transferase, family 2
WM46_RS02835	COG0110	maltose O-acetyltransferase activity
WM46_RS02840	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
WM46_RS02845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WM46_RS02850	COG1051	belongs to the nudix hydrolase family
WM46_RS02855	COG0297	glycogen (starch) synthase activity
WM46_RS02865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WM46_RS02870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WM46_RS02875	COG2244	polysaccharide biosynthetic process
WM46_RS02880	COG2327	Polysaccharide pyruvyl transferase
WM46_RS02895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WM46_RS02900	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WM46_RS02920	COG0483	inositol monophosphate 1-phosphatase activity
WM46_RS02955	COG0110	maltose O-acetyltransferase activity
WM46_RS02985	COG0562	UDP-galactopyranose mutase
WM46_RS02995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
WM46_RS03020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WM46_RS03050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WM46_RS03055	COG0583	DNA-binding transcription factor activity
WM46_RS03065	COG0531	amino acid
WM46_RS03070	COG2391	methyltransferase activity
WM46_RS03075	COG0425	Belongs to the sulfur carrier protein TusA family
WM46_RS03080	COG2925	Exonuclease
WM46_RS03085	COG0582	viral genome integration into host DNA
WM46_RS03170	COG3547	Transposase (IS116 IS110 IS902 family)
WM46_RS03185	COG1484	DNA-dependent DNA replication
WM46_RS03190	COG0305	Participates in initiation and elongation during chromosome replication
WM46_RS03195	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
WM46_RS03200	COG0484	heat shock protein binding
WM46_RS03220	COG3772	lysozyme
WM46_RS03320	COG4386	tail sheath protein
WM46_RS03395	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WM46_RS03410	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
WM46_RS03415	COG1289	transmembrane transporter activity
WM46_RS03430	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WM46_RS03450	COG4656	Part of a membrane complex involved in electron transport
WM46_RS03455	COG1454	alcohol dehydrogenase
WM46_RS03455	COG1012	belongs to the aldehyde dehydrogenase family
WM46_RS03470	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
WM46_RS03485	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
WM46_RS03645	COG1376	ErfK ybiS ycfS ynhG family protein
WM46_RS03655	COG0534	Mate efflux family protein
WM46_RS03665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WM46_RS03670	COG0477	Major facilitator Superfamily
WM46_RS03685	COG0583	DNA-binding transcription factor activity
WM46_RS03705	COG3468	outer membrane autotransporter barrel domain protein
WM46_RS03710	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WM46_RS03720	COG1418	mRNA catabolic process
WM46_RS03725	COG0270	DNA (cytosine-5-)-methyltransferase activity
WM46_RS03730	COG3727	T/G mismatch-specific endonuclease activity
WM46_RS03735	COG0697	spore germination
WM46_RS03740	COG2354	Protein conserved in bacteria
WM46_RS03745	COG5475	Uncharacterized small protein (DUF2158)
WM46_RS03770	COG2197	response regulator
WM46_RS03780	COG1987	bacterial-type flagellum assembly
WM46_RS03805	COG1580	Controls the rotational direction of flagella during chemotaxis
WM46_RS03815	COG2882	bacterial-type flagellum organization
WM46_RS03820	COG1157	protein secretion by the type III secretion system
WM46_RS03830	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WM46_RS03845	COG0425	Belongs to the sulfur carrier protein TusA family
WM46_RS03860	COG0366	Alpha amylase catalytic
WM46_RS03895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM46_RS03905	COG0765	amino acid transport
WM46_RS03910	COG1126	abc transporter atp-binding protein
WM46_RS03915	COG2197	response regulator
WM46_RS03930	COG2197	response regulator
WM46_RS03965	COG0732	type I restriction modification DNA specificity domain
WM46_RS03970	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WM46_RS04005	COG1280	lysine exporter protein (LysE YggA)
WM46_RS04015	COG3318	Belongs to the UPF0149 family
WM46_RS04015	COG3012	SEC-C Motif Domain Protein
WM46_RS04020	COG0814	amino acid
WM46_RS04030	COG1528	Iron-storage protein
WM46_RS04045	COG0477	Major facilitator Superfamily
WM46_RS04060	COG1528	Iron-storage protein
WM46_RS04075	COG1879	ABC-type sugar transport system periplasmic component
WM46_RS04080	COG1129	ABC transporter
WM46_RS04085	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM46_RS04135	COG1301	dicarboxylic acid transport
WM46_RS04170	COG0840	transmembrane signaling receptor activity
WM46_RS04185	COG0745	RESPONSE REGULATOR receiver
WM46_RS04195	COG3539	Fimbrial protein
WM46_RS04200	COG3188	usher protein
WM46_RS04205	COG3121	Chaperone
WM46_RS04235	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
WM46_RS04245	COG3102	Protein conserved in bacteria
WM46_RS04265	COG3788	relative of glutathione S-transferase, MAPEG superfamily
WM46_RS04270	COG1801	Protein of unknown function DUF72
WM46_RS04275	COG1335	isochorismatase
WM46_RS04285	COG0494	nUDIX hydrolase
WM46_RS04290	COG0217	transcriptional regulatory protein
WM46_RS04310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WM46_RS04320	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
WM46_RS04325	COG0739	heme binding
WM46_RS04330	COG1560	Kdo2-lipid A biosynthetic process
WM46_RS04340	COG1737	Transcriptional regulator
WM46_RS04345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WM46_RS04350	COG0129	dihydroxy-acid dehydratase activity
WM46_RS04355	COG0800	Aldolase
WM46_RS04365	COG3141	response to X-ray
WM46_RS04375	COG2979	Protein of unknown function (DUF533)
WM46_RS04380	COG1770	oligopeptidase
WM46_RS04385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WM46_RS04390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WM46_RS04400	COG2372	response to copper ion
WM46_RS04405	COG1276	copper resistance
WM46_RS04485	COG3723	Recombinational DNA repair protein, rece pathway
WM46_RS04555	COG3646	Phage regulatory protein
WM46_RS04555	COG3645	SOS response
WM46_RS04560	COG1846	Transcriptional regulator
WM46_RS04625	COG0484	heat shock protein binding
WM46_RS04635	COG3772	lysozyme
WM46_RS04780	COG3107	peptidoglycan biosynthetic process
WM46_RS04780	COG1674	ftsk spoiiie
WM46_RS04820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WM46_RS04840	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WM46_RS04860	COG3008	intermembrane lipid transfer
WM46_RS04865	COG2995	paraquat-inducible protein a
WM46_RS04870	COG1956	GAF domain-containing protein
WM46_RS04890	COG2814	Major facilitator Superfamily
WM46_RS04895	COG1414	Transcriptional regulator
WM46_RS04925	COG0768	penicillin binding
WM46_RS04930	COG2226	methyltransferase
WM46_RS04950	COG3716	PTS system mannose fructose sorbose family IID component
WM46_RS04955	COG3715	PTS system
WM46_RS04960	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS04960	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS04975	COG2200	EAL domain
WM46_RS04980	COG1760	l-serine dehydratase
WM46_RS05000	COG0251	oxidation-reduction process
WM46_RS05005	COG1199	ATP-dependent helicase activity
WM46_RS05010	COG1214	PFAM Peptidase M22, glycoprotease
WM46_RS05015	COG3065	identical protein binding
WM46_RS05020	COG0318	PFAM AMP-dependent synthetase and ligase
WM46_RS05025	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
WM46_RS05030	COG0473	3-isopropylmalate dehydrogenase activity
WM46_RS05035	COG0583	DNA-binding transcription factor activity
WM46_RS05050	COG3615	Tellurite resistance protein tehB
WM46_RS05065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WM46_RS05075	COG0251	oxidation-reduction process
WM46_RS05110	COG3443	Belongs to the bacterial solute-binding protein 9 family
WM46_RS05125	COG2894	cell division
WM46_RS05140	COG0179	Fumarylacetoacetate (FAA) hydrolase
WM46_RS05170	COG2719	SpoVR family
WM46_RS05180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WM46_RS05190	COG1619	proteins homologs of microcin C7 resistance protein MccF
WM46_RS05200	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
WM46_RS05210	COG4774	siderophore transport
WM46_RS05220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WM46_RS05220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS05220	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
WM46_RS05225	COG1461	Dihydroxyacetone kinase
WM46_RS05230	COG2376	Dihydroxyacetone kinase
WM46_RS05250	COG0217	transcriptional regulatory protein
WM46_RS05255	COG1280	lysine exporter protein (LysE YggA)
WM46_RS05260	COG2826	transposase and inactivated derivatives, IS30 family
WM46_RS05295	COG2200	EAL domain
WM46_RS05300	COG0789	Transcriptional regulator
WM46_RS05315	COG4977	sequence-specific DNA binding
WM46_RS05320	COG2226	methyltransferase
WM46_RS05325	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WM46_RS05330	COG1757	Na H antiporter
WM46_RS05335	COG2169	Transcriptional regulator
WM46_RS05385	COG1396	sequence-specific DNA binding
WM46_RS05400	COG2003	Belongs to the UPF0758 family
WM46_RS05405	COG4974	Belongs to the 'phage' integrase family
WM46_RS05435	COG0561	phosphatase activity
WM46_RS05440	COG0738	Major facilitator superfamily
WM46_RS05465	COG0582	viral genome integration into host DNA
WM46_RS05470	COG0012	GTP binding
WM46_RS05490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WM46_RS05490	COG2857	Cytochrome c1
WM46_RS05505	COG1120	ATPase activity
WM46_RS05510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM46_RS05515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WM46_RS05525	COG0659	secondary active sulfate transmembrane transporter activity
WM46_RS05560	COG2890	protein-(glutamine-N5) methyltransferase activity
WM46_RS05580	COG0387	Pfam Sodium calcium exchanger
WM46_RS05585	COG4572	Cation transport regulator
WM46_RS05590	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
WM46_RS05600	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
WM46_RS05605	COG4932	domain protein
WM46_RS05610	COG2197	response regulator
WM46_RS05615	COG3850	Histidine kinase
WM46_RS05625	COG2223	nitrite transmembrane transporter activity
WM46_RS05635	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
WM46_RS05640	COG1140	nitrate reductase beta subunit
WM46_RS05645	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
WM46_RS05650	COG2181	nitrate reductase activity
WM46_RS05655	COG0697	spore germination
WM46_RS05660	COG1522	sequence-specific DNA binding
WM46_RS05695	COG0788	formyltetrahydrofolate deformylase activity
WM46_RS05705	COG1752	Esterase of the alpha-beta hydrolase superfamily
WM46_RS05710	COG0745	RESPONSE REGULATOR receiver
WM46_RS05715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WM46_RS05725	COG1435	thymidine kinase activity
WM46_RS05730	COG1012	belongs to the aldehyde dehydrogenase family
WM46_RS05730	COG1454	alcohol dehydrogenase
WM46_RS05735	COG2095	MarC family integral membrane protein
WM46_RS05760	COG0444	Belongs to the ABC transporter superfamily
WM46_RS05765	COG4608	Belongs to the ABC transporter superfamily
WM46_RS05770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WM46_RS05785	COG2350	Protein conserved in bacteria
WM46_RS05815	COG3047	cAMP biosynthetic process
WM46_RS05825	COG3706	GGDEF domain
WM46_RS05845	COG0512	Glutamine amidotransferase of anthranilate synthase
WM46_RS05845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WM46_RS05860	COG0009	L-threonylcarbamoyladenylate synthase
WM46_RS05865	COG1187	pseudouridine synthase activity
WM46_RS05875	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS05880	COG0616	signal peptide processing
WM46_RS05925	COG0671	phosphoesterase, PA-phosphatase related
WM46_RS05930	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
WM46_RS05935	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WM46_RS05945	COG0023	Translation Initiation Factor
WM46_RS05955	COG1349	DNA-binding transcription factor activity
WM46_RS05965	COG5001	Diguanylate cyclase
WM46_RS05975	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WM46_RS05975	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WM46_RS05980	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WM46_RS05990	COG3121	Chaperone
WM46_RS05995	COG3188	usher protein
WM46_RS06010	COG3121	Chaperone
WM46_RS06020	COG3188	usher protein
WM46_RS06055	COG4171	peptide transport system, permease
WM46_RS06070	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
WM46_RS06075	COG1842	Phage shock protein A
WM46_RS06085	COG1983	PspC domain protein
WM46_RS06100	COG3106	COG3106 Predicted ATPase
WM46_RS06120	COG4948	Mandelate Racemase Muconate Lactonizing
WM46_RS06125	COG2866	Carboxypeptidase
WM46_RS06130	COG4166	transmembrane transport
WM46_RS06135	COG1349	DNA-binding transcription factor activity
WM46_RS06140	COG0346	lactoylglutathione lyase activity
WM46_RS06145	COG0668	transmembrane transport
WM46_RS06150	COG3182	Iron-regulated membrane protein
WM46_RS06165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WM46_RS06170	COG2840	Smr protein MutS2
WM46_RS06175	COG1414	Transcriptional regulator
WM46_RS06185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WM46_RS06190	COG0183	Belongs to the thiolase family
WM46_RS06200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WM46_RS06205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WM46_RS06210	COG3706	GGDEF domain
WM46_RS06220	COG0840	transmembrane signaling receptor activity
WM46_RS06235	COG0513	Belongs to the DEAD box helicase family
WM46_RS06245	COG0582	viral genome integration into host DNA
WM46_RS06250	COG2814	Major facilitator Superfamily
WM46_RS06265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WM46_RS06270	COG1013	pyruvate-flavodoxin oxidoreductase activity
WM46_RS06270	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WM46_RS06270	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WM46_RS06270	COG0674	pyruvate-flavodoxin oxidoreductase activity
WM46_RS06275	COG0791	NLP P60 protein
WM46_RS06280	COG3042	response to heat
WM46_RS06285	COG3187	Heat shock protein
WM46_RS06290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WM46_RS06295	COG2911	Protein conserved in bacteria
WM46_RS06305	COG3784	Protein of unknown function (DUF1318)
WM46_RS06310	COG0667	Aldo Keto reductase
WM46_RS06325	COG1643	Atp-dependent helicase
WM46_RS06350	COG1434	Gram-negative-bacterium-type cell wall biogenesis
WM46_RS06355	COG1012	belongs to the aldehyde dehydrogenase family
WM46_RS06360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WM46_RS06365	COG3038	cytochrome b561
WM46_RS06390	COG0840	transmembrane signaling receptor activity
WM46_RS06395	COG0583	DNA-binding transcription factor activity
WM46_RS06400	COG1227	inorganic diphosphatase activity
WM46_RS06405	COG3485	protocatechuate 3,4-dioxygenase
WM46_RS06410	COG3485	protocatechuate 3,4-dioxygenase
WM46_RS06415	COG5383	Protein conserved in bacteria
WM46_RS06420	COG2272	Belongs to the type-B carboxylesterase lipase family
WM46_RS06435	COG2841	Protein conserved in bacteria
WM46_RS06440	COG1349	DNA-binding transcription factor activity
WM46_RS06445	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WM46_RS06450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS06455	COG0434	BtpA family
WM46_RS06460	COG3775	system Galactitol-specific IIC component
WM46_RS06465	COG3414	Phosphotransferase system galactitol-specific IIB component
WM46_RS06470	COG1363	Peptidase, m42
WM46_RS06475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WM46_RS06480	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
WM46_RS06485	COG1275	C4-dicarboxylate transporter malic acid transport protein
WM46_RS06490	COG0500	methyltransferase
WM46_RS06510	COG3135	benzoate transporter
WM46_RS06515	COG1396	sequence-specific DNA binding
WM46_RS06520	COG0826	peptidase U32
WM46_RS06530	COG1294	oxidase, subunit
WM46_RS06535	COG1271	oxidase subunit
WM46_RS06540	COG1724	mRNA binding
WM46_RS06545	COG1598	PFAM Uncharacterised protein family UPF0150
WM46_RS06550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WM46_RS06555	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WM46_RS06560	COG3842	ATPase activity
WM46_RS06565	COG1176	ABC-type spermidine putrescine transport system, permease component I
WM46_RS06570	COG1177	transmembrane transport
WM46_RS06610	COG0747	negative chemotaxis
WM46_RS06620	COG3238	Protein conserved in bacteria
WM46_RS06625	COG1247	-acetyltransferase
WM46_RS06635	COG2130	NADP-dependent
WM46_RS06640	COG1802	Transcriptional regulator
WM46_RS06645	COG4772	TonB-dependent receptor
WM46_RS06660	COG0840	transmembrane signaling receptor activity
WM46_RS06665	COG0625	glutathione transferase activity
WM46_RS06670	COG2271	Major facilitator Superfamily
WM46_RS06685	COG1609	Transcriptional regulator
WM46_RS06695	COG2015	COG2015, Alkyl sulfatase and related hydrolases
WM46_RS06710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WM46_RS06715	COG2162	N-hydroxyarylamine O-acetyltransferase activity
WM46_RS06720	COG0384	phenazine biosynthesis protein PhzF
WM46_RS06730	COG2181	nitrate reductase activity
WM46_RS06735	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
WM46_RS06740	COG1140	nitrate reductase beta subunit
WM46_RS06745	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
WM46_RS06750	COG2223	nitrite transmembrane transporter activity
WM46_RS06780	COG0243	molybdopterin cofactor binding
WM46_RS06780	COG3383	formate dehydrogenase (NAD+) activity
WM46_RS06785	COG0243	molybdopterin cofactor binding
WM46_RS06785	COG3383	formate dehydrogenase (NAD+) activity
WM46_RS06790	COG0437	4 iron, 4 sulfur cluster binding
WM46_RS06795	COG2864	formate dehydrogenase
WM46_RS06805	COG3093	addiction module antidote protein HigA
WM46_RS06815	COG0488	(ABC) transporter
WM46_RS06830	COG1764	response to oxidative stress
WM46_RS06835	COG4608	Belongs to the ABC transporter superfamily
WM46_RS06840	COG0444	Belongs to the ABC transporter superfamily
WM46_RS06845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WM46_RS06850	COG0601	transmembrane transport
WM46_RS06855	COG0747	negative chemotaxis
WM46_RS06860	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
WM46_RS06875	COG0840	transmembrane signaling receptor activity
WM46_RS06880	COG2199	diguanylate cyclase activity
WM46_RS06880	COG2200	EAL domain
WM46_RS06880	COG2202	Pas domain
WM46_RS06885	COG3706	GGDEF domain
WM46_RS06910	COG1649	PFAM Uncharacterised BCR, COG1649
WM46_RS06935	COG4128	Pfam Zonular occludens toxin
WM46_RS07020	COG3781	membrane
WM46_RS07035	COG2199	diguanylate cyclase activity
WM46_RS07045	COG2066	Belongs to the glutaminase family
WM46_RS07050	COG0840	transmembrane signaling receptor activity
WM46_RS07055	COG1012	belongs to the aldehyde dehydrogenase family
WM46_RS07060	COG0583	DNA-binding transcription factor activity
WM46_RS07075	COG1846	Transcriptional regulator
WM46_RS07090	COG0697	spore germination
WM46_RS07095	COG2814	Major facilitator Superfamily
WM46_RS07105	COG1129	ABC transporter
WM46_RS07125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
WM46_RS07150	COG0339	signal peptide processing
WM46_RS07155	COG4221	oxidoreductase activity
WM46_RS07160	COG1802	Transcriptional regulator
WM46_RS07170	COG0246	Mannitol dehydrogenase
WM46_RS07180	COG4948	Mandelate Racemase Muconate Lactonizing
WM46_RS07195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WM46_RS07215	COG0243	molybdopterin cofactor binding
WM46_RS07220	COG0437	4 iron, 4 sulfur cluster binding
WM46_RS07225	COG3302	dmso reductase anchor subunit
WM46_RS07260	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WM46_RS07265	COG1940	carbohydrate kinase activity
WM46_RS07270	COG0583	DNA-binding transcription factor activity
WM46_RS07275	COG2814	Major facilitator Superfamily
WM46_RS07290	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
WM46_RS07305	COG3591	Belongs to the peptidase S1B family
WM46_RS07325	COG0628	permease
WM46_RS07330	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
WM46_RS07335	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WM46_RS07345	COG0531	amino acid
WM46_RS07355	COG3136	membrane protein required for alginate biosynthesis
WM46_RS07360	COG0745	RESPONSE REGULATOR receiver
WM46_RS07365	COG2205	protein histidine kinase activity
WM46_RS07375	COG0114	fumarate hydratase activity
WM46_RS07380	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
WM46_RS07380	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
WM46_RS07390	COG5339	Protein conserved in bacteria
WM46_RS07400	COG1263	PTS System
WM46_RS07400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS07405	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WM46_RS07410	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WM46_RS07415	COG0673	inositol 2-dehydrogenase activity
WM46_RS07455	COG4659	FMN binding
WM46_RS07465	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WM46_RS07475	COG0625	glutathione transferase activity
WM46_RS07480	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
WM46_RS07495	COG3895	Periplasmic Protein
WM46_RS07520	COG1566	PFAM secretion protein HlyD family protein
WM46_RS07525	COG1289	transmembrane transporter activity
WM46_RS07535	COG4989	oxidoreductase activity
WM46_RS07540	COG3313	Fe-S protein
WM46_RS07545	COG1309	transcriptional regulator
WM46_RS07550	COG1902	pentaerythritol trinitrate reductase activity
WM46_RS07555	COG0346	lactoylglutathione lyase activity
WM46_RS07570	COG3188	usher protein
WM46_RS07575	COG3121	Chaperone
WM46_RS07590	COG1201	RNA secondary structure unwinding
WM46_RS07595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WM46_RS07600	COG0791	NLP P60 protein
WM46_RS07610	COG2814	Major facilitator Superfamily
WM46_RS07630	COG0583	DNA-binding transcription factor activity
WM46_RS07635	COG2814	Major facilitator Superfamily
WM46_RS07640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WM46_RS07645	COG0307	riboflavin synthase, alpha
WM46_RS07670	COG4932	domain protein
WM46_RS07670	COG2373	Large extracellular alpha-helical protein
WM46_RS07670	COG1388	LysM domain
WM46_RS07690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WM46_RS07695	COG4529	Protein conserved in bacteria
WM46_RS07710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM46_RS07720	COG0765	amino acid transport
WM46_RS07725	COG0765	amino acid transport
WM46_RS07735	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
WM46_RS07740	COG0437	4 iron, 4 sulfur cluster binding
WM46_RS07750	COG2414	aldehyde ferredoxin oxidoreductase
WM46_RS07755	COG0437	4 iron, 4 sulfur cluster binding
WM46_RS07790	COG1464	Belongs to the NlpA lipoprotein family
WM46_RS07795	COG2011	ABC-type metal ion transport system permease component
WM46_RS07820	COG1376	ErfK ybiS ycfS ynhG family protein
WM46_RS07835	COG0719	Fe-S assembly protein
WM46_RS07840	COG0396	ATPase activity
WM46_RS07845	COG0719	Fe-S assembly protein
WM46_RS07850	COG0316	Belongs to the HesB IscA family
WM46_RS07870	COG2050	protein possibly involved in aromatic compounds catabolism
WM46_RS07875	COG0247	lactate metabolic process
WM46_RS07875	COG0277	FAD linked oxidase domain protein
WM46_RS07880	COG0628	permease
WM46_RS07895	COG0738	Major facilitator superfamily
WM46_RS07900	COG2271	Major facilitator Superfamily
WM46_RS07915	COG4670	ketone body catabolic process
WM46_RS07920	COG1960	acyl-CoA dehydrogenase activity
WM46_RS07925	COG2207	Transcriptional regulator
WM46_RS07925	COG1917	Cupin 2, conserved barrel domain protein
WM46_RS07930	COG2086	electron transfer activity
WM46_RS07935	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
WM46_RS07940	COG0644	oxidoreductase
WM46_RS07945	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
WM46_RS07950	COG0318	PFAM AMP-dependent synthetase and ligase
WM46_RS07955	COG0574	Belongs to the PEP-utilizing enzyme family
WM46_RS07955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WM46_RS07965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WM46_RS07970	COG4256	Hemin uptake protein
WM46_RS07985	COG0791	NLP P60 protein
WM46_RS07995	COG0386	Belongs to the glutathione peroxidase family
WM46_RS08010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WM46_RS08010	COG0072	phenylalanine-tRNA ligase activity
WM46_RS08030	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WM46_RS08065	COG3137	Salt-induced outer membrane protein
WM46_RS08070	COG1105	Belongs to the carbohydrate kinase PfkB family
WM46_RS08080	COG3001	Fructosamine kinase
WM46_RS08090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WM46_RS08095	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS08100	COG1988	membrane-bound metal-dependent
WM46_RS08105	COG1823	symporter activity
WM46_RS08115	COG0753	catalase activity
WM46_RS08125	COG1486	melibiose metabolic process
WM46_RS08130	COG1917	Cupin 2, conserved barrel domain protein
WM46_RS08130	COG2169	Transcriptional regulator
WM46_RS08135	COG1447	Phosphotransferase system cellobiose-specific component IIA
WM46_RS08140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WM46_RS08145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WM46_RS08150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WM46_RS08160	COG0322	excinuclease ABC activity
WM46_RS08170	COG3678	ATP-independent chaperone mediated protein folding
WM46_RS08200	COG0708	Exodeoxyribonuclease III
WM46_RS08210	COG4134	Bacterial extracellular solute-binding protein
WM46_RS08215	COG4135	transport system, permease component
WM46_RS08220	COG4136	ATPase activity
WM46_RS08225	COG2897	thiosulfate sulfurtransferase activity
WM46_RS08230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WM46_RS08235	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WM46_RS08240	COG0494	nUDIX hydrolase
WM46_RS08255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WM46_RS08265	COG1737	Transcriptional regulator
WM46_RS08280	COG2190	(PTS) system
WM46_RS08280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS08280	COG1263	PTS System
WM46_RS08285	COG0641	radical SAM
WM46_RS08290	COG0778	Nitroreductase
WM46_RS08300	COG0616	signal peptide processing
WM46_RS08305	COG0252	asparaginase activity
WM46_RS08310	COG1335	isochorismatase
WM46_RS08330	COG3139	Protein of unknown function (DUF1315)
WM46_RS08350	COG0656	L-ascorbic acid biosynthetic process
WM46_RS08355	COG3713	MltA-interacting MipA family protein
WM46_RS08360	COG2766	serine protein kinase
WM46_RS08370	COG2199	diguanylate cyclase activity
WM46_RS08375	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WM46_RS08390	COG2207	Transcriptional regulator
WM46_RS08395	COG2807	transmembrane transport
WM46_RS08400	COG0504	CTP synthase activity
WM46_RS08405	COG1683	Conserved Protein
WM46_RS08410	COG3189	MarR family transcriptional regulator
WM46_RS08430	COG2261	transglycosylase associated protein
WM46_RS08435	COG3383	formate dehydrogenase (NAD+) activity
WM46_RS08460	COG3710	Transcriptional regulator
WM46_RS08465	COG0538	isocitrate dehydrogenase activity
WM46_RS08470	COG1187	pseudouridine synthase activity
WM46_RS08490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WM46_RS08505	COG2850	peptidyl-arginine hydroxylation
WM46_RS08525	COG1177	transmembrane transport
WM46_RS08535	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
WM46_RS08545	COG4591	ABC-type transport system involved in lipoprotein release permease component
WM46_RS08550	COG1136	(ABC) transporter
WM46_RS08555	COG4591	ABC-type transport system involved in lipoprotein release permease component
WM46_RS08560	COG4763	Acyl-transferase
WM46_RS08565	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WM46_RS08570	COG1388	LysM domain
WM46_RS08570	COG1376	ErfK ybiS ycfS ynhG family protein
WM46_RS08580	COG1309	transcriptional regulator
WM46_RS08590	COG3134	Outer membrane lipoprotein
WM46_RS08595	COG1252	NADH dehydrogenase
WM46_RS08615	COG0510	thiamine kinase activity
WM46_RS08625	COG5633	Lipoprotein
WM46_RS08630	COG0537	adenosine 5'-monophosphoramidase activity
WM46_RS08635	COG4773	Receptor
WM46_RS08645	COG0084	hydrolase, TatD family'
WM46_RS08650	COG0470	DNA polymerase III
WM46_RS08660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WM46_RS08665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WM46_RS08670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WM46_RS08680	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS08685	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
WM46_RS08705	COG1399	metal-binding, possibly nucleic acid-binding protein
WM46_RS08715	COG0564	pseudouridine synthase activity
WM46_RS08725	COG1530	ribonuclease E activity
WM46_RS08730	COG0583	DNA-binding transcription factor activity
WM46_RS08735	COG2814	Major facilitator Superfamily
WM46_RS08740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WM46_RS08745	COG1256	bacterial-type flagellum assembly
WM46_RS08765	COG4786	Flagellar basal body rod
WM46_RS08770	COG4787	bacterial-type flagellum-dependent cell motility
WM46_RS08785	COG1558	bacterial-type flagellum-dependent cell motility
WM46_RS08815	COG0728	peptidoglycan biosynthetic process
WM46_RS08830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WM46_RS08840	COG2999	glutathione oxidoreductase activity
WM46_RS08875	COG3038	cytochrome b561
WM46_RS08890	COG1560	Kdo2-lipid A biosynthetic process
WM46_RS08905	COG5645	(Lipo)protein
WM46_RS08925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WM46_RS08930	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
WM46_RS08980	COG3381	protein complex oligomerization
WM46_RS09075	COG3157	Type VI secretion system effector, Hcp
WM46_RS09100	COG1702	phosphate starvation-inducible protein PhoH
WM46_RS09120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WM46_RS09130	COG0506	proline dehydrogenase activity
WM46_RS09130	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WM46_RS09130	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WM46_RS09140	COG1309	transcriptional regulator
WM46_RS09145	COG3729	General stress protein
WM46_RS09165	COG0640	Transcriptional regulator
WM46_RS09185	COG1136	(ABC) transporter
WM46_RS09185	COG0577	efflux transmembrane transporter activity
WM46_RS09195	COG0577	efflux transmembrane transporter activity
WM46_RS09195	COG1136	(ABC) transporter
WM46_RS09210	COG0672	)-iron permease
WM46_RS09215	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WM46_RS09220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WM46_RS09225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WM46_RS09225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WM46_RS09250	COG0348	domain, Protein
WM46_RS09255	COG0628	permease
WM46_RS09275	COG2271	Major facilitator Superfamily
WM46_RS09280	COG0800	Aldolase
WM46_RS09285	COG1414	Transcriptional regulator
WM46_RS09295	COG0306	phosphate transporter
WM46_RS09300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WM46_RS09305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WM46_RS09310	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WM46_RS09315	COG2244	polysaccharide biosynthetic process
WM46_RS09325	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
WM46_RS09330	COG0795	lipopolysaccharide-transporting ATPase activity
WM46_RS09340	COG0156	8-amino-7-oxononanoate synthase activity
WM46_RS09345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WM46_RS09360	COG0456	acetyltransferase
WM46_RS09370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM46_RS09375	COG1869	D-ribose catabolic process
WM46_RS09380	COG1064	alcohol dehydrogenase
WM46_RS09385	COG4948	Mandelate Racemase Muconate Lactonizing
WM46_RS09390	COG0667	Aldo Keto reductase
WM46_RS09405	COG1454	alcohol dehydrogenase
WM46_RS09410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WM46_RS09430	COG3711	transcriptional antiterminator
WM46_RS09435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS09455	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
WM46_RS09460	COG3153	acetyltransferase
WM46_RS09480	COG3655	Transcriptional regulator
WM46_RS09490	COG0159	tryptophan synthase activity
WM46_RS09520	COG1414	Transcriptional regulator
WM46_RS09525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WM46_RS09530	COG0129	dihydroxy-acid dehydratase activity
WM46_RS09535	COG2610	gluconate transmembrane transporter activity
WM46_RS09550	COG1609	Transcriptional regulator
WM46_RS09555	COG1757	Na H antiporter
WM46_RS09560	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WM46_RS09580	COG0670	Belongs to the BI1 family
WM46_RS09605	COG1832	CoA-binding protein
WM46_RS09620	COG0210	DNA helicase
WM46_RS09625	COG3304	Inner membrane component domain
WM46_RS09630	COG1289	transmembrane transporter activity
WM46_RS09635	COG3070	regulator of competence-specific genes
WM46_RS09655	COG1067	ATP-dependent peptidase activity
WM46_RS09665	COG3130	regulation of translation
WM46_RS09670	COG3009	Protein conserved in bacteria
WM46_RS09675	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WM46_RS09675	COG3008	intermembrane lipid transfer
WM46_RS09680	COG2995	paraquat-inducible protein a
WM46_RS09685	COG0488	(ABC) transporter
WM46_RS09695	COG0633	Ferredoxin
WM46_RS09695	COG3217	Mosc domain protein beta barrel domain protein
WM46_RS09715	COG0431	NADPH-dependent FMN reductase
WM46_RS09720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WM46_RS09730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WM46_RS09740	COG0308	aminopeptidase N
WM46_RS09760	COG1448	Aminotransferase
WM46_RS09765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WM46_RS09770	COG3108	Peptidase M15
WM46_RS09780	COG2989	Protein conserved in bacteria
WM46_RS09790	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
WM46_RS09800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WM46_RS09805	COG1434	Gram-negative-bacterium-type cell wall biogenesis
WM46_RS09810	COG3173	Aminoglycoside phosphotransferase
WM46_RS09825	COG3214	Protein conserved in bacteria
WM46_RS09840	COG0658	competence protein
WM46_RS09840	COG2333	competence protein COMEC
WM46_RS09845	COG0776	regulation of translation
WM46_RS09850	COG0539	negative regulation of cytoplasmic translation
WM46_RS09860	COG0501	Belongs to the peptidase M48B family
WM46_RS09875	COG2323	membrane
WM46_RS09880	COG1944	ATP diphosphatase activity
WM46_RS09885	COG2116	formate transmembrane transporter activity
WM46_RS09890	COG1882	Formate acetyltransferase
WM46_RS09895	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WM46_RS09905	COG1335	isochorismatase
WM46_RS09910	COG3302	dmso reductase anchor subunit
WM46_RS09915	COG0437	4 iron, 4 sulfur cluster binding
WM46_RS09920	COG0243	molybdopterin cofactor binding
WM46_RS09930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WM46_RS09955	COG0492	ferredoxin-NADP+ reductase activity
WM46_RS09960	COG4988	ABC transporter
WM46_RS09965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WM46_RS09980	COG0583	DNA-binding transcription factor activity
WM46_RS10015	COG0542	response to heat
WM46_RS10025	COG1278	Cold shock
WM46_RS10035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM46_RS10040	COG2990	Protein conserved in bacteria
WM46_RS10045	COG3593	DNA synthesis involved in DNA repair
WM46_RS10055	COG2431	L-lysine efflux transmembrane transporter activity
WM46_RS10065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WM46_RS10075	COG0028	Belongs to the TPP enzyme family
WM46_RS10080	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
WM46_RS10085	COG0702	epimerase
WM46_RS10090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WM46_RS10095	COG3023	N-Acetylmuramoyl-L-alanine amidase
WM46_RS10110	COG1126	abc transporter atp-binding protein
WM46_RS10115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM46_RS10120	COG4215	(ABC) transporter
WM46_RS10125	COG4160	amino acid transport
WM46_RS10130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM46_RS10145	COG1177	transmembrane transport
WM46_RS10150	COG1176	ABC-type spermidine putrescine transport system, permease component I
WM46_RS10155	COG3842	ATPase activity
WM46_RS10160	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WM46_RS10210	COG3226	Transcriptional regulator
WM46_RS10215	COG0738	Major facilitator superfamily
WM46_RS10220	COG0561	phosphatase activity
WM46_RS10225	COG2814	Major facilitator Superfamily
WM46_RS10230	COG0671	phosphoesterase, PA-phosphatase related
WM46_RS10235	COG1349	DNA-binding transcription factor activity
WM46_RS10240	COG1686	Belongs to the peptidase S11 family
WM46_RS10245	COG0625	glutathione transferase activity
WM46_RS10255	COG2133	pyrroloquinoline quinone binding
WM46_RS10280	COG0747	negative chemotaxis
WM46_RS10290	COG1446	asparaginase
WM46_RS10295	COG0303	'Molybdopterin
WM46_RS10300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WM46_RS10305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WM46_RS10310	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WM46_RS10315	COG1882	Formate acetyltransferase
WM46_RS10320	COG0561	phosphatase activity
WM46_RS10330	COG1609	Transcriptional regulator
WM46_RS10335	COG2271	Major facilitator Superfamily
WM46_RS10350	COG0488	(ABC) transporter
WM46_RS10355	COG1376	ErfK ybiS ycfS ynhG family protein
WM46_RS10370	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WM46_RS10385	COG2194	sulfuric ester hydrolase activity
WM46_RS10390	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WM46_RS10400	COG5006	permease, DMT superfamily
WM46_RS10410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM46_RS10415	COG0765	amino acid transport
WM46_RS10420	COG1126	abc transporter atp-binding protein
WM46_RS10425	COG0668	transmembrane transport
WM46_RS10440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WM46_RS10455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WM46_RS10460	COG1199	ATP-dependent helicase activity
WM46_RS10465	COG0471	metal ion transport
WM46_RS10475	COG2188	Transcriptional regulator
WM46_RS10485	COG0513	Belongs to the DEAD box helicase family
WM46_RS10490	COG1309	transcriptional regulator
WM46_RS10495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM46_RS10500	COG1131	(ABC) transporter
WM46_RS10505	COG0842	Transport permease protein
WM46_RS10510	COG0842	Transport permease protein
WM46_RS10520	COG3568	Endonuclease Exonuclease Phosphatase
WM46_RS10525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WM46_RS10530	COG0392	lysyltransferase activity
WM46_RS10535	COG0670	Belongs to the BI1 family
WM46_RS10540	COG0314	molybdopterin synthase activity
WM46_RS10545	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WM46_RS10555	COG0521	Mo-molybdopterin cofactor biosynthetic process
WM46_RS10575	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WM46_RS10580	COG2226	methyltransferase
WM46_RS10600	COG1881	PFAM PEBP family protein
WM46_RS10630	COG4677	pectinesterase activity
WM46_RS10640	COG0561	phosphatase activity
WM46_RS10650	COG4149	molybdate abc transporter
WM46_RS10655	COG0725	ABC transporter, periplasmic molybdate-binding protein
WM46_RS10665	COG3585	molybdate ion transport
WM46_RS10665	COG2005	Transcriptional regulator
WM46_RS10670	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
WM46_RS10670	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
WM46_RS10675	COG1703	isobutyryl-CoA mutase activity
WM46_RS10680	COG1024	Enoyl-CoA hydratase
WM46_RS10685	COG0427	acetyl-CoA hydrolase
WM46_RS10695	COG1119	ATPase activity
WM46_RS10700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WM46_RS10705	COG1085	galactose-1-phosphate uridylyltransferase
WM46_RS10715	COG2017	converts alpha-aldose to the beta-anomer
WM46_RS10730	COG1120	ATPase activity
WM46_RS10735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM46_RS10740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WM46_RS10755	COG1230	cation diffusion facilitator family transporter
WM46_RS10760	COG3201	nicotinamide mononucleotide transporter
WM46_RS10795	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
WM46_RS10800	COG2885	chlorophyll binding
WM46_RS10810	COG3064	Membrane
WM46_RS10815	COG0848	biopolymer transport protein
WM46_RS10820	COG0811	peptide transport
WM46_RS10825	COG0824	Thioesterase
WM46_RS10830	COG3790	cyd operon protein YbgE
WM46_RS10835	COG4890	Cyd operon protein YbgT
WM46_RS10840	COG1294	oxidase, subunit
WM46_RS10845	COG1271	oxidase subunit
WM46_RS10850	COG0383	alpha-mannosidase activity
WM46_RS10855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM46_RS10855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM46_RS10855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS10860	COG2188	Transcriptional regulator
WM46_RS10865	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
WM46_RS10875	COG4865	methylaspartate mutase activity
WM46_RS10880	COG3799	methylaspartate ammonia-lyase activity
WM46_RS10895	COG1301	dicarboxylic acid transport
WM46_RS10905	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
WM46_RS10905	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
WM46_RS10910	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
WM46_RS10915	COG0583	DNA-binding transcription factor activity
WM46_RS10920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WM46_RS10920	COG1648	precorrin-2 dehydrogenase activity
WM46_RS10930	COG3395	kinase activity
WM46_RS10935	COG0235	Class ii aldolase
WM46_RS10940	COG1349	DNA-binding transcription factor activity
WM46_RS10945	COG3622	Belongs to the hyi family
WM46_RS10950	COG3246	L-lysine catabolic process to acetate
WM46_RS10970	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WM46_RS10980	COG0508	dehydrogenase complex catalyzes the overall conversion of
WM46_RS10985	COG0567	Dehydrogenase, E1 component
WM46_RS10995	COG1053	succinate dehydrogenase
WM46_RS11000	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WM46_RS11005	COG2009	succinate dehydrogenase
WM46_RS11025	COG3180	Ammonia monooxygenase
WM46_RS11055	COG1984	allophanate hydrolase subunit 2
WM46_RS11060	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WM46_RS11070	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WM46_RS11075	COG0415	Belongs to the DNA photolyase family
WM46_RS11080	COG3272	Protein of unknown function (DUF1722)
WM46_RS11110	COG2205	protein histidine kinase activity
WM46_RS11115	COG0745	RESPONSE REGULATOR receiver
WM46_RS11125	COG1982	Orn Lys Arg decarboxylase major
WM46_RS11130	COG0531	amino acid
WM46_RS11145	COG0033	Phosphoglucomutase
WM46_RS11150	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
WM46_RS11155	COG0596	Alpha beta hydrolase
WM46_RS11165	COG0716	FMN binding
WM46_RS11170	COG0735	belongs to the Fur family
WM46_RS11180	COG1053	succinate dehydrogenase
WM46_RS11210	COG2190	(PTS) system
WM46_RS11210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS11210	COG1263	PTS System
WM46_RS11225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WM46_RS11230	COG1846	Transcriptional regulator
WM46_RS11230	COG1940	carbohydrate kinase activity
WM46_RS11235	COG0647	UMP catabolic process
WM46_RS11245	COG0367	asparagine synthase
WM46_RS11290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WM46_RS11300	COG1702	phosphate starvation-inducible protein PhoH
WM46_RS11325	COG0765	amino acid transport
WM46_RS11330	COG0765	amino acid transport
WM46_RS11335	COG1126	abc transporter atp-binding protein
WM46_RS11345	COG2888	peptidyl-tyrosine sulfation
WM46_RS11360	COG1466	dna polymerase III delta subunit
WM46_RS11375	COG0406	alpha-ribazole phosphatase activity
WM46_RS11380	COG0799	negative regulation of ribosome biogenesis
WM46_RS11390	COG0768	penicillin binding
WM46_RS11395	COG0772	Belongs to the SEDS family
WM46_RS11400	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WM46_RS11405	COG1686	Belongs to the peptidase S11 family
WM46_RS11420	COG0583	DNA-binding transcription factor activity
WM46_RS11435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WM46_RS11455	COG3069	C4-dicarboxylate transmembrane transporter activity
WM46_RS11460	COG4565	transcriptional regulatory protein
WM46_RS11465	COG3290	protein histidine kinase activity
WM46_RS11475	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
WM46_RS11485	COG2301	Belongs to the HpcH HpaI aldolase family
WM46_RS11490	COG3051	citrate lyase alpha subunit
WM46_RS11505	COG0471	metal ion transport
WM46_RS11510	COG3719	Belongs to the RNase T2 family
WM46_RS11515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WM46_RS11525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WM46_RS11535	COG3634	alkyl hydroperoxide reductase activity
WM46_RS11545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WM46_RS11550	COG3969	phosphoadenosine phosphosulfate
WM46_RS11555	COG1475	DNA binding
WM46_RS11560	COG2879	small protein
WM46_RS11565	COG1966	Carbon starvation protein
WM46_RS11575	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS11580	COG3433	isochorismatase activity
WM46_RS11580	COG1535	isochorismatase
WM46_RS11585	COG1021	2,3-dihydroxybenzoate-AMP ligase
WM46_RS11590	COG1169	isochorismate synthase
WM46_RS11595	COG4592	Periplasmic binding protein
WM46_RS11605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM46_RS11610	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM46_RS11615	COG1120	ATPase activity
WM46_RS11620	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
WM46_RS11625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WM46_RS11625	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
WM46_RS11630	COG3251	PFAM MbtH domain protein
WM46_RS11635	COG2382	esterase
WM46_RS11640	COG4771	TonB-dependent receptor
WM46_RS11645	COG2977	Belongs to the P-Pant transferase superfamily
WM46_RS11650	COG1879	ABC-type sugar transport system periplasmic component
WM46_RS11660	COG1129	ABC transporter
WM46_RS11665	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM46_RS11670	COG2390	Transcriptional regulator
WM46_RS11675	COG3959	Transketolase, thiamine diphosphate binding domain
WM46_RS11680	COG3958	Transketolase
WM46_RS11690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WM46_RS11705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WM46_RS11750	COG2207	Transcriptional regulator
WM46_RS11765	COG2315	Protein conserved in bacteria
WM46_RS11770	COG0778	Nitroreductase
WM46_RS11775	COG0668	transmembrane transport
WM46_RS11780	COG1609	Transcriptional regulator
WM46_RS11785	COG0673	inositol 2-dehydrogenase activity
WM46_RS11795	COG2211	Major facilitator Superfamily
WM46_RS11800	COG1113	amino acid transport
WM46_RS11840	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WM46_RS11845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM46_RS11850	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM46_RS11855	COG1538	Outer membrane efflux protein
WM46_RS11860	COG0745	RESPONSE REGULATOR receiver
WM46_RS11865	COG5002	protein histidine kinase activity
WM46_RS11885	COG5002	protein histidine kinase activity
WM46_RS11915	COG2814	Major facilitator Superfamily
WM46_RS11920	COG1522	sequence-specific DNA binding
WM46_RS11935	COG0583	DNA-binding transcription factor activity
WM46_RS11950	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
WM46_RS11955	COG0656	L-ascorbic acid biosynthetic process
WM46_RS11960	COG0667	Aldo Keto reductase
WM46_RS11970	COG0702	epimerase
WM46_RS11985	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS12175	COG0582	viral genome integration into host DNA
WM46_RS12190	COG2501	S4 domain
WM46_RS12195	COG2190	(PTS) system
WM46_RS12195	COG1263	PTS System
WM46_RS12195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS12200	COG1609	Transcriptional regulator
WM46_RS12205	COG1988	membrane-bound metal-dependent
WM46_RS12215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WM46_RS12235	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WM46_RS12240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WM46_RS12255	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WM46_RS12260	COG4181	ATPase activity
WM46_RS12265	COG2755	lipolytic protein G-D-S-L family
WM46_RS12270	COG0300	oxidoreductase activity
WM46_RS12275	COG3118	belongs to the thioredoxin family
WM46_RS12280	COG0390	transport system, permease component
WM46_RS12285	COG4619	ABC transporter
WM46_RS12290	COG0330	HflC and HflK could
WM46_RS12295	COG1585	Membrane protein implicated in regulation of membrane protease activity
WM46_RS12320	COG2217	Heavy metal translocating P-type atpase
WM46_RS12325	COG3735	TraB family
WM46_RS12340	COG2223	nitrite transmembrane transporter activity
WM46_RS12345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WM46_RS12345	COG4651	solute:proton antiporter activity
WM46_RS12350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM46_RS12405	COG2832	Protein of unknown function (DUF454)
WM46_RS12410	COG3923	Primosomal replication protein n
WM46_RS12420	COG3264	Mechanosensitive ion channel
WM46_RS12420	COG1196	nuclear chromosome segregation
WM46_RS12430	COG1309	transcriptional regulator
WM46_RS12435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM46_RS12440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WM46_RS12455	COG0110	maltose O-acetyltransferase activity
WM46_RS12465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
WM46_RS12470	COG4943	cyclic-guanylate-specific phosphodiesterase activity
WM46_RS12475	COG5507	3-demethylubiquinone-9 3-methyltransferase
WM46_RS12480	COG2364	Membrane
WM46_RS12485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WM46_RS12540	COG3695	enzyme binding
WM46_RS12545	COG3126	Type III secretion system lipoprotein chaperone (YscW)
WM46_RS12550	COG1946	Acyl-CoA thioesterase
WM46_RS12555	COG0004	ammonium transporteR
WM46_RS12560	COG0347	Belongs to the P(II) protein family
WM46_RS12565	COG1132	(ABC) transporter
WM46_RS12570	COG1132	(ABC) transporter
WM46_RS12575	COG1522	sequence-specific DNA binding
WM46_RS12590	COG4533	DNA binding
WM46_RS12600	COG0824	Thioesterase
WM46_RS12605	COG1555	photosystem II stabilization
WM46_RS12610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WM46_RS12615	COG0776	regulation of translation
WM46_RS12620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WM46_RS12645	COG0271	Belongs to the BolA IbaG family
WM46_RS12650	COG3056	Lipoprotein
WM46_RS12655	COG2223	nitrite transmembrane transporter activity
WM46_RS12665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
WM46_RS12670	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WM46_RS12675	COG1845	cytochrome c oxidase, subunit III
WM46_RS12680	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WM46_RS12690	COG2814	Major facilitator Superfamily
WM46_RS12715	COG0437	4 iron, 4 sulfur cluster binding
WM46_RS12720	COG0243	molybdopterin cofactor binding
WM46_RS12740	COG0142	geranyltranstransferase activity
WM46_RS12750	COG0667	Aldo Keto reductase
WM46_RS12755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WM46_RS12775	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WM46_RS12775	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WM46_RS12785	COG4238	major outer membrane lipoprotein
WM46_RS12790	COG3248	Nucleoside-binding outer membrane protein
WM46_RS12805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WM46_RS12810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WM46_RS12815	COG1862	Preprotein translocase
WM46_RS12835	COG0450	alkyl hydroperoxide reductase
WM46_RS12840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS12855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM46_RS12875	COG1574	metal-dependent hydrolase with the TIM-barrel fold
WM46_RS12885	COG1335	isochorismatase
WM46_RS12890	COG0583	DNA-binding transcription factor activity
WM46_RS12895	COG0366	Alpha amylase catalytic
WM46_RS12900	COG1113	amino acid transport
WM46_RS12910	COG5002	protein histidine kinase activity
WM46_RS12920	COG0420	3'-5' exonuclease activity
WM46_RS12925	COG0419	ATPase involved in DNA repair
WM46_RS12930	COG2814	Major facilitator Superfamily
WM46_RS12935	COG1940	carbohydrate kinase activity
WM46_RS12945	COG3123	guanosine phosphorylase activity
WM46_RS12950	COG4126	flavin adenine dinucleotide binding
WM46_RS12970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WM46_RS12985	COG1785	Belongs to the alkaline phosphatase family
WM46_RS13005	COG1181	Belongs to the D-alanine--D-alanine ligase family
WM46_RS13025	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
WM46_RS13040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WM46_RS13045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WM46_RS13055	COG0113	porphobilinogen synthase activity
WM46_RS13065	COG2175	clavaminate synthase activity
WM46_RS13070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WM46_RS13075	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WM46_RS13080	COG4521	taurine ABC transporter
WM46_RS13105	COG2271	Major facilitator Superfamily
WM46_RS13110	COG1840	ABC-type Fe3 transport system, periplasmic component
WM46_RS13120	COG3842	ATPase activity
WM46_RS13125	COG2040	homocysteine
WM46_RS13130	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
WM46_RS13140	COG1609	Transcriptional regulator
WM46_RS13150	COG2223	nitrite transmembrane transporter activity
WM46_RS13155	COG0110	maltose O-acetyltransferase activity
WM46_RS13180	COG3829	transcription factor binding
WM46_RS13200	COG1280	lysine exporter protein (LysE YggA)
WM46_RS13220	COG2814	Major facilitator Superfamily
WM46_RS13235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WM46_RS13240	COG1064	alcohol dehydrogenase
WM46_RS13260	COG1120	ATPase activity
WM46_RS13265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM46_RS13295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WM46_RS13300	COG4774	siderophore transport
WM46_RS13300	COG1629	transport
WM46_RS13305	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM46_RS13310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM46_RS13315	COG4592	Periplasmic binding protein
WM46_RS13320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WM46_RS13330	COG1846	Transcriptional regulator
WM46_RS13345	COG1012	belongs to the aldehyde dehydrogenase family
WM46_RS13350	COG3384	dioxygenase
WM46_RS13360	COG3971	2-oxopent-4-enoate hydratase activity
WM46_RS13380	COG2368	4-hydroxyphenylacetate
WM46_RS13385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WM46_RS13400	COG2826	transposase and inactivated derivatives, IS30 family
WM46_RS13420	COG1595	DNA-templated transcription, initiation
WM46_RS13425	COG3712	iron ion homeostasis
WM46_RS13430	COG4772	TonB-dependent receptor
WM46_RS13435	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
WM46_RS13440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM46_RS13445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM46_RS13450	COG1120	ATPase activity
WM46_RS13455	COG0582	viral genome integration into host DNA
WM46_RS13465	COG3772	lysozyme
WM46_RS13475	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WM46_RS13475	COG2755	lipolytic protein G-D-S-L family
WM46_RS13635	COG0582	viral genome integration into host DNA
WM46_RS13655	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WM46_RS13675	COG2195	Cleaves the N-terminal amino acid of tripeptides
WM46_RS13680	COG0454	-acetyltransferase
WM46_RS13710	COG3034	peptidoglycan biosynthetic process
WM46_RS13715	COG0121	glutamine amidotransferase
WM46_RS13725	COG1960	acyl-CoA dehydrogenase activity
WM46_RS13730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WM46_RS13740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WM46_RS13750	COG2226	methyltransferase
WM46_RS13760	COG1388	LysM domain
WM46_RS13760	COG0741	lytic transglycosylase activity
WM46_RS13765	COG2226	methyltransferase
WM46_RS13775	COG2814	Major facilitator Superfamily
WM46_RS13780	COG0583	DNA-binding transcription factor activity
WM46_RS13815	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WM46_RS13825	COG2011	ABC-type metal ion transport system permease component
WM46_RS13830	COG1464	Belongs to the NlpA lipoprotein family
WM46_RS13840	COG1720	tRNA m6t6A37 methyltransferase activity
WM46_RS13850	COG0791	NLP P60 protein
WM46_RS13855	COG3015	lipoprotein NlpE involved in copper resistance
WM46_RS13860	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WM46_RS13875	COG4568	rho-dependent transcription termination
WM46_RS13880	COG0037	tRNA processing
WM46_RS13885	COG0346	lactoylglutathione lyase activity
WM46_RS13890	COG1982	Orn Lys Arg decarboxylase major
WM46_RS13930	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
WM46_RS13945	COG0575	Belongs to the CDS family
WM46_RS13955	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WM46_RS14005	COG3835	regulator
WM46_RS14010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WM46_RS14030	COG2860	membrane
WM46_RS14050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM46_RS14055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WM46_RS14060	COG1120	ATPase activity
WM46_RS14065	COG4774	siderophore transport
WM46_RS14070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WM46_RS14075	COG1643	Atp-dependent helicase
WM46_RS14080	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
WM46_RS14105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WM46_RS14115	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WM46_RS14125	COG0726	polysaccharide deacetylase
WM46_RS14130	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS14135	COG0842	Transport permease protein
WM46_RS14140	COG1131	(ABC) transporter
WM46_RS14145	COG0288	reversible hydration of carbon dioxide
WM46_RS14150	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
WM46_RS14155	COG4993	Dehydrogenase
WM46_RS14170	COG2132	Multicopper oxidase
WM46_RS14205	COG1349	DNA-binding transcription factor activity
WM46_RS14240	COG3064	Membrane
WM46_RS14250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WM46_RS14255	COG0508	dehydrogenase complex catalyzes the overall conversion of
WM46_RS14260	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WM46_RS14270	COG1113	amino acid transport
WM46_RS14275	COG2211	Major facilitator Superfamily
WM46_RS14280	COG3940	Belongs to the glycosyl hydrolase 43 family
WM46_RS14285	COG3725	Membrane protein required for beta-lactamase induction
WM46_RS14300	COG4969	Belongs to the N-Me-Phe pilin family
WM46_RS14305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WM46_RS14310	COG1459	type II secretion system
WM46_RS14335	COG0494	nUDIX hydrolase
WM46_RS14355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WM46_RS14360	COG0849	cell division
WM46_RS14370	COG1181	Belongs to the D-alanine--D-alanine ligase family
WM46_RS14385	COG0772	Belongs to the SEDS family
WM46_RS14395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WM46_RS14400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WM46_RS14405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WM46_RS14410	COG0768	penicillin binding
WM46_RS14430	COG1609	Transcriptional regulator
WM46_RS14440	COG0028	Belongs to the TPP enzyme family
WM46_RS14475	COG2814	Major facilitator Superfamily
WM46_RS14500	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
WM46_RS14505	COG0586	Pfam SNARE associated Golgi protein
WM46_RS14510	COG4977	sequence-specific DNA binding
WM46_RS14525	COG0235	Class ii aldolase
WM46_RS14530	COG0417	DNA replication proofreading
WM46_RS14540	COG0564	pseudouridine synthase activity
WM46_RS14545	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WM46_RS14550	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WM46_RS14555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WM46_RS14605	COG2271	Major facilitator Superfamily
WM46_RS14615	COG0644	oxidoreductase
WM46_RS14640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WM46_RS14670	COG0505	Belongs to the CarA family
WM46_RS14680	COG1957	nucleoside hydrolase
WM46_RS14690	COG1047	Peptidyl-prolyl cis-trans
WM46_RS14705	COG0196	riboflavin kinase activity
WM46_RS14720	COG0583	DNA-binding transcription factor activity
WM46_RS14735	COG0641	radical SAM
WM46_RS14740	COG3119	arylsulfatase activity
WM46_RS14750	COG0737	Belongs to the 5'-nucleotidase family
WM46_RS14770	COG1584	GPR1 FUN34 yaaH family protein
WM46_RS14775	COG0477	Major facilitator Superfamily
WM46_RS14780	COG0521	Mo-molybdopterin cofactor biosynthetic process
WM46_RS14790	COG1115	amino acid carrier protein
WM46_RS14800	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
WM46_RS14810	COG0527	aspartate kinase activity
WM46_RS14810	COG0460	homoserine dehydrogenase
WM46_RS14820	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
WM46_RS14830	COG0745	RESPONSE REGULATOR receiver
WM46_RS14835	COG4452	Inner membrane protein CreD
WM46_RS14840	COG2205	protein histidine kinase activity
WM46_RS14845	COG0745	RESPONSE REGULATOR receiver
WM46_RS14850	COG3045	CreA protein
WM46_RS14855	COG3708	Transcriptional regulator
WM46_RS14855	COG2207	Transcriptional regulator
WM46_RS14875	COG0741	lytic transglycosylase activity
WM46_RS14880	COG0488	(ABC) transporter
WM46_RS14885	COG2968	Membrane
WM46_RS14890	COG1279	arginine transmembrane transporter activity
WM46_RS14895	COG0668	transmembrane transport
WM46_RS14900	COG0583	DNA-binding transcription factor activity
WM46_RS14910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WM46_RS14915	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WM46_RS14920	COG2271	Major facilitator Superfamily
WM46_RS14925	COG0549	Belongs to the carbamate kinase family
WM46_RS14930	COG0191	fructose-bisphosphate aldolase activity
WM46_RS14960	COG1122	ATPase activity
WM46_RS14965	COG1122	ATPase activity
WM46_RS14970	COG1072	(Pantothenic acid kinase))
WM46_RS14980	COG1494	fructose-1,6-bisphosphatase
WM46_RS14985	COG1063	alcohol dehydrogenase
WM46_RS14990	COG2213	PTS system mannitol-specific
WM46_RS14995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS15000	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WM46_RS15005	COG0501	Belongs to the peptidase M48B family
WM46_RS15015	COG1166	arginine decarboxylase activity
WM46_RS15040	COG2814	Major facilitator Superfamily
WM46_RS15045	COG3091	SprT-like family
WM46_RS15050	COG2356	endonuclease I
WM46_RS15055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WM46_RS15060	COG0189	ligase activity
WM46_RS15075	COG2805	Type II/IV secretion system protein
WM46_RS15080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WM46_RS15085	COG0762	integral membrane protein
WM46_RS15100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WM46_RS15110	COG0252	asparaginase activity
WM46_RS15120	COG3171	Protein conserved in bacteria
WM46_RS15135	COG1194	a g-specific adenine glycosylase
WM46_RS15150	COG2211	Major facilitator Superfamily
WM46_RS15155	COG1982	Orn Lys Arg decarboxylase major
WM46_RS15160	COG1811	Na channel or pump
WM46_RS15170	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WM46_RS15180	COG0210	DNA helicase
WM46_RS15185	COG2826	transposase and inactivated derivatives, IS30 family
WM46_RS15190	COG2249	NAD(P)H dehydrogenase (quinone) activity
WM46_RS15200	COG1733	regulation of RNA biosynthetic process
WM46_RS15205	COG0604	alcohol dehydrogenase
WM46_RS15205	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS15205	COG3321	synthase
WM46_RS15210	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS15215	COG2207	Transcriptional regulator
WM46_RS15225	COG1566	PFAM secretion protein HlyD family protein
WM46_RS15320	COG2723	6-phospho-beta-galactosidase activity
WM46_RS15345	COG2223	nitrite transmembrane transporter activity
WM46_RS15355	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WM46_RS15360	COG1733	regulation of RNA biosynthetic process
WM46_RS15370	COG2723	6-phospho-beta-galactosidase activity
WM46_RS15375	COG1609	Transcriptional regulator
WM46_RS15380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS15380	COG1263	PTS System
WM46_RS15380	COG2190	(PTS) system
WM46_RS15390	COG1595	DNA-templated transcription, initiation
WM46_RS15400	COG4178	(ABC) transporter
WM46_RS15410	COG0848	biopolymer transport protein
WM46_RS15485	COG3226	Transcriptional regulator
WM46_RS15490	COG0738	Major facilitator superfamily
WM46_RS15495	COG0561	phosphatase activity
WM46_RS15535	COG2249	NAD(P)H dehydrogenase (quinone) activity
WM46_RS15540	COG1733	regulation of RNA biosynthetic process
WM46_RS15575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM46_RS15585	COG1538	Outer membrane efflux protein
WM46_RS15640	COG3547	Transposase (IS116 IS110 IS902 family)
WM46_RS15660	COG0629	single-stranded DNA binding
WM46_RS15670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WM46_RS15700	COG0582	viral genome integration into host DNA
WM46_RS15805	COG3547	Transposase (IS116 IS110 IS902 family)
WM46_RS15830	COG3596	GTP binding
WM46_RS15865	COG2003	Belongs to the UPF0758 family
WM46_RS15890	COG0754	glutathionylspermidine amidase activity
WM46_RS15895	COG0625	glutathione transferase activity
WM46_RS15905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WM46_RS15910	COG0298	carbon dioxide binding
WM46_RS15920	COG1773	rubredoxin
WM46_RS15925	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
WM46_RS15930	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
WM46_RS15935	COG5557	Pfam Polysulphide reductase, NrfD
WM46_RS15940	COG0437	4 iron, 4 sulfur cluster binding
WM46_RS15945	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
WM46_RS15955	COG0840	transmembrane signaling receptor activity
WM46_RS15970	COG0667	Aldo Keto reductase
WM46_RS15995	COG0848	biopolymer transport protein
WM46_RS16000	COG0811	peptide transport
WM46_RS16010	COG0626	cystathionine gamma-synthase activity
WM46_RS16015	COG0586	Pfam SNARE associated Golgi protein
WM46_RS16020	COG2207	Transcriptional regulator
WM46_RS16025	COG1979	alcohol dehydrogenase
WM46_RS16030	COG0656	L-ascorbic acid biosynthetic process
WM46_RS16045	COG0204	Acyl-transferase
WM46_RS16055	COG3111	PFAM Bacterial OB fold (BOF) protein
WM46_RS16060	COG0745	RESPONSE REGULATOR receiver
WM46_RS16065	COG0642	Histidine kinase
WM46_RS16070	COG2249	NAD(P)H dehydrogenase (quinone) activity
WM46_RS16075	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
WM46_RS16080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WM46_RS16085	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
WM46_RS16090	COG2211	Major facilitator Superfamily
WM46_RS16105	COG0187	DNA topoisomerase II activity
WM46_RS16110	COG3150	esterase
WM46_RS16115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WM46_RS16120	COG3151	Protein conserved in bacteria
WM46_RS16125	COG0494	nUDIX hydrolase
WM46_RS16130	COG1538	Outer membrane efflux protein
WM46_RS16145	COG0754	glutathionylspermidine amidase activity
WM46_RS16150	COG3384	dioxygenase
WM46_RS16205	COG3025	triphosphatase activity
WM46_RS16215	COG4991	sh3 domain protein
WM46_RS16230	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WM46_RS16245	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
WM46_RS16250	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
WM46_RS16300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WM46_RS16305	COG0358	DNA primase activity
WM46_RS16330	COG2375	cellular response to nickel ion
WM46_RS16335	COG1695	Transcriptional regulator
WM46_RS16340	COG0840	transmembrane signaling receptor activity
WM46_RS16345	COG0840	transmembrane signaling receptor activity
WM46_RS16355	COG0446	pyridine nucleotide-disulphide oxidoreductase
WM46_RS16355	COG1902	pentaerythritol trinitrate reductase activity
WM46_RS16370	COG1451	nucleotide metabolic process
WM46_RS16375	COG0673	inositol 2-dehydrogenase activity
WM46_RS16380	COG0861	Integral membrane protein TerC family
WM46_RS16395	COG2721	sulfolactate sulfo-lyase activity
WM46_RS16405	COG2271	Major facilitator Superfamily
WM46_RS16410	COG2186	Transcriptional regulator
WM46_RS16415	COG0586	Pfam SNARE associated Golgi protein
WM46_RS16425	COG1422	Protein of unknown function (DUF1090)
WM46_RS16430	COG4575	ribosome binding
WM46_RS16435	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
WM46_RS16445	COG2259	Doxx family
WM46_RS16450	COG0435	Glutathione S-transferase
WM46_RS16455	COG3152	Membrane
WM46_RS16460	COG0583	DNA-binding transcription factor activity
WM46_RS16465	COG1741	Belongs to the pirin family
WM46_RS16475	COG0814	amino acid
WM46_RS16480	COG1760	l-serine dehydratase
WM46_RS16485	COG1882	Formate acetyltransferase
WM46_RS16505	COG0583	DNA-binding transcription factor activity
WM46_RS16515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM46_RS16525	COG1929	Belongs to the glycerate kinase type-1 family
WM46_RS16530	COG2084	Dehydrogenase
WM46_RS16540	COG2271	Major facilitator Superfamily
WM46_RS16545	COG2721	sulfolactate sulfo-lyase activity
WM46_RS16555	COG1175	transmembrane transport
WM46_RS16560	COG0395	ABC-type sugar transport system, permease component
WM46_RS16565	COG3842	ATPase activity
WM46_RS16570	COG0673	inositol 2-dehydrogenase activity
WM46_RS16575	COG1940	carbohydrate kinase activity
WM46_RS16580	COG1349	DNA-binding transcription factor activity
WM46_RS16585	COG1349	DNA-binding transcription factor activity
WM46_RS16595	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS16605	COG3716	PTS system mannose fructose sorbose family IID component
WM46_RS16610	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS16615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WM46_RS16620	COG2222	sugar isomerase
WM46_RS16635	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS16640	COG3715	PTS system
WM46_RS16645	COG3716	PTS system mannose fructose sorbose family IID component
WM46_RS16650	COG0363	glucosamine-6-phosphate deaminase activity
WM46_RS16655	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WM46_RS16675	COG2823	Periplasmic or secreted lipoprotein
WM46_RS16680	COG0701	Predicted permease
WM46_RS16685	COG0702	epimerase
WM46_RS16690	COG0693	protein deglycase activity
WM46_RS16705	COG3153	acetyltransferase
WM46_RS16710	COG3154	lipid carrier protein
WM46_RS16715	COG0826	peptidase U32
WM46_RS16720	COG0826	peptidase U32
WM46_RS16725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WM46_RS16730	COG0814	amino acid
WM46_RS16735	COG0513	Belongs to the DEAD box helicase family
WM46_RS16775	COG0195	Participates in both transcription termination and antitermination
WM46_RS16800	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WM46_RS16810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WM46_RS16815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WM46_RS16825	COG1534	Rna-binding protein
WM46_RS16835	COG2027	D-alanyl-D-alanine carboxypeptidase
WM46_RS16860	COG0142	geranyltranstransferase activity
WM46_RS16865	COG3423	Transcriptional regulator
WM46_RS16875	COG5007	Belongs to the BolA IbaG family
WM46_RS16880	COG3113	response to antibiotic
WM46_RS16885	COG2854	intermembrane phospholipid transfer
WM46_RS16890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WM46_RS16895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WM46_RS16900	COG1127	ABC transporter
WM46_RS16905	COG0530	calcium, potassium:sodium antiporter activity
WM46_RS16915	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WM46_RS16920	COG3117	lipopolysaccharide transmembrane transporter activity
WM46_RS16925	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
WM46_RS16930	COG1137	ATPase activity
WM46_RS16940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WM46_RS16955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS16960	COG0515	serine threonine protein kinase
WM46_RS16970	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
WM46_RS16975	COG0784	Response regulator, receiver
WM46_RS16975	COG2198	Histidine kinase
WM46_RS16975	COG5002	protein histidine kinase activity
WM46_RS16980	COG1242	4 iron, 4 sulfur cluster binding
WM46_RS16985	COG0067	glutamate synthase
WM46_RS16985	COG0069	glutamate synthase activity
WM46_RS16985	COG0070	glutamate synthase
WM46_RS16990	COG0493	'glutamate synthase
WM46_RS16995	COG2731	YhcH YjgK YiaL family protein
WM46_RS17020	COG2186	Transcriptional regulator
WM46_RS17025	COG2969	positive regulation of protein catabolic process
WM46_RS17030	COG0625	glutathione transferase activity
WM46_RS17060	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WM46_RS17065	COG3105	Protein conserved in bacteria
WM46_RS17070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WM46_RS17075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WM46_RS17095	COG2732	(Barnase) inhibitor
WM46_RS17100	COG1012	belongs to the aldehyde dehydrogenase family
WM46_RS17120	COG0583	DNA-binding transcription factor activity
WM46_RS17130	COG2211	Major facilitator Superfamily
WM46_RS17140	COG0312	modulator of DNA gyrase
WM46_RS17145	COG3164	Protein of unknown function
WM46_RS17160	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
WM46_RS17165	COG1792	Involved in formation and maintenance of cell shape
WM46_RS17170	COG1077	Cell shape determining protein MreB Mrl
WM46_RS17185	COG2200	EAL domain
WM46_RS17185	COG2199	diguanylate cyclase activity
WM46_RS17190	COG0604	alcohol dehydrogenase
WM46_RS17210	COG0511	ligase activity, forming carbon-carbon bonds
WM46_RS17215	COG0439	Biotin carboxylase
WM46_RS17225	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WM46_RS17230	COG3924	membrane
WM46_RS17235	COG4145	pantothenate transmembrane transporter activity
WM46_RS17255	COG2189	Belongs to the N(4) N(6)-methyltransferase family
WM46_RS17265	COG1309	transcriptional regulator
WM46_RS17270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM46_RS17275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WM46_RS17285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM46_RS17290	COG4597	amino acid ABC transporter
WM46_RS17295	COG0765	amino acid transport
WM46_RS17300	COG1126	abc transporter atp-binding protein
WM46_RS17340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
WM46_RS17360	COG0551	DNA topoisomerase type I activity
WM46_RS17370	COG0758	DNA mediated transformation
WM46_RS17400	COG3036	rescue of stalled ribosome
WM46_RS17405	COG0789	Transcriptional regulator
WM46_RS17415	COG0203	ribosomal protein L17
WM46_RS17445	COG0201	protein transport
WM46_RS17550	COG0051	transcription antitermination factor activity, RNA binding
WM46_RS17610	COG2964	Protein conserved in bacteria
WM46_RS17615	COG0545	Peptidyl-prolyl cis-trans isomerase
WM46_RS17625	COG1047	Peptidyl-prolyl cis-trans
WM46_RS17630	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
WM46_RS17650	COG0488	(ABC) transporter
WM46_RS17655	COG0429	hydrolase of the alpha beta-hydrolase fold
WM46_RS17665	COG3954	Phosphoribulokinase
WM46_RS17670	COG1765	OsmC-like protein
WM46_RS17690	COG1289	transmembrane transporter activity
WM46_RS17695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WM46_RS17725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WM46_RS17730	COG2146	nitrite reductase [NAD(P)H] activity
WM46_RS17750	COG0180	Tryptophanyl-tRNA synthetase
WM46_RS17760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WM46_RS17765	COG0338	D12 class N6 adenine-specific DNA methyltransferase
WM46_RS17770	COG3266	domain, Protein
WM46_RS17790	COG4796	Type ii and iii secretion system protein
WM46_RS17805	COG3166	PFAM Fimbrial assembly family protein
WM46_RS17810	COG4972	Pilus assembly protein
WM46_RS17815	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
WM46_RS17820	COG0494	nUDIX hydrolase
WM46_RS17830	COG1011	Hydrolase
WM46_RS17835	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
WM46_RS17860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WM46_RS17865	COG2183	response to ionizing radiation
WM46_RS17875	COG1918	ferrous iron import across plasma membrane
WM46_RS17910	COG2610	gluconate transmembrane transporter activity
WM46_RS17915	COG1640	4-alpha-glucanotransferase
WM46_RS17920	COG0058	SHG alpha-glucan phosphorylase activity
WM46_RS17950	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
WM46_RS17955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WM46_RS17960	COG0183	Belongs to the thiolase family
WM46_RS17965	COG1349	DNA-binding transcription factor activity
WM46_RS17980	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WM46_RS17985	COG0371	Dehydrogenase
WM46_RS17995	COG0129	dihydroxy-acid dehydratase activity
WM46_RS18000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WM46_RS18005	COG1414	Transcriptional regulator
WM46_RS18010	COG0058	SHG alpha-glucan phosphorylase activity
WM46_RS18040	COG2095	MarC family integral membrane protein
WM46_RS18045	COG2610	gluconate transmembrane transporter activity
WM46_RS18050	COG3265	gluconokinase activity
WM46_RS18055	COG1609	Transcriptional regulator
WM46_RS18060	COG1741	Belongs to the pirin family
WM46_RS18065	COG0673	inositol 2-dehydrogenase activity
WM46_RS18070	COG1247	-acetyltransferase
WM46_RS18075	COG0405	Gamma-glutamyltransferase
WM46_RS18085	COG0584	glycerophosphoryl diester phosphodiesterase
WM46_RS18110	COG0410	ABC transporter
WM46_RS18115	COG0411	ABC transporter
WM46_RS18120	COG4177	L-phenylalanine transmembrane transporter activity
WM46_RS18130	COG0683	leucine binding
WM46_RS18140	COG1704	LemA family
WM46_RS18145	COG4907	membrane protein (DUF2207)
WM46_RS18150	COG0683	leucine binding
WM46_RS18155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WM46_RS18165	COG2177	Part of the ABC transporter FtsEX involved in
WM46_RS18170	COG2884	Cell division ATP-binding protein ftsE
WM46_RS18175	COG0552	protein localization to endoplasmic reticulum
WM46_RS18180	COG0742	ribosomal rna small subunit methyltransferase
WM46_RS18185	COG3776	membrane
WM46_RS18195	COG3714	YhhN family
WM46_RS18215	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
WM46_RS18225	COG0477	Major facilitator Superfamily
WM46_RS18230	COG0628	permease
WM46_RS18260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WM46_RS18280	COG1216	Glycosyl transferase, family 2
WM46_RS18305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WM46_RS18315	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS18320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WM46_RS18325	COG2091	lysine biosynthetic process via aminoadipic acid
WM46_RS18335	COG3547	Transposase (IS116 IS110 IS902 family)
WM46_RS18385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WM46_RS18390	COG1609	Transcriptional regulator
WM46_RS18395	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WM46_RS18410	COG1575	Belongs to the MenA family. Type 1 subfamily
WM46_RS18425	COG3074	FtsZ-dependent cytokinesis
WM46_RS18430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WM46_RS18440	COG1494	fructose-1,6-bisphosphatase
WM46_RS18450	COG3152	Membrane
WM46_RS18465	COG0471	metal ion transport
WM46_RS18475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WM46_RS18485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM46_RS18490	COG2211	Major facilitator Superfamily
WM46_RS18500	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WM46_RS18515	COG3678	ATP-independent chaperone mediated protein folding
WM46_RS18520	COG0745	RESPONSE REGULATOR receiver
WM46_RS18525	COG2205	protein histidine kinase activity
WM46_RS18530	COG2258	MOSC domain
WM46_RS18535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WM46_RS18545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WM46_RS18585	COG1129	ABC transporter
WM46_RS18590	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM46_RS18595	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM46_RS18600	COG1454	alcohol dehydrogenase
WM46_RS18620	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
WM46_RS18635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS18660	COG0205	6-phosphofructokinase activity
WM46_RS18680	COG0243	molybdopterin cofactor binding
WM46_RS18680	COG3383	formate dehydrogenase (NAD+) activity
WM46_RS18685	COG3383	formate dehydrogenase (NAD+) activity
WM46_RS18685	COG0243	molybdopterin cofactor binding
WM46_RS18690	COG0437	4 iron, 4 sulfur cluster binding
WM46_RS18695	COG2864	formate dehydrogenase
WM46_RS18700	COG2304	oxidoreductase activity
WM46_RS18705	COG5002	protein histidine kinase activity
WM46_RS18710	COG0745	RESPONSE REGULATOR receiver
WM46_RS18725	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WM46_RS18735	COG3609	addiction module antidote protein, CC2985 family
WM46_RS18745	COG0456	acetyltransferase
WM46_RS18750	COG1490	D-aminoacyl-tRNA deacylase activity
WM46_RS18760	COG1011	Hydrolase
WM46_RS18770	COG1349	DNA-binding transcription factor activity
WM46_RS18775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM46_RS18785	COG3684	Belongs to the aldolase LacD family
WM46_RS18790	COG2942	2-epimerase
WM46_RS18795	COG2017	converts alpha-aldose to the beta-anomer
WM46_RS18805	COG1501	Belongs to the glycosyl hydrolase 31 family
WM46_RS18815	COG2211	Major facilitator Superfamily
WM46_RS18820	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WM46_RS18835	COG0174	glutamine synthetase
WM46_RS18840	COG3852	Histidine kinase
WM46_RS18855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WM46_RS18885	COG0204	Acyl-transferase
WM46_RS18900	COG3084	Protein conserved in bacteria
WM46_RS18905	COG0746	molybdenum cofactor guanylyltransferase activity
WM46_RS18910	COG1763	Mo-molybdopterin cofactor biosynthetic process
WM46_RS18940	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
WM46_RS18950	COG1739	Uncharacterized protein family UPF0029
WM46_RS18975	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WM46_RS18990	COG0805	protein transport
WM46_RS19010	COG3165	ubiquinone biosynthetic process from chorismate
WM46_RS19020	COG1322	Protein conserved in bacteria
WM46_RS19030	COG0412	Dienelactone hydrolase
WM46_RS19040	COG0583	DNA-binding transcription factor activity
WM46_RS19045	COG0697	spore germination
WM46_RS19050	COG0561	phosphatase activity
WM46_RS19055	COG2267	carboxylic ester hydrolase activity
WM46_RS19060	COG1280	lysine exporter protein (LysE YggA)
WM46_RS19065	COG1280	lysine exporter protein (LysE YggA)
WM46_RS19100	COG1011	Hydrolase
WM46_RS19105	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WM46_RS19120	COG5567	small periplasmic lipoprotein
WM46_RS19150	COG2959	enzyme of heme biosynthesis
WM46_RS19155	COG3071	HemY protein
WM46_RS19210	COG2244	polysaccharide biosynthetic process
WM46_RS19215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WM46_RS19220	COG0456	acetyltransferase
WM46_RS19225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
WM46_RS19230	COG1088	dTDP-glucose 4,6-dehydratase activity
WM46_RS19235	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
WM46_RS19250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WM46_RS19260	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WM46_RS19270	COG3118	belongs to the thioredoxin family
WM46_RS19305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WM46_RS19325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WM46_RS19335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WM46_RS19340	COG3978	acetolactate synthase activity
WM46_RS19360	COG0606	chelatase, subunit chli
WM46_RS19365	COG3085	chromosome segregation
WM46_RS19405	COG2186	Transcriptional regulator
WM46_RS19410	COG0477	Major facilitator Superfamily
WM46_RS19415	COG1609	Transcriptional regulator
WM46_RS19420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM46_RS19425	COG1879	ABC-type sugar transport system periplasmic component
WM46_RS19430	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM46_RS19435	COG1129	ABC transporter
WM46_RS19440	COG1869	D-ribose catabolic process
WM46_RS19465	COG1522	sequence-specific DNA binding
WM46_RS19470	COG0716	FMN binding
WM46_RS19490	COG3312	ion transport
WM46_RS19515	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WM46_RS19520	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WM46_RS19525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WM46_RS19530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WM46_RS19545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WM46_RS19555	COG0573	inorganic phosphate transmembrane transporter activity
WM46_RS19560	COG0581	inorganic phosphate transmembrane transporter activity
WM46_RS19570	COG0704	Plays a role in the regulation of phosphate uptake
WM46_RS19575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WM46_RS19580	COG2252	PERMEase
WM46_RS19585	COG0431	NADPH-dependent FMN reductase
WM46_RS19590	COG2091	lysine biosynthetic process via aminoadipic acid
WM46_RS19605	COG0814	amino acid
WM46_RS19655	COG0592	DNA-directed DNA polymerase activity
WM46_RS19670	COG0561	phosphatase activity
WM46_RS19675	COG2186	Transcriptional regulator
WM46_RS19680	COG3734	2-keto-3-deoxy-galactonokinase
WM46_RS19685	COG0800	Aldolase
WM46_RS19690	COG4948	Mandelate Racemase Muconate Lactonizing
WM46_RS19695	COG2271	Major facilitator Superfamily
WM46_RS19705	COG0823	Involved in the tonB-independent uptake of proteins
WM46_RS19710	COG5645	(Lipo)protein
WM46_RS19740	COG2211	Major facilitator Superfamily
WM46_RS19745	COG2149	membrane
WM46_RS19755	COG0641	radical SAM
WM46_RS19765	COG2610	gluconate transmembrane transporter activity
WM46_RS19770	COG0583	DNA-binding transcription factor activity
WM46_RS19780	COG2814	Major facilitator Superfamily
WM46_RS19805	COG0028	Belongs to the TPP enzyme family
WM46_RS19810	COG0440	acetolactate synthase activity
WM46_RS19815	COG1349	DNA-binding transcription factor activity
WM46_RS19825	COG0738	Major facilitator superfamily
WM46_RS19835	COG2197	response regulator
WM46_RS19860	COG2252	PERMEase
WM46_RS19885	COG4580	involved in the transport of maltose and maltodextrins
WM46_RS19890	COG1447	Phosphotransferase system cellobiose-specific component IIA
WM46_RS19895	COG2723	6-phospho-beta-galactosidase activity
WM46_RS19900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WM46_RS19910	COG1609	Transcriptional regulator
WM46_RS19940	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS19940	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS19945	COG3715	PTS system
WM46_RS19950	COG3716	PTS system mannose fructose sorbose family IID component
WM46_RS19965	COG1464	Belongs to the NlpA lipoprotein family
WM46_RS19975	COG3121	Chaperone
WM46_RS19985	COG3539	Fimbrial protein
WM46_RS19990	COG3121	Chaperone
WM46_RS20000	COG0697	spore germination
WM46_RS20010	COG1902	pentaerythritol trinitrate reductase activity
WM46_RS20025	COG2211	Major facilitator Superfamily
WM46_RS20030	COG1501	Belongs to the glycosyl hydrolase 31 family
WM46_RS20035	COG0738	Major facilitator superfamily
WM46_RS20045	COG1486	melibiose metabolic process
WM46_RS20050	COG1263	PTS System
WM46_RS20050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS20055	COG2982	Protein involved in outer membrane biogenesis
WM46_RS20060	COG2233	PERMEase
WM46_RS20065	COG0786	glutamate:sodium symporter activity
WM46_RS20070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WM46_RS20075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WM46_RS20080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WM46_RS20100	COG2860	membrane
WM46_RS20105	COG1561	YicC-like family, N-terminal region
WM46_RS20135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WM46_RS20145	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WM46_RS20150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WM46_RS20165	COG1519	Transferase
WM46_RS20170	COG0859	PFAM glycosyl transferase family 9
WM46_RS20175	COG0438	transferase activity, transferring glycosyl groups
WM46_RS20180	COG0515	serine threonine protein kinase
WM46_RS20185	COG4641	Protein conserved in bacteria
WM46_RS20185	COG0438	transferase activity, transferring glycosyl groups
WM46_RS20215	COG0859	PFAM glycosyl transferase family 9
WM46_RS20220	COG3307	-O-antigen
WM46_RS20225	COG0859	PFAM glycosyl transferase family 9
WM46_RS20230	COG0859	PFAM glycosyl transferase family 9
WM46_RS20240	COG0156	8-amino-7-oxononanoate synthase activity
WM46_RS20250	COG1216	Glycosyl transferase, family 2
WM46_RS20255	COG2861	carbohydrate metabolic process
WM46_RS20260	COG4942	peptidase
WM46_RS20270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WM46_RS20275	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WM46_RS20295	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WM46_RS20305	COG2186	Transcriptional regulator
WM46_RS20325	COG3722	fumarate hydratase activity
WM46_RS20340	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS20340	COG2213	PTS system mannitol-specific
WM46_RS20350	COG1566	PFAM secretion protein HlyD family protein
WM46_RS20355	COG0625	glutathione transferase activity
WM46_RS20365	COG3276	selenocysteine insertion sequence binding
WM46_RS20370	COG1454	alcohol dehydrogenase
WM46_RS20375	COG1012	belongs to the aldehyde dehydrogenase family
WM46_RS20390	COG1566	PFAM secretion protein HlyD family protein
WM46_RS20395	COG0583	DNA-binding transcription factor activity
WM46_RS20400	COG3713	MltA-interacting MipA family protein
WM46_RS20410	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM46_RS20415	COG3977	Valine--pyruvate aminotransferase
WM46_RS20420	COG0366	Alpha amylase catalytic
WM46_RS20430	COG2992	FlgJ-related protein
WM46_RS20435	COG1609	Transcriptional regulator
WM46_RS20435	COG2207	Transcriptional regulator
WM46_RS20440	COG4214	carbohydrate transport
WM46_RS20450	COG4213	ABC transporter substrate-binding protein
WM46_RS20460	COG1070	Carbohydrate kinase
WM46_RS20465	COG4682	membrane
WM46_RS20470	COG3274	enterobacterial common antigen metabolic process
WM46_RS20500	COG1278	Cold shock
WM46_RS20505	COG2944	sequence-specific DNA binding
WM46_RS20510	COG2814	Major facilitator Superfamily
WM46_RS20530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM46_RS20540	COG1609	Transcriptional regulator
WM46_RS20545	COG2885	chlorophyll binding
WM46_RS20550	COG0243	molybdopterin cofactor binding
WM46_RS20555	COG0456	acetyltransferase
WM46_RS20560	COG2818	Glycosylase
WM46_RS20565	COG5571	outer membrane autotransporter
WM46_RS20570	COG2223	nitrite transmembrane transporter activity
WM46_RS20575	COG2194	sulfuric ester hydrolase activity
WM46_RS20595	COG0747	negative chemotaxis
WM46_RS20605	COG0601	transmembrane transport
WM46_RS20610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WM46_RS20615	COG0444	Belongs to the ABC transporter superfamily
WM46_RS20620	COG4608	Belongs to the ABC transporter superfamily
WM46_RS20625	COG0814	amino acid
WM46_RS20635	COG2194	sulfuric ester hydrolase activity
WM46_RS20665	COG1215	transferase activity, transferring glycosyl groups
WM46_RS20675	COG3118	belongs to the thioredoxin family
WM46_RS20675	COG0457	Tetratricopeptide repeat
WM46_RS20680	COG2199	diguanylate cyclase activity
WM46_RS20680	COG2200	EAL domain
WM46_RS20695	COG0612	Peptidase, M16
WM46_RS20700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM46_RS20705	COG2200	EAL domain
WM46_RS20710	COG2982	Protein involved in outer membrane biogenesis
WM46_RS20715	COG0477	Major facilitator Superfamily
WM46_RS20725	COG1295	ribonuclease BN
WM46_RS20730	COG0583	DNA-binding transcription factor activity
WM46_RS20735	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS20740	COG2197	response regulator
WM46_RS20745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WM46_RS20755	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
WM46_RS20760	COG1858	cytochrome C peroxidase
WM46_RS20765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WM46_RS20770	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WM46_RS20775	COG0339	signal peptide processing
WM46_RS20790	COG1959	2 iron, 2 sulfur cluster binding
WM46_RS20800	COG0589	response to stress
WM46_RS20810	COG0306	phosphate transporter
WM46_RS20815	COG2081	HI0933 family
WM46_RS20820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM46_RS20825	COG1129	ABC transporter
WM46_RS20825	COG0842	Transport permease protein
WM46_RS20830	COG0842	Transport permease protein
WM46_RS20840	COG0444	Belongs to the ABC transporter superfamily
WM46_RS20845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WM46_RS20850	COG0601	transmembrane transport
WM46_RS20855	COG0747	negative chemotaxis
WM46_RS20865	COG3209	COG3209 Rhs family protein
WM46_RS20880	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
WM46_RS20890	COG0626	cystathionine gamma-synthase activity
WM46_RS20895	COG0527	aspartate kinase activity
WM46_RS20895	COG0460	homoserine dehydrogenase
WM46_RS20905	COG0583	DNA-binding transcription factor activity
WM46_RS20910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
WM46_RS20925	COG0697	spore germination
WM46_RS20930	COG0371	Dehydrogenase
WM46_RS20945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WM46_RS20945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS20945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS20950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM46_RS20955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM46_RS20960	COG1882	Formate acetyltransferase
WM46_RS20965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WM46_RS20970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM46_RS20975	COG2207	Transcriptional regulator
WM46_RS20980	COG2194	sulfuric ester hydrolase activity
WM46_RS20990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WM46_RS20995	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WM46_RS21010	COG0235	Class ii aldolase
WM46_RS21015	COG1349	DNA-binding transcription factor activity
WM46_RS21030	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM46_RS21035	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM46_RS21040	COG3623	hexulose-6-phosphate isomerase
WM46_RS21045	COG1070	Carbohydrate kinase
WM46_RS21050	COG0583	DNA-binding transcription factor activity
WM46_RS21075	COG4206	TonB-dependent receptor
WM46_RS21115	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WM46_RS21155	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WM46_RS21160	COG0250	Participates in transcription elongation, termination and antitermination
WM46_RS21200	COG1447	Phosphotransferase system cellobiose-specific component IIA
WM46_RS21210	COG3706	GGDEF domain
WM46_RS21225	COG2104	thiamine diphosphate biosynthetic process
WM46_RS21230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WM46_RS21260	COG1515	deoxyribonuclease V activity
WM46_RS21280	COG3678	ATP-independent chaperone mediated protein folding
WM46_RS21290	COG2204	response regulator
WM46_RS21295	COG0151	Belongs to the GarS family
WM46_RS21330	COG0456	acetyltransferase
WM46_RS21340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WM46_RS21380	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WM46_RS21385	COG3657	addiction module killer protein
WM46_RS21395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WM46_RS21435	COG1187	pseudouridine synthase activity
WM46_RS21445	COG1349	DNA-binding transcription factor activity
WM46_RS21470	COG4650	regulator
WM46_RS21485	COG1690	Belongs to the RtcB family
WM46_RS21490	COG3541	Predicted nucleotidyltransferase
WM46_RS21495	COG0527	aspartate kinase activity
WM46_RS21540	COG3833	ABC-type maltose transport systems, permease component
WM46_RS21590	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
WM46_RS21600	COG0534	Mate efflux family protein
WM46_RS21605	COG3237	CsbD-like
WM46_RS21610	COG0735	belongs to the Fur family
WM46_RS21620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WM46_RS21635	COG0305	Participates in initiation and elongation during chromosome replication
WM46_RS21640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WM46_RS21645	COG1448	Aminotransferase
WM46_RS21650	COG3700	Belongs to the class B bacterial acid phosphatase family
WM46_RS21655	COG2315	Protein conserved in bacteria
WM46_RS21665	COG0629	single-stranded DNA binding
WM46_RS21675	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
WM46_RS21700	COG0789	Transcriptional regulator
WM46_RS21720	COG2252	PERMEase
WM46_RS21725	COG0025	NhaP-type Na H and K H
WM46_RS21730	COG1943	Transposase
WM46_RS21735	COG0583	DNA-binding transcription factor activity
WM46_RS21740	COG1380	Effector of murein hydrolase LrgA
WM46_RS21745	COG1346	cytolysis
WM46_RS21755	COG3162	membrane
WM46_RS21760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WM46_RS21775	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
WM46_RS21780	COG0437	4 iron, 4 sulfur cluster binding
WM46_RS21785	COG3301	Polysulphide reductase, NrfD
WM46_RS21790	COG1138	Cytochrome C-type biogenesis protein
WM46_RS21795	COG3088	subunit of a heme lyase
WM46_RS21800	COG4235	cytochrome complex assembly
WM46_RS21810	COG1301	dicarboxylic acid transport
WM46_RS21815	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
WM46_RS21830	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
WM46_RS21835	COG0456	acetyltransferase
WM46_RS21845	COG3454	Phosphonate metabolism
WM46_RS21850	COG4778	phosphonate C-P lyase system protein PhnL
WM46_RS21855	COG4107	phosphonate C-P lyase system protein PhnK
WM46_RS21860	COG3627	carbon phosphorus lyase activity
WM46_RS21865	COG3626	phosphonate metabolism
WM46_RS21870	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
WM46_RS21875	COG3624	Phosphonate C-P lyase system protein PhnG
WM46_RS21880	COG2188	Transcriptional regulator
WM46_RS21885	COG3639	organic phosphonate transmembrane transporter activity
WM46_RS21890	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
WM46_RS21895	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
WM46_RS21900	COG2764	glyoxalase bleomycin resistance protein dioxygenase
WM46_RS21905	COG2824	Alkylphosphonate utilization operon protein PhnA
WM46_RS21940	COG0745	RESPONSE REGULATOR receiver
WM46_RS21950	COG0531	amino acid
WM46_RS21955	COG2207	Transcriptional regulator
WM46_RS21960	COG1982	Orn Lys Arg decarboxylase major
WM46_RS21965	COG2169	Transcriptional regulator
WM46_RS21975	COG2211	Major facilitator Superfamily
WM46_RS21985	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
WM46_RS21985	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
WM46_RS21990	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WM46_RS21995	COG4565	transcriptional regulatory protein
WM46_RS22000	COG3290	protein histidine kinase activity
WM46_RS22005	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
WM46_RS22015	COG0243	molybdopterin cofactor binding
WM46_RS22020	COG0437	4 iron, 4 sulfur cluster binding
WM46_RS22025	COG3302	dmso reductase anchor subunit
WM46_RS22030	COG3381	protein complex oligomerization
WM46_RS22035	COG2221	Nitrite and sulphite reductase 4Fe-4S
WM46_RS22035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM46_RS22045	COG3539	Fimbrial protein
WM46_RS22055	COG3188	usher protein
WM46_RS22060	COG3121	Chaperone
WM46_RS22070	COG3539	Fimbrial protein
WM46_RS22100	COG1132	(ABC) transporter
WM46_RS22105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM46_RS22110	COG1136	(ABC) transporter
WM46_RS22110	COG0577	efflux transmembrane transporter activity
WM46_RS22115	COG1538	Outer membrane efflux protein
WM46_RS22120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WM46_RS22135	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS22205	COG0629	single-stranded DNA binding
WM46_RS22245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WM46_RS22260	COG0741	lytic transglycosylase activity
WM46_RS22320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WM46_RS22330	COG0673	inositol 2-dehydrogenase activity
WM46_RS22340	COG2072	flavoprotein involved in K transport
WM46_RS22375	COG2197	response regulator
WM46_RS22430	COG3188	usher protein
WM46_RS22480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WM46_RS22505	COG2990	Protein conserved in bacteria
WM46_RS22535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WM46_RS22545	COG1349	DNA-binding transcription factor activity
WM46_RS22550	COG0561	phosphatase activity
WM46_RS22670	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WM46_RS22690	COG1309	transcriptional regulator
WM46_RS22705	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WM46_RS22710	COG1027	Aspartate ammonia-lyase
WM46_RS22720	COG3030	protein affecting phage T7 exclusion by the F plasmid
WM46_RS22725	COG0531	amino acid
WM46_RS22755	COG1509	lysine 2,3-aminomutase activity
WM46_RS22770	COG5510	response to toxic substance
WM46_RS22785	COG2076	Multidrug Resistance protein
WM46_RS22805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WM46_RS22810	COG1053	succinate dehydrogenase
WM46_RS22820	COG1511	domain protein
WM46_RS22820	COG3264	Mechanosensitive ion channel
WM46_RS22855	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WM46_RS22860	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WM46_RS22860	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WM46_RS22865	COG0802	atpase or kinase
WM46_RS22870	COG0860	N-Acetylmuramoyl-L-alanine amidase
WM46_RS22890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WM46_RS22895	COG0330	HflC and HflK could
WM46_RS22900	COG0330	HflC and HflK could
WM46_RS22905	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
WM46_RS22920	COG0557	exoribonuclease II activity
WM46_RS22925	COG2515	1-aminocyclopropane-1-carboxylate deaminase
WM46_RS22930	COG1794	racemase activity, acting on amino acids and derivatives
WM46_RS22935	COG4521	taurine ABC transporter
WM46_RS22940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WM46_RS22945	COG1116	anion transmembrane transporter activity
WM46_RS22950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WM46_RS22955	COG1960	acyl-CoA dehydrogenase activity
WM46_RS22965	COG3650	response to hydrogen peroxide
WM46_RS22970	COG1073	alpha beta
WM46_RS22980	COG0730	response to heat
WM46_RS22990	COG2965	DNA replication, synthesis of RNA primer
WM46_RS22995	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WM46_RS23010	COG3061	Opacity-associated protein A
WM46_RS23020	COG0545	Peptidyl-prolyl cis-trans isomerase
WM46_RS23025	COG1113	amino acid transport
WM46_RS23035	COG0697	spore germination
WM46_RS23045	COG0702	epimerase
WM46_RS23050	COG1733	regulation of RNA biosynthetic process
WM46_RS23060	COG1218	3'(2'),5'-bisphosphate nucleotidase
WM46_RS23065	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
WM46_RS23085	COG1253	flavin adenine dinucleotide binding
WM46_RS23095	COG0673	inositol 2-dehydrogenase activity
WM46_RS23105	COG0673	inositol 2-dehydrogenase activity
WM46_RS23110	COG0673	inositol 2-dehydrogenase activity
WM46_RS23115	COG1609	Transcriptional regulator
WM46_RS23125	COG0729	surface antigen
WM46_RS23130	COG2911	Protein conserved in bacteria
WM46_RS23135	COG2105	PFAM AIG2 family protein
WM46_RS23145	COG1879	ABC-type sugar transport system periplasmic component
WM46_RS23150	COG1129	ABC transporter
WM46_RS23155	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM46_RS23160	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM46_RS23165	COG0840	transmembrane signaling receptor activity
WM46_RS23175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WM46_RS23185	COG0312	modulator of DNA gyrase
WM46_RS23190	COG3783	Cytochrome b(562)
WM46_RS23225	COG3964	amidohydrolase
WM46_RS23240	COG3711	transcriptional antiterminator
WM46_RS23240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS23245	COG3077	Addiction module antitoxin, RelB DinJ family
WM46_RS23250	COG2026	Addiction module toxin, RelE StbE family
WM46_RS23255	COG0602	queuosine metabolic process
WM46_RS23270	COG0366	Alpha amylase catalytic
WM46_RS23275	COG1263	PTS System
WM46_RS23275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS23290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WM46_RS23325	COG1438	arginine binding
WM46_RS23335	COG3457	Alanine racemase
WM46_RS23350	COG2235	arginine
WM46_RS23355	COG2731	YhcH YjgK YiaL family protein
WM46_RS23365	COG3005	denitrification pathway
WM46_RS23370	COG0243	molybdopterin cofactor binding
WM46_RS23405	COG0525	valine-tRNA ligase activity
WM46_RS23410	COG2927	DNA polymerase III (CHI subunit)
WM46_RS23425	COG0795	lipopolysaccharide-transporting ATPase activity
WM46_RS23430	COG0795	lipopolysaccharide-transporting ATPase activity
WM46_RS23435	COG0433	COG0433 Predicted ATPase
WM46_RS23440	COG1609	Transcriptional regulator
WM46_RS23445	COG2610	gluconate transmembrane transporter activity
WM46_RS23450	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS23455	COG1063	alcohol dehydrogenase
WM46_RS23460	COG3265	gluconokinase activity
WM46_RS23465	COG1064	alcohol dehydrogenase
WM46_RS23475	COG0582	viral genome integration into host DNA
WM46_RS23485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS23485	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS23490	COG1082	Xylose isomerase domain protein TIM barrel
WM46_RS23495	COG1073	alpha beta
WM46_RS23500	COG4948	Mandelate Racemase Muconate Lactonizing
WM46_RS23515	COG2271	Major facilitator Superfamily
WM46_RS23520	COG2084	Dehydrogenase
WM46_RS23525	COG0445	tRNA wobble uridine modification
WM46_RS23530	COG0129	dihydroxy-acid dehydratase activity
WM46_RS23535	COG2186	Transcriptional regulator
WM46_RS23545	COG4948	Mandelate Racemase Muconate Lactonizing
WM46_RS23555	COG4948	Mandelate Racemase Muconate Lactonizing
WM46_RS23570	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS23605	COG3596	GTP binding
WM46_RS23630	COG2003	Belongs to the UPF0758 family
WM46_RS23725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WM46_RS23730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WM46_RS23735	COG2271	Major facilitator Superfamily
WM46_RS23760	COG0477	Major facilitator Superfamily
WM46_RS23765	COG3204	pilus organization
WM46_RS23775	COG1924	4 iron, 4 sulfur cluster binding
WM46_RS23780	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
WM46_RS23790	COG2733	membrane
WM46_RS23795	COG0583	DNA-binding transcription factor activity
WM46_RS23800	COG1301	dicarboxylic acid transport
WM46_RS23805	COG0626	cystathionine gamma-synthase activity
WM46_RS23810	COG2814	Major facilitator Superfamily
WM46_RS23825	COG1063	alcohol dehydrogenase
WM46_RS23830	COG2271	Major facilitator Superfamily
WM46_RS23835	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS23870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WM46_RS23875	COG5457	Domain of unknown function (DUF1127)
WM46_RS23885	COG1566	PFAM secretion protein HlyD family protein
WM46_RS23895	COG0523	cobalamin synthesis protein
WM46_RS23900	COG2879	small protein
WM46_RS23905	COG1966	Carbon starvation protein
WM46_RS23915	COG0840	transmembrane signaling receptor activity
WM46_RS23925	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WM46_RS23935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WM46_RS23940	COG1802	Transcriptional regulator
WM46_RS23945	COG1063	alcohol dehydrogenase
WM46_RS23960	COG1484	DNA-dependent DNA replication
WM46_RS23975	COG2966	Psort location CytoplasmicMembrane, score
WM46_RS23985	COG2169	Transcriptional regulator
WM46_RS23985	COG1917	Cupin 2, conserved barrel domain protein
WM46_RS23990	COG2197	response regulator
WM46_RS23995	COG2197	response regulator
WM46_RS24000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WM46_RS24005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WM46_RS24010	COG4114	ferric iron reductase
WM46_RS24045	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
WM46_RS24050	COG0456	acetyltransferase
WM46_RS24055	COG1011	Hydrolase
WM46_RS24065	COG2823	Periplasmic or secreted lipoprotein
WM46_RS24070	COG5487	UPF0391 membrane protein
WM46_RS24075	COG4667	esterase of the alpha-beta hydrolase superfamily
WM46_RS24080	COG0084	hydrolase, TatD family'
WM46_RS24085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WM46_RS24090	COG1328	CTP reductase activity
WM46_RS24120	COG3726	membrane protein affecting hemolysin expression
WM46_RS24125	COG0560	Phosphoserine phosphatase
WM46_RS24155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WM46_RS24160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WM46_RS24185	COG0006	proline dipeptidase activity
WM46_RS24190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WM46_RS24195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WM46_RS24215	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS24220	COG2723	6-phospho-beta-galactosidase activity
WM46_RS24225	COG1737	Transcriptional regulator
WM46_RS24235	COG1272	protein, Hemolysin III
WM46_RS24245	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WM46_RS24255	COG0716	FMN binding
WM46_RS24260	COG4974	Belongs to the 'phage' integrase family
WM46_RS24270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WM46_RS24285	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
WM46_RS24290	COG2233	PERMEase
WM46_RS24295	COG2252	PERMEase
WM46_RS24300	COG0402	S-adenosylhomocysteine deaminase activity
WM46_RS24305	COG2233	PERMEase
WM46_RS24310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WM46_RS24310	COG2080	2 iron, 2 sulfur cluster binding
WM46_RS24315	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WM46_RS24320	COG0402	S-adenosylhomocysteine deaminase activity
WM46_RS24325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM46_RS24325	COG0493	'glutamate synthase
WM46_RS24330	COG2068	MobA-Related Protein
WM46_RS24335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WM46_RS24340	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
WM46_RS24340	COG3608	succinylglutamate desuccinylase aspartoacylase
WM46_RS24345	COG0549	Belongs to the carbamate kinase family
WM46_RS24355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WM46_RS24360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WM46_RS24365	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WM46_RS24370	COG3829	transcription factor binding
WM46_RS24375	COG2080	2 iron, 2 sulfur cluster binding
WM46_RS24380	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WM46_RS24385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WM46_RS24390	COG4942	peptidase
WM46_RS24420	COG4977	sequence-specific DNA binding
WM46_RS24420	COG1917	Cupin 2, conserved barrel domain protein
WM46_RS24430	COG1653	transport
WM46_RS24435	COG3842	ATPase activity
WM46_RS24440	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WM46_RS24445	COG0395	ABC-type sugar transport system, permease component
WM46_RS24450	COG1175	transmembrane transport
WM46_RS24455	COG1609	Transcriptional regulator
WM46_RS24465	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS24470	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WM46_RS24485	COG0583	DNA-binding transcription factor activity
WM46_RS24490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WM46_RS24495	COG0700	Nucleoside recognition
WM46_RS24500	COG3366	ferrous iron transmembrane transporter activity
WM46_RS24505	COG2197	response regulator
WM46_RS24510	COG2205	protein histidine kinase activity
WM46_RS24510	COG2198	Histidine kinase
WM46_RS24510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM46_RS24510	COG0784	Response regulator, receiver
WM46_RS24525	COG3121	Chaperone
WM46_RS24540	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WM46_RS24550	COG0583	DNA-binding transcription factor activity
WM46_RS24555	COG2329	Antibiotic biosynthesis monooxygenase
WM46_RS24570	COG2211	Major facilitator Superfamily
WM46_RS24590	COG3539	Fimbrial protein
WM46_RS24595	COG3539	Fimbrial protein
WM46_RS24600	COG3539	Fimbrial protein
WM46_RS24605	COG3188	usher protein
WM46_RS24610	COG3121	Chaperone
WM46_RS24615	COG3539	Fimbrial protein
WM46_RS24625	COG4974	Belongs to the 'phage' integrase family
WM46_RS24630	COG0582	viral genome integration into host DNA
WM46_RS24645	COG3121	Chaperone
WM46_RS24660	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
WM46_RS24680	COG3710	Transcriptional regulator
WM46_RS24685	COG3592	Divergent 4Fe-4S mono-cluster
WM46_RS24690	COG2388	GCN5-related N-acetyl-transferase
WM46_RS24705	COG3188	usher protein
WM46_RS24735	COG2771	luxR family
WM46_RS24750	COG0814	amino acid
WM46_RS24765	COG0183	Belongs to the thiolase family
WM46_RS24775	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS24785	COG1794	racemase activity, acting on amino acids and derivatives
WM46_RS24790	COG0583	DNA-binding transcription factor activity
WM46_RS24800	COG1609	Transcriptional regulator
WM46_RS24835	COG0667	Aldo Keto reductase
WM46_RS24845	COG0861	Integral membrane protein TerC family
WM46_RS24880	COG2165	general secretion pathway protein
WM46_RS24885	COG4795	General secretion pathway protein
WM46_RS24895	COG4967	type IV pilus modification protein PilV
WM46_RS24900	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WM46_RS24905	COG1025	Belongs to the peptidase M16 family
WM46_RS24910	COG1074	ATP-dependent DNA helicase activity
WM46_RS24915	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WM46_RS24920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WM46_RS24920	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WM46_RS24930	COG0860	N-Acetylmuramoyl-L-alanine amidase
WM46_RS24950	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WM46_RS24955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WM46_RS24960	COG2166	iron-sulfur cluster assembly
WM46_RS24965	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WM46_RS24975	COG0583	DNA-binding transcription factor activity
WM46_RS24980	COG2363	Small membrane protein
WM46_RS24990	COG1349	DNA-binding transcription factor activity
WM46_RS25010	COG1129	ABC transporter
WM46_RS25015	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM46_RS25030	COG0235	Class ii aldolase
WM46_RS25040	COG1760	l-serine dehydratase
WM46_RS25045	COG0814	amino acid
WM46_RS25050	COG1611	Belongs to the LOG family
WM46_RS25065	COG3098	single-species biofilm formation
WM46_RS25070	COG0564	pseudouridine synthase activity
WM46_RS25075	COG0716	FMN binding
WM46_RS25085	COG2271	Major facilitator Superfamily
WM46_RS25090	COG4948	Mandelate Racemase Muconate Lactonizing
WM46_RS25095	COG4948	Mandelate Racemase Muconate Lactonizing
WM46_RS25100	COG1929	Belongs to the glycerate kinase type-1 family
WM46_RS25105	COG3850	Histidine kinase
WM46_RS25105	COG3437	response regulator, receiver
WM46_RS25105	COG2205	protein histidine kinase activity
WM46_RS25105	COG4999	Histidine kinase
WM46_RS25115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WM46_RS25120	COG3956	TIGRFAM MazG family protein
WM46_RS25135	COG1737	Transcriptional regulator
WM46_RS25140	COG1263	PTS System
WM46_RS25140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS25140	COG2190	(PTS) system
WM46_RS25145	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
WM46_RS25150	COG0602	queuosine metabolic process
WM46_RS25155	COG1070	Carbohydrate kinase
WM46_RS25160	COG2223	nitrite transmembrane transporter activity
WM46_RS25165	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS25170	COG0277	FAD linked oxidase domain protein
WM46_RS25175	COG0477	Major facilitator Superfamily
WM46_RS25180	COG2086	electron transfer activity
WM46_RS25185	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
WM46_RS25190	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
WM46_RS25195	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
WM46_RS25200	COG0644	oxidoreductase
WM46_RS25205	COG0720	synthase
WM46_RS25230	COG2234	aminopeptidase activity
WM46_RS25290	COG1388	LysM domain
WM46_RS25290	COG4942	peptidase
WM46_RS25295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WM46_RS25305	COG0163	prenyltransferase activity
WM46_RS25325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WM46_RS25330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WM46_RS25335	COG1121	(ABC) transporter
WM46_RS25360	COG0309	Hydrogenase expression formation protein (HypE)
WM46_RS25365	COG0409	Hydrogenase expression formation protein
WM46_RS25370	COG0298	carbon dioxide binding
WM46_RS25375	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WM46_RS25380	COG0375	protein maturation
WM46_RS25390	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM46_RS25395	COG0651	ATP synthesis coupled electron transport
WM46_RS25400	COG0650	Formate hydrogenlyase subunit 4
WM46_RS25405	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
WM46_RS25405	COG3261	NADH dehydrogenase
WM46_RS25410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WM46_RS25415	COG3260	NADH ubiquinone oxidoreductase 20
WM46_RS25425	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
WM46_RS25435	COG2723	6-phospho-beta-galactosidase activity
WM46_RS25440	COG1263	PTS System
WM46_RS25440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM46_RS25445	COG1609	Transcriptional regulator
WM46_RS25450	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM46_RS25455	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
WM46_RS25475	COG0517	IMP dehydrogenase activity
WM46_RS25475	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WM46_RS25480	COG1349	DNA-binding transcription factor activity
WM46_RS25485	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM46_RS25490	COG1028	Short-chain dehydrogenase reductase Sdr
WM46_RS25500	COG3732	PTS system glucitol sorbitol-specific
WM46_RS25505	COG3730	PTS system glucitol sorbitol-specific
WM46_RS25510	COG2951	lytic endotransglycosylase activity
WM46_RS25515	COG1546	Belongs to the CinA family
WM46_RS25535	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
WM46_RS25570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WM46_RS25575	COG1238	metal cluster binding
WM46_RS25590	COG2814	Major facilitator Superfamily
WM46_RS25595	COG1566	PFAM secretion protein HlyD family protein
WM46_RS25600	COG1846	Transcriptional regulator
WM46_RS25610	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
WM46_RS25615	COG2814	Major facilitator Superfamily
WM46_RS25625	COG4176	ABC-type proline glycine betaine transport system permease component
WM46_RS25660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WM46_RS25670	COG4575	ribosome binding
WM46_RS25690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WM46_RS25695	COG0640	Transcriptional regulator
WM46_RS25700	COG0401	homolog of Blt101
WM46_RS25705	COG1652	LysM domain
WM46_RS25710	COG1802	Transcriptional regulator
WM46_RS25715	COG1113	amino acid transport
WM46_RS25720	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WM46_RS25725	COG1012	belongs to the aldehyde dehydrogenase family
WM46_RS25730	COG0579	oxidoreductase
WM46_RS25790	COG2200	EAL domain
WM46_RS25795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WM46_RS25800	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WM46_RS25830	COG2916	Histone family protein nucleoid-structuring protein H-NS
WM46_RS26035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WM46_RS26090	COG4973	Belongs to the 'phage' integrase family. XerC subfamily